locus_tag old_locus_tag gene Name start end strand product note type ID NCBI SH03_RS00005 SH03_00005 rpmH rpmH 607 747 + 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00005 SH03_RS00010 SH03_00010 rnpA rnpA 764 1123 + ribonuclease P protein component protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00010 SH03_RS00015 SH03_00015 SH03_RS00015 1087 1344 + membrane protein insertion efficiency factor YidD gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00015 SH03_RS00020 SH03_00020 SH03_RS00020 1347 2993 + protein translocase component YidC functions to insert inner membrane proteins into the IM in Escherichia coli%3B interacts with transmembrane segments%3B functions in both Sec-dependent and -independent membrane insertion%3B similar to Oxa1p in mitochondria gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00020 SH03_RS00025 SH03_00025 trmE trmE 3099 4463 + tRNA modification GTPase MnmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00025 SH03_RS00030 SH03_00030 SH03_RS00030 4706 4780 + tryptophanase leader peptide gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00030 SH03_RS00035 SH03_00035 tnaA tnaA 5001 6416 + tryptophanase tryptophan indole-lyase%3B catalyzes the formation of indole and pyruvate from tryptophan%3B also has xysteine desulfhydrase activity gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00035 SH03_RS00040 SH03_00040 SH03_RS00040 6507 7754 + low affinity tryptophan permease tryptophan transporter of high affinity gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00040 SH03_RS00045 SH03_00045 SH03_RS00045 7886 9061 + multidrug resistance protein MdtL Confers resistance to chloramphenicol gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00045 SH03_RS00050 SH03_00050 SH03_RS00050 9036 9995 + transcriptional regulator Involved in anaerobic NO protection gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00050 SH03_RS00055 SH03_00055 SH03_RS00055 10152 10901 + 4'-phosphopantetheinyl transferase gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00055 SH03_RS00060 SH03_00060 SH03_RS00060 10923 11489 + chromate reductase gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00060 SH03_RS00065 SH03_00065 SH03_RS00065 11543 12880 - adenine permease AdeP involved in the transport or adenine gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00065 SH03_RS00070 SH03_00070 SH03_RS00070 13045 13710 + 6-phosphogluconate phosphatase YieH%3B catalyzes the dephosphorylation of phosphoenolpyruvate%2C AMP and p-nitrophenyl phosphate%3B purine and pyrimidine nucleotides are secondary substrates%3B member of the haloacid dehalogenase-like hydrolases superfamily gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00070 SH03_RS00075 SH03_00075 SH03_RS00075 13777 14244 + protein CbrB might be involved in hypersensitivity to nitrofurzone gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00075 SH03_RS00080 SH03_00080 SH03_RS00080 14293 14880 + hypothetical protein gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00080 SH03_RS00085 SH03_00085 SH03_RS00085 14942 15664 - 6-phosphogluconolactonase gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00085 SH03_RS00090 SH03_00090 SH03_RS00090 15679 16848 - xylanase gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00090 SH03_RS00095 SH03_00095 SH03_RS00095 16875 18491 - porin BglH gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00095 SH03_RS00100 SH03_00100 SH03_RS00100 18560 19972 - 6-phospho-beta-glucosidase BglB gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00100 SH03_RS00105 SH03_00105 SH03_RS00105 19991 21868 - PTS beta-glucoside EIIBCA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00105 SH03_RS00110 SH03_00110 SH03_RS00110 22002 22838 - cryptic beta-glucoside bgl operon antiterminator positive regulator of the beta-glucoside operon%3B transcriptional antiterminator gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00110 SH03_RS00115 SH03_00115 SH03_RS00115 23124 23849 - phosphate-specific transport system accessory protein PhoU regulates several genes involved in high affinity phosphate uptake%3B under conditions of high phosphate concentrations downregulates the PHO regulon gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00115 SH03_RS00120 SH03_00120 SH03_RS00120 23864 24637 - phosphate import ATP-binding protein PstB gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00120 SH03_RS00125 SH03_00125 pstA pstA 24820 25710 - phosphate ABC transporter permease Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00125 SH03_RS00130 SH03_00130 pstC pstC 25710 26669 - phosphate ABC transporter permease part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00130 SH03_RS00135 SH03_00135 SH03_RS00135 26756 27796 - phosphate-binding protein gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00135 SH03_RS00140 SH03_00140 SH03_RS00140 28110 29939 - glutamine--fructose-6-phosphate aminotransferase [isomerizing] Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00140 SH03_RS00145 SH03_00145 glmU glmU 30101 31471 - bifunctional protein GlmU forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00145 SH03_RS00150 SH03_00150 atpC atpC 31824 32243 - ATP synthase epsilon chain part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00150 SH03_RS00155 SH03_00155 SH03_RS00155 32264 33646 - ATP synthase subunit beta gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00155 SH03_RS00160 SH03_00160 SH03_RS00160 33673 34536 - ATP synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00160 SH03_RS00165 SH03_00165 SH03_RS00165 34587 36128 - ATP synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00165 SH03_RS00170 SH03_00170 SH03_RS00170 36141 36674 - ATP synthase subunit delta Produces ATP from ADP in the presence of a proton gradient across the membrane%3B the delta subunit is part of the catalytic core of the ATP synthase complex gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00170 SH03_RS00175 SH03_00175 SH03_RS00175 36689 37159 - ATP synthase subunit b Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00175 SH03_RS00180 SH03_00180 SH03_RS00180 37221 37460 - ATP synthase subunit c Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00180 SH03_RS00185 SH03_00185 SH03_RS00185 37507 38322 - ATP synthase subunit a Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00185 SH03_RS00190 SH03_00190 SH03_RS00190 38331 38711 - ATP synthase I Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00190 SH03_RS00195 SH03_00195 gidB gidB 39328 39951 - ribosomal RNA small subunit methyltransferase G glucose-inhibited division protein B%3B SAM-dependent methyltransferase%3B methylates the N7 position of guanosine in position 527 of 16S rRNA gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00195 SH03_RS00200 SH03_00200 gidA gidA 40015 41904 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GidA%3B glucose-inhibited cell division protein A%3B involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00200 SH03_RS00205 SH03_00205 SH03_RS00205 42283 42726 - protein MioC An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00205 SH03_RS00210 SH03_00210 SH03_RS00210 42816 43274 - AsnC family transcriptional regulator transcriptional repressor of asnA which codes for aspartate-ammonia ligase gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00210 SH03_RS00215 SH03_00215 SH03_RS00215 43426 44418 + aspartate--ammonia ligase catalyzes the formation of asparagine from aspartate and ammonia gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00215 SH03_RS00220 SH03_00220 SH03_RS00220 44423 45874 - protein ViaA contains a von Willibrand factor type A domain%3B stimulates the ATPase activity of RavA gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00220 SH03_RS00225 SH03_00225 SH03_RS00225 45868 47364 - ATPase RavA interacts with LdcI%2C lysine decarboxylase%3B may be active in late log/ early stationary phase gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00225 SH03_RS00230 SH03_00230 trkD trkD 47587 49455 + low affinity potassium transport system protein kup Responsible for the low-affinity transport of potassium into the cell%3B involved in potassium ion uptake under hyper-osmotic stress at a low pH gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00230 SH03_RS00235 SH03_00235 SH03_RS00235 49622 50041 + D-ribose pyranase cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose%3B RbsD is required for efficient ribose utilization in E. coli%3B rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00235 SH03_RS00240 SH03_00240 SH03_RS00240 50049 51554 + ribose import ATP-binding protein RbsA gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00240 SH03_RS00245 SH03_00245 rbsC rbsC 51559 52524 + ribose ABC transporter permease functions to transport ribose at high affinity%3B forms a complex with RbsA2C2B gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00245 SH03_RS00250 SH03_00250 SH03_RS00250 52549 53439 + D-ribose-binding periplasmic protein periplasmic substrate-binding component of the ATP-dependent ribose transport system gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00250 SH03_RS00255 SH03_00255 SH03_RS00255 53565 54494 + ribokinase catalyzes the formation of D-ribose 5-phosphate from ribose gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00255 SH03_RS00260 SH03_00260 SH03_RS00260 54507 55490 + LacI family transcriptional regulator binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00260 SH03_RS00265 SH03_00265 SH03_RS00265 55456 56883 - transporter HsrA gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00265 SH03_RS00270 SH03_00270 SH03_RS00270 56906 57598 - transcriptional regulator gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00270 SH03_RS00275 SH03_00275 SH03_RS00275 58077 59632 + 16S ribosomal RNA rRNA gene54 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00275 SH03_RS00280 SH03_00280 SH03_RS00280 59706 59781 + tRNA-Glu tRNA gene55 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00280 SH03_RS00285 SH03_00285 SH03_RS00285 59966 62890 + 23S ribosomal RNA rRNA gene56 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00285 SH03_RS00290 SH03_00290 SH03_RS00290 62973 63088 + 5S ribosomal RNA rRNA gene57 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00290 SH03_RS00295 SH03_00295 SH03_RS00295 63143 63219 + tRNA-Asp tRNA gene58 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00295 SH03_RS00300 SH03_00300 SH03_RS00300 63228 63303 + tRNA-Trp tRNA gene59 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00300 SH03_RS00305 SH03_00305 SH03_RS00305 63399 64238 - transcriptional regulator Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00305 SH03_RS00310 SH03_00310 SH03_RS00310 64357 64695 + hypothetical protein gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00310 SH03_RS00315 SH03_00315 SH03_RS00315 64720 66240 - magnesium chelatase and transcriptional regulator among the AAA+ ATPases%2C the YifB protease family belongs to the Helix 2 insert clade%3B unknown function gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00315 SH03_RS00320 SH03_00320 SH03_RS00320 66593 66691 + IlvGMEDA operon leader peptide gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00320 SH03_RS00325 SH03_RS00325 SH03_RS00325 66831 68475 + acetolactate synthase catalytic subunit catalyzes the formation of 2-acetolactate from pyruvate%3B also known as acetolactate synthase large subunit gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00325 SH03_RS00330 SH03_00330 ilvM ilvM 68472 68735 + acetolactate synthase isozyme 2 small subunit gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00330 SH03_RS00335 SH03_00335 SH03_RS00335 68755 69684 + branched-chain-amino-acid aminotransferase gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00335 SH03_RS00340 SH03_00340 SH03_RS00340 69749 71599 + dihydroxy-acid dehydratase catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00340 SH03_RS00345 SH03_00345 SH03_RS00345 71602 73146 + L-threonine dehydratase biosynthetic IlvA threonine deaminase%3B threonine dehydratase%3B in Escherichia coli%2C IlvA is part of the isoleucine biosynthetic pathway gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00345 SH03_RS00350 SH03_00350 SH03_RS00350 73198 74091 - transcriptional regulator participates in controlling several genes involved in isoleucine and valine biosynthesis%3B activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00350 SH03_RS00355 SH03_00355 SH03_RS00355 74241 75716 + ketol-acid reductoisomerase catalyzes the formation of (R)-2%2C3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00355 SH03_RS00360 SH03_00360 SH03_RS00360 75803 76084 - peptidyl-prolyl cis-trans isomerase rotamase C%3B accelerates isomerization of the peptidyl prolyl bond gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00360 SH03_RS00365 SH03_RS00365 SH03_RS00365 76283 76731 - hypothetical protein gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00365 SH03_RS00370 SH03_00370 SH03_RS00370 76948 78969 + ATP-dependent DNA helicase Rep single-stranded DNA-dependent ATPase%3B initiates unwinding at a nick in the DNA%3B involved in DNA replication gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00370 SH03_RS00375 SH03_00375 SH03_RS00375 79016 80500 - guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase catalyzes the conversion of guanosine 5'-triphosphate%2C3'-diphosphate (pppGpp) to guanosine 5'-diphosphate%2C3'-diphosphate (ppGpp)%3B pppGpp and ppGpp control the stringent response during amino acid starvation gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00375 SH03_RS00380 SH03_00380 SH03_RS00380 80636 81901 - ATP-dependent RNA helicase RhlB enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome%2C a multi-enzyme complex important in RNA processing and messenger RNA degradation gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00380 SH03_RS00385 SH03_00385 trxA trxA 82032 82361 + thioredoxin gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00385 SH03_RS00390 SH03_00390 SH03_RS00390 82502 82603 + rho operon leader peptide gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00390 SH03_RS00395 SH03_00395 rho rho 82688 83947 + transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00395 SH03_RS00400 SH03_00400 SH03_RS00400 83957 84175 + hypothetical protein gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00400 SH03_RS00405 SH03_00405 SH03_RS00405 84187 85290 + undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase catalyzes the formation of alpha-N-acetylglucosaminyl-pyrophosphoryl-undecaprenyl from alpha-N-acetylglucosaminyl 1-phosphate and the lipid carrier undecaprenyl phosphate gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00405 SH03_RS00410 SH03_00410 SH03_RS00410 85302 86348 + LPS biosynthesis protein Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00410 SH03_RS00415 SH03_00415 SH03_RS00415 86449 87534 + UDP-N-acetylglucosamine 2-epimerase gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00415 SH03_RS00420 SH03_00420 wecC wecC 87531 88793 + UDP-N-acetyl-D-mannosamine dehydrogenase catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00420 SH03_RS00425 SH03_00425 SH03_RS00425 88793 89860 + dTDP-glucose 4%2C6-dehydratase gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00425 SH03_RS00430 SH03_00430 SH03_RS00430 89879 90760 + glucose-1-phosphate thymidylyltransferase 2 gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00430 SH03_RS00435 SH03_00435 SH03_RS00435 90738 91412 + dTDP-fucosamine acetyltransferase gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00435 SH03_RS00440 SH03_00440 SH03_RS00440 91417 92547 + dTDP-4-amino-4%2C6-dideoxygalactose aminotransferase catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00440 SH03_RS00445 SH03_00445 SH03_RS00445 92549 93799 + protein WzxE involved in the movement of lipid III across the membrane gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00445 SH03_RS00450 SH03_00450 SH03_RS00450 93796 94875 + TDP-N-acetylfucosamine--lipid II N-acetylfucosaminyltransferase catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00450 SH03_RS00455 SH03_00455 SH03_RS00455 94872 96224 + ECA polysaccharide chain elongation protein enterobacterial common antigen polymerase gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00455 SH03_RS00460 SH03_00460 SH03_RS00460 96227 96967 + UDP-N-acetyl-D-mannosaminuronic acid transferase gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00460 SH03_RS00465 SH03_00465 SH03_RS00465 97158 98543 + transporter involved in the transport across the cytoplasmic membrane of D-alanine%2C D-serine and glycine gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00465 SH03_RS00470 SH03_00470 SH03_RS00470 98646 98722 + tRNA-Arg tRNA gene93 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00470 SH03_RS00475 SH03_00475 SH03_RS00475 98781 98856 + tRNA-His tRNA gene94 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00475 SH03_RS00480 SH03_00480 SH03_RS00480 98877 98963 + tRNA-Leu tRNA gene95 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00480 SH03_RS00485 SH03_00485 SH03_RS00485 99006 99082 + tRNA-Pro tRNA gene96 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00485 SH03_RS00490 SH03_00490 SH03_RS00490 99229 100464 + anaerobic sulfatase maturase AslB gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00490 SH03_RS00495 SH03_00495 SH03_RS00495 100623 102278 - arylsulfatase gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00495 SH03_RS00500 SH03_00500 SH03_RS00500 102957 104153 - heme biosynthesis protein HemY gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00500 SH03_RS00505 SH03_00505 SH03_RS00505 104156 105337 - heme biosynthesis operon protein HemX gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00505 SH03_RS00510 SH03_00510 hemD hemD 105359 106099 - uroporphyrinogen III methyltransferase catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane%3B functions in tetrapyrrole and heme biosynthesis gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00510 SH03_RS00515 SH03_00515 hemC hemC 106096 107037 - porphobilinogen deaminase transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00515 SH03_RS00520 SH03_00520 cyaA cyaA 107424 109970 + adenylate cyclase catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00520 SH03_RS00525 SH03_00525 cyaY cyaY 110010 110330 - protein CyaY iron-dependent inhibitor of iron-sulfur cluster formation%3B iron-binding and oxidizing protein%3B defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease%3B based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00525 SH03_RS00530 SH03_00530 SH03_RS00530 110793 110996 + membrane protein gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00530 SH03_RS00535 SH03_00535 dapF dapF 111033 111857 + diaminopimelate epimerase involved in lysine biosynthesis%3B DAP epimerase%3B produces DL-diaminopimelate from LL-diaminopimelate gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00535 SH03_RS00540 SH03_00540 SH03_RS00540 111854 112561 + DUF484 domain-containing protein gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00540 SH03_RS00545 SH03_00545 xerC xerC 112558 113454 + tyrosine recombinase XerC site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00545 SH03_RS00550 SH03_00550 SH03_RS00550 113454 114170 + flavin mononucleotide phosphatase YigB YigB%3B member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein%3B unknown function gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00550 SH03_RS00555 SH03_00555 uvrD uvrD 114254 116416 + DNA helicase II unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present%3B involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00555 SH03_RS00560 SH03_00560 SH03_RS00560 116563 117327 - DUF2233 domain-containing protein gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00560 SH03_RS00565 SH03_00565 SH03_RS00565 117340 117453 + hypothetical protein gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00565 SH03_RS00570 SH03_00570 SH03_RS00570 117697 118647 + magnesium transporter CorA responsible for the influx of magnesium ions gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00570 SH03_RS00575 SH03_00575 SH03_RS00575 118690 119070 - DUF2628 domain-containing protein gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00575 SH03_RS00580 SH03_00580 SH03_RS00580 119084 119464 - hypothetical protein gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00580 SH03_RS00585 SH03_00585 SH03_RS00585 119559 120449 - protein RarD gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00585 SH03_RS00590 SH03_00590 SH03_RS00590 120501 120968 - hypothetical protein gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00590 SH03_RS00595 SH03_00595 SH03_RS00595 121133 122002 + phospholipase A1 catalyzes the hydrolysis of phosphatidylcholine gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00595 SH03_RS00600 SH03_00600 SH03_RS00600 122135 123964 + ATP-dependent DNA helicase RecQ functions in blocking illegitimate recombination%2C enhancing topoisomerase activity%2C initiating SOS signaling and clearing blocked replication forks%3B component of the RecF recombinational pathway gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00600 SH03_RS00605 SH03_00605 SH03_RS00605 124028 124648 + threonine efflux protein gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00605 SH03_RS00610 SH03_00610 rhtB rhtB 124710 125330 - homoserine/homoserine lactone efflux protein gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00610 SH03_RS00615 SH03_00615 SH03_RS00615 125441 126463 + lysophospholipase L2 lecithinase B%3B catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine%3B can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00615 SH03_RS00620 SH03_00620 SH03_RS00620 126471 127271 + pyridoxal phosphate phosphatase YigL gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00620 SH03_RS00625 SH03_00625 SH03_RS00625 127347 128246 + EamA-like transporter gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00625 SH03_RS00630 SH03_00630 SH03_RS00630 128134 129087 - transcriptional regulator homocysteine-binding%3B positive regulator of metA%2C metE and metH gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00630 SH03_RS00635 SH03_00635 SH03_RS00635 129324 131585 + 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00635 SH03_RS00640 SH03_00640 SH03_RS00640 131625 132440 - carboxymethylenebutenolidase gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00640 SH03_RS00645 SH03_00645 SH03_RS00645 132702 133463 + uridine phosphorylase catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate%3B involved in the pyrimidine salvage pathway gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00645 SH03_RS00650 SH03_00650 SH03_RS00650 133604 135031 + DNA recombination protein RmuC YigN%3B nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence%3B transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00650 SH03_RS00655 SH03_00655 ubiE ubiE 135126 135881 + ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone and menaquinone gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00655 SH03_RS00660 SH03_00660 SH03_RS00660 135895 136500 + ubiquinone biosynthesis protein UbiJ gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00660 SH03_RS00665 SH03_00665 ubiB ubiB 136497 138137 + hypothetical protein an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone%3B functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis%3B similar to eukaryotic proteins that exhibit kinase functions gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00665 SH03_RS00670 SH03_00670 tatA tatA 138216 138485 + protein translocase TatA TatA%3B similar to TatE that is found in some proteobacteria%3B part of system that translocates proteins with a conserved twin arginine motif across the inner membrane%3B capable of translocating folded substrates typically those with bound cofactors%3B similar to a protein import system in thylakoid membranes gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00670 SH03_RS00675 SH03_00675 SH03_RS00675 138489 139004 + Sec-independent protein translocase TatB mediates the export of protein precursors bearing twin-arginine signal peptides gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00675 SH03_RS00680 SH03_00680 SH03_RS00680 139007 139783 + preprotein translocase subunit TatC with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00680 SH03_RS00685 SH03_00685 SH03_RS00685 139825 140607 + Tat-linked quality control protein TatD magnesium dependent%3B involved in quality control of mutated Tat exported substrates%3B not involved in the Sec-independent protein export system gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00685 SH03_RS00690 SH03_00690 rfaH rfaH 140604 141092 - transcription antitermination protein RfaH gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00690 SH03_RS00695 SH03_00695 SH03_RS00695 141259 142752 + 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00695 SH03_RS00700 SH03_00700 fre fre 142798 143499 + NAD(P)H-flavin reductase NAD(P)H-flavin reductase%3B catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide%3B in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00700 SH03_RS00705 SH03_00705 fadA fadA 143880 145043 - 3-ketoacyl-CoA thiolase FadA%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadB%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00705 SH03_RS00710 SH03_00710 fadB fadB 145053 147242 - fatty acid oxidation complex subunit alpha includes enoyl-CoA hydratase%2C delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase%2C 3-hydroxyacyl-CoA dehydrogenase%2C and 3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities%3B forms a heterotetramer with FadA%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00710 SH03_RS00715 SH03_00715 SH03_RS00715 147432 148763 + Xaa-Pro dipeptidase catalyzes the hydrolysis of dipeptides with a proline at the C-terminal%3B also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00715 SH03_RS00720 SH03_00720 SH03_RS00720 148763 149377 + IMPACT family member YigZ gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00720 SH03_RS00725 SH03_00725 SH03_RS00725 149416 150867 + trk system potassium uptake protein trkH gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00725 SH03_RS00730 SH03_00730 hemG hemG 150879 151424 + protoporphyrinogen IX dehydrogenase [menaquinone] catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00730 SH03_RS00735 SH03_00735 SH03_RS00735 151800 153355 + 16S ribosomal RNA rRNA gene146 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00735 SH03_RS00740 SH03_00740 SH03_RS00740 153412 153488 + tRNA-Ile tRNA gene147 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00740 SH03_RS00745 SH03_00745 SH03_RS00745 153531 153606 + tRNA-Ala tRNA gene148 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00745 SH03_RS00750 SH03_00750 SH03_RS00750 153781 156712 + 23S ribosomal RNA rRNA gene149 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00750 SH03_RS00755 SH03_00755 SH03_RS00755 156790 156905 + 5S ribosomal RNA rRNA gene150 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00755 SH03_RS00760 SH03_00760 SH03_RS00760 157177 157704 - molybdopterin-guanine dinucleotide biosynthesis adapter protein in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00760 SH03_RS00765 SH03_00765 mobA mobA 157686 158270 - molybdenum cofactor guanylyltransferase in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00765 SH03_RS00770 SH03_00770 SH03_RS00770 158340 158609 + hypothetical protein gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00770 SH03_RS00775 SH03_00775 SH03_RS00775 158686 159672 + protein RdoA catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro%3B specific substrate in vivo has not been identified yet%3B plays a role in long-term cell survival and expression of surface appendages gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00775 SH03_RS00780 SH03_00780 SH03_RS00780 159689 160315 + thiol:disulfide interchange protein DsbA gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00780 SH03_RS00785 SH03_00785 SH03_RS00785 160470 161900 + DUF945 domain-containing protein gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00785 SH03_RS00790 SH03_00790 SH03_RS00790 161941 162873 - acyltransferase gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00790 SH03_RS00795 SH03_00795 SH03_RS00795 162993 163235 - hypothetical protein gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00795 SH03_RS00800 SH03_00800 SH03_RS00800 163237 166023 + DNA polymerase I gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00800 SH03_RS00805 SH03_00805 SH03_RS00805 166404 167036 - GTP-binding protein gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00805 SH03_RS00810 SH03_00810 SH03_RS00810 167618 168127 + der GTPase-activating protein YihI gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00810 SH03_RS00815 SH03_00815 SH03_RS00815 168316 169689 + coproporphyrinogen III oxidase catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00815 SH03_RS00820 SH03_00820 SH03_RS00820 169918 170028 - hypothetical protein gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00820 SH03_RS00825 SH03_00825 glnG glnG 170140 171549 - nitrogen regulation protein NR(I) response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes%3B interacts with sigma-54 gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00825 SH03_RS00830 SH03_00830 glnL glnL 171561 172610 - PAS domain-containing two-component system sensor histidine kinase sensory histidine kinase in two-component regulatory system with GlnG%3B acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00830 SH03_RS00835 SH03_00835 glnA glnA 172896 174305 - glutamine synthetase forms a homododecamer%3B forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate%3B also functions in the assimilation of ammonia%3B highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues%3B addition of adenylyl groups results in inactivation of the enzyme gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00835 SH03_RS00840 SH03_00840 SH03_RS00840 174284 174517 - hypothetical protein gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00840 SH03_RS00845 SH03_00845 SH03_RS00845 174678 176501 + GTP-binding protein gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00845 SH03_RS00850 SH03_00850 SH03_RS00850 176718 177428 + transcriptional regulator gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00850 SH03_RS00855 SH03_00855 SH03_RS00855 177436 178416 + sugar phosphate isomerase gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00855 SH03_RS00860 SH03_00860 SH03_RS00860 178518 179783 + hypothetical protein gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00860 SH03_RS00865 SH03_00865 ompL ompL 179874 180566 - porin porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall%3B specific substrate still unknown gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00865 SH03_RS00870 SH03_00870 SH03_RS00870 180634 182037 - sulfoquinovose importer gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00870 SH03_RS00875 SH03_00875 SH03_RS00875 182080 183465 - 2%2C3-dihydroxypropane-1-sulfonate exporter gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00875 SH03_RS00880 SH03_00880 SH03_RS00880 183511 185547 - alpha-glucosidase YihQ gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00880 SH03_RS00885 SH03_00885 SH03_RS00885 185746 186648 - aldose-1-epimerase gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00885 SH03_RS00890 SH03_00890 SH03_RS00890 186786 188027 - sulfoquinovose isomerase gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00890 SH03_RS00895 SH03_00895 SH03_RS00895 188044 188922 - sulfofructosephosphate aldolase gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00895 SH03_RS00900 SH03_00900 SH03_RS00900 188946 189842 - 3-sulfolactaldehyde reductase catalyzes the formation of gamma hydroxybutyrate from succinate semialdehyde gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00900 SH03_RS00905 SH03_00905 SH03_RS00905 190010 190906 + sulfofructose kinase gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00905 SH03_RS00910 SH03_00910 SH03_RS00910 190940 191725 + DeoR family transcriptional regulator gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00910 SH03_RS00915 SH03_00915 SH03_RS00915 191824 192423 + alpha-D-glucose-1-phosphate phosphatase YihX gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00915 SH03_RS00920 SH03_00920 SH03_RS00920 192417 193289 + membrane protein gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00920 SH03_RS00925 SH03_00925 SH03_RS00925 193286 193723 + D-aminoacyl-tRNA deacylase hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr)%3B possible defense mechanism against a harmful effect of D-tyrosine gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00925 SH03_RS00930 SH03_00930 SH03_RS00930 193768 194709 + hypothetical protein gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00930 SH03_RS00935 SH03_00935 SH03_RS00935 195562 195780 + hypothetical protein gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00935 SH03_RS00940 SH03_00940 SH03_RS00940 195998 196240 + hypothetical protein gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00940 SH03_RS00945 SH03_00945 SH03_RS00945 196256 196405 - hypothetical protein gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00945 SH03_RS00950 SH03_00950 SH03_RS00950 196570 197499 - protein FdhE required for the formation of active formate dehydrogenase gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00950 SH03_RS00955 SH03_00955 SH03_RS00955 197496 198131 - formate dehydrogenase cytochrome b556(fdo) subunit cytochrome b556(FDO) component%3B heme containing gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00955 SH03_RS00960 SH03_00960 SH03_RS00960 198128 199030 - formate dehydrogenase-O iron-sulfur subunit beta subunit%3B involved in the use of formate as an electron donor during aerobic respiration%3B acts to transfer electrons from the major(alpha subunit) to the cytochrome b556(gamma subunit) gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00960 SH03_RS00965 SH03_00965 SH03_RS00965 199043 201457 - formate dehydrogenase subunit alpha gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00965 SH03_RS00970 SH03_00970 SH03_RS00970 201506 202093 - sulfate ABC transporter substrate-binding protein gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00970 SH03_RS00975 SH03_00975 SH03_RS00975 202287 203120 + protein FdhD involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00975 SH03_RS00980 SH03_00980 SH03_RS00980 203273 204328 + DUF3829 domain-containing protein gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00980 SH03_RS00985 SH03_00985 SH03_RS00985 204378 206126 - frv operon regulator%3B contains a PTS EIIA domain repressor of the frv operon%2C involved in phosphoenolpyruvate:sugar phosphotransferase system gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00985 SH03_RS00990 SH03_00990 SH03_RS00990 206126 207196 - peptidase gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00990 SH03_RS00995 SH03_00995 SH03_RS00995 207186 208637 - fructose-like PTS system EIIBC component gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS00995 SH03_RS01000 SH03_01000 SH03_RS01000 208648 209094 - fructose-like phosphotransferase enzyme IIA component with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars%3B possibly responsible for the sugar specificity of the system gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01000 SH03_RS01005 SH03_01005 SH03_RS01005 209395 209709 - L-rhamnose mutarotase gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01005 SH03_RS01010 SH03_01010 SH03_RS01010 209719 210543 - rhamnulose-1-phosphate aldolase gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01010 SH03_RS01015 SH03_01015 SH03_RS01015 210994 212253 - L-rhamnose isomerase catalyzes the formation of L-rhamnulose from L-rhamnose gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01015 SH03_RS01020 SH03_01020 rhaB rhaB 212250 213719 - rhamnulokinase catalyzes the ATP-dependent phosphorylation of rhamnulose gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01020 SH03_RS01025 SH03_01025 SH03_RS01025 213798 213947 + hypothetical protein gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01025 SH03_RS01030 SH03_01030 SH03_RS01030 214007 214843 + transcriptional activator RhaS gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01030 SH03_RS01035 SH03_01035 SH03_RS01035 214917 215765 + HTH-type transcriptional activator RhaR activates the expression of rhaRS in response to L-rhamnose gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01035 SH03_RS01040 SH03_01040 SH03_RS01040 215762 216796 - l-rhamnose-proton symporter transports L-rhamnose and L-lyxose into the cell gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01040 SH03_RS01045 SH03_01045 SH03_RS01045 217081 217701 + superoxide dismutase [Mn] SodA%3B manganese binding%3B only present under aerobic conditions%3B destroys free radicals gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01045 SH03_RS01050 SH03_01050 SH03_RS01050 217742 217858 - hypothetical protein gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01050 SH03_RS01055 SH03_01055 SH03_RS01055 217961 218944 + 2-keto-3-deoxygluconate permease transports degraded pectin products into the bacterial cell gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01055 SH03_RS01060 SH03_01060 SH03_RS01060 219093 219767 + hypothetical protein gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01060 SH03_RS01065 SH03_01065 cpxA cpxA 219873 221246 - two-component system sensor histidine kinase part of two-component CpxA/CpxR system%3B senses envelope stress%3B upregulates a number of periplasmic folding and trafficking factors gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01065 SH03_RS01070 SH03_01070 SH03_RS01070 221243 221941 - two-component system response regulator response regulator in two-component regulatory system with CpxA%3B part of the envelope stress response system gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01070 SH03_RS01075 SH03_01075 cpxP cpxP 222091 222591 + periplasmic protein CpxP repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA%3B CpxP is degraded by DegP protease especially in the presence of misfolded substrates gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01075 SH03_RS01080 SH03_01080 fieF fieF 222740 223642 + ferrous iron and zinc transporter member of cation diffusion facilitator family%3B CDF%3B membrane-bound%3B induced by both zinc and iron%2C but does not induce resistance to zinc%3B can transport zinc(II) in a proton-dependent manner%3B instead this protein induces iron resistance%3B forms dimers gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01080 SH03_RS01085 SH03_01085 SH03_RS01085 223823 224785 + ATP-dependent 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01085 SH03_RS01090 SH03_01090 SH03_RS01090 225105 226094 + sulfate-binding protein gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01090 SH03_RS01095 SH03_01095 SH03_RS01095 226201 226956 + CDP-diacylglycerol pyrophosphatase gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01095 SH03_RS01100 SH03_01100 SH03_RS01100 227011 227778 - triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01100 SH03_RS01105 SH03_01105 SH03_RS01105 227886 228485 - DUF1454 domain-containing protein gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01105 SH03_RS01110 SH03_01110 SH03_RS01110 228586 229026 + membrane protein gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01110 SH03_RS01115 SH03_01115 SH03_RS01115 229238 229537 + hypothetical protein gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01115 SH03_RS01120 SH03_01120 SH03_RS01120 229564 229992 + universal stress protein D with UspC and Usp E is involved in resistance to UV radiation gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01120 SH03_RS01125 SH03_01125 SH03_RS01125 229997 230743 - ferredoxin--NADP reductase gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01125 SH03_RS01130 SH03_01130 SH03_RS01130 230840 231850 - fructose 1%2C6-bisphosphatase gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01130 SH03_RS01135 SH03_01135 glpK glpK 231985 233493 - glycerol kinase Converts glycerol and ADP to glycerol-3-phosphate and ADP gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01135 SH03_RS01140 SH03_01140 SH03_RS01140 233516 234361 - glycerol uptake facilitator protein involved in the transport of glycerol into the cell gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01140 SH03_RS01145 SH03_01145 SH03_RS01145 234792 235031 + cell division protein ZapB interacts with FisZ and is necessary for Z-ring formation gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01145 SH03_RS01150 SH03_01150 SH03_RS01150 235116 235601 - ribonuclease E activity regulator RraA regulator of RNase E%3B increases half-life and abundance of RNAs%3B interacts with RNase E possibly inhibiting catalytic activity gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01150 SH03_RS01155 SH03_01155 SH03_RS01155 235694 236620 - 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase catalyzes the formation of dimethylmenaquinone from 1%2C4-dihydroxy-2-naphthoate and octaprenyl diphosphate gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01155 SH03_RS01160 SH03_01160 hslU hslU 236687 238018 - ATP-dependent protease ATPase subunit HslU heat shock protein involved in degradation of misfolded proteins gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01160 SH03_RS01165 SH03_01165 SH03_RS01165 238028 238558 - ATP-dependent protease subunit HslV gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01165 SH03_RS01170 SH03_01170 SH03_RS01170 238651 239505 - cell division protein FtsN gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01170 SH03_RS01175 SH03_01175 SH03_RS01175 239702 240727 - transcriptional regulator negatively controls the transcription initiation of genes such as deoCABD%2C udp%2C and cdd encoding catabolizing enzymes and nupC%2C nupG%2C and tsx encoding transporting and pore-forming proteins gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01175 SH03_RS01180 SH03_01180 SH03_RS01180 240883 243081 - primosomal protein N' binding of PriA to forked DNA starts the assembly of the primosome%2C also possesses 3'-5' helicase activity gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01180 SH03_RS01185 SH03_01185 rpmE rpmE 243284 243496 + 50S ribosomal protein L31 RpmE%3B there appears to be two types of ribosomal proteins L31 in bacterial genomes%3B some contain a CxxC motif while others do not%3B Bacillus subtilis has both types%3B the proteins in this cluster have the CXXC motif%3B RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth%3B expression of ytiA is controlled by a zinc-specific transcriptional repressor%3B RpmE contains one zinc ion and a CxxC motif is responsible for this binding%3B forms an RNP particle along with proteins L5%2C L18%2C and L25 and 5S rRNA%3B found crosslinked to L2 and L25 and EF-G%3B may be near the peptidyltransferase site of the 50S ribosome gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01185 SH03_RS01190 SH03_01190 SH03_RS01190 243557 244165 - lipid binding hydrolase DUF830 family protein gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01190 SH03_RS01195 SH03_01195 SH03_RS01195 244349 244666 - met repressor when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01195 SH03_RS01200 SH03_RS01200 SH03_RS01200 244943 246101 + cystathionine gamma-synthase catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01200 SH03_RS01205 SH03_01205 metL metL 246104 248536 + bifunctional aspartokinase/homoserine dehydrogenase 2 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01205 SH03_RS01210 SH03_01210 SH03_RS01210 248675 248809 - hypothetical protein gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01210 SH03_RS01215 SH03_01215 metF metF 248885 249775 + 5%2C10-methylenetetrahydrofolate reductase MTHFR%3B catalyzes NADH-linked reduction of 5%2C10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01215 SH03_RS01220 SH03_01220 SH03_RS01220 250104 252284 + catalase-peroxidase gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01220 SH03_RS01225 SH03_01225 SH03_RS01225 252377 253282 + permease gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01225 SH03_RS01230 SH03_01230 SH03_RS01230 253309 253926 - DUF1287 domain-containing protein gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01230 SH03_RS01235 SH03_01235 SH03_RS01235 254038 254157 - hypothetical protein gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01235 SH03_RS01240 SH03_01240 gldA gldA 254201 255304 - glycerol dehydrogenase forms dimers and octamers%3B involved in conversion of glycerol to dihydroxy-acetone gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01240 SH03_RS01245 SH03_01245 SH03_RS01245 255315 255977 - fructose-6-phosphate aldolase 2 similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01245 SH03_RS01250 SH03_01250 SH03_RS01250 255989 258490 - multiphosphoryl transfer protein 2 Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein HPr%3B HPr transfers the phosphoryl group to subunit A%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01250 SH03_RS01255 SH03_01255 SH03_RS01255 258799 259878 + fructose-like permease IIC component 2 gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01255 SH03_RS01260 SH03_01260 SH03_RS01260 259893 260213 + fructose-like phosphotransferase enzyme IIB component 2 FrwB with FrwC%2C FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell%3B cytoplasmic protein that interacts with complex EIIA%3B contains the second phosphorylation site of the PTS gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01260 SH03_RS01265 SH03_01265 pflD pflD 260264 262561 + formate acetyltransferase 2 involved in production of D-lactate from glucose under microaerobic conditions%3B cytoplasmic protein gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01265 SH03_RS01270 SH03_01270 SH03_RS01270 262527 263405 + pyruvate formate-lyase 2-activating enzyme gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01270 SH03_RS01275 SH03_01275 SH03_RS01275 263407 263748 + fructose-like phosphotransferase enzyme IIB component 3 FrwD with FrwB%2C FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell%3B phosphorylated by EIIA%3B FrwB homolog gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01275 SH03_RS01280 SH03_01280 SH03_RS01280 263735 264586 - AraC family transcriptional regulator gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01280 SH03_RS01285 SH03_01285 SH03_RS01285 264801 266534 - phosphoethanolamine transferase EptC gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01285 SH03_RS01290 SH03_01290 SH03_RS01290 266716 269367 - phosphoenolpyruvate carboxylase catalyzes the formation of oxaloacetate from phosphoenolpyruvate gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01290 SH03_RS01295 SH03_01295 SH03_RS01295 269585 269977 - hypothetical protein gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01295 SH03_RS01300 SH03_01300 SH03_RS01300 269965 271116 - acetylornithine deacetylase catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01300 SH03_RS01305 SH03_01305 SH03_RS01305 271270 272274 + N-acetyl-gamma-glutamyl-phosphate reductase gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01305 SH03_RS01310 SH03_01310 SH03_RS01310 272285 273058 + acetylglutamate kinase gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01310 SH03_RS01315 SH03_01315 SH03_RS01315 273119 274492 + argininosuccinate lyase catalyzes the formation of arginine from (N-L-arginino)succinate gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01315 SH03_RS01320 SH03_01320 SH03_RS01320 274759 275676 + hydrogen peroxide-inducible genes activator Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG%2C gor%2C ahpC%2C ahpF%2C oxyS%2C dps%2C fur and grxA gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01320 SH03_RS01325 SH03_01325 SH03_RS01325 275659 277059 - soluble pyridine nucleotide transhydrogenase catalyzes the conversion of NADPH to NADH gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01325 SH03_RS01330 SH03_01330 SH03_RS01330 277393 278040 + transcriptional regulator negatively controls the expression of fabA and fabB%2C genes involved in the unsaturated fatty acid biosynthesis gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01330 SH03_RS01335 SH03_01335 SH03_RS01335 278040 278399 + hypothetical protein gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01335 SH03_RS01340 SH03_01340 SH03_RS01340 278439 279539 - tRNA/tmRNA (uracil-C(5))-methyltransferase catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01340 SH03_RS01345 SH03_01345 btuB btuB 279908 281752 + vitamin B12 transporter BtuB involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01345 SH03_RS01350 SH03_01350 SH03_RS01350 281766 282554 + glutamate racemase converts L-glutamate to D-glutamate%2C a component of peptidoglycan gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01350 SH03_RS01355 SH03_01355 SH03_RS01355 282926 284481 + 16S ribosomal RNA rRNA gene270 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01355 SH03_RS01360 SH03_01360 SH03_RS01360 284555 284630 + tRNA-Glu tRNA gene271 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01360 SH03_RS01365 SH03_01365 SH03_RS01365 284815 287742 + 23S ribosomal RNA rRNA gene272 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01365 SH03_RS01370 SH03_01370 SH03_RS01370 287820 287935 + 5S ribosomal RNA rRNA gene273 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01370 SH03_RS01375 SH03_01375 murB murB 288238 289266 + UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01375 SH03_RS01380 SH03_01380 SH03_RS01380 289263 290228 + bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor catalyzes the formation of biotinyl-5'-AMP%2C also acts as a transcriptional repressor of the biotin operon gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01380 SH03_RS01385 SH03_01385 SH03_RS01385 290257 291213 - type I pantothenate kinase gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01385 SH03_RS01390 SH03_01390 SH03_RS01390 291394 291549 - hypothetical protein gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01390 SH03_RS01395 SH03_01395 SH03_RS01395 291569 291644 + tRNA-Thr tRNA gene278 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01395 SH03_RS01400 SH03_01400 SH03_RS01400 291653 291737 + tRNA-Tyr tRNA gene279 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01400 SH03_RS01405 SH03_01405 SH03_RS01405 291854 291928 + tRNA-Gly tRNA gene280 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01405 SH03_RS01410 SH03_01410 SH03_RS01410 291935 292010 + tRNA-Thr tRNA gene281 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01410 SH03_RS01415 SH03_01415 tuf tuf 292125 293309 + translation elongation factor EF-Tu 2 EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01415 SH03_RS01420 SH03_01420 secE secE 293539 293922 + protein translocase subunit SecE forms a complex with SecY and SecG%3B SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane%2C a process driven by ATP and a proton-motive force gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01420 SH03_RS01425 SH03_01425 nusG nusG 293924 294469 + transcription termination/antitermination protein NusG Modulates Rho-dependent transcription termination gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01425 SH03_RS01430 SH03_01430 SH03_RS01430 294628 295056 + 50S ribosomal protein L11 gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01430 SH03_RS01435 SH03_01435 SH03_RS01435 295060 295764 + 50S ribosomal protein L1 gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01435 SH03_RS01440 SH03_01440 rplJ rplJ 296177 296674 + 50S ribosomal protein L10 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01440 SH03_RS01445 SH03_01445 rplL rplL 296741 297106 + 50S ribosomal protein L7/L12 present in two forms%3B L12 is normal%2C while L7 is aminoacylated at the N-terminal serine%3B the only multicopy ribosomal protein%3B 4:1 ratio of L7/L12 per ribosome%3B two L12 dimers bind L10%3B critically important for translation efficiency and fidelity%3B stimulates GTPase activity of translation factors gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01445 SH03_RS01450 SH03_01450 rpoB rpoB 297426 301454 + DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01450 SH03_RS01455 SH03_01455 SH03_RS01455 301531 305754 + DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01455 SH03_RS01460 SH03_01460 SH03_RS01460 305967 306506 + heat-shock protein C gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01460 SH03_RS01465 SH03_01465 thiH thiH 306916 308049 - 2-iminoacetate synthase in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS%3B with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine%2C cysteine and 1-deoxy-D-xylulose-5-phosphate%3B forms a complex with ThiG%3B contains an iron-sulfur center gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01465 SH03_RS01470 SH03_01470 SH03_RS01470 308046 308816 - thiazole synthase gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01470 SH03_RS01475 SH03_01475 SH03_RS01475 308818 309018 - thiamine biosynthesis protein ThiS with ThiF%2C ThiG%2C and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01475 SH03_RS01480 SH03_01480 SH03_RS01480 309002 309757 - thiamine biosynthesis protein ThiS ATP-dependent adenylate transferase%2C transfers adenyl moiety to the MoeD subunit of molybdopterin synthase gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01480 SH03_RS01485 SH03_01485 SH03_RS01485 309750 310385 - thiamine-phosphate synthase catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01485 SH03_RS01490 SH03_01490 SH03_RS01490 310385 312280 - phosphomethylpyrimidine synthase catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01490 SH03_RS01495 SH03_01495 SH03_RS01495 312513 312989 - regulator of sigma D binds specifically to the major sigma factor sigma 70%3B active in stationary phase gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01495 SH03_RS01500 SH03_01500 nudC nudC 313084 313857 + NADH pyrophosphatase can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH%3B requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01500 SH03_RS01505 SH03_01505 hemE hemE 313897 314961 + uroporphyrinogen decarboxylase catalyzes the formation of coproporphyrinogen from uroporphyrinogen III gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01505 SH03_RS01510 SH03_01510 SH03_RS01510 314971 315642 + endonuclease V Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B cleaves DNA containing urea residues%2C AP sites%2C base mismatches%2C insertion/deletion mismatches%2C flaps%2C and pseudo-Y structures gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01510 SH03_RS01515 SH03_01515 SH03_RS01515 315685 316275 + hypothetical protein gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01515 SH03_RS01520 SH03_01520 SH03_RS01520 316462 316734 + DNA-binding protein HU-alpha gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01520 SH03_RS01525 SH03_01525 SH03_RS01525 316747 317442 + DUF1481 domain-containing protein gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01525 SH03_RS01530 SH03_01530 zraP zraP 317444 317869 - zinc resistance-associated protein gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01530 SH03_RS01535 SH03_01535 SH03_RS01535 318107 319504 + two-component system sensor histidine kinase gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01535 SH03_RS01540 SH03_01540 SH03_RS01540 319501 320826 + ZraR family transcriptional regulator DNA-binding response regulator in two-component regulatory system with ZraS%3B response regulator/sigma54 interaction protein gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01540 SH03_RS01545 SH03_01545 SH03_RS01545 320823 322112 - phosphoribosylamine--glycine ligase catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01545 SH03_RS01550 SH03_01550 purH purH 322124 323713 - bifunctional purine biosynthesis protein PurH involved in de novo purine biosynthesis gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01550 SH03_RS01555 SH03_RS01555 SH03_RS01555 323667 323852 - hypothetical protein gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01555 SH03_RS01560 SH03_RS01560 SH03_RS01560 323786 323989 - hypothetical protein gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01560 SH03_RS01565 SH03_01555 SH03_RS01565 324326 325881 + 16S ribosomal RNA rRNA gene312 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01565 SH03_RS01570 SH03_01560 SH03_RS01570 325955 326030 + tRNA-Glu tRNA gene313 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01570 SH03_RS01575 SH03_01565 SH03_RS01575 326215 329145 + 23S ribosomal RNA rRNA gene314 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01575 SH03_RS01580 SH03_01570 SH03_RS01580 329223 329338 + 5S ribosomal RNA rRNA gene315 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01580 SH03_RS01585 SH03_01575 SH03_RS01585 329415 329798 + stress-induced protein gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01585 SH03_RS01590 SH03_01580 SH03_RS01590 329861 330304 - GNAT family acetyltransferase gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01590 SH03_RS01595 SH03_01585 SH03_RS01595 330461 331390 + homoserine O-succinyltransferase catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01595 SH03_RS01600 SH03_01590 SH03_RS01600 331659 333260 + malate synthase A Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01600 SH03_RS01605 SH03_01595 SH03_RS01605 333290 334594 + isocitrate lyase gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01605 SH03_RS01610 SH03_01600 aceK aceK 334777 336513 + isocitrate dehydrogenase catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity%3B unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01610 SH03_RS01615 SH03_01605 SH03_RS01615 336482 338668 - ankyrin repeat protein A gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01615 SH03_RS01620 SH03_01610 SH03_RS01620 338985 339809 - acetate operon repressor regulates the glyoxylate bypass operon (aceBAK)%2C which encodes isocitrate lyase%2C malate synthase and isocitrate dehydrogenase kinase/phosphorylase gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01620 SH03_RS01625 SH03_01615 metH metH 340009 343692 + methionine synthase one of two methionine synthases in Escherichia coli%3B MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine%3B requires zinc for activity gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01625 SH03_RS01630 SH03_01620 SH03_RS01630 343912 345543 + transporter gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01630 SH03_RS01635 SH03_01625 SH03_RS01635 345634 346323 - peptidase E peptidase E%3B catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue%3B belongs to peptidase S51 family gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01635 SH03_RS01640 SH03_01630 SH03_RS01640 346535 347407 + ribosomal large subunit pseudouridine synthase F catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01640 SH03_RS01645 SH03_01635 SH03_RS01645 347540 347812 - DUF3811 domain-containing protein gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01645 SH03_RS01650 SH03_01640 SH03_RS01650 348065 349414 - lysine-sensitive aspartokinase 3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP%3B functions in amino acid biosynthesis%3B lysine sensitive gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01650 SH03_RS01655 SH03_01645 pgi pgi 349939 351588 + glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01655 SH03_RS01660 SH03_01650 SH03_RS01660 351711 352214 - transposase gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01660 SH03_RS01665 SH03_01655 SH03_RS01665 352133 352408 - repressor TnpA gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01665 SH03_RS01670 SH03_01660 SH03_RS01670 352864 353106 + polysaccharide production threonine-rich protein gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01670 SH03_RS01675 SH03_01665 SH03_RS01675 353220 353858 + polysaccharide production lipoprotein gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01675 SH03_RS01680 SH03_01670 SH03_RS01680 353855 354592 + polysaccharide export OMA protein gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01680 SH03_RS01685 SH03_01675 SH03_RS01685 354592 356688 + DUF940 domain-containing protein gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01685 SH03_RS01690 SH03_01680 SH03_RS01690 356735 357013 - periplasmic protein gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01690 SH03_RS01695 SH03_01685 SH03_RS01695 357014 357157 + hypothetical protein gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01695 SH03_RS01700 SH03_01695 SH03_RS01700 357283 357693 + protein PsiE gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01700 SH03_RS01705 SH03_01700 xylE xylE 357737 359212 - D-xylose-proton symporter xylose/proton symporter%3B member of the major facilitator superfamily (MFS) of transporter gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01705 SH03_RS01710 SH03_01705 malG malG 359584 360474 - maltose ABC transporter permease with MalKFE is involved in the transport of maltose into the cell gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01710 SH03_RS01715 SH03_01710 malF malF 360489 362033 - maltose ABC transporter permease with MalKGE is involved in maltose transport into the cell gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01715 SH03_RS01720 SH03_01715 malE malE 362187 363377 - maltose-binding periplasmic protein functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01720 SH03_RS01725 SH03_01720 SH03_RS01725 363470 363565 - sugar ABC transporter gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01725 SH03_RS01730 SH03_01725 SH03_RS01730 363742 364857 + maltose/maltodextrin import ATP-binding protein MalK with malEFG is involved in import of maltose/maltodextrin gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01730 SH03_RS01735 SH03_01730 lamB lamB 364929 366269 + maltoporin porin involved in the transport of maltose and maltodextrins gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01735 SH03_RS01740 SH03_01735 SH03_RS01740 366512 367432 + maltose operon periplasmic protein gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01740 SH03_RS01745 SH03_01740 SH03_RS01745 367661 367855 + hypothetical protein gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01745 SH03_RS01750 SH03_01745 SH03_RS01750 367913 369241 + hypothetical protein in E. coli%2C some yjbl mutations have been reported as suppressors of dnaG mutations gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01750 SH03_RS01755 SH03_01750 ubiC ubiC 369464 369961 + Chorismate pyruvate-lyase catalyzes the formation of 4-hydroxybenzoate from chorismate gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01755 SH03_RS01760 SH03_01755 ubiA ubiA 369974 370846 + 4-hydroxybenzoate octaprenyltransferase catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate%2C as part of the ubiquinone biosynthesis pathway gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01760 SH03_RS01765 SH03_01760 SH03_RS01765 371001 373424 - glycerol-3-phosphate acyltransferase PlsB%3B catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01765 SH03_RS01770 SH03_01765 SH03_RS01770 373595 373963 + diacylglycerol kinase catalyzes the phosphorylation of diacylglycerol to form diacylglycerol phosphate gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01770 SH03_RS01775 SH03_01770 SH03_RS01775 374073 374681 + LexA repressor Represses a number of genes involved in the response to DNA damage gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01775 SH03_RS01780 SH03_01775 SH03_RS01780 374754 376079 + MATE family efflux transporter gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01780 SH03_RS01785 SH03_01780 SH03_RS01785 376195 376404 + stress-induced protein%2C UPF0337 family gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01785 SH03_RS01790 SH03_01785 SH03_RS01790 376446 376961 - zinc uptake regulation protein Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01790 SH03_RS01795 SH03_01790 SH03_RS01795 377279 377533 + hypothetical protein gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01795 SH03_RS01800 SH03_01795 SH03_RS01800 377557 378264 + hypothetical protein gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01800 SH03_RS01805 SH03_01800 SH03_RS01805 378672 379664 + tRNA-dihydrouridine synthase A gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01805 SH03_RS01810 SH03_01805 pspG pspG 379798 380040 + phage shock protein G coordinately regulated along with pspA%3B PspF-dependent induction in response to secretin overexpression in Yersinia gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01810 SH03_RS01815 SH03_01810 SH03_RS01815 380206 381189 - quinone oxidoreductase 1 gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01815 SH03_RS01820 SH03_01815 SH03_RS01820 381272 382687 + replicative DNA helicase unwinds double stranded DNA gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01820 SH03_RS01825 SH03_01820 alr alr 382740 383819 + alanine racemase biosynthetic converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01825 SH03_RS01830 SH03_01825 SH03_RS01830 384072 385265 + aromatic-amino-acid aminotransferase catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01830 SH03_RS01835 SH03_RS01835 SH03_RS01835 385487 385970 - hypothetical protein gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01835 SH03_RS01840 SH03_01835 aphA aphA 386372 387085 + class B acid phosphatase Class B%3B non-specific%3B catalyzes the dephosphorylation of organic phosphomonoesters%3B also has phosphotransferase activity gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01840 SH03_RS01845 SH03_01840 SH03_RS01845 387196 387612 + thiamin phosphate synthase gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01845 SH03_RS01850 SH03_01845 SH03_RS01850 387616 387972 + hypothetical protein gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01850 SH03_RS01855 SH03_01850 SH03_RS01855 388007 390829 - UvrABC system protein A gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01855 SH03_RS01860 SH03_01855 SH03_RS01860 391083 391619 + single-stranded DNA-binding protein binds to single stranded DNA and PriA helcase facilitate replication restart gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01860 SH03_RS01865 SH03_01860 SH03_RS01865 391718 391999 - membrane protein gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01865 SH03_RS01870 SH03_01865 SH03_RS01870 392429 394015 + cyclic-di-GMP phosphodiesterase gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01870 SH03_RS01875 SH03_01870 SH03_RS01875 394018 394341 - regulatory protein SoxS regulates genes involved in response to oxidative stress gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01875 SH03_RS01880 SH03_01875 SH03_RS01880 394427 394891 + redox-sensitive transcriptional activator SoxR gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01880 SH03_RS01885 SH03_01880 SH03_RS01885 395437 396786 + guanine/hypoxanthine permease GhxP gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01885 SH03_RS01890 SH03_01885 SH03_RS01890 396938 398587 + cation/proton antiporter gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01890 SH03_RS01895 SH03_01890 SH03_RS01895 398741 400033 - hypothetical protein gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01895 SH03_RS01900 SH03_01895 actP actP 400211 401860 - cation/acetate symporter ActP member of the sodium:solute symporter family%3B cotranscribed with the acs gene which encodes acetyl coenzyme A synthase%3B mutations affect acetate uptake gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01900 SH03_RS01905 SH03_01900 SH03_RS01905 401857 402171 - hypothetical protein gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01905 SH03_RS01910 SH03_01905 SH03_RS01910 402371 404329 - acetyl-CoA synthetase Acs%3B catalyzes the conversion of acetate and CoA to acetyl-CoA gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01910 SH03_RS01915 SH03_01910 nrfA nrfA 404722 406158 + cytochrome c-552 catalyzes the formate-dependent reduction of nitrite to ammonia%3B cytochrome C552 gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01915 SH03_RS01920 SH03_01915 SH03_RS01920 406203 406769 + cytochrome c-type protein NrfB part of nitrite reductase complex%3B NrfB is active at high nitrate conditions%3B NrfA%2C B%2C C%2C and D are essential for the formate-dependent nitrite reduction to ammonia gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01920 SH03_RS01925 SH03_01920 SH03_RS01925 406766 407437 + protein NrfC 4Fe4S subunit%3B may be involved in the transfer of electrons from quinones to the c-type cytochromes gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01925 SH03_RS01930 SH03_01925 SH03_RS01930 407434 408390 + protein NrfD membrane protein%2C may be involved in the transfer of electrons from quinones to c-type cytochromes gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01930 SH03_RS01935 SH03_01930 SH03_RS01935 408521 410128 + heme lyase subunit NrfE with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01935 SH03_RS01940 SH03_01935 SH03_RS01940 410121 410504 + formate-dependent nitrite reductase complex subunit NrfF gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01940 SH03_RS01945 SH03_01940 SH03_RS01945 410501 411097 + formate-dependent nitrite reductase complex subunit NrfG gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01945 SH03_RS01950 SH03_01945 SH03_RS01950 411439 412752 + proton glutamate symport protein gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01950 SH03_RS01955 SH03_01950 SH03_RS01955 413283 413972 - hypothetical protein gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01955 SH03_RS01960 SH03_01955 SH03_RS01960 414066 415745 - formate dehydrogenase subunit alpha gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01960 SH03_RS01965 SH03_01960 SH03_RS01965 415794 416213 - spermidine/putrescine ABC transporter substrate-binding protein gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01965 SH03_RS01970 SH03_01965 SH03_RS01970 416411 417877 - multidrug resistance outer membrane protein MdtP part of a multidrug efflux system involved in resistance to acriflavin%2C puromycin%2C erytjhromycin and tetraphenylarsonium chloride%3B member of the outer membrane factor (OMF) family gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01970 SH03_RS01975 SH03_01970 SH03_RS01975 417874 419925 - multidrug resistance protein MdtO possibly part of a tripartite efflux system composed of MdtN%2C MdtO and MdtP which could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01975 SH03_RS01980 SH03_01975 SH03_RS01980 419925 420956 - multidrug resistance protein MdtN with MdtO and MdtP is involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01980 SH03_RS01985 SH03_01980 SH03_RS01985 420975 421250 - transporter gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01985 SH03_RS01990 SH03_01985 SH03_RS01990 421459 423444 - MBL fold hydrolase gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01990 SH03_RS01995 SH03_01990 SH03_RS01995 423717 424646 - D-allose kinase gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS01995 SH03_RS02000 SH03_01995 SH03_RS02000 424630 425325 - D-allulose-6-phosphate 3-epimerase gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02000 SH03_RS02005 SH03_02000 SH03_RS02005 425336 426316 - D-allose ABC transporter permease gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02005 SH03_RS02010 SH03_02005 SH03_RS02010 426295 427827 - D-allose import ATP-binding protein AlsA with AlsBC acts to import allose into the cell%3B AlsA contain 2 ATP-binding domains gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02010 SH03_RS02015 SH03_02010 SH03_RS02015 427954 428889 - D-allose-binding periplasmic protein gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02015 SH03_RS02020 SH03_02015 SH03_RS02020 428948 429838 - RpiR family transcriptional regulator involved in rpiB and als operon repression gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02020 SH03_RS02025 SH03_02020 SH03_RS02025 430197 430646 + ribose-5-phosphate isomerase B gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02025 SH03_RS02030 SH03_02025 SH03_RS02030 430715 431044 + periplasmic protein gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02030 SH03_RS02035 SH03_02030 phnP phnP 431191 431949 - phosphoribosyl 1%2C2-cyclic phosphodiesterase required for the use of phosphonates and phosphite as phosphorus sources gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02035 SH03_RS02040 SH03_02035 SH03_RS02040 431951 432385 - protein PhnO PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids%3B part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source%3B Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02040 SH03_RS02045 SH03_02040 SH03_RS02045 432372 432929 - ribose 1%2C5-bisphosphate phosphokinase PhnN gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02045 SH03_RS02050 SH03_02045 SH03_RS02050 432929 434065 - alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02050 SH03_RS02055 SH03_02050 SH03_RS02055 434062 434742 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02055 SH03_RS02060 SH03_02055 phnK phnK 434853 435611 - phosphonate C-P lyase gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02060 SH03_RS02065 SH03_02060 SH03_RS02065 435608 436453 - alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02065 SH03_RS02070 SH03_02065 SH03_RS02070 436446 437510 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI required for the use of phosphonate and phosphite gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02070 SH03_RS02075 SH03_02070 phnH phnH 437510 438094 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02075 SH03_RS02080 SH03_02075 SH03_RS02080 438091 438543 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02080 SH03_RS02085 SH03_02080 SH03_RS02085 438544 439269 - transcriptional regulator may be involved in phosphonate uptake and biodegradation gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02085 SH03_RS02090 SH03_RS02090 SH03_RS02090 439290 440077 - phosphonate ABC transporter permease gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02090 SH03_RS02095 SH03_02090 SH03_RS02095 440183 441199 - phosphonates-binding periplasmic protein with PhnCE is involved in the transport of phosphonates gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02095 SH03_RS02100 SH03_02095 SH03_RS02100 441224 442012 - phosphonates import ATP-binding protein PhnC gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02100 SH03_RS02105 SH03_02100 SH03_RS02105 442145 442588 - protein PhnB gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02105 SH03_RS02110 SH03_02105 SH03_RS02110 443246 443581 - protein PhnA gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02110 SH03_RS02115 SH03_02110 SH03_RS02115 443982 446210 + clamp-binding protein CrfC gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02115 SH03_RS02120 SH03_02115 SH03_RS02120 446207 447085 + YjcZ family protein%3B yhjH motility defect suppressor gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02120 SH03_RS02125 SH03_02120 SH03_RS02125 447349 448851 + proline/betaine transporter gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02125 SH03_RS02130 SH03_02125 SH03_RS02130 448963 449052 + membrane-bound BasS regulator gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02130 SH03_RS02135 SH03_02130 SH03_RS02135 449028 450119 - two-component system sensor histidine kinase gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02135 SH03_RS02140 SH03_02135 SH03_RS02140 450129 450797 - two-component system response regulator response regulator in two-component regulatory system with BasS gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02140 SH03_RS02145 SH03_02140 SH03_RS02145 450794 452437 - phosphoethanolamine transferase EptA gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02145 SH03_RS02150 SH03_02145 SH03_RS02150 452541 453878 - arginine/agmatine antiporter gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02150 SH03_RS02155 SH03_02150 SH03_RS02155 454015 454776 - transcriptional regulator regulates genes involved in arginine decarboxylase gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02155 SH03_RS02160 SH03_02155 SH03_RS02160 455101 457371 - arginine decarboxylase biodegradative%3B catalyzes the formation of agmatine from arginine gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02160 SH03_RS02165 SH03_02160 SH03_RS02165 457567 458475 - melibiose operon regulatory protein gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02165 SH03_RS02170 SH03_02165 SH03_RS02170 458507 458668 + hypothetical protein gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02170 SH03_RS02175 SH03_02170 SH03_RS02175 458758 460113 + alpha-galactosidase catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02175 SH03_RS02180 SH03_02175 SH03_RS02180 460216 461637 + melibiose carrier protein gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02180 SH03_RS02185 SH03_02180 SH03_RS02185 461776 462405 - hypothetical protein gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02185 SH03_RS02190 SH03_02185 SH03_RS02190 462527 464173 - fumarate hydratase class I%2C anaerobic catalyzes the formation of malate from fumerate gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02190 SH03_RS02195 SH03_02190 SH03_RS02195 464251 465591 - anaerobic C4-dicarboxylate transporter DcuB functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to DcuA%3B DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate%2C malate%2C fumarate and succinate) transporters gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02195 SH03_RS02200 SH03_RS02200 SH03_RS02200 466057 466185 + glutamate decarboxylase gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02200 SH03_RS02205 SH03_02200 SH03_RS02205 466162 466881 - transcriptional regulator response regulator in two-component regulatory system with DcuS%3B phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02205 SH03_RS02210 SH03_02205 SH03_RS02210 466878 468509 - sensor histidine kinase C4-dicarboxylate-sensing histidine kinase%3B part of two-component regulatory system with DcuR%3B regulates anaerobic fumarate respiration gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02210 SH03_RS02215 SH03_02210 SH03_RS02215 468690 468920 + hypothetical protein gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02215 SH03_RS02220 SH03_02215 SH03_RS02220 468932 469204 + GNAT family acetyltransferase gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02220 SH03_RS02225 SH03_02220 SH03_RS02225 469291 469506 + hypothetical protein gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02225 SH03_RS02230 SH03_02225 SH03_RS02230 469521 469727 + hypothetical protein gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02230 SH03_RS02235 SH03_02230 SH03_RS02235 469755 469928 + toxin of GhoTS toxin-antitoxin pair%3B membrane-lytic protein%3B stimulator of persister cell formation gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02235 SH03_RS02240 SH03_02235 lysS lysS 470047 471564 - lysine--tRNA ligase heat inducible class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02240 SH03_RS02245 SH03_02240 SH03_RS02245 471801 473258 - dipeptide and tripeptide permease C gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02245 SH03_RS02250 SH03_02245 SH03_RS02250 473317 475464 - lysine decarboxylase inducible constitutive%3B catalyzes the formation of cadaverine from lysine gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02250 SH03_RS02255 SH03_02250 cadB cadB 475544 476878 - cadaverine/lysine antiporter antiporter protein responsible for lysine import and cadaverine export%3B member of the lysine-dependent acid resistance system 4 (AR4)%3B inner membrane protein gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02255 SH03_RS02260 SH03_02255 SH03_RS02260 477243 478781 - transcriptional activator CadC regulates the cadBA operon gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02260 SH03_RS02265 SH03_02260 SH03_RS02265 479398 479473 - tRNA-Phe tRNA gene452 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02265 SH03_RS02270 SH03_02265 SH03_RS02270 479580 480155 - transcriptional regulator gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02270 SH03_RS02275 SH03_02270 dipZ dipZ 480192 481889 - thiol:disulfide interchange protein DsbD two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm%3B DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02275 SH03_RS02280 SH03_02275 SH03_RS02280 481865 482203 - divalent-cation tolerance protein CutA copper binding protein required for copper tolerance%3B involved in resistance toward heavy metals gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02280 SH03_RS02285 SH03_02280 SH03_RS02285 482319 483620 - anaerobic C4-dicarboxylate transporter DcuA functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to dcuB gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02285 SH03_RS02290 SH03_02285 aspA aspA 483738 485174 - aspartate ammonia-lyase catalyzes the formation of fumarate from aspartate gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02290 SH03_RS02295 SH03_02290 fxsA fxsA 485511 485987 + suppressor of F exclusion of phage T7 F exclusion of bacteriophage T7%3B overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7%3B interacts with the F plasmid-encoded PifA protein%3B inner membrane protein gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02295 SH03_RS02300 SH03_02295 SH03_RS02300 486003 487259 - hypothetical protein uncharacterized member of the APC superfamily of amino acid transporters%3B unknown function gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02300 SH03_RS02305 SH03_02300 groES groES 487535 487828 + molecular chaperone GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02305 SH03_RS02310 SH03_02305 groEL groEL 487872 489518 + chaperonin GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02310 SH03_RS02315 SH03_02310 SH03_RS02315 489656 490009 + DUF4156 domain-containing protein gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02315 SH03_RS02320 SH03_02315 SH03_RS02320 490212 491081 - hypothetical protein gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02320 SH03_RS02325 SH03_02320 SH03_RS02325 491476 492504 - EF-P beta-lysylation protein EpmB gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02325 SH03_RS02330 SH03_02325 SH03_RS02330 492546 493112 + elongation factor P gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02330 SH03_RS02335 SH03_02330 SH03_RS02335 493164 493289 + entericidin A acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02335 SH03_RS02340 SH03_02335 SH03_RS02340 493400 493546 + entericidin B gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02340 SH03_RS02345 SH03_02340 SH03_RS02345 493722 494039 + quaternary ammonium compound-resistance protein SugE member of the SMR family of proton-dependent drug efflux transporters%3B quaternary ammonium compound efflux pump%3B confers resistance to cetylpyridinium%2C cetyldimethylethyl ammonium and cetrimide cations gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02345 SH03_RS02350 SH03_02345 SH03_RS02350 494036 494569 - hypothetical protein lipocalin%3B globomycin-sensitive outer membrane lipoprotein gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02350 SH03_RS02355 SH03_02350 SH03_RS02355 494658 495791 - BlaEC family class C beta-lactamase gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02355 SH03_RS02360 SH03_02355 SH03_RS02360 495854 496213 - fumarate reductase subunit D in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02360 SH03_RS02365 SH03_02360 SH03_RS02365 496224 496619 - fumarate reductase subunit C part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02365 SH03_RS02370 SH03_02365 SH03_RS02370 496630 497364 - fumarate reductase iron-sulfur subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02370 SH03_RS02375 SH03_02370 SH03_RS02375 497357 499165 - fumarate reductase flavoprotein subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02375 SH03_RS02380 SH03_02375 SH03_RS02380 499490 500467 + elongation factor P--(R)-beta-lysine ligase poxA%3B regulates pyruvate oxidase poxB gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02380 SH03_RS02385 SH03_02380 SH03_RS02385 500686 502188 + inner membrane transporter YjeM gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02385 SH03_RS02390 SH03_02385 SH03_RS02390 502240 502554 + hypothetical protein gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02390 SH03_RS02395 SH03_02390 SH03_RS02395 502551 502865 + hypothetical protein gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02395 SH03_RS02400 SH03_02395 SH03_RS02400 502894 506217 - miniconductance mechanosensitive channel MscM gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02400 SH03_RS02405 SH03_02400 psd psd 506239 507207 - phosphatidylserine decarboxylase proenzyme catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02405 SH03_RS02410 SH03_02405 SH03_RS02410 507304 508356 - ribosome small subunit-dependent GTPase A EngC%3B RsgA%3B CpgA%3B circularly permuted GTPase%3B ribosome small subunit-dependent GTPase A%3B has the pattern G4-G1-G3 as opposed to other GTPases%3B interacts strongly with 30S ribosome which stimulates GTPase activity gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02410 SH03_RS02415 SH03_02410 SH03_RS02415 508451 508996 + oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02415 SH03_RS02420 SH03_02415 SH03_RS02420 509207 509282 + tRNA-Gly tRNA gene483 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02420 SH03_RS02425 SH03_02420 SH03_RS02425 509319 509394 + tRNA-Gly tRNA gene484 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02425 SH03_RS02430 SH03_02425 SH03_RS02430 509430 509505 + tRNA-Gly tRNA gene485 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02430 SH03_RS02435 SH03_02430 SH03_RS02435 509775 510914 - epoxyqueuosine reductase gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02435 SH03_RS02440 SH03_02435 SH03_RS02440 510928 512460 + carbohydrate kinase gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02440 SH03_RS02445 SH03_02440 SH03_RS02445 512432 512893 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE needed for nucleoid integrity%3B possibly involved in cell wall synthesis gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02445 SH03_RS02450 SH03_02445 SH03_RS02450 512912 514249 + N-acetylmuramoyl-L-alanine amidase gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02450 SH03_RS02455 SH03_02450 SH03_RS02455 514259 516106 + DNA mismatch repair protein MutL gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02455 SH03_RS02460 SH03_02455 miaA miaA 516099 517049 + tRNA dimethylallyltransferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02460 SH03_RS02465 SH03_02460 hfq hfq 517135 517443 + RNA chaperone Hfq HF-I%2C host factor for RNA phage Q beta replication gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02465 SH03_RS02470 SH03_02465 SH03_RS02470 517519 518799 + GTPase HflX involved in modulation of proteins HflK and HflC%3B part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02470 SH03_RS02475 SH03_02470 SH03_RS02475 518885 520144 + cell division protein FtsH with HflC inhibits proteolysis of lambda cII protein by FtsH gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02475 SH03_RS02480 SH03_02475 SH03_RS02480 520147 521151 + modulator of FtsH protease HflC with HflK inhibits proteolysis of lambda cII protein by FtsH gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02480 SH03_RS02485 SH03_02480 SH03_RS02485 521233 521430 + membrane protein gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02485 SH03_RS02490 SH03_02485 SH03_RS02490 521534 522832 + adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02490 SH03_RS02495 SH03_02490 SH03_RS02495 523037 523462 + transcriptional regulator negatively regulates the transcription of genes upregulated by nitrosative stress gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02495 SH03_RS02500 SH03_02495 SH03_RS02500 523501 525942 + exoribonuclease R 3'-5'exoribonuclease that acts nonspecifically on poly(A)%2C poly(U) and ribosomal RNAs gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02500 SH03_RS02505 SH03_02500 SH03_RS02505 526122 526853 + 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB Specifically methylates the ribose of guanosine 2251 in 23S rRNA gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02505 SH03_RS02510 SH03_02505 SH03_RS02510 526980 527381 + DUF2170 domain-containing protein gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02510 SH03_RS02515 SH03_02510 SH03_RS02515 527400 528098 + PspA/IM30 family protein gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02515 SH03_RS02520 SH03_02515 SH03_RS02520 528149 528808 + DUF2491 domain-containing protein gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02520 SH03_RS02525 SH03_02520 SH03_RS02525 528826 529224 + hypothetical protein gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02525 SH03_RS02530 SH03_02525 SH03_RS02530 529234 529872 + DUF1190 domain-containing protein gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02530 SH03_RS02535 SH03_02530 SH03_RS02535 529875 531038 + ATP-Grasp family ATPase gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02535 SH03_RS02540 SH03_02535 SH03_RS02540 531122 532747 + DNA alkylation damage repair protein catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02540 SH03_RS02545 SH03_02540 SH03_RS02545 532864 533139 - DUF1471 domain-containing protein gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02545 SH03_RS02550 SH03_02545 SH03_RS02550 533288 533617 - lipoprotein BsmA in Escherichia coli%2C mutation of this gene affects biofilm maturation%2C stress response%2C and motility gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02550 SH03_RS02555 SH03_02550 SH03_RS02555 533799 534548 + esterase YjfP%3B esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro%3B unknown function and substrate in vivo gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02555 SH03_RS02560 SH03_02555 SH03_RS02560 534545 535300 - transcriptional regulator negative regulator of ulaG and ulaABCDEF gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02560 SH03_RS02565 SH03_02560 SH03_RS02565 535408 536472 - L-ascorbate-6-phosphate lactonase UlaG gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02565 SH03_RS02570 SH03_02565 SH03_RS02570 536827 538224 + ascorbate-specific permease IIC component UlaA gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02570 SH03_RS02575 SH03_02570 SH03_RS02575 538240 538545 + ascorbate-specific phosphotransferase enzyme IIB component involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02575 SH03_RS02580 SH03_02575 SH03_RS02580 538555 539019 + ascorbate-specific phosphotransferase enzyme IIA component involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02580 SH03_RS02585 SH03_02580 ulaD ulaD 539033 539683 + 3-keto-L-gulonate-6-phosphate decarboxylase ulaD catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02585 SH03_RS02590 SH03_02585 SH03_RS02590 539693 540547 + L-ribulose-5-phosphate 3-epimerase UlaE gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02590 SH03_RS02595 SH03_02590 araD araD 540547 541233 + L-ribulose-5-phosphate 4-epimerase UlaF catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02595 SH03_RS02600 SH03_02595 SH03_RS02600 541363 541638 - hypothetical protein gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02600 SH03_RS02605 SH03_02600 SH03_RS02605 541722 541841 + hypothetical protein gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02605 SH03_RS02610 SH03_02605 rpsF rpsF 541965 542360 + 30S ribosomal protein S6 binds cooperatively with S18 to the S15-16S complex%2C allowing platform assembly to continue with S11 and S21 gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02610 SH03_RS02615 SH03_02610 SH03_RS02615 542367 542681 + primosomal replication protein n binds single-stranded DNA at the primosome assembly site gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02615 SH03_RS02620 SH03_02615 rpsR rpsR 542686 542913 + 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02620 SH03_RS02625 SH03_02620 rplI rplI 542955 543404 + 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02625 SH03_RS02630 SH03_02625 SH03_RS02630 543475 544269 - hypothetical protein gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02630 SH03_RS02635 SH03_02630 SH03_RS02635 544616 544942 + hypothetical protein gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02635 SH03_RS02640 SH03_02635 SH03_RS02640 544926 545564 - OapA family protein gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02640 SH03_RS02645 SH03_02640 SH03_RS02645 545782 546402 + FKBP-type peptidyl-prolyl cis-trans isomerase FKBP-type%3B rotamase%3B catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02645 SH03_RS02650 SH03_02645 SH03_RS02650 546711 548123 + D-serine/D-alanine/glycine transporter gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02650 SH03_RS02655 SH03_02650 SH03_RS02655 548168 548830 - iron-sulfur cluster repair protein YtfE Involved in anaerobic NO protection and iron metabolism gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02655 SH03_RS02660 SH03_02655 SH03_RS02660 548938 549903 - hypothetical protein gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02660 SH03_RS02665 SH03_02660 SH03_RS02665 550011 550871 - quinone oxidoreductase 2 gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02665 SH03_RS02670 SH03_02665 SH03_RS02670 550870 551340 + HxlR family transcriptional regulator gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02670 SH03_RS02675 SH03_02670 cpdB cpdB 551469 553412 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic enzyme%3B functions during ribonucleic acid degradation%3B 2'%2C3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02675 SH03_RS02680 SH03_02675 SH03_RS02680 553602 554342 + 3'(2')%2C5'-bisphosphate nucleotidase CysQ catalyzes the formation of AMP from adenosine-3'%2C5'-bisphosphate gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02680 SH03_RS02685 SH03_02680 SH03_RS02685 554554 555492 + hypothetical protein gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02685 SH03_RS02690 SH03_02685 SH03_RS02690 555555 556109 - transcriptional regulator gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02690 SH03_RS02695 SH03_02690 SH03_RS02695 556434 556640 + DUF1107 domain-containing protein gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02695 SH03_RS02700 SH03_02695 SH03_RS02700 556719 558062 - hypothetical protein gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02700 SH03_RS02705 SH03_02700 SH03_RS02705 558385 559023 - peptide methionine sulfoxide reductase MsrA this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form%3B provides protection against oxidative stress gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02705 SH03_RS02710 SH03_02705 SH03_RS02710 559131 559259 + hypothetical protein gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02710 SH03_RS02715 SH03_02710 SH03_RS02715 559229 560962 + translocation and assembly module TamA gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02715 SH03_RS02720 SH03_02715 SH03_RS02720 560959 564738 + translocation and assembly module TamB gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02720 SH03_RS02725 SH03_02720 SH03_RS02725 564741 565082 + gamma-glutamylcyclotransferase YtfP gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02725 SH03_RS02730 SH03_02725 SH03_RS02730 565294 565545 + antitoxin ChpS part of the toxin-antitoxin ChpB-ChpS system gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02730 SH03_RS02735 SH03_02730 SH03_RS02735 565539 565889 + mRNA interferase ChpB toxin of the ChpB-ChpS toxin-antitoxin system gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02735 SH03_RS02740 SH03_02735 SH03_RS02740 565969 566499 - inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02740 SH03_RS02745 SH03_02740 SH03_RS02745 566809 567765 + ABC transporter substrate-binding protein gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02745 SH03_RS02750 SH03_02745 SH03_RS02750 567905 569407 + sugar ABC transporter ATPase gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02750 SH03_RS02755 SH03_02750 SH03_RS02755 569421 570443 + sugar ABC transporter permease gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02755 SH03_RS02760 SH03_02755 SH03_RS02760 570430 571425 + ABC transporter permease membrane component of a putative sugar ABC transporter system gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02760 SH03_RS02765 SH03_02760 SH03_RS02765 571458 572456 - fructose 1%2C6-bisphosphatase catalyzes the formation of D-fructose 6-phosphate from fructose-1%2C6-bisphosphate gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02765 SH03_RS02770 SH03_02765 SH03_RS02770 572632 574005 + UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2%2C6-diaminoheptandioate ligase ligates L-alanyl-gamma-D-glutamyl-meso-diaminopimelate to UDP-N-acetylmuramic acid for reincorporation into peptidoglycan gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02770 SH03_RS02775 SH03_02770 SH03_RS02775 574161 574712 - ribosome-associated UPF0307 family protein gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02775 SH03_RS02780 SH03_02775 pmbA pmbA 574806 576158 + metalloprotease PmbA protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02780 SH03_RS02785 SH03_02780 SH03_RS02785 576337 576702 + cytochrome B562 electron transport protein gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02785 SH03_RS02790 SH03_02785 SH03_RS02790 576747 577211 - anaerobic ribonucleoside-triphosphate reductase-activating protein activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02790 SH03_RS02795 SH03_02790 SH03_RS02795 577369 579507 - anaerobic ribonucleoside-triphosphate reductase Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02795 SH03_RS02800 SH03_02795 SH03_RS02800 579901 581556 - trehalose-6-phosphate hydrolase gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02800 SH03_RS02805 SH03_02800 SH03_RS02805 581606 583024 - PTS maltose transporter subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02805 SH03_RS02810 SH03_02805 treR treR 583146 584093 - trehalose repressor regulates genes involved in trehalose metabolism%3B binds the intermediate trehalose-6-phosphate%3B binds a dimer%3B regulates treBC operon gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02810 SH03_RS02815 SH03_02810 SH03_RS02815 584472 587168 + magnesium-translocating P-type ATPase P-type%3B involved in magnesium transport into the cytoplasm gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02815 SH03_RS02820 SH03_02815 SH03_RS02820 587374 587760 - reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02820 SH03_RS02825 SH03_02820 SH03_RS02825 587833 588294 - aspartate carbamoyltransferase regulatory chain involved in the allosteric regulation of aspartate carbamoyltransferase gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02825 SH03_RS02830 SH03_02825 SH03_RS02830 588307 589242 - aspartate carbamoyltransferase catalytic subunit gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02830 SH03_RS02835 SH03_02830 SH03_RS02835 589246 589380 - pyrBI operon leader peptide gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02835 SH03_RS02840 SH03_02835 SH03_RS02840 589360 589692 + hypothetical protein gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02840 SH03_RS02845 SH03_02840 SH03_RS02845 589661 590056 - endoribonuclease L-PSP gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02845 SH03_RS02850 SH03_02845 SH03_RS02850 590187 590900 - oxidoreductase gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02850 SH03_RS02855 SH03_02850 SH03_RS02855 590971 591564 + transcriptional regulator gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02855 SH03_RS02860 SH03_02855 SH03_RS02860 591709 592161 + DUF386 domain-containing protein gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02860 SH03_RS02865 SH03_02860 SH03_RS02865 592284 594098 + SopA-central-domain-like hexapeptide repeat protein gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02865 SH03_RS02870 SH03_02865 SH03_RS02870 594154 595158 - ornithine carbamoyltransferase chain I catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02870 SH03_RS02875 SH03_02870 SH03_RS02875 595320 595736 + regulator of ribonuclease activity B gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02875 SH03_RS02880 SH03_02875 SH03_RS02880 595881 596384 - GNAT family acetyltransferase gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02880 SH03_RS02885 SH03_02880 SH03_RS02885 596577 597773 + hypothetical protein gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02885 SH03_RS02890 SH03_02885 SH03_RS02890 597829 600684 - valine--tRNA ligase gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02890 SH03_RS02895 SH03_02890 SH03_RS02895 600684 601127 - DNA polymerase III subunit chi binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02895 SH03_RS02900 SH03_02895 SH03_RS02900 601287 602798 - cytosol aminopeptidase catalyzes the removal of N-terminal amino acids preferably from various peptides%3B a cyteinylglycinase%2C transcription regulator and site-specific recombination factor gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02900 SH03_RS02905 SH03_02900 SH03_RS02905 603065 604165 + LPS export ABC transporter permease LptF with LptBGC is involved in lipopolysaccharide export gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02905 SH03_RS02910 SH03_02905 SH03_RS02910 604165 605247 + LPS export ABC transporter permease LptG with LptABCF is involved in the transport of lipopolysaccharides gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02910 SH03_RS02915 SH03_02910 SH03_RS02915 605408 606910 - DUF853 domain-containing protein gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02915 SH03_RS02920 SH03_02915 SH03_RS02920 606988 607986 - transcriptional regulator gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02920 SH03_RS02925 SH03_02920 SH03_RS02925 608053 609372 - gnt-II system L-idonate transporter gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02925 SH03_RS02930 SH03_02925 SH03_RS02930 609434 610198 - gluconate 5-dehydrogenase Involved in the nonphosphorylative%2C ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02930 SH03_RS02935 SH03_02930 SH03_RS02935 610222 611253 - L-idonate 5-dehydrogenase (NAD(P)+) NAD-binding gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02935 SH03_RS02940 SH03_02935 idnK idnK 611470 612033 + thermosensitive gluconokinase gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02940 SH03_RS02945 SH03_02940 SH03_RS02945 612037 613056 - aldehyde reductase Ahr gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02945 SH03_RS02950 SH03_02945 SH03_RS02950 613252 613336 + tRNA-Leu tRNA gene589 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02950 SH03_RS02955 SH03_02950 SH03_RS02955 613597 614787 + integrase gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02955 SH03_RS02960 SH03_RS02960 SH03_RS02960 615073 615162 - nitrite extrusion protein 2 gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02960 SH03_RS02965 SH03_02960 SH03_RS02965 615119 615484 + transposase represses IS2 gene transcription gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02965 SH03_RS02970 SH03_02965 SH03_RS02970 615442 616347 + integrase gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02970 SH03_RS02985 SH03_02980 SH03_RS02985 617905 618075 + hypothetical protein gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02985 SH03_RS02990 SH03_02985 SH03_RS02990 618129 618350 + hypothetical protein gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02990 SH03_RS02995 SH03_02990 SH03_RS02995 618779 618922 + hypothetical protein gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS02995 SH03_RS03000 SH03_02995 SH03_RS03000 618950 620278 - transposase gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03000 SH03_RS03005 SH03_03000 SH03_RS03005 620905 622122 + MFS transporter membrane protein gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03005 SH03_RS03010 SH03_03005 SH03_RS03010 622134 623252 + oxidoreductase gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03010 SH03_RS03015 SH03_03010 SH03_RS03015 623473 623730 - hypothetical protein gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03015 SH03_RS03020 SH03_03015 SH03_RS03020 623753 623956 + hypothetical protein gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03020 SH03_RS03025 SH03_03020 SH03_RS03025 624008 624310 + transposase gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03025 SH03_RS03030 SH03_03025 SH03_RS03030 624313 625464 - transposase gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03030 SH03_RS03035 SH03_03030 SH03_RS03035 625421 625789 - transposase gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03035 SH03_RS03040 SH03_RS03040 SH03_RS03040 625805 626640 + transposase gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03040 SH03_RS03045 SH03_03040 SH03_RS03045 626723 626980 + transporter gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03045 SH03_RS03050 SH03_03045 SH03_RS03050 627537 628304 - Fe(3+) dicitrate transport ATP-binding protein FecE gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03050 SH03_RS03055 SH03_03050 fecD fecD 628305 629261 - Fe(3+) dicitrate ABC transporter permease Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter)%2C as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter. gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03055 SH03_RS03060 SH03_03055 fecC fecC 629258 630256 - Fe(3+) dicitrate ABC transporter permease part of the FecBCDE citrate-dependent iron (III) transport system gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03060 SH03_RS03065 SH03_03060 fecB fecB 630253 631155 - Fe(3+) dicitrate-binding periplasmic protein part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+) gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03065 SH03_RS03070 SH03_03065 SH03_RS03070 631200 633524 - fe(3+) dicitrate transporter fecA gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03070 SH03_RS03075 SH03_03070 SH03_RS03075 633611 634564 - protein FecR with FecA forms the FecAR signal transduction system%3B ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03075 SH03_RS03080 SH03_03075 SH03_RS03080 634561 635082 - RNA polymerase sigma factor FecI Member of the extracytoplasmic function sigma factors which are active under specific conditions%3B binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription%3B this sigma factor regulates the genes for iron dicitrate transport gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03080 SH03_RS03085 SH03_03080 SH03_RS03085 635293 635493 - transposase gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03085 SH03_RS03095 SH03_03090 SH03_RS03095 635862 636071 + transposase gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03095 SH03_RS03100 SH03_03095 SH03_RS03100 636185 637171 - transcriptional regulator gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03100 SH03_RS03105 SH03_03100 SH03_RS03105 637271 637441 - hypothetical protein gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03105 SH03_RS03110 SH03_03105 SH03_RS03110 637518 638867 - transporter gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03110 SH03_RS03115 SH03_03110 SH03_RS03115 638974 640941 - dehydratase gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03115 SH03_RS03120 SH03_03115 SH03_RS03120 640952 641887 - 2-keto-3-deoxy-galactonate aldolase gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03120 SH03_RS03125 SH03_03120 SH03_RS03125 641862 642650 - transcriptional regulator gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03125 SH03_RS03130 SH03_03125 SH03_RS03130 642953 643735 - transcriptional regulator gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03130 SH03_RS03135 SH03_03130 SH03_RS03135 643752 644384 - protein SgcE gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03135 SH03_RS03140 SH03_03135 SH03_RS03140 644396 644827 - phosphotransferase enzyme IIA component gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03140 SH03_RS03145 SH03_03140 SH03_RS03145 644958 645764 - nucleoside triphosphatase gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03145 SH03_RS03150 SH03_03145 SH03_RS03150 645777 647090 - PTS system EIIC permease component gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03150 SH03_RS03155 SH03_03150 SH03_RS03155 647102 647383 - PTS sugar transporter subunit IIB gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03155 SH03_RS03160 SH03_03155 SH03_RS03160 647377 648498 - endoglucanase gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03160 SH03_RS03165 SH03_03160 SH03_RS03165 649284 650030 - methyltransferase gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03165 SH03_RS03170 SH03_03165 SH03_RS03170 650086 650631 - GNAT family acetyltransferase gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03170 SH03_RS03175 SH03_03170 SH03_RS03175 650643 650900 - hypothetical protein gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03175 SH03_RS03180 SH03_03175 SH03_RS03180 651391 651522 - hypothetical protein gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03180 SH03_RS03185 SH03_03180 SH03_RS03185 651686 651895 + DNA helicase superfamily I gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03185 SH03_RS03190 SH03_03185 SH03_RS03190 651862 652878 + hypothetical protein gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03190 SH03_RS03195 SH03_03190 SH03_RS03195 653461 654441 - 9-O-acetyl-N-acetylneuraminic acid deacetylase gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03195 SH03_RS03200 SH03_03195 SH03_RS03200 654506 655612 - N-acetylneuraminate epimerase gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03200 SH03_RS03205 SH03_03200 SH03_RS03205 655632 656180 - porin gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03205 SH03_RS03210 SH03_03205 SH03_RS03210 656720 656866 + hypothetical protein gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03210 SH03_RS03215 SH03_RS03215 SH03_RS03215 657148 657543 - hypothetical protein gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03215 SH03_RS03220 SH03_03215 SH03_RS03220 657804 658406 + type 1 fimbriae regulatory protein FimB gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03220 SH03_RS03225 SH03_03220 SH03_RS03225 659146 659649 + transposase gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03225 SH03_RS03230 SH03_03225 SH03_RS03230 659702 660256 + tyrosine recombinase inversion of on/off regulator of fimA gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03230 SH03_RS03235 SH03_03230 SH03_RS03235 660336 660524 - hypothetical protein gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03235 SH03_RS03240 SH03_03235 fimA fimA 660738 661286 + type-1 fimbrial protein%2C A chain gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03240 SH03_RS03245 SH03_03240 SH03_RS03245 661393 661890 + fimbrin fimI gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03245 SH03_RS03250 SH03_03245 SH03_RS03250 661927 662652 + chaperone protein FimC gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03250 SH03_RS03255 SH03_03250 SH03_RS03255 662719 665355 + outer membrane usher protein FimD gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03255 SH03_RS03260 SH03_03255 SH03_RS03260 665365 665895 + protein FimF gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03260 SH03_RS03265 SH03_03260 SH03_RS03265 665908 666411 + protein FimG gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03265 SH03_RS03270 SH03_03265 SH03_RS03270 666431 667333 + protein FimH gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03270 SH03_RS03275 SH03_03270 SH03_RS03275 667576 668919 - gluconate transporter gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03275 SH03_RS03280 SH03_03275 SH03_RS03280 669077 669307 + hypothetical protein gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03280 SH03_RS03285 SH03_03280 SH03_RS03285 669259 670443 + mannonate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03285 SH03_RS03290 SH03_03285 SH03_RS03290 670524 671984 + D-mannonate oxidoreductase gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03290 SH03_RS03295 SH03_03290 SH03_RS03295 672006 672200 - hypothetical protein gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03295 SH03_RS03300 SH03_03295 SH03_RS03300 672199 672972 + Uxu operon transcriptional regulator regulates the expression of uxuBA gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03300 SH03_RS03305 SH03_03300 SH03_RS03305 673113 673943 - hypothetical protein gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03305 SH03_RS03310 SH03_03305 SH03_RS03310 673861 674034 - hypothetical protein gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03310 SH03_RS03320 SH03_03315 SH03_RS03320 674516 674650 + hypothetical protein gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03320 SH03_RS03325 SH03_03320 iraD iraD 674616 675008 + anti-adapter protein IraD inhibitor of RssB activity in response to DNA damage%3B blocks degradation of stationary phase sigma factor RpoS gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03325 SH03_RS03330 SH03_03325 SH03_RS03330 675001 675912 - transcriptional regulator gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03330 SH03_RS03335 SH03_03330 SH03_RS03335 675977 677149 - isoaspartyl dipeptidase gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03335 SH03_RS03340 SH03_03335 SH03_RS03340 677162 677623 - hypothetical protein gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03340 SH03_RS03345 SH03_03340 SH03_RS03345 677620 678303 - nucleoside recognition pore and gate family inner membrane transporter gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03345 SH03_RS03350 SH03_03345 SH03_RS03350 678553 679107 + RNA 2'-phosphotransferase in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate%3B functions in tRNA splicing%3B the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03350 SH03_RS03355 SH03_03350 SH03_RS03355 679120 680298 - DUF1228 family inner membrane MFS superfamily transporter gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03355 SH03_RS03360 SH03_03355 SH03_RS03360 680366 681226 - SdiA-regulated family membrane-anchored protein%3B phytase-like esterase gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03360 SH03_RS03365 SH03_03360 SH03_RS03365 681291 681548 - hypothetical protein gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03365 SH03_RS03370 SH03_03365 SH03_RS03370 681545 682312 - 2-hydroxyglutaryl-CoA dehydratase activator gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03370 SH03_RS03375 SH03_03370 SH03_RS03375 682322 683473 - 2-hydroxyglutaryl-CoA dehydratase gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03375 SH03_RS03380 SH03_03375 SH03_RS03380 683589 684869 - zinc-type alcohol dehydrogenase-like protein gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03380 SH03_RS03385 SH03_03380 SH03_RS03385 684910 686142 - multidrug resistance protein MdtM is involved in resistance to acriflavine%2C chloramphenicol%2C norfloxacin%2C ethidium bromide and TPP gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03385 SH03_RS03390 SH03_RS03390 SH03_RS03390 686621 687541 + hypothetical protein gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03390 SH03_RS03395 SH03_03390 SH03_RS03395 687785 689197 - transcriptional regulator gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03395 SH03_RS03400 SH03_03395 SH03_RS03400 689374 689538 + DUF1127 domain-containing protein gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03400 SH03_RS03405 SH03_03400 SH03_RS03405 689989 691554 + hypothetical protein gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03405 SH03_RS03410 SH03_03405 SH03_RS03410 691758 694478 + hypothetical protein gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03410 SH03_RS03415 SH03_03410 SH03_RS03415 694535 695611 - protein mcrC gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03415 SH03_RS03420 SH03_03415 SH03_RS03420 695581 696960 - 5-methylcytosine-specific restriction enzyme B McrB protein together with McrC forms the McrBC restriction system%3B recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines)%3B appears to act against 5-methylcytosine preceded by a purine residue gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03420 SH03_RS03425 SH03_03420 SH03_RS03425 697122 697463 - hypothetical protein involved in the degradation of RNA%3B may be involved in the recycling of RNA during the SOS response gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03425 SH03_RS03430 SH03_03425 SH03_RS03430 697691 699085 - type-1 restriction enzyme EcoKI specificity protein gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03430 SH03_RS03435 SH03_03430 SH03_RS03435 699082 700671 - type I restriction enzyme EcoKI M protein gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03435 SH03_RS03440 SH03_03435 SH03_RS03440 700872 704384 - type I restriction enzyme EcoKI R protein gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03440 SH03_RS03445 SH03_03440 SH03_RS03445 704827 706032 - MFS transporter gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03445 SH03_RS03450 SH03_03445 SH03_RS03450 706114 706737 + TetR family transcriptional regulator gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03450 SH03_RS03455 SH03_RS03455 SH03_RS03455 706841 707410 + restriction endonuclease gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03455 SH03_RS03460 SH03_03455 SH03_RS03460 707456 708412 - metal-binding GTPase gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03460 SH03_RS03465 SH03_03460 SH03_RS03465 708423 708626 - hypothetical protein gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03465 SH03_RS03470 SH03_03465 SH03_RS03470 708676 710826 - hypothetical protein gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03470 SH03_RS03475 SH03_RS03475 SH03_RS03475 710871 711044 - hypothetical protein gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03475 SH03_RS03480 SH03_03475 SH03_RS03480 711204 712859 + methyl-accepting chemotaxis protein I serine sensor receptor gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03480 SH03_RS03485 SH03_03480 SH03_RS03485 712908 714269 - L-galactonate transporter gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03485 SH03_RS03490 SH03_03485 SH03_RS03490 714484 715398 - transcriptional regulator gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03490 SH03_RS03495 SH03_03490 SH03_RS03495 715537 716559 + L-galactonate-5-dehydrogenase gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03495 SH03_RS03500 SH03_03495 SH03_RS03500 716697 718988 - phosphoglycerol transferase I catalyzes the transfer of phosphoglycerol to the glucan backbone gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03500 SH03_RS03505 SH03_03500 SH03_RS03505 719242 719733 - hypothetical protein gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03505 SH03_RS03510 SH03_03505 SH03_RS03510 719785 720522 - DNA replication protein DnaC acts to load the DnaB helicase onto the initiation site during DNA replication gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03510 SH03_RS03515 SH03_03510 SH03_RS03515 720525 721064 - primosomal protein 1 This protein is required for primosome-dependent normal DNA replication%3B it is also involved in inducing stable DNA replication during SOS response. It forms%2C in concert with dnaB protein and other prepriming proteins dnaC%2C N%2C N'%2C N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03515 SH03_RS03520 SH03_03515 SH03_RS03520 721171 721644 - DUF3815 domain-containing protein gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03520 SH03_RS03525 SH03_03520 SH03_RS03525 721635 722405 - hypothetical protein gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03525 SH03_RS03530 SH03_03525 SH03_RS03530 723024 723749 + transcriptional regulator gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03530 SH03_RS03535 SH03_03530 SH03_RS03535 723707 724384 + transcriptional activator protein BglJ regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03535 SH03_RS03540 SH03_03535 SH03_RS03540 724422 725210 - ferric iron reductase FhuF gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03540 SH03_RS03545 SH03_03540 SH03_RS03545 725312 725587 + hypothetical protein gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03545 SH03_RS03550 SH03_03545 SH03_RS03550 725626 725712 - tRNA-Leu tRNA gene707 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03550 SH03_RS03555 SH03_03550 SH03_RS03555 725747 725833 - tRNA-Leu tRNA gene708 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03555 SH03_RS03560 SH03_03555 SH03_RS03560 725862 725948 - tRNA-Leu tRNA gene709 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03560 SH03_RS03565 SH03_03560 rsmC rsmC 726216 727247 - ribosomal RNA small subunit methyltransferase C 16S rRNA M2G1207 methyltransferase%3B one of many enzymes that modify bases of the ribosomal RNA%3B this enzyme methylates the G at position 1207 of the small ribosomal subunit gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03565 SH03_RS03570 SH03_03565 SH03_RS03570 727350 727763 + DNA polymerase III subunit psi with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03570 SH03_RS03575 SH03_03570 rimI rimI 727732 728178 + ribosomal-protein-alanine acetyltransferase alanine acetyltransferase that specifically acetylates ribosomal protein S18 gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03575 SH03_RS03580 SH03_03575 SH03_RS03580 728193 728870 + pyrimidine 5'-nucleotidase YjjG manganese-dependent 5'-nucleotidase%3B specific for 5'-UMP%2C 5'-dUMP%2C and 5'-dTMP%3B member of haloacid dehalogenase (HAD)-like hydrolase superfamily gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03580 SH03_RS03585 SH03_03580 prfC prfC 728961 730550 + peptide chain release factor 3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred%3B GDP/GTP-binding protein gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03585 SH03_RS03590 SH03_03585 SH03_RS03590 730943 731548 + osmotically-inducible protein Y gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03590 SH03_RS03595 SH03_03590 SH03_RS03595 731675 731836 + hypothetical protein gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03595 SH03_RS03600 SH03_03595 SH03_RS03600 731958 733031 + patatin gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03600 SH03_RS03605 SH03_03600 SH03_RS03605 733028 733807 + DNase gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03605 SH03_RS03610 SH03_03605 SH03_RS03610 734227 735090 - glycine radical enzyme activase gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03610 SH03_RS03615 SH03_03610 SH03_RS03615 735062 736612 - DUF3029 domain-containing protein gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03615 SH03_RS03620 SH03_03615 SH03_RS03620 736664 736765 + hypothetical protein gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03620 SH03_RS03625 SH03_03620 SH03_RS03625 736870 737649 + deoxyribose-phosphate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03625 SH03_RS03630 SH03_03625 SH03_RS03630 737776 739098 + thymidine phosphorylase gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03630 SH03_RS03635 SH03_03630 SH03_RS03635 739150 740373 + phosphopentomutase gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03635 SH03_RS03640 SH03_03635 deoD deoD 740430 741149 + purine nucleoside phosphorylase catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03640 SH03_RS03645 SH03_03640 SH03_RS03645 741316 742647 + kinase gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03645 SH03_RS03650 SH03_03645 lplA lplA 742648 743664 - lipoate-protein ligase A Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03650 SH03_RS03655 SH03_03650 SH03_RS03655 743692 744336 - protein Smp gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03655 SH03_RS03660 SH03_03655 serB serB 744442 745410 + phosphoserine phosphatase catalyzes the formation of serine from O-phosphoserine gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03660 SH03_RS03665 SH03_03660 SH03_RS03665 745459 746841 + DNA repair protein RadA Sms%3B stabilizes the strand-invasion intermediate during the DNA repair%3B involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03665 SH03_RS03670 SH03_03665 SH03_RS03670 746862 748094 + trifunctional NAD biosynthesis/regulator protein NadR catalyzes the formation of NAD(+) from nicotinamide ribonucleotide%3B catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside%3B also has a regulatory function gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03670 SH03_RS03675 SH03_03670 SH03_RS03675 748128 748295 + transcriptional regulator gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03675 SH03_RS03680 SH03_03675 SH03_RS03680 748402 750069 - energy-dependent translational throttle protein EttA ChvD%3B in Agrobacterium tumefaciens%2C mutations in both Walker boxes were found to affect virulence gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03680 SH03_RS03685 SH03_03680 SH03_RS03685 750280 752217 + murein transglycosylase catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03685 SH03_RS03690 SH03_03685 SH03_RS03690 752307 752633 + Trp operon repressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03690 SH03_RS03695 SH03_03690 yjjX yjjX 752780 753292 - non-canonical purine NTP phosphatase pyrophosphatase%3B has activity against dUTP and dITP%3B the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226%3B in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms%3B in Escherichia coli overexpression of this gene leads to resistance to an HMP analog gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03695 SH03_RS03700 SH03_03695 SH03_RS03700 753344 753991 + phosphoglycerate mutase GpmB catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03700 SH03_RS03705 SH03_03700 SH03_RS03705 753988 754857 - right origin-binding protein AraC family%3B binds to the right arm of the replication origin oriC gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03705 SH03_RS03710 SH03_03705 SH03_RS03710 755068 755541 + protein CreA gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03710 SH03_RS03715 SH03_03710 SH03_RS03715 755554 756243 + two-component system response regulator response regulator in two-component regulatory system with CreC%3B CreB protein is phosphorylated by sensor protein phospho-CreC%3B involved in catabolic regulation gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03715 SH03_RS03720 SH03_03715 SH03_RS03720 756243 757667 + two-component system sensor histidine kinase part of a two-component regulatory system with CreB or PhoB%3B involved in catabolic regulation gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03720 SH03_RS03725 SH03_03720 SH03_RS03725 757725 759077 + protein CreD gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03725 SH03_RS03730 SH03_03725 SH03_RS03730 759137 759853 - two-component system response regulator gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03730 SH03_RS03735 SH03_03730 SH03_RS03735 759949 760089 + hypothetical protein gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03735 SH03_RS03740 SH03_03735 SH03_RS03740 760489 761175 + methyltransferase member of the SPOUT superfamily of methyltransferases gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03740 SH03_RS03745 SH03_03740 thrL thrL 761389 761454 + thr operon leader peptide involved in threonine biosynthesis%3B controls the expression of the thrLABC operon gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03745 SH03_RS03750 SH03_03745 thrA thrA 761536 763998 + bifunctional aspartokinase/homoserine dehydrogenase 1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03750 SH03_RS03755 SH03_03750 SH03_RS03755 764000 764932 + homoserine kinase catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03755 SH03_RS03760 SH03_03755 SH03_RS03760 764933 766219 + threonine synthase gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03760 SH03_RS03765 SH03_03760 SH03_RS03765 766287 766436 + hypothetical protein gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03765 SH03_RS03770 SH03_03765 SH03_RS03770 766433 766729 + DUF2502 domain-containing protein gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03770 SH03_RS03775 SH03_03770 SH03_RS03775 766882 767658 - hypothetical protein gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03775 SH03_RS03780 SH03_03775 SH03_RS03780 767728 769158 - transporter gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03780 SH03_RS03785 SH03_03780 SH03_RS03785 769437 770390 + transaldolase 1 gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03785 SH03_RS03790 SH03_03785 mogA mogA 770505 771092 + molybdopterin adenylyltransferase forms a trimer%3B related to eukaryotic protein gephyrin%3B functions during molybdenum cofactor biosynthesis gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03790 SH03_RS03795 SH03_03790 SH03_RS03795 771127 771693 - succinate-acetate/proton symporter SatP gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03795 SH03_RS03800 SH03_03795 SH03_RS03800 771842 772555 - hypothetical protein gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03800 SH03_RS03805 SH03_03800 SH03_RS03805 772581 772985 - hypothetical protein gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03805 SH03_RS03810 SH03_03805 dnaK dnaK 773362 775278 + molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03810 SH03_RS03815 SH03_03810 SH03_RS03815 775367 776497 + molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03815 SH03_RS03820 SH03_03815 SH03_RS03820 776644 777756 + transposase gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03820 SH03_RS03825 SH03_03820 SH03_RS03825 777950 778102 - protein HokC gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03825 SH03_RS03830 SH03_03825 nhaA nhaA 778688 779854 + Na+/H+ antiporter NhaA exports sodium by using the electrochemical proton gradient to allow protons into the cell%3B functions in adaptation to high salinity and alkaline pH%3B activity increases at higher pH%3B downregulated at acidic pH gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03830 SH03_RS03835 SH03_03830 nhaR nhaR 779920 780819 + transcriptional regulator Na+/H+ antiporter regulatory protein%3B activates the genes nhaA and osmC gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03835 SH03_RS03840 SH03_03835 SH03_RS03840 781010 781513 - transposase gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03840 SH03_RS03845 SH03_03840 rpsT rpsT 782014 782277 - 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03845 SH03_RS03850 SH03_03845 SH03_RS03850 782380 782598 + hypothetical protein gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03850 SH03_RS03855 SH03_03850 SH03_RS03855 782606 783547 + bifunctional riboflavin kinase/FMN adenylyltransferase gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03855 SH03_RS03860 SH03_03855 ileS ileS 783590 786406 + isoleucine--tRNA ligase IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase family type 1 subfamily%3B some organisms carry two different copies of this enzyme gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03860 SH03_RS03865 SH03_03860 lspA lspA 786406 786900 + lipoprotein signal peptidase lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03865 SH03_RS03870 SH03_03865 SH03_RS03870 787025 787474 + peptidyl-prolyl cis-trans isomerase rotamase%3B accelerates isomerization of the peptidyl prolyl bond%2C involved in the folding of proteases gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03870 SH03_RS03875 SH03_03870 ispH ispH 787476 788426 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03875 SH03_RS03880 SH03_03875 SH03_RS03880 788492 789406 + non-specific ribonucleoside hydrolase RihC catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03880 SH03_RS03885 SH03_03880 SH03_RS03885 789573 790394 + 4-hydroxy-tetrahydrodipicolinate reductase catalyzes the reduction of 2%2C3-dihydrodipicolinate to 2%2C3%2C4%2C5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03885 SH03_RS03890 SH03_03885 SH03_RS03890 790436 790603 - hypothetical protein gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03890 SH03_RS03895 SH03_03890 SH03_RS03895 790637 790732 - hypothetical protein gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03895 SH03_RS03900 SH03_03895 SH03_RS03900 790850 791998 + carbamoyl-phosphate synthase small chain catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03900 SH03_RS03905 SH03_03900 carB carB 792016 795237 + carbamoyl-phosphate synthase large chain four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03905 SH03_RS03910 SH03_03905 SH03_RS03910 795285 795464 - hypothetical protein gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03910 SH03_RS03915 SH03_03910 SH03_RS03915 795499 795894 + transcriptional activatory protein CaiF regulator of carnitine metabolism%3B induces the caiTABCDE and fixABCX operons gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03915 SH03_RS03920 SH03_03915 SH03_RS03920 795980 796570 - carnitine operon protein CaiE involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03920 SH03_RS03925 SH03_03920 SH03_RS03925 796576 797361 - carnitinyl-CoA dehydratase catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03925 SH03_RS03930 SH03_03925 caiC caiC 797470 799023 - crotonobetaine/carnitine-CoA ligase gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03930 SH03_RS03935 SH03_03930 SH03_RS03935 799097 800314 - L-carnitine CoA-transferase catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA%2C also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03935 SH03_RS03940 SH03_03935 SH03_RS03940 800443 801585 - crotonobetainyl-CoA dehydrogenase catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03940 SH03_RS03945 SH03_03940 SH03_RS03945 801616 803130 - L-carnitine/gamma-butyrobetaine antiporter catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03945 SH03_RS03950 SH03_03945 SH03_RS03950 803602 804372 + protein FixA required for anaerobic carnitine reduction%2C may act to transfer electrons to crotonobetaine reductase gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03950 SH03_RS03955 SH03_03950 SH03_RS03955 804387 805328 + protein FixB gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03955 SH03_RS03960 SH03_03955 SH03_RS03960 805379 806665 + protein FixC FAD/NAD(P)-binding domain%3B possibly part of an electron transfer system required for anaerobic carnitine reduction gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03960 SH03_RS03965 SH03_03960 SH03_RS03965 806662 806949 + ferredoxin-like protein FixX gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03965 SH03_RS03970 SH03_03965 SH03_RS03970 807006 808337 + transporter gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03970 SH03_RS03975 SH03_03970 SH03_RS03975 808445 808975 + glutathione-regulated potassium-efflux system ancillary protein KefF Required for full activity of KefC%2C a potassium-proton antiporter gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03975 SH03_RS03980 SH03_03975 SH03_RS03980 808968 810830 + glutathione-regulated potassium-efflux system protein KefC transport system that facilitates potassium-efflux gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03980 SH03_RS03985 SH03_03980 folA folA 811022 811501 + dihydrofolate reductase catalyzes the reduction of dihydrofolate to tetrahydrofolate gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03985 SH03_RS03990 SH03_03985 apaH apaH 811579 812421 - diadenosine tetraphosphatase hydrolyzes P(1)%2CP(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03990 SH03_RS03995 SH03_03990 apaG apaG 812428 812805 - protein ApaG protein associated with Co2+ and Mg2+ efflux gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS03995 SH03_RS04000 SH03_03995 ksgA ksgA 812808 813629 - ribosomal RNA small subunit methyltransferase A in Escherichia coli this enzyme catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA%3B mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin%3B members of this protein family have secondary functions gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04000 SH03_RS04005 SH03_04000 pdxA pdxA 813626 814615 - 4-hydroxythreonine-4-phosphate dehydrogenase catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04005 SH03_RS04010 SH03_04005 SH03_RS04010 814615 815901 - chaperone SurA Chaperone involved in the folding of extracytoplasmic proteins%2C especially OmpA%2C OmpF and LamB gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04010 SH03_RS04015 SH03_04010 SH03_RS04015 815954 818308 - LPS-assembly protein LptD is involved in outer membrane permeability gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04015 SH03_RS04020 SH03_04015 djlA djlA 818563 819378 + dnaJ-like protein DjlA functions as a co-chaperone with DnaK%3B involved in regulation of colanic acid capsule%3B inner membrane protein%3B dimerized via transmembrane domain%3B J-like domain is cytoplasmic and can functionally substitute for DnaJ%3B stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04020 SH03_RS04025 SH03_RS04025 SH03_RS04025 819673 820478 + UDP pyrophosphate phosphatase gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04025 SH03_RS04030 SH03_04025 SH03_RS04030 820886 821545 - ribosomal large subunit pseudouridine synthase A catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04030 SH03_RS04035 SH03_04030 SH03_RS04035 821557 824463 - RNA polymerase-associated protein RapA transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP%2C when it is trapped or immobilized on tightly supercoiled DNA gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04035 SH03_RS04040 SH03_04035 SH03_RS04040 824628 826979 - DNA polymerase II Has polymerase%2C DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04040 SH03_RS04045 SH03_04040 araD araD 827054 827749 - L-ribulose-5-phosphate 4-epimerase catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04045 SH03_RS04050 SH03_04045 SH03_RS04050 828034 829536 - L-arabinose isomerase catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04050 SH03_RS04055 SH03_04050 SH03_RS04055 829547 831247 - ribulokinase catalyzes the phosphorylation of ribulose to ribulose 5-phosphate gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04055 SH03_RS04060 SH03_04055 SH03_RS04060 831586 832464 + arabinose operon regulatory protein positive and negative regulator%3B regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04060 SH03_RS04065 SH03_04060 SH03_RS04065 832550 833314 + hypothetical protein gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04065 SH03_RS04070 SH03_04065 thiQ thiQ 833428 834126 - thiamine import ATP-binding protein ThiQ with TbpA and ThiP is part of the thiamine and TPP transport system gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04070 SH03_RS04075 SH03_04070 thiP thiP 834110 835720 - thiamine ABC transporter permease permease%3B with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell%3B repressed in presence of exogenous thiamine gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04075 SH03_RS04080 SH03_04075 tbpA tbpA 835696 836679 - thiamine-binding periplasmic protein part of the thiamine and TPP transport system tbpA-thiPQ gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04080 SH03_RS04085 SH03_04080 SH03_RS04085 836843 838498 - transcriptional regulator activates sgrS under glucose-phosphate stress conditions gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04085 SH03_RS04090 SH03_04085 SH03_RS04090 838587 838718 + inhibitor of glucose uptake gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04090 SH03_RS04095 SH03_04090 SH03_RS04095 838820 839998 + sugar efflux transporter A gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04095 SH03_RS04100 SH03_04095 leuD leuD 840047 840652 - 3-isopropylmalate dehydratase small subunit catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis%3B forms a heterodimer of LeuC/D gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04100 SH03_RS04105 SH03_04100 SH03_RS04105 840663 842063 - 3-isopropylmalate dehydratase large subunit dehydratase component%2C catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04105 SH03_RS04110 SH03_04105 SH03_RS04110 842066 843157 - 3-isopropylmalate dehydrogenase gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04110 SH03_RS04115 SH03_04110 SH03_RS04115 843157 844728 - 2-isopropylmalate synthase gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04115 SH03_RS04120 SH03_04115 SH03_RS04120 844821 844907 - leu operon leader peptide involved in attenuation control of the leuABCD operon in leucine biosynthesis gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04120 SH03_RS04125 SH03_04120 leuO leuO 845567 846511 + transcriptional regulator activator for leuABCD operon%3B member of LysR family of transcriptional activators gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04125 SH03_RS04130 SH03_04125 SH03_RS04130 846829 848553 + acetolactate synthase isozyme 3 large subunit catalyzes the formation of 2-acetolactate from pyruvate%2C leucine sensitive gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04130 SH03_RS04135 SH03_04130 ilvH ilvH 848556 849047 + acetolactate synthase isozyme 3 small subunit with IlvI catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase 3 small subunit gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04135 SH03_RS04140 SH03_04135 SH03_RS04140 849059 849145 + fruR/shl operon leader peptide gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04140 SH03_RS04145 SH03_04140 SH03_RS04145 849227 850231 + catabolite repressor/activator binds D-fructose as an inducer%3B involved in regulation of operons for central pathways of carbon metabolism gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04145 SH03_RS04150 SH03_04145 SH03_RS04150 850833 851291 + transcriptional regulator MraZ MraZ%3B UPF0040%3B crystal structure shows similarity to AbrB gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04150 SH03_RS04155 SH03_04150 SH03_RS04155 851293 852234 + ribosomal RNA small subunit methyltransferase H gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04155 SH03_RS04160 SH03_04155 SH03_RS04160 852231 852596 + cell division protein FtsL membrane bound cell division protein at septum containing leucine zipper motif gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04160 SH03_RS04165 SH03_04160 SH03_RS04165 852612 854378 + peptidoglycan synthase FtsI penicillin-binding protein 3%3B transpeptidase involved in septal peptidoglycan synthesis gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04165 SH03_RS04170 SH03_04165 murE murE 854365 855852 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2 6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04170 SH03_RS04175 SH03_04170 murF murF 855849 857207 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04175 SH03_RS04180 SH03_04175 mraY mraY 857201 858283 + phospho-N-acetylmuramoyl-pentapeptide transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04180 SH03_RS04185 SH03_04180 murD murD 858286 859602 + UDP-N-acetylmuramoylalanine--D-glutamate ligase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04185 SH03_RS04190 SH03_04185 SH03_RS04190 859602 860846 + lipid II flippase FtsW gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04190 SH03_RS04195 SH03_04190 murG murG 860843 861910 + UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase N-acetylglucosaminyl transferase%3B UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04195 SH03_RS04200 SH03_04195 SH03_RS04200 861964 863439 + UDP-N-acetylmuramate--L-alanine ligase gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04200 SH03_RS04205 SH03_04200 ddl ddl 863432 864352 + D-alanine--D-alanine ligase B D-alanine--D-alanine ligase%3B DdlA%3B DdlB%3B cytoplasmic%3B catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis%3B there are two forms of this enzyme in Escherichia coli gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04205 SH03_RS04210 SH03_04205 SH03_RS04210 864354 865184 + cell division protein FtsQ involved in septum formation gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04210 SH03_RS04215 SH03_04210 ftsA ftsA 865181 866443 + cell division protein FtsA ATP-binding involved in recruitment of FtsK to Z ring%3B essential cell division protein%3B colocalizes with FtsZ through direct interaction to the septal ring structure%3B structurally similar to eukaryotic actin%3B binds directly to the cell membrane gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04215 SH03_RS04220 SH03_04215 SH03_RS04220 866504 867655 + cell division protein FtsZ GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04220 SH03_RS04225 SH03_04220 lpxC lpxC 867756 868673 + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase zinc-dependent%3B catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04225 SH03_RS04230 SH03_04225 SH03_RS04230 868904 869416 + secretion monitor secM translational pause allows for the initiation of secA translation gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04230 SH03_RS04235 SH03_04230 secA secA 869478 872183 + protein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04235 SH03_RS04240 SH03_04235 SH03_RS04240 872243 872632 + 8-oxo-dGTP diphosphatase gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04240 SH03_RS04245 SH03_04240 SH03_RS04245 872763 872897 - hypothetical protein gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04245 SH03_RS04250 SH03_04245 SH03_RS04250 872848 873045 - DNA gyrase inhibitor YacG inhibits supercoiling by DNA gyrase by binding to the GyrB subunit gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04250 SH03_RS04255 SH03_04250 SH03_RS04255 873055 873798 - cell division protein ZapD gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04255 SH03_RS04260 SH03_04255 coaE coaE 873798 874418 - dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04260 SH03_RS04265 SH03_04260 SH03_RS04265 874643 875686 + GMP reductase catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04265 SH03_RS04270 SH03_04265 SH03_RS04270 875721 876923 - protein transport protein HofC gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04270 SH03_RS04275 SH03_04270 SH03_RS04275 876913 878298 - protein transport protein HofB gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04275 SH03_RS04280 SH03_04275 SH03_RS04280 878308 878748 - prepilin peptidase-dependent protein D gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04280 SH03_RS04285 SH03_04280 SH03_RS04285 878770 878994 + hypothetical protein gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04285 SH03_RS04290 SH03_04285 SH03_RS04290 878951 879844 - nicotinate-nucleotide pyrophosphorylase [carboxylating] catalyzes the formation of pyridine-2%2C3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04290 SH03_RS04295 SH03_04290 SH03_RS04295 879932 880483 + 1%2C6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04295 SH03_RS04300 SH03_04295 SH03_RS04300 880480 881334 + protein AmpE involved in regulation of beta-lactamase%3B putative signaling protein gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04300 SH03_RS04305 SH03_04300 SH03_RS04305 881377 882747 - aromatic amino acid transporter gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04305 SH03_RS04310 SH03_04305 pdhR pdhR 883291 884055 + pyruvate dehydrogenase complex repressor activates lctPRD operon%3B autoregulates itself through repression of pdhR-aceEF-lpdA operon%3B regulates pyruvate dehydrogenase complex gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04310 SH03_RS04315 SH03_04310 aceE aceE 884216 886879 + pyruvate dehydrogenase E1 component E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04315 SH03_RS04320 SH03_04315 aceF aceF 886894 888786 + dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex E2 component of pyruvate dehydrogenase multienzyme complex%3B in Escherichia coli AceF contains three N-terminal lipoyl domains gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04320 SH03_RS04325 SH03_04320 SH03_RS04325 889111 890535 + dihydrolipoyl dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04325 SH03_RS04330 SH03_04325 SH03_RS04330 890606 892459 - DUF3300 domain-containing protein gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04330 SH03_RS04335 SH03_04330 SH03_RS04335 892814 895411 + aconitate hydratase 2 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04335 SH03_RS04340 SH03_04335 SH03_RS04340 895587 895949 + hypothetical protein gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04340 SH03_RS04345 SH03_04340 SH03_RS04345 895987 896781 - S-adenosylmethionine decarboxylase proenzyme S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04345 SH03_RS04350 SH03_04345 SH03_RS04350 896797 897663 - polyamine aminopropyltransferase gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04350 SH03_RS04355 SH03_04350 SH03_RS04355 897769 898116 - PulS_OutS family protein gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04355 SH03_RS04360 SH03_04355 SH03_RS04360 898282 899832 + blue copper oxidase CueO laccase%3B copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04360 SH03_RS04365 SH03_04360 SH03_RS04365 900034 902424 - quinoprotein glucose dehydrogenase quinoprotein glucose dehydrogenase%3B catalyzes the formation of D-glucono-1%2C5-lactone from D-glucose and ubiquinone gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04365 SH03_RS04370 SH03_04365 SH03_RS04370 902630 903166 + hypoxanthine phosphoribosyltransferase catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04370 SH03_RS04375 SH03_04370 SH03_RS04375 903207 903869 - carbonic anhydrase catalyzes the interconversion of bicarbonate and carbon dioxide gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04375 SH03_RS04380 SH03_04375 SH03_RS04380 903978 904904 + ABC transporter ATPase gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04380 SH03_RS04385 SH03_04380 SH03_RS04385 904901 905671 + inner membrane transport permease YadH gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04385 SH03_RS04390 SH03_04385 SH03_RS04390 905776 906216 + PTS Enzyme IIA gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04390 SH03_RS04395 SH03_04390 SH03_RS04395 906280 907509 + polysaccharide deacetylase lipoprotein gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04395 SH03_RS04400 SH03_04395 SH03_RS04400 907513 907893 - aspartate 1-decarboxylase gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04400 SH03_RS04405 SH03_04400 SH03_RS04405 908167 909069 + transposase gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04405 SH03_RS04410 SH03_04405 panC panC 909143 909994 - pantothenate synthetase catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04410 SH03_RS04415 SH03_04410 panB panB 910006 910800 - 3-methyl-2-oxobutanoate hydroxymethyltransferase catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5%2C10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04415 SH03_RS04420 SH03_04415 SH03_RS04420 910914 912152 - fimbrial-like adhesin protein gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04420 SH03_RS04425 SH03_04420 SH03_RS04425 912202 912798 - fimbrial-like adhesin protein gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04425 SH03_RS04430 SH03_04425 SH03_RS04430 912825 913427 - fimbrial protein gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04430 SH03_RS04435 SH03_04430 SH03_RS04435 913442 914011 - fimbrial-like adhesin protein gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04435 SH03_RS04440 SH03_04435 SH03_RS04440 914028 916625 - outer membrane usher protein HtrE similar to the fimbrial usher protein PapC gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04440 SH03_RS04445 SH03_04440 ecpD ecpD 916660 917400 - fimbrial chaperone gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04445 SH03_RS04450 SH03_04445 SH03_RS04450 917498 918082 - fimbrial-like adhesin protein gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04450 SH03_RS04455 SH03_04450 SH03_RS04455 918452 918931 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine and ATP gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04455 SH03_RS04460 SH03_04455 pcnB pcnB 918928 920292 - poly(A) polymerase I Polymerase that creates the 3' poly(A) tail found in some mRNA's gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04460 SH03_RS04465 SH03_04460 SH03_RS04465 920385 921281 - glutamyl-Q tRNA(Asp) ligase this tRNA synthetase lacks the tRNA anticodon interaction domain%3B instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4%2C5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp%3B the modified tRNA does not bind elongation factor Tu gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04465 SH03_RS04470 SH03_04465 dksA dksA 921348 921803 - RNA polymerase-binding transcription factor DksA gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04470 SH03_RS04475 SH03_04470 SH03_RS04475 921981 922685 - sugar fermentation stimulation protein A gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04475 SH03_RS04480 SH03_04475 SH03_RS04480 922700 923230 - RNA 2'%2C3'-cyclic phosphodiesterase catalyzes the ligation and cleavage of of 2'-5' linkages in RNA gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04480 SH03_RS04485 SH03_04480 SH03_RS04485 923259 925733 + RNA helicase similar in sequence to the ATP-dependent RNA helicase HrpA gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04485 SH03_RS04490 SH03_04485 SH03_RS04490 925736 925942 + hypothetical protein gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04490 SH03_RS04495 SH03_04490 mrcB mrcB 925929 928463 + penicillin-binding protein 1B penicillin-binding protein 1b%3B contains transglycosylase and transpeptidase activity%3B major enzyme for peptidoglycan biosynthesis in Escherichia coli%3B transmembrane protein%3B forms dimers%3B three variants%2C one of which may be a degradation product%2C while the other appears to result from an alternative initiation site%2C are found within the cell gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04495 SH03_RS04500 SH03_04495 SH03_RS04500 928683 930926 + ferrichrome-iron receptor involved with the transport of ferrichrome across the outer membrane%3B binds the ferrichrome-iron ligand and interacts with the TonB protein gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04500 SH03_RS04505 SH03_04500 SH03_RS04505 930977 931774 + iron(3+)-hydroxamate import ATP-binding protein FhuC part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04505 SH03_RS04510 SH03_04505 SH03_RS04510 931774 932664 + iron(3+)-hydroxamate-binding protein FhuD Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter%3B binds to all hydroxamate siderophores gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04510 SH03_RS04515 SH03_04510 SH03_RS04515 932661 934643 + iron(3+)-hydroxamate import system permease FhuB gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04515 SH03_RS04520 SH03_04515 SH03_RS04520 934801 936081 - glutamate-1-semialdehyde 2%2C1-aminomutase Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04520 SH03_RS04525 SH03_04520 SH03_RS04525 936306 937727 + H+/Cl- exchange transporter ClcA Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04525 SH03_RS04530 SH03_04525 SH03_RS04530 937809 938153 + iron-sulfur cluster insertion protein ErpA essential respiratory protein A%3B may be involved in the transfer of iron-sulfur clusters%3B essential for growth using oxygen or alternate electron acceptors gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04530 SH03_RS04535 SH03_04530 SH03_RS04535 938200 938823 - hypothetical protein gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04535 SH03_RS04540 SH03_04535 SH03_RS04540 938861 939661 - vitamin B12-binding protein solute binding component of the vitamin B12 transport system BtuCDF gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04540 SH03_RS04545 SH03_04540 SH03_RS04545 939654 940352 - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04545 SH03_RS04550 SH03_04545 dgt dgt 940436 941953 + deoxyguanosinetriphosphate triphosphohydrolase forms a homotetramer%3B requires magnesium for activity%3B catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04550 SH03_RS04555 SH03_04550 SH03_RS04555 942083 943507 + periplasmic serine endoprotease DegP protease Do%3B required at high temperature%3B degrades damaged proteins gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04555 SH03_RS04560 SH03_04555 SH03_RS04560 943662 944819 + carbohydrate diacid regulator regulates the expression of the operons for the enzymes involved in galactarate%2C glucarate and glycerate utilization gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04560 SH03_RS04565 SH03_04560 SH03_RS04565 944908 945294 - hypothetical protein gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04565 SH03_RS04570 SH03_04565 SH03_RS04570 945456 946268 - phosphodiesterase YaeI gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04570 SH03_RS04575 SH03_04570 dapD dapD 946322 947146 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxylate N-succinyltransferase catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04575 SH03_RS04580 SH03_04575 SH03_RS04580 947177 949849 - uridylyltransferase catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04580 SH03_RS04585 SH03_04580 SH03_RS04585 949911 950705 - methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04585 SH03_RS04590 SH03_04585 SH03_RS04590 951073 951798 + 30S ribosomal protein S2 gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04590 SH03_RS04595 SH03_04590 tsf tsf 952056 952907 + elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04595 SH03_RS04600 SH03_04595 SH03_RS04600 953054 953779 + uridylate kinase gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04600 SH03_RS04605 SH03_04600 frr frr 954071 954628 + ribosome-recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04605 SH03_RS04610 SH03_04605 SH03_RS04610 954720 955916 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04610 SH03_RS04615 SH03_04610 SH03_RS04615 956105 956863 + UDP pyrophosphate synthase catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04615 SH03_RS04620 SH03_04615 cdsA cdsA 956876 957733 + phosphatidate cytidylyltransferase catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04620 SH03_RS04625 SH03_04620 SH03_RS04625 957745 959097 + inner membrane zinc RIP metalloprotease%3B RpoE activator%2C by degrading RseA%3B cleaved signal peptide endoprotease catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04625 SH03_RS04630 SH03_04625 SH03_RS04630 959127 961559 + outer membrane protein assembly factor BamA part of a complex with YfgL%2C YfiO%2C and NlpB involved in outer membrane protein biosynthesis%3B involved in the assembly of outer membrane proteins gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04630 SH03_RS04635 SH03_04630 SH03_RS04635 961681 962166 + chaperone protein Skp gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04635 SH03_RS04640 SH03_04635 lpxD lpxD 962170 963195 + UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04640 SH03_RS04645 SH03_04640 SH03_RS04645 963300 963755 + 3-hydroxyacyl-ACP dehydratase gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04645 SH03_RS04650 SH03_04645 SH03_RS04650 963759 964547 + acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04650 SH03_RS04655 SH03_04650 lpxB lpxB 964547 965695 + lipid-A-disaccharide synthase catalyzes the formation of lipid A disaccharide from UDP-2%2C3-diacylglucosamine and 2%2C3-diacylglucosamine-1-phosphate%2C lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04655 SH03_RS04660 SH03_04655 rnhB rnhB 965692 966288 + ribonuclease HII RNH2%3B RNase HII%3B binds manganese%3B endonuclease which specifically degrades the RNA of RNA-DNA hybrids gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04660 SH03_RS04665 SH03_04660 dnaE dnaE 966325 969807 + DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04665 SH03_RS04670 SH03_04665 SH03_RS04670 969820 970779 + acetyl-CoA carboxylase carboxyltransferase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04670 SH03_RS04675 SH03_04670 SH03_RS04675 970878 973019 + lysine decarboxylase constitutive constitutive%3B catalyzes the formation of cadaverine from lysine gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04675 SH03_RS04680 SH03_04675 SH03_RS04680 973076 973465 + lyase gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04680 SH03_RS04685 SH03_04680 tilS tilS 973530 974828 + tRNA(Ile)-lysidine synthase Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%3B ATP-dependent%3B responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04685 SH03_RS04690 SH03_04685 SH03_RS04690 974877 975137 - Rho-binding antiterminator Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04690 SH03_RS04695 SH03_04690 SH03_RS04695 975124 975324 - hypothetical protein gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04695 SH03_RS04700 SH03_04695 SH03_RS04700 975490 976035 + PDDEXK superfamily protein gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04700 SH03_RS04705 SH03_04700 SH03_RS04705 976032 976454 + peptidyl-tRNA hydrolase ArfB gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04705 SH03_RS04710 SH03_04705 SH03_RS04710 976468 977178 + lipoprotein NlpE gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04710 SH03_RS04715 SH03_04710 SH03_RS04715 977378 978202 - endopeptidase gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04715 SH03_RS04720 SH03_04715 SH03_RS04720 978256 979974 - proline--tRNA ligase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04720 SH03_RS04725 SH03_04720 SH03_RS04725 980086 980793 - tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04725 SH03_RS04730 SH03_04725 rcsF rcsF 980790 981194 - hypothetical protein gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04730 SH03_RS04735 SH03_04730 metQ metQ 981312 982127 - D-methionine-binding lipoprotein MetQ gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04735 SH03_RS04740 SH03_04735 SH03_RS04740 982167 982820 - methionine ABC transporter part of the MetNIQ methionine uptake system gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04740 SH03_RS04745 SH03_04740 metN metN 982813 983844 - methionine import ATP-binding protein MetN part of the metNIQ transport system for methionine gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04745 SH03_RS04750 SH03_04745 SH03_RS04750 984032 984607 + D-glycero-beta-D-manno-heptose-1%2C7-bisphosphate 7-phosphatase Converts the D-glycero-beta-D-manno-heptose 1%2C7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04750 SH03_RS04755 SH03_04750 SH03_RS04755 984968 986523 + 16S ribosomal RNA rRNA gene948 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04755 SH03_RS04760 SH03_04755 SH03_RS04760 986580 986656 + tRNA-Ile tRNA gene949 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04760 SH03_RS04765 SH03_04760 SH03_RS04765 986699 986774 + tRNA-Ala tRNA gene950 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04765 SH03_RS04770 SH03_04765 SH03_RS04770 986949 989878 + 23S ribosomal RNA rRNA gene951 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04770 SH03_RS04775 SH03_04770 SH03_RS04775 989957 990072 + 5S ribosomal RNA rRNA gene952 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04775 SH03_RS04780 SH03_04775 SH03_RS04780 990127 990203 + tRNA-Asp tRNA gene953 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04780 SH03_RS04785 SH03_04780 dkgB dkgB 990366 991169 + 2%2C5-diketo-D-gluconic acid reductase B catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04785 SH03_RS04790 SH03_04785 SH03_RS04790 991166 992080 - LysR family transcriptional regulator gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04790 SH03_RS04795 SH03_04790 SH03_RS04795 992321 993121 + endo/exonuclease/phosphatase gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04795 SH03_RS04800 SH03_04795 SH03_RS04800 993125 993748 + S-adenosyl-L-methionine-dependent methyltransferase gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04800 SH03_RS04805 SH03_04800 mltD mltD 993796 995154 - murein transglycosylase catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues%3B may play a role in recycling muropeptides during cell division and/or cell elongation%3B in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04805 SH03_RS04810 SH03_04805 SH03_RS04810 995226 995981 - hydroxyacylglutathione hydrolase catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione%3B plays an important role in cellular detoxification using glutathione gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04810 SH03_RS04815 SH03_04810 SH03_RS04815 996015 996737 + S-adenosyl-L-methionine-dependent methyltransferase gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04815 SH03_RS04820 SH03_04815 SH03_RS04820 996734 997201 - ribonuclease HI%2C degrades RNA of DNA-RNA hybrids gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04820 SH03_RS04825 SH03_04820 SH03_RS04825 997257 997997 + DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04825 SH03_RS04830 SH03_04825 SH03_RS04830 998130 998206 + tRNA-Asp tRNA gene963 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04830 SH03_RS04835 SH03_04830 SH03_RS04835 998534 999319 + lipoprotein gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04835 SH03_RS04840 SH03_04835 SH03_RS04840 999456 999935 - hypothetical protein gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04840 SH03_RS04845 SH03_04840 SH03_RS04845 999945 1000283 - hypothetical protein gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04845 SH03_RS04850 SH03_RS04850 SH03_RS04850 1000335 1000577 + transposase gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04850 SH03_RS04855 SH03_04850 SH03_RS04855 1000618 1001388 - hydrolase YafV NAD(P)-binding gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04855 SH03_RS04860 SH03_04855 SH03_RS04860 1001569 1002015 + hypothetical protein inactivates vertebrate C-type lysozyme gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04860 SH03_RS04865 SH03_04860 fadE fadE 1002058 1004502 - acyl-CoA dehydrogenase functions in fatty acid oxidation%3B converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04865 SH03_RS04870 SH03_04865 gmhA gmhA 1004742 1005320 + phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04870 SH03_RS04875 SH03_04870 SH03_RS04875 1005526 1006293 + glutamine amidotransferase gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04875 SH03_RS04880 SH03_04875 SH03_RS04880 1006264 1007004 - transpeptidase gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04880 SH03_RS04885 SH03_04880 SH03_RS04885 1007160 1007438 - mRNA interferase YafQ gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04885 SH03_RS04890 SH03_04885 SH03_RS04890 1007441 1007701 - antitoxin DinJ DNA-damage-inducible protein J%3B antitoxin of YafQ-DinJ toxin-antitoxin system gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04890 SH03_RS04895 SH03_04890 SH03_RS04895 1007911 1008660 + endopeptidase gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04895 SH03_RS04900 SH03_04895 SH03_RS04900 1008836 1009333 + transposase gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04900 SH03_RS04905 SH03_04900 SH03_RS04905 1009557 1011296 - flagellar biosynthesis protein FlhA gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04905 SH03_RS04910 SH03_04905 SH03_RS04910 1011256 1012026 + hypothetical protein gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04910 SH03_RS04915 SH03_04910 SH03_RS04915 1012097 1013152 + DNA polymerase IV involved in translesion DNA polymerization with beta clamp of polymerase III%3B belongs to Y family of polymerases%3B does not contain proofreading function gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04915 SH03_RS04920 SH03_04915 SH03_RS04920 1013204 1013497 + antitoxin YafN gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04920 SH03_RS04925 SH03_04920 SH03_RS04925 1013500 1013898 + mRNA interferase YafO YafO overproduction induces toxicity%3B it is believed to be the toxin of a toxin-antitoxin pair%3B unknown function gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04925 SH03_RS04930 SH03_04925 SH03_RS04930 1013986 1014360 + acyltransferase gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04930 SH03_RS04935 SH03_04930 SH03_RS04935 1014666 1014932 + hypothetical protein gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04935 SH03_RS04940 SH03_04935 prfH prfH 1014844 1015401 + peptide chain release factor similar to release factor 1 and 2 gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04940 SH03_RS04945 SH03_04940 SH03_RS04945 1015458 1016915 - cytosol non-specific dipeptidase catalyzes the hydrolysis of Xaa-His dipeptides gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04945 SH03_RS04950 SH03_04945 SH03_RS04950 1017176 1017634 + xanthine phosphoribosyltransferase catalyzes the conversion of guanine%2C xanthine and%2C to a lesser extent%2C hypoxanthine to GMP%2C XMP and IMP%2C respectively gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04950 SH03_RS04955 SH03_04950 frsA frsA 1017726 1018970 + esterase forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc%3B FrsA may promote fermentation gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04955 SH03_RS04960 SH03_04955 SH03_RS04960 1019028 1019429 + sigma factor-binding protein Crl involved in the expression of csgBA which is involved in curli formation%3B interacts with sigmaS gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04960 SH03_RS04965 SH03_04960 SH03_RS04965 1019468 1020523 - outer membrane pore protein E gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04965 SH03_RS04970 SH03_04965 SH03_RS04970 1020811 1021914 + glutamate 5-kinase gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04970 SH03_RS04975 SH03_04970 SH03_RS04975 1021926 1023179 + gamma-glutamyl phosphate reductase gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04975 SH03_RS04980 SH03_04975 SH03_RS04980 1023294 1023369 + tRNA-Thr tRNA gene993 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04980 SH03_RS04985 SH03_04980 SH03_RS04985 1023751 1024092 - toxin YkfI gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04985 SH03_RS04990 SH03_04985 SH03_RS04990 1024113 1024430 - antitoxin YafW gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04990 SH03_RS04995 SH03_04990 SH03_RS04995 1024679 1025155 - UPF0758 protein YkfG gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS04995 SH03_RS05000 SH03_04995 SH03_RS05000 1025171 1025629 - hypothetical protein gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05000 SH03_RS05005 SH03_05000 SH03_RS05005 1025727 1025966 - UPF0401 protein YkfF gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05005 SH03_RS05010 SH03_05005 SH03_RS05010 1026043 1026510 - hypothetical protein gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05010 SH03_RS05015 SH03_05010 SH03_RS05015 1026533 1026976 - lipoprotein%2C inner membrane%3B degP regulator%3B CP4-6 prophage gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05015 SH03_RS05020 SH03_05015 SH03_RS05020 1026976 1027215 - membrane protein gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05020 SH03_RS05025 SH03_05020 SH03_RS05025 1027607 1028428 - UPF0380 protein YafZ gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05025 SH03_RS05030 SH03_05025 SH03_RS05030 1028520 1029383 - hypothetical protein gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05030 SH03_RS05035 SH03_05030 SH03_RS05035 1029712 1030605 - transcriptional regulator gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05035 SH03_RS05040 SH03_05035 SH03_RS05040 1030701 1031069 + transposase gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05040 SH03_RS05045 SH03_05040 SH03_RS05045 1031026 1032177 + transposase gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05045 SH03_RS05050 SH03_05045 SH03_RS05050 1032253 1032678 + DNA-binding protein gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05050 SH03_RS05055 SH03_RS05055 SH03_RS05055 1032608 1032976 - hypothetical protein gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05055 SH03_RS05060 SH03_05055 SH03_RS05060 1032891 1033316 - hypothetical protein gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05060 SH03_RS05065 SH03_RS05065 SH03_RS05065 1033285 1034414 + hypothetical protein gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05065 SH03_RS05070 SH03_05065 SH03_RS05070 1034524 1035504 - transposase gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05070 SH03_RS05075 SH03_05070 SH03_RS05075 1035748 1037151 + S-methylmethionine permease gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05075 SH03_RS05080 SH03_05075 SH03_RS05080 1037138 1038070 + homocysteine S-methyltransferase gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05080 SH03_RS05085 SH03_05080 fbpC fbpC 1038179 1039225 - Fe(3+) ions import ATP-binding protein FbpC Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05085 SH03_RS05090 SH03_05085 SH03_RS05090 1039237 1039599 - iron ABC transporter permease gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05090 SH03_RS05095 SH03_05090 SH03_RS05095 1039601 1040104 - transposase gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05095 SH03_RS05100 SH03_05095 SH03_RS05100 1040023 1040298 - repressor TnpA gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05100 SH03_RS05105 SH03_05100 SH03_RS05105 1040447 1040785 - transposase gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05105 SH03_RS05110 SH03_05105 SH03_RS05110 1040808 1041158 - hypothetical protein gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05110 SH03_RS05115 SH03_05110 SH03_RS05115 1041252 1042394 - hypothetical protein gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05115 SH03_RS05120 SH03_05115 SH03_RS05120 1042701 1043609 + hypothetical protein gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05120 SH03_RS05125 SH03_05120 SH03_RS05125 1043624 1045591 + hypothetical protein gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05125 SH03_RS05130 SH03_05125 SH03_RS05130 1045818 1047200 + hypothetical protein uncharacterized member of the GPH family of galactose-pentose-hexuronide transporters gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05130 SH03_RS05135 SH03_05130 SH03_RS05135 1047212 1048822 + arabinosidase gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05135 SH03_RS05140 SH03_05135 SH03_RS05140 1048827 1049585 - transcriptional regulator gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05140 SH03_RS05145 SH03_05140 SH03_RS05145 1049724 1050728 - ornithine carbamoyltransferase chain F catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05145 SH03_RS05150 SH03_05145 SH03_RS05150 1051072 1051575 - transposase gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05150 SH03_RS05155 SH03_05150 SH03_RS05155 1051923 1052654 + hypothetical protein gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05155 SH03_RS05160 SH03_05155 SH03_RS05160 1052745 1053371 - hypothetical protein gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05160 SH03_RS05165 SH03_05160 SH03_RS05165 1053643 1054341 - hypothetical protein gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05165 SH03_RS05170 SH03_05165 SH03_RS05170 1054368 1055222 - hypothetical protein gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05170 SH03_RS05175 SH03_05170 SH03_RS05175 1055341 1055565 - hypothetical protein gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05175 SH03_RS05180 SH03_05175 SH03_RS05180 1055562 1056002 - hypothetical protein gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05180 SH03_RS05185 SH03_05180 SH03_RS05185 1056119 1057444 - preprotein translocase gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05185 SH03_RS05190 SH03_05185 SH03_RS05190 1057601 1057677 + tRNA-Thr tRNA gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05190 SH03_RS05195 SH03_05190 SH03_RS05195 1057804 1058214 - hypothetical protein gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05195 SH03_RS05200 SH03_05195 SH03_RS05200 1058193 1059149 - moco insertion factor for PaoABC aldehyde oxidoreductase gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05200 SH03_RS05205 SH03_05200 SH03_RS05205 1059159 1061357 - PaoABC aldehyde oxidoreductase Moco-containing subunit gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05205 SH03_RS05210 SH03_05205 SH03_RS05210 1061354 1062310 - PaoABC aldehyde oxidoreductase FAD-containing subunit gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05210 SH03_RS05215 SH03_05210 SH03_RS05215 1062307 1062996 - PaoABC aldehyde oxidoreductase 2Fe-2S subunit gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05215 SH03_RS05220 SH03_05215 SH03_RS05220 1063414 1064028 + hypothetical protein gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05220 SH03_RS05225 SH03_05220 SH03_RS05225 1064276 1064605 - ferredoxin gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05225 SH03_RS05230 SH03_05225 SH03_RS05230 1064918 1065628 - fimbrial chaperone EcpE gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05230 SH03_RS05235 SH03_05230 SH03_RS05235 1065597 1067240 - fimbria adhesin EcpD gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05235 SH03_RS05240 SH03_05235 SH03_RS05240 1067230 1069755 - usher protein EcpC gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05240 SH03_RS05245 SH03_05240 SH03_RS05245 1069781 1070449 - fimbrial chaperone EcpB gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05245 SH03_RS05250 SH03_05245 SH03_RS05250 1070507 1071094 - common pilus major fimbrillin subunit EcpA gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05250 SH03_RS05255 SH03_05250 SH03_RS05255 1071169 1071711 - LuxR family transcriptional regulator gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05255 SH03_RS05260 SH03_05255 SH03_RS05260 1072535 1072762 + hypothetical protein gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05260 SH03_RS05265 SH03_05260 rpmJ rpmJ 1072797 1072937 - 50S ribosomal protein L36 smallest protein in the large subunit%3B similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc%3B the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion%3B the proteins in this group do not have the motif gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05265 SH03_RS05270 SH03_05265 SH03_RS05270 1072937 1073200 - 50S ribosomal protein L31 type B gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05270 SH03_RS05275 SH03_05270 SH03_RS05275 1073564 1073665 - hypothetical protein gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05275 SH03_RS05280 SH03_05275 SH03_RS05280 1074780 1075667 + attachment protein gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05280 SH03_RS05285 SH03_05280 SH03_RS05285 1075714 1076013 + transposase gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05285 SH03_RS05290 SH03_05285 SH03_RS05290 1076010 1076876 + transposase gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05290 SH03_RS05295 SH03_05290 SH03_RS05295 1076873 1077559 - transcriptional regulator gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05295 SH03_RS05300 SH03_05295 SH03_RS05300 1078149 1078742 - protein RclC gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05300 SH03_RS05305 SH03_05300 SH03_RS05305 1078754 1078990 - reactive chlorine species (RCS) stress resistance periplasmic protein gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05305 SH03_RS05310 SH03_05305 SH03_RS05310 1079099 1080424 - pyridine nucleotide-disulfide oxidoreductase Involved in disulfide oxidoreductase activity and electron transport gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05310 SH03_RS05315 SH03_05310 SH03_RS05315 1080650 1081504 + transcriptional regulator gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05315 SH03_RS05320 SH03_05315 SH03_RS05320 1082031 1082750 + cysteine-rich LutA family protein%3B electron transport chain YkgEFG component gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05320 SH03_RS05325 SH03_05320 SH03_RS05325 1082761 1084188 + ferridoxin-like LutB family protein%3B electron transport chain YkgEFG component gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05325 SH03_RS05330 SH03_05325 SH03_RS05330 1084181 1084876 + LutC family protein%3B electron transport chain YkgEFG component gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05330 SH03_RS05335 SH03_05330 SH03_RS05335 1084950 1085072 - universal stress protein gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05335 SH03_RS05340 SH03_05335 SH03_RS05340 1085119 1085787 - hypothetical protein gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05340 SH03_RS05345 SH03_05340 SH03_RS05345 1086000 1087670 - oxygen-dependent choline dehydrogenase catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05345 SH03_RS05350 SH03_05345 SH03_RS05350 1087684 1089156 - NAD/NADP-dependent betaine aldehyde dehydrogenase gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05350 SH03_RS05355 SH03_05350 SH03_RS05355 1089170 1089757 - transcriptional regulator HTH-type%3B bet1%3B Repressor involved in choline regulation of the bet genes gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05355 SH03_RS05360 SH03_05355 SH03_RS05360 1089886 1091919 + choline transporter proton-motive-force-driven choline transporter gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05360 SH03_RS05365 SH03_05360 SH03_RS05365 1092289 1092474 - hypothetical protein gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05365 SH03_RS05370 SH03_05365 SH03_RS05370 1092794 1093882 + cyclic di-GMP phosphodiesterase YahA gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05370 SH03_RS05375 SH03_05370 SH03_RS05375 1093924 1094856 - DNA-bindng transcriptional regulator gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05375 SH03_RS05380 SH03_05375 SH03_RS05380 1094948 1095445 - hypothetical protein gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05380 SH03_RS05385 SH03_05380 SH03_RS05385 1095703 1096308 + transcriptional regulator gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05385 SH03_RS05390 SH03_05385 SH03_RS05390 1096348 1097211 + DUF2877 domain-containing protein gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05390 SH03_RS05395 SH03_05390 SH03_RS05395 1097201 1098748 + NAD(P)-binding succinyl-CoA synthase gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05395 SH03_RS05400 SH03_05395 SH03_RS05400 1098748 1100166 + DUF1116 domain-containing protein gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05400 SH03_RS05405 SH03_RS05405 SH03_RS05405 1100138 1100419 + hypothetical protein gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05405 SH03_RS05410 SH03_05405 SH03_RS05410 1100495 1101445 + carbamate kinase-like protein YahI gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05410 SH03_RS05415 SH03_05410 SH03_RS05415 1101455 1102837 + metallo-dependent hydrolase domain deaminase metallo-dependent hydrolase superfamily%3B deaminase with metallo-dependent hydrolase domain gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05415 SH03_RS05420 SH03_05415 SH03_RS05420 1103214 1104263 + aldehyde reductase YahK gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05420 SH03_RS05425 SH03_05420 SH03_RS05425 1104506 1105321 + hypothetical protein gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05425 SH03_RS05430 SH03_05425 SH03_RS05430 1105734 1105979 + hypothetical protein gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05430 SH03_RS05435 SH03_05430 SH03_RS05435 1105996 1106628 - membrane protein gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05435 SH03_RS05440 SH03_05435 SH03_RS05440 1106814 1107089 + periplasmic protein%2C function unknown%2C YhcN family gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05440 SH03_RS05445 SH03_05440 SH03_RS05445 1107187 1108773 - propionate catabolism operon regulatory protein PrpR sigma-54 dependent activator family protein%3B activates the prpBCDE operon gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05445 SH03_RS05450 SH03_05445 prpB prpB 1109012 1109902 + methylisocitrate lyase catalyzes the formation of pyruvate and succinate from 2-methylisocitrate gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05450 SH03_RS05455 SH03_05450 SH03_RS05455 1110342 1111511 + 2-methylcitrate synthase catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate%3B also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05455 SH03_RS05460 SH03_RS05460 prpD prpD 1111545 1112996 + 2-methylcitrate dehydratase functions in propionate metabolism%3B involved in isomerization of (2S%2C3S)-methylcitrate to (2R%2C3S)-methylisocitrate%3B also encodes minor aconitase or dehydratase activity%3B aconitase C gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05460 SH03_RS05465 SH03_05460 prpE prpE 1113036 1114922 + propionate--CoA ligase catalyzes the formation of propionyl-CoA using propionate as a substrate%3B PrpE from Ralstonia solanacearum can produce acetyl-%2C propionyl-%2C butyryl- and acrylyl-coenzyme A%2C and Salmonella enterica produces propionyl- and butyryl-coenzyme A%3B not expressed in Escherichia coli when grown on propionate/minimal media%3B ATP-dependent gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05465 SH03_RS05470 SH03_05465 codB codB 1115252 1116511 + cytosine permease gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05470 SH03_RS05475 SH03_05470 SH03_RS05475 1116501 1117784 + cytosine deaminase Catalyzes the deamination of cytosine to uracil and ammonia gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05475 SH03_RS05480 SH03_05475 SH03_RS05480 1118121 1119020 - transcriptional regulator controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05480 SH03_RS05485 SH03_05480 SH03_RS05485 1119129 1119788 + carbonic anhydrase gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05485 SH03_RS05490 SH03_05485 SH03_RS05490 1119819 1120289 + cyanate hydratase gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05490 SH03_RS05495 SH03_05490 cynX cynX 1120295 1121476 + MFS transporter MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon%3B not essential gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05495 SH03_RS05500 SH03_05495 lacA lacA 1121579 1122190 - galactoside O-acetyltransferase transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides%3B exact physiological role is unknown gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05500 SH03_RS05505 SH03_05500 lacY lacY 1122256 1123509 - lactose permease lactose/proton symporter%3B mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides%3B member of major facilitator superfamily%3B functions as a monomer with 12 transmembrane segments gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05505 SH03_RS05510 SH03_05505 lacZ lacZ 1123561 1126635 - beta-galactosidase forms a homotetramer%3B hydrolyzes lactose disaccharide to galactose and glucose%3B converts lactose to allolactose which is the natural inducer of the lac operon gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05510 SH03_RS05515 SH03_05510 lacI lacI 1126758 1127717 - lac repressor transcriptional repressor of lac operon%3B forms a homotetramer as a dimer of dimers%3B binds specific sites in lac operon resulting in DNA looping between the operators%3B binds allolactose as inducer gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05515 SH03_RS05520 SH03_05515 SH03_RS05520 1127917 1128750 - mhp operon transcriptional activator activator of 3-phenylpropionic acid catabolism gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05520 SH03_RS05525 SH03_05520 mhpA mhpA 1128941 1130605 + 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase catalyzes the formation of 3-(2%2C3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05525 SH03_RS05530 SH03_05525 mhpB mhpB 1130607 1131551 + 2%2C3-dihydroxyphenylpropionate/2%2C3-dihydroxicinnamic acid 1%2C2-dioxygenase catalyzes the cleavage of 3-(2%2C3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2%2C4-diene-1%2C9-dioate%3B part of the 3-phenylpropionic acid degradation pathway%3B member of the protocatechuate 4%2C5-dioxygenase family gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05530 SH03_RS05535 SH03_05530 SH03_RS05535 1131569 1132435 + 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05535 SH03_RS05540 SH03_05535 SH03_RS05540 1132445 1133254 + 2-keto-4-pentenoate hydratase gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05540 SH03_RS05545 SH03_05540 SH03_RS05545 1133251 1134201 + acetaldehyde dehydrogenase catalyzes the formation of acetyl-CoA from acetalaldehyde gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05545 SH03_RS05550 SH03_05545 SH03_RS05550 1134198 1135211 + 4-hydroxy-2-oxovalerate aldolase catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid%3B involved in the degradation of phenylpropionate gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05550 SH03_RS05555 SH03_05550 SH03_RS05555 1135789 1137000 + 3-(3-hydroxy-phenyl)propionate transporter gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05555 SH03_RS05560 SH03_05555 SH03_RS05560 1137102 1137641 + DUF2058 domain-containing protein gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05560 SH03_RS05565 SH03_05560 SH03_RS05565 1137865 1138698 - S-formylglutathione hydrolase FrmB gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05565 SH03_RS05570 SH03_05565 SH03_RS05570 1138792 1139901 - S-(hydroxymethyl)glutathione dehydrogenase catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione%3B also catalyzes the formation of aldehyde or ketone from alcohols gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05570 SH03_RS05575 SH03_05570 SH03_RS05575 1139936 1140211 - transcriptional regulator formaldehyde-induced negative regulator of the frmRAB operon gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05575 SH03_RS05580 SH03_05575 SH03_RS05580 1140399 1141172 - outer membrane protein gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05580 SH03_RS05585 SH03_05580 SH03_RS05585 1141174 1141617 - transferase gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05585 SH03_RS05590 SH03_05585 SH03_RS05590 1141681 1142046 + transposase represses IS2 gene transcription gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05590 SH03_RS05595 SH03_05590 SH03_RS05595 1142004 1142909 + integrase gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05595 SH03_RS05600 SH03_05595 SH03_RS05600 1143069 1144265 - family 2 glycosyltransferase gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05600 SH03_RS05605 SH03_05600 SH03_RS05605 1144389 1144946 - PIG-L family deacetylase gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05605 SH03_RS05610 SH03_05605 tauA tauA 1145562 1146524 + taurine-binding periplasmic protein with TauB and TauC is responsible for taurine uptake. gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05610 SH03_RS05615 SH03_05610 tauB tauB 1146537 1147304 + taurine import ATP-binding protein TauB Part of the ABC transporter complex tauABC involved in taurine import gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05615 SH03_RS05620 SH03_05615 SH03_RS05620 1147301 1148128 + taurine ABC transporter permease gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05620 SH03_RS05625 SH03_05620 tauD tauD 1148125 1148976 + alpha-ketoglutarate-dependent taurine dioxygenase catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide%3B non-heme iron oxidase%3B allows the use of taurine as an alternative sulfur source%3B forms homodimers gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05625 SH03_RS05630 SH03_05625 SH03_RS05630 1149083 1150057 - delta-aminolevulinic acid dehydratase gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05630 SH03_RS05635 SH03_05630 SH03_RS05635 1150227 1150478 - hypothetical protein gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05635 SH03_RS05640 SH03_RS05640 SH03_RS05640 1150581 1152107 + pertactin gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05640 SH03_RS05645 SH03_05640 SH03_RS05645 1152069 1152935 - transposase gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05645 SH03_RS05650 SH03_05645 SH03_RS05650 1152932 1153231 - transposase gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05650 SH03_RS05655 SH03_RS05655 SH03_RS05655 1153306 1154748 + pertactin gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05655 SH03_RS05660 SH03_05655 SH03_RS05660 1154836 1155459 + transcriptional regulator gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05660 SH03_RS05665 SH03_05660 SH03_RS05665 1155460 1156617 - D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH this protein has no known enzymatic function gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05665 SH03_RS05670 SH03_05665 SH03_RS05670 1156755 1156949 + hypothetical protein gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05670 SH03_RS05675 SH03_05670 SH03_RS05675 1156969 1158189 + peptide antibiotic transporter SbmA in Escherichia coli SbmA is involved in uptake of microcin J25%3B functions along with FhuA%2C TonB%2C and ExbB/D in this capacity%3B in Sinorhizobium meliloti%2C BacA is essential and required for symbiosis%3B defects appear to affect the cell envelope gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05675 SH03_RS05680 SH03_05675 SH03_RS05680 1158202 1159296 + microcin transporter gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05680 SH03_RS05685 SH03_05680 SH03_RS05685 1159355 1159663 - hypothetical protein gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05685 SH03_RS05690 SH03_05685 SH03_RS05690 1159923 1160135 + DUF2754 domain-containing protein gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05690 SH03_RS05695 SH03_05690 SH03_RS05695 1160159 1161253 - D-alanine--D-alanine ligase A gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05695 SH03_RS05700 SH03_05695 SH03_RS05700 1161334 1161534 + hypothetical protein gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05700 SH03_RS05705 SH03_05700 SH03_RS05705 1161716 1161976 + anti-adapter protein IraP RpoS stabilzer during Pi starvation%3B anti-adapter protein gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05705 SH03_RS05710 SH03_05705 SH03_RS05710 1162077 1163492 + alkaline phosphatase gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05710 SH03_RS05715 SH03_05710 SH03_RS05715 1163611 1163931 + phosphate starvation-inducible protein PsiF gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05715 SH03_RS05720 SH03_05715 adrA adrA 1164033 1165148 + diguanylate cyclase catalyzes the conversion of 2 GTP into c-di-GMP%3B adrA overexpression induces cellulose biosynthesis%2C cell adherence to abiotic surfaces and swimming and swarming motility%3B AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05720 SH03_RS05725 SH03_05720 SH03_RS05725 1165165 1165974 - pyrroline-5-carboxylate reductase catalyzes the formation of L-proline from pyrroline-5-carboxylate gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05725 SH03_RS05730 SH03_05725 SH03_RS05730 1166094 1166552 + hypothetical protein gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05730 SH03_RS05735 SH03_05730 aroL aroL 1166735 1167259 + shikimate kinase type II enzyme similar to type I but differentially regulated and with a lower Km%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05735 SH03_RS05740 SH03_05735 SH03_RS05740 1167309 1167500 + hypothetical protein gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05740 SH03_RS05745 SH03_05740 SH03_RS05745 1167531 1167728 + hypothetical protein gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05745 SH03_RS05750 SH03_05745 SH03_RS05750 1167758 1168435 + protein AroM gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05750 SH03_RS05755 SH03_05750 SH03_RS05755 1168507 1168791 + hypothetical protein gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05755 SH03_RS05760 SH03_05755 SH03_RS05760 1168999 1169280 + hypothetical protein gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05760 SH03_RS05765 SH03_05760 SH03_RS05765 1169438 1170349 - recombination-associated protein RdgC Required for efficient pilin antigenic variation gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05765 SH03_RS05770 SH03_05765 SH03_RS05770 1170474 1171382 + fructokinase catalyzes phosphorylation of fructose%3B cytosolic enzyme gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05770 SH03_RS05775 SH03_05770 SH03_RS05775 1171627 1172811 - protein AraJ member of the major facilitator superfamily (MFS) of transporters%3B unknown function%3B may be associated with transport or processing of arabinose polymers gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05775 SH03_RS05780 SH03_05775 SH03_RS05780 1172937 1176083 - nuclease SbcCD subunit C with SbcD cleaves DNA hairpin structures%3B also has 5' single-strand endonuclease activity gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05780 SH03_RS05785 SH03_05780 SH03_RS05785 1176080 1177282 - nuclease SbcCD subunit D with SbcC cleaves DNA hairpin structure%2C also has 5' single-strand endonuclease activity gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05785 SH03_RS05790 SH03_05785 SH03_RS05790 1177472 1178161 + two-component system response regulator two component response regulator for the phosphate regulon%3B PhoR phosphorylates PhoB gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05790 SH03_RS05795 SH03_05790 phoR phoR 1178219 1179514 + phosphate regulon sensor protein PhoR membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05795 SH03_RS05800 SH03_05795 SH03_RS05800 1179921 1181240 + branched-chain amino acid transport system 2 carrier protein sodium:branched-chain amino acid symporter gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05800 SH03_RS05805 SH03_05800 proY proY 1181316 1182689 + proline-specific permease ProY cryptic permease that may be involved in the transport of proline across the inner membrane%3B in Salmonella typhimurium%2C the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05805 SH03_RS05810 SH03_05805 SH03_RS05810 1182845 1184662 + maltodextrin glucosidase gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05810 SH03_RS05815 SH03_05810 SH03_RS05815 1184667 1185248 - ACP phosphodiesterase Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05815 SH03_RS05820 SH03_05815 queA queA 1185341 1186411 + S-adenosylmethionine:tRNA ribosyltransferase-isomerase Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05820 SH03_RS05825 SH03_05820 tgt tgt 1186467 1187594 + queuine tRNA-ribosyltransferase Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr) gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05825 SH03_RS05830 SH03_05825 yajC yajC 1187617 1187949 + preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05830 SH03_RS05835 SH03_05830 secD secD 1187977 1189824 + preprotein translocase subunit SecD part of the preprotein secretory system%3B when complexed with proteins SecF and YajC%2C SecDFyajC stimulates the proton motive force-driven protein translocation%2C and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05835 SH03_RS05840 SH03_05835 SH03_RS05840 1189835 1190806 + protein translocase subunit SecF gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05840 SH03_RS05845 SH03_05840 SH03_RS05845 1190935 1191282 + hypothetical protein gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05845 SH03_RS05850 SH03_05845 SH03_RS05850 1191296 1191418 + hypothetical protein gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05850 SH03_RS05855 SH03_05850 SH03_RS05855 1191459 1192343 - nucleoside-specific channel-forming protein tsx receptor of phage T6 and colicin K%3B involved in the transfer of deoxyribo- and ribo-nucleotides across the outer membrane gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05855 SH03_RS05860 SH03_05855 SH03_RS05860 1192642 1193181 - lipoprotein gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05860 SH03_RS05865 SH03_05860 SH03_RS05865 1193332 1193781 + NrdR family transcriptional regulator gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05865 SH03_RS05870 SH03_05865 ribD ribD 1193785 1194888 + riboflavin biosynthesis protein RibD riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway%3B catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05870 SH03_RS05875 SH03_05870 ribH ribH 1194977 1195447 + 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05875 SH03_RS05880 SH03_05875 nusB nusB 1195467 1195886 + transcription antitermination protein NusB Regulates rRNA biosynthesis by transcriptional antitermination gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05880 SH03_RS05885 SH03_05880 SH03_RS05885 1195964 1196941 + thiamine-monophosphate kinase catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05885 SH03_RS05890 SH03_05885 SH03_RS05890 1196919 1197437 + phosphatidylglycerophosphatase A hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05890 SH03_RS05895 SH03_05890 SH03_RS05895 1197491 1198465 - 2-carboxybenzaldehyde reductase gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05895 SH03_RS05900 SH03_05895 SH03_RS05900 1198645 1200507 - 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05900 SH03_RS05905 SH03_05900 SH03_RS05905 1200532 1201431 - farnesyl-diphosphate synthase gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05905 SH03_RS05910 SH03_05905 SH03_RS05910 1201431 1201673 - exodeoxyribonuclease 7 small subunit catalyzes the bidirectional exonucleolytic cleavage of DNA gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05910 SH03_RS05915 SH03_05910 SH03_RS05915 1201879 1203327 + tRNA sulfurtransferase catalyzes the conversion of uridine to 4-thiouridinine tRNA%3B also required for the synthesis of the thiazole moiety gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05915 SH03_RS05920 SH03_05915 SH03_RS05920 1203381 1203971 - hypothetical protein gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05920 SH03_RS05925 SH03_05920 SH03_RS05925 1203934 1204845 - 2-dehydropantoate 2-reductase ketopantoate reductase%3B catalyzes the NADPH reduction of ketopantoate to pantoate%3B functions in pantothenate (vitamin B5) biosynthesis gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05925 SH03_RS05930 SH03_05925 SH03_RS05930 1205013 1205504 + nucleotide-binding protein nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ%3B the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05930 SH03_RS05935 SH03_05930 SH03_RS05935 1205632 1206996 - transporter gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05935 SH03_RS05940 SH03_05935 SH03_RS05940 1207145 1208035 - protoheme IX farnesyltransferase converts protoheme IX and farnesyl diphosphate to heme O gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05940 SH03_RS05945 SH03_05940 SH03_RS05945 1208047 1208376 - cytochrome bo(3) ubiquinol oxidase subunit 4 gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05945 SH03_RS05950 SH03_05945 SH03_RS05950 1208376 1208990 - cytochrome bo(3) ubiquinol oxidase subunit 3 gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05950 SH03_RS05955 SH03_05950 SH03_RS05955 1208980 1210971 - cytochrome bo(3) ubiquinol oxidase subunit 1 gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05955 SH03_RS05960 SH03_05955 SH03_RS05960 1210993 1211940 - cytochrome bo(3) ubiquinol oxidase subunit 2 gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05960 SH03_RS05965 SH03_05960 ampG ampG 1212400 1213875 - muropeptide MFS transporter AmpG in Escherichia coli this protein is a permease involved in peptidoglycan recycling%3B member of major facilitator superfamily%3B MFS%3B inner membrane protein gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05965 SH03_RS05970 SH03_05965 SH03_RS05970 1213919 1214497 - hypothetical protein gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05970 SH03_RS05975 SH03_05970 SH03_RS05975 1214802 1215119 + protein BolA positive transcriptional regulator of morphogenetic pathway%3B controlling several genes involved in oxidative stress%2C acid stress%2C heat shock%2C osmotic shock%2C and carbon-starvation stress gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05975 SH03_RS05980 SH03_05975 SH03_RS05980 1215128 1215316 + hypothetical protein gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05980 SH03_RS05985 SH03_05980 SH03_RS05985 1215463 1216761 + trigger factor gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05985 SH03_RS05990 SH03_05985 SH03_RS05990 1217007 1217630 + ATP-dependent Clp protease proteolytic subunit gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05990 SH03_RS05995 SH03_05990 clpX clpX 1217756 1219030 + ATP-dependent Clp protease ATP-binding subunit ClpX binds and unfolds substrates as part of the ClpXP protease gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS05995 SH03_RS06000 SH03_05995 SH03_RS06000 1219218 1221572 + lon protease gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06000 SH03_RS06005 SH03_06000 SH03_RS06005 1221781 1222053 + DNA-binding protein HU-beta histone-like DNA-binding protein gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06005 SH03_RS06010 SH03_06005 SH03_RS06010 1222245 1224116 + peptidyl-prolyl cis-trans isomerase gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06010 SH03_RS06015 SH03_06010 SH03_RS06015 1224267 1224638 + hypothetical protein gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06015 SH03_RS06020 SH03_06015 SH03_RS06020 1224732 1225130 + long-chain acyl-CoA thioesterase FadM gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06020 SH03_RS06025 SH03_06020 SH03_RS06025 1225182 1225877 - 7-cyano-7-deazaguanine synthase YbaX%3B catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0)%2C as one of the early reactions of quenosine biosynthesis%3B quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn%2C Asp%2C Tyr%2C and His gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06025 SH03_RS06030 SH03_06025 SH03_RS06030 1225942 1227642 - ABC transporter substrate-binding protein gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06030 SH03_RS06035 SH03_06030 SH03_RS06035 1227742 1228560 + HMP-PP phosphatase HMP-PP phosphatase%3B catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06035 SH03_RS06040 SH03_06035 SH03_RS06040 1228713 1229171 + transcriptional regulator gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06040 SH03_RS06045 SH03_06040 SH03_RS06045 1229201 1230973 + multidrug resistance-like ATP-binding protein MdlA gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06045 SH03_RS06050 SH03_06045 SH03_RS06050 1230966 1232747 + multidrug resistance-like ATP-binding protein MdlB gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06050 SH03_RS06055 SH03_06050 SH03_RS06055 1232928 1233266 + nitrogen regulatory protein P-II 2 indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06055 SH03_RS06060 SH03_06055 SH03_RS06060 1233296 1234582 + ammonia channel gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06060 SH03_RS06065 SH03_06060 SH03_RS06065 1234631 1235491 - acyl-CoA thioesterase 2 gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06065 SH03_RS06070 SH03_06065 SH03_RS06070 1235709 1236281 + hypothetical protein gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06070 SH03_RS06075 SH03_06070 SH03_RS06075 1236312 1236623 - methylated-DNA--protein-cysteine methyltransferase gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06075 SH03_RS06080 SH03_06075 SH03_RS06080 1237002 1237355 + DUF1428 domain-containing protein gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06080 SH03_RS06085 SH03_06080 SH03_RS06085 1237397 1238947 - cyclic-di-GMP phosphodiesterase gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06085 SH03_RS06090 SH03_06085 SH03_RS06090 1239111 1239581 - hypothetical protein gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06090 SH03_RS06095 SH03_06090 SH03_RS06095 1239697 1240248 - maltose O-acetyltransferase gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06095 SH03_RS06100 SH03_06095 SH03_RS06100 1240420 1240638 - transcriptional regulator with Hns involved in transcriptional regulation of hemolysin%3B non-specific DNA-binding protein which affects the production of multiple proteins gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06100 SH03_RS06105 SH03_06100 SH03_RS06105 1240664 1241038 - Hha toxicity modulator TomB gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06105 SH03_RS06110 SH03_06105 SH03_RS06110 1241584 1244733 - multidrug efflux RND transporter permease subunit gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06110 SH03_RS06115 SH03_06110 SH03_RS06115 1244756 1245949 - MexE family multidrug efflux RND transporter periplasmic adaptor subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06115 SH03_RS06120 SH03_06115 SH03_RS06120 1246091 1246738 + transcriptional regulator regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06120 SH03_RS06125 SH03_06120 SH03_RS06125 1246866 1250228 + mechanosensitive channel MscK gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06125 SH03_RS06130 SH03_06125 SH03_RS06130 1250266 1250406 - hypothetical protein gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06130 SH03_RS06135 SH03_06130 SH03_RS06135 1250440 1250601 - DUF2496 domain-containing protein gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06135 SH03_RS06140 SH03_06135 SH03_RS06140 1250615 1251142 - primosomal replication protein N'' PriC%3B protein involved in DNA replication%3B part of the primosome%2C a protein complex required to restart stalled replication forks%3B binds the complex formed by PriA%2C PriB and DNA%3B PriC-dependent primosome requires a gap to restart DNA replication%3B stimulates Rep activity at stalled forks gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06140 SH03_RS06145 SH03_06140 SH03_RS06145 1251212 1251589 + hypothetical protein gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06145 SH03_RS06150 SH03_06145 SH03_RS06150 1251742 1252293 + adenine phosphoribosyltransferase catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06150 SH03_RS06155 SH03_06150 SH03_RS06155 1252422 1254353 + DNA polymerase III subunit tau catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the tau chain serves as a scaffold to help in the dimerizaton of the alpha%2Cepsilon and theta core complex%3B the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06155 SH03_RS06160 SH03_06155 SH03_RS06160 1254406 1254735 + nucleoid-associated protein gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06160 SH03_RS06165 SH03_06160 recR recR 1254735 1255340 + recombination protein RecR involved in a recombinational process of DNA repair%2C independent of the recBC complex gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06165 SH03_RS06170 SH03_06165 SH03_RS06170 1255450 1257324 + chaperone protein HtpG molecular chaperone gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06170 SH03_RS06175 SH03_06170 adk adk 1257505 1258149 + adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06175 SH03_RS06180 SH03_06175 SH03_RS06180 1258385 1259347 + ferrochelatase gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06180 SH03_RS06185 SH03_06180 SH03_RS06185 1259344 1260303 - acetyl esterase gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06185 SH03_RS06190 SH03_06185 SH03_RS06190 1260455 1261759 + inosine-guanosine kinase catalyzes the formation of inosine/guanosine monophosphate from inosine or guanosine and ATP gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06190 SH03_RS06195 SH03_06190 SH03_RS06195 1261892 1263568 - hypothetical protein YbaL%3B member of the CPA-2 family of antiporters%3B uncharacterized protein gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06195 SH03_RS06200 SH03_06195 SH03_RS06200 1263806 1265026 - fosmidomycin resistance protein gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06200 SH03_RS06205 SH03_06200 ushA ushA 1265244 1266896 + protein UshA catalyzes the degradation of periplasmic UDP-glucose to uridine%2C glucose-1-phosphate and inorganic phosphate%3B specific for uridine nucleotides gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06205 SH03_RS06210 SH03_06205 SH03_RS06210 1266933 1267412 - cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06210 SH03_RS06215 SH03_06210 SH03_RS06215 1267616 1268410 - TraB family protein gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06215 SH03_RS06220 SH03_06215 SH03_RS06220 1268548 1268889 + transcriptional regulator gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06220 SH03_RS06225 SH03_06220 copA copA 1269205 1271709 - copper-exporting P-type ATPase A gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06225 SH03_RS06230 SH03_06225 SH03_RS06230 1271971 1272903 + glutaminase 1 catalyzes the formation of glutamate from glutamine gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06230 SH03_RS06235 SH03_06230 SH03_RS06235 1272906 1274198 + transporter gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06235 SH03_RS06240 SH03_06235 SH03_RS06240 1274323 1274730 + transcriptional regulator activator of copper-responsive regulon genes gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06240 SH03_RS06245 SH03_06240 SH03_RS06245 1274731 1275189 - hypothetical protein gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06245 SH03_RS06250 SH03_06245 SH03_RS06250 1275186 1276103 - protein QmcA gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06250 SH03_RS06255 SH03_06250 SH03_RS06255 1276249 1276926 + iron export ATP-binding protein FetA gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06255 SH03_RS06260 SH03_06255 SH03_RS06260 1276913 1277692 + iron export permease FetB gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06260 SH03_RS06265 SH03_06260 SH03_RS06265 1277755 1278609 - molecular chaperone DnaK gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06265 SH03_RS06270 SH03_06265 SH03_RS06270 1278670 1279440 - oxidoreductase gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06270 SH03_RS06275 SH03_06270 SH03_RS06275 1279469 1280092 - multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06275 SH03_RS06280 SH03_06275 SH03_RS06280 1280063 1280749 + ABC transporter ATP-binding protein gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06280 SH03_RS06285 SH03_06280 SH03_RS06285 1280746 1283160 + ABC transporter permease gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06285 SH03_RS06290 SH03_06285 SH03_RS06290 1283591 1287871 + RHS element protein gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06290 SH03_RS06295 SH03_06290 SH03_RS06295 1287911 1288279 + immunity protein gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06295 SH03_RS06300 SH03_06295 SH03_RS06300 1288279 1288989 + hypothetical protein gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06300 SH03_RS06305 SH03_06300 SH03_RS06305 1288970 1289230 + hypothetical protein gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06305 SH03_RS06310 SH03_06305 SH03_RS06310 1289975 1290346 - hypothetical protein gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06310 SH03_RS06315 SH03_06310 SH03_RS06315 1290462 1291556 - tRNA 2-selenouridine synthase catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06315 SH03_RS06320 SH03_06315 SH03_RS06320 1291625 1292551 - HTH-type transcriptional activator AllS activator of the allDC-ylbA operon involved in allantoin utilization gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06320 SH03_RS06325 SH03_06320 SH03_RS06325 1292781 1293263 + ureidoglycolate lyase gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06325 SH03_RS06330 SH03_06325 SH03_RS06330 1293341 1294156 + transcriptional regulator regulates operons involved in the utilization of allantoin gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06330 SH03_RS06335 SH03_06330 SH03_RS06335 1294246 1296027 + glyoxylate carboligase catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06335 SH03_RS06340 SH03_06335 SH03_RS06340 1296040 1296816 + hydroxypyruvate isomerase gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06340 SH03_RS06345 SH03_06340 SH03_RS06345 1296916 1297794 + 2-hydroxy-3-oxopropionate reductase NADH-dependent%3B catalyzed the reversible formation of glycerate from tartronate semialdehyde gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06345 SH03_RS06350 SH03_06345 SH03_RS06350 1297963 1299417 + allantoin transporter gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06350 SH03_RS06355 SH03_06350 SH03_RS06355 1299477 1300838 + allantoinase Plays a crucial role on both purine and pyrimidine metabolism gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06355 SH03_RS06360 SH03_06355 SH03_RS06360 1300895 1302196 + uracil/xanthine transporter gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06360 SH03_RS06365 SH03_06360 SH03_RS06365 1302218 1303363 + glycerate kinase gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06365 SH03_RS06370 SH03_06365 SH03_RS06370 1303591 1304376 - (S)-ureidoglycine aminohydrolase gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06370 SH03_RS06375 SH03_06370 SH03_RS06375 1304387 1305622 - allantoate amidohydrolase gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06375 SH03_RS06380 SH03_06375 SH03_RS06380 1305644 1306693 - ureidoglycolate dehydrogenase (NAD+) catalyzes the formation of oxalurate from ureidoglycolate gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06380 SH03_RS06385 SH03_06380 SH03_RS06385 1307010 1308677 + protein FdrA multicopy suppressor of dominant negative ftsH mutations%3B putative acyl-CoA synthetase gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06385 SH03_RS06390 SH03_06385 SH03_RS06390 1308687 1309946 + DUF1116 domain-containing protein gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06390 SH03_RS06395 SH03_06390 SH03_RS06395 1309957 1310772 + anaerobic allantoin catabolic oxamate carbamoyltransferase%3B DUF2877 family protein gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06395 SH03_RS06400 SH03_06395 SH03_RS06400 1310769 1311662 + carbamate kinase reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06400 SH03_RS06405 SH03_06400 SH03_RS06405 1311857 1312924 - N5-carboxyaminoimidazole ribonucleotide synthase gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06405 SH03_RS06410 SH03_06405 purE purE 1312921 1313430 - N5-carboxyaminoimidazole ribonucleotide mutase catalyzes the formation of 4-carboxy-5-aminoimidazole ribonucleotide from N5-carboxyaminoimidazole ribonucleotide gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06410 SH03_RS06415 SH03_06410 SH03_RS06415 1313548 1314270 - UDP-2%2C3-diacylglucosamine hydrolase catalyzes the formation of 2%2C3%3Ddiacylglucosamine 1-phosphate from UDP-2%2C3%3Ddiacylglucosamine gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06415 SH03_RS06420 SH03_06415 SH03_RS06420 1314273 1314767 - peptidyl-prolyl cis-trans isomerase gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06420 SH03_RS06425 SH03_06420 cysS cysS 1314941 1316326 + cysteine--tRNA ligase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06425 SH03_RS06430 SH03_06425 SH03_RS06430 1316362 1316883 - hypothetical protein gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06430 SH03_RS06435 SH03_06430 SH03_RS06435 1316991 1317203 - ribosome-associated protein gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06435 SH03_RS06440 SH03_06435 SH03_RS06440 1317205 1318071 - bifunctional protein FolD gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06440 SH03_RS06445 SH03_06440 SH03_RS06445 1318542 1319084 + FimA homolog%2C function unknown gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06445 SH03_RS06450 SH03_06445 SH03_RS06450 1319304 1319996 + fimbrial chaperone SfmC gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06450 SH03_RS06455 SH03_06450 SH03_RS06455 1320027 1322630 + outer membrane usher protein SfmD gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06455 SH03_RS06460 SH03_06455 fimH fimH 1322672 1323649 + adhesin involved in the regulation of fimbriae length and mediates adhesion of type 1 fimbriae gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06460 SH03_RS06465 SH03_06460 SH03_RS06465 1323660 1324175 + FimA homolog%2C function unknown gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06465 SH03_RS06470 SH03_06465 SH03_RS06470 1324178 1324810 - fimbriae Z protein activates the production of the major fimbrae protein FimA gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06470 SH03_RS06475 SH03_06470 SH03_RS06475 1325053 1325129 + tRNA-Arg tRNA gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06475 SH03_RS06480 SH03_06475 SH03_RS06480 1325145 1326308 - integrase gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06480 SH03_RS06485 SH03_06480 SH03_RS06485 1326428 1326691 - exonuclease gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06485 SH03_RS06490 SH03_06485 SH03_RS06490 1326781 1327017 + replication protein gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06490 SH03_RS06495 SH03_06490 SH03_RS06495 1327014 1327109 + hypothetical protein gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06495 SH03_RS06500 SH03_06495 SH03_RS06500 1327172 1327471 + transposase gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06500 SH03_RS06505 SH03_06500 SH03_RS06505 1327468 1328334 + transposase gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06505 SH03_RS06510 SH03_RS06510 SH03_RS06510 1328365 1328577 + protein ren gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06510 SH03_RS06515 SH03_06510 SH03_RS06515 1328645 1328977 + multidrug SMR transporter gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06515 SH03_RS06520 SH03_06515 SH03_RS06520 1329025 1329174 + membrane protein gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06520 SH03_RS06525 SH03_06520 SH03_RS06525 1329232 1330758 + DLP12 prophage%3B recombinase gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06525 SH03_RS06530 SH03_06525 SH03_RS06530 1331223 1331774 + hypothetical protein gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06530 SH03_RS06535 SH03_06530 SH03_RS06535 1331784 1332581 + transcriptional regulator gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06535 SH03_RS06540 SH03_06535 SH03_RS06540 1332796 1333251 + DLP12 prophage%3B uncharacterized protein DLP12 prophage gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06540 SH03_RS06545 SH03_06540 SH03_RS06545 1333251 1333421 + protein NinE from lambdoid prophage DLP12 DLP12 prophage%3B conserved protein similar to phage 82 and lambda proteins gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06545 SH03_RS06550 SH03_06545 SH03_RS06550 1333414 1333704 + DLP12 prophage%3B uncharacterized protein gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06550 SH03_RS06555 SH03_06550 SH03_RS06555 1333701 1334063 + crossover junction endodeoxyribonuclease RusA gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06555 SH03_RS06560 SH03_06555 SH03_RS06560 1334060 1334200 + protein%2C DLP12 prophage gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06560 SH03_RS06565 SH03_06560 SH03_RS06565 1334286 1334669 + Antitermination protein Q homolog from lambdoid prophage DLP12 gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06565 SH03_RS06570 SH03_06565 SH03_RS06570 1334811 1335029 + hypothetical protein gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06570 SH03_RS06575 SH03_06570 SH03_RS06575 1335067 1336047 - transposase gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06575 SH03_RS06580 SH03_06575 SH03_RS06580 1336088 1337155 - porin gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06580 SH03_RS06585 SH03_06580 SH03_RS06585 1337728 1337943 + Lysis protein S homolog from lambdoid prophage DLP12 gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06585 SH03_RS06590 SH03_06585 SH03_RS06590 1337943 1338440 + lysozyme RrrD gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06590 SH03_RS06595 SH03_06590 SH03_RS06595 1338437 1338898 + DLP12 prophage%3B murein endopeptidase gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06595 SH03_RS06600 SH03_06595 SH03_RS06600 1338930 1339223 - Lipoprotein bor homolog from lambdoid prophage DLP12 gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06600 SH03_RS06605 SH03_RS06605 SH03_RS06605 1339374 1339469 - hypothetical protein gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06605 SH03_RS06610 SH03_06600 SH03_RS06610 1339514 1339924 - DLP12 prophage%3B uncharacterized protein gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06610 SH03_RS06615 SH03_06605 SH03_RS06615 1340210 1340416 + DLP12 prophage%3B uncharacterized protein gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06615 SH03_RS06620 SH03_06610 SH03_RS06620 1340581 1340775 - DUF3950 domain-containing protein gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06620 SH03_RS06625 SH03_06615 SH03_RS06625 1340923 1341024 + DNA-packaging protein gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06625 SH03_RS06630 SH03_06620 SH03_RS06630 1341164 1341709 + DNA-packaging protein NU1 homolog gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06630 SH03_RS06635 SH03_06625 SH03_RS06635 1341684 1342427 + tail assembly protein gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06635 SH03_RS06640 SH03_06630 SH03_RS06640 1342482 1342913 - SAM-dependent methyltransferase gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06640 SH03_RS06645 SH03_RS06645 SH03_RS06645 1343205 1343465 + phage tail protein gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06645 SH03_RS06650 SH03_06640 SH03_RS06650 1344011 1344760 + transcriptional regulator gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06650 SH03_RS06655 SH03_06645 SH03_RS06655 1345010 1345963 - protease 7 gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06655 SH03_RS06660 SH03_06650 SH03_RS06660 1346367 1346483 - hypothetical protein gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06660 SH03_RS06665 SH03_06655 SH03_RS06665 1346477 1347238 - porin thermoregulatory protein EnvY involved in the thermoregulation of ompA%2C ompC%2C lamB and envelope proteins gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06665 SH03_RS06670 SH03_06660 SH03_RS06670 1347421 1348311 - PRK09936 family protein gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06670 SH03_RS06675 SH03_06665 SH03_RS06675 1348312 1351284 - bacteriophage N4 adsorption protein A gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06675 SH03_RS06680 SH03_06670 nfrB nfrB 1351271 1353508 - bacteriophage N4 adsorption protein B gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06680 SH03_RS06685 SH03_06675 SH03_RS06685 1353658 1355100 - two-component system sensor histidine kinase gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06685 SH03_RS06690 SH03_06680 SH03_RS06690 1355090 1355773 - two-component system response regulator response regulator in two-component regulatory system with CusS%3B regulates the copper efflux system gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06690 SH03_RS06695 SH03_06685 SH03_RS06695 1355930 1357303 + cation efflux system protein CusC with CusA%2C CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06695 SH03_RS06700 SH03_06690 SH03_RS06700 1357461 1357793 + cation efflux system protein CusF gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06700 SH03_RS06705 SH03_06695 SH03_RS06705 1357809 1359032 + cation efflux system protein CusB with CusA%2C CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06705 SH03_RS06710 SH03_06700 SH03_RS06710 1359044 1362187 + cation efflux system protein CusA gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06710 SH03_RS06715 SH03_06705 SH03_RS06715 1362289 1363665 + phenylalanine-specific permease gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06715 SH03_RS06720 SH03_06710 SH03_RS06720 1363746 1364993 - miniconductance mechanosensitive channel YbdG gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06720 SH03_RS06725 SH03_06715 SH03_RS06725 1365101 1365754 - oxygen-insensitive NAD(P)H nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrofurazone%2C quinones and the anti-tumor agent CB1954%3B NAD(P)H-dependent%3B oxygen insensitive gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06725 SH03_RS06730 SH03_06720 SH03_RS06730 1365848 1366216 - DUF419 domain-containing protein gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06730 SH03_RS06735 SH03_06725 SH03_RS06735 1366281 1366529 - DUF1158 domain-containing protein gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06735 SH03_RS06740 SH03_06730 SH03_RS06740 1366595 1367713 - weak gamma-glutamyl:cysteine ligase gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06740 SH03_RS06745 SH03_06735 SH03_RS06745 1367725 1367874 + hypothetical protein gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06745 SH03_RS06750 SH03_06740 SH03_RS06750 1368166 1368318 + protein HokE gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06750 SH03_RS06755 SH03_06745 SH03_RS06755 1368395 1369507 + transposase gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06755 SH03_RS06760 SH03_06750 SH03_RS06760 1369789 1370418 - 4'-phosphopantetheinyl transferase gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06760 SH03_RS06765 SH03_06755 SH03_RS06765 1370584 1372824 - ferrienterobactin receptor Fep%3B Cbt%3B Cbr%3B FeuB%3B FepA%3B PfeA%3B IroN%3B BfeA%3B outer membrane receptor of ferric enterobactin and colicins B and D%3B interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06765 SH03_RS06770 SH03_06760 SH03_RS06770 1373067 1374269 + enterochelin esterase gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06770 SH03_RS06775 SH03_06765 SH03_RS06775 1374272 1374490 + enterobactin biosynthesis protein YbdZ gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06775 SH03_RS06780 SH03_06770 entF entF 1374487 1378368 + enterobactin synthase component F with EntB%2C EntD%2C and EntE forms the multienzyme complex enterobactin synthase%3B EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06780 SH03_RS06785 SH03_06775 SH03_RS06785 1378584 1379717 + ferric enterobactin transporter FepE in Salmonella is responsible for long O-antigen polymerization%3B may be part of the ferric enterobactin transport system%3B necessary for enetrobactin uptake gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06785 SH03_RS06790 SH03_06780 SH03_RS06790 1379714 1380529 - ferric enterobactin transport ATP-binding protein FepC with FepBDE is involved in the transport of ferric enterobactin gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06790 SH03_RS06795 SH03_06785 SH03_RS06795 1380526 1381518 - ferric anguibactin ABC transporter permease with FepBCD is involved in the transport of ferric enterobactin gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06795 SH03_RS06800 SH03_06790 SH03_RS06800 1381515 1382519 - ferric anguibactin ABC transporter permease with FepBCG is involved in the transport of ferric enterobactin gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06800 SH03_RS06805 SH03_06795 SH03_RS06805 1382630 1383880 + enterobactin exporter EntS protein p43%3B inner membrane protein that exports enterobactin to the periplasmic space%3B member of the major facilitator superfamily (MFS) of transporters gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06805 SH03_RS06810 SH03_06800 SH03_RS06810 1383884 1384840 - ferrienterobactin-binding periplasmic protein with FepCDG is involved in the transport of ferric enterobactin gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06810 SH03_RS06815 SH03_06805 SH03_RS06815 1385215 1386390 + isochorismate synthase EntC gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06815 SH03_RS06820 SH03_06810 entE entE 1386400 1388010 + enterobactin synthase component E bifunctional 2%2C3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase%3B activates the carboxylate group of 2%2C3-dihydroxy-benzoate forming (2%2C3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2%2C3-dihydroxy-benzoate adenylate gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06820 SH03_RS06825 SH03_06815 SH03_RS06825 1388024 1388881 + enterobactin synthase component B 2%2C3 dihydro-2%2C3 dihydroxybenzoate synthase%3B catalyzes the formation of 2%2C3 dihydro-2%2C3 dihydroxybenzoate and pyruvate from isochorismate%3B with Ent DEF is involved in enterobactin synthesis gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06825 SH03_RS06830 SH03_06820 SH03_RS06830 1388881 1389627 + 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase catalyzes the formation of 2%2C3-dihydroxybenzoate from 2%2C3-dihydro-2%2C3-dihydroxybenzoate%3B involved in the biosynthesis of siderophores%2C enterobactin%2C bacillibactin or vibriobactin gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06830 SH03_RS06835 SH03_06825 SH03_RS06835 1389630 1390043 + proofreading thioesterase EntH required for efficient enterobactin production gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06835 SH03_RS06840 SH03_06830 SH03_RS06840 1390224 1392329 + carbon starvation protein A gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06840 SH03_RS06845 SH03_06835 SH03_RS06845 1392512 1392709 + hypothetical protein gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06845 SH03_RS06850 SH03_06840 SH03_RS06850 1392719 1393807 - oxidoreductase member of the iron-containing alcohol dehydrogenase family gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06850 SH03_RS06855 SH03_06845 SH03_RS06855 1393916 1395076 + methionine aminotransferase catalyzes the transfer of an amino moiety%3B preference for methionine followed by histidine and phenylalanine gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06855 SH03_RS06860 SH03_06850 SH03_RS06860 1395077 1395694 - hypothetical protein gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06860 SH03_RS06865 SH03_06855 SH03_RS06865 1395679 1396899 - PAPS reductase-like domain protein gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06865 SH03_RS06870 SH03_06860 SH03_RS06870 1397046 1397948 - transcriptional regulator gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06870 SH03_RS06875 SH03_06865 dsbG dsbG 1398157 1398903 - thiol:disulfide interchange protein DsbG Involved in disulfide bond formation gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06875 SH03_RS06880 SH03_06870 SH03_RS06880 1399275 1399838 + alkyl hydroperoxide reductase subunit C with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols%3B AhpC reduced the hydroperoxide substrate gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06880 SH03_RS06885 SH03_06875 SH03_RS06885 1400083 1401648 + alkyl hydroperoxide reductase subunit F gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06885 SH03_RS06890 SH03_06880 SH03_RS06890 1401769 1402197 - universal stress protein G interacts with GroEL%3B is induced by starvation%2C heat shock and toxic agents gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06890 SH03_RS06895 SH03_06885 SH03_RS06895 1402418 1403656 + Zn-dependent NAD(P)-binding oxidoreductase gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06895 SH03_RS06900 SH03_RS06900 SH03_RS06900 1403660 1403848 - hypothetical protein gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06900 SH03_RS06905 SH03_06895 SH03_RS06905 1403887 1404297 - nucleoside diphosphate kinase regulator Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis%2C CTP for lipid synthesis%2C and GTP for protein elongation gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06905 SH03_RS06910 SH03_06900 SH03_RS06910 1404527 1405333 - ribonuclease I gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06910 SH03_RS06915 SH03_06905 SH03_RS06915 1405447 1406910 - citrate carrier involved in the transport of citrate into the cell along with the export of succinate out of the cell gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06915 SH03_RS06920 SH03_06910 citG citG 1406961 1407839 - 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06920 SH03_RS06925 SH03_06915 citX citX 1407814 1408365 - apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase%3B holo-citrate lyase synthase%3B CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06925 SH03_RS06930 SH03_06920 SH03_RS06930 1408369 1409901 - citrate lyase alpha chain citrate-ACP transferase%2C the alpha subunit catalyzes the formation of (3S)-citryl-CoA from acetyl-CoA and citrate gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06930 SH03_RS06935 SH03_06925 SH03_RS06935 1409912 1410820 - citrate lyase subunit beta citryl-ACP lyase%3B catalyzes the formation of acetate and oxaloacetate from citrate gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06935 SH03_RS06940 SH03_06930 SH03_RS06940 1410817 1411113 - citrate lyase ACP gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06940 SH03_RS06945 SH03_06935 SH03_RS06945 1411128 1412186 - [Citrate [pro-3S]-lyase] ligase activates citrate lyase by acetylation of the gamma subunit gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06945 SH03_RS06950 SH03_06940 dpiB dpiB 1412565 1414223 + sensor histidine kinase regulates the expression of citrate fermentation genes gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06950 SH03_RS06955 SH03_06945 dpiA dpiA 1414192 1414872 + transcriptional regulator regulates the expression of citrate fermentation genes gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06955 SH03_RS06960 SH03_06950 dcuC dcuC 1414913 1416298 - anaerobic C4-dicarboxylate transporter DcuC responsible for the transport of C4-dicarboxylates during anaerobic growth gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06960 SH03_RS06965 SH03_06955 pagP pagP 1416887 1417447 + lipid A palmitoyltransferase PagP catalyzes the transfer of palmitate to lipid A gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06965 SH03_RS06970 SH03_06960 SH03_RS06970 1417622 1417831 + cold-shock protein CspE gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06970 SH03_RS06975 SH03_06965 SH03_RS06975 1417885 1418268 - fluoride efflux channel%2C dual topology membrane protein camphor resistance protein CrcB%3B may be involved in chromosome condensation%3B overexpression in Escherichia coli protects against decondensation by camphor%3B overexpressing the protein results in an increase in supercoiling gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06975 SH03_RS06980 SH03_RS06980 SH03_RS06980 1418361 1419148 + hydrolase gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06980 SH03_RS06985 SH03_06975 tatE tatE 1419277 1419480 + preprotein translocase subunit TatE TatE%3B similar to TatA and found in some proteobacteria%3B part of system that translocates proteins with a conserved twin arginine motif across the inner membrane%3B capable of translocating folded substrates typically those with bound cofactors%3B similar to a protein import system in thylakoid membranes gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06985 SH03_RS06990 SH03_06980 SH03_RS06990 1419581 1420546 - lipoyl synthase catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06990 SH03_RS06995 SH03_06985 SH03_RS06995 1420755 1421708 - LysR family transcriptional regulator gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS06995 SH03_RS07000 SH03_06990 SH03_RS07000 1421766 1421915 + hypothetical protein gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07000 SH03_RS07005 SH03_06995 SH03_RS07005 1421967 1422608 - octanoyltransferase lipoyl/octanoyltransferase%3B catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07005 SH03_RS07010 SH03_07000 SH03_RS07010 1422709 1422972 - hypothetical protein gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07010 SH03_RS07015 SH03_07005 SH03_RS07015 1423082 1424293 - D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 5%3B removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07015 SH03_RS07020 SH03_07010 SH03_RS07020 1424432 1425520 - hypothetical protein septal ring protein%2C suppressor of prc%2C minor lipoprotein gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07020 SH03_RS07025 SH03_07015 SH03_RS07025 1425531 1426643 - rod shape-determining protein RodA gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07025 SH03_RS07030 SH03_07020 SH03_RS07030 1426646 1428547 - penicillin-binding protein 2 gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07030 SH03_RS07035 SH03_07025 SH03_RS07035 1428578 1429045 - ribosomal RNA large subunit methyltransferase H gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07035 SH03_RS07040 SH03_07030 SH03_RS07040 1429049 1429366 - ribosome silencing factor RsfS gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07040 SH03_RS07045 SH03_07035 SH03_RS07045 1429626 1430237 - adenosylcobalamin/alpha-ribazole phosphatase gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07045 SH03_RS07050 SH03_07040 SH03_RS07050 1430261 1430902 - nicotinate-nucleotide adenylyltransferase gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07050 SH03_RS07055 SH03_07045 holA holA 1430904 1431935 - DNA polymerase III subunit delta required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07055 SH03_RS07060 SH03_07050 SH03_RS07060 1431935 1432516 - hypothetical protein rare lipoprotein B%3B involved in the assembly of LPS in the outer membrane gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07060 SH03_RS07065 SH03_07055 leuS leuS 1432531 1435113 - leucine--tRNA ligase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07065 SH03_RS07070 SH03_07060 SH03_RS07070 1435348 1435830 + hypothetical protein gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07070 SH03_RS07075 SH03_07065 SH03_RS07075 1435900 1436877 - hypothetical protein gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07075 SH03_RS07080 SH03_07070 SH03_RS07080 1437041 1437748 + hypothetical protein gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07080 SH03_RS07085 SH03_07075 SH03_RS07085 1437745 1439172 + HscC co-chaperone%2C uncharacterized J domain-containing protein gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07085 SH03_RS07090 SH03_07080 SH03_RS07090 1439182 1439736 - hypothetical protein gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07090 SH03_RS07095 SH03_07085 SH03_RS07095 1439838 1440545 + DUF1266 domain-containing protein gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07095 SH03_RS07100 SH03_07090 SH03_RS07100 1440542 1441993 + J domain-containing HscC co-chaperone%3B Hsc56 gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07100 SH03_RS07105 SH03_07095 SH03_RS07105 1442053 1443723 - chaperone protein HscC gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07105 SH03_RS07110 SH03_07100 rihA rihA 1443807 1444742 - pyrimidine-specific ribonucleoside hydrolase RihA Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil%2C respectively%3B pyrimidine-specific gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07110 SH03_RS07115 SH03_07105 artP artP 1444860 1445585 - glutamate/aspartate transport ATP-binding protein GltL With ArtMQJI transports arginine across the inner membrane gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07115 SH03_RS07120 SH03_07110 SH03_RS07120 1445585 1446259 - glutamate ABC transporter permease with GltJLPS and GadC for glutamate and GltJLP%2C DctA and DcuAB for aspartate is involved in the transport of glutamate and aspartate gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07120 SH03_RS07125 SH03_07115 SH03_RS07125 1446259 1446999 - glutamate ABC transporter permease with GltIKL is involved in the transport of glutamate and aspartate gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07125 SH03_RS07130 SH03_07120 SH03_RS07130 1447169 1448077 - glutamate/aspartate periplasmic-binding protein gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07130 SH03_RS07135 SH03_07125 SH03_RS07135 1448327 1449307 - transposase gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07135 SH03_RS07140 SH03_07130 lnt lnt 1449673 1451211 - apolipoprotein N-acyltransferase Transfers the fatty acyl group on membrane lipoproteins gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07140 SH03_RS07145 SH03_07135 SH03_RS07145 1451236 1452114 - magnesium and cobalt efflux protein CorC involved in the transport of magnesium and cobalt ions gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07145 SH03_RS07150 SH03_07140 SH03_RS07150 1452204 1452671 - endoribonuclease YbeY gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07150 SH03_RS07155 SH03_07145 SH03_RS07155 1452668 1453708 - phoH-like protein gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07155 SH03_RS07160 SH03_07150 SH03_RS07160 1453861 1455285 - tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07160 SH03_RS07165 SH03_07155 ubiF ubiF 1455431 1456606 + 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol hydroxylase catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1%2C4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol%3B functions in the biosynthesis of ubiquinone or coenzyme Q gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07165 SH03_RS07170 SH03_07160 SH03_RS07170 1456760 1456834 - tRNA-Gln tRNA gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07170 SH03_RS07175 SH03_07165 SH03_RS07175 1456872 1456946 - tRNA-Gln tRNA gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07175 SH03_RS07180 SH03_07170 SH03_RS07180 1456994 1457070 - tRNA-Met tRNA gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07180 SH03_RS07185 SH03_07175 SH03_RS07185 1457086 1457160 - tRNA-Gln tRNA gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07185 SH03_RS07190 SH03_07180 SH03_RS07190 1457195 1457269 - tRNA-Gln tRNA gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07190 SH03_RS07195 SH03_07185 SH03_RS07195 1457293 1457377 - tRNA-Leu tRNA gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07195 SH03_RS07200 SH03_07190 SH03_RS07200 1457387 1457463 - tRNA-Met tRNA gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07200 SH03_RS07205 SH03_07195 asnB asnB 1457843 1459507 - asparagine synthetase B [glutamine-hydrolyzing] functions in asparagine biosynthesis%3B converts glutamine%2C aspartate%2C ATP%2C and water to glutamate%2C asparagine%2C pyrophosphate and AMP gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07205 SH03_RS07210 SH03_07200 SH03_RS07210 1459904 1460656 - UMP phosphatase gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07210 SH03_RS07215 SH03_07205 SH03_RS07215 1460704 1461924 - N-acetylglucosamine repressor regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07215 SH03_RS07220 SH03_07210 nagA nagA 1461933 1463081 - N-acetylglucosamine-6-phosphate deacetylase catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07220 SH03_RS07225 SH03_07215 nagB nagB 1463141 1463941 - glucosamine-6-phosphate deaminase catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07225 SH03_RS07230 SH03_07220 SH03_RS07230 1464274 1466220 + PTS N-acetylglucosamine EIICBA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07230 SH03_RS07235 SH03_07225 SH03_RS07235 1466423 1468087 + glutamine--tRNA ligase catalyzes a two-step reaction%2C first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07235 SH03_RS07240 SH03_07230 chiP chiP 1468664 1470070 + chitoporin outer membrane porin involved in the transport of chitooligosaccharides gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07240 SH03_RS07245 SH03_07235 SH03_RS07245 1470120 1470446 + chitosugar-induced verified lipoprotein gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07245 SH03_RS07250 SH03_07240 fur fur 1470530 1470976 - ferric uptake regulation protein negatively regulates a number of operons that encode enzymes involved in iron transport%3B activated by manganese%3B forms a homodimer gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07250 SH03_RS07255 SH03_07245 SH03_RS07255 1470969 1471055 - Fur leader peptide gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07255 SH03_RS07260 SH03_07250 SH03_RS07260 1471021 1471275 + hypothetical protein gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07260 SH03_RS07265 SH03_07255 SH03_RS07265 1471265 1471795 - flavodoxin-1 An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07265 SH03_RS07270 SH03_07260 SH03_RS07270 1471935 1472228 - LexA-regulated protein%2C CopB family gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07270 SH03_RS07275 SH03_07265 SH03_RS07275 1472368 1473132 - esterase gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07275 SH03_RS07280 SH03_07270 SH03_RS07280 1473317 1473862 + negative modulator of initiation of replication negative modulator of the initiation of chromosome replication gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07280 SH03_RS07285 SH03_07275 SH03_RS07285 1473888 1475528 + phosphoglucomutase catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07285 SH03_RS07290 SH03_07280 SH03_RS07290 1475742 1476236 + lipoprotein gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07290 SH03_RS07295 SH03_RS07295 SH03_RS07295 1476277 1476927 - hypothetical protein gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07295 SH03_RS07300 SH03_RS07300 SH03_RS07300 1477051 1477248 - hypothetical protein gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07300 SH03_RS07305 SH03_07295 potE potE 1477276 1478595 - putrescine-ornithine antiporter catalyzes the uptake of putrescine via a proton symport mechanism%2C as well as the efflux of putrescine by a putrescine/ornithine antiport system gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07305 SH03_RS07310 SH03_07300 SH03_RS07310 1478592 1480790 - ornithine decarboxylase gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07310 SH03_RS07315 SH03_07305 SH03_RS07315 1480913 1481170 + hypothetical protein gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07315 SH03_RS07320 SH03_07310 SH03_RS07320 1481386 1482063 - two-component system response regulator response regulator in two-component regulatory system with KdpD%3B regulates the kdp operon involved in potassium transport gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07320 SH03_RS07325 SH03_07315 SH03_RS07325 1482060 1484744 - two-component system sensor histidine kinase KdpD sensory histidine kinase in two-component regulatory system with KdpE%3B signal sensing protein gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07325 SH03_RS07330 SH03_07320 SH03_RS07330 1484737 1485309 - potassium-transporting ATPase C chain One of the components of the high-affinity ATP-driven potassium transport (or KDP)system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07330 SH03_RS07335 SH03_07325 SH03_RS07335 1485318 1487366 - potassium-transporting ATPase B chain One of the components of the high-affinity ATP-driven potassium transport (or KDP) system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07335 SH03_RS07340 SH03_07330 SH03_RS07340 1487389 1489062 - potassium-transporting ATPase A chain catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07340 SH03_RS07345 SH03_07335 kdpF kdpF 1489062 1489151 - protein KdpF one of the components of the high-affinity ATP-driven potassium transport (or KDP) system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07345 SH03_RS07350 SH03_07340 SH03_RS07350 1489464 1489670 + DUF2517 domain-containing protein gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07350 SH03_RS07355 SH03_07345 SH03_RS07355 1489913 1494106 + RHS element protein gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07355 SH03_RS07360 SH03_07350 SH03_RS07360 1494106 1494432 + membrane protein gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07360 SH03_RS07365 SH03_07355 SH03_RS07365 1494550 1495983 + hypothetical protein gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07365 SH03_RS07370 SH03_07360 SH03_RS07370 1495980 1496549 + hypothetical protein gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07370 SH03_RS07375 SH03_07365 SH03_RS07375 1496775 1497029 + transposase gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07375 SH03_RS07380 SH03_07370 SH03_RS07380 1497248 1498291 + hypothetical protein gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07380 SH03_RS07385 SH03_07375 SH03_RS07385 1498422 1499183 + hypothetical protein gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07385 SH03_RS07390 SH03_07380 SH03_RS07390 1499331 1499840 + DUF1722 domain-containing protein gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07390 SH03_RS07395 SH03_07385 SH03_RS07395 1499837 1501255 + deoxyribodipyrimidine photolyase UV-induced DNA repair%3B converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers%3B light dependent gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07395 SH03_RS07400 SH03_07390 SH03_RS07400 1501405 1502886 - dipeptide permease D gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07400 SH03_RS07405 SH03_07395 SH03_RS07405 1503157 1503900 + Nif3-like dinuclear metal center hexameric protein gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07405 SH03_RS07410 SH03_07400 SH03_RS07410 1503923 1504579 + hypothetical protein gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07410 SH03_RS07415 SH03_07405 SH03_RS07415 1504573 1505505 + allophanate hydrolase gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07415 SH03_RS07420 SH03_07410 SH03_RS07420 1505495 1506229 + hypothetical protein gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07420 SH03_RS07425 SH03_07415 SH03_RS07425 1506265 1507056 + endonuclease VII 5-formyluracil/5-hydroxymethyluracil DNA glycosylase%3B involved in base excision repair of DNA damaged by oxidation or by mutagenic agents%3B acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines%3B has apurinic/apyrimidinic lyase activity gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07425 SH03_RS07430 SH03_07420 SH03_RS07430 1507053 1508099 - protein AbrB gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07430 SH03_RS07435 SH03_07425 SH03_RS07435 1508251 1509312 - fimbrial protein gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07435 SH03_RS07440 SH03_07430 SH03_RS07440 1509309 1510037 - periplasmic pilin chaperone gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07440 SH03_RS07445 SH03_07435 SH03_RS07445 1510052 1512499 - outer membrane protein gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07445 SH03_RS07450 SH03_07440 SH03_RS07450 1512559 1513125 - fimbrial-like adhesin protein gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07450 SH03_RS07455 SH03_07445 gltA gltA 1513515 1514798 - citrate synthase type II enzyme%3B in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate%3B allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation%3B forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A%3B functions in TCA cycle%2C glyoxylate cycle and respiration%3B enzyme from Helicobacter pylori is not inhibited by NADH gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07455 SH03_RS07460 SH03_07450 SH03_RS07460 1514786 1514971 + citrate synthase gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07460 SH03_RS07465 SH03_07455 sdhC sdhC 1515492 1515896 + succinate dehydrogenase cytochrome b556 large membrane subunit gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07465 SH03_RS07470 SH03_07460 sdhD sdhD 1515890 1516237 + succinate dehydrogenase hydrophobic membrane anchor subunit gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07470 SH03_RS07475 SH03_07465 sdhA sdhA 1516237 1518003 + succinate dehydrogenase flavoprotein subunit part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07475 SH03_RS07480 SH03_07470 sdhB sdhB 1518019 1518735 + succinate dehydrogenase iron-sulfur subunit part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol%3B the catalytic subunits are similar to fumarate reductase gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07480 SH03_RS07485 SH03_07475 SH03_RS07485 1518794 1519054 + hypothetical protein gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07485 SH03_RS07490 SH03_07480 SH03_RS07490 1519036 1521837 + 2-oxoglutarate dehydrogenase E1 component gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07490 SH03_RS07495 SH03_07485 SH03_RS07495 1521852 1523069 + dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex component of 2-oxoglutarate dehydrogenase complex%3B catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07495 SH03_RS07500 SH03_07490 sucC sucC 1523344 1524510 + succinyl-CoA ligase subunit beta catalyzes the interconversion of succinyl-CoA and succinate gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07500 SH03_RS07505 SH03_07495 SH03_RS07505 1524510 1525379 + succinyl-CoA ligase subunit alpha Catalyzes the only substrate-level phosphorylation in the TCA cycle gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07505 SH03_RS07510 SH03_07500 SH03_RS07510 1525483 1526205 - mannosyl-D-glycerate transport/metabolism system repressor MngR regulates the succiny-lCoA synthetase operon gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07510 SH03_RS07515 SH03_07505 SH03_RS07515 1526374 1528290 + PTS 2-O-a-mannosyl-D-glycerate transporter subunit IIABC involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07515 SH03_RS07520 SH03_07510 SH03_RS07520 1528308 1530941 + mannosylglycerate hydrolase gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07520 SH03_RS07525 SH03_07515 SH03_RS07525 1530966 1531193 + hypothetical protein gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07525 SH03_RS07530 SH03_07520 SH03_RS07530 1531788 1533356 + cytochrome bd-I ubiquinol oxidase subunit 1 part of the aerobic respiratory chain%3B catalyzes the ubiquinol to ubiquinone gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07530 SH03_RS07535 SH03_07525 SH03_RS07535 1533372 1534511 + cytochrome bd-I ubiquinol oxidase subunit 2 gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07535 SH03_RS07540 SH03_07530 SH03_RS07540 1534526 1534639 + cytochrome bd-I ubiquinol oxidase subunit X gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07540 SH03_RS07545 SH03_07535 SH03_RS07545 1534639 1534932 + cyd operon protein YbgE gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07545 SH03_RS07550 SH03_07540 SH03_RS07550 1535082 1535486 + acyl-CoA thioester hydrolase YbgC catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters%3B physiological role remains unknown%3B involved in phospholipid metabolism%3B part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07550 SH03_RS07555 SH03_07545 SH03_RS07555 1535492 1536175 + colicin transporter membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07555 SH03_RS07560 SH03_07550 SH03_RS07560 1536179 1536607 + protein TolR membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07560 SH03_RS07565 SH03_07555 tolA tolA 1536672 1537937 + cell envelope integrity/translocation protein TolA inner membrane component of 7 member Tol-Pal envelope-spanning complex%3B involved in maintaining cell envelope integrity%3B utilized by colicins and filamentous phages for import%3B interacts with TolB%2C Pal%2C and through TolB to various outer membrane porins gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07565 SH03_RS07570 SH03_07560 tolB tolB 1538070 1539362 + protein TolB forms dimers%3B may be involved in cell envelope integrity%3B interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07570 SH03_RS07575 SH03_07565 SH03_RS07575 1539397 1539918 + peptidoglycan-associated lipoprotein gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07575 SH03_RS07580 SH03_07570 SH03_RS07580 1539928 1540719 + periplasmic TolA-binding protein periplasmic protein that interacts with TolA%3B the tol-pal system is probably involved in maintaining cell envelope integrity gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07580 SH03_RS07585 SH03_07575 SH03_RS07585 1540884 1540959 + tRNA-Lys tRNA gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07585 SH03_RS07590 SH03_07580 SH03_RS07590 1541095 1541170 + tRNA-Val tRNA gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07590 SH03_RS07595 SH03_07585 SH03_RS07595 1541173 1541248 + tRNA-Lys tRNA gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07595 SH03_RS07600 SH03_07590 SH03_RS07600 1541398 1541473 + tRNA-Val tRNA gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07600 SH03_RS07605 SH03_07595 SH03_RS07605 1541477 1541552 + tRNA-Lys tRNA gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07605 SH03_RS07610 SH03_07600 SH03_RS07610 1541699 1541774 + tRNA-Lys tRNA gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07610 SH03_RS07615 SH03_07605 SH03_RS07615 1541907 1541982 + tRNA-Lys tRNA gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07615 SH03_RS07620 SH03_07610 SH03_RS07620 1542415 1543458 + quinolinate synthase A 3 different subfamilies%3B catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07620 SH03_RS07625 SH03_07615 SH03_RS07625 1543496 1544215 + nicotinamide riboside transporter PnuC involved in nicotinamide riboside transport gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07625 SH03_RS07630 SH03_07620 SH03_RS07630 1544212 1545153 - zinc transporter ZitB involved in zinc efflux across the cytoplasmic membrane gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07630 SH03_RS07635 SH03_07625 SH03_RS07635 1545267 1545647 - periplasmic protein gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07635 SH03_RS07640 SH03_RS07640 SH03_RS07640 1545742 1545855 - glutamate decarboxylase gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07640 SH03_RS07645 SH03_07635 SH03_RS07645 1545963 1547015 + phospho-2-dehydro-3-deoxyheptonate aldolase Phe-sensitive catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C phenylalanine sensitive gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07645 SH03_RS07650 SH03_07640 gpmA gpmA 1547173 1547925 - 2%2C3-bisphosphoglycerate-dependent phosphoglycerate mutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07650 SH03_RS07655 SH03_07645 galM galM 1548127 1549167 - aldose 1-epimerase mutarotase%3B catalyzes the conversion of beta-galactose to the alpha-anomer%3B links the metabolism of lactose and galactose gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07655 SH03_RS07660 SH03_07650 SH03_RS07660 1549161 1550309 - galactokinase catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07660 SH03_RS07665 SH03_07655 SH03_RS07665 1550313 1551359 - galactose-1-phosphate uridylyltransferase catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07665 SH03_RS07670 SH03_07660 SH03_RS07670 1551369 1552385 - UDP-glucose 4-epimerase gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07670 SH03_RS07675 SH03_07665 SH03_RS07675 1552646 1554118 - molybdate ABC transporter ATPase contains 2 ATP-binding cassettes%3B involved in the transport of molybdenum gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07675 SH03_RS07680 SH03_07675 SH03_RS07680 1554186 1554974 - transcriptional regulator ModE represses the modABCD operon and activates the moaABCD and napFDAGHBC operons gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07680 SH03_RS07685 SH03_07680 SH03_RS07685 1555103 1555252 + multidrug efflux pump accessory protein AcrZ gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07685 SH03_RS07690 SH03_07685 modA modA 1555419 1556192 + molybdate-binding periplasmic protein with ModCB is involved in the high-affinity transport of molybdate gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07690 SH03_RS07695 SH03_07690 modB modB 1556192 1556881 + molybdenum ABC transporter permease part of ModCBA molybdate transporter%3B member of ABC superfamily%3B inner membrane component%3B regulated by repressor protein ModE gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07695 SH03_RS07700 SH03_07695 modC modC 1556884 1557942 + molybdenum import ATP-binding protein ModC Part of the ABC transporter complex modABC involved in molybdenum import gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07700 SH03_RS07705 SH03_07700 SH03_RS07705 1557943 1558761 - pyridoxal phosphate phosphatase YbhA gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07705 SH03_RS07710 SH03_07705 SH03_RS07710 1558916 1559911 + 6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07710 SH03_RS07715 SH03_07710 SH03_RS07715 1559952 1560905 - transcriptional regulator gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07715 SH03_RS07720 SH03_07715 SH03_RS07720 1561089 1562141 + PrpF family isomerase gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07720 SH03_RS07725 SH03_07720 SH03_RS07725 1562217 1563650 + hypothetical protein gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07725 SH03_RS07730 SH03_07725 SH03_RS07730 1563833 1566094 + aconitase gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07730 SH03_RS07735 SH03_07730 SH03_RS07735 1566328 1567611 - acyl-CoA thioesterase gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07735 SH03_RS07740 SH03_07735 SH03_RS07740 1567763 1568239 - kinase inhibitor homolog%2C UPF0098 family YbhB%3B similar to rat and human kinase inhibitory proteins gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07740 SH03_RS07745 SH03_07740 SH03_RS07745 1568298 1569530 - adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7%2C8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07745 SH03_RS07750 SH03_07745 SH03_RS07750 1569674 1570714 + biotin synthase catalyzes the formation of biotin from dethiobiotin gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07750 SH03_RS07755 SH03_07750 SH03_RS07755 1570711 1571865 + 8-amino-7-oxononanoate synthase catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07755 SH03_RS07760 SH03_07755 SH03_RS07760 1571852 1572607 + malonyl-[acyl-carrier protein] O-methyltransferase BioC methyltransferase%3B acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA%2C a biotin precursor%3B member of the bio operon (bioABFCD)%3B in Escherichia coli%2C bioC-null mutants require biotin for growth gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07760 SH03_RS07765 SH03_07760 bioD bioD 1572600 1573277 + ATP-dependent dethiobiotin synthetase BioD 1 DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07765 SH03_RS07770 SH03_07765 SH03_RS07770 1573856 1575877 + UvrABC system protein B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands%2C where it probes for the presence of a lesion gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07770 SH03_RS07775 SH03_07770 SH03_RS07775 1576069 1576977 - hypothetical protein gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07775 SH03_RS07780 SH03_07775 SH03_RS07780 1577220 1577375 - hypothetical protein gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07780 SH03_RS07785 SH03_07780 moaA moaA 1577374 1578363 + cyclic pyranopterin monophosphate synthase together with moaC%2C is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07785 SH03_RS07790 SH03_07785 SH03_RS07790 1578385 1578897 + molybdenum cofactor biosynthesis protein B gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07790 SH03_RS07795 SH03_07790 moaC moaC 1578900 1579385 + cyclic pyranopterin monophosphate synthase accessory protein MoaC%3B along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z%3B involved in molybdenum cofactor biosynthesis gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07795 SH03_RS07800 SH03_07795 moaD moaD 1579378 1579623 + molybdopterin synthase sulfur carrier subunit catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07800 SH03_RS07805 SH03_07800 moaE moaE 1579625 1580077 + molybdopterin synthase catalytic subunit catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07805 SH03_RS07810 SH03_07805 SH03_RS07810 1580214 1580918 + hypothetical protein gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07810 SH03_RS07815 SH03_07810 SH03_RS07815 1581123 1581836 + Bax protein gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07815 SH03_RS07820 SH03_07815 SH03_RS07820 1581872 1582828 - hypothetical protein gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07820 SH03_RS07825 SH03_07820 SH03_RS07825 1582828 1584069 - cardiolipin synthase B gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07825 SH03_RS07830 SH03_07825 SH03_RS07830 1584066 1584827 - hypothetical protein gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07830 SH03_RS07835 SH03_07830 SH03_RS07835 1584960 1585370 + hypothetical protein gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07835 SH03_RS07840 SH03_07835 SH03_RS07840 1585332 1586438 - inner membrane transport permease YbhR gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07840 SH03_RS07845 SH03_07840 SH03_RS07845 1586449 1587582 - inner membrane transport permease YbhS gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07845 SH03_RS07850 SH03_07845 SH03_RS07850 1587575 1589311 - ABC transporter ATPase gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07850 SH03_RS07855 SH03_07850 SH03_RS07855 1589304 1590299 - transporter gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07855 SH03_RS07860 SH03_07855 SH03_RS07860 1590302 1590973 - DUF1956 domain-containing tetR family transcriptional regulator gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07860 SH03_RS07865 SH03_07860 SH03_RS07865 1591202 1592566 + ATP-dependent RNA helicase RhlE this helicase is not essential cell growth gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07865 SH03_RS07870 SH03_07865 SH03_RS07870 1592798 1593247 - swarming motility protein gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07870 SH03_RS07875 SH03_07870 dinG dinG 1593400 1595550 + ATP-dependent helicase DinG helicase involved in DNA repair and perhaps also replication gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07875 SH03_RS07880 SH03_07875 SH03_RS07880 1595578 1596540 + family 3 glycosyltransferase gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07880 SH03_RS07885 SH03_07880 SH03_RS07885 1596681 1597766 + dehydrogenase gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07885 SH03_RS07890 SH03_07885 SH03_RS07890 1597995 1598255 - hypothetical protein gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07890 SH03_RS07895 SH03_07890 SH03_RS07895 1598520 1598786 - RNA polymerase-binding protein DksA gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07895 SH03_RS07900 SH03_07895 SH03_RS07900 1598860 1599537 - PKHD-type hydroxylase gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07900 SH03_RS07905 SH03_07900 SH03_RS07905 1599579 1601861 - catecholate siderophore receptor Fiu Fiu%3B YbiL%3B porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine%2C dihydroxybenzoate) and beta lactam agents%3B Fiu interacts with TonB which provides the energy required for transport across the outer membrane%3B acts as a receptor for iron-siderophores and microcins E492%2C M%2C and H47%3B outer membrane protein gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07905 SH03_RS07910 SH03_07905 SH03_RS07910 1602126 1602386 - colanic acid mucoidy stimulation protein gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07910 SH03_RS07915 SH03_07910 SH03_RS07915 1602662 1603588 + ribosomal RNA large subunit methyltransferase F gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07915 SH03_RS07920 SH03_07915 SH03_RS07920 1603585 1605810 - moderate conductance mechanosensitive channel YbiO gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07920 SH03_RS07925 SH03_07920 glnQ glnQ 1606071 1606793 - glutamine transport ATP-binding protein GlnQ similar to ATP-binding component of ABC transporters gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07925 SH03_RS07930 SH03_07925 glnP glnP 1606790 1607449 - glutamine ABC transporter permease similar to permease component of ABC transporters%3B mutations impair ability of Escherichia coli to transport and utilize glutamine gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07930 SH03_RS07935 SH03_07930 glnH glnH 1607588 1608334 - glutamine-binding periplasmic protein similar to periplasmic-binding component of ABC transporters gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07935 SH03_RS07940 SH03_RS07940 SH03_RS07940 1608380 1608673 - hypothetical protein gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07940 SH03_RS07945 SH03_07940 SH03_RS07945 1608738 1609241 - DNA protection during starvation protein binds DNA in a non-sequence-specific manner and is abundant during stationary phase%3B forms a DNA-protein crystal that protects DNA from damage%3B required for normal starvation response and long-term stationary viability%3B forms a homododecameric complex and sequesters iron which provides protection against oxidative damage gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07945 SH03_RS07950 SH03_07945 SH03_RS07950 1609540 1610427 - threonine/homoserine exporter RhtA gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07950 SH03_RS07955 SH03_07950 ompX ompX 1610780 1611295 + outer membrane protein X OmpX%3B involved in cell adhesion%3B forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface%3B mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07955 SH03_RS07960 SH03_07955 SH03_RS07960 1611344 1612927 - phosphoethanolamine transferase OpgE gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07960 SH03_RS07965 SH03_07960 SH03_RS07965 1613199 1613327 - small protein MntS gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07965 SH03_RS07970 SH03_07965 SH03_RS07970 1613513 1613980 + transcriptional regulator MntR Transcriptional regulator that represses the manganese transporter MntH when manganese is present gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07970 SH03_RS07975 SH03_07970 SH03_RS07975 1613977 1615095 + hypothetical protein gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07975 SH03_RS07980 SH03_07975 SH03_RS07980 1615154 1616074 - transpeptidase gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07980 SH03_RS07985 SH03_07980 SH03_RS07985 1616293 1617885 + ABC transporter ATP-binding protein gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07985 SH03_RS07990 SH03_07985 SH03_RS07990 1618126 1619391 - DUF1479 domain-containing protein gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07990 SH03_RS07995 SH03_07990 SH03_RS07995 1619543 1620358 - sugar phosphatase YbiV gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS07995 SH03_RS08000 SH03_07995 SH03_RS08000 1620504 1622936 - pyruvate formate lyase gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08000 SH03_RS08005 SH03_08000 SH03_RS08005 1622942 1623841 - pyruvate formate lyase activating enzyme gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08005 SH03_RS08010 SH03_08005 SH03_RS08010 1623972 1624634 + fructose-6-phosphate aldolase 1 similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08010 SH03_RS08015 SH03_08010 SH03_RS08015 1624710 1625459 - molybdopterin-synthase adenylyltransferase gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08015 SH03_RS08020 SH03_08015 SH03_RS08020 1625459 1626694 - molybdopterin molybdenumtransferase is involved in the formation of active molybdenum cofactor and the chelation of molybdenum gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08020 SH03_RS08025 SH03_08020 SH03_RS08025 1626898 1627863 + isoaspartyl peptidase gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08025 SH03_RS08030 SH03_08025 SH03_RS08030 1627850 1629721 + glutathione import ATP-binding protein GsiA with GsiBCD is involved in glutathione import%3B GsiA contains 2 ATP-binding domains gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08030 SH03_RS08035 SH03_08030 SH03_RS08035 1629741 1631279 + glutathione-binding protein GsiB with GsiACD is involved in the transport of glutathione into the cell gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08035 SH03_RS08040 SH03_08035 SH03_RS08040 1631297 1632217 + glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08040 SH03_RS08045 SH03_08040 SH03_RS08045 1632220 1633131 + glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08045 SH03_RS08050 SH03_08045 SH03_RS08050 1633309 1635657 + cyclic-di-GMP phosphodiesterase gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08050 SH03_RS08055 SH03_08050 SH03_RS08055 1635665 1636993 + diguanylate cyclase gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08055 SH03_RS08060 SH03_08055 rimO rimO 1637040 1638365 - ribosomal protein S12 methylthiotransferase RimO catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08060 SH03_RS08065 SH03_08060 bssR bssR 1638578 1638961 + biofilm regulator BssR BssS%3B regulator of biofilm through signal secretion%3B disruption of this gene in Escherichia coli led to effects on biofilm formation%2C alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08065 SH03_RS08070 SH03_08065 SH03_RS08070 1639072 1640187 + soluble aldose sugar dehydrogenase YliI gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08070 SH03_RS08075 SH03_08070 SH03_RS08075 1640184 1640810 - glutathione S-transferase gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08075 SH03_RS08080 SH03_08075 SH03_RS08080 1641057 1642259 + D-alanyl-D-alanine carboxypeptidase gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08080 SH03_RS08085 SH03_08080 SH03_RS08085 1642306 1643064 - DeoR family transcriptional regulator gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08085 SH03_RS08090 SH03_08085 SH03_RS08090 1643122 1643718 - undecaprenyl pyrophosphate phosphatase gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08090 SH03_RS08095 SH03_08090 SH03_RS08095 1644003 1645235 + multidrug transporter MdfA gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08095 SH03_RS08100 SH03_08095 SH03_RS08100 1645276 1645554 - hypothetical protein gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08100 SH03_RS08105 SH03_08100 SH03_RS08105 1645646 1646461 - flavin mononucleotide phosphatase YbjI gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08105 SH03_RS08110 SH03_08105 SH03_RS08110 1646461 1647669 - hypothetical protein gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08110 SH03_RS08115 SH03_08110 SH03_RS08115 1647753 1648289 + DNA-binding transcriptional regulator gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08115 SH03_RS08120 SH03_08115 SH03_RS08120 1648464 1650149 - transporter gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08120 SH03_RS08125 SH03_08120 SH03_RS08125 1650419 1650796 + hypothetical protein gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08125 SH03_RS08130 SH03_08125 SH03_RS08130 1650826 1651083 - glutaredoxin functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase%3B also involved in reducing some disulfides in a coupled system with glutathione reductase gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08130 SH03_RS08135 SH03_08130 SH03_RS08135 1651243 1651530 + DUF1418 domain-containing protein YbjC%3B located in the same operon as the nfsA gene%3B member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress%3B induced by paraquat%3B regulated by SoxS%3B unknown function gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08135 SH03_RS08140 SH03_08135 SH03_RS08140 1651514 1652236 + oxygen-insensitive NADPH nitroreductase NADPH-dependent%3B oxygen-insensitive%3B catalyzes the reduction of nitroaromatic compounds gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08140 SH03_RS08145 SH03_08140 SH03_RS08145 1652297 1653199 + ribosomal protein S6--L-glutamate ligase responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08145 SH03_RS08150 SH03_08145 SH03_RS08150 1653287 1653763 + negative regulator of motility%3B multicopy suppressor of coaA(Ts) gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08150 SH03_RS08155 SH03_08150 SH03_RS08155 1653969 1654130 + putrescine/spermidine ABC transporter substrate-binding protein gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08155 SH03_RS08160 SH03_08155 SH03_RS08160 1654114 1655226 + putrescine-binding periplasmic protein gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08160 SH03_RS08165 SH03_08160 potG potG 1655321 1656454 + putrescine transport ATP-binding protein PotG part of the PotFGHI ATP-dependent putrescine transporter gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08165 SH03_RS08170 SH03_08165 SH03_RS08170 1656464 1657417 + spermidine/putrescine ABC transporter permease gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08170 SH03_RS08175 SH03_08170 SH03_RS08175 1657414 1658259 + spermidine/putrescine ABC transporter permease gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08175 SH03_RS08180 SH03_08175 SH03_RS08180 1658319 1658807 + hypothetical protein gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08180 SH03_RS08185 SH03_08180 rumB rumB 1658848 1659975 + 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC RNA uridine methyltransferase B%3B catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08185 SH03_RS08190 SH03_08185 SH03_RS08190 1660174 1660905 - ABC transporter arginine-binding protein 1 with ArtPMQI is involved in arginine transport gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08190 SH03_RS08195 SH03_08190 artM artM 1661196 1661864 - arginine ABC transporter permease ArtM with ArtPQJI acts to transport arginine across the inner membrane gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08195 SH03_RS08200 SH03_08195 SH03_RS08200 1661864 1662580 - arginine ABC transporter permease ArtQ with ArtPMJI transports arginine across the inner membrane gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08200 SH03_RS08205 SH03_08200 SH03_RS08205 1662587 1663318 - arginine ABC transporter substrate-binding protein with ArtPMQI is involved in arginine transport gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08205 SH03_RS08210 SH03_08205 SH03_RS08210 1663336 1664064 - arginine transport ATP-binding protein ArtP gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08210 SH03_RS08215 SH03_08210 SH03_RS08215 1664282 1664797 - lipoprotein induced during stationary phase and by acivicin (a glutamine analog)%3B regulated by Lrp and RpoS gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08215 SH03_RS08220 SH03_08215 SH03_RS08220 1664923 1665246 + hypothetical protein gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08220 SH03_RS08225 SH03_08220 SH03_RS08225 1665243 1666073 + N-acetylmuramoyl-L-alanine amidase catalyzes the cleavage of the bond between muamic acid and l-alanine gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08225 SH03_RS08230 SH03_08225 SH03_RS08230 1666070 1667083 - NAD(P)H-dependent oxidoreductase gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08230 SH03_RS08235 SH03_08230 SH03_RS08235 1667182 1668612 - NAD-dependent oxidoreductase gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08235 SH03_RS08240 SH03_08235 SH03_RS08240 1668623 1669624 - low specificity L-threonine aldolase low- specificity%3B catalyzes the formation of acetaldehyde and glycine from L-threonine%3B acts on L-threonine%2C L-allo-threonine%2C L-threo-phenylserine%2C and L-erythro-phenylserine gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08240 SH03_RS08245 SH03_08240 SH03_RS08245 1669661 1671379 - pyruvate dehydrogenase [ubiquinone] catalyzes the formation of acetate from pyruvate gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08245 SH03_RS08250 SH03_08245 SH03_RS08250 1671512 1672480 - NADH oxidoreductase HCR gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08250 SH03_RS08255 SH03_08250 SH03_RS08255 1672492 1674144 - hydroxylamine reductase gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08255 SH03_RS08260 SH03_08255 SH03_RS08260 1674288 1675187 - transporter gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08260 SH03_RS08265 SH03_08260 SH03_RS08265 1675682 1676377 - aquaporin Z porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08265 SH03_RS08270 SH03_08265 SH03_RS08270 1676590 1676745 - hypothetical protein gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08270 SH03_RS08275 SH03_08270 SH03_RS08275 1676803 1678461 + OLD family ATP-dependent endonuclease%3B DUF2813 family protein gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08275 SH03_RS08280 SH03_08275 SH03_RS08280 1678458 1679450 - DUF535 domain-containing protein gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08280 SH03_RS08285 SH03_08280 SH03_RS08285 1679565 1680680 + MacA family efflux pump subunit confers macrolide resistance via active drug efflux gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08285 SH03_RS08290 SH03_08285 SH03_RS08290 1680677 1682623 + macrolide export ATP-binding/permease MacB with MacA is involved in the export of macrolide gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08290 SH03_RS08295 SH03_08290 SH03_RS08295 1682696 1682920 - cold-shock protein CspD inhibits DNA replication at both initiation and elongation steps%3B stationary phase and starvation inducible gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08295 SH03_RS08300 SH03_08295 clpS clpS 1683243 1683563 + ATP-dependent Clp protease adapter protein ClpS involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation%3B binds to the N-terminal domain of the chaperone ClpA gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08300 SH03_RS08305 SH03_08300 clpA clpA 1683594 1685870 + ATP-dependent Clp protease ATP-binding subunit ClpA ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease%3B directs protease to specific substrates gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08305 SH03_RS08310 SH03_08305 SH03_RS08310 1686214 1686301 - tRNA-Ser tRNA gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08310 SH03_RS08315 SH03_08310 SH03_RS08315 1686555 1686773 - translation initiation factor IF-1 gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08315 SH03_RS08320 SH03_08315 aat aat 1687058 1687762 - leucyl/phenylalanyl-tRNA--protein transferase leucyltransferase%3B phenylalanyltransferse%3B functions in the N-end rule pathway%3B transfers Leu%2C Phe%2C Met%2C from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08320 SH03_RS08325 SH03_08320 SH03_RS08325 1687804 1689525 - ATP-binding/permease CydC in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08325 SH03_RS08330 SH03_08325 SH03_RS08330 1689526 1691292 - ATP-binding/permease CydD in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08330 SH03_RS08335 SH03_08330 SH03_RS08335 1691415 1692380 - thioredoxin reductase catalyzes the transfer of electrons from NADPH to thioredoxin%3B FAD/NAD(P) binding gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08335 SH03_RS08340 SH03_08335 SH03_RS08340 1692925 1693419 + leucine-responsive regulatory protein mediates a global response to leucine%3B acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08340 SH03_RS08345 SH03_08340 SH03_RS08345 1693554 1697543 + cell division protein FtsK DNA-binding membrane protein required for chromosome resolution and partitioning gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08345 SH03_RS08350 SH03_08345 lolA lolA 1697702 1698313 + outer membrane lipoprotein carrier protein LolA participates with LolB in the incorporation of lipoprotein into the outer membrane gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08350 SH03_RS08355 SH03_08350 SH03_RS08355 1698324 1699667 + replication-associated recombination protein A gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08355 SH03_RS08360 SH03_08355 SH03_RS08360 1699758 1701050 + serine--tRNA ligase gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08360 SH03_RS08365 SH03_08360 SH03_RS08365 1701289 1703733 + dimethyl sulfoxide reductase DmsA gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08365 SH03_RS08370 SH03_08365 SH03_RS08370 1703744 1704361 + dimethyl sulfoxide reductase subunit B oxidoreductase%2C Fe-S subunit%3B terminal electron transfer protein for the reduction of DMSO gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08370 SH03_RS08375 SH03_08370 SH03_RS08375 1704363 1705226 + dimethyl sulfoxide reductase subunit C gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08375 SH03_RS08380 SH03_08375 SH03_RS08380 1705261 1705887 - isochorismatase gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08380 SH03_RS08385 SH03_08380 SH03_RS08385 1706201 1707349 + MFS transporter inner membrane protein gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08385 SH03_RS08390 SH03_08385 SH03_RS08390 1707559 1708989 + inner membrane transporter YcaM gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08390 SH03_RS08395 SH03_08390 SH03_RS08395 1708990 1709898 - LysR family transcriptional regulator gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08395 SH03_RS08400 SH03_08395 SH03_RS08400 1709998 1710588 + NAD(P)H-dependent oxidoreductase gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08400 SH03_RS08405 SH03_08400 pflA pflA 1710670 1711410 - pyruvate formate-lyase 1-activating enzyme activates pyruvate formate-lyase 1 under anaerobic conditions gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08405 SH03_RS08410 SH03_08405 SH03_RS08410 1711602 1713884 - formate acetyltransferase 1 formate acetyltransferase%3B catalyzes the formation of formate and acetyl-CoA from pyruvate gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08410 SH03_RS08415 SH03_08410 SH03_RS08415 1713939 1714796 - formate transporter FocA gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08415 SH03_RS08420 SH03_08415 SH03_RS08420 1715202 1716962 - ribosomal protein S12 methylthiotransferase accessory factor YcaO gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08420 SH03_RS08425 SH03_08420 SH03_RS08425 1717092 1717784 + UPF0702 family inner membrane protein gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08425 SH03_RS08430 SH03_08425 SH03_RS08430 1717983 1719071 + phosphoserine aminotransferase catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate%3B catalyzes 4 phosphohydroxy L-threonine from 2-oxo 3 hydroxy 4- phosphobutanoate%3B required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08430 SH03_RS08435 SH03_08430 SH03_RS08435 1719142 1720425 + 3-phosphoshikimate 1-carboxyvinyltransferase gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08435 SH03_RS08440 SH03_08435 SH03_RS08440 1720594 1721358 + molecular chaperone gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08440 SH03_RS08445 SH03_08440 cmk cmk 1721531 1722214 + cytidylate kinase Catalyzes the formation of (d)CDP from ATP and (d)CMP gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08445 SH03_RS08450 SH03_08445 rpsA rpsA 1722325 1723998 + 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08450 SH03_RS08455 SH03_08450 ihfB ihfB 1724158 1724442 + integration host factor subunit beta This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08455 SH03_RS08460 SH03_08455 SH03_RS08460 1724650 1726914 + hypothetical protein gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08460 SH03_RS08465 SH03_08460 SH03_RS08465 1726951 1728699 + lipid A export ATP-binding/permease MsbA involved in the transport of lipid A across the inner membrane gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08465 SH03_RS08470 SH03_08465 lpxK lpxK 1728696 1729682 + tetraacyldisaccharide 4'-kinase transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1%2C4'-bis-phosphate gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08470 SH03_RS08475 SH03_08470 SH03_RS08475 1729719 1730951 + hypothetical protein gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08475 SH03_RS08480 SH03_08475 SH03_RS08480 1731003 1731185 + hypothetical protein gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08480 SH03_RS08485 SH03_08480 SH03_RS08485 1731182 1731928 + 3-deoxy-manno-octulosonate cytidylyltransferase CMP-2-keto-3-deoxyoctulosonic acid synthetase%3B catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08485 SH03_RS08490 SH03_08485 SH03_RS08490 1732082 1732975 + protein kinase-like domain protein gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08490 SH03_RS08495 SH03_08490 SH03_RS08495 1732952 1733731 - envelope biogenesis factor ElyC gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08495 SH03_RS08500 SH03_08495 SH03_RS08500 1733867 1734652 + protein SmtA gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08500 SH03_RS08505 SH03_08500 SH03_RS08505 1734649 1735971 + chromosome partition protein MukF acts with MukB and MukE to condense the chromosome and allow for segregation during cell division gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08505 SH03_RS08510 SH03_08505 SH03_RS08510 1735952 1736656 + chromosome partition protein MukE acts with MukB and MukF to condense the chromosome and allow for segregation during cell division gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08510 SH03_RS08515 SH03_08510 mukB mukB 1736656 1741116 + chromosome partition protein MukB SMC (structural maintenance of chromosomes) family of proteins%3B involved in chromosome condensatin and partitioning%3B forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ%3B mutations result in cell division defects gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08515 SH03_RS08520 SH03_08515 SH03_RS08520 1741377 1743224 + transpeptidase catalyzes the formation of a meso-diaminopimelyl- meso-diaminopimelyl crosslink gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08520 SH03_RS08525 SH03_08520 SH03_RS08525 1743405 1743953 + M15A protease-related family periplasmic protein gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08525 SH03_RS08530 SH03_08525 SH03_RS08530 1743980 1744627 + metal-binding enzyme gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08530 SH03_RS08535 SH03_08530 SH03_RS08535 1744849 1746039 - aspartate aminotransferase gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08535 SH03_RS08540 SH03_08535 SH03_RS08540 1746038 1746208 + hypothetical protein gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08540 SH03_RS08545 SH03_08540 SH03_RS08545 1746224 1747312 - outer membrane protein F gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08545 SH03_RS08550 SH03_08545 SH03_RS08550 1747915 1749315 - asparagine--tRNA ligase gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08550 SH03_RS08555 SH03_08550 SH03_RS08555 1749484 1750686 - nicotinate phosphoribosyltransferase catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08555 SH03_RS08560 SH03_08555 pepN pepN 1750952 1753564 + aminopeptidase N gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08560 SH03_RS08565 SH03_08560 ssuB ssuB 1753607 1754374 - aliphatic sulfonate ABC transporter ATP-binding protein part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic substrate-binding subunit%2C SsuB the ATP-binding subunit and SsuC the permease gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08565 SH03_RS08570 SH03_08565 ssuC ssuC 1754371 1755162 - aliphatic sulfonate ABC transporter permease part of the ABC type transport system for alkanesulfonate SsuABC%3B SsuB the ATP-binding subunit and SsuC the permease gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08570 SH03_RS08575 SH03_08570 SH03_RS08575 1755173 1756318 - alkanesulfonate monooxygenase catalyzes the release of sulfite from alkanesulfonates gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08575 SH03_RS08580 SH03_08575 SH03_RS08580 1756315 1757274 - aliphatic sulfonate ABC transporter substrate-binding protein part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08580 SH03_RS08585 SH03_08580 SH03_RS08585 1757267 1757842 - FMN reductase gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08585 SH03_RS08590 SH03_08585 SH03_RS08590 1758198 1758737 + fimbrial subunit ElfA gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08590 SH03_RS08595 SH03_08590 SH03_RS08595 1758847 1759521 + fimbrial protein gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08595 SH03_RS08600 SH03_08595 SH03_RS08600 1759546 1762146 + usher protein ElfC involved in fimbria production gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08600 SH03_RS08605 SH03_08600 SH03_RS08605 1762137 1763207 + fimbrial-like adhesin protein gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08605 SH03_RS08610 SH03_08605 SH03_RS08610 1763309 1763761 + fimbrial protein gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08610 SH03_RS08615 SH03_08610 SH03_RS08615 1763769 1764284 + fimbrial-like adhesin protein gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08615 SH03_RS08620 SH03_08615 SH03_RS08620 1764277 1764987 + periplasmic pilin chaperone gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08620 SH03_RS08625 SH03_08620 SH03_RS08625 1765098 1766108 + dihydroorotate dehydrogenase catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B uses a flavin nucleotide as an essential cofactor%3B class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus%2C which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08625 SH03_RS08630 SH03_08625 SH03_RS08630 1766282 1766824 + cell division protein ZapC gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08630 SH03_RS08635 SH03_08630 SH03_RS08635 1766821 1767930 - 6-N-hydroxylaminopurine detoxification oxidoreductase gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08635 SH03_RS08640 SH03_08635 rlmL rlmL 1768174 1770282 + ribosomal RNA large subunit methyltransferase K/L catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08640 SH03_RS08645 SH03_08640 SH03_RS08645 1770294 1772201 + ABC transporter ATP-binding protein Uup%3B in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity%3B mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08645 SH03_RS08650 SH03_08645 SH03_RS08650 1772331 1773584 + paraquat-inducible protein A gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08650 SH03_RS08655 SH03_08650 SH03_RS08655 1773589 1775229 + paraquat-inducible protein B gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08655 SH03_RS08660 SH03_08655 SH03_RS08660 1775226 1775789 + DUF330 domain-containing protein gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08660 SH03_RS08665 SH03_08660 SH03_RS08665 1776045 1776212 + ribosome modulation factor gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08665 SH03_RS08670 SH03_08665 SH03_RS08670 1776282 1776800 - 3-hydroxydecanoyl-ACP dehydratase catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2%2C3-decenoyl-ACP or 3%2C4-decenoyl-ACP gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08670 SH03_RS08675 SH03_08670 SH03_RS08675 1776869 1778629 - peptidase gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08675 SH03_RS08680 SH03_08675 SH03_RS08680 1778815 1779267 + macrodomain Ter protein gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08680 SH03_RS08685 SH03_08680 SH03_RS08685 1779343 1780383 - outer membrane protein A OmpA is believed to be a porin%2C involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli%2C and it is known to play a role as a phage receptor%2C a mediator of F-factor dependent conjugation%2C and in maintaining the structural shape of the outer membrane%3B 3a%3B II*%3B G%3B d gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08685 SH03_RS08690 SH03_08685 SH03_RS08690 1780586 1780756 + hypothetical protein gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08690 SH03_RS08695 SH03_08690 SH03_RS08695 1780740 1781249 - cell division inhibitor SulA gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08695 SH03_RS08700 SH03_08695 SH03_RS08700 1781468 1782097 + protein Sxy gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08700 SH03_RS08705 SH03_08700 SH03_RS08705 1782060 1784213 - hypothetical protein gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08705 SH03_RS08710 SH03_08705 SH03_RS08710 1784232 1784678 - hypothetical protein gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08710 SH03_RS08715 SH03_08710 helD helD 1784801 1786855 + helicase IV catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08715 SH03_RS08720 SH03_08715 mgsA mgsA 1786887 1787345 - methylglyoxal synthase catalyzes the formation of methylglyoxal from glycerone phosphate gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08720 SH03_RS08725 SH03_08720 SH03_RS08725 1787441 1788103 - hypothetical protein gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08725 SH03_RS08730 SH03_08725 SH03_RS08730 1788143 1788313 - hypothetical protein gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08730 SH03_RS08735 SH03_08730 SH03_RS08735 1788276 1788689 + CoA-binding protein gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08735 SH03_RS08740 SH03_08735 SH03_RS08740 1788734 1789051 - heat-shock protein HspQ gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08740 SH03_RS08745 SH03_08740 SH03_RS08745 1789109 1790299 - ribosomal RNA large subunit methyltransferase I SAM-dependent%3Bcatalyzes the methylation of cytosine at position 1962 of the 23S rRNA gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08745 SH03_RS08750 SH03_08745 SH03_RS08750 1790394 1790672 + acylphosphatase catalyzes the hydrolysis of acylphosphate gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08750 SH03_RS08755 SH03_08750 SH03_RS08755 1790669 1790998 - sulfurtransferase TusE transfers sulfur from TusBCD complex to MnmA%3B involved in thiouridation of U34 position of some tRNAs gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08755 SH03_RS08760 SH03_08755 SH03_RS08760 1791089 1791748 - Modulator of FtsH protease inner membrane protein binds to the HflBKC complex which modulates FtsH activity gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08760 SH03_RS08765 SH03_08760 SH03_RS08765 1791955 1792042 - tRNA-Ser tRNA gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08765 SH03_RS08770 SH03_08765 SH03_RS08770 1792469 1793587 + hydrogenase-1 small chain gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08770 SH03_RS08775 SH03_08770 SH03_RS08775 1793584 1795377 + hydrogenase-1 large chain gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08775 SH03_RS08780 SH03_08775 SH03_RS08780 1795396 1796103 + Ni/Fe-hydrogenase B-type cytochrome subunit gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08780 SH03_RS08785 SH03_08780 SH03_RS08785 1796100 1796687 + hydrogenase 1 maturation protease HyaD%3B endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08785 SH03_RS08790 SH03_08785 SH03_RS08790 1796684 1797082 + hydrogenase-1 operon protein HyaE involved in processing hydrogenase proteins HyaA and HyaB gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08790 SH03_RS08795 SH03_08790 SH03_RS08795 1797079 1797936 + hydrogenase-1 operon protein HyaF gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08795 SH03_RS08800 SH03_08795 SH03_RS08800 1798070 1799614 + cytochrome bd-II ubiquinol oxidase subunit 1 part of the aerobic respiratory chain%3B catalyzes the ubiquinol to ubiquinone gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08800 SH03_RS08805 SH03_08800 SH03_RS08805 1799626 1800762 + cytochrome bd-II ubiquinol oxidase subunit 2 gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08805 SH03_RS08810 SH03_08805 SH03_RS08810 1800775 1800867 + cytochrome bd-II oxidase subunit gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08810 SH03_RS08815 SH03_08810 SH03_RS08815 1800947 1802245 + periplasmic AppA protein gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08815 SH03_RS08820 SH03_08815 SH03_RS08820 1802360 1804540 - tyrosine-protein kinase etk gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08820 SH03_RS08825 SH03_08820 SH03_RS08825 1804560 1805006 - protein-tyrosine phosphatase Wzb shows phosphatase activity towards the autophosphorylated Wzc protein%2C which induces colanic acid biosynthesis%3B catalyzes the phosphorylation of UDP-glucose dehydrogenase%2C an enzyme involved in colanic acid biosynthesis gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08825 SH03_RS08830 SH03_08825 SH03_RS08830 1804994 1806133 - O-antigen capsule outer membrane auxillary protein export channel required for the translocation of capsular polysaccharide through the outer membrane gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08830 SH03_RS08835 SH03_08830 SH03_RS08835 1806179 1808275 - O-antigen capsule production periplasmic protein gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08835 SH03_RS08840 SH03_08835 SH03_RS08840 1808275 1809021 - O-antigen capsule production periplasmic protein gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08840 SH03_RS08845 SH03_08840 SH03_RS08845 1809018 1809662 - hypothetical protein gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08845 SH03_RS08850 SH03_08845 SH03_RS08850 1809769 1810074 - threonine-rich inner membrane protein GfcA gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08850 SH03_RS08855 SH03_08850 SH03_RS08855 1810196 1810411 - transposase gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08855 SH03_RS08860 SH03_08855 SH03_RS08860 1810357 1810860 + Insertion element IS1 4 protein InsB gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08860 SH03_RS08865 SH03_08860 SH03_RS08865 1811293 1811505 - cold-shock protein CspH gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08865 SH03_RS08870 SH03_08865 SH03_RS08870 1811791 1812003 + cold-shock protein CspG gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08870 SH03_RS08875 SH03_08870 SH03_RS08875 1812177 1812407 + cold-shock protein gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08875 SH03_RS08880 SH03_08875 SH03_RS08880 1812397 1812570 + protein GnsA gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08880 SH03_RS08885 SH03_08880 SH03_RS08885 1812619 1813692 - 4Fe-4S membrane protein gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08885 SH03_RS08890 SH03_08885 SH03_RS08890 1813764 1816478 - sensor histidine kinase Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08890 SH03_RS08895 SH03_08890 SH03_RS08895 1816591 1817619 + periplasmic protein TorT periplasmic sensory protein associated with the TorRS two-component regulatory system gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08895 SH03_RS08900 SH03_08895 SH03_RS08900 1817592 1818284 - two-component system response regulator gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08900 SH03_RS08905 SH03_08900 SH03_RS08905 1818414 1819586 + cytochrome c-type protein TorC with TorA forms the inducible trimethylamine N-oxide reductase which transfers electrons from menaquinones first to TorC then to TorA gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08905 SH03_RS08910 SH03_08905 SH03_RS08910 1819586 1822132 + trimethylamine-N-oxide reductase 1 catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08910 SH03_RS08915 SH03_08910 torD torD 1822129 1822728 + chaperone protein TorD TorD%3B involved in the biogenesis of torA%3B acts on torA before the insertion of the molybdenum cofactor and%2C as a result%2C probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08915 SH03_RS08920 SH03_08915 SH03_RS08920 1822880 1823185 - chaperone modulatory protein CbpM with CpbA modulates the activity of the dnaK chaperone system%3B interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08920 SH03_RS08925 SH03_08920 SH03_RS08925 1823185 1824105 - curved DNA-binding protein functional analog of DnaJ%3B co-chaperone with DnaK%2C molecular chaperone in an adaptive response to environmental stresses other than heat shock gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08925 SH03_RS08930 SH03_08925 SH03_RS08930 1824366 1825622 + hypothetical protein gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08930 SH03_RS08935 SH03_08930 SH03_RS08935 1825915 1827156 + glucose-1-phosphatase gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08935 SH03_RS08940 SH03_08935 SH03_RS08940 1827194 1827421 - hypothetical protein gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08940 SH03_RS08945 SH03_08940 SH03_RS08945 1827442 1828038 - NAD(P)H dehydrogenase (quinone) catalyzes the transfer of electrons from NADH to ubiquinone gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08945 SH03_RS08950 SH03_08945 SH03_RS08950 1828242 1828478 + hypothetical protein gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08950 SH03_RS08955 SH03_08950 SH03_RS08955 1828411 1828584 + KGG family protein gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08955 SH03_RS08960 SH03_08955 SH03_RS08960 1828841 1830169 - transporter gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08960 SH03_RS08965 SH03_08960 SH03_RS08965 1830190 1830684 - FMN reductase gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08965 SH03_RS08970 SH03_08965 SH03_RS08970 1830695 1831285 - malonic semialdehyde reductase RutE gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08970 SH03_RS08975 SH03_08970 SH03_RS08975 1831295 1832095 - reactive intermediate detoxifying aminoacrylate hydrolase gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08975 SH03_RS08980 SH03_08975 SH03_RS08980 1832103 1832489 - aminoacrylate deaminase reactive intermediate detoxification%3B weak enamine/imine deaminase activity gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08980 SH03_RS08985 SH03_08980 SH03_RS08985 1832501 1833193 - peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08985 SH03_RS08990 SH03_08985 SH03_RS08990 1833193 1834284 - pyrimidine monooxygenase RutA gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08990 SH03_RS08995 SH03_08990 SH03_RS08995 1834572 1835210 + transcriptional regulator gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS08995 SH03_RS09000 SH03_08995 putA putA 1835250 1839212 - bifunctional protein PutA proline utilization protein A%3B multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate%3B in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus%3B forms dimers and is a peripherally membrane-associated protein gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09000 SH03_RS09005 SH03_09000 SH03_RS09005 1839267 1839476 + hypothetical protein gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09005 SH03_RS09010 SH03_09005 SH03_RS09010 1839635 1841143 + sodium/proline symporter involved in the sodium dependent uptake of proline gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09010 SH03_RS09015 SH03_09010 SH03_RS09015 1841329 1841650 - hypothetical protein gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09015 SH03_RS09020 SH03_RS09020 SH03_RS09020 1841686 1842515 + iron permease gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09020 SH03_RS09025 SH03_09020 SH03_RS09025 1842573 1843700 + iron uptake system component EfeO with EfeUB forms an iron transport system which is silent in E. coli K-12 due to a mutation in EfeU gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09025 SH03_RS09030 SH03_09025 SH03_RS09030 1843706 1844977 + deferrochelatase/peroxidase EfeB gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09030 SH03_RS09035 SH03_09030 SH03_RS09035 1844895 1845242 - hypothetical protein gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09035 SH03_RS09040 SH03_09035 SH03_RS09040 1845598 1846386 + hypothetical protein gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09040 SH03_RS09045 SH03_09040 pgaD pgaD 1846436 1846849 - poly-beta-1%2C6-N-acetyl-D-glucosamine biosynthesis protein PgaD in Yersinia this gene is involved in biofilm formation and hemin adsorption%3B in Escherichia coli it is involved in PGA biosynthesis and export gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09045 SH03_RS09050 SH03_09045 SH03_RS09050 1846851 1848089 - N-glycosyltransferase predicted polysaccharide polymerase involved in biofilm formation%3B required for the synthesis of the beta-1%2C6-N-acetylglucosamine polysaccharide%3B PgaC%3B in Yersinia the HmsR protein is an inner membrane protein gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09050 SH03_RS09055 SH03_09050 pgaB pgaB 1848169 1850187 - poly-beta-1%2C6-N-acetyl-D-glucosamine N-deacetylase in Yersinia this protein is involved in biofilm formation and hemin adsorption%3B related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1%2C6-N-acetyl-D-glucosamine (PGA) export gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09055 SH03_RS09060 SH03_09055 pgaA pgaA 1850196 1852619 - poly-beta-1%2C6-N-acetyl-D-glucosamine export protein outer membrane protein essential for the synthesis of poly-beta-1%2C6-N-acetyl-D-glucosamine (PGA)%3B adhesin required for biofilm formation%3B PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface%3B member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09060 SH03_RS09065 SH03_09060 SH03_RS09065 1853206 1854564 + diguanylate cyclase gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09065 SH03_RS09070 SH03_09065 SH03_RS09070 1854605 1855471 - transposase gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09070 SH03_RS09075 SH03_09070 SH03_RS09075 1855468 1855767 - transposase gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09075 SH03_RS09080 SH03_09075 SH03_RS09080 1855853 1856176 + hypothetical protein gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09080 SH03_RS09085 SH03_09080 SH03_RS09085 1856173 1857159 + hypothetical protein gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09085 SH03_RS09090 SH03_09085 SH03_RS09090 1857431 1857529 + hypothetical protein gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09090 SH03_RS09095 SH03_09090 SH03_RS09095 1858076 1858163 - tRNA-Ser tRNA gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09095 SH03_RS09100 SH03_09095 ghrA ghrA 1858397 1859335 + glyoxylate/hydroxypyruvate reductase A catalyzes the formation of glycolate and glycerate from glyoxylate and hydroxypyruvate%2C respectively gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09100 SH03_RS09105 SH03_09100 SH03_RS09105 1859390 1860127 + phosphatase gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09105 SH03_RS09110 SH03_09105 SH03_RS09110 1860151 1860705 + chaperone protein YcdY gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09110 SH03_RS09115 SH03_09110 SH03_RS09115 1860807 1861298 + hypothetical protein gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09115 SH03_RS09120 SH03_09115 SH03_RS09120 1861362 1862195 - curli production assembly/transport component CsgG involved in the stability of the curlin proteins during assembly%3B involved in the secretion of the major curlin subunit CsgA across the outer membrane gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09120 SH03_RS09125 SH03_09120 SH03_RS09125 1862222 1862638 - curli production assembly/transport component CsgF nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation)%3B part of the curli secretion and assembly protein complex gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09125 SH03_RS09130 SH03_09125 SH03_RS09130 1862663 1863052 - curli production assembly/transport component CsgE chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation)%3B part of the curli secretion and assembly protein complex gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09130 SH03_RS09135 SH03_09130 SH03_RS09135 1863057 1863707 - CsgBAC operon transcriptional regulatory protein activates the csgBA and csgDEFG operons involved in biofilm formation gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09135 SH03_RS09140 SH03_09135 SH03_RS09140 1864174 1864359 - hypothetical protein gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09140 SH03_RS09145 SH03_09140 csgB csgB 1864462 1864917 + minor curlin subunit CsgB%3B functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09145 SH03_RS09150 SH03_09145 csgA csgA 1864958 1865413 + major curlin subunit the major structural subunit of curlin which assemble to form curli which can bind to fibronectin gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09150 SH03_RS09155 SH03_09150 csgC csgC 1865472 1865804 + curli assembly protein CsgC involved in autoagglutination of curliated cells%3B not involved in production of curli fibers gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09155 SH03_RS09160 SH03_09155 SH03_RS09160 1865925 1866236 + hypothetical protein gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09160 SH03_RS09165 SH03_09160 SH03_RS09165 1866331 1866864 + O-acetyl-ADP-ribose deacetylase interacts and inactivates RNase III during cold shock gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09165 SH03_RS09170 SH03_09165 SH03_RS09170 1866866 1868287 + cardiolipin synthase C gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09170 SH03_RS09175 SH03_09170 opgC opgC 1868295 1869452 - glucan biosynthesis protein C required for the transfer of succinyl residues to osmoregulated periplasmic glucans gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09175 SH03_RS09180 SH03_09175 SH03_RS09180 1869497 1869640 - hypothetical protein gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09180 SH03_RS09185 SH03_09180 SH03_RS09185 1869644 1869775 - hypothetical protein gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09185 SH03_RS09190 SH03_09185 mdoG mdoG 1869828 1871381 + glucan biosynthesis protein G involved in the biosynthesis of osmoregulated periplasmic glucans%3B required for the assembly of the polyglucose structure of glucan gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09190 SH03_RS09195 SH03_09190 SH03_RS09195 1871404 1873917 + glucosyltransferase MdoH necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09195 SH03_RS09200 SH03_09195 SH03_RS09200 1874090 1874317 + outer membrane integrity lipoprotein gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09200 SH03_RS09205 SH03_09200 SH03_RS09205 1874318 1874692 - acidic protein MsyB gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09205 SH03_RS09210 SH03_09205 SH03_RS09210 1874722 1874820 - hypothetical protein gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09210 SH03_RS09215 SH03_09210 SH03_RS09215 1874775 1876001 - multidrug resistance protein MdtG Confers resistance to fosfomycin and deoxycholate gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09215 SH03_RS09220 SH03_09215 SH03_RS09220 1876173 1877093 - lipid A biosynthesis lauroyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09220 SH03_RS09225 SH03_09220 SH03_RS09225 1877318 1878370 + rhodanese-related sulfurtransferase gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09225 SH03_RS09230 SH03_09225 SH03_RS09230 1878412 1878987 - hypothetical protein gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09230 SH03_RS09235 SH03_09230 SH03_RS09235 1878991 1879557 - cytochrome b561 homolog 2 gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09235 SH03_RS09240 SH03_09235 SH03_RS09240 1879818 1879931 - hypothetical protein gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09240 SH03_RS09245 SH03_09240 solA solA 1879979 1881097 - N-methyl-L-tryptophan oxidase catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde%3B FAD-binding%3B can also catalyze the demethylation of other N-methyl amino acids gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09245 SH03_RS09250 SH03_09245 bssS bssS 1881212 1881466 - biofilm regulator BssS BssS%3B regulator of biofilm through signal secretion%3B disruption of this gene in Escherichia coli led to effects on biofilm formation%2C alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09250 SH03_RS09255 SH03_09250 SH03_RS09255 1881753 1881998 - DNA-damage-inducible protein I gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09255 SH03_RS09260 SH03_09255 SH03_RS09260 1882072 1883118 - dihydroorotase gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09260 SH03_RS09265 SH03_09260 SH03_RS09265 1883224 1883784 - lipoprotein gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09265 SH03_RS09270 SH03_09265 SH03_RS09270 1883918 1884565 - glutaredoxin cofactor involved in the reduction of disulfides gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09270 SH03_RS09275 SH03_09270 SH03_RS09275 1884629 1885837 - multidrug resistance protein MdtH Confers resistance to norfloxacin and enoxacin gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09275 SH03_RS09280 SH03_09275 SH03_RS09280 1886073 1886657 + ribosomal-protein-alanine acetyltransferase gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09280 SH03_RS09285 SH03_09280 SH03_RS09285 1886668 1887315 + hypothetical protein gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09285 SH03_RS09290 SH03_09285 SH03_RS09290 1887317 1888240 + oxidoreductase gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09290 SH03_RS09295 SH03_09290 SH03_RS09295 1888350 1889885 + lipid II flippase MurJ gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09295 SH03_RS09300 SH03_09295 SH03_RS09300 1889925 1890341 - flagella synthesis protein FlgN export chaperone for FlgK and FlgL gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09300 SH03_RS09305 SH03_09300 SH03_RS09305 1890346 1890639 - negative regulator of flagellin synthesis regulates the flagellar specific sigma28 transcription factor gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09305 SH03_RS09310 SH03_09305 flgA flgA 1890715 1891374 - flagella basal body P-ring formation protein FlgA required for the assembly of the flagellar basal body P-ring gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09310 SH03_RS09315 SH03_09310 flgB flgB 1891529 1891945 + flagellar biosynthesis protein FlgB with FlgF and C makes up the proximal portion of the flagellar basal body rod%3B Vibrio parahaemolyticus protein is associated with the polar flagella gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09315 SH03_RS09320 SH03_09315 flgC flgC 1891949 1892353 + flagellar basal-body rod protein FlgC with FlgF and B makes up the proximal portion of the flagellar basal body rod gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09320 SH03_RS09325 SH03_09320 flgD flgD 1892365 1893060 + flagellar basal body rod modification protein FlgD acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of some flagellar genes%3B in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09325 SH03_RS09330 SH03_09325 flgE flgE 1893085 1894293 + flagellar hook protein FlgE the hook connects flagellar basal body to the flagellar filament gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09330 SH03_RS09335 SH03_09330 flgF flgF 1894313 1895068 + flagellar basal-body rod protein FlgF FlgF%2C with FlgB and C%2C makes up the proximal portion of the flagellar basal body rod gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09335 SH03_RS09340 SH03_09335 flgG flgG 1895240 1896022 + flagellar basal body rod protein FlgG makes up the distal portion of the flagellar basal body rod gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09340 SH03_RS09345 SH03_09340 flgH flgH 1896075 1896773 + flagellar L-ring protein part of the flagellar basal body which consists of four rings L%2CP%2C S and M mounted on a central rod gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09345 SH03_RS09350 SH03_09345 flgI flgI 1896785 1897882 + flagellar P-ring protein part of the basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod%3B Vibrio parahaemolyticus%2C Yersinia%2C Bradyrhizobium and other bacteria have two copies of this and other flagellar genes%3B the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09350 SH03_RS09355 SH03_09350 flgJ flgJ 1897882 1898823 + peptidoglycan hydrolase FlgJ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09355 SH03_RS09360 SH03_09355 flgK flgK 1898889 1900532 + flagellar hook-associated protein 1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09360 SH03_RS09365 SH03_09360 flgL flgL 1900544 1901497 + flagellar hook-associated protein with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09365 SH03_RS09370 SH03_09365 rne rne 1901693 1904878 - ribonuclease E bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein%3B forms part of the membrane-associated degradosome complex along with PNPase%2C RhlB%2C and enolase gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09370 SH03_RS09375 SH03_09370 SH03_RS09375 1905013 1905333 + hypothetical protein gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09375 SH03_RS09380 SH03_09375 SH03_RS09380 1905451 1906410 + ribosomal large subunit pseudouridine synthase C catalyzes the transformation of uracil to pseudouracil at nucleotides U955%2C U2504%2C and U2580 in 23S rRNA gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09380 SH03_RS09385 SH03_09380 SH03_RS09385 1906522 1907106 - m(7)GTP pyrophosphatase Maf%3B overexpression in Bacillus subtilis inhibits septation in the dividing cell gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09385 SH03_RS09390 SH03_09385 SH03_RS09390 1907305 1907826 + DUF177 domain-containing protein gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09390 SH03_RS09395 SH03_09390 rpmF rpmF 1907878 1908051 + 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09395 SH03_RS09400 SH03_09395 SH03_RS09400 1908162 1909202 + phosphate acyltransferase gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09400 SH03_RS09405 SH03_09400 SH03_RS09405 1909270 1910223 + 3-oxoacyl-ACP synthase III FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09405 SH03_RS09410 SH03_09405 SH03_RS09410 1910239 1911168 + malonyl CoA-ACP transacylase gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09410 SH03_RS09415 SH03_09410 fabG fabG 1911181 1911915 + 3-oxoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09415 SH03_RS09420 SH03_09415 SH03_RS09420 1912126 1912362 + acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09420 SH03_RS09425 SH03_09420 SH03_RS09425 1912450 1913691 + 3-oxoacyl-ACP synthase II FabF%3B beta-ketoacyl-ACP synthase II%2C KASII%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09425 SH03_RS09430 SH03_09425 SH03_RS09430 1913811 1914620 + aminodeoxychorismate lyase catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09430 SH03_RS09435 SH03_09430 SH03_RS09435 1914623 1915645 + septation protein%2C ampicillin sensitivity gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09435 SH03_RS09440 SH03_09435 SH03_RS09440 1915635 1916276 + thymidylate kinase gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09440 SH03_RS09445 SH03_09440 SH03_RS09445 1916273 1917277 + DNA polymerase III subunit delta' catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09445 SH03_RS09450 SH03_09445 SH03_RS09450 1917288 1918085 + DNAse gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09450 SH03_RS09455 SH03_09450 SH03_RS09455 1918380 1919813 + PTS glucose EIICB component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09455 SH03_RS09460 SH03_09455 SH03_RS09460 1919873 1922062 - fhuE receptor gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09460 SH03_RS09465 SH03_09460 SH03_RS09465 1922396 1922755 + HIT-like protein HinT gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09465 SH03_RS09470 SH03_09465 SH03_RS09470 1922758 1923135 + hypothetical protein gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09470 SH03_RS09475 SH03_09470 SH03_RS09475 1923149 1923790 + penicillin-binding protein activator LpoB gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09475 SH03_RS09480 SH03_09475 thiK thiK 1923771 1924595 + thiamine kinase catalyzes the phosphorylation of thiamine to thiamine phosphate gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09480 SH03_RS09485 SH03_09480 SH03_RS09485 1924606 1925631 + beta-hexosaminidase hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09485 SH03_RS09490 SH03_09485 SH03_RS09490 1925654 1926196 + hypothetical protein gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09490 SH03_RS09495 SH03_09490 SH03_RS09495 1926596 1927900 + NADH dehydrogenase gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09495 SH03_RS09500 SH03_09495 SH03_RS09500 1928110 1928649 + hypothetical protein gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09500 SH03_RS09505 SH03_09500 SH03_RS09505 1928711 1929343 - transcriptional regulator gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09505 SH03_RS09510 SH03_09505 SH03_RS09510 1929584 1929841 + multiple stress resistance protein BhsA gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09510 SH03_RS09515 SH03_09510 SH03_RS09515 1929923 1930882 - peptidoglycan-binding protein LysM gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09515 SH03_RS09520 SH03_09515 SH03_RS09520 1931029 1934475 - transcription-repair-coupling factor gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09520 SH03_RS09525 SH03_09520 SH03_RS09525 1934603 1935676 - hypothetical protein gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09525 SH03_RS09530 SH03_09525 SH03_RS09530 1935938 1937137 + lipoprotein-releasing system protein LolC part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09530 SH03_RS09535 SH03_09530 lolD lolD 1937130 1937831 + lipoprotein-releasing system ATP-binding protein LolD outer membrane specific%3B part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09535 SH03_RS09540 SH03_09535 SH03_RS09540 1937831 1939075 + lipoprotein-releasing system protein LolE part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09540 SH03_RS09545 SH03_09540 SH03_RS09545 1939104 1940015 + N-acetyl-D-glucosamine kinase catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09545 SH03_RS09550 SH03_09545 SH03_RS09550 1940031 1940870 + NAD-dependent deacetylase Modulates the activities of several enzymes which are inactive in their acetylated form gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09550 SH03_RS09555 SH03_09550 SH03_RS09555 1940990 1941778 - hypothetical protein gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09555 SH03_RS09560 SH03_09555 SH03_RS09560 1941775 1942236 - hypothetical protein gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09560 SH03_RS09565 SH03_09560 potD potD 1942294 1943340 - spermidine/putrescine-binding periplasmic protein can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotD is a periplasmic component that binds the substrate gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09565 SH03_RS09570 SH03_09565 potC potC 1943337 1944131 - spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotC is a membrane component gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09570 SH03_RS09575 SH03_09570 potB potB 1944128 1944985 - spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotB is a membrane component gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09575 SH03_RS09580 SH03_09575 potA potA 1944969 1946105 - Fe3+/spermidine/putrescine ABC transporter ATP-binding protein functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport%3B PotA is the membrane-associated ATPase gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09580 SH03_RS09585 SH03_09580 SH03_RS09585 1946084 1946299 - hypothetical protein gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09585 SH03_RS09590 SH03_09585 SH03_RS09590 1946355 1947581 + peptidase T gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09590 SH03_RS09595 SH03_09590 SH03_RS09595 1947630 1948751 - 50S ribosomal protein L16 arginine hydroxylase gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09595 SH03_RS09600 SH03_09595 SH03_RS09600 1948827 1950287 - sensor protein PhoQ gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09600 SH03_RS09605 SH03_09600 SH03_RS09605 1950287 1950958 - two-component system response regulator response regulator in two-component regulatory system with PhoQ%3B involved in magnesium starvation and stress gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09605 SH03_RS09610 SH03_09605 SH03_RS09610 1951127 1952497 - adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09610 SH03_RS09615 SH03_09610 SH03_RS09615 1952501 1953142 - lysogenization regulator HflD%3B UPF0274%3B in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein%3B in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09615 SH03_RS09620 SH03_09615 mnmA mnmA 1953178 1954284 - tRNA-specific 2-thiouridylase MnmA catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09620 SH03_RS09625 SH03_09620 SH03_RS09625 1954338 1954799 - phosphatase gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09625 SH03_RS09630 SH03_09625 SH03_RS09630 1954809 1955462 - ribosomal large subunit pseudouridine synthase E catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09630 SH03_RS09635 SH03_09630 SH03_RS09635 1955634 1956884 + isocitrate dehydrogenase Converts isocitrate to alpha ketoglutarate gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09635 SH03_RS09640 SH03_09635 SH03_RS09640 1956987 1957310 - anti-adapter protein IraM interacts RssB preventing the degradation of the stress sigma factor RpoS gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09640 SH03_RS09645 SH03_09640 SH03_RS09645 1957847 1957957 - hypothetical protein gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09645 SH03_RS09650 SH03_09645 SH03_RS09650 1958010 1958414 - DUF1398 domain-containing protein gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09650 SH03_RS09655 SH03_09650 SH03_RS09655 1958635 1959366 - transcriptional regulator gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09655 SH03_RS09660 SH03_09655 SH03_RS09660 1959571 1960782 - blue light- and temperature-regulated antirepressor BluF gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09660 SH03_RS09665 SH03_09660 SH03_RS09665 1961096 1961332 + two-component-system connector protein YcgZ gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09665 SH03_RS09670 SH03_09665 SH03_RS09670 1961375 1961647 + two-component-system connector protein YmgA gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09670 SH03_RS09675 SH03_09670 SH03_RS09675 1961676 1961942 + RcsB connector protein for regulation of biofilm and acid-resistance gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09675 SH03_RS09680 SH03_09675 SH03_RS09680 1962055 1962303 + Blue light%2C low temperature and stress induced protein gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09680 SH03_RS09685 SH03_09680 SH03_RS09685 1962635 1964158 + cyclic-di-GMP phosphodiesterase gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09685 SH03_RS09690 SH03_09685 SH03_RS09690 1964290 1964508 + hypothetical protein gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09690 SH03_RS09695 SH03_09690 SH03_RS09695 1964513 1964641 - hypothetical protein gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09695 SH03_RS09710 SH03_09705 SH03_RS09710 1967612 1967941 - hypothetical protein gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09710 SH03_RS09715 SH03_09710 SH03_RS09715 1967951 1968295 - hypothetical protein gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09715 SH03_RS09720 SH03_09715 SH03_RS09720 1968297 1968470 - hypothetical protein gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09720 SH03_RS09725 SH03_RS09725 SH03_RS09725 1968889 1969214 + ATPase gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09725 SH03_RS09730 SH03_09725 minE minE 1969586 1969852 - cell division topological specificity factor works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09730 SH03_RS09735 SH03_09730 SH03_RS09735 1969856 1970668 - septum site-determining protein MinD ATPase%3B with MinC inhibits cell division by blocking formation of the polar Z ring septums gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09735 SH03_RS09740 SH03_09735 minC minC 1970692 1971387 - septum site-determining protein MinC blocks the formation of polar Z-ring septums gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09740 SH03_RS09745 SH03_09740 SH03_RS09745 1971907 1972275 + hypothetical protein gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09745 SH03_RS09750 SH03_09745 SH03_RS09750 1972378 1972779 - inhibitor of g-type lysozyme gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09750 SH03_RS09755 SH03_09750 SH03_RS09755 1972763 1972978 + hypothetical protein gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09755 SH03_RS09760 SH03_09755 SH03_RS09760 1972988 1973314 + hypothetical protein gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09760 SH03_RS09765 SH03_09760 SH03_RS09765 1973386 1974045 + isomerase/hydrolase gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09765 SH03_RS09770 SH03_09765 SH03_RS09770 1974122 1974583 + hypothetical protein gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09770 SH03_RS09775 SH03_09770 hlyE hlyE 1974790 1975701 - hemolysin E%2C chromosomal Acts by forming a pore-like structure upon contact with mammalian cells gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09775 SH03_RS09780 SH03_09775 SH03_RS09780 1976074 1976493 + protein UmuD binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09780 SH03_RS09785 SH03_09780 SH03_RS09785 1976493 1977761 + protein UmuC binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09785 SH03_RS09790 SH03_09785 SH03_RS09790 1977807 1978337 - disulfide bond formation protein B disulfide oxidoreductase%3B integral membrane protein%3B required for perioplasmic disulfide bond formation%3B oxidizes DsbA protein gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09790 SH03_RS09795 SH03_09790 nhaB nhaB 1978483 1980024 - Na+/H+ antiporter NhaB involved in regulation of intracellular pH under alkaline conditions gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09795 SH03_RS09800 SH03_09795 SH03_RS09800 1980245 1980964 + fatty acid metabolism regulator protein Multifunctional regulator of fatty acid metabolism gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09800 SH03_RS09805 SH03_09800 SH03_RS09805 1981016 1982548 - SpoVR family stationary phase gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09805 SH03_RS09810 SH03_09805 SH03_RS09810 1982878 1984176 + D-amino acid dehydrogenase catalyzes the oxidative deamination of D-amino acids gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09810 SH03_RS09815 SH03_09810 SH03_RS09815 1984186 1985256 + alanine racemase catabolic converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09815 SH03_RS09820 SH03_09815 cvrA cvrA 1985642 1987378 - K+/H+ antiporter NhaP2 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter%3B can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09820 SH03_RS09825 SH03_09820 ldcA ldcA 1987473 1988387 - murein tetrapeptide carboxypeptidase catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09825 SH03_RS09830 SH03_09825 emtA emtA 1988487 1989098 + murein transglycosylase catalyzes the cleavage of 1-4 beta-glycoside linkaged between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09830 SH03_RS09835 SH03_09830 SH03_RS09835 1989100 1989834 - flagellar brake protein YcgR gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09835 SH03_RS09840 SH03_09835 SH03_RS09840 1990035 1990289 + hypothetical protein gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09840 SH03_RS09845 SH03_09840 SH03_RS09845 1990467 1990907 + hypothetical protein gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09845 SH03_RS09850 SH03_09845 treA treA 1990986 1992683 - periplasmic trehalase periplasmic%3B catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09850 SH03_RS09855 SH03_09850 SH03_RS09855 1993003 1994421 - dihydroxyacetone kinase subunit DhaM phosphotransferaese subunit%3B phosphorylates dihydroxyacetone along with DhaK/DhaL gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09855 SH03_RS09860 SH03_09855 SH03_RS09860 1994432 1995064 - dihydroxyacetone kinase subunit DhaL with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09860 SH03_RS09865 SH03_09860 SH03_RS09865 1995075 1996145 - dihydroxyacetone kinase subunit DhaK with DhaL and DhaM forms dihydroxyacetone kinase%2C which is responsible for phosphorylating dihydroxyacetone%3B DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09865 SH03_RS09870 SH03_09865 SH03_RS09870 1996373 1998292 + dihydroxyacetone kinase subunit DhaR Positively regulates the dhaKLM operon from a sigma-70 promoter gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09870 SH03_RS09875 SH03_09870 SH03_RS09875 1998392 2001259 - adhesin gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09875 SH03_RS09880 SH03_09875 SH03_RS09880 2001604 2001783 + hypothetical protein gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09880 SH03_RS09885 SH03_09880 ychF ychF 2002028 2003119 - ribosome-binding ATPase YchF EngD%3B translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09885 SH03_RS09890 SH03_09885 SH03_RS09890 2003236 2003820 - peptidyl-tRNA hydrolase gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09890 SH03_RS09895 SH03_09890 SH03_RS09895 2004098 2004376 + membrane protein YchH%3B transcription activated by CRP (cyclic AMP receptor protein)%2C a global transcription factor involved in regulation of metabolism in enteric bacteria%3B ychH presents a class II promoter to bind CRP%3B unknown function gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09895 SH03_RS09900 SH03_09895 SH03_RS09900 2004431 2006083 - transporter role in sulfate transport across the inner membrane%3B member of the SulP family of sulfate transporters%3B seems to mediate transport via sulfate/proton symport gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09900 SH03_RS09905 SH03_09900 SH03_RS09905 2006235 2007182 - ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09905 SH03_RS09910 SH03_09905 SH03_RS09910 2007333 2008184 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09910 SH03_RS09915 SH03_09910 lolB lolB 2008184 2008807 - outer membrane lipoprotein LolB Incorporates lipoproteins in the outer membrane after they are released by the LolA protein gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09915 SH03_RS09920 SH03_09915 hemA hemA 2009021 2010277 + glutamyl-tRNA reductase catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH%3B the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid%3B functions in porphyrin (tetrapyrroles) biosynthesis%3B the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09920 SH03_RS09925 SH03_09920 prfA prfA 2010319 2011401 + peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09925 SH03_RS09930 SH03_09925 SH03_RS09930 2011401 2012234 + release factor glutamine methyltransferase HemK%3B PrmC%3B transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09930 SH03_RS09935 SH03_09930 SH03_RS09935 2012231 2012623 + protein sirB2 gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09935 SH03_RS09940 SH03_09935 SH03_RS09940 2012627 2013436 + protein sirB1 gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09940 SH03_RS09945 SH03_09940 SH03_RS09945 2013472 2014326 + 2-dehydro-3-deoxyphosphooctonate aldolase catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09945 SH03_RS09950 SH03_09945 SH03_RS09950 2014475 2014609 - hypothetical protein gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09950 SH03_RS09955 SH03_09950 SH03_RS09955 2015010 2015144 - hypothetical protein gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09955 SH03_RS09960 SH03_09955 SH03_RS09960 2015521 2016621 - sodium/proton antiporter ChaA gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09960 SH03_RS09965 SH03_09960 chaB chaB 2016891 2017121 + cation transport regulator ChaB in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA%3B has weak affinity for calcium and magnesium ions gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09965 SH03_RS09970 SH03_09965 SH03_RS09970 2017279 2017974 + glutathione-specific gamma-glutamylcyclotransferase gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09970 SH03_RS09975 SH03_09970 SH03_RS09975 2018018 2018371 - hypothetical protein gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09975 SH03_RS09980 SH03_09975 SH03_RS09980 2018556 2019950 + invasin gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09980 SH03_RS09985 SH03_09980 SH03_RS09985 2019951 2020601 - transcriptional regulator two-component response regulator NarL%3B phosphorylated by NarQ%3B activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09985 SH03_RS09990 SH03_09985 SH03_RS09990 2020594 2022390 - nitrate/nitrite two-component system sensor histidine kinase gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09990 SH03_RS09995 SH03_09990 SH03_RS09995 2022416 2022634 + hypothetical protein gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS09995 SH03_RS10000 SH03_09995 SH03_RS10000 2022729 2024120 + nitrate/nitrite transporter NarK involved in the transport of nitrate and nitrite gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10000 SH03_RS10005 SH03_10000 narZ narZ 2024636 2028379 + respiratory nitrate reductase 1 alpha chain with NarYV catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli%3B expression of nitrate reductase Z is not dependent on nitrate levels gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10005 SH03_RS10010 SH03_10005 narH narH 2028376 2029914 + nitrate reductase subunit beta with NarGJI catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10010 SH03_RS10015 SH03_10010 SH03_RS10015 2029911 2030621 + nitrate reductase molybdenum cofactor assembly chaperone NarJ delta subunit of nitrate reductase 1%3B chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1 gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10015 SH03_RS10020 SH03_10015 narI narI 2030621 2031298 + respiratory nitrate reductase subunit gamma with NarGJH catalyzes the reduction of nitrate%3B the gamma subunit localizes NarGHI to the membrane%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10020 SH03_RS10025 SH03_10020 SH03_RS10025 2031481 2031756 + hypothetical protein gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10025 SH03_RS10030 SH03_10025 SH03_RS10030 2032016 2032100 - tRNA-Tyr tRNA gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10030 SH03_RS10035 SH03_10030 SH03_RS10035 2032310 2032394 - tRNA-Tyr tRNA gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10035 SH03_RS10040 SH03_10035 SH03_RS10040 2032554 2033396 - formyltetrahydrofolate deformylase gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10040 SH03_RS10045 SH03_10040 SH03_RS10045 2033446 2033904 - hypothetical protein gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10045 SH03_RS10050 SH03_10045 SH03_RS10050 2034017 2034922 + NTE family protein RssA gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10050 SH03_RS10055 SH03_10050 SH03_RS10055 2035014 2036027 + regulator of RpoS gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10055 SH03_RS10060 SH03_10055 SH03_RS10060 2036229 2037137 + UTP--glucose-1-phosphate uridylyltransferase together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase%2C an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate%3B regulates cellular levels of UDP-glucose gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10060 SH03_RS10065 SH03_10060 SH03_RS10065 2037281 2037694 - DNA-binding protein H-NS gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10065 SH03_RS10070 SH03_10065 SH03_RS10070 2038299 2038916 + thymidine kinase catalyzes the formation of thymidine 5'-phosphate from thymidine gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10070 SH03_RS10075 SH03_10070 SH03_RS10075 2039198 2039788 - transposase gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10075 SH03_RS10080 SH03_RS10080 SH03_RS10080 2039733 2040049 - hypothetical protein gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10080 SH03_RS10085 SH03_10080 SH03_RS10085 2040218 2042893 - aldehyde-alcohol dehydrogenase gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10085 SH03_RS10090 SH03_10085 SH03_RS10090 2043370 2044017 + hypothetical protein gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10090 SH03_RS10095 SH03_10090 SH03_RS10095 2044755 2046386 + peptide ABC transporter substrate-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10095 SH03_RS10100 SH03_10095 oppB oppB 2046472 2047392 + peptide ABC transporter permease gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10100 SH03_RS10105 SH03_10100 SH03_RS10105 2047407 2048315 + peptide ABC transporter permease with OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10105 SH03_RS10110 SH03_10105 oppD oppD 2048327 2049340 + oligopeptide transport ATP-binding protein OppD gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10110 SH03_RS10115 SH03_10110 SH03_RS10115 2049337 2050341 + oligopeptide transport ATP-binding protein OppF with OppABCD is involved in the transport of oligopeptides%3B OppF and OppD are ATP-binding proteins gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10115 SH03_RS10120 SH03_10115 SH03_RS10120 2050394 2050723 - hypothetical protein highly acidic protein%3B the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi)%3B binds heat-unstable protein (HU-alpha) which is a histone-like protein gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10120 SH03_RS10125 SH03_10120 cls cls 2050758 2052218 - cardiolipin synthase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10125 SH03_RS10130 SH03_10125 SH03_RS10130 2052250 2052534 + hypothetical protein gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10130 SH03_RS10135 SH03_10130 SH03_RS10135 2052589 2053842 - voltage-gated potassium channel Kch gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10135 SH03_RS10140 SH03_10135 SH03_RS10140 2054142 2054438 - hypothetical protein unknown function%3B YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase%2C but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10140 SH03_RS10145 SH03_10140 SH03_RS10145 2054662 2055381 + protein TonB membrane spanning protein in TonB-ExbB-ExbD complex%3B transduces proton motive force of the cytoplasmic membrane to outer membrane transporters%3B involved in the transport of ron-siderophore complexes%2C vitamin B12 and colicins gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10145 SH03_RS10150 SH03_10145 SH03_RS10150 2055421 2055819 - acyl-CoA thioester hydrolase YciA gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10150 SH03_RS10155 SH03_10150 SH03_RS10155 2055924 2056463 - intracellular septation protein A Involved in cell division%3B probably involved in intracellular septation gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10155 SH03_RS10160 SH03_10155 SH03_RS10160 2056493 2057236 - hypothetical protein gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10160 SH03_RS10165 SH03_10160 SH03_RS10165 2057593 2058231 + outer membrane protein W receptor for colicin S4 gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10165 SH03_RS10170 SH03_10165 SH03_RS10170 2058291 2058797 - hypothetical protein gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10170 SH03_RS10175 SH03_10170 SH03_RS10175 2058843 2059343 - hypothetical protein gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10175 SH03_RS10180 SH03_10175 SH03_RS10180 2059429 2059608 - hypothetical protein gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10180 SH03_RS10185 SH03_10180 SH03_RS10185 2059989 2060795 - tryptophan synthase subunit alpha gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10185 SH03_RS10190 SH03_10185 SH03_RS10190 2060795 2061988 - tryptophan synthase subunit beta catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10190 SH03_RS10195 SH03_10190 SH03_RS10195 2062000 2063358 - phosphoribosylanthranilate isomerase monomeric bifunctional protein%3B functions in tryptophan biosynthesis pathway%3B phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10195 SH03_RS10200 SH03_10195 SH03_RS10200 2063362 2064957 - bifunctional protein TrpGD bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase%3B TrpD%3B forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine%3B also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate%3B functions in tryptophan biosynthesis gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10200 SH03_RS10205 SH03_10200 SH03_RS10205 2064957 2066519 - anthranilate synthase component 1 gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10205 SH03_RS10210 SH03_10205 SH03_RS10210 2066793 2067674 + PHP domain-containing protein YciV gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10210 SH03_RS10215 SH03_10210 SH03_RS10215 2067671 2068291 + RNA binding protein gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10215 SH03_RS10220 SH03_10215 SH03_RS10220 2068319 2070214 + hypothetical protein gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10220 SH03_RS10225 SH03_10220 SH03_RS10225 2070425 2071300 + ribosomal large subunit pseudouridine synthase B catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10225 SH03_RS10230 SH03_10225 SH03_RS10230 2071340 2071930 - cob(I)yrinic acid a%2Cc-diamide adenosyltransferase catalyzes the formation of adenosylcobalamide from cobinamide and the formation of coenzyme B12 from cob(I)alamin gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10230 SH03_RS10235 SH03_10230 SH03_RS10235 2071927 2072685 - oxoacyl-ACP reductase gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10235 SH03_RS10240 SH03_10235 SH03_RS10240 2072729 2072893 - hypothetical protein gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10240 SH03_RS10245 SH03_10240 SH03_RS10245 2072905 2073954 + protease multicopy suppressor of htrA(degP) gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10245 SH03_RS10250 SH03_10245 SH03_RS10250 2073990 2074241 - hypothetical protein gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10250 SH03_RS10255 SH03_10250 SH03_RS10255 2074346 2074498 + hypothetical protein gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10255 SH03_RS10260 SH03_10255 SH03_RS10260 2074621 2077218 + DNA topoisomerase 1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10260 SH03_RS10265 SH03_10260 cysB cysB 2077428 2078402 + transcriptional regulator LysR-type transcriptional regulator%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon%3B autoregulates expression%3B crystal structure of Klebsiella aerogenes showed tetramer formation gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10265 SH03_RS10270 SH03_10265 SH03_RS10270 2078733 2078861 + hypothetical protein gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10270 SH03_RS10275 SH03_10270 SH03_RS10275 2078864 2079031 + hypothetical protein gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10275 SH03_RS10280 SH03_10275 SH03_RS10280 2079105 2079230 - hypothetical protein gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10280 SH03_RS10285 SH03_10285 SH03_RS10285 2079404 2082079 + aconitate hydratase Catalyzes the conversion of citrate to isocitrate gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10285 SH03_RS10290 SH03_10290 ribA ribA 2082143 2082733 - GTP cyclohydrolase-2 catalyzes the conversion of GTP to formate and 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10290 SH03_RS10295 SH03_10295 SH03_RS10295 2082903 2083667 + phosphatidylglycerophosphatase B gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10295 SH03_RS10300 SH03_10300 SH03_RS10300 2083816 2084124 + LPS assembly protein A gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10300 SH03_RS10305 SH03_10305 SH03_RS10305 2084131 2085300 + LPS assembly protein B gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10305 SH03_RS10310 SH03_10310 SH03_RS10310 2085494 2086231 + orotidine 5'-phosphate decarboxylase gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10310 SH03_RS10315 SH03_10315 SH03_RS10315 2086231 2086557 + initiation factor function involved in start site selection during the initiation of translation gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10315 SH03_RS10320 SH03_10320 SH03_RS10320 2086683 2086901 - osmotically-inducible lipoprotein B gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10320 SH03_RS10325 SH03_10325 SH03_RS10325 2087170 2087919 - DeoR family transcriptional regulator gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10325 SH03_RS10330 SH03_10330 SH03_RS10330 2088009 2088182 - hypothetical protein gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10330 SH03_RS10335 SH03_10335 SH03_RS10335 2088330 2090315 - cyclic di-GMP phosphodiesterase Gmr c-di-GMP phosphodiesterase%3B probably degrades signalling molecule c-di-GMP gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10335 SH03_RS10340 SH03_10340 SH03_RS10340 2090369 2090473 + hypothetical protein gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10340 SH03_RS10345 SH03_10345 SH03_RS10345 2090551 2092485 - exoribonuclease 2 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10345 SH03_RS10350 SH03_10350 SH03_RS10350 2092553 2093680 - oxidoreductase gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10350 SH03_RS10355 SH03_10355 SH03_RS10355 2093824 2094612 - enoyl-ACP reductase [NADH] Catalyzes a key regulatory step in fatty acid biosynthesis gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10355 SH03_RS10360 SH03_10365 SH03_RS10360 2094980 2095330 - hypothetical protein gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10360 SH03_RS10365 SH03_10370 SH03_RS10365 2095401 2096207 - peptide transport system ATP-binding protein SapF gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10365 SH03_RS10370 SH03_10375 SH03_RS10370 2096209 2097201 - peptide transport system ATP-binding protein SapD involved in resistance to antimibial peptides gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10370 SH03_RS10375 SH03_10380 SH03_RS10375 2097201 2098091 - peptide ABC transporter permease gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10375 SH03_RS10380 SH03_10385 SH03_RS10380 2098078 2099043 - peptide ABC transporter permease gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10380 SH03_RS10385 SH03_10390 SH03_RS10385 2099040 2100683 - peptide transport periplasmic protein SapA gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10385 SH03_RS10390 SH03_10395 SH03_RS10390 2100726 2100926 - hypothetical protein gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10390 SH03_RS10395 SH03_10400 SH03_RS10395 2100996 2101241 - DUF2543 domain-containing protein gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10395 SH03_RS10400 SH03_10405 SH03_RS10400 2101375 2102760 - putrescine importer gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10400 SH03_RS10405 SH03_10410 SH03_RS10405 2103063 2104481 - gamma-glutamylputrescine synthetase PuuA gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10405 SH03_RS10410 SH03_10415 puuD puuD 2104693 2105457 + gamma-glutamyl-gamma-aminobutyrate hydrolase catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10410 SH03_RS10415 SH03_10420 SH03_RS10415 2105484 2106041 + transcriptional regulator regulates genes involved in putrescine degradation gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10415 SH03_RS10420 SH03_10425 SH03_RS10420 2106316 2107803 + aldehyde dehydrogenase PuuC gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10420 SH03_RS10425 SH03_10430 SH03_RS10425 2107805 2109085 + gamma-glutamylputrescine oxidoreductase catalyzes the formation of gamma-glutamyl-gamma-aminobutyraldehyde from gamma-glutamylputrescine gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10425 SH03_RS10430 SH03_10435 SH03_RS10430 2109123 2110388 + 4-aminobutyrate aminotransferase PuuE catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10430 SH03_RS10435 SH03_10440 pspF pspF 2110508 2111485 - psp operon transcriptional activator transcriptional activator for pspABCE which are induced in response to phage proteins%2C membrane altering stresses%2C and impaired proton expor gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10435 SH03_RS10440 SH03_10445 SH03_RS10440 2111652 2112320 + phage shock protein A involved in maintaining membrane potential under membrane stress conditions%3B also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10440 SH03_RS10445 SH03_10450 pspB pspB 2112374 2112598 + phage shock protein DNA-binding transcriptional regulator%3B acts together with PspC to induce psp operon during infection with phage%2C exposure to ethanol or osmotic shock%3B forms a complex with PspA and C%3B PspC is required for PspAB binding gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10445 SH03_RS10450 SH03_10455 SH03_RS10450 2112598 2112957 + phage shock protein C with PsbB forms toxin/antitoxin pair%3B activates the psp operon in response to phage infection%2C exposure to ethanol or osmotic shock gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10450 SH03_RS10455 SH03_10460 SH03_RS10455 2112966 2113187 + phage shock protein D gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10455 SH03_RS10460 SH03_10465 SH03_RS10460 2113262 2113576 + thiosulfate sulfurtransferase PspE rhodanese%3B catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10460 SH03_RS10465 SH03_10470 SH03_RS10465 2113789 2115468 + alpha amylase catalytic domain family protein gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10465 SH03_RS10470 SH03_10475 SH03_RS10470 2115482 2116774 + sugar ABC transporter substrate-binding protein gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10470 SH03_RS10475 SH03_10480 SH03_RS10475 2116795 2117676 + ABC transporter permease gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10475 SH03_RS10480 SH03_10485 SH03_RS10480 2117663 2118505 + ABC transporter permease gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10480 SH03_RS10485 SH03_10490 SH03_RS10485 2118536 2119588 + Zn-dependent NAD(P)-binding oxidoreductase gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10485 SH03_RS10490 SH03_10495 SH03_RS10490 2119607 2120395 + hypothetical protein gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10490 SH03_RS10495 SH03_10500 SH03_RS10495 2120405 2121460 + NADH-binding oxidoreductase gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10495 SH03_RS10500 SH03_10505 SH03_RS10500 2121457 2123724 + family 65 glycosyl hydrolase gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10500 SH03_RS10505 SH03_10510 SH03_RS10505 2123721 2124380 + beta-phosphoglucomutase catalyzes the interconversion of beta-D-glucose 6-phosphate to beta-D-glucose 1-phosphate gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10505 SH03_RS10510 SH03_RS10510 SH03_RS10510 2124394 2125475 + sugar ABC transporter ATP-binding protein gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10510 SH03_RS10515 SH03_10520 SH03_RS10515 2125520 2126425 + outer membrane protein G gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10515 SH03_RS10520 SH03_10525 SH03_RS10520 2126536 2127534 - LacI family transcriptional regulator gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10520 SH03_RS10525 SH03_10530 SH03_RS10525 2127690 2129087 + DUF463 domain-containing protein gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10525 SH03_RS10530 SH03_10535 SH03_RS10530 2129084 2130145 + hypothetical protein gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10530 SH03_RS10535 SH03_10540 SH03_RS10535 2130293 2131834 + transcriptional regulator regulates genes involved in the biosynthesis and transport of aromatic amino acids gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10535 SH03_RS10540 SH03_10545 tpx tpx 2131878 2132384 - thiol peroxidase antioxidant activity%3B thioredoxin-dependent thiol peroxidase%3B forms homodimers in solution%3B shows substrate specificity to alkyl hydroperoxides%3B periplasmic protein gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10540 SH03_RS10545 SH03_10550 SH03_RS10545 2132503 2133468 + L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-alanyl-D-glutamate to L-alanyl-L-glutamate gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10545 SH03_RS10550 SH03_10555 SH03_RS10550 2133443 2134171 - protein MpaA gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10550 SH03_RS10555 SH03_10560 SH03_RS10555 2134253 2134435 - hypothetical protein gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10555 SH03_RS10560 SH03_10565 SH03_RS10560 2134506 2135426 - S9 homolog non-peptidase gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10560 SH03_RS10565 SH03_10570 SH03_RS10565 2135564 2136463 + transcriptional regulator gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10565 SH03_RS10570 SH03_10575 SH03_RS10570 2136552 2136677 + hypothetical protein gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10570 SH03_RS10575 SH03_10580 SH03_RS10575 2136800 2138413 + periplasmic murein peptide-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10575 SH03_RS10580 SH03_10585 SH03_RS10580 2138464 2139495 - low conductance mechanosensitive channel YnaI gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10580 SH03_RS10585 SH03_10590 SH03_RS10585 2139685 2140665 + transposase gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10585 SH03_RS10590 SH03_10595 SH03_RS10590 2140938 2141195 + DUF2534 domain-containing protein gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10590 SH03_RS10595 SH03_10600 SH03_RS10595 2141245 2142195 - universal stress protein E with UspC and UspD is involved in resistance to UV irradiation gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10595 SH03_RS10600 SH03_10605 SH03_RS10600 2142347 2143099 - fumarate and nitrate reduction regulatory protein Global transcription factor that controls the expression of over 100 target genes in response to anoxia gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10600 SH03_RS10605 SH03_10610 SH03_RS10605 2143294 2143809 - methylated-DNA--protein-cysteine methyltransferase gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10605 SH03_RS10610 SH03_10615 SH03_RS10610 2143820 2145346 - p-aminobenzoyl-glutamate transporter gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10610 SH03_RS10615 SH03_10620 SH03_RS10615 2145276 2145470 - hypothetical protein gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10615 SH03_RS10620 SH03_10625 SH03_RS10620 2145383 2146828 - p-aminobenzoyl-glutamate hydrolase subunit B gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10620 SH03_RS10625 SH03_10630 SH03_RS10625 2146828 2148138 - p-aminobenzoyl-glutamate hydrolase subunit A gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10625 SH03_RS10630 SH03_10635 SH03_RS10630 2148314 2149222 + transcriptional regulator gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10630 SH03_RS10635 SH03_RS10635 SH03_RS10635 2149294 2149404 - glutamate decarboxylase gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10635 SH03_RS10640 SH03_10645 SH03_RS10640 2149552 2150115 + DNA endonuclease SmrA gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10640 SH03_RS10645 SH03_10650 SH03_RS10645 2150136 2151368 - diguanylate cyclase gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10645 SH03_RS10650 SH03_10655 zntB zntB 2151623 2152606 + zinc transporter ZntB gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10650 SH03_RS10655 SH03_10660 SH03_RS10655 2152881 2153054 + hypothetical protein gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10655 SH03_RS10660 SH03_10665 SH03_RS10660 2153084 2154457 + ATP-dependent RNA helicase DbpA exhibits an RNA-dependent ATPase activity%2C specifically stimulated by bacterial 23S rRNA gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10660 SH03_RS10665 SH03_10670 SH03_RS10665 2154586 2155521 - tRNA 2-thiocytidine biosynthesis protein TtcA TtcA%3B YdaO%3B catalyzes the thiolation of cytosine 32 in specific tRNAs%3B forms 2-thiocytidine (s(2)C) gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10665 SH03_RS10670 SH03_10675 SH03_RS10670 2155573 2155713 - integrase gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10670 SH03_RS10675 SH03_10680 SH03_RS10675 2156810 2157025 - Rac prophage%3B conserved protein gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10675 SH03_RS10680 SH03_10685 SH03_RS10680 2157104 2157313 - double-strand break reduction protein Rac prophage gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10680 SH03_RS10685 SH03_10690 lar lar 2157306 2157500 - restriction alleviation and modification enhancement protein seems to be involved in restriction alleviation and enhancement of modification by EcoKI%2C but not in restriction alleviation of type III restriction systems%3B Rac prophage gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10685 SH03_RS10690 SH03_10695 recT recT 2157557 2158366 - DNA recombination protein RecT gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10690 SH03_RS10695 SH03_10700 SH03_RS10695 2158359 2160959 - exodeoxyribonuclease 8 The RecE (also known as exonuclease VIII) pathway is an alternative pathway for the initiation of homologous recombination in Escherichia coli. The RecE pathway is activated in recB%2C recC sbcA (suppressors of recB and recC) mutants. Activation of the RecE pathway results in the production of at least two phage proteins relevant for recombinational repair. RecE is a duplex DNA-specific exonuclease which produces 3' overhangs in duplex DNA by preferentially degrading the 5'-ending strands. Recombinational repair of E.coli chromosomal DNA involves as well other proteins: RecA%2C RecF%2C RecJ%2C RecO%2C RecR%2C and RuvC. gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10695 SH03_RS10700 SH03_10705 SH03_RS10700 2161061 2161336 - protein RacC Rac prophage hypothetical protein gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10700 SH03_RS10705 SH03_10710 SH03_RS10705 2161411 2161587 - hypothetical protein gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10705 SH03_RS10710 SH03_10715 kil kil 2161581 2161802 - killing protein KilR Rac prophage Kil protein%3B Kil overexpression leads to morphological defects and inhibits cell division gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10710 SH03_RS10715 SH03_10720 SH03_RS10715 2162244 2162732 + superinfection exclusion protein B gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10715 SH03_RS10720 SH03_10725 SH03_RS10720 2163338 2163814 - Rac prophage repressor gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10720 SH03_RS10725 SH03_10730 SH03_RS10725 2163938 2164234 + transcriptional regulator gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10725 SH03_RS10730 SH03_10735 SH03_RS10730 2164257 2164679 + Rac prophage%3B uncharacterized protein gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10730 SH03_RS10735 SH03_10740 SH03_RS10735 2164692 2165549 + Rac prophage%3B conserved protein gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10735 SH03_RS10740 SH03_10745 SH03_RS10740 2165556 2166302 + Rac prophage%3B DNA replication protein gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10740 SH03_RS10745 SH03_RS10745 SH03_RS10745 2166325 2166777 + hypothetical protein gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10745 SH03_RS10750 SH03_10755 SH03_RS10750 2166768 2167217 + endopeptidase gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10750 SH03_RS10755 SH03_10760 SH03_RS10755 2167355 2168812 + Trk system potassium uptake protein TrkG gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10755 SH03_RS10760 SH03_10765 SH03_RS10760 2168949 2169212 + Rac prophage%3B conserved protein gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10760 SH03_RS10765 SH03_10770 SH03_RS10765 2169193 2169552 + hypothetical protein gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10765 SH03_RS10770 SH03_10775 SH03_RS10770 2169660 2169860 + hypothetical protein gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10770 SH03_RS10775 SH03_10780 SH03_RS10775 2170026 2171054 + hypothetical protein gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10775 SH03_RS10780 SH03_RS10780 SH03_RS10780 2170961 2171176 + enterobacterial Ail/Lom family protein gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10780 SH03_RS10785 SH03_10790 SH03_RS10785 2171318 2172298 - transposase gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10785 SH03_RS10790 SH03_RS10790 SH03_RS10790 2172368 2172556 + enterobacterial Ail/Lom family protein gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10790 SH03_RS10795 SH03_10800 SH03_RS10795 2172557 2172730 - hypothetical protein gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10795 SH03_RS10800 SH03_10805 SH03_RS10800 2173118 2173855 - hypothetical protein gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10800 SH03_RS10805 SH03_10810 SH03_RS10805 2173986 2175983 + membrane protein gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10805 SH03_RS10810 SH03_10815 SH03_RS10810 2175983 2176558 + Tail fiber assembly protein homolog from lambdoid prophage Rac gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10810 SH03_RS10815 SH03_10820 SH03_RS10815 2176656 2177246 - Rac prophage%3B site-specific recombinase gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10815 SH03_RS10820 SH03_10825 SH03_RS10820 2177563 2177796 - cold-shock protein gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10820 SH03_RS10825 SH03_10830 SH03_RS10825 2178757 2179191 - universal stress protein F gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10825 SH03_RS10830 SH03_10835 SH03_RS10830 2179332 2180465 - outer membrane protein N allows for ions and hydrophilic solutes to cross the outer membrane gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10830 SH03_RS10835 SH03_10840 SH03_RS10835 2180832 2184356 - pyruvate-flavodoxin oxidoreductase gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10835 SH03_RS10840 SH03_10845 SH03_RS10840 2184630 2184896 + DUF333 domain-containing protein gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10840 SH03_RS10845 SH03_10850 SH03_RS10845 2184893 2185315 - heat-shock protein HslJ gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10845 SH03_RS10850 SH03_10855 SH03_RS10850 2185426 2186415 - lactate dehydrogenase fermentative%3B catalyzes the formationof pyruvate from lactate gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10850 SH03_RS10855 SH03_RS10855 SH03_RS10855 2186623 2189202 + hypothetical protein gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10855 SH03_RS10860 SH03_10865 SH03_RS10860 2189259 2189444 + lipoprotein gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10860 SH03_RS10865 SH03_10870 SH03_RS10865 2189452 2189778 + DUF1318 domain-containing protein gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10865 SH03_RS10870 SH03_10875 SH03_RS10870 2189950 2190855 - transcriptional activator FeaR activator of genes involved in phenylacetic acid catabolism gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10870 SH03_RS10875 SH03_10880 SH03_RS10875 2191091 2192590 + phenylacetaldehyde dehydrogenase gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10875 SH03_RS10880 SH03_10885 tynA tynA 2192648 2194921 - primary amine oxidase catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10880 SH03_RS10885 SH03_10890 SH03_RS10885 2195169 2197214 - bifunctional protein PaaZ catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10885 SH03_RS10890 SH03_10895 paaA paaA 2197499 2198428 + 1%2C2-phenylacetyl-CoA epoxidase subunit A with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10890 SH03_RS10895 SH03_10900 paaB paaB 2198440 2198727 + 1%2C2-phenylacetyl-CoA epoxidase subunit B with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA%3B involved in phenylacetate degradation gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10895 SH03_RS10900 SH03_10905 SH03_RS10900 2198736 2199482 + 1%2C2-phenylacetyl-CoA epoxidase subunit C gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10900 SH03_RS10905 SH03_10910 SH03_RS10905 2199497 2199994 + 1%2C2-phenylacetyl-CoA epoxidase gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10905 SH03_RS10910 SH03_10915 SH03_RS10910 2200002 2201072 + 1%2C2-phenylacetyl-CoA epoxidase subunit E gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10910 SH03_RS10915 SH03_10920 SH03_RS10915 2201069 2201836 + 2%2C3-dehydroadipyl-CoA hydratase gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10915 SH03_RS10920 SH03_10925 SH03_RS10920 2201836 2202624 + 1%2C2-epoxyphenylacetyl-CoA isomerase Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10920 SH03_RS10925 SH03_10930 SH03_RS10925 2202626 2204053 + 3-hydroxyadipyl-CoA dehydrogenase gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10925 SH03_RS10930 SH03_10935 SH03_RS10930 2204043 2204465 + acyl-CoA thioesterase gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10930 SH03_RS10935 SH03_10940 SH03_RS10935 2204465 2205670 + 3-oxoadipyl-CoA/3-oxo-5%2C6-dehydrosuberyl-CoA thiolase catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10935 SH03_RS10940 SH03_10945 SH03_RS10940 2205697 2207010 + phenylacetate-CoA ligase gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10940 SH03_RS10945 SH03_10950 SH03_RS10945 2207111 2208061 + transcriptional regulator gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10945 SH03_RS10950 SH03_10955 SH03_RS10950 2208043 2208633 + phenylacetic acid degradation protein PaaY involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10950 SH03_RS10955 SH03_RS10955 SH03_RS10955 2208964 2211489 + hypothetical protein gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10955 SH03_RS10960 SH03_10965 SH03_RS10960 2211493 2212398 - integrase gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10960 SH03_RS10965 SH03_10970 SH03_RS10965 2212356 2212721 - transposase represses IS2 gene transcription gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10965 SH03_RS10970 SH03_10975 SH03_RS10970 2212930 2214081 + transposase gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10970 SH03_RS10975 SH03_10980 SH03_RS10975 2214262 2217585 + autotransporter subunit beta gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10975 SH03_RS10980 SH03_10985 SH03_RS10980 2217793 2218653 + oxidoreductase gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10980 SH03_RS10985 SH03_10990 SH03_RS10985 2218716 2221022 + hypothetical protein gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10985 SH03_RS10990 SH03_10995 SH03_RS10990 2221193 2221798 + hypothetical protein gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10990 SH03_RS10995 SH03_11000 SH03_RS10995 2221798 2222694 + CDP-diglyceride synthase gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS10995 SH03_RS11000 SH03_11005 SH03_RS11000 2222710 2224467 + esterase gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11000 SH03_RS11005 SH03_11010 SH03_RS11005 2224457 2225773 + hypothetical protein gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11005 SH03_RS11010 SH03_11015 SH03_RS11010 2225827 2226432 - FMN-dependent NADH-azoreductase FMN-dependent%3B requires NADH%3B catalyzes the cleavage of azo bond in aromatic azo compounds gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11010 SH03_RS11015 SH03_11020 SH03_RS11015 2226633 2230535 + ATP-dependent RNA helicase HrpA involved in the post-transcriptional processing of the daa operon mRNA%2C which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11015 SH03_RS11020 SH03_11025 SH03_RS11020 2230807 2231607 + hypothetical protein gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11020 SH03_RS11025 SH03_11030 SH03_RS11025 2231804 2233243 + lactaldehyde dehydrogenase NAD-linked gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11025 SH03_RS11030 SH03_11035 SH03_RS11030 2233285 2233536 - glyceraldehyde-3-phosphate dehydrogenase gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11030 SH03_RS11035 SH03_11040 SH03_RS11035 2233533 2233910 - glyceraldehyde-3-phosphate dehydrogenase gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11035 SH03_RS11040 SH03_11045 SH03_RS11040 2234169 2234285 - glyceraldehyde-3-phosphate dehydrogenase gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11040 SH03_RS11045 SH03_11050 SH03_RS11045 2234474 2235004 + cytochrome B561 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11045 SH03_RS11050 SH03_11055 SH03_RS11050 2235249 2235422 + periplasmic protein gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11050 SH03_RS11055 SH03_11060 SH03_RS11055 2235494 2235643 - protein HokB gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11055 SH03_RS11060 SH03_11065 SH03_RS11060 2236042 2237682 + methyl-accepting chemotaxis protein III gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11060 SH03_RS11065 SH03_11070 SH03_RS11065 2237720 2238643 - transcriptional regulator gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11065 SH03_RS11070 SH03_11075 SH03_RS11070 2238860 2240203 + metalloenzyme gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11070 SH03_RS11075 SH03_11080 mdoD mdoD 2240464 2242083 + glucan biosynthesis protein D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11075 SH03_RS11080 SH03_11085 SH03_RS11080 2242004 2242207 - hypothetical protein gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11080 SH03_RS11085 SH03_11090 SH03_RS11085 2242223 2242447 + hypothetical protein gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11085 SH03_RS11090 SH03_11095 SH03_RS11090 2242510 2243049 + ribosomal-protein-serine acetyltransferase gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11090 SH03_RS11095 SH03_11100 SH03_RS11095 2243041 2244021 - hypothetical protein gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11095 SH03_RS11100 SH03_11105 SH03_RS11100 2244133 2245137 + tellurite resistance protein TehA gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11100 SH03_RS11105 SH03_11110 SH03_RS11105 2245134 2245727 + tellurite methyltransferase with TehA confers resistance to tellurite gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11105 SH03_RS11110 SH03_11115 SH03_RS11110 2246029 2246697 + lipoprotein gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11110 SH03_RS11115 SH03_RS11115 SH03_RS11115 2246730 2246933 + TetR family transcriptional regulator gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11115 SH03_RS11120 SH03_11125 SH03_RS11120 2246934 2247221 - transposase gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11120 SH03_RS11125 SH03_11130 SH03_RS11125 2247289 2248437 + transposase gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11125 SH03_RS11130 SH03_11135 SH03_RS11130 2248477 2249652 - hypothetical protein gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11130 SH03_RS11135 SH03_11140 SH03_RS11135 2249744 2250280 + transcriptional regulator gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11135 SH03_RS11140 SH03_11145 SH03_RS11140 2250353 2252314 + peptidase gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11140 SH03_RS11145 SH03_11150 SH03_RS11145 2252406 2252576 - hypothetical protein gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11145 SH03_RS11150 SH03_11155 SH03_RS11150 2252858 2253034 + mRNA interferase HicA gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11150 SH03_RS11155 SH03_11160 SH03_RS11155 2253059 2253496 + antitoxin gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11155 SH03_RS11160 SH03_11165 SH03_RS11160 2253575 2254981 + transcriptional regulator gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11160 SH03_RS11165 SH03_11170 SH03_RS11165 2255226 2256371 + ABC transporter substrate-binding protein gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11165 SH03_RS11170 SH03_11175 SH03_RS11170 2256389 2257402 + ABC transporter ATPase gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11170 SH03_RS11175 SH03_11180 SH03_RS11175 2257403 2258344 + ABC transporter permease gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11175 SH03_RS11180 SH03_11185 SH03_RS11180 2258334 2259128 + ABC transporter permease gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11180 SH03_RS11185 SH03_11190 SH03_RS11185 2259150 2260574 + gamma-aminobutyraldehyde dehydrogenase catalyzes the formation of 4-aminobutanoate from 4-aminobutanal%3B involved in putrescine degradation gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11185 SH03_RS11190 SH03_11195 SH03_RS11190 2260605 2260802 + hypothetical protein gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11190 SH03_RS11195 SH03_11200 SH03_RS11195 2260961 2261134 + DUF2566 domain-containing protein gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11195 SH03_RS11200 SH03_11205 SH03_RS11200 2261220 2261453 + hypothetical protein gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11200 SH03_RS11205 SH03_11210 SH03_RS11205 2261454 2261903 - hypothetical protein gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11205 SH03_RS11210 SH03_11215 SH03_RS11210 2261900 2262418 - L-amino acid N-acyltransferase MnaT gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11210 SH03_RS11215 SH03_11220 SH03_RS11215 2262599 2263636 + NADPH-dependent curcumin reductase gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11215 SH03_RS11220 SH03_11225 SH03_RS11220 2263834 2264499 + transcriptional regulator gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11220 SH03_RS11225 SH03_11230 SH03_RS11225 2264535 2266637 - TonB-dependent receptor gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11225 SH03_RS11230 SH03_11235 SH03_RS11230 2266879 2267940 + ATP-binding protein%2C periplasmic%2C function unknown gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11230 SH03_RS11235 SH03_11240 SH03_RS11235 2268053 2269552 - L-asparagine permease involved in the transporte of L-asparagine gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11235 SH03_RS11240 SH03_11245 SH03_RS11240 2269819 2270436 + glutathione S-transferase gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11240 SH03_RS11245 SH03_11250 SH03_RS11245 2270512 2270724 + IPR020099 family protein gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11245 SH03_RS11250 SH03_11255 SH03_RS11250 2271711 2273510 + type IV secretion protein Rhs gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11250 SH03_RS11255 SH03_11260 SH03_RS11255 2273494 2273976 + immunity protein for RhsE gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11255 SH03_RS11260 SH03_11265 SH03_RS11260 2274158 2274904 + hypothetical protein gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11260 SH03_RS11265 SH03_11270 SH03_RS11265 2275388 2276524 + hypothetical protein gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11265 SH03_RS11270 SH03_11275 SH03_RS11270 2276624 2276857 + tautomerase PptA 4-OT%3B member of subfamily 5%3B forms a dimer%3B the function in the Escherichia coli cell is unknown gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11270 SH03_RS11275 SH03_11280 SH03_RS11275 2276854 2277423 - flavin reductase like-protein gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11275 SH03_RS11280 SH03_11285 SH03_RS11280 2277596 2278441 + N-hydroxyarylamine O-acetyltransferase catalyzes the addition of the acetyl moity of acetyl-CoA to an N-hydroxy-arylamine to form an N-acetoxyarylamine gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11280 SH03_RS11285 SH03_11290 SH03_RS11285 2278537 2279430 - PhzC-PhzF family protein gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11285 SH03_RS11290 SH03_11295 narI narI 2279509 2280189 - respiratory nitrate reductase subunit gamma with NarGJH catalyzes the reduction of nitrate%3B the gamma subunit localizes NarGHI to the membrane%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11290 SH03_RS11295 SH03_11300 SH03_RS11295 2280186 2280881 - nitrate reductase molybdenum cofactor assembly chaperone NarW delta subunit of nitrate reductase 1%3B chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1 gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11295 SH03_RS11300 SH03_11305 narH narH 2280881 2282425 - nitrate reductase subunit beta with NarGJI catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11300 SH03_RS11305 SH03_11310 narZ narZ 2282422 2286162 - respiratory nitrate reductase 2 alpha chain with NarYV catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli%3B expression of nitrate reductase Z is not dependent on nitrate levels gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11305 SH03_RS11310 SH03_11315 SH03_RS11310 2286244 2287632 - nitrate/nitrite transporter NarU involved in the transport of nitrate and nitrite gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11310 SH03_RS11315 SH03_RS11315 SH03_RS11315 2287956 2289286 - hypothetical protein gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11315 SH03_RS11320 SH03_11325 SH03_RS11320 2289310 2289600 - lipoprotein gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11320 SH03_RS11325 SH03_11330 SH03_RS11325 2289860 2290684 - aromatic amino acid exporter gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11325 SH03_RS11330 SH03_11335 SH03_RS11330 2290973 2291560 + sulfate ABC transporter substrate-binding protein gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11330 SH03_RS11335 SH03_11340 SH03_RS11335 2291609 2294020 + formate dehydrogenase subunit alpha gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11335 SH03_RS11340 SH03_11345 SH03_RS11340 2294033 2294917 + formate dehydrogenase beta subunit%3B involved in the use of formate as an electron donor during aerobic respiration%3B acts to transfer electrons from the major(alpha subunit) to the cytochrome b556(gamma subunit) gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11340 SH03_RS11345 SH03_11350 SH03_RS11345 2294910 2295563 + formate dehydrogenase nitrate-inducible cytochrome b556(Fdn) subunit cytochrome b556(FDO) component%3B heme containing gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11345 SH03_RS11350 SH03_11355 SH03_RS11350 2295970 2296254 - transcriptional regulator gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11350 SH03_RS11355 SH03_11360 adhP adhP 2296400 2297410 - ethanol-active dehydrogenase/acetaldehyde-active reductase similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11355 SH03_RS11360 SH03_11365 SH03_RS11360 2297544 2299241 - NAD-dependent malic enzyme gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11360 SH03_RS11365 SH03_11370 rpsV rpsV 2299397 2299534 - stationary-phase-induced ribosome-associated protein protein D%3B stationary-phase-induced ribosome-associated%3B in Escherichia coli this protein becomes associated with the ribosome%3B expression increases during stationary phase gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11365 SH03_RS11370 SH03_11375 SH03_RS11370 2299636 2299851 - protein bdm gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11370 SH03_RS11375 SH03_11380 SH03_RS11375 2300196 2300627 + peroxiredoxin OsmC gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11375 SH03_RS11380 SH03_11385 SH03_RS11380 2300683 2301609 - peptide ABC transporter ATP-binding protein gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11380 SH03_RS11385 SH03_11390 SH03_RS11385 2301602 2302588 - peptide ABC transporter ATP-binding protein gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11385 SH03_RS11390 SH03_11395 SH03_RS11390 2302585 2303481 - peptide ABC transporter permease gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11390 SH03_RS11395 SH03_11400 SH03_RS11395 2303478 2304500 - peptide ABC transporter permease gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11395 SH03_RS11400 SH03_11405 SH03_RS11400 2304502 2306052 - peptide ABC transporter substrate-binding protein gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11400 SH03_RS11405 SH03_11410 SH03_RS11405 2306066 2306647 - D-alanyl-D-alanine dipeptidase catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent%3B involved in peptidoglycan synthesis gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11405 SH03_RS11410 SH03_11415 SH03_RS11410 2306905 2309328 - diguanylate phosphodiesterase heme-regulated phosphodiesterase with phosphodiesterase activity with cGMP%3B cold- and stationary phase-induced bioflim regulator%3B oxygen sensor gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11410 SH03_RS11415 SH03_11420 SH03_RS11415 2309329 2310711 - diguanylate cyclase gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11415 SH03_RS11420 SH03_11425 SH03_RS11420 2311075 2312229 - hypothetical protein gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11420 SH03_RS11425 SH03_11430 SH03_RS11425 2312525 2314060 - glutamate/gamma-aminobutyrate antiporter gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11425 SH03_RS11430 SH03_11435 SH03_RS11430 2314216 2315616 - glutamate decarboxylase beta gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11430 SH03_RS11435 SH03_11440 SH03_RS11435 2315627 2315725 - hypothetical protein gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11435 SH03_RS11440 SH03_11445 SH03_RS11440 2315978 2318761 - zinc protease gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11440 SH03_RS11445 SH03_11450 SH03_RS11445 2318818 2321190 - TonB-dependent receptor gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11445 SH03_RS11450 SH03_11455 SH03_RS11450 2321228 2322913 - ABC transporter ATP-binding protein gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11450 SH03_RS11455 SH03_11460 SH03_RS11455 2323204 2324361 - anaerobic sulfatase maturase gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11455 SH03_RS11460 SH03_11465 SH03_RS11460 2324413 2326095 - Ser-type periplasmic non-aryl sulfatase gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11460 SH03_RS11465 SH03_11470 SH03_RS11465 2326497 2327258 - transcriptional regulator regulates the cellular response to acid resistance gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11465 SH03_RS11470 SH03_11475 SH03_RS11470 2327333 2327530 - two-component-system connector protein SafA gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11470 SH03_RS11475 SH03_11480 SH03_RS11475 2327778 2330057 - hypothetical protein in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell%3B involved with increased resistance to low pH%3B member of the prokaryotic molybdopterin-containing oxidoreductase family gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11475 SH03_RS11480 SH03_11485 SH03_RS11480 2330391 2331305 - fimbrial-like adhesin protein gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11480 SH03_RS11485 SH03_11490 SH03_RS11485 2331364 2331867 - fimbrial-like adhesin protein gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11485 SH03_RS11490 SH03_11495 SH03_RS11490 2331880 2332410 - fimbrial-like adhesin protein gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11490 SH03_RS11495 SH03_11500 SH03_RS11495 2332424 2333572 - fimbrial protein FimD gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11495 SH03_RS11500 SH03_11505 SH03_RS11500 2333928 2334107 - transcriptional regulator gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11500 SH03_RS11505 SH03_11510 SH03_RS11505 2334425 2335747 - serine/threonine protein kinase gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11505 SH03_RS11510 SH03_11515 SH03_RS11510 2335747 2336013 - antitoxin HipB gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11510 SH03_RS11515 SH03_11520 SH03_RS11515 2336236 2337636 - hypothetical protein gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11515 SH03_RS11520 SH03_11525 SH03_RS11520 2337680 2341657 - hypothetical protein gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11520 SH03_RS11525 SH03_11530 SH03_RS11525 2342188 2343780 - autoinducer 2 kinase LsrK gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11525 SH03_RS11530 SH03_11535 SH03_RS11530 2343859 2344812 - LsrR family transcriptional regulator regulates the transcription of lsr genes%3B involved in autoinducer 2 uptake%2C biofilm formation and stress responses gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11530 SH03_RS11535 SH03_11540 SH03_RS11535 2345061 2346596 + autoinducer 2 import ATP-binding protein LsrA gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11535 SH03_RS11540 SH03_11545 SH03_RS11540 2346590 2347618 + autoinducer 2 import system permease LsrC with LsrADB is involved in the transport of autoindiuce 2 gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11540 SH03_RS11545 SH03_11550 SH03_RS11545 2347618 2348610 + autoinducer 2 import system permease LsrD gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11545 SH03_RS11550 SH03_11555 SH03_RS11550 2348622 2349644 + autoinducer 2-binding protein LsrB with lsrACD is involved in the transport of autoinducer 2 into the cell gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11550 SH03_RS11555 SH03_11560 SH03_RS11555 2349671 2350546 + autoinducer-2 (AI-2) aldolase involved in autoinducer 2 transport and processing gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11555 SH03_RS11560 SH03_11565 SH03_RS11560 2350570 2350860 + autoinducer 2-degrading protein LsrG gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11560 SH03_RS11565 SH03_11570 SH03_RS11565 2350917 2351675 + trans-aconitate 2-methyltransferase catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11565 SH03_RS11570 SH03_11575 SH03_RS11570 2351679 2352593 - hypothetical protein gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11570 SH03_RS11575 SH03_RS11575 SH03_RS11575 2352543 2352743 + hypothetical protein gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11575 SH03_RS11580 SH03_11585 SH03_RS11580 2352800 2354251 - altronate oxidoreductase catalyzes the formation of D-tagaturonate from D-altronate gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11580 SH03_RS11585 SH03_11590 SH03_RS11585 2354478 2355425 - diguanylate cyclase gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11585 SH03_RS11590 SH03_11595 SH03_RS11590 2355537 2355896 - DUF4186 domain-containing protein gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11590 SH03_RS11595 SH03_11600 SH03_RS11595 2355896 2356822 - glutaminase 2 catalyzes the formation of glutamate from glutamine gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11595 SH03_RS11600 SH03_11605 SH03_RS11600 2356886 2358274 - succinate semialdehyde dehydrogenase [NAD(P)+] Sad gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11600 SH03_RS11605 SH03_11610 SH03_RS11605 2358375 2359256 + transcriptional regulator gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11605 SH03_RS11610 SH03_11615 SH03_RS11610 2359334 2360449 + hypothetical protein gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11610 SH03_RS11615 SH03_11620 SH03_RS11615 2360599 2361789 + sugar efflux transporter gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11615 SH03_RS11620 SH03_11625 SH03_RS11620 2361814 2362479 - membrane protein gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11620 SH03_RS11625 SH03_11630 SH03_RS11625 2362691 2363125 + MarR family transcriptional regulator Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11625 SH03_RS11630 SH03_11635 SH03_RS11630 2363139 2363528 + MDR efflux pump AcrAB transcriptional activator MarA transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype%3B also activates sodA%2C zwf and micF gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11630 SH03_RS11635 SH03_11640 SH03_RS11635 2363560 2363778 + multiple antibiotic resistance protein MarB gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11635 SH03_RS11640 SH03_11645 SH03_RS11640 2363809 2364708 - amino acid metabolite efflux pump gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11640 SH03_RS11645 SH03_11650 SH03_RS11645 2364903 2366090 + transporter YdeF%3B uncharacterized member of the major facilitator superfamily (MFS) of transporters gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11645 SH03_RS11650 SH03_11655 SH03_RS11650 2366217 2366312 + hypothetical protein gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11650 SH03_RS11655 SH03_11660 SH03_RS11655 2366531 2367421 - diguanylate cyclase required for pgaD induction gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11655 SH03_RS11660 SH03_11665 SH03_RS11660 2367676 2368068 - hydrogen peroxide resistance protein gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11660 SH03_RS11665 SH03_11670 SH03_RS11665 2368344 2368862 + hypothetical protein gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11665 SH03_RS11670 SH03_11675 SH03_RS11670 2368906 2370951 - peptidyl-dipeptidase dcp gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11670 SH03_RS11675 SH03_11680 SH03_RS11675 2371088 2371834 + NADP-dependent 3-hydroxy acid dehydrogenase YdfG NADP(+)-dependent%3B catalyzes the formation of 3-hydroxypropionate from the toxic malonic semialdehyde%2C catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine%3B can also use 3-hydroxybutyrate%2C 3-hydroxy-isobutyrate%2C D-threonine%2C L-allo-threonine%2CD-serine gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11675 SH03_RS11680 SH03_11685 SH03_RS11680 2371923 2372609 + transcriptional regulator gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11680 SH03_RS11685 SH03_11690 SH03_RS11685 2372786 2372989 + hypothetical protein gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11685 SH03_RS11690 SH03_11695 SH03_RS11690 2373024 2374484 - NAD-dependent D-mannonate oxidoreductase gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11690 SH03_RS11695 SH03_11700 SH03_RS11695 2374573 2375856 - transporter gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11695 SH03_RS11700 SH03_11705 SH03_RS11700 2376643 2376876 + cold-shock protein gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11700 SH03_RS11705 SH03_11710 SH03_RS11705 2377193 2377783 + Qin prophage%3B site-specific recombinase gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11705 SH03_RS11710 SH03_11715 SH03_RS11710 2377881 2378456 - Tail fiber assembly protein homolog from lambdoid prophage Qin gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11710 SH03_RS11715 SH03_11720 SH03_RS11715 2378456 2379418 - Side tail fiber protein homolog from lambdoid prophage Qin gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11715 SH03_RS11720 SH03_11725 SH03_RS11720 2379369 2379938 - protein convertase gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11720 SH03_RS11725 SH03_11730 SH03_RS11725 2380327 2380560 + hypothetical protein gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11725 SH03_RS11730 SH03_11735 SH03_RS11730 2380618 2381028 + Qin prophage%3B uncharacterized protein gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11730 SH03_RS11735 SH03_11740 SH03_RS11735 2381180 2381353 - protein GnsB gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11735 SH03_RS11740 SH03_11745 SH03_RS11740 2381525 2381701 - hypothetical protein gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11740 SH03_RS11745 SH03_11750 SH03_RS11745 2382026 2382238 - cold-shock protein CspI gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11745 SH03_RS11750 SH03_11755 SH03_RS11750 2382601 2383098 - Rz-like protein%2C Qin prophage gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11750 SH03_RS11755 SH03_11760 SH03_RS11755 2383095 2383628 - lysozyme from lambdoid prophage Qin gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11755 SH03_RS11760 SH03_11765 SH03_RS11760 2383625 2383936 - Qin prophage%3B uncharacterized protein gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11760 SH03_RS11765 SH03_11770 SH03_RS11765 2383941 2384156 - Lysis protein S homolog from lambdoid prophage Qin gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11765 SH03_RS11770 SH03_11775 SH03_RS11770 2384910 2385125 - cold-shock protein CspB gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11770 SH03_RS11775 SH03_11780 SH03_RS11775 2385426 2385638 + cold-shock protein CspF gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11775 SH03_RS11780 SH03_11785 SH03_RS11780 2386060 2386812 - Antitermination protein Q homolog from lambdoid prophage Qin gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11780 SH03_RS11785 SH03_11790 SH03_RS11785 2386826 2387875 - hypothetical protein gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11785 SH03_RS11790 SH03_11795 SH03_RS11790 2387877 2388155 - hypothetical protein gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11790 SH03_RS11795 SH03_11800 SH03_RS11795 2388222 2388473 - Qin prophage%3B uncharacterized protein gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11795 SH03_RS11800 SH03_11805 SH03_RS11800 2388690 2388845 - protein HokD gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11800 SH03_RS11805 SH03_11810 SH03_RS11805 2388917 2389204 - mRNA interferase RelE gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11805 SH03_RS11810 SH03_11815 SH03_RS11810 2389204 2389443 - antitoxin RelB Qin prophage%3B bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11810 SH03_RS11815 SH03_11820 SH03_RS11815 2389976 2390308 + protein FlxA gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11815 SH03_RS11820 SH03_RS11820 SH03_RS11820 2390910 2391207 - hypothetical protein gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11820 SH03_RS11825 SH03_11830 SH03_RS11825 2391191 2391421 - repressor protein of division inhibition gene dicB gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11825 SH03_RS11830 SH03_11835 SH03_RS11830 2391505 2391912 + transcriptional regulator The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC%2C but its specific role in cellular replication and mode of action are still unknown. gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11830 SH03_RS11835 SH03_11840 SH03_RS11835 2392079 2392234 + Qin prophage%3B uncharacterized protein gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11835 SH03_RS11840 SH03_11845 SH03_RS11840 2392394 2392612 + hypothetical protein gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11840 SH03_RS11845 SH03_11850 SH03_RS11845 2392616 2392909 - hypothetical protein gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11845 SH03_RS11850 SH03_11855 SH03_RS11850 2393180 2393368 + division inhibition protein DicB gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11850 SH03_RS11855 SH03_11860 SH03_RS11855 2393365 2393556 + hypothetical protein gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11855 SH03_RS11860 SH03_11865 SH03_RS11860 2393868 2394179 - cell surface protein gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11860 SH03_RS11865 SH03_RS11865 SH03_RS11865 2394383 2395108 + transposase gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11865 SH03_RS11870 SH03_11875 SH03_RS11870 2395083 2396279 + integrase gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11870 SH03_RS11875 SH03_11880 SH03_RS11875 2396467 2397486 - starvation-sensing protein RspB gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11875 SH03_RS11880 SH03_11885 SH03_RS11880 2397498 2398712 - starvation-sensing protein RspA starvation-sensing protein%3B maybe involved in homoserine lactone degradation gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11880 SH03_RS11885 SH03_11890 SH03_RS11885 2398918 2399244 - membrane protein gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11885 SH03_RS11890 SH03_11895 SH03_RS11890 2399379 2399720 + hypothetical protein gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11890 SH03_RS11895 SH03_11900 SH03_RS11895 2399755 2400315 + spermidine N(1)-acetyltransferase catalyzes the formation of N(1)- and N(8)-acetylspermidine from spermidine gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11895 SH03_RS11900 SH03_11905 SH03_RS11900 2400318 2401064 - lipoprotein gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11900 SH03_RS11905 SH03_11910 SH03_RS11905 2401136 2401441 + DUF1161 domain-containing protein gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11905 SH03_RS11910 SH03_11915 SH03_RS11910 2401640 2404066 + selenate reductase periplasmic gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11910 SH03_RS11915 SH03_11920 SH03_RS11915 2404154 2406550 + dimethyl sulfoxide reductase subunit A gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11915 SH03_RS11920 SH03_11925 SH03_RS11920 2406561 2407178 + dimethyl sulfoxide reductase oxidoreductase%2C Fe-S subunit%3B terminal electron transfer protein for the reduction of DMSO gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11920 SH03_RS11925 SH03_11930 SH03_RS11925 2407180 2408034 + dimethyl sulfoxide reductase gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11925 SH03_RS11930 SH03_11935 SH03_RS11930 2408077 2408691 + Tat proofreading chaperone DmsD binds to the twin-arginine signal peptides of certain proteins%2C including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11930 SH03_RS11935 SH03_11940 SH03_RS11935 2408886 2410142 + voltage-gated ClC-type chloride channel ClcB gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11935 SH03_RS11940 SH03_11945 SH03_RS11940 2410095 2410790 - ATP-dependent dethiobiotin synthetase BioD 2 DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11940 SH03_RS11945 SH03_11950 SH03_RS11945 2410915 2412135 - protein mlc mlc%2C controls the expression of genes involved in the phosphotransferase and phosphoenolpyruvate systems%2C regulates genes involved in the uptake of sugars gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11945 SH03_RS11950 SH03_11955 SH03_RS11950 2412270 2413163 - LysR family transcriptional regulator gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11950 SH03_RS11955 SH03_11960 SH03_RS11955 2413270 2414523 + transporter gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11955 SH03_RS11960 SH03_11965 SH03_RS11960 2414920 2415255 + hypothetical protein required for growth and survival under moderately acid conditions gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11960 SH03_RS11965 SH03_11970 SH03_RS11965 2415348 2415431 + stationary phase-induced protein gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11965 SH03_RS11970 SH03_11975 SH03_RS11970 2415531 2416352 + peptidase gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11970 SH03_RS11975 SH03_11980 SH03_RS11975 2416391 2416720 - spermidine export protein MdtI with MdtJ is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11975 SH03_RS11980 SH03_11985 SH03_RS11980 2416707 2417072 - spermidine export protein MdtJ with MdtI is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11980 SH03_RS11985 SH03_11990 tqsA tqsA 2417484 2418518 + AI-2 transporter TqsA transport of quorum-sensing signal%3B mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11985 SH03_RS11990 SH03_11995 pntB pntB 2418543 2419931 - NAD(P) transhydrogenase subunit beta catalyzes reversible transfer of hydride ion equivalent between NAD and NADP%3B membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane%3B forms a tetramer composed of two alpha and 2 beta subunits%3B AB-stereospecific enzyme gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11990 SH03_RS11995 SH03_12000 pntA pntA 2419942 2421474 - NAD(P) transhydrogenase subunit alpha forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane%3B involved in catalyzing transfer of hydride ion equivalents between NAD and NADP%3B stereospecific (AB-specific)%3B functions as a proton pump by translocating protons from cytoplasm to periplasm gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS11995 SH03_RS12000 SH03_12005 SH03_RS12000 2421998 2422942 + hypothetical protein gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12000 SH03_RS12005 SH03_12010 SH03_RS12005 2423128 2424510 + arginine/ornithine antiporter transporter gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12005 SH03_RS12010 SH03_12015 SH03_RS12010 2424547 2425269 + dihydrofolate reductase FolM gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12010 SH03_RS12015 SH03_12020 SH03_RS12015 2425266 2425601 - membrane protein gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12015 SH03_RS12020 SH03_12025 SH03_RS12020 2425730 2426449 + two-component system response regulator response regulator in two-component regulatory system with RstB gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12020 SH03_RS12025 SH03_12030 SH03_RS12025 2426453 2427754 + two-component system sensor histidine kinase gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12025 SH03_RS12030 SH03_12035 SH03_RS12030 2427830 2428759 + DNA replication terminus site-binding protein binds to DNA replication terminator sequences to prevent passage of replication forks gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12030 SH03_RS12035 SH03_12040 fumC fumC 2428756 2430159 - fumarate hydratase class II class II family (does not require metal)%3B tetrameric enzyme%3B fumarase C%3B reversibly converts (S)-malate to fumarate and water%3B functions in the TCA cycle gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12035 SH03_RS12040 SH03_12045 SH03_RS12040 2430302 2431948 - fumarate hydratase class I%2C aerobic catalyzes the formation of malate from fumerate gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12040 SH03_RS12045 SH03_12050 SH03_RS12045 2432147 2433322 + mannose-6-phosphate isomerase catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12045 SH03_RS12050 SH03_12055 SH03_RS12050 2433423 2434931 + hypothetical protein gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12050 SH03_RS12055 SH03_12060 SH03_RS12055 2435157 2436422 - porin gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12055 SH03_RS12060 SH03_12065 SH03_RS12060 2436461 2437834 - glucuronide carrier protein gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12060 SH03_RS12065 SH03_12070 SH03_RS12065 2437831 2439642 - beta-glucuronidase gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12065 SH03_RS12070 SH03_12075 SH03_RS12070 2440033 2440623 - transcriptional regulator gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12070 SH03_RS12075 SH03_12080 SH03_RS12075 2440844 2441611 - 7-alpha-hydroxysteroid dehydrogenase Acts on the hydroxyl group at position 7 of the steroid frame gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12075 SH03_RS12080 SH03_12085 SH03_RS12080 2441723 2442751 - maltose regulon regulatory protein MalI regulates malXY which are involved in maltose-glucose transport gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12080 SH03_RS12085 SH03_12090 SH03_RS12085 2442926 2444518 + PTS maltose- and glucose EIICB component phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%3B catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane%3B component IIB catalyzes the phosphorylation of the sugar molecule%3B IIC forms the translocation channel and contains the substrate specific binding site gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12085 SH03_RS12090 SH03_12095 SH03_RS12090 2444528 2445700 + protein MalY catalyzes the formation of homocysteine and pyruvate from cystathionine%3B also acts a a negative regulator for the mal regulon but interacting with the transcriptional activator MalT gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12090 SH03_RS12095 SH03_12100 SH03_RS12095 2445804 2446805 + adenosine deaminase gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12095 SH03_RS12100 SH03_12105 SH03_RS12100 2446839 2447879 - oxidoreductase gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12100 SH03_RS12105 SH03_12110 SH03_RS12105 2448122 2448247 + divisome-associated membrane protein Blr gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12105 SH03_RS12110 SH03_12115 SH03_RS12110 2448520 2448735 + nucleoid-associated protein YdgT%3B in E. coli%2C when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC%3B seems to play a role in optimizing the activity of oriC%3B non-essential%3B Hha protein paralog%3B in an hha mutant background%2C cnu is overexpressed and can compensate hha-induced phenotypes gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12110 SH03_RS12115 SH03_12120 SH03_RS12115 2448821 2449261 + hypothetical protein gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12115 SH03_RS12120 SH03_12125 SH03_RS12120 2449338 2449919 + electron transport complex subunit RsxA gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12120 SH03_RS12125 SH03_12130 SH03_RS12125 2449919 2450497 + electron transport complex subunit RsxB part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12125 SH03_RS12130 SH03_12135 SH03_RS12130 2450490 2452712 + electron transporter RsxC part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12130 SH03_RS12135 SH03_12140 rnfD rnfD 2452713 2453771 + electron transport complex subunit RsxD RnfD%3B RsxD%3B required for nitrogen fixation in Rhodobacter capsulatus%3B part of a membrane-bound complex thought to be involved in electron transport to nitrogenase%3B in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12135 SH03_RS12140 SH03_12145 SH03_RS12140 2453775 2454395 + electron transport complex subunit RsxG part of membrane-bound complex hought to be involved in electron transport to nitrogen gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12140 SH03_RS12145 SH03_12150 SH03_RS12145 2454399 2455094 + electron transporter RsxE gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12145 SH03_RS12150 SH03_12155 SH03_RS12150 2455094 2455729 + endonuclease III DNA-(apurinic or apyrimidinic site) lyase%3B has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity%3B removed damaged DNA at cytosines%2C thymines and guanines gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12150 SH03_RS12155 SH03_12160 SH03_RS12155 2455857 2456057 + hypothetical protein gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12155 SH03_RS12160 SH03_12165 tppB tppB 2456340 2457842 + dipeptide and tripeptide permease A mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium%3B member of proton-dependent oligopeptide transport (POT) system family%3B in Escherichia coli this gene is regulated by OmpR although not via osmoregulation gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12160 SH03_RS12165 SH03_12170 SH03_RS12165 2457948 2458553 + glutathione S-transferase gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12165 SH03_RS12170 SH03_12175 SH03_RS12170 2458597 2459457 - pyridoxamine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12170 SH03_RS12175 SH03_12180 SH03_RS12175 2459519 2460793 - tyrosine--tRNA ligase gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12175 SH03_RS12180 SH03_12185 SH03_RS12180 2460922 2461578 - pyridoxine/pyridoxamine 5'-phosphate oxidase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12180 SH03_RS12185 SH03_12190 SH03_RS12185 2461637 2461966 - lysozyme inhibitor MliC%3B membrane-bound lysozyme inhibitor of c-type lysozyme gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12185 SH03_RS12190 SH03_12195 anmK anmK 2462064 2463173 - anhydro-N-acetylmuramic acid kinase catalyzes hydrolysis of 1%2C6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate%3B involved in murein recycling gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12190 SH03_RS12195 SH03_12200 SH03_RS12195 2463447 2463914 + hypothetical protein gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12195 SH03_RS12200 SH03_12205 SH03_RS12200 2463961 2464395 - SlyA family transcriptional regulator Transcription regulator that can both activate or repress expression gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12200 SH03_RS12205 SH03_12210 SH03_RS12205 2464596 2464832 + membrane protein gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12205 SH03_RS12210 SH03_12215 SH03_RS12210 2464835 2465692 + membrane fusion protein (MFP) of YdhJK efflux pump gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12210 SH03_RS12215 SH03_12220 SH03_RS12215 2465692 2467704 + efflux protein (PET) component of YdhJK efflux pump gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12215 SH03_RS12220 SH03_12225 SH03_RS12220 2467705 2468226 - superoxide dismutase [Cu-Zn] SodC%3B copper and zinc binding%3B converts superoxide radicals to hydrogen peroxide and water gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12220 SH03_RS12225 SH03_12230 SH03_RS12225 2468307 2469203 - oxidoreductase gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12225 SH03_RS12230 SH03_12235 SH03_RS12230 2469252 2469491 - DUF1289 domain-containing protein gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12230 SH03_RS12235 SH03_12240 SH03_RS12235 2469594 2470193 + transcriptional regulator represses nemA which is involved in degradation of N-ethylmaleimide gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12235 SH03_RS12240 SH03_12245 SH03_RS12240 2470230 2471327 + N-ethylmaleimide reductase FMN-linked%3B catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12240 SH03_RS12245 SH03_12250 SH03_RS12245 2471408 2471815 + lactoylglutathione lyase Ni-dependent%3B catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12245 SH03_RS12250 SH03_12255 SH03_RS12250 2471918 2472565 + ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12250 SH03_RS12255 SH03_12260 SH03_RS12255 2472658 2477274 + ATP-dependent helicase similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases%3B longest known protein in E. coli gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12255 SH03_RS12260 SH03_12265 SH03_RS12260 2477325 2477672 - glutaredoxin gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12260 SH03_RS12265 SH03_12270 SH03_RS12265 2478006 2478821 + murein DD-endopeptidase MepH gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12265 SH03_RS12270 SH03_12275 SH03_RS12270 2478949 2479530 + superoxide dismutase [Fe] SodB%3B iron binding%3B present under aerobic and anaerobic conditions%3B destroys free radicals gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12270 SH03_RS12275 SH03_12280 SH03_RS12275 2479692 2480861 - transporter gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12275 SH03_RS12280 SH03_12285 SH03_RS12280 2481027 2481116 - stress response membrane gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12280 SH03_RS12285 SH03_12290 SH03_RS12285 2481415 2482440 + PurR family transcriptional regulator binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12285 SH03_RS12290 SH03_12295 SH03_RS12290 2482437 2483369 - LysR family transcriptional regulator gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12290 SH03_RS12295 SH03_12300 SH03_RS12295 2483482 2484693 + Bcr/CflA family drug resistance efflux transporter uncharacterized member of the major facilitator superfamily (MFS) gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12295 SH03_RS12300 SH03_12305 SH03_RS12300 2484984 2486132 + cyclopropane-fatty-acyl-phospholipid synthase catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12300 SH03_RS12305 SH03_12310 SH03_RS12305 2486172 2486813 - riboflavin synthase catalyzes the formation of riboflavin from 6%2C7-dimethyl-8-(1-D-ribityl)lumazine gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12305 SH03_RS12310 SH03_12315 SH03_RS12310 2487028 2488401 + multidrug resistance protein MdtK NorM%3B MdtK%3B functions as a Na(+)/drug antiporter%3B inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12310 SH03_RS12315 SH03_12320 SH03_RS12315 2488442 2489698 - autotransporter adhesin-related protein gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12315 SH03_RS12320 SH03_12325 SH03_RS12320 2490006 2490082 + tRNA-Val tRNA gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12320 SH03_RS12325 SH03_12330 SH03_RS12325 2490087 2490163 + tRNA-Val tRNA gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12325 SH03_RS12330 SH03_12335 SH03_RS12330 2490271 2490576 + monooxygenase gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12330 SH03_RS12335 SH03_12340 SH03_RS12335 2490702 2492306 + oxidoreductase gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12335 SH03_RS12340 SH03_12345 SH03_RS12340 2492318 2493130 - FNR%2C Nar%2C NarP-regulated protein%3B subunit of YdhYVWXUT oxidoreductase complex gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12340 SH03_RS12345 SH03_12350 SH03_RS12345 2493134 2493919 - protein PhsC gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12345 SH03_RS12350 SH03_12355 SH03_RS12350 2493916 2494584 - 4Fe-4S ferredoxin gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12350 SH03_RS12355 SH03_12360 SH03_RS12355 2494648 2495286 - hypothetical protein gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12355 SH03_RS12360 SH03_12365 SH03_RS12360 2495299 2497401 - oxidoreductase subunit gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12360 SH03_RS12365 SH03_12370 SH03_RS12365 2497422 2498048 - 4Fe-4S ferredoxin gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12365 SH03_RS12370 SH03_12375 SH03_RS12370 2498503 2498712 - hypothetical protein gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12370 SH03_RS12375 SH03_12380 SH03_RS12375 2499269 2500681 + pyruvate kinase I catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12375 SH03_RS12380 SH03_12385 SH03_RS12380 2500992 2501228 + murein lipoprotein major outer membrane lipoprotein%3B interacts with peptidoglycan to maintain the integrity of the cell envelope gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12380 SH03_RS12385 SH03_12390 SH03_RS12385 2501292 2502296 - transpeptidase catalyzes the formation of a meso-diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link in peptidoglycan synthesis gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12385 SH03_RS12390 SH03_12395 SH03_RS12390 2502445 2502861 - cysteine desulfuration protein SufE Acts with SufS to catalyze the formation of L-alanine from L-cysteine gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12390 SH03_RS12395 SH03_12400 SH03_RS12395 2502874 2504094 - cysteine desulfurase gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12395 SH03_RS12400 SH03_12405 SH03_RS12400 2504091 2505362 - Fe-S cluster assembly protein SufD with SufBC activates cysteine desulfurase SufS gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12400 SH03_RS12405 SH03_12410 sufC sufC 2505337 2506083 - Fe-S cluster assembly ATPase SufC part of SUF system involved in inserting iron-sulfur clusters into proteins%3B in Escherichia coli this protein forms a complex with SufBD%3B the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12405 SH03_RS12410 SH03_12415 SH03_RS12410 2506093 2507580 - FeS cluster assembly protein SufB with SufCD activates cysteine desulfurase SufS gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12410 SH03_RS12415 SH03_12420 sufA sufA 2507589 2507957 - protein SufA functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]%3B [4Fe-4S]) are assembled%3B forms a homodimer%3B similar to IscA protein gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12415 SH03_RS12420 SH03_12425 SH03_RS12420 2508505 2508693 - hypothetical protein gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12420 SH03_RS12425 SH03_12430 SH03_RS12425 2508793 2509203 - 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase required for efficient enterobactin production gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12425 SH03_RS12430 SH03_12435 SH03_RS12430 2509200 2512256 - FAD-linked oxidoreductase gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12430 SH03_RS12435 SH03_12440 SH03_RS12435 2512645 2513757 + hypothetical protein YdiK%3B inner membrane protein%3B ydiK promoter presents a PurR sequence%2C suggesting that its expression is purine-regulated%3B unknown function gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12435 SH03_RS12440 SH03_12445 SH03_RS12440 2514186 2514542 + HTH domain DNA-binding protein gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12440 SH03_RS12445 SH03_12450 SH03_RS12445 2514642 2515856 + transporter gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12445 SH03_RS12450 SH03_12455 SH03_RS12450 2516083 2517348 + transporter gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12450 SH03_RS12455 SH03_12460 SH03_RS12455 2517360 2518226 + quinate/shikimate dehydrogenase YdiB%3B quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12455 SH03_RS12460 SH03_12465 SH03_RS12460 2518257 2519015 + 3-dehydroquinate dehydratase gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12460 SH03_RS12465 SH03_12470 SH03_RS12465 2519158 2520753 + acetate CoA-transferase YdiF gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12465 SH03_RS12470 SH03_12475 SH03_RS12470 2520767 2521918 + acyl-CoA dehydrogenase may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12470 SH03_RS12475 SH03_12480 SH03_RS12475 2521961 2522872 - transcriptional regulator gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12475 SH03_RS12480 SH03_12485 SH03_RS12480 2522975 2523151 - hypothetical protein gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12480 SH03_RS12485 SH03_12490 SH03_RS12485 2523188 2523952 + electron transfer flavoprotein subunit gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12485 SH03_RS12490 SH03_12495 fixB fixB 2523972 2524910 + electron transfer flavoprotein%2C FAD-binding subunit involved in electron transfer during carnitine metabolism gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12490 SH03_RS12495 SH03_12500 SH03_RS12495 2524966 2526255 + electron transfer flavoprotein-quinone oxidoreductase FAD/NAD(P)-binding domain%3B possibly part of an electron transfer system required for anaerobic carnitine reduction gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12495 SH03_RS12500 SH03_12505 SH03_RS12500 2526252 2526545 + ferredoxin-like protein YdiT gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12500 SH03_RS12505 SH03_12510 SH03_RS12505 2526602 2528248 + short-chain-fatty-acid--CoA ligase acts in anaerobic beta-oxidation of fatty acids%3B possible ligase/synthase involved in anaerobic growth on fatty acids gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12505 SH03_RS12510 SH03_12515 SH03_RS12510 2528305 2530683 - phosphoenolpyruvate synthase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12510 SH03_RS12515 SH03_12520 SH03_RS12515 2530737 2530904 - hypothetical protein gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12515 SH03_RS12520 SH03_12525 SH03_RS12520 2531016 2531849 + phosphoenolpyruvate synthase regulatory protein gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12520 SH03_RS12525 SH03_12530 SH03_RS12525 2532006 2533052 + phospho-2-dehydro-3-deoxyheptonate aldolase Trp-sensitive gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12525 SH03_RS12530 SH03_12535 SH03_RS12530 2533184 2533375 + hemin uptake protein HemP homolog gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12530 SH03_RS12535 SH03_12540 SH03_RS12535 2533379 2534815 - hypothetical protein gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12535 SH03_RS12540 SH03_12545 SH03_RS12540 2534878 2535591 - anti-FlhD4C2 factor%2C inactive EAL family phosphodiesterase gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12540 SH03_RS12545 SH03_12550 SH03_RS12545 2535838 2536302 - endopeptidase gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12545 SH03_RS12550 SH03_RS12550 SH03_RS12550 2536380 2537128 - vitamin B12-transporter ATPase ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12550 SH03_RS12555 SH03_12560 btuE btuE 2537128 2537679 - vitamin B12 transport periplasmic protein BtuE similar to glutathione peroxidase%3B member of the btuCED operon which is required for vitamin B12 transport across the inner membrane gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12555 SH03_RS12560 SH03_12565 SH03_RS12560 2537742 2538722 - vitamin B12 import system permease BtuC with BtuD and BtuF transports vitamin B12 into the cell gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12560 SH03_RS12565 SH03_12570 ihfA ihfA 2538823 2539122 - integration host factor subunit alpha This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12565 SH03_RS12570 SH03_12575 pheT pheT 2539127 2541514 - phenylalanine--tRNA ligase subunit beta catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a tetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 2 subfamily gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12570 SH03_RS12575 SH03_12580 SH03_RS12575 2541529 2542512 - phenylalanine--tRNA ligase subunit alpha gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12575 SH03_RS12580 SH03_12585 SH03_RS12580 2542626 2542721 - hypothetical protein gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12580 SH03_RS12585 SH03_12590 rplT rplT 2542963 2543319 - 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12585 SH03_RS12590 SH03_12595 SH03_RS12590 2543372 2543569 - 50S ribosomal protein L35 gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12590 SH03_RS12595 SH03_12600 SH03_RS12595 2543666 2544208 - translation initiation factor IF-3 gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12595 SH03_RS12600 SH03_12605 thrS thrS 2544212 2546140 - threonine--tRNA ligase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12600 SH03_RS12605 SH03_RS12605 SH03_RS12605 2546664 2548563 + ankyrin gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12605 SH03_RS12610 SH03_12615 SH03_RS12610 2548735 2548842 + hypothetical protein gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12610 SH03_RS12615 SH03_12620 SH03_RS12615 2548895 2549653 - membrane protein gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12615 SH03_RS12620 SH03_12625 SH03_RS12620 2549940 2550869 + ATP-dependent 6-phosphofructokinase gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12620 SH03_RS12625 SH03_12630 SH03_RS12625 2550970 2551260 + hypothetical protein gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12625 SH03_RS12630 SH03_12635 SH03_RS12630 2551366 2552226 + fructosamine kinase gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12630 SH03_RS12635 SH03_12640 SH03_RS12635 2552267 2552803 - hypothetical protein gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12635 SH03_RS12640 SH03_12645 SH03_RS12640 2552950 2553618 + 2-deoxyglucose-6-phosphate phosphatase YniC%3B catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate%2C mannose 6-phosphate and p-nitrophenyl phosphate gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12640 SH03_RS12645 SH03_12650 SH03_RS12645 2553781 2554371 + hypothetical protein gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12645 SH03_RS12650 SH03_12655 SH03_RS12650 2554504 2555895 + transporter gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12650 SH03_RS12655 SH03_12660 SH03_RS12655 2555899 2556702 - hypothetical protein gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12655 SH03_RS12660 SH03_12665 SH03_RS12660 2556991 2557233 - cell division activator CedA gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12660 SH03_RS12665 SH03_12670 katE katE 2557437 2559698 + catalase HPII Catalase HPII%3B monofunctional catalase that decomposes hydrogen peroxide into water and oxygen%3B serves to protect cells from the toxic effects of hydrogen peroxide gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12665 SH03_RS12670 SH03_12675 SH03_RS12670 2559956 2560705 - chitooligosaccharide deacetylase ChbG gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12670 SH03_RS12675 SH03_12680 SH03_RS12675 2560718 2562070 - 6-phospho-beta-glucosidase catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12675 SH03_RS12680 SH03_12685 SH03_RS12680 2562175 2563014 - transcriptional regulator represses the celABCDF-ydjC operon involved in carbon uptake gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12680 SH03_RS12685 SH03_12690 SH03_RS12685 2563025 2563375 - N%2CN'-diacetylchitobiose-specific phosphotransferase enzyme IIA component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12685 SH03_RS12690 SH03_12695 SH03_RS12690 2563426 2564784 - N%2CN'-diacetylchitobiose permease IIC component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved in N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12690 SH03_RS12695 SH03_12700 SH03_RS12695 2564869 2565189 - N%2CN'-diacetylchitobiose-specific phosphotransferase enzyme IIB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved in N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12695 SH03_RS12700 SH03_12705 SH03_RS12700 2565488 2565826 - osmotically-inducible lipoprotein E osmotically-inducible lipoprotein E%3B activator of ntr-like gene protein gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12700 SH03_RS12705 SH03_12710 nadE nadE 2566028 2566855 + nH(3)-dependent NAD+ synthetase catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP%3B ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one%3B forms homodimers gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12705 SH03_RS12710 SH03_RS12710 SH03_RS12710 2566824 2567015 - hypothetical protein gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12710 SH03_RS12715 SH03_12720 SH03_RS12715 2567085 2567972 + excinuclease cho 3' incision activity%3B acts with UvrC gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12715 SH03_RS12720 SH03_12725 SH03_RS12720 2567932 2568507 - protein Ves gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12720 SH03_RS12725 SH03_12730 SH03_RS12725 2568710 2569195 - spheroplast protein Y periplasmic protein induced by stress response via Cpx and BaeSR system%3B similar to CpxP gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12725 SH03_RS12730 SH03_12735 SH03_RS12730 2569525 2570493 - succinylglutamate desuccinylase catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12730 SH03_RS12735 SH03_12740 SH03_RS12735 2570486 2571829 - N-succinylarginine dihydrolase catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine%2C ammonia and carbon dioxide in arginine degradation gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12735 SH03_RS12740 SH03_12745 astD astD 2571826 2573304 - N-succinylglutamate 5-semialdehyde dehydrogenase a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity%3B converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12740 SH03_RS12745 SH03_12750 SH03_RS12745 2573301 2574335 - arginine N-succinyltransferase gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12745 SH03_RS12750 SH03_12755 SH03_RS12750 2574332 2575552 - succinylornithine aminotransferase catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate%3B also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12750 SH03_RS12755 SH03_12760 SH03_RS12755 2575998 2576804 + exodeoxyribonuclease III gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12755 SH03_RS12760 SH03_12765 SH03_RS12760 2576971 2577681 + TVP38/TMEM64 family membrane protein YdjX gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12760 SH03_RS12765 SH03_12770 SH03_RS12765 2577686 2578363 + ferrodoxin-like lipoprotein gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12765 SH03_RS12770 SH03_12775 SH03_RS12770 2578378 2579085 + hypothetical protein gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12770 SH03_RS12775 SH03_12780 SH03_RS12775 2579085 2579633 + carboxymuconolactone decarboxylase gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12775 SH03_RS12780 SH03_12785 SH03_RS12780 2579643 2580809 + hypothetical protein gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12780 SH03_RS12785 SH03_12790 SH03_RS12785 2580782 2582317 + ABC transporter permease gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12785 SH03_RS12790 SH03_12795 SH03_RS12790 2582317 2582970 + ABC transporter ATPase gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12790 SH03_RS12795 SH03_12800 SH03_RS12795 2583037 2584344 + thiosulfate sulfurtransferase YnjE gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12795 SH03_RS12800 SH03_12805 SH03_RS12800 2584353 2584973 - hypothetical protein gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12800 SH03_RS12805 SH03_12810 SH03_RS12805 2585060 2585467 + CTP pyrophosphohydrolase gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12805 SH03_RS12810 SH03_12815 SH03_RS12810 2585433 2585705 - DUF1496 domain-containing protein gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12810 SH03_RS12815 SH03_12820 SH03_RS12815 2585941 2587284 + NADP-specific glutamate dehydrogenase converts 2-oxoglutarate to glutamate%3B in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction%3B uses NADPH%3B forms a homohexamer gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12815 SH03_RS12820 SH03_12825 SH03_RS12820 2587401 2588441 - hypothetical protein gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12820 SH03_RS12825 SH03_12830 SH03_RS12825 2588569 2590530 - DNA topoisomerase 3 decatenates replicating daughter chromosomes gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12825 SH03_RS12830 SH03_12835 SH03_RS12830 2590535 2591578 - selenophosphate synthase catalyzes the formation of selenophosphate from selenide and ATP gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12830 SH03_RS12835 SH03_12840 SH03_RS12835 2591520 2591669 - hypothetical protein gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12835 SH03_RS12840 SH03_12845 SH03_RS12840 2591695 2592246 - oxidoreductase gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12840 SH03_RS12845 SH03_12850 SH03_RS12845 2592300 2592464 + hypothetical protein gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12845 SH03_RS12850 SH03_12855 SH03_RS12850 2592407 2594263 + protease 4 SppA%3B catalyzes the degradation of cleaved signal peptides%3B essential to maintain secretion of mature proteins across the membrane gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12850 SH03_RS12855 SH03_12860 ansA ansA 2594430 2595446 + L-asparaginase 1 converts asparagine to aspartate and ammonia gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12855 SH03_RS12860 SH03_12865 SH03_RS12860 2595457 2596098 + pyrazinamidase/nicotinamidase catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12860 SH03_RS12865 SH03_12870 SH03_RS12865 2596191 2597549 - metabolite transporter gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12865 SH03_RS12870 SH03_12875 SH03_RS12870 2597666 2598424 - DeoR family transcriptional regulator gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12870 SH03_RS12875 SH03_12880 SH03_RS12875 2598561 2599541 - oxidoreductase gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12875 SH03_RS12880 SH03_12885 SH03_RS12880 2599551 2600498 - kinase gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12880 SH03_RS12885 SH03_12890 SH03_RS12885 2600503 2601339 - hypothetical protein gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12885 SH03_RS12890 SH03_12895 SH03_RS12890 2601360 2602403 - Zn-dependent NAD(P)-binding oxidoreductase gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12890 SH03_RS12895 SH03_12900 SH03_RS12895 2602420 2603799 - MFS sugar transporter membrane protein gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12895 SH03_RS12900 SH03_12905 SH03_RS12900 2603826 2604902 - Zn-dependent NAD(P)-binding oxidoreductase gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12900 SH03_RS12905 SH03_12910 SH03_RS12905 2605272 2605544 - DUF1315 domain-containing protein gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12905 SH03_RS12910 SH03_12915 SH03_RS12910 2605586 2605999 - peptide methionine sulfoxide reductase MsrB gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12910 SH03_RS12915 SH03_12920 SH03_RS12915 2606341 2607336 + glyceraldehyde-3-phosphate dehydrogenase gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12915 SH03_RS12920 SH03_12925 SH03_RS12920 2607420 2608304 + D-hexose-6-phosphate epimerase-like protein gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12920 SH03_RS12925 SH03_12930 SH03_RS12925 2608352 2609206 - aldo-keto reductase gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12925 SH03_RS12930 SH03_12935 SH03_RS12930 2609296 2610042 - MltA-interacting protein scaffolding protein for the murein polymerase MrcB and the lytic transglycosylase MltA gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12930 SH03_RS12935 SH03_12940 SH03_RS12935 2610478 2612412 + protein kinase endogenous substrate unidentified%3B autokinase gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12935 SH03_RS12940 SH03_12945 SH03_RS12940 2612525 2613808 + hypothetical protein gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12940 SH03_RS12945 SH03_12950 SH03_RS12945 2614096 2615430 + membrane protein gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12945 SH03_RS12950 SH03_12955 SH03_RS12950 2615611 2617101 + diguanylate cyclase gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12950 SH03_RS12955 SH03_12960 SH03_RS12955 2617144 2617647 + aminoacyl-tRNA editing domain protein gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12955 SH03_RS12960 SH03_12965 SH03_RS12960 2617648 2617800 - hypothetical protein gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12960 SH03_RS12965 SH03_12970 SH03_RS12965 2617922 2618368 + membrane protein gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12965 SH03_RS12970 SH03_12975 SH03_RS12970 2618325 2619146 - transcriptional regulator gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12970 SH03_RS12975 SH03_12980 SH03_RS12975 2619243 2620424 + transporter gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12975 SH03_RS12980 SH03_12985 SH03_RS12980 2620479 2620826 + DUF488 domain-containing protein gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12980 SH03_RS12985 SH03_12990 SH03_RS12985 2620848 2621102 - DUF333 domain-containing protein gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12985 SH03_RS12990 SH03_12995 SH03_RS12990 2621285 2622310 + diguanylate cyclase gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12990 SH03_RS12995 SH03_13000 SH03_RS12995 2622343 2622441 + hypothetical protein gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS12995 SH03_RS13000 SH03_13005 SH03_RS13000 2622577 2622825 - membrane protein gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13000 SH03_RS13005 SH03_13010 SH03_RS13005 2622973 2623155 - hypothetical protein gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13005 SH03_RS13010 SH03_13015 SH03_RS13010 2623159 2623518 - hypothetical protein gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13010 SH03_RS13015 SH03_13020 SH03_RS13015 2623691 2624329 - leucine efflux protein gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13015 SH03_RS13020 SH03_13025 SH03_RS13020 2624456 2625379 - transcriptional regulator gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13020 SH03_RS13025 SH03_13030 SH03_RS13025 2625482 2626567 + malate dehydrogenase gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13025 SH03_RS13030 SH03_13035 SH03_RS13030 2626773 2628203 + betaine/carnitine/choline BCCT transporter member of the betaine%2C carnitine%2C choline transporter (BCCT) family%3B unknown function gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13030 SH03_RS13035 SH03_13040 SH03_RS13035 2628235 2629359 + ring hydroxylating dioxygenase subunit alpha gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13035 SH03_RS13040 SH03_13045 SH03_RS13040 2629415 2630380 + YeaWX dioxygenase subunit beta%2C reductase component gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13040 SH03_RS13045 SH03_13050 SH03_RS13045 2630434 2631549 - ribonuclease D gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13045 SH03_RS13050 SH03_13055 SH03_RS13050 2631631 2633349 - long-chain fatty acid--CoA ligase Activates fatty acids by binding to coenzyme A gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13050 SH03_RS13055 SH03_13060 SH03_RS13055 2633521 2634102 - Slp family lipoprotein%2C RpoE-regulated gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13055 SH03_RS13060 SH03_13065 SH03_RS13060 2634142 2634837 - tRNA threonylcarbamoyladenosine biosynthesis protein TsaB gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13060 SH03_RS13065 SH03_13070 SH03_RS13065 2634895 2636805 - ATP-dependent helicase gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13065 SH03_RS13070 SH03_13075 SH03_RS13070 2636937 2637281 + hypothetical protein gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13070 SH03_RS13075 SH03_13080 SH03_RS13075 2637703 2638002 + DUF1889 domain-containing protein gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13075 SH03_RS13080 SH03_13085 SH03_RS13080 2638122 2638301 - hypothetical protein gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13080 SH03_RS13085 SH03_13090 pabB pabB 2638375 2639736 + aminodeoxychorismate synthase component I para-aminobenzoate synthase component 1%3B catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and L-glutamine gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13085 SH03_RS13090 SH03_13095 SH03_RS13090 2639740 2640318 + CoA pyrophosphohydrolase weak 3-phosphohydroxypyruvate phosphatase gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13090 SH03_RS13095 SH03_13100 SH03_RS13095 2640502 2641866 + L-serine dehydratase 1 catalyzes the formation of pyruvate from serine gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13095 SH03_RS13100 SH03_13105 SH03_RS13100 2641997 2643595 + cyclic-di-GMP phosphodiesterase gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13100 SH03_RS13105 SH03_13110 SH03_RS13105 2643599 2645155 - hypothetical protein gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13105 SH03_RS13110 SH03_13115 SH03_RS13110 2645143 2645352 - hypothetical protein gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13110 SH03_RS13115 SH03_13120 SH03_RS13115 2645618 2646589 + PTS mannose EIIAB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13115 SH03_RS13120 SH03_13125 SH03_RS13120 2646652 2647452 + mannose permease IIC component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13120 SH03_RS13125 SH03_13130 SH03_RS13125 2647465 2648316 + mannose permease IID component hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13125 SH03_RS13130 SH03_13135 SH03_RS13130 2648371 2648829 + hypothetical protein gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13130 SH03_RS13135 SH03_13140 SH03_RS13135 2649016 2649261 + hypothetical protein gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13135 SH03_RS13140 SH03_13145 SH03_RS13140 2649258 2649824 + manganese efflux pump MntP membrane protein YebN gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13140 SH03_RS13145 SH03_13150 rrmA rrmA 2649821 2650630 - 23S rRNA (guanine(745)-N(1))-methyltransferase methylates the guanosine in position 745 of 23S rRNA%3B required for translation and cell growth gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13145 SH03_RS13150 SH03_13155 SH03_RS13150 2650796 2651005 - cold-shock protein CspC gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13150 SH03_RS13155 SH03_13160 SH03_RS13155 2651018 2651161 - DUF2527 domain-containing protein gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13155 SH03_RS13160 SH03_13165 SH03_RS13160 2651123 2651329 + hypothetical protein gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13160 SH03_RS13165 SH03_13170 SH03_RS13165 2651831 2652118 - hypothetical protein gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13165 SH03_RS13170 SH03_13175 SH03_RS13170 2652193 2652336 - PhoP family transcriptional regulator gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13170 SH03_RS13175 SH03_13180 SH03_RS13175 2652495 2652734 + hypothetical protein gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13175 SH03_RS13180 SH03_13185 SH03_RS13180 2652878 2653669 - transcriptional regulator KdgR regulates the genes involved in 2-keto-3-deoxy gluconate transport and catabolism gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13180 SH03_RS13185 SH03_13190 SH03_RS13185 2653846 2655219 + transporter gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13185 SH03_RS13190 SH03_RS13190 SH03_RS13190 2655265 2656146 - heat-shock protein HtpX metalloprotease gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13190 SH03_RS13195 SH03_13200 SH03_RS13195 2656338 2658386 - tail-specific protease Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13195 SH03_RS13200 SH03_13205 SH03_RS13200 2658406 2659104 - RNA chaperone ProQ affects solute and DNA transport through an unknown mechanism gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13200 SH03_RS13205 SH03_13210 SH03_RS13205 2659201 2659698 - methionine-R-sulfoxide reductase gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13205 SH03_RS13210 SH03_13215 SH03_RS13210 2659828 2661111 + hypothetical protein gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13210 SH03_RS13215 SH03_13220 SH03_RS13215 2661080 2663713 + MCE domain protein gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13215 SH03_RS13220 SH03_RS13220 yebU yebU 2663793 2665232 + RNA methyltransferase RsmF in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13220 SH03_RS13225 SH03_13230 SH03_RS13225 2665350 2665586 + hypothetical protein gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13225 SH03_RS13230 SH03_13235 SH03_RS13230 2665691 2665882 + hypothetical protein gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13230 SH03_RS13235 SH03_13240 SH03_RS13235 2665883 2666539 - serine/threonine-protein phosphatase 1 gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13235 SH03_RS13240 SH03_13245 SH03_RS13240 2666764 2666850 - hypothetical protein gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13240 SH03_RS13245 SH03_13250 SH03_RS13245 2666935 2667273 - hypothetical protein gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13245 SH03_RS13250 SH03_13255 SH03_RS13250 2667289 2668161 - hypothetical protein gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13250 SH03_RS13255 SH03_13260 SH03_RS13255 2668165 2668539 - hypothetical protein gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13255 SH03_RS13260 SH03_13265 SH03_RS13260 2668678 2668908 + DNA polymerase III subunit theta gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13260 SH03_RS13265 SH03_13270 SH03_RS13265 2669010 2669666 + hypothetical protein gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13265 SH03_RS13270 SH03_13275 SH03_RS13270 2669690 2670352 + exodeoxyribonuclease 10 3'-5' exonuclease activity on single or double-strand DNA gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13270 SH03_RS13275 SH03_13280 SH03_RS13275 2670349 2672409 - protease 2 PtrB%3B oligopeptidase that cleaves peptide bonds following arginine and lysine residues gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13275 SH03_RS13280 SH03_13285 SH03_RS13280 2672618 2673277 - hypothetical protein gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13280 SH03_RS13285 SH03_13290 SH03_RS13285 2673337 2673447 + hypothetical protein gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13285 SH03_RS13290 SH03_13295 SH03_RS13290 2673604 2673960 - hypothetical protein secreted protein%3B unknown function gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13290 SH03_RS13295 SH03_13300 SH03_RS13295 2674027 2674317 - DNA damage-inducible protein gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13295 SH03_RS13300 SH03_13305 SH03_RS13300 2674451 2675629 + phosphoribosylglycinamide formyltransferase 2 gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13300 SH03_RS13305 SH03_13310 SH03_RS13305 2675685 2676326 - KHG/KDPG aldolase catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate%3B or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13305 SH03_RS13310 SH03_13315 SH03_RS13310 2676363 2678174 - phosphogluconate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13310 SH03_RS13315 SH03_13320 SH03_RS13315 2678409 2679884 - glucose-6-phosphate 1-dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13315 SH03_RS13320 SH03_13325 SH03_RS13320 2680050 2680199 - hypothetical protein gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13320 SH03_RS13325 SH03_13330 SH03_RS13325 2680222 2681091 + transcriptional regulator Represses the expression of the zwf%2C eda%2C glp and gap gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13325 SH03_RS13330 SH03_13335 SH03_RS13330 2681219 2682661 + pyruvate kinase II catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13330 SH03_RS13335 SH03_13340 SH03_RS13335 2682792 2683763 - lipid A biosynthesis myristoyltransferase Transfers myristate or laurate%2C activated on ACP%2C to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13335 SH03_RS13340 SH03_13345 SH03_RS13340 2683883 2685205 - murein DD-endopeptidase MepM gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13340 SH03_RS13345 SH03_13350 znuA znuA 2685221 2686153 - zinc uptake system protein ZnuA involved in transport of zinc(II) with ZnuA and C gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13345 SH03_RS13350 SH03_13355 znuC znuC 2686232 2686987 + Mn2+/Zn2+ABC transporter ATP-binding protein involved in transport of zinc(II) with ZnuA and C gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13350 SH03_RS13355 SH03_13360 znuB znuB 2686984 2687769 + zinc uptake system membrane protein ZnuB involved in transport of zinc(II) with ZnuA and C gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13355 SH03_RS13360 SH03_13365 SH03_RS13360 2687916 2688926 - Holliday junction DNA helicase RuvB gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13360 SH03_RS13365 SH03_13370 ruvA ruvA 2688935 2689546 - Holliday junction DNA helicase RuvA plays an essential role in ATP-dependent branch migration of the Holliday junction gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13365 SH03_RS13370 SH03_13375 SH03_RS13370 2689821 2690423 + DUF830 domain-containing protein gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13370 SH03_RS13375 SH03_13380 ruvC ruvC 2690425 2690946 - crossover junction endodeoxyribonuclease RuvC endonuclease%3B resolves Holliday structures%3B forms a complex of RuvABC%3B the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration%3B RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13375 SH03_RS13380 SH03_13385 SH03_RS13380 2690981 2691721 - transcriptional regulator gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13380 SH03_RS13385 SH03_13390 nudB nudB 2691750 2692232 - dihydroneopterin triphosphate pyrophosphatase catalyzes the formation of dihydroneopterin phosphate from dihydroneopterin triphosphate gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13385 SH03_RS13390 SH03_13395 SH03_RS13390 2692320 2694092 - aspartate--tRNA ligase gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13390 SH03_RS13395 SH03_13400 SH03_RS13395 2694402 2694968 + isochorismatase gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13395 SH03_RS13400 SH03_13405 SH03_RS13400 2694965 2695783 + hypothetical protein gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13400 SH03_RS13405 SH03_13410 SH03_RS13405 2695836 2696231 + hypothetical protein gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13405 SH03_RS13410 SH03_13415 SH03_RS13410 2696272 2697015 + tRNA (cmo5U34)-methyltransferase catalyzes the conversion of 5-methoxyuridine to uridine-5-oxyacetic acid in tRNA gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13410 SH03_RS13415 SH03_13420 SH03_RS13415 2697012 2697983 + tRNA (mo5U34)-methyltransferase catalyzes the conversion of 5-hydroxyuridine to 5-methoxyuridine in tRNA gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13415 SH03_RS13420 SH03_13425 SH03_RS13420 2698148 2700577 - Trimethylamine-N-oxide reductase 2 catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13420 SH03_RS13425 SH03_13430 SH03_RS13425 2700602 2701702 - cytochrome c-type protein TorY gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13425 SH03_RS13430 SH03_13435 SH03_RS13430 2702090 2702836 - copper homeostasis protein CutC gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13430 SH03_RS13435 SH03_13440 SH03_RS13435 2702850 2703416 - hypothetical protein gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13435 SH03_RS13440 SH03_13445 SH03_RS13440 2703632 2705365 + arginine--tRNA ligase gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13440 SH03_RS13445 SH03_13450 SH03_RS13445 2705542 2706030 + hypothetical protein gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13445 SH03_RS13450 SH03_13455 SH03_RS13450 2706150 2706542 - flagellar biosynthesis protein FlhE gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13450 SH03_RS13455 SH03_13460 SH03_RS13455 2706542 2708620 - flagellar biosynthesis protein FlhA gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13455 SH03_RS13460 SH03_13465 flhB flhB 2708613 2709761 - flagellar biosynthetic protein FlhB membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13460 SH03_RS13465 SH03_13470 SH03_RS13465 2709963 2710607 - protein phosphatase CheZ cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13465 SH03_RS13470 SH03_13475 SH03_RS13470 2710618 2711007 - chemotaxis protein CheY chemotaxis regulator that%2C when phosphorylated%2C interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13470 SH03_RS13475 SH03_13480 SH03_RS13475 2711022 2712071 - two-component system protein-glutamate methylesterase response regulator regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13475 SH03_RS13480 SH03_13485 SH03_RS13480 2712074 2712934 - chemotaxis protein methyltransferase methylates the MCP gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13480 SH03_RS13485 SH03_13490 SH03_RS13485 2712953 2714554 - methyl-accepting chemotaxis protein IV mediates taxis toward dipeptides gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13485 SH03_RS13490 SH03_13495 SH03_RS13490 2714600 2716261 - methyl-accepting chemotaxis protein II serine sensor receptor gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13490 SH03_RS13495 SH03_13500 SH03_RS13495 2716406 2716909 - chemotaxis protein CheW gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13495 SH03_RS13500 SH03_13505 SH03_RS13500 2716930 2718888 - chemotaxis protein CheA gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13500 SH03_RS13505 SH03_13510 motB motB 2718899 2719825 - motility protein B with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13505 SH03_RS13510 SH03_13515 SH03_RS13510 2719822 2720709 - motility protein A With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13510 SH03_RS13515 SH03_13520 SH03_RS13515 2720836 2721414 - flagellar transcriptional regulator FlhC With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13515 SH03_RS13520 SH03_13525 SH03_RS13520 2721417 2721767 - flagellar transcriptional regulator FlhD with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13520 SH03_RS13525 SH03_13530 SH03_RS13525 2722547 2722975 + universal stress protein C ppGpp-dependent%3B membrane-associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13525 SH03_RS13530 SH03_13535 SH03_RS13530 2722982 2724406 - alpha%2Calpha-trehalose-phosphate synthase [UDP-forming] gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13530 SH03_RS13535 SH03_13540 SH03_RS13535 2724381 2725181 - trehalose-6-phosphate phosphatase biosynthetic%3B catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate%3B expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13535 SH03_RS13540 SH03_13545 araH araH 2725348 2726334 - arabinose ABC transporter permease Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13540 SH03_RS13545 SH03_13550 araG araG 2726349 2727863 - arabinose import ATP-binding protein AraG Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13545 SH03_RS13550 SH03_13555 SH03_RS13550 2727933 2728922 - L-arabinose-binding periplasmic protein with AraGH is involved in the transport of arabinose into the cell gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13550 SH03_RS13555 SH03_13560 SH03_RS13555 2729719 2730222 + ferritin ferritin B%3B required for virulence in Salmonella%3B may be involved in repair of damaged Fe-S clusters gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13555 SH03_RS13560 SH03_13565 SH03_RS13560 2730301 2730552 - hypothetical protein gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13560 SH03_RS13565 SH03_13570 SH03_RS13565 2730664 2730810 + hypothetical protein gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13565 SH03_RS13570 SH03_13575 SH03_RS13570 2731016 2731339 + lipoprotein%2C function unknown gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13570 SH03_RS13575 SH03_13580 SH03_RS13575 2731510 2732007 + non-heme ferritin cytoplasmic iron storage protein gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13575 SH03_RS13580 SH03_13585 SH03_RS13580 2732045 2732284 - DUF2492 domain-containing protein gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13580 SH03_RS13585 SH03_13590 SH03_RS13585 2732475 2733686 + tyrosine-specific transporter tyrosine specific permease gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13585 SH03_RS13590 SH03_13595 SH03_RS13590 2733748 2734413 - hypothetical protein gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13590 SH03_RS13595 SH03_13600 SH03_RS13595 2734609 2734695 - tRNA-Leu tRNA gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13595 SH03_RS13600 SH03_13605 SH03_RS13600 2734708 2734781 - tRNA-Cys tRNA gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13600 SH03_RS13605 SH03_13610 SH03_RS13605 2734836 2734911 - tRNA-Gly tRNA gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13605 SH03_RS13610 SH03_13615 SH03_RS13610 2735063 2735611 - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13610 SH03_RS13615 SH03_13620 uvrC uvrC 2735668 2737500 - UvrABC system protein C The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13615 SH03_RS13620 SH03_13625 sirA sirA 2737497 2738153 - transcriptional regulator in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system%3B in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13620 SH03_RS13625 SH03_13630 SH03_RS13625 2738449 2738625 + 2-oxo acid dehydrogenase gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13625 SH03_RS13630 SH03_13635 SH03_RS13630 2738612 2738836 + hypothetical protein gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13630 SH03_RS13635 SH03_13640 SH03_RS13635 2738904 2739626 - regulatory protein SdiA regulates genes involved in cell division gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13635 SH03_RS13640 SH03_13645 SH03_RS13640 2739856 2740608 - ABC transporter ATPase gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13640 SH03_RS13645 SH03_13650 SH03_RS13645 2740605 2741273 - amino acid ABC transporter permease gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13645 SH03_RS13650 SH03_13655 SH03_RS13650 2741288 2742274 - D-cysteine desulfhydrase catalyzes the formation of pyruvate from D-cysteine gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13650 SH03_RS13655 SH03_13660 SH03_RS13655 2742379 2743179 - cystine-binding periplasmic protein gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13655 SH03_RS13660 SH03_13665 SH03_RS13660 2743267 2743818 - regulator of sigma S factor FliZ expression activator of the class 2 type of flagellar operons%2C essential to achieve maximal cell motility%3B activator of type 1 fimbrial gene expression%3B cell density-responsive regulator%3B FliZ in Salmonella typhimurium induces HilA%2C an activator of invasion genes necessary to achieve full virulence gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13660 SH03_RS13665 SH03_13670 fliA fliA 2743864 2744583 - RNA polymerase sigma factor FliA sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor directs late flagellar biosynthesis genes gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13665 SH03_RS13670 SH03_13675 SH03_RS13670 2744904 2746400 - flagellin structural flagella protein%3B individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella%2C termed phase 1 and phase 2%2C each specified by separate structural genes gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13670 SH03_RS13675 SH03_13680 fliD fliD 2746666 2748072 + flagellar hook-associated protein 2 involved in flagellin assembly gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13675 SH03_RS13680 SH03_13685 fliS fliS 2748097 2748507 + flagellar protein FliS flagellin specific chaperone gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13680 SH03_RS13685 SH03_13690 SH03_RS13685 2748507 2748872 + flagellar protein FliT binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway%3B acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription%3B member of the type III cytoplasmic chaperone family gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13685 SH03_RS13690 SH03_13695 SH03_RS13690 2748950 2750437 + alpha-amylase converts 1%2C4-alpha-D-glucans to maltodextrin gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13690 SH03_RS13695 SH03_13700 SH03_RS13695 2750471 2750884 - lipoprotein gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13695 SH03_RS13700 SH03_13705 SH03_RS13700 2751071 2752276 + UPF0394 family sulfur transport domain-containing inner membrane protein gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13700 SH03_RS13705 SH03_13710 SH03_RS13705 2752273 2752506 + TusA family sulfurtransferase gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13705 SH03_RS13710 SH03_13715 SH03_RS13710 2752615 2753283 + DUF159 domain-containing protein gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13710 SH03_RS13715 SH03_13720 SH03_RS13715 2753394 2753873 + GNAT family acetyltransferase gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13715 SH03_RS13720 SH03_RS13720 SH03_RS13720 2754017 2754246 - non-LEE-encoded type III secreted effector domain protein gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13720 SH03_RS13725 SH03_RS13725 SH03_RS13725 2754343 2755145 - hypothetical protein gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13725 SH03_RS13730 SH03_13735 SH03_RS13730 2755296 2755574 + hypothetical protein gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13730 SH03_RS13735 SH03_13740 fliE fliE 2755494 2755808 - flagellar hook-basal body complex protein FliE forms a junction between the M-ring and FlgB during flagella biosynthesis gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13735 SH03_RS13740 SH03_13745 fliF fliF 2756023 2757681 + flagellar M-ring protein the MS-ring anchors the flagellum to the cytoplasmic membrane%3B part of the flagellar basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13740 SH03_RS13745 SH03_13750 fliG fliG 2757674 2758669 + flagellar motor switch protein FliG One of three proteins involved in switching the direction of the flagellar rotation gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13745 SH03_RS13750 SH03_13755 fliH fliH 2758662 2759348 + flagellar assembly protein FliH binds to and inhibits the function of flagella specific ATPase FliI gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13750 SH03_RS13755 SH03_13760 fliI fliI 2759348 2760721 + flagellum-specific ATP synthase involved in type III protein export during flagellum assembly gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13755 SH03_RS13760 SH03_13765 fliJ fliJ 2760740 2761183 + flagellar FliJ protein rod/hook and filament chaperone gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13760 SH03_RS13765 SH03_13770 SH03_RS13765 2761180 2762307 + flagellar hook-length control protein gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13765 SH03_RS13770 SH03_13775 fliL fliL 2762412 2762876 + flagellar protein FliL interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13770 SH03_RS13775 SH03_13780 fliM fliM 2762881 2763885 + flagellar motor switch protein FliM with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13775 SH03_RS13780 SH03_13785 fliN fliN 2763882 2764295 + flagellar motor switch protein FliN One of three proteins involved in switching the direction of the flagellar rotation gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13780 SH03_RS13785 SH03_13790 SH03_RS13785 2764298 2764663 + flagellar protein FliO with FlhA%2C FlhB%2C FliP%2C FliQ and FliR is one of the membrane components of the flagellar export apparatus gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13785 SH03_RS13790 SH03_13795 fliP fliP 2764663 2765400 + flagellar biosynthetic protein FliP FliP%2C with proteins FliQ and FliR%2C forms the core of the central channel in the flagella export apparatus gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13790 SH03_RS13795 SH03_13800 fliQ fliQ 2765410 2765679 + flagellar biosynthetic protein FliQ with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13795 SH03_RS13800 SH03_13805 fliR fliR 2765687 2766472 + flagellar biosynthesis protein FliR FliR%2C with proteins FliP and FliQ%2C forms the core of the central channel in the flagella export apparatus gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13800 SH03_RS13805 SH03_13810 rcsA rcsA 2766762 2767385 + transcriptional regulator with RcsB is a positive regulator of capsular polysaccharide synthesis genes gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13805 SH03_RS13810 SH03_13815 SH03_RS13810 2767429 2767617 - protein DsrB gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13810 SH03_RS13815 SH03_13820 SH03_RS13815 2767780 2768007 + hypothetical protein gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13815 SH03_RS13820 SH03_13825 SH03_RS13820 2768305 2769120 + mannosyl-3-phosphoglycerate phosphatase catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13820 SH03_RS13825 SH03_13830 SH03_RS13825 2769117 2770793 - diguanylate cyclase catalyzes the formation of cyclic di-3'%2C5'-guanylate from guanosine triphosphate%3B involved in the regulation of cellulose biosynthesis gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13825 SH03_RS13830 SH03_13835 SH03_RS13830 2770982 2771164 - hypothetical protein gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13830 SH03_RS13835 SH03_13840 SH03_RS13835 2771243 2772160 - hypothetical protein gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13835 SH03_RS13840 SH03_13845 SH03_RS13840 2772333 2773253 + amino acid exporter for phenylalanine%2C threonine gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13840 SH03_RS13845 SH03_13850 SH03_RS13845 2773242 2773712 - very short patch repair protein DNA mismatch endonuclease%3B recognizes and repairs T:G mismatches gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13845 SH03_RS13850 SH03_13855 SH03_RS13850 2773693 2775111 - DNA-cytosine methyltransferase gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13850 SH03_RS13855 SH03_13860 SH03_RS13855 2775178 2775873 - hydrolase gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13855 SH03_RS13860 SH03_13865 SH03_RS13860 2775913 2776215 - permease gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13860 SH03_RS13870 SH03_RS13870 SH03_RS13870 2776845 2778037 + porin allows for ions and hydrophilic solutes to cross the outer membrane gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13870 SH03_RS13875 SH03_13880 SH03_RS13875 2778038 2778241 - hypothetical protein gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13875 SH03_RS13880 SH03_13885 SH03_RS13880 2778629 2779480 + Molecular chaperone Hsp31 and glyoxalase 3 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13880 SH03_RS13885 SH03_13890 SH03_RS13885 2779588 2780946 - two-component system sensor histidine kinase gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13885 SH03_RS13890 SH03_13895 SH03_RS13890 2780946 2781617 - two-component system response regulator induced by CusR in the presence of copper%3B YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW%3B yedVW is one of four copper regulons found in E. coli%3B part of the copper homeostasis mechanism%3B confers resistance to copper and several drugs when induced gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13890 SH03_RS13895 SH03_13900 SH03_RS13895 2781750 2782163 + 5-hydroxyisourate hydrolase catalyzes the formation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline from 5-hydroxyisourate gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13895 SH03_RS13900 SH03_13905 SH03_RS13900 2782272 2783276 + sulfoxide reductase catalytic subunit YedY in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase%3B requires inner membrane anchor protein YedZ gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13900 SH03_RS13905 SH03_13910 SH03_RS13905 2783277 2783912 + sulfoxide reductase heme-binding subunit YedZ in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY%3B sulfite oxidase activity not demonstrated%3B contains heme gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13905 SH03_RS13910 SH03_13915 SH03_RS13910 2784169 2784819 + metal-binding protein ZinT gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13910 SH03_RS13915 SH03_13920 SH03_RS13915 2785162 2785692 + cytochrome b561 homolog 1 gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13915 SH03_RS13920 SH03_13925 SH03_RS13920 2785715 2785957 + hypothetical protein gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13920 SH03_RS13925 SH03_13930 SH03_RS13925 2786262 2786351 - tRNA-Ser tRNA gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13925 SH03_RS13930 SH03_13935 SH03_RS13930 2786445 2787242 + protein MtfA Mlc anti-repressor%3B regulates ptsG by binding and inactivating Mlc gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13930 SH03_RS13935 SH03_13940 SH03_RS13935 2787343 2787418 + tRNA-Asn tRNA gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13935 SH03_RS13940 SH03_13945 SH03_RS13940 2787732 2794808 + adhesin gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13940 SH03_RS13945 SH03_RS13945 SH03_RS13945 2795070 2796122 - hypothetical protein gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13945 SH03_RS13950 SH03_13955 SH03_RS13950 2796437 2797753 + shikimate transporter gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13950 SH03_RS13955 SH03_13960 SH03_RS13955 2797855 2799309 + AMP nucleosidase Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13955 SH03_RS13960 SH03_13965 SH03_RS13960 2799652 2800368 + transcriptional regulator gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13960 SH03_RS13965 SH03_13970 SH03_RS13965 2800821 2800896 - tRNA-Asn tRNA gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13965 SH03_RS13970 SH03_13975 SH03_RS13970 2800997 2802451 - MATE family multidrug exporter gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13970 SH03_RS13975 SH03_13980 SH03_RS13975 2802645 2802720 + tRNA-Asn tRNA gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13975 SH03_RS13980 SH03_13985 cbl cbl 2802758 2803708 - transcriptional regulator LysR-type transcriptional regulator similar to CysB%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon%3B regulated by CysB%3B DNA-binding transcriptional activator for the ssuEADCB and tauABCD operons gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13980 SH03_RS13985 SH03_13990 SH03_RS13985 2803810 2804727 - nitrogen assimilation regulatory protein nac Transcriptional activator for the hut%2C put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13985 SH03_RS13990 SH03_13995 SH03_RS13990 2805054 2805129 + tRNA-Asn tRNA gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13990 SH03_RS13995 SH03_14000 SH03_RS13995 2805185 2806117 - transpeptidase catalyzes th removal of D-alanine and attachment of the murein lipoprotein to the peptidoglycan tetrapeptide chain gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS13995 SH03_RS14000 SH03_14005 cobT cobT 2806182 2807261 - nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5%2C6-dimethylbenzimidazole gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14000 SH03_RS14005 SH03_14010 cobS cobS 2807273 2808016 - adenosylcobinamide-GDP ribazoletransferase catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14005 SH03_RS14010 SH03_14015 cobU cobU 2808013 2808558 - cobalamin biosynthesis protein CobU catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14010 SH03_RS14020 SH03_14025 SH03_RS14020 2809099 2810079 - transposase gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14020 SH03_RS14025 SH03_14030 SH03_RS14025 2810222 2810386 - hypothetical protein gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14025 SH03_RS14030 SH03_14035 SH03_RS14030 2811746 2812651 - integrase gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14030 SH03_RS14035 SH03_14040 SH03_RS14035 2812609 2812974 - transposase represses IS2 gene transcription gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14035 SH03_RS14040 SH03_14045 SH03_RS14040 2813038 2813298 + TonB-dependent receptor gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14040 SH03_RS14045 SH03_14050 SH03_RS14045 2813295 2814005 + hypothetical protein gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14045 SH03_RS14050 SH03_14055 SH03_RS14050 2814333 2817452 + antigen 43 gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14050 SH03_RS14055 SH03_RS14055 SH03_RS14055 2817573 2819134 + hypothetical protein gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14055 SH03_RS14060 SH03_14065 SH03_RS14060 2819102 2819548 + UPF0758 protein YeeS gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14060 SH03_RS14065 SH03_14070 SH03_RS14065 2819611 2819832 + hypothetical protein gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14065 SH03_RS14070 SH03_14075 SH03_RS14070 2819906 2820274 + cytoskeleton bundling-enhancing protein CbeA gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14070 SH03_RS14075 SH03_14080 SH03_RS14075 2820363 2820737 + toxin CbtA gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14075 SH03_RS14080 SH03_14085 SH03_RS14080 2820734 2820928 + hypothetical protein gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14080 SH03_RS14085 SH03_14090 SH03_RS14085 2820941 2821054 + hypothetical protein gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14085 SH03_RS14090 SH03_14095 SH03_RS14090 2821543 2821725 + hypothetical protein gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14090 SH03_RS14095 SH03_14100 SH03_RS14095 2821826 2822155 - hypothetical protein gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14095 SH03_RS14100 SH03_14105 SH03_RS14100 2822327 2823385 - hypothetical protein gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14100 SH03_RS14105 SH03_14110 SH03_RS14105 2823583 2824056 - DNA gyrase inhibitor gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14105 SH03_RS14110 SH03_14115 SH03_RS14110 2824175 2825341 - D-alanyl-D-alanine carboxypeptidase removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors%3B penicillin-binding protein 6B%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14110 SH03_RS14115 SH03_14120 sbcB sbcB 2825553 2826977 + exonuclease I Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14115 SH03_RS14120 SH03_14125 SH03_RS14120 2827020 2827247 - TusA family sulfurtransferase gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14120 SH03_RS14125 SH03_14130 SH03_RS14125 2827261 2828319 - hypothetical protein gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14125 SH03_RS14130 SH03_14135 SH03_RS14130 2828498 2829856 - low-affinity putrescine importer PlaP gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14130 SH03_RS14135 SH03_14140 SH03_RS14135 2830123 2831052 - LysR family transcriptional regulator gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14135 SH03_RS14140 SH03_14145 SH03_RS14140 2831098 2831922 - hypothetical protein gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14140 SH03_RS14145 SH03_14150 SH03_RS14145 2832005 2832259 - toxin YoeB gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14145 SH03_RS14150 SH03_14155 SH03_RS14150 2832256 2832507 - antitoxin YefM Antitoxin that counteracts the effect of the YoeB toxin gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14150 SH03_RS14155 SH03_14160 hisG hisG 2832986 2833849 + ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14155 SH03_RS14160 SH03_14165 hisD hisD 2833855 2835159 + histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14160 SH03_RS14165 SH03_14170 SH03_RS14165 2835156 2836226 + histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14165 SH03_RS14170 SH03_14175 SH03_RS14170 2836226 2837293 + histidine biosynthesis bifunctional protein HisB catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14170 SH03_RS14175 SH03_14180 hisH hisH 2837293 2837883 + imidazole glycerol phosphate synthase subunit HisH with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamide ribonucleotide%2C and glutamate in histidine biosynthesis%3B the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14175 SH03_RS14180 SH03_14185 SH03_RS14180 2837883 2838620 + 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14180 SH03_RS14185 SH03_14190 SH03_RS14185 2838602 2839378 + imidazole glycerol phosphate synthase subunit HisF gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14185 SH03_RS14190 SH03_14195 SH03_RS14190 2839372 2839983 + histidine biosynthesis bifunctional protein HisIE catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14190 SH03_RS14195 SH03_14200 SH03_RS14195 2840079 2841059 - chain length determinant protein regulator of length of O-antigen component of lipopolysaccharide chains gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14195 SH03_RS14200 SH03_14205 SH03_RS14200 2841205 2842371 - UDP-glucose 6-dehydrogenase catalyzes the formation of UDP-glucuronate from UDP-glucose gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14200 SH03_RS14205 SH03_14210 SH03_RS14205 2842620 2844026 - 6-phosphogluconate dehydrogenase decarboxylating catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14205 SH03_RS14210 SH03_14215 SH03_RS14210 2844653 2845633 - transposase gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14210 SH03_RS14215 SH03_RS14215 SH03_RS14215 2845698 2846147 - rhamnosyltransferase gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14215 SH03_RS14220 SH03_14225 SH03_RS14220 2846149 2847267 - LPS biosynthesis protein gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14220 SH03_RS14225 SH03_14230 SH03_RS14225 2847252 2847842 - LPS biosynthesis protein WbbJ%3B catalyzes the transfer of the O-acetyl moiety to the O antigen%3B part of the lipopolysaccharide biosynthetic pathway gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14225 SH03_RS14230 SH03_14235 SH03_RS14230 2847823 2848815 - beta-1%2C6-galactofuranosyltransferase WbbI gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14230 SH03_RS14235 SH03_14240 SH03_RS14235 2848818 2849984 - O-antigen polymerase gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14235 SH03_RS14240 SH03_14245 SH03_RS14240 2849984 2851087 - UDP-galactopyranose mutase gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14240 SH03_RS14245 SH03_14250 SH03_RS14245 2851095 2852342 - polisoprenol-linked O-antigen transporter gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14245 SH03_RS14250 SH03_14255 SH03_RS14250 2852339 2852896 - dTDP-4-dehydrorhamnose 3%2C5-epimerase gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14250 SH03_RS14255 SH03_14260 SH03_RS14255 2852896 2853777 - glucose-1-phosphate thymidylyltransferase gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14255 SH03_RS14260 SH03_RS14260 SH03_RS14260 2853835 2854733 - dTDP-4-dehydrorhamnose reductase with dTDP-4-dehydrorhamnose 3%2C5-epimerase forms a complex known as dTDP-L-rhamnose synthetase%3B catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14260 SH03_RS14265 SH03_14270 SH03_RS14265 2854733 2855818 - dTDP-glucose 4%2C6-dehydratase gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14265 SH03_RS14270 SH03_14275 SH03_RS14270 2856191 2857084 - UTP--glucose-1-phosphate uridylyltransferase gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14270 SH03_RS14275 SH03_14280 wcaM wcaM 2857259 2858653 - colanic acid biosynthesis protein WcaM WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface%3B may be involved in the biosynthesis of colanic acid gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14275 SH03_RS14280 SH03_14285 SH03_RS14280 2858664 2859884 - colanic acid biosynthesis glycosyltransferase WcaL gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14280 SH03_RS14285 SH03_14290 SH03_RS14285 2859881 2861161 - colanic acid biosynthesis pyruvyl transferase WcaK gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14285 SH03_RS14290 SH03_14295 SH03_RS14290 2861437 2862915 - LPS biosynthesis protein gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14290 SH03_RS14295 SH03_14300 SH03_RS14295 2862917 2864311 - UDP-glucose--undecaprenyl-phosphate glucose-1-phosphate transferase WcaJ%3B glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14295 SH03_RS14300 SH03_14305 SH03_RS14300 2864366 2865736 - phosphomannomutase capsular polysaccharide biosynthesis protein%3B catalyzes the formation of D-mannose 6-phosphate from alpha-D-mannose 1-phosphate gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14300 SH03_RS14305 SH03_14310 cpsB cpsB 2865841 2867277 - mannose-1-phosphate guanylyltransferase capsular polysaccharide colanic acid biosynthesis protein%3B catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14305 SH03_RS14310 SH03_14315 SH03_RS14310 2867280 2868503 - glycosyl transferase gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14310 SH03_RS14315 SH03_14320 SH03_RS14315 2868500 2868979 - GDP-mannose mannosyl hydrolase catalyzes the formation of GDP and D-mannose from GDP-D-mannose%3B also hydrolyzes GDP-glucose gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14315 SH03_RS14320 SH03_14325 SH03_RS14320 2868982 2869947 - GDP-L-fucose synthase bifunctional GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase%3Bcatalyzes the formation of GDP-fucose from GDP-4-dehydro-6-deoxy-D-mannose gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14320 SH03_RS14325 SH03_14330 SH03_RS14325 2869950 2871071 - GDP-mannose 4%2C6-dehydratase catalyzes the formation of GDP-4-dehydro-6-deoxy-D-mannose from GDP mannose gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14325 SH03_RS14330 SH03_14335 SH03_RS14330 2871097 2871645 - colanic acid biosynthesis acetyltransferase WcaF gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14330 SH03_RS14335 SH03_14340 SH03_RS14335 2871661 2872407 - colanic acid biosynthesis glycosyltransferase WcaE gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14335 SH03_RS14340 SH03_14345 wcaD wcaD 2872418 2873635 - colanic acid polymerase essential for colanic acid biosynthesis%3B colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14340 SH03_RS14345 SH03_14350 SH03_RS14345 2873610 2874827 - colanic acid biosynthesis glycosyltransferase WcaC gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14345 SH03_RS14350 SH03_14355 SH03_RS14350 2874824 2875312 - colanic acid biosynthesis acetyltransferase WcaB acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit)%3B wcaB is induced in sessile bacteria and by osmotic shock%2C and repressed when grown in rich medium gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14350 SH03_RS14355 SH03_14360 SH03_RS14355 2875315 2876154 - glycosyl transferase gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14355 SH03_RS14360 SH03_14365 SH03_RS14360 2876247 2878409 - tyrosine-protein kinase wzc Wzc%3B catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14360 SH03_RS14365 SH03_14370 SH03_RS14365 2878412 2878855 - protein-tyrosine phosphatase Wzb shows phosphatase activity towards the autophosphorylated Wzc protein%2C which induces colanic acid biosynthesis%3B catalyzes the phosphorylation of UDP-glucose dehydrogenase%2C an enzyme involved in colanic acid biosynthesis gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14365 SH03_RS14370 SH03_14375 SH03_RS14370 2878861 2880000 - lipoprotein required for the translocation of capsular polysaccharide through the outer membrane gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14370 SH03_RS14375 SH03_14380 SH03_RS14375 2880659 2882242 + membrane protein gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14375 SH03_RS14380 SH03_14385 SH03_RS14380 2882516 2884369 - protein AsmA YegA%3B inner membrane protein involved in the assembly of outer membrane proteins (OMPs)%3B asmA-null mutants show low lipopolysaccharide (LPS) levels%2C suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity%2C resulting on altered assembly of OMPs gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14380 SH03_RS14385 SH03_14390 SH03_RS14385 2884391 2884972 - deoxycytidine triphosphate deaminase gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14385 SH03_RS14390 SH03_14395 SH03_RS14390 2885064 2885705 - uridine kinase gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14390 SH03_RS14395 SH03_14400 SH03_RS14395 2886023 2889340 + diguanylate cyclase gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14395 SH03_RS14400 SH03_14405 SH03_RS14400 2889449 2890297 - DNA-3-methyladenine glycosylase 2 inducible%2C catalyzes the hydrolysis of alkylated DNA%2C releasing 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine and 7-methyladenine gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14400 SH03_RS14405 SH03_14410 SH03_RS14405 2890311 2890418 - hypothetical protein gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14405 SH03_RS14410 SH03_14415 SH03_RS14410 2890431 2891783 + Hsp70 chaperone family protein gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14410 SH03_RS14415 SH03_14420 SH03_RS14415 2891796 2893742 - protein kinase-related non-specific DNA-binding protein gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14415 SH03_RS14420 SH03_14425 SH03_RS14420 2893942 2894403 + hypothetical protein gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14420 SH03_RS14425 SH03_14430 SH03_RS14425 2894468 2895148 - hypothetical protein gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14425 SH03_RS14430 SH03_14435 SH03_RS14430 2895226 2895885 - VMA domain protein gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14430 SH03_RS14435 SH03_14440 SH03_RS14435 2896773 2898020 + multidrug resistance protein MdtA Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14435 SH03_RS14440 SH03_14445 SH03_RS14440 2898020 2901142 + multidrug resistance protein MdtB Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14440 SH03_RS14445 SH03_14450 SH03_RS14445 2901143 2904220 + multidrug resistance protein MdtC Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14445 SH03_RS14450 SH03_14455 SH03_RS14450 2904221 2905636 + citrate/iron-citrate/zinc-citrate efflux transporter gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14450 SH03_RS14455 SH03_14460 SH03_RS14455 2905633 2907036 + two-component system sensor histidine kinase gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14455 SH03_RS14460 SH03_14465 SH03_RS14460 2907033 2907755 + two-component system response regulator response regulator in two-component regulatory system with BaeS%3B regulator of RNA synthesis%2C flagellar biosynthesis%2C chemotaxis and transport gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14460 SH03_RS14465 SH03_14470 SH03_RS14465 2907946 2908278 + hypothetical protein gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14465 SH03_RS14470 SH03_14475 SH03_RS14470 2908425 2909786 + protease gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14470 SH03_RS14480 SH03_RS14480 SH03_RS14480 2910492 2910758 - hypothetical protein gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14480 SH03_RS14485 SH03_14490 SH03_RS14485 2910746 2911078 - hypothetical protein gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14485 SH03_RS14490 SH03_14495 SH03_RS14490 2911469 2912368 + phosphatidylglycerol kinase metal-dependent cytosolic protein with phosphatidylglycerol kinase activity%3B undetermined physiological role gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14490 SH03_RS14495 SH03_14500 SH03_RS14495 2912450 2912896 - DeoR family transcriptional regulator gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14495 SH03_RS14500 SH03_14505 SH03_RS14500 2912993 2913292 + transposase gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14500 SH03_RS14505 SH03_14510 SH03_RS14505 2913289 2914155 + transposase gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14505 SH03_RS14510 SH03_RS14510 SH03_RS14510 2914185 2914490 - transcriptional regulator gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14510 SH03_RS14515 SH03_14520 SH03_RS14515 2914590 2915630 - galactitol-1-phosphate 5-dehydrogenase Zn-dependent%3B NAD(P)-binding%3B catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14515 SH03_RS14520 SH03_14525 SH03_RS14520 2915678 2917033 - galactitol permease IIC component gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14520 SH03_RS14525 SH03_14530 SH03_RS14525 2917037 2917321 - galactitol-specific phosphotransferase enzyme IIB component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14525 SH03_RS14530 SH03_14535 SH03_RS14530 2917352 2917804 - galactitol-specific phosphotransferase enzyme IIA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14530 SH03_RS14535 SH03_14540 SH03_RS14535 2917814 2919076 - tagatose-1%2C6-bisphosphate aldolase part of the galacitol catabolism pathway%3B with GatY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1%2C6-bisphosphate gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14535 SH03_RS14540 SH03_14545 gatY gatY 2919105 2919959 - tagatose-1%2C6-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14540 SH03_RS14545 SH03_14550 SH03_RS14545 2920267 2921319 - fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1%2C6-bisphosphate gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14545 SH03_RS14550 SH03_14555 SH03_RS14550 2921576 2922853 + nucleoside transporter low affinity gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14550 SH03_RS14555 SH03_14560 SH03_RS14555 2922850 2923854 + ADP-ribosylglycohydrolase gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14555 SH03_RS14560 SH03_14565 SH03_RS14560 2923851 2924816 + kinase gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14560 SH03_RS14565 SH03_14570 SH03_RS14565 2924790 2925536 - transcriptional regulator gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14565 SH03_RS14570 SH03_14575 SH03_RS14570 2925588 2926406 - family 25 glycosyl hydrolase gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14570 SH03_RS14575 SH03_14580 SH03_RS14575 2926471 2927271 - hydroxymethylpyrimidine/phosphomethylpyrimidine kinase catalyzes the formation hydroxymethylpyrimidine phosphate from hydroxymethylpyrimidine and the formation of of 4-amino-2-methyl-5-diphosphomethylpyrimidine from hydroxymethylpyrimidine phosphate gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14575 SH03_RS14580 SH03_14585 SH03_RS14580 2927268 2928056 - hydroxyethylthiazole kinase gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14580 SH03_RS14585 SH03_14590 SH03_RS14585 2928279 2928551 - transcriptional regulator DNA-binding%3B binds the RcnA promotor gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14585 SH03_RS14590 SH03_14595 SH03_RS14590 2928672 2929496 + nickel/cobalt efflux system RcnA membrane protein conferring nickel and cobalt resistance gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14590 SH03_RS14595 SH03_14600 SH03_RS14595 2929715 2930053 + nickel/cobalt homeostasis protein RcnB gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14595 SH03_RS14600 SH03_14605 SH03_RS14600 2930135 2931169 - fimbrial-like adhesin protein gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14600 SH03_RS14605 SH03_14610 SH03_RS14605 2931185 2933665 - outer membrane usher protein YehB gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14605 SH03_RS14610 SH03_14615 SH03_RS14610 2933681 2934355 - fimbrial assembly chaperone protein StcB gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14610 SH03_RS14615 SH03_14620 SH03_RS14615 2934435 2934977 - fimbrial-like adhesin protein gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14615 SH03_RS14620 SH03_RS14620 SH03_RS14620 2935166 2935346 + hypothetical protein gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14620 SH03_RS14625 SH03_14630 SH03_RS14625 2935270 2935551 - DUF2574 domain-containing protein gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14625 SH03_RS14630 SH03_14635 SH03_RS14630 2935814 2936923 - protein mrp gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14630 SH03_RS14635 SH03_14640 metG metG 2937055 2939088 + methionine--tRNA ligase methionine--tRNA ligase%3B MetRS%3B adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate%3B some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not%3B four subfamilies exist based on sequence motifs and zinc content gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14635 SH03_RS14640 SH03_14645 SH03_RS14640 2939229 2940053 + molybdenum metabolism regulator gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14640 SH03_RS14645 SH03_RS14645 SH03_RS14645 2941665 2943024 + regulator gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14645 SH03_RS14650 SH03_14655 SH03_RS14650 2943034 2946666 + DUF4132 domain-containing protein gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14650 SH03_RS14655 SH03_14660 SH03_RS14655 2946727 2947044 + hypothetical protein gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14655 SH03_RS14660 SH03_14665 SH03_RS14660 2947351 2948439 + hexameric AAA+ MoxR family ATPase gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14660 SH03_RS14665 SH03_14670 SH03_RS14665 2948450 2950729 + hypothetical protein gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14665 SH03_RS14670 SH03_14675 SH03_RS14670 2950722 2951858 + VMA domain YehL ATPase stimulator gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14670 SH03_RS14675 SH03_14680 SH03_RS14675 2951855 2953699 + hypothetical protein gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14675 SH03_RS14680 SH03_14685 SH03_RS14680 2953980 2954441 + DUF1307 domain-containing protein gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14680 SH03_RS14685 SH03_14690 SH03_RS14685 2954481 2954951 - DUF1456 domain-containing protein gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14685 SH03_RS14690 SH03_14695 SH03_RS14690 2954998 2955717 - two-component system response regulator unknown function%3B when overproduced it confers drug-resistance gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14690 SH03_RS14695 SH03_14700 SH03_RS14695 2955714 2957399 - sensor histidine kinase gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14695 SH03_RS14700 SH03_14705 SH03_RS14700 2957621 2958352 + transcriptional regulator gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14700 SH03_RS14705 SH03_14710 SH03_RS14705 2958412 2958519 + membrane protein gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14705 SH03_RS14710 SH03_14715 SH03_RS14710 2958500 2959231 - ABC transporter permease gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14710 SH03_RS14715 SH03_14720 SH03_RS14715 2959236 2960162 - ABC transporter ATPase gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14715 SH03_RS14720 SH03_14725 SH03_RS14720 2960155 2961312 - ABC transporter permease gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14720 SH03_RS14725 SH03_14730 SH03_RS14725 2961319 2962236 - ABC transporter substrate-binding protein gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14725 SH03_RS14730 SH03_14735 SH03_RS14730 2962447 2964744 - periplasmic beta-glucosidase catalyzes the hydrolysis of terminal beta-D-glucosyl residues gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14730 SH03_RS14735 SH03_14740 SH03_RS14735 2964940 2966655 + lactate dehydrogenase component of the membrane-bound D-lactate oxidase%2C FAD-binding%2C NADH independent gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14735 SH03_RS14740 SH03_14745 pbpG pbpG 2966693 2967625 - D-alanyl-D-alanine endopeptidase specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi%3B Penicillin-binding protein 7 gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14740 SH03_RS14745 SH03_14750 SH03_RS14745 2967799 2968386 - hypothetical protein gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14745 SH03_RS14750 SH03_14755 SH03_RS14750 2968556 2969134 + hypothetical protein gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14750 SH03_RS14755 SH03_14760 SH03_RS14755 2969264 2970025 - oxidoreductase gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14755 SH03_RS14760 SH03_RS14760 SH03_RS14760 2970078 2971513 - multidrug transporter permease may be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14760 SH03_RS14765 SH03_14770 SH03_RS14765 2971737 2971820 + hypothetical protein gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14765 SH03_RS14770 SH03_14775 SH03_RS14770 2972193 2973140 - tRNA-dihydrouridine synthase C gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14770 SH03_RS14775 SH03_14780 SH03_RS14775 2973379 2973777 + hypothetical protein gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14775 SH03_RS14780 SH03_14785 SH03_RS14780 2973774 2974469 + hypothetical protein gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14780 SH03_RS14785 SH03_14790 SH03_RS14785 2974599 2975483 + cytidine deaminase Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14785 SH03_RS14790 SH03_14795 SH03_RS14790 2975633 2976352 + protein SanA involved in vancomycin sensitivity and other barrier functions of the cell envelope gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14790 SH03_RS14795 SH03_14800 SH03_RS14795 2976355 2976594 + DUF2542 domain-containing protein gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14795 SH03_RS14800 SH03_14805 SH03_RS14800 2976788 2978026 + NAD-dependent dihydropyrimidine dehydrogenase subunit PreT gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14800 SH03_RS14805 SH03_14810 SH03_RS14805 2978020 2979255 + NAD-dependent dihydropyrimidine dehydrogenase subunit PreA gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14805 SH03_RS14810 SH03_14815 mglC mglC 2979498 2980508 - beta-methylgalactoside transporter permease ABC transporter%3B functions in galactose transport%3B part of MglA2C2B transporter complex gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14810 SH03_RS14815 SH03_14820 SH03_RS14815 2980650 2981153 - transposase gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14815 SH03_RS14820 SH03_RS14820 SH03_RS14820 2981304 2982821 - sugar ABC transporter ATP-binding protein gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14820 SH03_RS14825 SH03_14830 SH03_RS14825 2982882 2983880 - D-galactose-binding periplasmic protein wtih MglAC is involved in the transport of beta-methylgalactoside gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14825 SH03_RS14830 SH03_14835 SH03_RS14830 2984160 2985200 - transcriptional regulator controls transcription of galETKM gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14830 SH03_RS14835 SH03_14840 SH03_RS14835 2985190 2985393 + hypothetical protein gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14835 SH03_RS14840 SH03_14845 SH03_RS14840 2985342 2986499 - DUF418 domain-containing protein gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14840 SH03_RS14845 SH03_14850 folE folE 2986516 2987184 - GTP cyclohydrolase 1 involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14845 SH03_RS14850 SH03_14855 SH03_RS14850 2987338 2987514 + hypothetical protein gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14850 SH03_RS14855 SH03_14860 SH03_RS14855 2987442 2988278 + S-formylglutathione hydrolase YeiG gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14855 SH03_RS14860 SH03_14865 SH03_RS14860 2988310 2990301 - colicin I receptor Cir%3B FeuA%3B CirA%3B receptor protein for siderophores (colicin IA%2C IB and V) and microcins (E492%2C H47%2C and M)%3B TonB-dependent%3B able to transport monomers%2C dimer%2C and linear trimers of 2%2C3-dihydorxybenzoylserine%3B outer membrane protein gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14860 SH03_RS14865 SH03_14870 SH03_RS14865 2990595 2992064 - lysine-specific permease gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14865 SH03_RS14870 SH03_14875 SH03_RS14870 2992269 2993150 - transcriptional regulator gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14870 SH03_RS14875 SH03_14880 SH03_RS14875 2993249 2994298 + hypothetical protein gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14875 SH03_RS14880 SH03_14885 SH03_RS14880 2994372 2995229 + endonuclease IV with intrinsic 3''-5'' exonuclease activity Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14880 SH03_RS14885 SH03_14890 SH03_RS14885 2995232 2996320 + kinase gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14885 SH03_RS14890 SH03_14895 SH03_RS14890 2996427 2997677 - nucleoside permease NupX gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14890 SH03_RS14895 SH03_14900 rihB rihB 2997777 2998718 - pyrimidine-specific ribonucleoside hydrolase RihB Hydrolyzes cytidine or uridine to ribose and cytosine or uracil%2C respectively gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14895 SH03_RS14900 SH03_14905 SH03_RS14900 2998848 2999546 + Crp/Fnr family transcriptional regulator activator of nucleoside metabolism gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14900 SH03_RS14905 SH03_14910 SH03_RS14905 2999617 3000867 - nucleoside transporter gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14905 SH03_RS14910 SH03_14915 SH03_RS14910 3000961 3001899 - pseudouridine-5'-phosphate glycosidase gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14910 SH03_RS14915 SH03_14920 SH03_RS14915 3001887 3002828 - pseudouridine kinase gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14915 SH03_RS14920 SH03_14925 SH03_RS14920 3003251 3004942 - PTS fructose EIIBC component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14920 SH03_RS14925 SH03_14930 fruK fruK 3004959 3005897 - 1-phosphofructokinase converts fructose-1-phosphate and ATP to fructose-1%2C6-bisphosphate and ADP%3B highly specific for fructose-1-phopshate%3B similar to PfkB%3B forms homodimers gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14925 SH03_RS14930 SH03_14935 SH03_RS14930 3005897 3007027 - multiphosphoryl transfer protein phosphoenolpyruvate (PEP)-dependent%2C sugar transporting phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIA is phosphorylated by phospho-HPr which then transfers the phosphoryl group to the IIB component gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14930 SH03_RS14935 SH03_14940 SH03_RS14935 3007395 3008576 + sugar transporter gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14935 SH03_RS14940 SH03_14945 SH03_RS14940 3008573 3008827 - hypothetical protein gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14940 SH03_RS14945 SH03_14950 SH03_RS14945 3008982 3009554 + elongation factor P-like protein Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro%2C suggesting its involvement in the formation of the first peptide bond of a protein gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14945 SH03_RS14950 SH03_14955 SH03_RS14950 3009777 3011243 + NAD-dependent D-mannonate oxidoreductase gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14950 SH03_RS14955 SH03_14960 SH03_RS14955 3011361 3012347 + GTPase gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14955 SH03_RS14960 SH03_14965 SH03_RS14960 3012386 3013099 + lipid A 1-diphosphate synthase gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14960 SH03_RS14965 SH03_14970 spr spr 3013511 3014077 + murein DD-endopeptidase MepS/Murein LD-carboxypeptidase mutational suppressor of prc thermosensitivity gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14965 SH03_RS14970 SH03_14975 SH03_RS14970 3014258 3015814 + protein Rtn involved in resistance to the phages N4 and lambda gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14970 SH03_RS14975 SH03_14980 SH03_RS14975 3015896 3017710 + microcin ABC transporter substrate-binding protein with YejBEF is involved in resistance to microcin C gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14975 SH03_RS14980 SH03_14985 SH03_RS14980 3017711 3018805 + ABC transporter permease with YejAEF is involved in resistance to microcin C gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14980 SH03_RS14985 SH03_14990 SH03_RS14985 3018805 3019830 + ABC transporter permease part of the microcin C transport system gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14985 SH03_RS14990 SH03_14995 SH03_RS14990 3019832 3021421 + microcin C ABC transporter ATPase with YejAEF is involved in resistance to microcin C gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14990 SH03_RS14995 SH03_15000 SH03_RS14995 3021425 3021769 - hypothetical protein gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS14995 SH03_RS15000 SH03_15005 SH03_RS15000 3022102 3023292 - Bcr/CflA family drug resistance efflux transporter Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15000 SH03_RS15005 SH03_15010 SH03_RS15005 3023320 3024015 - ribosomal small subunit pseudouridine synthase A catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15005 SH03_RS15010 SH03_15015 SH03_RS15010 3024164 3025924 + ATP-dependent DNA or RNA helicase gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15010 SH03_RS15015 SH03_15020 SH03_RS15015 3026049 3026333 + 50S ribosomal protein L25 gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15015 SH03_RS15020 SH03_15025 SH03_RS15020 3026472 3027479 - nucleoid-associated protein gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15020 SH03_RS15025 SH03_15030 SH03_RS15025 3027661 3027888 + hypothetical protein gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15025 SH03_RS15030 SH03_15035 SH03_RS15030 3027908 3029668 + hypothetical protein gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15030 SH03_RS15035 SH03_15040 SH03_RS15035 3029743 3029819 + tRNA-Pro tRNA gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15035 SH03_RS15040 SH03_15045 SH03_RS15040 3029922 3032432 - membrane protein gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15040 SH03_RS15045 SH03_15050 SH03_RS15045 3032597 3033577 - transposase gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15045 SH03_RS15050 SH03_15055 SH03_RS15050 3033743 3034000 - hypothetical protein gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15050 SH03_RS15055 SH03_15060 SH03_RS15055 3034032 3034679 + transcriptional regulator nitrate/nitrite response regulator NarP%3B NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems%3B represses expression of other anaerobic genes gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15055 SH03_RS15060 SH03_15065 SH03_RS15060 3034890 3035942 - cytochrome c-type biogenesis protein CcmH cytochrome c-type biogenesis protein%3B involved in the attachment of heme to cytochrome c gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15060 SH03_RS15065 SH03_15070 SH03_RS15065 3035939 3036496 - thiol:disulfide interchange protein DsbE cytochrome c-type biogenesis thioredoxin%3B involved in the reduction of disulfide bonds to allow heme bonding gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15065 SH03_RS15070 SH03_15075 SH03_RS15070 3036493 3038436 - cytochrome c-type biogenesis protein CcmF cytochrome c-type biogenesis protein%3B required for the transfer of heme to apocytochrome c gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15070 SH03_RS15075 SH03_15080 SH03_RS15075 3038433 3038912 - cytochrome c-type biogenesis protein CcmE CycJ%3B periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes%3B requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome%3B part of the cytochrome c maturation system%3B periplasmic protein anchored to the inner membrane gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15075 SH03_RS15080 SH03_15085 SH03_RS15080 3038909 3039118 - heme exporter protein D is invovled in heme transfer during cytochrome c biogenesis%3B acts to stabilize CcmC and CcmE gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15080 SH03_RS15085 SH03_15090 SH03_RS15085 3039115 3039852 - heme exporter protein C with CcmABDE is involved in the transport of protoheme IX%3B CcmC is required for heme transfer to CcmE gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15085 SH03_RS15090 SH03_15095 SH03_RS15090 3039894 3040553 - heme ABC transporter permease with CcmABCE is involved in the transport of protoheme IX%3B CcmB is required for the release of holoCcmE from CcmC gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15090 SH03_RS15095 SH03_15100 SH03_RS15095 3040553 3041170 - cytochrome C biogenesis protein CcmA gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15095 SH03_RS15100 SH03_15105 SH03_RS15100 3041189 3041791 - cytochrome c-type protein NapC with NapABDFGH functions as a nitrate reductase%3B NapC functions as an electron shuttle between NapAB and NapGH or quinone gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15100 SH03_RS15105 SH03_15110 napB napB 3041801 3042250 - periplasmic nitrate reductase electron transfer subunit small subunit of periplasmic nitrate reductase%3B receives electrons from the membrane-bound NapC and passes them to NapA gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15105 SH03_RS15110 SH03_15115 napH napH 3042247 3043110 - ferredoxin-type protein NapH part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15110 SH03_RS15115 SH03_15120 napG napG 3043097 3043792 - ferredoxin-type protein NapG part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA%3B secreted by twin arginine translocation pathway gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15115 SH03_RS15120 SH03_15125 SH03_RS15120 3043799 3046285 - periplasmic nitrate reductase periplasmic%3B catalytic subunit%3B with NapBC catalyzes the reduction of nitrate to nitrite%3B NapAB receives electrons from NapC gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15120 SH03_RS15125 SH03_15130 SH03_RS15125 3046282 3046545 - protein NapD gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15125 SH03_RS15130 SH03_15135 SH03_RS15130 3046535 3047029 - ferredoxin-type protein NapF Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA. gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15130 SH03_RS15135 SH03_15140 SH03_RS15135 3047138 3047302 + hypothetical protein gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15135 SH03_RS15140 SH03_15145 SH03_RS15140 3047437 3047925 + ecotin serine protease inhibitor%2C inhibits trypsin and other proteases gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15140 SH03_RS15145 SH03_15150 SH03_RS15145 3048640 3050286 - malate:quinone oxidoreductase gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15145 SH03_RS15150 SH03_15155 SH03_RS15150 3050504 3052147 - ABC transporter ATP-binding protein efflux pump for the antibacterial peptide microcin J25 gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15150 SH03_RS15155 SH03_15160 SH03_RS15155 3052223 3052873 - alpha-ketoglutarate-dependent dioxygenase AlkB gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15155 SH03_RS15160 SH03_15165 SH03_RS15160 3052873 3053937 - bifunctional transcriptional activator/DNA repair enzyme Ada regulates genes involved in the repair of alkylated DNA%3B repairs DNA containing 6-O-methylguanine gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15160 SH03_RS15165 SH03_15170 SH03_RS15165 3054011 3055066 - FAD--protein FMN transferase catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine%3B involved in the maintenance and/or assembly of sulfur clusters%3B periplasmic lipoporotein anchored to the inner membrane%3B part of the thiamine pyrophosphate biosynthesis pathway gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15165 SH03_RS15170 SH03_15175 SH03_RS15170 3055178 3056281 - outer membrane protein C gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15170 SH03_RS15175 SH03_RS15175 SH03_RS15175 3056540 3056632 - glutamate decarboxylase gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15175 SH03_RS15180 SH03_15185 SH03_RS15180 3056673 3056798 - hypothetical protein gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15180 SH03_RS15185 SH03_15190 SH03_RS15185 3057020 3059692 + phosphotransferase RcsD gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15185 SH03_RS15190 SH03_15195 SH03_RS15190 3059709 3060359 + transcriptional regulator two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division%3B probably phosphorylated by RcsC or RcsF gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15190 SH03_RS15195 SH03_15200 SH03_RS15195 3060559 3063408 - histidine kinase gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15195 SH03_RS15200 SH03_15205 SH03_RS15200 3063575 3065401 + PAS domain-containing two-component system sensor histidine kinase with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15200 SH03_RS15205 SH03_15210 SH03_RS15205 3065398 3066783 + acetoacetate metabolism regulatory protein AtoC DNA-binding response regulator in two-component regulatory system with ZraS%3B response regulator/sigma54 interaction protein gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15205 SH03_RS15210 SH03_15215 SH03_RS15210 3066979 3067641 + acetate CoA-transferase subunit alpha gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15210 SH03_RS15215 SH03_15220 SH03_RS15215 3067641 3068291 + acetate CoA-transferase subunit beta gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15215 SH03_RS15220 SH03_15225 SH03_RS15220 3068288 3069610 + short-chain fatty acids transporter gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15220 SH03_RS15225 SH03_15230 SH03_RS15225 3069641 3070825 + acetyl-CoA acetyltransferase Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase%2C catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15225 SH03_RS15230 SH03_15235 SH03_RS15230 3070899 3071675 - hypothetical protein gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15230 SH03_RS15235 SH03_15240 SH03_RS15235 3071680 3073329 - host defense protein gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15235 SH03_RS15240 SH03_15245 SH03_RS15240 3073330 3073815 - alpha-2-macroglobulin gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15240 SH03_RS15245 SH03_15250 SH03_RS15245 3073831 3077844 - membrane protein gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15245 SH03_RS15250 SH03_15255 SH03_RS15250 3077868 3078491 - hypothetical protein gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15250 SH03_RS15255 SH03_15260 SH03_RS15255 3078488 3080176 - hypothetical protein gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15255 SH03_RS15260 SH03_15265 SH03_RS15260 3080325 3082952 - DNA gyrase subunit A gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15260 SH03_RS15265 SH03_15270 SH03_RS15265 3083099 3083821 + ubiquinone biosynthesis O-methyltransferase Involved in ubiquinone biosynthesis gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15265 SH03_RS15270 SH03_15275 SH03_RS15270 3083949 3087701 - adhesin gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15270 SH03_RS15275 SH03_15280 SH03_RS15275 3088173 3088316 + hypothetical protein gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15275 SH03_RS15280 SH03_15285 SH03_RS15280 3088397 3090682 + ribonucleoside-diphosphate reductase 1 subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15280 SH03_RS15285 SH03_15290 SH03_RS15285 3090916 3092046 + ribonucleoside-diphosphate reductase 1 subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15285 SH03_RS15290 SH03_15295 SH03_RS15290 3092046 3092300 + ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor%2C essential for nucleotide reduction catalyzed by ribonucleotide reductases gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15290 SH03_RS15295 SH03_15300 SH03_RS15295 3092354 3093004 - protein InaA gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15295 SH03_RS15300 SH03_15305 SH03_RS15300 3093219 3093425 + hypothetical protein gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15300 SH03_RS15305 SH03_15310 glpQ glpQ 3093467 3094543 - glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols%3B periplasmic gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15305 SH03_RS15310 SH03_15315 glpT glpT 3094548 3095906 - glycerol-3-phosphate transporter catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15310 SH03_RS15315 SH03_15320 glpA glpA 3096179 3097807 + anaerobic glycerol-3-phosphate dehydrogenase subunit A anaerobic%2C catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15315 SH03_RS15320 SH03_15325 SH03_RS15320 3097797 3099056 + anaerobic glycerol-3-phosphate dehydrogenase subunit B sn-glycerol-3-phosphate dehydrogenase (anaerobic)%3B catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate%3B part of GlpABC complex%3B presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15320 SH03_RS15325 SH03_15330 glpC glpC 3099053 3100243 + anaerobic glycerol-3-phosphate dehydrogenase subunit C anaerobic%3B with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15325 SH03_RS15330 SH03_15335 SH03_RS15330 3100436 3101335 + transposase gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15330 SH03_RS15335 SH03_15340 SH03_RS15335 3101348 3101533 + hypothetical protein gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15335 SH03_RS15340 SH03_15345 SH03_RS15340 3101574 3102377 - 2-keto-3-deoxy-L-rhamnonate aldolase catalyzes the retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate to pyruvate and lactaldehyde gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15340 SH03_RS15345 SH03_15350 SH03_RS15345 3102395 3103684 - transporter gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15345 SH03_RS15350 SH03_RS15350 SH03_RS15350 3103741 3104945 - rhamnonate dehydratase catalyzes the formation of 2-keto-3-deoxy-L-rhamnonate from L-rhamnonate gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15350 SH03_RS15355 SH03_15360 SH03_RS15355 3104960 3105742 - transcriptional regulator gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15355 SH03_RS15360 SH03_15365 SH03_RS15360 3105962 3107164 - inactive PncC family protein gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15360 SH03_RS15365 SH03_15370 SH03_RS15365 3107264 3107806 - porin gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15365 SH03_RS15370 SH03_15375 SH03_RS15370 3108085 3108510 + nucleoside triphosphatase catalyzes the hydrolysis of nucleoside triphosphates gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15370 SH03_RS15375 SH03_15380 SH03_RS15375 3108549 3109151 - LPS core heptose(II)-phosphate phosphatase catalyzes the of heptose(II) of the outer membrane lipopolysaccharide core gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15375 SH03_RS15380 SH03_15385 SH03_RS15380 3109459 3110598 + UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15380 SH03_RS15385 SH03_15390 SH03_RS15385 3110602 3111570 + undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15385 SH03_RS15390 SH03_15395 SH03_RS15390 3111570 3113552 + bifunctional polymyxin resistance protein ArnA Bifunctional polymyxin resistance arnA protein%3B catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose%3B active in certain mutant strains gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15390 SH03_RS15395 SH03_15400 SH03_RS15395 3113549 3114439 + 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD catalyzes the formation of 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15395 SH03_RS15400 SH03_15405 arnT arnT 3114439 3116091 + undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15400 SH03_RS15405 SH03_15410 SH03_RS15405 3116088 3116423 + 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE with ArnE is involved in transporting 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from the cytoplasmic face to the periplasmic face of the inner membrane gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15405 SH03_RS15410 SH03_15415 SH03_RS15410 3116423 3116809 + 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF with ArnE is responsible for the transport of 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from the cytoplasm to the periplasm gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15410 SH03_RS15415 SH03_15420 SH03_RS15415 3116803 3117069 - signal transduction protein PmrD with BasR regulates genes involved in polymyxin resistance gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15415 SH03_RS15420 SH03_15425 SH03_RS15420 3117179 3118534 - 2-succinylbenzoate--CoA ligase gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15420 SH03_RS15425 SH03_15430 SH03_RS15425 3118531 3119493 - o-succinylbenzoate synthase catalyzes the dehydration of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15425 SH03_RS15430 SH03_15435 SH03_RS15430 3119493 3120350 - 1%2C4-dihydroxy-2-naphthoyl-CoA synthase catalyzes the formation of 1%2C4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15430 SH03_RS15435 SH03_15440 SH03_RS15435 3120365 3121123 - 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase catalyzes the formation of (1 R%2C6 R)-2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15435 SH03_RS15440 SH03_15445 SH03_RS15440 3121120 3122790 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase SEPHCHC synthase%3B forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15440 SH03_RS15445 SH03_15450 SH03_RS15445 3122879 3124174 - isochorismate synthase MenF gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15445 SH03_RS15450 SH03_15455 SH03_RS15450 3124253 3124558 - protein ElaB gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15450 SH03_RS15455 SH03_15460 SH03_RS15455 3124613 3125074 - protein ElaA gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15455 SH03_RS15460 SH03_15465 SH03_RS15460 3125139 3126056 + hypothetical protein RNase BN%3B member of metallo-beta-lactamase family%3B the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase%3B in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not%3B associates with two zinc ions gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15460 SH03_RS15465 SH03_15470 SH03_RS15465 3126247 3127455 + deubiquitinase ElaD%3B specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins%3B SseL in Salmonella is required for macrophage killing and virulence%2C and it is secreted by the salmonella pathogenicity island 2 type III secretion system gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15465 SH03_RS15470 SH03_15475 SH03_RS15470 3127526 3129253 - VWA domain-containing protein gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15470 SH03_RS15475 SH03_15480 SH03_RS15475 3129391 3130362 + M28A family peptidase gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15475 SH03_RS15480 SH03_15485 SH03_RS15480 3130465 3130968 + hypothetical protein gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15480 SH03_RS15485 SH03_15490 SH03_RS15485 3131241 3131957 - hypothetical protein gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15485 SH03_RS15490 SH03_15495 SH03_RS15490 3132166 3132588 + hypothetical protein gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15490 SH03_RS15495 SH03_15500 SH03_RS15495 3132647 3133495 + hypothetical protein gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15495 SH03_RS15500 SH03_15505 SH03_RS15500 3133579 3135036 - NADH-quinone oxidoreductase subunit N Catalyzes the transfer of electrons from NADH to quinone gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15500 SH03_RS15505 SH03_15510 SH03_RS15505 3135043 3136572 - NADH:ubiquinone oxidoreductase subunit M gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15505 SH03_RS15510 SH03_15515 SH03_RS15510 3136736 3138577 - NADH-quinone oxidoreductase subunit L Catalyzes the transfer of electrons from NADH to ubiquinone gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15510 SH03_RS15515 SH03_15520 SH03_RS15515 3138574 3138876 - NADH-quinone oxidoreductase subunit K gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15515 SH03_RS15520 SH03_15525 SH03_RS15520 3138873 3139427 - NADH-quinone oxidoreductase subunit J Catalyzes the transfer of electrons from NADH to quinone gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15520 SH03_RS15525 SH03_15530 SH03_RS15525 3139439 3139981 - NADH-quinone oxidoreductase subunit I gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15525 SH03_RS15530 SH03_15535 SH03_RS15530 3139996 3140973 - NADH-quinone oxidoreductase subunit H gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15530 SH03_RS15535 SH03_15540 SH03_RS15535 3140970 3143696 - NADH-quinone oxidoreductase subunit G Catalyzes the transfer of electrons from NADH to quinone gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15535 SH03_RS15540 SH03_15545 SH03_RS15540 3143749 3145086 - NADH-quinone oxidoreductase subunit F part of NADH-ubiquinone oxidoreductase complex I%3B shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B NuoF is part of the soluble NADH dehydrogenase fragment%2C which represents the electron input part of NADH dehydrogenase gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15540 SH03_RS15545 SH03_15550 SH03_RS15545 3145083 3145583 - NADH-quinone oxidoreductase subunit E Catalyzes the transfer of electrons from NADH to quinone gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15545 SH03_RS15550 SH03_15555 SH03_RS15550 3145586 3147376 - NADH-quinone oxidoreductase subunit C/D NuoCD%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B subunits NuoCD%2C E%2C F%2C and G constitute the peripheral sector of the complex%3B in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15550 SH03_RS15555 SH03_15560 SH03_RS15555 3147482 3148144 - NADH-quinone oxidoreductase subunit B gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15555 SH03_RS15560 SH03_15565 SH03_RS15560 3148160 3148603 - NADH-quinone oxidoreductase subunit A gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15560 SH03_RS15565 SH03_15570 SH03_RS15565 3149234 3150172 - transcriptional regulator involved in the regulation of genes involved in flagella synthesis%2C motility and chemotaxis gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15565 SH03_RS15570 SH03_15575 SH03_RS15570 3151092 3152309 + glutamate--pyruvate aminotransferase AlaA broad specificity%3B family IV%3B in Corynebacterium glutamicum this protein can use glutamate%2C 2-aminobutyrate%2C and aspartate as amino donors and pyruvate as the acceptor gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15570 SH03_RS15575 SH03_15580 SH03_RS15575 3152393 3152992 + 5'-deoxynucleotidase YfbR gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15575 SH03_RS15580 SH03_15585 SH03_RS15580 3153051 3154883 - transporter gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15580 SH03_RS15585 SH03_15590 SH03_RS15585 3154970 3155620 - sugar phosphatase YfbT gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15585 SH03_RS15590 SH03_15595 SH03_RS15590 3155631 3156125 - hypothetical protein gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15590 SH03_RS15595 SH03_15600 SH03_RS15595 3156208 3156663 - membrane protein gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15595 SH03_RS15600 SH03_15605 SH03_RS15600 3156732 3156863 - hypothetical protein gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15600 SH03_RS15605 SH03_15610 SH03_RS15605 3157001 3158203 + acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA%3B also known to act on propionate gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15605 SH03_RS15610 SH03_15615 SH03_RS15610 3158278 3160422 + phosphate acetyltransferase catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate%3B when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15610 SH03_RS15615 SH03_15620 SH03_RS15615 3160612 3162132 + inner membrane transporter%3B C4-dicarboxylate anaerobic carrier family protein gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15615 SH03_RS15620 SH03_15625 SH03_RS15620 3162165 3162707 - NUDIX hydrolase gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15620 SH03_RS15625 SH03_15630 SH03_RS15625 3162765 3163316 - phosphodiesterase gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15625 SH03_RS15630 SH03_15635 SH03_RS15630 3163372 3164016 - glutathione S-transferase catalyzes the formation of 2%2C4-dinitrophenyl-S-glutathione from 1-chloro-2%2C4-dinitrobenzene and glutathione gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15630 SH03_RS15635 SH03_15640 SH03_RS15635 3164152 3164799 + disulfide-bond oxidoreductase YfcG gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15635 SH03_RS15640 SH03_15645 folX folX 3164856 3165218 + D-erythro-7%2C8-dihydroneopterin triphosphate epimerase catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15640 SH03_RS15645 SH03_15650 SH03_RS15645 3165239 3166132 + epimerase gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15645 SH03_RS15650 SH03_15655 SH03_RS15650 3166180 3167070 - transposase gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15650 SH03_RS15655 SH03_15660 SH03_RS15655 3167267 3168040 - histidine transport ATP-binding protein HisP gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15655 SH03_RS15660 SH03_15665 SH03_RS15660 3168048 3168764 - histidine ABC transporter permease with HisJPQ is involved in transport of histidine%2C lysine%2C arginine and ornithine gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15660 SH03_RS15665 SH03_15670 SH03_RS15665 3168761 3169447 - histidine ABC transporter permease with HisJMP is involved in the transport of histidine/lysine/arginine/ornithine gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15665 SH03_RS15670 SH03_15675 SH03_RS15670 3169537 3170319 - histidine-binding periplasmic protein with HisPMQ is involved in the transport of histidine gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15670 SH03_RS15675 SH03_15680 SH03_RS15675 3170540 3171322 - lysine/arginine/ornithine-binding periplasmic protein with HisPMQ is involved in the transport of histidine gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15675 SH03_RS15680 SH03_15685 SH03_RS15680 3171588 3172157 - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase partner protein catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15680 SH03_RS15685 SH03_15690 SH03_RS15685 3172252 3173769 - amidophosphoribosyltransferase Catalyzes first step of the de novo purine nucleotide biosynthetic pathway gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15685 SH03_RS15690 SH03_15695 SH03_RS15690 3173806 3174294 - colicin V production protein membrane protein required for colicin V production gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15690 SH03_RS15695 SH03_15700 SH03_RS15695 3174553 3175215 - protein DedD gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15695 SH03_RS15700 SH03_15705 SH03_RS15700 3175205 3176473 - bifunctional protein FolC gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15700 SH03_RS15705 SH03_15710 SH03_RS15705 3176543 3177457 - acetyl-CoA carboxylase carboxyltransferase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15705 SH03_RS15710 SH03_15715 SH03_RS15710 3177613 3178272 - protein DedA gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15710 SH03_RS15715 SH03_15720 truA truA 3178355 3179167 - tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15715 SH03_RS15720 SH03_15725 SH03_RS15720 3179167 3180180 - USG-1 protein gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15720 SH03_RS15725 SH03_15730 SH03_RS15725 3180246 3181382 - erythronate-4-phosphate dehydrogenase catalyzes the formation of 3-hydroxy-2-oxo-4-phosphonooxybutanoate from erythronate-4-phosphate gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15725 SH03_RS15730 SH03_15735 flk flk 3181481 3182476 + flagellar regulator flk in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system%3B lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm%3B inner membrane-anchored protein gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15730 SH03_RS15735 SH03_15740 SH03_RS15735 3182473 3183651 - arabinose efflux transporter gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15735 SH03_RS15740 SH03_15745 SH03_RS15740 3183916 3185136 - 3-oxoacyl-ACP synthase I FabB%2C beta-Ketoacyl-ACP synthase I%2C KASI%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15740 SH03_RS15745 SH03_15750 mnmC mnmC 3185295 3187301 + tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC 5-methylaminomethyl-2-thiouridine-forming enzyme methyltransferase/FAD-dependent demodification enzyme gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15745 SH03_RS15750 SH03_15755 SH03_RS15750 3187422 3187700 - hypothetical protein gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15750 SH03_RS15755 SH03_15760 SH03_RS15755 3187734 3188282 - elongation factor P hydroxylase gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15755 SH03_RS15760 SH03_15765 SH03_RS15760 3188282 3189091 - membrane protein gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15760 SH03_RS15765 SH03_15770 mepA mepA 3189091 3189915 - penicillin-insensitive murein endopeptidase D-alanyl-D-alanine endopeptidase%3B functions in hydrolyzing cell wall peptidoglycan%3B similar to LAS metallopeptidases%3B forms a dimer in periplasm gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15765 SH03_RS15770 SH03_15775 SH03_RS15770 3189919 3191004 - chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15770 SH03_RS15775 SH03_15780 SH03_RS15775 3191039 3191971 - 50S ribosomal protein L3 glutamine methyltransferase involved in methylation of ribosomal protein L3 gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15775 SH03_RS15780 SH03_15785 SH03_RS15780 3192137 3192688 + hypothetical protein gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15780 SH03_RS15785 SH03_15790 SH03_RS15785 3192759 3193580 - DUF2544 domain-containing protein gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15785 SH03_RS15790 SH03_15795 SH03_RS15790 3193582 3194121 - fimbrial-like adhesin protein gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15790 SH03_RS15795 SH03_15800 SH03_RS15795 3194118 3194606 - fimbrial-like adhesin protein gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15795 SH03_RS15800 SH03_15805 SH03_RS15800 3194603 3195100 - hypothetical protein gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15800 SH03_RS15805 SH03_15810 SH03_RS15805 3195115 3195867 - fimbrial chaperone gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15805 SH03_RS15810 SH03_RS15810 SH03_RS15810 3195887 3198532 - fimbrial assembly protein gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15810 SH03_RS15815 SH03_15820 SH03_RS15815 3198614 3199177 - fimbrial-like adhesin protein gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15815 SH03_RS15820 SH03_15825 SH03_RS15820 3199858 3200343 - phosphohistidine phosphatase gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15820 SH03_RS15825 SH03_15830 fadJ fadJ 3200546 3202690 - fatty acid oxidation complex subunit alpha multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI%3B similar to FadA2B2 complex%3B involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15825 SH03_RS15830 SH03_15835 fadI fadI 3202690 3204000 - 3-ketoacyl-CoA thiolase FadI%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadJ%3B similar to FadA2B2 complex%3B functions in beta-oxidation of fatty acids during anaerobic growth gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15830 SH03_RS15835 SH03_15840 SH03_RS15835 3204181 3204465 - hypothetical protein gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15835 SH03_RS15840 SH03_15845 SH03_RS15840 3204837 3206177 + long-chain fatty acid transporter gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15840 SH03_RS15845 SH03_15850 SH03_RS15845 3206543 3207601 + hypothetical protein gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15845 SH03_RS15850 SH03_15855 SH03_RS15850 3207783 3208538 - phospholipid-binding lipoprotein involved in maintaining OM lipid asymmetry gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15850 SH03_RS15855 SH03_15860 SH03_RS15855 3208832 3209764 + hypothetical protein gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15855 SH03_RS15860 SH03_15865 SH03_RS15860 3209840 3209914 + tRNA-Arg tRNA gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15860 SH03_RS15865 SH03_15870 SH03_RS15865 3210076 3211233 + hypothetical protein gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15865 SH03_RS15870 SH03_15875 SH03_RS15870 3211386 3211748 + glucose translocase gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15870 SH03_RS15875 SH03_15880 SH03_RS15875 3211745 3212665 + bactoprenol glucosyl transferase gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15875 SH03_RS15880 SH03_15885 SH03_RS15880 3212662 3213993 + serotype-specific glucosyl transferase CPS-53 (KpLE1) prophage gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15880 SH03_RS15885 SH03_15890 SH03_RS15885 3214292 3214636 + tail assembly protein gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15885 SH03_RS15890 SH03_15895 SH03_RS15890 3214608 3215048 - hypothetical protein gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15890 SH03_RS15895 SH03_15900 SH03_RS15895 3215075 3215710 - hypothetical protein gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15895 SH03_RS15900 SH03_15905 SH03_RS15900 3215643 3215918 - hypothetical protein gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15900 SH03_RS15905 SH03_15910 SH03_RS15905 3215918 3216406 - hypothetical protein gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15905 SH03_RS15920 SH03_15925 SH03_RS15920 3217136 3217498 + hypothetical protein gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15920 SH03_RS15925 SH03_15930 SH03_RS15925 3217564 3218388 + hypothetical protein gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15925 SH03_RS15930 SH03_15935 SH03_RS15930 3218516 3219052 + hypothetical protein gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15930 SH03_RS15935 SH03_15940 SH03_RS15935 3219043 3219405 + phage protein gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15935 SH03_RS15940 SH03_15945 SH03_RS15940 3219405 3219710 + hypothetical protein gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15940 SH03_RS15945 SH03_15950 SH03_RS15945 3219842 3220042 + transcriptional regulator gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15945 SH03_RS15950 SH03_15955 SH03_RS15950 3220226 3221161 - transcriptional regulator regulates the synthesis and expression of the dsdXA operon and dadA gene gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15950 SH03_RS15955 SH03_15960 SH03_RS15955 3221379 3222716 + dsdX permease gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15955 SH03_RS15960 SH03_15965 SH03_RS15960 3222734 3224062 + d-serine dehydratase catalyzes the formation of pyruvate from serine gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15960 SH03_RS15965 SH03_15970 emrB emrB 3224170 3225708 - multidrug resistance protein EmrY multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15965 SH03_RS15970 SH03_15975 SH03_RS15970 3225708 3226871 - multidrug resistance protein EmrK with ErmA and TolC forms a multidrug efflux system gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15970 SH03_RS15975 SH03_15980 SH03_RS15975 3227287 3227901 + positive transcription regulator EvgA response regulator in two-component regulatory system with EvgS%3B phosphorylated EvgA activates ompC%2C emrKY%2C gadABC%2C hdeAB and others genes%3B involved in acid resistance%2C osmotic adaption%2C and drug resistance gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15975 SH03_RS15980 SH03_15985 SH03_RS15980 3228116 3231499 + sensor histidine kinase gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15980 SH03_RS15985 SH03_15990 SH03_RS15985 3231555 3232700 - acetyl-CoA--oxalate CoA-transferase gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15985 SH03_RS15990 SH03_15995 SH03_RS15990 3232774 3233718 - transporter member of the AEC family of auxin efflux transporters%3B unknown function gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15990 SH03_RS15995 SH03_16000 SH03_RS15995 3233788 3235482 - oxalyl-CoA decarboxylase catalyzes the formation of formyl-CoA from oxalyl-CoA gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS15995 SH03_RS16000 SH03_16005 SH03_RS16000 3235536 3236786 - formyl-CoA--oxalate CoA-transferase catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16000 SH03_RS16005 SH03_16010 SH03_RS16005 3237299 3237934 - hypothetical protein gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16005 SH03_RS16010 SH03_16015 SH03_RS16010 3238230 3238505 + lipoprotein involved in colanic acid biosynthesis gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16010 SH03_RS16015 SH03_16020 SH03_RS16015 3238490 3238627 - hypothetical protein gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16015 SH03_RS16020 SH03_16025 SH03_RS16020 3238582 3238824 - DUF2545 domain-containing protein gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16020 SH03_RS16025 SH03_16030 SH03_RS16025 3239177 3240097 + lipid A biosynthesis palmitoleoyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16025 SH03_RS16030 SH03_16035 SH03_RS16030 3240589 3241827 - glutamate--pyruvate aminotransferase AlaC gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16030 SH03_RS16035 SH03_16040 SH03_RS16035 3242203 3243900 + sensor histidine kinase gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16035 SH03_RS16040 SH03_16045 SH03_RS16040 3243915 3244649 + two-component system response regulator gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16040 SH03_RS16045 SH03_16050 SH03_RS16045 3244662 3245519 + DNA-binding protein gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16045 SH03_RS16050 SH03_16055 SH03_RS16050 3245522 3248017 - multiphosphoryl transfer protein 1 gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16050 SH03_RS16055 SH03_16060 SH03_RS16055 3248042 3249079 - aminopeptidase YpdE metalloprotein gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16055 SH03_RS16060 SH03_16065 SH03_RS16060 3249079 3250164 - aminopeptidase YpdF Xaa-Pro aminopeptidase%3B limited methionine aminopeptidase gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16060 SH03_RS16065 SH03_16070 SH03_RS16065 3250179 3251426 - Fructose-like permease IIC component 1 gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16065 SH03_RS16070 SH03_16075 SH03_RS16070 3251448 3251774 - fructose-like phosphotransferase enzyme IIB component 1 gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16070 SH03_RS16075 SH03_16080 glk glk 3251993 3252958 - glucokinase catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16075 SH03_RS16080 SH03_16085 SH03_RS16080 3253162 3254418 + ion channel protein gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16080 SH03_RS16085 SH03_16090 SH03_RS16085 3254533 3254859 + hypothetical protein gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16085 SH03_RS16090 SH03_RS16090 SH03_RS16090 3254780 3254941 + hypothetical protein gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16090 SH03_RS16095 SH03_16100 SH03_RS16095 3255000 3256238 - divalent metal cation transporter MntH gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16095 SH03_RS16100 SH03_16105 SH03_RS16100 3256574 3257776 + nucleoside permease NupC gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16100 SH03_RS16105 SH03_16110 SH03_RS16105 3257863 3258975 + transposase gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16105 SH03_RS16110 SH03_16115 SH03_RS16110 3259175 3261364 - diguanylate cyclase gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16110 SH03_RS16115 SH03_16120 SH03_RS16115 3261573 3261648 - tRNA-Ala tRNA gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16115 SH03_RS16120 SH03_16125 SH03_RS16120 3261688 3261763 - tRNA-Ala tRNA gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16120 SH03_RS16125 SH03_16130 SH03_RS16125 3261999 3262343 + DUF1323 family DNA-binding protein gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16125 SH03_RS16130 SH03_16135 SH03_RS16130 3262345 3262737 + DUF1323 family DNA-binding protein gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16130 SH03_RS16135 SH03_16140 gltX gltX 3262789 3264204 - glutamate--tRNA ligase catalyzes a two-step reaction%2C first charging an glutamate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16135 SH03_RS16140 SH03_16145 SH03_RS16140 3264463 3264538 + tRNA-Val tRNA gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16140 SH03_RS16145 SH03_16150 SH03_RS16145 3264583 3264658 + tRNA-Val tRNA gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16145 SH03_RS16150 SH03_16155 SH03_RS16150 3264705 3264780 + tRNA-Val tRNA gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16150 SH03_RS16155 SH03_16160 SH03_RS16155 3264785 3264860 + tRNA-Lys tRNA gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16155 SH03_RS16160 SH03_16165 SH03_RS16160 3265125 3266009 - transcriptional regulator gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16160 SH03_RS16165 SH03_16170 SH03_RS16165 3266050 3266208 - hypothetical protein gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16165 SH03_RS16170 SH03_16175 SH03_RS16170 3266261 3267517 - xanthosine permease gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16170 SH03_RS16175 SH03_16180 SH03_RS16175 3267577 3268410 - purine nucleoside phosphorylase gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16175 SH03_RS16180 SH03_16185 SH03_RS16180 3268659 3269423 + outer membrane protein gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16180 SH03_RS16185 SH03_16190 SH03_RS16185 3269462 3270388 - LysR family transcriptional regulator gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16185 SH03_RS16190 SH03_16195 SH03_RS16190 3270478 3271476 + inorganic ion transporter gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16190 SH03_RS16195 SH03_16200 SH03_RS16195 3271473 3271691 - DUF3820 domain-containing protein gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16195 SH03_RS16200 SH03_16205 ligA ligA 3271693 3273708 - DNA ligase this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16200 SH03_RS16205 SH03_16210 SH03_RS16205 3273779 3274765 - FtsZ stabilizer interacts with cell division protein FitsZ and may be required to anchor septal ring structure gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16205 SH03_RS16210 SH03_16215 SH03_RS16210 3274995 3275756 + sulfate transporter CysZ gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16210 SH03_RS16215 SH03_16220 SH03_RS16215 3275941 3276912 + cysteine synthase A gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16215 SH03_RS16220 SH03_16225 SH03_RS16220 3277296 3277553 + phosphocarrier protein HPr gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16220 SH03_RS16225 SH03_16230 SH03_RS16225 3277598 3279325 + phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16225 SH03_RS16230 SH03_16235 SH03_RS16230 3279366 3279875 + glucose-specific phosphotransferase enzyme IIA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16230 SH03_RS16235 SH03_16240 pdxK pdxK 3279918 3280769 - pyridoxine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16235 SH03_RS16240 SH03_16245 SH03_RS16240 3280874 3281248 + hypothetical protein gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16240 SH03_RS16245 SH03_16250 SH03_RS16245 3281281 3282015 + WGR domain protein gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16245 SH03_RS16250 SH03_16255 cysM cysM 3282204 3283115 - cysteine synthase B catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16250 SH03_RS16255 SH03_16260 SH03_RS16255 3283249 3284346 - sulfate/thiosulfate import ATP-binding protein CysA gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16255 SH03_RS16260 SH03_16265 cysW cysW 3284336 3285211 - sulfate ABC transporter permease Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16260 SH03_RS16265 SH03_16270 SH03_RS16265 3285211 3286044 - sulfate ABC transporter permease gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16265 SH03_RS16270 SH03_16275 SH03_RS16270 3286044 3287060 - thiosulfate-binding protein gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16270 SH03_RS16275 SH03_16280 SH03_RS16275 3287364 3288155 - oxidoreductase UcpA gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16275 SH03_RS16280 SH03_16285 SH03_RS16280 3288284 3289141 - transcriptional regulator repressor for murPQ%3B N-acetylmuramic acid 6-phosphate inducible gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16280 SH03_RS16285 SH03_16290 SH03_RS16285 3289305 3290201 + N-acetylmuramic acid 6-phosphate etherase catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate%3B involved in MurNAc dissimilation pathway gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16285 SH03_RS16290 SH03_16295 murP murP 3290205 3291629 + PTS N-acetylmuramic acid EIIBC component belongs to PEP-dependent PTS system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel%3B requires crr-encoded enzyme IIA-glucose component gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16290 SH03_RS16295 SH03_16300 SH03_RS16295 3291634 3292938 + penicillin-binding protein gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16295 SH03_RS16300 SH03_16305 SH03_RS16300 3293178 3294077 - deferrochelatase/peroxidase gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16300 SH03_RS16305 SH03_16310 SH03_RS16305 3294173 3294748 - RpoE-regulated lipoprotein gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16305 SH03_RS16310 SH03_16315 SH03_RS16310 3294809 3295258 - hypothetical protein gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16310 SH03_RS16315 SH03_16320 SH03_RS16315 3295245 3295670 - acetyltransferase YpeA gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16315 SH03_RS16320 SH03_16325 SH03_RS16320 3295884 3296753 + N-acetylmuramoyl-L-alanine amidase gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16320 SH03_RS16325 SH03_16330 SH03_RS16325 3296757 3297656 + coproporphyrinogen III oxidase catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16325 SH03_RS16330 SH03_16335 SH03_RS16330 3297662 3298714 - transcriptional regulator activates the transcription of the ethanolamine utilization operon gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16330 SH03_RS16335 SH03_16340 SH03_RS16335 3298760 3299260 - ethanolamine utilization protein EutK ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16335 SH03_RS16340 SH03_16345 SH03_RS16340 3299273 3299932 - ethanolamine utilization protein EutL carboxysome structural protein involved in ethanolamine utilization gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16340 SH03_RS16345 SH03_16350 SH03_RS16345 3299942 3300829 - ethanolamine ammonia-lyase light chain catalyzes the formation of acetaldehyde from ethanolamine gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16345 SH03_RS16350 SH03_16355 SH03_RS16350 3300850 3302211 - ethanolamine ammonia-lyase heavy chain with EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16350 SH03_RS16355 SH03_16360 eutA eutA 3302223 3303626 - ethanolamine utilization protein EutA ethanolamine utilization protein EutA gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16355 SH03_RS16360 SH03_16365 SH03_RS16360 3303623 3304849 - ethanolamine utilization protein EutH may be involved in the transport of ethanolamine gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16360 SH03_RS16365 SH03_16370 SH03_RS16365 3305066 3306253 - ethanolamine utilization protein EutG aldehyde reductase%3B catalyzes the conversion of acetaldehyde to ethanol gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16365 SH03_RS16370 SH03_16375 SH03_RS16370 3306243 3307079 - ethanolamine utilization protein EutJ possible chaperonin%3B may be involved in the assembly of the carboxysome gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16370 SH03_RS16375 SH03_16380 SH03_RS16375 3307090 3308493 - ethanolamine utilization protein EutE ethanolamine utilization protein%3B catalyzes the formation of acetyl-CoA from acetaldehyde gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16375 SH03_RS16380 SH03_16385 SH03_RS16380 3308505 3308792 - ethanolamine utilization protein EutN gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16380 SH03_RS16385 SH03_16390 SH03_RS16385 3308899 3309192 - ethanolamine utilization protein EutM ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16385 SH03_RS16390 SH03_16395 SH03_RS16390 3309231 3310247 - ethanolamine utilization protein EutD gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16390 SH03_RS16395 SH03_16400 SH03_RS16395 3310244 3311047 - ethanolamine utilization cobalamin adenosyltransferase catalyzes the conversion of cob(I)yrinic acid a%2Cc-diamide to adenosylcob(III)yrinic acid a%2Cc-diamide gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16395 SH03_RS16400 SH03_16405 SH03_RS16400 3311044 3311745 - ethanolamine utilization protein EutQ gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16400 SH03_RS16405 SH03_16410 SH03_RS16405 3311720 3312199 - ethanolamine utilization protein EutP gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16405 SH03_RS16410 SH03_16415 SH03_RS16410 3312212 3312547 - ethanolamine utilization protein EutS ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16410 SH03_RS16415 SH03_16420 SH03_RS16415 3312840 3315119 - NADP-dependent malic enzyme NADP-dependent%3B catalyzes the oxidative decarboxylation of malate to form pyruvate%3B decarboxylates oxaloacetate gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16415 SH03_RS16420 SH03_16425 SH03_RS16420 3315408 3316358 + transaldolase A gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16420 SH03_RS16425 SH03_16430 SH03_RS16425 3316378 3318381 + transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16425 SH03_RS16430 SH03_16435 SH03_RS16430 3318476 3319519 - DUF1176 domain-containing protein gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16430 SH03_RS16435 SH03_16440 SH03_RS16435 3319645 3320220 - GDP-mannose pyrophosphatase NudK gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16435 SH03_RS16440 SH03_16445 SH03_RS16440 3320288 3322267 - protein AegA unknown function%3B in E. coli the aegA gene is regulated by Fnr%2C NarXL%2C and NarQ (but not ArcA)%2C induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16440 SH03_RS16445 SH03_16450 SH03_RS16445 3322473 3324173 + nitrate/nitrite two-component system sensor histidine kinase gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16445 SH03_RS16450 SH03_16455 SH03_RS16450 3324337 3327450 + multidrug efflux RND transporter permease subunit gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16450 SH03_RS16455 SH03_16460 SH03_RS16455 3327537 3327716 + hypothetical protein gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16455 SH03_RS16460 SH03_16465 SH03_RS16460 3327989 3328345 + hypothetical protein gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16460 SH03_RS16465 SH03_16470 SH03_RS16465 3328349 3329476 + succinyl-diaminopimelate desuccinylase gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16465 SH03_RS16470 SH03_16475 SH03_RS16470 3329504 3329704 + membrane protein gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16470 SH03_RS16475 SH03_16480 SH03_RS16475 3329814 3330512 - esterase gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16475 SH03_RS16480 SH03_16485 SH03_RS16480 3330586 3332601 - tRNA(Met) cytidine acetyltransferase TmcA cetylates the wobble base C34 of the elongation-specific methionine tRNA gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16480 SH03_RS16485 SH03_16490 SH03_RS16485 3332616 3333479 - hypothetical protein gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16485 SH03_RS16490 SH03_16495 SH03_RS16490 3333647 3334360 - phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16490 SH03_RS16495 SH03_16500 SH03_RS16495 3334432 3334662 + hypothetical protein gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16495 SH03_RS16500 SH03_16505 SH03_RS16500 3334573 3335607 - outer membrane protein assembly factor BamC gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16500 SH03_RS16505 SH03_16510 SH03_RS16505 3335624 3336502 - 4-hydroxy-tetrahydrodipicolinate synthase gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16505 SH03_RS16510 SH03_16515 gcvR gcvR 3336648 3337220 + glycine cleavage system transcriptional regulator negative transcriptional regulator of the gcvTHP operon gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16510 SH03_RS16515 SH03_16520 bcp bcp 3337220 3337690 + peroxiredoxin bacterioferritin comigratory protein%3B thiol peroxidase%3B thioredoxin-dependent%3B hydroperoxide peroxidase%3B in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide%3B contains an active site cysteine gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16515 SH03_RS16520 SH03_16525 SH03_RS16520 3337943 3338560 + hydrogenase-4 component A gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16520 SH03_RS16525 SH03_16530 SH03_RS16525 3338560 3340578 + hydrogenase-4 component B gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16525 SH03_RS16530 SH03_16535 hycD hycD 3340589 3341536 + hydrogenase-4 component C formate hydrogenlyase subunit 4%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16530 SH03_RS16535 SH03_16540 SH03_RS16535 3341553 3342992 + hydrogenase-4 component D gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16535 SH03_RS16540 SH03_16545 hyfE hyfE 3343004 3343654 + hydrogenase-4 component E interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16540 SH03_RS16545 SH03_16550 SH03_RS16545 3343659 3345239 + hydrogenase-4 component F gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16545 SH03_RS16550 SH03_16555 SH03_RS16550 3345229 3346896 + hydrogenase-4 component G gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16550 SH03_RS16555 SH03_16560 SH03_RS16555 3346906 3347451 + hydrogenase-4 component H electron transfer protein for hydrogenase-3%3B the formate hydrogenlyase complex comprises of a formate dehydrogenase%2C unidentified electron carriers and hydrogenase-3%3B in this non-energy conserving pathway%2C molecular hydrogen and carbodioxide are released from formate gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16555 SH03_RS16560 SH03_16565 SH03_RS16560 3347448 3348206 + hydrogenase-4 component I gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16560 SH03_RS16565 SH03_16570 SH03_RS16565 3348199 3348612 + hydrogenase-4 component J gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16565 SH03_RS16570 SH03_16575 SH03_RS16570 3348642 3350654 + hydrogenase-4 transcriptional activator gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16570 SH03_RS16575 SH03_16580 SH03_RS16575 3350676 3351524 + formate transporter gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16575 SH03_RS16580 SH03_16585 SH03_RS16580 3351562 3352623 - permease gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16580 SH03_RS16585 SH03_16590 SH03_RS16585 3352836 3354299 + beta-barrel assembly-enhancing protease gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16585 SH03_RS16590 SH03_16595 SH03_RS16590 3354320 3354679 + oxidoreductase gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16590 SH03_RS16595 SH03_16600 SH03_RS16595 3354817 3355494 - DnaA regulatory inactivator Hda controls initiation of DNA replication by inhibiting re-initiation of replication%2C promotes hydrolysis of DnaA-bound ATP gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16595 SH03_RS16600 SH03_16605 SH03_RS16600 3355613 3356902 - uracil permease gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16600 SH03_RS16605 SH03_16610 upp upp 3356988 3357614 - uracil phosphoribosyltransferase Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16605 SH03_RS16610 SH03_16615 SH03_RS16610 3357939 3358976 + phosphoribosylformylglycinamidine cyclo-ligase catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16610 SH03_RS16615 SH03_16620 purN purN 3358976 3359614 + phosphoribosylglycinamide formyltransferase glycinamide ribonucleotide transformylase%3B GAR Tfase%3B catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate%3B PurN requires formyl folate for the reaction unlike PurT which uses formate gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16615 SH03_RS16620 SH03_16625 SH03_RS16620 3359786 3361852 + polyphosphate kinase gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16620 SH03_RS16625 SH03_16630 SH03_RS16625 3361857 3363398 + exopolyphosphatase gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16625 SH03_RS16630 SH03_16635 SH03_RS16630 3363437 3365680 - cyclic di-GMP phosphodiesterase YfgF gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16630 SH03_RS16635 SH03_16640 SH03_RS16635 3365862 3366014 - hypothetical protein gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16635 SH03_RS16640 SH03_16645 SH03_RS16640 3366032 3366223 + hypothetical protein gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16640 SH03_RS16645 SH03_16650 SH03_RS16645 3366537 3367052 + membrane protein gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16645 SH03_RS16650 SH03_16655 SH03_RS16650 3367068 3367607 + hypothetical protein gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16650 SH03_RS16655 SH03_16660 guaA guaA 3367700 3369277 - GMP synthase [glutamine-hydrolyzing] contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16655 SH03_RS16660 SH03_16665 SH03_RS16660 3369346 3370812 - inosine-5-monophosphate dehydrogenase gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16660 SH03_RS16665 SH03_16670 xseA xseA 3370974 3372344 + exodeoxyribonuclease 7 large subunit bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16665 SH03_RS16670 SH03_16675 SH03_RS16670 3372341 3372556 - DUF1407 domain-containing protein gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16670 SH03_RS16675 SH03_16680 SH03_RS16675 3372626 3374098 - GTPase Der gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16675 SH03_RS16680 SH03_16685 SH03_RS16680 3374216 3375394 - outer membrane protein assembly factor BamB gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16680 SH03_RS16685 SH03_16690 SH03_RS16685 3375405 3376025 - ancillary SecYEG translocon subunit gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16685 SH03_RS16690 SH03_16695 hisS hisS 3376043 3377317 - histidine--tRNA ligase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16690 SH03_RS16695 SH03_16700 SH03_RS16695 3377428 3378546 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16695 SH03_RS16700 SH03_16705 SH03_RS16700 3378573 3379586 - cytoskeleton protein RodZ gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16700 SH03_RS16705 SH03_16710 SH03_RS16705 3379871 3381025 - 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16705 SH03_RS16710 SH03_16715 SH03_RS16710 3381175 3381606 - nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16710 SH03_RS16715 SH03_16720 SH03_RS16715 3381755 3384067 - penicillin-binding protein 1C penicillin-insensitive transglycosylase/transpeptidase gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16715 SH03_RS16720 SH03_16725 SH03_RS16720 3384068 3389029 - hypothetical protein gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16720 SH03_RS16725 SH03_16730 sseA sseA 3389236 3390081 + 3-mercaptopyruvate sulfurtransferase catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16725 SH03_RS16730 SH03_16735 SH03_RS16730 3390899 3391675 - protein SseB enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16730 SH03_RS16735 SH03_16740 SH03_RS16735 3391817 3393100 - peptidase B catalyzes the removal of an N-terminal amino acid from a peptide or arylamide gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16735 SH03_RS16740 SH03_16745 SH03_RS16740 3393278 3393478 - protein IscX gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16740 SH03_RS16745 SH03_16750 SH03_RS16745 3393490 3393825 - (2Fe-2S) ferredoxin gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16745 SH03_RS16750 SH03_16755 hscA hscA 3393827 3395677 - chaperone protein HscA involved in the maturation of iron-sulfur cluster-containing proteins gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16750 SH03_RS16755 SH03_16760 hscB hscB 3395694 3396209 - co-chaperone protein HscB J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone%3B may function in biogenesis of iron-sulfur proteins gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16755 SH03_RS16760 SH03_16765 iscA iscA 3396305 3396628 - iron-binding protein forms iron-sulfur clusters of ferredoxin [2FE-2S]%3B binds iron in the presence of the thioredoxin reductase system%3B forms homodimers and tetramers%3B similar to SufA protein gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16760 SH03_RS16765 SH03_16770 SH03_RS16765 3396645 3397031 - Fe-S cluster assembly scaffold IscU gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16765 SH03_RS16770 SH03_16775 SH03_RS16770 3397059 3398273 - cysteine desulfurase IscS catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B involved in NAD biosynthesis gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16770 SH03_RS16775 SH03_16780 SH03_RS16775 3398385 3398873 - Fe-S cluster assembly transcriptional regulator IscR regulates the expression of the iscRSUA operon gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16775 SH03_RS16780 SH03_16785 SH03_RS16780 3399325 3400065 - tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ catalyzes the fromation of 2'O-methylated cytidine or 2'O-methylated uridine at position 32 in tRNA gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16780 SH03_RS16785 SH03_16790 SH03_RS16785 3400184 3400987 + inositol-1-monophosphatase gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16785 SH03_RS16790 SH03_16795 SH03_RS16790 3401132 3401986 + S9 family prolyl oligopeptidase gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16790 SH03_RS16795 SH03_16800 SH03_RS16795 3402177 3403457 + stationary phase-inducible protein CsiE gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16795 SH03_RS16800 SH03_16805 SH03_RS16800 3403449 3404588 - 3-phenylpropionic acid transporter transporter of 3-phenylpropionate across the inner membrane%3B member of the major facilitator superfamily of transporters gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16800 SH03_RS16805 SH03_16810 SH03_RS16805 3404748 3405638 - Hca operon transcriptional activator HcaR activator of 3-phenylpropionic acid catabolism gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16805 SH03_RS16810 SH03_16815 SH03_RS16810 3405774 3407135 + 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16810 SH03_RS16815 SH03_16820 SH03_RS16815 3407132 3407650 + 3-phenylpropionate/cinnamic acid dioxygenase subunit beta gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16815 SH03_RS16820 SH03_16825 SH03_RS16820 3407650 3407970 + 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16820 SH03_RS16825 SH03_16830 SH03_RS16825 3407967 3408779 + 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase Converts cis-3-(3-carboxyethyl)-3%2C5-cyclohexadiene-1%2C2-diol (PP-dihydrodiol) into 3-(2%2C3-dihydroxylphenyl)propionate gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16825 SH03_RS16830 SH03_16835 SH03_RS16830 3408789 3409991 + 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD+ reductase component gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16830 SH03_RS16835 SH03_16840 SH03_RS16835 3410088 3410510 + hypothetical protein gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16835 SH03_RS16840 SH03_16845 SH03_RS16840 3410558 3411430 - mutarotase superfamily protein%2C YphB family gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16840 SH03_RS16845 SH03_16850 SH03_RS16845 3411442 3412503 - Zn-dependent NAD(P)-binding oxidoreductase gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16845 SH03_RS16850 SH03_16855 SH03_RS16850 3412569 3413567 - ABC transporter permease gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16850 SH03_RS16855 SH03_16860 SH03_RS16855 3413592 3415103 - sugar ABC transporter ATPase gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16855 SH03_RS16860 SH03_16865 SH03_RS16860 3415126 3416109 - ABC transporter substrate-binding protein gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16860 SH03_RS16865 SH03_16870 SH03_RS16865 3416206 3419487 - DUF4380 domain-containing protein gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16865 SH03_RS16870 SH03_16875 SH03_RS16870 3419605 3420798 + transcriptional regulator gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16870 SH03_RS16875 SH03_16880 SH03_RS16875 3420996 3422249 - serine hydroxymethyltransferase gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16875 SH03_RS16880 SH03_16885 SH03_RS16880 3422577 3423767 + flavohemoprotein flavohemoprotein%3B catalyzes the formation of nitrate from nitric oxide%3B can also catalyze the reduction of dihydropteridine gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16880 SH03_RS16885 SH03_16890 SH03_RS16885 3423812 3424150 - nitrogen regulatory protein P-II 1 indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16885 SH03_RS16890 SH03_16895 SH03_RS16890 3424211 3425545 - transcriptional regulator with GlrK is part of a two-component signal transduction system regulating glmY gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16890 SH03_RS16895 SH03_16900 SH03_RS16895 3425535 3426248 - quorum-sensing regulator protein G gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16895 SH03_RS16900 SH03_16905 SH03_RS16900 3426413 3427840 - two-component system sensor histidine kinase part of the GlrKR two-component signal transduction system involved in the regulation of glmY gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16900 SH03_RS16905 SH03_16910 SH03_RS16905 3428398 3432285 - phosphoribosylformylglycinamidine synthase catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16905 SH03_RS16910 SH03_16915 SH03_RS16910 3432543 3434099 + murein transglycosylase gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16910 SH03_RS16915 SH03_16920 SH03_RS16915 3434096 3434599 - tRNA-specific adenosine deaminase gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16915 SH03_RS16920 SH03_16925 SH03_RS16920 3434657 3435292 - phosphatidylglycerophosphatase C gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16920 SH03_RS16925 SH03_16930 SH03_RS16925 3435501 3436349 + transcriptional regulator gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16925 SH03_RS16930 SH03_16935 SH03_RS16930 3436405 3436665 + 4Fe-4S binding protein gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16930 SH03_RS16935 SH03_16940 SH03_RS16935 3436859 3436939 - small toxic protein ShoB gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16935 SH03_RS16940 SH03_16945 SH03_RS16940 3436936 3437088 - hypothetical protein gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16940 SH03_RS16945 SH03_RS16945 SH03_RS16945 3437125 3437253 + glutamate decarboxylase gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16945 SH03_RS16950 SH03_16955 acpS acpS 3437360 3437740 - holo-ACP synthase Catalyzes the formation of holo-ACP%2C which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16950 SH03_RS16955 SH03_16960 SH03_RS16955 3437740 3438471 - pyridoxine 5'-phosphate synthase involved in the de novo synthesis of pyridoxine (Vitamin B6) gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16955 SH03_RS16960 SH03_16965 recO recO 3438483 3439211 - DNA repair protein RecO involved in DNA repair and RecFOR pathway recombination%3B RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16960 SH03_RS16965 SH03_16970 SH03_RS16965 3439223 3440128 - GTPase Era gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16965 SH03_RS16970 SH03_16975 rnc rnc 3440125 3440805 - ribonuclease 3 cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16970 SH03_RS16975 SH03_16980 SH03_RS16975 3441077 3442051 - signal peptidase I catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16975 SH03_RS16980 SH03_16985 SH03_RS16980 3442067 3443866 - elongation factor 4 gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16980 SH03_RS16985 SH03_16990 SH03_RS16985 3444064 3444543 - protein RseC involved in the reduction of the SoxR iron-sulfur cluster gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16985 SH03_RS16990 SH03_16995 rseB rseB 3444540 3445496 - sigma-E factor regulatory protein RseB periplasmic protein%3B interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16990 SH03_RS16995 SH03_17000 SH03_RS16995 3445496 3446146 - anti-sigma-E factor RseA gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS16995 SH03_RS17000 SH03_17005 SH03_RS17000 3446179 3446754 - ECF RNA polymerase sigma-E factor Member of the extracytoplasmic function sigma factors which are active under specific conditions%3B binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription%3B this sigma factor is involved in heat shock and oxidative stress response gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17000 SH03_RS17005 SH03_17010 SH03_RS17005 3446751 3446906 - hypothetical protein gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17005 SH03_RS17010 SH03_17015 SH03_RS17010 3447162 3448784 + L-aspartate oxidase catalyzes the formation of oxaloacetate from L-aspartate gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17010 SH03_RS17015 SH03_17020 SH03_RS17015 3448769 3449506 - tRNA1(Val) (adenine(37)-N6)-methyltransferase gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17015 SH03_RS17020 SH03_17025 SH03_RS17020 3449638 3450972 + ATP-dependent RNA helicase SrmB facilitates an early step in the assembly of the 50S subunit of the ribosome gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17020 SH03_RS17025 SH03_17030 SH03_RS17025 3450978 3451130 + hypothetical protein gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17025 SH03_RS17030 SH03_17035 SH03_RS17030 3451181 3452062 - transcriptional regulator gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17030 SH03_RS17035 SH03_17040 SH03_RS17035 3452165 3452752 + cysteine/O-acetylserine efflux protein gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17035 SH03_RS17040 SH03_17045 SH03_RS17040 3452808 3453191 - autonomous glycyl radical cofactor GrcA stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17040 SH03_RS17045 SH03_17050 SH03_RS17045 3453496 3454185 + uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17045 SH03_RS17050 SH03_17055 SH03_RS17050 3454233 3455270 - methyltransferase gene gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17050 SH03_RS17055 SH03_17060 SH03_RS17055 3455260 3455418 - hypothetical protein gene gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17055 SH03_RS17060 SH03_17065 SH03_RS17060 3455477 3455896 + thioredoxin gene gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17060 SH03_RS17065 SH03_17070 SH03_RS17065 3455965 3456663 + DTW domain-containing protein YfiP gene gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17065 SH03_RS17070 SH03_17075 SH03_RS17070 3456695 3459355 + protein lysine acetyltransferase Pka catalyzes the acetylation of lysine gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17070 SH03_RS17075 SH03_17080 pssA pssA 3459469 3460824 + CDP-diacylglycerol--serine O-phosphatidyltransferase catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine%3B bounds to the ribosome gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17075 SH03_RS17080 SH03_17085 SH03_RS17080 3460921 3461193 + lipoprotein gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17080 SH03_RS17085 SH03_17090 SH03_RS17085 3461190 3462488 - alpha-ketoglutarate permease gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17085 SH03_RS17090 SH03_RS17090 SH03_RS17090 3462604 3462804 - hypothetical protein gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17090 SH03_RS17095 SH03_17100 SH03_RS17095 3462813 3462928 - 5S ribosomal RNA rRNA gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17095 SH03_RS17100 SH03_17105 SH03_RS17100 3463006 3465935 - 23S ribosomal RNA rRNA gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17100 SH03_RS17105 SH03_17110 SH03_RS17105 3466111 3466186 - tRNA-Glu tRNA gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17105 SH03_RS17110 SH03_17115 SH03_RS17110 3466346 3467901 - 16S ribosomal RNA rRNA gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17110 SH03_RS17115 SH03_17120 SH03_RS17115 3468342 3470915 - chaperone protein ClpB gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17115 SH03_RS17120 SH03_17125 SH03_RS17120 3471045 3471776 - Laccase YfiH gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17120 SH03_RS17125 SH03_17130 rluD rluD 3471773 3472753 - ribosomal large subunit pseudouridine synthase D responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17125 SH03_RS17130 SH03_17135 SH03_RS17130 3472888 3473625 + outer membrane protein assembly factor BamD gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17130 SH03_RS17135 SH03_17140 SH03_RS17135 3473655 3473861 + hypothetical protein gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17135 SH03_RS17140 SH03_17145 SH03_RS17140 3473896 3474237 + ribosome-associated inhibitor A associated with 30S ribosomal subunit%3B interferes with translation elongation gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17140 SH03_RS17145 SH03_17150 pheA pheA 3474487 3475647 + P-protein catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17145 SH03_RS17150 SH03_17155 tyrA tyrA 3475690 3476811 - T-protein catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17150 SH03_RS17155 SH03_17160 SH03_RS17155 3476822 3477892 - phospho-2-dehydro-3-deoxyheptonate aldolase Tyr-sensitive catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C tyrosine sensitive gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17155 SH03_RS17160 SH03_17165 SH03_RS17160 3478102 3478467 + lipoprotein gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17160 SH03_RS17165 SH03_17170 SH03_RS17165 3478617 3479135 + hypothetical protein gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17165 SH03_RS17170 SH03_17175 SH03_RS17170 3479128 3480351 + diguanylate cyclase gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17170 SH03_RS17175 SH03_17180 SH03_RS17175 3480367 3480849 + OM lipoprotein positive effector of YfiN activity gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17175 SH03_RS17180 SH03_17185 SH03_RS17180 3480925 3481272 - 50S ribosomal protein L19 gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17180 SH03_RS17185 SH03_17190 trmD trmD 3481314 3482081 - tRNA (guanine-N(1)-)-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17185 SH03_RS17190 SH03_17195 rimM rimM 3482112 3482660 - ribosome maturation factor RimM Essential for efficient processing of 16S rRNA gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17190 SH03_RS17195 SH03_17200 SH03_RS17195 3482679 3482927 - 30S ribosomal protein S16 gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17195 SH03_RS17200 SH03_17205 SH03_RS17200 3483176 3484537 - signal recognition particle protein gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17200 SH03_RS17205 SH03_17210 SH03_RS17205 3484704 3485495 + hypothetical protein gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17205 SH03_RS17210 SH03_17215 SH03_RS17210 3485561 3486802 + membrane protein gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17210 SH03_RS17215 SH03_17220 SH03_RS17215 3486857 3487450 - protein GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17215 SH03_RS17220 SH03_17225 SH03_RS17220 3487447 3487611 - heat-shock protein gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17220 SH03_RS17225 SH03_17230 ppnK ppnK 3487573 3488451 + NAD kinase catalyzes the phosphorylation of NAD to NADP gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17225 SH03_RS17230 SH03_17235 SH03_RS17230 3488537 3490198 + DNA repair protein RecN gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17230 SH03_RS17235 SH03_17240 SH03_RS17235 3490347 3490688 + outer membrane protein assembly factor BamE gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17235 SH03_RS17240 SH03_17245 SH03_RS17240 3490750 3491040 - hypothetical protein gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17240 SH03_RS17245 SH03_17250 SH03_RS17245 3491030 3491506 - ribosome association toxin RatA gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17245 SH03_RS17250 SH03_17255 smpB smpB 3491638 3492120 + SsrA-binding protein binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes%3B also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site%3B SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus%3B both the tmRNA and SmpB are regulated in cell cycle-dependent manner%3B functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17250 SH03_RS17255 SH03_17260 SH03_RS17255 3492901 3494142 + integrase gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17255 SH03_RS17260 SH03_17265 SH03_RS17260 3494386 3495261 - hypothetical protein gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17260 SH03_RS17265 SH03_17270 SH03_RS17265 3495386 3495598 + regulator AlpA gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17265 SH03_RS17270 SH03_17275 SH03_RS17270 3495727 3497136 + hypothetical protein gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17270 SH03_RS17275 SH03_17280 SH03_RS17275 3497289 3497915 + hypothetical protein gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17275 SH03_RS17280 SH03_17285 SH03_RS17280 3498093 3500282 - DEAD/DEAH box helicase gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17280 SH03_RS17285 SH03_17290 SH03_RS17285 3500279 3501895 - CP4-57 defective prophage%2C DUF4297/DUF1837 polymorphic toxin family protein gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17285 SH03_RS17290 SH03_17295 SH03_RS17290 3502255 3502518 - hypothetical protein gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17290 SH03_RS17295 SH03_17300 SH03_RS17295 3502660 3503733 + mRNA endoribonuclease LS gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17295 SH03_RS17300 SH03_17305 SH03_RS17300 3503726 3504097 + antitoxin RnlB gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17300 SH03_RS17305 SH03_17310 SH03_RS17305 3504452 3505315 + hypothetical protein gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17305 SH03_RS17310 SH03_17315 SH03_RS17310 3505407 3506228 + UPF0380 protein YfjQ gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17310 SH03_RS17315 SH03_17320 SH03_RS17315 3506445 3507146 + transcriptional regulator gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17315 SH03_RS17320 SH03_17325 SH03_RS17320 3507187 3507423 + hypothetical protein gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17320 SH03_RS17325 SH03_17330 SH03_RS17325 3507423 3507866 + hypothetical protein gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17325 SH03_RS17330 SH03_17335 SH03_RS17330 3507890 3508357 + periplasmic protein gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17330 SH03_RS17335 SH03_17340 SH03_RS17335 3508582 3508896 - arsenate reductase gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17335 SH03_RS17340 SH03_RS17340 SH03_RS17340 3508909 3509924 - arsenic transporter gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17340 SH03_RS17345 SH03_17350 SH03_RS17345 3510060 3511763 + hypothetical protein gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17345 SH03_RS17350 SH03_17355 SH03_RS17350 3512661 3513119 + antirestriction protein gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17350 SH03_RS17355 SH03_17360 SH03_RS17355 3513128 3513610 + DNA repair protein gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17355 SH03_RS17360 SH03_17365 SH03_RS17360 3513857 3514174 + hypothetical protein gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17360 SH03_RS17365 SH03_17370 SH03_RS17365 3514195 3514524 + toxin YpjF gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17365 SH03_RS17370 SH03_17375 SH03_RS17370 3514888 3515100 - ATPase gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17370 SH03_RS17380 SH03_17385 SH03_RS17380 3519807 3519950 - DNA invertase gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17380 SH03_RS17385 SH03_17390 SH03_RS17385 3520380 3521171 - hypothetical protein gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17385 SH03_RS17390 SH03_17395 SH03_RS17390 3521271 3521753 - hypothetical protein gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17390 SH03_RS17400 SH03_17405 SH03_RS17400 3522504 3522579 - tRNA-Met tRNA gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17400 SH03_RS17405 SH03_17410 SH03_RS17405 3523490 3524176 + alpha-1%2C2-mannosidase gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17405 SH03_RS17410 SH03_17415 SH03_RS17410 3524189 3524980 + alpha-amylase gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17410 SH03_RS17415 SH03_17420 SH03_RS17415 3525119 3525391 + alpha-amylase gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17415 SH03_RS17420 SH03_17425 SH03_RS17420 3525727 3526704 + protein CsiD in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP%3B the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases%3B forms homotetramers in solution gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17420 SH03_RS17425 SH03_17430 SH03_RS17425 3526724 3527992 + L-2-hydroxyglutarate oxidase LhgO catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17425 SH03_RS17430 SH03_17435 gabD gabD 3528015 3529463 + succinate-semialdehyde dehydrogenase [NADP+] catalyzes the formation of succinate from succinate semialdehyde%3B NADP dependent gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17430 SH03_RS17435 SH03_17440 SH03_RS17435 3529477 3530757 + 4-aminobutyrate aminotransferase GabT gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17435 SH03_RS17440 SH03_17445 SH03_RS17440 3530995 3532395 + GABA permease gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17440 SH03_RS17445 SH03_17450 SH03_RS17445 3532416 3533078 + transcriptional regulator regulator of gab gene expression gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17445 SH03_RS17450 SH03_17455 SH03_RS17450 3533079 3533528 - peptidoglycan-binding protein LysM gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17450 SH03_RS17455 SH03_17460 SH03_RS17455 3533612 3533770 - hypothetical protein gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17455 SH03_RS17460 SH03_17465 SH03_RS17460 3533953 3534252 + transcriptional regulator gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17460 SH03_RS17465 SH03_17470 SH03_RS17465 3534262 3534786 + hypothetical protein gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17465 SH03_RS17470 SH03_17475 SH03_RS17470 3534833 3535237 - DNA-binding protein StpA gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17470 SH03_RS17475 SH03_17480 SH03_RS17475 3535906 3536355 + L-alanine exporter AlaE gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17475 SH03_RS17480 SH03_17485 SH03_RS17480 3536392 3536736 - hypothetical protein gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17480 SH03_RS17485 SH03_17490 SH03_RS17485 3536888 3537217 + DUF883 domain-containing protein gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17485 SH03_RS17490 SH03_17495 SH03_RS17490 3537465 3537710 + glutaredoxin gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17490 SH03_RS17495 SH03_17500 nrdI nrdI 3537707 3538117 + protein NrdI in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17495 SH03_RS17500 SH03_17505 SH03_RS17500 3538090 3540234 + ribonucleoside-diphosphate reductase 2 subunit alpha gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17500 SH03_RS17505 SH03_17510 SH03_RS17505 3540244 3541203 + ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1b enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdE gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17505 SH03_RS17510 SH03_17515 SH03_RS17510 3541557 3542759 + glycine/betaine ABC transporter ATP-binding protein with ProWX is involved in the high-affinity uptake of glycine betaine gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17510 SH03_RS17515 SH03_17520 SH03_RS17515 3542752 3543816 + glycine/betaine ABC transporter permease with ProVX is involved in the high-affinity uptake of glycine betaine gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17515 SH03_RS17520 SH03_17525 proX proX 3543874 3544866 + glycine/betaine ABC transporter substrate-binding protein with ProVW%2C part of the high-affinity transport system for the osmoprotectant glycine betaine gene gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17520 SH03_RS17525 SH03_RS17525 SH03_RS17525 3545058 3546235 + transporter gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17525 SH03_RS17530 SH03_17535 SH03_RS17530 3546359 3547096 + hypothetical protein gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17530 SH03_RS17535 SH03_17540 SH03_RS17535 3547086 3547421 + L-valine exporter%2C norvaline resistance protein gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17535 SH03_RS17540 SH03_17545 SH03_RS17540 3547512 3548042 + transcriptional regulator DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux%3B negative regulator of the multidrug operon emrAB gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17540 SH03_RS17545 SH03_17550 SH03_RS17545 3548169 3549341 + multidrug export protein EmrA with ErmA and TolC forms a multidrug efflux system gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17545 SH03_RS17550 SH03_17555 emrB emrB 3549358 3550896 + multidrug effux MFS transporter subunit EmrB multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17550 SH03_RS17555 SH03_17560 SH03_RS17555 3550960 3551475 - S-ribosylhomocysteine lyase catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17555 SH03_RS17560 SH03_17565 SH03_RS17560 3551625 3553181 - glutamate--cysteine ligase involved in the first step of glutathione biosynthesis gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17560 SH03_RS17565 SH03_17570 SH03_RS17565 3553254 3553682 - hypothetical protein gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17565 SH03_RS17570 SH03_17575 SH03_RS17570 3553679 3554245 - fructose-1-phosphate phosphatase YqaB YqaB%3B catalyzes the dephosphorylation of fructose 1-phosphate%2C 6-phosphogluconate and p-nitrophenyl phosphate (pNPP)%3B presents beta-phosphoglucomutase activity at a lower extent gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17570 SH03_RS17580 SH03_17585 SH03_RS17580 3554526 3554602 - tRNA-Arg tRNA gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17580 SH03_RS17585 SH03_17590 SH03_RS17585 3554801 3554877 - tRNA-Arg tRNA gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17585 SH03_RS17590 SH03_17595 SH03_RS17590 3554940 3555016 - tRNA-Arg tRNA gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17590 SH03_RS17595 SH03_17600 SH03_RS17595 3555215 3555291 - tRNA-Arg tRNA gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17595 SH03_RS17600 SH03_17605 SH03_RS17600 3555295 3555387 - tRNA-Ser tRNA gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17600 SH03_RS17605 SH03_17610 SH03_RS17605 3555703 3555888 - pleiotropic regulatory protein for carbon source metabolism affects carbohydrate metabolism%3B has regulatory role in many processes gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17605 SH03_RS17610 SH03_17615 SH03_RS17610 3556123 3558753 - alanine--tRNA ligase gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17610 SH03_RS17615 SH03_17620 SH03_RS17615 3558691 3558840 + hypothetical protein gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17615 SH03_RS17620 SH03_17625 recX recX 3558881 3559381 - regulatory protein RecX binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17620 SH03_RS17625 SH03_RS17625 SH03_RS17625 3559603 3559787 - cruciferin gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17625 SH03_RS17630 SH03_RS17630 SH03_RS17630 3559905 3560051 - hypothetical protein gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17630 SH03_RS17635 SH03_17645 SH03_RS17635 3560105 3560764 + chloramphenicol acetyltransferase CAT gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17635 SH03_RS17640 SH03_17650 SH03_RS17640 3560930 3561427 - nicotinamide-nucleotide amidohydrolase PncC gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17640 SH03_RS17645 SH03_17655 SH03_RS17645 3561572 3562657 - murein transglycosylase membrane-bound lytic murein transglycosylase B%3B catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17645 SH03_RS17650 SH03_17660 srlA srlA 3562913 3563476 + glucitol/sorbitol permease IIC component catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17650 SH03_RS17655 SH03_17665 srlE srlE 3563473 3564432 + glucitol/sorbitol-specific phosphotransferase enzyme IIB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIB transfers the phosphoryl group to the substrate gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17655 SH03_RS17660 SH03_17670 SH03_RS17660 3564443 3564814 + glucitol/sorbitol-specific phosphotransferase enzyme IIA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17660 SH03_RS17665 SH03_17675 SH03_RS17665 3564818 3565597 + sorbitol-6-phosphate 2-dehydrogenase catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17665 SH03_RS17670 SH03_17680 SH03_RS17670 3565702 3566061 + glucitol operon activator protein regulator for glucitol utilization gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17670 SH03_RS17675 SH03_17685 srlR srlR 3566128 3566901 + glucitol operon repressor regulates genes involved in glucitol utilization gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17675 SH03_RS17680 SH03_17690 SH03_RS17680 3566894 3567859 + arabinose 5-phosphate isomerase GutQ gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17680 SH03_RS17685 SH03_17695 SH03_RS17685 3567856 3569370 - NorR family transcriptional regulator Required for the expression of anaerobic nitric oxide (NO) reductase%3B acts as a transcriptional activator for the norVW operon gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17685 SH03_RS17690 SH03_17700 SH03_RS17690 3569557 3570996 + anaerobic nitric oxide reductase flavorubredoxin detoxifies nitric oxide using NADH gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17690 SH03_RS17695 SH03_17705 SH03_RS17695 3570993 3572126 + nitric oxide reductase FlRd-NAD+ reductase gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17695 SH03_RS17700 SH03_17710 SH03_RS17700 3572254 3574506 - hydrogenase maturation protein HypF carbamoyltransferase%3B involved in the formation of the cyanate group of hydrogenase%3B catalyzes the formation of carbamoyladenylate from carbamoylphosphate and then transfers the carbamoyl group to HypE gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17700 SH03_RS17705 SH03_17715 SH03_RS17705 3574659 3575186 - electron transporter HydN involved in electron transport from formate to hydrogen gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17705 SH03_RS17710 SH03_17720 SH03_RS17710 3575335 3576345 - transcriptional regulator gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17710 SH03_RS17715 SH03_17725 SH03_RS17715 3576605 3578062 + PTS arbutin-%2C cellobiose-%2C and salicin EIIBC component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17715 SH03_RS17720 SH03_17730 SH03_RS17720 3578071 3579495 + 6-phospho-beta-glucosidase gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17720 SH03_RS17725 SH03_17735 hycI hycI 3579654 3580124 - hydrogenase 3 maturation protease involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17725 SH03_RS17730 SH03_17740 SH03_RS17730 3580117 3580527 - formate hydrogenlyase maturation protein HycH required for the maturation of the formate hydrogenlyase complex gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17730 SH03_RS17735 SH03_17745 SH03_RS17735 3580524 3581291 - formate hydrogenlyase subunit 7 gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17735 SH03_RS17740 SH03_17750 SH03_RS17740 3581291 3581833 - formate hydrogenlyase subunit 6 electron transfer protein for hydrogenase-3%3B the formate hydrogenlyase complex comprises of a formate dehydrogenase%2C unidentified electron carriers and hydrogenase-3%3B in this non-energy conserving pathway%2C molecular hydrogen and carbodioxide are released from formate gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17740 SH03_RS17745 SH03_17755 hycE hycE 3581843 3583552 - formate hydrogenlyase subunit 5 formate hydrogenlyase subunit 5%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17745 SH03_RS17750 SH03_17760 hycD hycD 3583570 3584493 - formate hydrogenlyase subunit 4 formate hydrogenlyase subunit 4%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17750 SH03_RS17755 SH03_17765 SH03_RS17755 3584496 3586322 - formate hydrogenlyase subunit 3 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen%3B formate hydrogenlyase comprises of a formate dehydrogenase%2C unidentified electron carriers and a hydrogenase (subunit 3) gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17755 SH03_RS17760 SH03_17770 SH03_RS17760 3586319 3586930 - formate hydrogenlyase subunit 2 gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17760 SH03_RS17765 SH03_17775 SH03_RS17765 3586831 3587139 + hypothetical protein gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17765 SH03_RS17770 SH03_17780 SH03_RS17770 3587055 3587516 - formate hydrogenlyase regulatory protein HycA regulates several genes involved in the formate hydrogenlyase system%3B seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17770 SH03_RS17775 SH03_17785 hypA hypA 3587728 3588078 + protein HypA plays a role in hydrogenase nickel cofactor insertion gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17775 SH03_RS17780 SH03_17790 SH03_RS17780 3588082 3588954 + hydrogenase isoenzymes nickel incorporation protein HypB GTP hydrolase involved in nickel liganding into hydrogenases gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17780 SH03_RS17785 SH03_17795 SH03_RS17785 3588945 3589217 + hydrogenase assembly protein HypC HypC%3B accessory protein necessary for maturation of the hydrogenase isoforms 1%2C 2 and 3%3B forms a complex with HypD%2C HypE%2C and HypF proteins%2C which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17785 SH03_RS17790 SH03_17800 SH03_RS17790 3589217 3590338 + hydrogenase isoenzymes formation protein HypD necessary for the synthesis of all three hydrogenase isoenzymes gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17790 SH03_RS17795 SH03_17805 SH03_RS17795 3590335 3591345 + hydrogenase isoenzymes formation protein HypE hydrogenase isoenzymes formation protein%3B involved in the formation of the cyanate group of the large subunit of the hydrogenase%3B catalyzes the formation of thiocyanate from thiocarbamate gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17795 SH03_RS17800 SH03_17810 SH03_RS17800 3591419 3593497 + formate hydrogenlyase transcriptional activator regulates the expression of formate dehydrogenase H and hydrogenase-3 structural genes gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17800 SH03_RS17805 SH03_17815 SH03_RS17805 3593534 3593887 - hypothetical protein gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17805 SH03_RS17810 SH03_17820 SH03_RS17810 3594174 3596735 + DNA mismatch repair protein MutS This protein performs the mismatch recognition step during the DNA repair process gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17810 SH03_RS17815 SH03_17825 SH03_RS17815 3596841 3597497 + Serine/threonine-protein phosphatase 2 gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17815 SH03_RS17820 SH03_17830 SH03_RS17820 3597548 3598315 - DeoR family transcriptional regulator gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17820 SH03_RS17825 SH03_17835 SH03_RS17825 3598511 3599419 + dehydrogenase gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17825 SH03_RS17830 SH03_17840 SH03_RS17830 3599416 3600582 + DUF1537 domain-containing protein gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17830 SH03_RS17835 SH03_17845 SH03_RS17835 3600674 3601312 + aldolase gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17835 SH03_RS17840 SH03_17850 SH03_RS17840 3601317 3602093 + hydroxypyruvate isomerase gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17840 SH03_RS17845 SH03_17855 SH03_RS17845 3602182 3603546 + permease member of the Gnt family of gluconate transporters%3B not involved in gluconate transport%3B unknown function gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17845 SH03_RS17850 SH03_17860 SH03_RS17850 3603640 3604632 - RNA polymerase sigma factor RpoS sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor controls a regulon of genes required for protection against external stresses gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17850 SH03_RS17855 SH03_17865 nlpD nlpD 3604695 3605834 - murein hydrolase activator NlpD outer membrane lipoprotein involved in stationary-phase cell survival%3B similar to LppB virulence determinant from Haemophilus somnus gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17855 SH03_RS17860 SH03_17870 pcm pcm 3605974 3606600 - protein-L-isoaspartate O-methyltransferase catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17860 SH03_RS17865 SH03_17875 surE surE 3606594 3607355 - 5'/3'-nucleotidase SurE broad specificity 5'(3')-nucleotidase and polyphosphatase gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17865 SH03_RS17870 SH03_17880 truD truD 3607336 3608385 - tRNA pseudouridine synthase D catalyzes the modification of U13 in tRNA(Glu) gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17870 SH03_RS17875 SH03_17885 ispF ispF 3608382 3608861 - 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17875 SH03_RS17880 SH03_17890 SH03_RS17880 3608861 3609571 - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17880 SH03_RS17885 SH03_17895 ftsB ftsB 3609590 3609901 - cell division protein FtsB forms a complex with FtsL and FtsQ%3B colocalizes to the septal region of the dividing cell%3B membrane protein gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17885 SH03_RS17890 SH03_17900 SH03_RS17890 3610095 3610418 - hypothetical protein gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17890 SH03_RS17895 SH03_17905 SH03_RS17895 3610468 3611073 - adenylyl-sulfate kinase converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis gene gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17895 SH03_RS17900 SH03_17910 cysN cysN 3611073 3612500 - sulfate adenylyltransferase subunit 1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step%3B forms a heterodimer with CysD%3B part of the GTP-binding elongation factor family CysN/NodQ gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17900 SH03_RS17905 SH03_17915 SH03_RS17905 3612502 3613410 - sulfate adenylyltransferase subunit 2 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17905 SH03_RS17910 SH03_17920 SH03_RS17910 3613662 3614699 + alkaline phosphatase isozyme conversion protein catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17910 SH03_RS17915 SH03_17925 SH03_RS17915 3615650 3615934 - CRISPR-associated endonuclease Cas2 gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17915 SH03_RS17920 SH03_17930 SH03_RS17920 3615936 3616853 - subtype I-E CRISPR-associated endonuclease Cas1 gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17920 SH03_RS17925 SH03_17935 SH03_RS17925 3616869 3617468 - CRISPR system Cascade subunit CasE gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17925 SH03_RS17930 SH03_17940 SH03_RS17930 3617455 3618129 - CRISPR system Cascade subunit CasD gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17930 SH03_RS17935 SH03_17945 SH03_RS17935 3618132 3619223 - CRISPR system Cascade subunit CasC gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17935 SH03_RS17940 SH03_17950 SH03_RS17940 3619236 3619718 - CRISPR system Cascade subunit CasB gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17940 SH03_RS17945 SH03_17955 SH03_RS17945 3619711 3621219 - CRISPR system Cascade subunit CasA CRISP RNA (crRNA) containing protein gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17945 SH03_RS17950 SH03_17960 SH03_RS17950 3621634 3624300 - CRISPR-associated endonuclease/helicase Cas3 required for the activity of the Cascade antiviral complex gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17950 SH03_RS17955 SH03_17965 SH03_RS17955 3624659 3625393 - phosphoadenosine phosphosulfate reductase catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17955 SH03_RS17960 SH03_17970 SH03_RS17960 3625468 3627180 - sulfite reductase subunit beta hemoprotein%3B NADPH dependent%3B with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17960 SH03_RS17965 SH03_17975 cysJ cysJ 3627180 3628979 - sulfite reductase subunit alpha catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate%3B a flavoprotein with flavin reductase activity gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17965 SH03_RS17970 SH03_17980 SH03_RS17970 3629298 3629660 + 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin synthase gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17970 SH03_RS17975 SH03_17985 SH03_RS17975 3629738 3631009 + electron transfer flavoprotein-quinone oxidoreductase gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17975 SH03_RS17980 SH03_17990 SH03_RS17980 3631000 3631260 + ferredoxin-like protein YgcO gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17980 SH03_RS17985 SH03_17995 SH03_RS17985 3631277 3631852 + hypothetical protein gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17985 SH03_RS17990 SH03_18000 SH03_RS17990 3632000 3632860 - flavoprotein gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17990 SH03_RS17995 SH03_18005 SH03_RS17995 3632857 3633636 - flavoprotein gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS17995 SH03_RS18000 SH03_18010 SH03_RS18000 3633614 3634951 - metabolite transporter gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18000 SH03_RS18005 SH03_18015 SH03_RS18005 3635045 3636499 - FAD-linked oxidoreductase gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18005 SH03_RS18010 SH03_18020 SH03_RS18010 3636569 3637354 - SDR family oxidoreductase gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18010 SH03_RS18015 SH03_18025 SH03_RS18015 3637673 3638950 + hypothetical protein gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18015 SH03_RS18020 SH03_18030 SH03_RS18020 3638977 3640455 + kinase gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18020 SH03_RS18025 SH03_18035 SH03_RS18025 3641828 3642499 - 7-carboxy-7-deazaguanine synthase gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18025 SH03_RS18030 SH03_18040 SH03_RS18030 3642638 3642778 + membrane stress resistance protein gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18030 SH03_RS18035 SH03_18045 SH03_RS18035 3642792 3643664 + TPM domain protein phosphatase gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18035 SH03_RS18040 SH03_18050 eno eno 3643724 3645022 - enolase catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18040 SH03_RS18045 SH03_18055 pyrG pyrG 3645110 3646747 - CTP synthase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18045 SH03_RS18050 SH03_18060 mazG mazG 3646975 3647766 - nucleoside triphosphate pyrophosphohydrolase functions in degradation of stringent response intracellular messenger ppGpp%3B in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF%3B activity of MazG is inhibited by MazEF in vitro%3B ppGpp inhibits mazEF expression%3B MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation%3B MazG also interacts with the GTPase protein Era gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18050 SH03_RS18055 SH03_18065 SH03_RS18055 3647837 3648172 - mRNA interferase MazF ChpA%3B endoribonuclease%3B toxin of the MazF-MazE (ChpA-ChpR) toxin-antitoxin system gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18055 SH03_RS18060 SH03_18070 SH03_RS18060 3648172 3648420 - antitoxin MazE part of the MazF-MazE toxin-antitoxin system%3B conteracts MazF gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18060 SH03_RS18065 SH03_18075 relA relA 3648498 3650732 - GTP pyrophosphokinase (p)ppGpp synthetase%3B catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18065 SH03_RS18070 SH03_18080 rumA rumA 3650780 3652081 - 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA%3B binds an iron-sulfur cluster [4Fe-4S] gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18070 SH03_RS18075 SH03_18085 SH03_RS18075 3652138 3654894 + signal transduction histidine kinase part of the two-component regulatory system with UvrY%3B involved in the regulation of carbon metabolism via the csrA/csrB regulatory system gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18075 SH03_RS18080 SH03_18090 gudD gudD 3655126 3656466 - glucarate dehydratase catalyzes the formation of 5-keto-4-deoxy-D-glucarate from glucarate gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18080 SH03_RS18085 SH03_18095 SH03_RS18085 3656487 3657827 - glucarate dehydratase-related protein gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18085 SH03_RS18090 SH03_18100 SH03_RS18090 3657829 3659181 - glucarate transporter gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18090 SH03_RS18095 SH03_18105 SH03_RS18095 3659616 3660065 - flavodoxin An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18095 SH03_RS18100 SH03_18110 SH03_RS18100 3660083 3660865 - tRNA pseudouridine synthase C catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18100 SH03_RS18105 SH03_18115 SH03_RS18105 3660865 3661194 - DUF446 domain-containing protein gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18105 SH03_RS18110 SH03_RS18110 SH03_RS18110 3661441 3661566 - hypothetical protein gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18110 SH03_RS18115 SH03_18125 SH03_RS18115 3661816 3662361 - protein Syd SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18115 SH03_RS18120 SH03_18130 queF queF 3662429 3663277 + NADPH-dependent 7-cyano-7-deazaguanine reductase catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18120 SH03_RS18125 SH03_18135 SH03_RS18125 3663389 3664753 + LOG family protein gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18125 SH03_RS18130 SH03_18140 SH03_RS18130 3665310 3666599 + serine transporter gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18130 SH03_RS18135 SH03_18145 SH03_RS18135 3666657 3668024 + L-serine dehydratase 2 catalyzes the formation of pyruvate from serine gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18135 SH03_RS18140 SH03_18150 SH03_RS18140 3668136 3668891 + flap endonuclease Xni similar to flap endonuclease%3B FEN family%3B protein from E. coli does not have exonuclease activity gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18140 SH03_RS18145 SH03_18155 SH03_RS18145 3668946 3670094 - lactaldehyde reductase gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18145 SH03_RS18150 SH03_18160 SH03_RS18150 3670122 3670769 - L-fuculose phosphate aldolase catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18150 SH03_RS18155 SH03_18165 SH03_RS18155 3671316 3672632 + L-fucose-proton symporter gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18155 SH03_RS18160 SH03_18170 fucI fucI 3672665 3674440 + L-fucose isomerase catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18160 SH03_RS18165 SH03_18175 SH03_RS18165 3674549 3675967 + L-fuculokinase gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18165 SH03_RS18170 SH03_18180 SH03_RS18170 3675969 3676391 + L-fucose mutarotase gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18170 SH03_RS18175 SH03_18185 SH03_RS18175 3676449 3677180 + l-fucose operon activator regulates expression of genes involved in L-fucose utilization gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18175 SH03_RS18180 SH03_18190 SH03_RS18180 3677224 3678324 - ribosomal RNA large subunit methyltransferase M gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18180 SH03_RS18185 SH03_18195 SH03_RS18185 3678317 3678712 - hypothetical protein gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18185 SH03_RS18190 SH03_18200 SH03_RS18190 3678731 3679648 - glycine cleavage system transcriptional activator Glycine cleavage system transcriptional activator%3B activates the gcvTHP operon in the presence of glycine and represses the operon in its absence gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18190 SH03_RS18195 SH03_18205 SH03_RS18195 3679999 3680226 - DUF903 domain-containing protein gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18195 SH03_RS18200 SH03_18210 SH03_RS18200 3680418 3681623 + cysteine desulfurase CsdA gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18200 SH03_RS18205 SH03_18215 SH03_RS18205 3681623 3682066 + sulfur acceptor protein CsdE binds and activates CsdA%3B Fe-S protein gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18205 SH03_RS18210 SH03_18220 SH03_RS18210 3682117 3682923 - tRNA threonylcarbamoyladenosine dehydratase accepts sulfur from CsdA gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18210 SH03_RS18215 SH03_18225 mltA mltA 3683162 3684259 - murein transglycosylase membrane-bound%2C lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18215 SH03_RS18220 SH03_18230 SH03_RS18220 3684468 3684544 + tRNA-Met tRNA gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18220 SH03_RS18225 SH03_18235 SH03_RS18225 3684578 3684654 + tRNA-Met tRNA gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18225 SH03_RS18230 SH03_18240 SH03_RS18230 3684688 3684764 + tRNA-Met tRNA gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18230 SH03_RS18235 SH03_18245 amiC amiC 3684838 3686091 - N-acetylmuramoyl-L-alanine amidase hydrolyzes the bond between N-acetylmuramic acid and amino acid residues in peptidoglycan gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18235 SH03_RS18240 SH03_18250 SH03_RS18240 3686323 3687654 + N-acetylglutamate synthase catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18240 SH03_RS18245 SH03_RS18245 recD recD 3687716 3689542 - exonuclease V subunit alpha helicase/nuclease%3B with RecBC catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18245 SH03_RS18250 SH03_18260 recB recB 3689542 3693084 - RecBCD enzyme subunit RecB helicase/nuclease%3B with RecCD catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18250 SH03_RS18255 SH03_18265 SH03_RS18255 3693077 3695965 - protease 3 degrades small peptides gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18255 SH03_RS18260 SH03_18270 recC recC 3696141 3699509 - RecBCD enzyme subunit RecC catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides%3B component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18260 SH03_RS18265 SH03_18275 SH03_RS18265 3699522 3699845 - prepilin peptidase-dependent protein C gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18265 SH03_RS18270 SH03_18280 SH03_RS18270 3699830 3700237 - DUF2509 domain-containing protein gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18270 SH03_RS18275 SH03_18285 SH03_RS18275 3700234 3700797 - prepilin peptidase-dependent protein B gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18275 SH03_RS18280 SH03_18290 SH03_RS18280 3700788 3701258 - prepilin peptidase-dependent protein A gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18280 SH03_RS18285 SH03_18295 SH03_RS18285 3701442 3702236 - thymidylate synthase gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18285 SH03_RS18290 SH03_18300 SH03_RS18290 3702243 3703118 - prolipoprotein diacylglyceryl transferase gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18290 SH03_RS18295 SH03_18305 SH03_RS18295 3703269 3705515 - phosphoenolpyruvate-protein phosphotransferase PtsP member of a second PTS chain involved in nitrogen metabolism%3B PtsP phosphorylates NPr gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18295 SH03_RS18300 SH03_18310 SH03_RS18300 3705528 3706058 - RNA pyrophosphohydrolase hydrolyzes diadenosine polyphosphate gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18300 SH03_RS18305 SH03_18315 SH03_RS18305 3706370 3706564 + hypothetical protein gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18305 SH03_RS18310 SH03_18320 SH03_RS18310 3706503 3706664 + hypothetical protein gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18310 SH03_RS18315 SH03_18325 SH03_RS18315 3706743 3707432 + DNA mismatch repair protein MutH MutH%3B Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18315 SH03_RS18320 SH03_18330 SH03_RS18320 3707501 3708214 + membrane protein gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18320 SH03_RS18325 SH03_18335 SH03_RS18325 3708352 3708570 + hypothetical protein gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18325 SH03_RS18330 SH03_18340 tas tas 3708678 3709718 + protein tas complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain%3B member of the aldo/keto reductase 2 family%3B crystal structure of purified Escherichia coli protein shows bound NADPH gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18330 SH03_RS18335 SH03_18345 SH03_RS18335 3709750 3710943 - lysophospholipid transporter LplT gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18335 SH03_RS18340 SH03_18350 SH03_RS18340 3710936 3713095 - bifunctional protein Aas Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18340 SH03_RS18345 SH03_18355 SH03_RS18345 3713680 3714711 + transcriptional regulator controls transcription of galETKM gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18345 SH03_RS18350 SH03_18360 SH03_RS18350 3714718 3715980 - diaminopimelate decarboxylase catalyzes the decarboxylation of diaminopimelate into lysine%3B pyridoxal phosphate(PLP)-binding gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18350 SH03_RS18355 SH03_18365 SH03_RS18355 3716102 3717037 + LysR family transcriptional regulator activates the transcription of the lysA gene encoding diaminopimelate decarboxylase gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18355 SH03_RS18360 SH03_18370 SH03_RS18360 3717024 3717716 - Asp/Glu_racemase gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18360 SH03_RS18365 SH03_18375 SH03_RS18365 3717845 3719263 - D-galactose transporter gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18365 SH03_RS18370 SH03_18380 SH03_RS18370 3719578 3720339 - 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18370 SH03_RS18375 SH03_18385 SH03_RS18375 3720369 3721205 - 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase%3B catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2%2C5-hexodiulosonate gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18375 SH03_RS18380 SH03_18390 SH03_RS18380 3721492 3722673 - acetyl-CoA acetyltransferase gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18380 SH03_RS18385 SH03_18395 SH03_RS18385 3722928 3724157 + transporter gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18385 SH03_RS18390 SH03_18400 SH03_RS18390 3724731 3725249 + LuxR family transcriptional regulator gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18390 SH03_RS18395 SH03_18405 SH03_RS18395 3725583 3726392 + transcriptional regulator gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18395 SH03_RS18400 SH03_18410 SH03_RS18400 3726385 3726867 + hypothetical protein gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18400 SH03_RS18405 SH03_18415 SH03_RS18405 3727016 3727441 - hypothetical protein gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18405 SH03_RS18410 SH03_RS18410 SH03_RS18410 3727635 3728124 + hypothetical protein gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18410 SH03_RS18415 SH03_18425 SH03_RS18415 3728349 3728840 + SycD-like chaperone family hypothetical protein gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18415 SH03_RS18420 SH03_18430 SH03_RS18420 3729175 3730551 + transcriptional regulator gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18420 SH03_RS18425 SH03_18435 SH03_RS18425 3730719 3730937 + hypothetical protein gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18425 SH03_RS18430 SH03_18440 SH03_RS18430 3731122 3731496 + lytic transglycosylase gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18430 SH03_RS18435 SH03_18445 SH03_RS18435 3731541 3731987 - LuxR family transcriptional regulator gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18435 SH03_RS18440 SH03_18450 SH03_RS18440 3732018 3732173 - transcriptional regulator gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18440 SH03_RS18445 SH03_18455 SH03_RS18445 3732395 3732826 - hypothetical protein gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18445 SH03_RS18450 SH03_18460 SH03_RS18450 3732829 3733101 - hypothetical protein gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18450 SH03_RS18455 SH03_18465 SH03_RS18455 3733043 3733198 - secretion protein gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18455 SH03_RS18460 SH03_18470 SH03_RS18460 3733453 3734358 - integrase gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18460 SH03_RS18465 SH03_18475 SH03_RS18465 3734316 3734681 - transposase represses IS2 gene transcription gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18465 SH03_RS18470 SH03_18480 SH03_RS18470 3734770 3735069 - hypothetical protein gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18470 SH03_RS18475 SH03_18485 SH03_RS18475 3735115 3735909 - hypothetical protein gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18475 SH03_RS18480 SH03_18490 SH03_RS18480 3736065 3736138 - tRNA-Gly tRNA gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18480 SH03_RS18485 SH03_18495 SH03_RS18485 3736217 3736972 - peptidoglycan-binding protein LysM gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18485 SH03_RS18490 SH03_18500 SH03_RS18490 3737387 3739684 + xanthine dehydrogenase subunit A molybdenum cofactor-binding protein%3B participates in purine salvage gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18490 SH03_RS18495 SH03_18505 SH03_RS18495 3739695 3740573 + xanthine dehydrogenase FAD-binding subunit FAD-binding subunit%3B with XdhA and XdhC participates in purine salvage gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18495 SH03_RS18500 SH03_18510 SH03_RS18500 3740570 3741049 + xanthine dehydrogenase iron-sulfur-binding subunit iron-sulfur-binding subunit%3B with XdhA and XdhB participates in purine salvage gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18500 SH03_RS18505 SH03_18515 SH03_RS18505 3741089 3742867 - sigma-54-interacting transcriptional activator gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18505 SH03_RS18510 SH03_18520 SH03_RS18510 3743346 3744533 + ornithine carbamoyltransferase gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18510 SH03_RS18515 SH03_18525 SH03_RS18515 3744591 3745787 + diaminopropionate ammonia-lyase catalyzes the formation of pyruvate from 2%2C3-diaminopropionate gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18515 SH03_RS18520 SH03_18530 SH03_RS18520 3745845 3747056 + peptidase Zn-dependent extracellular dipeptidase%3B similar to succinyl-diaminopimelate desuccinylases gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18520 SH03_RS18525 SH03_18535 SH03_RS18525 3747109 3748494 + D-phenylhydantoinase catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18525 SH03_RS18530 SH03_18540 SH03_RS18530 3748542 3749474 + carbamate kinase-like protein YqeA gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18530 SH03_RS18535 SH03_18545 SH03_RS18535 3749695 3751320 - XdhC-CoxI family protein with NAD(P)-binding Rossman fold gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18535 SH03_RS18540 SH03_18550 SH03_RS18540 3751368 3752138 - selenium-dependent hydroxylase accessory protein gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18540 SH03_RS18545 SH03_18555 SH03_RS18545 3752241 3752819 + molybdenum cofactor cytidylyltransferase gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18545 SH03_RS18550 SH03_18560 SH03_RS18550 3753141 3756239 + Fe-S subunit oxidoreductase subunit with YgfM and YgfN forms a selenate reductase%2C which seems to catalyze the reduction of selenate to selenite%3B YgfK mutants are unable to reduce selenate%3B involved in purine salvage process%3B seems to act as an oxidoreductase%2C but sequence similarity suggests it is a dihydrothymine dehydrogenase gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18550 SH03_RS18555 SH03_18565 SH03_RS18555 3756242 3757570 + protein SsnA in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18555 SH03_RS18560 SH03_18570 SH03_RS18560 3757621 3758400 + oxidoreductase gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18560 SH03_RS18565 SH03_18575 SH03_RS18565 3758397 3761267 + hypoxanthine oxidase XdhD gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18565 SH03_RS18570 SH03_18580 SH03_RS18570 3761432 3762832 + xanthine permease XanQ high-affinity transporter for xanthine gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18570 SH03_RS18575 SH03_18585 SH03_RS18575 3762850 3764166 + guanine deaminase Catalyzes the deamination of guanine gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18575 SH03_RS18580 SH03_18590 SH03_RS18580 3764202 3765569 + guanine/hypoxanthine permease GhxQ gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18580 SH03_RS18585 SH03_18595 SH03_RS18585 3765605 3766093 - oxidoreductase gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18585 SH03_RS18590 SH03_18600 SH03_RS18590 3766093 3768012 - oxidoreductase Fe-S subunit/nucleotide-binding subunit unknown function%3B in E. coli the aegA gene is regulated by Fnr%2C NarXL%2C and NarQ (but not ArcA)%2C induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18590 SH03_RS18595 SH03_RS18595 SH03_RS18595 3768315 3768503 + hypothetical protein gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18595 SH03_RS18600 SH03_18610 SH03_RS18600 3768448 3769896 + uric acid transporter UacT gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18600 SH03_RS18605 SH03_18615 SH03_RS18605 3769898 3770023 + hypothetical protein gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18605 SH03_RS18610 SH03_18620 SH03_RS18610 3770146 3770694 + isopentenyl-diphosphate delta isomerase catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18610 SH03_RS18615 SH03_18625 lysS lysS 3770738 3772255 - lysine--tRNA ligase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18615 SH03_RS18620 SH03_18630 SH03_RS18620 3772265 3773146 - peptide chain release factor 2 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18620 SH03_RS18625 SH03_18635 SH03_RS18625 3773454 3775187 - single-stranded-DNA-specific exonuclease RecJ 5'-3' single-stranded-DNA-specific exonuclease gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18625 SH03_RS18630 SH03_18640 SH03_RS18630 3775193 3775903 - thiol:disulfide interchange protein DsbC DsbC%3B periplasmic protein with protein disulfide isomerase activity%3B this protein also shows disulfide oxidoreductase activity gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18630 SH03_RS18635 SH03_18645 xerD xerD 3775928 3776824 - tyrosine recombinase XerD site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B XerD specifically exchanges the bottom strands%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18635 SH03_RS18640 SH03_18650 SH03_RS18640 3776936 3777457 + flavodoxin-2 An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18640 SH03_RS18645 SH03_18655 SH03_RS18645 3777497 3777904 - toxin CptA gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18645 SH03_RS18650 SH03_RS18650 SH03_RS18650 3777921 3778151 - hypothetical protein gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18650 SH03_RS18655 SH03_18665 ygfZ ygfZ 3778394 3779374 + tRNA-modifying protein YgfZ physiological role is not clear%3B not essential for growth but mutants grow poorly%3B mutations suppress hda null mutations%3B may be involved in regulation of ATP-DnaA levels%3B may also be involved in regulation of tRNA modifications%3B can bind folic acid and tetrahydrofolate%3B forms a three domain ring-like structure with a central channel%3B structurally similar to DMGO protein from A. globiformis%3B shows sequence similarity to yeast CAF17 transcriptional regulato%3B Hda supressor gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18655 SH03_RS18660 SH03_18670 SH03_RS18660 3779570 3780229 - hemolysin gene gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18660 SH03_RS18665 SH03_18675 SH03_RS18665 3780393 3780704 - hypothetical protein gene gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18665 SH03_RS18670 SH03_18680 SH03_RS18670 3780749 3782182 + 6-phospho-beta-glucosidase gene gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18670 SH03_RS18675 SH03_18685 SH03_RS18675 3782239 3782982 - NAD(P)-dependent oxidoreductase gene gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18675 SH03_RS18680 SH03_18690 SH03_RS18680 3783249 3786122 - glycine dehydrogenase (decarboxylating) acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18680 SH03_RS18685 SH03_18695 SH03_RS18685 3786241 3786630 - glycine cleavage system protein H part of multienzyme complex composed of H%2C L%2C P%2C and T proteins which catalyzes oxidation of glycine to yield carbon dioxide%2C ammonia%2C 5%2C10-CH2-H4folate and a reduced pyridine nucleotide%3B protein H is involved in transfer of methylamine group from the P to T protein%3B covalently bound to a lipoyl cofactor gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18685 SH03_RS18690 SH03_18700 gcvT gcvT 3786654 3787748 - aminomethyltransferase catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate%2C causing the release of ammonia and the generation of reduced GcvH protein gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18690 SH03_RS18695 SH03_18705 SH03_RS18695 3788196 3789398 - 2-octaprenylphenol hydroxylase gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18695 SH03_RS18700 SH03_18710 SH03_RS18700 3789421 3790599 - 2-octaprenyl-6-methoxyphenol hydroxylase Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1%2C4-benzoquinone gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18700 SH03_RS18705 SH03_18715 SH03_RS18705 3790596 3791921 - Xaa-Pro aminopeptidase exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue%3B substrate can be as short as a dipeptide gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18705 SH03_RS18710 SH03_18720 SH03_RS18710 3791947 3792531 - hypothetical protein the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers%3B function unknown gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18710 SH03_RS18715 SH03_18725 SH03_RS18715 3792693 3793022 + cell division protein ZapA gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18715 SH03_RS18720 SH03_18730 SH03_RS18720 3793268 3793870 + 5-formyltetrahydrofolate cyclo-ligase ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms%3B unknown function gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18720 SH03_RS18725 SH03_18735 SH03_RS18725 3794259 3795491 - D-3-phosphoglycerate dehydrogenase catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis%3B can also reduce alpha ketoglutarate to form 2-hydroxyglutarate gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18725 SH03_RS18730 SH03_18740 SH03_RS18730 3795747 3796406 - ribose-5-phosphate isomerase A catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18730 SH03_RS18735 SH03_18745 SH03_RS18735 3796462 3796692 - hypothetical protein gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18735 SH03_RS18740 SH03_18750 SH03_RS18740 3796834 3797727 + chromosome initiation inhibitor specific inhibitor of chromosomal initiation of replication in vitro%3B binds the three 13-mers in the origin (oriC) to block initiation of replication%3B also controls genes involved in arginine transport gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18740 SH03_RS18745 SH03_18755 SH03_RS18745 3797931 3800075 + methylmalonyl-CoA mutase gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18745 SH03_RS18750 SH03_18760 SH03_RS18750 3800068 3801063 + GTPase ArgK gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18750 SH03_RS18755 SH03_18765 SH03_RS18755 3801074 3801859 + methylmalonyl-CoA decarboxylase catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18755 SH03_RS18760 SH03_18770 SH03_RS18760 3801883 3803361 + propionyl-CoA--succinate CoA transferase gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18760 SH03_RS18765 SH03_18775 SH03_RS18765 3803358 3804254 - transcriptional regulator gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18765 SH03_RS18770 SH03_18780 SH03_RS18770 3804421 3805161 - oxidative stress defense protein gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18770 SH03_RS18775 SH03_18785 SH03_RS18775 3805254 3805847 - arginine exporter protein Involved in the export of arginine gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18775 SH03_RS18780 SH03_18790 SH03_RS18780 3806028 3806888 - small-conductance mechanosensitive channel participates in the regulation of osmotic pressure changes within the cel gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18780 SH03_RS18785 SH03_18795 SH03_RS18785 3807246 3808325 - fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18785 SH03_RS18790 SH03_18800 SH03_RS18790 3808540 3809703 - phosphoglycerate kinase gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18790 SH03_RS18795 SH03_18805 gapA gapA 3809753 3810772 - D-erythrose-4-phosphate dehydrogenase required for glycolysis%3B catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18795 SH03_RS18800 SH03_18810 SH03_RS18800 3811057 3811770 - PanK family P-loop kinase gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18800 SH03_RS18805 SH03_18815 SH03_RS18805 3811767 3812276 - MtlR family transcriptional regulator gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18805 SH03_RS18810 SH03_18820 SH03_RS18810 3812298 3813263 - fructose 1%2C6-bisphosphatase gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18810 SH03_RS18815 SH03_18825 SH03_RS18815 3813260 3814537 - Zn-binding dehydrogenase gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18815 SH03_RS18820 SH03_18830 SH03_RS18820 3814552 3815940 - PTS mannitol cryptic EIICB component CmtA with CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system%2C which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli%3B cytoplasmic protein gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18820 SH03_RS18825 SH03_18835 cmtB cmtB 3815968 3816411 - mannitol-specific cryptic phosphotransferase enzyme IIA component TolM%3B with CmtA (IIBC)%2C CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system%2C which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli%3B cytoplasmic protein gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18825 SH03_RS18830 SH03_18840 SH03_RS18830 3816725 3818716 - transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18830 SH03_RS18835 SH03_18845 SH03_RS18835 3818994 3819752 + metalloprotease LoiP gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18835 SH03_RS18840 SH03_18850 SH03_RS18840 3819958 3820878 - agmatinase catalyzes the formation of putrescine from agmatine gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18840 SH03_RS18845 SH03_18855 SH03_RS18845 3821016 3822992 - biosynthetic arginine decarboxylase catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18845 SH03_RS18850 SH03_18860 SH03_RS18850 3823001 3823132 - hypothetical protein gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18850 SH03_RS18855 SH03_18865 SH03_RS18855 3823268 3823483 + hypothetical protein gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18855 SH03_RS18860 SH03_18870 SH03_RS18860 3823480 3823731 - membrane protein gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18860 SH03_RS18865 SH03_18875 SH03_RS18865 3823787 3824941 + S-adenosylmethionine synthase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18865 SH03_RS18870 SH03_RS18870 SH03_RS18870 3825365 3826759 + D-galactose transporter GalP gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18870 SH03_RS18875 SH03_18885 SH03_RS18875 3826836 3827333 + protein SprT gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18875 SH03_RS18880 SH03_18890 SH03_RS18880 3827428 3828135 + endonuclease-1 gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18880 SH03_RS18885 SH03_18895 SH03_RS18885 3828215 3828946 + ribosomal RNA small subunit methyltransferase E in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA%3B cells lacking this function can grow%2C but are outcompeted by wild-type%3B SAM-dependent m(3)U1498 methyltransferase gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18885 SH03_RS18890 SH03_18900 SH03_RS18890 3828959 3829909 + glutathione synthetase catalyzes the second step in the glutathione biosynthesis pathway%2C where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine %3D ADP + phosphate + glutathione gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18890 SH03_RS18895 SH03_18905 SH03_RS18895 3830018 3830581 + hypothetical protein gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18895 SH03_RS18900 SH03_18910 SH03_RS18900 3830581 3830997 + Holliday junction DNA helicase similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18900 SH03_RS18905 SH03_18915 SH03_RS18905 3831181 3832161 - PilT family AAA+ ATPase gene gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18905 SH03_RS18910 SH03_18920 SH03_RS18910 3832179 3832883 + YggS family pyridoxal phosphate enzyme gene gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18910 SH03_RS18915 SH03_18925 SH03_RS18915 3832901 3833467 + hypothetical protein gene gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18915 SH03_RS18920 SH03_18930 SH03_RS18920 3833464 3833754 + hypothetical protein gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18920 SH03_RS18925 SH03_18935 SH03_RS18925 3833762 3834355 + non-canonical purine NTP pyrophosphatase HAM1-like protein%3B Rec-dependent growth%3B RgdB%3B yggV%3B it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18925 SH03_RS18930 SH03_18940 SH03_RS18930 3834348 3835484 + coproporphyrinogen III oxidase gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18930 SH03_RS18935 SH03_18945 SH03_RS18935 3835639 3836646 - DUF1202 domain-containing protein gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18935 SH03_RS18940 SH03_18950 ansB ansB 3836763 3837809 - L-asparaginase 2 catalyzes the formation of aspartate from asparagine%2C periplasmic%3B regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18940 SH03_RS18945 SH03_18955 SH03_RS18945 3837985 3838704 - hypothetical protein gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18945 SH03_RS18950 SH03_18960 SH03_RS18950 3838725 3838865 - hypothetical protein gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18950 SH03_RS18955 SH03_18965 SH03_RS18955 3838888 3839214 - hypothetical protein gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18955 SH03_RS18960 SH03_18970 trmB trmB 3839214 3839933 - tRNA (guanine-N(7)-)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase%3B catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18960 SH03_RS18965 SH03_18975 SH03_RS18965 3840094 3841146 + A/G-specific adenine glycosylase gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18965 SH03_RS18970 SH03_18980 SH03_RS18970 3841174 3841449 + Fe(2+)-trafficking protein protects iron-sulfur proteins against oxidative damage gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18970 SH03_RS18975 SH03_18985 mltC mltC 3841514 3842593 + murein transglycosylase Murein hydrolase C%3B membrane-bound%3B lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18975 SH03_RS18980 SH03_18990 SH03_RS18980 3842795 3844051 + nucleoside permease NupG gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18980 SH03_RS18985 SH03_18995 SH03_RS18985 3844101 3846236 - ornithine decarboxylase gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18985 SH03_RS18990 SH03_19000 SH03_RS18990 3846634 3847341 + DUF554 domain-containing protein gene gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18990 SH03_RS18995 SH03_19005 SH03_RS18995 3847447 3847522 + tRNA-Phe tRNA gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS18995 SH03_RS19000 SH03_19010 SH03_RS19000 3847671 3848207 - membrane-anchored secretion pathway M-type protein gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19000 SH03_RS19005 SH03_19015 SH03_RS19005 3848209 3849069 - type II secretion system protein GspL gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19005 SH03_RS19010 SH03_19020 SH03_RS19010 3849135 3850130 - type II secretion system protein GspC part of the general (type II) secretion pathway (GSP)%2C a signal sequence-dependent process responsible for protein export%3B involved in trans-location of exoproteins from the cytoplasm to the periplasm gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19010 SH03_RS19015 SH03_19025 SH03_RS19015 3850148 3850558 - secretin (GspDbeta) OM localization lipoprotein pilotin gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19015 SH03_RS19020 SH03_19030 SH03_RS19020 3850624 3851433 - leader peptidase PppA gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19020 SH03_RS19025 SH03_19035 SH03_RS19025 3851631 3856193 - and surface-associated lipoprotein mucinase gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19025 SH03_RS19030 SH03_19040 SH03_RS19030 3856344 3856526 + hypothetical protein gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19030 SH03_RS19035 SH03_19045 SH03_RS19035 3856678 3858360 - glycolate permease GlcA gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19035 SH03_RS19040 SH03_19050 SH03_RS19040 3858715 3860886 - malate synthase G gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19040 SH03_RS19045 SH03_19055 SH03_RS19045 3860908 3861312 - protein GlcG gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19045 SH03_RS19050 SH03_19060 glcF glcF 3861317 3862540 - glycolate oxidase gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19050 SH03_RS19055 SH03_19065 glcE glcE 3862551 3863603 - glycolate oxidase gene gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19055 SH03_RS19060 SH03_19070 SH03_RS19060 3863603 3865102 - glycolate oxidase gene gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19060 SH03_RS19065 SH03_19075 SH03_RS19065 3865353 3866117 + glc operon transcriptional activator gene gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19065 SH03_RS19070 SH03_19080 SH03_RS19070 3866124 3867260 - DNA-binding protein gene gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19070 SH03_RS19075 SH03_19085 SH03_RS19075 3867295 3868275 + transposase gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19075 SH03_RS19080 SH03_19090 SH03_RS19080 3868422 3869489 - hypothetical protein gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19080 SH03_RS19085 SH03_19095 SH03_RS19085 3869535 3870293 - ATP-binding protein gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19085 SH03_RS19090 SH03_19100 SH03_RS19090 3870325 3871023 - hypothetical protein gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19090 SH03_RS19095 SH03_19105 SH03_RS19095 3871212 3871904 + ATP-binding protein gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19095 SH03_RS19100 SH03_19110 SH03_RS19100 3871953 3873452 - low-affinity inorganic phosphate transporter 2 involved in the transport of inorganic phosphate gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19100 SH03_RS19105 SH03_19115 SH03_RS19105 3873744 3875603 - bifunctional glutathionylspermidine synthetase/amidase catalyzes the formation of glutathionylspermidine from glutathione and spermidine%3B also catalyzes the reverse reaction gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19105 SH03_RS19110 SH03_19120 SH03_RS19110 3875808 3876674 + disulfide-bond oxidoreductase YghU YghU%3B B2989%3B one of eight putative glutathione transferase proteins from E. coli gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19110 SH03_RS19115 SH03_19125 SH03_RS19115 3876797 3877045 - hydrogenase-2 operon protein HybG gene gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19115 SH03_RS19120 SH03_19130 hypA hypA 3877058 3877399 - hydrogenase nickel incorporation protein plays a role in hydrogenase nickel cofactor insertion gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19120 SH03_RS19125 SH03_19135 SH03_RS19125 3877392 3877880 - hydrogenase-2 operon protein HybE gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19125 SH03_RS19130 SH03_19140 hybD hybD 3877873 3878367 - hydrogenase 2 maturation protease protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19130 SH03_RS19135 SH03_19145 SH03_RS19135 3878367 3880070 - hydrogenase-2 large chain involved in hydrogen uptake gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19135 SH03_RS19140 SH03_19150 SH03_RS19140 3880067 3881245 - Ni/Fe-hydrogenase b-type cytochrome subunit HybB%3B cytochrome b subunit of the hydrogenase 2 enzyme%2C composed of HybA%2C B%2C C%2C and O subunits gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19140 SH03_RS19145 SH03_19155 SH03_RS19145 3881235 3882221 - hydrogenase-2 operon protein HybA Fe-S ferrodoxin type component%3B participates in the periplasmic electron-transferring activity of hydrogenase 2 gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19145 SH03_RS19150 SH03_19160 SH03_RS19150 3882224 3883342 - hydrogenase-2 small chain involved in hydrogen uptake gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19150 SH03_RS19155 SH03_19165 SH03_RS19155 3883349 3883534 - hypothetical protein gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19155 SH03_RS19160 SH03_19170 SH03_RS19160 3883531 3883818 - hypothetical protein gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19160 SH03_RS19165 SH03_RS19165 SH03_RS19165 3883937 3884821 - dienelactone hydrolase gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19165 SH03_RS19170 SH03_19180 SH03_RS19170 3884978 3886018 + glyceraldehyde 3-phosphate reductase gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19170 SH03_RS19175 SH03_19185 SH03_RS19175 3886058 3886552 - hypothetical protein gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19175 SH03_RS19180 SH03_19190 SH03_RS19180 3886743 3887627 + oxidoreductase gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19180 SH03_RS19185 SH03_19195 SH03_RS19185 3887899 3888324 - biopolymer transporter ExbD membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19185 SH03_RS19190 SH03_19200 SH03_RS19190 3888331 3889065 - biopolymer transporter ExbB membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19190 SH03_RS19195 SH03_19205 SH03_RS19195 3889058 3889195 - membrane protein gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19195 SH03_RS19200 SH03_19210 SH03_RS19200 3889317 3890504 + cystathionine beta-lyase MetC catalyzes the formation of L-homocysteine from cystathionine gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19200 SH03_RS19205 SH03_19215 SH03_RS19205 3890644 3891303 + hypothetical protein gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19205 SH03_RS19210 SH03_19220 SH03_RS19210 3891343 3892242 - AraC family transcriptional regulator gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19210 SH03_RS19215 SH03_19225 SH03_RS19215 3892239 3892385 - hypothetical protein gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19215 SH03_RS19220 SH03_19230 SH03_RS19220 3892436 3893599 + alcohol dehydrogenase gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19220 SH03_RS19225 SH03_19235 dkgA dkgA 3893704 3894531 + 2%2C5-diketo-D-gluconic acid reductase A methylglyoxal reductase/beta-keto ester reductase%3B catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid%3B also catalyzes the reduction of methylglyoxal%2C ethyl-2-methylacetoacetate and ethyl-acetoacetate gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19225 SH03_RS19230 SH03_19240 SH03_RS19230 3894731 3895657 + DUF3828 domain-containing protein gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19230 SH03_RS19235 SH03_19245 SH03_RS19235 3895708 3895965 + hypothetical protein gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19235 SH03_RS19240 SH03_19250 SH03_RS19240 3896008 3898227 - Radical SAM superfamily protein gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19240 SH03_RS19245 SH03_19255 SH03_RS19245 3898338 3899750 - cell division protein FtsI septal ring component that protects the divisome from stress gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19245 SH03_RS19250 SH03_19260 SH03_RS19250 3899825 3900562 - 1-acyl-sn-glycerol-3-phosphate acyltransferase catalyzes the formation of 1%2C2-diacyl-sn-glycerol 3-phosphate from 1-acyl-sn-glycerol 3-phosphate using either acyl-CoA or acyl-ACP gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19250 SH03_RS19255 SH03_19265 SH03_RS19255 3900796 3903054 - DNA topoisomerase 4 subunit A decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19255 SH03_RS19260 SH03_19270 SH03_RS19260 3903192 3904799 - ABC transporter permease gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19260 SH03_RS19265 SH03_19275 SH03_RS19265 3904932 3905327 - antitoxin gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19265 SH03_RS19270 SH03_19280 SH03_RS19270 3905329 3905625 - mRNA interferase MqsR gene gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19270 SH03_RS19275 SH03_19285 SH03_RS19275 3905830 3906312 - transcriptional regulator gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19275 SH03_RS19280 SH03_19290 SH03_RS19280 3906365 3906757 - hypothetical protein gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19280 SH03_RS19285 SH03_19295 SH03_RS19285 3906909 3907568 + two-component system response regulator response regulator in two-component regulatory system with QseC%3B regulates FlhCD which is the master regulator for flagella and motility genes gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19285 SH03_RS19290 SH03_19300 SH03_RS19290 3907565 3908914 + two-component system sensor histidine kinase gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19290 SH03_RS19295 SH03_19305 SH03_RS19295 3908960 3909292 - hypothetical protein gene gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19295 SH03_RS19300 SH03_19310 SH03_RS19300 3909611 3910192 + modulator of drug activity B involved in drug resistance gene gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19300 SH03_RS19305 SH03_19315 SH03_RS19305 3910223 3910537 + quinol monooxygenase YgiN catalyzes the oxidation of menadiol to menadione gene gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19305 SH03_RS19310 SH03_19320 SH03_RS19310 3910585 3912477 - DNA topoisomerase 4 subunit B decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19310 SH03_RS19315 SH03_19325 SH03_RS19315 3912506 3913087 - esterase Displays esterase activity toward palmitoyl-CoA and pNP-butyrate gene gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19315 SH03_RS19320 SH03_19330 SH03_RS19320 3913087 3913914 - 3'%2C5'-cyclic adenosine monophosphate phosphodiesterase CpdA gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19320 SH03_RS19325 SH03_19335 SH03_RS19325 3913939 3914361 - dehydrogenase gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19325 SH03_RS19330 SH03_19340 nudF nudF 3914362 3914991 - ADP-ribose pyrophosphatase ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19330 SH03_RS19335 SH03_19345 tolC tolC 3915196 3916677 + outer membrane protein TolC trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules%3B functions with a number of efflux systems in the inner membrane to transport molecules out of the cell gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19335 SH03_RS19340 SH03_19350 SH03_RS19340 3916677 3916937 + hypothetical protein gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19340 SH03_RS19345 SH03_19355 SH03_RS19345 3916825 3917496 + membrane protein gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19345 SH03_RS19350 SH03_19360 SH03_RS19350 3917502 3918662 + ATP-Grasp family ATPase gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19350 SH03_RS19355 SH03_19365 SH03_RS19355 3918700 3919488 - 4%2C5- DOPA-extradiol-dioxygenase seems to be involved in biofilm formation%3B in asymptomatic bacteriuria E. coli strains 83972 and VR50%2C the ygiD gene is upregulated during biofilm formation in urine gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19355 SH03_RS19360 SH03_19370 SH03_RS19360 3919631 3920404 + zinc transporter ZupT gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19360 SH03_RS19365 SH03_19375 SH03_RS19365 3920462 3920632 - hypothetical protein gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19365 SH03_RS19370 SH03_19380 ribB ribB 3920894 3921547 - 3%2C4-dihydroxy-2-butanone 4-phosphate synthase DHBP synthase%3B functions during riboflavin biosynthesis gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19370 SH03_RS19375 SH03_19385 SH03_RS19375 3921921 3922211 + BMFP family fusogenic protein gene gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19375 SH03_RS19380 SH03_19390 SH03_RS19380 3922495 3923046 + fimbrial-like adhesin protein gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19380 SH03_RS19385 SH03_19395 SH03_RS19385 3923268 3923633 + transposase represses IS2 gene transcription gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19385 SH03_RS19390 SH03_19400 SH03_RS19390 3923591 3924496 + integrase gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19390 SH03_RS19395 SH03_19405 SH03_RS19395 3924481 3926946 + fimbrial outer membrane usher protein StdB gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19395 SH03_RS19400 SH03_19410 SH03_RS19400 3926962 3927711 + periplasmic pilin chaperone gene gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19400 SH03_RS19405 SH03_19415 SH03_RS19405 3927713 3928777 + fimbrial protein gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19405 SH03_RS19410 SH03_19420 SH03_RS19410 3928820 3929020 - glycogen synthase Involved in glycogen synthesis. May be involved in glycogen priming gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19410 SH03_RS19415 SH03_19425 SH03_RS19415 3929289 3929918 + hypothetical protein gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19415 SH03_RS19420 SH03_19430 SH03_RS19420 3929945 3931606 + hypothetical protein gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19420 SH03_RS19425 SH03_RS19425 SH03_RS19425 3931707 3931959 + hypothetical protein gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19425 SH03_RS19430 SH03_RS19430 SH03_RS19430 3931943 3932334 + hypothetical protein gene gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19430 SH03_RS19435 SH03_19445 SH03_RS19435 3932401 3933834 - bifunctional protein HldE catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D%2CD-heptose-1%2C7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D%2CD-heptose gene gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19435 SH03_RS19440 SH03_19450 SH03_RS19440 3933882 3936722 - glutamate--ammonia-ligase adenylyltransferase catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase%3B also catalyzes the reverse reaction - deadenylation%3B adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme gene gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19440 SH03_RS19445 SH03_19455 SH03_RS19445 3936745 3938046 - inorganic triphosphatase gene gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19445 SH03_RS19450 SH03_19460 SH03_RS19450 3938063 3938248 - hypothetical protein gene gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19450 SH03_RS19455 SH03_19465 SH03_RS19455 3938288 3938908 + signal transduction protein gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19455 SH03_RS19460 SH03_19470 SH03_RS19460 3938972 3940210 + multifunctional CCA protein gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19460 SH03_RS19465 SH03_19475 SH03_RS19465 3940391 3941212 - undecaprenyl-diphosphatase BacA%3B phosphatase activity in Escherichia coli not kinase%3B involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19465 SH03_RS19470 SH03_19480 folB folB 3941302 3941670 - dihydroneopterin aldolase catalyzes the conversion of 7%2C8-dihydroneopterin to 6-hydroxymethyl-7%2C8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin gene gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19470 SH03_RS19475 SH03_19485 SH03_RS19475 3941775 3942392 + glycerol-3-phosphate acyltransferase involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis%3B functions with PlsX gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19475 SH03_RS19480 SH03_19490 SH03_RS19480 3942405 3943337 - transcriptional activator TtdR gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19480 SH03_RS19485 SH03_19495 SH03_RS19485 3943547 3944455 + tartrate dehydratase subunit alpha Involved in the tartrate degradation pathway gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19485 SH03_RS19490 SH03_RS19490 SH03_RS19490 3944452 3945056 + tartrate dehydratase subunit beta Involved in the tartrate degradation pathway gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19490 SH03_RS19495 SH03_19505 SH03_RS19495 3945104 3946567 + L-tartrate/succinate antiporter involved in the transport of citrate into the cell along with the export of succinate out of the cell gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19495 SH03_RS19500 SH03_19510 SH03_RS19500 3946610 3947623 - tRNA N6-adenosine threonylcarbamoyltransferase universal genome maintenance protein%3B Kae1/Qri7/OSGEP/YgjD family protein%3B in Archaea%2C some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex%3B kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32)%3B in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32%3B the protein is essential in Escherichia coli and Bacillus subtilis gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19500 SH03_RS19505 SH03_19515 rpsU rpsU 3947861 3948076 + 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19505 SH03_RS19510 SH03_19520 dnaG dnaG 3948187 3949932 + DNA primase synthesizes RNA primers at the replication forks gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19510 SH03_RS19515 SH03_19525 SH03_RS19515 3950127 3951968 + RNA polymerase sigma factor RpoD sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this is the primary sigma factor of bacteria gene gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19515 SH03_RS19520 SH03_19530 SH03_RS19520 3952047 3952553 - G/U mismatch DNA glycosylase gene gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19520 SH03_RS19525 SH03_19535 SH03_RS19525 3952678 3952753 + tRNA-Met tRNA gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19525 SH03_RS19530 SH03_19540 SH03_RS19530 3952807 3953571 - NADPH-dependent ferric-chelate reductase gene gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19530 SH03_RS19535 SH03_19545 SH03_RS19535 3953859 3954482 + transcriptional regulator gene gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19535 SH03_RS19540 SH03_19550 SH03_RS19540 3954636 3956156 - aerotaxis receptor gene gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19540 SH03_RS19545 SH03_19555 SH03_RS19545 3956574 3957953 + putrescine aminotransferase catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate gene gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19545 SH03_RS19550 SH03_19560 SH03_RS19550 3957995 3958327 - tRNA-binding protein gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19550 SH03_RS19555 SH03_19565 SH03_RS19555 3958546 3959529 + transcriptional regulator gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19555 SH03_RS19560 SH03_19570 ebgA ebgA 3959713 3962805 + evolved beta-galactosidase subunit alpha in Escherichia coli this is the second beta-galactosidase system gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19560 SH03_RS19565 SH03_19575 ebgC ebgC 3962802 3963251 + evolved beta-galactosidase subunit beta in Escherichia coli this is the second beta-galactosidase system gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19565 SH03_RS19570 SH03_19580 SH03_RS19570 3963314 3964747 + inner membrane transporter YgjI gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19570 SH03_RS19575 SH03_19585 SH03_RS19575 3964881 3965951 + periplasmic protein gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19575 SH03_RS19580 SH03_19590 SH03_RS19580 3965968 3968319 + glucosidase YgjK gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19580 SH03_RS19585 SH03_19595 SH03_RS19585 3968745 3970763 + 2%2C4-dienoyl-CoA reductase [NADPH] gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19585 SH03_RS19590 SH03_19600 SH03_RS19590 3970808 3971224 - antitoxin HigA gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19590 SH03_RS19595 SH03_19605 SH03_RS19595 3971221 3971535 - mRNA interferase HigB gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19595 SH03_RS19600 SH03_19610 SH03_RS19600 3971477 3971716 - toxin RelE gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19600 SH03_RS19605 SH03_19615 SH03_RS19605 3971819 3972955 - ribosomal RNA large subunit methyltransferase G gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19605 SH03_RS19610 SH03_19620 SH03_RS19610 3973040 3973543 + metal dependent hydrolase gene gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19610 SH03_RS19615 SH03_19625 SH03_RS19615 3973620 3974312 + DUF218 domain-containing protein gene gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19615 SH03_RS19620 SH03_19630 SH03_RS19620 3974391 3975377 + NAD(P)-dependent dehydrogenase gene gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19620 SH03_RS19625 SH03_19635 SH03_RS19625 3975660 3976625 + hypothetical protein gene gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19625 SH03_RS19630 SH03_19640 SH03_RS19630 3977024 3978268 + serine/threonine transporter SstT involved in the import of serine and threonine coupled with the import of sodium gene gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19630 SH03_RS19635 SH03_19645 SH03_RS19635 3978273 3978824 - hypothetical protein gene gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19635 SH03_RS19640 SH03_19650 SH03_RS19640 3978907 3980394 - altronate dehydratase gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19640 SH03_RS19645 SH03_19655 SH03_RS19645 3980409 3981821 - uronate isomerase catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate%3B functions in glucuronic and galacturonic metabolism gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19645 SH03_RS19650 SH03_19660 SH03_RS19650 3982304 3983602 + hexuronate transporter involved in the transport of aldohexuronates gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19650 SH03_RS19655 SH03_19665 SH03_RS19655 3983732 3984508 + exu regulon transcriptional regulator regulates the expression of uxuBA gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19655 SH03_RS19660 SH03_19670 SH03_RS19660 3984853 3985515 + hypothetical protein gene gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19660 SH03_RS19665 SH03_19675 SH03_RS19665 3985519 3985902 + modulator protein MzrA gene gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19665 SH03_RS19670 SH03_19680 SH03_RS19670 3986049 3986417 + hypothetical protein gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19670 SH03_RS19675 SH03_19685 SH03_RS19675 3986455 3986760 + hypothetical protein gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19675 SH03_RS19680 SH03_19690 SH03_RS19680 3986763 3987167 + hypothetical protein gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19680 SH03_RS19685 SH03_19695 SH03_RS19685 3987157 3987456 + hypothetical protein gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19685 SH03_RS19690 SH03_19700 SH03_RS19690 3987642 3988034 + hypothetical protein gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19690 SH03_RS19695 SH03_19705 SH03_RS19695 3988104 3989090 + glutathionyl-hydroquinone reductase YqjG gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19695 SH03_RS19700 SH03_19710 SH03_RS19700 3989384 3989749 + hypothetical protein gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19700 SH03_RS19705 SH03_19715 SH03_RS19705 3989991 3990347 + hypothetical protein gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19705 SH03_RS19710 SH03_19720 SH03_RS19710 3990398 3991294 - LysR family transcriptional regulator gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19710 SH03_RS19715 SH03_19725 SH03_RS19715 3991399 3992100 + pirin-like protein YhaK gene gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19715 SH03_RS19720 SH03_19730 SH03_RS19720 3992120 3992287 + hypothetical protein gene gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19720 SH03_RS19725 SH03_19735 SH03_RS19725 3992421 3993731 - L-serine dehydratase alpha chain gene gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19725 SH03_RS19730 SH03_19740 SH03_RS19730 3993759 3995090 - transporter gene gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19730 SH03_RS19735 SH03_19745 SH03_RS19735 3995365 3996729 - L-serine dehydratase TdcG catalyzes the formation of pyruvate from serine gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19735 SH03_RS19740 SH03_19750 SH03_RS19740 3996801 3997190 - reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19740 SH03_RS19745 SH03_19755 SH03_RS19745 3997204 3999498 - PFL-like enzyme TdcE formate acetyltransferase%3B catalyzes the formation of formate and acetyl-CoA from pyruvate gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19745 SH03_RS19755 SH03_19765 SH03_RS19755 4000080 4001060 - transposase gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19755 SH03_RS19760 SH03_RS19760 SH03_RS19760 4001127 4001939 - propionate kinase catalyzes the formation of propanoyl phosphate from propanoate and ATP%3B TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19760 SH03_RS19765 SH03_19775 SH03_RS19765 4001965 4003296 - threonine/serine transporter TdcC gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19765 SH03_RS19770 SH03_19780 SH03_RS19770 4003318 4004307 - L-threonine dehydratase catabolic TdcB catalyzes the formation of 2-oxobutanoate from L-threonine%3B catabolic gene gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19770 SH03_RS19775 SH03_19785 SH03_RS19775 4004406 4005344 - transcriptional regulator regulates the tdcABCDEFG operon which is involved in amino acid degradation gene gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19775 SH03_RS19780 SH03_19790 SH03_RS19780 4005533 4005877 + transcriptional regulator participates in controlling the expression of several structural genes for the enzyme threonine dehydratase%3B TdcR activates the tdcABCDEFG operon gene gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19780 SH03_RS19785 SH03_19795 SH03_RS19785 4006133 4006672 + hypothetical protein gene gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19785 SH03_RS19790 SH03_19800 SH03_RS19790 4006694 4007881 + pentapetide repeats-related protein gene gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19790 SH03_RS19795 SH03_19805 SH03_RS19795 4008904 4010049 - glycerate 2-kinase gene gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19795 SH03_RS19800 SH03_19810 garR garR 4010146 4011036 - 2-hydroxy-3-oxopropionate reductase catalyzes the reduction of tartronate semialdehyde to glycerate gene gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19800 SH03_RS19805 SH03_19815 SH03_RS19805 4011066 4011836 - 5-keto-4-deoxy-D-glucarate aldolase cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate gene gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19805 SH03_RS19810 SH03_19820 SH03_RS19810 4011852 4013186 - galactarate transporter gene gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19810 SH03_RS19815 SH03_19825 garD garD 4013561 4015132 + D-galactarate dehydratase catalyzes the formation of 5-dehydro-4-deoxy-D-glucarate from D-galactarate gene gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19815 SH03_RS19820 SH03_19830 SH03_RS19820 4015281 4015616 + antitoxin PrlF SohA%3B PrlF%3B involved in protein secretion%3B when overproduced or mutated%2C it induces growth defect and increased export of a reporter protein%3B a PrlF mutation induces the activity of the Lon protease%2C and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation gene gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19820 SH03_RS19825 SH03_19835 SH03_RS19825 4015616 4016080 + toxin YhaV gene gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19825 SH03_RS19830 SH03_19840 SH03_RS19830 4016135 4016944 - DeoR family transcriptional regulator transcriptional repressor for the agaZVWA and agaSYBCDI operons gene gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19830 SH03_RS19835 SH03_19845 SH03_RS19835 4017193 4018473 + tagatose-1%2C6-bisphosphate aldolase with KbaY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1%2C6-bisphosphate%3B subunit Z may act as a chaperone for the Y subunit gene gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19835 SH03_RS19840 SH03_19850 SH03_RS19840 4018496 4018969 + N-acetylgalactosamine-specific phosphotransferase enzyme IIB component 2 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19840 SH03_RS19845 SH03_19855 SH03_RS19845 4018980 4019381 + N-acetylgalactosamine permease IIC protein 2 gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19845 SH03_RS19850 SH03_19860 SH03_RS19850 4019401 4019904 + N-acetylgalactosamine-6-phosphate deacetylase gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19850 SH03_RS19855 SH03_19865 SH03_RS19855 4020255 4021409 + tagatose-6-phosphate ketose isomerase gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19855 SH03_RS19860 SH03_19870 kbaY kbaY 4021422 4022282 + tagatose-1%2C6-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19860 SH03_RS19865 SH03_19875 SH03_RS19865 4022449 4022925 + N-acetylgalactosamine-specific phosphotransferase enzyme IIB component 1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19865 SH03_RS19870 SH03_19880 SH03_RS19870 4022964 4023767 + N-acetylgalactosamine permease IIC component 1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3Bprotein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19870 SH03_RS19875 SH03_19885 SH03_RS19875 4023757 4024548 + N-acetylgalactosamine permease IID component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IID with IIC forms the translocation channel%3B involved in N-acetylgalactosamine transport gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19875 SH03_RS19880 SH03_19890 SH03_RS19880 4024603 4025304 + galactosamine-6-phosphate isomerase gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19880 SH03_RS19885 SH03_19895 SH03_RS19885 4025705 4026289 + fimbrial-like adhesin protein gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19885 SH03_RS19890 SH03_19900 SH03_RS19890 4026369 4027064 + fimbrial chaperone gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19890 SH03_RS19895 SH03_19905 SH03_RS19895 4027093 4029609 + outer membrane usher protein YraJ gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19895 SH03_RS19900 SH03_19910 SH03_RS19900 4029620 4030711 + fimbrial-like adhesin protein gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19900 SH03_RS19905 SH03_19915 SH03_RS19905 4030754 4031614 - ribosomal RNA small subunit methyltransferase I gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19905 SH03_RS19910 SH03_19920 SH03_RS19910 4031679 4033715 + penicillin-binding protein activator LpoA gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19910 SH03_RS19915 SH03_19925 SH03_RS19915 4033673 4034068 + hypothetical protein gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19915 SH03_RS19920 SH03_19930 SH03_RS19920 4034088 4034678 + DnaA initiator-associating protein DiaA Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein gene gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19920 SH03_RS19925 SH03_19935 SH03_RS19925 4034688 4035263 + hypothetical protein gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19925 SH03_RS19930 SH03_19940 SH03_RS19930 4035377 4036417 - permease gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19930 SH03_RS19935 SH03_19945 SH03_RS19935 4036490 4037125 - nucleoside-diphosphate-sugar epimerase gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19935 SH03_RS19940 SH03_19950 SH03_RS19940 4037253 4037771 + hypothetical protein gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19940 SH03_RS19945 SH03_19955 SH03_RS19945 4037751 4038194 - hypothetical protein gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19945 SH03_RS19950 SH03_19960 SH03_RS19950 4038245 4038547 + nuclease superfamily protein gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19950 SH03_RS19955 SH03_19965 SH03_RS19955 4038534 4039037 - N-acetyltransferase gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19955 SH03_RS19960 SH03_19970 SH03_RS19960 4039031 4039555 - SCP-2 sterol transfer family protein gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19960 SH03_RS19965 SH03_19975 SH03_RS19965 4039764 4040759 + U32 peptidase gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19965 SH03_RS19970 SH03_19980 SH03_RS19970 4040768 4041646 + U32 peptidase gene gene3984 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19970 SH03_RS19975 SH03_19985 SH03_RS19975 4041727 4042734 + luciferase-like monooxygenase gene gene3985 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19975 SH03_RS19980 SH03_19990 SH03_RS19980 4042852 4044096 - tryptophan-specific transporter tryptophan transporter of high affinity gene gene3986 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19980 SH03_RS19985 SH03_19995 SH03_RS19985 4044112 4044249 + hypothetical protein gene gene3987 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19985 SH03_RS19990 SH03_20000 SH03_RS19990 4044250 4046139 - DEAD/DEAH box family ATP-dependent RNA helicase participates in the assembly of the large subunit of the ribosome%3B plays a key role in optimal cell growth at low temperature and is required for normal cell division gene gene3988 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19990 SH03_RS19995 SH03_20005 SH03_RS19995 4046319 4047203 - lipoprotein NlpI lipoprotein that appears to be involved in cell division%3B interacts with the periplasmic protease Prc and may be activated by protease processing gene gene3989 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS19995 SH03_RS20000 SH03_20010 SH03_RS20000 4047312 4049447 - polyribonucleotide nucleotidyltransferase gene gene3990 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20000 SH03_RS20005 SH03_20015 SH03_RS20005 4049694 4049963 - 30S ribosomal protein S15 gene gene3991 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20005 SH03_RS20010 SH03_20020 truB truB 4050112 4051056 - tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene3992 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20010 SH03_RS20015 SH03_20025 rbfA rbfA 4051056 4051457 - ribosome-binding factor A associates with free 30S ribosomal subunits%3B essential for efficient processing of 16S rRNA%3B in Escherichia coli rbfA is induced by cold shock gene gene3993 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20015 SH03_RS20020 SH03_20030 infB infB 4051621 4054293 - translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene3994 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20020 SH03_RS20025 SH03_20035 nusA nusA 4054318 4055805 - transcription termination/antitermination protein NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene3995 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20025 SH03_RS20030 SH03_20040 SH03_RS20030 4055833 4056285 - ribosome maturation factor RimP required for the maturation of the 30S ribosomal subunits gene gene3996 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20030 SH03_RS20035 SH03_20045 SH03_RS20035 4056492 4056568 - tRNA-Met tRNA gene3997 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20035 SH03_RS20040 SH03_20050 SH03_RS20040 4056916 4058259 + argininosuccinate synthase catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis gene gene3998 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20040 SH03_RS20045 SH03_20055 SH03_RS20045 4058267 4059784 - phosphate starvation-inducible protein PsiE gene gene3999 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20045 SH03_RS20050 SH03_20060 SH03_RS20050 4060351 4060437 - tRNA-Leu tRNA gene4000 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20050 SH03_RS20055 SH03_20065 secG secG 4060452 4060784 - protein-export membrane protein SecG gene gene4001 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20055 SH03_RS20060 SH03_20070 glmM glmM 4061012 4062349 - phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene4002 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20060 SH03_RS20065 SH03_20075 folP folP 4062342 4063190 - dihydropteroate synthase catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate and 4-aminobenzoate gene gene4003 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20065 SH03_RS20070 SH03_20080 hflB hflB 4063280 4065214 - ATP-dependent zinc metalloprotease FtsH inner membrane metalloprotease%3B may be involved in degradation of aberrant cytoplasmic and membrane proteins gene gene4004 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20070 SH03_RS20075 SH03_20085 rrmJ rrmJ 4065314 4065943 - ribosomal RNA large subunit methyltransferase E Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit gene gene4005 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20075 SH03_RS20080 SH03_20090 SH03_RS20080 4066069 4066362 + RNA-binding protein RNA binding protein found associated to pre-50S subunit of the ribosome%3B putative role in ribosome assembly%3B necessary for optimal growth but not cell viability gene gene4006 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20080 SH03_RS20085 SH03_20095 greA greA 4066518 4066994 - transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene4007 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20085 SH03_RS20090 SH03_20100 SH03_RS20090 4067242 4068675 + D-alanyl-D-alanine carboxypeptidase penicillin binding protein 4%3B penicillin sensitive%3B catalyzes the formation of D-alanine from D-alanyl-D-alanine%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene4008 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20090 SH03_RS20095 SH03_20105 obgE obgE 4068861 4070033 - GTPase CgtA ObgE%3B essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication gene gene4009 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20095 SH03_RS20100 SH03_20110 SH03_RS20100 4070049 4071014 - transporter gene gene4010 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20100 SH03_RS20105 SH03_20115 rpmA rpmA 4071141 4071398 - 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene4011 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20105 SH03_RS20110 SH03_20120 rplU rplU 4071419 4071730 - 50S ribosomal protein L21 gene gene4012 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20110 SH03_RS20115 SH03_20125 SH03_RS20115 4071989 4072960 + octaprenyl-diphosphate synthase gene gene4013 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20115 SH03_RS20120 SH03_20130 SH03_RS20120 4073188 4073466 + sugar fermentation stimulation protein B activator of maltose metabolism genes gene gene4014 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20120 SH03_RS20125 SH03_20135 SH03_RS20125 4073514 4074773 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene4015 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20125 SH03_RS20130 SH03_20140 SH03_RS20130 4074828 4075082 - acid stress protein IbaG gene gene4016 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20130 SH03_RS20135 SH03_20145 SH03_RS20135 4075242 4075535 - phospholipid ABC transporter-binding protein gene gene4017 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20135 SH03_RS20140 SH03_20150 SH03_RS20140 4075535 4076170 - phospholipid-binding protein involved in maintaining outer membrane lipid asymmetry gene gene4018 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20140 SH03_RS20145 SH03_20155 SH03_RS20145 4076189 4076740 - outer membrane lipid asymmetry maintenance protein MlaD gene gene4019 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20145 SH03_RS20150 SH03_20160 SH03_RS20150 4076745 4077527 - phospholipid ABC transporter permease gene gene4020 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20150 SH03_RS20155 SH03_20165 SH03_RS20155 4077535 4078344 - phospholipid import ATP-binding protein ABC transporter maintaining outer membrane lipid asymmetry gene gene4021 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20155 SH03_RS20160 SH03_20170 SH03_RS20160 4078554 4079531 + hypothetical protein YrbG%3B inner membrane protein involved in cell envelope integrity%3B putative sodium ion/calcium ion exchanger%3B in E. coli it is non essential for cell viability%3B member of the YRBG family of cation/Ca2+ exchangers gene gene4022 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20160 SH03_RS20165 SH03_20175 SH03_RS20165 4079545 4080531 + arabinose 5-phosphate isomerase KdsD gene gene4023 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20165 SH03_RS20170 SH03_20180 SH03_RS20170 4080552 4081118 + 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC forms homotetramers%3B catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate%3B functions in lipopolysaccharide biosynthesis gene gene4024 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20170 SH03_RS20175 SH03_20185 SH03_RS20175 4081115 4081690 + LPS export ABC transporter periplasmic protein LptC gene gene4025 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20175 SH03_RS20180 SH03_20190 SH03_RS20180 4081659 4082216 + LPS export system protein LptA LptA%3B periplasmic binding protein part of a putative ABC superfamily of uptake transporters%3B interacts with LptB protein%2C the ATP binding component of the uptake system gene gene4026 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20180 SH03_RS20185 SH03_20195 SH03_RS20185 4082223 4082948 + LPS export ABC transporter ATP-binding protein gene gene4027 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20185 SH03_RS20190 SH03_20200 SH03_RS20190 4082996 4084429 + RNA polymerase sigma-54 factor sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism%3B the rhizobia often have 2 copies of this sigma factor%3B in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation%3B in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions%2C rpoN1 gene was regulated in response to oxygen gene gene4028 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20190 SH03_RS20195 SH03_20205 SH03_RS20195 4084452 4084739 + ribosome hibernation promoting factor YhbH%3B resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase%3B binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization)%3B seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing gene gene4029 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20195 SH03_RS20200 SH03_20210 SH03_RS20200 4084857 4085348 + nitrogen regulatory protein involved in nitrogen metabolism%3B protein IIA is phosphorylated by enzyme I(Ntr) gene gene4030 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20200 SH03_RS20205 SH03_20215 SH03_RS20205 4085394 4086248 + glmZ(sRNA)-inactivating NTPase glucosamine-6-phosphate regulated%3B inactivates the glmS upregulator glmZ gene gene4031 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20205 SH03_RS20210 SH03_20220 SH03_RS20210 4086245 4086517 + phosphocarrier protein NPr gene gene4032 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20210 SH03_RS20215 SH03_20225 SH03_RS20215 4086731 4087363 + hypothetical protein gene gene4033 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20215 SH03_RS20220 SH03_20230 SH03_RS20220 4087631 4088611 - transposase gene gene4034 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20220 SH03_RS20225 SH03_20235 SH03_RS20225 4088610 4088858 + hypothetical protein gene gene4035 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20225 SH03_RS20230 SH03_20240 SH03_RS20230 4088855 4089571 + transcriptional regulator gene gene4036 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20230 SH03_RS20235 SH03_20245 SH03_RS20235 4089756 4090883 + DUF1016 domain-containing protein gene gene4037 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20235 SH03_RS20240 SH03_20250 SH03_RS20240 4090943 4091407 - DUF386 domain-containing protein gene gene4038 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20240 SH03_RS20245 SH03_20255 SH03_RS20245 4091404 4092279 - N-acetylmannosamine kinase catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein gene gene4039 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20245 SH03_RS20250 SH03_20260 SH03_RS20250 4092276 4092965 - N-acetylmannosamine-6-P epimerase Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate gene gene4040 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20250 SH03_RS20255 SH03_20265 SH03_RS20255 4093013 4094503 - sialic acid transporter gene gene4041 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20255 SH03_RS20260 SH03_20270 SH03_RS20260 4094612 4095505 - N-acetylneuraminate lyase catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid gene gene4042 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20260 SH03_RS20265 SH03_20275 SH03_RS20265 4095627 4096418 - transcriptional regulator NanR Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization gene gene4043 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20265 SH03_RS20270 SH03_20280 SH03_RS20270 4096798 4098165 + transporter YhcL%3B uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters%3B probable role in transport of carboxylates across the inner membrane from the periplasm%3B its encoding gene is not essential for growth and is probably cryptic gene gene4044 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20270 SH03_RS20275 SH03_20285 SH03_RS20275 4098208 4098705 - stringent starvation protein B gene gene4045 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20275 SH03_RS20280 SH03_20290 sspA sspA 4098711 4099349 - stringent starvation protein A transcriptional activator%3B required for activation of bacteriophage P1 late promoter%3B induced by starvation gene gene4046 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20280 SH03_RS20285 SH03_20295 SH03_RS20285 4099744 4100136 - 30S ribosomal protein S9 gene gene4047 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20285 SH03_RS20290 SH03_20300 SH03_RS20290 4100152 4100580 - 50S ribosomal protein L13 gene gene4048 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20290 SH03_RS20295 SH03_20305 SH03_RS20295 4100799 4101926 - cell division protein ZapE gene gene4049 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20295 SH03_RS20300 SH03_20310 SH03_RS20300 4102120 4102518 + hypothetical protein gene gene4050 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20300 SH03_RS20305 SH03_20315 SH03_RS20305 4102672 4104039 + periplasmic pH-dependent serine endoprotease DegQ gene gene4051 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20305 SH03_RS20310 SH03_20320 SH03_RS20310 4104129 4105196 + serine endoprotease DegS gene gene4052 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20310 SH03_RS20315 SH03_20325 SH03_RS20315 4105259 4106197 - malate dehydrogenase oxidizes malate to oxaloacetate gene gene4053 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20315 SH03_RS20320 SH03_20330 SH03_RS20320 4106632 4107102 + arginine repressor regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes gene gene4054 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20320 SH03_RS20325 SH03_20335 SH03_RS20325 4107467 4107730 + membrane protein gene gene4055 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20325 SH03_RS20330 SH03_20340 SH03_RS20330 4107786 4108058 - barnase inhibitor gene gene4056 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20330 SH03_RS20335 SH03_20345 SH03_RS20335 4108150 4110117 - p-hydroxybenzoic acid efflux pump subunit AaeB with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene4057 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20335 SH03_RS20340 SH03_20350 SH03_RS20340 4110123 4111055 - p-hydroxybenzoic acid efflux pump subunit AaeA with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid%2C 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene4058 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20340 SH03_RS20345 SH03_20355 SH03_RS20345 4111063 4111266 - protein AaeX membrane protein AaeX%3B the gene is a member of the aaeXAB operon gene gene4059 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20345 SH03_RS20350 SH03_20360 SH03_RS20350 4111449 4112378 + HTH-type transcriptional activator AaeR for aaeXAB operon gene gene4060 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20350 SH03_RS20355 SH03_20365 tldD tldD 4112512 4113957 - protease TldD responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17%2C an exported protein that targets the essential topoisomerase II DNA gyrase%3B degrades the E. coli plasmid F-encoded CcdA gene gene4061 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20355 SH03_RS20360 SH03_20370 SH03_RS20360 4114387 4118187 - hypothetical protein gene gene4062 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20360 SH03_RS20365 SH03_20375 SH03_RS20365 4118255 4119724 - ribonuclease G involved in the processing of the 5'end of 16S rRNA gene gene4063 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20365 SH03_RS20370 SH03_20380 SH03_RS20370 4119714 4120307 - septum formation inhibitor Maf Maf%3B overexpression in Bacillus subtilis inhibits septation in the dividing cell gene gene4064 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20370 SH03_RS20375 SH03_20385 SH03_RS20375 4120316 4120804 - rod shape-determining protein MreD part of cell wall structural complex MreBCD%3B transmembrane component gene gene4065 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20375 SH03_RS20380 SH03_20390 SH03_RS20380 4120804 4121907 - cell shape-determining protein MreC in some organisms this protein is a transmembrane protein while in others it is periplasmic%3B involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall gene gene4066 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20380 SH03_RS20385 SH03_20395 SH03_RS20385 4121973 4123016 - rod shape-determining protein MreB gene gene4067 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20385 SH03_RS20390 SH03_20400 SH03_RS20390 4123124 4123312 + hypothetical protein gene gene4068 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20390 SH03_RS20395 SH03_20405 SH03_RS20395 4123321 4125261 - RNase E specificity factor CsrD regulates the degradation of the small RNAs CsrB and CsrC%3B may function to targate RNase E to specific RNA molecules gene gene4069 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20395 SH03_RS20400 SH03_20410 SH03_RS20400 4125413 4126387 + acrylyl-CoA reductase AcuI gene gene4070 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20400 SH03_RS20405 SH03_20415 SH03_RS20405 4126445 4126546 - hypothetical protein gene gene4071 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20405 SH03_RS20410 SH03_20420 SH03_RS20410 4126673 4126792 + hypothetical protein gene gene4072 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20410 SH03_RS20415 SH03_20425 SH03_RS20415 4126796 4126960 + hypothetical protein gene gene4073 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20415 SH03_RS20420 SH03_20430 SH03_RS20420 4127365 4127835 + acetyl-CoA carboxylase biotin carboxyl carrier protein subunit composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex%2C the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene4074 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20420 SH03_RS20425 SH03_20435 SH03_RS20425 4127846 4129195 + acetyl-CoA carboxylase biotin carboxylase subunit an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene4075 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20425 SH03_RS20430 SH03_20440 SH03_RS20430 4129304 4129546 + DUF997 domain-containing protein gene gene4076 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20430 SH03_RS20435 SH03_20445 panF panF 4129536 4130987 + sodium/pantothenate symporter mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions%3B member of SSS family of sodium/solute symporters%3B the imported panthothenate is phosphorylated by panthothenate kinase gene gene4077 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20435 SH03_RS20440 SH03_20450 prmA prmA 4130999 4131880 + ribosomal protein L11 methyltransferase methylates ribosomal protein L11 at multiple amino acid positions%3B mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype gene gene4078 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20440 SH03_RS20445 SH03_20455 SH03_RS20445 4132209 4133174 + tRNA-dihydrouridine synthase B gene gene4079 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20445 SH03_RS20450 SH03_20460 fis fis 4133200 4133496 + Fis family transcriptional regulator Stimulates excision of phage lambda%3B affects Mu development%3B acts as an activator of rRNA and iRNA transcription gene gene4080 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20450 SH03_RS20455 SH03_20465 SH03_RS20455 4133582 4134466 + DNA adenine methyltransferase YhdJ gene gene4081 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20455 SH03_RS20460 SH03_20470 SH03_RS20460 4134550 4134729 + transporter gene gene4082 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20460 SH03_RS20465 SH03_20475 SH03_RS20465 4134732 4135394 - acrEF/envCD operon repressor gene gene4083 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20465 SH03_RS20470 SH03_20480 SH03_RS20470 4135793 4136950 + MexX family efflux pump subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene4084 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20470 SH03_RS20475 SH03_20485 SH03_RS20475 4136962 4140066 + multidrug efflux RND transporter permease subunit gene gene4085 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20475 SH03_RS20480 SH03_20490 SH03_RS20480 4140319 4140540 + membrane protein gene gene4086 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20480 SH03_RS20485 SH03_20495 SH03_RS20485 4140766 4140942 + hypothetical protein gene gene4087 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20485 SH03_RS20490 SH03_20500 SH03_RS20490 4141078 4141995 + amino acid ABC transporter substrate-binding protein gene gene4088 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20490 SH03_RS20495 SH03_20505 SH03_RS20495 4142063 4143244 + amino acid ABC transporter permease gene gene4089 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20495 SH03_RS20500 SH03_20510 SH03_RS20500 4143254 4144357 + amino acid ABC transporter permease gene gene4090 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20500 SH03_RS20505 SH03_20515 SH03_RS20505 4144365 4145123 + amino acid ABC transporter ATPase gene gene4091 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20505 SH03_RS20510 SH03_20520 SH03_RS20510 4145354 4145469 - 5S ribosomal RNA rRNA gene4092 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20510 SH03_RS20515 SH03_20525 SH03_RS20515 4145509 4145584 - tRNA-Thr tRNA gene4093 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20515 SH03_RS20520 SH03_20530 SH03_RS20520 4145599 4145714 - 5S ribosomal RNA rRNA gene4094 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20520 SH03_RS20525 SH03_20535 SH03_RS20525 4145792 4148721 - 23S ribosomal RNA rRNA gene4095 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20525 SH03_RS20530 SH03_20540 SH03_RS20530 4148887 4148962 - tRNA-Ala tRNA gene4096 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20530 SH03_RS20535 SH03_20545 SH03_RS20535 4149005 4149081 - tRNA-Ile tRNA gene4097 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20535 SH03_RS20540 SH03_20550 SH03_RS20540 4149138 4150693 - 16S ribosomal RNA rRNA gene4098 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20540 SH03_RS20545 SH03_20555 SH03_RS20545 4151165 4151719 + hypothetical protein gene gene4099 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20545 SH03_RS20550 SH03_20560 SH03_RS20550 4151695 4151952 - DUF1488 domain-containing protein gene gene4100 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20550 SH03_RS20555 SH03_20565 SH03_RS20555 4151949 4152767 - shikimate dehydrogenase (NADP+) gene gene4101 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20555 SH03_RS20560 SH03_20570 SH03_RS20560 4152772 4153344 - threonylcarbamoyl-AMP synthase involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs gene gene4102 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20560 SH03_RS20565 SH03_20575 SH03_RS20565 4153349 4153891 - ssDNA-binding protein%2C function unknown gene gene4103 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20565 SH03_RS20570 SH03_20580 SH03_RS20570 4153920 4154393 - protein Smg gene gene4104 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20570 SH03_RS20575 SH03_20585 SH03_RS20575 4154365 4155489 - protein smf gene gene4105 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20575 SH03_RS20580 SH03_20590 SH03_RS20580 4155619 4156128 + peptide deformylase gene gene4106 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20580 SH03_RS20585 SH03_20595 fmt fmt 4156143 4157090 + methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene4107 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20585 SH03_RS20590 SH03_20600 SH03_RS20590 4157136 4158425 + ribosomal RNA small subunit methyltransferase B catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA%3B SAM-dependent methyltransferase gene gene4108 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20590 SH03_RS20595 SH03_20605 trkA trkA 4158447 4159823 + trk system potassium uptake protein trkA involved in potassium uptake%3B found to be peripherally associated with the inner membrane in Escherichia coli%3B contains an NAD-binding domain gene gene4109 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20595 SH03_RS20600 SH03_20610 mscL mscL 4159953 4160363 + large-conductance mechanosensitive channel forms homopentamer%3B channel that opens in response to pressure or hypoosmotic shock gene gene4110 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20600 SH03_RS20605 SH03_20615 SH03_RS20605 4160360 4160578 - ribosome-rescue factor A gene gene4111 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20605 SH03_RS20610 SH03_20620 zntR zntR 4160634 4161059 - transcriptional regulator mediates expression of the zinc export protein ZntA in response to high levels of zinc%3B member of MerR family of transcriptional regulators gene gene4112 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20610 SH03_RS20615 SH03_20625 SH03_RS20615 4161070 4161438 - DUF1992 domain-containing protein gene gene4113 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20615 SH03_RS20620 SH03_20630 rplQ rplQ 4161545 4161928 - 50S ribosomal protein L17 is a component of the macrolide binding site in the peptidyl transferase center gene gene4114 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20620 SH03_RS20625 SH03_20635 SH03_RS20625 4161969 4162958 - DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene4115 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20625 SH03_RS20630 SH03_20640 SH03_RS20630 4162984 4163604 - 30S ribosomal protein S4 gene gene4116 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20630 SH03_RS20635 SH03_20645 SH03_RS20635 4163638 4164027 - 30S ribosomal protein S11 gene gene4117 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20635 SH03_RS20640 SH03_20650 SH03_RS20640 4164044 4164400 - 30S ribosomal protein S13 gene gene4118 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20640 SH03_RS20645 SH03_20655 SH03_RS20645 4164547 4164663 - 50S ribosomal protein L36 gene gene4119 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20645 SH03_RS20650 SH03_20660 secY secY 4164695 4166026 - preprotein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene4120 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20650 SH03_RS20655 SH03_20665 SH03_RS20655 4166034 4166468 - 50S ribosomal protein L15 gene gene4121 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20655 SH03_RS20660 SH03_20670 rpmD rpmD 4166472 4166651 - 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene4122 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20660 SH03_RS20665 SH03_20675 SH03_RS20665 4166655 4167158 - 30S ribosomal protein S5 gene gene4123 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20665 SH03_RS20670 SH03_20680 SH03_RS20670 4167173 4167526 - 50S ribosomal protein L18 gene gene4124 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20670 SH03_RS20675 SH03_20685 SH03_RS20675 4167536 4168069 - 50S ribosomal protein L6 gene gene4125 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20675 SH03_RS20680 SH03_20690 SH03_RS20680 4168082 4168474 - 30S ribosomal protein S8 gene gene4126 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20680 SH03_RS20685 SH03_20695 rpsN rpsN 4168508 4168813 - 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene4127 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20685 SH03_RS20690 SH03_20700 SH03_RS20690 4168828 4169367 - 50S ribosomal protein L5 gene gene4128 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20690 SH03_RS20695 SH03_20705 rplX rplX 4169382 4169696 - 50S ribosomal protein L24 assembly initiator protein%3B binds to 5' end of 23S rRNA and nucleates assembly of the 50S%3B surrounds polypeptide exit tunnel gene gene4129 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20695 SH03_RS20700 SH03_20710 SH03_RS20700 4169707 4170078 - 50S ribosomal protein L14 gene gene4130 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20700 SH03_RS20705 SH03_20715 SH03_RS20705 4170243 4170497 - 30S ribosomal protein S17 gene gene4131 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20705 SH03_RS20710 SH03_20720 SH03_RS20710 4170497 4170688 - 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene4132 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20710 SH03_RS20715 SH03_20725 SH03_RS20715 4170688 4171098 - 50S ribosomal protein L16 gene gene4133 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20715 SH03_RS20720 SH03_20730 SH03_RS20720 4171111 4171812 - 30S ribosomal protein S3 gene gene4134 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20720 SH03_RS20725 SH03_20735 SH03_RS20725 4171830 4172162 - 50S ribosomal protein L22 gene gene4135 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20725 SH03_RS20730 SH03_20740 SH03_RS20730 4172177 4172455 - 30S ribosomal protein S19 gene gene4136 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20730 SH03_RS20735 SH03_20745 SH03_RS20735 4172472 4173293 - 50S ribosomal protein L2 gene gene4137 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20735 SH03_RS20740 SH03_20750 rplW rplW 4173311 4173613 - 50S ribosomal protein L23 binds third domain of 23S rRNA and protein L29%3B part of exit tunnel gene gene4138 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20740 SH03_RS20745 SH03_20755 rplD rplD 4173610 4174215 - 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene4139 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20745 SH03_RS20750 SH03_20760 SH03_RS20750 4174226 4174855 - 50S ribosomal protein L3 gene gene4140 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20750 SH03_RS20755 SH03_20765 rpsJ rpsJ 4174888 4175199 - 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene4141 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20755 SH03_RS20760 SH03_20770 SH03_RS20760 4175437 4175856 - hypothetical protein involved in type II protein secretion gene gene4142 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20760 SH03_RS20765 SH03_20775 SH03_RS20765 4175858 4177327 - general secretory pathway protein gene gene4143 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20765 SH03_RS20770 SH03_20780 SH03_RS20770 4177507 4178322 + type II secretion system protein GspC gene gene4144 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20770 SH03_RS20775 SH03_20785 SH03_RS20775 4178306 4180258 + type II secretion system protein GspD gene gene4145 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20775 SH03_RS20780 SH03_20790 SH03_RS20780 4180268 4181749 + type II secretion system protein GspE gene gene4146 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20780 SH03_RS20785 SH03_20795 SH03_RS20785 4181746 4182942 + type II secretion system protein GspF gene gene4147 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20785 SH03_RS20790 SH03_20800 SH03_RS20790 4182952 4183389 + type II secretion system protein GspG gene gene4148 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20790 SH03_RS20795 SH03_20805 SH03_RS20795 4183397 4183906 + type II secretion system protein GspH gene gene4149 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20795 SH03_RS20800 SH03_20810 SH03_RS20800 4183903 4184280 + type II secretion system protein GspI gene gene4150 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20800 SH03_RS20805 SH03_20815 SH03_RS20805 4184273 4184860 + general secretion pathway protein gene gene4151 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20805 SH03_RS20810 SH03_20820 SH03_RS20810 4184853 4185836 + general secretory pathway protein gene gene4152 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20810 SH03_RS20815 SH03_20825 SH03_RS20815 4185851 4187014 + type II secretion system protein GspL gene gene4153 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20815 SH03_RS20820 SH03_20830 SH03_RS20820 4187011 4187472 + general secretion pathway protein GspM gene gene4154 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20820 SH03_RS20825 SH03_20835 SH03_RS20825 4187472 4188149 + type 4 prepilin-like proteins leader peptide-processing enzyme gene gene4155 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20825 SH03_RS20830 SH03_20840 SH03_RS20830 4188178 4188654 - bacterioferritin iron storage protein gene gene4156 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20830 SH03_RS20835 SH03_20845 SH03_RS20835 4188726 4188920 - bacterioferritin-associated ferredoxin gene gene4157 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20835 SH03_RS20840 SH03_20850 SH03_RS20840 4189089 4191782 - bifunctional chitinase/lysozyme gene gene4158 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20840 SH03_RS20845 SH03_20855 tuf tuf 4192074 4193258 - translation elongation factor EF-Tu 1 EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene4159 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20845 SH03_RS20850 SH03_20860 fusA fusA 4193329 4195443 - elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene4160 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20850 SH03_RS20855 SH03_20865 SH03_RS20855 4195471 4196010 - 30S ribosomal protein S7 gene gene4161 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20855 SH03_RS20860 SH03_20870 SH03_RS20860 4196107 4196481 - 30S ribosomal protein S12 gene gene4162 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20860 SH03_RS20865 SH03_20875 SH03_RS20865 4196607 4196894 - protein TusB in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene4163 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20865 SH03_RS20870 SH03_20880 SH03_RS20870 4196902 4197261 - protein TusC in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur transfer that results in thiouridation to U34 position in some tRNAs gene gene4164 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20870 SH03_RS20875 SH03_20885 SH03_RS20875 4197261 4197647 - sulfurtransferase TusD in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene4165 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20875 SH03_RS20880 SH03_20890 SH03_RS20880 4197647 4198369 - transcriptional regulator gene gene4166 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20880 SH03_RS20885 SH03_20895 SH03_RS20885 4198536 4199348 - FKBP-type peptidyl-prolyl cis-trans isomerase rotamase gene gene4167 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20885 SH03_RS20890 SH03_20900 SH03_RS20890 4199569 4199787 + protein SlyX required for phi X174 lysis gene gene4168 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20890 SH03_RS20895 SH03_20905 SH03_RS20895 4199836 4200426 - FKBP-type peptidyl-prolyl cis-trans isomerase rotamase gene gene4169 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20895 SH03_RS20900 SH03_20910 SH03_RS20900 4200521 4200721 - hypothetical protein gene gene4170 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20900 SH03_RS20905 SH03_20915 SH03_RS20905 4200731 4202536 - glutathione-regulated potassium-efflux system protein KefB involved in potassium efflux gene gene4171 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20905 SH03_RS20910 SH03_20920 SH03_RS20910 4202536 4203087 - potassium transporter required for KefB activity gene gene4172 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20910 SH03_RS20915 SH03_20925 SH03_RS20915 4203218 4205131 + ABC transporter ATP-binding protein gene gene4173 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20915 SH03_RS20920 SH03_20930 SH03_RS20920 4205131 4206153 + UPF0017 family hydrolase gene gene4174 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20920 SH03_RS20925 SH03_20935 SH03_RS20925 4206147 4206365 + hypothetical protein gene gene4175 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20925 SH03_RS20930 SH03_20940 SH03_RS20930 4206419 4207288 + phosphoribulokinase gene gene4176 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20930 SH03_RS20935 SH03_20945 SH03_RS20935 4207343 4207747 - hypothetical protein gene gene4177 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20935 SH03_RS20940 SH03_20950 SH03_RS20940 4207827 4208042 + hypothetical protein gene gene4178 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20940 SH03_RS20945 SH03_20955 SH03_RS20945 4208049 4208681 + cAMP-activated global transcriptional regulator CRP cAMP receptor protein%3B complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons gene gene4179 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20945 SH03_RS20950 SH03_20960 SH03_RS20950 4208732 4210822 + hypothetical protein gene gene4180 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20950 SH03_RS20955 SH03_20965 argD argD 4210889 4212109 - acetylornithine aminotransferase DapATase%3B bifunctional enzyme that functions in arginine and lysine biosynthetic pathways%3B catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2%2C6-diaminoheptanedioate gene gene4181 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20955 SH03_RS20960 SH03_20970 SH03_RS20960 4212195 4212758 - aminodeoxychorismate synthase TrpG%3B with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine%3B TrpG provides the glutamine amidotransferase activity gene gene4182 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20960 SH03_RS20965 SH03_20975 SH03_RS20965 4212790 4213392 - adenosine monophosphate-protein transferase gene gene4183 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20965 SH03_RS20970 SH03_20980 SH03_RS20970 4213382 4213549 - antitoxin gene gene4184 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20970 SH03_RS20975 SH03_20985 SH03_RS20975 4213654 4214226 - peptidyl-prolyl cis-trans isomerase gene gene4185 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20975 SH03_RS20980 SH03_20990 SH03_RS20980 4214497 4215678 + protein TsgA gene gene4186 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20980 SH03_RS20985 SH03_20995 SH03_RS20985 4215940 4218483 + nitrite reductase (NADH) large subunit gene gene4187 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20985 SH03_RS20990 SH03_21000 nirD nirD 4218480 4218806 + nitrite reductase (NADH) small subunit involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+%3B bounds to NirB%2C the cytoplasmic subunit%2C whose expression is induced at high nitrate concentrations gene gene4188 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20990 SH03_RS20995 SH03_21005 SH03_RS20995 4218932 4219738 + nitrite transporter NirC member of the FNT family of formate and nitrite transporters gene gene4189 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS20995 SH03_RS21000 SH03_21010 cysG cysG 4219757 4221130 + siroheme synthase multifunction enzyme consisting of uroporphyrin-III C-methyltransferase%2C precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase%3B catalyzes the methylation of uroporphyrinogen III to form precorrin-2%2C then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin gene gene4190 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21000 SH03_RS21005 SH03_21015 SH03_RS21005 4221377 4221544 + lipoprotein gene gene4191 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21005 SH03_RS21010 SH03_21020 frlA frlA 4221839 4223176 + fructoselysine transporter inner membrane protein possibly involved in fructoselysine transport%3B member of the flr operon gene gene4192 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21010 SH03_RS21015 SH03_21025 frlB frlB 4223197 4224219 + fructoselysine 6-phosphate deglycase catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine gene gene4193 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21015 SH03_RS21020 SH03_21030 SH03_RS21020 4224269 4225099 + protein FrlC YhfOP%3B YhfP%3B YhfO%3B FrlC%3B catalyzes the interconversion of fructoselysine and psicoselysine gene gene4194 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21020 SH03_RS21025 SH03_21035 SH03_RS21025 4225096 4225881 + fructoselysine kinase gene gene4195 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21025 SH03_RS21030 SH03_21040 SH03_RS21030 4225981 4226712 + transcriptional regulator may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM%2C yhfN%2C yhfO%2C yhfP%2C yhfQ%2C and yhfR genes gene gene4196 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21030 SH03_RS21035 SH03_21045 SH03_RS21035 4226864 4227949 - FNR-regulated pyridoxal phosphate-dependent aminotransferase gene gene4197 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21035 SH03_RS21040 SH03_21050 SH03_RS21040 4227961 4229265 - hypothetical protein gene gene4198 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21040 SH03_RS21045 SH03_21055 SH03_RS21045 4229277 4229630 - DUF2620 domain-containing protein gene gene4199 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21045 SH03_RS21050 SH03_21060 SH03_RS21050 4229641 4230519 - phosphotriesterase homology protein phosphotriesterase homology protein%3B PhP%3B YhfV%3B member of a family of proteins related to phosphotriesterase (PTE) gene gene4200 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21050 SH03_RS21055 SH03_21065 SH03_RS21055 4230516 4231742 - phosphopentomutase-related metalloenzyme superfamily protein gene gene4201 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21055 SH03_RS21060 SH03_21070 SH03_RS21060 4231742 4232905 - pyridoxal 5''-phosphate binding protein gene gene4202 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21060 SH03_RS21065 SH03_21075 SH03_RS21065 4232989 4233351 - PRD domain protein gene gene4203 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21065 SH03_RS21070 SH03_21080 SH03_RS21070 4233368 4234273 - transcriptional regulator gene gene4204 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21070 SH03_RS21075 SH03_21085 SH03_RS21075 4234563 4235567 - tryptophan--tRNA ligase gene gene4205 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21075 SH03_RS21080 SH03_21090 SH03_RS21080 4235560 4236318 - phosphoglycolate phosphatase catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate gene gene4206 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21080 SH03_RS21085 SH03_21095 SH03_RS21085 4236311 4236988 - ribulose-phosphate 3-epimerase gene gene4207 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21085 SH03_RS21090 SH03_21100 SH03_RS21090 4237006 4237842 - DNA adenine methylase gene gene4208 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21090 SH03_RS21095 SH03_21105 SH03_RS21095 4237949 4239235 - protein DamX binds the septal ring gene gene4209 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21095 SH03_RS21100 SH03_21110 aroB aroB 4239327 4240415 - 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene4210 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21100 SH03_RS21105 SH03_21115 aroK aroK 4240472 4240993 - shikimate kinase type I enzyme similar to type II but differentially regulated%3B major shikimate kinase in fully repressed cells%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene4211 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21105 SH03_RS21110 SH03_21120 hofQ hofQ 4241394 4242554 - porin outer membrane porin probably involved in uptake of extracellular double-stranded DNA%3B similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa gene gene4212 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21110 SH03_RS21115 SH03_21125 SH03_RS21115 4242544 4242948 - DNA catabolic protein gene gene4213 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21115 SH03_RS21120 SH03_21130 SH03_RS21120 4242938 4243378 - DNA catabolic protein gene gene4214 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21120 SH03_RS21125 SH03_21135 SH03_RS21125 4243362 4243901 - DNA utilization protein HofN gene gene4215 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21125 SH03_RS21130 SH03_21140 SH03_RS21130 4243901 4244680 - DNA catabolic pilus assembly protein gene gene4216 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21130 SH03_RS21135 SH03_21145 mrcA mrcA 4244800 4247352 + penicillin-binding protein 1A bifunctional murein transglycosylase/murein transpeptidase%3B penicillin-binding protein 1A%3B involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation%3B penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits gene gene4217 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21135 SH03_RS21140 SH03_21150 nudE nudE 4247518 4248078 - ADP compounds hydrolase NudE ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene4218 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21140 SH03_RS21145 SH03_21155 SH03_RS21145 4248398 4250533 + RcsCDB-response attenuator%2C inner membrane protein gene gene4219 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21145 SH03_RS21150 SH03_21160 SH03_RS21150 4250598 4251266 + GMP/IMP nucleotidase YrfG gene gene4220 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21150 SH03_RS21155 SH03_21165 SH03_RS21155 4251277 4251678 + heat-shock protein 15 gene gene4221 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21155 SH03_RS21160 SH03_21170 hslO hslO 4251703 4252581 + heat-shock protein Hsp33 becomes active under oxidative stress%3B four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive%3B oxidative stress results in oxidized cysteines%2C release of zinc%2C and binding of Hsp33 to aggregation-prone proteins%3B forms dimers and higher order oligomers gene gene4222 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21160 SH03_RS21165 SH03_21175 SH03_RS21165 4252644 4254368 - DUF4153 domain-containing protein gene gene4223 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21165 SH03_RS21170 SH03_21180 SH03_RS21170 4254444 4254575 - hypothetical protein gene gene4224 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21170 SH03_RS21175 SH03_21185 SH03_RS21175 4254747 4256369 + phosphoenolpyruvate carboxykinase [ATP] PEP carboxykinase%3B PEP carboxylase%3B PEPCK%3B catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP gene gene4225 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21175 SH03_RS21180 SH03_21190 envZ envZ 4256445 4257797 - two-component system sensor histidine kinase membrane-localized osmosensor%3B histidine kinase%3B in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR gene gene4226 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21180 SH03_RS21185 SH03_21195 ompR ompR 4257794 4258513 - two-component system response regulator part of two-component system EnvZ/OmpR%3B regulates transcription of outer membrane porin genes ompC/F%3B under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR%3B the result is increased expression of ompC and repression of ompF%3B also functions in regulation of other genes%3B forms dimers upon phosphorylation gene gene4227 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21185 SH03_RS21190 SH03_21200 greB greB 4258741 4259217 + transcription elongation factor GreB necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene4228 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21190 SH03_RS21195 SH03_21205 SH03_RS21195 4259314 4261635 + hypothetical protein gene gene4229 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21195 SH03_RS21200 SH03_21210 feoA feoA 4262092 4262319 + ferrous iron transporter A gene gene4230 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21200 SH03_RS21205 SH03_21215 feoB feoB 4262336 4264657 + ferrous iron transporter B cytoplasmic membrane ferrous uptake system permease%3B mutations disrupt the ability of Escherichia coli to take up ferrous iron%3B GTP-binding protein which requires GTP for efficient iron(II) uptake gene gene4231 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21205 SH03_RS21210 SH03_21220 SH03_RS21210 4264657 4264893 + ferrous iron transporter C regulatory protein that controls transcription of feoABC genes gene gene4232 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21210 SH03_RS21215 SH03_21225 SH03_RS21215 4265096 4265974 + transposase gene gene4233 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21215 SH03_RS21220 SH03_21230 SH03_RS21220 4266003 4266773 - pimeloyl-[acyl-carrier protein] methyl ester esterase Shows carboxylesterase activity with a preference for short chain fatty acid esters%3B involved in pimeloyl-CoA synthesis gene gene4234 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21220 SH03_RS21225 SH03_21235 SH03_RS21225 4266811 4267494 + protein GntX required for utilization of DNA as the sole source of carbon and energy gene gene4235 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21225 SH03_RS21230 SH03_21240 SH03_RS21230 4267553 4268128 + fe/S biogenesis protein nfuA cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene4236 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21230 SH03_RS21235 SH03_21245 SH03_RS21235 4268488 4269804 + gluconate transporter gene gene4237 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21235 SH03_RS21240 SH03_21250 malQ malQ 4269915 4271999 - 4-alpha-glucanotransferase amylomaltase%3B acts to release glucose from maltodextrins gene gene4238 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21240 SH03_RS21245 SH03_21255 SH03_RS21245 4272009 4274402 - maltodextrin phosphorylase gene gene4239 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21245 SH03_RS21250 SH03_21260 SH03_RS21250 4275014 4277719 + transcriptional regulator Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides gene gene4240 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21250 SH03_RS21255 SH03_21265 SH03_RS21255 4277762 4278778 - RNA 3'-terminal phosphate cyclase catalyzes the conversion of terminal3'-phosphate of RNA to the 2'%2C3'-cyclicphosphodiester gene gene4241 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21255 SH03_RS21260 SH03_21270 SH03_RS21260 4278782 4280008 - RNA-splicing ligase RtcB gene gene4242 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21260 SH03_RS21265 SH03_21275 SH03_RS21265 4280197 4281795 + transcriptional regulator sigma 54-dependent%3B regulates genes involved in forming a 2'%2C3'-cyclic phosphodiester on RNA gene gene4243 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21265 SH03_RS21270 SH03_21280 SH03_RS21270 4281777 4282535 - glycerol-3-phosphate regulon repressor represses the glpD%2C glpFK%2C glpTQ%2C and glpACB operons involved in glycerol-3-phosphate metabolism gene gene4244 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21270 SH03_RS21275 SH03_21285 SH03_RS21275 4282552 4283382 - rhomboid protease GlpG protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity gene gene4245 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21275 SH03_RS21280 SH03_21290 glpE glpE 4283427 4283753 - thiosulfate sulfurtransferase GlpE belongs to rhodanese family%3B thiosulfate thiotransferase%3B in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency%3B contains an active site cysteine gene gene4246 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21280 SH03_RS21285 SH03_21295 glpD glpD 4283943 4285448 + aerobic glycerol-3-phosphate dehydrogenase in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions%3B anaerobic expression is repressed by the arcAB system%3B converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8%3B associates with the cytoplasmic membrane gene gene4247 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21285 SH03_RS21290 SH03_21300 SH03_RS21290 4285654 4285845 - membrane protein gene gene4248 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21290 SH03_RS21295 SH03_21305 SH03_RS21295 4286064 4288511 - glycogen phosphorylase gene gene4249 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21295 SH03_RS21300 SH03_21310 glgA glgA 4288530 4289963 - glycogen synthase catalyzes the formation of alpha-1%2C4-glucan chains from ADP-glucose gene gene4250 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21300 SH03_RS21305 SH03_21315 glgC glgC 4289963 4291258 - glucose-1-phosphate adenylyltransferase catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate gene gene4251 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21305 SH03_RS21310 SH03_21320 SH03_RS21310 4291276 4293249 - glycogen debranching protein catalyzes the hydrolysis of the alpha-1%2C6-glucosidic linkages in partially depolymerized glycogen gene gene4252 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21310 SH03_RS21315 SH03_21325 SH03_RS21315 4293246 4295432 - 1%2C4-alpha-glucan-branching protein gene gene4253 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21315 SH03_RS21320 SH03_21330 SH03_RS21320 4295705 4296808 - aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene4254 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21320 SH03_RS21325 SH03_21335 SH03_RS21325 4297001 4297594 + membrane protein gene gene4255 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21325 SH03_RS21330 SH03_21340 SH03_RS21330 4297651 4298991 - low-affinity gluconate transporter gene gene4256 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21330 SH03_RS21335 SH03_21345 gntK gntK 4298995 4299522 - thermoresistant gluconokinase thermoresistant%3B catalyzes the formation of 6-phospho-D-gluconate from gluconate gene gene4257 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21335 SH03_RS21340 SH03_21350 SH03_RS21340 4299661 4300656 - GntR family transcriptional regulator gene gene4258 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21340 SH03_RS21345 SH03_21355 SH03_RS21345 4300880 4301575 - quercetin 2%2C3-dioxygenase gene gene4259 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21345 SH03_RS21350 SH03_21360 SH03_RS21350 4301698 4302735 - oxidoreductase gene gene4260 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21350 SH03_RS21355 SH03_21365 SH03_RS21355 4303068 4303556 + aminoacyl nucleotide detoxifying acetyltransferase YhhY%3B regulated by the fur regulator%3B unknown function gene gene4261 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21355 SH03_RS21360 SH03_21370 SH03_RS21360 4303793 4304971 + colicin gene gene4262 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21360 SH03_RS21365 SH03_21375 SH03_RS21365 4304968 4305384 + hypothetical protein gene gene4263 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21365 SH03_RS21370 SH03_21380 SH03_RS21370 4305607 4306110 + transposase gene gene4264 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21370 SH03_RS21375 SH03_21385 SH03_RS21375 4306689 4306973 + heat-shock protein gene gene4265 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21375 SH03_RS21380 SH03_21390 ggt ggt 4307011 4308753 - gamma-glutamyltranspeptidase periplasmic enzyme%3B post-translationally processed into two subunits which are required for wild-type enzyme activity%3B cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides gene gene4266 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21380 SH03_RS21385 SH03_21395 SH03_RS21385 4308873 4309313 + DUF2756 domain-containing protein gene gene4267 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21385 SH03_RS21390 SH03_21400 ugpQ ugpQ 4309300 4310043 - glycerophosphoryl diester phosphodiesterase hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol%3B induced when cells are starved for inorganic phosphate gene gene4268 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21390 SH03_RS21395 SH03_21405 ugpC ugpC 4310040 4311110 - sn-glycerol-3-phosphate import ATP-binding protein UgpC part of the UgpABCE glycerol-3-phosphate uptake system gene gene4269 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21395 SH03_RS21400 SH03_21410 SH03_RS21400 4311112 4311957 - sn-glycerol 3-phosphate ABC transporter permease with UgpABC is involved in uptake of glycerol-3-phosphate gene gene4270 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21400 SH03_RS21405 SH03_21415 SH03_RS21405 4311954 4312841 - sn-glycerol 3-phosphate ABC transporter permease with UgpEC is involved in the uptake of glycerol-3-phosphate gene gene4271 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21405 SH03_RS21410 SH03_21420 SH03_RS21410 4312939 4314255 - sn-glycerol-3-phosphate-binding periplasmic protein UgpB with UgpACE is involved in the uptake of glycerol-3-phosphate gene gene4272 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21410 SH03_RS21415 SH03_21425 SH03_RS21415 4314490 4314618 - hypothetical protein gene gene4273 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21415 SH03_RS21420 SH03_21430 livF livF 4314654 4315367 - branched-chain amino acid ABC transporter ATP-binding protein with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene4274 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21420 SH03_RS21425 SH03_21435 livG livG 4315369 4316136 - branched-chain amino acid ABC transporter ATP-binding protein Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene4275 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21425 SH03_RS21430 SH03_21440 livM livM 4316133 4317410 - branched-chain amino acid ABC transporter permease Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene4276 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21430 SH03_RS21435 SH03_21445 SH03_RS21435 4317407 4318333 - branched-chain amino acid ABC transporter permease LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter gene gene4277 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21435 SH03_RS21440 SH03_21450 SH03_RS21440 4318381 4319490 - leucine-specific-binding protein with LivFGHM is involved in the high affinity leucine transport gene gene4278 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21440 SH03_RS21445 SH03_21455 SH03_RS21445 4319914 4320297 + pantothenate synthesis PanD autocleavage accelerator gene gene4279 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21445 SH03_RS21450 SH03_21460 SH03_RS21450 4320307 4320429 + hypothetical protein gene gene4280 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21450 SH03_RS21455 SH03_21465 SH03_RS21455 4320485 4321603 - amino acid ABC transporter substrate-binding protein with LivFGHM is involved in the high affinity leucine transport gene gene4281 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21455 SH03_RS21460 SH03_21470 SH03_RS21460 4321859 4322713 - RNA polymerase sigma factor RpoH binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene4282 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21460 SH03_RS21465 SH03_21475 ftsX ftsX 4322958 4324016 - cell division protein FtsX ABC transporter%2C membrane protein gene gene4283 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21465 SH03_RS21470 SH03_21480 SH03_RS21470 4324009 4324677 - cell division ATP-binding protein FtsE ATP-binding protein of an ATP-binding cassette transporter%3B when bound to FtsX%2C FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions gene gene4284 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21470 SH03_RS21475 SH03_21485 SH03_RS21475 4324680 4326173 - signal recognition particle receptor FtsY cell division protein%3B signal recognition protein receptor%3B functions in the targeting and insertion of membrane proteins gene gene4285 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21475 SH03_RS21480 SH03_21490 rsmD rsmD 4326323 4326919 + ribosomal RNA small subunit methyltransferase D catalyzes the methylation of 16S rRNA at position G966 gene gene4286 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21480 SH03_RS21485 SH03_21495 SH03_RS21485 4326909 4327178 + DUF1145 domain-containing protein gene gene4287 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21485 SH03_RS21490 SH03_21500 SH03_RS21490 4327181 4327540 - DUF2500 domain-containing protein gene gene4288 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21490 SH03_RS21495 SH03_21505 SH03_RS21495 4327681 4328307 + membrane protein gene gene4289 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21495 SH03_RS21500 SH03_21510 zntA zntA 4328381 4330579 + cadmium-transporting ATPase P-type ATPase involved in the export of lead%2C cadmium%2C zinc and mercury gene gene4290 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21500 SH03_RS21505 SH03_21515 SH03_RS21505 4330681 4330926 - sulfurtransferase TusA TusA%3B transfers sulfur to TusBCD complex%3B involved in thiouridation of U34 position of some tRNAs gene gene4291 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21505 SH03_RS21510 SH03_21520 SH03_RS21510 4331147 4331812 + hypothetical protein gene gene4292 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21510 SH03_RS21515 SH03_21525 SH03_RS21515 4331885 4332442 + protein DcrB gene gene4293 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21515 SH03_RS21520 SH03_21530 SH03_RS21520 4332446 4333663 - arabinose efflux transporter gene gene4294 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21520 SH03_RS21525 SH03_21535 SH03_RS21525 4333795 4334844 + pheromone autoinducer 2 transporter gene gene4295 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21525 SH03_RS21530 SH03_21540 SH03_RS21530 4334899 4335486 + 4'-phosphopantetheinyl transferase gene gene4296 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21530 SH03_RS21535 SH03_21545 SH03_RS21535 4335597 4337171 + nickel-binding periplasmic protein gene gene4297 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21535 SH03_RS21540 SH03_21550 SH03_RS21540 4337171 4338115 + nickel ABC transporter permease with NikACDE is involved in nickel transport into the cell gene gene4298 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21540 SH03_RS21545 SH03_21555 nikC nikC 4338112 4338945 + nickel ABC transporter permease with NikABDE is involved in nickel transport into the cell gene gene4299 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21545 SH03_RS21550 SH03_21560 nikD nikD 4338945 4339709 + nickel ABC transporter ATP-binding protein with NikABCE is involved in nickel transport into the cell gene gene4300 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21550 SH03_RS21555 SH03_21565 nikE nikE 4339706 4340512 + nickel import ATP-binding protein NikE with NikABCD is involved with nickel transport into the cell gene gene4301 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21555 SH03_RS21560 SH03_21570 SH03_RS21560 4340518 4340919 + nickel-responsive regulator Inhibits transcription at high concentrations of nickel gene gene4302 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21560 SH03_RS21565 SH03_21575 SH03_RS21565 4341122 4345357 + RHS element protein gene gene4303 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21565 SH03_RS21570 SH03_21580 SH03_RS21570 4345329 4345712 + hypothetical protein gene gene4304 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21570 SH03_RS21575 SH03_RS21575 SH03_RS21575 4345817 4346167 + lyase gene gene4305 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21575 SH03_RS21580 SH03_21590 SH03_RS21580 4346308 4347444 + H repeat-associated protein YhhI gene gene4306 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21580 SH03_RS21585 SH03_21595 SH03_RS21585 4347609 4348733 - inner membrane transport permease YhhJ gene gene4307 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21585 SH03_RS21590 SH03_21600 SH03_RS21590 4348733 4351468 - ribosome-associated ATPase gene gene4308 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21590 SH03_RS21595 SH03_21605 SH03_RS21595 4351465 4352532 - membrane fusion protein (MFP) of efflux pump gene gene4309 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21595 SH03_RS21600 SH03_21610 SH03_RS21600 4352898 4354520 - hypothetical protein gene gene4310 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21600 SH03_RS21605 SH03_RS21605 SH03_RS21605 4354782 4356388 - hypothetical protein gene gene4311 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21605 SH03_RS21610 SH03_21620 SH03_RS21610 4356375 4356572 - hypothetical protein gene gene4312 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21610 SH03_RS21615 SH03_21625 SH03_RS21615 4356701 4356799 - hypothetical protein gene gene4313 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21615 SH03_RS21620 SH03_21630 SH03_RS21620 4356816 4357823 + membrane protein gene gene4314 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21620 SH03_RS21625 SH03_21635 SH03_RS21625 4358138 4359340 - oxidoreductase gene gene4315 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21625 SH03_RS21630 SH03_21640 SH03_RS21630 4359572 4361071 + Low-affinity inorganic phosphate transporter 1 involved in the transport of inorganic phosphate gene gene4316 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21630 SH03_RS21635 SH03_21645 SH03_RS21635 4361315 4361650 - universal stress protein B ppGpp-dependent%2C membrane associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene4317 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21635 SH03_RS21640 SH03_21650 SH03_RS21640 4362041 4362475 + universal stress protein A involved in resistance to DNA-damaging agents gene gene4318 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21640 SH03_RS21645 SH03_21655 tppB tppB 4362792 4364261 + dipeptide and tripeptide permease B mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium%3B member of proton-dependent oligopeptide transport (POT) system family%3B in Escherichia coli this gene is regulated by OmpR although not via osmoregulation gene gene4319 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21645 SH03_RS21650 SH03_21660 SH03_RS21650 4364310 4365062 - ribosomal RNA small subunit methyltransferase J predicted SAM-dependent methyltransferase gene gene4320 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21650 SH03_RS21655 SH03_21665 SH03_RS21655 4365070 4367112 - oligopeptidase A gene gene4321 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21655 SH03_RS21660 SH03_21670 SH03_RS21660 4367315 4368157 + ribosomal RNA large subunit methyltransferase J gene gene4322 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21660 SH03_RS21665 SH03_21675 SH03_RS21665 4368229 4369581 + glutathione reductase catalyzes the reduction of 2 glutathione to glutathione disulfide%3B maintains high levels of reduced glutathione in the cytosol%3B involved in redox regulation and oxidative defense gene gene4323 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21665 SH03_RS21670 SH03_21680 SH03_RS21670 4369635 4369751 - hypothetical protein gene gene4324 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21670 SH03_RS21675 SH03_21685 SH03_RS21675 4369746 4369919 + hypothetical protein gene gene4325 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21675 SH03_RS21680 SH03_21690 SH03_RS21680 4370458 4370811 + arsenical resistance operon repressor regulates the expression of of the arsRBC involved in resistance to arsenic gene gene4326 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21680 SH03_RS21685 SH03_21695 SH03_RS21685 4370865 4372154 + arsenical pump membrane protein gene gene4327 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21685 SH03_RS21690 SH03_21700 SH03_RS21690 4372167 4372592 + arsenate reductase gene gene4328 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21690 SH03_RS21695 SH03_21705 SH03_RS21695 4373221 4374003 + hypothetical protein gene gene4329 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21695 SH03_RS21700 SH03_21710 SH03_RS21700 4374112 4375092 - transposase gene gene4330 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21700 SH03_RS21705 SH03_RS21705 SH03_RS21705 4375158 4375643 + hypothetical protein gene gene4331 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21705 SH03_RS21710 SH03_21720 SH03_RS21710 4375891 4376457 + outer membrane protein slp gene gene4332 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21710 SH03_RS21715 SH03_21725 SH03_RS21715 4376613 4377143 + transcriptional regulator gene gene4333 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21715 SH03_RS21720 SH03_21730 SH03_RS21720 4377185 4377832 - magnesium transporter ATPase gene gene4334 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21720 SH03_RS21725 SH03_21735 hdeB hdeB 4377896 4378222 - acid stress chaperone HdeB gene gene4335 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21725 SH03_RS21730 SH03_21740 SH03_RS21730 4378338 4378670 - acid stress chaperone HdeA inactive form gene gene4336 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21730 SH03_RS21735 SH03_21745 SH03_RS21735 4378925 4379497 + protein HdeD gene gene4337 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21735 SH03_RS21740 SH03_21750 SH03_RS21740 4380296 4380823 + transcriptional regulator GadE gene gene4338 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21740 SH03_RS21745 SH03_21755 SH03_RS21745 4380824 4381102 - hypothetical protein gene gene4339 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21745 SH03_RS21750 SH03_21760 SH03_RS21750 4381162 4382319 + multidrug resistance protein MdtE gene gene4340 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21750 SH03_RS21755 SH03_21765 SH03_RS21755 4382344 4385457 + multidrug efflux RND transporter permease subunit gene gene4341 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21755 SH03_RS21760 SH03_21770 SH03_RS21760 4385820 4386548 - transcriptional regulator gene gene4342 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21760 SH03_RS21765 SH03_21775 SH03_RS21765 4386916 4387740 - transcriptional regulator regulates genes in response to acid and/or during stationary phase gene gene4343 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21765 SH03_RS21770 SH03_21780 SH03_RS21770 4388110 4389510 - glutamate decarboxylase alpha gene gene4344 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21770 SH03_RS21775 SH03_21785 SH03_RS21775 4389721 4391118 - cytochrome c peroxidase gene gene4345 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21775 SH03_RS21780 SH03_21790 treF treF 4391522 4393171 + trehalase cytoplasmic%3B catalyzes the hydrolysis of trehalose to glucose gene gene4346 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21780 SH03_RS21785 SH03_21795 SH03_RS21785 4393222 4393824 - LuxR family transcriptional regulator gene gene4347 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21785 SH03_RS21790 SH03_21800 SH03_RS21790 4394344 4395243 + LysR family transcriptional regulator gene gene4348 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21790 SH03_RS21795 SH03_21805 SH03_RS21795 4395292 4396305 + hypothetical protein gene gene4349 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21795 SH03_RS21800 SH03_21810 SH03_RS21800 4396716 4398038 + metabolite transporter gene gene4350 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21800 SH03_RS21805 SH03_21815 SH03_RS21805 4398220 4400280 - hypothetical protein gene gene4351 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21805 SH03_RS21810 SH03_21820 SH03_RS21810 4400350 4401117 - cyclic di-GMP phosphodiesterase YhjH in Escherichia coli this protein is involved in flagellar function gene gene4352 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21810 SH03_RS21815 SH03_21825 SH03_RS21815 4401071 4401265 + hypothetical protein gene gene4353 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21815 SH03_RS21820 SH03_21830 SH03_RS21820 4401349 4402278 + 2-dehydro-3-deoxygluconokinase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate gene gene4354 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21820 SH03_RS21825 SH03_21835 SH03_RS21825 4402374 4403870 - hypothetical protein gene gene4355 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21825 SH03_RS21830 SH03_21840 SH03_RS21830 4404091 4405377 - C4-dicarboxylate ABC transporter involved in the transport of C4-dicarboxylates across the membrane gene gene4356 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21830 SH03_RS21835 SH03_21845 SH03_RS21835 4405560 4407515 - biofilm formation regulator HmsP HmsP in Yersinia pestis plays a role in invasion of epithelial cells%3B the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation%3B inner membrane protein gene gene4357 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21835 SH03_RS21840 SH03_21850 SH03_RS21840 4407630 4411103 - cellulose synthase operon protein C cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium%3B the cellulose biosynthesis genes bcsA%2C bcsB%2C bcsZ and bcsC are constitutively transcribed%2C however%2C cellulose synthesis is dependent on the expression of adrA gene gene4358 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21840 SH03_RS21845 SH03_21855 SH03_RS21845 4411085 4412191 - endoglucanase catalyzes the hydrolysis of 1%2C4-beta-D-glucosidic linkages in cellulose%2C lichenin and cereal beta-D-glucans gene gene4359 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21845 SH03_RS21850 SH03_21860 SH03_RS21850 4412198 4414537 - cyclic di-GMP-binding protein binds the cellulose synthase activator%2C bis-(3'-5') cyclic diguanylic acid (c-di-GMP) gene gene4360 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21850 SH03_RS21855 SH03_21865 bcsA bcsA 4414548 4417166 - cellulose synthase catalytic subunit [UDP-forming] polymerizes uridine 5'-diphosphate glucose to cellulose%3B acts with BcsB%2C BcsZ and BcsC in cellulose biosynthesis gene gene4361 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21855 SH03_RS21860 SH03_21870 SH03_RS21860 4417163 4417834 - cell division protein gene gene4362 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21860 SH03_RS21865 SH03_21875 SH03_RS21865 4417927 4418115 - hypothetical protein gene gene4363 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21865 SH03_RS21870 SH03_21880 SH03_RS21870 4418506 4419486 - transposase gene gene4364 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21870 SH03_RS21875 SH03_21885 SH03_RS21875 4419599 4421158 + cellulose biosynthesis protein BcsE required for cellulose biosynthesis gene gene4365 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21875 SH03_RS21880 SH03_21890 SH03_RS21880 4421155 4421346 + protein BcsF gene gene4366 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21880 SH03_RS21885 SH03_21895 SH03_RS21885 4421343 4423022 + protein BcsG gene gene4367 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21885 SH03_RS21890 SH03_RS21890 SH03_RS21890 4423109 4423216 - small toxic polypeptide LdrD gene gene4368 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21890 SH03_RS21895 SH03_21905 SH03_RS21895 4423381 4423542 - hypothetical protein gene gene4369 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21895 SH03_RS21900 SH03_21910 SH03_RS21900 4423692 4424963 + transporter gene gene4370 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21900 SH03_RS21905 SH03_21915 dppF dppF 4424993 4425997 - dipeptide transport ATP-binding protein DppF Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides gene gene4371 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21905 SH03_RS21910 SH03_21920 dppD dppD 4425994 4426977 - dipeptide transport ATP-binding protein DppD DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF gene gene4372 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21910 SH03_RS21915 SH03_21925 SH03_RS21915 4426988 4427890 - peptide ABC transporter permease gene gene4373 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21915 SH03_RS21920 SH03_21930 SH03_RS21920 4427900 4428919 - peptide ABC transporter permease gene gene4374 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21920 SH03_RS21925 SH03_21935 SH03_RS21925 4428937 4429164 + hypothetical protein gene gene4375 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21925 SH03_RS21930 SH03_21940 SH03_RS21930 4429227 4430834 - periplasmic dipeptide transporter DppABCDF is involved in the transport of dipeptides%3B also binds heme and mediates chemotaxis to dipeptides gene gene4376 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21930 SH03_RS21935 SH03_21945 SH03_RS21935 4431186 4431446 - hypothetical protein gene gene4377 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21935 SH03_RS21940 SH03_21950 SH03_RS21940 4431745 4431821 - tRNA-Pro tRNA gene4378 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21940 SH03_RS21945 SH03_21955 SH03_RS21945 4431913 4433604 - phosphoethanolamine transferase EptB catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide gene gene4379 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21945 SH03_RS21950 SH03_21960 SH03_RS21950 4433928 4435136 - pyruvate-inducible inner membrane protein transporter gene gene4380 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21950 SH03_RS21955 SH03_21965 SH03_RS21955 4435365 4436063 - autotransporter beta-domain protein gene gene4381 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21955 SH03_RS21960 SH03_21970 SH03_RS21960 4436221 4436784 + DNA-3-methyladenine glycosylase 1 gene gene4382 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21960 SH03_RS21965 SH03_21975 SH03_RS21965 4436781 4437221 + GNAT family acetyltransferase gene gene4383 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21965 SH03_RS21970 SH03_21980 SH03_RS21970 4437190 4439469 - biotin sulfoxide reductase catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene4384 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21970 SH03_RS21975 SH03_21985 SH03_RS21975 4439676 4440335 + lipoprotein gene gene4385 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21975 SH03_RS21980 SH03_21990 SH03_RS21980 4440439 4441413 + glyoxylate/hydroxypyruvate reductase B catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate gene gene4386 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21980 SH03_RS21985 SH03_21995 SH03_RS21985 4441463 4442173 - DUF3053 domain-containing protein gene gene4387 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21985 SH03_RS21990 SH03_22000 SH03_RS21990 4442607 4442897 + transcriptional regulator gene gene4388 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21990 SH03_RS21995 SH03_22005 SH03_RS21995 4443178 4443390 + cold-shock protein gene gene4389 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS21995 SH03_RS22000 SH03_22010 SH03_RS22000 4443577 4443729 - protein HokA gene gene4390 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22000 SH03_RS22005 SH03_22015 SH03_RS22005 4443809 4444330 + transposase gene gene4391 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22005 SH03_RS22010 SH03_22020 SH03_RS22010 4444327 4445178 + transposase gene gene4392 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22010 SH03_RS22015 SH03_22025 glyS glyS 4445457 4447526 - glycine--tRNA ligase subunit beta glycine--tRNA ligase beta chain%3B glyS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene4393 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22015 SH03_RS22020 SH03_22030 SH03_RS22020 4447536 4448447 - glycine--tRNA ligase subunit alpha gene gene4394 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22020 SH03_RS22025 SH03_22035 SH03_RS22025 4448542 4448841 - hypothetical protein gene gene4395 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22025 SH03_RS22030 SH03_22040 SH03_RS22030 4449016 4450011 + hypothetical protein involved in enterobacterial common antigen biosynthesis%3B catalyzes the addition of O-acetyl groups to the N-acetyl-D-glucosamine residues of the trisaccharide repeat units of the enterobacterial common antigen gene gene4396 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22030 SH03_RS22035 SH03_22045 SH03_RS22035 4450053 4450490 - hypothetical protein gene gene4397 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22035 SH03_RS22040 SH03_22050 SH03_RS22040 4450536 4450877 - hypothetical protein gene gene4398 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22040 SH03_RS22045 SH03_22055 SH03_RS22045 4451046 4452500 - xylulose kinase catalyzes the formation of D-xylulose-5-phosphate fro D-xylulose gene gene4399 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22045 SH03_RS22050 SH03_22060 SH03_RS22050 4452572 4453894 - xylose isomerase catalyzes the interconversion of D-xylose to D-xylulose gene gene4400 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22050 SH03_RS22055 SH03_RS22055 xylF xylF 4454182 4454559 + D-xylose transporter subunit XylF periplasmic substrate-binding component of the ATP-dependent xylose transport system%3B high affinity gene gene4401 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22055 SH03_RS22060 SH03_22070 SH03_RS22060 4454573 4455076 - transposase gene gene4402 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22060 SH03_RS22065 SH03_RS22065 xylF xylF 4455325 4456029 + D-xylose transporter subunit XylF periplasmic substrate-binding component of the ATP-dependent xylose transport system%3B high affinity gene gene4403 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22065 SH03_RS22070 SH03_22080 SH03_RS22070 4456107 4457648 + xylose import ATP-binding protein XylG with XylFH is part of the high affinity xylose ABC transporter gene gene4404 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22070 SH03_RS22075 SH03_22085 SH03_RS22075 4457626 4458807 + xylose ABC transporter permease gene gene4405 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22075 SH03_RS22080 SH03_22090 SH03_RS22080 4458885 4460063 + xylose operon regulatory protein gene gene4406 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22080 SH03_RS22085 SH03_22095 SH03_RS22085 4460259 4461083 - protein bax gene gene4407 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22085 SH03_RS22090 SH03_22100 malS malS 4461403 4463433 + alpha-amylase periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB%3B hydrolyzes alpha-(1%2C4) glycosidic linkages%3B contains internal disulfide bonds gene gene4408 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22090 SH03_RS22095 SH03_22105 avtA avtA 4463611 4464864 + valine--pyruvate aminotransferase transaminase C%3B catalyzes transamination of alanine%2C valine%2C and 2-aminobutyrate with their respective 2-keto acids%3B also catalyzes terminal step in valine biosynthesis gene gene4409 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22095 SH03_RS22100 SH03_22110 SH03_RS22100 4464868 4464996 + hypothetical protein gene gene4410 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22100 SH03_RS22105 SH03_22115 SH03_RS22105 4465015 4465488 - hydrogenase 4Fe-4S ferredoxin-type component gene gene4411 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22105 SH03_RS22110 SH03_22120 SH03_RS22110 4465590 4466438 - transcriptional regulator gene gene4412 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22110 SH03_RS22115 SH03_22125 SH03_RS22115 4466639 4467637 + 2%2C3-diketo-L-gulonate reductase NAD(P)H-dependent%3B catalyzes the reduction of 2%2C3-diketo-L-gulonate to 3-keto-L-gulonate gene gene4413 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22115 SH03_RS22120 SH03_22130 SH03_RS22120 4467649 4468116 + hypothetical protein gene gene4414 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22120 SH03_RS22125 SH03_22135 SH03_RS22125 4468234 4468707 + 2%2C3-diketo-L-gulonate TRAP transporter permease membrane-spanning protein involved in uptake of 2%2C3-diketo-L-gulonate%3B part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO gene gene4415 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22125 SH03_RS22130 SH03_22140 SH03_RS22130 4468710 4469987 + 2%2C3-diketo-L-gulonate TRAP transporter permease TRAP family transporter%3B with YiaMO is involved in the uptake of L-dehydroascorbate gene gene4416 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22130 SH03_RS22135 SH03_22145 SH03_RS22135 4470000 4470986 + 2%2C3-diketo-L-gulonate ABC transporter substrate-binding protein involved in the transport of 2%2C3-diketo-L-gulonate gene gene4417 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22135 SH03_RS22140 SH03_22150 SH03_RS22140 4470990 4472486 + L-xylulose/3-keto-L-gulonate kinase catalyzes the formation of L-xylulose 5-phosphate and 3-dehydro-L-gulonate 6-phosphate from L-xylulose or 3-dehydro-L-gulonate%2C respectively gene gene4418 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22140 SH03_RS22145 SH03_22155 sgbH sgbH 4472483 4473145 + 3-keto-L-gulonate-6-phosphate decarboxylase sgbH catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate gene gene4419 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22145 SH03_RS22150 SH03_22160 SH03_RS22150 4473138 4473998 + L-xylulose 5-phosphate 3-epimerase L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated%3B may be involved in the utilization of 2%2C3-diketo-L-gulonate gene gene4420 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22150 SH03_RS22155 SH03_22165 araD araD 4473992 4474687 + L-ribulose-5-phosphate 4-epimerase SgbE catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene4421 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22155 SH03_RS22160 SH03_22170 SH03_RS22160 4475034 4475774 - outer membrane protein gene gene4422 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22160 SH03_RS22165 SH03_22175 SH03_RS22165 4475898 4476872 + transcriptional regulator gene gene4423 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22165 SH03_RS22170 SH03_22180 SH03_RS22170 4476869 4478005 - hypothetical protein gene gene4424 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22170 SH03_RS22175 SH03_22185 SH03_RS22175 4478011 4478334 - hypothetical protein gene gene4425 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22175 SH03_RS22180 SH03_RS22180 SH03_RS22180 4478448 4478660 + membrane protein gene gene4426 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22180 SH03_RS22185 SH03_22195 SH03_RS22185 4478879 4480417 - aldehyde dehydrogenase B catalyzes the oxidation of acetaldehyde%2C benzaldehyde%2C propionaldehyde and other aldehydes gene gene4427 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22185 SH03_RS22190 SH03_22200 SH03_RS22190 4480582 4481733 - alcohol dehydrogenase gene gene4428 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22190 SH03_RS22195 SH03_22205 SH03_RS22195 4481923 4483767 - selenocysteine-specific translation elongation factor gene gene4429 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22195 SH03_RS22200 SH03_22210 SH03_RS22200 4483764 4485155 - L-seryl-tRNA(Sec) selenium transferase catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis gene gene4430 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22200 SH03_RS22205 SH03_22215 SH03_RS22205 4485253 4485861 - glutathione S-transferase gene gene4431 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22205 SH03_RS22210 SH03_22220 SH03_RS22210 4486089 4490222 + RHS element protein RhsA gene gene4432 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22210 SH03_RS22215 SH03_22225 SH03_RS22215 4490243 4491085 + hypothetical protein gene gene4433 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22215 SH03_RS22220 SH03_22230 SH03_RS22220 4491133 4491828 + hypothetical protein gene gene4434 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22220 SH03_RS22225 SH03_22235 SH03_RS22225 4492083 4492544 + hypothetical protein gene gene4435 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22225 SH03_RS22230 SH03_RS22230 SH03_RS22230 4493251 4493689 + hypothetical protein gene gene4436 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22230 SH03_RS22235 SH03_22245 SH03_RS22235 4494149 4495285 - hypothetical protein gene gene4437 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22235 SH03_RS22240 SH03_22250 SH03_RS22240 4495288 4495650 - DUF3302 domain-containing protein gene gene4438 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22240 SH03_RS22245 SH03_RS22245 SH03_RS22245 4496187 4498098 + PTS mannitol transporter subunit IICBA catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIC forms the translocation channel and contains the specific substrate-binding site%3B subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit%3B subunit IIB transfers the phosphoryl group to the substrate gene gene4439 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22245 SH03_RS22250 SH03_22260 SH03_RS22250 4498328 4499476 + mannitol-1-phosphate 5-dehydrogenase gene gene4440 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22250 SH03_RS22255 SH03_22265 SH03_RS22255 4499473 4500063 + hypothetical protein gene gene4441 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22255 SH03_RS22260 SH03_22270 SH03_RS22260 4500075 4500284 - hypothetical protein gene gene4442 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22260 SH03_RS22265 SH03_22275 SH03_RS22265 4500569 4500931 + DUF2810 domain-containing protein gene gene4443 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22265 SH03_RS22270 SH03_22280 SH03_RS22270 4501303 4502958 + L-lactate permease gene gene4444 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22270 SH03_RS22275 SH03_22285 SH03_RS22275 4502958 4503734 + dual role activator/repressor for lldPRD operon represses the lctPRD operon gene gene4445 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22275 SH03_RS22280 SH03_22290 lldD lldD 4503731 4504921 + lactate dehydrogenase flavin mononucleotide-dependent dehydrogenase%3B functions in aerobic respiration and also has a role in anaerobic nitrate respiration gene gene4446 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22280 SH03_RS22285 SH03_22295 SH03_RS22285 4505119 4505592 + tRNA (cytidine(34)-2'-O)-methyltransferase member of the SPOUT superfamily of RNA methyltransferases gene gene4447 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22285 SH03_RS22290 SH03_22300 cysE cysE 4505645 4506466 - serine acetyltransferase catalyzes the O-acetylation of serine gene gene4448 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22290 SH03_RS22295 SH03_22305 SH03_RS22295 4506546 4507565 - glycerol-3-phosphate dehydrogenase [NAD(P)+] gene gene4449 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22295 SH03_RS22300 SH03_22310 SH03_RS22300 4507565 4508032 - preprotein translocase subunit SecB molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm%3B in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA gene gene4450 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22300 SH03_RS22305 SH03_22315 SH03_RS22305 4508095 4508346 - glutaredoxin gene gene4451 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22305 SH03_RS22310 SH03_22320 SH03_RS22310 4508488 4508919 - hypothetical protein gene gene4452 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22310 SH03_RS22315 SH03_22325 SH03_RS22315 4508947 4509057 - hypothetical protein gene gene4453 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22315 SH03_RS22320 SH03_22330 SH03_RS22320 4509164 4510708 + 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gene gene4454 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22320 SH03_RS22325 SH03_22335 SH03_RS22325 4510718 4512001 + peptidase M37 gene gene4455 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22325 SH03_RS22330 SH03_22340 SH03_RS22330 4512005 4512964 + polysaccharide deacetylase gene gene4456 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22330 SH03_RS22335 SH03_22345 SH03_RS22335 4512951 4513985 - LPS(HepIII)-glucuronic acid glycosyltransferase gene gene4457 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22335 SH03_RS22340 SH03_22350 tdh tdh 4514224 4515249 - l-threonine 3-dehydrogenase converts threonine and NAD to 1%2C2-amino-3-oxobutanoate and NADH%3B functions in threonine catabolism gene gene4458 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22340 SH03_RS22345 SH03_22355 SH03_RS22345 4515259 4516455 - 2-amino-3-ketobutyrate CoA ligase catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine gene gene4459 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22345 SH03_RS22350 SH03_22360 SH03_RS22350 4516730 4517587 - protein HtrL gene gene4460 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22350 SH03_RS22355 SH03_22365 rfaD rfaD 4517891 4518823 + ADP-L-glycero-D-manno-heptose-6-epimerase catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose gene gene4461 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22355 SH03_RS22360 SH03_22370 SH03_RS22360 4518833 4519879 + ADP-heptose--LPS heptosyltransferase 2 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core gene gene4462 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22360 SH03_RS22365 SH03_22375 SH03_RS22365 4519883 4520842 + LPS heptosyltransferase 1 gene gene4463 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22365 SH03_RS22370 SH03_22380 SH03_RS22370 4520852 4522111 + O-antigen ligase gene gene4464 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22370 SH03_RS22375 SH03_22385 SH03_RS22375 4522143 4523216 - LPS 1%2C2-N-acetylglucosaminetransferase gene gene4465 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22375 SH03_RS22380 SH03_22390 SH03_RS22380 4523249 4524100 - 3-deoxy-D-manno-oct-2-ulosonate III transferase WaaZ gene gene4466 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22380 SH03_RS22385 SH03_22395 SH03_RS22385 4524171 4524869 - LPS core heptose(II) kinase RfaY catalyzes the phosphorylation of heptose(II) of the outer membrane lipopolysaccharide core gene gene4467 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22385 SH03_RS22390 SH03_22400 SH03_RS22390 4524887 4525903 - LPS 1%2C2-glucosyltransferase gene gene4468 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22390 SH03_RS22395 SH03_22405 SH03_RS22395 4525943 4526962 - LPS 1%2C3-galactosyltransferase gene gene4469 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22395 SH03_RS22400 SH03_22410 SH03_RS22400 4526962 4528041 - LPS 1%2C6-galactosyltransferase gene gene4470 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22400 SH03_RS22405 SH03_22415 SH03_RS22405 4528085 4529020 - LPS biosynthesis protein gene gene4471 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22405 SH03_RS22410 SH03_22420 SH03_RS22410 4529057 4529854 - LPS core heptose(I) kinase RfaP catalyzes the phosphorylation of heptose I in the lipopolysaccharide core gene gene4472 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22410 SH03_RS22415 SH03_22425 SH03_RS22415 4529847 4530971 - LPS biosynthesis protein catalyzes the addition of the first glucose residue to the LPS core gene gene4473 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22415 SH03_RS22420 SH03_22430 SH03_RS22420 4530968 4532002 - LPS core heptosyltransferase RfaQ catalyzes the transfer of heptose(III) to heptose(II) in the lipopolysaccharide inner core gene gene4474 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22420 SH03_RS22425 SH03_22435 SH03_RS22425 4532444 4533721 + 3-deoxy-D-manno-octulosonic acid transferase catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A gene gene4475 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22425 SH03_RS22430 SH03_22440 coaD coaD 4533729 4534208 + phosphopantetheine adenylyltransferase Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA gene gene4476 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22430 SH03_RS22435 SH03_22445 SH03_RS22435 4534247 4535056 - formamidopyrimidine-DNA glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases gene gene4477 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22435 SH03_RS22440 SH03_22450 rpmG rpmG 4535154 4535321 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene4478 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22440 SH03_RS22445 SH03_22455 rpmB rpmB 4535342 4535578 - 50S ribosomal protein L28 required for 70S ribosome assembly gene gene4479 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22445 SH03_RS22450 SH03_22460 SH03_RS22450 4535795 4536463 - hypothetical protein gene gene4480 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22450 SH03_RS22455 SH03_22465 SH03_RS22455 4536635 4537855 + CoA biosynthesis bifunctional protein CoaBC catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C which is then decarboxylated to form 4'-phosphopantotheine gene gene4481 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22455 SH03_RS22460 SH03_22470 SH03_RS22460 4537833 4538291 + deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene4482 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22460 SH03_RS22465 SH03_22475 slmA slmA 4538398 4538994 + nucleoid occlusion factor SlmA FtsZ binding protein%3B synthetically lethal with a defect in the Min system%3B this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly gene gene4483 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22465 SH03_RS22470 SH03_22480 pyrE pyrE 4539031 4539672 - orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene4484 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22470 SH03_RS22475 SH03_22485 rph rph 4539738 4540454 - ribonuclease PH RNase PH%3B tRNA nucleotidyltransferase%3B forms hexamers in Bacillus subtilis%3B phosphoroltic 3'-5' exoribonuclease%3B involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs gene gene4485 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22475 SH03_RS22480 SH03_22490 SH03_RS22480 4540581 4541444 + hypothetical protein gene gene4486 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22480 SH03_RS22485 SH03_22495 dinD dinD 4541665 4542489 + DNA-damage-inducible protein D gene gene4487 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22485 SH03_RS22490 SH03_22500 SH03_RS22490 4542779 4543396 + hypothetical protein gene gene4488 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22490 SH03_RS22495 SH03_22505 ligB ligB 4543393 4545075 - DNA ligase B this ligase is similar to LigA but it lacks the C-terminal BRCT domain%3B catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ gene gene4489 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22495 SH03_RS22500 SH03_22510 gmk gmk 4545333 4545956 + guanylate kinase Essential for recycling GMP and indirectly%2C cGMP gene gene4490 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22500 SH03_RS22505 SH03_22515 rpoZ rpoZ 4546011 4546286 + DNA-directed RNA polymerase subunit omega Promotes RNA polymerase assembly%3B latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gene gene4491 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22505 SH03_RS22510 SH03_22520 SH03_RS22510 4546305 4548413 + bifunctional (p)ppGpp synthetase II/ guanosine-3'%2C5'-bis pyrophosphate 3'-pyrophosphohydrolase gene gene4492 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22510 SH03_RS22515 SH03_22525 SH03_RS22515 4548420 4549109 + tRNA (guanosine(18)-2'-O)-methyltransferase specifically modifies tRNA at position G18 gene gene4493 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22515 SH03_RS22520 SH03_22530 SH03_RS22520 4549115 4551196 + ATP-dependent DNA helicase RecG catalyzes branch migration in Holliday junction intermediates gene gene4494 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22520 SH03_RS22525 SH03_22535 SH03_RS22525 4551365 4552570 - sodium/glutamate symport carrier protein is involved with the sodium-dependent uptake of glutamate gene gene4495 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22525 SH03_RS22530 SH03_22540 SH03_RS22530 4552850 4554241 + xanthine permease XanP high-affinity transporter for xanthine gene gene4496 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22530 SH03_RS22535 SH03_22545 SH03_RS22535 4554362 4556071 + AsmA family protein gene gene4497 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22535 SH03_RS22540 SH03_22550 SH03_RS22540 4556124 4558442 - alpha-xylosidase catalyzes the transfer of alpha-xylosyl residue gene gene4498 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22540 SH03_RS22545 SH03_22555 SH03_RS22545 4558452 4559834 - inner membrane symporter YicJ may be involved in the transport of galactosides-pentoses-hexuronides gene gene4499 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22545 SH03_RS22550 SH03_22560 SH03_RS22550 4560127 4560221 + tRNA-Sec tRNA gene4500 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22550 SH03_RS22555 SH03_22565 SH03_RS22555 4560330 4560476 + hypothetical protein gene gene4501 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22555 SH03_RS22560 SH03_22570 SH03_RS22560 4560858 4562042 + sugar efflux transporter C gene gene4502 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22560 SH03_RS22565 SH03_22575 SH03_RS22565 4562153 4563076 + transporter gene gene4503 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22565 SH03_RS22570 SH03_22580 SH03_RS22570 4563080 4563898 - lipoprotein 28 gene gene4504 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22570 SH03_RS22575 SH03_22585 SH03_RS22575 4563996 4564115 + hypothetical protein gene gene4505 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22575 SH03_RS22580 SH03_22590 SH03_RS22580 4564120 4564413 + hypothetical protein gene gene4506 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22580 SH03_RS22585 SH03_22595 nepI nepI 4564454 4565644 - purine ribonucleoside efflux pump NepI experimental results in Escherichia coli suggest that this gene encodes an inosine export protein%3B member of major facilitator superfamily%3B MFS gene gene4507 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22585 SH03_RS22590 SH03_22600 SH03_RS22590 4565855 4566307 - DUF1198 domain-containing protein gene gene4508 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22590 SH03_RS22595 SH03_22605 SH03_RS22595 4566360 4567772 - adenine permease involved in the transport or adenine gene gene4509 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22595 SH03_RS22600 SH03_22610 SH03_RS22600 4567869 4569635 + adenine deaminase catalyzes the formation of hypoxanthine from adenine%3B in E. coli this activity has been detected in mutant strains but not in wild type gene gene4510 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22600 SH03_RS22605 SH03_22615 uhpT uhpT 4569681 4571072 - hexose phosphate transporter cytoplasmic membrane protein that functions as a monomer%3B catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate gene gene4511 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22605 SH03_RS22610 SH03_22620 SH03_RS22610 4571210 4572529 - regulatory protein UhpC membrane protein regulates uhpT expression gene gene4512 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22610 SH03_RS22615 SH03_22625 SH03_RS22615 4572539 4574041 - sensor protein UhpB Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph gene gene4513 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22615 SH03_RS22620 SH03_22630 SH03_RS22620 4574041 4574631 - transcriptional regulator response regulator in two-component regulatory system wtih UhpB%3B phosphorylated UhpA is a positive activator uhpT%2C a hexose phosphates transporter gene gene4514 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22620 SH03_RS22625 SH03_22635 SH03_RS22625 4574707 4574997 - acetolactate synthase isozyme 1 small subunit with IlvB catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase small subunit gene gene4515 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22625 SH03_RS22630 SH03_22640 SH03_RS22630 4575001 4576689 - acetolactate synthase isozyme 1 large subunit gene gene4516 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22630 SH03_RS22635 SH03_22645 SH03_RS22635 4576795 4576893 - IlvBN operon leader peptide gene gene4517 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22635 SH03_RS22640 SH03_22650 SH03_RS22640 4576880 4577170 + hypothetical protein gene gene4518 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22640 SH03_RS22645 SH03_22655 SH03_RS22645 4577167 4577325 + hypothetical protein gene gene4519 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22645 SH03_RS22650 SH03_22660 SH03_RS22650 4577458 4577547 + small toxic protein TisB gene gene4520 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22650 SH03_RS22655 SH03_22665 emrD emrD 4577827 4579011 + multidrug resistance protein D multidrug efflux protein involved in adaptation to low energy shock gene gene4521 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22655 SH03_RS22660 SH03_22670 SH03_RS22660 4579019 4579516 - hypothetical protein gene gene4522 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22660 SH03_RS22665 SH03_22675 SH03_RS22665 4579513 4579875 - hypothetical protein gene gene4523 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22665 SH03_RS22670 SH03_22680 SH03_RS22670 4579865 4580212 - hypothetical protein gene gene4524 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22670 SH03_RS22675 SH03_22685 SH03_RS22675 4580320 4580769 + hypothetical protein gene gene4525 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22675 SH03_RS22680 SH03_22690 SH03_RS22680 4580816 4582309 - sulfatase/phosphatase superfamily protein gene gene4526 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22680 SH03_RS22685 SH03_22695 SH03_RS22685 4582306 4584021 - transporter uncharacterized member of the SSS superfamily of sodium-dependent solute transporters%3B unknown function gene gene4527 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22685 SH03_RS22690 SH03_22700 SH03_RS22690 4584188 4585081 + AraC family transcriptional regulator gene gene4528 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22690 SH03_RS22695 SH03_22705 SH03_RS22695 4585254 4585892 - inactive 6-phospho-alpha-glucosidase gene gene4529 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22695 SH03_RS22700 SH03_22710 SH03_RS22700 4585892 4586377 - phosphotransferase enzyme IIB component GlvB gene gene4530 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22700 SH03_RS22705 SH03_22715 SH03_RS22705 4586402 4587508 - permease gene gene4531 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22705 SH03_RS22710 SH03_22720 SH03_RS22710 4587804 4588520 + transcriptional regulator gene gene4532 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22710 SH03_RS22715 SH03_22725 SH03_RS22715 4588517 4590178 - transporter gene gene4533 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22715 SH03_RS22720 SH03_22730 SH03_RS22720 4590374 4590802 - heat-shock protein IbpB 16 kDa heat shock protein B%3B associates with aggregated proteins%2C together with ibpA%2C to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress%3B ATP-independent gene gene4534 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22720 SH03_RS22725 SH03_22735 SH03_RS22725 4590914 4591327 - heat-shock protein IbpA with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress gene gene4535 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22725 SH03_RS22730 SH03_22740 SH03_RS22730 4591705 4591965 + hypothetical protein gene gene4536 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22730 SH03_RS22735 SH03_22745 SH03_RS22735 4591967 4593181 - hypothetical protein gene gene4537 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22735 SH03_RS22740 SH03_22750 SH03_RS22740 4593282 4594346 + protein CbrA FAD/NAD(P)-binding domain gene gene4538 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22740 SH03_RS22745 SH03_22755 SH03_RS22745 4594343 4595635 - D-galactonate transporter gene gene4539 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22745 SH03_RS22750 SH03_22760 SH03_RS22750 4595755 4596903 - D-galactonate dehydratase 2 gene gene4540 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22750 SH03_RS22755 SH03_22765 SH03_RS22755 4596900 4597517 - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate%3B functions in galactonate metabolism gene gene4541 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22755 SH03_RS22760 SH03_22770 SH03_RS22760 4597501 4598379 - 2-dehydro-3-deoxygalactonokinase catalyzes the formation of 2-dehydro-3-deoxy-D-galactonate 6-phosphate from 2-dehydro-3-deoxy-D-galactonate gene gene4542 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22760 SH03_RS22765 SH03_22775 SH03_RS22765 4598376 4599065 - transcriptional regulator gene gene4543 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22765 SH03_RS22770 SH03_22780 SH03_RS22770 4599343 4599999 + hypothetical protein gene gene4544 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22770 SH03_RS22775 SH03_22785 SH03_RS22775 4600045 4600857 - sugar phosphatase YidA YidA%3B catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate)%2C mannose 1-phosphate and p-nitrophenyl phosphate%3B hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form%3B member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins gene gene4545 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22775 SH03_RS22780 SH03_22790 SH03_RS22780 4600972 4601370 - DUF937 domain-containing protein gene gene4546 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22780 SH03_RS22785 SH03_22795 SH03_RS22785 4601390 4601590 - hypothetical protein gene gene4547 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22785 SH03_RS22790 SH03_22800 gyrB gyrB 4601610 4604024 - DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene4548 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22790 SH03_RS22795 SH03_22805 recF recF 4604053 4605126 - DNA recombination protein RecF Required for DNA replication%3B binds preferentially to single-stranded%2C linear DNA gene gene4549 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22795 SH03_RS22800 SH03_22810 SH03_RS22800 4605126 4606226 - DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene4550 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22800 SH03_RS22805 SH03_22815 dnaA dnaA 4606231 4607634 - chromosomal replication initiator protein DnaA binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication%3B can also affect transcription of multiple genes including itself. gene gene4551 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22805 SH03_RS22860 SH03_RS22860 SH03_RS22860 616524 617638 - phosphoethanolamine transferase YjgX gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22860 SH03_RS22865 SH03_RS22865 SH03_RS22865 635568 635861 + transposase gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22865 SH03_RS22870 SH03_RS22870 SH03_RS22870 1964908 1967555 + autotransporter gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22870 SH03_RS22875 SH03_RS22875 SH03_RS22875 2162729 2162884 - hypothetical protein gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22875 SH03_RS22880 SH03_RS22880 SH03_RS22880 3216409 3217165 - replication protein gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22880 SH03_RS22885 SH03_19760 SH03_RS22885 3999532 3999726 - propionate kinase gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=SH03_RS22885