locus-tag	class	description
SH06_RS00040	COG0814	amino acid
SH06_RS00055	COG2091	lysine biosynthetic process via aminoadipic acid
SH06_RS00060	COG0431	NADPH-dependent FMN reductase
SH06_RS00065	COG2252	PERMEase
SH06_RS00070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SH06_RS00080	COG3196	Protein conserved in bacteria
SH06_RS00085	COG0363	glucosamine-6-phosphate deaminase activity
SH06_RS00090	COG2382	esterase
SH06_RS00100	COG2723	6-phospho-beta-galactosidase activity
SH06_RS00105	COG2190	(PTS) system
SH06_RS00105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS00105	COG1263	PTS System
SH06_RS00110	COG3711	transcriptional antiterminator
SH06_RS00115	COG0704	Plays a role in the regulation of phosphate uptake
SH06_RS00120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SH06_RS00125	COG0581	inorganic phosphate transmembrane transporter activity
SH06_RS00130	COG0573	inorganic phosphate transmembrane transporter activity
SH06_RS00135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SH06_RS00140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SH06_RS00190	COG3312	ion transport
SH06_RS00205	COG0716	FMN binding
SH06_RS00210	COG1522	sequence-specific DNA binding
SH06_RS00240	COG1129	ABC transporter
SH06_RS00245	COG1172	Belongs to the binding-protein-dependent transport system permease family
SH06_RS00250	COG1879	ABC-type sugar transport system periplasmic component
SH06_RS00255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SH06_RS00260	COG1609	Transcriptional regulator
SH06_RS00265	COG0477	Major facilitator Superfamily
SH06_RS00270	COG2186	Transcriptional regulator
SH06_RS00310	COG3085	chromosome segregation
SH06_RS00315	COG0606	chelatase, subunit chli
SH06_RS00330	COG3978	acetolactate synthase activity
SH06_RS00335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SH06_RS00345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SH06_RS00350	COG0583	DNA-binding transcription factor activity
SH06_RS00360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SH06_RS00370	COG0210	DNA helicase
SH06_RS00385	COG3118	belongs to the thioredoxin family
SH06_RS00395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SH06_RS00405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SH06_RS00410	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
SH06_RS00415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SH06_RS00420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SH06_RS00425	COG1088	dTDP-glucose 4,6-dehydratase activity
SH06_RS00430	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SH06_RS00435	COG0456	acetyltransferase
SH06_RS00440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SH06_RS00445	COG2244	polysaccharide biosynthetic process
SH06_RS00465	COG1113	amino acid transport
SH06_RS00490	COG0641	radical SAM
SH06_RS00495	COG3119	arylsulfatase activity
SH06_RS00500	COG3071	HemY protein
SH06_RS00505	COG2959	enzyme of heme biosynthesis
SH06_RS00510	COG1587	Uroporphyrinogen-III synthase
SH06_RS00520	COG3072	Adenylate cyclase
SH06_RS00530	COG5567	small periplasmic lipoprotein
SH06_RS00550	COG1011	Hydrolase
SH06_RS00555	COG0210	DNA helicase
SH06_RS00560	COG3698	Phosphodiester glycosidase
SH06_RS00570	COG0598	Magnesium transport protein CorA
SH06_RS00585	COG2962	Rard protein
SH06_RS00590	COG2050	protein possibly involved in aromatic compounds catabolism
SH06_RS00595	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
SH06_RS00600	COG0514	ATP-dependent DNA helicase (RecQ)
SH06_RS00605	COG1280	lysine exporter protein (LysE YggA)
SH06_RS00610	COG1280	lysine exporter protein (LysE YggA)
SH06_RS00615	COG2267	carboxylic ester hydrolase activity
SH06_RS00620	COG0561	phosphatase activity
SH06_RS00625	COG0697	spore germination
SH06_RS00630	COG0583	DNA-binding transcription factor activity
SH06_RS00640	COG0412	Dienelactone hydrolase
SH06_RS00645	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SH06_RS00650	COG1322	Protein conserved in bacteria
SH06_RS00660	COG3165	ubiquinone biosynthetic process from chorismate
SH06_RS00670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SH06_RS00675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SH06_RS00680	COG0805	protein transport
SH06_RS00685	COG0084	hydrolase, TatD family'
SH06_RS00690	COG0250	Participates in transcription elongation, termination and antitermination
SH06_RS00695	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SH06_RS00700	COG0543	2 iron, 2 sulfur cluster binding
SH06_RS00705	COG0183	Belongs to the thiolase family
SH06_RS00720	COG1739	Uncharacterized protein family UPF0029
SH06_RS00725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SH06_RS00730	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
SH06_RS00760	COG1763	Mo-molybdopterin cofactor biosynthetic process
SH06_RS00765	COG0746	molybdenum cofactor guanylyltransferase activity
SH06_RS00770	COG3084	Protein conserved in bacteria
SH06_RS00775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SH06_RS00780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SH06_RS00785	COG5339	Protein conserved in bacteria
SH06_RS00790	COG0204	Acyl-transferase
SH06_RS00800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SH06_RS00800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SH06_RS00815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SH06_RS00825	COG2204	response regulator
SH06_RS00830	COG3852	Histidine kinase
SH06_RS00835	COG0174	glutamine synthetase
SH06_RS00845	COG1217	gtp-binding protein TYPA
SH06_RS00850	COG2188	Transcriptional regulator
SH06_RS00855	COG1082	Xylose isomerase domain protein TIM barrel
SH06_RS00860	COG2271	Major facilitator Superfamily
SH06_RS00865	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SH06_RS00870	COG2211	Major facilitator Superfamily
SH06_RS00875	COG2211	Major facilitator Superfamily
SH06_RS00880	COG1501	Belongs to the glycosyl hydrolase 31 family
SH06_RS00885	COG2017	converts alpha-aldose to the beta-anomer
SH06_RS00890	COG2942	2-epimerase
SH06_RS00895	COG3684	Belongs to the aldolase LacD family
SH06_RS00900	COG2084	Dehydrogenase
SH06_RS00905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SH06_RS00910	COG1349	DNA-binding transcription factor activity
SH06_RS00915	COG1011	Hydrolase
SH06_RS00930	COG0456	acetyltransferase
SH06_RS00935	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SH06_RS00940	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SH06_RS00955	COG2864	formate dehydrogenase
SH06_RS00960	COG0437	4 iron, 4 sulfur cluster binding
SH06_RS00965	COG3383	formate dehydrogenase (NAD+) activity
SH06_RS00965	COG0243	molybdopterin cofactor binding
SH06_RS00970	COG0243	molybdopterin cofactor binding
SH06_RS00970	COG3383	formate dehydrogenase (NAD+) activity
SH06_RS00985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS00985	COG3711	transcriptional antiterminator
SH06_RS00990	COG1363	Peptidase, m42
SH06_RS00995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS00995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS01000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS01045	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SH06_RS01060	COG2258	MOSC domain
SH06_RS01065	COG2205	protein histidine kinase activity
SH06_RS01070	COG0745	RESPONSE REGULATOR receiver
SH06_RS01075	COG3678	ATP-independent chaperone mediated protein folding
SH06_RS01090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
SH06_RS01110	COG3152	Membrane
SH06_RS01115	COG3691	Protein conserved in bacteria
SH06_RS01120	COG0589	response to stress
SH06_RS01125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SH06_RS01130	COG1494	fructose-1,6-bisphosphatase
SH06_RS01140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SH06_RS01155	COG1575	Belongs to the MenA family. Type 1 subfamily
SH06_RS01170	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SH06_RS01175	COG1609	Transcriptional regulator
SH06_RS01180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SH06_RS01190	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
SH06_RS01200	COG0626	cystathionine gamma-synthase activity
SH06_RS01205	COG0527	aspartate kinase activity
SH06_RS01205	COG0460	homoserine dehydrogenase
SH06_RS01215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SH06_RS01225	COG0697	spore germination
SH06_RS01230	COG3738	Protein conserved in bacteria
SH06_RS01240	COG0371	Dehydrogenase
SH06_RS01245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SH06_RS01250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SH06_RS01250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS01250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS01255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS01260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS01265	COG1882	Formate acetyltransferase
SH06_RS01270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SH06_RS01275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS01280	COG2207	Transcriptional regulator
SH06_RS01285	COG2194	sulfuric ester hydrolase activity
SH06_RS01305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SH06_RS01320	COG0583	DNA-binding transcription factor activity
SH06_RS01345	COG4206	TonB-dependent receptor
SH06_RS01375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SH06_RS01380	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SH06_RS01380	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SH06_RS01420	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SH06_RS01425	COG0250	Participates in transcription elongation, termination and antitermination
SH06_RS01465	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SH06_RS01475	COG2104	thiamine diphosphate biosynthetic process
SH06_RS01480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SH06_RS01515	COG3068	Protein conserved in bacteria
SH06_RS01530	COG3678	ATP-independent chaperone mediated protein folding
SH06_RS01535	COG4191	Histidine kinase
SH06_RS01540	COG2204	response regulator
SH06_RS01545	COG0151	Belongs to the GarS family
SH06_RS01590	COG0456	acetyltransferase
SH06_RS01600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SH06_RS01605	COG2224	Isocitrate lyase
SH06_RS01620	COG1414	Transcriptional regulator
SH06_RS01625	COG0646	methionine synthase
SH06_RS01625	COG1410	methionine synthase
SH06_RS01630	COG1283	sodium-dependent phosphate transmembrane transporter activity
SH06_RS01640	COG1187	pseudouridine synthase activity
SH06_RS01650	COG0527	aspartate kinase activity
SH06_RS01675	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SH06_RS01695	COG2814	Major facilitator Superfamily
SH06_RS01695	COG0477	Major facilitator Superfamily
SH06_RS01700	COG3833	ABC-type maltose transport systems, permease component
SH06_RS01705	COG1175	transmembrane transport
SH06_RS01710	COG2182	Extracellular solute-binding protein
SH06_RS01720	COG3842	ATPase activity
SH06_RS01740	COG1357	PFAM Pentapeptide repeats (8 copies)
SH06_RS01760	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SH06_RS01770	COG0534	Mate efflux family protein
SH06_RS01775	COG3237	CsbD-like
SH06_RS01780	COG0735	belongs to the Fur family
SH06_RS01795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SH06_RS01805	COG0604	alcohol dehydrogenase
SH06_RS01810	COG0305	Participates in initiation and elongation during chromosome replication
SH06_RS01815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SH06_RS01820	COG1448	Aminotransferase
SH06_RS01830	COG3700	Belongs to the class B bacterial acid phosphatase family
SH06_RS01835	COG0432	Pfam Uncharacterised protein family UPF0047
SH06_RS01840	COG2315	Protein conserved in bacteria
SH06_RS01845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SH06_RS01850	COG0629	single-stranded DNA binding
SH06_RS01860	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SH06_RS01865	COG2207	Transcriptional regulator
SH06_RS01870	COG0789	Transcriptional regulator
SH06_RS01875	COG2252	PERMEase
SH06_RS01880	COG0025	NhaP-type Na H and K H
SH06_RS01895	COG3162	membrane
SH06_RS01900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SH06_RS01910	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
SH06_RS01915	COG0437	4 iron, 4 sulfur cluster binding
SH06_RS01920	COG3301	Polysulphide reductase, NrfD
SH06_RS01925	COG1138	Cytochrome C-type biogenesis protein
SH06_RS01930	COG3088	subunit of a heme lyase
SH06_RS01935	COG4235	cytochrome complex assembly
SH06_RS01940	COG1301	dicarboxylic acid transport
SH06_RS01945	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SH06_RS01950	COG3383	formate dehydrogenase (NAD+) activity
SH06_RS01955	COG3383	formate dehydrogenase (NAD+) activity
SH06_RS01960	COG1538	Outer membrane efflux protein
SH06_RS01965	COG1289	transmembrane transporter activity
SH06_RS01970	COG1566	PFAM secretion protein HlyD family protein
SH06_RS01980	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SH06_RS01985	COG1940	carbohydrate kinase activity
SH06_RS01990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SH06_RS01995	COG1172	Belongs to the binding-protein-dependent transport system permease family
SH06_RS02000	COG1129	ABC transporter
SH06_RS02005	COG1879	ABC-type sugar transport system periplasmic component
SH06_RS02010	COG1737	Transcriptional regulator
SH06_RS02015	COG0698	ribose 5-phosphate isomerase
SH06_RS02025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SH06_RS02030	COG0456	acetyltransferase
SH06_RS02035	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
SH06_RS02040	COG3454	Phosphonate metabolism
SH06_RS02045	COG4778	phosphonate C-P lyase system protein PhnL
SH06_RS02050	COG4107	phosphonate C-P lyase system protein PhnK
SH06_RS02055	COG3627	carbon phosphorus lyase activity
SH06_RS02060	COG3626	phosphonate metabolism
SH06_RS02065	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
SH06_RS02070	COG3624	Phosphonate C-P lyase system protein PhnG
SH06_RS02075	COG2188	Transcriptional regulator
SH06_RS02085	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SH06_RS02090	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SH06_RS02095	COG2764	glyoxalase bleomycin resistance protein dioxygenase
SH06_RS02100	COG2824	Alkylphosphonate utilization operon protein PhnA
SH06_RS02105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SH06_RS02115	COG0477	Major facilitator Superfamily
SH06_RS02125	COG0642	Histidine kinase
SH06_RS02130	COG0745	RESPONSE REGULATOR receiver
SH06_RS02135	COG2194	sulfuric ester hydrolase activity
SH06_RS02140	COG0531	amino acid
SH06_RS02145	COG2207	Transcriptional regulator
SH06_RS02150	COG1982	Orn Lys Arg decarboxylase major
SH06_RS02155	COG2169	Transcriptional regulator
SH06_RS02165	COG1486	melibiose metabolic process
SH06_RS02170	COG2211	Major facilitator Superfamily
SH06_RS02175	COG3647	Membrane
SH06_RS02180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SH06_RS02180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SH06_RS02185	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SH06_RS02195	COG4565	transcriptional regulatory protein
SH06_RS02200	COG3290	protein histidine kinase activity
SH06_RS02205	COG3592	Divergent 4Fe-4S mono-cluster
SH06_RS02210	COG2388	GCN5-related N-acetyl-transferase
SH06_RS02225	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SH06_RS02230	COG3104	oligopeptide transport
SH06_RS02235	COG1982	Orn Lys Arg decarboxylase major
SH06_RS02240	COG0531	amino acid
SH06_RS02245	COG3710	Transcriptional regulator
SH06_RS02255	COG1309	transcriptional regulator
SH06_RS02260	COG4232	protein-disulfide reductase activity
SH06_RS02270	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SH06_RS02275	COG1027	Aspartate ammonia-lyase
SH06_RS02280	COG3030	protein affecting phage T7 exclusion by the F plasmid
SH06_RS02285	COG0531	amino acid
SH06_RS02310	COG1509	lysine 2,3-aminomutase activity
SH06_RS02320	COG5510	response to toxic substance
SH06_RS02325	COG5510	response to toxic substance
SH06_RS02330	COG2076	Multidrug Resistance protein
SH06_RS02335	COG3040	lipid binding
SH06_RS02340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SH06_RS02355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SH06_RS02360	COG1053	succinate dehydrogenase
SH06_RS02370	COG0531	amino acid
SH06_RS02385	COG1511	domain protein
SH06_RS02385	COG3264	Mechanosensitive ion channel
SH06_RS02420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SH06_RS02425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SH06_RS02425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SH06_RS02430	COG0802	atpase or kinase
SH06_RS02435	COG0860	N-Acetylmuramoyl-L-alanine amidase
SH06_RS02455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SH06_RS02460	COG0330	HflC and HflK could
SH06_RS02465	COG0330	HflC and HflK could
SH06_RS02470	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
SH06_RS02485	COG0557	exoribonuclease II activity
SH06_RS02490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SH06_RS02495	COG3789	protein conserved in bacteria
SH06_RS02500	COG1842	Phage shock protein A
SH06_RS02510	COG3766	membrane
SH06_RS02515	COG5463	Belongs to the UPF0441 family
SH06_RS02520	COG0754	glutathionylspermidine amidase activity
SH06_RS02525	COG1960	acyl-CoA dehydrogenase activity
SH06_RS02535	COG3650	response to hydrogen peroxide
SH06_RS02540	COG1073	alpha beta
SH06_RS02555	COG3037	sugar-specific permease SgaT UlaA
SH06_RS02560	COG3414	Phosphotransferase system galactitol-specific IIB component
SH06_RS02565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS02605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SH06_RS02620	COG1309	transcriptional regulator
SH06_RS02625	COG3061	Opacity-associated protein A
SH06_RS02630	COG0545	Peptidyl-prolyl cis-trans isomerase
SH06_RS02635	COG1113	amino acid transport
SH06_RS02645	COG0697	spore germination
SH06_RS02650	COG0702	epimerase
SH06_RS02655	COG1733	regulation of RNA biosynthetic process
SH06_RS02660	COG0737	Belongs to the 5'-nucleotidase family
SH06_RS02665	COG1218	3'(2'),5'-bisphosphate nucleotidase
SH06_RS02675	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
SH06_RS02685	COG1253	flavin adenine dinucleotide binding
SH06_RS02700	COG0729	surface antigen
SH06_RS02705	COG2911	Protein conserved in bacteria
SH06_RS02710	COG2105	PFAM AIG2 family protein
SH06_RS02715	COG2336	PFAM SpoVT AbrB
SH06_RS02720	COG2337	Toxic component of a toxin-antitoxin (TA) module
SH06_RS02725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SH06_RS02730	COG1879	ABC-type sugar transport system periplasmic component
SH06_RS02735	COG1129	ABC transporter
SH06_RS02740	COG1172	Belongs to the binding-protein-dependent transport system permease family
SH06_RS02745	COG1172	Belongs to the binding-protein-dependent transport system permease family
SH06_RS02755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SH06_RS02765	COG0312	modulator of DNA gyrase
SH06_RS02770	COG3783	Cytochrome b(562)
SH06_RS02775	COG0602	queuosine metabolic process
SH06_RS02780	COG1328	CTP reductase activity
SH06_RS02785	COG0366	Alpha amylase catalytic
SH06_RS02790	COG1263	PTS System
SH06_RS02790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS02795	COG1609	Transcriptional regulator
SH06_RS02800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SH06_RS02805	COG0251	oxidation-reduction process
SH06_RS02830	COG0251	oxidation-reduction process
SH06_RS02835	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS02840	COG1309	transcriptional regulator
SH06_RS02845	COG2731	YhcH YjgK YiaL family protein
SH06_RS02855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SH06_RS02860	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
SH06_RS02865	COG0456	acetyltransferase
SH06_RS02870	COG4269	membrane
SH06_RS02875	COG0525	valine-tRNA ligase activity
SH06_RS02880	COG2927	DNA polymerase III (CHI subunit)
SH06_RS02890	COG0795	lipopolysaccharide-transporting ATPase activity
SH06_RS02895	COG0795	lipopolysaccharide-transporting ATPase activity
SH06_RS02900	COG0433	COG0433 Predicted ATPase
SH06_RS02905	COG1609	Transcriptional regulator
SH06_RS02910	COG2610	gluconate transmembrane transporter activity
SH06_RS02915	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS02920	COG1063	alcohol dehydrogenase
SH06_RS02925	COG3265	gluconokinase activity
SH06_RS02930	COG1064	alcohol dehydrogenase
SH06_RS02940	COG0582	viral genome integration into host DNA
SH06_RS03070	COG2801	Transposase and inactivated derivatives
SH06_RS03315	COG3385	transposase activity
SH06_RS03320	COG2814	Major facilitator Superfamily
SH06_RS03325	COG0673	inositol 2-dehydrogenase activity
SH06_RS03345	COG2826	transposase and inactivated derivatives, IS30 family
SH06_RS03360	COG2085	NADP oxidoreductase coenzyme F420-dependent
SH06_RS03365	COG1120	ATPase activity
SH06_RS03370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SH06_RS03375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SH06_RS03380	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SH06_RS03385	COG4772	TonB-dependent receptor
SH06_RS03390	COG3712	iron ion homeostasis
SH06_RS03395	COG1595	DNA-templated transcription, initiation
SH06_RS03415	COG2390	Transcriptional regulator
SH06_RS03425	COG2610	gluconate transmembrane transporter activity
SH06_RS03430	COG0129	dihydroxy-acid dehydratase activity
SH06_RS03435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SH06_RS03440	COG1414	Transcriptional regulator
SH06_RS03445	COG1349	DNA-binding transcription factor activity
SH06_RS03450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SH06_RS03455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS03460	COG0434	BtpA family
SH06_RS03465	COG3775	system Galactitol-specific IIC component
SH06_RS03470	COG3414	Phosphotransferase system galactitol-specific IIB component
SH06_RS03475	COG1363	Peptidase, m42
SH06_RS03480	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SH06_RS03485	COG3153	acetyltransferase
SH06_RS03505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SH06_RS03505	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SH06_RS03515	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
SH06_RS03520	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SH06_RS03535	COG0582	viral genome integration into host DNA
SH06_RS03540	COG4974	Belongs to the 'phage' integrase family
SH06_RS03550	COG3539	Fimbrial protein
SH06_RS03555	COG3539	Fimbrial protein
SH06_RS03560	COG3121	Chaperone
SH06_RS03565	COG3188	usher protein
SH06_RS03570	COG3539	Fimbrial protein
SH06_RS03575	COG3539	Fimbrial protein
SH06_RS03580	COG3539	Fimbrial protein
SH06_RS03585	COG2610	gluconate transmembrane transporter activity
SH06_RS03600	COG0246	Mannitol dehydrogenase
SH06_RS03610	COG2186	Transcriptional regulator
SH06_RS03640	COG0583	DNA-binding transcription factor activity
SH06_RS03645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SH06_RS03650	COG0700	Nucleoside recognition
SH06_RS03655	COG3366	ferrous iron transmembrane transporter activity
SH06_RS03665	COG0477	Major facilitator Superfamily
SH06_RS03670	COG3204	pilus organization
SH06_RS03680	COG1924	4 iron, 4 sulfur cluster binding
SH06_RS03685	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
SH06_RS03690	COG2733	membrane
SH06_RS03695	COG2814	Major facilitator Superfamily
SH06_RS03705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SH06_RS03710	COG5457	Domain of unknown function (DUF1127)
SH06_RS03715	COG1196	nuclear chromosome segregation
SH06_RS03725	COG4268	DNA restriction-modification system
SH06_RS03730	COG1401	restriction endodeoxyribonuclease activity
SH06_RS03740	COG0732	type I restriction modification DNA specificity domain
SH06_RS03745	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SH06_RS03750	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
SH06_RS03765	COG1715	Restriction endonuclease
SH06_RS03770	COG0523	cobalamin synthesis protein
SH06_RS03775	COG2879	small protein
SH06_RS03780	COG1966	Carbon starvation protein
SH06_RS03790	COG0840	transmembrane signaling receptor activity
SH06_RS03795	COG2271	Major facilitator Superfamily
SH06_RS03800	COG1802	Transcriptional regulator
SH06_RS03805	COG1063	alcohol dehydrogenase
SH06_RS03820	COG1484	DNA-dependent DNA replication
SH06_RS03835	COG2966	Psort location CytoplasmicMembrane, score
SH06_RS03840	COG2197	response regulator
SH06_RS03845	COG2197	response regulator
SH06_RS03850	COG4114	ferric iron reductase
SH06_RS03880	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
SH06_RS03885	COG0456	acetyltransferase
SH06_RS03890	COG1011	Hydrolase
SH06_RS03900	COG2823	Periplasmic or secreted lipoprotein
SH06_RS03910	COG4667	esterase of the alpha-beta hydrolase superfamily
SH06_RS03915	COG0084	hydrolase, TatD family'
SH06_RS03920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SH06_RS03925	COG1328	CTP reductase activity
SH06_RS03955	COG3550	peptidyl-serine autophosphorylation
SH06_RS03965	COG3726	membrane protein affecting hemolysin expression
SH06_RS03970	COG0560	Phosphoserine phosphatase
SH06_RS03975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SH06_RS03980	COG3172	ATPase kinase involved in NAD metabolism
SH06_RS03980	COG1056	cytidyltransferase-related domain
SH06_RS03990	COG0488	(ABC) transporter
SH06_RS03995	COG0741	lytic transglycosylase activity
SH06_RS04015	COG3708	Transcriptional regulator
SH06_RS04015	COG2207	Transcriptional regulator
SH06_RS04020	COG3045	CreA protein
SH06_RS04025	COG0745	RESPONSE REGULATOR receiver
SH06_RS04030	COG2205	protein histidine kinase activity
SH06_RS04035	COG4452	Inner membrane protein CreD
SH06_RS04040	COG0745	RESPONSE REGULATOR receiver
SH06_RS04050	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SH06_RS04060	COG0527	aspartate kinase activity
SH06_RS04060	COG0460	homoserine dehydrogenase
SH06_RS04070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SH06_RS04090	COG1115	amino acid carrier protein
SH06_RS04095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SH06_RS04100	COG0521	Mo-molybdopterin cofactor biosynthetic process
SH06_RS04105	COG1584	GPR1 FUN34 yaaH family protein
SH06_RS04110	COG4735	regulation of single-species biofilm formation
SH06_RS04130	COG3385	transposase activity
SH06_RS04140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SH06_RS04145	COG0583	DNA-binding transcription factor activity
SH06_RS04170	COG0196	riboflavin kinase activity
SH06_RS04185	COG1047	Peptidyl-prolyl cis-trans
SH06_RS04215	COG0505	Belongs to the CarA family
SH06_RS04220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SH06_RS04275	COG0644	oxidoreductase
SH06_RS04280	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SH06_RS04285	COG2271	Major facilitator Superfamily
SH06_RS04300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SH06_RS04325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SH06_RS04330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SH06_RS04335	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SH06_RS04345	COG0564	pseudouridine synthase activity
SH06_RS04355	COG0417	DNA replication proofreading
SH06_RS04360	COG0235	Class ii aldolase
SH06_RS04365	COG2160	L-arabinose isomerase activity
SH06_RS04370	COG1069	ribulokinase activity
SH06_RS04375	COG4977	sequence-specific DNA binding
SH06_RS04380	COG0586	Pfam SNARE associated Golgi protein
SH06_RS04385	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SH06_RS04390	COG1178	ABC-type Fe3 transport system permease component
SH06_RS04395	COG4143	(ABC) transporter
SH06_RS04400	COG4533	DNA binding
SH06_RS04410	COG2814	Major facilitator Superfamily
SH06_RS04425	COG0473	3-isopropylmalate dehydrogenase activity
SH06_RS04440	COG0583	DNA-binding transcription factor activity
SH06_RS04445	COG0028	Belongs to the TPP enzyme family
SH06_RS04450	COG0440	acetolactate synthase activity
SH06_RS04460	COG1609	Transcriptional regulator
SH06_RS04465	COG2001	Belongs to the MraZ family
SH06_RS04475	COG3116	cell division
SH06_RS04480	COG0768	penicillin binding
SH06_RS04485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SH06_RS04490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SH06_RS04500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SH06_RS04505	COG0772	Belongs to the SEDS family
SH06_RS04520	COG1181	Belongs to the D-alanine--D-alanine ligase family
SH06_RS04525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SH06_RS04530	COG0849	cell division
SH06_RS04535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SH06_RS04555	COG0494	nUDIX hydrolase
SH06_RS04575	COG0237	dephospho-CoA kinase activity
SH06_RS04585	COG1459	type II secretion system
SH06_RS04590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SH06_RS04595	COG4969	Belongs to the N-Me-Phe pilin family
SH06_RS04605	COG0157	Belongs to the NadC ModD family
SH06_RS04610	COG3023	N-Acetylmuramoyl-L-alanine amidase
SH06_RS04615	COG3725	Membrane protein required for beta-lactamase induction
SH06_RS04620	COG1113	amino acid transport
SH06_RS04625	COG2186	Transcriptional regulator
SH06_RS04630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SH06_RS04635	COG0508	dehydrogenase complex catalyzes the overall conversion of
SH06_RS04640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SH06_RS04645	COG3064	Membrane
SH06_RS04650	COG1049	propionate catabolic process, 2-methylcitrate cycle
SH06_RS04675	COG2132	Multicopper oxidase
SH06_RS04680	COG4993	Dehydrogenase
SH06_RS04685	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SH06_RS04690	COG0288	reversible hydration of carbon dioxide
SH06_RS04695	COG1131	(ABC) transporter
SH06_RS04700	COG0842	Transport permease protein
SH06_RS04705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS04710	COG0726	polysaccharide deacetylase
SH06_RS04720	COG5464	transposase or invertase
SH06_RS04735	COG3539	Fimbrial protein
SH06_RS04740	COG3539	Fimbrial protein
SH06_RS04745	COG3539	Fimbrial protein
SH06_RS04750	COG3539	Fimbrial protein
SH06_RS04755	COG3188	usher protein
SH06_RS04760	COG3121	Chaperone
SH06_RS04765	COG3539	Fimbrial protein
SH06_RS04770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SH06_RS04775	COG0617	tRNA 3'-terminal CCA addition
SH06_RS04785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SH06_RS04795	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SH06_RS04800	COG1643	Atp-dependent helicase
SH06_RS04810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SH06_RS04815	COG4774	siderophore transport
SH06_RS04820	COG1120	ATPase activity
SH06_RS04825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SH06_RS04830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SH06_RS04850	COG2860	membrane
SH06_RS04855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SH06_RS04870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SH06_RS04875	COG3835	regulator
SH06_RS04885	COG1408	metallophosphoesterase
SH06_RS04900	COG0024	Methionine aminopeptidase
SH06_RS04925	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SH06_RS04930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SH06_RS04935	COG0575	Belongs to the CDS family
SH06_RS04940	COG0750	zinc metalloprotease
SH06_RS04950	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
SH06_RS04955	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SH06_RS04980	COG0587	DNA-directed DNA polymerase activity
SH06_RS04990	COG1982	Orn Lys Arg decarboxylase major
SH06_RS04995	COG0346	lactoylglutathione lyase activity
SH06_RS05000	COG0037	tRNA processing
SH06_RS05005	COG4568	rho-dependent transcription termination
SH06_RS05015	COG4681	YaeQ
SH06_RS05020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SH06_RS05025	COG3015	lipoprotein NlpE involved in copper resistance
SH06_RS05030	COG0791	NLP P60 protein
SH06_RS05040	COG1720	tRNA m6t6A37 methyltransferase activity
SH06_RS05050	COG1464	Belongs to the NlpA lipoprotein family
SH06_RS05055	COG2011	ABC-type metal ion transport system permease component
SH06_RS05060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SH06_RS05065	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SH06_RS05100	COG0656	L-ascorbic acid biosynthetic process
SH06_RS05105	COG0583	DNA-binding transcription factor activity
SH06_RS05115	COG2226	methyltransferase
SH06_RS05120	COG0741	lytic transglycosylase activity
SH06_RS05120	COG1388	LysM domain
SH06_RS05130	COG2226	methyltransferase
SH06_RS05140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SH06_RS05160	COG4104	PAAR repeat-containing protein
SH06_RS05165	COG5433	transposase activity
SH06_RS05170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SH06_RS05180	COG1960	acyl-CoA dehydrogenase activity
SH06_RS05190	COG0121	glutamine amidotransferase
SH06_RS05195	COG3034	peptidoglycan biosynthetic process
SH06_RS05200	COG3041	Addiction module toxin RelE StbE family
SH06_RS05205	COG3077	Addiction module antitoxin, RelB DinJ family
SH06_RS05210	COG0791	NLP P60 protein
SH06_RS05215	COG1943	Transposase
SH06_RS05235	COG2161	toxin-antitoxin pair type II binding
SH06_RS05245	COG0454	-acetyltransferase
SH06_RS05250	COG1690	Belongs to the RtcB family
SH06_RS05255	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SH06_RS05260	COG2195	Cleaves the N-terminal amino acid of tripeptides
SH06_RS05280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SH06_RS05310	COG2003	Belongs to the UPF0758 family
SH06_RS05330	COG2378	regulation of single-species biofilm formation
SH06_RS05345	COG3596	GTP binding
SH06_RS05350	COG0583	DNA-binding transcription factor activity
SH06_RS05355	COG2963	transposase activity
SH06_RS05360	COG2826	transposase and inactivated derivatives, IS30 family
SH06_RS05365	COG2801	Transposase and inactivated derivatives
SH06_RS05380	COG3344	reverse transcriptase
SH06_RS05390	COG0833	amino acid
SH06_RS05395	COG2040	homocysteine
SH06_RS05400	COG3842	ATPase activity
SH06_RS05405	COG1178	ABC-type Fe3 transport system permease component
SH06_RS05410	COG1662	PFAM IS1 transposase
SH06_RS05415	COG3677	Transposase
SH06_RS05415	COG1662	PFAM IS1 transposase
SH06_RS05420	COG2963	transposase activity
SH06_RS05430	COG3415	Transposase
SH06_RS05430	COG2801	Transposase and inactivated derivatives
SH06_RS05435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SH06_RS05440	COG0129	dihydroxy-acid dehydratase activity
SH06_RS05445	COG2211	Major facilitator Superfamily
SH06_RS05450	COG3507	Belongs to the glycosyl hydrolase 43 family
SH06_RS05455	COG1414	Transcriptional regulator
SH06_RS05460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SH06_RS05465	COG1662	PFAM IS1 transposase
SH06_RS05470	COG1061	Type III restriction enzyme res subunit
SH06_RS05480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SH06_RS05500	COG0582	viral genome integration into host DNA
SH06_RS05510	COG0583	DNA-binding transcription factor activity
SH06_RS05515	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SH06_RS05520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SH06_RS05525	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SH06_RS05530	COG2080	2 iron, 2 sulfur cluster binding
SH06_RS05535	COG3477	response to acidic pH
SH06_RS05540	COG0727	PFAM Uncharacterised protein family (UPF0153)
SH06_RS05545	COG3121	Chaperone
SH06_RS05555	COG3188	usher protein
SH06_RS05595	COG1388	LysM domain
SH06_RS05605	COG2801	Transposase and inactivated derivatives
SH06_RS05610	COG2207	Transcriptional regulator
SH06_RS05610	COG3708	Transcriptional regulator
SH06_RS05615	COG3059	membrane
SH06_RS05625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SH06_RS05630	COG2207	Transcriptional regulator
SH06_RS05635	COG0247	lactate metabolic process
SH06_RS05640	COG1139	Iron-sulfur cluster binding protein
SH06_RS05645	COG1556	Lactate utilization protein
SH06_RS05675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SH06_RS05685	COG2200	EAL domain
SH06_RS05685	COG2771	luxR family
SH06_RS05690	COG0583	DNA-binding transcription factor activity
SH06_RS05700	COG0666	response to abiotic stimulus
SH06_RS05710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SH06_RS05715	COG1304	FMN binding
SH06_RS05725	COG0549	Belongs to the carbamate kinase family
SH06_RS05730	COG0402	S-adenosylhomocysteine deaminase activity
SH06_RS05735	COG1064	alcohol dehydrogenase
SH06_RS05750	COG1280	lysine exporter protein (LysE YggA)
SH06_RS05760	COG3829	transcription factor binding
SH06_RS05765	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SH06_RS05770	COG0372	Belongs to the citrate synthase family
SH06_RS05780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SH06_RS05785	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SH06_RS05790	COG0402	S-adenosylhomocysteine deaminase activity
SH06_RS05795	COG0583	DNA-binding transcription factor activity
SH06_RS05800	COG0288	reversible hydration of carbon dioxide
SH06_RS05810	COG2807	transmembrane transport
SH06_RS05815	COG0110	maltose O-acetyltransferase activity
SH06_RS05820	COG2223	nitrite transmembrane transporter activity
SH06_RS05825	COG3250	beta-galactosidase activity
SH06_RS05830	COG1609	Transcriptional regulator
SH06_RS05835	COG1414	Transcriptional regulator
SH06_RS05855	COG3971	2-oxopent-4-enoate hydratase activity
SH06_RS05870	COG2814	Major facilitator Superfamily
SH06_RS05875	COG3122	Protein conserved in bacteria
SH06_RS05885	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SH06_RS05915	COG1215	transferase activity, transferring glycosyl groups
SH06_RS05920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SH06_RS05925	COG4521	taurine ABC transporter
SH06_RS05935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SH06_RS05940	COG2175	clavaminate synthase activity
SH06_RS05945	COG0113	porphobilinogen synthase activity
SH06_RS05955	COG2801	Transposase and inactivated derivatives
SH06_RS05965	COG3468	outer membrane autotransporter barrel domain protein
SH06_RS05970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SH06_RS05975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SH06_RS05985	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
SH06_RS06005	COG1181	Belongs to the D-alanine--D-alanine ligase family
SH06_RS06020	COG1785	Belongs to the alkaline phosphatase family
SH06_RS06030	COG3706	GGDEF domain
SH06_RS06035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SH06_RS06060	COG4126	flavin adenine dinucleotide binding
SH06_RS06080	COG1940	carbohydrate kinase activity
SH06_RS06085	COG2814	Major facilitator Superfamily
SH06_RS06090	COG0419	ATPase involved in DNA repair
SH06_RS06095	COG0420	3'-5' exonuclease activity
SH06_RS06100	COG0745	RESPONSE REGULATOR receiver
SH06_RS06105	COG5002	protein histidine kinase activity
SH06_RS06110	COG1114	Component of the transport system for branched-chain amino acids
SH06_RS06115	COG1113	amino acid transport
SH06_RS06120	COG0366	Alpha amylase catalytic
SH06_RS06140	COG1862	Preprotein translocase
SH06_RS06145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SH06_RS06150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SH06_RS06155	COG1403	HNH endonuclease
SH06_RS06165	COG3248	Nucleoside-binding outer membrane protein
SH06_RS06170	COG4238	major outer membrane lipoprotein
SH06_RS06180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SH06_RS06180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SH06_RS06195	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SH06_RS06200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SH06_RS06205	COG0667	Aldo Keto reductase
SH06_RS06215	COG0142	geranyltranstransferase activity
SH06_RS06230	COG0693	protein deglycase activity
SH06_RS06235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SH06_RS06245	COG2814	Major facilitator Superfamily
SH06_RS06255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SH06_RS06260	COG1845	cytochrome c oxidase, subunit III
SH06_RS06265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SH06_RS06270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SH06_RS06275	COG2223	nitrite transmembrane transporter activity
SH06_RS06280	COG3056	Lipoprotein
SH06_RS06285	COG0271	Belongs to the BolA IbaG family
SH06_RS06310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SH06_RS06315	COG0776	regulation of translation
SH06_RS06320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SH06_RS06325	COG1555	photosystem II stabilization
SH06_RS06330	COG0824	Thioesterase
SH06_RS06340	COG4533	DNA binding
SH06_RS06350	COG1522	sequence-specific DNA binding
SH06_RS06355	COG1132	(ABC) transporter
SH06_RS06360	COG1132	(ABC) transporter
SH06_RS06365	COG0347	Belongs to the P(II) protein family
SH06_RS06370	COG0004	ammonium transporteR
SH06_RS06375	COG1946	Acyl-CoA thioesterase
SH06_RS06380	COG3126	Type III secretion system lipoprotein chaperone (YscW)
SH06_RS06385	COG3695	enzyme binding
SH06_RS06390	COG5507	3-demethylubiquinone-9 3-methyltransferase
SH06_RS06395	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SH06_RS06405	COG0110	maltose O-acetyltransferase activity
SH06_RS06420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SH06_RS06425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SH06_RS06430	COG1309	transcriptional regulator
SH06_RS06435	COG1196	nuclear chromosome segregation
SH06_RS06435	COG3264	Mechanosensitive ion channel
SH06_RS06450	COG3923	Primosomal replication protein n
SH06_RS06455	COG2832	Protein of unknown function (DUF454)
SH06_RS06465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SH06_RS06500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SH06_RS06505	COG4651	solute:proton antiporter activity
SH06_RS06505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SH06_RS06510	COG2223	nitrite transmembrane transporter activity
SH06_RS06515	COG0737	Belongs to the 5'-nucleotidase family
SH06_RS06520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SH06_RS06525	COG3735	TraB family
SH06_RS06530	COG3093	addiction module antidote protein HigA
SH06_RS06535	COG2217	Heavy metal translocating P-type atpase
SH06_RS06540	COG2066	Belongs to the glutaminase family
SH06_RS06545	COG0531	amino acid
SH06_RS06550	COG0789	Transcriptional regulator
SH06_RS06555	COG1585	Membrane protein implicated in regulation of membrane protease activity
SH06_RS06560	COG0330	HflC and HflK could
SH06_RS06565	COG4619	ABC transporter
SH06_RS06570	COG0390	transport system, permease component
SH06_RS06575	COG3118	belongs to the thioredoxin family
SH06_RS06580	COG0300	oxidoreductase activity
SH06_RS06585	COG2755	lipolytic protein G-D-S-L family
SH06_RS06590	COG4181	ATPase activity
SH06_RS06595	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
SH06_RS06600	COG3209	COG3209 Rhs family protein
SH06_RS06610	COG3209	COG3209 Rhs family protein
SH06_RS06620	COG2801	Transposase and inactivated derivatives
SH06_RS06630	COG0583	DNA-binding transcription factor activity
SH06_RS06640	COG1414	Transcriptional regulator
SH06_RS06645	COG3960	tartronate-semialdehyde synthase activity
SH06_RS06650	COG3622	Belongs to the hyi family
SH06_RS06655	COG2084	Dehydrogenase
SH06_RS06660	COG1953	Uracil, thiamine, allantoin
SH06_RS06670	COG2233	PERMEase
SH06_RS06675	COG1929	Belongs to the glycerate kinase type-1 family
SH06_RS06680	COG3257	ureidoglycine aminohydrolase activity
SH06_RS06685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SH06_RS06690	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SH06_RS06695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SH06_RS06700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SH06_RS06710	COG0549	Belongs to the carbamate kinase family
SH06_RS06715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SH06_RS06720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SH06_RS06730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SH06_RS06740	COG1988	membrane-bound metal-dependent
SH06_RS06745	COG2501	S4 domain
SH06_RS06755	COG3539	Fimbrial protein
SH06_RS06760	COG3121	Chaperone
SH06_RS06765	COG3188	usher protein
SH06_RS06770	COG3539	Fimbrial protein
SH06_RS06775	COG3539	Fimbrial protein
SH06_RS06780	COG2197	response regulator
SH06_RS06790	COG0582	viral genome integration into host DNA
SH06_RS06815	COG2801	Transposase and inactivated derivatives
SH06_RS06825	COG2076	Multidrug Resistance protein
SH06_RS06835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SH06_RS06840	COG1881	PFAM PEBP family protein
SH06_RS06845	COG2207	Transcriptional regulator
SH06_RS06900	COG3772	lysozyme
SH06_RS06920	COG5562	phage envelope protein
SH06_RS06940	COG4220	transposase activity
SH06_RS06950	COG0500	methyltransferase
SH06_RS06960	COG2207	Transcriptional regulator
SH06_RS06965	COG4571	Outer membrane protease
SH06_RS06975	COG2207	Transcriptional regulator
SH06_RS06985	COG4783	chaperone-mediated protein folding
SH06_RS06990	COG1215	transferase activity, transferring glycosyl groups
SH06_RS06995	COG5002	protein histidine kinase activity
SH06_RS07000	COG0745	RESPONSE REGULATOR receiver
SH06_RS07005	COG1538	Outer membrane efflux protein
SH06_RS07010	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SH06_RS07015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SH06_RS07020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SH06_RS07025	COG1113	amino acid transport
SH06_RS07030	COG0668	transmembrane transport
SH06_RS07035	COG0778	Nitroreductase
SH06_RS07040	COG2315	Protein conserved in bacteria
SH06_RS07065	COG3385	transposase activity
SH06_RS07070	COG2977	Belongs to the P-Pant transferase superfamily
SH06_RS07075	COG4771	TonB-dependent receptor
SH06_RS07080	COG2382	esterase
SH06_RS07085	COG3251	PFAM MbtH domain protein
SH06_RS07090	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SH06_RS07090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SH06_RS07095	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
SH06_RS07100	COG1120	ATPase activity
SH06_RS07105	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SH06_RS07110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SH06_RS07120	COG4592	Periplasmic binding protein
SH06_RS07125	COG1169	isochorismate synthase
SH06_RS07130	COG1021	2,3-dihydroxybenzoate-AMP ligase
SH06_RS07135	COG3433	isochorismatase activity
SH06_RS07135	COG1535	isochorismatase
SH06_RS07140	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS07145	COG2050	protein possibly involved in aromatic compounds catabolism
SH06_RS07150	COG1966	Carbon starvation protein
SH06_RS07155	COG2879	small protein
SH06_RS07160	COG0371	Dehydrogenase
SH06_RS07165	COG0436	Aminotransferase
SH06_RS07170	COG1475	DNA binding
SH06_RS07175	COG3969	phosphoadenosine phosphosulfate
SH06_RS07180	COG0583	DNA-binding transcription factor activity
SH06_RS07185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SH06_RS07190	COG0450	alkyl hydroperoxide reductase
SH06_RS07195	COG3634	alkyl hydroperoxide reductase activity
SH06_RS07200	COG0589	response to stress
SH06_RS07205	COG1063	alcohol dehydrogenase
SH06_RS07215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SH06_RS07220	COG3719	Belongs to the RNase T2 family
SH06_RS07225	COG0471	metal ion transport
SH06_RS07240	COG3051	citrate lyase alpha subunit
SH06_RS07245	COG2301	Belongs to the HpcH HpaI aldolase family
SH06_RS07255	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SH06_RS07260	COG3290	protein histidine kinase activity
SH06_RS07265	COG4565	transcriptional regulatory protein
SH06_RS07270	COG3069	C4-dicarboxylate transmembrane transporter activity
SH06_RS07295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SH06_RS07305	COG0583	DNA-binding transcription factor activity
SH06_RS07325	COG1686	Belongs to the peptidase S11 family
SH06_RS07330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SH06_RS07335	COG0772	Belongs to the SEDS family
SH06_RS07340	COG0768	penicillin binding
SH06_RS07350	COG0799	negative regulation of ribosome biogenesis
SH06_RS07355	COG0406	alpha-ribazole phosphatase activity
SH06_RS07365	COG1466	dna polymerase III delta subunit
SH06_RS07380	COG2888	peptidyl-tyrosine sulfation
SH06_RS07385	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SH06_RS07395	COG2214	Heat shock protein DnaJ domain protein
SH06_RS07400	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SH06_RS07410	COG2214	Heat shock protein DnaJ domain protein
SH06_RS07415	COG0443	Heat shock 70 kDa protein
SH06_RS07425	COG1126	abc transporter atp-binding protein
SH06_RS07430	COG0765	amino acid transport
SH06_RS07435	COG0765	amino acid transport
SH06_RS07440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SH06_RS07450	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SH06_RS07455	COG4535	Mg2 and Co2 transporter CorC
SH06_RS07465	COG1702	phosphate starvation-inducible protein PhoH
SH06_RS07475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SH06_RS07515	COG0367	asparagine synthase
SH06_RS07520	COG0647	UMP catabolic process
SH06_RS07525	COG1846	Transcriptional regulator
SH06_RS07525	COG1940	carbohydrate kinase activity
SH06_RS07530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SH06_RS07540	COG1263	PTS System
SH06_RS07540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS07540	COG2190	(PTS) system
SH06_RS07560	COG0735	belongs to the Fur family
SH06_RS07575	COG0716	FMN binding
SH06_RS07585	COG0596	Alpha beta hydrolase
SH06_RS07590	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
SH06_RS07595	COG0033	Phosphoglucomutase
SH06_RS07615	COG0531	amino acid
SH06_RS07620	COG1982	Orn Lys Arg decarboxylase major
SH06_RS07630	COG0745	RESPONSE REGULATOR receiver
SH06_RS07635	COG2205	protein histidine kinase activity
SH06_RS07665	COG3209	COG3209 Rhs family protein
SH06_RS07675	COG3209	COG3209 Rhs family protein
SH06_RS07685	COG5433	transposase activity
SH06_RS07695	COG5433	transposase activity
SH06_RS07700	COG3272	Protein of unknown function (DUF1722)
SH06_RS07705	COG0415	Belongs to the DNA photolyase family
SH06_RS07710	COG3104	oligopeptide transport
SH06_RS07715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SH06_RS07720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SH06_RS07725	COG1984	allophanate hydrolase subunit 2
SH06_RS07740	COG3180	Ammonia monooxygenase
SH06_RS07745	COG3539	Fimbrial protein
SH06_RS07750	COG3121	Chaperone
SH06_RS07755	COG3188	usher protein
SH06_RS07760	COG3539	Fimbrial protein
SH06_RS07765	COG0372	Belongs to the citrate synthase family
SH06_RS07775	COG2009	succinate dehydrogenase
SH06_RS07780	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
SH06_RS07785	COG1053	succinate dehydrogenase
SH06_RS07790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SH06_RS07800	COG0567	Dehydrogenase, E1 component
SH06_RS07805	COG0508	dehydrogenase complex catalyzes the overall conversion of
SH06_RS07815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SH06_RS07820	COG2188	Transcriptional regulator
SH06_RS07825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS07825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS07825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS07830	COG0383	alpha-mannosidase activity
SH06_RS07840	COG1271	oxidase subunit
SH06_RS07845	COG1294	oxidase, subunit
SH06_RS07850	COG4890	Cyd operon protein YbgT
SH06_RS07855	COG3790	cyd operon protein YbgE
SH06_RS07860	COG0824	Thioesterase
SH06_RS07865	COG0811	peptide transport
SH06_RS07870	COG0848	biopolymer transport protein
SH06_RS07875	COG3064	Membrane
SH06_RS07885	COG2885	chlorophyll binding
SH06_RS07890	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
SH06_RS07935	COG3201	nicotinamide mononucleotide transporter
SH06_RS07940	COG1230	cation diffusion facilitator family transporter
SH06_RS07955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SH06_RS07965	COG2017	converts alpha-aldose to the beta-anomer
SH06_RS07975	COG1085	galactose-1-phosphate uridylyltransferase
SH06_RS07980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SH06_RS07985	COG1119	ATPase activity
SH06_RS07990	COG2005	Transcriptional regulator
SH06_RS07990	COG3585	molybdate ion transport
SH06_RS08000	COG0725	ABC transporter, periplasmic molybdate-binding protein
SH06_RS08005	COG4149	molybdate abc transporter
SH06_RS08010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SH06_RS08015	COG0561	phosphatase activity
SH06_RS08025	COG0583	DNA-binding transcription factor activity
SH06_RS08030	COG2828	Protein conserved in bacteria
SH06_RS08035	COG0471	metal ion transport
SH06_RS08040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SH06_RS08045	COG4677	pectinesterase activity
SH06_RS08050	COG1881	PFAM PEBP family protein
SH06_RS08055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SH06_RS08070	COG2226	methyltransferase
SH06_RS08075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SH06_RS08085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SH06_RS08100	COG0521	Mo-molybdopterin cofactor biosynthetic process
SH06_RS08110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SH06_RS08115	COG0314	molybdopterin synthase activity
SH06_RS08120	COG0670	Belongs to the BI1 family
SH06_RS08125	COG0670	Belongs to the BI1 family
SH06_RS08130	COG0392	lysyltransferase activity
SH06_RS08135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SH06_RS08140	COG3568	Endonuclease Exonuclease Phosphatase
SH06_RS08150	COG0842	Transport permease protein
SH06_RS08155	COG0842	Transport permease protein
SH06_RS08160	COG1131	(ABC) transporter
SH06_RS08170	COG1309	transcriptional regulator
SH06_RS08175	COG0513	Belongs to the DEAD box helicase family
SH06_RS08180	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
SH06_RS08185	COG1199	ATP-dependent helicase activity
SH06_RS08190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SH06_RS08195	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SH06_RS08205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SH06_RS08215	COG4774	siderophore transport
SH06_RS08230	COG0668	transmembrane transport
SH06_RS08235	COG1126	abc transporter atp-binding protein
SH06_RS08240	COG0765	amino acid transport
SH06_RS08245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SH06_RS08260	COG5006	permease, DMT superfamily
SH06_RS08265	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
SH06_RS08270	COG2194	sulfuric ester hydrolase activity
SH06_RS08280	COG1321	iron dependent repressor
SH06_RS08285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SH06_RS08290	COG1376	ErfK ybiS ycfS ynhG family protein
SH06_RS08295	COG0488	(ABC) transporter
SH06_RS08305	COG0561	phosphatase activity
SH06_RS08310	COG1882	Formate acetyltransferase
SH06_RS08315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SH06_RS08320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SH06_RS08325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SH06_RS08330	COG0303	'Molybdopterin
SH06_RS08335	COG1446	asparaginase
SH06_RS08340	COG4172	Belongs to the ABC transporter superfamily
SH06_RS08345	COG0747	negative chemotaxis
SH06_RS08355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SH06_RS08360	COG2200	EAL domain
SH06_RS08365	COG2199	diguanylate cyclase activity
SH06_RS08380	COG2133	pyrroloquinoline quinone binding
SH06_RS08385	COG0625	glutathione transferase activity
SH06_RS08390	COG1686	Belongs to the peptidase S11 family
SH06_RS08395	COG1349	DNA-binding transcription factor activity
SH06_RS08400	COG0671	phosphoesterase, PA-phosphatase related
SH06_RS08405	COG2814	Major facilitator Superfamily
SH06_RS08415	COG0561	phosphatase activity
SH06_RS08420	COG0738	Major facilitator superfamily
SH06_RS08425	COG3226	Transcriptional regulator
SH06_RS08440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SH06_RS08450	COG0778	Nitroreductase
SH06_RS08470	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SH06_RS08475	COG3842	ATPase activity
SH06_RS08480	COG1176	ABC-type spermidine putrescine transport system, permease component I
SH06_RS08485	COG1177	transmembrane transport
SH06_RS08500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SH06_RS08505	COG4160	amino acid transport
SH06_RS08510	COG4215	(ABC) transporter
SH06_RS08515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SH06_RS08520	COG1126	abc transporter atp-binding protein
SH06_RS08535	COG3023	N-Acetylmuramoyl-L-alanine amidase
SH06_RS08540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SH06_RS08545	COG0702	epimerase
SH06_RS08550	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
SH06_RS08555	COG0028	Belongs to the TPP enzyme family
SH06_RS08560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SH06_RS08570	COG2431	L-lysine efflux transmembrane transporter activity
SH06_RS08585	COG3593	DNA synthesis involved in DNA repair
SH06_RS08590	COG2990	Protein conserved in bacteria
SH06_RS08595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SH06_RS08600	COG0577	efflux transmembrane transporter activity
SH06_RS08600	COG1136	(ABC) transporter
SH06_RS08605	COG1278	Cold shock
SH06_RS08615	COG0542	response to heat
SH06_RS08635	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SH06_RS08640	COG4988	ABC transporter
SH06_RS08645	COG0492	ferredoxin-NADP+ reductase activity
SH06_RS08650	COG1522	sequence-specific DNA binding
SH06_RS08655	COG1178	ABC-type Fe3 transport system permease component
SH06_RS08655	COG1674	ftsk spoiiie
SH06_RS08665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SH06_RS08675	COG0243	molybdopterin cofactor binding
SH06_RS08680	COG0437	4 iron, 4 sulfur cluster binding
SH06_RS08685	COG3302	dmso reductase anchor subunit
SH06_RS08690	COG1335	isochorismatase
SH06_RS08700	COG0531	amino acid
SH06_RS08705	COG0583	DNA-binding transcription factor activity
SH06_RS08710	COG2249	NAD(P)H dehydrogenase (quinone) activity
SH06_RS08715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SH06_RS08720	COG1882	Formate acetyltransferase
SH06_RS08725	COG2116	formate transmembrane transporter activity
SH06_RS08730	COG1944	ATP diphosphatase activity
SH06_RS08735	COG2323	membrane
SH06_RS08750	COG0501	Belongs to the peptidase M48B family
SH06_RS08760	COG0539	negative regulation of cytoplasmic translation
SH06_RS08770	COG0658	competence protein
SH06_RS08770	COG2333	competence protein COMEC
SH06_RS08775	COG1132	(ABC) transporter
SH06_RS08785	COG3214	Protein conserved in bacteria
SH06_RS08800	COG3173	Aminoglycoside phosphotransferase
SH06_RS08805	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SH06_RS08810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SH06_RS08820	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
SH06_RS08830	COG2989	Protein conserved in bacteria
SH06_RS08835	COG3108	Peptidase M15
SH06_RS08840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SH06_RS08845	COG1448	Aminotransferase
SH06_RS08870	COG0308	aminopeptidase N
SH06_RS08875	COG1116	anion transmembrane transporter activity
SH06_RS08880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SH06_RS08890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SH06_RS08895	COG0431	NADPH-dependent FMN reductase
SH06_RS08900	COG3539	Fimbrial protein
SH06_RS08905	COG3121	Chaperone
SH06_RS08910	COG3188	usher protein
SH06_RS08915	COG3539	Fimbrial protein
SH06_RS08920	COG3539	Fimbrial protein
SH06_RS08925	COG3539	Fimbrial protein
SH06_RS08930	COG3121	Chaperone
SH06_RS08945	COG3217	Mosc domain protein beta barrel domain protein
SH06_RS08945	COG0633	Ferredoxin
SH06_RS08955	COG0488	(ABC) transporter
SH06_RS08960	COG2995	paraquat-inducible protein a
SH06_RS08965	COG3008	intermembrane lipid transfer
SH06_RS08965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SH06_RS08970	COG3009	Protein conserved in bacteria
SH06_RS08975	COG3130	regulation of translation
SH06_RS08985	COG1067	ATP-dependent peptidase activity
SH06_RS08995	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
SH06_RS08995	COG2885	chlorophyll binding
SH06_RS09010	COG3070	regulator of competence-specific genes
SH06_RS09015	COG1289	transmembrane transporter activity
SH06_RS09020	COG3304	Inner membrane component domain
SH06_RS09025	COG0210	DNA helicase
SH06_RS09045	COG1832	CoA-binding protein
SH06_RS09060	COG1254	Belongs to the acylphosphatase family
SH06_RS09065	COG2920	part of a sulfur-relay system
SH06_RS09070	COG0670	Belongs to the BI1 family
SH06_RS09080	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SH06_RS09085	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SH06_RS09090	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
SH06_RS09095	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SH06_RS09100	COG1999	signal sequence binding
SH06_RS09105	COG1773	rubredoxin
SH06_RS09110	COG1271	oxidase subunit
SH06_RS09115	COG1294	oxidase, subunit
SH06_RS09130	COG3206	protein involved in exopolysaccharide biosynthesis
SH06_RS09130	COG0489	protein tyrosine kinase activity
SH06_RS09135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SH06_RS09140	COG1596	polysaccharide export
SH06_RS09145	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SH06_RS09170	COG1662	PFAM IS1 transposase
SH06_RS09175	COG1278	Cold shock
SH06_RS09180	COG1278	Cold shock
SH06_RS09195	COG0348	domain, Protein
SH06_RS09200	COG2198	Histidine kinase
SH06_RS09200	COG0784	Response regulator, receiver
SH06_RS09200	COG2205	protein histidine kinase activity
SH06_RS09205	COG1879	ABC-type sugar transport system periplasmic component
SH06_RS09210	COG0745	RESPONSE REGULATOR receiver
SH06_RS09215	COG3005	denitrification pathway
SH06_RS09220	COG0243	molybdopterin cofactor binding
SH06_RS09265	COG3729	General stress protein
SH06_RS09270	COG2233	PERMEase
SH06_RS09305	COG1309	transcriptional regulator
SH06_RS09310	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SH06_RS09310	COG0506	proline dehydrogenase activity
SH06_RS09310	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SH06_RS09320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SH06_RS09335	COG2822	iron ion transport
SH06_RS09340	COG2837	iron assimilation
SH06_RS09350	COG1702	phosphate starvation-inducible protein PhoH
SH06_RS09355	COG3658	cytochrome
SH06_RS09360	COG1215	transferase activity, transferring glycosyl groups
SH06_RS09365	COG1649	PFAM Uncharacterised BCR, COG1649
SH06_RS09365	COG0726	polysaccharide deacetylase
SH06_RS09370	COG0457	Tetratricopeptide repeat
SH06_RS09375	COG3706	GGDEF domain
SH06_RS09380	COG2801	Transposase and inactivated derivatives
SH06_RS09420	COG3381	protein complex oligomerization
SH06_RS09430	COG1462	curli production assembly transport component CsgG
SH06_RS09445	COG2197	response regulator
SH06_RS09475	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SH06_RS09480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SH06_RS09505	COG2943	transferase activity, transferring hexosyl groups
SH06_RS09510	COG5645	(Lipo)protein
SH06_RS09530	COG1560	Kdo2-lipid A biosynthetic process
SH06_RS09540	COG2353	YceI-like domain
SH06_RS09545	COG3038	cytochrome b561
SH06_RS09580	COG2999	glutathione oxidoreductase activity
SH06_RS09590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SH06_RS09600	COG0673	inositol 2-dehydrogenase activity
SH06_RS09605	COG0728	peptidoglycan biosynthetic process
SH06_RS09610	COG3418	PFAM FlgN family protein
SH06_RS09615	COG2747	anti-sigma28 factor FlgM
SH06_RS09620	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
SH06_RS09625	COG1815	bacterial-type flagellum-dependent cell motility
SH06_RS09630	COG1558	bacterial-type flagellum-dependent cell motility
SH06_RS09635	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SH06_RS09640	COG1749	Flagellar hook protein flgE
SH06_RS09645	COG4787	bacterial-type flagellum-dependent cell motility
SH06_RS09650	COG4786	Flagellar basal body rod
SH06_RS09665	COG1705	Flagellar rod assembly protein muramidase FlgJ
SH06_RS09665	COG3951	Flagellar rod assembly protein muramidase FlgJ
SH06_RS09670	COG1256	bacterial-type flagellum assembly
SH06_RS09675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SH06_RS09680	COG1530	ribonuclease E activity
SH06_RS09690	COG0564	pseudouridine synthase activity
SH06_RS09695	COG0424	maF-like protein
SH06_RS09700	COG1399	metal-binding, possibly nucleic acid-binding protein
SH06_RS09720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SH06_RS09725	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS09735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SH06_RS09740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SH06_RS09745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SH06_RS09755	COG0470	DNA polymerase III
SH06_RS09760	COG0084	hydrolase, TatD family'
SH06_RS09765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS09765	COG1263	PTS System
SH06_RS09770	COG4773	Receptor
SH06_RS09775	COG0537	adenosine 5'-monophosphoramidase activity
SH06_RS09780	COG5633	Lipoprotein
SH06_RS09785	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
SH06_RS09805	COG1252	NADH dehydrogenase
SH06_RS09810	COG3134	Outer membrane lipoprotein
SH06_RS09815	COG1309	transcriptional regulator
SH06_RS09825	COG1376	ErfK ybiS ycfS ynhG family protein
SH06_RS09825	COG1388	LysM domain
SH06_RS09830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SH06_RS09835	COG4763	Acyl-transferase
SH06_RS09840	COG4591	ABC-type transport system involved in lipoprotein release permease component
SH06_RS09845	COG1136	(ABC) transporter
SH06_RS09850	COG4591	ABC-type transport system involved in lipoprotein release permease component
SH06_RS09860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SH06_RS09865	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
SH06_RS09875	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SH06_RS09880	COG1177	transmembrane transport
SH06_RS09890	COG3842	ATPase activity
SH06_RS09905	COG2850	peptidyl-arginine hydroxylation
SH06_RS09910	COG2205	protein histidine kinase activity
SH06_RS09915	COG0745	RESPONSE REGULATOR receiver
SH06_RS09920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SH06_RS09940	COG1187	pseudouridine synthase activity
SH06_RS09945	COG0538	isocitrate dehydrogenase activity
SH06_RS09960	COG5562	phage envelope protein
SH06_RS09965	COG0789	Transcriptional regulator
SH06_RS09970	COG2200	EAL domain
SH06_RS09995	COG2200	EAL domain
SH06_RS10045	COG2894	cell division
SH06_RS10075	COG0179	Fumarylacetoacetate (FAA) hydrolase
SH06_RS10090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SH06_RS10095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SH06_RS10100	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SH06_RS10115	COG2719	SpoVR family
SH06_RS10125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SH06_RS10135	COG1619	proteins homologs of microcin C7 resistance protein MccF
SH06_RS10145	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
SH06_RS10150	COG2261	transglycosylase associated protein
SH06_RS10165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SH06_RS10165	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SH06_RS10165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS10170	COG1461	Dihydroxyacetone kinase
SH06_RS10175	COG2376	Dihydroxyacetone kinase
SH06_RS10180	COG3284	Transcriptional regulator
SH06_RS10185	COG3468	outer membrane autotransporter barrel domain protein
SH06_RS10195	COG0012	GTP binding
SH06_RS10210	COG0659	secondary active sulfate transmembrane transporter activity
SH06_RS10215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SH06_RS10240	COG2890	protein-(glutamine-N5) methyltransferase activity
SH06_RS10245	COG3094	Invasion gene expression up-regulator, SirB
SH06_RS10250	COG2912	Transglutaminase-like superfamily
SH06_RS10270	COG0387	Pfam Sodium calcium exchanger
SH06_RS10275	COG4572	Cation transport regulator
SH06_RS10280	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
SH06_RS10285	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
SH06_RS10290	COG4932	domain protein
SH06_RS10295	COG2197	response regulator
SH06_RS10300	COG3850	Histidine kinase
SH06_RS10310	COG2223	nitrite transmembrane transporter activity
SH06_RS10315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SH06_RS10320	COG1140	nitrate reductase beta subunit
SH06_RS10325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SH06_RS10330	COG2181	nitrate reductase activity
SH06_RS10350	COG0788	formyltetrahydrofolate deformylase activity
SH06_RS10360	COG1752	Esterase of the alpha-beta hydrolase superfamily
SH06_RS10365	COG0745	RESPONSE REGULATOR receiver
SH06_RS10370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SH06_RS10380	COG1435	thymidine kinase activity
SH06_RS10395	COG1012	belongs to the aldehyde dehydrogenase family
SH06_RS10395	COG1454	alcohol dehydrogenase
SH06_RS10400	COG2095	MarC family integral membrane protein
SH06_RS10405	COG4166	transmembrane transport
SH06_RS10410	COG0601	transmembrane transport
SH06_RS10415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SH06_RS10420	COG0444	Belongs to the ABC transporter superfamily
SH06_RS10425	COG4608	Belongs to the ABC transporter superfamily
SH06_RS10445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SH06_RS10450	COG2350	Protein conserved in bacteria
SH06_RS10455	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
SH06_RS10460	COG1607	acyl-coa hydrolase
SH06_RS10475	COG3047	cAMP biosynthetic process
SH06_RS10480	COG3685	Protein conserved in bacteria
SH06_RS10485	COG3685	Protein conserved in bacteria
SH06_RS10490	COG3729	General stress protein
SH06_RS10505	COG0135	phosphoribosylanthranilate isomerase activity
SH06_RS10505	COG0134	indole-3-glycerol-phosphate synthase activity
SH06_RS10510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SH06_RS10510	COG0512	Glutamine amidotransferase of anthranilate synthase
SH06_RS10515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SH06_RS10520	COG0613	PHP domain protein
SH06_RS10525	COG0009	L-threonylcarbamoyladenylate synthase
SH06_RS10530	COG4907	membrane protein (DUF2207)
SH06_RS10535	COG1187	pseudouridine synthase activity
SH06_RS10540	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SH06_RS10545	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS10555	COG0616	signal peptide processing
SH06_RS10570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SH06_RS10575	COG0583	DNA-binding transcription factor activity
SH06_RS10595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SH06_RS10605	COG0671	phosphoesterase, PA-phosphatase related
SH06_RS10610	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
SH06_RS10615	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
SH06_RS10625	COG0023	Translation Initiation Factor
SH06_RS10635	COG1349	DNA-binding transcription factor activity
SH06_RS10645	COG5001	Diguanylate cyclase
SH06_RS10660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SH06_RS10660	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SH06_RS10665	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SH06_RS10670	COG2852	Protein conserved in bacteria
SH06_RS10675	COG4172	Belongs to the ABC transporter superfamily
SH06_RS10680	COG4172	Belongs to the ABC transporter superfamily
SH06_RS10685	COG4171	peptide transport system, permease
SH06_RS10690	COG4168	peptide transport system, permease
SH06_RS10695	COG4166	transmembrane transport
SH06_RS10710	COG0531	amino acid
SH06_RS10715	COG0174	glutamine synthetase
SH06_RS10720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SH06_RS10725	COG1396	sequence-specific DNA binding
SH06_RS10725	COG1917	Cupin 2, conserved barrel domain protein
SH06_RS10730	COG1012	belongs to the aldehyde dehydrogenase family
SH06_RS10735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SH06_RS10740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SH06_RS10745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SH06_RS10750	COG1842	Phage shock protein A
SH06_RS10760	COG1983	PspC domain protein
SH06_RS10770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SH06_RS10775	COG0366	Alpha amylase catalytic
SH06_RS10780	COG1653	transport
SH06_RS10785	COG1175	transmembrane transport
SH06_RS10790	COG0395	ABC-type sugar transport system, permease component
SH06_RS10795	COG1063	alcohol dehydrogenase
SH06_RS10800	COG1082	Xylose isomerase domain protein TIM barrel
SH06_RS10805	COG0673	inositol 2-dehydrogenase activity
SH06_RS10810	COG1554	hydrolase, family 65, central catalytic
SH06_RS10815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SH06_RS10830	COG1609	Transcriptional regulator
SH06_RS10835	COG3106	COG3106 Predicted ATPase
SH06_RS10845	COG3283	Transcriptional regulator of aromatic amino acids metabolism
SH06_RS10850	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SH06_RS10855	COG4948	Mandelate Racemase Muconate Lactonizing
SH06_RS10860	COG2866	Carboxypeptidase
SH06_RS10865	COG0702	epimerase
SH06_RS10870	COG1073	alpha beta
SH06_RS10875	COG0583	DNA-binding transcription factor activity
SH06_RS10885	COG4166	transmembrane transport
SH06_RS10890	COG0668	transmembrane transport
SH06_RS10900	COG3182	Iron-regulated membrane protein
SH06_RS10905	COG0589	response to stress
SH06_RS10910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SH06_RS10915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SH06_RS10920	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SH06_RS10930	COG1473	amidohydrolase
SH06_RS10935	COG1473	amidohydrolase
SH06_RS10940	COG0583	DNA-binding transcription factor activity
SH06_RS10950	COG2840	Smr protein MutS2
SH06_RS10955	COG3706	GGDEF domain
SH06_RS10970	COG0513	Belongs to the DEAD box helicase family
SH06_RS10980	COG0582	viral genome integration into host DNA
SH06_RS11000	COG3723	Recombinational DNA repair protein, rece pathway
SH06_RS11005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SH06_RS11035	COG4197	protein conserved in bacteria, prophage-related
SH06_RS11045	COG3756	Protein conserved in bacteria
SH06_RS11050	COG1484	DNA-dependent DNA replication
SH06_RS11055	COG1846	Transcriptional regulator
SH06_RS11065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SH06_RS11070	COG1475	DNA binding
SH06_RS11085	COG1196	nuclear chromosome segregation
SH06_RS11095	COG3039	Transposase
SH06_RS11115	COG5301	cellulose 1,4-beta-cellobiosidase activity
SH06_RS11120	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SH06_RS11125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SH06_RS11135	COG0589	response to stress
SH06_RS11140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SH06_RS11145	COG0674	pyruvate-flavodoxin oxidoreductase activity
SH06_RS11145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SH06_RS11145	COG1013	pyruvate-flavodoxin oxidoreductase activity
SH06_RS11145	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SH06_RS11150	COG3042	response to heat
SH06_RS11155	COG3187	Heat shock protein
SH06_RS11160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SH06_RS11165	COG2911	Protein conserved in bacteria
SH06_RS11175	COG3784	Protein of unknown function (DUF1318)
SH06_RS11180	COG2207	Transcriptional regulator
SH06_RS11185	COG1012	belongs to the aldehyde dehydrogenase family
SH06_RS11190	COG3733	amine oxidase
SH06_RS11195	COG1012	belongs to the aldehyde dehydrogenase family
SH06_RS11195	COG2030	dehydratase
SH06_RS11200	COG3396	Phenylacetate-CoA oxygenase
SH06_RS11205	COG3460	Phenylacetate-CoA oxygenase
SH06_RS11210	COG3396	Phenylacetate-CoA oxygenase
SH06_RS11215	COG2151	metal-sulfur cluster biosynthetic enzyme
SH06_RS11220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SH06_RS11225	COG1024	Enoyl-CoA hydratase
SH06_RS11230	COG1024	Enoyl-CoA hydratase
SH06_RS11235	COG1250	3-hydroxyacyl-CoA dehydrogenase
SH06_RS11240	COG2050	protein possibly involved in aromatic compounds catabolism
SH06_RS11245	COG0183	Belongs to the thiolase family
SH06_RS11250	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
SH06_RS11255	COG3327	negative regulation of DNA-templated transcription, initiation
SH06_RS11260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SH06_RS11280	COG2826	transposase and inactivated derivatives, IS30 family
SH06_RS11290	COG0667	Aldo Keto reductase
SH06_RS11300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SH06_RS11305	COG4589	Belongs to the CDS family
SH06_RS11310	COG2267	carboxylic ester hydrolase activity
SH06_RS11315	COG0671	phosphoesterase, PA-phosphatase related
SH06_RS11315	COG2453	phosphatase
SH06_RS11325	COG1643	Atp-dependent helicase
SH06_RS11330	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SH06_RS11335	COG1012	belongs to the aldehyde dehydrogenase family
SH06_RS11340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SH06_RS11345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SH06_RS11350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SH06_RS11355	COG3038	cytochrome b561
SH06_RS11370	COG0840	transmembrane signaling receptor activity
SH06_RS11375	COG0583	DNA-binding transcription factor activity
SH06_RS11380	COG5383	Protein conserved in bacteria
SH06_RS11395	COG2841	Protein conserved in bacteria
SH06_RS11400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SH06_RS11405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SH06_RS11410	COG1275	C4-dicarboxylate transporter malic acid transport protein
SH06_RS11415	COG0500	methyltransferase
SH06_RS11435	COG0675	Transposase, IS605 OrfB family
SH06_RS11440	COG3135	benzoate transporter
SH06_RS11445	COG1396	sequence-specific DNA binding
SH06_RS11450	COG0826	peptidase U32
SH06_RS11460	COG1724	mRNA binding
SH06_RS11465	COG1598	PFAM Uncharacterised protein family UPF0150
SH06_RS11470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SH06_RS11475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SH06_RS11480	COG3842	ATPase activity
SH06_RS11485	COG1176	ABC-type spermidine putrescine transport system, permease component I
SH06_RS11490	COG1177	transmembrane transport
SH06_RS11515	COG3238	Protein conserved in bacteria
SH06_RS11520	COG1247	-acetyltransferase
SH06_RS11525	COG2130	NADP-dependent
SH06_RS11530	COG1802	Transcriptional regulator
SH06_RS11535	COG4772	TonB-dependent receptor
SH06_RS11540	COG3391	amine dehydrogenase activity
SH06_RS11545	COG1113	amino acid transport
SH06_RS11550	COG0625	glutathione transferase activity
SH06_RS11560	COG3209	COG3209 Rhs family protein
SH06_RS11570	COG5433	transposase activity
SH06_RS11575	COG5433	transposase activity
SH06_RS11585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SH06_RS11590	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SH06_RS11595	COG0384	phenazine biosynthesis protein PhzF
SH06_RS11600	COG2181	nitrate reductase activity
SH06_RS11605	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SH06_RS11610	COG1140	nitrate reductase beta subunit
SH06_RS11615	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SH06_RS11620	COG2223	nitrite transmembrane transporter activity
SH06_RS11630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SH06_RS11635	COG0697	spore germination
SH06_RS11640	COG0243	molybdopterin cofactor binding
SH06_RS11640	COG3383	formate dehydrogenase (NAD+) activity
SH06_RS11645	COG0243	molybdopterin cofactor binding
SH06_RS11645	COG3383	formate dehydrogenase (NAD+) activity
SH06_RS11650	COG0437	4 iron, 4 sulfur cluster binding
SH06_RS11655	COG2864	formate dehydrogenase
SH06_RS11660	COG3093	addiction module antidote protein HigA
SH06_RS11665	COG1064	alcohol dehydrogenase
SH06_RS11685	COG1764	response to oxidative stress
SH06_RS11690	COG4608	Belongs to the ABC transporter superfamily
SH06_RS11695	COG0444	Belongs to the ABC transporter superfamily
SH06_RS11700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SH06_RS11705	COG0601	transmembrane transport
SH06_RS11710	COG0747	negative chemotaxis
SH06_RS11715	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SH06_RS11720	COG2199	diguanylate cyclase activity
SH06_RS11720	COG2200	EAL domain
SH06_RS11720	COG2202	Pas domain
SH06_RS11725	COG3706	GGDEF domain
SH06_RS11730	COG1649	PFAM Uncharacterised BCR, COG1649
SH06_RS11735	COG0531	amino acid
SH06_RS11740	COG0076	glutamate decarboxylase activity
SH06_RS11750	COG0612	Peptidase, M16
SH06_RS11755	COG4771	TonB-dependent receptor
SH06_RS11760	COG4178	(ABC) transporter
SH06_RS11765	COG0641	radical SAM
SH06_RS11770	COG3119	arylsulfatase activity
SH06_RS11775	COG2207	Transcriptional regulator
SH06_RS11785	COG0243	molybdopterin cofactor binding
SH06_RS11790	COG3539	Fimbrial protein
SH06_RS11795	COG3539	Fimbrial protein
SH06_RS11800	COG3539	Fimbrial protein
SH06_RS11805	COG3188	usher protein
SH06_RS11810	COG4977	sequence-specific DNA binding
SH06_RS11815	COG3550	peptidyl-serine autophosphorylation
SH06_RS11820	COG1396	sequence-specific DNA binding
SH06_RS11830	COG2911	Protein conserved in bacteria
SH06_RS11830	COG3210	domain, Protein
SH06_RS11880	COG3781	membrane
SH06_RS11895	COG2199	diguanylate cyclase activity
SH06_RS11905	COG2066	Belongs to the glutaminase family
SH06_RS11910	COG1012	belongs to the aldehyde dehydrogenase family
SH06_RS11915	COG0583	DNA-binding transcription factor activity
SH06_RS11935	COG1846	Transcriptional regulator
SH06_RS11940	COG4977	sequence-specific DNA binding
SH06_RS11950	COG0697	spore germination
SH06_RS11955	COG2814	Major facilitator Superfamily
SH06_RS11965	COG3706	GGDEF domain
SH06_RS11970	COG3111	PFAM Bacterial OB fold (BOF) protein
SH06_RS11975	COG1546	Belongs to the CinA family
SH06_RS11980	COG0339	signal peptide processing
SH06_RS11985	COG4221	oxidoreductase activity
SH06_RS11990	COG1802	Transcriptional regulator
SH06_RS12000	COG0246	Mannitol dehydrogenase
SH06_RS12005	COG0477	Major facilitator Superfamily
SH06_RS12015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SH06_RS12020	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SH06_RS12025	COG5301	cellulose 1,4-beta-cellobiosidase activity
SH06_RS12030	COG4220	transposase activity
SH06_RS12040	COG5562	phage envelope protein
SH06_RS12055	COG1278	Cold shock
SH06_RS12065	COG3772	lysozyme
SH06_RS12080	COG1278	Cold shock
SH06_RS12085	COG1278	Cold shock
SH06_RS12090	COG0484	heat shock protein binding
SH06_RS12095	COG1403	HNH endonuclease
SH06_RS12115	COG2026	Addiction module toxin, RelE StbE family
SH06_RS12120	COG3077	Addiction module antitoxin, RelB DinJ family
SH06_RS12140	COG1396	sequence-specific DNA binding
SH06_RS12180	COG0582	viral genome integration into host DNA
SH06_RS12185	COG1063	alcohol dehydrogenase
SH06_RS12190	COG4948	Mandelate Racemase Muconate Lactonizing
SH06_RS12205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SH06_RS12220	COG0243	molybdopterin cofactor binding
SH06_RS12225	COG0243	molybdopterin cofactor binding
SH06_RS12230	COG0437	4 iron, 4 sulfur cluster binding
SH06_RS12235	COG3302	dmso reductase anchor subunit
SH06_RS12240	COG3381	protein complex oligomerization
SH06_RS12250	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SH06_RS12255	COG1940	carbohydrate kinase activity
SH06_RS12260	COG0583	DNA-binding transcription factor activity
SH06_RS12265	COG2814	Major facilitator Superfamily
SH06_RS12280	COG3591	Belongs to the peptidase S1B family
SH06_RS12295	COG0628	permease
SH06_RS12300	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SH06_RS12305	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SH06_RS12315	COG0531	amino acid
SH06_RS12325	COG3136	membrane protein required for alginate biosynthesis
SH06_RS12330	COG0745	RESPONSE REGULATOR receiver
SH06_RS12335	COG2205	protein histidine kinase activity
SH06_RS12345	COG0114	fumarate hydratase activity
SH06_RS12350	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SH06_RS12350	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SH06_RS12355	COG1482	cell wall glycoprotein biosynthetic process
SH06_RS12360	COG5339	Protein conserved in bacteria
SH06_RS12370	COG2211	Major facilitator Superfamily
SH06_RS12375	COG3250	beta-galactosidase activity
SH06_RS12380	COG1309	transcriptional regulator
SH06_RS12385	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS12390	COG1609	Transcriptional regulator
SH06_RS12395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS12395	COG1263	PTS System
SH06_RS12400	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SH06_RS12410	COG0673	inositol 2-dehydrogenase activity
SH06_RS12450	COG4659	FMN binding
SH06_RS12460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SH06_RS12470	COG3104	oligopeptide transport
SH06_RS12475	COG0625	glutathione transferase activity
SH06_RS12480	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
SH06_RS12495	COG3895	Periplasmic Protein
SH06_RS12505	COG3133	Outer membrane lipoprotein
SH06_RS12520	COG1566	PFAM secretion protein HlyD family protein
SH06_RS12525	COG1289	transmembrane transporter activity
SH06_RS12530	COG2032	superoxide dismutase activity
SH06_RS12535	COG4989	oxidoreductase activity
SH06_RS12540	COG3313	Fe-S protein
SH06_RS12545	COG1309	transcriptional regulator
SH06_RS12550	COG1902	pentaerythritol trinitrate reductase activity
SH06_RS12555	COG0346	lactoylglutathione lyase activity
SH06_RS12560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SH06_RS12565	COG1201	RNA secondary structure unwinding
SH06_RS12570	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SH06_RS12575	COG0791	NLP P60 protein
SH06_RS12580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SH06_RS12585	COG2814	Major facilitator Superfamily
SH06_RS12600	COG0583	DNA-binding transcription factor activity
SH06_RS12605	COG2814	Major facilitator Superfamily
SH06_RS12610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SH06_RS12615	COG0307	riboflavin synthase, alpha
SH06_RS12625	COG3468	outer membrane autotransporter barrel domain protein
SH06_RS12645	COG4529	Protein conserved in bacteria
SH06_RS12655	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
SH06_RS12660	COG0437	4 iron, 4 sulfur cluster binding
SH06_RS12670	COG2414	aldehyde ferredoxin oxidoreductase
SH06_RS12675	COG0437	4 iron, 4 sulfur cluster binding
SH06_RS12685	COG0469	pyruvate kinase activity
SH06_RS12690	COG4238	major outer membrane lipoprotein
SH06_RS12695	COG1376	ErfK ybiS ycfS ynhG family protein
SH06_RS12710	COG0719	Fe-S assembly protein
SH06_RS12715	COG0396	ATPase activity
SH06_RS12720	COG0719	Fe-S assembly protein
SH06_RS12725	COG0316	Belongs to the HesB IscA family
SH06_RS12735	COG2050	protein possibly involved in aromatic compounds catabolism
SH06_RS12740	COG0247	lactate metabolic process
SH06_RS12740	COG0277	FAD linked oxidase domain protein
SH06_RS12745	COG0628	permease
SH06_RS12755	COG0738	Major facilitator superfamily
SH06_RS12760	COG2271	Major facilitator Superfamily
SH06_RS12775	COG4670	ketone body catabolic process
SH06_RS12780	COG1960	acyl-CoA dehydrogenase activity
SH06_RS12785	COG2207	Transcriptional regulator
SH06_RS12785	COG1917	Cupin 2, conserved barrel domain protein
SH06_RS12795	COG2086	electron transfer activity
SH06_RS12800	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SH06_RS12805	COG0644	oxidoreductase
SH06_RS12810	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SH06_RS12815	COG0318	PFAM AMP-dependent synthetase and ligase
SH06_RS12820	COG0574	Belongs to the PEP-utilizing enzyme family
SH06_RS12820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SH06_RS12835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SH06_RS12840	COG4256	Hemin uptake protein
SH06_RS12850	COG2200	EAL domain
SH06_RS12855	COG0791	NLP P60 protein
SH06_RS12865	COG0386	Belongs to the glutathione peroxidase family
SH06_RS12880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SH06_RS12880	COG0072	phenylalanine-tRNA ligase activity
SH06_RS12925	COG3137	Salt-induced outer membrane protein
SH06_RS12930	COG1105	Belongs to the carbohydrate kinase PfkB family
SH06_RS12940	COG3001	Fructosamine kinase
SH06_RS12950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SH06_RS12955	COG1988	membrane-bound metal-dependent
SH06_RS12960	COG1823	symporter activity
SH06_RS12975	COG0753	catalase activity
SH06_RS12985	COG1486	melibiose metabolic process
SH06_RS12990	COG2169	Transcriptional regulator
SH06_RS12990	COG1917	Cupin 2, conserved barrel domain protein
SH06_RS12995	COG1447	Phosphotransferase system cellobiose-specific component IIA
SH06_RS13000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SH06_RS13005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SH06_RS13010	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SH06_RS13025	COG0322	excinuclease ABC activity
SH06_RS13035	COG3678	ATP-independent chaperone mediated protein folding
SH06_RS13065	COG0708	Exodeoxyribonuclease III
SH06_RS13070	COG0398	Pfam SNARE associated Golgi protein
SH06_RS13080	COG0398	Pfam SNARE associated Golgi protein
SH06_RS13085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SH06_RS13090	COG4134	Bacterial extracellular solute-binding protein
SH06_RS13095	COG4135	transport system, permease component
SH06_RS13100	COG4136	ATPase activity
SH06_RS13105	COG2897	thiosulfate sulfurtransferase activity
SH06_RS13110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SH06_RS13115	COG0494	nUDIX hydrolase
SH06_RS13125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SH06_RS13135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SH06_RS13150	COG0778	Nitroreductase
SH06_RS13160	COG0616	signal peptide processing
SH06_RS13165	COG0252	asparaginase activity
SH06_RS13170	COG1335	isochorismatase
SH06_RS13175	COG2814	Major facilitator Superfamily
SH06_RS13180	COG1349	DNA-binding transcription factor activity
SH06_RS13185	COG0667	Aldo Keto reductase
SH06_RS13190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SH06_RS13195	COG0191	fructose-bisphosphate aldolase activity
SH06_RS13200	COG1063	alcohol dehydrogenase
SH06_RS13205	COG2271	Major facilitator Superfamily
SH06_RS13210	COG1063	alcohol dehydrogenase
SH06_RS13215	COG3139	Protein of unknown function (DUF1315)
SH06_RS13225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SH06_RS13230	COG0676	glucose-6-phosphate 1-epimerase activity
SH06_RS13235	COG0656	L-ascorbic acid biosynthetic process
SH06_RS13240	COG3713	MltA-interacting MipA family protein
SH06_RS13245	COG2766	serine protein kinase
SH06_RS13255	COG2199	diguanylate cyclase activity
SH06_RS13260	COG2199	diguanylate cyclase activity
SH06_RS13265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SH06_RS13280	COG2207	Transcriptional regulator
SH06_RS13285	COG2807	transmembrane transport
SH06_RS13290	COG3189	MarR family transcriptional regulator
SH06_RS13295	COG3042	response to heat
SH06_RS13300	COG2199	diguanylate cyclase activity
SH06_RS13300	COG2203	Gaf domain
SH06_RS13310	COG2261	transglycosylase associated protein
SH06_RS13320	COG3615	Tellurite resistance protein tehB
SH06_RS13330	COG0583	DNA-binding transcription factor activity
SH06_RS13335	COG0473	3-isopropylmalate dehydrogenase activity
SH06_RS13340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SH06_RS13345	COG4638	Rieske (2fe-2S)
SH06_RS13350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SH06_RS13355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SH06_RS13360	COG0318	PFAM AMP-dependent synthetase and ligase
SH06_RS13365	COG3065	identical protein binding
SH06_RS13370	COG1214	PFAM Peptidase M22, glycoprotease
SH06_RS13375	COG1199	ATP-dependent helicase activity
SH06_RS13380	COG0251	oxidation-reduction process
SH06_RS13395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SH06_RS13405	COG1760	l-serine dehydratase
SH06_RS13410	COG2200	EAL domain
SH06_RS13415	COG1253	flavin adenine dinucleotide binding
SH06_RS13425	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS13425	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS13430	COG3715	PTS system
SH06_RS13435	COG3716	PTS system mannose fructose sorbose family IID component
SH06_RS13455	COG2226	methyltransferase
SH06_RS13490	COG1414	Transcriptional regulator
SH06_RS13495	COG2814	Major facilitator Superfamily
SH06_RS13505	COG0793	Belongs to the peptidase S41A family
SH06_RS13515	COG1956	GAF domain-containing protein
SH06_RS13520	COG2995	paraquat-inducible protein a
SH06_RS13525	COG3008	intermembrane lipid transfer
SH06_RS13545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SH06_RS13560	COG1276	copper resistance
SH06_RS13565	COG2372	response to copper ion
SH06_RS13575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SH06_RS13580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SH06_RS13585	COG1770	oligopeptidase
SH06_RS13590	COG2979	Protein of unknown function (DUF533)
SH06_RS13605	COG3141	response to X-ray
SH06_RS13615	COG0800	Aldolase
SH06_RS13620	COG0129	dihydroxy-acid dehydratase activity
SH06_RS13625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SH06_RS13635	COG1737	Transcriptional regulator
SH06_RS13640	COG0469	pyruvate kinase activity
SH06_RS13645	COG1560	Kdo2-lipid A biosynthetic process
SH06_RS13650	COG0739	heme binding
SH06_RS13655	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
SH06_RS13665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SH06_RS13690	COG0217	transcriptional regulatory protein
SH06_RS13695	COG0494	nUDIX hydrolase
SH06_RS13705	COG1335	isochorismatase
SH06_RS13710	COG1801	Protein of unknown function DUF72
SH06_RS13715	COG3788	relative of glutathione S-transferase, MAPEG superfamily
SH06_RS13730	COG0243	molybdopterin cofactor binding
SH06_RS13735	COG3005	denitrification pathway
SH06_RS13745	COG3102	Protein conserved in bacteria
SH06_RS13755	COG3755	Protein conserved in bacteria
SH06_RS13765	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SH06_RS13770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SH06_RS13775	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
SH06_RS13780	COG0745	RESPONSE REGULATOR receiver
SH06_RS13785	COG2201	protein-glutamate methylesterase activity
SH06_RS13790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SH06_RS13795	COG0840	transmembrane signaling receptor activity
SH06_RS13800	COG0840	transmembrane signaling receptor activity
SH06_RS13805	COG0835	chemotaxis
SH06_RS13810	COG0643	Histidine kinase
SH06_RS13810	COG2198	Histidine kinase
SH06_RS13815	COG1360	Flagellar Motor Protein
SH06_RS13820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SH06_RS13835	COG0589	response to stress
SH06_RS13845	COG1877	trehalose-phosphatase activity
SH06_RS13850	COG1172	Belongs to the binding-protein-dependent transport system permease family
SH06_RS13855	COG1129	ABC transporter
SH06_RS13860	COG1879	ABC-type sugar transport system periplasmic component
SH06_RS13865	COG1528	Iron-storage protein
SH06_RS13885	COG1528	Iron-storage protein
SH06_RS13895	COG0814	amino acid
SH06_RS13900	COG3012	SEC-C Motif Domain Protein
SH06_RS13900	COG3318	Belongs to the UPF0149 family
SH06_RS13930	COG2197	response regulator
SH06_RS13945	COG2197	response regulator
SH06_RS13950	COG1126	abc transporter atp-binding protein
SH06_RS13955	COG0765	amino acid transport
SH06_RS13965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SH06_RS13975	COG1191	sigma factor activity
SH06_RS13980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SH06_RS13985	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SH06_RS13990	COG1516	flagellar protein fliS
SH06_RS14000	COG0366	Alpha amylase catalytic
SH06_RS14010	COG2391	methyltransferase activity
SH06_RS14015	COG0425	Belongs to the sulfur carrier protein TusA family
SH06_RS14020	COG2135	peptidase activity
SH06_RS14025	COG0454	-acetyltransferase
SH06_RS14050	COG1766	The M ring may be actively involved in energy transduction
SH06_RS14055	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SH06_RS14060	COG1317	bacterial-type flagellum organization
SH06_RS14065	COG1157	protein secretion by the type III secretion system
SH06_RS14070	COG2882	bacterial-type flagellum organization
SH06_RS14075	COG3144	bacterial-type flagellum assembly
SH06_RS14080	COG1580	Controls the rotational direction of flagella during chemotaxis
SH06_RS14085	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SH06_RS14090	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SH06_RS14095	COG3190	flagellar
SH06_RS14100	COG1338	Plays a role in the flagellum-specific transport system
SH06_RS14105	COG1987	bacterial-type flagellum assembly
SH06_RS14110	COG1684	flagellar biosynthetic protein fliR
SH06_RS14115	COG2197	response regulator
SH06_RS14135	COG3706	GGDEF domain
SH06_RS14140	COG5475	Uncharacterized small protein (DUF2158)
SH06_RS14145	COG2354	Protein conserved in bacteria
SH06_RS14150	COG0697	spore germination
SH06_RS14155	COG3727	T/G mismatch-specific endonuclease activity
SH06_RS14160	COG0270	DNA (cytosine-5-)-methyltransferase activity
SH06_RS14165	COG1418	mRNA catabolic process
SH06_RS14195	COG2205	protein histidine kinase activity
SH06_RS14200	COG0745	RESPONSE REGULATOR receiver
SH06_RS14205	COG2351	hydroxyisourate hydrolase activity
SH06_RS14220	COG3443	Belongs to the bacterial solute-binding protein 9 family
SH06_RS14225	COG3038	cytochrome b561
SH06_RS14250	COG1470	cell adhesion involved in biofilm formation
SH06_RS14250	COG1388	LysM domain
SH06_RS14260	COG0477	Major facilitator Superfamily
SH06_RS14265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SH06_RS14270	COG0217	transcriptional regulatory protein
SH06_RS14280	COG0534	Mate efflux family protein
SH06_RS14290	COG0583	DNA-binding transcription factor activity
SH06_RS14295	COG0583	DNA-binding transcription factor activity
SH06_RS14305	COG1376	ErfK ybiS ycfS ynhG family protein
SH06_RS14320	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
SH06_RS14330	COG3039	Transposase
SH06_RS14350	COG4771	TonB-dependent receptor
SH06_RS14360	COG3468	outer membrane autotransporter barrel domain protein
SH06_RS14370	COG2003	Belongs to the UPF0758 family
SH06_RS14410	COG1289	transmembrane transporter activity
SH06_RS14420	COG1686	Belongs to the peptidase S11 family
SH06_RS14425	COG2925	Exonuclease
SH06_RS14430	COG0425	Belongs to the sulfur carrier protein TusA family
SH06_RS14435	COG2391	methyltransferase activity
SH06_RS14440	COG0531	amino acid
SH06_RS14445	COG0583	DNA-binding transcription factor activity
SH06_RS14450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SH06_RS14455	COG4115	mRNA cleavage
SH06_RS14460	COG2161	toxin-antitoxin pair type II binding
SH06_RS14470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SH06_RS14480	COG0131	Imidazoleglycerol-phosphate dehydratase
SH06_RS14480	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SH06_RS14485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SH06_RS14500	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SH06_RS14500	COG0140	phosphoribosyl-ATP diphosphatase activity
SH06_RS14505	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
SH06_RS14510	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SH06_RS14515	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SH06_RS14530	COG0438	transferase activity, transferring glycosyl groups
SH06_RS14535	COG0110	maltose O-acetyltransferase activity
SH06_RS14540	COG0438	transferase activity, transferring glycosyl groups
SH06_RS14550	COG0562	UDP-galactopyranose mutase
SH06_RS14555	COG2244	polysaccharide biosynthetic process
SH06_RS14560	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SH06_RS14565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SH06_RS14575	COG1088	dTDP-glucose 4,6-dehydratase activity
SH06_RS14580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SH06_RS14590	COG0438	transferase activity, transferring glycosyl groups
SH06_RS14595	COG2327	Polysaccharide pyruvyl transferase
SH06_RS14600	COG2244	polysaccharide biosynthetic process
SH06_RS14605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SH06_RS14610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SH06_RS14615	COG0662	Cupin 2, conserved barrel domain protein
SH06_RS14615	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SH06_RS14620	COG0297	glycogen (starch) synthase activity
SH06_RS14625	COG1051	belongs to the nudix hydrolase family
SH06_RS14630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SH06_RS14635	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SH06_RS14640	COG0110	maltose O-acetyltransferase activity
SH06_RS14645	COG1216	Glycosyl transferase, family 2
SH06_RS14655	COG0438	transferase activity, transferring glycosyl groups
SH06_RS14660	COG1045	serine acetyltransferase
SH06_RS14665	COG0463	Glycosyl transferase, family 2
SH06_RS14670	COG0489	protein tyrosine kinase activity
SH06_RS14670	COG3206	protein involved in exopolysaccharide biosynthesis
SH06_RS14675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SH06_RS14680	COG1596	polysaccharide export
SH06_RS14685	COG1253	flavin adenine dinucleotide binding
SH06_RS14690	COG2982	Protein involved in outer membrane biogenesis
SH06_RS14700	COG0572	uridine kinase
SH06_RS14705	COG3447	MASE1 domain protein
SH06_RS14705	COG5002	protein histidine kinase activity
SH06_RS14705	COG5001	Diguanylate cyclase
SH06_RS14710	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
SH06_RS14720	COG0443	Heat shock 70 kDa protein
SH06_RS14725	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
SH06_RS14730	COG3779	Protein conserved in bacteria
SH06_RS14735	COG0631	protein serine/threonine phosphatase activity
SH06_RS14740	COG4245	von Willebrand factor, type A
SH06_RS14765	COG2205	protein histidine kinase activity
SH06_RS14770	COG0745	RESPONSE REGULATOR receiver
SH06_RS14775	COG3422	double-strand break repair
SH06_RS14780	COG0826	peptidase U32
SH06_RS14815	COG2801	Transposase and inactivated derivatives
SH06_RS14825	COG1063	alcohol dehydrogenase
SH06_RS14830	COG3775	system Galactitol-specific IIC component
SH06_RS14835	COG3414	Phosphotransferase system galactitol-specific IIB component
SH06_RS14840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS14855	COG1830	Aldolase
SH06_RS14860	COG2211	Major facilitator Superfamily
SH06_RS14865	COG1397	ADP-ribosylglycohydrolase
SH06_RS14870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SH06_RS14875	COG2188	Transcriptional regulator
SH06_RS14880	COG3757	hydrolase, family 25
SH06_RS14885	COG0351	phosphomethylpyrimidine kinase
SH06_RS14900	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
SH06_RS14905	COG5455	response to cobalt ion
SH06_RS14910	COG3539	Fimbrial protein
SH06_RS14915	COG3188	usher protein
SH06_RS14920	COG3121	Chaperone
SH06_RS14925	COG3539	Fimbrial protein
SH06_RS14940	COG0489	protein tyrosine kinase activity
SH06_RS14960	COG3831	ATPase activity
SH06_RS14970	COG0714	Associated with various cellular activities
SH06_RS14975	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SH06_RS14980	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SH06_RS14985	COG4715	Zinc finger, swim domain protein
SH06_RS14990	COG4808	Protein conserved in bacteria
SH06_RS14995	COG4807	Protein conserved in bacteria
SH06_RS15000	COG3279	Response regulator of the LytR AlgR family
SH06_RS15005	COG3275	phosphorelay sensor kinase activity
SH06_RS15010	COG0789	Transcriptional regulator
SH06_RS15020	COG1174	glycine betaine transport
SH06_RS15025	COG1125	glycine betaine transport
SH06_RS15030	COG1174	glycine betaine transport
SH06_RS15035	COG1732	Glycine betaine
SH06_RS15040	COG1472	Belongs to the glycosyl hydrolase 3 family
SH06_RS15045	COG0277	FAD linked oxidase domain protein
SH06_RS15050	COG1686	Belongs to the peptidase S11 family
SH06_RS15060	COG0586	Pfam SNARE associated Golgi protein
SH06_RS15065	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS15080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SH06_RS15090	COG1346	cytolysis
SH06_RS15100	COG2949	membrane
SH06_RS15110	COG0493	'glutamate synthase
SH06_RS15115	COG0167	dihydroorotate dehydrogenase activity
SH06_RS15115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SH06_RS15120	COG4211	Belongs to the binding-protein-dependent transport system permease family
SH06_RS15135	COG1879	ABC-type sugar transport system periplasmic component
SH06_RS15140	COG1609	Transcriptional regulator
SH06_RS15150	COG2311	Membrane
SH06_RS15170	COG4771	TonB-dependent receptor
SH06_RS15175	COG0833	amino acid
SH06_RS15180	COG0583	DNA-binding transcription factor activity
SH06_RS15185	COG2855	membrane
SH06_RS15195	COG1522	sequence-specific DNA binding
SH06_RS15195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SH06_RS15200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SH06_RS15210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SH06_RS15215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SH06_RS15220	COG2313	pseudouridylate synthase activity
SH06_RS15225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SH06_RS15230	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SH06_RS15230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS15230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS15235	COG1105	Belongs to the carbohydrate kinase PfkB family
SH06_RS15240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS15240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS15245	COG2814	Major facilitator Superfamily
SH06_RS15260	COG0246	Mannitol dehydrogenase
SH06_RS15265	COG0523	cobalamin synthesis protein
SH06_RS15270	COG0671	phosphoesterase, PA-phosphatase related
SH06_RS15275	COG0791	NLP P60 protein
SH06_RS15280	COG2200	EAL domain
SH06_RS15285	COG4166	transmembrane transport
SH06_RS15290	COG4174	ABC transporter (Permease)
SH06_RS15295	COG4239	(ABC) transporter, permease
SH06_RS15300	COG4172	Belongs to the ABC transporter superfamily
SH06_RS15310	COG2814	Major facilitator Superfamily
SH06_RS15315	COG1187	pseudouridine synthase activity
SH06_RS15320	COG1061	Type III restriction enzyme res subunit
SH06_RS15340	COG3083	sulfuric ester hydrolase activity
SH06_RS15350	COG3468	outer membrane autotransporter barrel domain protein
SH06_RS15365	COG2197	response regulator
SH06_RS15370	COG4235	cytochrome complex assembly
SH06_RS15370	COG3088	subunit of a heme lyase
SH06_RS15375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SH06_RS15380	COG1138	Cytochrome C-type biogenesis protein
SH06_RS15390	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SH06_RS15395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SH06_RS15400	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SH06_RS15405	COG4133	protoheme IX ABC transporter activity
SH06_RS15410	COG3005	denitrification pathway
SH06_RS15415	COG3043	anaerobic respiration
SH06_RS15420	COG0348	domain, Protein
SH06_RS15425	COG0437	4 iron, 4 sulfur cluster binding
SH06_RS15435	COG3062	negative regulation of establishment of protein localization
SH06_RS15440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS15440	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS15460	COG4615	Cyclic peptide transporter
SH06_RS15465	COG3145	DNA-N1-methyladenine dioxygenase activity
SH06_RS15470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SH06_RS15470	COG2169	Transcriptional regulator
SH06_RS15475	COG1477	protein flavinylation
SH06_RS15480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SH06_RS15495	COG0642	Histidine kinase
SH06_RS15495	COG2198	Histidine kinase
SH06_RS15500	COG2197	response regulator
SH06_RS15505	COG2205	protein histidine kinase activity
SH06_RS15505	COG0784	Response regulator, receiver
SH06_RS15510	COG3852	Histidine kinase
SH06_RS15515	COG2204	response regulator
SH06_RS15520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SH06_RS15525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SH06_RS15530	COG2031	fatty acid transporter
SH06_RS15535	COG0183	Belongs to the thiolase family
SH06_RS15540	COG4676	Protein conserved in bacteria
SH06_RS15545	COG5445	Predicted secreted protein (DUF2300)
SH06_RS15550	COG2373	Large extracellular alpha-helical protein
SH06_RS15560	COG3234	Protein of unknown function (DUF1175)
SH06_RS15565	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
SH06_RS15570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SH06_RS15580	COG3468	outer membrane autotransporter barrel domain protein
SH06_RS15590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SH06_RS15595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SH06_RS15600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SH06_RS15605	COG3642	lipopolysaccharide core region biosynthetic process
SH06_RS15610	COG0583	DNA-binding transcription factor activity
SH06_RS15615	COG0584	glycerophosphoryl diester phosphodiesterase
SH06_RS15620	COG2271	Major facilitator Superfamily
SH06_RS15625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SH06_RS15635	COG0247	lactate metabolic process
SH06_RS15640	COG5464	transposase or invertase
SH06_RS15655	COG2271	Major facilitator Superfamily
SH06_RS15665	COG1414	Transcriptional regulator
SH06_RS15730	COG0318	PFAM AMP-dependent synthetase and ligase
SH06_RS15740	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SH06_RS15755	COG1169	isochorismate synthase
SH06_RS15760	COG4575	ribosome binding
SH06_RS15765	COG2153	protein acetylation
SH06_RS15775	COG5160	protein modification by small protein removal
SH06_RS15780	COG2304	oxidoreductase activity
SH06_RS15785	COG2234	aminopeptidase activity
SH06_RS15805	COG0457	Tetratricopeptide repeat
SH06_RS15815	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SH06_RS15820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SH06_RS15830	COG0839	Belongs to the complex I subunit 6 family
SH06_RS15845	COG1034	ATP synthesis coupled electron transport
SH06_RS15850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SH06_RS15855	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
SH06_RS15875	COG0583	DNA-binding transcription factor activity
SH06_RS15880	COG0436	Aminotransferase
SH06_RS15890	COG0490	domain, Protein
SH06_RS15890	COG0471	metal ion transport
SH06_RS15895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SH06_RS15915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SH06_RS15920	COG0857	belongs to the CobB CobQ family
SH06_RS15920	COG0280	phosphate acetyltransferase
SH06_RS15925	COG1288	antiporter activity
SH06_RS15930	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SH06_RS15935	COG0622	Phosphoesterase
SH06_RS15940	COG0625	glutathione transferase activity
SH06_RS15945	COG0625	glutathione transferase activity
SH06_RS15950	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SH06_RS15955	COG1090	epimerase
SH06_RS15960	COG5464	transposase or invertase
SH06_RS15965	COG4598	ABC transporter
SH06_RS15970	COG4160	amino acid transport
SH06_RS15975	COG4215	(ABC) transporter
SH06_RS15980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SH06_RS15985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SH06_RS15990	COG0163	prenyltransferase activity
SH06_RS15995	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SH06_RS16000	COG1286	toxin biosynthetic process
SH06_RS16005	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
SH06_RS16010	COG0285	dihydrofolate synthase activity
SH06_RS16020	COG0586	Pfam SNARE associated Golgi protein
SH06_RS16030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SH06_RS16045	COG2814	Major facilitator Superfamily
SH06_RS16050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SH06_RS16065	COG3101	peptidyl-lysine hydroxylation
SH06_RS16070	COG0730	response to heat
SH06_RS16085	COG2890	protein-(glutamine-N5) methyltransferase activity
SH06_RS16100	COG3539	Fimbrial protein
SH06_RS16105	COG3539	Fimbrial protein
SH06_RS16110	COG3539	Fimbrial protein
SH06_RS16115	COG3121	Chaperone
SH06_RS16125	COG3539	Fimbrial protein
SH06_RS16130	COG2062	phosphohistidine phosphatase, SixA
SH06_RS16145	COG3691	Protein conserved in bacteria
SH06_RS16150	COG2067	long-chain fatty acid transport protein
SH06_RS16160	COG2853	Lipoprotein
SH06_RS16165	COG2116	formate transmembrane transporter activity
SH06_RS16175	COG0582	viral genome integration into host DNA
SH06_RS16180	COG2246	polysaccharide biosynthetic process
SH06_RS16185	COG0463	Glycosyl transferase, family 2
SH06_RS16210	COG4725	Belongs to the MT-A70-like family
SH06_RS16235	COG5532	Uncharacterized conserved protein (DUF2303)
SH06_RS16240	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
SH06_RS16260	COG0583	DNA-binding transcription factor activity
SH06_RS16265	COG2610	gluconate transmembrane transporter activity
SH06_RS16275	COG0477	Major facilitator Superfamily
SH06_RS16280	COG1566	PFAM secretion protein HlyD family protein
SH06_RS16285	COG2197	response regulator
SH06_RS16290	COG2205	protein histidine kinase activity
SH06_RS16290	COG2198	Histidine kinase
SH06_RS16290	COG0784	Response regulator, receiver
SH06_RS16290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SH06_RS16295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SH06_RS16300	COG0679	Auxin Efflux Carrier
SH06_RS16305	COG0028	Belongs to the TPP enzyme family
SH06_RS16335	COG1560	Kdo2-lipid A biosynthetic process
SH06_RS16340	COG0436	Aminotransferase
SH06_RS16345	COG3275	phosphorelay sensor kinase activity
SH06_RS16350	COG3279	Response regulator of the LytR AlgR family
SH06_RS16355	COG2207	Transcriptional regulator
SH06_RS16360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SH06_RS16360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS16360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS16365	COG1363	Peptidase, m42
SH06_RS16370	COG0006	proline dipeptidase activity
SH06_RS16375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS16380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SH06_RS16410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SH06_RS16415	COG3385	transposase activity
SH06_RS16420	COG2200	EAL domain
SH06_RS16420	COG2199	diguanylate cyclase activity
SH06_RS16435	COG3415	Transposase
SH06_RS16440	COG3415	Transposase
SH06_RS16470	COG0583	DNA-binding transcription factor activity
SH06_RS16480	COG2211	Major facilitator Superfamily
SH06_RS16485	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SH06_RS16495	COG0583	DNA-binding transcription factor activity
SH06_RS16500	COG0385	Bile acid
SH06_RS16505	COG3530	Putative quorum-sensing-regulated virulence factor
SH06_RS16525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SH06_RS16530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS16535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SH06_RS16540	COG2190	(PTS) system
SH06_RS16555	COG4884	unkown
SH06_RS16555	COG3831	ATPase activity
SH06_RS16560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SH06_RS16565	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SH06_RS16570	COG4208	sulfate ABC transporter
SH06_RS16575	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SH06_RS16580	COG4150	thiosulfate binding
SH06_RS16585	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS16600	COG1263	PTS System
SH06_RS16600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS16605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SH06_RS16610	COG2837	iron assimilation
SH06_RS16625	COG0456	acetyltransferase
SH06_RS16630	COG0860	N-Acetylmuramoyl-L-alanine amidase
SH06_RS16640	COG2207	Transcriptional regulator
SH06_RS16645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SH06_RS16650	COG4816	utilization protein
SH06_RS16660	COG4303	Ethanolamine ammonia lyase large subunit
SH06_RS16665	COG4819	ethanolamine utilization protein
SH06_RS16670	COG3192	ethanolamine utilization protein
SH06_RS16675	COG1454	alcohol dehydrogenase
SH06_RS16680	COG4820	ethanolamine utilization protein (EutJ)
SH06_RS16685	COG1012	belongs to the aldehyde dehydrogenase family
SH06_RS16690	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SH06_RS16695	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SH06_RS16700	COG0280	phosphate acetyltransferase
SH06_RS16705	COG4812	Cobalamin adenosyltransferase
SH06_RS16710	COG4766	ethanolamine catabolic process
SH06_RS16715	COG4917	ethanolamine utilization protein
SH06_RS16720	COG4810	utilization protein
SH06_RS16725	COG0281	malic enzyme
SH06_RS16725	COG0280	phosphate acetyltransferase
SH06_RS16730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SH06_RS16735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SH06_RS16740	COG5342	invasion associated locus B
SH06_RS16750	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS16750	COG0493	'glutamate synthase
SH06_RS16755	COG3850	Histidine kinase
SH06_RS16760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SH06_RS16770	COG1393	Belongs to the ArsC family
SH06_RS16785	COG0400	carboxylic ester hydrolase activity
SH06_RS16790	COG1444	tRNA N-acetyltransferase activity
SH06_RS16795	COG2321	neutral zinc metallopeptidase
SH06_RS16810	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
SH06_RS16820	COG2716	regulation of RNA biosynthetic process
SH06_RS16825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SH06_RS16830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS16835	COG0651	ATP synthesis coupled electron transport
SH06_RS16840	COG0650	Formate hydrogenlyase subunit 4
SH06_RS16845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SH06_RS16850	COG4237	Hydrogenase 4 membrane
SH06_RS16855	COG0651	ATP synthesis coupled electron transport
SH06_RS16860	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
SH06_RS16860	COG3261	NADH dehydrogenase
SH06_RS16865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SH06_RS16870	COG3260	NADH ubiquinone oxidoreductase 20
SH06_RS16880	COG3604	Transcriptional regulator
SH06_RS16885	COG2116	formate transmembrane transporter activity
SH06_RS16890	COG0628	permease
SH06_RS16895	COG4783	chaperone-mediated protein folding
SH06_RS16900	COG1393	Belongs to the ArsC family
SH06_RS16910	COG2233	PERMEase
SH06_RS16925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SH06_RS16930	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SH06_RS16935	COG0248	Ppx GppA phosphatase
SH06_RS16940	COG2200	EAL domain
SH06_RS16955	COG3133	Outer membrane lipoprotein
SH06_RS16970	COG0516	GMP reductase activity
SH06_RS16970	COG0517	IMP dehydrogenase activity
SH06_RS16980	COG1645	bacterial-type flagellum-dependent swarming motility
SH06_RS16990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SH06_RS16995	COG2976	Protein conserved in bacteria
SH06_RS17025	COG4953	penicillin-binding protein 1C
SH06_RS17030	COG2373	Large extracellular alpha-helical protein
SH06_RS17035	COG2897	thiosulfate sulfurtransferase activity
SH06_RS17050	COG2975	iron-sulfur cluster assembly
SH06_RS17055	COG0633	Ferredoxin
SH06_RS17075	COG0822	iron-sulfur transferase activity
SH06_RS17095	COG0483	inositol monophosphate 1-phosphatase activity
SH06_RS17100	COG1073	alpha beta
SH06_RS17105	COG3711	transcriptional antiterminator
SH06_RS17110	COG2814	Major facilitator Superfamily
SH06_RS17115	COG0583	DNA-binding transcription factor activity
SH06_RS17120	COG4638	Rieske (2fe-2S)
SH06_RS17145	COG2259	Doxx family
SH06_RS17150	COG2017	converts alpha-aldose to the beta-anomer
SH06_RS17155	COG1063	alcohol dehydrogenase
SH06_RS17160	COG1172	Belongs to the binding-protein-dependent transport system permease family
SH06_RS17165	COG1129	ABC transporter
SH06_RS17170	COG1879	ABC-type sugar transport system periplasmic component
SH06_RS17175	COG0457	Tetratricopeptide repeat
SH06_RS17180	COG1940	carbohydrate kinase activity
SH06_RS17190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SH06_RS17190	COG1017	nitric oxide dioxygenase activity
SH06_RS17195	COG0347	Belongs to the P(II) protein family
SH06_RS17200	COG2204	response regulator
SH06_RS17205	COG3170	Tfp pilus assembly protein FimV
SH06_RS17210	COG2205	protein histidine kinase activity
SH06_RS17215	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SH06_RS17215	COG0047	phosphoribosylformylglycinamidine synthase activity
SH06_RS17230	COG0560	Phosphoserine phosphatase
SH06_RS17235	COG1737	Transcriptional regulator
SH06_RS17240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS17265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SH06_RS17285	COG0681	Belongs to the peptidase S26 family
SH06_RS17295	COG3086	response to oxidative stress
SH06_RS17300	COG3026	antisigma factor binding
SH06_RS17305	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
SH06_RS17310	COG1595	DNA-templated transcription, initiation
SH06_RS17320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SH06_RS17330	COG0513	Belongs to the DEAD box helicase family
SH06_RS17340	COG0583	DNA-binding transcription factor activity
SH06_RS17360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SH06_RS17370	COG3118	belongs to the thioredoxin family
SH06_RS17375	COG3148	PFAM DTW domain containing protein
SH06_RS17380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SH06_RS17380	COG1042	CoA-binding domain protein
SH06_RS17380	COG0045	succinate-CoA ligase (ADP-forming) activity
SH06_RS17385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SH06_RS17390	COG5544	Lipoprotein
SH06_RS17395	COG0477	Major facilitator Superfamily
SH06_RS17425	COG0542	response to heat
SH06_RS17430	COG1496	oxidoreductase activity
SH06_RS17435	COG0564	pseudouridine synthase activity
SH06_RS17440	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SH06_RS17450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SH06_RS17455	COG0077	Prephenate dehydratase
SH06_RS17455	COG1605	Chorismate mutase
SH06_RS17460	COG1605	Chorismate mutase
SH06_RS17460	COG0287	Prephenate dehydrogenase
SH06_RS17465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SH06_RS17480	COG2199	diguanylate cyclase activity
SH06_RS17485	COG2885	chlorophyll binding
SH06_RS17510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SH06_RS17515	COG4137	Cytochrome C assembly protein
SH06_RS17520	COG4536	flavin adenine dinucleotide binding
SH06_RS17540	COG0497	DNA recombination
SH06_RS17545	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SH06_RS17555	COG2867	negative regulation of translational initiation
SH06_RS17565	COG0582	viral genome integration into host DNA
SH06_RS17575	COG3311	Transcriptional regulator
SH06_RS17580	COG4983	Phage plasmid primase, P4 family domain protein
SH06_RS17590	COG1204	response to ionizing radiation
SH06_RS17600	COG1479	Protein of unknown function DUF262
SH06_RS17615	COG3596	GTP binding
SH06_RS17625	COG2378	regulation of single-species biofilm formation
SH06_RS17665	COG2003	Belongs to the UPF0758 family
SH06_RS17680	COG3468	outer membrane autotransporter barrel domain protein
SH06_RS17715	COG0366	Alpha amylase catalytic
SH06_RS17720	COG0366	Alpha amylase catalytic
SH06_RS17725	COG0366	Alpha amylase catalytic
SH06_RS17735	COG0579	oxidoreductase
SH06_RS17740	COG1012	belongs to the aldehyde dehydrogenase family
SH06_RS17745	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SH06_RS17750	COG1113	amino acid transport
SH06_RS17755	COG1802	Transcriptional regulator
SH06_RS17760	COG1652	LysM domain
SH06_RS17765	COG0401	homolog of Blt101
SH06_RS17770	COG0640	Transcriptional regulator
SH06_RS17775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SH06_RS17780	COG2916	Histone family protein nucleoid-structuring protein H-NS
SH06_RS17795	COG4575	ribosome binding
SH06_RS17800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SH06_RS17810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SH06_RS17815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SH06_RS17820	COG4175	Glycine betaine
SH06_RS17825	COG4176	ABC-type proline glycine betaine transport system permease component
SH06_RS17830	COG2113	Glycine betaine
SH06_RS17840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SH06_RS17850	COG1846	Transcriptional regulator
SH06_RS17855	COG1566	PFAM secretion protein HlyD family protein
SH06_RS17860	COG2814	Major facilitator Superfamily
SH06_RS17875	COG1238	metal cluster binding
SH06_RS17880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SH06_RS17915	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SH06_RS17950	COG1546	Belongs to the CinA family
SH06_RS17955	COG2951	lytic endotransglycosylase activity
SH06_RS17960	COG3730	PTS system glucitol sorbitol-specific
SH06_RS17965	COG3732	PTS system glucitol sorbitol-specific
SH06_RS17970	COG3731	PTS system glucitol sorbitol-specific IIA component
SH06_RS17975	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS17980	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS17985	COG1349	DNA-binding transcription factor activity
SH06_RS17990	COG0517	IMP dehydrogenase activity
SH06_RS17990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SH06_RS18010	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SH06_RS18015	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS18020	COG1609	Transcriptional regulator
SH06_RS18025	COG1263	PTS System
SH06_RS18025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS18030	COG2723	6-phospho-beta-galactosidase activity
SH06_RS18035	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SH06_RS18045	COG3260	NADH ubiquinone oxidoreductase 20
SH06_RS18050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SH06_RS18055	COG3261	NADH dehydrogenase
SH06_RS18055	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
SH06_RS18060	COG0650	Formate hydrogenlyase subunit 4
SH06_RS18065	COG0651	ATP synthesis coupled electron transport
SH06_RS18070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS18085	COG0375	protein maturation
SH06_RS18090	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SH06_RS18095	COG0298	carbon dioxide binding
SH06_RS18100	COG0409	Hydrogenase expression formation protein
SH06_RS18105	COG0309	Hydrogenase expression formation protein (HypE)
SH06_RS18110	COG3604	Transcriptional regulator
SH06_RS18125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SH06_RS18130	COG1349	DNA-binding transcription factor activity
SH06_RS18135	COG2084	Dehydrogenase
SH06_RS18140	COG3395	kinase activity
SH06_RS18145	COG0235	Class ii aldolase
SH06_RS18150	COG3622	Belongs to the hyi family
SH06_RS18155	COG2610	gluconate transmembrane transporter activity
SH06_RS18160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SH06_RS18165	COG4942	peptidase
SH06_RS18165	COG1388	LysM domain
SH06_RS18220	COG2234	aminopeptidase activity
SH06_RS18225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SH06_RS18230	COG1518	maintenance of DNA repeat elements
SH06_RS18245	COG1857	crispr-associated protein
SH06_RS18260	COG1203	CRISPR-associated helicase, Cas3
SH06_RS18275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SH06_RS18280	COG0720	synthase
SH06_RS18285	COG0644	oxidoreductase
SH06_RS18290	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SH06_RS18295	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SH06_RS18300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SH06_RS18305	COG2086	electron transfer activity
SH06_RS18310	COG0477	Major facilitator Superfamily
SH06_RS18315	COG0277	FAD linked oxidase domain protein
SH06_RS18320	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS18325	COG2223	nitrite transmembrane transporter activity
SH06_RS18330	COG1070	Carbohydrate kinase
SH06_RS18335	COG0602	queuosine metabolic process
SH06_RS18345	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
SH06_RS18360	COG3956	TIGRFAM MazG family protein
SH06_RS18365	COG2337	Toxic component of a toxin-antitoxin (TA) module
SH06_RS18370	COG2336	PFAM SpoVT AbrB
SH06_RS18375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SH06_RS18380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SH06_RS18385	COG3437	response regulator, receiver
SH06_RS18385	COG2205	protein histidine kinase activity
SH06_RS18385	COG3850	Histidine kinase
SH06_RS18385	COG4999	Histidine kinase
SH06_RS18390	COG4948	Mandelate Racemase Muconate Lactonizing
SH06_RS18395	COG4948	Mandelate Racemase Muconate Lactonizing
SH06_RS18400	COG2271	Major facilitator Superfamily
SH06_RS18405	COG0716	FMN binding
SH06_RS18410	COG0564	pseudouridine synthase activity
SH06_RS18415	COG3098	single-species biofilm formation
SH06_RS18435	COG1611	Belongs to the LOG family
SH06_RS18440	COG0814	amino acid
SH06_RS18445	COG1760	l-serine dehydratase
SH06_RS18455	COG1454	alcohol dehydrogenase
SH06_RS18460	COG0235	Class ii aldolase
SH06_RS18465	COG0738	Major facilitator superfamily
SH06_RS18475	COG1070	Carbohydrate kinase
SH06_RS18485	COG1349	DNA-binding transcription factor activity
SH06_RS18495	COG2363	Small membrane protein
SH06_RS18500	COG0583	DNA-binding transcription factor activity
SH06_RS18510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SH06_RS18515	COG2166	iron-sulfur cluster assembly
SH06_RS18520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SH06_RS18525	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
SH06_RS18545	COG0860	N-Acetylmuramoyl-L-alanine amidase
SH06_RS18550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SH06_RS18550	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SH06_RS18560	COG1074	ATP-dependent DNA helicase activity
SH06_RS18565	COG1025	Belongs to the peptidase M16 family
SH06_RS18570	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SH06_RS18575	COG4967	type IV pilus modification protein PilV
SH06_RS18585	COG4795	General secretion pathway protein
SH06_RS18590	COG2165	general secretion pathway protein
SH06_RS18605	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
SH06_RS18630	COG0861	Integral membrane protein TerC family
SH06_RS18640	COG0667	Aldo Keto reductase
SH06_RS18655	COG1609	Transcriptional regulator
SH06_RS18665	COG0583	DNA-binding transcription factor activity
SH06_RS18670	COG1794	racemase activity, acting on amino acids and derivatives
SH06_RS18675	COG2814	Major facilitator Superfamily
SH06_RS18680	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS18690	COG0183	Belongs to the thiolase family
SH06_RS18695	COG0814	amino acid
SH06_RS18700	COG2771	luxR family
SH06_RS18705	COG3710	Transcriptional regulator
SH06_RS18725	COG0457	Tetratricopeptide repeat
SH06_RS18730	COG3710	Transcriptional regulator
SH06_RS18730	COG0457	Tetratricopeptide repeat
SH06_RS18745	COG2197	response regulator
SH06_RS18750	COG2197	response regulator
SH06_RS18780	COG3387	PFAM Glycoside hydrolase 15-related
SH06_RS18785	COG3387	PFAM Glycoside hydrolase 15-related
SH06_RS18795	COG4942	peptidase
SH06_RS18800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SH06_RS18805	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SH06_RS18810	COG2080	2 iron, 2 sulfur cluster binding
SH06_RS18815	COG3829	transcription factor binding
SH06_RS18820	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SH06_RS18825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SH06_RS18830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SH06_RS18840	COG0549	Belongs to the carbamate kinase family
SH06_RS18845	COG3608	succinylglutamate desuccinylase aspartoacylase
SH06_RS18845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SH06_RS18850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SH06_RS18855	COG2068	MobA-Related Protein
SH06_RS18860	COG0493	'glutamate synthase
SH06_RS18860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS18865	COG0402	S-adenosylhomocysteine deaminase activity
SH06_RS18870	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SH06_RS18875	COG2080	2 iron, 2 sulfur cluster binding
SH06_RS18875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SH06_RS18880	COG2233	PERMEase
SH06_RS18885	COG0402	S-adenosylhomocysteine deaminase activity
SH06_RS18890	COG2252	PERMEase
SH06_RS18895	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS18900	COG0493	'glutamate synthase
SH06_RS18900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS18910	COG2233	PERMEase
SH06_RS18925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SH06_RS18935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SH06_RS18940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SH06_RS18945	COG4974	Belongs to the 'phage' integrase family
SH06_RS18950	COG0716	FMN binding
SH06_RS18960	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
SH06_RS18970	COG1272	protein, Hemolysin III
SH06_RS18980	COG2723	6-phospho-beta-galactosidase activity
SH06_RS18985	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS19005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SH06_RS19010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SH06_RS19015	COG0006	proline dipeptidase activity
SH06_RS19030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SH06_RS19035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SH06_RS19055	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SH06_RS19055	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SH06_RS19060	COG1703	isobutyryl-CoA mutase activity
SH06_RS19065	COG1024	Enoyl-CoA hydratase
SH06_RS19070	COG0427	acetyl-CoA hydrolase
SH06_RS19075	COG0583	DNA-binding transcription factor activity
SH06_RS19080	COG2968	Membrane
SH06_RS19085	COG1279	arginine transmembrane transporter activity
SH06_RS19090	COG0668	transmembrane transport
SH06_RS19095	COG0191	fructose-bisphosphate aldolase activity
SH06_RS19110	COG1072	(Pantothenic acid kinase))
SH06_RS19115	COG3722	fumarate hydratase activity
SH06_RS19120	COG1494	fructose-1,6-bisphosphatase
SH06_RS19125	COG1063	alcohol dehydrogenase
SH06_RS19130	COG2213	PTS system mannitol-specific
SH06_RS19135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS19140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SH06_RS19145	COG0501	Belongs to the peptidase M48B family
SH06_RS19155	COG1166	arginine decarboxylase activity
SH06_RS19190	COG2356	endonuclease I
SH06_RS19195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SH06_RS19200	COG0189	ligase activity
SH06_RS19215	COG2805	Type II/IV secretion system protein
SH06_RS19220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SH06_RS19225	COG0762	integral membrane protein
SH06_RS19235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SH06_RS19240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SH06_RS19250	COG0252	asparaginase activity
SH06_RS19265	COG3171	Protein conserved in bacteria
SH06_RS19275	COG1194	a g-specific adenine glycosylase
SH06_RS19290	COG2211	Major facilitator Superfamily
SH06_RS19295	COG1982	Orn Lys Arg decarboxylase major
SH06_RS19300	COG1811	Na channel or pump
SH06_RS19310	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
SH06_RS19320	COG3031	protein transport across the cell outer membrane
SH06_RS19330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SH06_RS19335	COG3064	Membrane
SH06_RS19345	COG1620	l-lactate permease
SH06_RS19350	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SH06_RS19355	COG3193	protein, possibly involved in utilization of glycolate and propanediol
SH06_RS19360	COG0247	lactate metabolic process
SH06_RS19365	COG0277	FAD linked oxidase domain protein
SH06_RS19370	COG0277	FAD linked oxidase domain protein
SH06_RS19375	COG2186	Transcriptional regulator
SH06_RS19380	COG0456	acetyltransferase
SH06_RS19390	COG2244	polysaccharide biosynthetic process
SH06_RS19395	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SH06_RS19400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SH06_RS19405	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SH06_RS19410	COG0306	phosphate transporter
SH06_RS19415	COG0754	glutathionylspermidine amidase activity
SH06_RS19420	COG0625	glutathione transferase activity
SH06_RS19425	COG0298	carbon dioxide binding
SH06_RS19435	COG1773	rubredoxin
SH06_RS19440	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SH06_RS19445	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SH06_RS19450	COG5557	Pfam Polysulphide reductase, NrfD
SH06_RS19455	COG0437	4 iron, 4 sulfur cluster binding
SH06_RS19460	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SH06_RS19480	COG0667	Aldo Keto reductase
SH06_RS19490	COG1028	Short-chain dehydrogenase reductase Sdr
SH06_RS19495	COG0848	biopolymer transport protein
SH06_RS19500	COG0811	peptide transport
SH06_RS19510	COG0626	cystathionine gamma-synthase activity
SH06_RS19515	COG0586	Pfam SNARE associated Golgi protein
SH06_RS19520	COG2207	Transcriptional regulator
SH06_RS19530	COG1979	alcohol dehydrogenase
SH06_RS19535	COG0656	L-ascorbic acid biosynthetic process
SH06_RS19545	COG4238	major outer membrane lipoprotein
SH06_RS19550	COG1032	radical SAM domain protein
SH06_RS19555	COG2132	Multicopper oxidase
SH06_RS19560	COG0204	Acyl-transferase
SH06_RS19565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SH06_RS19570	COG4166	transmembrane transport
SH06_RS19575	COG2944	sequence-specific DNA binding
SH06_RS19585	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
SH06_RS19590	COG3111	PFAM Bacterial OB fold (BOF) protein
SH06_RS19595	COG0745	RESPONSE REGULATOR receiver
SH06_RS19600	COG0642	Histidine kinase
SH06_RS19610	COG2249	NAD(P)H dehydrogenase (quinone) activity
SH06_RS19615	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SH06_RS19620	COG0187	DNA topoisomerase II activity
SH06_RS19625	COG3150	esterase
SH06_RS19630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SH06_RS19635	COG3151	Protein conserved in bacteria
SH06_RS19640	COG0494	nUDIX hydrolase
SH06_RS19645	COG1538	Outer membrane efflux protein
SH06_RS19660	COG0754	glutathionylspermidine amidase activity
SH06_RS19665	COG3384	dioxygenase
SH06_RS19685	COG2960	long-chain fatty acid transporting porin activity
SH06_RS19690	COG3539	Fimbrial protein
SH06_RS19705	COG3188	usher protein
SH06_RS19710	COG3121	Chaperone
SH06_RS19715	COG3539	Fimbrial protein
SH06_RS19725	COG1585	Membrane protein implicated in regulation of membrane protease activity
SH06_RS19730	COG2268	Band 7 protein
SH06_RS19755	COG3025	triphosphatase activity
SH06_RS19765	COG4991	sh3 domain protein
SH06_RS19780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SH06_RS19790	COG0583	DNA-binding transcription factor activity
SH06_RS19795	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SH06_RS19805	COG0471	metal ion transport
SH06_RS19815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SH06_RS19820	COG0358	DNA primase activity
SH06_RS19825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SH06_RS19840	COG2375	cellular response to nickel ion
SH06_RS19845	COG1695	Transcriptional regulator
SH06_RS19850	COG0840	transmembrane signaling receptor activity
SH06_RS19860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SH06_RS19865	COG1609	Transcriptional regulator
SH06_RS19870	COG3250	beta-galactosidase activity
SH06_RS19875	COG2731	YhcH YjgK YiaL family protein
SH06_RS19880	COG0531	amino acid
SH06_RS19890	COG3408	Glycogen debranching enzyme
SH06_RS19890	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SH06_RS19895	COG1902	pentaerythritol trinitrate reductase activity
SH06_RS19895	COG0446	pyridine nucleotide-disulphide oxidoreductase
SH06_RS19900	COG5499	transcription regulator containing HTH domain
SH06_RS19905	COG4680	protein conserved in bacteria
SH06_RS19920	COG1451	nucleotide metabolic process
SH06_RS19925	COG2949	membrane
SH06_RS19930	COG0673	inositol 2-dehydrogenase activity
SH06_RS19935	COG0861	Integral membrane protein TerC family
SH06_RS19940	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
SH06_RS19950	COG2721	sulfolactate sulfo-lyase activity
SH06_RS19960	COG2271	Major facilitator Superfamily
SH06_RS19965	COG2186	Transcriptional regulator
SH06_RS19970	COG0586	Pfam SNARE associated Golgi protein
SH06_RS19980	COG1422	Protein of unknown function (DUF1090)
SH06_RS19985	COG4575	ribosome binding
SH06_RS19990	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
SH06_RS20000	COG2259	Doxx family
SH06_RS20005	COG0435	Glutathione S-transferase
SH06_RS20010	COG3152	Membrane
SH06_RS20015	COG3152	Membrane
SH06_RS20020	COG0583	DNA-binding transcription factor activity
SH06_RS20025	COG1741	Belongs to the pirin family
SH06_RS20040	COG0814	amino acid
SH06_RS20045	COG1760	l-serine dehydratase
SH06_RS20050	COG0251	oxidation-reduction process
SH06_RS20055	COG1882	Formate acetyltransferase
SH06_RS20070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SH06_RS20080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SH06_RS20085	COG0583	DNA-binding transcription factor activity
SH06_RS20105	COG1929	Belongs to the glycerate kinase type-1 family
SH06_RS20110	COG2084	Dehydrogenase
SH06_RS20120	COG2271	Major facilitator Superfamily
SH06_RS20125	COG2721	sulfolactate sulfo-lyase activity
SH06_RS20130	COG2002	toxin-antitoxin pair type II binding
SH06_RS20140	COG1349	DNA-binding transcription factor activity
SH06_RS20150	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS20160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SH06_RS20165	COG2222	sugar isomerase
SH06_RS20175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS20180	COG3715	PTS system
SH06_RS20185	COG3716	PTS system mannose fructose sorbose family IID component
SH06_RS20190	COG0363	glucosamine-6-phosphate deaminase activity
SH06_RS20195	COG3539	Fimbrial protein
SH06_RS20200	COG3121	Chaperone
SH06_RS20205	COG3188	usher protein
SH06_RS20210	COG3539	Fimbrial protein
SH06_RS20215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SH06_RS20220	COG3107	peptidoglycan biosynthetic process
SH06_RS20235	COG2823	Periplasmic or secreted lipoprotein
SH06_RS20240	COG0701	Predicted permease
SH06_RS20245	COG0702	epimerase
SH06_RS20250	COG0693	protein deglycase activity
SH06_RS20265	COG3153	acetyltransferase
SH06_RS20270	COG3154	lipid carrier protein
SH06_RS20275	COG0826	peptidase U32
SH06_RS20280	COG0826	peptidase U32
SH06_RS20285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SH06_RS20290	COG0814	amino acid
SH06_RS20300	COG0513	Belongs to the DEAD box helicase family
SH06_RS20335	COG0195	Participates in both transcription termination and antitermination
SH06_RS20355	COG2194	sulfuric ester hydrolase activity
SH06_RS20365	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SH06_RS20375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SH06_RS20380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SH06_RS20390	COG1534	Rna-binding protein
SH06_RS20395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SH06_RS20400	COG2027	D-alanyl-D-alanine carboxypeptidase
SH06_RS20410	COG0697	spore germination
SH06_RS20425	COG0142	geranyltranstransferase activity
SH06_RS20430	COG3423	Transcriptional regulator
SH06_RS20440	COG5007	Belongs to the BolA IbaG family
SH06_RS20445	COG3113	response to antibiotic
SH06_RS20450	COG2854	intermembrane phospholipid transfer
SH06_RS20455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SH06_RS20460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SH06_RS20465	COG1127	ABC transporter
SH06_RS20470	COG0530	calcium, potassium:sodium antiporter activity
SH06_RS20475	COG0517	IMP dehydrogenase activity
SH06_RS20475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SH06_RS20480	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SH06_RS20485	COG3117	lipopolysaccharide transmembrane transporter activity
SH06_RS20490	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
SH06_RS20495	COG1137	ATPase activity
SH06_RS20500	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SH06_RS20505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SH06_RS20520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SH06_RS20525	COG0515	serine threonine protein kinase
SH06_RS20540	COG3539	Fimbrial protein
SH06_RS20545	COG4804	nuclease activity
SH06_RS20550	COG2731	YhcH YjgK YiaL family protein
SH06_RS20580	COG3069	C4-dicarboxylate transmembrane transporter activity
SH06_RS20585	COG2969	positive regulation of protein catabolic process
SH06_RS20590	COG0625	glutathione transferase activity
SH06_RS20605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SH06_RS20610	COG3105	Protein conserved in bacteria
SH06_RS20615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SH06_RS20620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SH06_RS20640	COG2732	(Barnase) inhibitor
SH06_RS20660	COG0583	DNA-binding transcription factor activity
SH06_RS20665	COG0312	modulator of DNA gyrase
SH06_RS20670	COG3164	Protein of unknown function
SH06_RS20675	COG1530	ribonuclease E activity
SH06_RS20680	COG0424	maF-like protein
SH06_RS20685	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
SH06_RS20690	COG1792	Involved in formation and maintenance of cell shape
SH06_RS20695	COG1077	Cell shape determining protein MreB Mrl
SH06_RS20705	COG2200	EAL domain
SH06_RS20705	COG2199	diguanylate cyclase activity
SH06_RS20710	COG0604	alcohol dehydrogenase
SH06_RS20730	COG0511	ligase activity, forming carbon-carbon bonds
SH06_RS20735	COG0439	Biotin carboxylase
SH06_RS20740	COG3924	membrane
SH06_RS20745	COG4145	pantothenate transmembrane transporter activity
SH06_RS20755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SH06_RS20765	COG2189	Belongs to the N(4) N(6)-methyltransferase family
SH06_RS20775	COG1309	transcriptional regulator
SH06_RS20780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SH06_RS20785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SH06_RS20800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SH06_RS20805	COG4597	amino acid ABC transporter
SH06_RS20810	COG0765	amino acid transport
SH06_RS20815	COG1126	abc transporter atp-binding protein
SH06_RS20855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SH06_RS20875	COG0551	DNA topoisomerase type I activity
SH06_RS20885	COG0758	DNA mediated transformation
SH06_RS20905	COG0569	domain protein
SH06_RS20915	COG3036	rescue of stalled ribosome
SH06_RS20920	COG0789	Transcriptional regulator
SH06_RS20960	COG0201	protein transport
SH06_RS21050	COG0089	rRNA binding
SH06_RS21075	COG3267	Type II secretory pathway component ExeA
SH06_RS21075	COG3409	Peptidoglycan-binding domain 1 protein
SH06_RS21080	COG3031	protein transport across the cell outer membrane
SH06_RS21085	COG1450	Type ii and iii secretion system protein
SH06_RS21090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SH06_RS21095	COG1459	type II secretion system
SH06_RS21100	COG2165	general secretion pathway protein
SH06_RS21105	COG2165	general secretion pathway protein
SH06_RS21110	COG2165	general secretion pathway protein
SH06_RS21115	COG4795	General secretion pathway protein
SH06_RS21120	COG3156	type II secretion system protein K
SH06_RS21125	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
SH06_RS21130	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
SH06_RS21135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SH06_RS21140	COG2193	ferroxidase activity
SH06_RS21145	COG2906	2 iron, 2 sulfur cluster binding
SH06_RS21150	COG3979	chitinase
SH06_RS21190	COG2964	Protein conserved in bacteria
SH06_RS21195	COG0545	Peptidyl-prolyl cis-trans isomerase
SH06_RS21205	COG1047	Peptidyl-prolyl cis-trans
SH06_RS21210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
SH06_RS21225	COG0488	(ABC) transporter
SH06_RS21230	COG0429	hydrolase of the alpha beta-hydrolase fold
SH06_RS21240	COG3954	Phosphoribulokinase
SH06_RS21245	COG1765	OsmC-like protein
SH06_RS21255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SH06_RS21260	COG1289	transmembrane transporter activity
SH06_RS21265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SH06_RS21270	COG0512	Glutamine amidotransferase of anthranilate synthase
SH06_RS21275	COG2184	nucleotidyltransferase activity
SH06_RS21285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SH06_RS21295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SH06_RS21300	COG2146	nitrite reductase [NAD(P)H] activity
SH06_RS21305	COG2116	formate transmembrane transporter activity
SH06_RS21320	COG0531	amino acid
SH06_RS21325	COG2222	sugar isomerase
SH06_RS21330	COG1082	Xylose isomerase domain protein TIM barrel
SH06_RS21335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SH06_RS21340	COG2188	Transcriptional regulator
SH06_RS21345	COG0626	cystathionine gamma-synthase activity
SH06_RS21360	COG1735	metal-dependent hydrolase with the TIM-barrel fold
SH06_RS21365	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SH06_RS21370	COG3457	Alanine racemase
SH06_RS21380	COG2188	Transcriptional regulator
SH06_RS21385	COG0180	Tryptophanyl-tRNA synthetase
SH06_RS21390	COG0546	phosphoglycolate phosphatase activity
SH06_RS21395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SH06_RS21400	COG0338	D12 class N6 adenine-specific DNA methyltransferase
SH06_RS21405	COG3266	domain, Protein
SH06_RS21420	COG4796	Type ii and iii secretion system protein
SH06_RS21435	COG3166	PFAM Fimbrial assembly family protein
SH06_RS21440	COG4972	Pilus assembly protein
SH06_RS21445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SH06_RS21450	COG0494	nUDIX hydrolase
SH06_RS21460	COG1011	Hydrolase
SH06_RS21465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SH06_RS21475	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
SH06_RS21500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SH06_RS21505	COG2183	response to ionizing radiation
SH06_RS21510	COG1918	ferrous iron import across plasma membrane
SH06_RS21515	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SH06_RS21525	COG5464	transposase or invertase
SH06_RS21535	COG1040	competence protein
SH06_RS21545	COG2610	gluconate transmembrane transporter activity
SH06_RS21550	COG1640	4-alpha-glucanotransferase
SH06_RS21555	COG0058	SHG alpha-glucan phosphorylase activity
SH06_RS21570	COG1690	Belongs to the RtcB family
SH06_RS21575	COG4650	regulator
SH06_RS21580	COG1349	DNA-binding transcription factor activity
SH06_RS21595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SH06_RS21600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SH06_RS21605	COG0058	SHG alpha-glucan phosphorylase activity
SH06_RS21630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SH06_RS21635	COG2095	MarC family integral membrane protein
SH06_RS21640	COG2610	gluconate transmembrane transporter activity
SH06_RS21645	COG3265	gluconokinase activity
SH06_RS21650	COG1609	Transcriptional regulator
SH06_RS21655	COG1741	Belongs to the pirin family
SH06_RS21660	COG0673	inositol 2-dehydrogenase activity
SH06_RS21665	COG1247	-acetyltransferase
SH06_RS21670	COG3157	Type VI secretion system effector, Hcp
SH06_RS21690	COG0405	Gamma-glutamyltransferase
SH06_RS21700	COG0584	glycerophosphoryl diester phosphodiesterase
SH06_RS21705	COG3842	ATPase activity
SH06_RS21710	COG0395	ABC-type sugar transport system, permease component
SH06_RS21715	COG1175	transmembrane transport
SH06_RS21720	COG1653	transport
SH06_RS21730	COG0410	ABC transporter
SH06_RS21735	COG0411	ABC transporter
SH06_RS21740	COG4177	L-phenylalanine transmembrane transporter activity
SH06_RS21745	COG0559	Belongs to the binding-protein-dependent transport system permease family
SH06_RS21750	COG0683	leucine binding
SH06_RS21755	COG0456	acetyltransferase
SH06_RS21765	COG0683	leucine binding
SH06_RS21770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SH06_RS21775	COG2177	Part of the ABC transporter FtsEX involved in
SH06_RS21780	COG2884	Cell division ATP-binding protein ftsE
SH06_RS21785	COG0552	protein localization to endoplasmic reticulum
SH06_RS21790	COG0742	ribosomal rna small subunit methyltransferase
SH06_RS21795	COG3776	membrane
SH06_RS21805	COG3714	YhhN family
SH06_RS21810	COG2217	Heavy metal translocating P-type atpase
SH06_RS21820	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SH06_RS21830	COG0477	Major facilitator Superfamily
SH06_RS21835	COG0628	permease
SH06_RS21840	COG2091	lysine biosynthetic process via aminoadipic acid
SH06_RS21845	COG0747	negative chemotaxis
SH06_RS21850	COG0601	transmembrane transport
SH06_RS21855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SH06_RS21860	COG0444	Belongs to the ABC transporter superfamily
SH06_RS21865	COG1124	(ABC) transporter
SH06_RS21875	COG3209	COG3209 Rhs family protein
SH06_RS21890	COG5433	transposase activity
SH06_RS21895	COG0842	Transport permease protein
SH06_RS21900	COG0842	Transport permease protein
SH06_RS21900	COG1129	ABC transporter
SH06_RS21905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SH06_RS21935	COG2081	HI0933 family
SH06_RS21940	COG0306	phosphate transporter
SH06_RS21950	COG0589	response to stress
SH06_RS21955	COG3104	oligopeptide transport
SH06_RS21965	COG0339	signal peptide processing
SH06_RS21970	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
SH06_RS21975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SH06_RS21990	COG0640	Transcriptional regulator
SH06_RS21995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SH06_RS22000	COG1393	Belongs to the ArsC family
SH06_RS22020	COG3065	identical protein binding
SH06_RS22025	COG2197	response regulator
SH06_RS22030	COG1285	pathogenesis
SH06_RS22045	COG3247	response to pH
SH06_RS22050	COG2771	luxR family
SH06_RS22060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SH06_RS22065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SH06_RS22070	COG2207	Transcriptional regulator
SH06_RS22075	COG2207	Transcriptional regulator
SH06_RS22080	COG0076	glutamate decarboxylase activity
SH06_RS22085	COG1858	cytochrome C peroxidase
SH06_RS22095	COG2197	response regulator
SH06_RS22100	COG0583	DNA-binding transcription factor activity
SH06_RS22105	COG1295	ribonuclease BN
SH06_RS22110	COG0477	Major facilitator Superfamily
SH06_RS22115	COG2982	Protein involved in outer membrane biogenesis
SH06_RS22120	COG2200	EAL domain
SH06_RS22130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SH06_RS22135	COG0612	Peptidase, M16
SH06_RS22145	COG2199	diguanylate cyclase activity
SH06_RS22145	COG2200	EAL domain
SH06_RS22150	COG3118	belongs to the thioredoxin family
SH06_RS22150	COG0457	Tetratricopeptide repeat
SH06_RS22155	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SH06_RS22160	COG1215	transferase activity, transferring glycosyl groups
SH06_RS22165	COG1215	transferase activity, transferring glycosyl groups
SH06_RS22195	COG2194	sulfuric ester hydrolase activity
SH06_RS22210	COG0814	amino acid
SH06_RS22215	COG4608	Belongs to the ABC transporter superfamily
SH06_RS22220	COG0444	Belongs to the ABC transporter superfamily
SH06_RS22225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SH06_RS22230	COG0601	transmembrane transport
SH06_RS22240	COG0747	negative chemotaxis
SH06_RS22255	COG2194	sulfuric ester hydrolase activity
SH06_RS22260	COG2223	nitrite transmembrane transporter activity
SH06_RS22265	COG5571	outer membrane autotransporter
SH06_RS22270	COG2818	Glycosylase
SH06_RS22275	COG0456	acetyltransferase
SH06_RS22280	COG0243	molybdopterin cofactor binding
SH06_RS22285	COG2885	chlorophyll binding
SH06_RS22300	COG2944	sequence-specific DNA binding
SH06_RS22305	COG1278	Cold shock
SH06_RS22315	COG2963	transposase activity
SH06_RS22320	COG2801	Transposase and inactivated derivatives
SH06_RS22340	COG3274	enterobacterial common antigen metabolic process
SH06_RS22345	COG4682	membrane
SH06_RS22350	COG4682	membrane
SH06_RS22355	COG1070	Carbohydrate kinase
SH06_RS22365	COG4213	ABC transporter substrate-binding protein
SH06_RS22375	COG4213	ABC transporter substrate-binding protein
SH06_RS22380	COG1129	ABC transporter
SH06_RS22385	COG4214	carbohydrate transport
SH06_RS22390	COG2207	Transcriptional regulator
SH06_RS22390	COG1609	Transcriptional regulator
SH06_RS22395	COG2992	FlgJ-related protein
SH06_RS22400	COG0366	Alpha amylase catalytic
SH06_RS22405	COG3977	Valine--pyruvate aminotransferase
SH06_RS22415	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SH06_RS22420	COG1414	Transcriptional regulator
SH06_RS22430	COG2731	YhcH YjgK YiaL family protein
SH06_RS22435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SH06_RS22440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SH06_RS22445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SH06_RS22450	COG1070	Carbohydrate kinase
SH06_RS22455	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SH06_RS22460	COG3623	hexulose-6-phosphate isomerase
SH06_RS22465	COG0235	Class ii aldolase
SH06_RS22470	COG3713	MltA-interacting MipA family protein
SH06_RS22475	COG0583	DNA-binding transcription factor activity
SH06_RS22480	COG1566	PFAM secretion protein HlyD family protein
SH06_RS22495	COG1012	belongs to the aldehyde dehydrogenase family
SH06_RS22500	COG1454	alcohol dehydrogenase
SH06_RS22505	COG3276	selenocysteine insertion sequence binding
SH06_RS22515	COG0625	glutathione transferase activity
SH06_RS22520	COG3209	COG3209 Rhs family protein
SH06_RS22525	COG1413	lyase activity
SH06_RS22530	COG3209	COG3209 Rhs family protein
SH06_RS22535	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SH06_RS22545	COG1566	PFAM secretion protein HlyD family protein
SH06_RS22565	COG3722	fumarate hydratase activity
SH06_RS22580	COG1620	l-lactate permease
SH06_RS22585	COG2186	Transcriptional regulator
SH06_RS22595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SH06_RS22600	COG1045	serine acetyltransferase
SH06_RS22615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SH06_RS22620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SH06_RS22625	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SH06_RS22630	COG4942	peptidase
SH06_RS22635	COG2861	carbohydrate metabolic process
SH06_RS22640	COG1216	Glycosyl transferase, family 2
SH06_RS22650	COG0156	8-amino-7-oxononanoate synthase activity
SH06_RS22665	COG0859	PFAM glycosyl transferase family 9
SH06_RS22670	COG0859	PFAM glycosyl transferase family 9
SH06_RS22675	COG3307	-O-antigen
SH06_RS22680	COG0859	PFAM glycosyl transferase family 9
SH06_RS22690	COG3642	lipopolysaccharide core region biosynthetic process
SH06_RS22695	COG1442	glycosyl transferase family 8
SH06_RS22700	COG1442	glycosyl transferase family 8
SH06_RS22705	COG0438	transferase activity, transferring glycosyl groups
SH06_RS22710	COG4641	Protein conserved in bacteria
SH06_RS22710	COG0438	transferase activity, transferring glycosyl groups
SH06_RS22715	COG0515	serine threonine protein kinase
SH06_RS22720	COG0438	transferase activity, transferring glycosyl groups
SH06_RS22725	COG0859	PFAM glycosyl transferase family 9
SH06_RS22730	COG1519	Transferase
SH06_RS22760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SH06_RS22765	COG0756	dUTP diphosphatase activity
SH06_RS22785	COG1561	YicC-like family, N-terminal region
SH06_RS22790	COG3645	SOS response
SH06_RS22795	COG2860	membrane
SH06_RS22805	COG0194	GDP metabolic process
SH06_RS22815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SH06_RS22820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SH06_RS22825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SH06_RS22830	COG0786	glutamate:sodium symporter activity
SH06_RS22835	COG2233	PERMEase
SH06_RS22840	COG2982	Protein involved in outer membrane biogenesis
SH06_RS22845	COG1501	Belongs to the glycosyl hydrolase 31 family
SH06_RS22850	COG2211	Major facilitator Superfamily
SH06_RS22865	COG2814	Major facilitator Superfamily
SH06_RS22870	COG0697	spore germination
SH06_RS22875	COG1464	Belongs to the NlpA lipoprotein family
SH06_RS22900	COG2252	PERMEase
SH06_RS22910	COG2271	Major facilitator Superfamily
SH06_RS22915	COG2271	Major facilitator Superfamily
SH06_RS22920	COG3851	Histidine kinase
SH06_RS22925	COG2197	response regulator
SH06_RS22930	COG0440	acetolactate synthase activity
SH06_RS22935	COG0028	Belongs to the TPP enzyme family
SH06_RS22960	COG2814	Major facilitator Superfamily
SH06_RS22965	COG0641	radical SAM
SH06_RS22975	COG2149	membrane
SH06_RS22985	COG3119	arylsulfatase activity
SH06_RS22990	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SH06_RS22995	COG2207	Transcriptional regulator
SH06_RS23005	COG1263	PTS System
SH06_RS23005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SH06_RS23010	COG1263	PTS System
SH06_RS23015	COG2188	Transcriptional regulator
SH06_RS23035	COG5645	(Lipo)protein
SH06_RS23040	COG0823	Involved in the tonB-independent uptake of proteins
SH06_RS23045	COG0644	oxidoreductase
SH06_RS23050	COG2271	Major facilitator Superfamily
SH06_RS23060	COG0800	Aldolase
SH06_RS23065	COG3734	2-keto-3-deoxy-galactonokinase
SH06_RS23070	COG2186	Transcriptional regulator
SH06_RS23080	COG0561	phosphatase activity
SH06_RS23085	COG3753	Protein conserved in bacteria
SH06_RS23095	COG0187	DNA topoisomerase II activity
SH06_RS23105	COG0592	DNA-directed DNA polymerase activity
SH06_RS23190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction