locus-tag	class	description
BZY74_RS00140	COG0582	viral genome integration into host DNA
BZY74_RS00240	COG1783	phage Terminase large subunit
BZY74_RS00255	COG3646	Phage regulatory protein
BZY74_RS00460	COG0477	Major facilitator Superfamily
BZY74_RS00465	COG1566	PFAM secretion protein HlyD family protein
BZY74_RS00470	COG2197	response regulator
BZY74_RS00475	COG2205	protein histidine kinase activity
BZY74_RS00475	COG0784	Response regulator, receiver
BZY74_RS00475	COG2198	Histidine kinase
BZY74_RS00475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZY74_RS00480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BZY74_RS00485	COG0679	Auxin Efflux Carrier
BZY74_RS00490	COG0028	Belongs to the TPP enzyme family
BZY74_RS00520	COG1560	Kdo2-lipid A biosynthetic process
BZY74_RS00530	COG0436	Aminotransferase
BZY74_RS00535	COG3275	phosphorelay sensor kinase activity
BZY74_RS00540	COG3279	Response regulator of the LytR AlgR family
BZY74_RS00545	COG2207	Transcriptional regulator
BZY74_RS00555	COG1363	Peptidase, m42
BZY74_RS00560	COG0006	proline dipeptidase activity
BZY74_RS00565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS00570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS00595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZY74_RS00600	COG2200	EAL domain
BZY74_RS00600	COG2199	diguanylate cyclase activity
BZY74_RS00615	COG3415	Transposase
BZY74_RS00620	COG3415	Transposase
BZY74_RS00660	COG0583	DNA-binding transcription factor activity
BZY74_RS00665	COG0385	Bile acid
BZY74_RS00670	COG3530	Putative quorum-sensing-regulated virulence factor
BZY74_RS00690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZY74_RS00695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS00700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZY74_RS00705	COG2190	(PTS) system
BZY74_RS00720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZY74_RS00725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BZY74_RS00730	COG4208	sulfate ABC transporter
BZY74_RS00735	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BZY74_RS00740	COG4150	thiosulfate binding
BZY74_RS00745	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS00760	COG1263	PTS System
BZY74_RS00760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS00765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BZY74_RS00770	COG2837	iron assimilation
BZY74_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZY74_RS00800	COG2207	Transcriptional regulator
BZY74_RS00805	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BZY74_RS00810	COG4816	utilization protein
BZY74_RS00820	COG4303	Ethanolamine ammonia lyase large subunit
BZY74_RS00825	COG4819	ethanolamine utilization protein
BZY74_RS00830	COG3192	ethanolamine utilization protein
BZY74_RS00835	COG1454	alcohol dehydrogenase
BZY74_RS00840	COG4820	ethanolamine utilization protein (EutJ)
BZY74_RS00845	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS00850	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BZY74_RS00855	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BZY74_RS00860	COG0280	phosphate acetyltransferase
BZY74_RS00865	COG4812	Cobalamin adenosyltransferase
BZY74_RS00870	COG4766	ethanolamine catabolic process
BZY74_RS00875	COG4917	ethanolamine utilization protein
BZY74_RS00880	COG4810	utilization protein
BZY74_RS00885	COG0281	malic enzyme
BZY74_RS00885	COG0280	phosphate acetyltransferase
BZY74_RS00895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZY74_RS00900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BZY74_RS00905	COG5342	invasion associated locus B
BZY74_RS00915	COG0493	'glutamate synthase
BZY74_RS00915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS00920	COG3850	Histidine kinase
BZY74_RS00925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZY74_RS00940	COG1393	Belongs to the ArsC family
BZY74_RS00955	COG0400	carboxylic ester hydrolase activity
BZY74_RS00960	COG1444	tRNA N-acetyltransferase activity
BZY74_RS00965	COG2321	neutral zinc metallopeptidase
BZY74_RS00985	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BZY74_RS00995	COG2716	regulation of RNA biosynthetic process
BZY74_RS01000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BZY74_RS01005	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS01010	COG0651	ATP synthesis coupled electron transport
BZY74_RS01015	COG0650	Formate hydrogenlyase subunit 4
BZY74_RS01025	COG4237	Hydrogenase 4 membrane
BZY74_RS01030	COG0651	ATP synthesis coupled electron transport
BZY74_RS01035	COG3261	NADH dehydrogenase
BZY74_RS01035	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BZY74_RS01040	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZY74_RS01045	COG3260	NADH ubiquinone oxidoreductase 20
BZY74_RS01055	COG3604	Transcriptional regulator
BZY74_RS01070	COG0628	permease
BZY74_RS01075	COG4783	chaperone-mediated protein folding
BZY74_RS01080	COG1393	Belongs to the ArsC family
BZY74_RS01090	COG2233	PERMEase
BZY74_RS01110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BZY74_RS01115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BZY74_RS01120	COG0248	Ppx GppA phosphatase
BZY74_RS01125	COG2200	EAL domain
BZY74_RS01145	COG3133	Outer membrane lipoprotein
BZY74_RS01160	COG0556	nucleotide-excision repair
BZY74_RS01190	COG5314	conjugation
BZY74_RS01225	COG0582	viral genome integration into host DNA
BZY74_RS01235	COG0516	GMP reductase activity
BZY74_RS01235	COG0517	IMP dehydrogenase activity
BZY74_RS01245	COG1645	bacterial-type flagellum-dependent swarming motility
BZY74_RS01260	COG2976	Protein conserved in bacteria
BZY74_RS01290	COG4953	penicillin-binding protein 1C
BZY74_RS01300	COG2897	thiosulfate sulfurtransferase activity
BZY74_RS01315	COG2975	iron-sulfur cluster assembly
BZY74_RS01320	COG0633	Ferredoxin
BZY74_RS01340	COG0822	iron-sulfur transferase activity
BZY74_RS01360	COG0483	inositol monophosphate 1-phosphatase activity
BZY74_RS01365	COG1073	alpha beta
BZY74_RS01370	COG3711	transcriptional antiterminator
BZY74_RS01375	COG2814	Major facilitator Superfamily
BZY74_RS01380	COG0583	DNA-binding transcription factor activity
BZY74_RS01385	COG4638	Rieske (2fe-2S)
BZY74_RS01410	COG2259	Doxx family
BZY74_RS01415	COG2017	converts alpha-aldose to the beta-anomer
BZY74_RS01420	COG1063	alcohol dehydrogenase
BZY74_RS01425	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZY74_RS01430	COG1129	ABC transporter
BZY74_RS01435	COG1879	ABC-type sugar transport system periplasmic component
BZY74_RS01440	COG0457	Tetratricopeptide repeat
BZY74_RS01445	COG1940	carbohydrate kinase activity
BZY74_RS01455	COG1017	nitric oxide dioxygenase activity
BZY74_RS01455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZY74_RS01460	COG0347	Belongs to the P(II) protein family
BZY74_RS01465	COG2204	response regulator
BZY74_RS01470	COG3170	Tfp pilus assembly protein FimV
BZY74_RS01475	COG2205	protein histidine kinase activity
BZY74_RS01500	COG0560	Phosphoserine phosphatase
BZY74_RS01505	COG1737	Transcriptional regulator
BZY74_RS01510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS01535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BZY74_RS01560	COG0681	Belongs to the peptidase S26 family
BZY74_RS01570	COG3086	response to oxidative stress
BZY74_RS01575	COG3026	antisigma factor binding
BZY74_RS01580	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BZY74_RS01585	COG1595	DNA-templated transcription, initiation
BZY74_RS01590	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BZY74_RS01600	COG0513	Belongs to the DEAD box helicase family
BZY74_RS01605	COG0583	DNA-binding transcription factor activity
BZY74_RS01625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZY74_RS01635	COG3118	belongs to the thioredoxin family
BZY74_RS01640	COG3148	PFAM DTW domain containing protein
BZY74_RS01645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZY74_RS01645	COG1042	CoA-binding domain protein
BZY74_RS01645	COG0045	succinate-CoA ligase (ADP-forming) activity
BZY74_RS01650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BZY74_RS01655	COG5544	Lipoprotein
BZY74_RS01660	COG0477	Major facilitator Superfamily
BZY74_RS01690	COG0542	response to heat
BZY74_RS01695	COG1496	oxidoreductase activity
BZY74_RS01700	COG0564	pseudouridine synthase activity
BZY74_RS01705	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZY74_RS01715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BZY74_RS01720	COG0077	Prephenate dehydratase
BZY74_RS01720	COG1605	Chorismate mutase
BZY74_RS01725	COG1605	Chorismate mutase
BZY74_RS01725	COG0287	Prephenate dehydrogenase
BZY74_RS01730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZY74_RS01745	COG2199	diguanylate cyclase activity
BZY74_RS01750	COG2885	chlorophyll binding
BZY74_RS01775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BZY74_RS01780	COG4137	Cytochrome C assembly protein
BZY74_RS01785	COG4536	flavin adenine dinucleotide binding
BZY74_RS01805	COG0497	DNA recombination
BZY74_RS01810	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZY74_RS01820	COG2867	negative regulation of translational initiation
BZY74_RS01835	COG0582	viral genome integration into host DNA
BZY74_RS01870	COG0579	oxidoreductase
BZY74_RS01875	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS01880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BZY74_RS01885	COG1113	amino acid transport
BZY74_RS01890	COG1802	Transcriptional regulator
BZY74_RS01895	COG1652	LysM domain
BZY74_RS01900	COG0401	homolog of Blt101
BZY74_RS01905	COG0640	Transcriptional regulator
BZY74_RS01910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BZY74_RS01915	COG2916	Histone family protein nucleoid-structuring protein H-NS
BZY74_RS01930	COG4575	ribosome binding
BZY74_RS01935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZY74_RS01945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZY74_RS01950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZY74_RS01955	COG4175	Glycine betaine
BZY74_RS01960	COG4176	ABC-type proline glycine betaine transport system permease component
BZY74_RS01965	COG2113	Glycine betaine
BZY74_RS01970	COG2814	Major facilitator Superfamily
BZY74_RS01975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BZY74_RS01985	COG1846	Transcriptional regulator
BZY74_RS01990	COG1566	PFAM secretion protein HlyD family protein
BZY74_RS01995	COG2814	Major facilitator Superfamily
BZY74_RS02010	COG1238	metal cluster binding
BZY74_RS02015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZY74_RS02040	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BZY74_RS02060	COG1546	Belongs to the CinA family
BZY74_RS02065	COG2951	lytic endotransglycosylase activity
BZY74_RS02070	COG3730	PTS system glucitol sorbitol-specific
BZY74_RS02075	COG3732	PTS system glucitol sorbitol-specific
BZY74_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS02090	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS02095	COG1349	DNA-binding transcription factor activity
BZY74_RS02100	COG0517	IMP dehydrogenase activity
BZY74_RS02100	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BZY74_RS02120	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BZY74_RS02125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS02130	COG1609	Transcriptional regulator
BZY74_RS02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS02135	COG1263	PTS System
BZY74_RS02140	COG2723	6-phospho-beta-galactosidase activity
BZY74_RS02145	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BZY74_RS02155	COG3260	NADH ubiquinone oxidoreductase 20
BZY74_RS02160	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZY74_RS02165	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BZY74_RS02165	COG3261	NADH dehydrogenase
BZY74_RS02170	COG0650	Formate hydrogenlyase subunit 4
BZY74_RS02175	COG0651	ATP synthesis coupled electron transport
BZY74_RS02180	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS02195	COG0375	protein maturation
BZY74_RS02200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BZY74_RS02205	COG0298	carbon dioxide binding
BZY74_RS02210	COG0409	Hydrogenase expression formation protein
BZY74_RS02215	COG0309	Hydrogenase expression formation protein (HypE)
BZY74_RS02220	COG3604	Transcriptional regulator
BZY74_RS02240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BZY74_RS02245	COG1349	DNA-binding transcription factor activity
BZY74_RS02250	COG2084	Dehydrogenase
BZY74_RS02255	COG3395	kinase activity
BZY74_RS02260	COG0235	Class ii aldolase
BZY74_RS02265	COG3622	Belongs to the hyi family
BZY74_RS02270	COG2610	gluconate transmembrane transporter activity
BZY74_RS02280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BZY74_RS02295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZY74_RS02300	COG1388	LysM domain
BZY74_RS02300	COG4942	peptidase
BZY74_RS02355	COG2234	aminopeptidase activity
BZY74_RS02360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BZY74_RS02365	COG1518	maintenance of DNA repeat elements
BZY74_RS02380	COG1857	crispr-associated protein
BZY74_RS02395	COG1203	CRISPR-associated helicase, Cas3
BZY74_RS02420	COG0720	synthase
BZY74_RS02425	COG0644	oxidoreductase
BZY74_RS02430	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BZY74_RS02435	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BZY74_RS02440	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BZY74_RS02445	COG2086	electron transfer activity
BZY74_RS02450	COG0477	Major facilitator Superfamily
BZY74_RS02455	COG0277	FAD linked oxidase domain protein
BZY74_RS02460	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS02465	COG2223	nitrite transmembrane transporter activity
BZY74_RS02470	COG1070	Carbohydrate kinase
BZY74_RS02475	COG0602	queuosine metabolic process
BZY74_RS02500	COG3956	TIGRFAM MazG family protein
BZY74_RS02505	COG2337	Toxic component of a toxin-antitoxin (TA) module
BZY74_RS02510	COG2336	PFAM SpoVT AbrB
BZY74_RS02515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZY74_RS02525	COG2205	protein histidine kinase activity
BZY74_RS02525	COG3850	Histidine kinase
BZY74_RS02525	COG3437	response regulator, receiver
BZY74_RS02525	COG4999	Histidine kinase
BZY74_RS02530	COG4948	Mandelate Racemase Muconate Lactonizing
BZY74_RS02535	COG4948	Mandelate Racemase Muconate Lactonizing
BZY74_RS02540	COG2271	Major facilitator Superfamily
BZY74_RS02545	COG0716	FMN binding
BZY74_RS02550	COG0564	pseudouridine synthase activity
BZY74_RS02555	COG3098	single-species biofilm formation
BZY74_RS02570	COG1611	Belongs to the LOG family
BZY74_RS02575	COG0814	amino acid
BZY74_RS02580	COG1760	l-serine dehydratase
BZY74_RS02590	COG1454	alcohol dehydrogenase
BZY74_RS02595	COG0235	Class ii aldolase
BZY74_RS02600	COG0738	Major facilitator superfamily
BZY74_RS02610	COG1070	Carbohydrate kinase
BZY74_RS02620	COG1349	DNA-binding transcription factor activity
BZY74_RS02630	COG2363	Small membrane protein
BZY74_RS02635	COG0583	DNA-binding transcription factor activity
BZY74_RS02645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BZY74_RS02650	COG2166	iron-sulfur cluster assembly
BZY74_RS02655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BZY74_RS02660	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BZY74_RS02695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BZY74_RS02700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS02700	COG1263	PTS System
BZY74_RS02705	COG3711	transcriptional antiterminator
BZY74_RS02710	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZY74_RS02715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BZY74_RS02715	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BZY74_RS02720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BZY74_RS02725	COG1074	ATP-dependent DNA helicase activity
BZY74_RS02730	COG1025	Belongs to the peptidase M16 family
BZY74_RS02735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BZY74_RS02740	COG4967	type IV pilus modification protein PilV
BZY74_RS02750	COG4795	General secretion pathway protein
BZY74_RS02755	COG2165	general secretion pathway protein
BZY74_RS02770	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BZY74_RS02785	COG0861	Integral membrane protein TerC family
BZY74_RS02795	COG0667	Aldo Keto reductase
BZY74_RS02810	COG1609	Transcriptional regulator
BZY74_RS02820	COG0583	DNA-binding transcription factor activity
BZY74_RS02825	COG1794	racemase activity, acting on amino acids and derivatives
BZY74_RS02830	COG2814	Major facilitator Superfamily
BZY74_RS02835	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS02845	COG0183	Belongs to the thiolase family
BZY74_RS02850	COG0814	amino acid
BZY74_RS02855	COG2771	luxR family
BZY74_RS02860	COG3710	Transcriptional regulator
BZY74_RS02890	COG0457	Tetratricopeptide repeat
BZY74_RS02895	COG0457	Tetratricopeptide repeat
BZY74_RS02895	COG3710	Transcriptional regulator
BZY74_RS02915	COG2197	response regulator
BZY74_RS02920	COG2197	response regulator
BZY74_RS03010	COG3387	PFAM Glycoside hydrolase 15-related
BZY74_RS03020	COG4942	peptidase
BZY74_RS03030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BZY74_RS03035	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BZY74_RS03040	COG2080	2 iron, 2 sulfur cluster binding
BZY74_RS03045	COG3829	transcription factor binding
BZY74_RS03050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BZY74_RS03055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZY74_RS03060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BZY74_RS03070	COG0549	Belongs to the carbamate kinase family
BZY74_RS03075	COG3608	succinylglutamate desuccinylase aspartoacylase
BZY74_RS03075	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BZY74_RS03080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BZY74_RS03085	COG2068	MobA-Related Protein
BZY74_RS03090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS03090	COG0493	'glutamate synthase
BZY74_RS03095	COG0402	S-adenosylhomocysteine deaminase activity
BZY74_RS03100	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BZY74_RS03105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BZY74_RS03105	COG2080	2 iron, 2 sulfur cluster binding
BZY74_RS03110	COG2233	PERMEase
BZY74_RS03115	COG0402	S-adenosylhomocysteine deaminase activity
BZY74_RS03120	COG2252	PERMEase
BZY74_RS03125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS03130	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS03130	COG0493	'glutamate synthase
BZY74_RS03140	COG2233	PERMEase
BZY74_RS03165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BZY74_RS03170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZY74_RS03175	COG4974	Belongs to the 'phage' integrase family
BZY74_RS03180	COG0716	FMN binding
BZY74_RS03190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BZY74_RS03200	COG1272	protein, Hemolysin III
BZY74_RS03210	COG2723	6-phospho-beta-galactosidase activity
BZY74_RS03215	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS03235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZY74_RS03240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZY74_RS03245	COG0006	proline dipeptidase activity
BZY74_RS03270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BZY74_RS03285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BZY74_RS03310	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BZY74_RS03310	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BZY74_RS03315	COG1703	isobutyryl-CoA mutase activity
BZY74_RS03320	COG1024	Enoyl-CoA hydratase
BZY74_RS03325	COG0427	acetyl-CoA hydrolase
BZY74_RS03330	COG0583	DNA-binding transcription factor activity
BZY74_RS03335	COG2968	Membrane
BZY74_RS03340	COG1279	arginine transmembrane transporter activity
BZY74_RS03345	COG0668	transmembrane transport
BZY74_RS03350	COG3547	Transposase (IS116 IS110 IS902 family)
BZY74_RS03360	COG0191	fructose-bisphosphate aldolase activity
BZY74_RS03395	COG1122	ATPase activity
BZY74_RS03400	COG1122	ATPase activity
BZY74_RS03405	COG1072	(Pantothenic acid kinase))
BZY74_RS03415	COG1494	fructose-1,6-bisphosphatase
BZY74_RS03420	COG1063	alcohol dehydrogenase
BZY74_RS03425	COG2213	PTS system mannitol-specific
BZY74_RS03430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS03435	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BZY74_RS03440	COG0501	Belongs to the peptidase M48B family
BZY74_RS03455	COG3716	PTS system mannose fructose sorbose family IID component
BZY74_RS03460	COG3715	PTS system
BZY74_RS03465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS03465	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS03490	COG1166	arginine decarboxylase activity
BZY74_RS03515	COG2814	Major facilitator Superfamily
BZY74_RS03525	COG2356	endonuclease I
BZY74_RS03530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BZY74_RS03535	COG0189	ligase activity
BZY74_RS03550	COG2805	Type II/IV secretion system protein
BZY74_RS03555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BZY74_RS03560	COG0762	integral membrane protein
BZY74_RS03575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZY74_RS03585	COG0252	asparaginase activity
BZY74_RS03595	COG3171	Protein conserved in bacteria
BZY74_RS03610	COG1194	a g-specific adenine glycosylase
BZY74_RS03625	COG2211	Major facilitator Superfamily
BZY74_RS03630	COG1982	Orn Lys Arg decarboxylase major
BZY74_RS03640	COG1811	Na channel or pump
BZY74_RS03650	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BZY74_RS03680	COG2165	general secretion pathway protein
BZY74_RS03685	COG1459	type II secretion system
BZY74_RS03690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BZY74_RS03715	COG3064	Membrane
BZY74_RS03725	COG1620	l-lactate permease
BZY74_RS03730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BZY74_RS03735	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BZY74_RS03740	COG0247	lactate metabolic process
BZY74_RS03750	COG0277	FAD linked oxidase domain protein
BZY74_RS03755	COG2186	Transcriptional regulator
BZY74_RS03760	COG0456	acetyltransferase
BZY74_RS03770	COG0318	PFAM AMP-dependent synthetase and ligase
BZY74_RS03780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BZY74_RS03785	COG0156	8-amino-7-oxononanoate synthase activity
BZY74_RS03795	COG0795	lipopolysaccharide-transporting ATPase activity
BZY74_RS03800	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BZY74_RS03810	COG2244	polysaccharide biosynthetic process
BZY74_RS03815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BZY74_RS03820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BZY74_RS03825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BZY74_RS03830	COG0306	phosphate transporter
BZY74_RS03835	COG0754	glutathionylspermidine amidase activity
BZY74_RS03840	COG0625	glutathione transferase activity
BZY74_RS03845	COG0298	carbon dioxide binding
BZY74_RS03850	COG0375	protein maturation
BZY74_RS03855	COG1773	rubredoxin
BZY74_RS03860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BZY74_RS03865	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BZY74_RS03870	COG5557	Pfam Polysulphide reductase, NrfD
BZY74_RS03875	COG0437	4 iron, 4 sulfur cluster binding
BZY74_RS03880	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BZY74_RS03900	COG0667	Aldo Keto reductase
BZY74_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS03915	COG0848	biopolymer transport protein
BZY74_RS03920	COG0811	peptide transport
BZY74_RS03930	COG0626	cystathionine gamma-synthase activity
BZY74_RS03935	COG0586	Pfam SNARE associated Golgi protein
BZY74_RS03940	COG2207	Transcriptional regulator
BZY74_RS03945	COG1979	alcohol dehydrogenase
BZY74_RS03950	COG0656	L-ascorbic acid biosynthetic process
BZY74_RS03960	COG4238	major outer membrane lipoprotein
BZY74_RS03965	COG1032	radical SAM domain protein
BZY74_RS03970	COG2132	Multicopper oxidase
BZY74_RS03975	COG0204	Acyl-transferase
BZY74_RS03980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BZY74_RS03990	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BZY74_RS03995	COG3111	PFAM Bacterial OB fold (BOF) protein
BZY74_RS04000	COG0745	RESPONSE REGULATOR receiver
BZY74_RS04005	COG0642	Histidine kinase
BZY74_RS04015	COG2249	NAD(P)H dehydrogenase (quinone) activity
BZY74_RS04020	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BZY74_RS04025	COG0187	DNA topoisomerase II activity
BZY74_RS04030	COG3150	esterase
BZY74_RS04035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BZY74_RS04040	COG3151	Protein conserved in bacteria
BZY74_RS04045	COG0494	nUDIX hydrolase
BZY74_RS04050	COG1538	Outer membrane efflux protein
BZY74_RS04065	COG0754	glutathionylspermidine amidase activity
BZY74_RS04070	COG3384	dioxygenase
BZY74_RS04090	COG2960	long-chain fatty acid transporting porin activity
BZY74_RS04095	COG3539	Fimbrial protein
BZY74_RS04100	COG3188	usher protein
BZY74_RS04105	COG3121	Chaperone
BZY74_RS04110	COG3539	Fimbrial protein
BZY74_RS04120	COG1585	Membrane protein implicated in regulation of membrane protease activity
BZY74_RS04125	COG2268	Band 7 protein
BZY74_RS04145	COG3025	triphosphatase activity
BZY74_RS04155	COG4991	sh3 domain protein
BZY74_RS04170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BZY74_RS04180	COG0583	DNA-binding transcription factor activity
BZY74_RS04190	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BZY74_RS04195	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BZY74_RS04200	COG0471	metal ion transport
BZY74_RS04210	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BZY74_RS04215	COG0358	DNA primase activity
BZY74_RS04225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZY74_RS04240	COG2375	cellular response to nickel ion
BZY74_RS04250	COG1695	Transcriptional regulator
BZY74_RS04255	COG0840	transmembrane signaling receptor activity
BZY74_RS04270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZY74_RS04280	COG1609	Transcriptional regulator
BZY74_RS04285	COG3250	beta-galactosidase activity
BZY74_RS04290	COG2731	YhcH YjgK YiaL family protein
BZY74_RS04295	COG0531	amino acid
BZY74_RS04305	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BZY74_RS04305	COG3408	Glycogen debranching enzyme
BZY74_RS04310	COG0446	pyridine nucleotide-disulphide oxidoreductase
BZY74_RS04310	COG1902	pentaerythritol trinitrate reductase activity
BZY74_RS04315	COG5499	transcription regulator containing HTH domain
BZY74_RS04320	COG4680	protein conserved in bacteria
BZY74_RS04330	COG1451	nucleotide metabolic process
BZY74_RS04335	COG2949	membrane
BZY74_RS04340	COG0673	inositol 2-dehydrogenase activity
BZY74_RS04345	COG0861	Integral membrane protein TerC family
BZY74_RS04350	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BZY74_RS04360	COG2721	sulfolactate sulfo-lyase activity
BZY74_RS04370	COG2271	Major facilitator Superfamily
BZY74_RS04395	COG2186	Transcriptional regulator
BZY74_RS04400	COG0586	Pfam SNARE associated Golgi protein
BZY74_RS04410	COG1422	Protein of unknown function (DUF1090)
BZY74_RS04415	COG4575	ribosome binding
BZY74_RS04420	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BZY74_RS04430	COG2259	Doxx family
BZY74_RS04435	COG0435	Glutathione S-transferase
BZY74_RS04440	COG3152	Membrane
BZY74_RS04445	COG3152	Membrane
BZY74_RS04455	COG0583	DNA-binding transcription factor activity
BZY74_RS04460	COG1741	Belongs to the pirin family
BZY74_RS04475	COG0814	amino acid
BZY74_RS04480	COG1760	l-serine dehydratase
BZY74_RS04485	COG0251	oxidation-reduction process
BZY74_RS04490	COG1882	Formate acetyltransferase
BZY74_RS04495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BZY74_RS04505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZY74_RS04515	COG0583	DNA-binding transcription factor activity
BZY74_RS04540	COG3547	Transposase (IS116 IS110 IS902 family)
BZY74_RS04550	COG1929	Belongs to the glycerate kinase type-1 family
BZY74_RS04555	COG2084	Dehydrogenase
BZY74_RS04565	COG2271	Major facilitator Superfamily
BZY74_RS04570	COG2721	sulfolactate sulfo-lyase activity
BZY74_RS04575	COG2002	toxin-antitoxin pair type II binding
BZY74_RS04585	COG1349	DNA-binding transcription factor activity
BZY74_RS04600	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS04610	COG3716	PTS system mannose fructose sorbose family IID component
BZY74_RS04615	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS04620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BZY74_RS04625	COG2222	sugar isomerase
BZY74_RS04635	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS04640	COG3715	PTS system
BZY74_RS04645	COG3716	PTS system mannose fructose sorbose family IID component
BZY74_RS04650	COG0363	glucosamine-6-phosphate deaminase activity
BZY74_RS04655	COG3539	Fimbrial protein
BZY74_RS04660	COG3121	Chaperone
BZY74_RS04665	COG3188	usher protein
BZY74_RS04670	COG3539	Fimbrial protein
BZY74_RS04675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BZY74_RS04695	COG2823	Periplasmic or secreted lipoprotein
BZY74_RS04700	COG0701	Predicted permease
BZY74_RS04705	COG0702	epimerase
BZY74_RS04710	COG0693	protein deglycase activity
BZY74_RS04725	COG3153	acetyltransferase
BZY74_RS04730	COG3154	lipid carrier protein
BZY74_RS04735	COG0826	peptidase U32
BZY74_RS04740	COG0826	peptidase U32
BZY74_RS04745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BZY74_RS04750	COG0814	amino acid
BZY74_RS04755	COG0513	Belongs to the DEAD box helicase family
BZY74_RS04790	COG0195	Participates in both transcription termination and antitermination
BZY74_RS04820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZY74_RS04830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BZY74_RS04835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZY74_RS04845	COG1534	Rna-binding protein
BZY74_RS04850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZY74_RS04855	COG2027	D-alanyl-D-alanine carboxypeptidase
BZY74_RS04865	COG0697	spore germination
BZY74_RS04880	COG0142	geranyltranstransferase activity
BZY74_RS04885	COG3423	Transcriptional regulator
BZY74_RS04895	COG5007	Belongs to the BolA IbaG family
BZY74_RS04900	COG3113	response to antibiotic
BZY74_RS04905	COG2854	intermembrane phospholipid transfer
BZY74_RS04910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZY74_RS04915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BZY74_RS04920	COG1127	ABC transporter
BZY74_RS04925	COG0530	calcium, potassium:sodium antiporter activity
BZY74_RS04930	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BZY74_RS04930	COG0517	IMP dehydrogenase activity
BZY74_RS04935	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BZY74_RS04940	COG3117	lipopolysaccharide transmembrane transporter activity
BZY74_RS04945	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BZY74_RS04950	COG1137	ATPase activity
BZY74_RS04955	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BZY74_RS04960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BZY74_RS04975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS04980	COG0515	serine threonine protein kinase
BZY74_RS04990	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BZY74_RS04995	COG5002	protein histidine kinase activity
BZY74_RS04995	COG2198	Histidine kinase
BZY74_RS04995	COG0784	Response regulator, receiver
BZY74_RS05000	COG1242	4 iron, 4 sulfur cluster binding
BZY74_RS05015	COG0070	glutamate synthase
BZY74_RS05015	COG0069	glutamate synthase activity
BZY74_RS05015	COG0067	glutamate synthase
BZY74_RS05020	COG0493	'glutamate synthase
BZY74_RS05025	COG4804	nuclease activity
BZY74_RS05030	COG2731	YhcH YjgK YiaL family protein
BZY74_RS05065	COG3069	C4-dicarboxylate transmembrane transporter activity
BZY74_RS05070	COG2969	positive regulation of protein catabolic process
BZY74_RS05075	COG0625	glutathione transferase activity
BZY74_RS05105	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BZY74_RS05110	COG3105	Protein conserved in bacteria
BZY74_RS05115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZY74_RS05120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZY74_RS05140	COG2732	(Barnase) inhibitor
BZY74_RS05160	COG0583	DNA-binding transcription factor activity
BZY74_RS05165	COG0312	modulator of DNA gyrase
BZY74_RS05170	COG3164	Protein of unknown function
BZY74_RS05175	COG1530	ribonuclease E activity
BZY74_RS05185	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BZY74_RS05190	COG1792	Involved in formation and maintenance of cell shape
BZY74_RS05195	COG1077	Cell shape determining protein MreB Mrl
BZY74_RS05210	COG2199	diguanylate cyclase activity
BZY74_RS05210	COG2200	EAL domain
BZY74_RS05215	COG0604	alcohol dehydrogenase
BZY74_RS05225	COG0511	ligase activity, forming carbon-carbon bonds
BZY74_RS05230	COG0439	Biotin carboxylase
BZY74_RS05235	COG3924	membrane
BZY74_RS05240	COG4145	pantothenate transmembrane transporter activity
BZY74_RS05250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZY74_RS05260	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BZY74_RS05270	COG1309	transcriptional regulator
BZY74_RS05280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZY74_RS05285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZY74_RS05300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZY74_RS05305	COG4597	amino acid ABC transporter
BZY74_RS05310	COG0765	amino acid transport
BZY74_RS05315	COG1126	abc transporter atp-binding protein
BZY74_RS05355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BZY74_RS05375	COG0551	DNA topoisomerase type I activity
BZY74_RS05385	COG0758	DNA mediated transformation
BZY74_RS05405	COG0569	domain protein
BZY74_RS05415	COG3036	rescue of stalled ribosome
BZY74_RS05420	COG0789	Transcriptional regulator
BZY74_RS05460	COG0201	protein transport
BZY74_RS05550	COG0089	rRNA binding
BZY74_RS05630	COG2964	Protein conserved in bacteria
BZY74_RS05635	COG0545	Peptidyl-prolyl cis-trans isomerase
BZY74_RS05645	COG1047	Peptidyl-prolyl cis-trans
BZY74_RS05650	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BZY74_RS05670	COG0488	(ABC) transporter
BZY74_RS05675	COG0429	hydrolase of the alpha beta-hydrolase fold
BZY74_RS05685	COG3954	Phosphoribulokinase
BZY74_RS05690	COG1765	OsmC-like protein
BZY74_RS05700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZY74_RS05705	COG1289	transmembrane transporter activity
BZY74_RS05710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BZY74_RS05715	COG0512	Glutamine amidotransferase of anthranilate synthase
BZY74_RS05720	COG2184	nucleotidyltransferase activity
BZY74_RS05730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZY74_RS05740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BZY74_RS05745	COG2146	nitrite reductase [NAD(P)H] activity
BZY74_RS05750	COG2116	formate transmembrane transporter activity
BZY74_RS05765	COG0626	cystathionine gamma-synthase activity
BZY74_RS05780	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BZY74_RS05785	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BZY74_RS05790	COG3457	Alanine racemase
BZY74_RS05800	COG2188	Transcriptional regulator
BZY74_RS05805	COG0180	Tryptophanyl-tRNA synthetase
BZY74_RS05815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BZY74_RS05820	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BZY74_RS05825	COG3266	domain, Protein
BZY74_RS05840	COG4796	Type ii and iii secretion system protein
BZY74_RS05855	COG3166	PFAM Fimbrial assembly family protein
BZY74_RS05860	COG4972	Pilus assembly protein
BZY74_RS05865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BZY74_RS05870	COG0494	nUDIX hydrolase
BZY74_RS05880	COG1011	Hydrolase
BZY74_RS05885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BZY74_RS05895	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BZY74_RS05925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZY74_RS05930	COG2183	response to ionizing radiation
BZY74_RS05940	COG1918	ferrous iron import across plasma membrane
BZY74_RS05945	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BZY74_RS05960	COG5464	transposase or invertase
BZY74_RS05980	COG2610	gluconate transmembrane transporter activity
BZY74_RS05985	COG1640	4-alpha-glucanotransferase
BZY74_RS05990	COG0058	SHG alpha-glucan phosphorylase activity
BZY74_RS06005	COG1690	Belongs to the RtcB family
BZY74_RS06010	COG4650	regulator
BZY74_RS06015	COG1349	DNA-binding transcription factor activity
BZY74_RS06030	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZY74_RS06050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BZY74_RS06060	COG0058	SHG alpha-glucan phosphorylase activity
BZY74_RS06085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZY74_RS06090	COG2095	MarC family integral membrane protein
BZY74_RS06100	COG0514	ATP-dependent DNA helicase (RecQ)
BZY74_RS06105	COG2610	gluconate transmembrane transporter activity
BZY74_RS06110	COG3265	gluconokinase activity
BZY74_RS06115	COG1609	Transcriptional regulator
BZY74_RS06120	COG1741	Belongs to the pirin family
BZY74_RS06125	COG0673	inositol 2-dehydrogenase activity
BZY74_RS06135	COG1247	-acetyltransferase
BZY74_RS06140	COG3157	Type VI secretion system effector, Hcp
BZY74_RS06160	COG0405	Gamma-glutamyltransferase
BZY74_RS06170	COG0584	glycerophosphoryl diester phosphodiesterase
BZY74_RS06175	COG3842	ATPase activity
BZY74_RS06180	COG0395	ABC-type sugar transport system, permease component
BZY74_RS06185	COG1175	transmembrane transport
BZY74_RS06190	COG1653	transport
BZY74_RS06195	COG0410	ABC transporter
BZY74_RS06200	COG0411	ABC transporter
BZY74_RS06205	COG4177	L-phenylalanine transmembrane transporter activity
BZY74_RS06210	COG0559	Belongs to the binding-protein-dependent transport system permease family
BZY74_RS06215	COG0683	leucine binding
BZY74_RS06225	COG0456	acetyltransferase
BZY74_RS06230	COG0683	leucine binding
BZY74_RS06235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZY74_RS06240	COG2177	Part of the ABC transporter FtsEX involved in
BZY74_RS06245	COG2884	Cell division ATP-binding protein ftsE
BZY74_RS06250	COG0552	protein localization to endoplasmic reticulum
BZY74_RS06255	COG0742	ribosomal rna small subunit methyltransferase
BZY74_RS06260	COG3776	membrane
BZY74_RS06270	COG3714	YhhN family
BZY74_RS06285	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BZY74_RS06300	COG0628	permease
BZY74_RS06305	COG2091	lysine biosynthetic process via aminoadipic acid
BZY74_RS06310	COG0747	negative chemotaxis
BZY74_RS06315	COG0601	transmembrane transport
BZY74_RS06320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZY74_RS06325	COG0444	Belongs to the ABC transporter superfamily
BZY74_RS06350	COG0842	Transport permease protein
BZY74_RS06355	COG1129	ABC transporter
BZY74_RS06355	COG0842	Transport permease protein
BZY74_RS06360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZY74_RS06385	COG2081	HI0933 family
BZY74_RS06390	COG0306	phosphate transporter
BZY74_RS06400	COG0589	response to stress
BZY74_RS06410	COG3104	oligopeptide transport
BZY74_RS06420	COG0339	signal peptide processing
BZY74_RS06425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BZY74_RS06430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZY74_RS06445	COG0640	Transcriptional regulator
BZY74_RS06450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BZY74_RS06455	COG1393	Belongs to the ArsC family
BZY74_RS06475	COG3065	identical protein binding
BZY74_RS06485	COG2197	response regulator
BZY74_RS06490	COG1285	pathogenesis
BZY74_RS06505	COG3247	response to pH
BZY74_RS06510	COG2771	luxR family
BZY74_RS06520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZY74_RS06525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZY74_RS06535	COG2207	Transcriptional regulator
BZY74_RS06545	COG0076	glutamate decarboxylase activity
BZY74_RS06550	COG1858	cytochrome C peroxidase
BZY74_RS06560	COG2197	response regulator
BZY74_RS06565	COG0583	DNA-binding transcription factor activity
BZY74_RS06570	COG1295	ribonuclease BN
BZY74_RS06575	COG0477	Major facilitator Superfamily
BZY74_RS06580	COG2982	Protein involved in outer membrane biogenesis
BZY74_RS06585	COG2200	EAL domain
BZY74_RS06600	COG0612	Peptidase, M16
BZY74_RS06620	COG2199	diguanylate cyclase activity
BZY74_RS06620	COG2200	EAL domain
BZY74_RS06625	COG3118	belongs to the thioredoxin family
BZY74_RS06625	COG0457	Tetratricopeptide repeat
BZY74_RS06630	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BZY74_RS06635	COG1215	transferase activity, transferring glycosyl groups
BZY74_RS06640	COG1215	transferase activity, transferring glycosyl groups
BZY74_RS06665	COG2194	sulfuric ester hydrolase activity
BZY74_RS06700	COG0814	amino acid
BZY74_RS06705	COG4608	Belongs to the ABC transporter superfamily
BZY74_RS06710	COG0444	Belongs to the ABC transporter superfamily
BZY74_RS06715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZY74_RS06720	COG0601	transmembrane transport
BZY74_RS06725	COG0747	negative chemotaxis
BZY74_RS06745	COG2194	sulfuric ester hydrolase activity
BZY74_RS06750	COG2223	nitrite transmembrane transporter activity
BZY74_RS06760	COG5571	outer membrane autotransporter
BZY74_RS06765	COG2818	Glycosylase
BZY74_RS06770	COG0456	acetyltransferase
BZY74_RS06775	COG0243	molybdopterin cofactor binding
BZY74_RS06780	COG2885	chlorophyll binding
BZY74_RS06795	COG2944	sequence-specific DNA binding
BZY74_RS06800	COG1278	Cold shock
BZY74_RS06825	COG3274	enterobacterial common antigen metabolic process
BZY74_RS06830	COG4682	membrane
BZY74_RS06835	COG4682	membrane
BZY74_RS06840	COG1070	Carbohydrate kinase
BZY74_RS06850	COG4213	ABC transporter substrate-binding protein
BZY74_RS06855	COG1129	ABC transporter
BZY74_RS06860	COG4214	carbohydrate transport
BZY74_RS06865	COG1609	Transcriptional regulator
BZY74_RS06865	COG2207	Transcriptional regulator
BZY74_RS06870	COG2992	FlgJ-related protein
BZY74_RS06875	COG0366	Alpha amylase catalytic
BZY74_RS06880	COG3977	Valine--pyruvate aminotransferase
BZY74_RS06885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS06890	COG1414	Transcriptional regulator
BZY74_RS06900	COG2731	YhcH YjgK YiaL family protein
BZY74_RS06905	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BZY74_RS06910	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BZY74_RS06915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BZY74_RS06920	COG1070	Carbohydrate kinase
BZY74_RS06925	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BZY74_RS06930	COG3623	hexulose-6-phosphate isomerase
BZY74_RS06935	COG0235	Class ii aldolase
BZY74_RS06945	COG2211	Major facilitator Superfamily
BZY74_RS06955	COG3713	MltA-interacting MipA family protein
BZY74_RS06960	COG0583	DNA-binding transcription factor activity
BZY74_RS06965	COG1566	PFAM secretion protein HlyD family protein
BZY74_RS06980	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS06985	COG1454	alcohol dehydrogenase
BZY74_RS06990	COG3276	selenocysteine insertion sequence binding
BZY74_RS07000	COG0625	glutathione transferase activity
BZY74_RS07005	COG3209	COG3209 Rhs family protein
BZY74_RS07020	COG3209	COG3209 Rhs family protein
BZY74_RS07025	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BZY74_RS07050	COG1566	PFAM secretion protein HlyD family protein
BZY74_RS07060	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS07060	COG2213	PTS system mannitol-specific
BZY74_RS07070	COG3722	fumarate hydratase activity
BZY74_RS07100	COG1620	l-lactate permease
BZY74_RS07105	COG2186	Transcriptional regulator
BZY74_RS07115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BZY74_RS07120	COG1045	serine acetyltransferase
BZY74_RS07135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZY74_RS07140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BZY74_RS07155	COG4942	peptidase
BZY74_RS07160	COG2861	carbohydrate metabolic process
BZY74_RS07165	COG1216	Glycosyl transferase, family 2
BZY74_RS07175	COG0156	8-amino-7-oxononanoate synthase activity
BZY74_RS07190	COG0859	PFAM glycosyl transferase family 9
BZY74_RS07195	COG0859	PFAM glycosyl transferase family 9
BZY74_RS07215	COG3642	lipopolysaccharide core region biosynthetic process
BZY74_RS07225	COG0515	serine threonine protein kinase
BZY74_RS07230	COG0438	transferase activity, transferring glycosyl groups
BZY74_RS07235	COG0859	PFAM glycosyl transferase family 9
BZY74_RS07240	COG1519	Transferase
BZY74_RS07270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BZY74_RS07300	COG1561	YicC-like family, N-terminal region
BZY74_RS07305	COG3645	SOS response
BZY74_RS07310	COG2860	membrane
BZY74_RS07320	COG0194	GDP metabolic process
BZY74_RS07330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZY74_RS07335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZY74_RS07340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BZY74_RS07345	COG0786	glutamate:sodium symporter activity
BZY74_RS07350	COG2233	PERMEase
BZY74_RS07355	COG2982	Protein involved in outer membrane biogenesis
BZY74_RS07360	COG1501	Belongs to the glycosyl hydrolase 31 family
BZY74_RS07365	COG2211	Major facilitator Superfamily
BZY74_RS07380	COG2814	Major facilitator Superfamily
BZY74_RS07385	COG0697	spore germination
BZY74_RS07390	COG1464	Belongs to the NlpA lipoprotein family
BZY74_RS07420	COG2252	PERMEase
BZY74_RS07430	COG2271	Major facilitator Superfamily
BZY74_RS07435	COG2271	Major facilitator Superfamily
BZY74_RS07440	COG3851	Histidine kinase
BZY74_RS07445	COG2197	response regulator
BZY74_RS07450	COG0440	acetolactate synthase activity
BZY74_RS07455	COG0028	Belongs to the TPP enzyme family
BZY74_RS07490	COG2814	Major facilitator Superfamily
BZY74_RS07495	COG0641	radical SAM
BZY74_RS07505	COG2149	membrane
BZY74_RS07515	COG3119	arylsulfatase activity
BZY74_RS07520	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BZY74_RS07525	COG2207	Transcriptional regulator
BZY74_RS07545	COG2188	Transcriptional regulator
BZY74_RS07565	COG5645	(Lipo)protein
BZY74_RS07570	COG0823	Involved in the tonB-independent uptake of proteins
BZY74_RS07580	COG2271	Major facilitator Superfamily
BZY74_RS07590	COG0800	Aldolase
BZY74_RS07595	COG3734	2-keto-3-deoxy-galactonokinase
BZY74_RS07600	COG2186	Transcriptional regulator
BZY74_RS07610	COG0561	phosphatase activity
BZY74_RS07615	COG3753	Protein conserved in bacteria
BZY74_RS07620	COG0187	DNA topoisomerase II activity
BZY74_RS07630	COG0592	DNA-directed DNA polymerase activity
BZY74_RS07680	COG0814	amino acid
BZY74_RS07695	COG2091	lysine biosynthetic process via aminoadipic acid
BZY74_RS07700	COG0431	NADPH-dependent FMN reductase
BZY74_RS07705	COG2252	PERMEase
BZY74_RS07710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZY74_RS07720	COG3196	Protein conserved in bacteria
BZY74_RS07725	COG0363	glucosamine-6-phosphate deaminase activity
BZY74_RS07730	COG2382	esterase
BZY74_RS07740	COG2723	6-phospho-beta-galactosidase activity
BZY74_RS07745	COG2190	(PTS) system
BZY74_RS07745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS07745	COG1263	PTS System
BZY74_RS07750	COG3711	transcriptional antiterminator
BZY74_RS07755	COG0704	Plays a role in the regulation of phosphate uptake
BZY74_RS07760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BZY74_RS07765	COG0581	inorganic phosphate transmembrane transporter activity
BZY74_RS07770	COG0573	inorganic phosphate transmembrane transporter activity
BZY74_RS07775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BZY74_RS07785	COG3188	usher protein
BZY74_RS07800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BZY74_RS07855	COG3312	ion transport
BZY74_RS07870	COG0716	FMN binding
BZY74_RS07875	COG1522	sequence-specific DNA binding
BZY74_RS07905	COG1129	ABC transporter
BZY74_RS07910	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZY74_RS07915	COG1879	ABC-type sugar transport system periplasmic component
BZY74_RS07920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZY74_RS07925	COG1609	Transcriptional regulator
BZY74_RS07930	COG0477	Major facilitator Superfamily
BZY74_RS07935	COG2186	Transcriptional regulator
BZY74_RS07975	COG3085	chromosome segregation
BZY74_RS07980	COG0606	chelatase, subunit chli
BZY74_RS07995	COG3978	acetolactate synthase activity
BZY74_RS08000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZY74_RS08010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZY74_RS08015	COG0583	DNA-binding transcription factor activity
BZY74_RS08025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZY74_RS08030	COG3692	DNA binding
BZY74_RS08035	COG0210	DNA helicase
BZY74_RS08055	COG3118	belongs to the thioredoxin family
BZY74_RS08065	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BZY74_RS08075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BZY74_RS08080	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZY74_RS08085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BZY74_RS08090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BZY74_RS08095	COG1088	dTDP-glucose 4,6-dehydratase activity
BZY74_RS08100	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BZY74_RS08105	COG0456	acetyltransferase
BZY74_RS08110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BZY74_RS08115	COG2244	polysaccharide biosynthetic process
BZY74_RS08135	COG1113	amino acid transport
BZY74_RS08160	COG0641	radical SAM
BZY74_RS08165	COG3071	HemY protein
BZY74_RS08170	COG2959	enzyme of heme biosynthesis
BZY74_RS08175	COG1587	Uroporphyrinogen-III synthase
BZY74_RS08190	COG3072	Adenylate cyclase
BZY74_RS08205	COG5567	small periplasmic lipoprotein
BZY74_RS08215	COG3159	Protein conserved in bacteria
BZY74_RS08225	COG1011	Hydrolase
BZY74_RS08230	COG0210	DNA helicase
BZY74_RS08235	COG3698	Phosphodiester glycosidase
BZY74_RS08240	COG0598	Magnesium transport protein CorA
BZY74_RS08270	COG2962	Rard protein
BZY74_RS08275	COG2050	protein possibly involved in aromatic compounds catabolism
BZY74_RS08280	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BZY74_RS08285	COG0514	ATP-dependent DNA helicase (RecQ)
BZY74_RS08290	COG1280	lysine exporter protein (LysE YggA)
BZY74_RS08295	COG1280	lysine exporter protein (LysE YggA)
BZY74_RS08300	COG2267	carboxylic ester hydrolase activity
BZY74_RS08305	COG0561	phosphatase activity
BZY74_RS08310	COG0697	spore germination
BZY74_RS08315	COG0583	DNA-binding transcription factor activity
BZY74_RS08325	COG0412	Dienelactone hydrolase
BZY74_RS08330	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BZY74_RS08335	COG1322	Protein conserved in bacteria
BZY74_RS08345	COG3165	ubiquinone biosynthetic process from chorismate
BZY74_RS08355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZY74_RS08360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZY74_RS08365	COG0805	protein transport
BZY74_RS08375	COG0250	Participates in transcription elongation, termination and antitermination
BZY74_RS08380	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BZY74_RS08385	COG0543	2 iron, 2 sulfur cluster binding
BZY74_RS08405	COG1739	Uncharacterized protein family UPF0029
BZY74_RS08410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BZY74_RS08415	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BZY74_RS08445	COG1763	Mo-molybdopterin cofactor biosynthetic process
BZY74_RS08450	COG0746	molybdenum cofactor guanylyltransferase activity
BZY74_RS08455	COG3084	Protein conserved in bacteria
BZY74_RS08460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BZY74_RS08465	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZY74_RS08470	COG5339	Protein conserved in bacteria
BZY74_RS08475	COG0204	Acyl-transferase
BZY74_RS08485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZY74_RS08485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZY74_RS08505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZY74_RS08515	COG2204	response regulator
BZY74_RS08520	COG3852	Histidine kinase
BZY74_RS08530	COG0174	glutamine synthetase
BZY74_RS08540	COG1217	gtp-binding protein TYPA
BZY74_RS08545	COG2188	Transcriptional regulator
BZY74_RS08550	COG1082	Xylose isomerase domain protein TIM barrel
BZY74_RS08555	COG2271	Major facilitator Superfamily
BZY74_RS08560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZY74_RS08565	COG2211	Major facilitator Superfamily
BZY74_RS08570	COG2211	Major facilitator Superfamily
BZY74_RS08575	COG1501	Belongs to the glycosyl hydrolase 31 family
BZY74_RS08580	COG2017	converts alpha-aldose to the beta-anomer
BZY74_RS08585	COG2942	2-epimerase
BZY74_RS08590	COG3684	Belongs to the aldolase LacD family
BZY74_RS08595	COG2084	Dehydrogenase
BZY74_RS08600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZY74_RS08605	COG1349	DNA-binding transcription factor activity
BZY74_RS08610	COG1011	Hydrolase
BZY74_RS08625	COG0456	acetyltransferase
BZY74_RS08635	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BZY74_RS08650	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZY74_RS08655	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZY74_RS08665	COG2864	formate dehydrogenase
BZY74_RS08670	COG0437	4 iron, 4 sulfur cluster binding
BZY74_RS08695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS08695	COG3711	transcriptional antiterminator
BZY74_RS08700	COG1363	Peptidase, m42
BZY74_RS08705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS08705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS08710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS08750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZY74_RS08765	COG2258	MOSC domain
BZY74_RS08770	COG2205	protein histidine kinase activity
BZY74_RS08775	COG0745	RESPONSE REGULATOR receiver
BZY74_RS08780	COG3678	ATP-independent chaperone mediated protein folding
BZY74_RS08800	COG3547	Transposase (IS116 IS110 IS902 family)
BZY74_RS08805	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BZY74_RS08830	COG3152	Membrane
BZY74_RS08835	COG3691	Protein conserved in bacteria
BZY74_RS08840	COG0589	response to stress
BZY74_RS08850	COG1494	fructose-1,6-bisphosphatase
BZY74_RS08860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BZY74_RS08875	COG1575	Belongs to the MenA family. Type 1 subfamily
BZY74_RS08890	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZY74_RS08895	COG1609	Transcriptional regulator
BZY74_RS08900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BZY74_RS08910	COG3209	COG3209 Rhs family protein
BZY74_RS08940	COG0626	cystathionine gamma-synthase activity
BZY74_RS08945	COG0527	aspartate kinase activity
BZY74_RS08945	COG0460	homoserine dehydrogenase
BZY74_RS08950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BZY74_RS08960	COG0697	spore germination
BZY74_RS08965	COG3738	Protein conserved in bacteria
BZY74_RS08970	COG0371	Dehydrogenase
BZY74_RS08975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZY74_RS08980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS08980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZY74_RS08980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS08985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS08990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS08995	COG1882	Formate acetyltransferase
BZY74_RS09000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BZY74_RS09005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS09010	COG2207	Transcriptional regulator
BZY74_RS09015	COG2194	sulfuric ester hydrolase activity
BZY74_RS09030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BZY74_RS09045	COG0583	DNA-binding transcription factor activity
BZY74_RS09105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BZY74_RS09110	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BZY74_RS09110	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BZY74_RS09155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZY74_RS09160	COG0250	Participates in transcription elongation, termination and antitermination
BZY74_RS09205	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BZY74_RS09215	COG2104	thiamine diphosphate biosynthetic process
BZY74_RS09220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZY74_RS09255	COG3068	Protein conserved in bacteria
BZY74_RS09270	COG3678	ATP-independent chaperone mediated protein folding
BZY74_RS09280	COG4191	Histidine kinase
BZY74_RS09285	COG2204	response regulator
BZY74_RS09290	COG0151	Belongs to the GarS family
BZY74_RS09325	COG0456	acetyltransferase
BZY74_RS09335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BZY74_RS09340	COG2224	Isocitrate lyase
BZY74_RS09360	COG1414	Transcriptional regulator
BZY74_RS09365	COG1410	methionine synthase
BZY74_RS09365	COG0646	methionine synthase
BZY74_RS09370	COG1283	sodium-dependent phosphate transmembrane transporter activity
BZY74_RS09380	COG1187	pseudouridine synthase activity
BZY74_RS09395	COG3541	Predicted nucleotidyltransferase
BZY74_RS09400	COG0542	response to heat
BZY74_RS09405	COG0527	aspartate kinase activity
BZY74_RS09440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZY74_RS09455	COG2814	Major facilitator Superfamily
BZY74_RS09455	COG0477	Major facilitator Superfamily
BZY74_RS09460	COG3833	ABC-type maltose transport systems, permease component
BZY74_RS09465	COG1175	transmembrane transport
BZY74_RS09470	COG2182	Extracellular solute-binding protein
BZY74_RS09480	COG3842	ATPase activity
BZY74_RS09515	COG1357	PFAM Pentapeptide repeats (8 copies)
BZY74_RS09540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BZY74_RS09550	COG0534	Mate efflux family protein
BZY74_RS09555	COG3237	CsbD-like
BZY74_RS09560	COG0735	belongs to the Fur family
BZY74_RS09570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZY74_RS09580	COG0604	alcohol dehydrogenase
BZY74_RS09585	COG0305	Participates in initiation and elongation during chromosome replication
BZY74_RS09590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BZY74_RS09595	COG1448	Aminotransferase
BZY74_RS09605	COG3700	Belongs to the class B bacterial acid phosphatase family
BZY74_RS09610	COG0432	Pfam Uncharacterised protein family UPF0047
BZY74_RS09615	COG2315	Protein conserved in bacteria
BZY74_RS09620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BZY74_RS09625	COG0629	single-stranded DNA binding
BZY74_RS09640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BZY74_RS09645	COG2207	Transcriptional regulator
BZY74_RS09650	COG0789	Transcriptional regulator
BZY74_RS09670	COG2252	PERMEase
BZY74_RS09675	COG0025	NhaP-type Na H and K H
BZY74_RS09680	COG1357	PFAM Pentapeptide repeats (8 copies)
BZY74_RS09690	COG3162	membrane
BZY74_RS09695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BZY74_RS09710	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BZY74_RS09715	COG0437	4 iron, 4 sulfur cluster binding
BZY74_RS09720	COG3301	Polysulphide reductase, NrfD
BZY74_RS09725	COG1138	Cytochrome C-type biogenesis protein
BZY74_RS09730	COG3088	subunit of a heme lyase
BZY74_RS09735	COG4235	cytochrome complex assembly
BZY74_RS09745	COG1301	dicarboxylic acid transport
BZY74_RS09750	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BZY74_RS09765	COG1289	transmembrane transporter activity
BZY74_RS09770	COG1566	PFAM secretion protein HlyD family protein
BZY74_RS09780	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BZY74_RS09785	COG0698	ribose 5-phosphate isomerase
BZY74_RS09795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BZY74_RS09800	COG0456	acetyltransferase
BZY74_RS09805	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BZY74_RS09810	COG3454	Phosphonate metabolism
BZY74_RS09815	COG4778	phosphonate C-P lyase system protein PhnL
BZY74_RS09820	COG4107	phosphonate C-P lyase system protein PhnK
BZY74_RS09825	COG3627	carbon phosphorus lyase activity
BZY74_RS09830	COG3626	phosphonate metabolism
BZY74_RS09835	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BZY74_RS09840	COG3624	Phosphonate C-P lyase system protein PhnG
BZY74_RS09845	COG2188	Transcriptional regulator
BZY74_RS09850	COG3639	organic phosphonate transmembrane transporter activity
BZY74_RS09855	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BZY74_RS09865	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BZY74_RS09870	COG2824	Alkylphosphonate utilization operon protein PhnA
BZY74_RS09890	COG0477	Major facilitator Superfamily
BZY74_RS09900	COG0642	Histidine kinase
BZY74_RS09905	COG0745	RESPONSE REGULATOR receiver
BZY74_RS09910	COG2194	sulfuric ester hydrolase activity
BZY74_RS09915	COG0531	amino acid
BZY74_RS09920	COG2207	Transcriptional regulator
BZY74_RS09925	COG1982	Orn Lys Arg decarboxylase major
BZY74_RS09930	COG2169	Transcriptional regulator
BZY74_RS09940	COG1486	melibiose metabolic process
BZY74_RS09945	COG2211	Major facilitator Superfamily
BZY74_RS09950	COG3647	Membrane
BZY74_RS09955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BZY74_RS09955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BZY74_RS09960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZY74_RS09970	COG4565	transcriptional regulatory protein
BZY74_RS09975	COG3290	protein histidine kinase activity
BZY74_RS09980	COG3592	Divergent 4Fe-4S mono-cluster
BZY74_RS09985	COG2388	GCN5-related N-acetyl-transferase
BZY74_RS10005	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BZY74_RS10010	COG3104	oligopeptide transport
BZY74_RS10015	COG1982	Orn Lys Arg decarboxylase major
BZY74_RS10020	COG0531	amino acid
BZY74_RS10030	COG3710	Transcriptional regulator
BZY74_RS10045	COG1309	transcriptional regulator
BZY74_RS10060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZY74_RS10065	COG1027	Aspartate ammonia-lyase
BZY74_RS10070	COG3030	protein affecting phage T7 exclusion by the F plasmid
BZY74_RS10075	COG0531	amino acid
BZY74_RS10100	COG1509	lysine 2,3-aminomutase activity
BZY74_RS10110	COG5510	response to toxic substance
BZY74_RS10115	COG5510	response to toxic substance
BZY74_RS10120	COG2076	Multidrug Resistance protein
BZY74_RS10125	COG3040	lipid binding
BZY74_RS10130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BZY74_RS10145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BZY74_RS10150	COG1053	succinate dehydrogenase
BZY74_RS10175	COG3264	Mechanosensitive ion channel
BZY74_RS10175	COG1511	domain protein
BZY74_RS10215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BZY74_RS10220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BZY74_RS10220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BZY74_RS10225	COG0802	atpase or kinase
BZY74_RS10230	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZY74_RS10250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BZY74_RS10255	COG0330	HflC and HflK could
BZY74_RS10260	COG0330	HflC and HflK could
BZY74_RS10265	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BZY74_RS10280	COG0557	exoribonuclease II activity
BZY74_RS10285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZY74_RS10290	COG3789	protein conserved in bacteria
BZY74_RS10295	COG1842	Phage shock protein A
BZY74_RS10305	COG3766	membrane
BZY74_RS10310	COG5463	Belongs to the UPF0441 family
BZY74_RS10315	COG0754	glutathionylspermidine amidase activity
BZY74_RS10320	COG1960	acyl-CoA dehydrogenase activity
BZY74_RS10335	COG3650	response to hydrogen peroxide
BZY74_RS10340	COG1073	alpha beta
BZY74_RS10355	COG3037	sugar-specific permease SgaT UlaA
BZY74_RS10400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BZY74_RS10425	COG2271	Major facilitator Superfamily
BZY74_RS10430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BZY74_RS10435	COG4670	ketone body catabolic process
BZY74_RS10440	COG1024	Enoyl-CoA hydratase
BZY74_RS10455	COG1309	transcriptional regulator
BZY74_RS10460	COG3061	Opacity-associated protein A
BZY74_RS10470	COG0545	Peptidyl-prolyl cis-trans isomerase
BZY74_RS10475	COG1113	amino acid transport
BZY74_RS10485	COG0697	spore germination
BZY74_RS10490	COG0702	epimerase
BZY74_RS10495	COG1733	regulation of RNA biosynthetic process
BZY74_RS10500	COG0737	Belongs to the 5'-nucleotidase family
BZY74_RS10505	COG1218	3'(2'),5'-bisphosphate nucleotidase
BZY74_RS10510	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BZY74_RS10520	COG1253	flavin adenine dinucleotide binding
BZY74_RS10535	COG0729	surface antigen
BZY74_RS10540	COG2911	Protein conserved in bacteria
BZY74_RS10545	COG2105	PFAM AIG2 family protein
BZY74_RS10550	COG2336	PFAM SpoVT AbrB
BZY74_RS10555	COG2337	Toxic component of a toxin-antitoxin (TA) module
BZY74_RS10560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BZY74_RS10565	COG1879	ABC-type sugar transport system periplasmic component
BZY74_RS10570	COG1129	ABC transporter
BZY74_RS10575	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZY74_RS10580	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZY74_RS10590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BZY74_RS10600	COG0312	modulator of DNA gyrase
BZY74_RS10605	COG3783	Cytochrome b(562)
BZY74_RS10610	COG0602	queuosine metabolic process
BZY74_RS10615	COG1328	CTP reductase activity
BZY74_RS10620	COG0366	Alpha amylase catalytic
BZY74_RS10625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS10625	COG1263	PTS System
BZY74_RS10630	COG1609	Transcriptional regulator
BZY74_RS10635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BZY74_RS10640	COG0251	oxidation-reduction process
BZY74_RS10665	COG0251	oxidation-reduction process
BZY74_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS10675	COG1309	transcriptional regulator
BZY74_RS10680	COG2731	YhcH YjgK YiaL family protein
BZY74_RS10700	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BZY74_RS10705	COG0456	acetyltransferase
BZY74_RS10710	COG4269	membrane
BZY74_RS10715	COG0525	valine-tRNA ligase activity
BZY74_RS10720	COG2927	DNA polymerase III (CHI subunit)
BZY74_RS10730	COG0795	lipopolysaccharide-transporting ATPase activity
BZY74_RS10735	COG0795	lipopolysaccharide-transporting ATPase activity
BZY74_RS10740	COG0433	COG0433 Predicted ATPase
BZY74_RS10745	COG1064	alcohol dehydrogenase
BZY74_RS10780	COG1401	restriction endodeoxyribonuclease activity
BZY74_RS10805	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
BZY74_RS10810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZY74_RS10825	COG0582	viral genome integration into host DNA
BZY74_RS10830	COG4974	Belongs to the 'phage' integrase family
BZY74_RS10845	COG3539	Fimbrial protein
BZY74_RS10850	COG3121	Chaperone
BZY74_RS10855	COG3188	usher protein
BZY74_RS10860	COG3539	Fimbrial protein
BZY74_RS10865	COG3539	Fimbrial protein
BZY74_RS10870	COG3539	Fimbrial protein
BZY74_RS10875	COG2610	gluconate transmembrane transporter activity
BZY74_RS10890	COG0246	Mannitol dehydrogenase
BZY74_RS10900	COG2186	Transcriptional regulator
BZY74_RS10920	COG0583	DNA-binding transcription factor activity
BZY74_RS10925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BZY74_RS10930	COG0700	Nucleoside recognition
BZY74_RS10935	COG3366	ferrous iron transmembrane transporter activity
BZY74_RS10950	COG0477	Major facilitator Superfamily
BZY74_RS10965	COG1924	4 iron, 4 sulfur cluster binding
BZY74_RS10970	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BZY74_RS10975	COG2733	membrane
BZY74_RS10980	COG2814	Major facilitator Superfamily
BZY74_RS10990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZY74_RS10995	COG5457	Domain of unknown function (DUF1127)
BZY74_RS11005	COG0523	cobalamin synthesis protein
BZY74_RS11010	COG2879	small protein
BZY74_RS11015	COG1966	Carbon starvation protein
BZY74_RS11025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BZY74_RS11030	COG2368	4-hydroxyphenylacetate
BZY74_RS11050	COG3971	2-oxopent-4-enoate hydratase activity
BZY74_RS11060	COG3384	dioxygenase
BZY74_RS11065	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS11070	COG0179	Fumarylacetoacetate (FAA) hydrolase
BZY74_RS11075	COG1846	Transcriptional regulator
BZY74_RS11080	COG0840	transmembrane signaling receptor activity
BZY74_RS11085	COG2271	Major facilitator Superfamily
BZY74_RS11090	COG1802	Transcriptional regulator
BZY74_RS11095	COG1063	alcohol dehydrogenase
BZY74_RS11110	COG1484	DNA-dependent DNA replication
BZY74_RS11125	COG2966	Psort location CytoplasmicMembrane, score
BZY74_RS11130	COG2197	response regulator
BZY74_RS11135	COG2197	response regulator
BZY74_RS11140	COG4114	ferric iron reductase
BZY74_RS11170	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BZY74_RS11175	COG0456	acetyltransferase
BZY74_RS11180	COG1011	Hydrolase
BZY74_RS11190	COG2823	Periplasmic or secreted lipoprotein
BZY74_RS11200	COG4667	esterase of the alpha-beta hydrolase superfamily
BZY74_RS11205	COG0084	hydrolase, TatD family'
BZY74_RS11210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BZY74_RS11215	COG1328	CTP reductase activity
BZY74_RS11245	COG3726	membrane protein affecting hemolysin expression
BZY74_RS11250	COG0560	Phosphoserine phosphatase
BZY74_RS11255	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BZY74_RS11260	COG3172	ATPase kinase involved in NAD metabolism
BZY74_RS11260	COG1056	cytidyltransferase-related domain
BZY74_RS11265	COG0488	(ABC) transporter
BZY74_RS11275	COG0741	lytic transglycosylase activity
BZY74_RS11295	COG2207	Transcriptional regulator
BZY74_RS11295	COG3708	Transcriptional regulator
BZY74_RS11300	COG3045	CreA protein
BZY74_RS11305	COG0745	RESPONSE REGULATOR receiver
BZY74_RS11310	COG2205	protein histidine kinase activity
BZY74_RS11315	COG4452	Inner membrane protein CreD
BZY74_RS11320	COG0745	RESPONSE REGULATOR receiver
BZY74_RS11330	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BZY74_RS11340	COG0460	homoserine dehydrogenase
BZY74_RS11340	COG0527	aspartate kinase activity
BZY74_RS11350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BZY74_RS11365	COG1115	amino acid carrier protein
BZY74_RS11370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZY74_RS11375	COG0521	Mo-molybdopterin cofactor biosynthetic process
BZY74_RS11380	COG1584	GPR1 FUN34 yaaH family protein
BZY74_RS11385	COG4735	regulation of single-species biofilm formation
BZY74_RS11415	COG3119	arylsulfatase activity
BZY74_RS11425	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BZY74_RS11430	COG0583	DNA-binding transcription factor activity
BZY74_RS11460	COG0196	riboflavin kinase activity
BZY74_RS11475	COG1047	Peptidyl-prolyl cis-trans
BZY74_RS11500	COG0505	Belongs to the CarA family
BZY74_RS11505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BZY74_RS11560	COG0644	oxidoreductase
BZY74_RS11565	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BZY74_RS11570	COG2271	Major facilitator Superfamily
BZY74_RS11590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BZY74_RS11630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZY74_RS11635	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZY74_RS11640	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BZY74_RS11645	COG0564	pseudouridine synthase activity
BZY74_RS11655	COG0417	DNA replication proofreading
BZY74_RS11660	COG0235	Class ii aldolase
BZY74_RS11680	COG4977	sequence-specific DNA binding
BZY74_RS11685	COG0586	Pfam SNARE associated Golgi protein
BZY74_RS11695	COG1178	ABC-type Fe3 transport system permease component
BZY74_RS11700	COG4143	(ABC) transporter
BZY74_RS11705	COG4533	DNA binding
BZY74_RS11715	COG2814	Major facilitator Superfamily
BZY74_RS11730	COG0473	3-isopropylmalate dehydrogenase activity
BZY74_RS11745	COG0583	DNA-binding transcription factor activity
BZY74_RS11750	COG0028	Belongs to the TPP enzyme family
BZY74_RS11755	COG0440	acetolactate synthase activity
BZY74_RS11765	COG1609	Transcriptional regulator
BZY74_RS11785	COG3116	cell division
BZY74_RS11790	COG0768	penicillin binding
BZY74_RS11795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BZY74_RS11800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BZY74_RS11815	COG0772	Belongs to the SEDS family
BZY74_RS11830	COG1181	Belongs to the D-alanine--D-alanine ligase family
BZY74_RS11835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BZY74_RS11840	COG0849	cell division
BZY74_RS11845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BZY74_RS11865	COG0494	nUDIX hydrolase
BZY74_RS11880	COG0237	dephospho-CoA kinase activity
BZY74_RS11890	COG1459	type II secretion system
BZY74_RS11895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BZY74_RS11900	COG4969	Belongs to the N-Me-Phe pilin family
BZY74_RS11910	COG0157	Belongs to the NadC ModD family
BZY74_RS11915	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZY74_RS11920	COG3725	Membrane protein required for beta-lactamase induction
BZY74_RS11925	COG1113	amino acid transport
BZY74_RS11930	COG2186	Transcriptional regulator
BZY74_RS11940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BZY74_RS11945	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZY74_RS11950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZY74_RS11955	COG3064	Membrane
BZY74_RS11965	COG1049	propionate catabolic process, 2-methylcitrate cycle
BZY74_RS11990	COG2132	Multicopper oxidase
BZY74_RS11995	COG4993	Dehydrogenase
BZY74_RS12000	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BZY74_RS12005	COG0288	reversible hydration of carbon dioxide
BZY74_RS12010	COG1131	(ABC) transporter
BZY74_RS12015	COG0842	Transport permease protein
BZY74_RS12020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS12025	COG0726	polysaccharide deacetylase
BZY74_RS12045	COG5464	transposase or invertase
BZY74_RS12060	COG3539	Fimbrial protein
BZY74_RS12065	COG3539	Fimbrial protein
BZY74_RS12070	COG3539	Fimbrial protein
BZY74_RS12075	COG3539	Fimbrial protein
BZY74_RS12080	COG3188	usher protein
BZY74_RS12085	COG3121	Chaperone
BZY74_RS12090	COG3539	Fimbrial protein
BZY74_RS12095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BZY74_RS12100	COG0617	tRNA 3'-terminal CCA addition
BZY74_RS12110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BZY74_RS12120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BZY74_RS12125	COG1643	Atp-dependent helicase
BZY74_RS12135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BZY74_RS12140	COG4774	siderophore transport
BZY74_RS12145	COG1120	ATPase activity
BZY74_RS12150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZY74_RS12155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZY74_RS12175	COG2860	membrane
BZY74_RS12180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZY74_RS12200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZY74_RS12205	COG3835	regulator
BZY74_RS12225	COG0024	Methionine aminopeptidase
BZY74_RS12260	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BZY74_RS12265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BZY74_RS12270	COG0575	Belongs to the CDS family
BZY74_RS12275	COG0750	zinc metalloprotease
BZY74_RS12285	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BZY74_RS12290	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BZY74_RS12315	COG0587	DNA-directed DNA polymerase activity
BZY74_RS12325	COG1982	Orn Lys Arg decarboxylase major
BZY74_RS12330	COG0346	lactoylglutathione lyase activity
BZY74_RS12340	COG4568	rho-dependent transcription termination
BZY74_RS12350	COG4681	YaeQ
BZY74_RS12355	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BZY74_RS12360	COG3015	lipoprotein NlpE involved in copper resistance
BZY74_RS12370	COG3547	Transposase (IS116 IS110 IS902 family)
BZY74_RS12375	COG0791	NLP P60 protein
BZY74_RS12385	COG1720	tRNA m6t6A37 methyltransferase activity
BZY74_RS12395	COG1464	Belongs to the NlpA lipoprotein family
BZY74_RS12400	COG2011	ABC-type metal ion transport system permease component
BZY74_RS12405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BZY74_RS12410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BZY74_RS12445	COG0656	L-ascorbic acid biosynthetic process
BZY74_RS12450	COG0583	DNA-binding transcription factor activity
BZY74_RS12460	COG2226	methyltransferase
BZY74_RS12465	COG1388	LysM domain
BZY74_RS12465	COG0741	lytic transglycosylase activity
BZY74_RS12475	COG2226	methyltransferase
BZY74_RS12485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BZY74_RS12505	COG4104	PAAR repeat-containing protein
BZY74_RS12510	COG3157	Type VI secretion system effector, Hcp
BZY74_RS12605	COG3209	COG3209 Rhs family protein
BZY74_RS12625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZY74_RS12635	COG1960	acyl-CoA dehydrogenase activity
BZY74_RS12645	COG0121	glutamine amidotransferase
BZY74_RS12650	COG3034	peptidoglycan biosynthetic process
BZY74_RS12655	COG3041	Addiction module toxin RelE StbE family
BZY74_RS12660	COG3077	Addiction module antitoxin, RelB DinJ family
BZY74_RS12665	COG0791	NLP P60 protein
BZY74_RS12695	COG0454	-acetyltransferase
BZY74_RS12705	COG1690	Belongs to the RtcB family
BZY74_RS12710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BZY74_RS12715	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZY74_RS12735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BZY74_RS12755	COG0583	DNA-binding transcription factor activity
BZY74_RS12760	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BZY74_RS12765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BZY74_RS12770	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BZY74_RS12775	COG2080	2 iron, 2 sulfur cluster binding
BZY74_RS12785	COG3477	response to acidic pH
BZY74_RS12795	COG0727	PFAM Uncharacterised protein family (UPF0153)
BZY74_RS12800	COG3121	Chaperone
BZY74_RS12810	COG3188	usher protein
BZY74_RS12860	COG1388	LysM domain
BZY74_RS12865	COG2207	Transcriptional regulator
BZY74_RS12865	COG3708	Transcriptional regulator
BZY74_RS12870	COG3059	membrane
BZY74_RS12880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZY74_RS12885	COG2207	Transcriptional regulator
BZY74_RS12890	COG0247	lactate metabolic process
BZY74_RS12895	COG1139	Iron-sulfur cluster binding protein
BZY74_RS12900	COG1556	Lactate utilization protein
BZY74_RS12940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZY74_RS12950	COG2200	EAL domain
BZY74_RS12950	COG2771	luxR family
BZY74_RS12955	COG0583	DNA-binding transcription factor activity
BZY74_RS12970	COG0666	response to abiotic stimulus
BZY74_RS12980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZY74_RS12985	COG1304	FMN binding
BZY74_RS12990	COG0549	Belongs to the carbamate kinase family
BZY74_RS12995	COG0402	S-adenosylhomocysteine deaminase activity
BZY74_RS13005	COG1879	ABC-type sugar transport system periplasmic component
BZY74_RS13010	COG1129	ABC transporter
BZY74_RS13015	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZY74_RS13025	COG1064	alcohol dehydrogenase
BZY74_RS13040	COG1280	lysine exporter protein (LysE YggA)
BZY74_RS13050	COG3829	transcription factor binding
BZY74_RS13055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BZY74_RS13060	COG0372	Belongs to the citrate synthase family
BZY74_RS13065	COG2079	MmgE PrpD family protein
BZY74_RS13070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BZY74_RS13075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BZY74_RS13080	COG0402	S-adenosylhomocysteine deaminase activity
BZY74_RS13085	COG0583	DNA-binding transcription factor activity
BZY74_RS13090	COG0288	reversible hydration of carbon dioxide
BZY74_RS13100	COG2807	transmembrane transport
BZY74_RS13105	COG2223	nitrite transmembrane transporter activity
BZY74_RS13120	COG1609	Transcriptional regulator
BZY74_RS13125	COG1414	Transcriptional regulator
BZY74_RS13160	COG2814	Major facilitator Superfamily
BZY74_RS13165	COG3122	Protein conserved in bacteria
BZY74_RS13195	COG1215	transferase activity, transferring glycosyl groups
BZY74_RS13200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BZY74_RS13210	COG4521	taurine ABC transporter
BZY74_RS13215	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BZY74_RS13220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZY74_RS13225	COG2175	clavaminate synthase activity
BZY74_RS13230	COG0113	porphobilinogen synthase activity
BZY74_RS13240	COG3468	outer membrane autotransporter barrel domain protein
BZY74_RS13245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZY74_RS13250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BZY74_RS13260	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BZY74_RS13280	COG1181	Belongs to the D-alanine--D-alanine ligase family
BZY74_RS13295	COG1785	Belongs to the alkaline phosphatase family
BZY74_RS13305	COG3706	GGDEF domain
BZY74_RS13310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BZY74_RS13335	COG4126	flavin adenine dinucleotide binding
BZY74_RS13355	COG1940	carbohydrate kinase activity
BZY74_RS13360	COG2814	Major facilitator Superfamily
BZY74_RS13365	COG0419	ATPase involved in DNA repair
BZY74_RS13370	COG0420	3'-5' exonuclease activity
BZY74_RS13375	COG0745	RESPONSE REGULATOR receiver
BZY74_RS13380	COG5002	protein histidine kinase activity
BZY74_RS13385	COG1114	Component of the transport system for branched-chain amino acids
BZY74_RS13390	COG1113	amino acid transport
BZY74_RS13395	COG0366	Alpha amylase catalytic
BZY74_RS13415	COG1862	Preprotein translocase
BZY74_RS13420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZY74_RS13425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZY74_RS13430	COG1403	HNH endonuclease
BZY74_RS13435	COG3248	Nucleoside-binding outer membrane protein
BZY74_RS13440	COG4238	major outer membrane lipoprotein
BZY74_RS13450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZY74_RS13450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZY74_RS13465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BZY74_RS13470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BZY74_RS13475	COG0667	Aldo Keto reductase
BZY74_RS13485	COG0142	geranyltranstransferase activity
BZY74_RS13500	COG0693	protein deglycase activity
BZY74_RS13505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BZY74_RS13515	COG2814	Major facilitator Superfamily
BZY74_RS13540	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BZY74_RS13545	COG1845	cytochrome c oxidase, subunit III
BZY74_RS13550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BZY74_RS13555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BZY74_RS13560	COG2223	nitrite transmembrane transporter activity
BZY74_RS13565	COG3056	Lipoprotein
BZY74_RS13575	COG0271	Belongs to the BolA IbaG family
BZY74_RS13600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BZY74_RS13605	COG0776	regulation of translation
BZY74_RS13610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZY74_RS13615	COG1555	photosystem II stabilization
BZY74_RS13620	COG0824	Thioesterase
BZY74_RS13630	COG4533	DNA binding
BZY74_RS13640	COG1522	sequence-specific DNA binding
BZY74_RS13645	COG1132	(ABC) transporter
BZY74_RS13650	COG1132	(ABC) transporter
BZY74_RS13655	COG0347	Belongs to the P(II) protein family
BZY74_RS13660	COG0004	ammonium transporteR
BZY74_RS13665	COG1946	Acyl-CoA thioesterase
BZY74_RS13670	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BZY74_RS13675	COG3695	enzyme binding
BZY74_RS13685	COG5507	3-demethylubiquinone-9 3-methyltransferase
BZY74_RS13690	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BZY74_RS13700	COG0110	maltose O-acetyltransferase activity
BZY74_RS13715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZY74_RS13720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZY74_RS13725	COG1309	transcriptional regulator
BZY74_RS13735	COG1196	nuclear chromosome segregation
BZY74_RS13735	COG3264	Mechanosensitive ion channel
BZY74_RS13745	COG3923	Primosomal replication protein n
BZY74_RS13750	COG2832	Protein of unknown function (DUF454)
BZY74_RS13765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BZY74_RS13805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZY74_RS13810	COG4651	solute:proton antiporter activity
BZY74_RS13810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZY74_RS13815	COG2223	nitrite transmembrane transporter activity
BZY74_RS13825	COG0737	Belongs to the 5'-nucleotidase family
BZY74_RS13830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BZY74_RS13840	COG3735	TraB family
BZY74_RS13845	COG3093	addiction module antidote protein HigA
BZY74_RS13850	COG2217	Heavy metal translocating P-type atpase
BZY74_RS13855	COG2066	Belongs to the glutaminase family
BZY74_RS13860	COG0531	amino acid
BZY74_RS13870	COG0789	Transcriptional regulator
BZY74_RS13875	COG1585	Membrane protein implicated in regulation of membrane protease activity
BZY74_RS13880	COG0330	HflC and HflK could
BZY74_RS13885	COG4619	ABC transporter
BZY74_RS13890	COG0390	transport system, permease component
BZY74_RS13895	COG3118	belongs to the thioredoxin family
BZY74_RS13900	COG0300	oxidoreductase activity
BZY74_RS13905	COG2755	lipolytic protein G-D-S-L family
BZY74_RS13910	COG4181	ATPase activity
BZY74_RS13915	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BZY74_RS13920	COG3209	COG3209 Rhs family protein
BZY74_RS13950	COG0583	DNA-binding transcription factor activity
BZY74_RS13960	COG1414	Transcriptional regulator
BZY74_RS13965	COG3960	tartronate-semialdehyde synthase activity
BZY74_RS13970	COG3622	Belongs to the hyi family
BZY74_RS13975	COG2084	Dehydrogenase
BZY74_RS13980	COG1953	Uracil, thiamine, allantoin
BZY74_RS13990	COG2233	PERMEase
BZY74_RS13995	COG1929	Belongs to the glycerate kinase type-1 family
BZY74_RS14000	COG3257	ureidoglycine aminohydrolase activity
BZY74_RS14005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BZY74_RS14010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BZY74_RS14015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZY74_RS14020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZY74_RS14030	COG0549	Belongs to the carbamate kinase family
BZY74_RS14035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BZY74_RS14040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BZY74_RS14055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZY74_RS14065	COG1988	membrane-bound metal-dependent
BZY74_RS14070	COG2501	S4 domain
BZY74_RS14080	COG3539	Fimbrial protein
BZY74_RS14085	COG3121	Chaperone
BZY74_RS14090	COG3188	usher protein
BZY74_RS14095	COG3539	Fimbrial protein
BZY74_RS14100	COG3539	Fimbrial protein
BZY74_RS14105	COG2197	response regulator
BZY74_RS14115	COG0582	viral genome integration into host DNA
BZY74_RS14215	COG2076	Multidrug Resistance protein
BZY74_RS14220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BZY74_RS14285	COG3772	lysozyme
BZY74_RS14305	COG4220	transposase activity
BZY74_RS14325	COG1030	water channel activity
BZY74_RS14375	COG1196	nuclear chromosome segregation
BZY74_RS14410	COG5301	cellulose 1,4-beta-cellobiosidase activity
BZY74_RS14415	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BZY74_RS14420	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BZY74_RS14430	COG0500	methyltransferase
BZY74_RS14445	COG4571	Outer membrane protease
BZY74_RS14465	COG2207	Transcriptional regulator
BZY74_RS14480	COG4783	chaperone-mediated protein folding
BZY74_RS14485	COG1215	transferase activity, transferring glycosyl groups
BZY74_RS14490	COG5433	transposase activity
BZY74_RS14505	COG4104	PAAR repeat-containing protein
BZY74_RS14505	COG3209	COG3209 Rhs family protein
BZY74_RS14515	COG3209	COG3209 Rhs family protein
BZY74_RS14515	COG4104	PAAR repeat-containing protein
BZY74_RS14535	COG5002	protein histidine kinase activity
BZY74_RS14540	COG0745	RESPONSE REGULATOR receiver
BZY74_RS14550	COG1538	Outer membrane efflux protein
BZY74_RS14555	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZY74_RS14560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZY74_RS14565	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZY74_RS14570	COG1113	amino acid transport
BZY74_RS14575	COG0668	transmembrane transport
BZY74_RS14580	COG0778	Nitroreductase
BZY74_RS14585	COG2315	Protein conserved in bacteria
BZY74_RS14620	COG2977	Belongs to the P-Pant transferase superfamily
BZY74_RS14625	COG4771	TonB-dependent receptor
BZY74_RS14635	COG2382	esterase
BZY74_RS14640	COG3251	PFAM MbtH domain protein
BZY74_RS14645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZY74_RS14645	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BZY74_RS14650	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZY74_RS14655	COG1120	ATPase activity
BZY74_RS14660	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZY74_RS14665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZY74_RS14675	COG4592	Periplasmic binding protein
BZY74_RS14685	COG1169	isochorismate synthase
BZY74_RS14690	COG1021	2,3-dihydroxybenzoate-AMP ligase
BZY74_RS14695	COG3433	isochorismatase activity
BZY74_RS14695	COG1535	isochorismatase
BZY74_RS14700	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS14705	COG2050	protein possibly involved in aromatic compounds catabolism
BZY74_RS14710	COG1966	Carbon starvation protein
BZY74_RS14715	COG2879	small protein
BZY74_RS14720	COG0371	Dehydrogenase
BZY74_RS14725	COG0436	Aminotransferase
BZY74_RS14730	COG1475	DNA binding
BZY74_RS14735	COG3969	phosphoadenosine phosphosulfate
BZY74_RS14740	COG0583	DNA-binding transcription factor activity
BZY74_RS14745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZY74_RS14750	COG0450	alkyl hydroperoxide reductase
BZY74_RS14760	COG3634	alkyl hydroperoxide reductase activity
BZY74_RS14765	COG0589	response to stress
BZY74_RS14770	COG1063	alcohol dehydrogenase
BZY74_RS14780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZY74_RS14790	COG3719	Belongs to the RNase T2 family
BZY74_RS14795	COG0471	metal ion transport
BZY74_RS14810	COG3051	citrate lyase alpha subunit
BZY74_RS14815	COG2301	Belongs to the HpcH HpaI aldolase family
BZY74_RS14825	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BZY74_RS14830	COG3290	protein histidine kinase activity
BZY74_RS14835	COG4565	transcriptional regulatory protein
BZY74_RS14840	COG3069	C4-dicarboxylate transmembrane transporter activity
BZY74_RS14865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZY74_RS14870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZY74_RS14885	COG0583	DNA-binding transcription factor activity
BZY74_RS14905	COG1686	Belongs to the peptidase S11 family
BZY74_RS14910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZY74_RS14915	COG0772	Belongs to the SEDS family
BZY74_RS14920	COG0768	penicillin binding
BZY74_RS14930	COG0799	negative regulation of ribosome biogenesis
BZY74_RS14935	COG0406	alpha-ribazole phosphatase activity
BZY74_RS14945	COG1466	dna polymerase III delta subunit
BZY74_RS14960	COG2888	peptidyl-tyrosine sulfation
BZY74_RS14965	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BZY74_RS14975	COG2214	Heat shock protein DnaJ domain protein
BZY74_RS14980	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BZY74_RS14990	COG2214	Heat shock protein DnaJ domain protein
BZY74_RS14995	COG0443	Heat shock 70 kDa protein
BZY74_RS15005	COG1126	abc transporter atp-binding protein
BZY74_RS15010	COG0765	amino acid transport
BZY74_RS15015	COG0765	amino acid transport
BZY74_RS15020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZY74_RS15035	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BZY74_RS15040	COG4535	Mg2 and Co2 transporter CorC
BZY74_RS15050	COG1702	phosphate starvation-inducible protein PhoH
BZY74_RS15060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZY74_RS15105	COG0367	asparagine synthase
BZY74_RS15115	COG0647	UMP catabolic process
BZY74_RS15120	COG1940	carbohydrate kinase activity
BZY74_RS15120	COG1846	Transcriptional regulator
BZY74_RS15125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BZY74_RS15135	COG1263	PTS System
BZY74_RS15135	COG2190	(PTS) system
BZY74_RS15135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS15155	COG0735	belongs to the Fur family
BZY74_RS15165	COG0716	FMN binding
BZY74_RS15175	COG0596	Alpha beta hydrolase
BZY74_RS15180	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BZY74_RS15185	COG0033	Phosphoglucomutase
BZY74_RS15190	COG0531	amino acid
BZY74_RS15195	COG1982	Orn Lys Arg decarboxylase major
BZY74_RS15205	COG0745	RESPONSE REGULATOR receiver
BZY74_RS15210	COG2205	protein histidine kinase activity
BZY74_RS15240	COG3209	COG3209 Rhs family protein
BZY74_RS15270	COG3272	Protein of unknown function (DUF1722)
BZY74_RS15275	COG0415	Belongs to the DNA photolyase family
BZY74_RS15285	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BZY74_RS15290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BZY74_RS15295	COG1984	allophanate hydrolase subunit 2
BZY74_RS15310	COG3180	Ammonia monooxygenase
BZY74_RS15315	COG3539	Fimbrial protein
BZY74_RS15320	COG3121	Chaperone
BZY74_RS15325	COG3188	usher protein
BZY74_RS15330	COG3539	Fimbrial protein
BZY74_RS15335	COG0372	Belongs to the citrate synthase family
BZY74_RS15350	COG2009	succinate dehydrogenase
BZY74_RS15355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BZY74_RS15360	COG1053	succinate dehydrogenase
BZY74_RS15365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BZY74_RS15370	COG0567	Dehydrogenase, E1 component
BZY74_RS15375	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZY74_RS15385	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZY74_RS15390	COG2188	Transcriptional regulator
BZY74_RS15395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS15395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS15395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS15400	COG0383	alpha-mannosidase activity
BZY74_RS15410	COG1271	oxidase subunit
BZY74_RS15415	COG1294	oxidase, subunit
BZY74_RS15420	COG4890	Cyd operon protein YbgT
BZY74_RS15425	COG3790	cyd operon protein YbgE
BZY74_RS15430	COG0824	Thioesterase
BZY74_RS15435	COG0811	peptide transport
BZY74_RS15440	COG0848	biopolymer transport protein
BZY74_RS15445	COG3064	Membrane
BZY74_RS15455	COG2885	chlorophyll binding
BZY74_RS15460	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BZY74_RS15510	COG3201	nicotinamide mononucleotide transporter
BZY74_RS15515	COG1230	cation diffusion facilitator family transporter
BZY74_RS15530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZY74_RS15540	COG2017	converts alpha-aldose to the beta-anomer
BZY74_RS15550	COG1085	galactose-1-phosphate uridylyltransferase
BZY74_RS15555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BZY74_RS15560	COG1119	ATPase activity
BZY74_RS15565	COG2005	Transcriptional regulator
BZY74_RS15565	COG3585	molybdate ion transport
BZY74_RS15580	COG0725	ABC transporter, periplasmic molybdate-binding protein
BZY74_RS15585	COG4149	molybdate abc transporter
BZY74_RS15595	COG0561	phosphatase activity
BZY74_RS15605	COG0583	DNA-binding transcription factor activity
BZY74_RS15610	COG2828	Protein conserved in bacteria
BZY74_RS15615	COG0471	metal ion transport
BZY74_RS15620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BZY74_RS15625	COG4677	pectinesterase activity
BZY74_RS15635	COG1881	PFAM PEBP family protein
BZY74_RS15640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BZY74_RS15655	COG2226	methyltransferase
BZY74_RS15660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZY74_RS15670	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BZY74_RS15680	COG0521	Mo-molybdopterin cofactor biosynthetic process
BZY74_RS15690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BZY74_RS15695	COG0314	molybdopterin synthase activity
BZY74_RS15700	COG0670	Belongs to the BI1 family
BZY74_RS15710	COG0670	Belongs to the BI1 family
BZY74_RS15715	COG0392	lysyltransferase activity
BZY74_RS15720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BZY74_RS15725	COG3568	Endonuclease Exonuclease Phosphatase
BZY74_RS15735	COG0842	Transport permease protein
BZY74_RS15740	COG0842	Transport permease protein
BZY74_RS15745	COG1131	(ABC) transporter
BZY74_RS15755	COG1309	transcriptional regulator
BZY74_RS15760	COG0513	Belongs to the DEAD box helicase family
BZY74_RS15765	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
BZY74_RS15775	COG1199	ATP-dependent helicase activity
BZY74_RS15780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BZY74_RS15785	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BZY74_RS15795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BZY74_RS15805	COG4774	siderophore transport
BZY74_RS15820	COG0668	transmembrane transport
BZY74_RS15825	COG1126	abc transporter atp-binding protein
BZY74_RS15830	COG0765	amino acid transport
BZY74_RS15835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZY74_RS15860	COG5006	permease, DMT superfamily
BZY74_RS15865	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BZY74_RS15870	COG2194	sulfuric ester hydrolase activity
BZY74_RS15880	COG1321	iron dependent repressor
BZY74_RS15885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BZY74_RS15890	COG1376	ErfK ybiS ycfS ynhG family protein
BZY74_RS15895	COG0488	(ABC) transporter
BZY74_RS15905	COG3547	Transposase (IS116 IS110 IS902 family)
BZY74_RS15915	COG0561	phosphatase activity
BZY74_RS15920	COG1882	Formate acetyltransferase
BZY74_RS15925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BZY74_RS15930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZY74_RS15935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZY74_RS15940	COG0303	'Molybdopterin
BZY74_RS15945	COG1446	asparaginase
BZY74_RS15970	COG2200	EAL domain
BZY74_RS15975	COG2199	diguanylate cyclase activity
BZY74_RS15990	COG2133	pyrroloquinoline quinone binding
BZY74_RS15995	COG0625	glutathione transferase activity
BZY74_RS16000	COG1686	Belongs to the peptidase S11 family
BZY74_RS16005	COG1349	DNA-binding transcription factor activity
BZY74_RS16010	COG0671	phosphoesterase, PA-phosphatase related
BZY74_RS16015	COG2814	Major facilitator Superfamily
BZY74_RS16025	COG0561	phosphatase activity
BZY74_RS16030	COG0738	Major facilitator superfamily
BZY74_RS16035	COG3226	Transcriptional regulator
BZY74_RS16050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZY74_RS16060	COG0778	Nitroreductase
BZY74_RS16080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BZY74_RS16085	COG3842	ATPase activity
BZY74_RS16090	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZY74_RS16095	COG1177	transmembrane transport
BZY74_RS16110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZY74_RS16115	COG4160	amino acid transport
BZY74_RS16120	COG4215	(ABC) transporter
BZY74_RS16125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZY74_RS16130	COG1126	abc transporter atp-binding protein
BZY74_RS16145	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZY74_RS16150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZY74_RS16155	COG0702	epimerase
BZY74_RS16160	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BZY74_RS16165	COG0028	Belongs to the TPP enzyme family
BZY74_RS16170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZY74_RS16180	COG2431	L-lysine efflux transmembrane transporter activity
BZY74_RS16195	COG3593	DNA synthesis involved in DNA repair
BZY74_RS16200	COG2990	Protein conserved in bacteria
BZY74_RS16205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZY74_RS16210	COG1136	(ABC) transporter
BZY74_RS16210	COG0577	efflux transmembrane transporter activity
BZY74_RS16215	COG1278	Cold shock
BZY74_RS16225	COG0542	response to heat
BZY74_RS16250	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BZY74_RS16255	COG4988	ABC transporter
BZY74_RS16260	COG0492	ferredoxin-NADP+ reductase activity
BZY74_RS16270	COG1522	sequence-specific DNA binding
BZY74_RS16285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZY74_RS16295	COG0243	molybdopterin cofactor binding
BZY74_RS16300	COG0437	4 iron, 4 sulfur cluster binding
BZY74_RS16305	COG3302	dmso reductase anchor subunit
BZY74_RS16310	COG1335	isochorismatase
BZY74_RS16320	COG0531	amino acid
BZY74_RS16325	COG0583	DNA-binding transcription factor activity
BZY74_RS16330	COG2249	NAD(P)H dehydrogenase (quinone) activity
BZY74_RS16335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BZY74_RS16340	COG1882	Formate acetyltransferase
BZY74_RS16345	COG2116	formate transmembrane transporter activity
BZY74_RS16350	COG1944	ATP diphosphatase activity
BZY74_RS16355	COG2323	membrane
BZY74_RS16370	COG0501	Belongs to the peptidase M48B family
BZY74_RS16380	COG0539	negative regulation of cytoplasmic translation
BZY74_RS16390	COG2333	competence protein COMEC
BZY74_RS16390	COG0658	competence protein
BZY74_RS16395	COG1132	(ABC) transporter
BZY74_RS16405	COG3214	Protein conserved in bacteria
BZY74_RS16420	COG3173	Aminoglycoside phosphotransferase
BZY74_RS16425	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BZY74_RS16435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BZY74_RS16445	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BZY74_RS16455	COG2989	Protein conserved in bacteria
BZY74_RS16465	COG3108	Peptidase M15
BZY74_RS16470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZY74_RS16480	COG1448	Aminotransferase
BZY74_RS16500	COG0308	aminopeptidase N
BZY74_RS16510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZY74_RS16520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZY74_RS16525	COG0431	NADPH-dependent FMN reductase
BZY74_RS16530	COG3539	Fimbrial protein
BZY74_RS16535	COG3121	Chaperone
BZY74_RS16540	COG3188	usher protein
BZY74_RS16545	COG3539	Fimbrial protein
BZY74_RS16550	COG3539	Fimbrial protein
BZY74_RS16555	COG3539	Fimbrial protein
BZY74_RS16560	COG3121	Chaperone
BZY74_RS16575	COG0633	Ferredoxin
BZY74_RS16575	COG3217	Mosc domain protein beta barrel domain protein
BZY74_RS16585	COG0488	(ABC) transporter
BZY74_RS16590	COG2995	paraquat-inducible protein a
BZY74_RS16595	COG3008	intermembrane lipid transfer
BZY74_RS16595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZY74_RS16600	COG3009	Protein conserved in bacteria
BZY74_RS16605	COG3130	regulation of translation
BZY74_RS16615	COG1067	ATP-dependent peptidase activity
BZY74_RS16625	COG2885	chlorophyll binding
BZY74_RS16625	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BZY74_RS16640	COG3070	regulator of competence-specific genes
BZY74_RS16645	COG1289	transmembrane transporter activity
BZY74_RS16650	COG3304	Inner membrane component domain
BZY74_RS16655	COG0210	DNA helicase
BZY74_RS16670	COG1832	CoA-binding protein
BZY74_RS16685	COG1254	Belongs to the acylphosphatase family
BZY74_RS16690	COG2920	part of a sulfur-relay system
BZY74_RS16695	COG0670	Belongs to the BI1 family
BZY74_RS16705	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BZY74_RS16710	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BZY74_RS16715	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BZY74_RS16720	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BZY74_RS16725	COG1999	signal sequence binding
BZY74_RS16730	COG1773	rubredoxin
BZY74_RS16735	COG1271	oxidase subunit
BZY74_RS16740	COG1294	oxidase, subunit
BZY74_RS16755	COG3206	protein involved in exopolysaccharide biosynthesis
BZY74_RS16755	COG0489	protein tyrosine kinase activity
BZY74_RS16760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BZY74_RS16765	COG1596	polysaccharide export
BZY74_RS16770	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZY74_RS16790	COG1278	Cold shock
BZY74_RS16795	COG1278	Cold shock
BZY74_RS16815	COG0348	domain, Protein
BZY74_RS16820	COG0784	Response regulator, receiver
BZY74_RS16820	COG2205	protein histidine kinase activity
BZY74_RS16820	COG2198	Histidine kinase
BZY74_RS16825	COG1879	ABC-type sugar transport system periplasmic component
BZY74_RS16830	COG0745	RESPONSE REGULATOR receiver
BZY74_RS16835	COG3005	denitrification pathway
BZY74_RS16840	COG0243	molybdopterin cofactor binding
BZY74_RS16885	COG3729	General stress protein
BZY74_RS16890	COG2233	PERMEase
BZY74_RS16925	COG1309	transcriptional regulator
BZY74_RS16930	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZY74_RS16930	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZY74_RS16930	COG0506	proline dehydrogenase activity
BZY74_RS16945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BZY74_RS16965	COG2822	iron ion transport
BZY74_RS16970	COG2837	iron assimilation
BZY74_RS16980	COG1702	phosphate starvation-inducible protein PhoH
BZY74_RS16985	COG3658	cytochrome
BZY74_RS16990	COG1215	transferase activity, transferring glycosyl groups
BZY74_RS16995	COG0726	polysaccharide deacetylase
BZY74_RS16995	COG1649	PFAM Uncharacterised BCR, COG1649
BZY74_RS17000	COG0457	Tetratricopeptide repeat
BZY74_RS17005	COG3706	GGDEF domain
BZY74_RS17040	COG3381	protein complex oligomerization
BZY74_RS17050	COG1462	curli production assembly transport component CsgG
BZY74_RS17075	COG2197	response regulator
BZY74_RS17110	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BZY74_RS17115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BZY74_RS17140	COG2943	transferase activity, transferring hexosyl groups
BZY74_RS17145	COG5645	(Lipo)protein
BZY74_RS17160	COG1560	Kdo2-lipid A biosynthetic process
BZY74_RS17170	COG2353	YceI-like domain
BZY74_RS17175	COG3038	cytochrome b561
BZY74_RS17225	COG2999	glutathione oxidoreductase activity
BZY74_RS17235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZY74_RS17245	COG0673	inositol 2-dehydrogenase activity
BZY74_RS17250	COG0728	peptidoglycan biosynthetic process
BZY74_RS17255	COG3418	PFAM FlgN family protein
BZY74_RS17260	COG2747	anti-sigma28 factor FlgM
BZY74_RS17265	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BZY74_RS17270	COG1815	bacterial-type flagellum-dependent cell motility
BZY74_RS17275	COG1558	bacterial-type flagellum-dependent cell motility
BZY74_RS17280	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BZY74_RS17285	COG1749	Flagellar hook protein flgE
BZY74_RS17290	COG4787	bacterial-type flagellum-dependent cell motility
BZY74_RS17295	COG4786	Flagellar basal body rod
BZY74_RS17310	COG3951	Flagellar rod assembly protein muramidase FlgJ
BZY74_RS17310	COG1705	Flagellar rod assembly protein muramidase FlgJ
BZY74_RS17315	COG1256	bacterial-type flagellum assembly
BZY74_RS17320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BZY74_RS17325	COG1530	ribonuclease E activity
BZY74_RS17335	COG0564	pseudouridine synthase activity
BZY74_RS17340	COG0424	maF-like protein
BZY74_RS17345	COG1399	metal-binding, possibly nucleic acid-binding protein
BZY74_RS17365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BZY74_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS17380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZY74_RS17385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZY74_RS17390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BZY74_RS17400	COG0470	DNA polymerase III
BZY74_RS17405	COG0084	hydrolase, TatD family'
BZY74_RS17410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS17410	COG1263	PTS System
BZY74_RS17415	COG4773	Receptor
BZY74_RS17420	COG0537	adenosine 5'-monophosphoramidase activity
BZY74_RS17425	COG5633	Lipoprotein
BZY74_RS17430	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BZY74_RS17450	COG1252	NADH dehydrogenase
BZY74_RS17460	COG3134	Outer membrane lipoprotein
BZY74_RS17465	COG1309	transcriptional regulator
BZY74_RS17475	COG1388	LysM domain
BZY74_RS17475	COG1376	ErfK ybiS ycfS ynhG family protein
BZY74_RS17480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BZY74_RS17485	COG4763	Acyl-transferase
BZY74_RS17490	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZY74_RS17495	COG1136	(ABC) transporter
BZY74_RS17500	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZY74_RS17510	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BZY74_RS17515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BZY74_RS17525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BZY74_RS17530	COG1177	transmembrane transport
BZY74_RS17540	COG3842	ATPase activity
BZY74_RS17555	COG2850	peptidyl-arginine hydroxylation
BZY74_RS17560	COG2205	protein histidine kinase activity
BZY74_RS17570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BZY74_RS17590	COG1187	pseudouridine synthase activity
BZY74_RS17595	COG0538	isocitrate dehydrogenase activity
BZY74_RS17605	COG5562	phage envelope protein
BZY74_RS17610	COG0789	Transcriptional regulator
BZY74_RS17615	COG2200	EAL domain
BZY74_RS17640	COG2200	EAL domain
BZY74_RS17705	COG2894	cell division
BZY74_RS17735	COG0179	Fumarylacetoacetate (FAA) hydrolase
BZY74_RS17750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BZY74_RS17755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BZY74_RS17775	COG2719	SpoVR family
BZY74_RS17785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BZY74_RS17795	COG1619	proteins homologs of microcin C7 resistance protein MccF
BZY74_RS17810	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BZY74_RS17835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZY74_RS17835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS17835	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BZY74_RS17840	COG1461	Dihydroxyacetone kinase
BZY74_RS17845	COG2376	Dihydroxyacetone kinase
BZY74_RS17850	COG3284	Transcriptional regulator
BZY74_RS17855	COG3468	outer membrane autotransporter barrel domain protein
BZY74_RS17870	COG0012	GTP binding
BZY74_RS17885	COG0659	secondary active sulfate transmembrane transporter activity
BZY74_RS17890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZY74_RS17915	COG2890	protein-(glutamine-N5) methyltransferase activity
BZY74_RS17920	COG3094	Invasion gene expression up-regulator, SirB
BZY74_RS17925	COG2912	Transglutaminase-like superfamily
BZY74_RS17945	COG0387	Pfam Sodium calcium exchanger
BZY74_RS17950	COG4572	Cation transport regulator
BZY74_RS17955	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BZY74_RS17960	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BZY74_RS17965	COG4932	domain protein
BZY74_RS17970	COG2197	response regulator
BZY74_RS17975	COG3850	Histidine kinase
BZY74_RS17985	COG2223	nitrite transmembrane transporter activity
BZY74_RS17990	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BZY74_RS17995	COG1140	nitrate reductase beta subunit
BZY74_RS18000	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BZY74_RS18005	COG2181	nitrate reductase activity
BZY74_RS18025	COG0788	formyltetrahydrofolate deformylase activity
BZY74_RS18035	COG1752	Esterase of the alpha-beta hydrolase superfamily
BZY74_RS18040	COG0745	RESPONSE REGULATOR receiver
BZY74_RS18045	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZY74_RS18055	COG1435	thymidine kinase activity
BZY74_RS18060	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS18060	COG1454	alcohol dehydrogenase
BZY74_RS18065	COG2095	MarC family integral membrane protein
BZY74_RS18075	COG4166	transmembrane transport
BZY74_RS18080	COG0601	transmembrane transport
BZY74_RS18085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZY74_RS18090	COG0444	Belongs to the ABC transporter superfamily
BZY74_RS18095	COG4608	Belongs to the ABC transporter superfamily
BZY74_RS18115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZY74_RS18120	COG2350	Protein conserved in bacteria
BZY74_RS18125	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BZY74_RS18130	COG1607	acyl-coa hydrolase
BZY74_RS18150	COG3047	cAMP biosynthetic process
BZY74_RS18155	COG3685	Protein conserved in bacteria
BZY74_RS18160	COG3685	Protein conserved in bacteria
BZY74_RS18165	COG3729	General stress protein
BZY74_RS18180	COG0135	phosphoribosylanthranilate isomerase activity
BZY74_RS18180	COG0134	indole-3-glycerol-phosphate synthase activity
BZY74_RS18185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BZY74_RS18185	COG0512	Glutamine amidotransferase of anthranilate synthase
BZY74_RS18190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BZY74_RS18200	COG0613	PHP domain protein
BZY74_RS18205	COG0009	L-threonylcarbamoyladenylate synthase
BZY74_RS18210	COG1187	pseudouridine synthase activity
BZY74_RS18215	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BZY74_RS18220	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS18225	COG0616	signal peptide processing
BZY74_RS18240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZY74_RS18250	COG0583	DNA-binding transcription factor activity
BZY74_RS18270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BZY74_RS18280	COG0671	phosphoesterase, PA-phosphatase related
BZY74_RS18285	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BZY74_RS18290	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BZY74_RS18300	COG0023	Translation Initiation Factor
BZY74_RS18310	COG1349	DNA-binding transcription factor activity
BZY74_RS18320	COG5001	Diguanylate cyclase
BZY74_RS18335	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZY74_RS18335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZY74_RS18340	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BZY74_RS18345	COG2852	Protein conserved in bacteria
BZY74_RS18350	COG4172	Belongs to the ABC transporter superfamily
BZY74_RS18355	COG4172	Belongs to the ABC transporter superfamily
BZY74_RS18360	COG4171	peptide transport system, permease
BZY74_RS18365	COG4168	peptide transport system, permease
BZY74_RS18370	COG4166	transmembrane transport
BZY74_RS18385	COG0531	amino acid
BZY74_RS18390	COG0174	glutamine synthetase
BZY74_RS18395	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BZY74_RS18400	COG1396	sequence-specific DNA binding
BZY74_RS18400	COG1917	Cupin 2, conserved barrel domain protein
BZY74_RS18410	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS18415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BZY74_RS18420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BZY74_RS18425	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BZY74_RS18430	COG1842	Phage shock protein A
BZY74_RS18440	COG1983	PspC domain protein
BZY74_RS18450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BZY74_RS18455	COG0366	Alpha amylase catalytic
BZY74_RS18470	COG0366	Alpha amylase catalytic
BZY74_RS18475	COG1653	transport
BZY74_RS18480	COG1175	transmembrane transport
BZY74_RS18485	COG0395	ABC-type sugar transport system, permease component
BZY74_RS18490	COG1063	alcohol dehydrogenase
BZY74_RS18495	COG1082	Xylose isomerase domain protein TIM barrel
BZY74_RS18500	COG0673	inositol 2-dehydrogenase activity
BZY74_RS18505	COG1554	hydrolase, family 65, central catalytic
BZY74_RS18510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZY74_RS18515	COG3842	ATPase activity
BZY74_RS18525	COG1609	Transcriptional regulator
BZY74_RS18530	COG3106	COG3106 Predicted ATPase
BZY74_RS18540	COG3283	Transcriptional regulator of aromatic amino acids metabolism
BZY74_RS18545	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BZY74_RS18550	COG4948	Mandelate Racemase Muconate Lactonizing
BZY74_RS18555	COG2866	Carboxypeptidase
BZY74_RS18560	COG0702	epimerase
BZY74_RS18565	COG1073	alpha beta
BZY74_RS18570	COG1073	alpha beta
BZY74_RS18575	COG0583	DNA-binding transcription factor activity
BZY74_RS18580	COG4166	transmembrane transport
BZY74_RS18585	COG0668	transmembrane transport
BZY74_RS18590	COG3182	Iron-regulated membrane protein
BZY74_RS18595	COG0589	response to stress
BZY74_RS18600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZY74_RS18605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZY74_RS18610	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BZY74_RS18620	COG1473	amidohydrolase
BZY74_RS18625	COG1473	amidohydrolase
BZY74_RS18630	COG0583	DNA-binding transcription factor activity
BZY74_RS18635	COG2840	Smr protein MutS2
BZY74_RS18640	COG3706	GGDEF domain
BZY74_RS18655	COG0513	Belongs to the DEAD box helicase family
BZY74_RS18665	COG0589	response to stress
BZY74_RS18670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BZY74_RS18680	COG0674	pyruvate-flavodoxin oxidoreductase activity
BZY74_RS18680	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZY74_RS18680	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BZY74_RS18680	COG1013	pyruvate-flavodoxin oxidoreductase activity
BZY74_RS18685	COG3042	response to heat
BZY74_RS18690	COG3187	Heat shock protein
BZY74_RS18695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZY74_RS18700	COG2911	Protein conserved in bacteria
BZY74_RS18710	COG3784	Protein of unknown function (DUF1318)
BZY74_RS18715	COG2207	Transcriptional regulator
BZY74_RS18720	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS18725	COG3733	amine oxidase
BZY74_RS18730	COG2030	dehydratase
BZY74_RS18730	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS18735	COG3396	Phenylacetate-CoA oxygenase
BZY74_RS18740	COG3460	Phenylacetate-CoA oxygenase
BZY74_RS18745	COG3396	Phenylacetate-CoA oxygenase
BZY74_RS18750	COG2151	metal-sulfur cluster biosynthetic enzyme
BZY74_RS18755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZY74_RS18760	COG1024	Enoyl-CoA hydratase
BZY74_RS18765	COG1024	Enoyl-CoA hydratase
BZY74_RS18770	COG1250	3-hydroxyacyl-CoA dehydrogenase
BZY74_RS18775	COG2050	protein possibly involved in aromatic compounds catabolism
BZY74_RS18780	COG0183	Belongs to the thiolase family
BZY74_RS18785	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BZY74_RS18790	COG3327	negative regulation of DNA-templated transcription, initiation
BZY74_RS18795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BZY74_RS18800	COG0667	Aldo Keto reductase
BZY74_RS18810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BZY74_RS18815	COG4589	Belongs to the CDS family
BZY74_RS18820	COG2267	carboxylic ester hydrolase activity
BZY74_RS18825	COG2453	phosphatase
BZY74_RS18825	COG0671	phosphoesterase, PA-phosphatase related
BZY74_RS18835	COG1643	Atp-dependent helicase
BZY74_RS18840	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BZY74_RS18845	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS18850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BZY74_RS18855	COG3038	cytochrome b561
BZY74_RS18870	COG0840	transmembrane signaling receptor activity
BZY74_RS18875	COG0583	DNA-binding transcription factor activity
BZY74_RS18880	COG5383	Protein conserved in bacteria
BZY74_RS18900	COG2841	Protein conserved in bacteria
BZY74_RS18905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZY74_RS18910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BZY74_RS18915	COG1275	C4-dicarboxylate transporter malic acid transport protein
BZY74_RS18920	COG0500	methyltransferase
BZY74_RS18935	COG0675	Transposase, IS605 OrfB family
BZY74_RS18940	COG3135	benzoate transporter
BZY74_RS18945	COG1396	sequence-specific DNA binding
BZY74_RS18950	COG0826	peptidase U32
BZY74_RS18965	COG1598	PFAM Uncharacterised protein family UPF0150
BZY74_RS18970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZY74_RS18975	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BZY74_RS18980	COG3842	ATPase activity
BZY74_RS18985	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZY74_RS18990	COG1177	transmembrane transport
BZY74_RS19025	COG3238	Protein conserved in bacteria
BZY74_RS19030	COG1247	-acetyltransferase
BZY74_RS19040	COG2130	NADP-dependent
BZY74_RS19045	COG1802	Transcriptional regulator
BZY74_RS19050	COG4772	TonB-dependent receptor
BZY74_RS19065	COG3391	amine dehydrogenase activity
BZY74_RS19070	COG1113	amino acid transport
BZY74_RS19075	COG0625	glutathione transferase activity
BZY74_RS19090	COG3209	COG3209 Rhs family protein
BZY74_RS19125	COG3209	COG3209 Rhs family protein
BZY74_RS19145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BZY74_RS19150	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BZY74_RS19155	COG0384	phenazine biosynthesis protein PhzF
BZY74_RS19160	COG2181	nitrate reductase activity
BZY74_RS19165	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BZY74_RS19170	COG1140	nitrate reductase beta subunit
BZY74_RS19175	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BZY74_RS19180	COG2223	nitrite transmembrane transporter activity
BZY74_RS19185	COG4886	Leucine-rich repeat (LRR) protein
BZY74_RS19190	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BZY74_RS19195	COG0697	spore germination
BZY74_RS19200	COG0243	molybdopterin cofactor binding
BZY74_RS19200	COG3383	formate dehydrogenase (NAD+) activity
BZY74_RS19205	COG0243	molybdopterin cofactor binding
BZY74_RS19205	COG3383	formate dehydrogenase (NAD+) activity
BZY74_RS19210	COG0437	4 iron, 4 sulfur cluster binding
BZY74_RS19215	COG2864	formate dehydrogenase
BZY74_RS19220	COG3093	addiction module antidote protein HigA
BZY74_RS19225	COG1064	alcohol dehydrogenase
BZY74_RS19250	COG1764	response to oxidative stress
BZY74_RS19255	COG4608	Belongs to the ABC transporter superfamily
BZY74_RS19260	COG0444	Belongs to the ABC transporter superfamily
BZY74_RS19265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZY74_RS19270	COG0601	transmembrane transport
BZY74_RS19275	COG0747	negative chemotaxis
BZY74_RS19280	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BZY74_RS19285	COG2200	EAL domain
BZY74_RS19285	COG2202	Pas domain
BZY74_RS19285	COG2199	diguanylate cyclase activity
BZY74_RS19295	COG1649	PFAM Uncharacterised BCR, COG1649
BZY74_RS19300	COG0531	amino acid
BZY74_RS19305	COG0076	glutamate decarboxylase activity
BZY74_RS19315	COG0612	Peptidase, M16
BZY74_RS19320	COG4771	TonB-dependent receptor
BZY74_RS19325	COG4178	(ABC) transporter
BZY74_RS19330	COG0641	radical SAM
BZY74_RS19335	COG3119	arylsulfatase activity
BZY74_RS19350	COG0243	molybdopterin cofactor binding
BZY74_RS19355	COG3539	Fimbrial protein
BZY74_RS19360	COG3539	Fimbrial protein
BZY74_RS19365	COG3539	Fimbrial protein
BZY74_RS19370	COG3188	usher protein
BZY74_RS19380	COG3539	Fimbrial protein
BZY74_RS19395	COG3550	peptidyl-serine autophosphorylation
BZY74_RS19400	COG1396	sequence-specific DNA binding
BZY74_RS19405	COG2911	Protein conserved in bacteria
BZY74_RS19405	COG3210	domain, Protein
BZY74_RS19455	COG3781	membrane
BZY74_RS19475	COG2199	diguanylate cyclase activity
BZY74_RS19490	COG2066	Belongs to the glutaminase family
BZY74_RS19495	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS19500	COG0583	DNA-binding transcription factor activity
BZY74_RS19520	COG1846	Transcriptional regulator
BZY74_RS19525	COG4977	sequence-specific DNA binding
BZY74_RS19535	COG2723	6-phospho-beta-galactosidase activity
BZY74_RS19545	COG1447	Phosphotransferase system cellobiose-specific component IIA
BZY74_RS19550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZY74_RS19560	COG2188	Transcriptional regulator
BZY74_RS19565	COG0697	spore germination
BZY74_RS19570	COG2814	Major facilitator Superfamily
BZY74_RS19580	COG3706	GGDEF domain
BZY74_RS19585	COG3111	PFAM Bacterial OB fold (BOF) protein
BZY74_RS19590	COG1546	Belongs to the CinA family
BZY74_RS19600	COG0339	signal peptide processing
BZY74_RS19610	COG4221	oxidoreductase activity
BZY74_RS19615	COG1802	Transcriptional regulator
BZY74_RS19625	COG0246	Mannitol dehydrogenase
BZY74_RS19630	COG0477	Major facilitator Superfamily
BZY74_RS19635	COG1063	alcohol dehydrogenase
BZY74_RS19640	COG4948	Mandelate Racemase Muconate Lactonizing
BZY74_RS19660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZY74_RS19675	COG0243	molybdopterin cofactor binding
BZY74_RS19680	COG0243	molybdopterin cofactor binding
BZY74_RS19685	COG0437	4 iron, 4 sulfur cluster binding
BZY74_RS19690	COG3302	dmso reductase anchor subunit
BZY74_RS19695	COG3381	protein complex oligomerization
BZY74_RS19705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZY74_RS19710	COG1940	carbohydrate kinase activity
BZY74_RS19715	COG0583	DNA-binding transcription factor activity
BZY74_RS19720	COG2814	Major facilitator Superfamily
BZY74_RS19740	COG3591	Belongs to the peptidase S1B family
BZY74_RS19760	COG0628	permease
BZY74_RS19765	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BZY74_RS19770	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BZY74_RS19785	COG0531	amino acid
BZY74_RS19795	COG3136	membrane protein required for alginate biosynthesis
BZY74_RS19800	COG0745	RESPONSE REGULATOR receiver
BZY74_RS19805	COG2205	protein histidine kinase activity
BZY74_RS19815	COG0114	fumarate hydratase activity
BZY74_RS19820	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BZY74_RS19820	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BZY74_RS19825	COG1482	cell wall glycoprotein biosynthetic process
BZY74_RS19830	COG5339	Protein conserved in bacteria
BZY74_RS19845	COG3250	beta-galactosidase activity
BZY74_RS19850	COG1309	transcriptional regulator
BZY74_RS19855	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS19860	COG1609	Transcriptional regulator
BZY74_RS19865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS19865	COG1263	PTS System
BZY74_RS19870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BZY74_RS19880	COG0673	inositol 2-dehydrogenase activity
BZY74_RS19925	COG4659	FMN binding
BZY74_RS19935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BZY74_RS19945	COG3104	oligopeptide transport
BZY74_RS19950	COG0625	glutathione transferase activity
BZY74_RS19955	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BZY74_RS19970	COG3895	Periplasmic Protein
BZY74_RS19980	COG3133	Outer membrane lipoprotein
BZY74_RS19995	COG1566	PFAM secretion protein HlyD family protein
BZY74_RS20000	COG1289	transmembrane transporter activity
BZY74_RS20005	COG2032	superoxide dismutase activity
BZY74_RS20010	COG4989	oxidoreductase activity
BZY74_RS20015	COG3313	Fe-S protein
BZY74_RS20020	COG1309	transcriptional regulator
BZY74_RS20025	COG1902	pentaerythritol trinitrate reductase activity
BZY74_RS20030	COG0346	lactoylglutathione lyase activity
BZY74_RS20040	COG1201	RNA secondary structure unwinding
BZY74_RS20045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BZY74_RS20050	COG0791	NLP P60 protein
BZY74_RS20055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZY74_RS20060	COG2814	Major facilitator Superfamily
BZY74_RS20080	COG0583	DNA-binding transcription factor activity
BZY74_RS20085	COG2814	Major facilitator Superfamily
BZY74_RS20090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BZY74_RS20095	COG0307	riboflavin synthase, alpha
BZY74_RS20105	COG3468	outer membrane autotransporter barrel domain protein
BZY74_RS20125	COG4529	Protein conserved in bacteria
BZY74_RS20135	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BZY74_RS20140	COG0437	4 iron, 4 sulfur cluster binding
BZY74_RS20150	COG2414	aldehyde ferredoxin oxidoreductase
BZY74_RS20155	COG0437	4 iron, 4 sulfur cluster binding
BZY74_RS20165	COG0469	pyruvate kinase activity
BZY74_RS20170	COG4238	major outer membrane lipoprotein
BZY74_RS20175	COG1376	ErfK ybiS ycfS ynhG family protein
BZY74_RS20190	COG0719	Fe-S assembly protein
BZY74_RS20195	COG0396	ATPase activity
BZY74_RS20200	COG0719	Fe-S assembly protein
BZY74_RS20205	COG0316	Belongs to the HesB IscA family
BZY74_RS20215	COG2050	protein possibly involved in aromatic compounds catabolism
BZY74_RS20220	COG0247	lactate metabolic process
BZY74_RS20220	COG0277	FAD linked oxidase domain protein
BZY74_RS20230	COG0628	permease
BZY74_RS20245	COG0738	Major facilitator superfamily
BZY74_RS20250	COG2271	Major facilitator Superfamily
BZY74_RS20265	COG4670	ketone body catabolic process
BZY74_RS20270	COG1960	acyl-CoA dehydrogenase activity
BZY74_RS20275	COG1917	Cupin 2, conserved barrel domain protein
BZY74_RS20275	COG2207	Transcriptional regulator
BZY74_RS20285	COG2086	electron transfer activity
BZY74_RS20290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BZY74_RS20295	COG0644	oxidoreductase
BZY74_RS20300	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BZY74_RS20305	COG0318	PFAM AMP-dependent synthetase and ligase
BZY74_RS20310	COG0574	Belongs to the PEP-utilizing enzyme family
BZY74_RS20310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZY74_RS20325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZY74_RS20330	COG4256	Hemin uptake protein
BZY74_RS20340	COG2200	EAL domain
BZY74_RS20345	COG0791	NLP P60 protein
BZY74_RS20355	COG0386	Belongs to the glutathione peroxidase family
BZY74_RS20410	COG3137	Salt-induced outer membrane protein
BZY74_RS20415	COG1105	Belongs to the carbohydrate kinase PfkB family
BZY74_RS20425	COG3001	Fructosamine kinase
BZY74_RS20435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZY74_RS20440	COG1988	membrane-bound metal-dependent
BZY74_RS20445	COG1823	symporter activity
BZY74_RS20465	COG0753	catalase activity
BZY74_RS20475	COG1486	melibiose metabolic process
BZY74_RS20480	COG1917	Cupin 2, conserved barrel domain protein
BZY74_RS20480	COG2169	Transcriptional regulator
BZY74_RS20485	COG1447	Phosphotransferase system cellobiose-specific component IIA
BZY74_RS20490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZY74_RS20495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZY74_RS20505	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZY74_RS20515	COG0322	excinuclease ABC activity
BZY74_RS20525	COG3678	ATP-independent chaperone mediated protein folding
BZY74_RS20560	COG0708	Exodeoxyribonuclease III
BZY74_RS20565	COG0398	Pfam SNARE associated Golgi protein
BZY74_RS20575	COG0398	Pfam SNARE associated Golgi protein
BZY74_RS20580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZY74_RS20585	COG4134	Bacterial extracellular solute-binding protein
BZY74_RS20590	COG4135	transport system, permease component
BZY74_RS20595	COG4136	ATPase activity
BZY74_RS20600	COG2897	thiosulfate sulfurtransferase activity
BZY74_RS20605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BZY74_RS20610	COG0494	nUDIX hydrolase
BZY74_RS20620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BZY74_RS20630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZY74_RS20635	COG0709	Synthesizes selenophosphate from selenide and ATP
BZY74_RS20645	COG0778	Nitroreductase
BZY74_RS20655	COG0616	signal peptide processing
BZY74_RS20660	COG0252	asparaginase activity
BZY74_RS20665	COG1335	isochorismatase
BZY74_RS20670	COG2814	Major facilitator Superfamily
BZY74_RS20675	COG1349	DNA-binding transcription factor activity
BZY74_RS20680	COG0667	Aldo Keto reductase
BZY74_RS20685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZY74_RS20690	COG0191	fructose-bisphosphate aldolase activity
BZY74_RS20695	COG1063	alcohol dehydrogenase
BZY74_RS20700	COG2271	Major facilitator Superfamily
BZY74_RS20705	COG1063	alcohol dehydrogenase
BZY74_RS20710	COG3139	Protein of unknown function (DUF1315)
BZY74_RS20720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BZY74_RS20725	COG0676	glucose-6-phosphate 1-epimerase activity
BZY74_RS20730	COG0656	L-ascorbic acid biosynthetic process
BZY74_RS20735	COG3713	MltA-interacting MipA family protein
BZY74_RS20740	COG2766	serine protein kinase
BZY74_RS20750	COG2199	diguanylate cyclase activity
BZY74_RS20755	COG2199	diguanylate cyclase activity
BZY74_RS20760	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BZY74_RS20775	COG2207	Transcriptional regulator
BZY74_RS20780	COG2807	transmembrane transport
BZY74_RS20785	COG3189	MarR family transcriptional regulator
BZY74_RS20790	COG3042	response to heat
BZY74_RS20795	COG2199	diguanylate cyclase activity
BZY74_RS20795	COG2203	Gaf domain
BZY74_RS20810	COG2261	transglycosylase associated protein
BZY74_RS20815	COG0675	Transposase, IS605 OrfB family
BZY74_RS20830	COG3615	Tellurite resistance protein tehB
BZY74_RS20840	COG0583	DNA-binding transcription factor activity
BZY74_RS20845	COG0473	3-isopropylmalate dehydrogenase activity
BZY74_RS20850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZY74_RS20855	COG4638	Rieske (2fe-2S)
BZY74_RS20860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZY74_RS20865	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BZY74_RS20870	COG0318	PFAM AMP-dependent synthetase and ligase
BZY74_RS20875	COG3065	identical protein binding
BZY74_RS20880	COG1214	PFAM Peptidase M22, glycoprotease
BZY74_RS20885	COG1199	ATP-dependent helicase activity
BZY74_RS20890	COG0251	oxidation-reduction process
BZY74_RS20905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BZY74_RS20915	COG1760	l-serine dehydratase
BZY74_RS20920	COG2200	EAL domain
BZY74_RS20925	COG1253	flavin adenine dinucleotide binding
BZY74_RS20940	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZY74_RS20940	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS20945	COG3715	PTS system
BZY74_RS20950	COG3716	PTS system mannose fructose sorbose family IID component
BZY74_RS20970	COG2226	methyltransferase
BZY74_RS21005	COG1414	Transcriptional regulator
BZY74_RS21010	COG2814	Major facilitator Superfamily
BZY74_RS21020	COG0793	Belongs to the peptidase S41A family
BZY74_RS21030	COG1956	GAF domain-containing protein
BZY74_RS21035	COG2995	paraquat-inducible protein a
BZY74_RS21040	COG3008	intermembrane lipid transfer
BZY74_RS21060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BZY74_RS21070	COG1276	copper resistance
BZY74_RS21075	COG2372	response to copper ion
BZY74_RS21085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZY74_RS21090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BZY74_RS21095	COG1770	oligopeptidase
BZY74_RS21105	COG2979	Protein of unknown function (DUF533)
BZY74_RS21115	COG3141	response to X-ray
BZY74_RS21125	COG0800	Aldolase
BZY74_RS21130	COG0129	dihydroxy-acid dehydratase activity
BZY74_RS21135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BZY74_RS21140	COG1737	Transcriptional regulator
BZY74_RS21145	COG0469	pyruvate kinase activity
BZY74_RS21150	COG1560	Kdo2-lipid A biosynthetic process
BZY74_RS21155	COG0739	heme binding
BZY74_RS21160	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BZY74_RS21170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZY74_RS21200	COG0217	transcriptional regulatory protein
BZY74_RS21205	COG0494	nUDIX hydrolase
BZY74_RS21215	COG1335	isochorismatase
BZY74_RS21225	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BZY74_RS21240	COG0243	molybdopterin cofactor binding
BZY74_RS21245	COG3005	denitrification pathway
BZY74_RS21255	COG3102	Protein conserved in bacteria
BZY74_RS21270	COG3755	Protein conserved in bacteria
BZY74_RS21280	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZY74_RS21285	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZY74_RS21290	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BZY74_RS21295	COG0745	RESPONSE REGULATOR receiver
BZY74_RS21300	COG2201	protein-glutamate methylesterase activity
BZY74_RS21305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BZY74_RS21310	COG0840	transmembrane signaling receptor activity
BZY74_RS21315	COG0840	transmembrane signaling receptor activity
BZY74_RS21320	COG0835	chemotaxis
BZY74_RS21325	COG2198	Histidine kinase
BZY74_RS21325	COG0643	Histidine kinase
BZY74_RS21330	COG1360	Flagellar Motor Protein
BZY74_RS21335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BZY74_RS21350	COG0589	response to stress
BZY74_RS21360	COG1877	trehalose-phosphatase activity
BZY74_RS21365	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZY74_RS21370	COG1129	ABC transporter
BZY74_RS21375	COG1879	ABC-type sugar transport system periplasmic component
BZY74_RS21385	COG1528	Iron-storage protein
BZY74_RS21405	COG1528	Iron-storage protein
BZY74_RS21415	COG0814	amino acid
BZY74_RS21420	COG3012	SEC-C Motif Domain Protein
BZY74_RS21420	COG3318	Belongs to the UPF0149 family
BZY74_RS21450	COG2197	response regulator
BZY74_RS21460	COG2197	response regulator
BZY74_RS21465	COG1126	abc transporter atp-binding protein
BZY74_RS21470	COG0765	amino acid transport
BZY74_RS21480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZY74_RS21490	COG1191	sigma factor activity
BZY74_RS21505	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BZY74_RS21510	COG1516	flagellar protein fliS
BZY74_RS21520	COG0366	Alpha amylase catalytic
BZY74_RS21535	COG2391	methyltransferase activity
BZY74_RS21540	COG0425	Belongs to the sulfur carrier protein TusA family
BZY74_RS21545	COG2135	peptidase activity
BZY74_RS21560	COG1766	The M ring may be actively involved in energy transduction
BZY74_RS21565	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BZY74_RS21570	COG1317	bacterial-type flagellum organization
BZY74_RS21575	COG1157	protein secretion by the type III secretion system
BZY74_RS21580	COG2882	bacterial-type flagellum organization
BZY74_RS21585	COG3144	bacterial-type flagellum assembly
BZY74_RS21590	COG1580	Controls the rotational direction of flagella during chemotaxis
BZY74_RS21595	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BZY74_RS21600	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BZY74_RS21605	COG3190	flagellar
BZY74_RS21610	COG1338	Plays a role in the flagellum-specific transport system
BZY74_RS21615	COG1987	bacterial-type flagellum assembly
BZY74_RS21620	COG1684	flagellar biosynthetic protein fliR
BZY74_RS21625	COG2197	response regulator
BZY74_RS21660	COG5475	Uncharacterized small protein (DUF2158)
BZY74_RS21665	COG2354	Protein conserved in bacteria
BZY74_RS21670	COG0697	spore germination
BZY74_RS21675	COG3727	T/G mismatch-specific endonuclease activity
BZY74_RS21680	COG0270	DNA (cytosine-5-)-methyltransferase activity
BZY74_RS21685	COG1418	mRNA catabolic process
BZY74_RS21695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BZY74_RS21710	COG2205	protein histidine kinase activity
BZY74_RS21715	COG0745	RESPONSE REGULATOR receiver
BZY74_RS21720	COG2351	hydroxyisourate hydrolase activity
BZY74_RS21735	COG3443	Belongs to the bacterial solute-binding protein 9 family
BZY74_RS21740	COG3038	cytochrome b561
BZY74_RS21770	COG1388	LysM domain
BZY74_RS21770	COG1470	cell adhesion involved in biofilm formation
BZY74_RS21780	COG0477	Major facilitator Superfamily
BZY74_RS21785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BZY74_RS21790	COG0217	transcriptional regulatory protein
BZY74_RS21805	COG0534	Mate efflux family protein
BZY74_RS21815	COG0583	DNA-binding transcription factor activity
BZY74_RS21820	COG0583	DNA-binding transcription factor activity
BZY74_RS21830	COG1376	ErfK ybiS ycfS ynhG family protein
BZY74_RS21845	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BZY74_RS21905	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BZY74_RS21920	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BZY74_RS21935	COG1012	belongs to the aldehyde dehydrogenase family
BZY74_RS21935	COG1454	alcohol dehydrogenase
BZY74_RS21940	COG4656	Part of a membrane complex involved in electron transport
BZY74_RS21965	COG1289	transmembrane transporter activity
BZY74_RS21975	COG1686	Belongs to the peptidase S11 family
BZY74_RS21980	COG2925	Exonuclease
BZY74_RS21985	COG0425	Belongs to the sulfur carrier protein TusA family
BZY74_RS21990	COG2391	methyltransferase activity
BZY74_RS21995	COG0531	amino acid
BZY74_RS22000	COG0583	DNA-binding transcription factor activity
BZY74_RS22005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZY74_RS22010	COG4115	mRNA cleavage
BZY74_RS22015	COG2161	toxin-antitoxin pair type II binding
BZY74_RS22035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BZY74_RS22045	COG0131	Imidazoleglycerol-phosphate dehydratase
BZY74_RS22045	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BZY74_RS22050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BZY74_RS22070	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZY74_RS22075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BZY74_RS22080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BZY74_RS22110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BZY74_RS22120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BZY74_RS22135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZY74_RS22140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZY74_RS22150	COG0438	transferase activity, transferring glycosyl groups
BZY74_RS22155	COG2327	Polysaccharide pyruvyl transferase
BZY74_RS22160	COG2244	polysaccharide biosynthetic process
BZY74_RS22165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BZY74_RS22170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BZY74_RS22175	COG0662	Cupin 2, conserved barrel domain protein
BZY74_RS22175	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BZY74_RS22180	COG0297	glycogen (starch) synthase activity
BZY74_RS22185	COG1051	belongs to the nudix hydrolase family
BZY74_RS22190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZY74_RS22195	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BZY74_RS22200	COG0110	maltose O-acetyltransferase activity
BZY74_RS22205	COG1216	Glycosyl transferase, family 2
BZY74_RS22215	COG0438	transferase activity, transferring glycosyl groups
BZY74_RS22220	COG1045	serine acetyltransferase
BZY74_RS22225	COG0463	Glycosyl transferase, family 2
BZY74_RS22230	COG0489	protein tyrosine kinase activity
BZY74_RS22230	COG3206	protein involved in exopolysaccharide biosynthesis
BZY74_RS22235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BZY74_RS22240	COG1596	polysaccharide export
BZY74_RS22245	COG1253	flavin adenine dinucleotide binding
BZY74_RS22250	COG2982	Protein involved in outer membrane biogenesis
BZY74_RS22260	COG0572	uridine kinase
BZY74_RS22265	COG5001	Diguanylate cyclase
BZY74_RS22265	COG3447	MASE1 domain protein
BZY74_RS22265	COG5002	protein histidine kinase activity
BZY74_RS22270	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BZY74_RS22275	COG0443	Heat shock 70 kDa protein
BZY74_RS22280	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
BZY74_RS22285	COG0631	protein serine/threonine phosphatase activity
BZY74_RS22290	COG4245	von Willebrand factor, type A
BZY74_RS22320	COG2205	protein histidine kinase activity
BZY74_RS22325	COG0745	RESPONSE REGULATOR receiver
BZY74_RS22335	COG3609	addiction module antidote protein, CC2985 family
BZY74_RS22345	COG0826	peptidase U32
BZY74_RS22400	COG5301	cellulose 1,4-beta-cellobiosidase activity
BZY74_RS22400	COG5301	cellulose 1,4-beta-cellobiosidase activity
BZY74_RS22490	COG4695	Portal protein
BZY74_RS22545	COG4974	Belongs to the 'phage' integrase family
BZY74_RS22570	COG1063	alcohol dehydrogenase
BZY74_RS22575	COG3775	system Galactitol-specific IIC component
BZY74_RS22580	COG3414	Phosphotransferase system galactitol-specific IIB component
BZY74_RS22585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS22605	COG1830	Aldolase
BZY74_RS22610	COG2211	Major facilitator Superfamily
BZY74_RS22615	COG1397	ADP-ribosylglycohydrolase
BZY74_RS22620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZY74_RS22625	COG2188	Transcriptional regulator
BZY74_RS22630	COG3757	hydrolase, family 25
BZY74_RS22635	COG0351	phosphomethylpyrimidine kinase
BZY74_RS22655	COG5455	response to cobalt ion
BZY74_RS22660	COG3539	Fimbrial protein
BZY74_RS22665	COG3188	usher protein
BZY74_RS22670	COG3121	Chaperone
BZY74_RS22675	COG3539	Fimbrial protein
BZY74_RS22690	COG0489	protein tyrosine kinase activity
BZY74_RS22700	COG3831	ATPase activity
BZY74_RS22705	COG3831	ATPase activity
BZY74_RS22715	COG0714	Associated with various cellular activities
BZY74_RS22720	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BZY74_RS22725	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BZY74_RS22730	COG4715	Zinc finger, swim domain protein
BZY74_RS22735	COG4808	Protein conserved in bacteria
BZY74_RS22740	COG4807	Protein conserved in bacteria
BZY74_RS22745	COG3279	Response regulator of the LytR AlgR family
BZY74_RS22750	COG3275	phosphorelay sensor kinase activity
BZY74_RS22755	COG0789	Transcriptional regulator
BZY74_RS22765	COG1174	glycine betaine transport
BZY74_RS22770	COG1125	glycine betaine transport
BZY74_RS22775	COG1174	glycine betaine transport
BZY74_RS22780	COG1732	Glycine betaine
BZY74_RS22785	COG1472	Belongs to the glycosyl hydrolase 3 family
BZY74_RS22790	COG0277	FAD linked oxidase domain protein
BZY74_RS22795	COG1686	Belongs to the peptidase S11 family
BZY74_RS22805	COG0586	Pfam SNARE associated Golgi protein
BZY74_RS22810	COG1028	Short-chain dehydrogenase reductase Sdr
BZY74_RS22835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZY74_RS22845	COG1346	cytolysis
BZY74_RS22855	COG2949	membrane
BZY74_RS22865	COG0493	'glutamate synthase
BZY74_RS22870	COG0167	dihydroorotate dehydrogenase activity
BZY74_RS22870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BZY74_RS22875	COG4211	Belongs to the binding-protein-dependent transport system permease family
BZY74_RS22880	COG1129	ABC transporter
BZY74_RS22885	COG1879	ABC-type sugar transport system periplasmic component
BZY74_RS22890	COG1609	Transcriptional regulator
BZY74_RS22900	COG2311	Membrane
BZY74_RS22925	COG4771	TonB-dependent receptor
BZY74_RS22935	COG0833	amino acid
BZY74_RS22945	COG0583	DNA-binding transcription factor activity
BZY74_RS22950	COG2855	membrane
BZY74_RS22960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZY74_RS22960	COG1522	sequence-specific DNA binding
BZY74_RS22965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZY74_RS22975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZY74_RS22980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZY74_RS22985	COG2313	pseudouridylate synthase activity
BZY74_RS22990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZY74_RS23005	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BZY74_RS23005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS23005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZY74_RS23010	COG1105	Belongs to the carbohydrate kinase PfkB family
BZY74_RS23015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS23015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZY74_RS23020	COG2814	Major facilitator Superfamily
BZY74_RS23035	COG0246	Mannitol dehydrogenase
BZY74_RS23040	COG0523	cobalamin synthesis protein
BZY74_RS23045	COG0671	phosphoesterase, PA-phosphatase related
BZY74_RS23050	COG0791	NLP P60 protein
BZY74_RS23055	COG2200	EAL domain
BZY74_RS23060	COG4166	transmembrane transport
BZY74_RS23065	COG4174	ABC transporter (Permease)
BZY74_RS23070	COG4239	(ABC) transporter, permease
BZY74_RS23075	COG4172	Belongs to the ABC transporter superfamily
BZY74_RS23090	COG2814	Major facilitator Superfamily
BZY74_RS23095	COG1187	pseudouridine synthase activity
BZY74_RS23105	COG1061	Type III restriction enzyme res subunit
BZY74_RS23125	COG3083	sulfuric ester hydrolase activity
BZY74_RS23145	COG2197	response regulator
BZY74_RS23150	COG3088	subunit of a heme lyase
BZY74_RS23150	COG4235	cytochrome complex assembly
BZY74_RS23155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZY74_RS23160	COG1138	Cytochrome C-type biogenesis protein
BZY74_RS23170	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZY74_RS23175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZY74_RS23180	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZY74_RS23185	COG4133	protoheme IX ABC transporter activity
BZY74_RS23190	COG3005	denitrification pathway
BZY74_RS23195	COG3043	anaerobic respiration
BZY74_RS23200	COG0348	domain, Protein
BZY74_RS23205	COG0437	4 iron, 4 sulfur cluster binding
BZY74_RS23215	COG3062	negative regulation of establishment of protein localization
BZY74_RS23220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS23220	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZY74_RS23240	COG4615	Cyclic peptide transporter
BZY74_RS23245	COG3145	DNA-N1-methyladenine dioxygenase activity
BZY74_RS23250	COG2169	Transcriptional regulator
BZY74_RS23250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZY74_RS23255	COG1477	protein flavinylation
BZY74_RS23260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BZY74_RS23275	COG0642	Histidine kinase
BZY74_RS23275	COG2198	Histidine kinase
BZY74_RS23280	COG2197	response regulator
BZY74_RS23285	COG2205	protein histidine kinase activity
BZY74_RS23285	COG0784	Response regulator, receiver
BZY74_RS23290	COG4676	Protein conserved in bacteria
BZY74_RS23295	COG5445	Predicted secreted protein (DUF2300)
BZY74_RS23300	COG2373	Large extracellular alpha-helical protein
BZY74_RS23305	COG3234	Protein of unknown function (DUF1175)
BZY74_RS23310	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
BZY74_RS23315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BZY74_RS23325	COG3468	outer membrane autotransporter barrel domain protein
BZY74_RS23335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZY74_RS23340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZY74_RS23345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZY74_RS23350	COG3642	lipopolysaccharide core region biosynthetic process
BZY74_RS23360	COG0583	DNA-binding transcription factor activity
BZY74_RS23365	COG0584	glycerophosphoryl diester phosphodiesterase
BZY74_RS23370	COG2271	Major facilitator Superfamily
BZY74_RS23375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZY74_RS23385	COG0247	lactate metabolic process
BZY74_RS23390	COG5464	transposase or invertase
BZY74_RS23460	COG0318	PFAM AMP-dependent synthetase and ligase
BZY74_RS23470	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BZY74_RS23485	COG1169	isochorismate synthase
BZY74_RS23490	COG4575	ribosome binding
BZY74_RS23495	COG2153	protein acetylation
BZY74_RS23530	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZY74_RS23535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BZY74_RS23545	COG0839	Belongs to the complex I subunit 6 family
BZY74_RS23560	COG1034	ATP synthesis coupled electron transport
BZY74_RS23565	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BZY74_RS23570	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BZY74_RS23590	COG0583	DNA-binding transcription factor activity
BZY74_RS23600	COG0436	Aminotransferase
BZY74_RS23610	COG0471	metal ion transport
BZY74_RS23610	COG0490	domain, Protein
BZY74_RS23615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZY74_RS23630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BZY74_RS23635	COG0280	phosphate acetyltransferase
BZY74_RS23635	COG0857	belongs to the CobB CobQ family
BZY74_RS23640	COG1288	antiporter activity
BZY74_RS23645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BZY74_RS23650	COG0622	Phosphoesterase
BZY74_RS23655	COG0625	glutathione transferase activity
BZY74_RS23660	COG0625	glutathione transferase activity
BZY74_RS23665	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BZY74_RS23670	COG1090	epimerase
BZY74_RS23675	COG5464	transposase or invertase
BZY74_RS23680	COG4598	ABC transporter
BZY74_RS23685	COG4160	amino acid transport
BZY74_RS23690	COG4215	(ABC) transporter
BZY74_RS23695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZY74_RS23700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZY74_RS23705	COG0163	prenyltransferase activity
BZY74_RS23710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BZY74_RS23715	COG1286	toxin biosynthetic process
BZY74_RS23720	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BZY74_RS23725	COG0285	dihydrofolate synthase activity
BZY74_RS23735	COG0586	Pfam SNARE associated Golgi protein
BZY74_RS23745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZY74_RS23760	COG2814	Major facilitator Superfamily
BZY74_RS23770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZY74_RS23785	COG3101	peptidyl-lysine hydroxylation
BZY74_RS23790	COG0730	response to heat
BZY74_RS23820	COG3539	Fimbrial protein
BZY74_RS23825	COG3539	Fimbrial protein
BZY74_RS23830	COG3539	Fimbrial protein
BZY74_RS23835	COG3121	Chaperone
BZY74_RS23840	COG3188	usher protein
BZY74_RS23845	COG3539	Fimbrial protein
BZY74_RS23850	COG2062	phosphohistidine phosphatase, SixA
BZY74_RS23865	COG3691	Protein conserved in bacteria
BZY74_RS23875	COG2067	long-chain fatty acid transport protein
BZY74_RS23890	COG2853	Lipoprotein
BZY74_RS23900	COG2116	formate transmembrane transporter activity
BZY74_RS23910	COG0582	viral genome integration into host DNA
BZY74_RS24130	COG0210	DNA helicase
BZY74_RS24215	COG1192	Involved in chromosome partitioning
BZY74_RS24300	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BZY74_RS24365	COG2890	protein-(glutamine-N5) methyltransferase activity
BZY74_RS24440	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BZY74_RS24605	COG3385	transposase activity
BZY74_RS24690	COG0786	glutamate:sodium symporter activity
BZY74_RS24705	COG0640	Transcriptional regulator
BZY74_RS24820	COG3157	Type VI secretion system effector, Hcp
BZY74_RS24835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZY74_RS24855	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BZY74_RS24855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZY74_RS24995	COG2205	protein histidine kinase activity
BZY74_RS25000	COG0745	RESPONSE REGULATOR receiver
BZY74_RS25005	COG1276	copper resistance
BZY74_RS25010	COG2372	response to copper ion
BZY74_RS25015	COG3667	copper resistance
BZY74_RS25020	COG2132	Multicopper oxidase
BZY74_RS25030	COG0739	heme binding
BZY74_RS25060	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZY74_RS25175	COG0789	Transcriptional regulator
BZY74_RS25325	COG3550	peptidyl-serine autophosphorylation
BZY74_RS25450	COG1358	cellular component organization or biogenesis
BZY74_RS25480	COG4245	von Willebrand factor, type A
BZY74_RS25485	COG4245	von Willebrand factor, type A