locus-tag	class	description
IGX36_RS00010	COG0592	DNA-directed DNA polymerase activity
IGX36_RS00020	COG0187	DNA topoisomerase II activity
IGX36_RS00025	COG3753	Protein conserved in bacteria
IGX36_RS00030	COG0561	phosphatase activity
IGX36_RS00040	COG2186	Transcriptional regulator
IGX36_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
IGX36_RS00050	COG0800	Aldolase
IGX36_RS00060	COG2271	Major facilitator Superfamily
IGX36_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
IGX36_RS00075	COG5645	(Lipo)protein
IGX36_RS00095	COG2188	Transcriptional regulator
IGX36_RS00115	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IGX36_RS00120	COG3119	arylsulfatase activity
IGX36_RS00130	COG2149	membrane
IGX36_RS00140	COG0641	radical SAM
IGX36_RS00145	COG2814	Major facilitator Superfamily
IGX36_RS00160	COG0028	Belongs to the TPP enzyme family
IGX36_RS00165	COG0440	acetolactate synthase activity
IGX36_RS00180	COG2197	response regulator
IGX36_RS00185	COG3851	Histidine kinase
IGX36_RS00190	COG2271	Major facilitator Superfamily
IGX36_RS00195	COG2271	Major facilitator Superfamily
IGX36_RS00205	COG2252	PERMEase
IGX36_RS00260	COG0457	Tetratricopeptide repeat
IGX36_RS00270	COG1464	Belongs to the NlpA lipoprotein family
IGX36_RS00275	COG0697	spore germination
IGX36_RS00300	COG2211	Major facilitator Superfamily
IGX36_RS00305	COG1501	Belongs to the glycosyl hydrolase 31 family
IGX36_RS00310	COG3711	transcriptional antiterminator
IGX36_RS00315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS00315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS00315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS00320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS00325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS00325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS00340	COG1940	carbohydrate kinase activity
IGX36_RS00350	COG2982	Protein involved in outer membrane biogenesis
IGX36_RS00355	COG2233	PERMEase
IGX36_RS00360	COG0786	glutamate:sodium symporter activity
IGX36_RS00370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IGX36_RS00375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGX36_RS00380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IGX36_RS00390	COG0194	GDP metabolic process
IGX36_RS00400	COG2860	membrane
IGX36_RS00405	COG3645	SOS response
IGX36_RS00410	COG1561	YicC-like family, N-terminal region
IGX36_RS00435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IGX36_RS00455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IGX36_RS00465	COG1519	Transferase
IGX36_RS00470	COG0859	PFAM glycosyl transferase family 9
IGX36_RS00475	COG0438	transferase activity, transferring glycosyl groups
IGX36_RS00480	COG0515	serine threonine protein kinase
IGX36_RS00495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IGX36_RS00500	COG1442	glycosyl transferase family 8
IGX36_RS00515	COG0859	PFAM glycosyl transferase family 9
IGX36_RS00520	COG0859	PFAM glycosyl transferase family 9
IGX36_RS00530	COG0156	8-amino-7-oxononanoate synthase activity
IGX36_RS00540	COG1216	Glycosyl transferase, family 2
IGX36_RS00545	COG2861	carbohydrate metabolic process
IGX36_RS00550	COG4942	peptidase
IGX36_RS00560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IGX36_RS00565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IGX36_RS00580	COG1045	serine acetyltransferase
IGX36_RS00585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IGX36_RS00595	COG2186	Transcriptional regulator
IGX36_RS00600	COG1620	l-lactate permease
IGX36_RS00605	COG5295	Hep Hag repeat protein
IGX36_RS00625	COG3722	fumarate hydratase activity
IGX36_RS00635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS00635	COG2213	PTS system mannitol-specific
IGX36_RS00645	COG1566	PFAM secretion protein HlyD family protein
IGX36_RS00665	COG0625	glutathione transferase activity
IGX36_RS00675	COG3276	selenocysteine insertion sequence binding
IGX36_RS00690	COG0235	Class ii aldolase
IGX36_RS00695	COG3623	hexulose-6-phosphate isomerase
IGX36_RS00700	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IGX36_RS00710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IGX36_RS00715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IGX36_RS00720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IGX36_RS00725	COG2731	YhcH YjgK YiaL family protein
IGX36_RS00735	COG1414	Transcriptional regulator
IGX36_RS00740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS00750	COG3977	Valine--pyruvate aminotransferase
IGX36_RS00755	COG0366	Alpha amylase catalytic
IGX36_RS00760	COG2992	FlgJ-related protein
IGX36_RS00765	COG1609	Transcriptional regulator
IGX36_RS00765	COG2207	Transcriptional regulator
IGX36_RS00770	COG4214	carbohydrate transport
IGX36_RS00780	COG4213	ABC transporter substrate-binding protein
IGX36_RS00790	COG1070	Carbohydrate kinase
IGX36_RS00800	COG4682	membrane
IGX36_RS00805	COG3274	enterobacterial common antigen metabolic process
IGX36_RS00830	COG1278	Cold shock
IGX36_RS00835	COG2944	sequence-specific DNA binding
IGX36_RS00850	COG2885	chlorophyll binding
IGX36_RS00855	COG0243	molybdopterin cofactor binding
IGX36_RS00860	COG0456	acetyltransferase
IGX36_RS00865	COG2818	Glycosylase
IGX36_RS00870	COG5571	outer membrane autotransporter
IGX36_RS00875	COG2223	nitrite transmembrane transporter activity
IGX36_RS00880	COG2194	sulfuric ester hydrolase activity
IGX36_RS00900	COG0747	negative chemotaxis
IGX36_RS00905	COG0601	transmembrane transport
IGX36_RS00910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGX36_RS00915	COG0444	Belongs to the ABC transporter superfamily
IGX36_RS00920	COG4608	Belongs to the ABC transporter superfamily
IGX36_RS00925	COG0814	amino acid
IGX36_RS00955	COG2200	EAL domain
IGX36_RS00955	COG2199	diguanylate cyclase activity
IGX36_RS00965	COG0612	Peptidase, M16
IGX36_RS00975	COG2200	EAL domain
IGX36_RS00980	COG2982	Protein involved in outer membrane biogenesis
IGX36_RS00985	COG0477	Major facilitator Superfamily
IGX36_RS00990	COG1295	ribonuclease BN
IGX36_RS00995	COG0583	DNA-binding transcription factor activity
IGX36_RS01000	COG2197	response regulator
IGX36_RS01010	COG1858	cytochrome C peroxidase
IGX36_RS01015	COG0076	glutamate decarboxylase activity
IGX36_RS01020	COG2207	Transcriptional regulator
IGX36_RS01025	COG2207	Transcriptional regulator
IGX36_RS01030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IGX36_RS01035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGX36_RS01045	COG2771	luxR family
IGX36_RS01050	COG3247	response to pH
IGX36_RS01065	COG1285	pathogenesis
IGX36_RS01075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGX36_RS01085	COG3721	Heme iron utilization protein
IGX36_RS01095	COG4558	Periplasmic binding protein
IGX36_RS01100	COG4771	TonB-dependent receptor
IGX36_RS01105	COG3720	iron ion transport
IGX36_RS01110	COG2197	response regulator
IGX36_RS01115	COG3065	identical protein binding
IGX36_RS01135	COG1393	Belongs to the ArsC family
IGX36_RS01140	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IGX36_RS01145	COG0640	Transcriptional regulator
IGX36_RS01155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IGX36_RS01160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IGX36_RS01165	COG0339	signal peptide processing
IGX36_RS01175	COG3104	oligopeptide transport
IGX36_RS01180	COG0589	response to stress
IGX36_RS01190	COG0306	phosphate transporter
IGX36_RS01195	COG2081	HI0933 family
IGX36_RS01215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGX36_RS01220	COG1129	ABC transporter
IGX36_RS01220	COG0842	Transport permease protein
IGX36_RS01225	COG0842	Transport permease protein
IGX36_RS01240	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IGX36_RS01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGX36_RS01275	COG0601	transmembrane transport
IGX36_RS01280	COG0747	negative chemotaxis
IGX36_RS01285	COG2091	lysine biosynthetic process via aminoadipic acid
IGX36_RS01290	COG0628	permease
IGX36_RS01305	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IGX36_RS01320	COG3714	YhhN family
IGX36_RS01330	COG3776	membrane
IGX36_RS01335	COG0742	ribosomal rna small subunit methyltransferase
IGX36_RS01340	COG0552	protein localization to endoplasmic reticulum
IGX36_RS01345	COG2884	Cell division ATP-binding protein ftsE
IGX36_RS01350	COG2177	Part of the ABC transporter FtsEX involved in
IGX36_RS01355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGX36_RS01360	COG0683	leucine binding
IGX36_RS01370	COG0456	acetyltransferase
IGX36_RS01375	COG0683	leucine binding
IGX36_RS01380	COG0559	Belongs to the binding-protein-dependent transport system permease family
IGX36_RS01385	COG4177	L-phenylalanine transmembrane transporter activity
IGX36_RS01390	COG0411	ABC transporter
IGX36_RS01395	COG0410	ABC transporter
IGX36_RS01400	COG1653	transport
IGX36_RS01405	COG1175	transmembrane transport
IGX36_RS01420	COG0584	glycerophosphoryl diester phosphodiesterase
IGX36_RS01430	COG0405	Gamma-glutamyltransferase
IGX36_RS01450	COG3157	Type VI secretion system effector, Hcp
IGX36_RS01455	COG1247	-acetyltransferase
IGX36_RS01460	COG0673	inositol 2-dehydrogenase activity
IGX36_RS01465	COG1741	Belongs to the pirin family
IGX36_RS01470	COG1609	Transcriptional regulator
IGX36_RS01475	COG3265	gluconokinase activity
IGX36_RS01480	COG2610	gluconate transmembrane transporter activity
IGX36_RS01485	COG2095	MarC family integral membrane protein
IGX36_RS01490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IGX36_RS01495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IGX36_RS01515	COG0058	SHG alpha-glucan phosphorylase activity
IGX36_RS01525	COG3188	usher protein
IGX36_RS01530	COG3539	Fimbrial protein
IGX36_RS01550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IGX36_RS01565	COG1349	DNA-binding transcription factor activity
IGX36_RS01570	COG4650	regulator
IGX36_RS01575	COG1690	Belongs to the RtcB family
IGX36_RS01590	COG0058	SHG alpha-glucan phosphorylase activity
IGX36_RS01595	COG1640	4-alpha-glucanotransferase
IGX36_RS01600	COG2610	gluconate transmembrane transporter activity
IGX36_RS01610	COG1040	competence protein
IGX36_RS01620	COG5464	transposase or invertase
IGX36_RS01630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IGX36_RS01635	COG1918	ferrous iron import across plasma membrane
IGX36_RS01640	COG2183	response to ionizing radiation
IGX36_RS01645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IGX36_RS01665	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IGX36_RS01675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IGX36_RS01680	COG1011	Hydrolase
IGX36_RS01690	COG0494	nUDIX hydrolase
IGX36_RS01695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IGX36_RS01700	COG4972	Pilus assembly protein
IGX36_RS01705	COG3166	PFAM Fimbrial assembly family protein
IGX36_RS01720	COG4796	Type ii and iii secretion system protein
IGX36_RS01735	COG3266	domain, Protein
IGX36_RS01740	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IGX36_RS01745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IGX36_RS01755	COG0180	Tryptophanyl-tRNA synthetase
IGX36_RS01760	COG2188	Transcriptional regulator
IGX36_RS01770	COG3457	Alanine racemase
IGX36_RS01775	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IGX36_RS01780	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IGX36_RS01795	COG0626	cystathionine gamma-synthase activity
IGX36_RS01810	COG2116	formate transmembrane transporter activity
IGX36_RS01815	COG2146	nitrite reductase [NAD(P)H] activity
IGX36_RS01820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IGX36_RS01830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IGX36_RS01840	COG2184	nucleotidyltransferase activity
IGX36_RS01845	COG0512	Glutamine amidotransferase of anthranilate synthase
IGX36_RS01850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IGX36_RS01855	COG1289	transmembrane transporter activity
IGX36_RS01860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IGX36_RS01865	COG1765	OsmC-like protein
IGX36_RS01870	COG3954	Phosphoribulokinase
IGX36_RS01880	COG0429	hydrolase of the alpha beta-hydrolase fold
IGX36_RS01885	COG0488	(ABC) transporter
IGX36_RS01900	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IGX36_RS01905	COG1047	Peptidyl-prolyl cis-trans
IGX36_RS01915	COG0545	Peptidyl-prolyl cis-trans isomerase
IGX36_RS01920	COG2964	Protein conserved in bacteria
IGX36_RS01990	COG0089	rRNA binding
IGX36_RS02080	COG0201	protein transport
IGX36_RS02120	COG0789	Transcriptional regulator
IGX36_RS02125	COG3036	rescue of stalled ribosome
IGX36_RS02135	COG0569	domain protein
IGX36_RS02155	COG0758	DNA mediated transformation
IGX36_RS02165	COG0551	DNA topoisomerase type I activity
IGX36_RS02185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IGX36_RS02225	COG1126	abc transporter atp-binding protein
IGX36_RS02230	COG0765	amino acid transport
IGX36_RS02235	COG4597	amino acid ABC transporter
IGX36_RS02240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGX36_RS02250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IGX36_RS02255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGX36_RS02260	COG1309	transcriptional regulator
IGX36_RS02270	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IGX36_RS02280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGX36_RS02290	COG4145	pantothenate transmembrane transporter activity
IGX36_RS02295	COG3924	membrane
IGX36_RS02300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGX36_RS02305	COG1349	DNA-binding transcription factor activity
IGX36_RS02315	COG1879	ABC-type sugar transport system periplasmic component
IGX36_RS02320	COG1129	ABC transporter
IGX36_RS02340	COG0439	Biotin carboxylase
IGX36_RS02345	COG0511	ligase activity, forming carbon-carbon bonds
IGX36_RS02350	COG0604	alcohol dehydrogenase
IGX36_RS02355	COG2199	diguanylate cyclase activity
IGX36_RS02355	COG2200	EAL domain
IGX36_RS02360	COG1077	Cell shape determining protein MreB Mrl
IGX36_RS02365	COG1792	Involved in formation and maintenance of cell shape
IGX36_RS02370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IGX36_RS02380	COG1530	ribonuclease E activity
IGX36_RS02385	COG3164	Protein of unknown function
IGX36_RS02390	COG0312	modulator of DNA gyrase
IGX36_RS02395	COG0583	DNA-binding transcription factor activity
IGX36_RS02415	COG2732	(Barnase) inhibitor
IGX36_RS02440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IGX36_RS02445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IGX36_RS02450	COG3105	Protein conserved in bacteria
IGX36_RS02455	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IGX36_RS02470	COG0625	glutathione transferase activity
IGX36_RS02475	COG2969	positive regulation of protein catabolic process
IGX36_RS02480	COG3069	C4-dicarboxylate transmembrane transporter activity
IGX36_RS02510	COG2731	YhcH YjgK YiaL family protein
IGX36_RS02515	COG4804	nuclease activity
IGX36_RS02520	COG0493	'glutamate synthase
IGX36_RS02525	COG0070	glutamate synthase
IGX36_RS02525	COG0069	glutamate synthase activity
IGX36_RS02525	COG0067	glutamate synthase
IGX36_RS02530	COG1242	4 iron, 4 sulfur cluster binding
IGX36_RS02535	COG0784	Response regulator, receiver
IGX36_RS02535	COG2198	Histidine kinase
IGX36_RS02535	COG5002	protein histidine kinase activity
IGX36_RS02540	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IGX36_RS02550	COG0515	serine threonine protein kinase
IGX36_RS02555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS02570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IGX36_RS02575	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IGX36_RS02580	COG1137	ATPase activity
IGX36_RS02585	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IGX36_RS02590	COG3117	lipopolysaccharide transmembrane transporter activity
IGX36_RS02600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IGX36_RS02600	COG0517	IMP dehydrogenase activity
IGX36_RS02605	COG0530	calcium, potassium:sodium antiporter activity
IGX36_RS02610	COG1127	ABC transporter
IGX36_RS02615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IGX36_RS02620	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IGX36_RS02625	COG2854	intermembrane phospholipid transfer
IGX36_RS02630	COG3113	response to antibiotic
IGX36_RS02635	COG5007	Belongs to the BolA IbaG family
IGX36_RS02645	COG3423	Transcriptional regulator
IGX36_RS02650	COG0142	geranyltranstransferase activity
IGX36_RS02665	COG0697	spore germination
IGX36_RS02675	COG2027	D-alanyl-D-alanine carboxypeptidase
IGX36_RS02680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IGX36_RS02685	COG1534	Rna-binding protein
IGX36_RS02695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IGX36_RS02700	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IGX36_RS02710	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IGX36_RS02720	COG2194	sulfuric ester hydrolase activity
IGX36_RS02740	COG0195	Participates in both transcription termination and antitermination
IGX36_RS02780	COG0513	Belongs to the DEAD box helicase family
IGX36_RS02785	COG0814	amino acid
IGX36_RS02790	COG3547	Transposase (IS116 IS110 IS902 family)
IGX36_RS02795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IGX36_RS02800	COG0826	peptidase U32
IGX36_RS02805	COG0826	peptidase U32
IGX36_RS02810	COG3154	lipid carrier protein
IGX36_RS02815	COG3153	acetyltransferase
IGX36_RS02830	COG0693	protein deglycase activity
IGX36_RS02835	COG0702	epimerase
IGX36_RS02840	COG0701	Predicted permease
IGX36_RS02845	COG2823	Periplasmic or secreted lipoprotein
IGX36_RS02865	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IGX36_RS02870	COG0363	glucosamine-6-phosphate deaminase activity
IGX36_RS02875	COG3716	PTS system mannose fructose sorbose family IID component
IGX36_RS02880	COG3715	PTS system
IGX36_RS02885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGX36_RS02895	COG2222	sugar isomerase
IGX36_RS02900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IGX36_RS02905	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS02910	COG3716	PTS system mannose fructose sorbose family IID component
IGX36_RS02920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGX36_RS02930	COG1349	DNA-binding transcription factor activity
IGX36_RS02940	COG2002	toxin-antitoxin pair type II binding
IGX36_RS02945	COG2721	sulfolactate sulfo-lyase activity
IGX36_RS02950	COG2271	Major facilitator Superfamily
IGX36_RS02960	COG2084	Dehydrogenase
IGX36_RS02965	COG1929	Belongs to the glycerate kinase type-1 family
IGX36_RS02990	COG0583	DNA-binding transcription factor activity
IGX36_RS02995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IGX36_RS03005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGX36_RS03010	COG1882	Formate acetyltransferase
IGX36_RS03015	COG0251	oxidation-reduction process
IGX36_RS03020	COG1760	l-serine dehydratase
IGX36_RS03025	COG0814	amino acid
IGX36_RS03040	COG1741	Belongs to the pirin family
IGX36_RS03045	COG0583	DNA-binding transcription factor activity
IGX36_RS03050	COG3152	Membrane
IGX36_RS03055	COG3152	Membrane
IGX36_RS03060	COG0435	Glutathione S-transferase
IGX36_RS03065	COG2259	Doxx family
IGX36_RS03075	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IGX36_RS03080	COG4575	ribosome binding
IGX36_RS03085	COG1422	Protein of unknown function (DUF1090)
IGX36_RS03095	COG0586	Pfam SNARE associated Golgi protein
IGX36_RS03100	COG2186	Transcriptional regulator
IGX36_RS03105	COG2271	Major facilitator Superfamily
IGX36_RS03115	COG2721	sulfolactate sulfo-lyase activity
IGX36_RS03125	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IGX36_RS03130	COG0861	Integral membrane protein TerC family
IGX36_RS03135	COG0673	inositol 2-dehydrogenase activity
IGX36_RS03140	COG2949	membrane
IGX36_RS03145	COG1451	nucleotide metabolic process
IGX36_RS03155	COG1902	pentaerythritol trinitrate reductase activity
IGX36_RS03155	COG0446	pyridine nucleotide-disulphide oxidoreductase
IGX36_RS03165	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IGX36_RS03165	COG3408	Glycogen debranching enzyme
IGX36_RS03175	COG0531	amino acid
IGX36_RS03180	COG2731	YhcH YjgK YiaL family protein
IGX36_RS03185	COG3250	beta-galactosidase activity
IGX36_RS03190	COG1609	Transcriptional regulator
IGX36_RS03195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IGX36_RS03205	COG0840	transmembrane signaling receptor activity
IGX36_RS03210	COG1695	Transcriptional regulator
IGX36_RS03215	COG2375	cellular response to nickel ion
IGX36_RS03230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGX36_RS03235	COG0358	DNA primase activity
IGX36_RS03240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IGX36_RS03250	COG0471	metal ion transport
IGX36_RS03255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IGX36_RS03260	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IGX36_RS03275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IGX36_RS03290	COG4991	sh3 domain protein
IGX36_RS03295	COG3025	triphosphatase activity
IGX36_RS03320	COG2268	Band 7 protein
IGX36_RS03325	COG1585	Membrane protein implicated in regulation of membrane protease activity
IGX36_RS03345	COG3539	Fimbrial protein
IGX36_RS03350	COG3121	Chaperone
IGX36_RS03355	COG3188	usher protein
IGX36_RS03360	COG3539	Fimbrial protein
IGX36_RS03375	COG3384	dioxygenase
IGX36_RS03380	COG0754	glutathionylspermidine amidase activity
IGX36_RS03390	COG1538	Outer membrane efflux protein
IGX36_RS03395	COG0494	nUDIX hydrolase
IGX36_RS03400	COG3151	Protein conserved in bacteria
IGX36_RS03405	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IGX36_RS03410	COG3150	esterase
IGX36_RS03415	COG0187	DNA topoisomerase II activity
IGX36_RS03430	COG1120	ATPase activity
IGX36_RS03435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGX36_RS03440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGX36_RS03450	COG1737	Transcriptional regulator
IGX36_RS03455	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IGX36_RS03460	COG2249	NAD(P)H dehydrogenase (quinone) activity
IGX36_RS03465	COG0642	Histidine kinase
IGX36_RS03470	COG0745	RESPONSE REGULATOR receiver
IGX36_RS03475	COG3111	PFAM Bacterial OB fold (BOF) protein
IGX36_RS03480	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IGX36_RS03485	COG4166	transmembrane transport
IGX36_RS03490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGX36_RS03495	COG0204	Acyl-transferase
IGX36_RS03500	COG2132	Multicopper oxidase
IGX36_RS03505	COG1032	radical SAM domain protein
IGX36_RS03510	COG4238	major outer membrane lipoprotein
IGX36_RS03520	COG0656	L-ascorbic acid biosynthetic process
IGX36_RS03525	COG1979	alcohol dehydrogenase
IGX36_RS03530	COG2207	Transcriptional regulator
IGX36_RS03535	COG0586	Pfam SNARE associated Golgi protein
IGX36_RS03540	COG0626	cystathionine gamma-synthase activity
IGX36_RS03545	COG0811	peptide transport
IGX36_RS03550	COG0848	biopolymer transport protein
IGX36_RS03555	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS03565	COG0667	Aldo Keto reductase
IGX36_RS03580	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IGX36_RS03585	COG0437	4 iron, 4 sulfur cluster binding
IGX36_RS03590	COG5557	Pfam Polysulphide reductase, NrfD
IGX36_RS03595	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IGX36_RS03600	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IGX36_RS03605	COG1773	rubredoxin
IGX36_RS03615	COG0298	carbon dioxide binding
IGX36_RS03620	COG0625	glutathione transferase activity
IGX36_RS03625	COG0754	glutathionylspermidine amidase activity
IGX36_RS03630	COG0306	phosphate transporter
IGX36_RS03635	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IGX36_RS03640	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IGX36_RS03645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IGX36_RS03650	COG2244	polysaccharide biosynthetic process
IGX36_RS03660	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IGX36_RS03675	COG0156	8-amino-7-oxononanoate synthase activity
IGX36_RS03680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGX36_RS03690	COG0318	PFAM AMP-dependent synthetase and ligase
IGX36_RS03695	COG0456	acetyltransferase
IGX36_RS03700	COG2186	Transcriptional regulator
IGX36_RS03705	COG0277	FAD linked oxidase domain protein
IGX36_RS03710	COG0277	FAD linked oxidase domain protein
IGX36_RS03715	COG0247	lactate metabolic process
IGX36_RS03720	COG3193	protein, possibly involved in utilization of glycolate and propanediol
IGX36_RS03725	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IGX36_RS03730	COG1620	l-lactate permease
IGX36_RS03735	COG3064	Membrane
IGX36_RS03740	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IGX36_RS03760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IGX36_RS03765	COG1459	type II secretion system
IGX36_RS03770	COG2165	general secretion pathway protein
IGX36_RS03800	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IGX36_RS03925	COG3547	Transposase (IS116 IS110 IS902 family)
IGX36_RS03945	COG0582	viral genome integration into host DNA
IGX36_RS03955	COG1811	Na channel or pump
IGX36_RS03960	COG1982	Orn Lys Arg decarboxylase major
IGX36_RS03965	COG2211	Major facilitator Superfamily
IGX36_RS03980	COG1194	a g-specific adenine glycosylase
IGX36_RS03990	COG3171	Protein conserved in bacteria
IGX36_RS04000	COG0252	asparaginase activity
IGX36_RS04015	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IGX36_RS04020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IGX36_RS04025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IGX36_RS04040	COG0762	integral membrane protein
IGX36_RS04045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IGX36_RS04050	COG2805	Type II/IV secretion system protein
IGX36_RS04065	COG0189	ligase activity
IGX36_RS04070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IGX36_RS04075	COG2356	endonuclease I
IGX36_RS04085	COG2814	Major facilitator Superfamily
IGX36_RS04105	COG1166	arginine decarboxylase activity
IGX36_RS04120	COG0501	Belongs to the peptidase M48B family
IGX36_RS04125	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IGX36_RS04130	COG0330	HflC and HflK could
IGX36_RS04135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS04140	COG2213	PTS system mannitol-specific
IGX36_RS04145	COG1063	alcohol dehydrogenase
IGX36_RS04150	COG1494	fructose-1,6-bisphosphatase
IGX36_RS04160	COG1072	(Pantothenic acid kinase))
IGX36_RS04175	COG0191	fructose-bisphosphate aldolase activity
IGX36_RS04180	COG0668	transmembrane transport
IGX36_RS04185	COG1279	arginine transmembrane transporter activity
IGX36_RS04190	COG2968	Membrane
IGX36_RS04195	COG0583	DNA-binding transcription factor activity
IGX36_RS04200	COG0427	acetyl-CoA hydrolase
IGX36_RS04205	COG1024	Enoyl-CoA hydratase
IGX36_RS04210	COG1703	isobutyryl-CoA mutase activity
IGX36_RS04215	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IGX36_RS04215	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IGX36_RS04235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IGX36_RS04245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IGX36_RS04265	COG0006	proline dipeptidase activity
IGX36_RS04270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IGX36_RS04275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IGX36_RS04300	COG2723	6-phospho-beta-galactosidase activity
IGX36_RS04310	COG1272	protein, Hemolysin III
IGX36_RS04320	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IGX36_RS04330	COG0716	FMN binding
IGX36_RS04335	COG4974	Belongs to the 'phage' integrase family
IGX36_RS04340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IGX36_RS04345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IGX36_RS04355	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IGX36_RS04375	COG2233	PERMEase
IGX36_RS04380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS04380	COG0493	'glutamate synthase
IGX36_RS04385	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS04390	COG2252	PERMEase
IGX36_RS04395	COG0402	S-adenosylhomocysteine deaminase activity
IGX36_RS04400	COG2233	PERMEase
IGX36_RS04405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IGX36_RS04405	COG2080	2 iron, 2 sulfur cluster binding
IGX36_RS04410	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IGX36_RS04415	COG0402	S-adenosylhomocysteine deaminase activity
IGX36_RS04420	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS04420	COG0493	'glutamate synthase
IGX36_RS04425	COG2068	MobA-Related Protein
IGX36_RS04430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IGX36_RS04435	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IGX36_RS04435	COG3608	succinylglutamate desuccinylase aspartoacylase
IGX36_RS04440	COG0549	Belongs to the carbamate kinase family
IGX36_RS04450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IGX36_RS04455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IGX36_RS04460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IGX36_RS04465	COG3829	transcription factor binding
IGX36_RS04470	COG2080	2 iron, 2 sulfur cluster binding
IGX36_RS04475	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IGX36_RS04480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IGX36_RS04485	COG4942	peptidase
IGX36_RS04580	COG3387	PFAM Glycoside hydrolase 15-related
IGX36_RS04590	COG2207	Transcriptional regulator
IGX36_RS04695	COG2197	response regulator
IGX36_RS04700	COG0741	lytic transglycosylase activity
IGX36_RS04715	COG0457	Tetratricopeptide repeat
IGX36_RS04740	COG3710	Transcriptional regulator
IGX36_RS04750	COG2771	luxR family
IGX36_RS04755	COG0814	amino acid
IGX36_RS04760	COG0183	Belongs to the thiolase family
IGX36_RS04770	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS04775	COG2814	Major facilitator Superfamily
IGX36_RS04780	COG1794	racemase activity, acting on amino acids and derivatives
IGX36_RS04785	COG0583	DNA-binding transcription factor activity
IGX36_RS04795	COG1609	Transcriptional regulator
IGX36_RS04810	COG0667	Aldo Keto reductase
IGX36_RS04820	COG0861	Integral membrane protein TerC family
IGX36_RS04835	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
IGX36_RS04850	COG2165	general secretion pathway protein
IGX36_RS04855	COG4795	General secretion pathway protein
IGX36_RS04865	COG4967	type IV pilus modification protein PilV
IGX36_RS04870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IGX36_RS04880	COG1074	ATP-dependent DNA helicase activity
IGX36_RS04885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IGX36_RS04890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IGX36_RS04890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IGX36_RS04895	COG0860	N-Acetylmuramoyl-L-alanine amidase
IGX36_RS04910	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IGX36_RS04915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IGX36_RS04920	COG2166	iron-sulfur cluster assembly
IGX36_RS04925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IGX36_RS04935	COG0583	DNA-binding transcription factor activity
IGX36_RS04940	COG2363	Small membrane protein
IGX36_RS04950	COG1349	DNA-binding transcription factor activity
IGX36_RS04960	COG1070	Carbohydrate kinase
IGX36_RS04970	COG0738	Major facilitator superfamily
IGX36_RS04975	COG0235	Class ii aldolase
IGX36_RS04980	COG1454	alcohol dehydrogenase
IGX36_RS04990	COG1760	l-serine dehydratase
IGX36_RS04995	COG0814	amino acid
IGX36_RS05000	COG1611	Belongs to the LOG family
IGX36_RS05015	COG3098	single-species biofilm formation
IGX36_RS05020	COG0564	pseudouridine synthase activity
IGX36_RS05025	COG0716	FMN binding
IGX36_RS05030	COG2271	Major facilitator Superfamily
IGX36_RS05035	COG4948	Mandelate Racemase Muconate Lactonizing
IGX36_RS05040	COG4948	Mandelate Racemase Muconate Lactonizing
IGX36_RS05045	COG4999	Histidine kinase
IGX36_RS05045	COG3437	response regulator, receiver
IGX36_RS05045	COG2205	protein histidine kinase activity
IGX36_RS05045	COG3850	Histidine kinase
IGX36_RS05055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IGX36_RS05060	COG3956	TIGRFAM MazG family protein
IGX36_RS05085	COG0602	queuosine metabolic process
IGX36_RS05095	COG2223	nitrite transmembrane transporter activity
IGX36_RS05100	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS05105	COG0277	FAD linked oxidase domain protein
IGX36_RS05110	COG0477	Major facilitator Superfamily
IGX36_RS05115	COG2086	electron transfer activity
IGX36_RS05120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IGX36_RS05125	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IGX36_RS05130	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IGX36_RS05135	COG0644	oxidoreductase
IGX36_RS05140	COG0720	synthase
IGX36_RS05165	COG1203	CRISPR-associated helicase, Cas3
IGX36_RS05180	COG1857	crispr-associated protein
IGX36_RS05195	COG1518	maintenance of DNA repeat elements
IGX36_RS05200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IGX36_RS05205	COG2234	aminopeptidase activity
IGX36_RS05260	COG1388	LysM domain
IGX36_RS05260	COG4942	peptidase
IGX36_RS05265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGX36_RS05275	COG0163	prenyltransferase activity
IGX36_RS05280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IGX36_RS05300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IGX36_RS05325	COG3604	Transcriptional regulator
IGX36_RS05330	COG0309	Hydrogenase expression formation protein (HypE)
IGX36_RS05335	COG0409	Hydrogenase expression formation protein
IGX36_RS05340	COG0298	carbon dioxide binding
IGX36_RS05345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IGX36_RS05350	COG0375	protein maturation
IGX36_RS05360	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS05365	COG0651	ATP synthesis coupled electron transport
IGX36_RS05370	COG0650	Formate hydrogenlyase subunit 4
IGX36_RS05375	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IGX36_RS05375	COG3261	NADH dehydrogenase
IGX36_RS05380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGX36_RS05385	COG3260	NADH ubiquinone oxidoreductase 20
IGX36_RS05395	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IGX36_RS05400	COG4680	protein conserved in bacteria
IGX36_RS05405	COG5499	transcription regulator containing HTH domain
IGX36_RS05410	COG2723	6-phospho-beta-galactosidase activity
IGX36_RS05415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGX36_RS05415	COG1263	PTS System
IGX36_RS05420	COG1609	Transcriptional regulator
IGX36_RS05425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS05430	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IGX36_RS05455	COG1349	DNA-binding transcription factor activity
IGX36_RS05460	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS05475	COG3732	PTS system glucitol sorbitol-specific
IGX36_RS05480	COG3730	PTS system glucitol sorbitol-specific
IGX36_RS05485	COG2951	lytic endotransglycosylase activity
IGX36_RS05490	COG1546	Belongs to the CinA family
IGX36_RS05510	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IGX36_RS05535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IGX36_RS05540	COG1238	metal cluster binding
IGX36_RS05560	COG2814	Major facilitator Superfamily
IGX36_RS05565	COG1566	PFAM secretion protein HlyD family protein
IGX36_RS05570	COG1846	Transcriptional regulator
IGX36_RS05580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IGX36_RS05585	COG2814	Major facilitator Superfamily
IGX36_RS05590	COG2113	Glycine betaine
IGX36_RS05595	COG4176	ABC-type proline glycine betaine transport system permease component
IGX36_RS05600	COG4175	Glycine betaine
IGX36_RS05605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGX36_RS05610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGX36_RS05620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IGX36_RS05625	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IGX36_RS05630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IGX36_RS05635	COG4575	ribosome binding
IGX36_RS05650	COG2916	Histone family protein nucleoid-structuring protein H-NS
IGX36_RS05655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IGX36_RS05660	COG0640	Transcriptional regulator
IGX36_RS05665	COG0401	homolog of Blt101
IGX36_RS05670	COG1652	LysM domain
IGX36_RS05675	COG1802	Transcriptional regulator
IGX36_RS05680	COG1113	amino acid transport
IGX36_RS05685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IGX36_RS05690	COG1012	belongs to the aldehyde dehydrogenase family
IGX36_RS05695	COG0579	oxidoreductase
IGX36_RS05720	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IGX36_RS05725	COG0732	type I restriction modification DNA specificity domain
IGX36_RS05730	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IGX36_RS05745	COG1475	DNA binding
IGX36_RS05755	COG0582	viral genome integration into host DNA
IGX36_RS05770	COG2867	negative regulation of translational initiation
IGX36_RS05780	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IGX36_RS05785	COG0497	DNA recombination
IGX36_RS05800	COG4536	flavin adenine dinucleotide binding
IGX36_RS05805	COG4137	Cytochrome C assembly protein
IGX36_RS05810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IGX36_RS05835	COG2885	chlorophyll binding
IGX36_RS05855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IGX36_RS05860	COG1605	Chorismate mutase
IGX36_RS05860	COG0287	Prephenate dehydrogenase
IGX36_RS05865	COG0077	Prephenate dehydratase
IGX36_RS05865	COG1605	Chorismate mutase
IGX36_RS06020	COG2314	TM2 domain
IGX36_RS06035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IGX36_RS06040	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IGX36_RS06045	COG0564	pseudouridine synthase activity
IGX36_RS06055	COG0542	response to heat
IGX36_RS06085	COG5544	Lipoprotein
IGX36_RS06090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGX36_RS06095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IGX36_RS06095	COG1042	CoA-binding domain protein
IGX36_RS06095	COG0045	succinate-CoA ligase (ADP-forming) activity
IGX36_RS06100	COG3148	PFAM DTW domain containing protein
IGX36_RS06105	COG3118	belongs to the thioredoxin family
IGX36_RS06110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGX36_RS06130	COG0583	DNA-binding transcription factor activity
IGX36_RS06135	COG0513	Belongs to the DEAD box helicase family
IGX36_RS06145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IGX36_RS06155	COG1595	DNA-templated transcription, initiation
IGX36_RS06160	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IGX36_RS06165	COG3026	antisigma factor binding
IGX36_RS06170	COG3086	response to oxidative stress
IGX36_RS06180	COG0681	Belongs to the peptidase S26 family
IGX36_RS06200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IGX36_RS06215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS06220	COG1737	Transcriptional regulator
IGX36_RS06225	COG0560	Phosphoserine phosphatase
IGX36_RS06240	COG0047	phosphoribosylformylglycinamidine synthase activity
IGX36_RS06240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGX36_RS06245	COG2205	protein histidine kinase activity
IGX36_RS06250	COG3170	Tfp pilus assembly protein FimV
IGX36_RS06255	COG2204	response regulator
IGX36_RS06260	COG0347	Belongs to the P(II) protein family
IGX36_RS06265	COG1017	nitric oxide dioxygenase activity
IGX36_RS06265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IGX36_RS06275	COG1940	carbohydrate kinase activity
IGX36_RS06280	COG0457	Tetratricopeptide repeat
IGX36_RS06285	COG1879	ABC-type sugar transport system periplasmic component
IGX36_RS06290	COG1879	ABC-type sugar transport system periplasmic component
IGX36_RS06295	COG1129	ABC transporter
IGX36_RS06300	COG1172	Belongs to the binding-protein-dependent transport system permease family
IGX36_RS06305	COG1063	alcohol dehydrogenase
IGX36_RS06310	COG2017	converts alpha-aldose to the beta-anomer
IGX36_RS06315	COG2259	Doxx family
IGX36_RS06340	COG4638	Rieske (2fe-2S)
IGX36_RS06345	COG0583	DNA-binding transcription factor activity
IGX36_RS06350	COG2814	Major facilitator Superfamily
IGX36_RS06355	COG3711	transcriptional antiterminator
IGX36_RS06365	COG0483	inositol monophosphate 1-phosphatase activity
IGX36_RS06385	COG0822	iron-sulfur transferase activity
IGX36_RS06405	COG0633	Ferredoxin
IGX36_RS06410	COG2975	iron-sulfur cluster assembly
IGX36_RS06425	COG2897	thiosulfate sulfurtransferase activity
IGX36_RS06430	COG2373	Large extracellular alpha-helical protein
IGX36_RS06435	COG4953	penicillin-binding protein 1C
IGX36_RS06465	COG2976	Protein conserved in bacteria
IGX36_RS06480	COG1645	bacterial-type flagellum-dependent swarming motility
IGX36_RS06505	COG0516	GMP reductase activity
IGX36_RS06505	COG0517	IMP dehydrogenase activity
IGX36_RS06545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IGX36_RS06670	COG3179	chitinase
IGX36_RS06710	COG2200	EAL domain
IGX36_RS06725	COG0248	Ppx GppA phosphatase
IGX36_RS06730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IGX36_RS06735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IGX36_RS06750	COG2233	PERMEase
IGX36_RS06760	COG1393	Belongs to the ArsC family
IGX36_RS06765	COG4783	chaperone-mediated protein folding
IGX36_RS06770	COG0628	permease
IGX36_RS06775	COG2116	formate transmembrane transporter activity
IGX36_RS06780	COG3604	Transcriptional regulator
IGX36_RS06790	COG3260	NADH ubiquinone oxidoreductase 20
IGX36_RS06795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGX36_RS06800	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IGX36_RS06800	COG3261	NADH dehydrogenase
IGX36_RS06805	COG0651	ATP synthesis coupled electron transport
IGX36_RS06810	COG4237	Hydrogenase 4 membrane
IGX36_RS06820	COG0650	Formate hydrogenlyase subunit 4
IGX36_RS06825	COG0651	ATP synthesis coupled electron transport
IGX36_RS06830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS06835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IGX36_RS06840	COG2716	regulation of RNA biosynthetic process
IGX36_RS06850	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IGX36_RS06865	COG2321	neutral zinc metallopeptidase
IGX36_RS06875	COG0400	carboxylic ester hydrolase activity
IGX36_RS06890	COG1393	Belongs to the ArsC family
IGX36_RS06900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IGX36_RS06905	COG3850	Histidine kinase
IGX36_RS06910	COG0493	'glutamate synthase
IGX36_RS06910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS06920	COG5342	invasion associated locus B
IGX36_RS06925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IGX36_RS06930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IGX36_RS06935	COG0280	phosphate acetyltransferase
IGX36_RS06935	COG0281	malic enzyme
IGX36_RS06940	COG4810	utilization protein
IGX36_RS06945	COG4917	ethanolamine utilization protein
IGX36_RS06950	COG4766	ethanolamine catabolic process
IGX36_RS06955	COG4812	Cobalamin adenosyltransferase
IGX36_RS06960	COG0280	phosphate acetyltransferase
IGX36_RS06965	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IGX36_RS06970	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IGX36_RS06975	COG1012	belongs to the aldehyde dehydrogenase family
IGX36_RS06980	COG4820	ethanolamine utilization protein (EutJ)
IGX36_RS06985	COG1454	alcohol dehydrogenase
IGX36_RS06990	COG3192	ethanolamine utilization protein
IGX36_RS06995	COG4819	ethanolamine utilization protein
IGX36_RS07000	COG4303	Ethanolamine ammonia lyase large subunit
IGX36_RS07010	COG4816	utilization protein
IGX36_RS07015	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IGX36_RS07020	COG2207	Transcriptional regulator
IGX36_RS07030	COG0860	N-Acetylmuramoyl-L-alanine amidase
IGX36_RS07050	COG2837	iron assimilation
IGX36_RS07055	COG1263	PTS System
IGX36_RS07055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGX36_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS07075	COG4150	thiosulfate binding
IGX36_RS07080	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IGX36_RS07085	COG4208	sulfate ABC transporter
IGX36_RS07090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IGX36_RS07095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IGX36_RS07110	COG2190	(PTS) system
IGX36_RS07115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGX36_RS07120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS07125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IGX36_RS07135	COG3115	cell septum assembly
IGX36_RS07145	COG3530	Putative quorum-sensing-regulated virulence factor
IGX36_RS07150	COG0385	Bile acid
IGX36_RS07155	COG0583	DNA-binding transcription factor activity
IGX36_RS07165	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IGX36_RS07170	COG2211	Major facilitator Superfamily
IGX36_RS07180	COG0583	DNA-binding transcription factor activity
IGX36_RS07220	COG0675	Transposase, IS605 OrfB family
IGX36_RS07225	COG3415	Transposase
IGX36_RS07230	COG3415	Transposase
IGX36_RS07245	COG2200	EAL domain
IGX36_RS07245	COG2199	diguanylate cyclase activity
IGX36_RS07255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IGX36_RS07280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS07285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS07290	COG0006	proline dipeptidase activity
IGX36_RS07295	COG1363	Peptidase, m42
IGX36_RS07300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS07300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGX36_RS07300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS07305	COG2207	Transcriptional regulator
IGX36_RS07310	COG3279	Response regulator of the LytR AlgR family
IGX36_RS07315	COG3275	phosphorelay sensor kinase activity
IGX36_RS07320	COG0436	Aminotransferase
IGX36_RS07330	COG1560	Kdo2-lipid A biosynthetic process
IGX36_RS07355	COG0028	Belongs to the TPP enzyme family
IGX36_RS07360	COG0679	Auxin Efflux Carrier
IGX36_RS07370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IGX36_RS07375	COG2205	protein histidine kinase activity
IGX36_RS07375	COG2198	Histidine kinase
IGX36_RS07375	COG0784	Response regulator, receiver
IGX36_RS07375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGX36_RS07510	COG2246	polysaccharide biosynthetic process
IGX36_RS07515	COG0582	viral genome integration into host DNA
IGX36_RS07590	COG0582	viral genome integration into host DNA
IGX36_RS07600	COG2116	formate transmembrane transporter activity
IGX36_RS07605	COG2853	Lipoprotein
IGX36_RS07615	COG2067	long-chain fatty acid transport protein
IGX36_RS07620	COG3691	Protein conserved in bacteria
IGX36_RS07635	COG2062	phosphohistidine phosphatase, SixA
IGX36_RS07640	COG3539	Fimbrial protein
IGX36_RS07650	COG3121	Chaperone
IGX36_RS07655	COG3539	Fimbrial protein
IGX36_RS07660	COG3539	Fimbrial protein
IGX36_RS07665	COG3539	Fimbrial protein
IGX36_RS07695	COG0730	response to heat
IGX36_RS07700	COG3101	peptidyl-lysine hydroxylation
IGX36_RS07715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IGX36_RS07720	COG2814	Major facilitator Superfamily
IGX36_RS07795	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IGX36_RS07820	COG4695	Portal protein
IGX36_RS07910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IGX36_RS07920	COG0586	Pfam SNARE associated Golgi protein
IGX36_RS07930	COG0285	dihydrofolate synthase activity
IGX36_RS07935	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IGX36_RS07940	COG1286	toxin biosynthetic process
IGX36_RS07945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IGX36_RS07950	COG0163	prenyltransferase activity
IGX36_RS07955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGX36_RS07960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGX36_RS07965	COG4215	(ABC) transporter
IGX36_RS07970	COG4160	amino acid transport
IGX36_RS07975	COG4598	ABC transporter
IGX36_RS07980	COG5464	transposase or invertase
IGX36_RS07985	COG1090	epimerase
IGX36_RS07990	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IGX36_RS07995	COG0625	glutathione transferase activity
IGX36_RS08000	COG0625	glutathione transferase activity
IGX36_RS08005	COG0622	Phosphoesterase
IGX36_RS08010	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IGX36_RS08015	COG1288	antiporter activity
IGX36_RS08020	COG0280	phosphate acetyltransferase
IGX36_RS08020	COG0857	belongs to the CobB CobQ family
IGX36_RS08025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGX36_RS08040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IGX36_RS08045	COG0490	domain, Protein
IGX36_RS08045	COG0471	metal ion transport
IGX36_RS08055	COG0436	Aminotransferase
IGX36_RS08060	COG0583	DNA-binding transcription factor activity
IGX36_RS08080	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IGX36_RS08085	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IGX36_RS08090	COG1034	ATP synthesis coupled electron transport
IGX36_RS08105	COG0839	Belongs to the complex I subunit 6 family
IGX36_RS08115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IGX36_RS08120	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGX36_RS08135	COG2234	aminopeptidase activity
IGX36_RS08155	COG4575	ribosome binding
IGX36_RS08160	COG1169	isochorismate synthase
IGX36_RS08175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IGX36_RS08185	COG0318	PFAM AMP-dependent synthetase and ligase
IGX36_RS08250	COG1414	Transcriptional regulator
IGX36_RS08260	COG2271	Major facilitator Superfamily
IGX36_RS08270	COG5464	transposase or invertase
IGX36_RS08275	COG0247	lactate metabolic process
IGX36_RS08285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IGX36_RS08290	COG2271	Major facilitator Superfamily
IGX36_RS08295	COG0584	glycerophosphoryl diester phosphodiesterase
IGX36_RS08300	COG0583	DNA-binding transcription factor activity
IGX36_RS08305	COG2814	Major facilitator Superfamily
IGX36_RS08310	COG3642	lipopolysaccharide core region biosynthetic process
IGX36_RS08315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IGX36_RS08320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGX36_RS08325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGX36_RS08330	COG3468	outer membrane autotransporter barrel domain protein
IGX36_RS08340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGX36_RS08345	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
IGX36_RS08350	COG3234	Protein of unknown function (DUF1175)
IGX36_RS08355	COG2373	Large extracellular alpha-helical protein
IGX36_RS08360	COG5445	Predicted secreted protein (DUF2300)
IGX36_RS08365	COG4676	Protein conserved in bacteria
IGX36_RS08370	COG0183	Belongs to the thiolase family
IGX36_RS08375	COG2031	fatty acid transporter
IGX36_RS08380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IGX36_RS08385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IGX36_RS08390	COG2204	response regulator
IGX36_RS08400	COG2205	protein histidine kinase activity
IGX36_RS08400	COG0784	Response regulator, receiver
IGX36_RS08405	COG2197	response regulator
IGX36_RS08410	COG2198	Histidine kinase
IGX36_RS08410	COG0642	Histidine kinase
IGX36_RS08415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IGX36_RS08420	COG1477	protein flavinylation
IGX36_RS08425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IGX36_RS08425	COG2169	Transcriptional regulator
IGX36_RS08430	COG3145	DNA-N1-methyladenine dioxygenase activity
IGX36_RS08435	COG4615	Cyclic peptide transporter
IGX36_RS08450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS08450	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IGX36_RS08455	COG3062	negative regulation of establishment of protein localization
IGX36_RS08465	COG0437	4 iron, 4 sulfur cluster binding
IGX36_RS08470	COG0348	domain, Protein
IGX36_RS08475	COG3043	anaerobic respiration
IGX36_RS08480	COG3005	denitrification pathway
IGX36_RS08485	COG4133	protoheme IX ABC transporter activity
IGX36_RS08490	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IGX36_RS08495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IGX36_RS08500	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IGX36_RS08510	COG1138	Cytochrome C-type biogenesis protein
IGX36_RS08515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IGX36_RS08520	COG4235	cytochrome complex assembly
IGX36_RS08520	COG3088	subunit of a heme lyase
IGX36_RS08525	COG2197	response regulator
IGX36_RS08530	COG3468	outer membrane autotransporter barrel domain protein
IGX36_RS08540	COG3083	sulfuric ester hydrolase activity
IGX36_RS08560	COG1061	Type III restriction enzyme res subunit
IGX36_RS08565	COG1187	pseudouridine synthase activity
IGX36_RS08570	COG2814	Major facilitator Superfamily
IGX36_RS08580	COG4172	Belongs to the ABC transporter superfamily
IGX36_RS08585	COG4239	(ABC) transporter, permease
IGX36_RS08590	COG4174	ABC transporter (Permease)
IGX36_RS08595	COG4166	transmembrane transport
IGX36_RS08600	COG2200	EAL domain
IGX36_RS08605	COG0791	NLP P60 protein
IGX36_RS08610	COG0671	phosphoesterase, PA-phosphatase related
IGX36_RS08615	COG0523	cobalamin synthesis protein
IGX36_RS08620	COG0246	Mannitol dehydrogenase
IGX36_RS08635	COG2814	Major facilitator Superfamily
IGX36_RS08640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS08640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS08645	COG1105	Belongs to the carbohydrate kinase PfkB family
IGX36_RS08650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS08650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS08650	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IGX36_RS08660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGX36_RS08665	COG2313	pseudouridylate synthase activity
IGX36_RS08670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IGX36_RS08675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IGX36_RS08685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IGX36_RS08690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGX36_RS08690	COG1522	sequence-specific DNA binding
IGX36_RS08700	COG2855	membrane
IGX36_RS08705	COG0583	DNA-binding transcription factor activity
IGX36_RS08710	COG0833	amino acid
IGX36_RS08715	COG4771	TonB-dependent receptor
IGX36_RS08730	COG2311	Membrane
IGX36_RS08735	COG1609	Transcriptional regulator
IGX36_RS08740	COG1879	ABC-type sugar transport system periplasmic component
IGX36_RS08745	COG1129	ABC transporter
IGX36_RS08750	COG4211	Belongs to the binding-protein-dependent transport system permease family
IGX36_RS08755	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IGX36_RS08755	COG0167	dihydroorotate dehydrogenase activity
IGX36_RS08760	COG0493	'glutamate synthase
IGX36_RS08780	COG1346	cytolysis
IGX36_RS08790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGX36_RS08800	COG1538	Outer membrane efflux protein
IGX36_RS08805	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS08810	COG0586	Pfam SNARE associated Golgi protein
IGX36_RS08820	COG1686	Belongs to the peptidase S11 family
IGX36_RS08825	COG0277	FAD linked oxidase domain protein
IGX36_RS08830	COG1472	Belongs to the glycosyl hydrolase 3 family
IGX36_RS08835	COG1732	Glycine betaine
IGX36_RS08840	COG1174	glycine betaine transport
IGX36_RS08845	COG1125	glycine betaine transport
IGX36_RS08850	COG1174	glycine betaine transport
IGX36_RS08860	COG0789	Transcriptional regulator
IGX36_RS08865	COG3275	phosphorelay sensor kinase activity
IGX36_RS08870	COG3279	Response regulator of the LytR AlgR family
IGX36_RS08875	COG4807	Protein conserved in bacteria
IGX36_RS08880	COG4808	Protein conserved in bacteria
IGX36_RS08885	COG4715	Zinc finger, swim domain protein
IGX36_RS08890	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IGX36_RS08900	COG0714	Associated with various cellular activities
IGX36_RS08910	COG3831	ATPase activity
IGX36_RS08925	COG0489	protein tyrosine kinase activity
IGX36_RS08935	COG3539	Fimbrial protein
IGX36_RS08940	COG3121	Chaperone
IGX36_RS08945	COG3188	usher protein
IGX36_RS08950	COG3539	Fimbrial protein
IGX36_RS08955	COG5455	response to cobalt ion
IGX36_RS09020	COG0351	phosphomethylpyrimidine kinase
IGX36_RS09025	COG3757	hydrolase, family 25
IGX36_RS09030	COG2188	Transcriptional regulator
IGX36_RS09035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGX36_RS09040	COG1397	ADP-ribosylglycohydrolase
IGX36_RS09045	COG2211	Major facilitator Superfamily
IGX36_RS09050	COG1830	Aldolase
IGX36_RS09060	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
IGX36_RS09065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS09070	COG3414	Phosphotransferase system galactitol-specific IIB component
IGX36_RS09075	COG3775	system Galactitol-specific IIC component
IGX36_RS09080	COG1063	alcohol dehydrogenase
IGX36_RS09100	COG0826	peptidase U32
IGX36_RS09110	COG0745	RESPONSE REGULATOR receiver
IGX36_RS09115	COG2205	protein histidine kinase activity
IGX36_RS09155	COG4245	von Willebrand factor, type A
IGX36_RS09160	COG0631	protein serine/threonine phosphatase activity
IGX36_RS09165	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
IGX36_RS09170	COG0443	Heat shock 70 kDa protein
IGX36_RS09175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IGX36_RS09180	COG3447	MASE1 domain protein
IGX36_RS09180	COG5001	Diguanylate cyclase
IGX36_RS09180	COG5002	protein histidine kinase activity
IGX36_RS09185	COG0572	uridine kinase
IGX36_RS09195	COG2982	Protein involved in outer membrane biogenesis
IGX36_RS09200	COG1253	flavin adenine dinucleotide binding
IGX36_RS09210	COG1596	polysaccharide export
IGX36_RS09215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IGX36_RS09220	COG0489	protein tyrosine kinase activity
IGX36_RS09220	COG3206	protein involved in exopolysaccharide biosynthesis
IGX36_RS09225	COG0463	Glycosyl transferase, family 2
IGX36_RS09230	COG1045	serine acetyltransferase
IGX36_RS09235	COG0438	transferase activity, transferring glycosyl groups
IGX36_RS09245	COG1216	Glycosyl transferase, family 2
IGX36_RS09250	COG0110	maltose O-acetyltransferase activity
IGX36_RS09255	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IGX36_RS09260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IGX36_RS09265	COG1051	belongs to the nudix hydrolase family
IGX36_RS09270	COG0297	glycogen (starch) synthase activity
IGX36_RS09275	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IGX36_RS09275	COG0662	Cupin 2, conserved barrel domain protein
IGX36_RS09280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IGX36_RS09285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IGX36_RS09290	COG2244	polysaccharide biosynthetic process
IGX36_RS09295	COG2327	Polysaccharide pyruvyl transferase
IGX36_RS09300	COG0438	transferase activity, transferring glycosyl groups
IGX36_RS09310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IGX36_RS09315	COG1088	dTDP-glucose 4,6-dehydratase activity
IGX36_RS09385	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IGX36_RS09405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IGX36_RS09410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IGX36_RS09410	COG0131	Imidazoleglycerol-phosphate dehydratase
IGX36_RS09435	COG2161	toxin-antitoxin pair type II binding
IGX36_RS09445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IGX36_RS09450	COG0583	DNA-binding transcription factor activity
IGX36_RS09460	COG0531	amino acid
IGX36_RS09470	COG2925	Exonuclease
IGX36_RS09475	COG1686	Belongs to the peptidase S11 family
IGX36_RS09485	COG1289	transmembrane transporter activity
IGX36_RS09515	COG1454	alcohol dehydrogenase
IGX36_RS09515	COG1012	belongs to the aldehyde dehydrogenase family
IGX36_RS09530	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IGX36_RS09545	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IGX36_RS09605	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
IGX36_RS09620	COG1376	ErfK ybiS ycfS ynhG family protein
IGX36_RS09630	COG0583	DNA-binding transcription factor activity
IGX36_RS09635	COG0583	DNA-binding transcription factor activity
IGX36_RS09645	COG0534	Mate efflux family protein
IGX36_RS09670	COG3423	Transcriptional regulator
IGX36_RS09680	COG3209	COG3209 Rhs family protein
IGX36_RS09690	COG0217	transcriptional regulatory protein
IGX36_RS09695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IGX36_RS09750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IGX36_RS09830	COG1403	HNH endonuclease
IGX36_RS09835	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IGX36_RS09850	COG2207	Transcriptional regulator
IGX36_RS09900	COG3443	Belongs to the bacterial solute-binding protein 9 family
IGX36_RS09915	COG2351	hydroxyisourate hydrolase activity
IGX36_RS09920	COG0745	RESPONSE REGULATOR receiver
IGX36_RS09925	COG2205	protein histidine kinase activity
IGX36_RS09940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IGX36_RS09950	COG1418	mRNA catabolic process
IGX36_RS09955	COG0270	DNA (cytosine-5-)-methyltransferase activity
IGX36_RS09960	COG3727	T/G mismatch-specific endonuclease activity
IGX36_RS09965	COG0697	spore germination
IGX36_RS09970	COG2354	Protein conserved in bacteria
IGX36_RS09975	COG5475	Uncharacterized small protein (DUF2158)
IGX36_RS10000	COG2197	response regulator
IGX36_RS10005	COG1684	flagellar biosynthetic protein fliR
IGX36_RS10010	COG1987	bacterial-type flagellum assembly
IGX36_RS10015	COG1338	Plays a role in the flagellum-specific transport system
IGX36_RS10020	COG3190	flagellar
IGX36_RS10025	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IGX36_RS10030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IGX36_RS10035	COG1580	Controls the rotational direction of flagella during chemotaxis
IGX36_RS10040	COG3144	bacterial-type flagellum assembly
IGX36_RS10045	COG2882	bacterial-type flagellum organization
IGX36_RS10050	COG1157	protein secretion by the type III secretion system
IGX36_RS10055	COG1317	bacterial-type flagellum organization
IGX36_RS10060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IGX36_RS10065	COG1766	The M ring may be actively involved in energy transduction
IGX36_RS10085	COG2135	peptidase activity
IGX36_RS10090	COG0425	Belongs to the sulfur carrier protein TusA family
IGX36_RS10095	COG2391	methyltransferase activity
IGX36_RS10105	COG0366	Alpha amylase catalytic
IGX36_RS10115	COG1516	flagellar protein fliS
IGX36_RS10120	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IGX36_RS10130	COG1191	sigma factor activity
IGX36_RS10140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGX36_RS10150	COG0765	amino acid transport
IGX36_RS10155	COG1126	abc transporter atp-binding protein
IGX36_RS10160	COG2197	response regulator
IGX36_RS10175	COG2197	response regulator
IGX36_RS10205	COG3318	Belongs to the UPF0149 family
IGX36_RS10205	COG3012	SEC-C Motif Domain Protein
IGX36_RS10210	COG0814	amino acid
IGX36_RS10220	COG1528	Iron-storage protein
IGX36_RS10240	COG1528	Iron-storage protein
IGX36_RS10255	COG1172	Belongs to the binding-protein-dependent transport system permease family
IGX36_RS10260	COG1877	trehalose-phosphatase activity
IGX36_RS10270	COG0589	response to stress
IGX36_RS10285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IGX36_RS10290	COG1360	Flagellar Motor Protein
IGX36_RS10295	COG2198	Histidine kinase
IGX36_RS10295	COG0643	Histidine kinase
IGX36_RS10300	COG0835	chemotaxis
IGX36_RS10305	COG0840	transmembrane signaling receptor activity
IGX36_RS10310	COG0840	transmembrane signaling receptor activity
IGX36_RS10315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IGX36_RS10325	COG0745	RESPONSE REGULATOR receiver
IGX36_RS10330	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IGX36_RS10335	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IGX36_RS10340	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IGX36_RS10355	COG3102	Protein conserved in bacteria
IGX36_RS10365	COG3005	denitrification pathway
IGX36_RS10370	COG0243	molybdopterin cofactor binding
IGX36_RS10385	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IGX36_RS10390	COG1801	Protein of unknown function DUF72
IGX36_RS10395	COG1335	isochorismatase
IGX36_RS10405	COG0494	nUDIX hydrolase
IGX36_RS10410	COG0217	transcriptional regulatory protein
IGX36_RS10440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IGX36_RS10450	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IGX36_RS10455	COG0739	heme binding
IGX36_RS10460	COG1560	Kdo2-lipid A biosynthetic process
IGX36_RS10465	COG0469	pyruvate kinase activity
IGX36_RS10470	COG1737	Transcriptional regulator
IGX36_RS10475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IGX36_RS10480	COG0129	dihydroxy-acid dehydratase activity
IGX36_RS10485	COG0800	Aldolase
IGX36_RS10495	COG3141	response to X-ray
IGX36_RS10505	COG2979	Protein of unknown function (DUF533)
IGX36_RS10525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IGX36_RS10530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IGX36_RS10540	COG2372	response to copper ion
IGX36_RS10545	COG1276	copper resistance
IGX36_RS10555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IGX36_RS10575	COG3008	intermembrane lipid transfer
IGX36_RS10580	COG2995	paraquat-inducible protein a
IGX36_RS10585	COG1956	GAF domain-containing protein
IGX36_RS10595	COG0793	Belongs to the peptidase S41A family
IGX36_RS10605	COG2814	Major facilitator Superfamily
IGX36_RS10610	COG1414	Transcriptional regulator
IGX36_RS10640	COG2226	methyltransferase
IGX36_RS10655	COG3716	PTS system mannose fructose sorbose family IID component
IGX36_RS10660	COG3715	PTS system
IGX36_RS10665	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGX36_RS10665	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS10670	COG1253	flavin adenine dinucleotide binding
IGX36_RS10675	COG2200	EAL domain
IGX36_RS10680	COG1760	l-serine dehydratase
IGX36_RS10690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IGX36_RS10705	COG0251	oxidation-reduction process
IGX36_RS10710	COG1199	ATP-dependent helicase activity
IGX36_RS10715	COG1214	PFAM Peptidase M22, glycoprotease
IGX36_RS10720	COG3065	identical protein binding
IGX36_RS10725	COG0318	PFAM AMP-dependent synthetase and ligase
IGX36_RS10730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IGX36_RS10735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IGX36_RS10740	COG4638	Rieske (2fe-2S)
IGX36_RS10745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IGX36_RS10750	COG0473	3-isopropylmalate dehydrogenase activity
IGX36_RS10775	COG2261	transglycosylase associated protein
IGX36_RS10790	COG2199	diguanylate cyclase activity
IGX36_RS10790	COG2203	Gaf domain
IGX36_RS10795	COG3042	response to heat
IGX36_RS10800	COG3189	MarR family transcriptional regulator
IGX36_RS10805	COG2807	transmembrane transport
IGX36_RS10810	COG2207	Transcriptional regulator
IGX36_RS10830	COG2199	diguanylate cyclase activity
IGX36_RS10835	COG2199	diguanylate cyclase activity
IGX36_RS10845	COG2766	serine protein kinase
IGX36_RS10850	COG3713	MltA-interacting MipA family protein
IGX36_RS10855	COG0656	L-ascorbic acid biosynthetic process
IGX36_RS10860	COG0676	glucose-6-phosphate 1-epimerase activity
IGX36_RS10865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IGX36_RS10875	COG3139	Protein of unknown function (DUF1315)
IGX36_RS10880	COG1063	alcohol dehydrogenase
IGX36_RS10885	COG2271	Major facilitator Superfamily
IGX36_RS10890	COG1063	alcohol dehydrogenase
IGX36_RS10895	COG0191	fructose-bisphosphate aldolase activity
IGX36_RS10900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGX36_RS10905	COG0667	Aldo Keto reductase
IGX36_RS10910	COG1349	DNA-binding transcription factor activity
IGX36_RS10920	COG1335	isochorismatase
IGX36_RS10930	COG0616	signal peptide processing
IGX36_RS10935	COG0778	Nitroreductase
IGX36_RS10945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IGX36_RS10955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IGX36_RS10965	COG0494	nUDIX hydrolase
IGX36_RS10970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IGX36_RS10975	COG2897	thiosulfate sulfurtransferase activity
IGX36_RS10980	COG4136	ATPase activity
IGX36_RS10985	COG4135	transport system, permease component
IGX36_RS10990	COG4134	Bacterial extracellular solute-binding protein
IGX36_RS10995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IGX36_RS11000	COG0398	Pfam SNARE associated Golgi protein
IGX36_RS11010	COG0398	Pfam SNARE associated Golgi protein
IGX36_RS11015	COG0708	Exodeoxyribonuclease III
IGX36_RS11045	COG3678	ATP-independent chaperone mediated protein folding
IGX36_RS11055	COG0322	excinuclease ABC activity
IGX36_RS11065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IGX36_RS11070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IGX36_RS11075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IGX36_RS11080	COG1447	Phosphotransferase system cellobiose-specific component IIA
IGX36_RS11085	COG2169	Transcriptional regulator
IGX36_RS11085	COG1917	Cupin 2, conserved barrel domain protein
IGX36_RS11090	COG1486	melibiose metabolic process
IGX36_RS11100	COG0753	catalase activity
IGX36_RS11115	COG1823	symporter activity
IGX36_RS11120	COG1988	membrane-bound metal-dependent
IGX36_RS11135	COG3001	Fructosamine kinase
IGX36_RS11145	COG1105	Belongs to the carbohydrate kinase PfkB family
IGX36_RS11150	COG3137	Salt-induced outer membrane protein
IGX36_RS11240	COG4372	Transposase
IGX36_RS11245	COG3436	PFAM IS66 Orf2 family protein
IGX36_RS11280	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IGX36_RS11305	COG4974	Belongs to the 'phage' integrase family
IGX36_RS11325	COG0386	Belongs to the glutathione peroxidase family
IGX36_RS11335	COG0791	NLP P60 protein
IGX36_RS11350	COG4256	Hemin uptake protein
IGX36_RS11355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IGX36_RS11365	COG0574	Belongs to the PEP-utilizing enzyme family
IGX36_RS11365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGX36_RS11370	COG0318	PFAM AMP-dependent synthetase and ligase
IGX36_RS11375	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IGX36_RS11380	COG0644	oxidoreductase
IGX36_RS11385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IGX36_RS11390	COG2086	electron transfer activity
IGX36_RS11395	COG1917	Cupin 2, conserved barrel domain protein
IGX36_RS11395	COG2207	Transcriptional regulator
IGX36_RS11400	COG1960	acyl-CoA dehydrogenase activity
IGX36_RS11405	COG4670	ketone body catabolic process
IGX36_RS11420	COG2271	Major facilitator Superfamily
IGX36_RS11425	COG0738	Major facilitator superfamily
IGX36_RS11440	COG0628	permease
IGX36_RS11445	COG0247	lactate metabolic process
IGX36_RS11445	COG0277	FAD linked oxidase domain protein
IGX36_RS11450	COG2050	protein possibly involved in aromatic compounds catabolism
IGX36_RS11460	COG0316	Belongs to the HesB IscA family
IGX36_RS11465	COG0719	Fe-S assembly protein
IGX36_RS11470	COG0396	ATPase activity
IGX36_RS11475	COG0719	Fe-S assembly protein
IGX36_RS11490	COG1376	ErfK ybiS ycfS ynhG family protein
IGX36_RS11495	COG4238	major outer membrane lipoprotein
IGX36_RS11500	COG0469	pyruvate kinase activity
IGX36_RS11510	COG0437	4 iron, 4 sulfur cluster binding
IGX36_RS11515	COG2414	aldehyde ferredoxin oxidoreductase
IGX36_RS11525	COG0437	4 iron, 4 sulfur cluster binding
IGX36_RS11530	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IGX36_RS11560	COG3468	outer membrane autotransporter barrel domain protein
IGX36_RS11570	COG0307	riboflavin synthase, alpha
IGX36_RS11575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IGX36_RS11580	COG2814	Major facilitator Superfamily
IGX36_RS11585	COG0583	DNA-binding transcription factor activity
IGX36_RS11600	COG2814	Major facilitator Superfamily
IGX36_RS11605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IGX36_RS11610	COG0791	NLP P60 protein
IGX36_RS11615	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IGX36_RS11620	COG1201	RNA secondary structure unwinding
IGX36_RS11630	COG0346	lactoylglutathione lyase activity
IGX36_RS11635	COG1902	pentaerythritol trinitrate reductase activity
IGX36_RS11640	COG1309	transcriptional regulator
IGX36_RS11645	COG3313	Fe-S protein
IGX36_RS11650	COG4989	oxidoreductase activity
IGX36_RS11655	COG2032	superoxide dismutase activity
IGX36_RS11660	COG1289	transmembrane transporter activity
IGX36_RS11665	COG1566	PFAM secretion protein HlyD family protein
IGX36_RS11680	COG3133	Outer membrane lipoprotein
IGX36_RS11690	COG3895	Periplasmic Protein
IGX36_RS11710	COG0625	glutathione transferase activity
IGX36_RS11715	COG3104	oligopeptide transport
IGX36_RS11720	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IGX36_RS11730	COG4659	FMN binding
IGX36_RS11735	COG4658	electron transport chain
IGX36_RS11770	COG0673	inositol 2-dehydrogenase activity
IGX36_RS11780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IGX36_RS11785	COG1263	PTS System
IGX36_RS11785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGX36_RS11790	COG1609	Transcriptional regulator
IGX36_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS11800	COG1309	transcriptional regulator
IGX36_RS11805	COG3250	beta-galactosidase activity
IGX36_RS11820	COG5339	Protein conserved in bacteria
IGX36_RS11825	COG1482	cell wall glycoprotein biosynthetic process
IGX36_RS11830	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IGX36_RS11830	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IGX36_RS11835	COG0114	fumarate hydratase activity
IGX36_RS11850	COG0745	RESPONSE REGULATOR receiver
IGX36_RS11855	COG3136	membrane protein required for alginate biosynthesis
IGX36_RS11865	COG0531	amino acid
IGX36_RS11875	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IGX36_RS11880	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IGX36_RS11885	COG0628	permease
IGX36_RS11900	COG3591	Belongs to the peptidase S1B family
IGX36_RS11915	COG2814	Major facilitator Superfamily
IGX36_RS11920	COG0583	DNA-binding transcription factor activity
IGX36_RS11925	COG1940	carbohydrate kinase activity
IGX36_RS11930	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IGX36_RS11940	COG3381	protein complex oligomerization
IGX36_RS11945	COG3302	dmso reductase anchor subunit
IGX36_RS11950	COG0437	4 iron, 4 sulfur cluster binding
IGX36_RS11960	COG0243	molybdopterin cofactor binding
IGX36_RS11975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IGX36_RS11990	COG4948	Mandelate Racemase Muconate Lactonizing
IGX36_RS11995	COG1063	alcohol dehydrogenase
IGX36_RS12005	COG0582	viral genome integration into host DNA
IGX36_RS12015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IGX36_RS12040	COG1396	sequence-specific DNA binding
IGX36_RS12070	COG2801	Transposase and inactivated derivatives
IGX36_RS12085	COG3077	Addiction module antitoxin, RelB DinJ family
IGX36_RS12090	COG2026	Addiction module toxin, RelE StbE family
IGX36_RS12110	COG1403	HNH endonuclease
IGX36_RS12115	COG0484	heat shock protein binding
IGX36_RS12125	COG1278	Cold shock
IGX36_RS12130	COG1278	Cold shock
IGX36_RS12145	COG3772	lysozyme
IGX36_RS12155	COG1278	Cold shock
IGX36_RS12180	COG5562	phage envelope protein
IGX36_RS12190	COG4220	transposase activity
IGX36_RS12205	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IGX36_RS12210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IGX36_RS12230	COG0246	Mannitol dehydrogenase
IGX36_RS12240	COG1802	Transcriptional regulator
IGX36_RS12245	COG4221	oxidoreductase activity
IGX36_RS12250	COG0339	signal peptide processing
IGX36_RS12255	COG3111	PFAM Bacterial OB fold (BOF) protein
IGX36_RS12260	COG3706	GGDEF domain
IGX36_RS12270	COG2814	Major facilitator Superfamily
IGX36_RS12275	COG0697	spore germination
IGX36_RS12280	COG2188	Transcriptional regulator
IGX36_RS12290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IGX36_RS12295	COG1447	Phosphotransferase system cellobiose-specific component IIA
IGX36_RS12305	COG2723	6-phospho-beta-galactosidase activity
IGX36_RS12315	COG4977	sequence-specific DNA binding
IGX36_RS12340	COG0583	DNA-binding transcription factor activity
IGX36_RS12345	COG1012	belongs to the aldehyde dehydrogenase family
IGX36_RS12350	COG2066	Belongs to the glutaminase family
IGX36_RS12360	COG2199	diguanylate cyclase activity
IGX36_RS12370	COG3781	membrane
IGX36_RS12440	COG1396	sequence-specific DNA binding
IGX36_RS12445	COG3550	peptidyl-serine autophosphorylation
IGX36_RS12465	COG0656	L-ascorbic acid biosynthetic process
IGX36_RS12485	COG2249	NAD(P)H dehydrogenase (quinone) activity
IGX36_RS12490	COG0667	Aldo Keto reductase
IGX36_RS12510	COG3539	Fimbrial protein
IGX36_RS12520	COG3188	usher protein
IGX36_RS12525	COG3188	usher protein
IGX36_RS12530	COG3539	Fimbrial protein
IGX36_RS12535	COG3539	Fimbrial protein
IGX36_RS12540	COG3539	Fimbrial protein
IGX36_RS12545	COG0243	molybdopterin cofactor binding
IGX36_RS12560	COG3119	arylsulfatase activity
IGX36_RS12575	COG4178	(ABC) transporter
IGX36_RS12590	COG4771	TonB-dependent receptor
IGX36_RS12595	COG0612	Peptidase, M16
IGX36_RS12600	COG0076	glutamate decarboxylase activity
IGX36_RS12605	COG0531	amino acid
IGX36_RS12610	COG1649	PFAM Uncharacterised BCR, COG1649
IGX36_RS12625	COG2200	EAL domain
IGX36_RS12625	COG2202	Pas domain
IGX36_RS12625	COG2199	diguanylate cyclase activity
IGX36_RS12630	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IGX36_RS12635	COG0747	negative chemotaxis
IGX36_RS12640	COG0601	transmembrane transport
IGX36_RS12645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGX36_RS12650	COG0444	Belongs to the ABC transporter superfamily
IGX36_RS12655	COG4608	Belongs to the ABC transporter superfamily
IGX36_RS12660	COG1764	response to oxidative stress
IGX36_RS12680	COG1064	alcohol dehydrogenase
IGX36_RS12685	COG3093	addiction module antidote protein HigA
IGX36_RS12690	COG2864	formate dehydrogenase
IGX36_RS12705	COG0697	spore germination
IGX36_RS12725	COG2223	nitrite transmembrane transporter activity
IGX36_RS12755	COG0826	peptidase U32
IGX36_RS12760	COG1396	sequence-specific DNA binding
IGX36_RS12775	COG0500	methyltransferase
IGX36_RS12780	COG1275	C4-dicarboxylate transporter malic acid transport protein
IGX36_RS12785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IGX36_RS12790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IGX36_RS12795	COG2841	Protein conserved in bacteria
IGX36_RS12805	COG5383	Protein conserved in bacteria
IGX36_RS12810	COG0583	DNA-binding transcription factor activity
IGX36_RS12815	COG0840	transmembrane signaling receptor activity
IGX36_RS12830	COG3038	cytochrome b561
IGX36_RS12835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IGX36_RS12840	COG1012	belongs to the aldehyde dehydrogenase family
IGX36_RS12850	COG1643	Atp-dependent helicase
IGX36_RS12865	COG2267	carboxylic ester hydrolase activity
IGX36_RS12870	COG4589	Belongs to the CDS family
IGX36_RS12875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IGX36_RS12885	COG0667	Aldo Keto reductase
IGX36_RS12890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IGX36_RS12895	COG3327	negative regulation of DNA-templated transcription, initiation
IGX36_RS12900	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IGX36_RS12905	COG0183	Belongs to the thiolase family
IGX36_RS12910	COG2050	protein possibly involved in aromatic compounds catabolism
IGX36_RS12915	COG1250	3-hydroxyacyl-CoA dehydrogenase
IGX36_RS12920	COG1024	Enoyl-CoA hydratase
IGX36_RS12925	COG1024	Enoyl-CoA hydratase
IGX36_RS12930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IGX36_RS12935	COG2151	metal-sulfur cluster biosynthetic enzyme
IGX36_RS12940	COG3396	Phenylacetate-CoA oxygenase
IGX36_RS12945	COG3460	Phenylacetate-CoA oxygenase
IGX36_RS12950	COG3396	Phenylacetate-CoA oxygenase
IGX36_RS12955	COG1012	belongs to the aldehyde dehydrogenase family
IGX36_RS12955	COG2030	dehydratase
IGX36_RS12960	COG3733	amine oxidase
IGX36_RS12965	COG1012	belongs to the aldehyde dehydrogenase family
IGX36_RS12970	COG2207	Transcriptional regulator
IGX36_RS12975	COG3784	Protein of unknown function (DUF1318)
IGX36_RS12985	COG2911	Protein conserved in bacteria
IGX36_RS12990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGX36_RS12995	COG3187	Heat shock protein
IGX36_RS13000	COG3042	response to heat
IGX36_RS13005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IGX36_RS13005	COG1013	pyruvate-flavodoxin oxidoreductase activity
IGX36_RS13005	COG0674	pyruvate-flavodoxin oxidoreductase activity
IGX36_RS13005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IGX36_RS13020	COG0589	response to stress
IGX36_RS13030	COG0513	Belongs to the DEAD box helicase family
IGX36_RS13040	COG3706	GGDEF domain
IGX36_RS13045	COG2840	Smr protein MutS2
IGX36_RS13060	COG2207	Transcriptional regulator
IGX36_RS13065	COG0583	DNA-binding transcription factor activity
IGX36_RS13070	COG1473	amidohydrolase
IGX36_RS13075	COG1473	amidohydrolase
IGX36_RS13080	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IGX36_RS13085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IGX36_RS13090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IGX36_RS13095	COG0589	response to stress
IGX36_RS13100	COG3182	Iron-regulated membrane protein
IGX36_RS13105	COG0668	transmembrane transport
IGX36_RS13110	COG4166	transmembrane transport
IGX36_RS13115	COG0583	DNA-binding transcription factor activity
IGX36_RS13120	COG1073	alpha beta
IGX36_RS13140	COG2866	Carboxypeptidase
IGX36_RS13145	COG4948	Mandelate Racemase Muconate Lactonizing
IGX36_RS13150	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IGX36_RS13155	COG3283	Transcriptional regulator of aromatic amino acids metabolism
IGX36_RS13165	COG3106	COG3106 Predicted ATPase
IGX36_RS13180	COG3842	ATPase activity
IGX36_RS13185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IGX36_RS13190	COG1554	hydrolase, family 65, central catalytic
IGX36_RS13195	COG0673	inositol 2-dehydrogenase activity
IGX36_RS13200	COG1082	Xylose isomerase domain protein TIM barrel
IGX36_RS13205	COG1063	alcohol dehydrogenase
IGX36_RS13210	COG0395	ABC-type sugar transport system, permease component
IGX36_RS13215	COG1175	transmembrane transport
IGX36_RS13220	COG1653	transport
IGX36_RS13230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IGX36_RS13240	COG1983	PspC domain protein
IGX36_RS13250	COG1842	Phage shock protein A
IGX36_RS13255	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IGX36_RS13260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IGX36_RS13265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IGX36_RS13270	COG1012	belongs to the aldehyde dehydrogenase family
IGX36_RS13275	COG1917	Cupin 2, conserved barrel domain protein
IGX36_RS13275	COG1396	sequence-specific DNA binding
IGX36_RS13280	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IGX36_RS13285	COG0174	glutamine synthetase
IGX36_RS13295	COG0531	amino acid
IGX36_RS13305	COG4166	transmembrane transport
IGX36_RS13310	COG4168	peptide transport system, permease
IGX36_RS13315	COG4171	peptide transport system, permease
IGX36_RS13320	COG4172	Belongs to the ABC transporter superfamily
IGX36_RS13325	COG4172	Belongs to the ABC transporter superfamily
IGX36_RS13330	COG2814	Major facilitator Superfamily
IGX36_RS13340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IGX36_RS13345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGX36_RS13355	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IGX36_RS13360	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IGX36_RS13360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IGX36_RS13375	COG5001	Diguanylate cyclase
IGX36_RS13385	COG1349	DNA-binding transcription factor activity
IGX36_RS13395	COG0023	Translation Initiation Factor
IGX36_RS13405	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IGX36_RS13410	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IGX36_RS13415	COG0671	phosphoesterase, PA-phosphatase related
IGX36_RS13425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IGX36_RS13445	COG0583	DNA-binding transcription factor activity
IGX36_RS13450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IGX36_RS13460	COG0616	signal peptide processing
IGX36_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS13470	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IGX36_RS13485	COG1187	pseudouridine synthase activity
IGX36_RS13490	COG4907	membrane protein (DUF2207)
IGX36_RS13495	COG0009	L-threonylcarbamoyladenylate synthase
IGX36_RS13500	COG0613	PHP domain protein
IGX36_RS13510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IGX36_RS13515	COG0512	Glutamine amidotransferase of anthranilate synthase
IGX36_RS13515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IGX36_RS13520	COG0135	phosphoribosylanthranilate isomerase activity
IGX36_RS13520	COG0134	indole-3-glycerol-phosphate synthase activity
IGX36_RS13535	COG3729	General stress protein
IGX36_RS13540	COG3685	Protein conserved in bacteria
IGX36_RS13545	COG3685	Protein conserved in bacteria
IGX36_RS13625	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IGX36_RS13630	COG1403	HNH endonuclease
IGX36_RS13665	COG1846	Transcriptional regulator
IGX36_RS13680	COG1396	sequence-specific DNA binding
IGX36_RS13710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IGX36_RS13720	COG0582	viral genome integration into host DNA
IGX36_RS13725	COG3047	cAMP biosynthetic process
IGX36_RS13745	COG1607	acyl-coa hydrolase
IGX36_RS13750	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IGX36_RS13755	COG2350	Protein conserved in bacteria
IGX36_RS13760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IGX36_RS13780	COG4608	Belongs to the ABC transporter superfamily
IGX36_RS13785	COG0444	Belongs to the ABC transporter superfamily
IGX36_RS13790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGX36_RS13795	COG0601	transmembrane transport
IGX36_RS13800	COG4166	transmembrane transport
IGX36_RS13805	COG2095	MarC family integral membrane protein
IGX36_RS13810	COG1012	belongs to the aldehyde dehydrogenase family
IGX36_RS13810	COG1454	alcohol dehydrogenase
IGX36_RS13815	COG1435	thymidine kinase activity
IGX36_RS13830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IGX36_RS13835	COG0745	RESPONSE REGULATOR receiver
IGX36_RS13875	COG2181	nitrate reductase activity
IGX36_RS13880	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IGX36_RS13885	COG1140	nitrate reductase beta subunit
IGX36_RS13890	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IGX36_RS13895	COG2223	nitrite transmembrane transporter activity
IGX36_RS13900	COG3850	Histidine kinase
IGX36_RS13905	COG2197	response regulator
IGX36_RS13910	COG4932	domain protein
IGX36_RS13915	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IGX36_RS13920	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IGX36_RS13925	COG4572	Cation transport regulator
IGX36_RS13930	COG0387	Pfam Sodium calcium exchanger
IGX36_RS13955	COG2912	Transglutaminase-like superfamily
IGX36_RS13960	COG3094	Invasion gene expression up-regulator, SirB
IGX36_RS13965	COG2890	protein-(glutamine-N5) methyltransferase activity
IGX36_RS13990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGX36_RS13995	COG0659	secondary active sulfate transmembrane transporter activity
IGX36_RS14010	COG0012	GTP binding
IGX36_RS14015	COG3468	outer membrane autotransporter barrel domain protein
IGX36_RS14020	COG3284	Transcriptional regulator
IGX36_RS14025	COG2376	Dihydroxyacetone kinase
IGX36_RS14030	COG1461	Dihydroxyacetone kinase
IGX36_RS14035	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IGX36_RS14035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGX36_RS14035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS14045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IGX36_RS14050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGX36_RS14055	COG1120	ATPase activity
IGX36_RS14060	COG0500	methyltransferase
IGX36_RS14065	COG0157	Belongs to the NadC ModD family
IGX36_RS14080	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IGX36_RS14090	COG1619	proteins homologs of microcin C7 resistance protein MccF
IGX36_RS14105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IGX36_RS14115	COG2719	SpoVR family
IGX36_RS14135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IGX36_RS14140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IGX36_RS14145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IGX36_RS14160	COG0179	Fumarylacetoacetate (FAA) hydrolase
IGX36_RS14185	COG2894	cell division
IGX36_RS14280	COG0789	Transcriptional regulator
IGX36_RS14285	COG5562	phage envelope protein
IGX36_RS14315	COG0538	isocitrate dehydrogenase activity
IGX36_RS14320	COG1187	pseudouridine synthase activity
IGX36_RS14340	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IGX36_RS14350	COG2205	protein histidine kinase activity
IGX36_RS14355	COG2850	peptidyl-arginine hydroxylation
IGX36_RS14365	COG3842	ATPase activity
IGX36_RS14375	COG1177	transmembrane transport
IGX36_RS14380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IGX36_RS14390	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IGX36_RS14395	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IGX36_RS14405	COG4591	ABC-type transport system involved in lipoprotein release permease component
IGX36_RS14415	COG4591	ABC-type transport system involved in lipoprotein release permease component
IGX36_RS14420	COG4763	Acyl-transferase
IGX36_RS14425	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IGX36_RS14430	COG1388	LysM domain
IGX36_RS14430	COG1376	ErfK ybiS ycfS ynhG family protein
IGX36_RS14440	COG1309	transcriptional regulator
IGX36_RS14445	COG3134	Outer membrane lipoprotein
IGX36_RS14450	COG1252	NADH dehydrogenase
IGX36_RS14470	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
IGX36_RS14475	COG5633	Lipoprotein
IGX36_RS14480	COG0537	adenosine 5'-monophosphoramidase activity
IGX36_RS14495	COG0084	hydrolase, TatD family'
IGX36_RS14500	COG0470	DNA polymerase III
IGX36_RS14510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IGX36_RS14515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IGX36_RS14520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IGX36_RS14530	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS14535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IGX36_RS14555	COG1399	metal-binding, possibly nucleic acid-binding protein
IGX36_RS14560	COG0424	maF-like protein
IGX36_RS14565	COG0564	pseudouridine synthase activity
IGX36_RS14570	COG1530	ribonuclease E activity
IGX36_RS14575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IGX36_RS14580	COG1256	bacterial-type flagellum assembly
IGX36_RS14585	COG1705	Flagellar rod assembly protein muramidase FlgJ
IGX36_RS14585	COG3951	Flagellar rod assembly protein muramidase FlgJ
IGX36_RS14600	COG4786	Flagellar basal body rod
IGX36_RS14605	COG4787	bacterial-type flagellum-dependent cell motility
IGX36_RS14610	COG1749	Flagellar hook protein flgE
IGX36_RS14615	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IGX36_RS14620	COG1558	bacterial-type flagellum-dependent cell motility
IGX36_RS14625	COG1815	bacterial-type flagellum-dependent cell motility
IGX36_RS14630	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IGX36_RS14635	COG2747	anti-sigma28 factor FlgM
IGX36_RS14640	COG3418	PFAM FlgN family protein
IGX36_RS14645	COG0728	peptidoglycan biosynthetic process
IGX36_RS14650	COG0673	inositol 2-dehydrogenase activity
IGX36_RS14660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IGX36_RS14670	COG2999	glutathione oxidoreductase activity
IGX36_RS14705	COG3038	cytochrome b561
IGX36_RS14710	COG2353	YceI-like domain
IGX36_RS14720	COG1560	Kdo2-lipid A biosynthetic process
IGX36_RS14735	COG5645	(Lipo)protein
IGX36_RS14740	COG2943	transferase activity, transferring hexosyl groups
IGX36_RS14755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGX36_RS14760	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IGX36_RS14785	COG2197	response regulator
IGX36_RS14800	COG1462	curli production assembly transport component CsgG
IGX36_RS14810	COG3381	protein complex oligomerization
IGX36_RS14880	COG3039	Transposase
IGX36_RS14905	COG3344	reverse transcriptase
IGX36_RS14915	COG2826	transposase and inactivated derivatives, IS30 family
IGX36_RS14990	COG0582	viral genome integration into host DNA
IGX36_RS14995	COG3706	GGDEF domain
IGX36_RS15000	COG0457	Tetratricopeptide repeat
IGX36_RS15005	COG1649	PFAM Uncharacterised BCR, COG1649
IGX36_RS15005	COG0726	polysaccharide deacetylase
IGX36_RS15015	COG3658	cytochrome
IGX36_RS15020	COG1702	phosphate starvation-inducible protein PhoH
IGX36_RS15030	COG2822	iron ion transport
IGX36_RS15040	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IGX36_RS15050	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IGX36_RS15050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IGX36_RS15050	COG0506	proline dehydrogenase activity
IGX36_RS15055	COG1309	transcriptional regulator
IGX36_RS15095	COG3729	General stress protein
IGX36_RS15135	COG0243	molybdopterin cofactor binding
IGX36_RS15140	COG3005	denitrification pathway
IGX36_RS15145	COG0745	RESPONSE REGULATOR receiver
IGX36_RS15150	COG1879	ABC-type sugar transport system periplasmic component
IGX36_RS15155	COG2205	protein histidine kinase activity
IGX36_RS15155	COG2198	Histidine kinase
IGX36_RS15155	COG0784	Response regulator, receiver
IGX36_RS15180	COG1278	Cold shock
IGX36_RS15185	COG1278	Cold shock
IGX36_RS15200	COG1294	oxidase, subunit
IGX36_RS15205	COG1271	oxidase subunit
IGX36_RS15210	COG1773	rubredoxin
IGX36_RS15215	COG1999	signal sequence binding
IGX36_RS15220	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IGX36_RS15225	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
IGX36_RS15230	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IGX36_RS15235	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IGX36_RS15250	COG5301	cellulose 1,4-beta-cellobiosidase activity
IGX36_RS15305	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IGX36_RS15310	COG1403	HNH endonuclease
IGX36_RS15360	COG1846	Transcriptional regulator
IGX36_RS15410	COG0670	Belongs to the BI1 family
IGX36_RS15415	COG2920	part of a sulfur-relay system
IGX36_RS15420	COG1254	Belongs to the acylphosphatase family
IGX36_RS15435	COG1832	CoA-binding protein
IGX36_RS15450	COG0210	DNA helicase
IGX36_RS15455	COG3304	Inner membrane component domain
IGX36_RS15460	COG1289	transmembrane transporter activity
IGX36_RS15465	COG3070	regulator of competence-specific genes
IGX36_RS15485	COG1067	ATP-dependent peptidase activity
IGX36_RS15495	COG3130	regulation of translation
IGX36_RS15500	COG3009	Protein conserved in bacteria
IGX36_RS15505	COG3008	intermembrane lipid transfer
IGX36_RS15505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IGX36_RS15510	COG2995	paraquat-inducible protein a
IGX36_RS15515	COG0488	(ABC) transporter
IGX36_RS15525	COG0633	Ferredoxin
IGX36_RS15525	COG3217	Mosc domain protein beta barrel domain protein
IGX36_RS15540	COG0431	NADPH-dependent FMN reductase
IGX36_RS15545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IGX36_RS15555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IGX36_RS15560	COG1116	anion transmembrane transporter activity
IGX36_RS15565	COG0308	aminopeptidase N
IGX36_RS15585	COG1448	Aminotransferase
IGX36_RS15590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IGX36_RS15595	COG3108	Peptidase M15
IGX36_RS15600	COG2989	Protein conserved in bacteria
IGX36_RS15610	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IGX36_RS15620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IGX36_RS15625	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IGX36_RS15630	COG3173	Aminoglycoside phosphotransferase
IGX36_RS15645	COG3214	Protein conserved in bacteria
IGX36_RS15660	COG0658	competence protein
IGX36_RS15660	COG2333	competence protein COMEC
IGX36_RS15670	COG0539	negative regulation of cytoplasmic translation
IGX36_RS15680	COG0501	Belongs to the peptidase M48B family
IGX36_RS15700	COG2323	membrane
IGX36_RS15705	COG1944	ATP diphosphatase activity
IGX36_RS15710	COG2116	formate transmembrane transporter activity
IGX36_RS15715	COG1882	Formate acetyltransferase
IGX36_RS15720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IGX36_RS15730	COG0531	amino acid
IGX36_RS15740	COG1335	isochorismatase
IGX36_RS15745	COG3302	dmso reductase anchor subunit
IGX36_RS15750	COG0437	4 iron, 4 sulfur cluster binding
IGX36_RS15755	COG0243	molybdopterin cofactor binding
IGX36_RS15765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IGX36_RS15775	COG1674	ftsk spoiiie
IGX36_RS15775	COG1178	ABC-type Fe3 transport system permease component
IGX36_RS15780	COG1522	sequence-specific DNA binding
IGX36_RS15785	COG0492	ferredoxin-NADP+ reductase activity
IGX36_RS15790	COG4988	ABC transporter
IGX36_RS15795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IGX36_RS15815	COG0542	response to heat
IGX36_RS15825	COG1278	Cold shock
IGX36_RS15830	COG1136	(ABC) transporter
IGX36_RS15830	COG0577	efflux transmembrane transporter activity
IGX36_RS15835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGX36_RS15840	COG2990	Protein conserved in bacteria
IGX36_RS15845	COG3593	DNA synthesis involved in DNA repair
IGX36_RS15850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IGX36_RS15855	COG2431	L-lysine efflux transmembrane transporter activity
IGX36_RS15865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IGX36_RS15870	COG0028	Belongs to the TPP enzyme family
IGX36_RS15875	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IGX36_RS15880	COG0702	epimerase
IGX36_RS15885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IGX36_RS15890	COG3023	N-Acetylmuramoyl-L-alanine amidase
IGX36_RS15910	COG1126	abc transporter atp-binding protein
IGX36_RS15915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGX36_RS15920	COG4215	(ABC) transporter
IGX36_RS15925	COG4160	amino acid transport
IGX36_RS15945	COG1177	transmembrane transport
IGX36_RS15950	COG1176	ABC-type spermidine putrescine transport system, permease component I
IGX36_RS15955	COG3842	ATPase activity
IGX36_RS15960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IGX36_RS15975	COG0778	Nitroreductase
IGX36_RS15985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IGX36_RS16080	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IGX36_RS16085	COG3226	Transcriptional regulator
IGX36_RS16090	COG0738	Major facilitator superfamily
IGX36_RS16105	COG2814	Major facilitator Superfamily
IGX36_RS16110	COG0671	phosphoesterase, PA-phosphatase related
IGX36_RS16115	COG1349	DNA-binding transcription factor activity
IGX36_RS16120	COG1686	Belongs to the peptidase S11 family
IGX36_RS16125	COG0625	glutathione transferase activity
IGX36_RS16130	COG2133	pyrroloquinoline quinone binding
IGX36_RS16155	COG2199	diguanylate cyclase activity
IGX36_RS16160	COG2200	EAL domain
IGX36_RS16175	COG0747	negative chemotaxis
IGX36_RS16185	COG1446	asparaginase
IGX36_RS16190	COG0303	'Molybdopterin
IGX36_RS16195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IGX36_RS16200	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IGX36_RS16205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IGX36_RS16210	COG1882	Formate acetyltransferase
IGX36_RS16215	COG0561	phosphatase activity
IGX36_RS16225	COG0488	(ABC) transporter
IGX36_RS16230	COG1376	ErfK ybiS ycfS ynhG family protein
IGX36_RS16235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IGX36_RS16240	COG1321	iron dependent repressor
IGX36_RS16250	COG2194	sulfuric ester hydrolase activity
IGX36_RS16255	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IGX36_RS16265	COG5006	permease, DMT superfamily
IGX36_RS16275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGX36_RS16280	COG0765	amino acid transport
IGX36_RS16285	COG1126	abc transporter atp-binding protein
IGX36_RS16290	COG0668	transmembrane transport
IGX36_RS16305	COG4774	siderophore transport
IGX36_RS16315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IGX36_RS16325	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IGX36_RS16330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IGX36_RS16335	COG1199	ATP-dependent helicase activity
IGX36_RS16355	COG0513	Belongs to the DEAD box helicase family
IGX36_RS16360	COG1309	transcriptional regulator
IGX36_RS16370	COG1131	(ABC) transporter
IGX36_RS16375	COG0842	Transport permease protein
IGX36_RS16380	COG0842	Transport permease protein
IGX36_RS16390	COG3568	Endonuclease Exonuclease Phosphatase
IGX36_RS16395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGX36_RS16400	COG0392	lysyltransferase activity
IGX36_RS16405	COG0670	Belongs to the BI1 family
IGX36_RS16410	COG0670	Belongs to the BI1 family
IGX36_RS16415	COG0314	molybdopterin synthase activity
IGX36_RS16420	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IGX36_RS16430	COG0521	Mo-molybdopterin cofactor biosynthetic process
IGX36_RS16440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IGX36_RS16450	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IGX36_RS16455	COG2226	methyltransferase
IGX36_RS16470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IGX36_RS16475	COG1881	PFAM PEBP family protein
IGX36_RS16565	COG3723	Recombinational DNA repair protein, rece pathway
IGX36_RS16600	COG0582	viral genome integration into host DNA
IGX36_RS16605	COG4677	pectinesterase activity
IGX36_RS16610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IGX36_RS16615	COG0471	metal ion transport
IGX36_RS16620	COG2828	Protein conserved in bacteria
IGX36_RS16625	COG0583	DNA-binding transcription factor activity
IGX36_RS16635	COG0561	phosphatase activity
IGX36_RS16640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IGX36_RS16645	COG4149	molybdate abc transporter
IGX36_RS16650	COG0725	ABC transporter, periplasmic molybdate-binding protein
IGX36_RS16660	COG2005	Transcriptional regulator
IGX36_RS16660	COG3585	molybdate ion transport
IGX36_RS16665	COG1119	ATPase activity
IGX36_RS16670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IGX36_RS16675	COG1085	galactose-1-phosphate uridylyltransferase
IGX36_RS16685	COG2017	converts alpha-aldose to the beta-anomer
IGX36_RS16695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IGX36_RS16705	COG1230	cation diffusion facilitator family transporter
IGX36_RS16710	COG3201	nicotinamide mononucleotide transporter
IGX36_RS16750	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IGX36_RS16755	COG2885	chlorophyll binding
IGX36_RS16765	COG3064	Membrane
IGX36_RS16770	COG0848	biopolymer transport protein
IGX36_RS16775	COG0811	peptide transport
IGX36_RS16780	COG0824	Thioesterase
IGX36_RS16785	COG3790	cyd operon protein YbgE
IGX36_RS16790	COG4890	Cyd operon protein YbgT
IGX36_RS16795	COG1294	oxidase, subunit
IGX36_RS16800	COG1271	oxidase subunit
IGX36_RS16815	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IGX36_RS16825	COG4865	methylaspartate mutase activity
IGX36_RS16830	COG3799	methylaspartate ammonia-lyase activity
IGX36_RS16845	COG1301	dicarboxylic acid transport
IGX36_RS16850	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IGX36_RS16850	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IGX36_RS16855	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IGX36_RS16860	COG0583	DNA-binding transcription factor activity
IGX36_RS16865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IGX36_RS16875	COG0508	dehydrogenase complex catalyzes the overall conversion of
IGX36_RS16880	COG0567	Dehydrogenase, E1 component
IGX36_RS16885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IGX36_RS16890	COG1053	succinate dehydrogenase
IGX36_RS16895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IGX36_RS16900	COG2009	succinate dehydrogenase
IGX36_RS16910	COG0372	Belongs to the citrate synthase family
IGX36_RS16915	COG3539	Fimbrial protein
IGX36_RS16925	COG3121	Chaperone
IGX36_RS16940	COG3180	Ammonia monooxygenase
IGX36_RS16955	COG1984	allophanate hydrolase subunit 2
IGX36_RS16960	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IGX36_RS16965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IGX36_RS16975	COG0415	Belongs to the DNA photolyase family
IGX36_RS16980	COG3272	Protein of unknown function (DUF1722)
IGX36_RS17030	COG3209	COG3209 Rhs family protein
IGX36_RS17060	COG2205	protein histidine kinase activity
IGX36_RS17070	COG0033	Phosphoglucomutase
IGX36_RS17075	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IGX36_RS17080	COG0596	Alpha beta hydrolase
IGX36_RS17090	COG0716	FMN binding
IGX36_RS17100	COG0735	belongs to the Fur family
IGX36_RS17125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGX36_RS17125	COG2190	(PTS) system
IGX36_RS17125	COG1263	PTS System
IGX36_RS17135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IGX36_RS17140	COG1940	carbohydrate kinase activity
IGX36_RS17140	COG1846	Transcriptional regulator
IGX36_RS17145	COG0647	UMP catabolic process
IGX36_RS17150	COG0367	asparagine synthase
IGX36_RS17185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IGX36_RS17195	COG1702	phosphate starvation-inducible protein PhoH
IGX36_RS17205	COG4535	Mg2 and Co2 transporter CorC
IGX36_RS17210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IGX36_RS17215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IGX36_RS17220	COG0765	amino acid transport
IGX36_RS17225	COG0765	amino acid transport
IGX36_RS17230	COG1126	abc transporter atp-binding protein
IGX36_RS17240	COG2888	peptidyl-tyrosine sulfation
IGX36_RS17255	COG1466	dna polymerase III delta subunit
IGX36_RS17270	COG0799	negative regulation of ribosome biogenesis
IGX36_RS17280	COG0768	penicillin binding
IGX36_RS17285	COG0772	Belongs to the SEDS family
IGX36_RS17290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IGX36_RS17295	COG1686	Belongs to the peptidase S11 family
IGX36_RS17310	COG0583	DNA-binding transcription factor activity
IGX36_RS17320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IGX36_RS17325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IGX36_RS17345	COG3069	C4-dicarboxylate transmembrane transporter activity
IGX36_RS17350	COG4565	transcriptional regulatory protein
IGX36_RS17355	COG3290	protein histidine kinase activity
IGX36_RS17360	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IGX36_RS17370	COG2301	Belongs to the HpcH HpaI aldolase family
IGX36_RS17375	COG3051	citrate lyase alpha subunit
IGX36_RS17390	COG0471	metal ion transport
IGX36_RS17395	COG3719	Belongs to the RNase T2 family
IGX36_RS17400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IGX36_RS17405	COG0589	response to stress
IGX36_RS17415	COG3634	alkyl hydroperoxide reductase activity
IGX36_RS17420	COG0450	alkyl hydroperoxide reductase
IGX36_RS17425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IGX36_RS17430	COG0583	DNA-binding transcription factor activity
IGX36_RS17435	COG3969	phosphoadenosine phosphosulfate
IGX36_RS17440	COG1475	DNA binding
IGX36_RS17445	COG0436	Aminotransferase
IGX36_RS17450	COG0371	Dehydrogenase
IGX36_RS17455	COG2879	small protein
IGX36_RS17460	COG1966	Carbon starvation protein
IGX36_RS17465	COG2050	protein possibly involved in aromatic compounds catabolism
IGX36_RS17470	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS17475	COG3433	isochorismatase activity
IGX36_RS17475	COG1535	isochorismatase
IGX36_RS17480	COG1021	2,3-dihydroxybenzoate-AMP ligase
IGX36_RS17485	COG1169	isochorismate synthase
IGX36_RS17490	COG4592	Periplasmic binding protein
IGX36_RS17500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGX36_RS17505	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGX36_RS17510	COG1120	ATPase activity
IGX36_RS17515	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IGX36_RS17520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IGX36_RS17520	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IGX36_RS17525	COG3251	PFAM MbtH domain protein
IGX36_RS17530	COG2382	esterase
IGX36_RS17535	COG4771	TonB-dependent receptor
IGX36_RS17540	COG2977	Belongs to the P-Pant transferase superfamily
IGX36_RS17560	COG2315	Protein conserved in bacteria
IGX36_RS17565	COG0778	Nitroreductase
IGX36_RS17570	COG0668	transmembrane transport
IGX36_RS17575	COG1113	amino acid transport
IGX36_RS17580	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IGX36_RS17585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGX36_RS17590	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGX36_RS17595	COG1538	Outer membrane efflux protein
IGX36_RS17600	COG0745	RESPONSE REGULATOR receiver
IGX36_RS17605	COG5002	protein histidine kinase activity
IGX36_RS17630	COG5433	transposase activity
IGX36_RS17635	COG1215	transferase activity, transferring glycosyl groups
IGX36_RS17640	COG4783	chaperone-mediated protein folding
IGX36_RS17650	COG2207	Transcriptional regulator
IGX36_RS17655	COG4571	Outer membrane protease
IGX36_RS17670	COG0500	methyltransferase
IGX36_RS17695	COG4197	protein conserved in bacteria, prophage-related
IGX36_RS17700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IGX36_RS17720	COG5532	Uncharacterized conserved protein (DUF2303)
IGX36_RS17740	COG2197	response regulator
IGX36_RS17745	COG3539	Fimbrial protein
IGX36_RS17750	COG3539	Fimbrial protein
IGX36_RS17755	COG3188	usher protein
IGX36_RS17760	COG3121	Chaperone
IGX36_RS17765	COG3539	Fimbrial protein
IGX36_RS17775	COG2501	S4 domain
IGX36_RS17780	COG1988	membrane-bound metal-dependent
IGX36_RS17790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IGX36_RS17800	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IGX36_RS17805	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IGX36_RS17810	COG0549	Belongs to the carbamate kinase family
IGX36_RS17820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IGX36_RS17825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IGX36_RS17830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IGX36_RS17835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IGX36_RS17840	COG3257	ureidoglycine aminohydrolase activity
IGX36_RS17845	COG1929	Belongs to the glycerate kinase type-1 family
IGX36_RS17850	COG2233	PERMEase
IGX36_RS17860	COG1953	Uracil, thiamine, allantoin
IGX36_RS17865	COG2084	Dehydrogenase
IGX36_RS17870	COG3622	Belongs to the hyi family
IGX36_RS17875	COG3960	tartronate-semialdehyde synthase activity
IGX36_RS17880	COG1414	Transcriptional regulator
IGX36_RS17890	COG0583	DNA-binding transcription factor activity
IGX36_RS17915	COG3209	COG3209 Rhs family protein
IGX36_RS17925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IGX36_RS17930	COG4181	ATPase activity
IGX36_RS17935	COG2755	lipolytic protein G-D-S-L family
IGX36_RS17940	COG0300	oxidoreductase activity
IGX36_RS17945	COG3118	belongs to the thioredoxin family
IGX36_RS17950	COG0390	transport system, permease component
IGX36_RS17955	COG4619	ABC transporter
IGX36_RS17960	COG0330	HflC and HflK could
IGX36_RS17965	COG1585	Membrane protein implicated in regulation of membrane protease activity
IGX36_RS17985	COG0789	Transcriptional regulator
IGX36_RS18015	COG0531	amino acid
IGX36_RS18025	COG2217	Heavy metal translocating P-type atpase
IGX36_RS18030	COG3735	TraB family
IGX36_RS18035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IGX36_RS18040	COG0737	Belongs to the 5'-nucleotidase family
IGX36_RS18045	COG2223	nitrite transmembrane transporter activity
IGX36_RS18050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IGX36_RS18050	COG4651	solute:proton antiporter activity
IGX36_RS18055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGX36_RS18090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGX36_RS18100	COG2832	Protein of unknown function (DUF454)
IGX36_RS18105	COG3923	Primosomal replication protein n
IGX36_RS18120	COG1196	nuclear chromosome segregation
IGX36_RS18120	COG3264	Mechanosensitive ion channel
IGX36_RS18125	COG1309	transcriptional regulator
IGX36_RS18130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGX36_RS18135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IGX36_RS18150	COG0110	maltose O-acetyltransferase activity
IGX36_RS18160	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IGX36_RS18165	COG5507	3-demethylubiquinone-9 3-methyltransferase
IGX36_RS18175	COG3695	enzyme binding
IGX36_RS18180	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IGX36_RS18185	COG1946	Acyl-CoA thioesterase
IGX36_RS18190	COG0004	ammonium transporteR
IGX36_RS18195	COG0347	Belongs to the P(II) protein family
IGX36_RS18200	COG1132	(ABC) transporter
IGX36_RS18205	COG1132	(ABC) transporter
IGX36_RS18210	COG1522	sequence-specific DNA binding
IGX36_RS18215	COG0561	phosphatase activity
IGX36_RS18220	COG4533	DNA binding
IGX36_RS18230	COG0824	Thioesterase
IGX36_RS18235	COG1555	photosystem II stabilization
IGX36_RS18240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IGX36_RS18245	COG0776	regulation of translation
IGX36_RS18250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IGX36_RS18270	COG0271	Belongs to the BolA IbaG family
IGX36_RS18275	COG3056	Lipoprotein
IGX36_RS18280	COG2223	nitrite transmembrane transporter activity
IGX36_RS18285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IGX36_RS18290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IGX36_RS18295	COG1845	cytochrome c oxidase, subunit III
IGX36_RS18300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IGX36_RS18310	COG2814	Major facilitator Superfamily
IGX36_RS18320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IGX36_RS18325	COG0693	protein deglycase activity
IGX36_RS18340	COG0142	geranyltranstransferase activity
IGX36_RS18350	COG0667	Aldo Keto reductase
IGX36_RS18360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IGX36_RS18365	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IGX36_RS18380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IGX36_RS18380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IGX36_RS18390	COG4238	major outer membrane lipoprotein
IGX36_RS18395	COG3248	Nucleoside-binding outer membrane protein
IGX36_RS18400	COG1403	HNH endonuclease
IGX36_RS18405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IGX36_RS18410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IGX36_RS18415	COG1862	Preprotein translocase
IGX36_RS18440	COG0366	Alpha amylase catalytic
IGX36_RS18445	COG1113	amino acid transport
IGX36_RS18455	COG1114	Component of the transport system for branched-chain amino acids
IGX36_RS18460	COG5002	protein histidine kinase activity
IGX36_RS18465	COG0745	RESPONSE REGULATOR receiver
IGX36_RS18470	COG0420	3'-5' exonuclease activity
IGX36_RS18475	COG0419	ATPase involved in DNA repair
IGX36_RS18480	COG2814	Major facilitator Superfamily
IGX36_RS18485	COG1940	carbohydrate kinase activity
IGX36_RS18510	COG4126	flavin adenine dinucleotide binding
IGX36_RS18530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IGX36_RS18535	COG3706	GGDEF domain
IGX36_RS18545	COG1785	Belongs to the alkaline phosphatase family
IGX36_RS18560	COG1181	Belongs to the D-alanine--D-alanine ligase family
IGX36_RS18580	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IGX36_RS18585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IGX36_RS18590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IGX36_RS18595	COG3468	outer membrane autotransporter barrel domain protein
IGX36_RS18600	COG0113	porphobilinogen synthase activity
IGX36_RS18610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IGX36_RS18615	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IGX36_RS18620	COG4521	taurine ABC transporter
IGX36_RS18625	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IGX36_RS18630	COG1215	transferase activity, transferring glycosyl groups
IGX36_RS18660	COG3122	Protein conserved in bacteria
IGX36_RS18700	COG1414	Transcriptional regulator
IGX36_RS18705	COG1609	Transcriptional regulator
IGX36_RS18715	COG2223	nitrite transmembrane transporter activity
IGX36_RS18720	COG0110	maltose O-acetyltransferase activity
IGX36_RS18725	COG2807	transmembrane transport
IGX36_RS18735	COG0288	reversible hydration of carbon dioxide
IGX36_RS18740	COG0583	DNA-binding transcription factor activity
IGX36_RS18745	COG0402	S-adenosylhomocysteine deaminase activity
IGX36_RS18750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IGX36_RS18755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IGX36_RS18760	COG2079	MmgE PrpD family protein
IGX36_RS18765	COG0372	Belongs to the citrate synthase family
IGX36_RS18770	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IGX36_RS18775	COG3829	transcription factor binding
IGX36_RS18785	COG1280	lysine exporter protein (LysE YggA)
IGX36_RS18800	COG1064	alcohol dehydrogenase
IGX36_RS18815	COG1129	ABC transporter
IGX36_RS18820	COG1879	ABC-type sugar transport system periplasmic component
IGX36_RS18830	COG0402	S-adenosylhomocysteine deaminase activity
IGX36_RS18835	COG0549	Belongs to the carbamate kinase family
IGX36_RS18840	COG1304	FMN binding
IGX36_RS18845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IGX36_RS18865	COG0666	response to abiotic stimulus
IGX36_RS18875	COG0583	DNA-binding transcription factor activity
IGX36_RS18880	COG2771	luxR family
IGX36_RS18880	COG2200	EAL domain
IGX36_RS18885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IGX36_RS18910	COG1556	Lactate utilization protein
IGX36_RS18915	COG1139	Iron-sulfur cluster binding protein
IGX36_RS18920	COG0247	lactate metabolic process
IGX36_RS18925	COG2207	Transcriptional regulator
IGX36_RS18930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IGX36_RS18940	COG3059	membrane
IGX36_RS18945	COG0656	L-ascorbic acid biosynthetic process
IGX36_RS18950	COG2207	Transcriptional regulator
IGX36_RS18950	COG3708	Transcriptional regulator
IGX36_RS18960	COG0656	L-ascorbic acid biosynthetic process
IGX36_RS18965	COG0667	Aldo Keto reductase
IGX36_RS18975	COG0583	DNA-binding transcription factor activity
IGX36_RS18985	COG1073	alpha beta
IGX36_RS18990	COG1902	pentaerythritol trinitrate reductase activity
IGX36_RS19045	COG0727	PFAM Uncharacterised protein family (UPF0153)
IGX36_RS19050	COG3477	response to acidic pH
IGX36_RS19055	COG2080	2 iron, 2 sulfur cluster binding
IGX36_RS19060	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IGX36_RS19065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IGX36_RS19070	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IGX36_RS19085	COG0583	DNA-binding transcription factor activity
IGX36_RS19145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IGX36_RS19165	COG2195	Cleaves the N-terminal amino acid of tripeptides
IGX36_RS19180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IGX36_RS19185	COG1690	Belongs to the RtcB family
IGX36_RS19190	COG0454	-acetyltransferase
IGX36_RS19200	COG2161	toxin-antitoxin pair type II binding
IGX36_RS19230	COG0791	NLP P60 protein
IGX36_RS19235	COG3034	peptidoglycan biosynthetic process
IGX36_RS19240	COG0121	glutamine amidotransferase
IGX36_RS19250	COG1960	acyl-CoA dehydrogenase activity
IGX36_RS19260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IGX36_RS19345	COG3157	Type VI secretion system effector, Hcp
IGX36_RS19350	COG4104	PAAR repeat-containing protein
IGX36_RS19375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IGX36_RS19385	COG2226	methyltransferase
IGX36_RS19395	COG0741	lytic transglycosylase activity
IGX36_RS19395	COG1388	LysM domain
IGX36_RS19400	COG2226	methyltransferase
IGX36_RS19410	COG0583	DNA-binding transcription factor activity
IGX36_RS19415	COG0656	L-ascorbic acid biosynthetic process
IGX36_RS19450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IGX36_RS19455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IGX36_RS19460	COG2011	ABC-type metal ion transport system permease component
IGX36_RS19465	COG1464	Belongs to the NlpA lipoprotein family
IGX36_RS19475	COG1720	tRNA m6t6A37 methyltransferase activity
IGX36_RS19485	COG0791	NLP P60 protein
IGX36_RS19490	COG3015	lipoprotein NlpE involved in copper resistance
IGX36_RS19495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IGX36_RS19500	COG4681	YaeQ
IGX36_RS19510	COG4568	rho-dependent transcription termination
IGX36_RS19515	COG0037	tRNA processing
IGX36_RS19520	COG0346	lactoylglutathione lyase activity
IGX36_RS19525	COG1982	Orn Lys Arg decarboxylase major
IGX36_RS19535	COG0587	DNA-directed DNA polymerase activity
IGX36_RS19540	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGX36_RS19560	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IGX36_RS19565	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IGX36_RS19580	COG0575	Belongs to the CDS family
IGX36_RS19585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IGX36_RS19590	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IGX36_RS19615	COG0024	Methionine aminopeptidase
IGX36_RS19635	COG3835	regulator
IGX36_RS19640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IGX36_RS19655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IGX36_RS19660	COG2860	membrane
IGX36_RS19685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGX36_RS19690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IGX36_RS19695	COG1120	ATPase activity
IGX36_RS19705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IGX36_RS19710	COG1643	Atp-dependent helicase
IGX36_RS19715	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IGX36_RS19725	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IGX36_RS19730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IGX36_RS19735	COG0617	tRNA 3'-terminal CCA addition
IGX36_RS19740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IGX36_RS19745	COG3539	Fimbrial protein
IGX36_RS19750	COG3121	Chaperone
IGX36_RS19755	COG3188	usher protein
IGX36_RS19760	COG3539	Fimbrial protein
IGX36_RS19770	COG3539	Fimbrial protein
IGX36_RS19790	COG5464	transposase or invertase
IGX36_RS19800	COG0726	polysaccharide deacetylase
IGX36_RS19805	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS19810	COG0842	Transport permease protein
IGX36_RS19815	COG1131	(ABC) transporter
IGX36_RS19820	COG0288	reversible hydration of carbon dioxide
IGX36_RS19825	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IGX36_RS19830	COG4993	Dehydrogenase
IGX36_RS19835	COG2132	Multicopper oxidase
IGX36_RS19860	COG1049	propionate catabolic process, 2-methylcitrate cycle
IGX36_RS19865	COG3064	Membrane
IGX36_RS19870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IGX36_RS19875	COG0508	dehydrogenase complex catalyzes the overall conversion of
IGX36_RS19880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IGX36_RS19885	COG2186	Transcriptional regulator
IGX36_RS19895	COG3725	Membrane protein required for beta-lactamase induction
IGX36_RS19900	COG3023	N-Acetylmuramoyl-L-alanine amidase
IGX36_RS19905	COG0157	Belongs to the NadC ModD family
IGX36_RS19910	COG4969	Belongs to the N-Me-Phe pilin family
IGX36_RS19915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IGX36_RS19935	COG0237	dephospho-CoA kinase activity
IGX36_RS19950	COG0494	nUDIX hydrolase
IGX36_RS19970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IGX36_RS19975	COG0849	cell division
IGX36_RS19980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IGX36_RS19985	COG1181	Belongs to the D-alanine--D-alanine ligase family
IGX36_RS20000	COG0772	Belongs to the SEDS family
IGX36_RS20015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IGX36_RS20020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IGX36_RS20025	COG0768	penicillin binding
IGX36_RS20030	COG3116	cell division
IGX36_RS20045	COG1609	Transcriptional regulator
IGX36_RS20055	COG0440	acetolactate synthase activity
IGX36_RS20060	COG0028	Belongs to the TPP enzyme family
IGX36_RS20070	COG0583	DNA-binding transcription factor activity
IGX36_RS20105	COG4533	DNA binding
IGX36_RS20115	COG4143	(ABC) transporter
IGX36_RS20120	COG1178	ABC-type Fe3 transport system permease component
IGX36_RS20130	COG0586	Pfam SNARE associated Golgi protein
IGX36_RS20135	COG4977	sequence-specific DNA binding
IGX36_RS20150	COG0235	Class ii aldolase
IGX36_RS20155	COG0417	DNA replication proofreading
IGX36_RS20165	COG0564	pseudouridine synthase activity
IGX36_RS20175	COG1357	PFAM Pentapeptide repeats (8 copies)
IGX36_RS20180	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IGX36_RS20185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IGX36_RS20190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IGX36_RS20230	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IGX36_RS20245	COG2271	Major facilitator Superfamily
IGX36_RS20250	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IGX36_RS20255	COG0644	oxidoreductase
IGX36_RS20305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IGX36_RS20310	COG0505	Belongs to the CarA family
IGX36_RS20330	COG1047	Peptidyl-prolyl cis-trans
IGX36_RS20345	COG0196	riboflavin kinase activity
IGX36_RS20375	COG3188	usher protein
IGX36_RS20385	COG0583	DNA-binding transcription factor activity
IGX36_RS20415	COG4735	regulation of single-species biofilm formation
IGX36_RS20420	COG1584	GPR1 FUN34 yaaH family protein
IGX36_RS20425	COG0521	Mo-molybdopterin cofactor biosynthetic process
IGX36_RS20435	COG1115	amino acid carrier protein
IGX36_RS20450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IGX36_RS20460	COG0460	homoserine dehydrogenase
IGX36_RS20460	COG0527	aspartate kinase activity
IGX36_RS20470	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IGX36_RS20480	COG0745	RESPONSE REGULATOR receiver
IGX36_RS20485	COG4452	Inner membrane protein CreD
IGX36_RS20490	COG2205	protein histidine kinase activity
IGX36_RS20495	COG0745	RESPONSE REGULATOR receiver
IGX36_RS20500	COG3045	CreA protein
IGX36_RS20505	COG2207	Transcriptional regulator
IGX36_RS20505	COG3708	Transcriptional regulator
IGX36_RS20525	COG0741	lytic transglycosylase activity
IGX36_RS20530	COG0488	(ABC) transporter
IGX36_RS20535	COG0583	DNA-binding transcription factor activity
IGX36_RS20545	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS20560	COG1902	pentaerythritol trinitrate reductase activity
IGX36_RS20565	COG1056	cytidyltransferase-related domain
IGX36_RS20565	COG3172	ATPase kinase involved in NAD metabolism
IGX36_RS20570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IGX36_RS20575	COG0560	Phosphoserine phosphatase
IGX36_RS20580	COG3726	membrane protein affecting hemolysin expression
IGX36_RS20615	COG1328	CTP reductase activity
IGX36_RS20620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IGX36_RS20625	COG0084	hydrolase, TatD family'
IGX36_RS20630	COG4667	esterase of the alpha-beta hydrolase superfamily
IGX36_RS20640	COG2823	Periplasmic or secreted lipoprotein
IGX36_RS20755	COG1403	HNH endonuclease
IGX36_RS20790	COG5532	Uncharacterized conserved protein (DUF2303)
IGX36_RS20795	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IGX36_RS20810	COG1011	Hydrolase
IGX36_RS20815	COG0456	acetyltransferase
IGX36_RS20820	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IGX36_RS20850	COG4114	ferric iron reductase
IGX36_RS20855	COG2197	response regulator
IGX36_RS20860	COG2197	response regulator
IGX36_RS20865	COG2966	Psort location CytoplasmicMembrane, score
IGX36_RS20880	COG1484	DNA-dependent DNA replication
IGX36_RS20895	COG1063	alcohol dehydrogenase
IGX36_RS20900	COG1802	Transcriptional regulator
IGX36_RS20905	COG2271	Major facilitator Superfamily
IGX36_RS20910	COG0840	transmembrane signaling receptor activity
IGX36_RS20915	COG1966	Carbon starvation protein
IGX36_RS20920	COG2879	small protein
IGX36_RS20925	COG0523	cobalamin synthesis protein
IGX36_RS20950	COG2814	Major facilitator Superfamily
IGX36_RS20955	COG2733	membrane
IGX36_RS20960	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
IGX36_RS20965	COG1924	4 iron, 4 sulfur cluster binding
IGX36_RS20980	COG0477	Major facilitator Superfamily
IGX36_RS20990	COG3366	ferrous iron transmembrane transporter activity
IGX36_RS20995	COG0700	Nucleoside recognition
IGX36_RS21000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IGX36_RS21005	COG0583	DNA-binding transcription factor activity
IGX36_RS21025	COG2186	Transcriptional regulator
IGX36_RS21030	COG0246	Mannitol dehydrogenase
IGX36_RS21040	COG2610	gluconate transmembrane transporter activity
IGX36_RS21045	COG3539	Fimbrial protein
IGX36_RS21050	COG3539	Fimbrial protein
IGX36_RS21055	COG3539	Fimbrial protein
IGX36_RS21060	COG3188	usher protein
IGX36_RS21070	COG3539	Fimbrial protein
IGX36_RS21080	COG4974	Belongs to the 'phage' integrase family
IGX36_RS21085	COG0582	viral genome integration into host DNA
IGX36_RS21100	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IGX36_RS21120	COG2003	Belongs to the UPF0758 family
IGX36_RS21155	COG1595	DNA-templated transcription, initiation
IGX36_RS21160	COG3712	iron ion homeostasis
IGX36_RS21165	COG4772	TonB-dependent receptor
IGX36_RS21170	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IGX36_RS21175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGX36_RS21180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGX36_RS21185	COG1120	ATPase activity
IGX36_RS21190	COG2085	NADP oxidoreductase coenzyme F420-dependent
IGX36_RS21260	COG1064	alcohol dehydrogenase
IGX36_RS21265	COG0433	COG0433 Predicted ATPase
IGX36_RS21270	COG0795	lipopolysaccharide-transporting ATPase activity
IGX36_RS21275	COG0795	lipopolysaccharide-transporting ATPase activity
IGX36_RS21285	COG2927	DNA polymerase III (CHI subunit)
IGX36_RS21300	COG0456	acetyltransferase
IGX36_RS21305	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IGX36_RS21320	COG2731	YhcH YjgK YiaL family protein
IGX36_RS21325	COG1309	transcriptional regulator
IGX36_RS21330	COG1028	Short-chain dehydrogenase reductase Sdr
IGX36_RS21335	COG0251	oxidation-reduction process
IGX36_RS21355	COG0251	oxidation-reduction process
IGX36_RS21360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IGX36_RS21370	COG1609	Transcriptional regulator
IGX36_RS21375	COG1263	PTS System
IGX36_RS21375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IGX36_RS21380	COG0366	Alpha amylase catalytic
IGX36_RS21385	COG1328	CTP reductase activity
IGX36_RS21390	COG0602	queuosine metabolic process
IGX36_RS21395	COG3783	Cytochrome b(562)
IGX36_RS21400	COG0312	modulator of DNA gyrase
IGX36_RS21410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IGX36_RS21420	COG1172	Belongs to the binding-protein-dependent transport system permease family
IGX36_RS21425	COG1172	Belongs to the binding-protein-dependent transport system permease family
IGX36_RS21430	COG1129	ABC transporter
IGX36_RS21435	COG1879	ABC-type sugar transport system periplasmic component
IGX36_RS21440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IGX36_RS21445	COG2105	PFAM AIG2 family protein
IGX36_RS21450	COG2911	Protein conserved in bacteria
IGX36_RS21455	COG0729	surface antigen
IGX36_RS21465	COG1253	flavin adenine dinucleotide binding
IGX36_RS21475	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IGX36_RS21480	COG1218	3'(2'),5'-bisphosphate nucleotidase
IGX36_RS21485	COG0737	Belongs to the 5'-nucleotidase family
IGX36_RS21490	COG1733	regulation of RNA biosynthetic process
IGX36_RS21495	COG0702	epimerase
IGX36_RS21500	COG0697	spore germination
IGX36_RS21510	COG1113	amino acid transport
IGX36_RS21515	COG0545	Peptidyl-prolyl cis-trans isomerase
IGX36_RS21520	COG3061	Opacity-associated protein A
IGX36_RS21540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IGX36_RS21580	COG3414	Phosphotransferase system galactitol-specific IIB component
IGX36_RS21585	COG3037	sugar-specific permease SgaT UlaA
IGX36_RS21600	COG1073	alpha beta
IGX36_RS21605	COG3650	response to hydrogen peroxide
IGX36_RS21615	COG1960	acyl-CoA dehydrogenase activity
IGX36_RS21620	COG0754	glutathionylspermidine amidase activity
IGX36_RS21625	COG5463	Belongs to the UPF0441 family
IGX36_RS21630	COG3766	membrane
IGX36_RS21640	COG1842	Phage shock protein A
IGX36_RS21645	COG3789	protein conserved in bacteria
IGX36_RS21650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGX36_RS21655	COG0557	exoribonuclease II activity
IGX36_RS21670	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IGX36_RS21675	COG0330	HflC and HflK could
IGX36_RS21680	COG0330	HflC and HflK could
IGX36_RS21685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IGX36_RS21705	COG0860	N-Acetylmuramoyl-L-alanine amidase
IGX36_RS21710	COG0802	atpase or kinase
IGX36_RS21715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IGX36_RS21715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IGX36_RS21760	COG1511	domain protein
IGX36_RS21760	COG3264	Mechanosensitive ion channel
IGX36_RS21765	COG0531	amino acid
IGX36_RS21775	COG1053	succinate dehydrogenase
IGX36_RS21780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IGX36_RS21795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IGX36_RS21800	COG3040	lipid binding
IGX36_RS21805	COG2076	Multidrug Resistance protein
IGX36_RS21810	COG5510	response to toxic substance
IGX36_RS21815	COG5510	response to toxic substance
IGX36_RS21825	COG1509	lysine 2,3-aminomutase activity
IGX36_RS21850	COG0531	amino acid
IGX36_RS21855	COG3030	protein affecting phage T7 exclusion by the F plasmid
IGX36_RS21860	COG1027	Aspartate ammonia-lyase
IGX36_RS21865	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IGX36_RS21875	COG4232	protein-disulfide reductase activity
IGX36_RS21880	COG1309	transcriptional regulator
IGX36_RS21890	COG0582	viral genome integration into host DNA
IGX36_RS22005	COG4983	Phage plasmid primase, P4 family domain protein
IGX36_RS22015	COG3468	outer membrane autotransporter barrel domain protein
IGX36_RS22035	COG3710	Transcriptional regulator
IGX36_RS22040	COG0531	amino acid
IGX36_RS22045	COG1982	Orn Lys Arg decarboxylase major
IGX36_RS22050	COG3104	oligopeptide transport
IGX36_RS22055	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IGX36_RS22070	COG2388	GCN5-related N-acetyl-transferase
IGX36_RS22075	COG3592	Divergent 4Fe-4S mono-cluster
IGX36_RS22080	COG3290	protein histidine kinase activity
IGX36_RS22085	COG4565	transcriptional regulatory protein
IGX36_RS22090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IGX36_RS22095	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IGX36_RS22095	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IGX36_RS22100	COG3647	Membrane
IGX36_RS22105	COG1486	melibiose metabolic process
IGX36_RS22110	COG2169	Transcriptional regulator
IGX36_RS22115	COG1982	Orn Lys Arg decarboxylase major
IGX36_RS22120	COG2207	Transcriptional regulator
IGX36_RS22125	COG0531	amino acid
IGX36_RS22130	COG2194	sulfuric ester hydrolase activity
IGX36_RS22135	COG0745	RESPONSE REGULATOR receiver
IGX36_RS22140	COG0642	Histidine kinase
IGX36_RS22150	COG0477	Major facilitator Superfamily
IGX36_RS22160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IGX36_RS22170	COG2824	Alkylphosphonate utilization operon protein PhnA
IGX36_RS22175	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IGX36_RS22185	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IGX36_RS22190	COG3639	organic phosphonate transmembrane transporter activity
IGX36_RS22195	COG2188	Transcriptional regulator
IGX36_RS22200	COG3624	Phosphonate C-P lyase system protein PhnG
IGX36_RS22205	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IGX36_RS22210	COG3626	phosphonate metabolism
IGX36_RS22215	COG3627	carbon phosphorus lyase activity
IGX36_RS22220	COG4107	phosphonate C-P lyase system protein PhnK
IGX36_RS22225	COG4778	phosphonate C-P lyase system protein PhnL
IGX36_RS22230	COG3454	Phosphonate metabolism
IGX36_RS22240	COG0456	acetyltransferase
IGX36_RS22245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IGX36_RS22255	COG0698	ribose 5-phosphate isomerase
IGX36_RS22260	COG1737	Transcriptional regulator
IGX36_RS22265	COG1879	ABC-type sugar transport system periplasmic component
IGX36_RS22270	COG1129	ABC transporter
IGX36_RS22275	COG1172	Belongs to the binding-protein-dependent transport system permease family
IGX36_RS22280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IGX36_RS22285	COG1940	carbohydrate kinase activity
IGX36_RS22290	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IGX36_RS22300	COG1566	PFAM secretion protein HlyD family protein
IGX36_RS22305	COG1289	transmembrane transporter activity
IGX36_RS22320	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IGX36_RS22325	COG1301	dicarboxylic acid transport
IGX36_RS22330	COG4235	cytochrome complex assembly
IGX36_RS22335	COG3088	subunit of a heme lyase
IGX36_RS22340	COG1138	Cytochrome C-type biogenesis protein
IGX36_RS22345	COG3301	Polysulphide reductase, NrfD
IGX36_RS22350	COG0437	4 iron, 4 sulfur cluster binding
IGX36_RS22355	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IGX36_RS22365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IGX36_RS22370	COG3162	membrane
IGX36_RS22380	COG1357	PFAM Pentapeptide repeats (8 copies)
IGX36_RS22385	COG0025	NhaP-type Na H and K H
IGX36_RS22390	COG2252	PERMEase
IGX36_RS22395	COG0789	Transcriptional regulator
IGX36_RS22400	COG2207	Transcriptional regulator
IGX36_RS22405	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IGX36_RS22415	COG0629	single-stranded DNA binding
IGX36_RS22420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IGX36_RS22425	COG2315	Protein conserved in bacteria
IGX36_RS22430	COG0432	Pfam Uncharacterised protein family UPF0047
IGX36_RS22435	COG3700	Belongs to the class B bacterial acid phosphatase family
IGX36_RS22445	COG1448	Aminotransferase
IGX36_RS22450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IGX36_RS22455	COG0305	Participates in initiation and elongation during chromosome replication
IGX36_RS22460	COG0604	alcohol dehydrogenase
IGX36_RS22470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGX36_RS22480	COG0735	belongs to the Fur family
IGX36_RS22485	COG3237	CsbD-like
IGX36_RS22490	COG0534	Mate efflux family protein
IGX36_RS22500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IGX36_RS22520	COG1357	PFAM Pentapeptide repeats (8 copies)
IGX36_RS22535	COG3842	ATPase activity
IGX36_RS22540	COG2182	Extracellular solute-binding protein
IGX36_RS22545	COG1175	transmembrane transport
IGX36_RS22550	COG3833	ABC-type maltose transport systems, permease component
IGX36_RS22555	COG2814	Major facilitator Superfamily
IGX36_RS22555	COG0477	Major facilitator Superfamily
IGX36_RS22570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IGX36_RS22595	COG0527	aspartate kinase activity
IGX36_RS22605	COG1187	pseudouridine synthase activity
IGX36_RS22660	COG1283	sodium-dependent phosphate transmembrane transporter activity
IGX36_RS22665	COG1410	methionine synthase
IGX36_RS22665	COG0646	methionine synthase
IGX36_RS22670	COG1414	Transcriptional regulator
IGX36_RS22685	COG2224	Isocitrate lyase
IGX36_RS22690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IGX36_RS22700	COG0456	acetyltransferase
IGX36_RS22730	COG0151	Belongs to the GarS family
IGX36_RS22735	COG2204	response regulator
IGX36_RS22740	COG4191	Histidine kinase
IGX36_RS22745	COG3678	ATP-independent chaperone mediated protein folding
IGX36_RS22760	COG3068	Protein conserved in bacteria
IGX36_RS22795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IGX36_RS22800	COG2104	thiamine diphosphate biosynthetic process
IGX36_RS22810	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IGX36_RS22845	COG0250	Participates in transcription elongation, termination and antitermination
IGX36_RS22850	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IGX36_RS22885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IGX36_RS22885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IGX36_RS22890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IGX36_RS22935	COG1309	transcriptional regulator
IGX36_RS22945	COG0583	DNA-binding transcription factor activity
IGX36_RS22960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IGX36_RS22975	COG2194	sulfuric ester hydrolase activity
IGX36_RS22980	COG2207	Transcriptional regulator
IGX36_RS22985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS22990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IGX36_RS22995	COG1882	Formate acetyltransferase
IGX36_RS23000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS23005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS23010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS23010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGX36_RS23010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS23015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IGX36_RS23020	COG0371	Dehydrogenase
IGX36_RS23025	COG3738	Protein conserved in bacteria
IGX36_RS23030	COG0697	spore germination
IGX36_RS23040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IGX36_RS23045	COG0737	Belongs to the 5'-nucleotidase family
IGX36_RS23055	COG0527	aspartate kinase activity
IGX36_RS23055	COG0460	homoserine dehydrogenase
IGX36_RS23060	COG0626	cystathionine gamma-synthase activity
IGX36_RS23070	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IGX36_RS23080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IGX36_RS23085	COG1609	Transcriptional regulator
IGX36_RS23090	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IGX36_RS23105	COG1575	Belongs to the MenA family. Type 1 subfamily
IGX36_RS23120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IGX36_RS23130	COG1494	fructose-1,6-bisphosphatase
IGX36_RS23140	COG0589	response to stress
IGX36_RS23145	COG3691	Protein conserved in bacteria
IGX36_RS23150	COG3152	Membrane
IGX36_RS23170	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IGX36_RS23205	COG4695	Portal protein
IGX36_RS23265	COG4974	Belongs to the 'phage' integrase family
IGX36_RS23270	COG3678	ATP-independent chaperone mediated protein folding
IGX36_RS23275	COG0745	RESPONSE REGULATOR receiver
IGX36_RS23280	COG2205	protein histidine kinase activity
IGX36_RS23285	COG2258	MOSC domain
IGX36_RS23295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IGX36_RS23305	COG1917	Cupin 2, conserved barrel domain protein
IGX36_RS23305	COG4977	sequence-specific DNA binding
IGX36_RS23340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS23345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS23345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IGX36_RS23350	COG1363	Peptidase, m42
IGX36_RS23355	COG3711	transcriptional antiterminator
IGX36_RS23355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IGX36_RS23375	COG0437	4 iron, 4 sulfur cluster binding
IGX36_RS23380	COG2864	formate dehydrogenase
IGX36_RS23390	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IGX36_RS23415	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
IGX36_RS23420	COG0657	acetylesterase activity
IGX36_RS23430	COG0456	acetyltransferase
IGX36_RS23445	COG1011	Hydrolase
IGX36_RS23450	COG1349	DNA-binding transcription factor activity
IGX36_RS23455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGX36_RS23460	COG2084	Dehydrogenase
IGX36_RS23465	COG3684	Belongs to the aldolase LacD family
IGX36_RS23470	COG2942	2-epimerase
IGX36_RS23475	COG2017	converts alpha-aldose to the beta-anomer
IGX36_RS23480	COG1501	Belongs to the glycosyl hydrolase 31 family
IGX36_RS23485	COG2211	Major facilitator Superfamily
IGX36_RS23490	COG2211	Major facilitator Superfamily
IGX36_RS23495	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IGX36_RS23505	COG2271	Major facilitator Superfamily
IGX36_RS23510	COG1082	Xylose isomerase domain protein TIM barrel
IGX36_RS23515	COG2188	Transcriptional regulator
IGX36_RS23520	COG1217	gtp-binding protein TYPA
IGX36_RS23525	COG0174	glutamine synthetase
IGX36_RS23530	COG3852	Histidine kinase
IGX36_RS23535	COG2204	response regulator
IGX36_RS23545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IGX36_RS23560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IGX36_RS23560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IGX36_RS23565	COG0204	Acyl-transferase
IGX36_RS23570	COG5339	Protein conserved in bacteria
IGX36_RS23575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IGX36_RS23580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IGX36_RS23585	COG3084	Protein conserved in bacteria
IGX36_RS23590	COG0746	molybdenum cofactor guanylyltransferase activity
IGX36_RS23595	COG1763	Mo-molybdopterin cofactor biosynthetic process
IGX36_RS23625	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IGX36_RS23630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IGX36_RS23635	COG1739	Uncharacterized protein family UPF0029
IGX36_RS23650	COG0183	Belongs to the thiolase family
IGX36_RS23655	COG0543	2 iron, 2 sulfur cluster binding
IGX36_RS23660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IGX36_RS23665	COG0250	Participates in transcription elongation, termination and antitermination
IGX36_RS23675	COG0805	protein transport
IGX36_RS23685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IGX36_RS23695	COG3165	ubiquinone biosynthetic process from chorismate
IGX36_RS23705	COG1322	Protein conserved in bacteria
IGX36_RS23710	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IGX36_RS23715	COG0412	Dienelactone hydrolase
IGX36_RS23720	COG3157	Type VI secretion system effector, Hcp
IGX36_RS23735	COG0583	DNA-binding transcription factor activity
IGX36_RS23740	COG0697	spore germination
IGX36_RS23745	COG0561	phosphatase activity
IGX36_RS23750	COG2267	carboxylic ester hydrolase activity
IGX36_RS23755	COG1280	lysine exporter protein (LysE YggA)
IGX36_RS23760	COG1280	lysine exporter protein (LysE YggA)
IGX36_RS23765	COG0514	ATP-dependent DNA helicase (RecQ)
IGX36_RS23770	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IGX36_RS23775	COG2050	protein possibly involved in aromatic compounds catabolism
IGX36_RS23780	COG2962	Rard protein
IGX36_RS23795	COG0598	Magnesium transport protein CorA
IGX36_RS23800	COG3698	Phosphodiester glycosidase
IGX36_RS23805	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
IGX36_RS23810	COG0210	DNA helicase
IGX36_RS23815	COG1011	Hydrolase
IGX36_RS23825	COG3159	Protein conserved in bacteria
IGX36_RS23835	COG5567	small periplasmic lipoprotein
IGX36_RS23850	COG3072	Adenylate cyclase
IGX36_RS23860	COG1587	Uroporphyrinogen-III synthase
IGX36_RS23865	COG2959	enzyme of heme biosynthesis
IGX36_RS23870	COG3071	HemY protein
IGX36_RS23875	COG3119	arylsulfatase activity
IGX36_RS23880	COG0641	radical SAM
IGX36_RS23905	COG1113	amino acid transport
IGX36_RS23925	COG2244	polysaccharide biosynthetic process
IGX36_RS23930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IGX36_RS23935	COG0456	acetyltransferase
IGX36_RS23940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IGX36_RS23945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IGX36_RS23950	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IGX36_RS23955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IGX36_RS23960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IGX36_RS23970	COG3118	belongs to the thioredoxin family
IGX36_RS23985	COG0210	DNA helicase
IGX36_RS23990	COG3692	DNA binding
IGX36_RS23995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IGX36_RS24005	COG0583	DNA-binding transcription factor activity
IGX36_RS24010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IGX36_RS24020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IGX36_RS24025	COG3978	acetolactate synthase activity
IGX36_RS24045	COG0606	chelatase, subunit chli
IGX36_RS24050	COG3085	chromosome segregation
IGX36_RS24090	COG2186	Transcriptional regulator
IGX36_RS24095	COG0477	Major facilitator Superfamily
IGX36_RS24100	COG1609	Transcriptional regulator
IGX36_RS24105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGX36_RS24110	COG1879	ABC-type sugar transport system periplasmic component
IGX36_RS24115	COG1172	Belongs to the binding-protein-dependent transport system permease family
IGX36_RS24120	COG1129	ABC transporter
IGX36_RS24150	COG1522	sequence-specific DNA binding
IGX36_RS24155	COG0716	FMN binding
IGX36_RS24170	COG3312	ion transport
IGX36_RS24225	COG3539	Fimbrial protein
IGX36_RS24245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IGX36_RS24250	COG0573	inorganic phosphate transmembrane transporter activity
IGX36_RS24255	COG0581	inorganic phosphate transmembrane transporter activity
IGX36_RS24260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IGX36_RS24265	COG0704	Plays a role in the regulation of phosphate uptake
IGX36_RS24285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IGX36_RS24290	COG2252	PERMEase
IGX36_RS24295	COG0431	NADPH-dependent FMN reductase
IGX36_RS24300	COG2091	lysine biosynthetic process via aminoadipic acid
IGX36_RS24315	COG0814	amino acid