locus-tag class description GUU87_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) GUU87_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GUU87_RS00030 ENOG4105VP5 Bacterial protein of unknown function (DUF937) GUU87_RS00035 ENOG410667J hydrolase GUU87_RS00040 ENOG410657R replicase EC 2.7 GUU87_RS00045 ENOG4105EMF GntR family transcriptional regulator GUU87_RS00050 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 GUU87_RS00055 ENOG4108RTU Aldolase GUU87_RS00065 ENOG4105DJB Major Facilitator Superfamily GUU87_RS00075 ENOG4105D99 atp gtp-binding protein GUU87_RS00080 ENOG4105R2A (LipO)protein GUU87_RS00100 ENOG4105FDP GntR family transcriptional regulator GUU87_RS00105 ENOG4105CI1 PTS System GUU87_RS00120 ENOG4108AHD Transcriptional regulator GUU87_RS00125 ENOG4107RUZ Sss sodium solute transporter superfamily GUU87_RS00130 ENOG4105CBG Sulfatase GUU87_RS00135 ENOG4106DRA Inner membrane protein YidI GUU87_RS00140 ENOG4105VG5 Membrane GUU87_RS00145 ENOG4105JP4 Inner membrane protein yidG GUU87_RS00150 ENOG4105J13 transcriptional regulator GUU87_RS00155 ENOG4105E5M Multidrug resistance protein D GUU87_RS00170 ENOG4105C7K acetolactate synthase GUU87_RS00175 ENOG4105M71 acetolactate synthase 1 regulatory subunit GUU87_RS00180 ENOG4108KX4 response regulator GUU87_RS00185 ENOG4105BZU Histidine kinase GUU87_RS00190 ENOG4105CXY transporter GUU87_RS00195 ENOG4105CXY transporter GUU87_RS00205 ENOG4105C7N Xanthine uracil vitamin C permease GUU87_RS00210 ENOG4108SAJ Protein of unknown function (DUF1198) GUU87_RS00220 ENOG4105T8A Uncharacterized protein YicS GUU87_RS00225 ENOG4105D01 (LipO)protein GUU87_RS00230 ENOG4108UZ3 Transporter GUU87_RS00235 ENOG4105S8Q sugar efflux transporter GUU87_RS00250 ENOG4105CT4 transporter GUU87_RS00255 ENOG4105CJQ hydrolase, family 31 GUU87_RS00260 ENOG4105JV1 AsmA family GUU87_RS00265 ENOG4105C2W permease GUU87_RS00270 ENOG4105D6U Sodium Glutamate Symporter GUU87_RS00280 ENOG4105CB5 ATP-dependent DNA helicase recG GUU87_RS00285 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase GUU87_RS00290 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) GUU87_RS00295 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) GUU87_RS00300 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) GUU87_RS00310 ENOG4105EN6 Membrane GUU87_RS00315 ENOG4105F5P DNA-damage-inducible protein d GUU87_RS00320 ENOG4105DSJ YicC domain protein GUU87_RS00330 ENOG4107QP2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) GUU87_RS00345 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase GUU87_RS00360 ENOG4105W0E 50S ribosomal protein L33 GUU87_RS00375 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase GUU87_RS00380 ENOG4105DKP glycosyl transferase, family 9 GUU87_RS00385 ENOG4107RJ7 Glycosyl transferase (Group 1 GUU87_RS00390 ENOG4107543 (lipo)polysaccharide GUU87_RS00395 ENOG4106AH0 Glycosyl Transferase GUU87_RS00400 ENOG4105X1N Glycosyl transferase family 8 GUU87_RS00410 ENOG4105X1N Glycosyl transferase family 8 GUU87_RS00415 ENOG4105K64 Glycosyl transferase, family 2 GUU87_RS00420 ENOG41068PG O-Antigen polymerase GUU87_RS00425 ENOG4105D16 lipopolysaccharide heptosyltransferase i GUU87_RS00430 ENOG4105XA0 heptosyltransferase ii GUU87_RS00440 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) GUU87_RS00450 ENOG4105K64 Glycosyl transferase, family 2 GUU87_RS00455 ENOG4105PXI polysaccharide deacetylase GUU87_RS00460 ENOG41063SB peptidase GUU87_RS00470 ENOG4107YZP Rhodanese domain protein GUU87_RS00475 ENOG4105VW4 glutaredoxin 3 GUU87_RS00490 ENOG4105D7W serine acetyltransferase GUU87_RS00495 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) GUU87_RS00505 ENOG41073TP transcriptional regulator GUU87_RS00510 ENOG4105DAA L-lactate GUU87_RS00515 ENOG4105EUR Domain-Containing protein GUU87_RS00520 ENOG4108WY4 inner membrane lipoprotein GUU87_RS00525 ENOG4108YYI Protein of unknown function (DUF2810) GUU87_RS00535 ENOG4105E61 Mannitol repressor protein GUU87_RS00545 ENOG4105CTS PTS system mannitol-specific GUU87_RS00550 ENOG4105FP6 Protein of unknown function (DUF3302) GUU87_RS00555 ENOG4105EFX secretion protein, HlyD family GUU87_RS00575 ENOG4105NUP lyase containing HEAT-repeat GUU87_RS00585 ENOG4105CNA YD repeat protein GUU87_RS00590 ENOG4108U78 Glutathione S-transferase GUU87_RS00600 ENOG4105EM7 Selenocysteine-specific translation elongation factor GUU87_RS00605 ENOG4105C0A alcohol dehydrogenase GUU87_RS00610 ENOG4105C26 Dehydrogenase GUU87_RS00620 ENOG4105KK7 inner membrane protein YiaW GUU87_RS00625 ENOG4105EFX secretion protein, HlyD family GUU87_RS00630 ENOG4108Q2M Transcriptional regulator GUU87_RS00635 ENOG4105GNX MltA-interacting MipA family protein GUU87_RS00645 ENOG4105CT4 transporter GUU87_RS00655 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase GUU87_RS00660 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase GUU87_RS00665 ENOG4105H6Q decarboxylase GUU87_RS00670 ENOG4105CMG Carbohydrate kinase GUU87_RS00675 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit GUU87_RS00680 ENOG4105CG6 trap dicarboxylate transporter dctm subunit GUU87_RS00685 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter GUU87_RS00690 ENOG4108R66 Conserved Protein GUU87_RS00700 ENOG4105J4Q Transcriptional regulator GUU87_RS00705 ENOG4108XIB electron transport protein ysaA GUU87_RS00710 ENOG4105JKW Valine--pyruvate aminotransferase GUU87_RS00715 ENOG4107T9C Alpha amylase catalytic region GUU87_RS00720 ENOG4108UR8 BAX protein GUU87_RS00725 ENOG4105T16 Transcriptional regulator (AraC family) GUU87_RS00730 ENOG4107RNG ABC transporter GUU87_RS00740 ENOG4105DFW ABC transporter GUU87_RS00750 ENOG4105CMG Carbohydrate kinase GUU87_RS00755 ENOG410688U Inner membrane protein yiaB GUU87_RS00760 ENOG4108Z12 YiaAB two helix domain-containing protein GUU87_RS00765 ENOG4105MEV Acyl-transferase GUU87_RS00775 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit GUU87_RS00785 ENOG41060TC Hok gef cell toxic protein GUU87_RS00790 ENOG4105VEQ Cold shock protein GUU87_RS00795 ENOG4105MVF Transcriptional regulator GUU87_RS00800 ENOG4106JH6 (LipO)protein GUU87_RS00810 ENOG4108ZG0 Ompa motb domain protein GUU87_RS00815 ENOG4107QY8 reductase GUU87_RS00820 ENOG4105HNP -acetyltransferase GUU87_RS00825 ENOG4108R3E Dna-3-methyladenine glycosylase i GUU87_RS00830 ENOG4105EAX Putative lipase GUU87_RS00835 ENOG4105FCD Major Facilitator GUU87_RS00840 ENOG4105DIJ Phosphoethanolamine transferase GUU87_RS00855 ENOG4105DEF Extracellular solute-binding protein, family 5 GUU87_RS00860 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GUU87_RS00865 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GUU87_RS00870 ENOG4105C3U ABC transporter GUU87_RS00875 ENOG4108JQ7 (ABC) transporter GUU87_RS00880 ENOG4105C44 Serine transporter GUU87_RS00900 ENOG4105D1V cellulose synthase operon protein YhjU GUU87_RS00905 ENOG4105WQA Cellulose biosynthesis protein BcsF GUU87_RS00910 ENOG4105U74 cellulose biosynthesis protein BcsE GUU87_RS00915 ENOG410661M cytoplasmic protein GUU87_RS00925 ENOG4107QZ7 Cellulose synthase catalytic subunit GUU87_RS00930 ENOG4107EEX Cellulose synthase regulator protein GUU87_RS00935 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) GUU87_RS00940 ENOG4105EJG cellulose synthase GUU87_RS00945 ENOG4105BZU Histidine kinase GUU87_RS00955 ENOG4105CS0 peptidase GUU87_RS00965 ENOG4105CMB EAL domain-containing protein GUU87_RS00970 ENOG41066T0 asmA family GUU87_RS00975 ENOG4105CSH Transporter GUU87_RS00980 ENOG4107H3J ribonuclease GUU87_RS00985 ENOG4105CBN LysR family transcriptional regulator GUU87_RS00990 ENOG4106S2D Transcriptional regulator GUU87_RS01000 ENOG4105CA0 peroxidase GUU87_RS01005 ENOG4105CVK Glutamate decarboxylase GUU87_RS01010 ENOG4108NKV transcriptional regulator GUU87_RS01015 ENOG4105D3F AraC Family Transcriptional Regulator GUU87_RS01020 ENOG4105BZS acriflavin resistance protein GUU87_RS01025 ENOG4105C1P efflux transporter, rnd family, mfp subunit GUU87_RS01035 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci GUU87_RS01040 ENOG4108YK4 Acid-resistance membrane protein GUU87_RS01045 ENOG41060V2 Acid-resistance protein GUU87_RS01050 ENOG4105XXV Acid-resistance protein GUU87_RS01055 ENOG4105KT7 mgtC SapB transporter GUU87_RS01065 ENOG4105F9F transposase GUU87_RS01075 ENOG4105Y4Z Outer Membrane Lipoprotein GUU87_RS01095 ENOG4105K89 arsenate reductase GUU87_RS01100 ENOG4107R5R arsenical pump membrane protein GUU87_RS01105 ENOG4105KBH arsR family transcriptional regulator GUU87_RS01115 ENOG4105DC8 reductase GUU87_RS01120 ENOG4105D6S protein involved in catabolism of external DNA GUU87_RS01125 ENOG4105DGW oligopeptidase A GUU87_RS01130 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) GUU87_RS01135 ENOG4105DUX Transporter GUU87_RS01140 ENOG4108M6U Universal stress protein A GUU87_RS01150 ENOG4105CJ3 phosphate transporter GUU87_RS01155 ENOG4105CBX hi0933 family GUU87_RS01160 ENOG4107UNS conserved inner membrane protein GUU87_RS01175 ENOG4105D0S secretion protein (HlyD GUU87_RS01180 ENOG4105CJ1 ABC, transporter GUU87_RS01185 ENOG4105CMI transporter GUU87_RS01210 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) GUU87_RS01215 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GUU87_RS01220 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GUU87_RS01225 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein GUU87_RS01230 ENOG4107YAK holo-(acyl carrier protein) synthase 2 GUU87_RS01235 ENOG4105DSF transport protein GUU87_RS01240 ENOG4105F9N Major Facilitator Superfamily GUU87_RS01245 ENOG4108W1V Lipoprotein GUU87_RS01250 ENOG4105EX9 Membrane GUU87_RS01265 ENOG4107FS9 Membrane GUU87_RS01275 ENOG4105MG3 Membrane GUU87_RS01280 ENOG4106H78 methyltransferase GUU87_RS01285 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) GUU87_RS01290 ENOG4105CAK Cell division ATP-binding protein ftsE GUU87_RS01295 ENOG4105CRP Part of the ABC transporter FtsEX involved in GUU87_RS01300 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GUU87_RS01305 ENOG4105CP9 extracellular ligand-binding receptor GUU87_RS01320 ENOG4105U59 -acetyltransferase GUU87_RS01325 ENOG4105CP9 extracellular ligand-binding receptor GUU87_RS01330 ENOG4105C32 Amino acid ABC transporter (Permease) GUU87_RS01335 ENOG4105CF8 branched-chain amino acid ABC transporter, permease GUU87_RS01340 ENOG4105C0Z ABC transporter GUU87_RS01345 ENOG4108IV0 ABC, transporter GUU87_RS01355 ENOG4105BZ7 extracellular solute-binding protein family 1 GUU87_RS01360 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component GUU87_RS01365 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component GUU87_RS01370 ENOG4108IJ9 (ABC) transporter GUU87_RS01375 ENOG4107T6V glycerophosphoryl diester phosphodiesterase GUU87_RS01380 ENOG4105WC8 Conserved Protein GUU87_RS01385 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) GUU87_RS01390 ENOG4106FA4 GUU87_RS01405 ENOG4105GMB type VI secretion system effector, hcp1 family GUU87_RS01410 ENOG4105WCN acetyltransferase GUU87_RS01415 ENOG4105D9R oxidoreductase GUU87_RS01420 ENOG4105C2I pirin domain protein GUU87_RS01430 ENOG4105DIQ Transcriptional regulator GUU87_RS01435 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family GUU87_RS01440 ENOG4105C6Z Gluconate GUU87_RS01445 ENOG41076UM multiple antibiotic resistance (MarC)-related protein GUU87_RS01450 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GUU87_RS01475 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) GUU87_RS01500 ENOG4105C6V Glycerol-3-phosphate dehydrogenase GUU87_RS01515 ENOG4105E98 transcriptional regulator DeoR family GUU87_RS01520 ENOG4105CYB regulatoR GUU87_RS01525 ENOG4105E0Y RtcB Protein GUU87_RS01540 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) GUU87_RS01545 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) GUU87_RS01550 ENOG4105C6Z Gluconate GUU87_RS01560 ENOG4105MJ2 Competence protein GUU87_RS01570 ENOG4105DNE Transposase GUU87_RS01580 ENOG4105CE1 Ferrous iron transport protein b GUU87_RS01585 ENOG4105XFK Ferrous iron transport protein A GUU87_RS01590 ENOG4105BZM domain protein GUU87_RS01595 ENOG4108RRZ Transcription elongation factor GreB GUU87_RS01600 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GUU87_RS01605 ENOG4105E0F Histidine kinase GUU87_RS01625 ENOG4108MAJ Membrane GUU87_RS01635 ENOG4105VEJ Heat shock protein GUU87_RS01640 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 GUU87_RS01645 ENOG4105DQY intracellular growth attenuator GUU87_RS01650 ENOG4107RK2 ADP-ribose diphosphatase NudE GUU87_RS01655 ENOG4108JQC penicillin-binding protein 1A GUU87_RS01660 ENOG4108U1Q Pilus assembly protein GUU87_RS01665 ENOG41065NF Fimbrial assembly family protein GUU87_RS01670 ENOG4105XPX DNA utilization protein HofO GUU87_RS01675 ENOG4105ITY Required for the use of extracellular DNA as a nutrient GUU87_RS01680 ENOG4105E4G Type IV pilus GUU87_RS01695 ENOG4105EGB membrane protein DamX GUU87_RS01700 ENOG4105DFE Dna adenine methylase GUU87_RS01705 ENOG4105DJV ribulose-phosphate 3-epimerase GUU87_RS01710 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) GUU87_RS01715 ENOG4105C31 Tryptophanyl-tRNA synthetase GUU87_RS01720 ENOG4108M21 GUU87_RS01725 ENOG4105RMW regulation of transcription, DNA-dependent GUU87_RS01730 ENOG4108626 Racemase GUU87_RS01735 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) GUU87_RS01740 ENOG41080QX K07048 phosphotriesterase-related protein GUU87_RS01745 ENOG4105MUZ Protein of unknown function DUF2620 GUU87_RS01750 ENOG4106M0N transport system permease protein GUU87_RS01755 ENOG4106PKC pyridoxal phosphate binding GUU87_RS01760 ENOG4105FDP GntR family transcriptional regulator GUU87_RS01765 ENOG4108KPW sugar kinase GUU87_RS01770 ENOG4107Y0V Not clear, may be involved in an isomerization step GUU87_RS01775 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine GUU87_RS01780 ENOG4107QHQ amino acid GUU87_RS01785 ENOG4105VYH GUU87_RS01795 ENOG4107V9H nitrite transporter GUU87_RS01800 ENOG4105WZK nitrite reductase NADPH small subunit GUU87_RS01805 ENOG4107QZF nitrite reductase NADPH large subunit GUU87_RS01815 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) GUU87_RS01820 ENOG4106195 uncharacterized protein yhfG GUU87_RS01825 ENOG4105MZU cell filamentation protein GUU87_RS01830 ENOG4105DDQ anthranilate synthase GUU87_RS01835 ENOG4105C8Y Acetylornithine aminotransferase GUU87_RS01840 ENOG410613R integral membrane protein, YccS YhfK family GUU87_RS01845 ENOG4107RYR Transcriptional regulator, Crp Fnr family GUU87_RS01850 ENOG4108UKZ OsmC family GUU87_RS01855 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) GUU87_RS01865 ENOG4105DNZ Alpha Beta Hydrolase GUU87_RS01870 ENOG4105C5H ABC transporter GUU87_RS01885 ENOG4105VKU nucleicacid-binding protein GUU87_RS01890 ENOG4108YZY peptidylprolyl cis-trans isomerase GUU87_RS01900 ENOG4108V1T peptidylprolyl cis-trans isomerase GUU87_RS01905 ENOG4105WWK YheO domain protein GUU87_RS01945 ENOG4105W53 bacterioferritin-associated ferredoxin GUU87_RS01950 ENOG4108UQY Iron-storage protein GUU87_RS01970 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) GUU87_RS01975 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) GUU87_RS01985 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) GUU87_RS01990 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) GUU87_RS01995 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) GUU87_RS02000 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) GUU87_RS02010 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal GUU87_RS02020 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) GUU87_RS02035 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) GUU87_RS02045 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) GUU87_RS02050 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) GUU87_RS02060 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) GUU87_RS02065 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) GUU87_RS02070 ENOG41067V7 50S ribosomal protein L36 GUU87_RS02075 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits GUU87_RS02085 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) GUU87_RS02090 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) GUU87_RS02100 ENOG4105VTS DnaJ-like, subfamily C GUU87_RS02105 ENOG4105W1Y Transcriptional regulator GUU87_RS02110 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system GUU87_RS02120 ENOG4105C1A potassium transporter peripheral membrane GUU87_RS02140 ENOG4105C79 DNA protecting protein DprA GUU87_RS02150 ENOG4108WI1 Dna topoisomerase GUU87_RS02165 ENOG4105SG3 Protein of unknown function (DUF1488) GUU87_RS02170 ENOG4108Z0R Transferase GUU87_RS02210 ENOG4105CDA abc transporter atp-binding protein GUU87_RS02215 ENOG4105DRP amino acid AbC transporter GUU87_RS02220 ENOG4105EZ7 amino acid ABC transporter GUU87_RS02230 ENOG4105XCM membrane LIPOPROTEIN GUU87_RS02235 ENOG4105BZS acriflavin resistance protein GUU87_RS02240 ENOG4105C1P efflux transporter, rnd family, mfp subunit GUU87_RS02245 ENOG4108XG4 DNA-binding transcriptional regulator GUU87_RS02250 ENOG41061ME transport protein GUU87_RS02255 ENOG4105CEC DNA methylase N-4 N-6 GUU87_RS02260 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) GUU87_RS02265 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GUU87_RS02275 ENOG4108IA2 Sodium pantothenate symporter GUU87_RS02280 ENOG4105RG0 Membrane GUU87_RS02285 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase GUU87_RS02290 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein GUU87_RS02295 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family GUU87_RS02300 ENOG41062P1 Diguanylate cyclase phosphodiesterase GUU87_RS02305 ENOG4105DFF Rod shape-determining protein mreb GUU87_RS02310 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) GUU87_RS02315 ENOG4105VQ7 Rod shape-determining protein MreD GUU87_RS02325 ENOG4105C03 ribonuclease GUU87_RS02330 ENOG4105QD6 exported protein GUU87_RS02335 ENOG4105D1U peptidase U62 modulator of DNA gyrase GUU87_RS02340 ENOG4105CR8 Transcriptional regulator GUU87_RS02360 ENOG4105UNR (Barnase) inhibitor GUU87_RS02365 ENOG4105RID UPF0379 protein yhcN GUU87_RS02380 ENOG4105C0H protease GUU87_RS02385 ENOG4105C0H protease GUU87_RS02390 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III GUU87_RS02395 ENOG4105D6Z AFG1 family ATPase GUU87_RS02405 ENOG4108UJD 30S ribosomal protein S9 GUU87_RS02410 ENOG4107MKT Stringent starvation protein a GUU87_RS02415 ENOG4105KB2 stringent starvation protein b GUU87_RS02420 ENOG4105CEE C4-dicarboxylate transporter GUU87_RS02450 ENOG4108R66 Conserved Protein GUU87_RS02455 ENOG4105DFS Conserved Protein GUU87_RS02460 ENOG4105BZ8 glutamate synthase GUU87_RS02465 ENOG4105CBC glutamate synthase GUU87_RS02470 ENOG4105N5T Radical SAM Protein GUU87_RS02475 ENOG4105BZU Histidine kinase GUU87_RS02480 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain GUU87_RS02490 ENOG4108NIH transferase activity, transferring phosphorus-containing groups GUU87_RS02495 ENOG41080Z8 PHOSPHOCARRIER protein GUU87_RS02505 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN GUU87_RS02510 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA GUU87_RS02515 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GUU87_RS02520 ENOG4108IUZ ABC transporter GUU87_RS02525 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA GUU87_RS02530 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) GUU87_RS02535 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase GUU87_RS02540 ENOG4105C2X Arabinose 5-phosphate isomerase GUU87_RS02545 ENOG4105FEU K -dependent Na -Ca exchanger GUU87_RS02550 ENOG4105DHJ ABC, transporter GUU87_RS02555 ENOG4105CY3 ABC transporter, permease GUU87_RS02560 ENOG4107PE3 Mammalian cell entry related domain protein GUU87_RS02565 ENOG4105E3I toluene tolerance GUU87_RS02570 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane GUU87_RS02575 ENOG4105VFK BolA family GUU87_RS02585 ENOG4105HVQ Regulatory factor of maltose metabolism GUU87_RS02590 ENOG4105EAH synthase GUU87_RS02605 ENOG4105QYV Membrane GUU87_RS02615 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase GUU87_RS02620 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) GUU87_RS02625 ENOG4105HBR Rna-binding protein GUU87_RS02630 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) GUU87_RS02635 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GUU87_RS02640 ENOG4105EEI dihydropteroate synthase GUU87_RS02660 ENOG4105DIJ Phosphoethanolamine transferase GUU87_RS02680 ENOG4105CHV Transcription elongation factor NusA GUU87_RS02695 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) GUU87_RS02710 ENOG4105RT1 May be involved in cell division (By similarity) GUU87_RS02720 ENOG4105C1J atp-dependent rna helicase GUU87_RS02725 ENOG4105CIC tryptophan-specific transport protein GUU87_RS02735 ENOG4105DEN Luciferase family GUU87_RS02740 ENOG4106RZ4 Peptidase U32 GUU87_RS02745 ENOG4105CFP Peptidase U32 GUU87_RS02750 ENOG4105XPQ lipid carrier protein GUU87_RS02755 ENOG4108YYD acetyltransferase GUU87_RS02770 ENOG4107R7Y intracellular protease Pfpi family GUU87_RS02775 ENOG4105K4T epimerase GUU87_RS02780 ENOG4107S21 permease GUU87_RS02785 ENOG4105W4M Transport-associated protein GUU87_RS02805 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) GUU87_RS02810 ENOG4105I74 Fimbrial protein GUU87_RS02815 ENOG4105I74 Fimbrial protein GUU87_RS02820 ENOG4105CW0 outer membrane usher protein GUU87_RS02825 ENOG4108VCD Chaperone GUU87_RS02830 ENOG4105Q10 Fimbrial-like protein GUU87_RS02835 ENOG4106HBN Galactosamine-6-phosphate isomerase GUU87_RS02840 ENOG4105F3R pts system mannose fructose sorbose family iid GUU87_RS02845 ENOG4105ETZ PTS System GUU87_RS02850 ENOG4108UZY PTS System GUU87_RS02860 ENOG4105E70 isomerase GUU87_RS02865 ENOG4105CE4 GlcNAc 6-P deacetylase GUU87_RS02870 ENOG4108YTN IIa component GUU87_RS02875 ENOG4105F3R pts system mannose fructose sorbose family iid GUU87_RS02885 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB GUU87_RS02895 ENOG4105E98 transcriptional regulator DeoR family GUU87_RS02900 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression GUU87_RS02905 ENOG4105ZEG Suppressor protein GUU87_RS02910 ENOG4105CTX dehydratase GUU87_RS02915 ENOG4105DJB Major Facilitator Superfamily GUU87_RS02925 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GUU87_RS02930 ENOG4105BZW Glycerate kinase GUU87_RS02955 ENOG410811B TRANSCRIPTIONal GUU87_RS02960 ENOG4105C7B Threonine dehydratase GUU87_RS02970 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) GUU87_RS02975 ENOG4105C6N Formate acetyltransferase GUU87_RS02980 ENOG4105KME endoribonuclease L-psp GUU87_RS02985 ENOG4105EJQ L-serine dehydratase GUU87_RS02990 ENOG4105C44 Serine transporter GUU87_RS03000 ENOG4106D80 Uncharacterized protein YhaL GUU87_RS03005 ENOG4108CNN domain protein GUU87_RS03010 ENOG4105CWB LysR family transcriptional Regulator GUU87_RS03015 ENOG4105KAF membrAne GUU87_RS03020 ENOG4105KAF membrAne GUU87_RS03025 ENOG4105CHF Glutathione S-transferase GUU87_RS03030 ENOG4108VBZ doxx family GUU87_RS03035 ENOG4105YJD GUU87_RS03040 ENOG41090KG Inner membrane protein YqjE GUU87_RS03045 ENOG4105NE1 Conserved Protein GUU87_RS03050 ENOG4105WAY exported protein GUU87_RS03055 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) GUU87_RS03060 ENOG4106W5V Membrane GUU87_RS03065 ENOG4107YCY Transcriptional regulator GUU87_RS03090 ENOG4105DPW Major facilitator superfamily MFS_1 GUU87_RS03100 ENOG4105CTX dehydratase GUU87_RS03105 ENOG4105P66 Membrane GUU87_RS03110 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) GUU87_RS03115 ENOG4105DU1 integral membrane protein, terc GUU87_RS03120 ENOG4105EE0 oxidoreductase GUU87_RS03125 ENOG4108UB4 uncharacterized protein ygjQ GUU87_RS03130 ENOG4108VKG metal-dependent hydrolase GUU87_RS03145 ENOG4108Z3N Transcriptional regulator GUU87_RS03150 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GUU87_RS03155 ENOG4107WCA isomerase GUU87_RS03160 ENOG4107W6W Conserved Protein GUU87_RS03165 ENOG4105E5D amino acid GUU87_RS03170 ENOG4105FK9 beta-D-galactosidase beta subunit GUU87_RS03175 ENOG4105CNT hydrolase family 2 GUU87_RS03180 ENOG4105CQ4 Transcriptional regulator GUU87_RS03185 ENOG4108Y51 tRNA-binding protein GUU87_RS03195 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor GUU87_RS03200 ENOG4105NTW Transcriptional regulator GUU87_RS03205 ENOG4105Q26 Siderophore-interacting protein GUU87_RS03220 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GUU87_RS03225 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) GUU87_RS03230 ENOG4105VCC 30S ribosomal protein S21 GUU87_RS03240 ENOG4107QPK )-transporter GUU87_RS03245 ENOG4107GFK fumarate GUU87_RS03250 ENOG4106DSS Tartrate dehydratase subunit alpha GUU87_RS03255 ENOG4105EJC lysr family transcriptional regulator GUU87_RS03265 ENOG4107ZVW dihydroneopterin aldolase GUU87_RS03280 ENOG4106MWK domain protein GUU87_RS03285 ENOG4105I7R Adenylate cyclase GUU87_RS03310 ENOG4107S78 Band 7 protein GUU87_RS03315 ENOG4105PV3 Inner membrane protein yqiJ GUU87_RS03325 ENOG4108MY7 Fimbrial GUU87_RS03330 ENOG4108TTM chaperone GUU87_RS03340 ENOG4105H8W Fimbrial protein GUU87_RS03345 ENOG4105W0Z cytoplasmic protein GUU87_RS03365 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b GUU87_RS03370 ENOG4106032 Glutathionylspermidine synthase GUU87_RS03380 ENOG4105DFG type I secretion outer membrane protein GUU87_RS03385 ENOG41087AY ADP-Ribose pyrophosphatase GUU87_RS03390 ENOG4108SX3 cytoplasmic protein GUU87_RS03395 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) GUU87_RS03400 ENOG4105IPS esterase GUU87_RS03405 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GUU87_RS03425 ENOG4108RVA ribokinase GUU87_RS03445 ENOG4105CT4 transporter GUU87_RS03450 ENOG4105VRH Antibiotic biosynthesis monooxygenase GUU87_RS03455 ENOG4105NF4 modulator of drug activity GUU87_RS03460 ENOG4107DEU Inner membrane protein YgiZ GUU87_RS03465 ENOG4105DHQ Histidine kinase GUU87_RS03470 ENOG4105XJC Two component transcriptional regulator (Winged helix family GUU87_RS03475 ENOG4105H4F exported protein GUU87_RS03480 ENOG4105F4I Transcriptional regulator GUU87_RS03485 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GUU87_RS03490 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase GUU87_RS03495 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) GUU87_RS03500 ENOG4105CCT upf0313 protein GUU87_RS03510 ENOG4105ZKC Conserved Protein GUU87_RS03515 ENOG4105CV8 reductase GUU87_RS03520 ENOG4108I6A alcohol dehydrogenase GUU87_RS03525 ENOG4105CF7 AraC family transcriptional regulator GUU87_RS03530 ENOG4108K81 inner membrane protein YghB GUU87_RS03535 ENOG4105C28 cystathionine GUU87_RS03540 ENOG4105CWK Biopolymer transport protein, ExbB GUU87_RS03545 ENOG4108ZZF transport protein (ExbD) GUU87_RS03550 ENOG4105CYX Short-chain dehydrogenase reductase Sdr GUU87_RS03560 ENOG4105CPC Aldo Keto reductase GUU87_RS03570 ENOG410900S Protein of unknown function (DUF2623) GUU87_RS03575 ENOG4105E3S small subunit GUU87_RS03580 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GUU87_RS03585 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit GUU87_RS03590 ENOG4105DPX Hydrogenase, large subunit GUU87_RS03595 ENOG4108USZ hydrogenase GUU87_RS03600 ENOG4108WGS hydrogenase 2-specific chaperone GUU87_RS03605 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) GUU87_RS03610 ENOG41082MF Hydrogenase assembly chaperone hypC hupF GUU87_RS03620 ENOG4105CYM Glutathione S-transferase GUU87_RS03625 ENOG4106032 Glutathionylspermidine synthase GUU87_RS03630 ENOG4105CJ3 phosphate transporter GUU87_RS03635 ENOG4105F9F transposase GUU87_RS03645 ENOG4108GH0 ATP-binding protein yghT GUU87_RS03650 ENOG4108NDC ATP-binding protein yghS GUU87_RS03655 ENOG4106FPV ATP-binding protein YghR GUU87_RS03660 ENOG4108S55 polysaccharide biosynthesis protein GUU87_RS03670 ENOG4108UUE Transcriptional regulator GUU87_RS03675 ENOG4108M8S permease YjgP YjgQ family protein GUU87_RS03685 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) GUU87_RS03690 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GUU87_RS03700 ENOG4107RCI amp-dependent synthetase and ligase GUU87_RS03710 ENOG4108KWP DNA-binding transcriptional regulator GlcC GUU87_RS03715 ENOG4105CQB FAD linked oxidase domain protein GUU87_RS03720 ENOG4105EU8 FAD linked oxidase domain protein GUU87_RS03725 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GUU87_RS03730 ENOG4108ZJF Glcg protein GUU87_RS03735 ENOG4107QP3 malate synthase g GUU87_RS03740 ENOG4105DAA L-lactate GUU87_RS03745 ENOG4105F88 accessory colonization factor AcfD GUU87_RS03770 ENOG4107QHF type ii secretion system protein e GUU87_RS03775 ENOG4105D7Q type ii secretion system GUU87_RS03780 ENOG4108VAU general secretion pathway protein G GUU87_RS03790 ENOG4105X5Z General secretion pathway protein I GUU87_RS03810 ENOG4105U1E general secretion pathway protein M GUU87_RS03835 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles GUU87_RS03840 ENOG4106WJE Protein of unknown function (DUF987) GUU87_RS03845 ENOG4108YGG dna repair protein GUU87_RS03850 ENOG4106549 Antirestriction protein GUU87_RS03855 ENOG4106H6R UPF0380 protein GUU87_RS03860 ENOG4105F4K antigen 43 GUU87_RS03890 ENOG4105KF5 hemolysin expression-modulating protein GUU87_RS03910 ENOG4105M71 acetolactate synthase 1 regulatory subunit GUU87_RS03915 ENOG4107FB0 transcriptional regulator DeoR family GUU87_RS03920 ENOG4108RVA ribokinase GUU87_RS03925 ENOG4105EDR glucose galactose transporter GUU87_RS03935 ENOG4108ZQS transposase GUU87_RS03945 ENOG4105CXY transporter GUU87_RS03950 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC GUU87_RS03960 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta GUU87_RS03975 ENOG4105HMV Fimbrial protein GUU87_RS03980 ENOG4108ZJG MrfB protein GUU87_RS03985 ENOG4106PG1 outer membrane usher protein GUU87_RS03990 ENOG4106P2F Pfam:Pili_assembly_C GUU87_RS04010 ENOG4105CXC rtn protein GUU87_RS04030 ENOG4108UQV Membrane GUU87_RS04035 ENOG4105CXN decarboxylase GUU87_RS04040 ENOG4105EAA nucleoside GUU87_RS04055 ENOG4105CEN a g-specific adenine glycosylase GUU87_RS04065 ENOG41090ED Protein with unknown function (DUF469) GUU87_RS04070 ENOG4105K33 Periplasmic Protein GUU87_RS04075 ENOG4105HDK L-asparaginase GUU87_RS04080 ENOG4106MH3 alpha helix chain GUU87_RS04085 ENOG4105CSA Coproporphyrinogen iii oxidase GUU87_RS04090 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) GUU87_RS04100 ENOG4108VIA integral membrane protein GUU87_RS04105 ENOG4105DFA alanine racemase domain protein GUU87_RS04110 ENOG4105CZX twitching motility protein GUU87_RS04130 ENOG4105D7Z glutathione synthase GUU87_RS04135 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) GUU87_RS04140 ENOG4105RWS endonuclease I GUU87_RS04150 ENOG4107QNK )-transporter GUU87_RS04170 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) GUU87_RS04185 ENOG4108K0D peptidase, M48 GUU87_RS04190 ENOG4105CV1 Transketolase (EC 2.2.1.1) GUU87_RS04195 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia GUU87_RS04200 ENOG4105CTS PTS system mannitol-specific GUU87_RS04205 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein GUU87_RS04210 ENOG4108Q8A Fructose-1,6-bisphosphatase GUU87_RS04215 ENOG4108R4K DNA-binding, transcriptional regulator GUU87_RS04220 ENOG4107Z1W Fructose transport system kinase GUU87_RS04225 ENOG4108JJB ABC transporter GUU87_RS04230 ENOG4108JJB ABC transporter GUU87_RS04260 ENOG4105D2N Aldolase GUU87_RS04265 ENOG4105D64 Mechanosensitive ion channel GUU87_RS04270 ENOG4108ZUB Lysine exporter protein (Lyse ygga) GUU87_RS04275 ENOG4105MPN Membrane GUU87_RS04280 ENOG4105DEQ transcriptional regulator GUU87_RS04285 ENOG4105CYC Transferase GUU87_RS04290 ENOG4108M7F enoyl-CoA hydratase isomerase GUU87_RS04295 ENOG4105DJT lAO AO transport system ATPase GUU87_RS04300 ENOG4105D5P Methylmalonyl-coA mutase GUU87_RS04320 ENOG4108JQ1 Dehydrogenase GUU87_RS04335 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase GUU87_RS04355 ENOG4107RAQ aminopeptidase GUU87_RS04360 ENOG4105D0A hydroxylase GUU87_RS04365 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family GUU87_RS04385 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor GUU87_RS04390 ENOG4105CYX Short-chain dehydrogenase reductase Sdr GUU87_RS04395 ENOG4105CS2 ec 3.2.1.21 GUU87_RS04405 ENOG4108UT2 hemolysin iii GUU87_RS04415 ENOG4105Y75 tpr repeat protein GUU87_RS04420 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB GUU87_RS04425 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) GUU87_RS04430 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GUU87_RS04435 ENOG4105T95 Thiol disulfide interChange protein GUU87_RS04440 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) GUU87_RS04450 ENOG4105CRK lysyL-tRNA synthetase GUU87_RS04470 ENOG4105C2W permease GUU87_RS04475 ENOG4105BZ8 glutamate synthase GUU87_RS04480 ENOG4108R8B oxidoreductase Fe-S subunit GUU87_RS04485 ENOG4105C7N Xanthine uracil vitamin C permease GUU87_RS04490 ENOG4107QUY Guanine deaminase GUU87_RS04495 ENOG4105C2W permease GUU87_RS04500 ENOG4105C7W Xanthine dehydrogenase GUU87_RS04505 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase GUU87_RS04510 ENOG4107UUR Chlorohydrolase aminohydrolase GUU87_RS04515 ENOG4105BZ8 glutamate synthase GUU87_RS04520 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase GUU87_RS04525 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC GUU87_RS04530 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family GUU87_RS04535 ENOG4105C5B carbamate kinase GUU87_RS04545 ENOG4107S4Y M20 DapE family protein YgeY GUU87_RS04550 ENOG4107RCH Diaminopropionate ammonia-lyase GUU87_RS04555 ENOG4105IW6 Carbamoyltransferase GUU87_RS04560 ENOG4108JUB Transcriptional regulator GUU87_RS04565 ENOG4108UTP (2Fe-2S)-binding domain protein GUU87_RS04570 ENOG4108HR6 Dehydrogenase GUU87_RS04575 ENOG4105C7W Xanthine dehydrogenase GUU87_RS04580 ENOG4108K5P (LipO)protein GUU87_RS04590 ENOG4108T88 GUU87_RS04605 ENOG41075IY surface presentation of antigens protein SpaP GUU87_RS04615 ENOG4108TN6 type iii secretion GUU87_RS04620 ENOG4108M6W surface presentation of antigens protein SpaS GUU87_RS04625 ENOG4108M6W surface presentation of antigens protein SpaS GUU87_RS04640 ENOG4108RC9 Type III secretion system protein GUU87_RS04655 ENOG4108RBT type iii secretion GUU87_RS04685 ENOG4108YAB Invasion protein GUU87_RS04710 ENOG4105FV3 GUU87_RS04715 ENOG4108TC1 Transcriptional regulator GUU87_RS04720 ENOG4105ISV protein with bipartite regulator domain GUU87_RS04725 ENOG4108MHD transport protein GUU87_RS04730 ENOG4105CHU acetyl-coa acetyltransferase GUU87_RS04740 ENOG4105CHR reductase GUU87_RS04745 ENOG4107QNK )-transporter GUU87_RS04755 ENOG4105RQF LysR family Transcriptional regulator GUU87_RS04760 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) GUU87_RS04765 ENOG41060NJ transcriptional regulator GUU87_RS04780 ENOG4105CPC Aldo Keto reductase GUU87_RS04785 ENOG4105SUV lipoprotein YgdR GUU87_RS04790 ENOG4105EE5 Membrane protein terC GUU87_RS04805 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase GUU87_RS04820 ENOG4105IPU prepilin peptidase dependent protein A GUU87_RS04825 ENOG4105JCS prepilin peptidase dependent protein GUU87_RS04830 ENOG4105SEN Protein of unknown function (DUF2509) GUU87_RS04835 ENOG4105RVB Prepilin peptidase dependent protein c GUU87_RS04840 ENOG4105DSY exodeoxyribonuclease V, gamma GUU87_RS04845 ENOG4107QXK peptidase GUU87_RS04850 ENOG4107QKA exodeoxyribonuclease V beta GUU87_RS04855 ENOG4107QYX exodeoxyribonuclease v alpha GUU87_RS04860 ENOG4107QZM n-acetylglutamate synthase GUU87_RS04865 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GUU87_RS04885 ENOG4105CA3 membrane-bound lytic murein transglycosylase GUU87_RS04890 ENOG4105CUZ uba thif-type nad fad binding protein GUU87_RS04895 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) GUU87_RS04900 ENOG4105C9B Cysteine desulfurase GUU87_RS04905 ENOG4105M5B (LipO)protein GUU87_RS04910 ENOG4105ETT transcriptional Regulator, LysR family GUU87_RS04915 ENOG4105M08 Membrane GUU87_RS04925 ENOG4107EDW L-fucose operon activator GUU87_RS04935 ENOG4105CMG Carbohydrate kinase GUU87_RS04945 ENOG4105EDR glucose galactose transporter GUU87_RS04950 ENOG4107W7X Aldolase GUU87_RS04955 ENOG4105C0A alcohol dehydrogenase GUU87_RS04965 ENOG4105EJQ L-serine dehydratase GUU87_RS04970 ENOG4105C44 Serine transporter GUU87_RS04975 ENOG4105EWT decarboxylase family GUU87_RS04990 ENOG4105WP7 tRNA pseudouridine synthase C GUU87_RS04995 ENOG4105DR9 pseudouridine synthase GUU87_RS05000 ENOG4105QDK Flavodoxin GUU87_RS05005 ENOG4105DJB Major Facilitator Superfamily GUU87_RS05010 ENOG4105EQX glucarate dehydratase GUU87_RS05015 ENOG4105EQX glucarate dehydratase GUU87_RS05020 ENOG4105BZU Histidine kinase GUU87_RS05030 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) GUU87_RS05035 ENOG4106A2Z transcriptional regulator antitoxin, MazE GUU87_RS05040 ENOG4105MZG transcriptional modulator of maze toxin, mazf GUU87_RS05045 ENOG4105DXN mazG family GUU87_RS05065 ENOG4105HA9 of methanol dehydrogenase type GUU87_RS05075 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) GUU87_RS05085 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase GUU87_RS05105 ENOG4107635 Hok Gef family protein GUU87_RS05110 ENOG4105DTT CRISPR-associated helicase, cas3 GUU87_RS05125 ENOG41060M0 Crispr-associated protein, cse4 family GUU87_RS05130 ENOG4108VWQ crispr-associated protein GUU87_RS05140 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) GUU87_RS05145 ENOG4105PWE CRISPR-associated protein cas2 GUU87_RS05150 ENOG4108MXK alkaline phosphatase isozyme conversion GUU87_RS05170 ENOG4105N0Z inner membrane protein ygbE GUU87_RS05205 ENOG4108K5P (LipO)protein GUU87_RS05210 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GUU87_RS05220 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase GUU87_RS05225 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) GUU87_RS05230 ENOG4105KZM cytoplasmic protein GUU87_RS05235 ENOG4105C6Z Gluconate GUU87_RS05240 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) GUU87_RS05245 ENOG4105FB2 class II Aldolase GUU87_RS05250 ENOG4105G63 Type III effector Hrp-dependent GUU87_RS05255 ENOG4105ZXK Dehydrogenase GUU87_RS05260 ENOG4105MVE transcriptional regulator GUU87_RS05265 ENOG4105MEW serine threonine protein phosphatase GUU87_RS05270 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) GUU87_RS05280 ENOG4105VXR cytoplasmic protein GUU87_RS05285 ENOG4108JUA Transcriptional regulator GUU87_RS05290 ENOG4105C45 hydrogenase expression formation protein (HypE) GUU87_RS05295 ENOG4105CQS hydrogenase expression formation protein HypD GUU87_RS05300 ENOG41083WG hydrogenase assembly chaperone GUU87_RS05305 ENOG4107RSS Hydrogenase accessory protein HypB GUU87_RS05310 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) GUU87_RS05315 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA GUU87_RS05320 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) GUU87_RS05325 ENOG4107R30 NADH dehydrogenase GUU87_RS05330 ENOG4107TDF Formate hydrogenlyase subunit 4 GUU87_RS05335 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GUU87_RS05340 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit GUU87_RS05345 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit GUU87_RS05350 ENOG4105I6X formate hydrogenlyase maturation GUU87_RS05355 ENOG4108MG9 hydrogenase 3 maturation protease GUU87_RS05360 ENOG4105CS2 ec 3.2.1.21 GUU87_RS05365 ENOG4105C5Y PTS System GUU87_RS05370 ENOG4105DDV Transcriptional regulator (LacI family GUU87_RS05375 ENOG4108RC0 Electron transport protein GUU87_RS05380 ENOG4105C8H hydrogenase maturation protein Hypf GUU87_RS05395 ENOG4108JUA Transcriptional regulator GUU87_RS05405 ENOG410804X Transcriptional regulator GUU87_RS05410 ENOG4105J92 DNA-binding transcriptional activator GutM GUU87_RS05415 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase GUU87_RS05420 ENOG4105VI0 Pts system, glucitol sorbitol-specific GUU87_RS05425 ENOG4105DZY Pts system, glucitol sorbitol-specific GUU87_RS05430 ENOG410787A Pts system, glucitol sorbitol-specific GUU87_RS05435 ENOG4105CVE Lytic murein transglycosylase GUU87_RS05440 ENOG4107TH8 cina domain protein GUU87_RS05460 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) GUU87_RS05490 ENOG4107VXZ Hydrolase GUU87_RS05495 ENOG4105W39 Membrane GUU87_RS05510 ENOG4105C0R drug resistance transporter emrb qaca subfamily GUU87_RS05515 ENOG4105CW7 secretion protein, HlyD family GUU87_RS05520 ENOG4105NTK Transcriptional repressor Mpra GUU87_RS05525 ENOG4105ZED uncharacterized protein ygaH GUU87_RS05530 ENOG4108UMN azlc family GUU87_RS05540 ENOG4105GIJ Glycine betaine GUU87_RS05545 ENOG4108HQS Glycine betaine GUU87_RS05550 ENOG4108IJ7 Glycine betaine GUU87_RS05555 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GUU87_RS05560 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GUU87_RS05565 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) GUU87_RS05570 ENOG4105WAZ (Glutaredoxin-like protein) NrdH GUU87_RS05575 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) GUU87_RS05580 ENOG4108WMJ Protein of unknown function (DUF2002) GUU87_RS05585 ENOG4108RNS Exports L-alanine (By similarity) GUU87_RS05590 ENOG4108X73 DNA- binding protein GUU87_RS05595 ENOG4108V62 Rhodanese domain protein GUU87_RS05600 ENOG41080HT Transcriptional regulator, arsr family GUU87_RS05605 ENOG4105VPI YqaE family transport protein GUU87_RS05610 ENOG4109066 lysm domain bon superfamily protein GUU87_RS05615 ENOG4108PVQ transcriptional regulator GUU87_RS05620 ENOG4105C85 amino acid GUU87_RS05625 ENOG4108JPW Aminotransferase GUU87_RS05630 ENOG4105C26 Dehydrogenase GUU87_RS05635 ENOG4105D5U fad dependent oxidoreductase GUU87_RS05645 ENOG4105E54 alpha-amylase GUU87_RS05700 ENOG4105F9F transposase GUU87_RS05730 ENOG4105DFP Integrase GUU87_RS05745 ENOG4108Z1B Cyclase dehydrase GUU87_RS05750 ENOG4105VDB UPF0125 protein GUU87_RS05755 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) GUU87_RS05760 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) GUU87_RS05775 ENOG4108JU6 CBS domain protein GUU87_RS05780 ENOG4106KVJ cytochrome C assembly protein GUU87_RS05785 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY GUU87_RS05810 ENOG41090EK ompa motb domain protein GUU87_RS05815 ENOG4108KHX Diguanylate cyclase GUU87_RS05820 ENOG4108WS1 GUU87_RS05825 ENOG4105QP9 Protein of unknown function (DUF2799) GUU87_RS05830 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GUU87_RS05835 ENOG4105EHE chorismate mutase- prephenate dehydrogenase GUU87_RS05840 ENOG4105CQC Prephenate dehydratase GUU87_RS05850 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA GUU87_RS05855 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane GUU87_RS05860 ENOG4105C34 Pseudouridine synthase GUU87_RS05865 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase GUU87_RS05870 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GUU87_RS05895 ENOG4105CSH Transporter GUU87_RS05900 ENOG4105T42 (LipO)protein GUU87_RS05905 ENOG4105JIM Phosphatidylserine synthase GUU87_RS05910 ENOG4105CD5 CoA-binding domain protein GUU87_RS05915 ENOG4106IUH DTW domain containing protein GUU87_RS05920 ENOG4105K63 Thioredoxin GUU87_RS05925 ENOG4105EIB trna rrna methyltransferase GUU87_RS05945 ENOG41090KR LysR family transcriptional Regulator GUU87_RS05950 ENOG4105C1J atp-dependent rna helicase GUU87_RS05960 ENOG4108IYU L-aspartate oxidase GUU87_RS05970 ENOG4105EMN RNA polymerase sigma factor GUU87_RS05975 ENOG41069PW sigma-e factor negative regulatory protein GUU87_RS05980 ENOG4105VQK sigma E regulatory protein, MucB RseB GUU87_RS05985 ENOG4105WMJ Positive regulator of sigma E, RseC MucC GUU87_RS05995 ENOG4105C3F Signal peptidase i GUU87_RS06015 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) GUU87_RS06030 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding GUU87_RS06035 ENOG4106G6Q Transcriptional regulator GUU87_RS06040 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB GUU87_RS06045 ENOG4108Z6B deaminase GUU87_RS06060 ENOG4107WP9 Histidine kinase GUU87_RS06065 ENOG4108SKK alpha helix protein GUU87_RS06070 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GUU87_RS06075 ENOG4108YZA Nitrogen regulatory protein pii GUU87_RS06080 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GUU87_RS06090 ENOG4108NZE NAGC-like transcriptional regulator GUU87_RS06095 ENOG4107HQ7 repeat protein GUU87_RS06100 ENOG4105FCA ABC transporter periplasmic-binding protein YphF GUU87_RS06105 ENOG4108F37 ATP-binding component of a transport system GUU87_RS06110 ENOG4105CNN ABC, transporter GUU87_RS06115 ENOG4105CPQ Dehydrogenase GUU87_RS06120 ENOG4108ZKT aldose 1-epimerase GUU87_RS06125 ENOG4108SB3 DoxX Family GUU87_RS06150 ENOG4105FUY alpha subunit GUU87_RS06155 ENOG4108W5M transcriptional regulator GUU87_RS06160 ENOG4105D8G Major Facilitator superfamily GUU87_RS06165 ENOG4108MN2 Stationary phase inducible protein CsiE GUU87_RS06170 ENOG4107XM9 (LipO)protein GUU87_RS06180 ENOG4105CVS RNA methyltransferase TrmH family, group 1 GUU87_RS06195 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins GUU87_RS06215 ENOG4108ZIT Ferredoxin, 2FE-2S GUU87_RS06220 ENOG4105WVQ Fe-S assembly protein IscX GUU87_RS06230 ENOG4105YYA enhanced serine sensitivity protein SseB GUU87_RS06235 ENOG4105KHC sulfurtransferase GUU87_RS06240 ENOG4105DN3 alpha-2-macroglobulin domain protein GUU87_RS06245 ENOG4108JQB penicillin-binding protein 1C GUU87_RS06275 ENOG4105N21 Membrane GUU87_RS06290 ENOG4105VPD cellular component movement GUU87_RS06300 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) GUU87_RS06310 ENOG41066DY Membrane GUU87_RS06315 ENOG4108ZMA Outer membrane lipoprotein GUU87_RS06320 ENOG41062G3 Protein of unknown function (DUF2633) GUU87_RS06325 ENOG4105BZU Histidine kinase GUU87_RS06330 ENOG4105C9X ppx gppa phosphatase GUU87_RS06335 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) GUU87_RS06340 ENOG4108V3E phosphoribosylglycinamide formyltransferase GUU87_RS06355 ENOG4105C2W permease GUU87_RS06365 ENOG4105K89 arsenate reductase GUU87_RS06370 ENOG4105ERG peptidase m48, ste24p GUU87_RS06375 ENOG4105C02 permease GUU87_RS06390 ENOG4105I6X formate hydrogenlyase maturation GUU87_RS06405 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GUU87_RS06410 ENOG4108JPZ Monovalent cation H antiporter subunit D GUU87_RS06415 ENOG4107WQX hydrogenase 4 membrane subunit GUU87_RS06425 ENOG4107TDF Formate hydrogenlyase subunit 4 GUU87_RS06430 ENOG4108JPZ Monovalent cation H antiporter subunit D GUU87_RS06435 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) GUU87_RS06440 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GUU87_RS06445 ENOG4105RH4 Glycine cleavage system transcriptional repressor GUU87_RS06455 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) GUU87_RS06470 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A GUU87_RS06475 ENOG4105CGZ zinc metallopeptidase GUU87_RS06485 ENOG4106KED esterase YpfH GUU87_RS06500 ENOG4105KUZ arsenate reductase GUU87_RS06510 ENOG4105BZS acriflavin resistance protein GUU87_RS06515 ENOG4105BZU Histidine kinase GUU87_RS06520 ENOG4105BZ8 glutamate synthase GUU87_RS06530 ENOG4108PVD exported protein GUU87_RS06535 ENOG4105CV1 Transketolase (EC 2.2.1.1) GUU87_RS06540 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GUU87_RS06545 ENOG4105C6K Malic enzyme GUU87_RS06550 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place GUU87_RS06555 ENOG4106S4J ethanolamine utilization protein EutP GUU87_RS06560 ENOG4105NDK ethanolamine utilization protein GUU87_RS06565 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase GUU87_RS06570 ENOG4107WUY phosphate acetyltransferase GUU87_RS06575 ENOG4105KNY Microcompartments protein GUU87_RS06580 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml GUU87_RS06585 ENOG4108EKI Dehydrogenase GUU87_RS06590 ENOG4107RWI ethanolamine utilization protein eutJ GUU87_RS06595 ENOG4105C0A alcohol dehydrogenase GUU87_RS06600 ENOG4105ENY Ethanolamine utilization protein eutH GUU87_RS06605 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase GUU87_RS06610 ENOG4105CPD ethanolamine ammonia-lyase GUU87_RS06620 ENOG4106D67 ethanolamine utilization protein GUU87_RS06625 ENOG4108X49 Ethanolamine utilization protein EutK GUU87_RS06630 ENOG4108K3Z AraC family transcriptional regulator GUU87_RS06640 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase GUU87_RS06645 ENOG4108R6G acetyltransferase GUU87_RS06650 ENOG4105QZU Inner membrane protein YfeZ GUU87_RS06655 ENOG4105E7K (LipO)protein GUU87_RS06660 ENOG4105EZR dyp-type peroxidase family protein GUU87_RS06665 ENOG4107S1E Beta-lactamase GUU87_RS06670 ENOG4105C5Y PTS System GUU87_RS06685 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr GUU87_RS06690 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein GUU87_RS06695 ENOG4108I5D sulfate abc transporter GUU87_RS06700 ENOG4105ECW sulfate abc transporter GUU87_RS06705 ENOG4108IJ6 ABC transporter GUU87_RS06710 ENOG4105C6T cysteine synthase GUU87_RS06715 ENOG4105M0Y GUU87_RS06725 ENOG4105C5Y PTS System GUU87_RS06730 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GUU87_RS06735 ENOG4105KZ7 phosphocarrier protein hpr GUU87_RS06740 ENOG4105C6T cysteine synthase GUU87_RS06760 ENOG4105VRT cytoplasmic protein GUU87_RS06765 ENOG4105DHU Bile acid GUU87_RS06770 ENOG4108M0I Transcriptional regulator GUU87_RS06775 ENOG4108NFH Sugar hydrolase GUU87_RS06780 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) GUU87_RS06785 ENOG4105EAA nucleoside GUU87_RS06790 ENOG4105F9F transposase GUU87_RS06800 ENOG4105CN8 Transcriptional regulator GUU87_RS06835 ENOG4105GXM Putative transcription regulator (DUF1323) GUU87_RS06840 ENOG4105HZG regulatoR GUU87_RS06855 ENOG4108KMM Diguanylate cyclase GUU87_RS06860 ENOG4105D9N nucleoside GUU87_RS06870 ENOG4109076 Conserved Protein GUU87_RS06875 ENOG4105VCT ion-transport protein YfeO GUU87_RS06885 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) GUU87_RS06890 ENOG410863U PTS System GUU87_RS06895 ENOG4105DC7 peptidase M24 GUU87_RS06900 ENOG4105CN9 Peptidase m42 family protein GUU87_RS06905 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GUU87_RS06910 ENOG4108CIP transcriptional regulator GUU87_RS06915 ENOG4105DY9 regulatoR GUU87_RS06920 ENOG4108HRK Histidine kinase GUU87_RS06925 ENOG4105CHM Aminotransferase GUU87_RS06935 ENOG4105D1S lipid A biosynthesis GUU87_RS06940 ENOG4105W9M Membrane GUU87_RS06950 ENOG4108V08 YfdX protein GUU87_RS06960 ENOG4105CFN oxalyl-CoA decarboxylase GUU87_RS06965 ENOG4108N2Y auxin Efflux GUU87_RS06970 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F GUU87_RS06975 ENOG4105BZU Histidine kinase GUU87_RS06980 ENOG4108WQH regulatoR GUU87_RS06985 ENOG4105CW7 secretion protein, HlyD family GUU87_RS06990 ENOG4105C0R drug resistance transporter emrb qaca subfamily GUU87_RS07005 ENOG4106NDP Transcriptional regulator GUU87_RS07010 ENOG4108HKT sucrose-6-phosphate hydrolase GUU87_RS07015 ENOG4105D7K pfkb domain protein GUU87_RS07020 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) GUU87_RS07035 ENOG4105S64 Formate nitrite transporter GUU87_RS07040 ENOG410903C (LipO)protein GUU87_RS07050 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation GUU87_RS07055 ENOG4105KZW UPF0381 protein GUU87_RS07070 ENOG4108BY2 phosphohistidine phosphatase GUU87_RS07080 ENOG4106PG1 outer membrane usher protein GUU87_RS07085 ENOG4108FZ9 Chaperone GUU87_RS07090 ENOG4105NEV Fimbrial GUU87_RS07095 ENOG4105UGQ Fimbrial GUU87_RS07100 ENOG4105US4 fimbrial-like protein yfcP GUU87_RS07130 ENOG4105EJ9 Membrane GUU87_RS07135 ENOG4108BPE -transporting atpase GUU87_RS07140 ENOG4105MH2 YfcL protein GUU87_RS07145 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) GUU87_RS07150 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GUU87_RS07155 ENOG4105F9N Major Facilitator Superfamily GUU87_RS07160 ENOG4106WZ1 flagella biosynthesis regulator GUU87_RS07170 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GUU87_RS07180 ENOG4105DQR SNARE associated Golgi GUU87_RS07190 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase GUU87_RS07195 ENOG4108S3P Sporulation domain protein GUU87_RS07200 ENOG4105E96 Colicin v production protein GUU87_RS07205 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase GUU87_RS07210 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase GUU87_RS07215 ENOG4105E89 ABC transporter GUU87_RS07220 ENOG4105E89 ABC transporter GUU87_RS07225 ENOG4105DSP amino acid AbC transporter GUU87_RS07230 ENOG4106YG3 ABC transporter GUU87_RS07235 ENOG4108JEH abc transporter atp-binding protein GUU87_RS07240 ENOG4105DNE Transposase GUU87_RS07245 ENOG4105ECP epimerase GUU87_RS07250 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase GUU87_RS07255 ENOG4105CYM Glutathione S-transferase GUU87_RS07260 ENOG4108SHQ Glutathione S-transferase GUU87_RS07265 ENOG4108RE9 Phosphodiesterase GUU87_RS07270 ENOG4105PTV Nudix Hydrolase GUU87_RS07275 ENOG4105CSX c4-dicarboxylate anaerobic carrier GUU87_RS07280 ENOG4105C6K Malic enzyme GUU87_RS07285 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) GUU87_RS07300 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 GUU87_RS07305 ENOG4107QWE )-transporter GUU87_RS07315 ENOG4105CHM Aminotransferase GUU87_RS07320 ENOG4107NQ8 LysR family Transcriptional regulator GUU87_RS07340 ENOG4105GKE subunit e GUU87_RS07345 ENOG4107QIZ NADH dehydrogenase GUU87_RS07350 ENOG4108IEH NADH dehydrogenase subunit g GUU87_RS07360 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GUU87_RS07365 ENOG4107UFS subunit j GUU87_RS07370 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GUU87_RS07375 ENOG4105D65 subunit l GUU87_RS07380 ENOG4105C8S subunit m GUU87_RS07390 ENOG4105GDX Domain of unknown function (DUF1877) GUU87_RS07410 ENOG4107YB6 acetyltransferase, (GNAT) family GUU87_RS07415 ENOG4105TNS Conserved Protein GUU87_RS07420 ENOG4105E4F Isochorismate synthase GUU87_RS07435 ENOG4108IPT Naphthoate synthase GUU87_RS07445 ENOG4105CEY Amp-dependent synthetase and ligase GUU87_RS07450 ENOG4106GZG polymyxin resistance protein B GUU87_RS07500 ENOG4108UII YfaZ family GUU87_RS07510 ENOG4105CNV Aldolase GUU87_RS07515 ENOG4105DNE Transposase GUU87_RS07520 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GUU87_RS07530 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A GUU87_RS07535 ENOG4105CXY transporter GUU87_RS07540 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase GUU87_RS07550 ENOG4105FQR PH-inducible protein involved in stress response GUU87_RS07555 ENOG4105XPH Ferredoxin GUU87_RS07560 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GUU87_RS07565 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GUU87_RS07570 ENOG4107GHC outer membrane autotransporter GUU87_RS07580 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GUU87_RS07585 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) GUU87_RS07590 ENOG4108QJJ Protein of unknown function (DUF1175) GUU87_RS07595 ENOG4107S52 alpha-2-macroglobulin domain protein GUU87_RS07600 ENOG41081SK signal peptide protein GUU87_RS07605 ENOG4105EDV vault protein GUU87_RS07610 ENOG4105BZU Histidine kinase GUU87_RS07615 ENOG41068CG regulatoR GUU87_RS07620 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC GUU87_RS07625 ENOG4105FCK Membrane GUU87_RS07630 ENOG4105CJ2 (LipO)protein GUU87_RS07635 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GUU87_RS07640 ENOG4105CF1 Alkylated DNA repair protein GUU87_RS07645 ENOG4105IBP Cyclic peptide transporter GUU87_RS07665 ENOG4108ZNS ferredoxin-type protein NapF GUU87_RS07670 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase GUU87_RS07680 ENOG4108BGM Quinol dehydrogenase periplasmic component GUU87_RS07685 ENOG4105GXZ Ferredoxin-type protein NapH GUU87_RS07690 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) GUU87_RS07695 ENOG4105CUW cytochrome C-TYPE protein GUU87_RS07700 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) GUU87_RS07705 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) GUU87_RS07710 ENOG41060IM Heme exporter protein GUU87_RS07715 ENOG4105X3C heme exporter protein GUU87_RS07725 ENOG4105DA4 cytochrome c-type biogenesis protein GUU87_RS07730 ENOG4107QX9 Thiol disulfide interChange protein GUU87_RS07735 ENOG4105KWW Biogenesis protein GUU87_RS07740 ENOG4105WH1 Two component transcriptional regulator luxr family GUU87_RS07755 ENOG4105E68 Sulfatase GUU87_RS07775 ENOG4105CFI type iii restriction protein res subunit GUU87_RS07780 ENOG4105I08 Pseudouridine synthase GUU87_RS07785 ENOG4105C2C drug resistance transporter, Bcr CflA GUU87_RS07790 ENOG4105HG6 GUU87_RS07795 ENOG4108JQ5 ABC transporter GUU87_RS07800 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component GUU87_RS07805 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component GUU87_RS07810 ENOG4105E43 Extracellular solute-binding protein, family 5 GUU87_RS07815 ENOG4105CXC rtn protein GUU87_RS07820 ENOG4107TT5 NLP P60 protein GUU87_RS07825 ENOG41076MN Phosphoesterase, PA-phosphatase related GUU87_RS07830 ENOG4105CKI cobalamin synthesis protein GUU87_RS07835 ENOG4105DEI Mannitol dehydrogenase GUU87_RS07845 ENOG4105KRS Proteinase inhibitor GUU87_RS07850 ENOG4105S8Q sugar efflux transporter GUU87_RS07855 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein GUU87_RS07860 ENOG4105DE4 1-phosphofructokinase GUU87_RS07865 ENOG4105DM4 PTS System GUU87_RS07870 ENOG4105DD7 kinase (PfkB family GUU87_RS07875 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) GUU87_RS07880 ENOG4105D9N nucleoside GUU87_RS07885 ENOG4108Y4K DNA-binding transcriptional activator GUU87_RS07895 ENOG4105D9N nucleoside GUU87_RS07900 ENOG4105DD7 kinase (PfkB family GUU87_RS07910 ENOG4105HMI Membrane GUU87_RS07915 ENOG4105DUM transcriptional regulator, lysR family GUU87_RS07920 ENOG4108IQI permease GUU87_RS07925 ENOG4105D05 Receptor GUU87_RS07930 ENOG4105C4W S-formylglutathione hydrolase GUU87_RS07940 ENOG4105DHF Membrane GUU87_RS07945 ENOG41060NJ transcriptional regulator GUU87_RS07950 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator GUU87_RS07955 ENOG4105C2J ABC transporter GUU87_RS07960 ENOG4108HWV )-transporter GUU87_RS07965 ENOG4107SJI Dehydrogenase GUU87_RS07970 ENOG4105BZ8 glutamate synthase GUU87_RS07975 ENOG4105Y9N Membrane GUU87_RS07980 ENOG4107GZ4 SanA protein GUU87_RS07990 ENOG41067MG lrgb family GUU87_RS08000 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) GUU87_RS08010 ENOG4105ETP RND efflux system, outer membrane lipoprotein GUU87_RS08015 ENOG4105H9W Short-chain dehydrogenase reductase Sdr GUU87_RS08020 ENOG4105KHU inner membrane protein YohD GUU87_RS08025 ENOG41069YE inner membrane protein yohC GUU87_RS08030 ENOG41061WM D-Alanyl-D-Alanine GUU87_RS08035 ENOG4105CXG d-lactate dehydrogenase GUU87_RS08040 ENOG4107QK4 glycoside hydrolase, family 3 domain protein GUU87_RS08045 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system GUU87_RS08050 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component GUU87_RS08055 ENOG4108IJ8 ABC transporter GUU87_RS08060 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component GUU87_RS08070 ENOG4108XDN Transcriptional regulator GUU87_RS08075 ENOG4108HRK Histidine kinase GUU87_RS08080 ENOG4108NEV two component transcriptional regulator, LytTR family GUU87_RS08085 ENOG4108W15 Protein of unknown function (DUF1456) GUU87_RS08090 ENOG4108YCW (LipO)protein GUU87_RS08095 ENOG410903U zinc ion binding GUU87_RS08100 ENOG4105DEG Vwa containing coxe family protein GUU87_RS08105 ENOG4105RD5 GUU87_RS08110 ENOG4105KKX ATPase associated with various cellular activities aaa_5 GUU87_RS08120 ENOG4108KDT Molybdate metabolism regulator GUU87_RS08125 ENOG4108KDT Molybdate metabolism regulator GUU87_RS08135 ENOG4105D1F ATP-binding protein GUU87_RS08140 ENOG41067AK Protein of unknown function (DUF2574) GUU87_RS08145 ENOG41063W2 Fimbrial protein GUU87_RS08150 ENOG4108MQF Chaperone GUU87_RS08155 ENOG4105CW0 outer membrane usher protein GUU87_RS08160 ENOG410662B Type-1 fimbrial protein GUU87_RS08165 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly GUU87_RS08185 ENOG4105DWF phosphomethylpyrimidine kinase GUU87_RS08190 ENOG4108UQ1 hydrolase, family 25 GUU87_RS08195 ENOG4105FDP GntR family transcriptional regulator GUU87_RS08200 ENOG4108TFM Kinase, PfkB family GUU87_RS08205 ENOG4108KD5 ADP-ribosylation crystallin J1 GUU87_RS08210 ENOG4105EAA nucleoside GUU87_RS08215 ENOG4105EIE fructose-bisphosphate aldolase GUU87_RS08230 ENOG41082GB PTS system galactitol-specific transporter subunit IIA GUU87_RS08235 ENOG41090UW PTS System GUU87_RS08240 ENOG4105DT3 PTS system, galactitol-specific IIc component GUU87_RS08245 ENOG4107WTH Galactitol-1-phosphate dehydrogenase GUU87_RS08260 ENOG41076Z6 Uncharacterized protein yegR GUU87_RS08265 ENOG4105CFP Peptidase U32 GUU87_RS08275 ENOG4105X54 addiction module antidote protein GUU87_RS08280 ENOG4105KWI UPF0339 protein GUU87_RS08285 ENOG4105E3W Two component transcriptional regulator (Winged helix family GUU87_RS08290 ENOG4105EB3 Histidine kinase GUU87_RS08330 ENOG4108M24 von Willebrand factor, type A GUU87_RS08335 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase GUU87_RS08340 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding GUU87_RS08345 ENOG4105R8A Heat shock protein GUU87_RS08350 ENOG4105D03 DNA-3-methyladenine glycosylase II GUU87_RS08355 ENOG4105BZU Histidine kinase GUU87_RS08360 ENOG4105DBI uridine monophosphokinase GUU87_RS08370 ENOG4108GAE asmA family GUU87_RS08375 ENOG4105EE5 Membrane protein terC GUU87_RS08380 ENOG4105DAY polysaccharide export protein GUU87_RS08385 ENOG4105KJF protein tyrosine phosphatase GUU87_RS08390 ENOG4105D75 Capsular exopolysaccharide family GUU87_RS08395 ENOG41090RK glycosyl transferase GUU87_RS08400 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB GUU87_RS08405 ENOG4107RXY Glycosyl transferase GUU87_RS08410 ENOG4108NYJ Colanic acid GUU87_RS08415 ENOG4105ECJ Glycosyl Transferase GUU87_RS08420 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF GUU87_RS08425 ENOG4105C0K Gdp-mannose 4,6-dehydratase GUU87_RS08430 ENOG4105C30 Nad-dependent epimerase dehydratase GUU87_RS08435 ENOG4105FGF GDP-mannose mannosyl hydrolase GUU87_RS08440 ENOG4106CD9 glycosyl transferase group 1 GUU87_RS08445 ENOG4105CJT Mannose-1-phosphate guanylyltransferase GUU87_RS08450 ENOG4107QKV phosphomannomutase GUU87_RS08455 ENOG4105D3Q Sugar transferase GUU87_RS08460 ENOG4105PSV Polysaccharide Biosynthesis Protein GUU87_RS08465 ENOG4105C74 pyruvyl transferase GUU87_RS08470 ENOG4107T8Q Glycosyl transferase (Group 1 GUU87_RS08475 ENOG4105G1A colanic acid biosynthesis protein GUU87_RS08480 ENOG4105DMT epimerase dehydratase GUU87_RS08485 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GUU87_RS08490 ENOG4105C1B dTDP-glucose 4-6-dehydratase GUU87_RS08495 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase GUU87_RS08500 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) GUU87_RS08505 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase GUU87_RS08520 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase GUU87_RS08525 ENOG4108RT7 Glycosyl transferase, family 2 GUU87_RS08545 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) GUU87_RS08565 ENOG4105F9F transposase GUU87_RS08575 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) GUU87_RS08580 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase GUU87_RS08595 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) GUU87_RS08600 ENOG4105ECC imidazole-glycerol-phosphate dehydratase GUU87_RS08610 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) GUU87_RS08625 ENOG4105VTW prevent-host-death family GUU87_RS08630 ENOG4105KRQ Addiction module toxin, Txe YoeB family GUU87_RS08635 ENOG4108535 NAD dependent epimerase/dehydratase family GUU87_RS08640 ENOG4105EQ1 Transcriptional regulator GUU87_RS08650 ENOG4105CUB amino acid GUU87_RS08655 ENOG4105CJB Exodeoxyribonuclease I GUU87_RS08660 ENOG4105DZ1 carboxypeptidase GUU87_RS08665 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) GUU87_RS08670 ENOG4105DR8 Membrane GUU87_RS08700 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles GUU87_RS08705 ENOG4106WJE Protein of unknown function (DUF987) GUU87_RS08710 ENOG4108YGG dna repair protein GUU87_RS08715 ENOG4105MFG Antirestriction protein GUU87_RS08720 ENOG4106H6R UPF0380 protein GUU87_RS08740 ENOG4108YIV GUU87_RS08745 ENOG4108F5E vimentin GUU87_RS08805 ENOG4108YZT Adenosylcobinamide kinase GUU87_RS08810 ENOG4108UHF Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) GUU87_RS08820 ENOG4108PXI ErfK YbiS YcfS YnhG GUU87_RS08830 ENOG4106P55 Transcriptional regulator GUU87_RS08835 ENOG4107R11 Transcriptional regulator GUU87_RS08845 ENOG4105UQX Mate efflux family protein GUU87_RS08855 ENOG4105CDY transcriptional regulatory protein GUU87_RS08860 ENOG4105FYV Amp nucleosidase GUU87_RS08865 ENOG4105CSH Transporter GUU87_RS08875 ENOG4105TNG K13735 adhesin invasin GUU87_RS08895 ENOG4108VKM cytochrome b561 GUU87_RS08900 ENOG4108MEK Metal-binding protein YodA GUU87_RS08915 ENOG4105VT2 5-hydroxyisourate hydrolase GUU87_RS08920 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GUU87_RS08925 ENOG4107ZY3 Histidine kinase GUU87_RS08935 ENOG4105FCK Membrane GUU87_RS08940 ENOG4105Y0K Inner membrane protein YedR GUU87_RS08945 ENOG4105EST Metal Dependent Phosphohydrolase GUU87_RS08950 ENOG4105DVF Cytosine-specific methyltransferase GUU87_RS08955 ENOG41090BB DNA mismatch endonuclease (vsr) GUU87_RS08960 ENOG4105FDR Membrane GUU87_RS08965 ENOG4105CKW Inner membrane protein yedI GUU87_RS08970 ENOG4105VNZ cytoplasmic protein GUU87_RS08985 ENOG4105YX3 cellular response to acidity GUU87_RS08995 ENOG4107TKS colanic acid capsular biosynthesis activation protein A GUU87_RS09000 ENOG4105D19 Role in flagellar biosynthesis (By similarity) GUU87_RS09005 ENOG4105VS8 Flagellar biosynthetic protein fliq GUU87_RS09010 ENOG4105CN7 Flagellar biosynthetic protein FliP GUU87_RS09015 ENOG4105K0P flagellar biosynthesis protein GUU87_RS09020 ENOG4105DD5 Flagellar motor switch protein GUU87_RS09025 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) GUU87_RS09030 ENOG4107ZI8 flagellar basal body-associated protein flil GUU87_RS09035 ENOG4105WF4 Flagellar hook-length control protein GUU87_RS09040 ENOG4105GSA Flagellar export protein flij GUU87_RS09045 ENOG4108JIR Flagellum-specific ATP synthase GUU87_RS09050 ENOG41090PJ Flagellar assembly protein GUU87_RS09055 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) GUU87_RS09060 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) GUU87_RS09070 ENOG410814C multidrug resistance protein GUU87_RS09075 ENOG4108V1U phospholipid-binding protein GUU87_RS09080 ENOG4108UQN AraC family transcriptional regulator GUU87_RS09085 ENOG4108RS6 transposase GUU87_RS09090 ENOG4105D7V transposase GUU87_RS09095 ENOG4108RAV Conserved protein GUU87_RS09100 ENOG4105KSU Redox protein GUU87_RS09105 ENOG41066VF YeeE YedE family protein GUU87_RS09110 ENOG4108W9D (LipO)protein GUU87_RS09115 ENOG4105E5K Alpha-amylase GUU87_RS09120 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) GUU87_RS09125 ENOG4105MQ3 flagellar protein FliS GUU87_RS09130 ENOG4105DTS flagellar hook-associated GUU87_RS09140 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GUU87_RS09145 ENOG4108M9K flagella biosynthesis protein FliZ GUU87_RS09150 ENOG4105EAB amino acid AbC transporter GUU87_RS09160 ENOG4105E5Q amino acid AbC transporter GUU87_RS09165 ENOG4105CDA abc transporter atp-binding protein GUU87_RS09170 ENOG4105VJY transcriptional regulator GUU87_RS09175 ENOG4105XVG cytoplasmic protein GUU87_RS09185 ENOG4105WH1 Two component transcriptional regulator luxr family GUU87_RS09195 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase GUU87_RS09215 ENOG4106RHG Yeca family GUU87_RS09220 ENOG4105E0U tyrosine-specific transport protein GUU87_RS09225 ENOG4105VVZ metal-binding protein GUU87_RS09230 ENOG41090A1 ferritin GUU87_RS09235 ENOG4105P23 (LipO)protein GUU87_RS09245 ENOG4105N4N Protein of unknown function (DUF2766) GUU87_RS09250 ENOG4108UEC Ferritin-like protein GUU87_RS09255 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator GUU87_RS09260 ENOG4105C2J ABC transporter GUU87_RS09265 ENOG4105CNN ABC, transporter GUU87_RS09270 ENOG4108K4C ec 3.1.3.12 GUU87_RS09280 ENOG4108VA4 Universal stress protein GUU87_RS09290 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region GUU87_RS09295 ENOG4107RD7 Flagellar Motor Protein, MotA GUU87_RS09300 ENOG4105ER2 Ompa motb domain protein GUU87_RS09305 ENOG4105CBS Chea signal transduction histidine kinase GUU87_RS09310 ENOG4108V3W Chemotaxis protein, CheW GUU87_RS09315 ENOG4105C8Q Methyl-accepting chemotaxis GUU87_RS09320 ENOG4105C8Q Methyl-accepting chemotaxis GUU87_RS09325 ENOG4105BZU Histidine kinase GUU87_RS09330 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) GUU87_RS09335 ENOG4108VYJ response regulator receiver protein GUU87_RS09340 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) GUU87_RS09345 ENOG4105D00 flagellar biosynthetic protein flhB GUU87_RS09350 ENOG4105D7B Flagellar biosynthesis protein flha GUU87_RS09355 ENOG4105W13 flagellar protein GUU87_RS09370 ENOG4106ZCM YecM protein GUU87_RS09380 ENOG4105CUW cytochrome C-TYPE protein GUU87_RS09385 ENOG4107QY8 reductase GUU87_RS09400 ENOG4105WJG Glutathione GUU87_RS09405 ENOG41081XQ Conserved Protein GUU87_RS09410 ENOG4105D3W isochorismatase GUU87_RS09420 ENOG4108TIT dATP pyrophosphohydrolase GUU87_RS09425 ENOG4105CDY transcriptional regulatory protein GUU87_RS09435 ENOG4107S01 Repressor protein MetJ GUU87_RS09455 ENOG4105FAV ABC, transporter GUU87_RS09460 ENOG4105FDK ABC transporter GUU87_RS09465 ENOG4105NXV High-affinity zinc uptake system protein GUU87_RS09470 ENOG4105DR5 peptidase GUU87_RS09475 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase GUU87_RS09480 ENOG4105CA9 Pyruvate kinase GUU87_RS09485 ENOG4106KNT transcriptional regulator GUU87_RS09490 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase GUU87_RS09495 ENOG4105C01 Dihydroxy-acid dehydratase GUU87_RS09500 ENOG4108UHU Aldolase GUU87_RS09510 ENOG4105X2V dna damage-inducible protein GUU87_RS09515 ENOG4105RSZ secreted protein GUU87_RS09520 ENOG4108Q2J Inner membrane protein YebE GUU87_RS09525 ENOG4105CUG Oligopeptidase b GUU87_RS09530 ENOG4105UMD exodeoxyribonuclease X GUU87_RS09535 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GUU87_RS09540 ENOG4105MPK DNA polymerase III subunit theta GUU87_RS09545 ENOG4105FXM Copper resistance protein GUU87_RS09550 ENOG4108PNC copper resistance GUU87_RS09555 ENOG4105NKT exported protein GUU87_RS09560 ENOG4108R1E Serine threonine protein phosphatase 1 GUU87_RS09565 ENOG4105UVW uncharacterized protein yebW GUU87_RS09570 ENOG4105WT8 Protein of unknown function (DUF1480) GUU87_RS09580 ENOG4105DY2 Paraquat-inducible protein b GUU87_RS09585 ENOG4105H2K paraquat-inducible protein a GUU87_RS09590 ENOG4108ZGC gaf domain protein GUU87_RS09600 ENOG4105CN1 protease GUU87_RS09610 ENOG4105C0R drug resistance transporter emrb qaca subfamily GUU87_RS09615 ENOG4105J4Q Transcriptional regulator GUU87_RS09620 ENOG4105TIK GUU87_RS09630 ENOG4105Q3Y exported protein GUU87_RS09635 ENOG410610J Protein of unknown function (DUF2627) GUU87_RS09640 ENOG4105VEQ Cold shock protein GUU87_RS09645 ENOG4105DHI Methyltransferase GUU87_RS09660 ENOG4105F3R pts system mannose fructose sorbose family iid GUU87_RS09665 ENOG4105ETZ PTS System GUU87_RS09670 ENOG4108EQA pts system GUU87_RS09675 ENOG4105EE5 Membrane protein terC GUU87_RS09680 ENOG4107XTP (EAL) domain protein GUU87_RS09685 ENOG4105EJQ L-serine dehydratase GUU87_RS09695 ENOG4105CRQ synthase (Component I) GUU87_RS09705 ENOG4105V2F Uncharacterized protein yoac GUU87_RS09710 ENOG4105M4H endoribonuclease L-psp GUU87_RS09715 ENOG4105DVT helicase GUU87_RS09720 ENOG41072GX Peptidase M22 Glycoprotease GUU87_RS09725 ENOG4105Y4Z Outer Membrane Lipoprotein GUU87_RS09730 ENOG4105CEY Amp-dependent synthetase and ligase GUU87_RS09735 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) GUU87_RS09740 ENOG4105E3J oxidoreductase GUU87_RS09745 ENOG4105DVW rieske (2Fe-2S) GUU87_RS09750 ENOG4105C94 Transporter GUU87_RS09755 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) GUU87_RS09760 ENOG4105EJC lysr family transcriptional regulator GUU87_RS09780 ENOG4105Y3U Transglycosylase-associated protein GUU87_RS09790 ENOG4106G4W GUU87_RS09795 ENOG410620I Diguanylate cyclase GUU87_RS09800 ENOG4105UCG Domain of unknown function (DUF333) GUU87_RS09805 ENOG4105K78 MarR family Transcriptional regulator GUU87_RS09810 ENOG4105DJ2 Major Facilitator Superfamily GUU87_RS09815 ENOG4105R1U AraC Family Transcriptional Regulator GUU87_RS09830 ENOG4108KXH Ybak prolyl-tRNA synthetase associated GUU87_RS09835 ENOG4108KHP Diguanylate cyclase GUU87_RS09840 ENOG4106KTS Inner membrane protein yeaI GUU87_RS09850 ENOG4105CYN Serine protein kinase GUU87_RS09855 ENOG4105GNX MltA-interacting MipA family protein GUU87_RS09860 ENOG4105CV8 reductase GUU87_RS09865 ENOG4105DSB aldose 1-epimerase GUU87_RS09870 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GUU87_RS09880 ENOG4105VUT cytoplasmic protein GUU87_RS09885 ENOG4108RWI nicotinamidase GUU87_RS09890 ENOG4105HDK L-asparaginase GUU87_RS09895 ENOG4105D07 Signal peptide peptidase, SppA GUU87_RS09900 ENOG41069NU Nitroreductase GUU87_RS09910 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GUU87_RS09920 ENOG4105D82 Glutamate dehydrogenase GUU87_RS09925 ENOG4105MTM Protein of unknown function (DUF1496) GUU87_RS09930 ENOG4105M6F mutator MutT protein GUU87_RS09935 ENOG4108T9J Cdp-alcohol phosphatidyltransferase GUU87_RS09940 ENOG4107RM6 sulfurtransferase GUU87_RS09945 ENOG4108VGW abc transporter atp-binding protein GUU87_RS09950 ENOG4105CXZ ABC transporter, permease GUU87_RS09955 ENOG4105VNH ABC transporter solute-binding protein GUU87_RS09960 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) GUU87_RS09965 ENOG4108N5C SNARE associated Golgi protein-related protein GUU87_RS09970 ENOG4108KCW iron-sulfur cluster binding GUU87_RS09975 ENOG4108RSN SNARE associated Golgi GUU87_RS09980 ENOG4105CGK Exodeoxyribonuclease III GUU87_RS10010 ENOG4108SPG Periplasmic Protein GUU87_RS10020 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) GUU87_RS10030 ENOG4105KKI DNA-binding transcriptional activator OsmE GUU87_RS10035 ENOG4105VZJ PTS System GUU87_RS10040 ENOG4105CK1 PTS System GUU87_RS10045 ENOG4105VCP PTS System GUU87_RS10050 ENOG4105EZV Transcriptional regulator GUU87_RS10055 ENOG4105F8D glycoside hydrolase family 4 GUU87_RS10065 ENOG4105CH6 catalase GUU87_RS10085 ENOG4108ETY sodium dicarboxylate symporter GUU87_RS10090 ENOG4107K5X Membrane-bound metal-dependent hydrolase GUU87_RS10095 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 GUU87_RS10100 ENOG4107PN8 YfeABCD locus regulator GUU87_RS10105 ENOG4105FGM Fructosamine kinase GUU87_RS10110 ENOG4105P10 Uncharacterized protein ydiZ GUU87_RS10115 ENOG4105DE4 1-phosphofructokinase GUU87_RS10120 ENOG4108NE3 Salt-induced outer membrane protein GUU87_RS10145 ENOG41082NX 50s ribosomal protein l35 GUU87_RS10150 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) GUU87_RS10180 ENOG4108V06 Glutathione peroxidase GUU87_RS10190 ENOG4108QBX (LipO)protein GUU87_RS10195 ENOG4108TC0 Diguanylate phosphodiesterase GUU87_RS10205 ENOG4106EDX Hemin uptake protein GUU87_RS10210 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GUU87_RS10220 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) GUU87_RS10225 ENOG4105CEY Amp-dependent synthetase and ligase GUU87_RS10230 ENOG41090P5 ferredoxin-like protein GUU87_RS10235 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GUU87_RS10240 ENOG4105C10 Electron transfer flavoprotein GUU87_RS10245 ENOG4105CV7 Electron transfer flavoprotein GUU87_RS10250 ENOG4105W4W Transcriptional regulator GUU87_RS10255 ENOG4105C1G acyl-Coa dehydrogenase GUU87_RS10260 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) GUU87_RS10280 ENOG4105EMV Major Facilitator GUU87_RS10285 ENOG4105SUA Ydil protein GUU87_RS10295 ENOG4105IPI Membrane GUU87_RS10300 ENOG4105CQB FAD linked oxidase domain protein GUU87_RS10305 ENOG4105KA0 thioesterase Superfamily protein GUU87_RS10310 ENOG410671Z uncharacterized protein ydiH GUU87_RS10315 ENOG4108Z4V iron-sulfur cluster assembly GUU87_RS10320 ENOG4105DIW FeS assembly protein SUFB GUU87_RS10325 ENOG4105C3K feS assembly ATPase SufC GUU87_RS10330 ENOG4105JRK feS assembly protein SufD GUU87_RS10345 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GUU87_RS10350 ENOG4105KMX major outer membrane lipoprotein GUU87_RS10355 ENOG4105CA9 Pyruvate kinase GUU87_RS10360 ENOG4105RFR Protein of unknown function (DUF2767) GUU87_RS10365 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein GUU87_RS10370 ENOG4105WE2 aldehyde ferredoxin oxidoreductase GUU87_RS10375 ENOG4105JVW GUU87_RS10380 ENOG4108393 oxidoreductase Fe-S subunit GUU87_RS10385 ENOG4108NWD Cytochrome GUU87_RS10390 ENOG4108Y7C Conserved Protein GUU87_RS10395 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain GUU87_RS10400 ENOG4105N0V mono-oxygenase ydhR GUU87_RS10425 ENOG4108R6K riboflavin synthase, subunit alpha GUU87_RS10430 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase GUU87_RS10435 ENOG4105CZQ inner membrane transport protein YdhC GUU87_RS10440 ENOG4105F52 Transcriptional regulator GUU87_RS10455 ENOG4105F27 Major Facilitator GUU87_RS10460 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GUU87_RS10465 ENOG4105K4H Nlp p60 protein GUU87_RS10470 ENOG4105M2J Glutaredoxin GUU87_RS10475 ENOG4107QRT dEAD DEAH box helicase GUU87_RS10485 ENOG4108UYE Lactoylglutathione lyase GUU87_RS10490 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GUU87_RS10495 ENOG4108WUH Transcriptional regulator, TetR family GUU87_RS10500 ENOG4105XZD Fe-S protein GUU87_RS10505 ENOG4107RGM aldo keto reductase GUU87_RS10510 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GUU87_RS10515 ENOG4105DSW Fusaric acid resistance protein GUU87_RS10520 ENOG4105Y49 secretion protein, HlyD family GUU87_RS10535 ENOG4108XTF Outer Membrane Lipoprotein GUU87_RS10545 ENOG410642K Lysozyme inhibitor GUU87_RS10560 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) GUU87_RS10565 ENOG4108K3A Glutathione S-transferase GUU87_RS10570 ENOG4105DUX Transporter GUU87_RS10575 ENOG4105CSM endonuclease III GUU87_RS10585 ENOG4108UQQ Electron transport complex GUU87_RS10610 ENOG4105M9B inner membrane protein ydgK GUU87_RS10615 ENOG4105QZ5 OriC-binding nucleoid-associated protein GUU87_RS10620 ENOG4106C6R beta-lactam resistance protein GUU87_RS10625 ENOG4105D9R oxidoreductase GUU87_RS10635 ENOG4105C87 Aminotransferase class I and II GUU87_RS10640 ENOG4105CI1 PTS System GUU87_RS10645 ENOG4107P2S Transcriptional regulator GUU87_RS10650 ENOG4107ZQV short-chain dehydrogenase reductase GUU87_RS10655 ENOG4105XEA Tetr family transcriptional regulator GUU87_RS10660 ENOG4105CNT hydrolase family 2 GUU87_RS10665 ENOG4105CT4 transporter GUU87_RS10670 ENOG4108QNI outer membrane porin protein GUU87_RS10675 ENOG4106J39 exported protein GUU87_RS10680 ENOG4105EIP mannose-6-phosphate isomerase GUU87_RS10685 ENOG4107GFK fumarate GUU87_RS10690 ENOG4105C9Q fumarate hydratase class II GUU87_RS10700 ENOG4105JJR Histidine kinase GUU87_RS10705 ENOG4107EXC regulatoR GUU87_RS10710 ENOG4105RA2 Membrane GUU87_RS10715 ENOG410642E Short chain dehydrogenase GUU87_RS10720 ENOG4105D5Q Arginine ornithine antiporter GUU87_RS10725 ENOG4105C5D exported protein GUU87_RS10730 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GUU87_RS10735 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GUU87_RS10740 ENOG4105DSF transport protein GUU87_RS10760 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap GUU87_RS10775 ENOG4105D94 Major Facilitator Superfamily GUU87_RS10780 ENOG4106NZI LysR family Transcriptional regulator GUU87_RS10785 ENOG4105DAG ROK family GUU87_RS10790 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) GUU87_RS10800 ENOG4108NEM leader-binding protein dmsD GUU87_RS10805 ENOG4107KGK dmso reductase anchor subunit GUU87_RS10810 ENOG4105QAX Iron-sulfur GUU87_RS10815 ENOG4105C3J Cysteine desulfurase GUU87_RS10820 ENOG4107QY8 reductase GUU87_RS10825 ENOG4105KBG Protein of unknown function (DUF1161) GUU87_RS10835 ENOG4108MK9 spermidine N(1)-acetyltransferase GUU87_RS10850 ENOG4105CXK mandelate racemase muconate lactonizing GUU87_RS10855 ENOG4105CPQ Dehydrogenase GUU87_RS10865 ENOG4105DEI Mannitol dehydrogenase GUU87_RS10870 ENOG41061EV selenium-binding protein YdfZ GUU87_RS10875 ENOG4107XBN GntR Family Transcriptional Regulator GUU87_RS10880 ENOG4105EMU Dehydrogenase GUU87_RS10885 ENOG4105DGW oligopeptidase A GUU87_RS10890 ENOG4108WTK competence damage-inducible protein GUU87_RS10895 ENOG4108YDI single-species biofilm formation on inanimate substrate GUU87_RS10900 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria GUU87_RS10910 ENOG4105E5W Transporter GUU87_RS10915 ENOG4108594 Permease of the drug metabolite transporter GUU87_RS10920 ENOG4105FDP GntR family transcriptional regulator GUU87_RS10930 ENOG4105CK1 PTS System GUU87_RS10935 ENOG4105VCP PTS System GUU87_RS10945 ENOG4105CS2 ec 3.2.1.21 GUU87_RS10950 ENOG4106DNR multiple antibiotic resistance protein GUU87_RS10955 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF GUU87_RS10960 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes GUU87_RS10980 ENOG4105EGI Transcriptional regulator GUU87_RS10985 ENOG4105C26 Dehydrogenase GUU87_RS10990 ENOG4105CSV Glutaminase GUU87_RS10995 ENOG4105M0C cytoplasmic protein GUU87_RS11000 ENOG4105BZU Histidine kinase GUU87_RS11010 ENOG4105FFC UPF0187 protein GUU87_RS11020 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound GUU87_RS11035 ENOG4105F5R ABC transporter GUU87_RS11045 ENOG4105C2J ABC transporter GUU87_RS11065 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein GUU87_RS11070 ENOG4105CAF HipA N-terminal domain protein GUU87_RS11095 ENOG4108RQP Major type 1 subunit fimbrin GUU87_RS11105 ENOG4105CW0 outer membrane usher protein GUU87_RS11110 ENOG4108WDE Fimbrial protein GUU87_RS11115 ENOG4106318 fimbrial-like protein YdeR GUU87_RS11120 ENOG4106PIH fimbrial-like protein ydeQ GUU87_RS11125 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit GUU87_RS11140 ENOG4105ENH Sulfatase GUU87_RS11145 ENOG4105C4X radical SAM domain protein GUU87_RS11155 ENOG4105CQ0 ABC transporter GUU87_RS11160 ENOG4105PE1 Receptor GUU87_RS11165 ENOG4107RAN Peptidase, M16 GUU87_RS11170 ENOG4105CVK Glutamate decarboxylase GUU87_RS11175 ENOG4105E5D amino acid GUU87_RS11180 ENOG4105F32 YngK protein GUU87_RS11190 ENOG4105BZU Histidine kinase GUU87_RS11195 ENOG4108UQS dipeptidase GUU87_RS11200 ENOG4105DEF Extracellular solute-binding protein, family 5 GUU87_RS11205 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GUU87_RS11210 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GUU87_RS11215 ENOG4105C3U ABC transporter GUU87_RS11220 ENOG4107H6U ABC transporter GUU87_RS11225 ENOG4108Z9K Osmotically inducible protein GUU87_RS11230 ENOG4105TPS biofilm-dependent modulation protein GUU87_RS11235 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein GUU87_RS11245 ENOG4105DQ4 alcohol dehydrogenase GUU87_RS11250 ENOG41084S7 Plasmid maintenance system antidote protein GUU87_RS11255 ENOG4108MG3 formate dehydrogenase GUU87_RS11260 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GUU87_RS11270 ENOG4105RPH Inner membrane protein YddG GUU87_RS11280 ENOG4108UI3 Leucine Rich repeat GUU87_RS11285 ENOG4107QND Nitrite extrusion protein GUU87_RS11290 ENOG4105CRU nitrate reductase, alpha subunit GUU87_RS11295 ENOG4108IUE nitrate reductase beta subunit GUU87_RS11300 ENOG4108NZN Respiratory nitrate reductase 2 delta chain GUU87_RS11305 ENOG4105D0D Nitrate reductase 2, gamma subunit GUU87_RS11310 ENOG4105JAB phenazine biosynthesis protein, phzf family GUU87_RS11315 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase GUU87_RS11320 ENOG4108MEJ flavin reductase domain protein GUU87_RS11340 ENOG4105CNA YD repeat protein GUU87_RS11375 ENOG4105CNA YD repeat protein GUU87_RS11390 ENOG4108N27 Glutathione S-transferase GUU87_RS11395 ENOG4105C85 amino acid GUU87_RS11400 ENOG4108NS2 receptor GUU87_RS11405 ENOG4105CHB tonB-dependent Receptor GUU87_RS11410 ENOG4108WYP Transcriptional regulator GUU87_RS11415 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein GUU87_RS11420 ENOG4108Z7F N-acetyltransferase GUU87_RS11425 ENOG4108T9Y Inner membrane protein ydcZ GUU87_RS11430 ENOG4105R71 cytoplasmic protein GUU87_RS11435 ENOG410654E Membrane GUU87_RS11450 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component GUU87_RS11455 ENOG4105D81 ABC transporter, permease GUU87_RS11460 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GUU87_RS11465 ENOG4107TYH extracellular solute-binding protein family 1 GUU87_RS11470 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GUU87_RS11475 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin GUU87_RS11485 ENOG4105RR0 Protein of unknown function (DUF2554) GUU87_RS11490 ENOG4105CFP Peptidase U32 GUU87_RS11495 ENOG4108JCI Transcriptional regulator GUU87_RS11500 ENOG4105DKK Benzoate GUU87_RS11505 ENOG4105D7V transposase GUU87_RS11515 ENOG4108KKZ (LipO)protein GUU87_RS11520 ENOG41088CC tellurite resistance protein tehB GUU87_RS11525 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein GUU87_RS11530 ENOG4107WE3 acetyltransferase YdcK GUU87_RS11535 ENOG4108Z9I -acetyltransferase GUU87_RS11540 ENOG4105Z2P Protein of unknown function (DUF465) GUU87_RS11550 ENOG4105E32 cytoplasmic protein GUU87_RS11555 ENOG4105DDW LysR family Transcriptional regulator GUU87_RS11560 ENOG4105C8Q Methyl-accepting chemotaxis GUU87_RS11565 ENOG4107NK6 Hok/gef family GUU87_RS11570 ENOG4105UPP uncharacterized protein ydcA GUU87_RS11575 ENOG4105CPW cytochrome b561 GUU87_RS11580 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GUU87_RS11585 ENOG4105C26 Dehydrogenase GUU87_RS11590 ENOG4107DB1 DUF218 domain GUU87_RS11595 ENOG4105CQ7 ATP-dependent helicase GUU87_RS11605 ENOG41077RS Phosphatase GUU87_RS11615 ENOG4108HPI phosphatidate Cytidylyltransferase GUU87_RS11620 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase GUU87_RS11630 ENOG4107S5I aldo keto reductase GUU87_RS11635 ENOG4108Z0R Transferase GUU87_RS11640 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein GUU87_RS11645 ENOG4105DZS Phenylacetate-CoA ligase GUU87_RS11650 ENOG4105CHU acetyl-coa acetyltransferase GUU87_RS11655 ENOG4108ZJI phenylacetic acid degradation protein GUU87_RS11660 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase GUU87_RS11665 ENOG4108UKI Enoyl-CoA hydratase GUU87_RS11670 ENOG4105E39 Enoyl-CoA hydratase GUU87_RS11675 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GUU87_RS11680 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit GUU87_RS11685 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit GUU87_RS11690 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit GUU87_RS11695 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit GUU87_RS11700 ENOG4105DXM phenylacetic acid degradation protein GUU87_RS11705 ENOG4105F11 amine oxidase GUU87_RS11710 ENOG4105C26 Dehydrogenase GUU87_RS11715 ENOG4108WFR AraC Family Transcriptional Regulator GUU87_RS11720 ENOG4105WXT Conserved Protein GUU87_RS11725 ENOG410689M (LipO)protein GUU87_RS11730 ENOG4107H52 Dicarboxylate transport GUU87_RS11735 ENOG4105C5I Dehydrogenase GUU87_RS11740 ENOG41090X5 Heat shock protein hslJ GUU87_RS11750 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) GUU87_RS11755 ENOG4105FCK Membrane GUU87_RS11760 ENOG4108RW8 Universal stress protein F GUU87_RS11775 ENOG4105W3V DNA-binding, transcriptional regulator GUU87_RS11780 ENOG4105MN3 Resolvase GUU87_RS11785 ENOG4105UZW Tail fiber assembly protein GUU87_RS11790 ENOG4108X9F tail fiber protein GUU87_RS11900 ENOG4108ES9 ParB domain protein nuclease GUU87_RS11905 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) GUU87_RS11915 ENOG4105KUS lysozyme GUU87_RS11920 ENOG4105QFS Lysis protein S homolog from lambdoid prophage GUU87_RS11930 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA GUU87_RS11940 ENOG4105RWQ Protein of unknown function (DUF1364) GUU87_RS11955 ENOG4105F27 Major Facilitator GUU87_RS11960 ENOG4108NH8 Cation transport protein GUU87_RS11970 ENOG4105EXU Membrane GUU87_RS11975 ENOG4105C94 Transporter GUU87_RS12020 ENOG4107C82 Rac prophage GUU87_RS12030 ENOG41076J9 exonuclease VIII GUU87_RS12035 ENOG4108PNI recT protein GUU87_RS12040 ENOG4106YAH restriction alleviation and modification enhancement GUU87_RS12045 ENOG41070YT Rac prophage GUU87_RS12050 ENOG4107160 Rac prophage GUU87_RS12055 ENOG4107R08 Integrase GUU87_RS12060 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) GUU87_RS12065 ENOG4105C1J atp-dependent rna helicase GUU87_RS12075 ENOG4105BZU Histidine kinase GUU87_RS12080 ENOG4108DG9 Smr protein MutS2 GUU87_RS12085 ENOG4106KR7 LysR family Transcriptional regulator GUU87_RS12090 ENOG4105CH2 amidohydrolase GUU87_RS12095 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B GUU87_RS12100 ENOG4105CFC Transporter GUU87_RS12105 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GUU87_RS12110 ENOG4105DS0 Transcriptional regulator, Crp Fnr family GUU87_RS12115 ENOG4105Q9Y Universal stress protein GUU87_RS12120 ENOG4105S5I Membrane GUU87_RS12125 ENOG4105D64 Mechanosensitive ion channel GUU87_RS12130 ENOG4107QSI ABC, transporter GUU87_RS12135 ENOG4105EQ2 LysR family Transcriptional regulator GUU87_RS12140 ENOG4105ENX hydrolase GUU87_RS12155 ENOG4105KXI murein peptide amidase A GUU87_RS12160 ENOG4107S8C mandelate racemase muconate lactonizing GUU87_RS12165 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) GUU87_RS12170 ENOG4108JU8 Transcriptional regulator GUU87_RS12180 ENOG4105CM6 amino acid regulated cytosolic protein GUU87_RS12185 ENOG4105FKQ transcriptional regulator GUU87_RS12190 ENOG4107EFV Outer membrane protein G GUU87_RS12195 ENOG4108IJ9 (ABC) transporter GUU87_RS12200 ENOG4107URF beta-phospho-glucomutase GUU87_RS12205 ENOG4105C71 hydrolase family 65, central catalytic GUU87_RS12210 ENOG4105CK5 oxidoreductase GUU87_RS12215 ENOG4107TYA transient receptor potential locus GUU87_RS12220 ENOG4107RRD Dehydrogenase GUU87_RS12225 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component GUU87_RS12230 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component GUU87_RS12235 ENOG4105WEM extracellular solute-binding protein GUU87_RS12240 ENOG4107QW3 Sucrose phosphorylase GUU87_RS12245 ENOG4105K8Z Phage shock protein GUU87_RS12250 ENOG4105NNG Peripheral inner membrane phage-shock protein GUU87_RS12255 ENOG4105FM1 phage shock protein C GUU87_RS12260 ENOG4105YYT phage shock protein B GUU87_RS12265 ENOG41087YS Phage shock protein A GUU87_RS12270 ENOG4105E51 psp operon transcriptional activator GUU87_RS12275 ENOG4108JPW Aminotransferase GUU87_RS12280 ENOG4105CJP fad dependent oxidoreductase GUU87_RS12285 ENOG4105C26 Dehydrogenase GUU87_RS12290 ENOG4107VRI Transcriptional regulator GUU87_RS12295 ENOG4108Z86 Glutamine amidotransferase GUU87_RS12300 ENOG4105CFQ glutamine synthetase GUU87_RS12310 ENOG4105CUB amino acid GUU87_RS12315 ENOG4105N0E Protein of unknown function (DUF2543) GUU87_RS12320 ENOG4108HIY periplasmic GUU87_RS12325 ENOG4108I5W peptide transport system, permease protein GUU87_RS12330 ENOG4108EU3 peptide transport system, permease GUU87_RS12335 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein GUU87_RS12340 ENOG4108JQ2 peptide transport system atp-binding protein GUU87_RS12345 ENOG4105WDY DNA (cytosine-5-)-methyltransferase GUU87_RS12350 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH GUU87_RS12370 ENOG4105BZU Histidine kinase GUU87_RS12380 ENOG4105N2W Transcriptional regulator GUU87_RS12385 ENOG41061RM osmotically inducible lipoprotein GUU87_RS12390 ENOG4108ZJT translation initiation factor, Sui1 GUU87_RS12400 ENOG4105CFV Tetratricopeptide repeat protein GUU87_RS12405 ENOG4105Q4A inner membrane protein yciS GUU87_RS12410 ENOG4105EYK Phosphatidylglycerophosphatase B GUU87_RS12420 ENOG4107QM5 aconitate hydratase GUU87_RS12440 ENOG4107R11 Transcriptional regulator GUU87_RS12445 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GUU87_RS12450 ENOG4105RKX Protein of unknown function (DUF2498) GUU87_RS12455 ENOG4105ERU peptidase GUU87_RS12460 ENOG4105UBK short-chain dehydrogenase reductase GUU87_RS12465 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase GUU87_RS12470 ENOG4105FE9 pseudouridine synthase GUU87_RS12475 ENOG4107RTD sua5 ycio yrdc ywlc family protein GUU87_RS12480 ENOG4105DB7 PHP domain protein GUU87_RS12490 ENOG4105CRQ synthase (Component I) GUU87_RS12495 ENOG4108EFP Anthranilate synthase component II GUU87_RS12500 ENOG4105DK0 Indole-3-glycerol phosphate synthase GUU87_RS12520 ENOG4108Z9Z response to DNA damage stimulus GUU87_RS12525 ENOG4108N8X transition metal ion binding GUU87_RS12530 ENOG4105EIF outer membrane protein W GUU87_RS12550 ENOG4105NAU thioesterase Superfamily protein GUU87_RS12555 ENOG410822N TonB family GUU87_RS12560 ENOG4105K9H YciI-like protein GUU87_RS12565 ENOG4107SVH Potassium channel protein GUU87_RS12585 ENOG4108JQ7 (ABC) transporter GUU87_RS12590 ENOG4105C3U ABC transporter GUU87_RS12595 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GUU87_RS12605 ENOG4108J59 Extracellular solute-binding protein, family 5 GUU87_RS12615 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein GUU87_RS12620 ENOG4108EKI Dehydrogenase GUU87_RS12625 ENOG4107104 thymidine kinase GUU87_RS12630 ENOG4108SAU DNA-binding protein H-ns GUU87_RS12635 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GUU87_RS12640 ENOG4105I93 response regulator GUU87_RS12645 ENOG4105D78 K07001 NTE family protein GUU87_RS12655 ENOG4105CIY formyltetrahydrofolate deformylase GUU87_RS12675 ENOG41076YT nitrate reductase, gamma subunit GUU87_RS12680 ENOG4105R3A Nitrate reductase GUU87_RS12685 ENOG4108IUE nitrate reductase beta subunit GUU87_RS12690 ENOG4105CRU nitrate reductase, alpha subunit GUU87_RS12695 ENOG4105DQQ Major facilitator superfamily MFS_1 GUU87_RS12700 ENOG4105BZU Histidine kinase GUU87_RS12705 ENOG4105WH1 Two component transcriptional regulator luxr family GUU87_RS12710 ENOG4105ID0 Putative invasin GUU87_RS12715 ENOG41090EX DsrE family GUU87_RS12720 ENOG4108NH8 Cation transport protein GUU87_RS12725 ENOG4105WS7 Cation transport regulator GUU87_RS12730 ENOG4105EWV Sodium calcium exchanger membrane region GUU87_RS12755 ENOG41063JG Transcriptional regulator GUU87_RS12760 ENOG4108YY7 Invasion gene expression up-regulator SirB GUU87_RS12765 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) GUU87_RS12790 ENOG4105C5T Phosphoribosyl pyrophosphate synthase GUU87_RS12795 ENOG4105CHH sulfate transporter GUU87_RS12800 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria GUU87_RS12810 ENOG4105C3G gtp-binding protein GUU87_RS12815 ENOG4105I1J Autotransporter GUU87_RS12820 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family GUU87_RS12825 ENOG4105CMT Dihydroxyacetone kinase GUU87_RS12830 ENOG4108UTZ Dihydroxyacetone kinase GUU87_RS12835 ENOG4105VDH Dihydroxyacetone kinase GUU87_RS12855 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) GUU87_RS12865 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A GUU87_RS12875 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GUU87_RS12885 ENOG4105ED1 spovr family GUU87_RS12900 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) GUU87_RS12905 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) GUU87_RS12910 ENOG4105KT5 UmuD protein GUU87_RS12925 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase GUU87_RS12935 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium GUU87_RS12940 ENOG4105S66 prophage protein GUU87_RS12950 ENOG4107QMS site-determining protein GUU87_RS12985 ENOG410658X GUU87_RS13005 ENOG4105BZU Histidine kinase GUU87_RS13010 ENOG410738I uncharacterized protein ymgC GUU87_RS13020 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB GUU87_RS13025 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component GUU87_RS13030 ENOG4105BZU Histidine kinase GUU87_RS13035 ENOG4108XDN Transcriptional regulator GUU87_RS13040 ENOG41064WM Uncharacterized protein YcgX GUU87_RS13055 ENOG4108HMX isocitrate dehydrogenase (NADP) GUU87_RS13060 ENOG4108R99 pseudouridine synthase GUU87_RS13080 ENOG4107QTF adenylosuccinate lyase GUU87_RS13085 ENOG4105XJC Two component transcriptional regulator (Winged helix family GUU87_RS13090 ENOG4105IFJ Histidine kinase GUU87_RS13095 ENOG4105EZE Cupin 4 family protein GUU87_RS13105 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GUU87_RS13110 ENOG4105F38 ABC transporter, permease GUU87_RS13115 ENOG4105D38 putrescine abc transporter GUU87_RS13120 ENOG4107RUE extracellular solute-binding protein family 1 GUU87_RS13140 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) GUU87_RS13150 ENOG4105D60 lipoprotein releasing system transmembrane protein GUU87_RS13155 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) GUU87_RS13160 ENOG4105D60 lipoprotein releasing system transmembrane protein GUU87_RS13165 ENOG4105IQC Inner membrane protein YcfT GUU87_RS13170 ENOG4108JA2 transcriptioN-repair coupling factor GUU87_RS13175 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GUU87_RS13180 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction GUU87_RS13185 ENOG4108IND Tetr family transcriptional regulator GUU87_RS13190 ENOG4107MBR 17 kDa surface antigen GUU87_RS13195 ENOG4105CEP NADH dehydrogenase GUU87_RS13215 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) GUU87_RS13220 ENOG41090DQ Lipoprotein GUU87_RS13225 ENOG4105K59 histidine triad (HIT) protein GUU87_RS13230 ENOG4105CNM Receptor GUU87_RS13235 ENOG4105CI1 PTS System GUU87_RS13240 ENOG4105F8V Hydrolase, tatD family GUU87_RS13245 ENOG4107QRG dna polymerase iii GUU87_RS13255 ENOG4105HHA aminodeoxychorismate lyase GUU87_RS13260 ENOG4105YAZ 4-amino-4-deoxychorismate lyase GUU87_RS13265 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GUU87_RS13270 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GUU87_RS13275 ENOG4105CHR reductase GUU87_RS13280 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase GUU87_RS13300 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein GUU87_RS13305 ENOG4108UHJ MAF-like protein GUU87_RS13310 ENOG4105EI2 Pseudouridine synthase GUU87_RS13315 ENOG4107QQB Ribonuclease E GUU87_RS13320 ENOG4105DTJ flagellar hook-associated protein GUU87_RS13325 ENOG4105E1Q flagellar hook-associated protein GUU87_RS13330 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj GUU87_RS13345 ENOG4105CGA flagellar basal-body rod protein FlgG GUU87_RS13350 ENOG4108KPB Flagellar basal-body rod protein FlgF GUU87_RS13355 ENOG4105BZE flagellar hook protein, FlgE GUU87_RS13360 ENOG4105W00 Flagellar hook capping protein GUU87_RS13365 ENOG4108ZC9 flagellar basal-body rod protein flgc GUU87_RS13370 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) GUU87_RS13375 ENOG4105CKS Flagella basal body P-ring formation protein flgA GUU87_RS13380 ENOG4105M9M anti-sigma28 factor FlgM GUU87_RS13385 ENOG4105QVD Flagella synthesis protein FlgN GUU87_RS13390 ENOG4105CJR Integral membrane protein (MviN GUU87_RS13395 ENOG4105EP9 oxidoreductase GUU87_RS13405 ENOG4105D9U N-acetyltransferase GUU87_RS13415 ENOG4105E9S glutaredoxin 2 GUU87_RS13420 ENOG4105F3T (LipO)protein GUU87_RS13430 ENOG4105MEA DNA damage-inducible protein i GUU87_RS13435 ENOG4105PVA Biofilm formation regulatory protein BssS GUU87_RS13445 ENOG4106974 biofilm formation GUU87_RS13450 ENOG4105DS1 cytochrome b561 GUU87_RS13455 ENOG4108YYC ycei family GUU87_RS13465 ENOG4105D1S lipid A biosynthesis GUU87_RS13475 ENOG4108W47 Acidic protein msyB GUU87_RS13480 ENOG4105NAC (LipO)protein GUU87_RS13485 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) GUU87_RS13500 ENOG4107RZC phospholipase d GUU87_RS13505 ENOG4108UVJ appr-1-p processing domain protein GUU87_RS13520 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin GUU87_RS13525 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers GUU87_RS13530 ENOG41086KC Transcriptional regulator GUU87_RS13535 ENOG4108XDW curli assembly protein CsgE GUU87_RS13540 ENOG4108WYR Curli production assembly transport component, CsgF GUU87_RS13545 ENOG4105P8Q Curli production assembly transport component CsgG GUU87_RS13550 ENOG4108UQ5 membrane protein YcdZ GUU87_RS13555 ENOG4107XHZ cytoplasmic chaperone TorD family protein GUU87_RS13580 ENOG4105D5M phosphate starvation-inducible protein GUU87_RS13585 ENOG4105DBE peroxidase GUU87_RS13590 ENOG410650H (LipO)protein GUU87_RS13595 ENOG4105EKT )-iron permease GUU87_RS13600 ENOG4105CK7 Sodium proline symporter GUU87_RS13610 ENOG4105C26 Dehydrogenase GUU87_RS13615 ENOG4108R86 Transcriptional regulator GUU87_RS13625 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) GUU87_RS13640 ENOG4108RDT NADH dehydrogenase NAD(P)H nitroreductase) GUU87_RS13650 ENOG4105C2W permease GUU87_RS13655 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 GUU87_RS13665 ENOG4105XH3 GUU87_RS13670 ENOG4105D6F Phosphatase GUU87_RS13700 ENOG4108J2R molybdopterin oxidoreductase GUU87_RS13705 ENOG4105CUW cytochrome C-TYPE protein GUU87_RS13710 ENOG4106WF9 DNA-binding transcriptional regulator TorR GUU87_RS13715 ENOG4108SV3 Tmao reductase system periplasmic protein tort GUU87_RS13720 ENOG4105BZU Histidine kinase GUU87_RS13725 ENOG4105HEE Binding Domain protein GUU87_RS13730 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation GUU87_RS13745 ENOG4105VEQ Cold shock protein GUU87_RS13750 ENOG41060EU Cold shock-like protein GUU87_RS13760 ENOG4108Y9B (LipO)protein GUU87_RS13765 ENOG4108W78 Pfam:DUF1017 GUU87_RS13770 ENOG4105E3R (LipO)protein GUU87_RS13775 ENOG4105DAY polysaccharide export protein GUU87_RS13780 ENOG4107ZF2 Phosphatase GUU87_RS13785 ENOG4105D75 Capsular exopolysaccharide family GUU87_RS13790 ENOG4105D6F Phosphatase GUU87_RS13800 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GUU87_RS13805 ENOG4105C4M (Ubiquinol oxidase) subunit I GUU87_RS13810 ENOG4105MVP hydrogenase-1 operon protein HyaF GUU87_RS13815 ENOG4108VXY Hydrogenase-1 operon protein HyaE GUU87_RS13820 ENOG4108USZ hydrogenase GUU87_RS13825 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit GUU87_RS13830 ENOG4105DPX Hydrogenase, large subunit GUU87_RS13835 ENOG4105E3S small subunit GUU87_RS13845 ENOG4108MN8 Membrane GUU87_RS13850 ENOG4108Z0T Part of a sulfur-relay system (By similarity) GUU87_RS13855 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 GUU87_RS13870 ENOG4105K4P CoA-binding domain protein GUU87_RS13885 ENOG41088T4 Helicase IV GUU87_RS13890 ENOG410901E Membrane GUU87_RS13895 ENOG4105EM2 membrane GUU87_RS13900 ENOG4108RZ1 DNA transformation protein GUU87_RS13910 ENOG4105UYK outer membrane protein a GUU87_RS13920 ENOG4105DAN ATP-dependent protease GUU87_RS13930 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) GUU87_RS13935 ENOG4108Q2G (LipO)protein GUU87_RS13940 ENOG4105DY2 Paraquat-inducible protein b GUU87_RS13945 ENOG4105F1S paraquat-inducible protein a GUU87_RS13950 ENOG4105C5H ABC transporter GUU87_RS13955 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) GUU87_RS13960 ENOG4105QVC MOSC domain-containing protein GUU87_RS13965 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) GUU87_RS13975 ENOG4106PH7 chaperone GUU87_RS13980 ENOG4105MX3 Fimbrial GUU87_RS13985 ENOG4105Q7J Fimbrial GUU87_RS13990 ENOG4108MDY Fimbrial GUU87_RS13995 ENOG4105CW0 outer membrane usher protein GUU87_RS14000 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae GUU87_RS14005 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon GUU87_RS14010 ENOG4108UZX fmn reductase GUU87_RS14015 ENOG4105GVF (ABC) transporter GUU87_RS14025 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component GUU87_RS14035 ENOG4105CD8 aminopeptidase N GUU87_RS14050 ENOG4105FCK Membrane GUU87_RS14055 ENOG4105CGF Aromatic amino acid aminotransferase GUU87_RS14060 ENOG4105C5X domain protein GUU87_RS14065 ENOG4105EAQ (twin-arginine translocation) pathway signal GUU87_RS14070 ENOG4105DIT ErfK YbiS YcfS YnhG family protein GUU87_RS14075 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) GUU87_RS14080 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) GUU87_RS14090 ENOG4106371 Methyltransferase GUU87_RS14095 ENOG4107S90 membrAne GUU87_RS14100 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups GUU87_RS14115 ENOG4105T0Z Conserved Protein GUU87_RS14125 ENOG4105BZ1 (ABC) transporter GUU87_RS14130 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 GUU87_RS14140 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) GUU87_RS14150 ENOG4108K0D peptidase, M48 GUU87_RS14165 ENOG4107VMU Membrane GUU87_RS14170 ENOG4105DDY UPF0142 protein ycaO GUU87_RS14175 ENOG4105TMB Formate nitrite transporter GUU87_RS14180 ENOG4105C6N Formate acetyltransferase GUU87_RS14185 ENOG4105F1A Pyruvate formate-lyase GUU87_RS14190 ENOG4108X0B nad(p)h dehydrogenase (quinone) GUU87_RS14195 ENOG410642W LysR family Transcriptional regulator GUU87_RS14200 ENOG4105E5D amino acid GUU87_RS14210 ENOG4105CHJ isochorismatase hydrolase GUU87_RS14215 ENOG4107KGK dmso reductase anchor subunit GUU87_RS14220 ENOG4105QAX Iron-sulfur GUU87_RS14225 ENOG4107QY8 reductase GUU87_RS14235 ENOG4105D1H recombination factor protein RarA GUU87_RS14245 ENOG4105CNU cell division protein FtsK GUU87_RS14250 ENOG4105EW9 transcriptional regulator AsnC family GUU87_RS14255 ENOG4105C3M thioredoxin reductase GUU87_RS14260 ENOG4108JJ9 ABC, transporter GUU87_RS14265 ENOG4108JJ8 (ABC) transporter GUU87_RS14275 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) GUU87_RS14285 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GUU87_RS14295 ENOG4105VEQ Cold shock protein GUU87_RS14300 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) GUU87_RS14305 ENOG4105DJY efflux transporter, rnd family, mfp subunit GUU87_RS14310 ENOG4108MJ5 VirK protein GUU87_RS14315 ENOG4105CPB ATP-dependent endonuclease of the OLD family GUU87_RS14320 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) GUU87_RS14325 ENOG4105DWU Membrane GUU87_RS14335 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GUU87_RS14340 ENOG4105C7K acetolactate synthase GUU87_RS14345 ENOG4105C5W Aldolase GUU87_RS14350 ENOG4105CGD Nad-dependent epimerase dehydratase GUU87_RS14355 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase GUU87_RS14360 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase GUU87_RS14370 ENOG41064MM (LipO)protein GUU87_RS14375 ENOG4105E5Z arginine transporter ATP-binding subunit GUU87_RS14380 ENOG4106PMH Extracellular solute-binding protein family 3 GUU87_RS14385 ENOG4105GBT ABC transporter GUU87_RS14390 ENOG4105DMR ABC, transporter GUU87_RS14395 ENOG4106TNF Periplasmic binding protein GUU87_RS14405 ENOG4105RBQ inner membrane protein ybjO GUU87_RS14410 ENOG4105D38 putrescine abc transporter GUU87_RS14415 ENOG4105F38 ABC transporter, permease GUU87_RS14420 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GUU87_RS14425 ENOG4107RUE extracellular solute-binding protein family 1 GUU87_RS14430 ENOG4108RMJ sensory transduction regulator GUU87_RS14440 ENOG4108DBC nitroreductase GUU87_RS14445 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress GUU87_RS14450 ENOG41090BQ Glutaredoxin GUU87_RS14455 ENOG4105GWF inner membrane protein YbjM GUU87_RS14465 ENOG4105ZTC transcriptional activator, Ogr delta GUU87_RS14505 ENOG4108C33 Resolvase GUU87_RS14515 ENOG4105PTU response to oxidative stress GUU87_RS14520 ENOG4108US3 tail fiber assembly GUU87_RS14610 ENOG4105ED4 portal protein GUU87_RS14635 ENOG4105VZ1 Replication Protein GUU87_RS14640 ENOG4105DFE Dna adenine methylase GUU87_RS14645 ENOG4105KSC Transcriptional regulator, TraR DksA family GUU87_RS14670 ENOG4105MEH GUU87_RS14690 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GUU87_RS14700 ENOG4108RFG Tetr family transcriptional regulator GUU87_RS14705 ENOG4106UW1 Major Facilitator superfamily GUU87_RS14710 ENOG4108HCJ Hydrolase GUU87_RS14720 ENOG4107QF7 multi-drug GUU87_RS14725 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase GUU87_RS14730 ENOG4107FB0 transcriptional regulator DeoR family GUU87_RS14735 ENOG4105DZ1 carboxypeptidase GUU87_RS14740 ENOG4108TGY Glutathione S-transferase GUU87_RS14745 ENOG4105D8V Glucose sorbosone dehydrogenase GUU87_RS14750 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway GUU87_RS14760 ENOG41064RH membrane protein YliF GUU87_RS14765 ENOG4105BZU Histidine kinase GUU87_RS14770 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GUU87_RS14790 ENOG4105D44 asparaginase GUU87_RS14795 ENOG4105CVM Molybdenum cofactor synthesis domain protein GUU87_RS14800 ENOG4105D06 uba thif-type nad fad binding protein GUU87_RS14805 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GUU87_RS14810 ENOG4105F1A Pyruvate formate-lyase GUU87_RS14815 ENOG4105C6N Formate acetyltransferase GUU87_RS14820 ENOG4108HCJ Hydrolase GUU87_RS14825 ENOG41072TH Protein of unknown function (DUF1479) GUU87_RS14835 ENOG4105C5H ABC transporter GUU87_RS14840 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GUU87_RS14845 ENOG4105F4P )-transporter GUU87_RS14850 ENOG4105KST dependent repressor GUU87_RS14860 ENOG4108I6E Sulfatase GUU87_RS14865 ENOG4108T1M outer membrane protein x GUU87_RS14875 ENOG4107AQZ Membrane GUU87_RS14885 ENOG4107R0W ABC transporter GUU87_RS14890 ENOG4105E5Q amino acid AbC transporter GUU87_RS14895 ENOG4105CDA abc transporter atp-binding protein GUU87_RS14900 ENOG4105D8X mechanosensitive ion channel GUU87_RS14910 ENOG4105ZY9 UPF0379 protein ybiM GUU87_RS14915 ENOG4108IU3 tonb-dependent siderophore receptor GUU87_RS14925 ENOG4105KSC Transcriptional regulator, TraR DksA family GUU87_RS14930 ENOG4105VR4 UPF0379 protein ybiJ GUU87_RS14935 ENOG4105DG4 malate L-lactate dehydrogenase GUU87_RS14940 ENOG4108MTB glycosyl transferase family GUU87_RS14945 ENOG4105DVT helicase GUU87_RS14950 ENOG4108UV1 cellular component movement GUU87_RS14955 ENOG4105C1J atp-dependent rna helicase GUU87_RS14960 ENOG4107MVR Transcriptional regulator GUU87_RS14970 ENOG4105CJ1 ABC, transporter GUU87_RS14975 ENOG4107QWP ABC-2 type transporter GUU87_RS14980 ENOG4107QWP ABC-2 type transporter GUU87_RS14985 ENOG4105I9U inner membrane protein ybhQ GUU87_RS14990 ENOG4105X23 Endonuclease Exonuclease phosphatase GUU87_RS14995 ENOG4105DZQ phospholipase D Transphosphatidylase GUU87_RS15000 ENOG4107UXM Membrane GUU87_RS15005 ENOG410733J conserved inner membrane protein GUU87_RS15015 ENOG4105HFZ Membrane GUU87_RS15020 ENOG4108ZAF Molybdopterin GUU87_RS15025 ENOG4105M00 molybdopterin converting factor, subunit 1 GUU87_RS15035 ENOG4108RIR Molybdenum cofactor biosynthesis protein GUU87_RS15045 ENOG4105CHW UPF0052 protein GUU87_RS15055 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) GUU87_RS15060 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GUU87_RS15075 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) GUU87_RS15080 ENOG4108V1U phospholipid-binding protein GUU87_RS15085 ENOG4106KTS Inner membrane protein yeaI GUU87_RS15090 ENOG4105UZW Tail fiber assembly protein GUU87_RS15095 ENOG4108X9F tail fiber protein GUU87_RS15170 ENOG4105IM0 capsid protein GUU87_RS15180 ENOG4105F7J membrane-bound serine protease GUU87_RS15190 ENOG4107DE1 head-to-tail joining protein GUU87_RS15195 ENOG4105UZW Tail fiber assembly protein GUU87_RS15200 ENOG4105FKG DNA packaging protein GUU87_RS15205 ENOG4106YSC GUU87_RS15210 ENOG41064WM Uncharacterized protein YcgX GUU87_RS15225 ENOG4105KUS lysozyme GUU87_RS15230 ENOG4105QFS Lysis protein S homolog from lambdoid prophage GUU87_RS15240 ENOG4105HRS Antitermination protein GUU87_RS15285 ENOG4105NY2 NinB protein GUU87_RS15405 ENOG4108I1J Integrase GUU87_RS15410 ENOG4105NBR Pectinesterase GUU87_RS15415 ENOG4107QM5 aconitate hydratase GUU87_RS15420 ENOG4107QPK )-transporter GUU87_RS15425 ENOG4105C7F AcnD-accessory protein PrpF GUU87_RS15430 ENOG4105F04 LysR family Transcriptional regulator GUU87_RS15440 ENOG4108K4B hydrolase GUU87_RS15445 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) GUU87_RS15450 ENOG4105E0C molybdate abc transporter GUU87_RS15455 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein GUU87_RS15460 ENOG410680R Protein of unknown function (DUF2592) GUU87_RS15465 ENOG4105F4R Transcriptional regulator mode GUU87_RS15470 ENOG4105DKW ABC transporter GUU87_RS15475 ENOG4105CMR udp-glucose 4-epimerase GUU87_RS15480 ENOG4105F0Z galactose-1-phosphate uridylyltransferase GUU87_RS15490 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) GUU87_RS15500 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GUU87_RS15505 ENOG4105JND homeobox protein GUU87_RS15510 ENOG4105PGM cation diffusion facilitator family transporter GUU87_RS15515 ENOG4106Z1T Nicotinamide Mononucleotide Transporter GUU87_RS15565 ENOG4105UFD tol-pal system protein YbgF GUU87_RS15570 ENOG4105KCK Peptidoglycan-associated lipoprotein GUU87_RS15580 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA GUU87_RS15585 ENOG4105M8F Biopolymer transport protein exbD tolR GUU87_RS15590 ENOG4105E02 MotA TolQ exbB proton channel GUU87_RS15595 ENOG4107YD3 Thioesterase GUU87_RS15600 ENOG4105KJB cyd operon protein YbgE GUU87_RS15610 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GUU87_RS15615 ENOG4105C4M (Ubiquinol oxidase) subunit I GUU87_RS15620 ENOG4105C8I hydrolase, family 38 GUU87_RS15625 ENOG4105DM4 PTS System GUU87_RS15630 ENOG4105FDP GntR family transcriptional regulator GUU87_RS15635 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha GUU87_RS15645 ENOG4105C7S Dehydrogenase GUU87_RS15650 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 GUU87_RS15655 ENOG4105E33 succinate dehydrogenase GUU87_RS15660 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) GUU87_RS15665 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein GUU87_RS15670 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit GUU87_RS15680 ENOG4105BZN citrate synthase GUU87_RS15685 ENOG4106UBK fimbrial-like adhesin protein GUU87_RS15690 ENOG4106PG1 outer membrane usher protein GUU87_RS15695 ENOG4108TTM chaperone GUU87_RS15700 ENOG4108MY7 Fimbrial GUU87_RS15705 ENOG4108KK1 membrane protein AbrB duplication GUU87_RS15715 ENOG4105E7W lamb ycsf family protein GUU87_RS15720 ENOG4107R7A Allophanate hydrolase subunit 2 GUU87_RS15725 ENOG4105P4J Allophanate hydrolase, subunit 1 GUU87_RS15730 ENOG4107QNR UPF0135 protein GUU87_RS15735 ENOG4105DUX Transporter GUU87_RS15740 ENOG4105CVP deoxyribo-dipyrimidine photolyase GUU87_RS15745 ENOG4107SEY Conserved Protein GUU87_RS15760 ENOG4106R09 GUU87_RS15770 ENOG41079JQ Membrane GUU87_RS15775 ENOG4105CNA YD repeat protein GUU87_RS15780 ENOG4105XIQ Protein of unknown function (DUF2517) GUU87_RS15805 ENOG4105C08 Histidine kinase GUU87_RS15810 ENOG4105EEX Two component transcriptional regulator (Winged helix family GUU87_RS15820 ENOG4105CXN decarboxylase GUU87_RS15825 ENOG4105D5Q Arginine ornithine antiporter GUU87_RS15830 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 GUU87_RS15835 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) GUU87_RS15840 ENOG4105EV9 Alpha Beta Hydrolase GUU87_RS15845 ENOG4105NNH LexA regulated protein GUU87_RS15850 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) GUU87_RS15860 ENOG41090R7 Ferric uptake GUU87_RS15865 ENOG4105GX6 (LipO)protein GUU87_RS15880 ENOG4105CI1 PTS System GUU87_RS15890 ENOG4105CE4 GlcNAc 6-P deacetylase GUU87_RS15895 ENOG4105E2R ROK family GUU87_RS15900 ENOG4105D4U had-superfamily hydrolase, subfamily iia GUU87_RS15905 ENOG4105CAQ asparagine synthetase GUU87_RS15945 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family GUU87_RS15955 ENOG4105C9A Phoh family GUU87_RS15965 ENOG4108JU5 Magnesium and cobalt efflux protein GUU87_RS15970 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) GUU87_RS15975 ENOG4107U91 Rhomboid family GUU87_RS15980 ENOG4107RP9 extracellular solute-binding protein, family 3 GUU87_RS15985 ENOG4105EAD ABC transporter GUU87_RS15990 ENOG4105DRP amino acid AbC transporter GUU87_RS15995 ENOG4105CDA abc transporter atp-binding protein GUU87_RS16005 ENOG4105F7F Chaperone GUU87_RS16010 ENOG4105QFC Hsc56 co-chaperone of HscC GUU87_RS16015 ENOG41069CF Protein of unknown function (DUF1266) GUU87_RS16020 ENOG4107JFD Sel1 repeat GUU87_RS16025 ENOG4105QFC Hsc56 co-chaperone of HscC GUU87_RS16035 ENOG4105EUU Sel1 domain protein repeat-containing protein GUU87_RS16055 ENOG4105DJF DNA polymerase III, delta' subunit GUU87_RS16065 ENOG4108TGR phosphatase GUU87_RS16070 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) GUU87_RS16080 ENOG4105CJN penicillin-binding protein GUU87_RS16085 ENOG4105CNI cell division protein FtsW GUU87_RS16090 ENOG4105K6T rare lipoprotein A GUU87_RS16095 ENOG4105DZ1 carboxypeptidase GUU87_RS16110 ENOG41064T2 transcriptional regulator, lysR family GUU87_RS16120 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) GUU87_RS16125 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GUU87_RS16135 ENOG4105VEQ Cold shock protein GUU87_RS16140 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) GUU87_RS16145 ENOG4105CEE C4-dicarboxylate transporter GUU87_RS16150 ENOG4106YYS transcriptional regulatory protein GUU87_RS16155 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism GUU87_RS16160 ENOG4105DUA (citrate (pro-3S)-lyase ligase GUU87_RS16170 ENOG4105CI0 Citrate lyase GUU87_RS16175 ENOG4105CHY citrate lyase, alpha GUU87_RS16190 ENOG4107QPK )-transporter GUU87_RS16195 ENOG4105KTS ribonuclease GUU87_RS16200 ENOG4105NXH GreA GreB family elongation factor GUU87_RS16205 ENOG4105E2A Dehydrogenase GUU87_RS16210 ENOG4108U51 Universal stress protein GUU87_RS16215 ENOG4108JU3 Alkyl hydroperoxide reductase GUU87_RS16220 ENOG4105D3R alkyl hydroperoxide reductase GUU87_RS16225 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase GUU87_RS16230 ENOG4105DQS Transcriptional regulator GUU87_RS16235 ENOG4105BZV Phosphoadenosine phosphosulfate reductase GUU87_RS16240 ENOG4105GTN ParB Domain Protein Nuclease GUU87_RS16245 ENOG4105CHM Aminotransferase GUU87_RS16250 ENOG4107SCQ Iron-containing alcohol dehydrogenase GUU87_RS16255 ENOG4105VCD cytoplasmic protein GUU87_RS16260 ENOG4105D22 carbon starvation protein GUU87_RS16265 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) GUU87_RS16270 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase GUU87_RS16275 ENOG4105WQI isochorismatase GUU87_RS16280 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase GUU87_RS16285 ENOG4105E4F Isochorismate synthase GUU87_RS16290 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein GUU87_RS16300 ENOG4105DQ5 transport system permease protein GUU87_RS16305 ENOG4105TVJ transport system, permease GUU87_RS16310 ENOG4105E0A ABC, transporter GUU87_RS16315 ENOG4108QY5 Ferric enterobactin transport protein GUU87_RS16320 ENOG4105C0W non-ribosomal peptide synthetase GUU87_RS16325 ENOG41085A6 mbth domain-containing protein GUU87_RS16330 ENOG4105E93 esterase GUU87_RS16335 ENOG4107RNH Outer membrane receptor FepA GUU87_RS16340 ENOG4108TSE Transferase GUU87_RS16345 ENOG4107635 Hok Gef family protein GUU87_RS16350 ENOG4107635 Hok Gef family protein GUU87_RS16360 ENOG4105WQ6 Membrane GUU87_RS16365 ENOG4105MSB protein, conserved in bacteria GUU87_RS16370 ENOG4108RCM Nitroreductase GUU87_RS16375 ENOG4105CUY Mechanosensitive ion channel GUU87_RS16380 ENOG4105C85 amino acid GUU87_RS16385 ENOG4108IJF Heavy metal efflux pump, CzcA GUU87_RS16390 ENOG4105EP1 Efflux transporter rnd family, mfp subunit GUU87_RS16395 ENOG410624V efflux system protein GUU87_RS16400 ENOG4105ENJ RND efflux system, outer membrane lipoprotein GUU87_RS16405 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GUU87_RS16410 ENOG4105GR3 Histidine kinase GUU87_RS16415 ENOG4105CS6 Rhs element vgr protein GUU87_RS16425 ENOG4105CNA YD repeat protein GUU87_RS16440 ENOG410600T transposase GUU87_RS16445 ENOG410802X bacteriophage n4 adsorption protein b GUU87_RS16450 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit GUU87_RS16455 ENOG4105QUW GUU87_RS16470 ENOG4108Q9V regulatoR GUU87_RS16475 ENOG4108ZI2 Fimbrial protein GUU87_RS16480 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) GUU87_RS16490 ENOG4108AF8 Chaperone GUU87_RS16495 ENOG4108WDE Fimbrial protein GUU87_RS16505 ENOG4105WQ3 Rna-binding protein GUU87_RS16510 ENOG4105S2T inner membrane protein YbcI GUU87_RS16520 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) GUU87_RS16530 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) GUU87_RS16535 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit GUU87_RS16540 ENOG4105C5B carbamate kinase GUU87_RS16545 ENOG4105G5A Protein of unknown function (DUF2877) GUU87_RS16550 ENOG4107REC cytoplasmic protein GUU87_RS16555 ENOG4107R1Q Membrane protein FdrA GUU87_RS16560 ENOG4105DG4 malate L-lactate dehydrogenase GUU87_RS16565 ENOG4105CE7 Amidase, hydantoinase carbamoylase family GUU87_RS16570 ENOG4105S0E allantoin catabolism protein GUU87_RS16575 ENOG4105BZW Glycerate kinase GUU87_RS16580 ENOG4105DTE Xanthine uracil vitamin C permease GUU87_RS16590 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease GUU87_RS16595 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GUU87_RS16600 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) GUU87_RS16605 ENOG41060W2 glyoxylate carboligase GUU87_RS16610 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region GUU87_RS16615 ENOG4108Z2U ureidoglycolate hydrolase GUU87_RS16620 ENOG4107653 Transcriptional regulator GUU87_RS16630 ENOG4105CV6 ABC transporter, permease GUU87_RS16635 ENOG4108I0Y (ABC) transporter GUU87_RS16640 ENOG4108UJV acyl-CoA thioesterase i GUU87_RS16645 ENOG4105E1F short-chain dehydrogenase reductase GUU87_RS16650 ENOG4107QR8 Thioredoxin GUU87_RS16655 ENOG4105C4B ABC transporter, permease GUU87_RS16660 ENOG41083J0 (ABC) transporter GUU87_RS16665 ENOG4107QX8 SPFH domain, Band 7 family protein GUU87_RS16670 ENOG4105G5H Membrane GUU87_RS16675 ENOG4108Z6Z Transcriptional regulator GUU87_RS16680 ENOG4107RY6 amino acid GUU87_RS16685 ENOG4105CSV Glutaminase GUU87_RS16690 ENOG4105C59 p-type ATPase GUU87_RS16695 ENOG41081XE plasmid maintenance system antidote protein, xre family GUU87_RS16700 ENOG4105MBR gumn family GUU87_RS16705 ENOG4108Z66 YbaK ebsC protein GUU87_RS16710 ENOG4105CGH 5'-nucleotidase GUU87_RS16715 ENOG4105EU0 Major facilitator Superfamily GUU87_RS16720 ENOG4105CKD glutathione-regulated potassium-efflux system protein GUU87_RS16725 ENOG4107RE1 Inosine-guanosine kinase GUU87_RS16760 ENOG4107QMP dna polymerase iii subunits gamma and tau GUU87_RS16770 ENOG4105WD1 Membrane GUU87_RS16775 ENOG4108URS primosomal replication protein n'' GUU87_RS16780 ENOG4106428 Protein of unknown function (DUF2496) GUU87_RS16785 ENOG4105EGS Mechanosensitive ion channel GUU87_RS16790 ENOG4108IG5 Transcriptional regulator GUU87_RS16795 ENOG4105C1P efflux transporter, rnd family, mfp subunit GUU87_RS16800 ENOG4105BZS acriflavin resistance protein GUU87_RS16805 ENOG4108UKR Biofilm formation regulator YbaJ GUU87_RS16810 ENOG4105KF5 hemolysin expression-modulating protein GUU87_RS16815 ENOG4108UW5 maltose o-acetyltransferase GUU87_RS16820 ENOG4105GSJ Inner membrane protein ylaC GUU87_RS16825 ENOG41066DG (EAL) domain protein GUU87_RS16830 ENOG4105KCV RNA signal recognition particle 4.5S RNA GUU87_RS16840 ENOG41080UX Methyltransferase GUU87_RS16845 ENOG4108MNP Glycoprotein polysaccharide metabolism GUU87_RS16850 ENOG4105C29 acyl-CoA thioesterase GUU87_RS16855 ENOG4105BZU Histidine kinase GUU87_RS16860 ENOG4108YZA Nitrogen regulatory protein pii GUU87_RS16865 ENOG4105BZ1 (ABC) transporter GUU87_RS16870 ENOG4105BZ1 (ABC) transporter GUU87_RS16875 ENOG4108XM1 transcriptional regulator AsnC family GUU87_RS16885 ENOG4108NFA extracellular solute-binding protein GUU87_RS16895 ENOG4108TGP Thioesterase superfamily protein GUU87_RS16900 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein GUU87_RS16905 ENOG4105EIN peptidylprolyl cis-trans isomerase GUU87_RS16910 ENOG4105K70 DNA-binding protein GUU87_RS16915 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) GUU87_RS16935 ENOG4105M85 Bola protein GUU87_RS16940 ENOG4105IEY (LipO)protein GUU87_RS16945 ENOG4105EYM Major Facilitator superfamily GUU87_RS16950 ENOG4105E2S oxidase) subunit II GUU87_RS16955 ENOG4105BZ9 Cytochrome C oxidase, subunit I GUU87_RS16960 ENOG4105CCU oxidase (Subunit III) GUU87_RS16965 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) GUU87_RS16990 ENOG4107RDB Major Facilitator GUU87_RS17000 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) GUU87_RS17005 ENOG4107S0N DJ-1 family GUU87_RS17020 ENOG4105CTB Polyprenyl synthetase GUU87_RS17030 ENOG4105CPC Aldo Keto reductase GUU87_RS17035 ENOG4108ZAI phosphatidylglycerophosphatase a GUU87_RS17040 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) GUU87_RS17050 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) GUU87_RS17055 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) GUU87_RS17065 ENOG4108KIC (LipO)protein GUU87_RS17070 ENOG4105DRB nucleoside-specific channel-forming protein GUU87_RS17075 ENOG4105N1F Hnh endonuclease GUU87_RS17080 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) GUU87_RS17085 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) GUU87_RS17090 ENOG4105VIE preprotein translocase, subunit YajC GUU87_RS17110 ENOG4107R28 alpha amylase, catalytic region GUU87_RS17115 ENOG4105C85 amino acid GUU87_RS17120 ENOG4105CWM branched-chain amino acid transport system II carrier protein GUU87_RS17125 ENOG4105BZU Histidine kinase GUU87_RS17130 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GUU87_RS17135 ENOG4107RH8 nuclease SbcCD subunit D GUU87_RS17140 ENOG4105EYH Exonuclease GUU87_RS17145 ENOG4105F27 Major Facilitator GUU87_RS17150 ENOG4105DKQ ROK family GUU87_RS17175 ENOG4105HBA AroM protein GUU87_RS17180 ENOG4105SS3 GUU87_RS17195 ENOG4105II7 pyrroline-5-carboxylate reductase GUU87_RS17200 ENOG4105BZU Histidine kinase GUU87_RS17205 ENOG4105VIF phosphate starvation-inducible protein GUU87_RS17210 ENOG4105G6Z alkaline phosphatase GUU87_RS17220 ENOG4105CPF Cell wall formation (By similarity) GUU87_RS17225 ENOG4105UNH Membrane GUU87_RS17230 ENOG4105FR5 inner membrane protein YaiY GUU87_RS17235 ENOG4107QS8 (LipO)protein GUU87_RS17240 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 GUU87_RS17245 ENOG4107R6D beta-lactam binding protein AmpH GUU87_RS17250 ENOG4108PNB DNA-binding transcriptional regulator GUU87_RS17260 ENOG4105D52 delta-aminolevulinic acid dehydratase GUU87_RS17265 ENOG4105E2B Taurine dioxygenase GUU87_RS17270 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component GUU87_RS17275 ENOG4108IY8 ABC, transporter GUU87_RS17280 ENOG4106FTQ Taurine ABC transporter, periplasmic GUU87_RS17285 ENOG4107W19 lmbE family GUU87_RS17290 ENOG4108PBI Polysaccharide metabolism GUU87_RS17300 ENOG4105SRB Uncharacterized protein yaiO GUU87_RS17320 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme GUU87_RS17325 ENOG4108SC4 )-transporter GUU87_RS17360 ENOG4108K2P TRANSCRIPTIONal GUU87_RS17365 ENOG4105ETE Transcriptional regulator (LacI family GUU87_RS17375 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) GUU87_RS17380 ENOG4108UW5 maltose o-acetyltransferase GUU87_RS17385 ENOG4105DJ2 Major Facilitator Superfamily GUU87_RS17395 ENOG4107B2H carbonic anhydrase GUU87_RS17405 ENOG4105DZC cytosine deaminase GUU87_RS17410 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin GUU87_RS17415 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GUU87_RS17420 ENOG4105DXD 2-methylcitrate dehydratase GUU87_RS17425 ENOG4105BZN citrate synthase GUU87_RS17430 ENOG4105CR4 methylisocitrate lyase GUU87_RS17435 ENOG4108JU7 Transcriptional regulator GUU87_RS17440 ENOG4105TDT uncharacterized protein yahO GUU87_RS17445 ENOG4105E82 cytochrome subunit of dehydrogenase GUU87_RS17460 ENOG4105DQ4 alcohol dehydrogenase GUU87_RS17465 ENOG4105CNN ABC, transporter GUU87_RS17470 ENOG4105CNN ABC, transporter GUU87_RS17475 ENOG4105C2J ABC transporter GUU87_RS17480 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator GUU87_RS17490 ENOG4105DZC cytosine deaminase GUU87_RS17495 ENOG4105C5B carbamate kinase GUU87_RS17500 ENOG4107REC cytoplasmic protein GUU87_RS17505 ENOG4107R1Q Membrane protein FdrA GUU87_RS17510 ENOG4105N16 Protein of unknown function (DUF2877) GUU87_RS17515 ENOG4107SNB ankyrin repeat protein YahD GUU87_RS17520 ENOG4105SZ2 membrAne GUU87_RS17525 ENOG4108NUU Transcriptional regulator GUU87_RS17530 ENOG4105BZU Histidine kinase GUU87_RS17540 ENOG4105C94 Transporter GUU87_RS17565 ENOG4108W9T type 1 fimbriae regulatory protein GUU87_RS17580 ENOG4105BZU Histidine kinase GUU87_RS17605 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) GUU87_RS17610 ENOG4107QR9 Iron-sulfur cluster binding protein GUU87_RS17615 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GUU87_RS17620 ENOG4108K01 transcriptional regulator GUU87_RS17625 ENOG4107QN2 dihydrolipoyl dehydrogenase GUU87_RS17630 ENOG41066GK UPF0379 protein ykgI GUU87_RS17635 ENOG4108KBJ Inner membrane protein YkgB GUU87_RS17640 ENOG4105CV8 reductase GUU87_RS17695 ENOG4108N3D putative enzyme GUU87_RS17700 ENOG4106PYX Receptor GUU87_RS17705 ENOG4108UD7 cell wall organization GUU87_RS17710 ENOG4105PI0 Ferredoxin GUU87_RS17715 ENOG4105R3P Inner membrane protein yagU GUU87_RS17720 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit GUU87_RS17725 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding GUU87_RS17730 ENOG4105C7W Xanthine dehydrogenase GUU87_RS17735 ENOG4107XAN XdhC and CoxI family GUU87_RS17760 ENOG4108C33 Resolvase GUU87_RS17780 ENOG4105Y0G tail protein GUU87_RS17785 ENOG4108T86 baseplate J family protein GUU87_RS17805 ENOG4108NKR DNA circulation protein GUU87_RS17825 ENOG4105TKZ Tail Sheath GUU87_RS17870 ENOG4105EFC phage portal protein HK97 family GUU87_RS17880 ENOG4105CAR Terminase, large subunit GUU87_RS17900 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 GUU87_RS17925 ENOG4105HRS Antitermination protein GUU87_RS17930 ENOG4108MXB Protein of unknown function (DUF968) GUU87_RS17945 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) GUU87_RS17960 ENOG4105YQ0 GUU87_RS17970 ENOG4108S1U GUU87_RS17975 ENOG41078CG DNA-binding transcriptional regulator GUU87_RS17980 ENOG4105RDA repressor GUU87_RS17995 ENOG4108R7K Metal Dependent Phosphohydrolase GUU87_RS18000 ENOG41077V0 CPS-53 (KpLE1) prophage GUU87_RS18015 ENOG4108KU3 Integrase GUU87_RS18035 ENOG4105FCK Membrane GUU87_RS18055 ENOG4105CIN aminoacyl-histidine dipeptidase GUU87_RS18060 ENOG4108S2Y peptide Chain Release factor GUU87_RS18070 ENOG4108HYG acetyltransferase GUU87_RS18100 ENOG4108YS0 lipoprotein YafL GUU87_RS18110 ENOG4105VXN addiction module toxin, RelE StbE family GUU87_RS18115 ENOG4105F7V ErfK ybiS ycfS ynhG family protein GUU87_RS18120 ENOG4105E7A Glutamine amidotransferase GUU87_RS18130 ENOG4107QPN acyl-Coa dehydrogenase GUU87_RS18135 ENOG4108WN0 inhibitor of vertebrate lysozyme GUU87_RS18140 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GUU87_RS18155 ENOG4105CNA YD repeat protein GUU87_RS18160 ENOG4105CS6 Rhs element vgr protein GUU87_RS18165 ENOG4108WC9 type VI secretion system effector, hcp1 family GUU87_RS18220 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GUU87_RS18245 ENOG4105GMB type VI secretion system effector, hcp1 family GUU87_RS18260 ENOG410600K aminopeptidase GUU87_RS18270 ENOG4107RZZ dna polymerase iii epsilon subunit GUU87_RS18280 ENOG4105D1A Methyltransferase GUU87_RS18290 ENOG4105E9H Lytic Murein transglycosylase GUU87_RS18295 ENOG4105F2W methyltransferase GUU87_RS18305 ENOG4105HEI LysR family (Transcriptional regulator GUU87_RS18310 ENOG4105CV8 reductase GUU87_RS18345 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase GUU87_RS18350 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) GUU87_RS18355 ENOG4108UMI ABC transporter, permease GUU87_RS18360 ENOG4105D01 (LipO)protein GUU87_RS18365 ENOG4108R8X outer membrane lipoprotein GUU87_RS18370 ENOG4108R96 Methyltransferase, YaeB family GUU87_RS18390 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion GUU87_RS18395 ENOG4108YZN class I peptide chain release factor GUU87_RS18400 ENOG4108VWS Yaeq family GUU87_RS18410 ENOG4105M1T rho-binding antiterminator GUU87_RS18415 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) GUU87_RS18420 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase GUU87_RS18425 ENOG4105CXN decarboxylase GUU87_RS18435 ENOG4105C0B DNA polymerase III (alpha subunit) GUU87_RS18460 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) GUU87_RS18465 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) GUU87_RS18475 ENOG4105DZP Membrane-associated zinc metalloprotease GUU87_RS18480 ENOG4105KNE Phosphatidate cytidylyltransferase GUU87_RS18485 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) GUU87_RS18490 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) GUU87_RS18515 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) GUU87_RS18535 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR GUU87_RS18540 ENOG4105C0H protease GUU87_RS18555 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) GUU87_RS18560 ENOG4105EN6 Membrane GUU87_RS18585 ENOG4105S6R Iron-hydroxamate transporter permease subunit GUU87_RS18590 ENOG4105J76 Periplasmic binding protein GUU87_RS18595 ENOG4105E0A ABC, transporter GUU87_RS18600 ENOG4105E0K tonB-dependent siderophore receptor GUU87_RS18605 ENOG4105BZ4 penicillin-binding protein GUU87_RS18610 ENOG4105CQ7 ATP-dependent helicase GUU87_RS18615 ENOG4107XID 2'-5' rna ligase GUU87_RS18625 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters GUU87_RS18630 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) GUU87_RS18635 ENOG4105DJ0 Poly(A) Polymerase GUU87_RS18640 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase GUU87_RS18650 ENOG4108VEV chaperone GUU87_RS18655 ENOG4105CW0 outer membrane usher protein GUU87_RS18660 ENOG4105CW0 outer membrane usher protein GUU87_RS18665 ENOG4108XEY fimbrial-like adhesin protein GUU87_RS18670 ENOG4105SYG Fimbrial protein GUU87_RS18675 ENOG4105SN2 fimbrial-like adhesin protein GUU87_RS18680 ENOG4105P0Q fimbrial-like protein YadC GUU87_RS18695 ENOG4108A32 Transposase GUU87_RS18705 ENOG4107BJW polysaccharide deacetylase GUU87_RS18710 ENOG4108YTN IIa component GUU87_RS18715 ENOG4105E3A (ABC) transporter GUU87_RS18720 ENOG4105DA5 (ABC) transporter GUU87_RS18725 ENOG41077A9 carbonic anhydrase GUU87_RS18730 ENOG4108UGV hypoxanthine phosphoribosyltransferase GUU87_RS18735 ENOG4105DZG Dehydrogenase GUU87_RS18745 ENOG4105E3B Multicopper oxidase GUU87_RS18750 ENOG4108ZRK uncharacterized protein yacC GUU87_RS18770 ENOG4107QIJ Aconitate hydratase 2 GUU87_RS18775 ENOG4108NST exported protein GUU87_RS18780 ENOG4107QN2 dihydrolipoyl dehydrogenase GUU87_RS18785 ENOG4107QSN dihydrolipoamide acetyltransferase GUU87_RS18790 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) GUU87_RS18795 ENOG41073TP transcriptional regulator GUU87_RS18800 ENOG4105C85 amino acid GUU87_RS18805 ENOG4106A72 regulatory protein AmpE GUU87_RS18810 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase GUU87_RS18815 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase GUU87_RS18820 ENOG4108ZUW Major pilin subunit GUU87_RS18825 ENOG4107QHF type ii secretion system protein e GUU87_RS18830 ENOG4105D7Q type ii secretion system GUU87_RS18840 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) GUU87_RS18855 ENOG4105M6F mutator MutT protein GUU87_RS18875 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) GUU87_RS18880 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) GUU87_RS18885 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) GUU87_RS18890 ENOG4105CPF Cell wall formation (By similarity) GUU87_RS18905 ENOG4105CNI cell division protein FtsW GUU87_RS18920 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) GUU87_RS18925 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) GUU87_RS18930 ENOG4105CJN penicillin-binding protein GUU87_RS18935 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) GUU87_RS18950 ENOG4107B7Y DNA-binding transcriptional regulator FruR GUU87_RS18960 ENOG4108ZP8 Acetolactate synthase small subunit GUU87_RS18965 ENOG4105C7K acetolactate synthase GUU87_RS18970 ENOG41064T2 transcriptional regulator, lysR family GUU87_RS18985 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) GUU87_RS19000 ENOG4105S8Q sugar efflux transporter GUU87_RS19015 ENOG4105DP9 ABC transporter GUU87_RS19020 ENOG4106SMU thiamine transporter membrane protein GUU87_RS19030 ENOG4108KF1 Membrane GUU87_RS19035 ENOG41063TF transcriptional regulator (AraC GUU87_RS19050 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase GUU87_RS19055 ENOG4105CQ2 DNA polymerase GUU87_RS19065 ENOG4105D3G Pseudouridine synthase GUU87_RS19070 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) GUU87_RS19075 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) GUU87_RS19080 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) GUU87_RS19105 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) GUU87_RS19120 ENOG4105C54 Major Facilitator superfamily GUU87_RS19125 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein GUU87_RS19130 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GUU87_RS19165 ENOG4106YT9 Enoyl-CoA hydratase GUU87_RS19175 ENOG4108XNW Transcriptional activatory protein CaiF GUU87_RS19180 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain GUU87_RS19185 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain GUU87_RS19205 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase GUU87_RS19220 ENOG4105DTN riboflavin biosynthesis protein ribF GUU87_RS19225 ENOG410647N response to DNA damage stimulus GUU87_RS19250 ENOG41063Z6 transcriptional regulator, lysR family GUU87_RS19260 ENOG4105WI6 cell killing protein encoded within cryptic prophage GUU87_RS19280 ENOG4108QUJ UPF0174 protein YaaW GUU87_RS19285 ENOG4106HK8 GPR1 FUN34 yaaH family protein GUU87_RS19290 ENOG4108RIR Molybdenum cofactor biosynthesis protein GUU87_RS19300 ENOG4105BZG amino acid carrier protein GUU87_RS19305 ENOG4105D1Q UPF0246 protein GUU87_RS19315 ENOG41062C6 Protein of unknown function (DUF2502) GUU87_RS19320 ENOG4105D98 threonine synthase GUU87_RS19330 ENOG4105CFH Aspartokinase GUU87_RS19340 ENOG4106FVC RNA methyltransferase GUU87_RS19345 ENOG410759A GUU87_RS19350 ENOG41065U4 response regulator GUU87_RS19355 ENOG4105CT7 inner membrane cred family protein GUU87_RS19360 ENOG4105EB3 Histidine kinase GUU87_RS19365 ENOG4105E3W Two component transcriptional regulator (Winged helix family GUU87_RS19370 ENOG4108RH0 Crea protein GUU87_RS19375 ENOG4105UEI Transcriptional Regulator AraC Family GUU87_RS19395 ENOG4107SC1 transglycosylase GUU87_RS19400 ENOG4105C5H ABC transporter GUU87_RS19405 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase GUU87_RS19410 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) GUU87_RS19415 ENOG4105EAC phosphoserine phosphatase GUU87_RS19420 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) GUU87_RS19450 ENOG4105G0K glycine radical enzyme YjjI family GUU87_RS19455 ENOG41076CZ activating enzyme GUU87_RS19460 ENOG4105EYA deoxyribonuclease GUU87_RS19465 ENOG4108NRW Phospholipase, patatin family GUU87_RS19475 ENOG4105K3G Periplasmic Protein GUU87_RS19485 ENOG4105PAD Hydrolase GUU87_RS19490 ENOG4105KEG ribosomal-protein-alanine acetyltransferase GUU87_RS19495 ENOG4108WPU DNA polymerase III subunit psi GUU87_RS19520 ENOG4105YBH Protein of unknown function (DUF1435) GUU87_RS19525 ENOG4108819 ferric iron reductase GUU87_RS19530 ENOG4108T94 DNA-binding transcriptional activator BglJ GUU87_RS19535 ENOG4108N8T regulatoR GUU87_RS19540 ENOG4105DWK Membrane GUU87_RS19555 ENOG4106CVF DNA replication protein GUU87_RS19560 ENOG4105RI1 glycoprotein receptor GUU87_RS19570 ENOG4105CPQ Dehydrogenase GUU87_RS19575 ENOG410617M Transcriptional regulator GUU87_RS19580 ENOG4108I5G Major Facilitator superfamily GUU87_RS19585 ENOG4105C8Q Methyl-accepting chemotaxis GUU87_RS19590 ENOG4108V8F Transcriptional regulator, MarR family GUU87_RS19595 ENOG4105ERH Fumarylacetoacetate hydrolase GUU87_RS19600 ENOG4105C26 Dehydrogenase GUU87_RS19605 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase GUU87_RS19635 ENOG4105EFA 4-hydroxyphenylacetate GUU87_RS19640 ENOG4107UWN reductase GUU87_RS19645 ENOG4105D22 carbon starvation protein GUU87_RS19650 ENOG4105VCD cytoplasmic protein GUU87_RS19655 ENOG4105CKI cobalamin synthesis protein GUU87_RS19665 ENOG4106DIZ Domain of unknown function (DUF1127) GUU87_RS19670 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GUU87_RS19680 ENOG41083G8 Multidrug resistance protein MdtM GUU87_RS19685 ENOG4106BRA Membrane GUU87_RS19690 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase GUU87_RS19695 ENOG4105CIZ coA-substrate-specific enzyme activase GUU87_RS19710 ENOG4105CBP Major Facilitator GUU87_RS19715 ENOG4105CBP Major Facilitator GUU87_RS19725 ENOG41074DU domain protein GUU87_RS19730 ENOG4108P2H Inner membrane protein YjiG GUU87_RS19735 ENOG4105DYB Isoaspartyl dipeptidase GUU87_RS19740 ENOG4107YNJ LysR family Transcriptional regulator GUU87_RS19760 ENOG4105C6F GntR Family Transcriptional Regulator GUU87_RS19765 ENOG4105DEI Mannitol dehydrogenase GUU87_RS19775 ENOG4107EFN gluconate transport system permease 3 GUU87_RS19780 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin GUU87_RS19785 ENOG4108T65 Fimbrial GUU87_RS19790 ENOG4108SQA Fimbrial GUU87_RS19795 ENOG4105CW0 outer membrane usher protein GUU87_RS19800 ENOG4108NAE Fimbrial chaperone protein GUU87_RS19805 ENOG4108S54 Fimbrial protein GUU87_RS19810 ENOG4108RQP Major type 1 subunit fimbrin GUU87_RS19815 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off GUU87_RS19820 ENOG4108W9T type 1 fimbriae regulatory protein GUU87_RS19825 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria GUU87_RS19950 ENOG4105C9U ATP-dependent DNA helicase RecQ GUU87_RS19980 ENOG4105DQ4 alcohol dehydrogenase GUU87_RS19985 ENOG4105D7A ATP-binding protein GUU87_RS19990 ENOG4108K5H permease YjgP YjgQ family protein GUU87_RS19995 ENOG4108M8S permease YjgP YjgQ family protein GUU87_RS20005 ENOG4105MYG DNA polymerase iii, chi subunit GUU87_RS20010 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) GUU87_RS20015 ENOG4108M3P Membrane GUU87_RS20020 ENOG4108MJ3 acetyltransferase GUU87_RS20025 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) GUU87_RS20050 ENOG4105XEP YhcH YjgK YiaL family protein GUU87_RS20055 ENOG4108XFH Transcriptional regulator GUU87_RS20060 ENOG4105F6U Short-chain dehydrogenase reductase Sdr GUU87_RS20065 ENOG4108UQ8 endoribonuclease L-psp GUU87_RS20070 ENOG41077AM PyrBI operon attenuator GUU87_RS20085 ENOG4105KME endoribonuclease L-psp GUU87_RS20095 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic GUU87_RS20105 ENOG4105D4X repressor GUU87_RS20110 ENOG4105C5Y PTS System GUU87_RS20115 ENOG4105CG3 alpha amylase, catalytic region GUU87_RS20120 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase GUU87_RS20125 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) GUU87_RS20130 ENOG4108XVM Cytochrome b(562) GUU87_RS20135 ENOG4105CMS peptidase U62, modulator of DNA gyrase GUU87_RS20145 ENOG4105DFU Cell wall formation (By similarity) GUU87_RS20155 ENOG41062B0 ABC transporter, permease GUU87_RS20160 ENOG4107R9N ABC transporter GUU87_RS20165 ENOG4105C2J ABC transporter GUU87_RS20170 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator GUU87_RS20175 ENOG4105F0N pyrophosphate phospho-hydrolase GUU87_RS20180 ENOG4105MZG transcriptional modulator of maze toxin, mazf GUU87_RS20185 ENOG41087RY SpoVT_AbrB GUU87_RS20190 ENOG4108ZHD aig2 family GUU87_RS20195 ENOG4105MA0 exported protein GUU87_RS20200 ENOG4105CFU surface antigen GUU87_RS20210 ENOG4105C37 (CBS) domain GUU87_RS20215 ENOG41061GZ Protein of unknown function (DUF1107) GUU87_RS20220 ENOG4108UUE Transcriptional regulator GUU87_RS20225 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase GUU87_RS20230 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic GUU87_RS20235 ENOG4105KVH Transcriptional regulator GUU87_RS20240 ENOG4105ECR NmrA family GUU87_RS20245 ENOG4105DXC membrane GUU87_RS20255 ENOG4105C85 amino acid GUU87_RS20260 ENOG4108V1T peptidylprolyl cis-trans isomerase GUU87_RS20265 ENOG4105FHY Opacity-associated protein A GUU87_RS20275 ENOG4105CHR reductase GUU87_RS20285 ENOG4105E39 Enoyl-CoA hydratase GUU87_RS20290 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) GUU87_RS20295 ENOG4107S3R L-aspartate oxidase GUU87_RS20300 ENOG41069H7 transport system small permease component GUU87_RS20305 ENOG4105CG6 trap dicarboxylate transporter dctm subunit GUU87_RS20310 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit GUU87_RS20320 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) GUU87_RS20335 ENOG4105KIT UPF0379 protein yjfY GUU87_RS20355 ENOG4106ETB IIa component GUU87_RS20360 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport GUU87_RS20365 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC GUU87_RS20380 ENOG4108MXZ Esterase GUU87_RS20385 ENOG4105WSB biofilm stress and motility protein A GUU87_RS20390 ENOG4105S17 UPF0379 protein yjfN GUU87_RS20395 ENOG4105CSU acyl-Coa dehydrogenase GUU87_RS20400 ENOG4106032 Glutathionylspermidine synthase GUU87_RS20405 ENOG4108KXT Conserved Protein GUU87_RS20410 ENOG4105Z6B inner membrane protein yjfl GUU87_RS20415 ENOG4107VNS Protein of unknown function (DUF2491) GUU87_RS20420 ENOG4108P9J Phage shock protein A GUU87_RS20425 ENOG4105FUX Conserved Protein GUU87_RS20430 ENOG4105C2N RNA methyltransferase TrmH family group 3 GUU87_RS20435 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) GUU87_RS20455 ENOG4105EPW hflc protein GUU87_RS20460 ENOG4107QJR hflk protein GUU87_RS20465 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) GUU87_RS20470 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) GUU87_RS20485 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GUU87_RS20490 ENOG4105K8N protein family UPF0079, ATPase GUU87_RS20495 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) GUU87_RS20500 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) GUU87_RS20540 ENOG4105EGS Mechanosensitive ion channel GUU87_RS20545 ENOG4107SC7 Inner membrane transporter yjeM GUU87_RS20555 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) GUU87_RS20560 ENOG4105E33 succinate dehydrogenase GUU87_RS20575 ENOG41066YJ Beta-lactamase GUU87_RS20580 ENOG4105QNF Outer membrane lipoprotein GUU87_RS20585 ENOG4105KPY Small multidrug resistance protein GUU87_RS20590 ENOG4106BSU Entericidin B GUU87_RS20595 ENOG4106HKS Entericidin EcnA/B family GUU87_RS20605 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein GUU87_RS20610 ENOG4105MTB Uncharacterized protein YjeJ GUU87_RS20615 ENOG4108ZVF (LipO)protein GUU87_RS20630 ENOG4105DVH amino acid GUU87_RS20635 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 GUU87_RS20640 ENOG4108IJ0 Aspartate ammonia-lyase GUU87_RS20645 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GUU87_RS20660 ENOG4108SIC Transcriptional regulator GUU87_RS20670 ENOG4108M3R transcriptional activator CadC GUU87_RS20675 ENOG4105D5Q Arginine ornithine antiporter GUU87_RS20680 ENOG4105CXN decarboxylase GUU87_RS20685 ENOG4105DUX Transporter GUU87_RS20690 ENOG4105CRK lysyL-tRNA synthetase GUU87_RS20705 ENOG410830R acetyltransferase GUU87_RS20710 ENOG4105VR1 Pfam:DUF1271 GUU87_RS20715 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism GUU87_RS20720 ENOG4108MRH transcriptional regulatory protein GUU87_RS20725 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GUU87_RS20730 ENOG4107GFK fumarate GUU87_RS20735 ENOG4108R5S membrane GUU87_RS20740 ENOG4105CT4 transporter GUU87_RS20745 ENOG4105F8D glycoside hydrolase family 4 GUU87_RS20750 ENOG4108K2B transcriptional regulator GUU87_RS20755 ENOG4105CXN decarboxylase GUU87_RS20760 ENOG4106ZGR Transcriptional regulator GUU87_RS20765 ENOG4105D5Q Arginine ornithine antiporter GUU87_RS20770 ENOG4105DIJ Phosphoethanolamine transferase GUU87_RS20775 ENOG4105XJC Two component transcriptional regulator (Winged helix family GUU87_RS20780 ENOG4105ECM Sensor protein basS pmrB GUU87_RS20790 ENOG4105CSH Transporter GUU87_RS20795 ENOG4108YIV GUU87_RS20800 ENOG4108F5E vimentin GUU87_RS20805 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA GUU87_RS20810 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase GUU87_RS20815 ENOG4105D5T phosphonate abc transporter GUU87_RS20820 ENOG4105EHI Phosphonate ABC transporter, periplasmic GUU87_RS20830 ENOG4107RJJ Transcriptional regulator GUU87_RS20835 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG GUU87_RS20840 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH GUU87_RS20845 ENOG4105EKV Phosphonate metabolism protein GUU87_RS20850 ENOG4105FT8 Phosphonate metabolism GUU87_RS20855 ENOG4105ENV phosphonate C-P lyase system protein PhnK GUU87_RS20860 ENOG4105HRV phosphonate c-p lyase system protein phnl GUU87_RS20865 ENOG4105FD8 phosphonate metabolism protein PhnM GUU87_RS20870 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) GUU87_RS20875 ENOG410849A acetyltransferase, (GNAT) family GUU87_RS20880 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein GUU87_RS20885 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 GUU87_RS20890 ENOG4108YZG isomerase GUU87_RS20895 ENOG4105EUZ Beta-lactamase domain protein GUU87_RS20900 ENOG4106833 GUU87_RS20905 ENOG4105J12 Multidrug resistance protein mdtN GUU87_RS20910 ENOG4108MI0 Resistance protein GUU87_RS20915 ENOG4105ETP RND efflux system, outer membrane lipoprotein GUU87_RS20925 ENOG41082ND Uncharacterized protein yjcO GUU87_RS20930 ENOG4105CK2 sodium dicarboxylate symporter GUU87_RS20935 ENOG4108W0S formate-dependent nitrite reductase complex GUU87_RS20945 ENOG4108QKW cytochrome c-type biogenesis protein GUU87_RS20950 ENOG4105DVI reductase, NrfD GUU87_RS20955 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GUU87_RS20960 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit GUU87_RS20970 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GUU87_RS20975 ENOG41062QD Membrane GUU87_RS20990 ENOG4105EEQ Na H antiporter GUU87_RS20995 ENOG4105C7N Xanthine uracil vitamin C permease GUU87_RS21000 ENOG4108Z4X TRANSCRIPTIONal GUU87_RS21005 ENOG4108W3Q Transcriptional regulator GUU87_RS21010 ENOG4108M8H domain protein GUU87_RS21015 ENOG4105PMV Membrane GUU87_RS21020 ENOG4108UUM single-stranded DNA-binding protein GUU87_RS21025 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) GUU87_RS21030 ENOG4105MSB protein, conserved in bacteria GUU87_RS21035 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme GUU87_RS21040 ENOG4105F0S class B acid phosphatase GUU87_RS21055 ENOG4105CGF Aromatic amino acid aminotransferase GUU87_RS21060 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GUU87_RS21065 ENOG4105CDU Replicative dna helicase GUU87_RS21070 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein GUU87_RS21075 ENOG4105P4Z Phage shock protein G GUU87_RS21080 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GUU87_RS21095 ENOG4105MYN Zinc uptake regulation protein GUU87_RS21100 ENOG4105VDW Csbd family GUU87_RS21105 ENOG4107R73 Mate efflux family protein GUU87_RS21115 ENOG41080IJ Diacylglycerol kinase GUU87_RS21140 ENOG4107W52 maltose operon periplasmic protein GUU87_RS21150 ENOG4108IJ9 (ABC) transporter GUU87_RS21155 ENOG4107FKK extracellular solute-binding protein family 1 GUU87_RS21160 ENOG4105D56 permease protein GUU87_RS21165 ENOG4105EG2 ABC transporter, permease GUU87_RS21170 ENOG4107QNK )-transporter GUU87_RS21185 ENOG4105E3R (LipO)protein GUU87_RS21190 ENOG4108Q9C Periplasmic Protein GUU87_RS21195 ENOG4108MDC (LipO)protein GUU87_RS21210 ENOG4105CFH Aspartokinase GUU87_RS21215 ENOG4108WZA zeta toxin GUU87_RS21220 ENOG410756H nucleotidyltransferase GUU87_RS21230 ENOG4108ZR5 Conserved Protein GUU87_RS21235 ENOG4105FE9 pseudouridine synthase GUU87_RS21245 ENOG4105EAM Na Pi-cotransporter GUU87_RS21250 ENOG4105C3R Methionine synthase GUU87_RS21255 ENOG41069M3 Transcriptional regulator GUU87_RS21270 ENOG4108I9X Isocitrate lyase GUU87_RS21275 ENOG4107QP3 malate synthase g GUU87_RS21285 ENOG4105K5X acetyltransferase GUU87_RS21315 ENOG4105C12 Phosphoribosylglycinamide synthetase GUU87_RS21320 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GUU87_RS21325 ENOG4105BZU Histidine kinase GUU87_RS21330 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism GUU87_RS21335 ENOG4108T8B Protein of unknown function (DUF1481) GUU87_RS21340 ENOG4105K70 DNA-binding protein GUU87_RS21345 ENOG4105R2J Conserved Protein GUU87_RS21380 ENOG4105D06 uba thif-type nad fad binding protein GUU87_RS21385 ENOG4105WHD thiamine biosynthesis protein ThiS GUU87_RS21395 ENOG4105D41 biosynthesis protein thiH GUU87_RS21435 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) GUU87_RS21440 ENOG4105PM1 preprotein translocase subunit SecE GUU87_RS21475 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase GUU87_RS21480 ENOG4105D4A Cell wall formation (By similarity) GUU87_RS21520 ENOG4108Y73 Membrane GUU87_RS21525 ENOG4105EJ2 Transcriptional regulator GUU87_RS21535 ENOG4105C5Q Transcriptional regulator GUU87_RS21540 ENOG4108I5G Major Facilitator superfamily GUU87_RS21545 ENOG4105CXK mandelate racemase muconate lactonizing GUU87_RS21555 ENOG4105CAS nag kinase GUU87_RS21560 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase GUU87_RS21575 ENOG4105DIJ Phosphoethanolamine transferase GUU87_RS21580 ENOG4106R3P AraC family transcriptional regulator GUU87_RS21585 ENOG4108XCZ PTS System GUU87_RS21590 ENOG4108AHH pyruvate formate lyase II activase GUU87_RS21595 ENOG4105C6N Formate acetyltransferase GUU87_RS21600 ENOG4108YRF PTS System GUU87_RS21605 ENOG4105DM4 PTS System GUU87_RS21610 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GUU87_RS21615 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GUU87_RS21620 ENOG4105DCT glycerol dehydrogenase GUU87_RS21625 ENOG4108XC3 NADH ubiquinone oxidoreductase GUU87_RS21630 ENOG4108Q5Y Membrane GUU87_RS21635 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) GUU87_RS21640 ENOG4105SYT Methylenetetrahydrofolate reductase GUU87_RS21645 ENOG4105CFH Aspartokinase GUU87_RS21650 ENOG4105C28 cystathionine GUU87_RS21660 ENOG4107S01 Repressor protein MetJ GUU87_RS21670 ENOG4105CNA YD repeat protein GUU87_RS21680 ENOG4105C25 Primosomal protein n' GUU87_RS21685 ENOG4105ETE Transcriptional regulator (LacI family GUU87_RS21690 ENOG41063M6 Cell Division Protein GUU87_RS21705 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase GUU87_RS21720 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) GUU87_RS21730 ENOG4105CBT Fructose-1,6-bisphosphatase GUU87_RS21735 ENOG4105DP0 ferredoxin-NADP reductase GUU87_RS21745 ENOG41065TG regulatoR GUU87_RS21750 ENOG4108VTS Membrane GUU87_RS21755 ENOG4105EBK exported protein GUU87_RS21770 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein GUU87_RS21785 ENOG4105FMW periplasmic GUU87_RS21790 ENOG4105E3W Two component transcriptional regulator (Winged helix family GUU87_RS21795 ENOG4105E0F Histidine kinase GUU87_RS21800 ENOG4108RPX mosc domain containing protein GUU87_RS21810 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GUU87_RS21850 ENOG41064BA PTS system, fructose-specific, IIA component GUU87_RS21855 ENOG4105DM4 PTS System GUU87_RS21860 ENOG4105CN9 Peptidase m42 family protein GUU87_RS21865 ENOG4106C3V frv operon regulatory protein GUU87_RS21870 ENOG4108V87 frv operon regulatory protein GUU87_RS21885 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GUU87_RS21890 ENOG4108MG3 formate dehydrogenase GUU87_RS21900 ENOG41068KX affects formate dehydrogenase-N GUU87_RS21905 ENOG4106UEE Transcriptional regulator GUU87_RS21915 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system GUU87_RS21925 ENOG4105SUU thioesterase domain GUU87_RS21940 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 GUU87_RS21945 ENOG4105E98 transcriptional regulator DeoR family GUU87_RS21950 ENOG4108MGF sugar kinase GUU87_RS21955 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GUU87_RS21960 ENOG4105D2M Aldolase GUU87_RS21965 ENOG4107QKS N-acylglucosamine 2-epimerase GUU87_RS21970 ENOG4107WI4 Aldose-1-epimerase GUU87_RS21975 ENOG4105CJQ hydrolase, family 31 GUU87_RS21980 ENOG4105CT4 transporter GUU87_RS21985 ENOG4105CT4 transporter GUU87_RS21990 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is GUU87_RS21995 ENOG4105R9B Major Facilitator GUU87_RS22000 ENOG4108KHF Resistance protein GUU87_RS22005 ENOG4108K85 Transcriptional regulator GUU87_RS22015 ENOG4105C5F glutamine synthetase GUU87_RS22020 ENOG4105CUX Signal transduction histidine kinase GUU87_RS22025 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GUU87_RS22030 ENOG4106FIY GUU87_RS22035 ENOG4105D4P Coproporphyrinogen iii oxidase GUU87_RS22050 ENOG4105C2M dna polymerase I GUU87_RS22060 ENOG4106HNH Acyl-transferase GUU87_RS22070 ENOG4108Z33 Thiol disulfide Interchange Protein GUU87_RS22075 ENOG4105E27 serine threonine protein kinase GUU87_RS22080 ENOG4105PC1 Conserved Protein GUU87_RS22085 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) GUU87_RS22090 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b GUU87_RS22120 ENOG4108RR8 protoporphyrinogen oxidase GUU87_RS22125 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) GUU87_RS22130 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein GUU87_RS22150 ENOG4107QK7 reductase GUU87_RS22155 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) GUU87_RS22160 ENOG4105MDZ Transcriptional activator rfaH GUU87_RS22170 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) GUU87_RS22175 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) GUU87_RS22180 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) GUU87_RS22190 ENOG4105JC1 sterol-binding domain protein GUU87_RS22200 ENOG4105CGY Dna recombination protein GUU87_RS22205 ENOG4108I5U Uridine phosphorylase GUU87_RS22210 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) GUU87_RS22220 ENOG4105DZ2 Transcriptional regulator GUU87_RS22225 ENOG4105EMK carboxylate amino acid amine transporter GUU87_RS22230 ENOG4105DQF Hydrolase GUU87_RS22235 ENOG4108EUD Lysophospholipase GUU87_RS22250 ENOG4105C9U ATP-dependent DNA helicase RecQ GUU87_RS22255 ENOG4105HDD phospholipase GUU87_RS22260 ENOG4108VUY thioesterase Superfamily protein GUU87_RS22265 ENOG4105FR1 rard protein GUU87_RS22275 ENOG4107QUT magnesium and cobalt transport protein CorA GUU87_RS22290 ENOG4107QUT magnesium and cobalt transport protein CorA GUU87_RS22295 ENOG4108T58 Mg2 transport protein CorA GUU87_RS22300 ENOG4105C4R Atp-dependent dna helicase GUU87_RS22305 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant GUU87_RS22315 ENOG4105CT0 Protein of unknown function, DUF484 GUU87_RS22325 ENOG4105S7Z (LipO)protein GUU87_RS22350 ENOG4107T0K Adenylate cyclase GUU87_RS22360 ENOG41076E6 Uroporphyrinogen-III Synthase GUU87_RS22365 ENOG4105ECF c-methyltransferase GUU87_RS22370 ENOG410601J HemY protein GUU87_RS22375 ENOG4105C4X radical SAM domain protein GUU87_RS22400 ENOG4105C85 amino acid GUU87_RS22420 ENOG4105EGZ biosynthesis protein GUU87_RS22425 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase GUU87_RS22430 ENOG4108WJ1 acetyltransferase GUU87_RS22435 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) GUU87_RS22440 ENOG4105C1B dTDP-glucose 4-6-dehydratase GUU87_RS22445 ENOG4108IJ1 Dehydrogenase GUU87_RS22450 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase GUU87_RS22455 ENOG4105SFE lipopolysaccharide biosynthesis protein GUU87_RS22460 ENOG4105ESV Glycosyl transferase, family 4 GUU87_RS22475 ENOG4105K63 Thioredoxin GUU87_RS22490 ENOG4105C4R Atp-dependent dna helicase GUU87_RS22500 ENOG4105KQ5 peptidylprolyl cis-trans isomerase GUU87_RS22510 ENOG4105EMY transcriptional regulator GUU87_RS22520 ENOG4105C7B Threonine dehydratase GUU87_RS22530 ENOG4105CM2 brancheD-chain amino acid aminotransferase GUU87_RS22535 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit GUU87_RS22555 ENOG4105C0P Mg chelatase subunit ChlI GUU87_RS22560 ENOG4108WFC UPF0438 protein yifE GUU87_RS22600 ENOG4107EJG GntR family transcriptional regulator GUU87_RS22605 ENOG4105C0R drug resistance transporter emrb qaca subfamily GUU87_RS22610 ENOG4105ETE Transcriptional regulator (LacI family GUU87_RS22615 ENOG4108RVA ribokinase GUU87_RS22620 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator GUU87_RS22625 ENOG4105CNN ABC, transporter GUU87_RS22630 ENOG4105C2J ABC transporter GUU87_RS22660 ENOG4108VVK transcriptional Regulator, AsnC GUU87_RS22665 ENOG4105QTB Flavodoxin GUU87_RS22680 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation GUU87_RS22690 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) GUU87_RS22730 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) GUU87_RS22745 ENOG4105CW0 outer membrane usher protein GUU87_RS22755 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) GUU87_RS22760 ENOG4105C8U phosphate abc transporter GUU87_RS22765 ENOG4105E2Z phosphate ABC transporter (Permease GUU87_RS22770 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GUU87_RS22775 ENOG4108UTW Plays a role in the regulation of phosphate uptake GUU87_RS22780 ENOG4105CID antiterminator GUU87_RS22785 ENOG4105C5Y PTS System GUU87_RS22790 ENOG4105CS2 ec 3.2.1.21 GUU87_RS22800 ENOG4105DYC esterase GUU87_RS22805 ENOG4107VKM 6-phosphogluconolactonase GUU87_RS22810 ENOG4106611 bacteriocin immunity GUU87_RS22820 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 GUU87_RS22825 ENOG4105C7N Xanthine uracil vitamin C permease GUU87_RS22830 ENOG4108YYH Nadph-dependent fmn reductase GUU87_RS22835 ENOG4105E8Q phosphopantetheinyl transferase GUU87_RS22850 ENOG4108P6C Tryptophan transporter of low affinity GUU87_RS22895 ENOG4106JVB Replication Protein GUU87_RS23035 ENOG4105C4R Atp-dependent dna helicase GUU87_RS23145 ENOG4105F9F transposase GUU87_RS23190 ENOG4108M24 von Willebrand factor, type A GUU87_RS23195 ENOG4108M24 von Willebrand factor, type A GUU87_RS23225 ENOG4105DAX Pfam:DUF2983 GUU87_RS23305 ENOG4105CAF HipA N-terminal domain protein GUU87_RS23410 ENOG4105EQR Transposase IS116 IS110 IS902 GUU87_RS23560 ENOG4105EUV Phenol 2-monooxygenase GUU87_RS23580 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) GUU87_RS23625 ENOG4105EQR Transposase IS116 IS110 IS902 GUU87_RS23695 ENOG4105EMU Dehydrogenase GUU87_RS23730 ENOG4108JCI Transcriptional regulator GUU87_RS23775 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) GUU87_RS23795 ENOG4105T95 Thiol disulfide interChange protein GUU87_RS23950 ENOG41074AV Hok/gef family GUU87_RS24115 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) GUU87_RS24135 ENOG4106JVB Replication Protein GUU87_RS24175 ENOG4105DFE Dna adenine methylase GUU87_RS24200 ENOG4106JVB Replication Protein GUU87_RS24225 ENOG4108NC2 Outer membrane protease GUU87_RS24250 ENOG4105DJY efflux transporter, rnd family, mfp subunit GUU87_RS24260 ENOG4105ENJ RND efflux system, outer membrane lipoprotein GUU87_RS24295 ENOG4105QYK bacteriophage lambda Bor protein homolog GUU87_RS24320 ENOG4105E93 esterase GUU87_RS24325 ENOG4105NIV Esterase GUU87_RS24330 ENOG4107RNH Outer membrane receptor FepA GUU87_RS24390 ENOG4105DB4 GUU87_RS24565 ENOG4106CQM replication GUU87_RS24585 ENOG4105KF5 hemolysin expression-modulating protein GUU87_RS24590 ENOG4105KK6 nuclease GUU87_RS24805 ENOG41074AV Hok/gef family GUU87_RS24825 ENOG4105FEQ ParB domain protein nuclease GUU87_RS24915 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB GUU87_RS24920 ENOG4105EZN Cobyrinic acid ac-diamide synthase