locus-tag	class	description
C2H82_RS00010	COG0527	aspartate kinase activity
C2H82_RS00010	COG0460	homoserine dehydrogenase
C2H82_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C2H82_RS00035	COG1115	amino acid carrier protein
C2H82_RS00040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C2H82_RS00045	COG0521	Mo-molybdopterin cofactor biosynthetic process
C2H82_RS00050	COG1584	GPR1 FUN34 yaaH family protein
C2H82_RS00055	COG4735	regulation of single-species biofilm formation
C2H82_RS00075	COG3385	transposase activity
C2H82_RS00085	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C2H82_RS00090	COG0583	DNA-binding transcription factor activity
C2H82_RS00115	COG0196	riboflavin kinase activity
C2H82_RS00130	COG1047	Peptidyl-prolyl cis-trans
C2H82_RS00150	COG0505	Belongs to the CarA family
C2H82_RS00155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C2H82_RS00210	COG0644	oxidoreductase
C2H82_RS00215	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C2H82_RS00220	COG2271	Major facilitator Superfamily
C2H82_RS00235	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C2H82_RS00260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2H82_RS00265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C2H82_RS00270	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C2H82_RS00275	COG1357	PFAM Pentapeptide repeats (8 copies)
C2H82_RS00285	COG0564	pseudouridine synthase activity
C2H82_RS00295	COG0417	DNA replication proofreading
C2H82_RS00300	COG0235	Class ii aldolase
C2H82_RS00305	COG2160	L-arabinose isomerase activity
C2H82_RS00310	COG1069	ribulokinase activity
C2H82_RS00320	COG4977	sequence-specific DNA binding
C2H82_RS00325	COG0586	Pfam SNARE associated Golgi protein
C2H82_RS00330	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C2H82_RS00335	COG1178	ABC-type Fe3 transport system permease component
C2H82_RS00340	COG4143	(ABC) transporter
C2H82_RS00345	COG4533	DNA binding
C2H82_RS00355	COG2814	Major facilitator Superfamily
C2H82_RS00370	COG0473	3-isopropylmalate dehydrogenase activity
C2H82_RS00385	COG0583	DNA-binding transcription factor activity
C2H82_RS00390	COG0028	Belongs to the TPP enzyme family
C2H82_RS00395	COG0440	acetolactate synthase activity
C2H82_RS00405	COG1609	Transcriptional regulator
C2H82_RS00415	COG2001	Belongs to the MraZ family
C2H82_RS00425	COG3116	cell division
C2H82_RS00430	COG0768	penicillin binding
C2H82_RS00435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C2H82_RS00440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C2H82_RS00450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C2H82_RS00455	COG0772	Belongs to the SEDS family
C2H82_RS00470	COG1181	Belongs to the D-alanine--D-alanine ligase family
C2H82_RS00475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C2H82_RS00480	COG0849	cell division
C2H82_RS00485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C2H82_RS00505	COG0494	nUDIX hydrolase
C2H82_RS00520	COG0237	dephospho-CoA kinase activity
C2H82_RS00530	COG1459	type II secretion system
C2H82_RS00535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C2H82_RS00540	COG4969	Belongs to the N-Me-Phe pilin family
C2H82_RS00550	COG0157	Belongs to the NadC ModD family
C2H82_RS00555	COG3023	N-Acetylmuramoyl-L-alanine amidase
C2H82_RS00560	COG3725	Membrane protein required for beta-lactamase induction
C2H82_RS00565	COG1113	amino acid transport
C2H82_RS00570	COG2186	Transcriptional regulator
C2H82_RS00580	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C2H82_RS00585	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2H82_RS00590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2H82_RS00595	COG3064	Membrane
C2H82_RS00605	COG1049	propionate catabolic process, 2-methylcitrate cycle
C2H82_RS00630	COG2132	Multicopper oxidase
C2H82_RS00635	COG4993	Dehydrogenase
C2H82_RS00640	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C2H82_RS00645	COG0288	reversible hydration of carbon dioxide
C2H82_RS00650	COG1131	(ABC) transporter
C2H82_RS00655	COG0842	Transport permease protein
C2H82_RS00660	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS00665	COG0726	polysaccharide deacetylase
C2H82_RS00685	COG5464	transposase or invertase
C2H82_RS00700	COG3539	Fimbrial protein
C2H82_RS00705	COG3539	Fimbrial protein
C2H82_RS00710	COG3539	Fimbrial protein
C2H82_RS00715	COG3539	Fimbrial protein
C2H82_RS00720	COG3188	usher protein
C2H82_RS00725	COG3121	Chaperone
C2H82_RS00730	COG3539	Fimbrial protein
C2H82_RS00735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2H82_RS00740	COG0617	tRNA 3'-terminal CCA addition
C2H82_RS00750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2H82_RS00760	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C2H82_RS00765	COG1643	Atp-dependent helicase
C2H82_RS00775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2H82_RS00780	COG4774	siderophore transport
C2H82_RS00785	COG1120	ATPase activity
C2H82_RS00790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2H82_RS00795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H82_RS00815	COG2860	membrane
C2H82_RS00820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2H82_RS00840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2H82_RS00845	COG3835	regulator
C2H82_RS00855	COG1408	metallophosphoesterase
C2H82_RS00870	COG0024	Methionine aminopeptidase
C2H82_RS00905	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C2H82_RS00910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C2H82_RS00915	COG0575	Belongs to the CDS family
C2H82_RS00920	COG0750	zinc metalloprotease
C2H82_RS00930	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C2H82_RS00935	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C2H82_RS00960	COG0587	DNA-directed DNA polymerase activity
C2H82_RS00970	COG1982	Orn Lys Arg decarboxylase major
C2H82_RS00975	COG0346	lactoylglutathione lyase activity
C2H82_RS00980	COG0037	tRNA processing
C2H82_RS00985	COG4568	rho-dependent transcription termination
C2H82_RS00995	COG4681	YaeQ
C2H82_RS01000	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C2H82_RS01005	COG3015	lipoprotein NlpE involved in copper resistance
C2H82_RS01010	COG0791	NLP P60 protein
C2H82_RS01020	COG1720	tRNA m6t6A37 methyltransferase activity
C2H82_RS01030	COG1464	Belongs to the NlpA lipoprotein family
C2H82_RS01035	COG2011	ABC-type metal ion transport system permease component
C2H82_RS01040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C2H82_RS01045	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C2H82_RS01080	COG0656	L-ascorbic acid biosynthetic process
C2H82_RS01085	COG0583	DNA-binding transcription factor activity
C2H82_RS01095	COG2226	methyltransferase
C2H82_RS01100	COG0741	lytic transglycosylase activity
C2H82_RS01100	COG1388	LysM domain
C2H82_RS01110	COG2226	methyltransferase
C2H82_RS01120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2H82_RS01155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2H82_RS01165	COG1960	acyl-CoA dehydrogenase activity
C2H82_RS01175	COG0121	glutamine amidotransferase
C2H82_RS01180	COG3034	peptidoglycan biosynthetic process
C2H82_RS01185	COG3041	Addiction module toxin RelE StbE family
C2H82_RS01190	COG3077	Addiction module antitoxin, RelB DinJ family
C2H82_RS01195	COG0791	NLP P60 protein
C2H82_RS01200	COG1943	Transposase
C2H82_RS01220	COG2161	toxin-antitoxin pair type II binding
C2H82_RS01230	COG0454	-acetyltransferase
C2H82_RS01235	COG1690	Belongs to the RtcB family
C2H82_RS01240	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C2H82_RS01245	COG2195	Cleaves the N-terminal amino acid of tripeptides
C2H82_RS01265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C2H82_RS01300	COG2003	Belongs to the UPF0758 family
C2H82_RS01320	COG2378	regulation of single-species biofilm formation
C2H82_RS01340	COG3596	GTP binding
C2H82_RS01345	COG0583	DNA-binding transcription factor activity
C2H82_RS01355	COG2963	transposase activity
C2H82_RS01360	COG2826	transposase and inactivated derivatives, IS30 family
C2H82_RS01390	COG0833	amino acid
C2H82_RS01395	COG2040	homocysteine
C2H82_RS01400	COG3842	ATPase activity
C2H82_RS01435	COG3415	Transposase
C2H82_RS01435	COG2801	Transposase and inactivated derivatives
C2H82_RS01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2H82_RS01445	COG0129	dihydroxy-acid dehydratase activity
C2H82_RS01450	COG2211	Major facilitator Superfamily
C2H82_RS01455	COG3507	Belongs to the glycosyl hydrolase 43 family
C2H82_RS01460	COG1414	Transcriptional regulator
C2H82_RS01465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C2H82_RS01490	COG1061	Type III restriction enzyme res subunit
C2H82_RS01500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2H82_RS01520	COG0582	viral genome integration into host DNA
C2H82_RS01530	COG0583	DNA-binding transcription factor activity
C2H82_RS01535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C2H82_RS01540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C2H82_RS01545	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C2H82_RS01550	COG2080	2 iron, 2 sulfur cluster binding
C2H82_RS01560	COG3477	response to acidic pH
C2H82_RS01570	COG0727	PFAM Uncharacterised protein family (UPF0153)
C2H82_RS01575	COG3121	Chaperone
C2H82_RS01585	COG3188	usher protein
C2H82_RS01640	COG1388	LysM domain
C2H82_RS01655	COG3059	membrane
C2H82_RS01665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2H82_RS01670	COG2207	Transcriptional regulator
C2H82_RS01675	COG0247	lactate metabolic process
C2H82_RS01680	COG1139	Iron-sulfur cluster binding protein
C2H82_RS01685	COG1556	Lactate utilization protein
C2H82_RS01725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C2H82_RS01740	COG2771	luxR family
C2H82_RS01740	COG2200	EAL domain
C2H82_RS01745	COG0583	DNA-binding transcription factor activity
C2H82_RS01760	COG0666	response to abiotic stimulus
C2H82_RS01770	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2H82_RS01775	COG1304	FMN binding
C2H82_RS01785	COG0549	Belongs to the carbamate kinase family
C2H82_RS01790	COG0402	S-adenosylhomocysteine deaminase activity
C2H82_RS01795	COG1064	alcohol dehydrogenase
C2H82_RS01810	COG1280	lysine exporter protein (LysE YggA)
C2H82_RS01820	COG3829	transcription factor binding
C2H82_RS01825	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C2H82_RS01830	COG0372	Belongs to the citrate synthase family
C2H82_RS01835	COG2079	MmgE PrpD family protein
C2H82_RS01840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C2H82_RS01845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C2H82_RS01850	COG0402	S-adenosylhomocysteine deaminase activity
C2H82_RS01855	COG0583	DNA-binding transcription factor activity
C2H82_RS01860	COG0288	reversible hydration of carbon dioxide
C2H82_RS01870	COG2807	transmembrane transport
C2H82_RS01875	COG0110	maltose O-acetyltransferase activity
C2H82_RS01880	COG2223	nitrite transmembrane transporter activity
C2H82_RS01885	COG3250	beta-galactosidase activity
C2H82_RS01895	COG1609	Transcriptional regulator
C2H82_RS01900	COG1414	Transcriptional regulator
C2H82_RS01920	COG3971	2-oxopent-4-enoate hydratase activity
C2H82_RS01935	COG2814	Major facilitator Superfamily
C2H82_RS01940	COG3122	Protein conserved in bacteria
C2H82_RS01950	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C2H82_RS01985	COG1215	transferase activity, transferring glycosyl groups
C2H82_RS01990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C2H82_RS02000	COG4521	taurine ABC transporter
C2H82_RS02010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2H82_RS02015	COG2175	clavaminate synthase activity
C2H82_RS02020	COG0113	porphobilinogen synthase activity
C2H82_RS02030	COG3468	outer membrane autotransporter barrel domain protein
C2H82_RS02045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2H82_RS02050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C2H82_RS02060	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C2H82_RS02085	COG1181	Belongs to the D-alanine--D-alanine ligase family
C2H82_RS02100	COG1785	Belongs to the alkaline phosphatase family
C2H82_RS02110	COG3706	GGDEF domain
C2H82_RS02115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C2H82_RS02140	COG4126	flavin adenine dinucleotide binding
C2H82_RS02165	COG1940	carbohydrate kinase activity
C2H82_RS02170	COG2814	Major facilitator Superfamily
C2H82_RS02175	COG0419	ATPase involved in DNA repair
C2H82_RS02180	COG0420	3'-5' exonuclease activity
C2H82_RS02185	COG0745	RESPONSE REGULATOR receiver
C2H82_RS02190	COG5002	protein histidine kinase activity
C2H82_RS02195	COG1114	Component of the transport system for branched-chain amino acids
C2H82_RS02200	COG1113	amino acid transport
C2H82_RS02205	COG0366	Alpha amylase catalytic
C2H82_RS02225	COG1862	Preprotein translocase
C2H82_RS02230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2H82_RS02235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2H82_RS02240	COG1403	HNH endonuclease
C2H82_RS02245	COG3248	Nucleoside-binding outer membrane protein
C2H82_RS02255	COG4238	major outer membrane lipoprotein
C2H82_RS02265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2H82_RS02265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2H82_RS02280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C2H82_RS02285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C2H82_RS02290	COG0667	Aldo Keto reductase
C2H82_RS02300	COG0142	geranyltranstransferase activity
C2H82_RS02315	COG0693	protein deglycase activity
C2H82_RS02320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C2H82_RS02330	COG2814	Major facilitator Superfamily
C2H82_RS02340	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C2H82_RS02345	COG1845	cytochrome c oxidase, subunit III
C2H82_RS02350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C2H82_RS02355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C2H82_RS02360	COG2223	nitrite transmembrane transporter activity
C2H82_RS02365	COG3056	Lipoprotein
C2H82_RS02375	COG0271	Belongs to the BolA IbaG family
C2H82_RS02400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C2H82_RS02405	COG0776	regulation of translation
C2H82_RS02410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2H82_RS02415	COG1555	photosystem II stabilization
C2H82_RS02420	COG0824	Thioesterase
C2H82_RS02430	COG4533	DNA binding
C2H82_RS02440	COG1522	sequence-specific DNA binding
C2H82_RS02445	COG1132	(ABC) transporter
C2H82_RS02450	COG1132	(ABC) transporter
C2H82_RS02455	COG0347	Belongs to the P(II) protein family
C2H82_RS02460	COG0004	ammonium transporteR
C2H82_RS02465	COG1946	Acyl-CoA thioesterase
C2H82_RS02470	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C2H82_RS02475	COG3695	enzyme binding
C2H82_RS02485	COG5507	3-demethylubiquinone-9 3-methyltransferase
C2H82_RS02490	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C2H82_RS02500	COG0110	maltose O-acetyltransferase activity
C2H82_RS02515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2H82_RS02520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2H82_RS02535	COG1196	nuclear chromosome segregation
C2H82_RS02535	COG3264	Mechanosensitive ion channel
C2H82_RS02545	COG3923	Primosomal replication protein n
C2H82_RS02550	COG2832	Protein of unknown function (DUF454)
C2H82_RS02565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C2H82_RS02605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H82_RS02610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C2H82_RS02610	COG4651	solute:proton antiporter activity
C2H82_RS02615	COG2223	nitrite transmembrane transporter activity
C2H82_RS02625	COG0737	Belongs to the 5'-nucleotidase family
C2H82_RS02630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2H82_RS02640	COG3735	TraB family
C2H82_RS02650	COG3093	addiction module antidote protein HigA
C2H82_RS02655	COG2217	Heavy metal translocating P-type atpase
C2H82_RS02660	COG2066	Belongs to the glutaminase family
C2H82_RS02665	COG0531	amino acid
C2H82_RS02670	COG0789	Transcriptional regulator
C2H82_RS02675	COG1585	Membrane protein implicated in regulation of membrane protease activity
C2H82_RS02680	COG0330	HflC and HflK could
C2H82_RS02685	COG4619	ABC transporter
C2H82_RS02690	COG0390	transport system, permease component
C2H82_RS02695	COG3118	belongs to the thioredoxin family
C2H82_RS02700	COG0300	oxidoreductase activity
C2H82_RS02705	COG2755	lipolytic protein G-D-S-L family
C2H82_RS02710	COG4181	ATPase activity
C2H82_RS02715	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C2H82_RS02720	COG3209	COG3209 Rhs family protein
C2H82_RS02755	COG0583	DNA-binding transcription factor activity
C2H82_RS02765	COG1414	Transcriptional regulator
C2H82_RS02770	COG3960	tartronate-semialdehyde synthase activity
C2H82_RS02775	COG3622	Belongs to the hyi family
C2H82_RS02780	COG2084	Dehydrogenase
C2H82_RS02785	COG1953	Uracil, thiamine, allantoin
C2H82_RS02795	COG2233	PERMEase
C2H82_RS02800	COG1929	Belongs to the glycerate kinase type-1 family
C2H82_RS02805	COG3257	ureidoglycine aminohydrolase activity
C2H82_RS02810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2H82_RS02815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C2H82_RS02820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2H82_RS02825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2H82_RS02830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2H82_RS02840	COG0549	Belongs to the carbamate kinase family
C2H82_RS02845	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C2H82_RS02850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C2H82_RS02865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C2H82_RS02875	COG1988	membrane-bound metal-dependent
C2H82_RS02880	COG2501	S4 domain
C2H82_RS02890	COG3539	Fimbrial protein
C2H82_RS02895	COG3121	Chaperone
C2H82_RS02900	COG3188	usher protein
C2H82_RS02905	COG3539	Fimbrial protein
C2H82_RS02910	COG3539	Fimbrial protein
C2H82_RS02915	COG2197	response regulator
C2H82_RS02925	COG0582	viral genome integration into host DNA
C2H82_RS02955	COG2076	Multidrug Resistance protein
C2H82_RS02960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2H82_RS02965	COG1881	PFAM PEBP family protein
C2H82_RS02970	COG2207	Transcriptional regulator
C2H82_RS03035	COG3772	lysozyme
C2H82_RS03050	COG5562	phage envelope protein
C2H82_RS03075	COG4220	transposase activity
C2H82_RS03090	COG0500	methyltransferase
C2H82_RS03100	COG2207	Transcriptional regulator
C2H82_RS03105	COG4571	Outer membrane protease
C2H82_RS03120	COG2207	Transcriptional regulator
C2H82_RS03135	COG4783	chaperone-mediated protein folding
C2H82_RS03140	COG1215	transferase activity, transferring glycosyl groups
C2H82_RS03145	COG5002	protein histidine kinase activity
C2H82_RS03150	COG0745	RESPONSE REGULATOR receiver
C2H82_RS03160	COG1538	Outer membrane efflux protein
C2H82_RS03165	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2H82_RS03170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2H82_RS03175	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2H82_RS03180	COG1113	amino acid transport
C2H82_RS03185	COG0668	transmembrane transport
C2H82_RS03190	COG0778	Nitroreductase
C2H82_RS03195	COG2315	Protein conserved in bacteria
C2H82_RS03225	COG3385	transposase activity
C2H82_RS03230	COG2977	Belongs to the P-Pant transferase superfamily
C2H82_RS03235	COG4771	TonB-dependent receptor
C2H82_RS03240	COG2382	esterase
C2H82_RS03245	COG3251	PFAM MbtH domain protein
C2H82_RS03250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C2H82_RS03250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2H82_RS03255	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C2H82_RS03260	COG1120	ATPase activity
C2H82_RS03265	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H82_RS03270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H82_RS03280	COG4592	Periplasmic binding protein
C2H82_RS03290	COG1169	isochorismate synthase
C2H82_RS03295	COG1021	2,3-dihydroxybenzoate-AMP ligase
C2H82_RS03300	COG3433	isochorismatase activity
C2H82_RS03300	COG1535	isochorismatase
C2H82_RS03305	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS03310	COG2050	protein possibly involved in aromatic compounds catabolism
C2H82_RS03315	COG1966	Carbon starvation protein
C2H82_RS03320	COG2879	small protein
C2H82_RS03325	COG0371	Dehydrogenase
C2H82_RS03330	COG0436	Aminotransferase
C2H82_RS03335	COG1475	DNA binding
C2H82_RS03340	COG3969	phosphoadenosine phosphosulfate
C2H82_RS03345	COG0583	DNA-binding transcription factor activity
C2H82_RS03355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C2H82_RS03360	COG0450	alkyl hydroperoxide reductase
C2H82_RS03365	COG3634	alkyl hydroperoxide reductase activity
C2H82_RS03370	COG0589	response to stress
C2H82_RS03375	COG1063	alcohol dehydrogenase
C2H82_RS03385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C2H82_RS03395	COG3719	Belongs to the RNase T2 family
C2H82_RS03400	COG0471	metal ion transport
C2H82_RS03415	COG3051	citrate lyase alpha subunit
C2H82_RS03420	COG2301	Belongs to the HpcH HpaI aldolase family
C2H82_RS03430	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C2H82_RS03435	COG3290	protein histidine kinase activity
C2H82_RS03440	COG4565	transcriptional regulatory protein
C2H82_RS03445	COG3069	C4-dicarboxylate transmembrane transporter activity
C2H82_RS03475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C2H82_RS03490	COG0583	DNA-binding transcription factor activity
C2H82_RS03510	COG1686	Belongs to the peptidase S11 family
C2H82_RS03515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C2H82_RS03520	COG0772	Belongs to the SEDS family
C2H82_RS03525	COG0768	penicillin binding
C2H82_RS03535	COG0799	negative regulation of ribosome biogenesis
C2H82_RS03540	COG0406	alpha-ribazole phosphatase activity
C2H82_RS03550	COG1466	dna polymerase III delta subunit
C2H82_RS03565	COG2888	peptidyl-tyrosine sulfation
C2H82_RS03570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C2H82_RS03580	COG2214	Heat shock protein DnaJ domain protein
C2H82_RS03585	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C2H82_RS03595	COG2214	Heat shock protein DnaJ domain protein
C2H82_RS03600	COG0443	Heat shock 70 kDa protein
C2H82_RS03610	COG1126	abc transporter atp-binding protein
C2H82_RS03615	COG0765	amino acid transport
C2H82_RS03620	COG0765	amino acid transport
C2H82_RS03625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H82_RS03640	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C2H82_RS03645	COG4535	Mg2 and Co2 transporter CorC
C2H82_RS03655	COG1702	phosphate starvation-inducible protein PhoH
C2H82_RS03665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2H82_RS03710	COG0367	asparagine synthase
C2H82_RS03720	COG0647	UMP catabolic process
C2H82_RS03725	COG1846	Transcriptional regulator
C2H82_RS03725	COG1940	carbohydrate kinase activity
C2H82_RS03730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C2H82_RS03740	COG1263	PTS System
C2H82_RS03740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS03740	COG2190	(PTS) system
C2H82_RS03760	COG0735	belongs to the Fur family
C2H82_RS03770	COG0716	FMN binding
C2H82_RS03780	COG0596	Alpha beta hydrolase
C2H82_RS03785	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C2H82_RS03790	COG0033	Phosphoglucomutase
C2H82_RS03810	COG0531	amino acid
C2H82_RS03815	COG1982	Orn Lys Arg decarboxylase major
C2H82_RS03825	COG0745	RESPONSE REGULATOR receiver
C2H82_RS03830	COG2205	protein histidine kinase activity
C2H82_RS03860	COG3209	COG3209 Rhs family protein
C2H82_RS03895	COG3272	Protein of unknown function (DUF1722)
C2H82_RS03900	COG0415	Belongs to the DNA photolyase family
C2H82_RS03905	COG3104	oligopeptide transport
C2H82_RS03910	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C2H82_RS03915	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C2H82_RS03920	COG1984	allophanate hydrolase subunit 2
C2H82_RS03935	COG3180	Ammonia monooxygenase
C2H82_RS03940	COG3539	Fimbrial protein
C2H82_RS03945	COG3121	Chaperone
C2H82_RS03950	COG3188	usher protein
C2H82_RS03955	COG3539	Fimbrial protein
C2H82_RS03960	COG0372	Belongs to the citrate synthase family
C2H82_RS03975	COG2009	succinate dehydrogenase
C2H82_RS03980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C2H82_RS03985	COG1053	succinate dehydrogenase
C2H82_RS03990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C2H82_RS03995	COG0567	Dehydrogenase, E1 component
C2H82_RS04000	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2H82_RS04010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2H82_RS04015	COG2188	Transcriptional regulator
C2H82_RS04020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS04020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS04020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS04025	COG0383	alpha-mannosidase activity
C2H82_RS04035	COG1271	oxidase subunit
C2H82_RS04040	COG1294	oxidase, subunit
C2H82_RS04045	COG4890	Cyd operon protein YbgT
C2H82_RS04050	COG3790	cyd operon protein YbgE
C2H82_RS04055	COG0824	Thioesterase
C2H82_RS04060	COG0811	peptide transport
C2H82_RS04065	COG0848	biopolymer transport protein
C2H82_RS04070	COG3064	Membrane
C2H82_RS04080	COG2885	chlorophyll binding
C2H82_RS04085	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C2H82_RS04135	COG3201	nicotinamide mononucleotide transporter
C2H82_RS04140	COG1230	cation diffusion facilitator family transporter
C2H82_RS04155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C2H82_RS04165	COG2017	converts alpha-aldose to the beta-anomer
C2H82_RS04175	COG1085	galactose-1-phosphate uridylyltransferase
C2H82_RS04180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C2H82_RS04185	COG1119	ATPase activity
C2H82_RS04190	COG2005	Transcriptional regulator
C2H82_RS04190	COG3585	molybdate ion transport
C2H82_RS04205	COG0725	ABC transporter, periplasmic molybdate-binding protein
C2H82_RS04210	COG4149	molybdate abc transporter
C2H82_RS04215	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C2H82_RS04220	COG0561	phosphatase activity
C2H82_RS04230	COG0583	DNA-binding transcription factor activity
C2H82_RS04235	COG2828	Protein conserved in bacteria
C2H82_RS04240	COG0471	metal ion transport
C2H82_RS04245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C2H82_RS04250	COG4677	pectinesterase activity
C2H82_RS04260	COG1881	PFAM PEBP family protein
C2H82_RS04265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C2H82_RS04280	COG2226	methyltransferase
C2H82_RS04285	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C2H82_RS04295	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C2H82_RS04305	COG0521	Mo-molybdopterin cofactor biosynthetic process
C2H82_RS04315	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C2H82_RS04320	COG0314	molybdopterin synthase activity
C2H82_RS04325	COG0670	Belongs to the BI1 family
C2H82_RS04330	COG0670	Belongs to the BI1 family
C2H82_RS04335	COG0392	lysyltransferase activity
C2H82_RS04340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2H82_RS04345	COG3568	Endonuclease Exonuclease Phosphatase
C2H82_RS04355	COG0842	Transport permease protein
C2H82_RS04360	COG0842	Transport permease protein
C2H82_RS04365	COG1131	(ABC) transporter
C2H82_RS04375	COG1309	transcriptional regulator
C2H82_RS04380	COG0513	Belongs to the DEAD box helicase family
C2H82_RS04385	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C2H82_RS04395	COG1199	ATP-dependent helicase activity
C2H82_RS04400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C2H82_RS04405	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C2H82_RS04415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2H82_RS04425	COG4774	siderophore transport
C2H82_RS04440	COG0668	transmembrane transport
C2H82_RS04445	COG1126	abc transporter atp-binding protein
C2H82_RS04450	COG0765	amino acid transport
C2H82_RS04455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H82_RS04480	COG5006	permease, DMT superfamily
C2H82_RS04485	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C2H82_RS04490	COG2194	sulfuric ester hydrolase activity
C2H82_RS04500	COG1321	iron dependent repressor
C2H82_RS04505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2H82_RS04510	COG1376	ErfK ybiS ycfS ynhG family protein
C2H82_RS04515	COG0488	(ABC) transporter
C2H82_RS04525	COG0561	phosphatase activity
C2H82_RS04530	COG1882	Formate acetyltransferase
C2H82_RS04535	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2H82_RS04540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C2H82_RS04545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2H82_RS04550	COG0303	'Molybdopterin
C2H82_RS04555	COG1446	asparaginase
C2H82_RS04560	COG4172	Belongs to the ABC transporter superfamily
C2H82_RS04565	COG0747	negative chemotaxis
C2H82_RS04575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2H82_RS04580	COG2200	EAL domain
C2H82_RS04585	COG2199	diguanylate cyclase activity
C2H82_RS04600	COG2133	pyrroloquinoline quinone binding
C2H82_RS04605	COG0625	glutathione transferase activity
C2H82_RS04610	COG1686	Belongs to the peptidase S11 family
C2H82_RS04615	COG1349	DNA-binding transcription factor activity
C2H82_RS04620	COG0671	phosphoesterase, PA-phosphatase related
C2H82_RS04625	COG2814	Major facilitator Superfamily
C2H82_RS04635	COG0561	phosphatase activity
C2H82_RS04640	COG0738	Major facilitator superfamily
C2H82_RS04645	COG3226	Transcriptional regulator
C2H82_RS04660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C2H82_RS04670	COG0778	Nitroreductase
C2H82_RS04690	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C2H82_RS04695	COG3842	ATPase activity
C2H82_RS04700	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2H82_RS04705	COG1177	transmembrane transport
C2H82_RS04720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H82_RS04725	COG4160	amino acid transport
C2H82_RS04730	COG4215	(ABC) transporter
C2H82_RS04735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H82_RS04740	COG1126	abc transporter atp-binding protein
C2H82_RS04755	COG3023	N-Acetylmuramoyl-L-alanine amidase
C2H82_RS04760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2H82_RS04765	COG0702	epimerase
C2H82_RS04770	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C2H82_RS04775	COG0028	Belongs to the TPP enzyme family
C2H82_RS04780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2H82_RS04790	COG2431	L-lysine efflux transmembrane transporter activity
C2H82_RS04805	COG3593	DNA synthesis involved in DNA repair
C2H82_RS04810	COG2990	Protein conserved in bacteria
C2H82_RS04815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2H82_RS04820	COG1136	(ABC) transporter
C2H82_RS04820	COG0577	efflux transmembrane transporter activity
C2H82_RS04825	COG1278	Cold shock
C2H82_RS04835	COG0542	response to heat
C2H82_RS04855	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C2H82_RS04860	COG4988	ABC transporter
C2H82_RS04865	COG0492	ferredoxin-NADP+ reductase activity
C2H82_RS04875	COG1522	sequence-specific DNA binding
C2H82_RS04880	COG1178	ABC-type Fe3 transport system permease component
C2H82_RS04880	COG1674	ftsk spoiiie
C2H82_RS04890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C2H82_RS04900	COG0243	molybdopterin cofactor binding
C2H82_RS04905	COG0437	4 iron, 4 sulfur cluster binding
C2H82_RS04910	COG3302	dmso reductase anchor subunit
C2H82_RS04915	COG1335	isochorismatase
C2H82_RS04925	COG0531	amino acid
C2H82_RS04930	COG0583	DNA-binding transcription factor activity
C2H82_RS04935	COG2249	NAD(P)H dehydrogenase (quinone) activity
C2H82_RS04940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2H82_RS04945	COG1882	Formate acetyltransferase
C2H82_RS04950	COG2116	formate transmembrane transporter activity
C2H82_RS04955	COG1944	ATP diphosphatase activity
C2H82_RS04960	COG2323	membrane
C2H82_RS04975	COG0501	Belongs to the peptidase M48B family
C2H82_RS04985	COG0539	negative regulation of cytoplasmic translation
C2H82_RS04995	COG0658	competence protein
C2H82_RS04995	COG2333	competence protein COMEC
C2H82_RS05000	COG1132	(ABC) transporter
C2H82_RS05005	COG1663	tetraacyldisaccharide 4'-kinase activity
C2H82_RS05010	COG3214	Protein conserved in bacteria
C2H82_RS05025	COG3173	Aminoglycoside phosphotransferase
C2H82_RS05030	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C2H82_RS05035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C2H82_RS05045	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C2H82_RS05055	COG2989	Protein conserved in bacteria
C2H82_RS05065	COG3108	Peptidase M15
C2H82_RS05070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2H82_RS05075	COG1448	Aminotransferase
C2H82_RS05095	COG0308	aminopeptidase N
C2H82_RS05100	COG1116	anion transmembrane transporter activity
C2H82_RS05105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2H82_RS05115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2H82_RS05120	COG0431	NADPH-dependent FMN reductase
C2H82_RS05130	COG3539	Fimbrial protein
C2H82_RS05135	COG3121	Chaperone
C2H82_RS05140	COG3188	usher protein
C2H82_RS05145	COG3539	Fimbrial protein
C2H82_RS05150	COG3539	Fimbrial protein
C2H82_RS05155	COG3539	Fimbrial protein
C2H82_RS05160	COG3121	Chaperone
C2H82_RS05175	COG0633	Ferredoxin
C2H82_RS05175	COG3217	Mosc domain protein beta barrel domain protein
C2H82_RS05185	COG0488	(ABC) transporter
C2H82_RS05190	COG2995	paraquat-inducible protein a
C2H82_RS05195	COG3008	intermembrane lipid transfer
C2H82_RS05195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C2H82_RS05200	COG3009	Protein conserved in bacteria
C2H82_RS05205	COG3130	regulation of translation
C2H82_RS05215	COG1067	ATP-dependent peptidase activity
C2H82_RS05225	COG2885	chlorophyll binding
C2H82_RS05225	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C2H82_RS05240	COG3070	regulator of competence-specific genes
C2H82_RS05245	COG1289	transmembrane transporter activity
C2H82_RS05250	COG3304	Inner membrane component domain
C2H82_RS05255	COG0210	DNA helicase
C2H82_RS05270	COG1832	CoA-binding protein
C2H82_RS05285	COG1254	Belongs to the acylphosphatase family
C2H82_RS05290	COG2920	part of a sulfur-relay system
C2H82_RS05295	COG0670	Belongs to the BI1 family
C2H82_RS05305	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C2H82_RS05310	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C2H82_RS05315	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C2H82_RS05320	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C2H82_RS05325	COG1999	signal sequence binding
C2H82_RS05330	COG1773	rubredoxin
C2H82_RS05335	COG1271	oxidase subunit
C2H82_RS05340	COG1294	oxidase, subunit
C2H82_RS05355	COG3206	protein involved in exopolysaccharide biosynthesis
C2H82_RS05355	COG0489	protein tyrosine kinase activity
C2H82_RS05360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C2H82_RS05365	COG1596	polysaccharide export
C2H82_RS05370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2H82_RS05400	COG1278	Cold shock
C2H82_RS05405	COG1278	Cold shock
C2H82_RS05425	COG0348	domain, Protein
C2H82_RS05430	COG2198	Histidine kinase
C2H82_RS05430	COG0784	Response regulator, receiver
C2H82_RS05430	COG2205	protein histidine kinase activity
C2H82_RS05435	COG1879	ABC-type sugar transport system periplasmic component
C2H82_RS05440	COG0745	RESPONSE REGULATOR receiver
C2H82_RS05445	COG3005	denitrification pathway
C2H82_RS05450	COG0243	molybdopterin cofactor binding
C2H82_RS05455	COG3381	protein complex oligomerization
C2H82_RS05495	COG3729	General stress protein
C2H82_RS05500	COG2233	PERMEase
C2H82_RS05535	COG1309	transcriptional regulator
C2H82_RS05540	COG0506	proline dehydrogenase activity
C2H82_RS05540	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C2H82_RS05540	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C2H82_RS05555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2H82_RS05580	COG2822	iron ion transport
C2H82_RS05585	COG2837	iron assimilation
C2H82_RS05590	COG1702	phosphate starvation-inducible protein PhoH
C2H82_RS05595	COG3658	cytochrome
C2H82_RS05600	COG1215	transferase activity, transferring glycosyl groups
C2H82_RS05605	COG0726	polysaccharide deacetylase
C2H82_RS05605	COG1649	PFAM Uncharacterised BCR, COG1649
C2H82_RS05610	COG0457	Tetratricopeptide repeat
C2H82_RS05615	COG3706	GGDEF domain
C2H82_RS05660	COG3381	protein complex oligomerization
C2H82_RS05670	COG1462	curli production assembly transport component CsgG
C2H82_RS05685	COG2197	response regulator
C2H82_RS05720	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C2H82_RS05725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2H82_RS05750	COG2943	transferase activity, transferring hexosyl groups
C2H82_RS05755	COG5645	(Lipo)protein
C2H82_RS05770	COG1560	Kdo2-lipid A biosynthetic process
C2H82_RS05780	COG2353	YceI-like domain
C2H82_RS05785	COG3038	cytochrome b561
C2H82_RS05825	COG2999	glutathione oxidoreductase activity
C2H82_RS05835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H82_RS05845	COG0673	inositol 2-dehydrogenase activity
C2H82_RS05850	COG0728	peptidoglycan biosynthetic process
C2H82_RS05855	COG3418	PFAM FlgN family protein
C2H82_RS05860	COG2747	anti-sigma28 factor FlgM
C2H82_RS05865	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C2H82_RS05870	COG1815	bacterial-type flagellum-dependent cell motility
C2H82_RS05875	COG1558	bacterial-type flagellum-dependent cell motility
C2H82_RS05880	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C2H82_RS05885	COG1749	Flagellar hook protein flgE
C2H82_RS05890	COG4787	bacterial-type flagellum-dependent cell motility
C2H82_RS05895	COG4786	Flagellar basal body rod
C2H82_RS05910	COG3951	Flagellar rod assembly protein muramidase FlgJ
C2H82_RS05910	COG1705	Flagellar rod assembly protein muramidase FlgJ
C2H82_RS05915	COG1256	bacterial-type flagellum assembly
C2H82_RS05920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C2H82_RS05925	COG1530	ribonuclease E activity
C2H82_RS05935	COG0564	pseudouridine synthase activity
C2H82_RS05940	COG0424	maF-like protein
C2H82_RS05945	COG1399	metal-binding, possibly nucleic acid-binding protein
C2H82_RS05965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C2H82_RS05970	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS05980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2H82_RS05985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2H82_RS05990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C2H82_RS06000	COG0470	DNA polymerase III
C2H82_RS06005	COG0084	hydrolase, TatD family'
C2H82_RS06010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS06010	COG1263	PTS System
C2H82_RS06015	COG4773	Receptor
C2H82_RS06020	COG0537	adenosine 5'-monophosphoramidase activity
C2H82_RS06025	COG5633	Lipoprotein
C2H82_RS06030	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C2H82_RS06050	COG1252	NADH dehydrogenase
C2H82_RS06055	COG3134	Outer membrane lipoprotein
C2H82_RS06060	COG1309	transcriptional regulator
C2H82_RS06070	COG1388	LysM domain
C2H82_RS06070	COG1376	ErfK ybiS ycfS ynhG family protein
C2H82_RS06075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C2H82_RS06080	COG4763	Acyl-transferase
C2H82_RS06085	COG4591	ABC-type transport system involved in lipoprotein release permease component
C2H82_RS06090	COG1136	(ABC) transporter
C2H82_RS06095	COG4591	ABC-type transport system involved in lipoprotein release permease component
C2H82_RS06105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C2H82_RS06110	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C2H82_RS06120	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C2H82_RS06125	COG1177	transmembrane transport
C2H82_RS06135	COG3842	ATPase activity
C2H82_RS06150	COG2850	peptidyl-arginine hydroxylation
C2H82_RS06155	COG2205	protein histidine kinase activity
C2H82_RS06160	COG0745	RESPONSE REGULATOR receiver
C2H82_RS06165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C2H82_RS06185	COG1187	pseudouridine synthase activity
C2H82_RS06190	COG0538	isocitrate dehydrogenase activity
C2H82_RS06195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C2H82_RS06210	COG0582	viral genome integration into host DNA
C2H82_RS06240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C2H82_RS06245	COG4197	protein conserved in bacteria, prophage-related
C2H82_RS06260	COG1802	Transcriptional regulator
C2H82_RS06260	COG4626	Terminase
C2H82_RS06270	COG4695	Portal protein
C2H82_RS06275	COG3299	homolog of phage Mu protein gp47
C2H82_RS06280	COG3778	Protein conserved in bacteria
C2H82_RS06295	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C2H82_RS06305	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2H82_RS06310	COG1403	HNH endonuclease
C2H82_RS06315	COG0538	isocitrate dehydrogenase activity
C2H82_RS06325	COG5562	phage envelope protein
C2H82_RS06330	COG0789	Transcriptional regulator
C2H82_RS06335	COG2200	EAL domain
C2H82_RS06360	COG2200	EAL domain
C2H82_RS06420	COG2894	cell division
C2H82_RS06450	COG0179	Fumarylacetoacetate (FAA) hydrolase
C2H82_RS06465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C2H82_RS06470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C2H82_RS06475	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C2H82_RS06490	COG2719	SpoVR family
C2H82_RS06500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C2H82_RS06515	COG1619	proteins homologs of microcin C7 resistance protein MccF
C2H82_RS06530	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C2H82_RS06535	COG2261	transglycosylase associated protein
C2H82_RS06555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2H82_RS06555	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C2H82_RS06555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS06560	COG1461	Dihydroxyacetone kinase
C2H82_RS06565	COG2376	Dihydroxyacetone kinase
C2H82_RS06570	COG3284	Transcriptional regulator
C2H82_RS06575	COG3468	outer membrane autotransporter barrel domain protein
C2H82_RS06590	COG0012	GTP binding
C2H82_RS06605	COG0659	secondary active sulfate transmembrane transporter activity
C2H82_RS06615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C2H82_RS06645	COG2890	protein-(glutamine-N5) methyltransferase activity
C2H82_RS06650	COG3094	Invasion gene expression up-regulator, SirB
C2H82_RS06655	COG2912	Transglutaminase-like superfamily
C2H82_RS06685	COG0387	Pfam Sodium calcium exchanger
C2H82_RS06690	COG4572	Cation transport regulator
C2H82_RS06695	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C2H82_RS06700	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C2H82_RS06705	COG4932	domain protein
C2H82_RS06710	COG2197	response regulator
C2H82_RS06715	COG3850	Histidine kinase
C2H82_RS06725	COG2223	nitrite transmembrane transporter activity
C2H82_RS06730	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C2H82_RS06735	COG1140	nitrate reductase beta subunit
C2H82_RS06740	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C2H82_RS06745	COG2181	nitrate reductase activity
C2H82_RS06780	COG0788	formyltetrahydrofolate deformylase activity
C2H82_RS06790	COG1752	Esterase of the alpha-beta hydrolase superfamily
C2H82_RS06795	COG0745	RESPONSE REGULATOR receiver
C2H82_RS06800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C2H82_RS06810	COG1435	thymidine kinase activity
C2H82_RS06820	COG1454	alcohol dehydrogenase
C2H82_RS06820	COG1012	belongs to the aldehyde dehydrogenase family
C2H82_RS06825	COG2095	MarC family integral membrane protein
C2H82_RS06835	COG4166	transmembrane transport
C2H82_RS06840	COG0601	transmembrane transport
C2H82_RS06845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2H82_RS06850	COG0444	Belongs to the ABC transporter superfamily
C2H82_RS06855	COG4608	Belongs to the ABC transporter superfamily
C2H82_RS06875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C2H82_RS06880	COG2350	Protein conserved in bacteria
C2H82_RS06885	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C2H82_RS06890	COG1607	acyl-coa hydrolase
C2H82_RS06910	COG3047	cAMP biosynthetic process
C2H82_RS06915	COG3685	Protein conserved in bacteria
C2H82_RS06920	COG3685	Protein conserved in bacteria
C2H82_RS06925	COG3729	General stress protein
C2H82_RS06940	COG0135	phosphoribosylanthranilate isomerase activity
C2H82_RS06940	COG0134	indole-3-glycerol-phosphate synthase activity
C2H82_RS06945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C2H82_RS06945	COG0512	Glutamine amidotransferase of anthranilate synthase
C2H82_RS06950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C2H82_RS06960	COG0613	PHP domain protein
C2H82_RS06965	COG0009	L-threonylcarbamoyladenylate synthase
C2H82_RS06970	COG4907	membrane protein (DUF2207)
C2H82_RS06975	COG1187	pseudouridine synthase activity
C2H82_RS06980	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C2H82_RS06985	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS06990	COG0616	signal peptide processing
C2H82_RS07005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C2H82_RS07015	COG0583	DNA-binding transcription factor activity
C2H82_RS07035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C2H82_RS07045	COG0671	phosphoesterase, PA-phosphatase related
C2H82_RS07050	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C2H82_RS07055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C2H82_RS07065	COG0023	Translation Initiation Factor
C2H82_RS07075	COG1349	DNA-binding transcription factor activity
C2H82_RS07085	COG5001	Diguanylate cyclase
C2H82_RS07100	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2H82_RS07100	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2H82_RS07105	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C2H82_RS07110	COG2852	Protein conserved in bacteria
C2H82_RS07115	COG4172	Belongs to the ABC transporter superfamily
C2H82_RS07120	COG4172	Belongs to the ABC transporter superfamily
C2H82_RS07125	COG4171	peptide transport system, permease
C2H82_RS07130	COG4168	peptide transport system, permease
C2H82_RS07135	COG4166	transmembrane transport
C2H82_RS07150	COG0531	amino acid
C2H82_RS07155	COG0174	glutamine synthetase
C2H82_RS07160	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C2H82_RS07165	COG1917	Cupin 2, conserved barrel domain protein
C2H82_RS07165	COG1396	sequence-specific DNA binding
C2H82_RS07175	COG1012	belongs to the aldehyde dehydrogenase family
C2H82_RS07180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2H82_RS07185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C2H82_RS07190	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C2H82_RS07195	COG1842	Phage shock protein A
C2H82_RS07205	COG1983	PspC domain protein
C2H82_RS07215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2H82_RS07220	COG0366	Alpha amylase catalytic
C2H82_RS07225	COG1653	transport
C2H82_RS07230	COG1175	transmembrane transport
C2H82_RS07235	COG0395	ABC-type sugar transport system, permease component
C2H82_RS07240	COG1063	alcohol dehydrogenase
C2H82_RS07245	COG1082	Xylose isomerase domain protein TIM barrel
C2H82_RS07250	COG0673	inositol 2-dehydrogenase activity
C2H82_RS07255	COG1554	hydrolase, family 65, central catalytic
C2H82_RS07260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2H82_RS07275	COG1609	Transcriptional regulator
C2H82_RS07280	COG3106	COG3106 Predicted ATPase
C2H82_RS07290	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C2H82_RS07295	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C2H82_RS07300	COG4948	Mandelate Racemase Muconate Lactonizing
C2H82_RS07305	COG2866	Carboxypeptidase
C2H82_RS07310	COG0702	epimerase
C2H82_RS07315	COG1073	alpha beta
C2H82_RS07320	COG0583	DNA-binding transcription factor activity
C2H82_RS07325	COG4166	transmembrane transport
C2H82_RS07330	COG0668	transmembrane transport
C2H82_RS07340	COG3182	Iron-regulated membrane protein
C2H82_RS07345	COG0589	response to stress
C2H82_RS07350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2H82_RS07355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C2H82_RS07360	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C2H82_RS07370	COG1473	amidohydrolase
C2H82_RS07375	COG1473	amidohydrolase
C2H82_RS07380	COG0583	DNA-binding transcription factor activity
C2H82_RS07390	COG2840	Smr protein MutS2
C2H82_RS07395	COG3706	GGDEF domain
C2H82_RS07410	COG0513	Belongs to the DEAD box helicase family
C2H82_RS07420	COG0582	viral genome integration into host DNA
C2H82_RS07440	COG3723	Recombinational DNA repair protein, rece pathway
C2H82_RS07445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2H82_RS07490	COG4197	protein conserved in bacteria, prophage-related
C2H82_RS07500	COG3756	Protein conserved in bacteria
C2H82_RS07505	COG1484	DNA-dependent DNA replication
C2H82_RS07520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C2H82_RS07530	COG1475	DNA binding
C2H82_RS07560	COG3039	Transposase
C2H82_RS07570	COG5301	cellulose 1,4-beta-cellobiosidase activity
C2H82_RS07575	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C2H82_RS07580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2H82_RS07590	COG0589	response to stress
C2H82_RS07595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C2H82_RS07605	COG0674	pyruvate-flavodoxin oxidoreductase activity
C2H82_RS07605	COG1013	pyruvate-flavodoxin oxidoreductase activity
C2H82_RS07605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C2H82_RS07605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2H82_RS07610	COG3042	response to heat
C2H82_RS07615	COG3187	Heat shock protein
C2H82_RS07620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C2H82_RS07625	COG2911	Protein conserved in bacteria
C2H82_RS07635	COG3784	Protein of unknown function (DUF1318)
C2H82_RS07640	COG2207	Transcriptional regulator
C2H82_RS07645	COG1012	belongs to the aldehyde dehydrogenase family
C2H82_RS07650	COG3733	amine oxidase
C2H82_RS07655	COG2030	dehydratase
C2H82_RS07655	COG1012	belongs to the aldehyde dehydrogenase family
C2H82_RS07660	COG3396	Phenylacetate-CoA oxygenase
C2H82_RS07665	COG3460	Phenylacetate-CoA oxygenase
C2H82_RS07670	COG3396	Phenylacetate-CoA oxygenase
C2H82_RS07675	COG2151	metal-sulfur cluster biosynthetic enzyme
C2H82_RS07680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2H82_RS07685	COG1024	Enoyl-CoA hydratase
C2H82_RS07690	COG1024	Enoyl-CoA hydratase
C2H82_RS07695	COG1250	3-hydroxyacyl-CoA dehydrogenase
C2H82_RS07700	COG2050	protein possibly involved in aromatic compounds catabolism
C2H82_RS07705	COG0183	Belongs to the thiolase family
C2H82_RS07710	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C2H82_RS07715	COG3327	negative regulation of DNA-templated transcription, initiation
C2H82_RS07720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C2H82_RS07740	COG2826	transposase and inactivated derivatives, IS30 family
C2H82_RS07755	COG0667	Aldo Keto reductase
C2H82_RS07765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C2H82_RS07770	COG4589	Belongs to the CDS family
C2H82_RS07775	COG2267	carboxylic ester hydrolase activity
C2H82_RS07780	COG2453	phosphatase
C2H82_RS07780	COG0671	phosphoesterase, PA-phosphatase related
C2H82_RS07790	COG1643	Atp-dependent helicase
C2H82_RS07795	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C2H82_RS07800	COG1012	belongs to the aldehyde dehydrogenase family
C2H82_RS07815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C2H82_RS07820	COG3038	cytochrome b561
C2H82_RS07835	COG0840	transmembrane signaling receptor activity
C2H82_RS07840	COG0583	DNA-binding transcription factor activity
C2H82_RS07845	COG5383	Protein conserved in bacteria
C2H82_RS07865	COG2841	Protein conserved in bacteria
C2H82_RS07870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H82_RS07875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C2H82_RS07880	COG1275	C4-dicarboxylate transporter malic acid transport protein
C2H82_RS07885	COG0500	methyltransferase
C2H82_RS07900	COG0675	Transposase, IS605 OrfB family
C2H82_RS07905	COG3135	benzoate transporter
C2H82_RS07910	COG1396	sequence-specific DNA binding
C2H82_RS07915	COG0826	peptidase U32
C2H82_RS07925	COG1724	mRNA binding
C2H82_RS07930	COG1598	PFAM Uncharacterised protein family UPF0150
C2H82_RS07935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2H82_RS07940	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C2H82_RS07945	COG3842	ATPase activity
C2H82_RS07950	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2H82_RS07955	COG1177	transmembrane transport
C2H82_RS07985	COG3238	Protein conserved in bacteria
C2H82_RS07990	COG1247	-acetyltransferase
C2H82_RS08000	COG2130	NADP-dependent
C2H82_RS08005	COG1802	Transcriptional regulator
C2H82_RS08010	COG4772	TonB-dependent receptor
C2H82_RS08025	COG3391	amine dehydrogenase activity
C2H82_RS08030	COG1113	amino acid transport
C2H82_RS08035	COG0625	glutathione transferase activity
C2H82_RS08050	COG3209	COG3209 Rhs family protein
C2H82_RS08065	COG5433	transposase activity
C2H82_RS08075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C2H82_RS08080	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C2H82_RS08085	COG0384	phenazine biosynthesis protein PhzF
C2H82_RS08090	COG2181	nitrate reductase activity
C2H82_RS08095	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C2H82_RS08100	COG1140	nitrate reductase beta subunit
C2H82_RS08105	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C2H82_RS08110	COG2223	nitrite transmembrane transporter activity
C2H82_RS08120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C2H82_RS08125	COG0697	spore germination
C2H82_RS08130	COG0243	molybdopterin cofactor binding
C2H82_RS08130	COG3383	formate dehydrogenase (NAD+) activity
C2H82_RS08135	COG3383	formate dehydrogenase (NAD+) activity
C2H82_RS08135	COG0243	molybdopterin cofactor binding
C2H82_RS08140	COG0437	4 iron, 4 sulfur cluster binding
C2H82_RS08145	COG2864	formate dehydrogenase
C2H82_RS08150	COG3093	addiction module antidote protein HigA
C2H82_RS08155	COG1064	alcohol dehydrogenase
C2H82_RS08180	COG1764	response to oxidative stress
C2H82_RS08185	COG4608	Belongs to the ABC transporter superfamily
C2H82_RS08190	COG0444	Belongs to the ABC transporter superfamily
C2H82_RS08195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2H82_RS08200	COG0601	transmembrane transport
C2H82_RS08205	COG0747	negative chemotaxis
C2H82_RS08210	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C2H82_RS08215	COG2199	diguanylate cyclase activity
C2H82_RS08215	COG2200	EAL domain
C2H82_RS08215	COG2202	Pas domain
C2H82_RS08220	COG3706	GGDEF domain
C2H82_RS08225	COG1649	PFAM Uncharacterised BCR, COG1649
C2H82_RS08230	COG0531	amino acid
C2H82_RS08235	COG0076	glutamate decarboxylase activity
C2H82_RS08240	COG0612	Peptidase, M16
C2H82_RS08245	COG4771	TonB-dependent receptor
C2H82_RS08250	COG4178	(ABC) transporter
C2H82_RS08255	COG0641	radical SAM
C2H82_RS08260	COG3119	arylsulfatase activity
C2H82_RS08265	COG2207	Transcriptional regulator
C2H82_RS08275	COG0243	molybdopterin cofactor binding
C2H82_RS08280	COG3539	Fimbrial protein
C2H82_RS08285	COG3539	Fimbrial protein
C2H82_RS08290	COG3539	Fimbrial protein
C2H82_RS08310	COG3550	peptidyl-serine autophosphorylation
C2H82_RS08315	COG1396	sequence-specific DNA binding
C2H82_RS08325	COG3210	domain, Protein
C2H82_RS08325	COG2911	Protein conserved in bacteria
C2H82_RS08375	COG3781	membrane
C2H82_RS08395	COG2199	diguanylate cyclase activity
C2H82_RS08405	COG2066	Belongs to the glutaminase family
C2H82_RS08410	COG1012	belongs to the aldehyde dehydrogenase family
C2H82_RS08415	COG0583	DNA-binding transcription factor activity
C2H82_RS08435	COG1846	Transcriptional regulator
C2H82_RS08440	COG4977	sequence-specific DNA binding
C2H82_RS08450	COG0697	spore germination
C2H82_RS08455	COG2814	Major facilitator Superfamily
C2H82_RS08465	COG3706	GGDEF domain
C2H82_RS08470	COG3111	PFAM Bacterial OB fold (BOF) protein
C2H82_RS08475	COG1546	Belongs to the CinA family
C2H82_RS08480	COG0339	signal peptide processing
C2H82_RS08485	COG4221	oxidoreductase activity
C2H82_RS08490	COG1802	Transcriptional regulator
C2H82_RS08500	COG0246	Mannitol dehydrogenase
C2H82_RS08505	COG0477	Major facilitator Superfamily
C2H82_RS08515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2H82_RS08520	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C2H82_RS08525	COG5301	cellulose 1,4-beta-cellobiosidase activity
C2H82_RS08530	COG4220	transposase activity
C2H82_RS08545	COG5562	phage envelope protein
C2H82_RS08565	COG1278	Cold shock
C2H82_RS08575	COG3772	lysozyme
C2H82_RS08590	COG1278	Cold shock
C2H82_RS08595	COG1278	Cold shock
C2H82_RS08600	COG0484	heat shock protein binding
C2H82_RS08605	COG1403	HNH endonuclease
C2H82_RS08625	COG2026	Addiction module toxin, RelE StbE family
C2H82_RS08630	COG3077	Addiction module antitoxin, RelB DinJ family
C2H82_RS08660	COG1396	sequence-specific DNA binding
C2H82_RS08705	COG0582	viral genome integration into host DNA
C2H82_RS08715	COG1063	alcohol dehydrogenase
C2H82_RS08720	COG4948	Mandelate Racemase Muconate Lactonizing
C2H82_RS08740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H82_RS08755	COG0243	molybdopterin cofactor binding
C2H82_RS08760	COG0243	molybdopterin cofactor binding
C2H82_RS08765	COG0437	4 iron, 4 sulfur cluster binding
C2H82_RS08770	COG3302	dmso reductase anchor subunit
C2H82_RS08775	COG3381	protein complex oligomerization
C2H82_RS08785	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C2H82_RS08790	COG1940	carbohydrate kinase activity
C2H82_RS08795	COG0583	DNA-binding transcription factor activity
C2H82_RS08800	COG2814	Major facilitator Superfamily
C2H82_RS08820	COG3591	Belongs to the peptidase S1B family
C2H82_RS08840	COG0628	permease
C2H82_RS08845	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C2H82_RS08850	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C2H82_RS08865	COG0531	amino acid
C2H82_RS08875	COG3136	membrane protein required for alginate biosynthesis
C2H82_RS08880	COG0745	RESPONSE REGULATOR receiver
C2H82_RS08885	COG2205	protein histidine kinase activity
C2H82_RS08895	COG0114	fumarate hydratase activity
C2H82_RS08900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C2H82_RS08900	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C2H82_RS08905	COG1482	cell wall glycoprotein biosynthetic process
C2H82_RS08910	COG5339	Protein conserved in bacteria
C2H82_RS08920	COG2211	Major facilitator Superfamily
C2H82_RS08925	COG3250	beta-galactosidase activity
C2H82_RS08930	COG1309	transcriptional regulator
C2H82_RS08935	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS08940	COG1609	Transcriptional regulator
C2H82_RS08945	COG1263	PTS System
C2H82_RS08945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS08950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C2H82_RS08960	COG0673	inositol 2-dehydrogenase activity
C2H82_RS09005	COG4659	FMN binding
C2H82_RS09015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C2H82_RS09025	COG3104	oligopeptide transport
C2H82_RS09030	COG0625	glutathione transferase activity
C2H82_RS09035	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C2H82_RS09050	COG3895	Periplasmic Protein
C2H82_RS09060	COG3133	Outer membrane lipoprotein
C2H82_RS09075	COG1566	PFAM secretion protein HlyD family protein
C2H82_RS09080	COG1289	transmembrane transporter activity
C2H82_RS09085	COG2032	superoxide dismutase activity
C2H82_RS09090	COG4989	oxidoreductase activity
C2H82_RS09095	COG3313	Fe-S protein
C2H82_RS09100	COG1309	transcriptional regulator
C2H82_RS09105	COG1902	pentaerythritol trinitrate reductase activity
C2H82_RS09110	COG0346	lactoylglutathione lyase activity
C2H82_RS09115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2H82_RS09120	COG1201	RNA secondary structure unwinding
C2H82_RS09125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C2H82_RS09130	COG0791	NLP P60 protein
C2H82_RS09135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C2H82_RS09140	COG2814	Major facilitator Superfamily
C2H82_RS09160	COG0583	DNA-binding transcription factor activity
C2H82_RS09165	COG2814	Major facilitator Superfamily
C2H82_RS09170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C2H82_RS09175	COG0307	riboflavin synthase, alpha
C2H82_RS09185	COG3468	outer membrane autotransporter barrel domain protein
C2H82_RS09205	COG4529	Protein conserved in bacteria
C2H82_RS09215	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C2H82_RS09220	COG0437	4 iron, 4 sulfur cluster binding
C2H82_RS09230	COG2414	aldehyde ferredoxin oxidoreductase
C2H82_RS09235	COG0437	4 iron, 4 sulfur cluster binding
C2H82_RS09245	COG0469	pyruvate kinase activity
C2H82_RS09250	COG4238	major outer membrane lipoprotein
C2H82_RS09255	COG1376	ErfK ybiS ycfS ynhG family protein
C2H82_RS09270	COG0719	Fe-S assembly protein
C2H82_RS09275	COG0396	ATPase activity
C2H82_RS09280	COG0719	Fe-S assembly protein
C2H82_RS09285	COG0316	Belongs to the HesB IscA family
C2H82_RS09295	COG2050	protein possibly involved in aromatic compounds catabolism
C2H82_RS09300	COG0277	FAD linked oxidase domain protein
C2H82_RS09300	COG0247	lactate metabolic process
C2H82_RS09310	COG0628	permease
C2H82_RS09325	COG0738	Major facilitator superfamily
C2H82_RS09330	COG2271	Major facilitator Superfamily
C2H82_RS09345	COG4670	ketone body catabolic process
C2H82_RS09350	COG1960	acyl-CoA dehydrogenase activity
C2H82_RS09355	COG2207	Transcriptional regulator
C2H82_RS09355	COG1917	Cupin 2, conserved barrel domain protein
C2H82_RS09365	COG2086	electron transfer activity
C2H82_RS09370	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C2H82_RS09375	COG0644	oxidoreductase
C2H82_RS09380	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C2H82_RS09385	COG0318	PFAM AMP-dependent synthetase and ligase
C2H82_RS09390	COG0574	Belongs to the PEP-utilizing enzyme family
C2H82_RS09390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2H82_RS09405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C2H82_RS09410	COG4256	Hemin uptake protein
C2H82_RS09420	COG2200	EAL domain
C2H82_RS09425	COG0791	NLP P60 protein
C2H82_RS09435	COG0386	Belongs to the glutathione peroxidase family
C2H82_RS09450	COG0072	phenylalanine-tRNA ligase activity
C2H82_RS09450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2H82_RS09500	COG3137	Salt-induced outer membrane protein
C2H82_RS09505	COG1105	Belongs to the carbohydrate kinase PfkB family
C2H82_RS09515	COG3001	Fructosamine kinase
C2H82_RS09525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2H82_RS09530	COG1988	membrane-bound metal-dependent
C2H82_RS09535	COG1823	symporter activity
C2H82_RS09550	COG0753	catalase activity
C2H82_RS09560	COG1486	melibiose metabolic process
C2H82_RS09565	COG1917	Cupin 2, conserved barrel domain protein
C2H82_RS09565	COG2169	Transcriptional regulator
C2H82_RS09570	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2H82_RS09575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2H82_RS09580	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2H82_RS09590	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2H82_RS09600	COG0322	excinuclease ABC activity
C2H82_RS09610	COG3678	ATP-independent chaperone mediated protein folding
C2H82_RS09645	COG0708	Exodeoxyribonuclease III
C2H82_RS09650	COG0398	Pfam SNARE associated Golgi protein
C2H82_RS09660	COG0398	Pfam SNARE associated Golgi protein
C2H82_RS09665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2H82_RS09670	COG4134	Bacterial extracellular solute-binding protein
C2H82_RS09675	COG4135	transport system, permease component
C2H82_RS09680	COG4136	ATPase activity
C2H82_RS09685	COG2897	thiosulfate sulfurtransferase activity
C2H82_RS09690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C2H82_RS09695	COG0494	nUDIX hydrolase
C2H82_RS09705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C2H82_RS09715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C2H82_RS09730	COG0778	Nitroreductase
C2H82_RS09740	COG0616	signal peptide processing
C2H82_RS09745	COG0252	asparaginase activity
C2H82_RS09750	COG1335	isochorismatase
C2H82_RS09755	COG2814	Major facilitator Superfamily
C2H82_RS09760	COG1349	DNA-binding transcription factor activity
C2H82_RS09765	COG0667	Aldo Keto reductase
C2H82_RS09770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H82_RS09775	COG0191	fructose-bisphosphate aldolase activity
C2H82_RS09780	COG1063	alcohol dehydrogenase
C2H82_RS09785	COG2271	Major facilitator Superfamily
C2H82_RS09790	COG1063	alcohol dehydrogenase
C2H82_RS09795	COG3139	Protein of unknown function (DUF1315)
C2H82_RS09805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C2H82_RS09810	COG0676	glucose-6-phosphate 1-epimerase activity
C2H82_RS09815	COG0656	L-ascorbic acid biosynthetic process
C2H82_RS09820	COG3713	MltA-interacting MipA family protein
C2H82_RS09825	COG2766	serine protein kinase
C2H82_RS09835	COG2199	diguanylate cyclase activity
C2H82_RS09840	COG2199	diguanylate cyclase activity
C2H82_RS09845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2H82_RS09860	COG2207	Transcriptional regulator
C2H82_RS09865	COG2807	transmembrane transport
C2H82_RS09870	COG3189	MarR family transcriptional regulator
C2H82_RS09875	COG3042	response to heat
C2H82_RS09880	COG2203	Gaf domain
C2H82_RS09880	COG2199	diguanylate cyclase activity
C2H82_RS09895	COG2261	transglycosylase associated protein
C2H82_RS09905	COG3615	Tellurite resistance protein tehB
C2H82_RS09915	COG0583	DNA-binding transcription factor activity
C2H82_RS09920	COG0473	3-isopropylmalate dehydrogenase activity
C2H82_RS09925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C2H82_RS09930	COG4638	Rieske (2fe-2S)
C2H82_RS09935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2H82_RS09940	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C2H82_RS09945	COG0318	PFAM AMP-dependent synthetase and ligase
C2H82_RS09950	COG3065	identical protein binding
C2H82_RS09955	COG1214	PFAM Peptidase M22, glycoprotease
C2H82_RS09960	COG1199	ATP-dependent helicase activity
C2H82_RS09965	COG0251	oxidation-reduction process
C2H82_RS09980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C2H82_RS09990	COG1760	l-serine dehydratase
C2H82_RS09995	COG2200	EAL domain
C2H82_RS10000	COG1253	flavin adenine dinucleotide binding
C2H82_RS10015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS10015	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS10020	COG3715	PTS system
C2H82_RS10025	COG3716	PTS system mannose fructose sorbose family IID component
C2H82_RS10045	COG2226	methyltransferase
C2H82_RS10080	COG1414	Transcriptional regulator
C2H82_RS10085	COG2814	Major facilitator Superfamily
C2H82_RS10095	COG0793	Belongs to the peptidase S41A family
C2H82_RS10105	COG1956	GAF domain-containing protein
C2H82_RS10110	COG2995	paraquat-inducible protein a
C2H82_RS10115	COG3008	intermembrane lipid transfer
C2H82_RS10135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C2H82_RS10145	COG1276	copper resistance
C2H82_RS10150	COG2372	response to copper ion
C2H82_RS10160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2H82_RS10165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2H82_RS10170	COG1770	oligopeptidase
C2H82_RS10175	COG2979	Protein of unknown function (DUF533)
C2H82_RS10185	COG3141	response to X-ray
C2H82_RS10195	COG0800	Aldolase
C2H82_RS10200	COG0129	dihydroxy-acid dehydratase activity
C2H82_RS10205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C2H82_RS10210	COG1737	Transcriptional regulator
C2H82_RS10215	COG0469	pyruvate kinase activity
C2H82_RS10220	COG1560	Kdo2-lipid A biosynthetic process
C2H82_RS10225	COG0739	heme binding
C2H82_RS10230	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C2H82_RS10240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2H82_RS10270	COG0217	transcriptional regulatory protein
C2H82_RS10275	COG0494	nUDIX hydrolase
C2H82_RS10285	COG1335	isochorismatase
C2H82_RS10290	COG1801	Protein of unknown function DUF72
C2H82_RS10295	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C2H82_RS10310	COG0243	molybdopterin cofactor binding
C2H82_RS10315	COG3005	denitrification pathway
C2H82_RS10325	COG3102	Protein conserved in bacteria
C2H82_RS10340	COG3755	Protein conserved in bacteria
C2H82_RS10350	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C2H82_RS10355	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C2H82_RS10360	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C2H82_RS10365	COG0745	RESPONSE REGULATOR receiver
C2H82_RS10370	COG2201	protein-glutamate methylesterase activity
C2H82_RS10375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C2H82_RS10380	COG0840	transmembrane signaling receptor activity
C2H82_RS10385	COG0840	transmembrane signaling receptor activity
C2H82_RS10390	COG0835	chemotaxis
C2H82_RS10410	COG0589	response to stress
C2H82_RS10420	COG1877	trehalose-phosphatase activity
C2H82_RS10425	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2H82_RS10430	COG1129	ABC transporter
C2H82_RS10435	COG1879	ABC-type sugar transport system periplasmic component
C2H82_RS10445	COG1528	Iron-storage protein
C2H82_RS10465	COG1528	Iron-storage protein
C2H82_RS10475	COG0814	amino acid
C2H82_RS10480	COG3318	Belongs to the UPF0149 family
C2H82_RS10480	COG3012	SEC-C Motif Domain Protein
C2H82_RS10510	COG2197	response regulator
C2H82_RS10520	COG2197	response regulator
C2H82_RS10525	COG1126	abc transporter atp-binding protein
C2H82_RS10530	COG0765	amino acid transport
C2H82_RS10540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H82_RS10550	COG1191	sigma factor activity
C2H82_RS10555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C2H82_RS10565	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C2H82_RS10570	COG1516	flagellar protein fliS
C2H82_RS10580	COG0366	Alpha amylase catalytic
C2H82_RS10595	COG2391	methyltransferase activity
C2H82_RS10600	COG0425	Belongs to the sulfur carrier protein TusA family
C2H82_RS10605	COG2135	peptidase activity
C2H82_RS10610	COG0454	-acetyltransferase
C2H82_RS10640	COG1766	The M ring may be actively involved in energy transduction
C2H82_RS10645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2H82_RS10650	COG1317	bacterial-type flagellum organization
C2H82_RS10655	COG1157	protein secretion by the type III secretion system
C2H82_RS10660	COG2882	bacterial-type flagellum organization
C2H82_RS10665	COG3144	bacterial-type flagellum assembly
C2H82_RS10670	COG1580	Controls the rotational direction of flagella during chemotaxis
C2H82_RS10675	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2H82_RS10680	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2H82_RS10685	COG3190	flagellar
C2H82_RS10690	COG1338	Plays a role in the flagellum-specific transport system
C2H82_RS10695	COG1987	bacterial-type flagellum assembly
C2H82_RS10700	COG1684	flagellar biosynthetic protein fliR
C2H82_RS10705	COG2197	response regulator
C2H82_RS10725	COG3706	GGDEF domain
C2H82_RS10735	COG5475	Uncharacterized small protein (DUF2158)
C2H82_RS10740	COG2354	Protein conserved in bacteria
C2H82_RS10745	COG0697	spore germination
C2H82_RS10750	COG3727	T/G mismatch-specific endonuclease activity
C2H82_RS10755	COG0270	DNA (cytosine-5-)-methyltransferase activity
C2H82_RS10760	COG1418	mRNA catabolic process
C2H82_RS10785	COG2205	protein histidine kinase activity
C2H82_RS10790	COG0745	RESPONSE REGULATOR receiver
C2H82_RS10795	COG2351	hydroxyisourate hydrolase activity
C2H82_RS10800	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C2H82_RS10810	COG3443	Belongs to the bacterial solute-binding protein 9 family
C2H82_RS10815	COG3038	cytochrome b561
C2H82_RS10840	COG1388	LysM domain
C2H82_RS10840	COG1470	cell adhesion involved in biofilm formation
C2H82_RS10850	COG0477	Major facilitator Superfamily
C2H82_RS10855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C2H82_RS10860	COG0217	transcriptional regulatory protein
C2H82_RS10880	COG0534	Mate efflux family protein
C2H82_RS10890	COG0583	DNA-binding transcription factor activity
C2H82_RS10895	COG0583	DNA-binding transcription factor activity
C2H82_RS10905	COG1376	ErfK ybiS ycfS ynhG family protein
C2H82_RS10920	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C2H82_RS10930	COG3039	Transposase
C2H82_RS10950	COG4771	TonB-dependent receptor
C2H82_RS10960	COG4771	TonB-dependent receptor
C2H82_RS10970	COG3468	outer membrane autotransporter barrel domain protein
C2H82_RS10975	COG2020	methyltransferase activity
C2H82_RS10980	COG2003	Belongs to the UPF0758 family
C2H82_RS11020	COG1289	transmembrane transporter activity
C2H82_RS11030	COG1686	Belongs to the peptidase S11 family
C2H82_RS11035	COG2925	Exonuclease
C2H82_RS11040	COG0425	Belongs to the sulfur carrier protein TusA family
C2H82_RS11045	COG2391	methyltransferase activity
C2H82_RS11050	COG0531	amino acid
C2H82_RS11060	COG0583	DNA-binding transcription factor activity
C2H82_RS11065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2H82_RS11070	COG4115	mRNA cleavage
C2H82_RS11075	COG2161	toxin-antitoxin pair type II binding
C2H82_RS11095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C2H82_RS11105	COG0131	Imidazoleglycerol-phosphate dehydratase
C2H82_RS11105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C2H82_RS11110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C2H82_RS11125	COG0140	phosphoribosyl-ATP diphosphatase activity
C2H82_RS11125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C2H82_RS11130	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C2H82_RS11135	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C2H82_RS11140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C2H82_RS11165	COG0438	transferase activity, transferring glycosyl groups
C2H82_RS11170	COG0110	maltose O-acetyltransferase activity
C2H82_RS11175	COG0438	transferase activity, transferring glycosyl groups
C2H82_RS11185	COG0562	UDP-galactopyranose mutase
C2H82_RS11190	COG2244	polysaccharide biosynthetic process
C2H82_RS11195	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C2H82_RS11200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C2H82_RS11205	COG1091	dTDP-4-dehydrorhamnose reductase activity
C2H82_RS11210	COG1088	dTDP-glucose 4,6-dehydratase activity
C2H82_RS11220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C2H82_RS11230	COG0438	transferase activity, transferring glycosyl groups
C2H82_RS11235	COG2327	Polysaccharide pyruvyl transferase
C2H82_RS11240	COG2244	polysaccharide biosynthetic process
C2H82_RS11245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C2H82_RS11250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C2H82_RS11255	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C2H82_RS11255	COG0662	Cupin 2, conserved barrel domain protein
C2H82_RS11260	COG0297	glycogen (starch) synthase activity
C2H82_RS11265	COG1051	belongs to the nudix hydrolase family
C2H82_RS11270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2H82_RS11275	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C2H82_RS11280	COG0110	maltose O-acetyltransferase activity
C2H82_RS11285	COG1216	Glycosyl transferase, family 2
C2H82_RS11295	COG0438	transferase activity, transferring glycosyl groups
C2H82_RS11300	COG1045	serine acetyltransferase
C2H82_RS11305	COG0463	Glycosyl transferase, family 2
C2H82_RS11310	COG0489	protein tyrosine kinase activity
C2H82_RS11310	COG3206	protein involved in exopolysaccharide biosynthesis
C2H82_RS11315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C2H82_RS11320	COG1596	polysaccharide export
C2H82_RS11325	COG1253	flavin adenine dinucleotide binding
C2H82_RS11330	COG2982	Protein involved in outer membrane biogenesis
C2H82_RS11340	COG0572	uridine kinase
C2H82_RS11345	COG5001	Diguanylate cyclase
C2H82_RS11345	COG5002	protein histidine kinase activity
C2H82_RS11345	COG3447	MASE1 domain protein
C2H82_RS11350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C2H82_RS11360	COG0443	Heat shock 70 kDa protein
C2H82_RS11365	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C2H82_RS11370	COG3779	Protein conserved in bacteria
C2H82_RS11375	COG0631	protein serine/threonine phosphatase activity
C2H82_RS11380	COG4245	von Willebrand factor, type A
C2H82_RS11415	COG2205	protein histidine kinase activity
C2H82_RS11420	COG0745	RESPONSE REGULATOR receiver
C2H82_RS11425	COG3422	double-strand break repair
C2H82_RS11430	COG0826	peptidase U32
C2H82_RS11475	COG1063	alcohol dehydrogenase
C2H82_RS11480	COG3775	system Galactitol-specific IIC component
C2H82_RS11485	COG3414	Phosphotransferase system galactitol-specific IIB component
C2H82_RS11490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS11505	COG1830	Aldolase
C2H82_RS11510	COG2211	Major facilitator Superfamily
C2H82_RS11515	COG1397	ADP-ribosylglycohydrolase
C2H82_RS11520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H82_RS11525	COG2188	Transcriptional regulator
C2H82_RS11530	COG3757	hydrolase, family 25
C2H82_RS11535	COG0351	phosphomethylpyrimidine kinase
C2H82_RS11550	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C2H82_RS11555	COG5455	response to cobalt ion
C2H82_RS11560	COG3539	Fimbrial protein
C2H82_RS11565	COG3188	usher protein
C2H82_RS11570	COG3121	Chaperone
C2H82_RS11575	COG3539	Fimbrial protein
C2H82_RS11590	COG0489	protein tyrosine kinase activity
C2H82_RS11615	COG3831	ATPase activity
C2H82_RS11625	COG0714	Associated with various cellular activities
C2H82_RS11630	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C2H82_RS11635	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C2H82_RS11640	COG4715	Zinc finger, swim domain protein
C2H82_RS11645	COG4808	Protein conserved in bacteria
C2H82_RS11650	COG4807	Protein conserved in bacteria
C2H82_RS11655	COG3279	Response regulator of the LytR AlgR family
C2H82_RS11660	COG3275	phosphorelay sensor kinase activity
C2H82_RS11665	COG0789	Transcriptional regulator
C2H82_RS11675	COG1174	glycine betaine transport
C2H82_RS11680	COG1125	glycine betaine transport
C2H82_RS11685	COG1174	glycine betaine transport
C2H82_RS11690	COG1732	Glycine betaine
C2H82_RS11695	COG1472	Belongs to the glycosyl hydrolase 3 family
C2H82_RS11700	COG0277	FAD linked oxidase domain protein
C2H82_RS11705	COG1686	Belongs to the peptidase S11 family
C2H82_RS11715	COG0586	Pfam SNARE associated Golgi protein
C2H82_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS11745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2H82_RS11755	COG1346	cytolysis
C2H82_RS11765	COG2949	membrane
C2H82_RS11775	COG0493	'glutamate synthase
C2H82_RS11780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C2H82_RS11780	COG0167	dihydroorotate dehydrogenase activity
C2H82_RS11785	COG4211	Belongs to the binding-protein-dependent transport system permease family
C2H82_RS11790	COG1129	ABC transporter
C2H82_RS11795	COG1879	ABC-type sugar transport system periplasmic component
C2H82_RS11800	COG1609	Transcriptional regulator
C2H82_RS11810	COG2311	Membrane
C2H82_RS11835	COG4771	TonB-dependent receptor
C2H82_RS11845	COG0833	amino acid
C2H82_RS11855	COG0583	DNA-binding transcription factor activity
C2H82_RS11860	COG2855	membrane
C2H82_RS11870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H82_RS11870	COG1522	sequence-specific DNA binding
C2H82_RS11875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2H82_RS11885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2H82_RS11890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2H82_RS11895	COG2313	pseudouridylate synthase activity
C2H82_RS11900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H82_RS11905	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C2H82_RS11905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS11905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS11910	COG1105	Belongs to the carbohydrate kinase PfkB family
C2H82_RS11915	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS11915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS11920	COG2814	Major facilitator Superfamily
C2H82_RS11935	COG0246	Mannitol dehydrogenase
C2H82_RS11940	COG0523	cobalamin synthesis protein
C2H82_RS11945	COG0671	phosphoesterase, PA-phosphatase related
C2H82_RS11950	COG0791	NLP P60 protein
C2H82_RS11955	COG2200	EAL domain
C2H82_RS11960	COG4166	transmembrane transport
C2H82_RS11965	COG4174	ABC transporter (Permease)
C2H82_RS11970	COG4239	(ABC) transporter, permease
C2H82_RS11975	COG4172	Belongs to the ABC transporter superfamily
C2H82_RS11990	COG2814	Major facilitator Superfamily
C2H82_RS11995	COG1187	pseudouridine synthase activity
C2H82_RS12005	COG1061	Type III restriction enzyme res subunit
C2H82_RS12025	COG3083	sulfuric ester hydrolase activity
C2H82_RS12040	COG3468	outer membrane autotransporter barrel domain protein
C2H82_RS12065	COG2197	response regulator
C2H82_RS12070	COG4235	cytochrome complex assembly
C2H82_RS12070	COG3088	subunit of a heme lyase
C2H82_RS12075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H82_RS12080	COG1138	Cytochrome C-type biogenesis protein
C2H82_RS12090	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2H82_RS12095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2H82_RS12100	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2H82_RS12105	COG4133	protoheme IX ABC transporter activity
C2H82_RS12110	COG3005	denitrification pathway
C2H82_RS12115	COG3043	anaerobic respiration
C2H82_RS12120	COG0348	domain, Protein
C2H82_RS12125	COG0437	4 iron, 4 sulfur cluster binding
C2H82_RS12135	COG3062	negative regulation of establishment of protein localization
C2H82_RS12140	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS12140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS12160	COG4615	Cyclic peptide transporter
C2H82_RS12165	COG3145	DNA-N1-methyladenine dioxygenase activity
C2H82_RS12170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C2H82_RS12170	COG2169	Transcriptional regulator
C2H82_RS12175	COG1477	protein flavinylation
C2H82_RS12180	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C2H82_RS12195	COG2198	Histidine kinase
C2H82_RS12195	COG0642	Histidine kinase
C2H82_RS12200	COG2197	response regulator
C2H82_RS12205	COG2205	protein histidine kinase activity
C2H82_RS12205	COG0784	Response regulator, receiver
C2H82_RS12210	COG3852	Histidine kinase
C2H82_RS12215	COG2204	response regulator
C2H82_RS12220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C2H82_RS12225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C2H82_RS12230	COG2031	fatty acid transporter
C2H82_RS12235	COG0183	Belongs to the thiolase family
C2H82_RS12240	COG4676	Protein conserved in bacteria
C2H82_RS12245	COG5445	Predicted secreted protein (DUF2300)
C2H82_RS12250	COG2373	Large extracellular alpha-helical protein
C2H82_RS12260	COG3234	Protein of unknown function (DUF1175)
C2H82_RS12265	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C2H82_RS12270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C2H82_RS12280	COG3468	outer membrane autotransporter barrel domain protein
C2H82_RS12290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2H82_RS12295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2H82_RS12300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2H82_RS12305	COG3642	lipopolysaccharide core region biosynthetic process
C2H82_RS12310	COG0583	DNA-binding transcription factor activity
C2H82_RS12315	COG0584	glycerophosphoryl diester phosphodiesterase
C2H82_RS12320	COG2271	Major facilitator Superfamily
C2H82_RS12325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C2H82_RS12335	COG0247	lactate metabolic process
C2H82_RS12340	COG5464	transposase or invertase
C2H82_RS12355	COG2271	Major facilitator Superfamily
C2H82_RS12365	COG1414	Transcriptional regulator
C2H82_RS12430	COG0318	PFAM AMP-dependent synthetase and ligase
C2H82_RS12440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C2H82_RS12455	COG1169	isochorismate synthase
C2H82_RS12460	COG4575	ribosome binding
C2H82_RS12465	COG2153	protein acetylation
C2H82_RS12475	COG5160	protein modification by small protein removal
C2H82_RS12480	COG2304	oxidoreductase activity
C2H82_RS12485	COG2234	aminopeptidase activity
C2H82_RS12505	COG0457	Tetratricopeptide repeat
C2H82_RS12515	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2H82_RS12520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C2H82_RS12530	COG0839	Belongs to the complex I subunit 6 family
C2H82_RS12545	COG1034	ATP synthesis coupled electron transport
C2H82_RS12550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C2H82_RS12555	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C2H82_RS12575	COG0583	DNA-binding transcription factor activity
C2H82_RS12585	COG0436	Aminotransferase
C2H82_RS12595	COG0490	domain, Protein
C2H82_RS12595	COG0471	metal ion transport
C2H82_RS12600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2H82_RS12615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C2H82_RS12620	COG0857	belongs to the CobB CobQ family
C2H82_RS12620	COG0280	phosphate acetyltransferase
C2H82_RS12625	COG1288	antiporter activity
C2H82_RS12630	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C2H82_RS12635	COG0622	Phosphoesterase
C2H82_RS12640	COG0625	glutathione transferase activity
C2H82_RS12645	COG0625	glutathione transferase activity
C2H82_RS12650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C2H82_RS12655	COG1090	epimerase
C2H82_RS12660	COG5464	transposase or invertase
C2H82_RS12665	COG4598	ABC transporter
C2H82_RS12670	COG4160	amino acid transport
C2H82_RS12675	COG4215	(ABC) transporter
C2H82_RS12680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H82_RS12685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H82_RS12690	COG0163	prenyltransferase activity
C2H82_RS12695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C2H82_RS12700	COG1286	toxin biosynthetic process
C2H82_RS12705	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C2H82_RS12710	COG0285	dihydrofolate synthase activity
C2H82_RS12720	COG0586	Pfam SNARE associated Golgi protein
C2H82_RS12730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C2H82_RS12745	COG2814	Major facilitator Superfamily
C2H82_RS12755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2H82_RS12770	COG3101	peptidyl-lysine hydroxylation
C2H82_RS12775	COG0730	response to heat
C2H82_RS12790	COG2890	protein-(glutamine-N5) methyltransferase activity
C2H82_RS12805	COG3539	Fimbrial protein
C2H82_RS12810	COG3539	Fimbrial protein
C2H82_RS12815	COG3539	Fimbrial protein
C2H82_RS12820	COG3121	Chaperone
C2H82_RS12830	COG3539	Fimbrial protein
C2H82_RS12835	COG2062	phosphohistidine phosphatase, SixA
C2H82_RS12850	COG3691	Protein conserved in bacteria
C2H82_RS12860	COG2067	long-chain fatty acid transport protein
C2H82_RS12875	COG2853	Lipoprotein
C2H82_RS12885	COG2116	formate transmembrane transporter activity
C2H82_RS12895	COG0582	viral genome integration into host DNA
C2H82_RS12900	COG2246	polysaccharide biosynthetic process
C2H82_RS12905	COG0463	Glycosyl transferase, family 2
C2H82_RS12930	COG4725	Belongs to the MT-A70-like family
C2H82_RS12950	COG5532	Uncharacterized conserved protein (DUF2303)
C2H82_RS12955	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C2H82_RS12975	COG0583	DNA-binding transcription factor activity
C2H82_RS12980	COG2610	gluconate transmembrane transporter activity
C2H82_RS12990	COG0477	Major facilitator Superfamily
C2H82_RS12995	COG1566	PFAM secretion protein HlyD family protein
C2H82_RS13000	COG2197	response regulator
C2H82_RS13005	COG2198	Histidine kinase
C2H82_RS13005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H82_RS13005	COG2205	protein histidine kinase activity
C2H82_RS13005	COG0784	Response regulator, receiver
C2H82_RS13010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C2H82_RS13015	COG0679	Auxin Efflux Carrier
C2H82_RS13020	COG0028	Belongs to the TPP enzyme family
C2H82_RS13050	COG1560	Kdo2-lipid A biosynthetic process
C2H82_RS13060	COG0436	Aminotransferase
C2H82_RS13065	COG3275	phosphorelay sensor kinase activity
C2H82_RS13070	COG3279	Response regulator of the LytR AlgR family
C2H82_RS13075	COG2207	Transcriptional regulator
C2H82_RS13080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS13080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2H82_RS13080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS13085	COG1363	Peptidase, m42
C2H82_RS13090	COG0006	proline dipeptidase activity
C2H82_RS13095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS13100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS13125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2H82_RS13130	COG3385	transposase activity
C2H82_RS13135	COG2199	diguanylate cyclase activity
C2H82_RS13135	COG2200	EAL domain
C2H82_RS13150	COG3415	Transposase
C2H82_RS13155	COG3415	Transposase
C2H82_RS13190	COG0583	DNA-binding transcription factor activity
C2H82_RS13200	COG2211	Major facilitator Superfamily
C2H82_RS13205	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C2H82_RS13215	COG0583	DNA-binding transcription factor activity
C2H82_RS13220	COG0385	Bile acid
C2H82_RS13225	COG3530	Putative quorum-sensing-regulated virulence factor
C2H82_RS13245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C2H82_RS13250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS13255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2H82_RS13260	COG2190	(PTS) system
C2H82_RS13275	COG4884	unkown
C2H82_RS13275	COG3831	ATPase activity
C2H82_RS13280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C2H82_RS13285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C2H82_RS13290	COG4208	sulfate ABC transporter
C2H82_RS13295	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C2H82_RS13300	COG4150	thiosulfate binding
C2H82_RS13310	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS13325	COG1263	PTS System
C2H82_RS13325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS13330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C2H82_RS13335	COG2837	iron assimilation
C2H82_RS13350	COG0456	acetyltransferase
C2H82_RS13355	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2H82_RS13365	COG2207	Transcriptional regulator
C2H82_RS13370	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C2H82_RS13375	COG4816	utilization protein
C2H82_RS13385	COG4303	Ethanolamine ammonia lyase large subunit
C2H82_RS13390	COG0582	viral genome integration into host DNA
C2H82_RS13435	COG4819	ethanolamine utilization protein
C2H82_RS13440	COG3192	ethanolamine utilization protein
C2H82_RS13445	COG1454	alcohol dehydrogenase
C2H82_RS13450	COG4820	ethanolamine utilization protein (EutJ)
C2H82_RS13455	COG1012	belongs to the aldehyde dehydrogenase family
C2H82_RS13460	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C2H82_RS13465	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C2H82_RS13470	COG0280	phosphate acetyltransferase
C2H82_RS13475	COG4812	Cobalamin adenosyltransferase
C2H82_RS13480	COG4766	ethanolamine catabolic process
C2H82_RS13485	COG4917	ethanolamine utilization protein
C2H82_RS13490	COG4810	utilization protein
C2H82_RS13495	COG0280	phosphate acetyltransferase
C2H82_RS13495	COG0281	malic enzyme
C2H82_RS13500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C2H82_RS13505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C2H82_RS13510	COG5342	invasion associated locus B
C2H82_RS13520	COG0493	'glutamate synthase
C2H82_RS13520	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS13525	COG3850	Histidine kinase
C2H82_RS13530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2H82_RS13540	COG1393	Belongs to the ArsC family
C2H82_RS13555	COG0400	carboxylic ester hydrolase activity
C2H82_RS13560	COG1444	tRNA N-acetyltransferase activity
C2H82_RS13565	COG2321	neutral zinc metallopeptidase
C2H82_RS13575	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C2H82_RS13585	COG2716	regulation of RNA biosynthetic process
C2H82_RS13590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2H82_RS13595	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS13600	COG0651	ATP synthesis coupled electron transport
C2H82_RS13605	COG0650	Formate hydrogenlyase subunit 4
C2H82_RS13610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C2H82_RS13615	COG4237	Hydrogenase 4 membrane
C2H82_RS13620	COG0651	ATP synthesis coupled electron transport
C2H82_RS13625	COG3261	NADH dehydrogenase
C2H82_RS13625	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C2H82_RS13630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2H82_RS13635	COG3260	NADH ubiquinone oxidoreductase 20
C2H82_RS13645	COG3604	Transcriptional regulator
C2H82_RS13650	COG2116	formate transmembrane transporter activity
C2H82_RS13660	COG0628	permease
C2H82_RS13665	COG4783	chaperone-mediated protein folding
C2H82_RS13670	COG1393	Belongs to the ArsC family
C2H82_RS13680	COG2233	PERMEase
C2H82_RS13700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C2H82_RS13705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C2H82_RS13710	COG0248	Ppx GppA phosphatase
C2H82_RS13715	COG2200	EAL domain
C2H82_RS13735	COG3133	Outer membrane lipoprotein
C2H82_RS13750	COG0517	IMP dehydrogenase activity
C2H82_RS13750	COG0516	GMP reductase activity
C2H82_RS13760	COG1645	bacterial-type flagellum-dependent swarming motility
C2H82_RS13770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2H82_RS13775	COG2976	Protein conserved in bacteria
C2H82_RS13810	COG4953	penicillin-binding protein 1C
C2H82_RS13815	COG2373	Large extracellular alpha-helical protein
C2H82_RS13820	COG2897	thiosulfate sulfurtransferase activity
C2H82_RS13835	COG2975	iron-sulfur cluster assembly
C2H82_RS13840	COG0633	Ferredoxin
C2H82_RS13860	COG0822	iron-sulfur transferase activity
C2H82_RS13880	COG0483	inositol monophosphate 1-phosphatase activity
C2H82_RS13885	COG1073	alpha beta
C2H82_RS13890	COG3711	transcriptional antiterminator
C2H82_RS13895	COG2814	Major facilitator Superfamily
C2H82_RS13900	COG0583	DNA-binding transcription factor activity
C2H82_RS13905	COG4638	Rieske (2fe-2S)
C2H82_RS13930	COG2259	Doxx family
C2H82_RS13935	COG2017	converts alpha-aldose to the beta-anomer
C2H82_RS13940	COG1063	alcohol dehydrogenase
C2H82_RS13945	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2H82_RS13950	COG1129	ABC transporter
C2H82_RS13955	COG1879	ABC-type sugar transport system periplasmic component
C2H82_RS13960	COG0457	Tetratricopeptide repeat
C2H82_RS13965	COG1940	carbohydrate kinase activity
C2H82_RS13975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2H82_RS13975	COG1017	nitric oxide dioxygenase activity
C2H82_RS13980	COG0347	Belongs to the P(II) protein family
C2H82_RS13985	COG2204	response regulator
C2H82_RS13990	COG3170	Tfp pilus assembly protein FimV
C2H82_RS13995	COG2205	protein histidine kinase activity
C2H82_RS14000	COG0047	phosphoribosylformylglycinamidine synthase activity
C2H82_RS14000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C2H82_RS14020	COG0560	Phosphoserine phosphatase
C2H82_RS14025	COG1737	Transcriptional regulator
C2H82_RS14030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS14055	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C2H82_RS14080	COG0681	Belongs to the peptidase S26 family
C2H82_RS14090	COG3086	response to oxidative stress
C2H82_RS14095	COG3026	antisigma factor binding
C2H82_RS14100	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C2H82_RS14105	COG1595	DNA-templated transcription, initiation
C2H82_RS14110	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C2H82_RS14120	COG0513	Belongs to the DEAD box helicase family
C2H82_RS14125	COG0583	DNA-binding transcription factor activity
C2H82_RS14145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2H82_RS14155	COG3118	belongs to the thioredoxin family
C2H82_RS14160	COG3148	PFAM DTW domain containing protein
C2H82_RS14165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H82_RS14165	COG1042	CoA-binding domain protein
C2H82_RS14165	COG0045	succinate-CoA ligase (ADP-forming) activity
C2H82_RS14170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2H82_RS14175	COG5544	Lipoprotein
C2H82_RS14180	COG0477	Major facilitator Superfamily
C2H82_RS14210	COG0542	response to heat
C2H82_RS14215	COG1496	oxidoreductase activity
C2H82_RS14220	COG0564	pseudouridine synthase activity
C2H82_RS14225	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2H82_RS14235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C2H82_RS14245	COG0077	Prephenate dehydratase
C2H82_RS14245	COG1605	Chorismate mutase
C2H82_RS14250	COG1605	Chorismate mutase
C2H82_RS14250	COG0287	Prephenate dehydrogenase
C2H82_RS14255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C2H82_RS14270	COG2199	diguanylate cyclase activity
C2H82_RS14275	COG2885	chlorophyll binding
C2H82_RS14300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C2H82_RS14305	COG4137	Cytochrome C assembly protein
C2H82_RS14310	COG4536	flavin adenine dinucleotide binding
C2H82_RS14330	COG0497	DNA recombination
C2H82_RS14335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2H82_RS14345	COG2867	negative regulation of translational initiation
C2H82_RS14360	COG0582	viral genome integration into host DNA
C2H82_RS14370	COG3311	Transcriptional regulator
C2H82_RS14375	COG4983	Phage plasmid primase, P4 family domain protein
C2H82_RS14385	COG1204	response to ionizing radiation
C2H82_RS14395	COG1479	Protein of unknown function DUF262
C2H82_RS14410	COG3596	GTP binding
C2H82_RS14420	COG2378	regulation of single-species biofilm formation
C2H82_RS14465	COG2003	Belongs to the UPF0758 family
C2H82_RS14485	COG3468	outer membrane autotransporter barrel domain protein
C2H82_RS14515	COG0366	Alpha amylase catalytic
C2H82_RS14535	COG0579	oxidoreductase
C2H82_RS14540	COG1012	belongs to the aldehyde dehydrogenase family
C2H82_RS14545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C2H82_RS14550	COG1113	amino acid transport
C2H82_RS14555	COG1802	Transcriptional regulator
C2H82_RS14560	COG1652	LysM domain
C2H82_RS14565	COG0401	homolog of Blt101
C2H82_RS14570	COG0640	Transcriptional regulator
C2H82_RS14575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2H82_RS14580	COG2916	Histone family protein nucleoid-structuring protein H-NS
C2H82_RS14595	COG4575	ribosome binding
C2H82_RS14600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C2H82_RS14630	COG1238	metal cluster binding
C2H82_RS14635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2H82_RS14665	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C2H82_RS14685	COG1546	Belongs to the CinA family
C2H82_RS14690	COG2951	lytic endotransglycosylase activity
C2H82_RS14695	COG3730	PTS system glucitol sorbitol-specific
C2H82_RS14700	COG3732	PTS system glucitol sorbitol-specific
C2H82_RS14705	COG3731	PTS system glucitol sorbitol-specific IIA component
C2H82_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS14715	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS14720	COG1349	DNA-binding transcription factor activity
C2H82_RS14725	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C2H82_RS14725	COG0517	IMP dehydrogenase activity
C2H82_RS14745	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C2H82_RS14750	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS14755	COG1609	Transcriptional regulator
C2H82_RS14760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS14760	COG1263	PTS System
C2H82_RS14765	COG2723	6-phospho-beta-galactosidase activity
C2H82_RS14770	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C2H82_RS14780	COG3260	NADH ubiquinone oxidoreductase 20
C2H82_RS14785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2H82_RS14790	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C2H82_RS14790	COG3261	NADH dehydrogenase
C2H82_RS14795	COG0650	Formate hydrogenlyase subunit 4
C2H82_RS14800	COG0651	ATP synthesis coupled electron transport
C2H82_RS14805	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS14815	COG0375	protein maturation
C2H82_RS14820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C2H82_RS14825	COG0298	carbon dioxide binding
C2H82_RS14830	COG0409	Hydrogenase expression formation protein
C2H82_RS14835	COG0309	Hydrogenase expression formation protein (HypE)
C2H82_RS14840	COG3604	Transcriptional regulator
C2H82_RS14855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C2H82_RS14860	COG1349	DNA-binding transcription factor activity
C2H82_RS14865	COG2084	Dehydrogenase
C2H82_RS14870	COG3395	kinase activity
C2H82_RS14875	COG0235	Class ii aldolase
C2H82_RS14880	COG3622	Belongs to the hyi family
C2H82_RS14885	COG2610	gluconate transmembrane transporter activity
C2H82_RS14890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C2H82_RS14895	COG1388	LysM domain
C2H82_RS14895	COG4942	peptidase
C2H82_RS14950	COG2234	aminopeptidase activity
C2H82_RS14955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2H82_RS14960	COG1518	maintenance of DNA repeat elements
C2H82_RS14975	COG1857	crispr-associated protein
C2H82_RS14990	COG1203	CRISPR-associated helicase, Cas3
C2H82_RS15010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C2H82_RS15015	COG0720	synthase
C2H82_RS15020	COG0644	oxidoreductase
C2H82_RS15025	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C2H82_RS15030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C2H82_RS15035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C2H82_RS15040	COG2086	electron transfer activity
C2H82_RS15045	COG0477	Major facilitator Superfamily
C2H82_RS15050	COG0277	FAD linked oxidase domain protein
C2H82_RS15055	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS15060	COG2223	nitrite transmembrane transporter activity
C2H82_RS15065	COG1070	Carbohydrate kinase
C2H82_RS15070	COG0602	queuosine metabolic process
C2H82_RS15080	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C2H82_RS15095	COG3956	TIGRFAM MazG family protein
C2H82_RS15100	COG2337	Toxic component of a toxin-antitoxin (TA) module
C2H82_RS15105	COG2336	PFAM SpoVT AbrB
C2H82_RS15110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C2H82_RS15115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C2H82_RS15120	COG2205	protein histidine kinase activity
C2H82_RS15120	COG3850	Histidine kinase
C2H82_RS15120	COG4999	Histidine kinase
C2H82_RS15120	COG3437	response regulator, receiver
C2H82_RS15125	COG4948	Mandelate Racemase Muconate Lactonizing
C2H82_RS15130	COG4948	Mandelate Racemase Muconate Lactonizing
C2H82_RS15135	COG2271	Major facilitator Superfamily
C2H82_RS15140	COG0716	FMN binding
C2H82_RS15145	COG0564	pseudouridine synthase activity
C2H82_RS15150	COG3098	single-species biofilm formation
C2H82_RS15165	COG1611	Belongs to the LOG family
C2H82_RS15170	COG0814	amino acid
C2H82_RS15175	COG1760	l-serine dehydratase
C2H82_RS15185	COG1454	alcohol dehydrogenase
C2H82_RS15190	COG0235	Class ii aldolase
C2H82_RS15195	COG0738	Major facilitator superfamily
C2H82_RS15205	COG1070	Carbohydrate kinase
C2H82_RS15215	COG1349	DNA-binding transcription factor activity
C2H82_RS15225	COG2363	Small membrane protein
C2H82_RS15230	COG0583	DNA-binding transcription factor activity
C2H82_RS15240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C2H82_RS15245	COG2166	iron-sulfur cluster assembly
C2H82_RS15250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C2H82_RS15255	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C2H82_RS15280	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2H82_RS15290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C2H82_RS15290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C2H82_RS15295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C2H82_RS15300	COG1074	ATP-dependent DNA helicase activity
C2H82_RS15305	COG1025	Belongs to the peptidase M16 family
C2H82_RS15310	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C2H82_RS15315	COG4967	type IV pilus modification protein PilV
C2H82_RS15325	COG4795	General secretion pathway protein
C2H82_RS15330	COG2165	general secretion pathway protein
C2H82_RS15345	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C2H82_RS15360	COG0861	Integral membrane protein TerC family
C2H82_RS15370	COG0667	Aldo Keto reductase
C2H82_RS15385	COG1609	Transcriptional regulator
C2H82_RS15395	COG0583	DNA-binding transcription factor activity
C2H82_RS15400	COG1794	racemase activity, acting on amino acids and derivatives
C2H82_RS15405	COG2814	Major facilitator Superfamily
C2H82_RS15410	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS15420	COG0183	Belongs to the thiolase family
C2H82_RS15425	COG0814	amino acid
C2H82_RS15430	COG2771	luxR family
C2H82_RS15435	COG3710	Transcriptional regulator
C2H82_RS15460	COG0457	Tetratricopeptide repeat
C2H82_RS15465	COG3710	Transcriptional regulator
C2H82_RS15465	COG0457	Tetratricopeptide repeat
C2H82_RS15480	COG2197	response regulator
C2H82_RS15485	COG2197	response regulator
C2H82_RS15515	COG3387	PFAM Glycoside hydrolase 15-related
C2H82_RS15525	COG4942	peptidase
C2H82_RS15535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C2H82_RS15540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C2H82_RS15545	COG2080	2 iron, 2 sulfur cluster binding
C2H82_RS15550	COG3829	transcription factor binding
C2H82_RS15555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C2H82_RS15560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C2H82_RS15565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2H82_RS15575	COG0549	Belongs to the carbamate kinase family
C2H82_RS15580	COG3608	succinylglutamate desuccinylase aspartoacylase
C2H82_RS15580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C2H82_RS15585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C2H82_RS15590	COG2068	MobA-Related Protein
C2H82_RS15595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS15595	COG0493	'glutamate synthase
C2H82_RS15600	COG0402	S-adenosylhomocysteine deaminase activity
C2H82_RS15605	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C2H82_RS15610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C2H82_RS15610	COG2080	2 iron, 2 sulfur cluster binding
C2H82_RS15615	COG2233	PERMEase
C2H82_RS15620	COG0402	S-adenosylhomocysteine deaminase activity
C2H82_RS15625	COG2252	PERMEase
C2H82_RS15630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS15635	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS15635	COG0493	'glutamate synthase
C2H82_RS15645	COG2233	PERMEase
C2H82_RS15660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C2H82_RS15670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C2H82_RS15675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C2H82_RS15680	COG4974	Belongs to the 'phage' integrase family
C2H82_RS15685	COG0716	FMN binding
C2H82_RS15695	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C2H82_RS15705	COG1272	protein, Hemolysin III
C2H82_RS15715	COG2723	6-phospho-beta-galactosidase activity
C2H82_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS15740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2H82_RS15745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2H82_RS15750	COG0006	proline dipeptidase activity
C2H82_RS15775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C2H82_RS15785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C2H82_RS15805	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C2H82_RS15805	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C2H82_RS15810	COG1703	isobutyryl-CoA mutase activity
C2H82_RS15815	COG1024	Enoyl-CoA hydratase
C2H82_RS15820	COG0427	acetyl-CoA hydrolase
C2H82_RS15825	COG0583	DNA-binding transcription factor activity
C2H82_RS15830	COG2968	Membrane
C2H82_RS15835	COG1279	arginine transmembrane transporter activity
C2H82_RS15840	COG0668	transmembrane transport
C2H82_RS15850	COG0191	fructose-bisphosphate aldolase activity
C2H82_RS15870	COG1072	(Pantothenic acid kinase))
C2H82_RS15875	COG3722	fumarate hydratase activity
C2H82_RS15880	COG1494	fructose-1,6-bisphosphatase
C2H82_RS15885	COG1063	alcohol dehydrogenase
C2H82_RS15890	COG2213	PTS system mannitol-specific
C2H82_RS15895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS15900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C2H82_RS15905	COG0501	Belongs to the peptidase M48B family
C2H82_RS15915	COG1166	arginine decarboxylase activity
C2H82_RS15940	COG2814	Major facilitator Superfamily
C2H82_RS15950	COG2356	endonuclease I
C2H82_RS15955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C2H82_RS15960	COG0189	ligase activity
C2H82_RS15975	COG2805	Type II/IV secretion system protein
C2H82_RS15980	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C2H82_RS15985	COG0762	integral membrane protein
C2H82_RS15995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C2H82_RS16000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2H82_RS16010	COG0252	asparaginase activity
C2H82_RS16020	COG3171	Protein conserved in bacteria
C2H82_RS16035	COG1194	a g-specific adenine glycosylase
C2H82_RS16050	COG2211	Major facilitator Superfamily
C2H82_RS16055	COG1982	Orn Lys Arg decarboxylase major
C2H82_RS16065	COG1811	Na channel or pump
C2H82_RS16075	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C2H82_RS16085	COG3031	protein transport across the cell outer membrane
C2H82_RS16095	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C2H82_RS16100	COG3064	Membrane
C2H82_RS16110	COG1620	l-lactate permease
C2H82_RS16115	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C2H82_RS16120	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C2H82_RS16125	COG0247	lactate metabolic process
C2H82_RS16130	COG0277	FAD linked oxidase domain protein
C2H82_RS16135	COG0277	FAD linked oxidase domain protein
C2H82_RS16140	COG2186	Transcriptional regulator
C2H82_RS16145	COG0456	acetyltransferase
C2H82_RS16155	COG2244	polysaccharide biosynthetic process
C2H82_RS16160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C2H82_RS16165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C2H82_RS16170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C2H82_RS16175	COG0306	phosphate transporter
C2H82_RS16180	COG0754	glutathionylspermidine amidase activity
C2H82_RS16185	COG0625	glutathione transferase activity
C2H82_RS16190	COG0298	carbon dioxide binding
C2H82_RS16200	COG1773	rubredoxin
C2H82_RS16205	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C2H82_RS16210	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C2H82_RS16215	COG5557	Pfam Polysulphide reductase, NrfD
C2H82_RS16220	COG0437	4 iron, 4 sulfur cluster binding
C2H82_RS16225	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C2H82_RS16250	COG0667	Aldo Keto reductase
C2H82_RS16260	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS16265	COG0848	biopolymer transport protein
C2H82_RS16270	COG0811	peptide transport
C2H82_RS16280	COG0626	cystathionine gamma-synthase activity
C2H82_RS16285	COG0586	Pfam SNARE associated Golgi protein
C2H82_RS16290	COG2207	Transcriptional regulator
C2H82_RS16295	COG1979	alcohol dehydrogenase
C2H82_RS16300	COG0656	L-ascorbic acid biosynthetic process
C2H82_RS16310	COG4238	major outer membrane lipoprotein
C2H82_RS16315	COG1032	radical SAM domain protein
C2H82_RS16320	COG2132	Multicopper oxidase
C2H82_RS16325	COG0204	Acyl-transferase
C2H82_RS16330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C2H82_RS16335	COG4166	transmembrane transport
C2H82_RS16345	COG2944	sequence-specific DNA binding
C2H82_RS16355	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C2H82_RS16360	COG3111	PFAM Bacterial OB fold (BOF) protein
C2H82_RS16365	COG0745	RESPONSE REGULATOR receiver
C2H82_RS16370	COG0642	Histidine kinase
C2H82_RS16385	COG2249	NAD(P)H dehydrogenase (quinone) activity
C2H82_RS16390	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C2H82_RS16395	COG0187	DNA topoisomerase II activity
C2H82_RS16400	COG3150	esterase
C2H82_RS16405	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C2H82_RS16410	COG3151	Protein conserved in bacteria
C2H82_RS16415	COG0494	nUDIX hydrolase
C2H82_RS16420	COG1538	Outer membrane efflux protein
C2H82_RS16435	COG0754	glutathionylspermidine amidase activity
C2H82_RS16440	COG3384	dioxygenase
C2H82_RS16460	COG2960	long-chain fatty acid transporting porin activity
C2H82_RS16465	COG3539	Fimbrial protein
C2H82_RS16485	COG3188	usher protein
C2H82_RS16490	COG3121	Chaperone
C2H82_RS16495	COG3539	Fimbrial protein
C2H82_RS16505	COG1585	Membrane protein implicated in regulation of membrane protease activity
C2H82_RS16510	COG2268	Band 7 protein
C2H82_RS16540	COG3025	triphosphatase activity
C2H82_RS16550	COG4991	sh3 domain protein
C2H82_RS16565	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C2H82_RS16575	COG0583	DNA-binding transcription factor activity
C2H82_RS16585	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C2H82_RS16590	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C2H82_RS16595	COG0471	metal ion transport
C2H82_RS16610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C2H82_RS16615	COG0358	DNA primase activity
C2H82_RS16625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C2H82_RS16640	COG2375	cellular response to nickel ion
C2H82_RS16645	COG1695	Transcriptional regulator
C2H82_RS16650	COG0840	transmembrane signaling receptor activity
C2H82_RS16665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2H82_RS16675	COG1609	Transcriptional regulator
C2H82_RS16680	COG3250	beta-galactosidase activity
C2H82_RS16685	COG2731	YhcH YjgK YiaL family protein
C2H82_RS16690	COG0531	amino acid
C2H82_RS16700	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C2H82_RS16700	COG3408	Glycogen debranching enzyme
C2H82_RS16705	COG1902	pentaerythritol trinitrate reductase activity
C2H82_RS16705	COG0446	pyridine nucleotide-disulphide oxidoreductase
C2H82_RS16710	COG5499	transcription regulator containing HTH domain
C2H82_RS16715	COG4680	protein conserved in bacteria
C2H82_RS16730	COG1451	nucleotide metabolic process
C2H82_RS16735	COG2949	membrane
C2H82_RS16740	COG0673	inositol 2-dehydrogenase activity
C2H82_RS16745	COG0861	Integral membrane protein TerC family
C2H82_RS16750	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C2H82_RS16760	COG2721	sulfolactate sulfo-lyase activity
C2H82_RS16770	COG2271	Major facilitator Superfamily
C2H82_RS16775	COG2186	Transcriptional regulator
C2H82_RS16780	COG0586	Pfam SNARE associated Golgi protein
C2H82_RS16790	COG1422	Protein of unknown function (DUF1090)
C2H82_RS16795	COG4575	ribosome binding
C2H82_RS16800	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C2H82_RS16810	COG2259	Doxx family
C2H82_RS16815	COG0435	Glutathione S-transferase
C2H82_RS16820	COG3152	Membrane
C2H82_RS16825	COG3152	Membrane
C2H82_RS16835	COG0583	DNA-binding transcription factor activity
C2H82_RS16840	COG1741	Belongs to the pirin family
C2H82_RS16855	COG0814	amino acid
C2H82_RS16865	COG1760	l-serine dehydratase
C2H82_RS16870	COG0251	oxidation-reduction process
C2H82_RS16875	COG1882	Formate acetyltransferase
C2H82_RS16880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C2H82_RS16890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C2H82_RS16900	COG0583	DNA-binding transcription factor activity
C2H82_RS16925	COG1929	Belongs to the glycerate kinase type-1 family
C2H82_RS16930	COG2084	Dehydrogenase
C2H82_RS16940	COG2271	Major facilitator Superfamily
C2H82_RS16945	COG2721	sulfolactate sulfo-lyase activity
C2H82_RS16950	COG2002	toxin-antitoxin pair type II binding
C2H82_RS16960	COG1349	DNA-binding transcription factor activity
C2H82_RS16975	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS16990	COG2222	sugar isomerase
C2H82_RS17000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS17005	COG3715	PTS system
C2H82_RS17010	COG3716	PTS system mannose fructose sorbose family IID component
C2H82_RS17015	COG0363	glucosamine-6-phosphate deaminase activity
C2H82_RS17020	COG3539	Fimbrial protein
C2H82_RS17025	COG3121	Chaperone
C2H82_RS17030	COG3188	usher protein
C2H82_RS17035	COG3539	Fimbrial protein
C2H82_RS17040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C2H82_RS17045	COG3107	peptidoglycan biosynthetic process
C2H82_RS17060	COG2823	Periplasmic or secreted lipoprotein
C2H82_RS17065	COG0701	Predicted permease
C2H82_RS17070	COG0702	epimerase
C2H82_RS17075	COG0693	protein deglycase activity
C2H82_RS17090	COG3153	acetyltransferase
C2H82_RS17095	COG3154	lipid carrier protein
C2H82_RS17100	COG0826	peptidase U32
C2H82_RS17105	COG0826	peptidase U32
C2H82_RS17110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2H82_RS17115	COG0814	amino acid
C2H82_RS17120	COG0513	Belongs to the DEAD box helicase family
C2H82_RS17160	COG0195	Participates in both transcription termination and antitermination
C2H82_RS17180	COG2194	sulfuric ester hydrolase activity
C2H82_RS17190	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C2H82_RS17200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C2H82_RS17205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C2H82_RS17215	COG1534	Rna-binding protein
C2H82_RS17220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C2H82_RS17225	COG2027	D-alanyl-D-alanine carboxypeptidase
C2H82_RS17235	COG0697	spore germination
C2H82_RS17250	COG0142	geranyltranstransferase activity
C2H82_RS17255	COG3423	Transcriptional regulator
C2H82_RS17265	COG5007	Belongs to the BolA IbaG family
C2H82_RS17270	COG3113	response to antibiotic
C2H82_RS17275	COG2854	intermembrane phospholipid transfer
C2H82_RS17280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C2H82_RS17285	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C2H82_RS17290	COG1127	ABC transporter
C2H82_RS17295	COG0530	calcium, potassium:sodium antiporter activity
C2H82_RS17300	COG0517	IMP dehydrogenase activity
C2H82_RS17300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C2H82_RS17305	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C2H82_RS17310	COG3117	lipopolysaccharide transmembrane transporter activity
C2H82_RS17315	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C2H82_RS17320	COG1137	ATPase activity
C2H82_RS17325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C2H82_RS17330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C2H82_RS17345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS17350	COG0515	serine threonine protein kinase
C2H82_RS17360	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C2H82_RS17365	COG5002	protein histidine kinase activity
C2H82_RS17365	COG2198	Histidine kinase
C2H82_RS17365	COG0784	Response regulator, receiver
C2H82_RS17370	COG1242	4 iron, 4 sulfur cluster binding
C2H82_RS17385	COG0070	glutamate synthase
C2H82_RS17385	COG0069	glutamate synthase activity
C2H82_RS17385	COG0067	glutamate synthase
C2H82_RS17390	COG0493	'glutamate synthase
C2H82_RS17400	COG3539	Fimbrial protein
C2H82_RS17405	COG3121	Chaperone
C2H82_RS17410	COG3188	usher protein
C2H82_RS17430	COG3539	Fimbrial protein
C2H82_RS17435	COG4804	nuclease activity
C2H82_RS17440	COG2731	YhcH YjgK YiaL family protein
C2H82_RS17475	COG3069	C4-dicarboxylate transmembrane transporter activity
C2H82_RS17480	COG2969	positive regulation of protein catabolic process
C2H82_RS17485	COG0625	glutathione transferase activity
C2H82_RS17505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C2H82_RS17510	COG3105	Protein conserved in bacteria
C2H82_RS17515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2H82_RS17520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2H82_RS17540	COG2732	(Barnase) inhibitor
C2H82_RS17545	COG1289	transmembrane transporter activity
C2H82_RS17560	COG0583	DNA-binding transcription factor activity
C2H82_RS17565	COG0312	modulator of DNA gyrase
C2H82_RS17570	COG3164	Protein of unknown function
C2H82_RS17575	COG1530	ribonuclease E activity
C2H82_RS17580	COG0424	maF-like protein
C2H82_RS17585	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C2H82_RS17590	COG1792	Involved in formation and maintenance of cell shape
C2H82_RS17595	COG1077	Cell shape determining protein MreB Mrl
C2H82_RS17610	COG2199	diguanylate cyclase activity
C2H82_RS17610	COG2200	EAL domain
C2H82_RS17615	COG0604	alcohol dehydrogenase
C2H82_RS17625	COG0511	ligase activity, forming carbon-carbon bonds
C2H82_RS17630	COG0439	Biotin carboxylase
C2H82_RS17635	COG3924	membrane
C2H82_RS17640	COG4145	pantothenate transmembrane transporter activity
C2H82_RS17650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2H82_RS17660	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C2H82_RS17670	COG1309	transcriptional regulator
C2H82_RS17680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2H82_RS17685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2H82_RS17705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H82_RS17710	COG4597	amino acid ABC transporter
C2H82_RS17715	COG0765	amino acid transport
C2H82_RS17720	COG1126	abc transporter atp-binding protein
C2H82_RS17760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C2H82_RS17780	COG0551	DNA topoisomerase type I activity
C2H82_RS17790	COG0758	DNA mediated transformation
C2H82_RS17810	COG0569	domain protein
C2H82_RS17820	COG3036	rescue of stalled ribosome
C2H82_RS17825	COG0789	Transcriptional regulator
C2H82_RS17865	COG0201	protein transport
C2H82_RS17955	COG0089	rRNA binding
C2H82_RS17980	COG3409	Peptidoglycan-binding domain 1 protein
C2H82_RS17980	COG3267	Type II secretory pathway component ExeA
C2H82_RS17985	COG3031	protein transport across the cell outer membrane
C2H82_RS17990	COG1450	Type ii and iii secretion system protein
C2H82_RS17995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C2H82_RS18000	COG1459	type II secretion system
C2H82_RS18005	COG2165	general secretion pathway protein
C2H82_RS18010	COG2165	general secretion pathway protein
C2H82_RS18015	COG2165	general secretion pathway protein
C2H82_RS18020	COG4795	General secretion pathway protein
C2H82_RS18025	COG3156	type II secretion system protein K
C2H82_RS18030	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C2H82_RS18035	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C2H82_RS18040	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C2H82_RS18045	COG2193	ferroxidase activity
C2H82_RS18050	COG2906	2 iron, 2 sulfur cluster binding
C2H82_RS18055	COG3979	chitinase
C2H82_RS18100	COG2964	Protein conserved in bacteria
C2H82_RS18105	COG0545	Peptidyl-prolyl cis-trans isomerase
C2H82_RS18115	COG1047	Peptidyl-prolyl cis-trans
C2H82_RS18120	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C2H82_RS18140	COG0488	(ABC) transporter
C2H82_RS18145	COG0429	hydrolase of the alpha beta-hydrolase fold
C2H82_RS18155	COG3954	Phosphoribulokinase
C2H82_RS18160	COG1765	OsmC-like protein
C2H82_RS18170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2H82_RS18175	COG1289	transmembrane transporter activity
C2H82_RS18180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C2H82_RS18185	COG0512	Glutamine amidotransferase of anthranilate synthase
C2H82_RS18190	COG2184	nucleotidyltransferase activity
C2H82_RS18200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C2H82_RS18210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C2H82_RS18215	COG2146	nitrite reductase [NAD(P)H] activity
C2H82_RS18220	COG2116	formate transmembrane transporter activity
C2H82_RS18235	COG0531	amino acid
C2H82_RS18240	COG2222	sugar isomerase
C2H82_RS18250	COG1082	Xylose isomerase domain protein TIM barrel
C2H82_RS18255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H82_RS18260	COG2188	Transcriptional regulator
C2H82_RS18265	COG0626	cystathionine gamma-synthase activity
C2H82_RS18280	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C2H82_RS18285	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C2H82_RS18290	COG3457	Alanine racemase
C2H82_RS18300	COG2188	Transcriptional regulator
C2H82_RS18310	COG0180	Tryptophanyl-tRNA synthetase
C2H82_RS18315	COG0546	phosphoglycolate phosphatase activity
C2H82_RS18320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2H82_RS18325	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C2H82_RS18330	COG3266	domain, Protein
C2H82_RS18345	COG4796	Type ii and iii secretion system protein
C2H82_RS18360	COG3166	PFAM Fimbrial assembly family protein
C2H82_RS18365	COG4972	Pilus assembly protein
C2H82_RS18370	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C2H82_RS18375	COG0494	nUDIX hydrolase
C2H82_RS18385	COG1011	Hydrolase
C2H82_RS18390	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C2H82_RS18400	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C2H82_RS18430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C2H82_RS18435	COG2183	response to ionizing radiation
C2H82_RS18445	COG1918	ferrous iron import across plasma membrane
C2H82_RS18450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C2H82_RS18465	COG5464	transposase or invertase
C2H82_RS18475	COG1040	competence protein
C2H82_RS18485	COG2610	gluconate transmembrane transporter activity
C2H82_RS18490	COG1640	4-alpha-glucanotransferase
C2H82_RS18495	COG0058	SHG alpha-glucan phosphorylase activity
C2H82_RS18510	COG1690	Belongs to the RtcB family
C2H82_RS18515	COG4650	regulator
C2H82_RS18520	COG1349	DNA-binding transcription factor activity
C2H82_RS18535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C2H82_RS18540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C2H82_RS18545	COG0058	SHG alpha-glucan phosphorylase activity
C2H82_RS18570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C2H82_RS18575	COG2095	MarC family integral membrane protein
C2H82_RS18580	COG2610	gluconate transmembrane transporter activity
C2H82_RS18585	COG3265	gluconokinase activity
C2H82_RS18590	COG1609	Transcriptional regulator
C2H82_RS18595	COG1741	Belongs to the pirin family
C2H82_RS18600	COG0673	inositol 2-dehydrogenase activity
C2H82_RS18610	COG1247	-acetyltransferase
C2H82_RS18615	COG3157	Type VI secretion system effector, Hcp
C2H82_RS18640	COG0405	Gamma-glutamyltransferase
C2H82_RS18650	COG0584	glycerophosphoryl diester phosphodiesterase
C2H82_RS18655	COG3842	ATPase activity
C2H82_RS18660	COG0395	ABC-type sugar transport system, permease component
C2H82_RS18665	COG1175	transmembrane transport
C2H82_RS18670	COG1653	transport
C2H82_RS18675	COG0410	ABC transporter
C2H82_RS18680	COG0411	ABC transporter
C2H82_RS18685	COG4177	L-phenylalanine transmembrane transporter activity
C2H82_RS18690	COG0559	Belongs to the binding-protein-dependent transport system permease family
C2H82_RS18695	COG0683	leucine binding
C2H82_RS18700	COG0456	acetyltransferase
C2H82_RS18705	COG0683	leucine binding
C2H82_RS18710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C2H82_RS18715	COG2177	Part of the ABC transporter FtsEX involved in
C2H82_RS18720	COG2884	Cell division ATP-binding protein ftsE
C2H82_RS18725	COG0552	protein localization to endoplasmic reticulum
C2H82_RS18730	COG0742	ribosomal rna small subunit methyltransferase
C2H82_RS18735	COG3776	membrane
C2H82_RS18745	COG3714	YhhN family
C2H82_RS18750	COG2217	Heavy metal translocating P-type atpase
C2H82_RS18760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C2H82_RS18770	COG0477	Major facilitator Superfamily
C2H82_RS18775	COG0628	permease
C2H82_RS18780	COG2091	lysine biosynthetic process via aminoadipic acid
C2H82_RS18785	COG0747	negative chemotaxis
C2H82_RS18790	COG0601	transmembrane transport
C2H82_RS18795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2H82_RS18800	COG0444	Belongs to the ABC transporter superfamily
C2H82_RS18805	COG1124	(ABC) transporter
C2H82_RS18815	COG3209	COG3209 Rhs family protein
C2H82_RS18825	COG1413	lyase activity
C2H82_RS18830	COG5433	transposase activity
C2H82_RS18835	COG0842	Transport permease protein
C2H82_RS18840	COG1129	ABC transporter
C2H82_RS18840	COG0842	Transport permease protein
C2H82_RS18845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2H82_RS18870	COG2081	HI0933 family
C2H82_RS18875	COG0306	phosphate transporter
C2H82_RS18885	COG0589	response to stress
C2H82_RS18895	COG3104	oligopeptide transport
C2H82_RS18905	COG0339	signal peptide processing
C2H82_RS18910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C2H82_RS18915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2H82_RS18930	COG0640	Transcriptional regulator
C2H82_RS18935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2H82_RS18940	COG1393	Belongs to the ArsC family
C2H82_RS18960	COG3065	identical protein binding
C2H82_RS18970	COG2197	response regulator
C2H82_RS18975	COG1285	pathogenesis
C2H82_RS18990	COG3247	response to pH
C2H82_RS18995	COG2771	luxR family
C2H82_RS19005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2H82_RS19010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2H82_RS19020	COG2207	Transcriptional regulator
C2H82_RS19025	COG2207	Transcriptional regulator
C2H82_RS19030	COG0076	glutamate decarboxylase activity
C2H82_RS19035	COG1858	cytochrome C peroxidase
C2H82_RS19045	COG2197	response regulator
C2H82_RS19050	COG0583	DNA-binding transcription factor activity
C2H82_RS19055	COG1295	ribonuclease BN
C2H82_RS19060	COG0477	Major facilitator Superfamily
C2H82_RS19065	COG2982	Protein involved in outer membrane biogenesis
C2H82_RS19070	COG2200	EAL domain
C2H82_RS19080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H82_RS19085	COG0612	Peptidase, M16
C2H82_RS19100	COG2200	EAL domain
C2H82_RS19100	COG2199	diguanylate cyclase activity
C2H82_RS19105	COG0457	Tetratricopeptide repeat
C2H82_RS19105	COG3118	belongs to the thioredoxin family
C2H82_RS19110	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C2H82_RS19115	COG1215	transferase activity, transferring glycosyl groups
C2H82_RS19120	COG1215	transferase activity, transferring glycosyl groups
C2H82_RS19145	COG2194	sulfuric ester hydrolase activity
C2H82_RS19165	COG0814	amino acid
C2H82_RS19170	COG4608	Belongs to the ABC transporter superfamily
C2H82_RS19175	COG0444	Belongs to the ABC transporter superfamily
C2H82_RS19180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2H82_RS19185	COG0601	transmembrane transport
C2H82_RS19190	COG0747	negative chemotaxis
C2H82_RS19210	COG2194	sulfuric ester hydrolase activity
C2H82_RS19215	COG2223	nitrite transmembrane transporter activity
C2H82_RS19225	COG5571	outer membrane autotransporter
C2H82_RS19230	COG2818	Glycosylase
C2H82_RS19235	COG0456	acetyltransferase
C2H82_RS19240	COG0243	molybdopterin cofactor binding
C2H82_RS19245	COG2885	chlorophyll binding
C2H82_RS19260	COG2944	sequence-specific DNA binding
C2H82_RS19265	COG1278	Cold shock
C2H82_RS19285	COG0752	glycyl-tRNA synthetase alpha subunit
C2H82_RS19295	COG3274	enterobacterial common antigen metabolic process
C2H82_RS19300	COG4682	membrane
C2H82_RS19305	COG4682	membrane
C2H82_RS19310	COG1070	Carbohydrate kinase
C2H82_RS19320	COG4213	ABC transporter substrate-binding protein
C2H82_RS19325	COG1129	ABC transporter
C2H82_RS19330	COG4214	carbohydrate transport
C2H82_RS19335	COG2207	Transcriptional regulator
C2H82_RS19335	COG1609	Transcriptional regulator
C2H82_RS19340	COG2992	FlgJ-related protein
C2H82_RS19345	COG0366	Alpha amylase catalytic
C2H82_RS19350	COG3977	Valine--pyruvate aminotransferase
C2H82_RS19355	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2H82_RS19360	COG1414	Transcriptional regulator
C2H82_RS19370	COG2731	YhcH YjgK YiaL family protein
C2H82_RS19375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C2H82_RS19380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C2H82_RS19385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C2H82_RS19390	COG1070	Carbohydrate kinase
C2H82_RS19395	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C2H82_RS19400	COG3623	hexulose-6-phosphate isomerase
C2H82_RS19405	COG0235	Class ii aldolase
C2H82_RS19415	COG3713	MltA-interacting MipA family protein
C2H82_RS19420	COG0583	DNA-binding transcription factor activity
C2H82_RS19425	COG1566	PFAM secretion protein HlyD family protein
C2H82_RS19440	COG1012	belongs to the aldehyde dehydrogenase family
C2H82_RS19445	COG1454	alcohol dehydrogenase
C2H82_RS19450	COG3276	selenocysteine insertion sequence binding
C2H82_RS19460	COG0625	glutathione transferase activity
C2H82_RS19465	COG3209	COG3209 Rhs family protein
C2H82_RS19470	COG1413	lyase activity
C2H82_RS19480	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C2H82_RS19500	COG1566	PFAM secretion protein HlyD family protein
C2H82_RS19510	COG2213	PTS system mannitol-specific
C2H82_RS19510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS19520	COG3722	fumarate hydratase activity
C2H82_RS19540	COG1620	l-lactate permease
C2H82_RS19545	COG2186	Transcriptional regulator
C2H82_RS19555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C2H82_RS19560	COG1045	serine acetyltransferase
C2H82_RS19575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C2H82_RS19580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2H82_RS19590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C2H82_RS19595	COG4942	peptidase
C2H82_RS19600	COG2861	carbohydrate metabolic process
C2H82_RS19605	COG1216	Glycosyl transferase, family 2
C2H82_RS19615	COG0156	8-amino-7-oxononanoate synthase activity
C2H82_RS19630	COG0859	PFAM glycosyl transferase family 9
C2H82_RS19635	COG0859	PFAM glycosyl transferase family 9
C2H82_RS19640	COG3307	-O-antigen
C2H82_RS19645	COG0859	PFAM glycosyl transferase family 9
C2H82_RS19655	COG3642	lipopolysaccharide core region biosynthetic process
C2H82_RS19660	COG1442	glycosyl transferase family 8
C2H82_RS19665	COG1442	glycosyl transferase family 8
C2H82_RS19670	COG0438	transferase activity, transferring glycosyl groups
C2H82_RS19675	COG4641	Protein conserved in bacteria
C2H82_RS19675	COG0438	transferase activity, transferring glycosyl groups
C2H82_RS19680	COG0515	serine threonine protein kinase
C2H82_RS19685	COG0438	transferase activity, transferring glycosyl groups
C2H82_RS19690	COG0859	PFAM glycosyl transferase family 9
C2H82_RS19695	COG1519	Transferase
C2H82_RS19725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C2H82_RS19755	COG1561	YicC-like family, N-terminal region
C2H82_RS19760	COG3645	SOS response
C2H82_RS19765	COG2860	membrane
C2H82_RS19775	COG0194	GDP metabolic process
C2H82_RS19785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C2H82_RS19790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2H82_RS19795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C2H82_RS19800	COG0786	glutamate:sodium symporter activity
C2H82_RS19805	COG2233	PERMEase
C2H82_RS19810	COG2982	Protein involved in outer membrane biogenesis
C2H82_RS19815	COG1501	Belongs to the glycosyl hydrolase 31 family
C2H82_RS19820	COG2211	Major facilitator Superfamily
C2H82_RS19835	COG2814	Major facilitator Superfamily
C2H82_RS19840	COG0697	spore germination
C2H82_RS19845	COG1464	Belongs to the NlpA lipoprotein family
C2H82_RS19875	COG2252	PERMEase
C2H82_RS19885	COG2271	Major facilitator Superfamily
C2H82_RS19890	COG2271	Major facilitator Superfamily
C2H82_RS19895	COG3851	Histidine kinase
C2H82_RS19900	COG2197	response regulator
C2H82_RS19905	COG0440	acetolactate synthase activity
C2H82_RS19910	COG0028	Belongs to the TPP enzyme family
C2H82_RS19945	COG2814	Major facilitator Superfamily
C2H82_RS19950	COG0641	radical SAM
C2H82_RS19960	COG2149	membrane
C2H82_RS19970	COG3119	arylsulfatase activity
C2H82_RS19975	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2H82_RS19980	COG2207	Transcriptional regulator
C2H82_RS19995	COG2188	Transcriptional regulator
C2H82_RS20015	COG5645	(Lipo)protein
C2H82_RS20020	COG0823	Involved in the tonB-independent uptake of proteins
C2H82_RS20025	COG0644	oxidoreductase
C2H82_RS20030	COG2271	Major facilitator Superfamily
C2H82_RS20040	COG0800	Aldolase
C2H82_RS20045	COG3734	2-keto-3-deoxy-galactonokinase
C2H82_RS20050	COG2186	Transcriptional regulator
C2H82_RS20060	COG0561	phosphatase activity
C2H82_RS20065	COG3753	Protein conserved in bacteria
C2H82_RS20070	COG0187	DNA topoisomerase II activity
C2H82_RS20080	COG0592	DNA-directed DNA polymerase activity
C2H82_RS20130	COG0814	amino acid
C2H82_RS20145	COG2091	lysine biosynthetic process via aminoadipic acid
C2H82_RS20150	COG0431	NADPH-dependent FMN reductase
C2H82_RS20155	COG2252	PERMEase
C2H82_RS20160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2H82_RS20170	COG3196	Protein conserved in bacteria
C2H82_RS20175	COG0363	glucosamine-6-phosphate deaminase activity
C2H82_RS20180	COG2382	esterase
C2H82_RS20190	COG2723	6-phospho-beta-galactosidase activity
C2H82_RS20195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS20195	COG1263	PTS System
C2H82_RS20195	COG2190	(PTS) system
C2H82_RS20200	COG3711	transcriptional antiterminator
C2H82_RS20205	COG0704	Plays a role in the regulation of phosphate uptake
C2H82_RS20210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C2H82_RS20215	COG0581	inorganic phosphate transmembrane transporter activity
C2H82_RS20220	COG0573	inorganic phosphate transmembrane transporter activity
C2H82_RS20225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C2H82_RS20230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C2H82_RS20280	COG3312	ion transport
C2H82_RS20295	COG0716	FMN binding
C2H82_RS20300	COG1522	sequence-specific DNA binding
C2H82_RS20330	COG1129	ABC transporter
C2H82_RS20335	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2H82_RS20340	COG1879	ABC-type sugar transport system periplasmic component
C2H82_RS20345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H82_RS20350	COG1609	Transcriptional regulator
C2H82_RS20355	COG0477	Major facilitator Superfamily
C2H82_RS20360	COG2186	Transcriptional regulator
C2H82_RS20400	COG3085	chromosome segregation
C2H82_RS20405	COG0606	chelatase, subunit chli
C2H82_RS20430	COG3978	acetolactate synthase activity
C2H82_RS20435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2H82_RS20445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C2H82_RS20450	COG0583	DNA-binding transcription factor activity
C2H82_RS20460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2H82_RS20470	COG0210	DNA helicase
C2H82_RS20490	COG3118	belongs to the thioredoxin family
C2H82_RS20500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C2H82_RS20510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C2H82_RS20515	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C2H82_RS20520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C2H82_RS20525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C2H82_RS20530	COG1088	dTDP-glucose 4,6-dehydratase activity
C2H82_RS20535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C2H82_RS20540	COG0456	acetyltransferase
C2H82_RS20545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C2H82_RS20550	COG2244	polysaccharide biosynthetic process
C2H82_RS20570	COG1113	amino acid transport
C2H82_RS20595	COG0641	radical SAM
C2H82_RS20600	COG3119	arylsulfatase activity
C2H82_RS20605	COG3071	HemY protein
C2H82_RS20610	COG2959	enzyme of heme biosynthesis
C2H82_RS20615	COG1587	Uroporphyrinogen-III synthase
C2H82_RS20630	COG3072	Adenylate cyclase
C2H82_RS20640	COG5567	small periplasmic lipoprotein
C2H82_RS20650	COG3159	Protein conserved in bacteria
C2H82_RS20660	COG1011	Hydrolase
C2H82_RS20665	COG0210	DNA helicase
C2H82_RS20670	COG3698	Phosphodiester glycosidase
C2H82_RS20675	COG0598	Magnesium transport protein CorA
C2H82_RS20690	COG2962	Rard protein
C2H82_RS20695	COG2050	protein possibly involved in aromatic compounds catabolism
C2H82_RS20700	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C2H82_RS20705	COG0514	ATP-dependent DNA helicase (RecQ)
C2H82_RS20710	COG1280	lysine exporter protein (LysE YggA)
C2H82_RS20715	COG1280	lysine exporter protein (LysE YggA)
C2H82_RS20720	COG2267	carboxylic ester hydrolase activity
C2H82_RS20725	COG0561	phosphatase activity
C2H82_RS20730	COG0697	spore germination
C2H82_RS20735	COG0583	DNA-binding transcription factor activity
C2H82_RS20745	COG0412	Dienelactone hydrolase
C2H82_RS20750	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C2H82_RS20760	COG1322	Protein conserved in bacteria
C2H82_RS20770	COG3165	ubiquinone biosynthetic process from chorismate
C2H82_RS20780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C2H82_RS20785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C2H82_RS20790	COG0805	protein transport
C2H82_RS20795	COG0084	hydrolase, TatD family'
C2H82_RS20800	COG0250	Participates in transcription elongation, termination and antitermination
C2H82_RS20805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C2H82_RS20810	COG0543	2 iron, 2 sulfur cluster binding
C2H82_RS20815	COG0183	Belongs to the thiolase family
C2H82_RS20830	COG1739	Uncharacterized protein family UPF0029
C2H82_RS20835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C2H82_RS20840	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C2H82_RS20870	COG1763	Mo-molybdopterin cofactor biosynthetic process
C2H82_RS20875	COG0746	molybdenum cofactor guanylyltransferase activity
C2H82_RS20880	COG3084	Protein conserved in bacteria
C2H82_RS20885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C2H82_RS20890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C2H82_RS20895	COG5339	Protein conserved in bacteria
C2H82_RS20900	COG0204	Acyl-transferase
C2H82_RS20910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C2H82_RS20910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C2H82_RS20925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2H82_RS20935	COG2204	response regulator
C2H82_RS20940	COG3852	Histidine kinase
C2H82_RS20945	COG0174	glutamine synthetase
C2H82_RS20955	COG1217	gtp-binding protein TYPA
C2H82_RS20960	COG2188	Transcriptional regulator
C2H82_RS20965	COG1082	Xylose isomerase domain protein TIM barrel
C2H82_RS20970	COG2271	Major facilitator Superfamily
C2H82_RS20975	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C2H82_RS20980	COG2211	Major facilitator Superfamily
C2H82_RS20985	COG2211	Major facilitator Superfamily
C2H82_RS20990	COG1501	Belongs to the glycosyl hydrolase 31 family
C2H82_RS20995	COG2017	converts alpha-aldose to the beta-anomer
C2H82_RS21000	COG2942	2-epimerase
C2H82_RS21005	COG3684	Belongs to the aldolase LacD family
C2H82_RS21010	COG2084	Dehydrogenase
C2H82_RS21015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H82_RS21020	COG1349	DNA-binding transcription factor activity
C2H82_RS21025	COG1011	Hydrolase
C2H82_RS21040	COG0456	acetyltransferase
C2H82_RS21045	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C2H82_RS21050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C2H82_RS21060	COG2864	formate dehydrogenase
C2H82_RS21065	COG0437	4 iron, 4 sulfur cluster binding
C2H82_RS21090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS21090	COG3711	transcriptional antiterminator
C2H82_RS21095	COG1363	Peptidase, m42
C2H82_RS21100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS21100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS21105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS21145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C2H82_RS21160	COG2258	MOSC domain
C2H82_RS21165	COG2205	protein histidine kinase activity
C2H82_RS21170	COG0745	RESPONSE REGULATOR receiver
C2H82_RS21175	COG3678	ATP-independent chaperone mediated protein folding
C2H82_RS21190	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C2H82_RS21210	COG3152	Membrane
C2H82_RS21215	COG3691	Protein conserved in bacteria
C2H82_RS21220	COG0589	response to stress
C2H82_RS21225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2H82_RS21230	COG1494	fructose-1,6-bisphosphatase
C2H82_RS21240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C2H82_RS21255	COG1575	Belongs to the MenA family. Type 1 subfamily
C2H82_RS21270	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C2H82_RS21275	COG1609	Transcriptional regulator
C2H82_RS21280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C2H82_RS21290	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C2H82_RS21300	COG0626	cystathionine gamma-synthase activity
C2H82_RS21305	COG0460	homoserine dehydrogenase
C2H82_RS21305	COG0527	aspartate kinase activity
C2H82_RS21310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C2H82_RS21320	COG0697	spore germination
C2H82_RS21325	COG3738	Protein conserved in bacteria
C2H82_RS21330	COG0371	Dehydrogenase
C2H82_RS21335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C2H82_RS21340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2H82_RS21340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS21340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS21345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS21350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS21355	COG1882	Formate acetyltransferase
C2H82_RS21360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2H82_RS21365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2H82_RS21370	COG2207	Transcriptional regulator
C2H82_RS21375	COG2194	sulfuric ester hydrolase activity
C2H82_RS21395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C2H82_RS21410	COG0583	DNA-binding transcription factor activity
C2H82_RS21440	COG4206	TonB-dependent receptor
C2H82_RS21470	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C2H82_RS21475	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C2H82_RS21475	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C2H82_RS21520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C2H82_RS21525	COG0250	Participates in transcription elongation, termination and antitermination
C2H82_RS21570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C2H82_RS21580	COG2104	thiamine diphosphate biosynthetic process
C2H82_RS21585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2H82_RS21620	COG3068	Protein conserved in bacteria
C2H82_RS21635	COG3678	ATP-independent chaperone mediated protein folding
C2H82_RS21645	COG4191	Histidine kinase
C2H82_RS21650	COG2204	response regulator
C2H82_RS21655	COG0151	Belongs to the GarS family
C2H82_RS21695	COG0456	acetyltransferase
C2H82_RS21705	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C2H82_RS21710	COG2224	Isocitrate lyase
C2H82_RS21725	COG1414	Transcriptional regulator
C2H82_RS21730	COG1410	methionine synthase
C2H82_RS21730	COG0646	methionine synthase
C2H82_RS21735	COG1283	sodium-dependent phosphate transmembrane transporter activity
C2H82_RS21745	COG1187	pseudouridine synthase activity
C2H82_RS21755	COG0527	aspartate kinase activity
C2H82_RS21790	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2H82_RS21805	COG0477	Major facilitator Superfamily
C2H82_RS21805	COG2814	Major facilitator Superfamily
C2H82_RS21810	COG3833	ABC-type maltose transport systems, permease component
C2H82_RS21815	COG1175	transmembrane transport
C2H82_RS21820	COG2182	Extracellular solute-binding protein
C2H82_RS21830	COG3842	ATPase activity
C2H82_RS21850	COG1357	PFAM Pentapeptide repeats (8 copies)
C2H82_RS21875	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C2H82_RS21885	COG0534	Mate efflux family protein
C2H82_RS21890	COG3237	CsbD-like
C2H82_RS21895	COG0735	belongs to the Fur family
C2H82_RS21910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2H82_RS21920	COG0604	alcohol dehydrogenase
C2H82_RS21925	COG0305	Participates in initiation and elongation during chromosome replication
C2H82_RS21930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C2H82_RS21935	COG1448	Aminotransferase
C2H82_RS21945	COG3700	Belongs to the class B bacterial acid phosphatase family
C2H82_RS21950	COG0432	Pfam Uncharacterised protein family UPF0047
C2H82_RS21955	COG2315	Protein conserved in bacteria
C2H82_RS21960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C2H82_RS21965	COG0629	single-stranded DNA binding
C2H82_RS21980	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C2H82_RS21985	COG2207	Transcriptional regulator
C2H82_RS21990	COG0789	Transcriptional regulator
C2H82_RS22010	COG2252	PERMEase
C2H82_RS22015	COG0025	NhaP-type Na H and K H
C2H82_RS22020	COG1357	PFAM Pentapeptide repeats (8 copies)
C2H82_RS22030	COG3162	membrane
C2H82_RS22035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C2H82_RS22050	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C2H82_RS22055	COG0437	4 iron, 4 sulfur cluster binding
C2H82_RS22060	COG3301	Polysulphide reductase, NrfD
C2H82_RS22065	COG1138	Cytochrome C-type biogenesis protein
C2H82_RS22070	COG3088	subunit of a heme lyase
C2H82_RS22075	COG4235	cytochrome complex assembly
C2H82_RS22085	COG1301	dicarboxylic acid transport
C2H82_RS22090	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C2H82_RS22100	COG1538	Outer membrane efflux protein
C2H82_RS22105	COG1289	transmembrane transporter activity
C2H82_RS22110	COG1566	PFAM secretion protein HlyD family protein
C2H82_RS22120	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C2H82_RS22125	COG1940	carbohydrate kinase activity
C2H82_RS22130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2H82_RS22135	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2H82_RS22140	COG1129	ABC transporter
C2H82_RS22145	COG1879	ABC-type sugar transport system periplasmic component
C2H82_RS22150	COG1737	Transcriptional regulator
C2H82_RS22160	COG0698	ribose 5-phosphate isomerase
C2H82_RS22170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C2H82_RS22175	COG0456	acetyltransferase
C2H82_RS22180	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C2H82_RS22185	COG3454	Phosphonate metabolism
C2H82_RS22190	COG4778	phosphonate C-P lyase system protein PhnL
C2H82_RS22195	COG4107	phosphonate C-P lyase system protein PhnK
C2H82_RS22200	COG3627	carbon phosphorus lyase activity
C2H82_RS22205	COG3626	phosphonate metabolism
C2H82_RS22210	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C2H82_RS22215	COG3624	Phosphonate C-P lyase system protein PhnG
C2H82_RS22220	COG2188	Transcriptional regulator
C2H82_RS22230	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C2H82_RS22235	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C2H82_RS22240	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C2H82_RS22245	COG2824	Alkylphosphonate utilization operon protein PhnA
C2H82_RS22255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C2H82_RS22265	COG0477	Major facilitator Superfamily
C2H82_RS22275	COG0642	Histidine kinase
C2H82_RS22280	COG0745	RESPONSE REGULATOR receiver
C2H82_RS22285	COG2194	sulfuric ester hydrolase activity
C2H82_RS22290	COG0531	amino acid
C2H82_RS22295	COG2207	Transcriptional regulator
C2H82_RS22300	COG1982	Orn Lys Arg decarboxylase major
C2H82_RS22305	COG2169	Transcriptional regulator
C2H82_RS22310	COG1486	melibiose metabolic process
C2H82_RS22315	COG2211	Major facilitator Superfamily
C2H82_RS22320	COG3647	Membrane
C2H82_RS22325	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C2H82_RS22325	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C2H82_RS22330	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2H82_RS22340	COG4565	transcriptional regulatory protein
C2H82_RS22345	COG3290	protein histidine kinase activity
C2H82_RS22350	COG3592	Divergent 4Fe-4S mono-cluster
C2H82_RS22355	COG2388	GCN5-related N-acetyl-transferase
C2H82_RS22375	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C2H82_RS22380	COG3104	oligopeptide transport
C2H82_RS22385	COG1982	Orn Lys Arg decarboxylase major
C2H82_RS22390	COG0531	amino acid
C2H82_RS22395	COG3710	Transcriptional regulator
C2H82_RS22410	COG1309	transcriptional regulator
C2H82_RS22415	COG4232	protein-disulfide reductase activity
C2H82_RS22425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2H82_RS22430	COG1027	Aspartate ammonia-lyase
C2H82_RS22435	COG3030	protein affecting phage T7 exclusion by the F plasmid
C2H82_RS22440	COG0531	amino acid
C2H82_RS22465	COG1509	lysine 2,3-aminomutase activity
C2H82_RS22475	COG5510	response to toxic substance
C2H82_RS22480	COG5510	response to toxic substance
C2H82_RS22485	COG2076	Multidrug Resistance protein
C2H82_RS22490	COG3040	lipid binding
C2H82_RS22495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C2H82_RS22510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C2H82_RS22515	COG1053	succinate dehydrogenase
C2H82_RS22525	COG0531	amino acid
C2H82_RS22540	COG3264	Mechanosensitive ion channel
C2H82_RS22540	COG1511	domain protein
C2H82_RS22580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C2H82_RS22585	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C2H82_RS22585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C2H82_RS22590	COG0802	atpase or kinase
C2H82_RS22595	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2H82_RS22615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C2H82_RS22620	COG0330	HflC and HflK could
C2H82_RS22625	COG0330	HflC and HflK could
C2H82_RS22630	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C2H82_RS22645	COG0557	exoribonuclease II activity
C2H82_RS22650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2H82_RS22660	COG3789	protein conserved in bacteria
C2H82_RS22665	COG1842	Phage shock protein A
C2H82_RS22675	COG3766	membrane
C2H82_RS22680	COG5463	Belongs to the UPF0441 family
C2H82_RS22685	COG0754	glutathionylspermidine amidase activity
C2H82_RS22690	COG1960	acyl-CoA dehydrogenase activity
C2H82_RS22705	COG3650	response to hydrogen peroxide
C2H82_RS22710	COG1073	alpha beta
C2H82_RS22725	COG3037	sugar-specific permease SgaT UlaA
C2H82_RS22730	COG3414	Phosphotransferase system galactitol-specific IIB component
C2H82_RS22735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS22770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C2H82_RS22790	COG1309	transcriptional regulator
C2H82_RS22795	COG3061	Opacity-associated protein A
C2H82_RS22805	COG0545	Peptidyl-prolyl cis-trans isomerase
C2H82_RS22810	COG1113	amino acid transport
C2H82_RS22820	COG0697	spore germination
C2H82_RS22825	COG0702	epimerase
C2H82_RS22830	COG1733	regulation of RNA biosynthetic process
C2H82_RS22835	COG0737	Belongs to the 5'-nucleotidase family
C2H82_RS22840	COG1218	3'(2'),5'-bisphosphate nucleotidase
C2H82_RS22855	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C2H82_RS22865	COG1253	flavin adenine dinucleotide binding
C2H82_RS22880	COG0729	surface antigen
C2H82_RS22885	COG2911	Protein conserved in bacteria
C2H82_RS22890	COG2105	PFAM AIG2 family protein
C2H82_RS22895	COG2336	PFAM SpoVT AbrB
C2H82_RS22900	COG2337	Toxic component of a toxin-antitoxin (TA) module
C2H82_RS22905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C2H82_RS22910	COG1879	ABC-type sugar transport system periplasmic component
C2H82_RS22915	COG1129	ABC transporter
C2H82_RS22920	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2H82_RS22925	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2H82_RS22935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C2H82_RS22945	COG0312	modulator of DNA gyrase
C2H82_RS22950	COG3783	Cytochrome b(562)
C2H82_RS22955	COG0602	queuosine metabolic process
C2H82_RS22960	COG1328	CTP reductase activity
C2H82_RS22965	COG0366	Alpha amylase catalytic
C2H82_RS22970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H82_RS22970	COG1263	PTS System
C2H82_RS22975	COG1609	Transcriptional regulator
C2H82_RS22985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C2H82_RS22990	COG0251	oxidation-reduction process
C2H82_RS23015	COG0251	oxidation-reduction process
C2H82_RS23020	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS23025	COG1309	transcriptional regulator
C2H82_RS23030	COG2731	YhcH YjgK YiaL family protein
C2H82_RS23040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C2H82_RS23045	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C2H82_RS23050	COG0456	acetyltransferase
C2H82_RS23055	COG4269	membrane
C2H82_RS23060	COG0525	valine-tRNA ligase activity
C2H82_RS23065	COG2927	DNA polymerase III (CHI subunit)
C2H82_RS23075	COG0795	lipopolysaccharide-transporting ATPase activity
C2H82_RS23080	COG0795	lipopolysaccharide-transporting ATPase activity
C2H82_RS23085	COG0433	COG0433 Predicted ATPase
C2H82_RS23090	COG1609	Transcriptional regulator
C2H82_RS23095	COG2610	gluconate transmembrane transporter activity
C2H82_RS23100	COG1028	Short-chain dehydrogenase reductase Sdr
C2H82_RS23105	COG1063	alcohol dehydrogenase
C2H82_RS23110	COG3265	gluconokinase activity
C2H82_RS23115	COG1064	alcohol dehydrogenase
C2H82_RS23130	COG0582	viral genome integration into host DNA
C2H82_RS23165	COG3385	transposase activity
C2H82_RS23170	COG2814	Major facilitator Superfamily
C2H82_RS23175	COG0673	inositol 2-dehydrogenase activity
C2H82_RS23200	COG2826	transposase and inactivated derivatives, IS30 family
C2H82_RS23215	COG2085	NADP oxidoreductase coenzyme F420-dependent
C2H82_RS23220	COG1120	ATPase activity
C2H82_RS23225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H82_RS23230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H82_RS23235	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C2H82_RS23240	COG4772	TonB-dependent receptor
C2H82_RS23245	COG3712	iron ion homeostasis
C2H82_RS23250	COG1595	DNA-templated transcription, initiation
C2H82_RS23265	COG2390	Transcriptional regulator
C2H82_RS23275	COG2610	gluconate transmembrane transporter activity
C2H82_RS23280	COG0129	dihydroxy-acid dehydratase activity
C2H82_RS23285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2H82_RS23290	COG1414	Transcriptional regulator
C2H82_RS23295	COG1349	DNA-binding transcription factor activity
C2H82_RS23300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2H82_RS23305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H82_RS23310	COG0434	BtpA family
C2H82_RS23315	COG3775	system Galactitol-specific IIC component
C2H82_RS23320	COG3414	Phosphotransferase system galactitol-specific IIB component
C2H82_RS23325	COG1363	Peptidase, m42
C2H82_RS23335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C2H82_RS23340	COG3153	acetyltransferase
C2H82_RS23365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2H82_RS23365	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C2H82_RS23375	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
C2H82_RS23380	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C2H82_RS23395	COG0582	viral genome integration into host DNA
C2H82_RS23400	COG4974	Belongs to the 'phage' integrase family
C2H82_RS23410	COG3539	Fimbrial protein
C2H82_RS23415	COG3539	Fimbrial protein
C2H82_RS23420	COG3121	Chaperone
C2H82_RS23425	COG3188	usher protein
C2H82_RS23430	COG3539	Fimbrial protein
C2H82_RS23435	COG3539	Fimbrial protein
C2H82_RS23440	COG3539	Fimbrial protein
C2H82_RS23445	COG2610	gluconate transmembrane transporter activity
C2H82_RS23460	COG0246	Mannitol dehydrogenase
C2H82_RS23470	COG2186	Transcriptional regulator
C2H82_RS23490	COG0583	DNA-binding transcription factor activity
C2H82_RS23495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C2H82_RS23500	COG0700	Nucleoside recognition
C2H82_RS23505	COG3366	ferrous iron transmembrane transporter activity
C2H82_RS23520	COG0477	Major facilitator Superfamily
C2H82_RS23525	COG3204	pilus organization
C2H82_RS23535	COG1924	4 iron, 4 sulfur cluster binding
C2H82_RS23540	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C2H82_RS23545	COG2733	membrane
C2H82_RS23550	COG2814	Major facilitator Superfamily
C2H82_RS23565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2H82_RS23570	COG5457	Domain of unknown function (DUF1127)
C2H82_RS23580	COG1196	nuclear chromosome segregation
C2H82_RS23590	COG4268	DNA restriction-modification system
C2H82_RS23595	COG1401	restriction endodeoxyribonuclease activity
C2H82_RS23605	COG0732	type I restriction modification DNA specificity domain
C2H82_RS23610	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C2H82_RS23615	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
C2H82_RS23620	COG1715	Restriction endonuclease
C2H82_RS23625	COG0523	cobalamin synthesis protein
C2H82_RS23630	COG2879	small protein
C2H82_RS23635	COG1966	Carbon starvation protein
C2H82_RS23645	COG0840	transmembrane signaling receptor activity
C2H82_RS23650	COG2271	Major facilitator Superfamily
C2H82_RS23655	COG1802	Transcriptional regulator
C2H82_RS23660	COG1063	alcohol dehydrogenase
C2H82_RS23675	COG1484	DNA-dependent DNA replication
C2H82_RS23690	COG2966	Psort location CytoplasmicMembrane, score
C2H82_RS23695	COG2197	response regulator
C2H82_RS23700	COG2197	response regulator
C2H82_RS23705	COG4114	ferric iron reductase
C2H82_RS23735	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C2H82_RS23740	COG0456	acetyltransferase
C2H82_RS23745	COG1011	Hydrolase
C2H82_RS23755	COG2823	Periplasmic or secreted lipoprotein
C2H82_RS23765	COG4667	esterase of the alpha-beta hydrolase superfamily
C2H82_RS23770	COG0084	hydrolase, TatD family'
C2H82_RS23775	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2H82_RS23780	COG1328	CTP reductase activity
C2H82_RS23805	COG3550	peptidyl-serine autophosphorylation
C2H82_RS23815	COG3726	membrane protein affecting hemolysin expression
C2H82_RS23820	COG0560	Phosphoserine phosphatase
C2H82_RS23825	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C2H82_RS23830	COG1056	cytidyltransferase-related domain
C2H82_RS23830	COG3172	ATPase kinase involved in NAD metabolism
C2H82_RS23835	COG0488	(ABC) transporter
C2H82_RS23845	COG0741	lytic transglycosylase activity
C2H82_RS23865	COG3708	Transcriptional regulator
C2H82_RS23865	COG2207	Transcriptional regulator
C2H82_RS23870	COG3045	CreA protein
C2H82_RS23875	COG0745	RESPONSE REGULATOR receiver
C2H82_RS23880	COG2205	protein histidine kinase activity
C2H82_RS23885	COG4452	Inner membrane protein CreD
C2H82_RS23890	COG0745	RESPONSE REGULATOR receiver
C2H82_RS23900	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA