locus-tag class description HT750_RS00010 ENOG4105VZ1 Replication Protein HT750_RS00045 ENOG4105ED4 portal protein HT750_RS00135 ENOG4108US3 tail fiber assembly HT750_RS00140 ENOG4105PTU response to oxidative stress HT750_RS00150 ENOG4108C33 Resolvase HT750_RS00190 ENOG4105ZTC transcriptional activator, Ogr delta HT750_RS00195 ENOG4105C6N Formate acetyltransferase HT750_RS00200 ENOG4105TMB Formate nitrite transporter HT750_RS00205 ENOG4105DDY UPF0142 protein ycaO HT750_RS00210 ENOG4107VMU Membrane HT750_RS00225 ENOG4108K0D peptidase, M48 HT750_RS00235 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HT750_RS00245 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HT750_RS00250 ENOG4105BZ1 (ABC) transporter HT750_RS00260 ENOG4105T0Z Conserved Protein HT750_RS00275 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HT750_RS00280 ENOG4107S90 membrAne HT750_RS00285 ENOG4106371 Methyltransferase HT750_RS00295 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HT750_RS00305 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HT750_RS00310 ENOG4105EAQ (twin-arginine translocation) pathway signal HT750_RS00315 ENOG4105C5X domain protein HT750_RS00320 ENOG4105CGF Aromatic amino acid aminotransferase HT750_RS00325 ENOG4105FCK Membrane HT750_RS00340 ENOG4105CD8 aminopeptidase N HT750_RS00345 ENOG4105E2Y ABC, transporter HT750_RS00350 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HT750_RS00360 ENOG4105GVF (ABC) transporter HT750_RS00365 ENOG4108UZX fmn reductase HT750_RS00370 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon HT750_RS00375 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae HT750_RS00380 ENOG4105CW0 outer membrane usher protein HT750_RS00385 ENOG4108MDY Fimbrial HT750_RS00390 ENOG4105Q7J Fimbrial HT750_RS00395 ENOG4105MX3 Fimbrial HT750_RS00400 ENOG4106PH7 chaperone HT750_RS00410 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HT750_RS00415 ENOG4105QVC MOSC domain-containing protein HT750_RS00425 ENOG4105C5H ABC transporter HT750_RS00430 ENOG4105F1S paraquat-inducible protein a HT750_RS00435 ENOG4105DY2 Paraquat-inducible protein b HT750_RS00440 ENOG4108Q2G (LipO)protein HT750_RS00445 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HT750_RS00455 ENOG4105DAN ATP-dependent protease HT750_RS00465 ENOG4105UYK outer membrane protein a HT750_RS00475 ENOG4108RZ1 DNA transformation protein HT750_RS00480 ENOG4105EM2 membrane HT750_RS00485 ENOG410901E Membrane HT750_RS00490 ENOG41088T4 Helicase IV HT750_RS00505 ENOG4105K4P CoA-binding domain protein HT750_RS00520 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HT750_RS00525 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HT750_RS00530 ENOG4108MN8 Membrane HT750_RS00540 ENOG4105E3S small subunit HT750_RS00545 ENOG4105DPX Hydrogenase, large subunit HT750_RS00550 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HT750_RS00555 ENOG4108USZ hydrogenase HT750_RS00560 ENOG4108VXY Hydrogenase-1 operon protein HyaE HT750_RS00565 ENOG4105MVP hydrogenase-1 operon protein HyaF HT750_RS00570 ENOG4105C4M (Ubiquinol oxidase) subunit I HT750_RS00575 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HT750_RS00585 ENOG4105D6F Phosphatase HT750_RS00590 ENOG41060EU Cold shock-like protein HT750_RS00595 ENOG4105VEQ Cold shock protein HT750_RS00610 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HT750_RS00615 ENOG4105HEE Binding Domain protein HT750_RS00620 ENOG4105BZU Histidine kinase HT750_RS00625 ENOG4108SV3 Tmao reductase system periplasmic protein tort HT750_RS00630 ENOG4106WF9 DNA-binding transcriptional regulator TorR HT750_RS00635 ENOG4105CUW cytochrome C-TYPE protein HT750_RS00640 ENOG4107QY8 reductase HT750_RS00665 ENOG4105D6F Phosphatase HT750_RS00670 ENOG4105XH3 HT750_RS00680 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HT750_RS00685 ENOG4105C2W permease HT750_RS00710 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) HT750_RS00720 ENOG4108R86 Transcriptional regulator HT750_RS00725 ENOG4105C26 Dehydrogenase HT750_RS00735 ENOG4105CK7 Sodium proline symporter HT750_RS00750 ENOG4105DBE peroxidase HT750_RS00755 ENOG4105D5M phosphate starvation-inducible protein HT750_RS00765 ENOG4105CND Glycosyl transferase, family 2 HT750_RS00770 ENOG4107BJW polysaccharide deacetylase HT750_RS00775 ENOG4108TUY outer membrane protein PgaA HT750_RS00780 ENOG4105BZU Histidine kinase HT750_RS00790 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase HT750_RS00800 ENOG4107XHZ cytoplasmic chaperone TorD family protein HT750_RS00805 ENOG4108UQ5 membrane protein YcdZ HT750_RS00810 ENOG4105P8Q Curli production assembly transport component CsgG HT750_RS00815 ENOG4108WYR Curli production assembly transport component, CsgF HT750_RS00820 ENOG4108XDW curli assembly protein CsgE HT750_RS00825 ENOG41086KC Transcriptional regulator HT750_RS00830 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HT750_RS00835 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HT750_RS00850 ENOG4108UVJ appr-1-p processing domain protein HT750_RS00855 ENOG4107RZC phospholipase d HT750_RS00870 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HT750_RS00875 ENOG4105NAC (LipO)protein HT750_RS00880 ENOG4108W47 Acidic protein msyB HT750_RS00890 ENOG4105D1S lipid A biosynthesis HT750_RS00900 ENOG4108YYC ycei family HT750_RS00905 ENOG4105DS1 cytochrome b561 HT750_RS00910 ENOG4106974 biofilm formation HT750_RS00915 ENOG4105F76 Sarcosine oxidase HT750_RS00920 ENOG4105PVA Biofilm formation regulatory protein BssS HT750_RS00925 ENOG4105MEA DNA damage-inducible protein i HT750_RS00935 ENOG4105F3T (LipO)protein HT750_RS00940 ENOG4105E9S glutaredoxin 2 HT750_RS00950 ENOG4105D9U N-acetyltransferase HT750_RS00960 ENOG4105EP9 oxidoreductase HT750_RS00965 ENOG4105CJR Integral membrane protein (MviN HT750_RS00970 ENOG4105QVD Flagella synthesis protein FlgN HT750_RS00975 ENOG4105M9M anti-sigma28 factor FlgM HT750_RS00980 ENOG4105CKS Flagella basal body P-ring formation protein flgA HT750_RS00985 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HT750_RS00990 ENOG4108ZC9 flagellar basal-body rod protein flgc HT750_RS00995 ENOG4105W00 Flagellar hook capping protein HT750_RS01000 ENOG4105BZE flagellar hook protein, FlgE HT750_RS01005 ENOG4108KPB Flagellar basal-body rod protein FlgF HT750_RS01010 ENOG4105CGA flagellar basal-body rod protein FlgG HT750_RS01025 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HT750_RS01030 ENOG4105E1Q flagellar hook-associated protein HT750_RS01035 ENOG4105DTJ flagellar hook-associated protein HT750_RS01050 ENOG4107QQB Ribonuclease E HT750_RS01055 ENOG4105EI2 Pseudouridine synthase HT750_RS01060 ENOG4108UHJ MAF-like protein HT750_RS01065 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HT750_RS01085 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HT750_RS01090 ENOG4105CHR reductase HT750_RS01095 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HT750_RS01100 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HT750_RS01105 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HT750_RS01110 ENOG4105HHA aminodeoxychorismate lyase HT750_RS01120 ENOG4107QRG dna polymerase iii HT750_RS01125 ENOG4105F8V Hydrolase, tatD family HT750_RS01130 ENOG4105CI1 PTS System HT750_RS01135 ENOG4105CNM Receptor HT750_RS01140 ENOG4105K59 histidine triad (HIT) protein HT750_RS01145 ENOG41090DQ Lipoprotein HT750_RS01150 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HT750_RS01170 ENOG4105CEP NADH dehydrogenase HT750_RS01175 ENOG4107MBR 17 kDa surface antigen HT750_RS01180 ENOG4108IND Tetr family transcriptional regulator HT750_RS01185 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HT750_RS01190 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HT750_RS01195 ENOG4108JA2 transcriptioN-repair coupling factor HT750_RS01200 ENOG4105IQC Inner membrane protein YcfT HT750_RS01205 ENOG4105D60 lipoprotein releasing system transmembrane protein HT750_RS01210 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HT750_RS01215 ENOG4105D60 lipoprotein releasing system transmembrane protein HT750_RS01225 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HT750_RS01240 ENOG4107RUE extracellular solute-binding protein family 1 HT750_RS01245 ENOG4105D38 putrescine abc transporter HT750_RS01255 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HT750_RS01265 ENOG4105EZE Cupin 4 family protein HT750_RS01270 ENOG4105IFJ Histidine kinase HT750_RS01275 ENOG4105XJC Two component transcriptional regulator (Winged helix family HT750_RS01280 ENOG4107QTF adenylosuccinate lyase HT750_RS01305 ENOG4108HMX isocitrate dehydrogenase (NADP) HT750_RS01320 ENOG41064WM Uncharacterized protein YcgX HT750_RS01325 ENOG4108XDN Transcriptional regulator HT750_RS01330 ENOG4105BZU Histidine kinase HT750_RS01335 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component HT750_RS01340 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB HT750_RS01350 ENOG410738I uncharacterized protein ymgC HT750_RS01355 ENOG4105BZU Histidine kinase HT750_RS01370 ENOG410658X HT750_RS01410 ENOG4107QMS site-determining protein HT750_RS01420 ENOG4105S66 prophage protein HT750_RS01425 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HT750_RS01435 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HT750_RS01445 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells HT750_RS01450 ENOG4105KT5 UmuD protein HT750_RS01455 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HT750_RS01460 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) HT750_RS01475 ENOG4105ED1 spovr family HT750_RS01485 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HT750_RS01505 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HT750_RS01515 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HT750_RS01530 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HT750_RS01535 ENOG4108BSC Methyltransferase HT750_RS01540 ENOG4105E0A ABC, transporter HT750_RS01545 ENOG4105EHG Permease protein HT750_RS01550 ENOG4105S10 periplasmic binding protein HT750_RS01565 ENOG4105VDH Dihydroxyacetone kinase HT750_RS01570 ENOG4108UTZ Dihydroxyacetone kinase HT750_RS01575 ENOG4105CMT Dihydroxyacetone kinase HT750_RS01580 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HT750_RS01590 ENOG4105C3G gtp-binding protein HT750_RS01600 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HT750_RS01605 ENOG4105CHH sulfate transporter HT750_RS01610 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HT750_RS01635 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HT750_RS01640 ENOG4108YY7 Invasion gene expression up-regulator SirB HT750_RS01645 ENOG41063JG Transcriptional regulator HT750_RS01670 ENOG4105EWV Sodium calcium exchanger membrane region HT750_RS01675 ENOG4105WS7 Cation transport regulator HT750_RS01680 ENOG4108NH8 Cation transport protein HT750_RS01685 ENOG41090EX DsrE family HT750_RS01690 ENOG4105ID0 Putative invasin HT750_RS01695 ENOG4105WH1 Two component transcriptional regulator luxr family HT750_RS01700 ENOG4105BZU Histidine kinase HT750_RS01705 ENOG4105DQQ Major facilitator superfamily MFS_1 HT750_RS01710 ENOG4105CRU nitrate reductase, alpha subunit HT750_RS01715 ENOG4108IUE nitrate reductase beta subunit HT750_RS01720 ENOG4105R3A Nitrate reductase HT750_RS01725 ENOG41076YT nitrate reductase, gamma subunit HT750_RS01750 ENOG4105CIY formyltetrahydrofolate deformylase HT750_RS01760 ENOG4105D78 K07001 NTE family protein HT750_RS01765 ENOG4105I93 response regulator HT750_RS01770 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HT750_RS01775 ENOG4108SAU DNA-binding protein H-ns HT750_RS01780 ENOG4107104 thymidine kinase HT750_RS01785 ENOG4105VNT transposase (IS4 family) protein HT750_RS01790 ENOG4105C0A alcohol dehydrogenase HT750_RS01795 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HT750_RS01805 ENOG4108J59 Extracellular solute-binding protein, family 5 HT750_RS01810 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HT750_RS01815 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HT750_RS01820 ENOG4105C3U ABC transporter HT750_RS01825 ENOG4108JQ7 (ABC) transporter HT750_RS01845 ENOG4107SVH Potassium channel protein HT750_RS01850 ENOG4105K9H YciI-like protein HT750_RS01855 ENOG410822N TonB family HT750_RS01860 ENOG4105NAU thioesterase Superfamily protein HT750_RS01880 ENOG4105EIF outer membrane protein W HT750_RS01885 ENOG4108N8X transition metal ion binding HT750_RS01890 ENOG4108Z9Z response to DNA damage stimulus HT750_RS01910 ENOG4105DK0 Indole-3-glycerol phosphate synthase HT750_RS01915 ENOG4108EFP Anthranilate synthase component II HT750_RS01920 ENOG4105CRQ synthase (Component I) HT750_RS01930 ENOG4105DB7 PHP domain protein HT750_RS01935 ENOG4107RTD sua5 ycio yrdc ywlc family protein HT750_RS01940 ENOG4105EG3 transmembrane signal peptide protein HT750_RS01945 ENOG4105FE9 pseudouridine synthase HT750_RS01960 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HT750_RS01965 ENOG4105UBK short-chain dehydrogenase reductase HT750_RS01970 ENOG4105ERU peptidase HT750_RS01975 ENOG4105RKX Protein of unknown function (DUF2498) HT750_RS01980 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HT750_RS01985 ENOG4107R11 Transcriptional regulator HT750_RS02005 ENOG4107QM5 aconitate hydratase HT750_RS02015 ENOG4105EYK Phosphatidylglycerophosphatase B HT750_RS02020 ENOG4105Q4A inner membrane protein yciS HT750_RS02025 ENOG4105CFV Tetratricopeptide repeat protein HT750_RS02035 ENOG4108ZJT translation initiation factor, Sui1 HT750_RS02045 ENOG4105N2W Transcriptional regulator HT750_RS02050 ENOG410643D UPF0509 protein HT750_RS02055 ENOG4105BZU Histidine kinase HT750_RS02070 ENOG4105Q4T oxidoreductase HT750_RS02075 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HT750_RS02080 ENOG41067SE Tetr family transcriptional regulator HT750_RS02085 ENOG4105C1P efflux transporter, rnd family, mfp subunit HT750_RS02090 ENOG4105BZS acriflavin resistance protein HT750_RS02095 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HT750_RS02100 ENOG4105C2C drug resistance transporter, Bcr CflA HT750_RS02105 ENOG4108JQ2 peptide transport system atp-binding protein HT750_RS02110 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HT750_RS02115 ENOG4108EU3 peptide transport system, permease HT750_RS02120 ENOG4108I5W peptide transport system, permease protein HT750_RS02125 ENOG4108HIY periplasmic HT750_RS02130 ENOG4105N0E Protein of unknown function (DUF2543) HT750_RS02135 ENOG4105CUB amino acid HT750_RS02145 ENOG4105CFQ glutamine synthetase HT750_RS02150 ENOG4108Z86 Glutamine amidotransferase HT750_RS02155 ENOG4107VRI Transcriptional regulator HT750_RS02160 ENOG4105C26 Dehydrogenase HT750_RS02165 ENOG4105CJP fad dependent oxidoreductase HT750_RS02170 ENOG4108JPW Aminotransferase HT750_RS02175 ENOG4105E51 psp operon transcriptional activator HT750_RS02180 ENOG41087YS Phage shock protein A HT750_RS02185 ENOG4105YYT phage shock protein B HT750_RS02190 ENOG4105FM1 phage shock protein C HT750_RS02195 ENOG4105NNG Peripheral inner membrane phage-shock protein HT750_RS02200 ENOG4105K8Z Phage shock protein HT750_RS02205 ENOG4107QW3 Sucrose phosphorylase HT750_RS02210 ENOG4105WEM extracellular solute-binding protein HT750_RS02215 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component HT750_RS02220 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component HT750_RS02225 ENOG4107RRD Dehydrogenase HT750_RS02230 ENOG4107TYA transient receptor potential locus HT750_RS02235 ENOG4105CK5 oxidoreductase HT750_RS02240 ENOG4105C71 hydrolase family 65, central catalytic HT750_RS02245 ENOG4107URF beta-phospho-glucomutase HT750_RS02250 ENOG4108IJ9 (ABC) transporter HT750_RS02255 ENOG4107EFV Outer membrane protein G HT750_RS02260 ENOG4105FKQ transcriptional regulator HT750_RS02265 ENOG4105CM6 amino acid regulated cytosolic protein HT750_RS02275 ENOG4108JU8 Transcriptional regulator HT750_RS02280 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HT750_RS02285 ENOG4107S8C mandelate racemase muconate lactonizing HT750_RS02290 ENOG4105KXI murein peptide amidase A HT750_RS02295 ENOG4107QSI ABC, transporter HT750_RS02300 ENOG4105D64 Mechanosensitive ion channel HT750_RS02305 ENOG4105S5I Membrane HT750_RS02310 ENOG4105Q9Y Universal stress protein HT750_RS02315 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HT750_RS02320 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HT750_RS02325 ENOG4105CFC Transporter HT750_RS02330 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B HT750_RS02335 ENOG4105CH2 amidohydrolase HT750_RS02340 ENOG4106KR7 LysR family Transcriptional regulator HT750_RS02345 ENOG4108DG9 Smr protein MutS2 HT750_RS02350 ENOG4105BZU Histidine kinase HT750_RS02360 ENOG4105C1J atp-dependent rna helicase HT750_RS02370 ENOG4108RW8 Universal stress protein F HT750_RS02375 ENOG4105FCK Membrane HT750_RS02380 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HT750_RS02385 ENOG4105IKK cytoplasmic protein HT750_RS02390 ENOG41090X5 Heat shock protein hslJ HT750_RS02395 ENOG4105C5I Dehydrogenase HT750_RS02400 ENOG4107H52 Dicarboxylate transport HT750_RS02405 ENOG410689M (LipO)protein HT750_RS02410 ENOG4105WXT Conserved Protein HT750_RS02415 ENOG4108WFR AraC Family Transcriptional Regulator HT750_RS02420 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein HT750_RS02425 ENOG4108Z0R Transferase HT750_RS02430 ENOG4107S5I aldo keto reductase HT750_RS02440 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase HT750_RS02445 ENOG4108HPI phosphatidate Cytidylyltransferase HT750_RS02450 ENOG4105E8V Alpha Beta Hydrolase Fold protein HT750_RS02455 ENOG41077RS Phosphatase HT750_RS02465 ENOG4105CQ7 ATP-dependent helicase HT750_RS02470 ENOG4107DB1 DUF218 domain HT750_RS02475 ENOG4105C26 Dehydrogenase HT750_RS02480 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HT750_RS02485 ENOG4105CPW cytochrome b561 HT750_RS02490 ENOG4105UPP uncharacterized protein ydcA HT750_RS02495 ENOG4107NK6 Hok/gef family HT750_RS02505 ENOG4105C8Q Methyl-accepting chemotaxis HT750_RS02510 ENOG4105DDW LysR family Transcriptional regulator HT750_RS02515 ENOG4105E32 cytoplasmic protein HT750_RS02525 ENOG4105Z2P Protein of unknown function (DUF465) HT750_RS02530 ENOG4108Z9I -acetyltransferase HT750_RS02535 ENOG4107WE3 acetyltransferase YdcK HT750_RS02540 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HT750_RS02545 ENOG41088CC tellurite resistance protein tehB HT750_RS02550 ENOG4108KKZ (LipO)protein HT750_RS02560 ENOG4105D7V transposase HT750_RS02565 ENOG4105DKK Benzoate HT750_RS02570 ENOG4108JCI Transcriptional regulator HT750_RS02575 ENOG4105CFP Peptidase U32 HT750_RS02580 ENOG4105RR0 Protein of unknown function (DUF2554) HT750_RS02590 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HT750_RS02595 ENOG4107TYH extracellular solute-binding protein family 1 HT750_RS02600 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HT750_RS02605 ENOG4105D81 ABC transporter, permease HT750_RS02610 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HT750_RS02625 ENOG410654E Membrane HT750_RS02630 ENOG4105R71 cytoplasmic protein HT750_RS02635 ENOG4108T9Y Inner membrane protein ydcZ HT750_RS02640 ENOG4108Z7F N-acetyltransferase HT750_RS02645 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein HT750_RS02650 ENOG4108WYP Transcriptional regulator HT750_RS02655 ENOG4105CHB tonB-dependent Receptor HT750_RS02660 ENOG4108NS2 receptor HT750_RS02665 ENOG4105C85 amino acid HT750_RS02670 ENOG4108N27 Glutathione S-transferase HT750_RS02680 ENOG4105EUZ Beta-lactamase domain protein HT750_RS02690 ENOG4108MEJ flavin reductase domain protein HT750_RS02695 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HT750_RS02705 ENOG4105JAB phenazine biosynthesis protein, phzf family HT750_RS02710 ENOG4105D0D Nitrate reductase 2, gamma subunit HT750_RS02715 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HT750_RS02720 ENOG4108IUE nitrate reductase beta subunit HT750_RS02725 ENOG4105CRU nitrate reductase, alpha subunit HT750_RS02730 ENOG4107QND Nitrite extrusion protein HT750_RS02735 ENOG4108UI3 Leucine Rich repeat HT750_RS02740 ENOG4108UI3 Leucine Rich repeat HT750_RS02750 ENOG4105RPH Inner membrane protein YddG HT750_RS02760 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HT750_RS02765 ENOG4108MG3 formate dehydrogenase HT750_RS02770 ENOG41084S7 Plasmid maintenance system antidote protein HT750_RS02780 ENOG4105DQ4 alcohol dehydrogenase HT750_RS02790 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HT750_RS02795 ENOG4105TPS biofilm-dependent modulation protein HT750_RS02800 ENOG4108Z9K Osmotically inducible protein HT750_RS02805 ENOG4107H6U ABC transporter HT750_RS02810 ENOG4105C3U ABC transporter HT750_RS02815 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HT750_RS02820 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HT750_RS02825 ENOG4105DEF Extracellular solute-binding protein, family 5 HT750_RS02830 ENOG4108UQS dipeptidase HT750_RS02835 ENOG4105BZU Histidine kinase HT750_RS02845 ENOG4105F32 YngK protein HT750_RS02850 ENOG4105E5D amino acid HT750_RS02855 ENOG4105CVK Glutamate decarboxylase HT750_RS02860 ENOG4107RAN Peptidase, M16 HT750_RS02865 ENOG4105PE1 Receptor HT750_RS02870 ENOG4105CQ0 ABC transporter HT750_RS02880 ENOG4105C4X radical SAM domain protein HT750_RS02885 ENOG4105ENH Sulfatase HT750_RS02900 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HT750_RS02905 ENOG4106PIH fimbrial-like protein ydeQ HT750_RS02910 ENOG4106318 fimbrial-like protein YdeR HT750_RS02925 ENOG4108WDE Fimbrial protein HT750_RS02930 ENOG4105CW0 outer membrane usher protein HT750_RS02935 ENOG4108NAE Fimbrial chaperone protein HT750_RS02940 ENOG4108RQP Major type 1 subunit fimbrin HT750_RS02960 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) HT750_RS02995 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound HT750_RS03005 ENOG4105FFC UPF0187 protein HT750_RS03015 ENOG4105BZU Histidine kinase HT750_RS03020 ENOG4105M0C cytoplasmic protein HT750_RS03025 ENOG4105CSV Glutaminase HT750_RS03030 ENOG4105C26 Dehydrogenase HT750_RS03035 ENOG4105EGI Transcriptional regulator HT750_RS03055 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HT750_RS03060 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HT750_RS03065 ENOG4106DNR multiple antibiotic resistance protein HT750_RS03070 ENOG4105CS2 ec 3.2.1.21 HT750_RS03080 ENOG4105VCP PTS System HT750_RS03095 ENOG4105FDP GntR family transcriptional regulator HT750_RS03100 ENOG4108594 Permease of the drug metabolite transporter HT750_RS03105 ENOG4105E5W Transporter HT750_RS03125 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria HT750_RS03130 ENOG4108YDI single-species biofilm formation on inanimate substrate HT750_RS03135 ENOG4105DGW oligopeptidase A HT750_RS03140 ENOG4105EMU Dehydrogenase HT750_RS03145 ENOG4107XBN GntR Family Transcriptional Regulator HT750_RS03150 ENOG41061EV selenium-binding protein YdfZ HT750_RS03155 ENOG4105DEI Mannitol dehydrogenase HT750_RS03165 ENOG4105CPQ Dehydrogenase HT750_RS03170 ENOG4105CXK mandelate racemase muconate lactonizing HT750_RS03185 ENOG4108MK9 spermidine N(1)-acetyltransferase HT750_RS03195 ENOG4105KBG Protein of unknown function (DUF1161) HT750_RS03200 ENOG4107QY8 reductase HT750_RS03205 ENOG4105C3J Cysteine desulfurase HT750_RS03210 ENOG4105QAX Iron-sulfur HT750_RS03215 ENOG4107KGK dmso reductase anchor subunit HT750_RS03220 ENOG4108NEM leader-binding protein dmsD HT750_RS03230 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HT750_RS03235 ENOG4105DAG ROK family HT750_RS03240 ENOG4106NZI LysR family Transcriptional regulator HT750_RS03245 ENOG4105D94 Major Facilitator Superfamily HT750_RS03260 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HT750_RS03275 ENOG4105DSF transport protein HT750_RS03280 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HT750_RS03285 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HT750_RS03290 ENOG4105C5D exported protein HT750_RS03295 ENOG4105D5Q Arginine ornithine antiporter HT750_RS03305 ENOG4105RA2 Membrane HT750_RS03310 ENOG4107EXC regulatoR HT750_RS03315 ENOG4105JJR Histidine kinase HT750_RS03325 ENOG4105C9Q fumarate hydratase class II HT750_RS03330 ENOG4107GFK fumarate HT750_RS03335 ENOG4105EIP mannose-6-phosphate isomerase HT750_RS03340 ENOG4106J39 exported protein HT750_RS03345 ENOG4108QNI outer membrane porin protein HT750_RS03350 ENOG4105CT4 transporter HT750_RS03355 ENOG4105CNT hydrolase family 2 HT750_RS03360 ENOG4105XEA Tetr family transcriptional regulator HT750_RS03365 ENOG4107ZQV short-chain dehydrogenase reductase HT750_RS03370 ENOG4107P2S Transcriptional regulator HT750_RS03375 ENOG4105CI1 PTS System HT750_RS03380 ENOG4105C87 Aminotransferase class I and II HT750_RS03390 ENOG4105D9R oxidoreductase HT750_RS03395 ENOG4106C6R beta-lactam resistance protein HT750_RS03400 ENOG4105QZ5 OriC-binding nucleoid-associated protein HT750_RS03405 ENOG4105M9B inner membrane protein ydgK HT750_RS03430 ENOG4108UQQ Electron transport complex HT750_RS03440 ENOG4105CSM endonuclease III HT750_RS03445 ENOG4105DUX Transporter HT750_RS03450 ENOG4108K3A Glutathione S-transferase HT750_RS03455 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HT750_RS03470 ENOG410642K Lysozyme inhibitor HT750_RS03480 ENOG4108XTF Outer Membrane Lipoprotein HT750_RS03495 ENOG4105Y49 secretion protein, HlyD family HT750_RS03500 ENOG4105DSW Fusaric acid resistance protein HT750_RS03505 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HT750_RS03510 ENOG4107RGM aldo keto reductase HT750_RS03515 ENOG4105XZD Fe-S protein HT750_RS03520 ENOG4108WUH Transcriptional regulator, TetR family HT750_RS03525 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HT750_RS03530 ENOG4108UYE Lactoylglutathione lyase HT750_RS03540 ENOG4107QRT dEAD DEAH box helicase HT750_RS03545 ENOG4105M2J Glutaredoxin HT750_RS03550 ENOG4105K4H Nlp p60 protein HT750_RS03555 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HT750_RS03560 ENOG4105F27 Major Facilitator HT750_RS03575 ENOG4105F52 Transcriptional regulator HT750_RS03580 ENOG4105CZQ inner membrane transport protein YdhC HT750_RS03585 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HT750_RS03590 ENOG4108R6K riboflavin synthase, subunit alpha HT750_RS03615 ENOG4105N0V mono-oxygenase ydhR HT750_RS03620 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HT750_RS03625 ENOG4108Y7C Conserved Protein HT750_RS03630 ENOG4108NWD Cytochrome HT750_RS03635 ENOG4108393 oxidoreductase Fe-S subunit HT750_RS03640 ENOG4105JVW HT750_RS03645 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HT750_RS03650 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein HT750_RS03655 ENOG4105RFR Protein of unknown function (DUF2767) HT750_RS03660 ENOG4105CA9 Pyruvate kinase HT750_RS03665 ENOG4105KMX major outer membrane lipoprotein HT750_RS03670 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HT750_RS03685 ENOG4105JRK feS assembly protein SufD HT750_RS03690 ENOG4105C3K feS assembly ATPase SufC HT750_RS03695 ENOG4105DIW FeS assembly protein SUFB HT750_RS03700 ENOG4108Z4V iron-sulfur cluster assembly HT750_RS03705 ENOG410671Z uncharacterized protein ydiH HT750_RS03710 ENOG4105KA0 thioesterase Superfamily protein HT750_RS03715 ENOG4105CQB FAD linked oxidase domain protein HT750_RS03720 ENOG4105IPI Membrane HT750_RS03730 ENOG4105SUA Ydil protein HT750_RS03735 ENOG4105EMV Major Facilitator HT750_RS03740 ENOG4105EMV Major Facilitator HT750_RS03755 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HT750_RS03760 ENOG4105C1G acyl-Coa dehydrogenase HT750_RS03765 ENOG4105W4W Transcriptional regulator HT750_RS03770 ENOG4105CV7 Electron transfer flavoprotein HT750_RS03775 ENOG4105C10 Electron transfer flavoprotein HT750_RS03780 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HT750_RS03785 ENOG41090P5 ferredoxin-like protein HT750_RS03790 ENOG4105CEY Amp-dependent synthetase and ligase HT750_RS03795 ENOG41061TZ Short-chain dehydrogenase reductase Sdr HT750_RS03805 ENOG4105C5I Dehydrogenase HT750_RS03810 ENOG4107QPK )-transporter HT750_RS03815 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HT750_RS03825 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HT750_RS03840 ENOG4108TC0 Diguanylate phosphodiesterase HT750_RS03845 ENOG4108QBX (LipO)protein HT750_RS03855 ENOG4108V06 Glutathione peroxidase HT750_RS03890 ENOG41082NX 50s ribosomal protein l35 HT750_RS03895 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HT750_RS03915 ENOG4108NE3 Salt-induced outer membrane protein HT750_RS03920 ENOG4105DE4 1-phosphofructokinase HT750_RS03925 ENOG4105P10 Uncharacterized protein ydiZ HT750_RS03935 ENOG4107PN8 YfeABCD locus regulator HT750_RS03940 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HT750_RS03945 ENOG4107K5X Membrane-bound metal-dependent hydrolase HT750_RS03950 ENOG4108ETY sodium dicarboxylate symporter HT750_RS03965 ENOG4105CH6 catalase HT750_RS03970 ENOG410901P UPF0249 protein HT750_RS03975 ENOG4105F8D glycoside hydrolase family 4 HT750_RS03980 ENOG4105EZV Transcriptional regulator HT750_RS03985 ENOG4105VCP PTS System HT750_RS03990 ENOG4105CK1 PTS System HT750_RS03995 ENOG4105VZJ PTS System HT750_RS04000 ENOG4105KKI DNA-binding transcriptional activator OsmE HT750_RS04010 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HT750_RS04020 ENOG4108SPG Periplasmic Protein HT750_RS04030 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) HT750_RS04050 ENOG4105CGK Exodeoxyribonuclease III HT750_RS04055 ENOG4108RSN SNARE associated Golgi HT750_RS04060 ENOG4108KCW iron-sulfur cluster binding HT750_RS04065 ENOG4108N5C SNARE associated Golgi protein-related protein HT750_RS04070 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HT750_RS04075 ENOG4105VNH ABC transporter solute-binding protein HT750_RS04080 ENOG4105CXZ ABC transporter, permease HT750_RS04085 ENOG4108VGW abc transporter atp-binding protein HT750_RS04090 ENOG4107RM6 sulfurtransferase HT750_RS04095 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HT750_RS04100 ENOG4105M6F mutator MutT protein HT750_RS04105 ENOG4105MTM Protein of unknown function (DUF1496) HT750_RS04110 ENOG4105D82 Glutamate dehydrogenase HT750_RS04115 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HT750_RS04120 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) HT750_RS04125 ENOG41069NU Nitroreductase HT750_RS04130 ENOG4105D07 Signal peptide peptidase, SppA HT750_RS04135 ENOG4105HDK L-asparaginase HT750_RS04140 ENOG4108RWI nicotinamidase HT750_RS04145 ENOG4108KUU Inner membrane metabolite transport protein ydjE HT750_RS04150 ENOG4105E98 transcriptional regulator DeoR family HT750_RS04155 ENOG4105CPC Aldo Keto reductase HT750_RS04160 ENOG4107UH8 sugar kinase HT750_RS04165 ENOG4105D2N Aldolase HT750_RS04170 ENOG4105CPQ Dehydrogenase HT750_RS04175 ENOG4107TE1 transport protein HT750_RS04180 ENOG4105CPQ Dehydrogenase HT750_RS04185 ENOG4105VUT cytoplasmic protein HT750_RS04195 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HT750_RS04200 ENOG4105DSB aldose 1-epimerase HT750_RS04205 ENOG4105CV8 reductase HT750_RS04210 ENOG4105GNX MltA-interacting MipA family protein HT750_RS04215 ENOG4105CYN Serine protein kinase HT750_RS04225 ENOG4106KTS Inner membrane protein yeaI HT750_RS04230 ENOG4108KHP Diguanylate cyclase HT750_RS04235 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HT750_RS04250 ENOG4105R1U AraC Family Transcriptional Regulator HT750_RS04255 ENOG4105DJ2 Major Facilitator Superfamily HT750_RS04260 ENOG4105K78 MarR family Transcriptional regulator HT750_RS04265 ENOG4105UCG Domain of unknown function (DUF333) HT750_RS04270 ENOG410620I Diguanylate cyclase HT750_RS04275 ENOG4106G4W HT750_RS04285 ENOG4105Y3U Transglycosylase-associated protein HT750_RS04290 ENOG4105YP6 Domain of unknown function (DUF1869) HT750_RS04295 ENOG4108YS1 cytoplasmic protein HT750_RS04305 ENOG4105EJC lysr family transcriptional regulator HT750_RS04310 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HT750_RS04315 ENOG4105C94 Transporter HT750_RS04320 ENOG4105DVW rieske (2Fe-2S) HT750_RS04325 ENOG4105E3J oxidoreductase HT750_RS04330 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HT750_RS04335 ENOG4105CEY Amp-dependent synthetase and ligase HT750_RS04340 ENOG4105Y4Z Outer Membrane Lipoprotein HT750_RS04345 ENOG41072GX Peptidase M22 Glycoprotease HT750_RS04350 ENOG4105DVT helicase HT750_RS04355 ENOG4105M4H endoribonuclease L-psp HT750_RS04360 ENOG4105V2F Uncharacterized protein yoac HT750_RS04370 ENOG4105CRQ synthase (Component I) HT750_RS04375 ENOG4105P8F nudix hydrolase HT750_RS04380 ENOG4105EJQ L-serine dehydratase HT750_RS04385 ENOG4107XTP (EAL) domain protein HT750_RS04390 ENOG4105EE5 Membrane protein terC HT750_RS04395 ENOG4105DAS pts system HT750_RS04400 ENOG4105ETZ PTS System HT750_RS04405 ENOG4105F3R pts system mannose fructose sorbose family iid HT750_RS04420 ENOG4105DHI Methyltransferase HT750_RS04435 ENOG4105Q3Y exported protein HT750_RS04445 ENOG4105TIK HT750_RS04450 ENOG4105J4Q Transcriptional regulator HT750_RS04455 ENOG4105C0R drug resistance transporter emrb qaca subfamily HT750_RS04465 ENOG4105CN1 protease HT750_RS04475 ENOG4108ZGC gaf domain protein HT750_RS04480 ENOG4105H2K paraquat-inducible protein a HT750_RS04485 ENOG4105DY2 Paraquat-inducible protein b HT750_RS04495 ENOG4105WT8 Protein of unknown function (DUF1480) HT750_RS04500 ENOG4105UVW uncharacterized protein yebW HT750_RS04505 ENOG4108R1E Serine threonine protein phosphatase 1 HT750_RS04510 ENOG4108C33 Resolvase HT750_RS04520 ENOG4108US3 tail fiber assembly HT750_RS04525 ENOG4105PTU response to oxidative stress HT750_RS04650 ENOG4108N0N Phage Terminase Large Subunit HT750_RS04655 ENOG4108TFU terminase (Small subunit) HT750_RS04705 ENOG4105RWQ Protein of unknown function (DUF1364) HT750_RS04715 ENOG4105WI6 cell killing protein encoded within cryptic prophage HT750_RS04745 ENOG4105JBR DNA replication protein HT750_RS04750 ENOG4105ZTP Protein of unknown function (DUF1376) HT750_RS04780 ENOG4107C82 Rac prophage HT750_RS04790 ENOG41076J9 exonuclease VIII HT750_RS04800 ENOG4106YAH restriction alleviation and modification enhancement HT750_RS04805 ENOG41070YT Rac prophage HT750_RS04810 ENOG4105QYW Excisionase-like protein from lambdoid prophage 14 HT750_RS04815 ENOG4108I1J Integrase HT750_RS04820 ENOG4105NKT exported protein HT750_RS04825 ENOG4108PNC copper resistance HT750_RS04830 ENOG4105FXM Copper resistance protein HT750_RS04835 ENOG4105MPK DNA polymerase III subunit theta HT750_RS04840 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HT750_RS04845 ENOG4105UMD exodeoxyribonuclease X HT750_RS04850 ENOG4105CUG Oligopeptidase b HT750_RS04855 ENOG4108Q2J Inner membrane protein YebE HT750_RS04865 ENOG4105X2V dna damage-inducible protein HT750_RS04875 ENOG4108UHU Aldolase HT750_RS04880 ENOG4105C01 Dihydroxy-acid dehydratase HT750_RS04885 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HT750_RS04890 ENOG4106KNT transcriptional regulator HT750_RS04895 ENOG4105CA9 Pyruvate kinase HT750_RS04900 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HT750_RS04905 ENOG4105DR5 peptidase HT750_RS04910 ENOG4105NXV High-affinity zinc uptake system protein HT750_RS04920 ENOG4105FAV ABC, transporter HT750_RS04945 ENOG4107S01 Repressor protein MetJ HT750_RS04955 ENOG4105CDY transcriptional regulatory protein HT750_RS04960 ENOG4108TIT dATP pyrophosphohydrolase HT750_RS04970 ENOG4105D3W isochorismatase HT750_RS04975 ENOG41081XQ Conserved Protein HT750_RS04980 ENOG4105WJG Glutathione HT750_RS04995 ENOG4107QY8 reductase HT750_RS05000 ENOG4105CUW cytochrome C-TYPE protein HT750_RS05010 ENOG4106ZCM YecM protein HT750_RS05020 ENOG4105W13 flagellar protein HT750_RS05025 ENOG4105D7B Flagellar biosynthesis protein flha HT750_RS05030 ENOG4105D00 flagellar biosynthetic protein flhB HT750_RS05035 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HT750_RS05040 ENOG4108VYJ response regulator receiver protein HT750_RS05050 ENOG4105BZU Histidine kinase HT750_RS05055 ENOG4105C8Q Methyl-accepting chemotaxis HT750_RS05060 ENOG4105C8Q Methyl-accepting chemotaxis HT750_RS05065 ENOG4108V3W Chemotaxis protein, CheW HT750_RS05070 ENOG4105CBS Chea signal transduction histidine kinase HT750_RS05075 ENOG4105ER2 Ompa motb domain protein HT750_RS05080 ENOG4107RD7 Flagellar Motor Protein, MotA HT750_RS05085 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HT750_RS05095 ENOG4108VA4 Universal stress protein HT750_RS05105 ENOG4108K4C ec 3.1.3.12 HT750_RS05110 ENOG4105CNN ABC, transporter HT750_RS05115 ENOG4105C2J ABC transporter HT750_RS05120 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HT750_RS05125 ENOG4108UEC Ferritin-like protein HT750_RS05130 ENOG4105N4N Protein of unknown function (DUF2766) HT750_RS05140 ENOG4105P23 (LipO)protein HT750_RS05145 ENOG41090A1 ferritin HT750_RS05150 ENOG4105VVZ metal-binding protein HT750_RS05155 ENOG4105E0U tyrosine-specific transport protein HT750_RS05160 ENOG4106RHG Yeca family HT750_RS05190 ENOG4105WH1 Two component transcriptional regulator luxr family HT750_RS05200 ENOG4105XVG cytoplasmic protein HT750_RS05205 ENOG4105VJY transcriptional regulator HT750_RS05210 ENOG4105CDA abc transporter atp-binding protein HT750_RS05215 ENOG4105E5Q amino acid AbC transporter HT750_RS05220 ENOG4105K6H D-cysteine desulfhydrase HT750_RS05225 ENOG4105EAB amino acid AbC transporter HT750_RS05230 ENOG4108M9K flagella biosynthesis protein FliZ HT750_RS05235 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HT750_RS05240 ENOG4105I03 Flagellin HT750_RS05245 ENOG4105DTS flagellar hook-associated HT750_RS05250 ENOG4105MQ3 flagellar protein FliS HT750_RS05255 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) HT750_RS05260 ENOG4105E5K Alpha-amylase HT750_RS05265 ENOG4108W9D (LipO)protein HT750_RS05270 ENOG41066VF YeeE YedE family protein HT750_RS05280 ENOG4108RAV Conserved protein HT750_RS05285 ENOG4105VQ0 flagellar hook-basal body complex protein fliE HT750_RS05290 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HT750_RS05295 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HT750_RS05300 ENOG41090PJ Flagellar assembly protein HT750_RS05305 ENOG4108JIR Flagellum-specific ATP synthase HT750_RS05310 ENOG4105GSA Flagellar export protein flij HT750_RS05315 ENOG4105WF4 Flagellar hook-length control protein HT750_RS05320 ENOG4107ZI8 flagellar basal body-associated protein flil HT750_RS05325 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HT750_RS05330 ENOG4105DD5 Flagellar motor switch protein HT750_RS05335 ENOG4105K0P flagellar biosynthesis protein HT750_RS05340 ENOG4105CN7 Flagellar biosynthetic protein FliP HT750_RS05350 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HT750_RS05355 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HT750_RS05365 ENOG4105YX3 cellular response to acidity HT750_RS05380 ENOG4105VNZ cytoplasmic protein HT750_RS05385 ENOG4105CKW Inner membrane protein yedI HT750_RS05390 ENOG4105FDR Membrane HT750_RS05395 ENOG41090BB DNA mismatch endonuclease (vsr) HT750_RS05400 ENOG4105DVF Cytosine-specific methyltransferase HT750_RS05405 ENOG4105EST Metal Dependent Phosphohydrolase HT750_RS05410 ENOG4105Y0K Inner membrane protein YedR HT750_RS05415 ENOG4105ZIT Porin Gram-negative type HT750_RS05420 ENOG4105TMR Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity) HT750_RS05425 ENOG4107ZY3 Histidine kinase HT750_RS05430 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HT750_RS05435 ENOG4105VT2 5-hydroxyisourate hydrolase HT750_RS05450 ENOG4108MEK Metal-binding protein YodA HT750_RS05455 ENOG4108VKM cytochrome b561 HT750_RS05465 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) HT750_RS05485 ENOG4105CSH Transporter HT750_RS05490 ENOG4105FYV Amp nucleosidase HT750_RS05495 ENOG4105CDY transcriptional regulatory protein HT750_RS05505 ENOG4105UQX Mate efflux family protein HT750_RS05515 ENOG4107R11 Transcriptional regulator HT750_RS05520 ENOG4106P55 Transcriptional regulator HT750_RS05530 ENOG4108PXI ErfK YbiS YcfS YnhG HT750_RS05545 ENOG4108YZT Adenosylcobinamide kinase HT750_RS05570 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HT750_RS05585 ENOG4105CH7 arginosuccinase HT750_RS05590 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HT750_RS05595 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HT750_RS05600 ENOG4105JXH GntR family transcriptional regulator HT750_RS05605 ENOG4108MRH transcriptional regulatory protein HT750_RS05610 ENOG4105HDK L-asparaginase HT750_RS05615 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HT750_RS05625 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) HT750_RS05630 ENOG4105CEE C4-dicarboxylate transporter HT750_RS05635 ENOG4105D7V transposase HT750_RS05645 ENOG4105D44 asparaginase HT750_RS05660 ENOG4107YNJ LysR family Transcriptional regulator HT750_RS05670 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HT750_RS05690 ENOG4108RVA ribokinase HT750_RS05710 ENOG41080QX K07048 phosphotriesterase-related protein HT750_RS05785 ENOG4108F5E vimentin HT750_RS05790 ENOG4108YIV HT750_RS05810 ENOG4106H6R UPF0380 protein HT750_RS05815 ENOG4105MFG Antirestriction protein HT750_RS05820 ENOG4108YGG dna repair protein HT750_RS05830 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HT750_RS05860 ENOG4105DR8 Membrane HT750_RS05870 ENOG4105DZ1 carboxypeptidase HT750_RS05875 ENOG4105CJB Exodeoxyribonuclease I HT750_RS05885 ENOG4105CUC YeeE YedE family protein HT750_RS05890 ENOG4105CUB amino acid HT750_RS05900 ENOG4105EQ1 Transcriptional regulator HT750_RS05905 ENOG4107SRH Nad-dependent epimerase dehydratase HT750_RS05910 ENOG4105KRQ Addiction module toxin, Txe YoeB family HT750_RS05915 ENOG4105VTW prevent-host-death family HT750_RS05935 ENOG4105CIH Imidazole acetol-phosphate transaminase HT750_RS05940 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HT750_RS05945 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HT750_RS05965 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HT750_RS05970 ENOG4105C6Y Udp-glucose 6-dehydrogenase HT750_RS05975 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HT750_RS05980 ENOG4105CPK Glycosyl transferase (Group 1 HT750_RS05985 ENOG4108SHN Glycosyl transferase, family 2 HT750_RS06000 ENOG4105C5E polysaccharide biosynthesis protein HT750_RS06020 ENOG4108KMV Glycosyl transferase (Group 1 HT750_RS06030 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HT750_RS06035 ENOG4105G1A colanic acid biosynthesis protein HT750_RS06040 ENOG4107T8Q Glycosyl transferase (Group 1 HT750_RS06045 ENOG4105C74 pyruvyl transferase HT750_RS06050 ENOG4105PSV Polysaccharide Biosynthesis Protein HT750_RS06055 ENOG4105D3Q Sugar transferase HT750_RS06060 ENOG4107QKV phosphomannomutase HT750_RS06065 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HT750_RS06070 ENOG4106CD9 glycosyl transferase group 1 HT750_RS06075 ENOG4105FGF GDP-mannose mannosyl hydrolase HT750_RS06080 ENOG4105C30 Nad-dependent epimerase dehydratase HT750_RS06085 ENOG4105C0K Gdp-mannose 4,6-dehydratase HT750_RS06090 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HT750_RS06095 ENOG4105ECJ Glycosyl Transferase HT750_RS06100 ENOG4108NYJ Colanic acid HT750_RS06105 ENOG4107RXY Glycosyl transferase HT750_RS06110 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HT750_RS06115 ENOG41090RK glycosyl transferase HT750_RS06120 ENOG4105D75 Capsular exopolysaccharide family HT750_RS06125 ENOG4105KJF protein tyrosine phosphatase HT750_RS06130 ENOG4105DAY polysaccharide export protein HT750_RS06135 ENOG4105EE5 Membrane protein terC HT750_RS06140 ENOG4108GAE asmA family HT750_RS06145 ENOG4105DHP deoxycytidine triphosphate deaminase HT750_RS06150 ENOG4105DBI uridine monophosphokinase HT750_RS06155 ENOG4105BZU Histidine kinase HT750_RS06160 ENOG4105D03 DNA-3-methyladenine glycosylase II HT750_RS06165 ENOG4105R8A Heat shock protein HT750_RS06170 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding HT750_RS06175 ENOG4105ZD5 Uncharacterized protein conserved in bacteria (DUF2314) HT750_RS06180 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HT750_RS06185 ENOG4108M24 von Willebrand factor, type A HT750_RS06225 ENOG4105EB3 Histidine kinase HT750_RS06230 ENOG4105E3W Two component transcriptional regulator (Winged helix family HT750_RS06235 ENOG4105KWI UPF0339 protein HT750_RS06240 ENOG4105X54 addiction module antidote protein HT750_RS06250 ENOG4105CFP Peptidase U32 HT750_RS06255 ENOG41076Z6 Uncharacterized protein yegR HT750_RS06270 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HT750_RS06275 ENOG4105DT3 PTS system, galactitol-specific IIc component HT750_RS06280 ENOG41090UW PTS System HT750_RS06285 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HT750_RS06295 ENOG4105D2N Aldolase HT750_RS06300 ENOG4105EIE fructose-bisphosphate aldolase HT750_RS06305 ENOG4105EAA nucleoside HT750_RS06310 ENOG4108KD5 ADP-ribosylation crystallin J1 HT750_RS06315 ENOG4108TFM Kinase, PfkB family HT750_RS06320 ENOG4105FDP GntR family transcriptional regulator HT750_RS06325 ENOG4108UQ1 hydrolase, family 25 HT750_RS06330 ENOG4105DWF phosphomethylpyrimidine kinase HT750_RS06390 ENOG41061MD high-affinity nickel-transporter HT750_RS06395 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HT750_RS06400 ENOG410662B Type-1 fimbrial protein HT750_RS06405 ENOG4105CW0 outer membrane usher protein HT750_RS06410 ENOG4108MQF Chaperone HT750_RS06415 ENOG41063W2 Fimbrial protein HT750_RS06420 ENOG41067AK Protein of unknown function (DUF2574) HT750_RS06425 ENOG4105D1F ATP-binding protein HT750_RS06435 ENOG4108KDT Molybdate metabolism regulator HT750_RS06440 ENOG4108KDT Molybdate metabolism regulator HT750_RS06445 ENOG4108KDT Molybdate metabolism regulator HT750_RS06455 ENOG4105KKX ATPase associated with various cellular activities aaa_5 HT750_RS06460 ENOG4105RD5 HT750_RS06465 ENOG4105DEG Vwa containing coxe family protein HT750_RS06470 ENOG410903U zinc ion binding HT750_RS06475 ENOG4108YCW (LipO)protein HT750_RS06480 ENOG4108W15 Protein of unknown function (DUF1456) HT750_RS06485 ENOG4108NEV two component transcriptional regulator, LytTR family HT750_RS06490 ENOG4108HRK Histidine kinase HT750_RS06495 ENOG4108XDN Transcriptional regulator HT750_RS06505 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HT750_RS06510 ENOG4108IJ8 ABC transporter HT750_RS06515 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HT750_RS06520 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HT750_RS06525 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HT750_RS06530 ENOG4105CXG d-lactate dehydrogenase HT750_RS06535 ENOG41061WM D-Alanyl-D-Alanine HT750_RS06540 ENOG41069YE inner membrane protein yohC HT750_RS06545 ENOG4105KHU inner membrane protein YohD HT750_RS06550 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HT750_RS06555 ENOG4105ETP RND efflux system, outer membrane lipoprotein HT750_RS06565 ENOG4105EQR Transposase IS116 IS110 IS902 HT750_RS06575 ENOG4105DWU Membrane HT750_RS06580 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) HT750_RS06585 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HT750_RS06590 ENOG4105C7K acetolactate synthase HT750_RS06595 ENOG4105C5W Aldolase HT750_RS06600 ENOG4105CGD Nad-dependent epimerase dehydratase HT750_RS06605 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HT750_RS06610 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HT750_RS06625 ENOG41064MM (LipO)protein HT750_RS06630 ENOG4105E5Z arginine transporter ATP-binding subunit HT750_RS06635 ENOG4106PMH Extracellular solute-binding protein family 3 HT750_RS06640 ENOG4105GBT ABC transporter HT750_RS06645 ENOG4105DMR ABC, transporter HT750_RS06650 ENOG4106TNF Periplasmic binding protein HT750_RS06660 ENOG4105RBQ inner membrane protein ybjO HT750_RS06665 ENOG4105D38 putrescine abc transporter HT750_RS06670 ENOG4105F38 ABC transporter, permease HT750_RS06675 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HT750_RS06680 ENOG4107RUE extracellular solute-binding protein family 1 HT750_RS06685 ENOG4108RMJ sensory transduction regulator HT750_RS06695 ENOG4108DBC nitroreductase HT750_RS06700 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HT750_RS06705 ENOG41090BQ Glutaredoxin HT750_RS06710 ENOG4105GWF inner membrane protein YbjM HT750_RS06720 ENOG4108RFG Tetr family transcriptional regulator HT750_RS06725 ENOG4106UW1 Major Facilitator superfamily HT750_RS06730 ENOG4108HCJ Hydrolase HT750_RS06740 ENOG4107QF7 multi-drug HT750_RS06745 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HT750_RS06750 ENOG4107FB0 transcriptional regulator DeoR family HT750_RS06755 ENOG4105DZ1 carboxypeptidase HT750_RS06760 ENOG4108TGY Glutathione S-transferase HT750_RS06765 ENOG4105D8V Glucose sorbosone dehydrogenase HT750_RS06770 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HT750_RS06795 ENOG4105BZU Histidine kinase HT750_RS06810 ENOG4105DEF Extracellular solute-binding protein, family 5 HT750_RS06815 ENOG4108JQ6 ABC transporter HT750_RS06820 ENOG4105D44 asparaginase HT750_RS06825 ENOG4105CVM Molybdenum cofactor synthesis domain protein HT750_RS06830 ENOG4105D06 uba thif-type nad fad binding protein HT750_RS06835 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HT750_RS06840 ENOG4105F1A Pyruvate formate-lyase HT750_RS06850 ENOG4108HCJ Hydrolase HT750_RS06855 ENOG41072TH Protein of unknown function (DUF1479) HT750_RS06865 ENOG4105C5H ABC transporter HT750_RS06870 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HT750_RS06875 ENOG4105F4P )-transporter HT750_RS06880 ENOG4105KST dependent repressor HT750_RS06890 ENOG4108I6E Sulfatase HT750_RS06895 ENOG4108T1M outer membrane protein x HT750_RS06905 ENOG4107AQZ Membrane HT750_RS06915 ENOG4107R0W ABC transporter HT750_RS06920 ENOG4105E5Q amino acid AbC transporter HT750_RS06925 ENOG4105CDA abc transporter atp-binding protein HT750_RS06930 ENOG4105D8X mechanosensitive ion channel HT750_RS06940 ENOG4105ZY9 UPF0379 protein ybiM HT750_RS06945 ENOG4108IU3 tonb-dependent siderophore receptor HT750_RS06955 ENOG4105KSC Transcriptional regulator, TraR DksA family HT750_RS06960 ENOG4105VR4 UPF0379 protein ybiJ HT750_RS06965 ENOG4105DG4 malate L-lactate dehydrogenase HT750_RS06970 ENOG4108MTB glycosyl transferase family HT750_RS06975 ENOG4105DVT helicase HT750_RS06990 ENOG4105C1J atp-dependent rna helicase HT750_RS06995 ENOG4107MVR Transcriptional regulator HT750_RS07005 ENOG4105CJ1 ABC, transporter HT750_RS07010 ENOG4107QWP ABC-2 type transporter HT750_RS07015 ENOG4107QWP ABC-2 type transporter HT750_RS07020 ENOG4105I9U inner membrane protein ybhQ HT750_RS07025 ENOG4105X23 Endonuclease Exonuclease phosphatase HT750_RS07030 ENOG4105DZQ phospholipase D Transphosphatidylase HT750_RS07035 ENOG4107UXM Membrane HT750_RS07040 ENOG410733J conserved inner membrane protein HT750_RS07045 ENOG4105HFZ Membrane HT750_RS07050 ENOG4108ZAF Molybdopterin HT750_RS07055 ENOG4105M00 molybdopterin converting factor, subunit 1 HT750_RS07065 ENOG4108RIR Molybdenum cofactor biosynthesis protein HT750_RS07075 ENOG4105CHW UPF0052 protein HT750_RS07085 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HT750_RS07090 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HT750_RS07105 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HT750_RS07110 ENOG4108V1U phospholipid-binding protein HT750_RS07115 ENOG4105NBR Pectinesterase HT750_RS07120 ENOG4107QM5 aconitate hydratase HT750_RS07125 ENOG4107QPK )-transporter HT750_RS07130 ENOG4105C7F AcnD-accessory protein PrpF HT750_RS07135 ENOG4105F04 LysR family Transcriptional regulator HT750_RS07145 ENOG4108K4B hydrolase HT750_RS07155 ENOG4105E0C molybdate abc transporter HT750_RS07160 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HT750_RS07170 ENOG4105F4R Transcriptional regulator mode HT750_RS07175 ENOG4105DKW ABC transporter HT750_RS07180 ENOG4105CMR udp-glucose 4-epimerase HT750_RS07185 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HT750_RS07195 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HT750_RS07205 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HT750_RS07210 ENOG4105JND homeobox protein HT750_RS07215 ENOG4105PGM cation diffusion facilitator family transporter HT750_RS07220 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HT750_RS07265 ENOG4105UFD tol-pal system protein YbgF HT750_RS07270 ENOG4105KCK Peptidoglycan-associated lipoprotein HT750_RS07280 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HT750_RS07290 ENOG4105E02 MotA TolQ exbB proton channel HT750_RS07295 ENOG4107YD3 Thioesterase HT750_RS07300 ENOG4105KJB cyd operon protein YbgE HT750_RS07310 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HT750_RS07315 ENOG4105C4M (Ubiquinol oxidase) subunit I HT750_RS07330 ENOG4107WFU Glutamate mutase subunit sigma HT750_RS07340 ENOG4105DJI Methylaspartate mutase, E subunit HT750_RS07365 ENOG4107GFK fumarate HT750_RS07370 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HT750_RS07375 ENOG4105ETT transcriptional Regulator, LysR family HT750_RS07380 ENOG4105C84 Histidine ammonia-lyase HT750_RS07385 ENOG41088SP formiminoglutamate hydrolase HT750_RS07390 ENOG4105CI2 imidazolone-5-propionate hydrolase HT750_RS07395 ENOG41090B9 response to stress HT750_RS07400 ENOG4105ETS cytosine purines uracil thiamine allantoin HT750_RS07405 ENOG4105CGP Urocanate hydratase HT750_RS07415 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HT750_RS07425 ENOG4105C7S Dehydrogenase HT750_RS07430 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HT750_RS07435 ENOG4105E33 succinate dehydrogenase HT750_RS07440 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HT750_RS07445 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HT750_RS07450 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HT750_RS07460 ENOG4105BZN citrate synthase HT750_RS07465 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HT750_RS07475 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HT750_RS07480 ENOG4105CTX dehydratase HT750_RS07490 ENOG4105CHR reductase HT750_RS07495 ENOG4105CPQ Dehydrogenase HT750_RS07500 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HT750_RS07505 ENOG41073TP transcriptional regulator HT750_RS07510 ENOG4108KK1 membrane protein AbrB duplication HT750_RS07515 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) HT750_RS07525 ENOG4107R7A Allophanate hydrolase subunit 2 HT750_RS07530 ENOG4105P4J Allophanate hydrolase, subunit 1 HT750_RS07535 ENOG4107QNR UPF0135 protein HT750_RS07540 ENOG4105DUX Transporter HT750_RS07545 ENOG4105CVP deoxyribo-dipyrimidine photolyase HT750_RS07550 ENOG4107SEY Conserved Protein HT750_RS07555 ENOG4105XIQ Protein of unknown function (DUF2517) HT750_RS07580 ENOG4105C08 Histidine kinase HT750_RS07585 ENOG4105EEX Two component transcriptional regulator (Winged helix family HT750_RS07595 ENOG4105CXN decarboxylase HT750_RS07600 ENOG4105D5Q Arginine ornithine antiporter HT750_RS07605 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HT750_RS07610 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HT750_RS07615 ENOG4105EV9 Alpha Beta Hydrolase HT750_RS07620 ENOG4105NNH LexA regulated protein HT750_RS07625 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HT750_RS07635 ENOG41090R7 Ferric uptake HT750_RS07640 ENOG4105GX6 (LipO)protein HT750_RS07655 ENOG4105CI1 PTS System HT750_RS07665 ENOG4105CE4 GlcNAc 6-P deacetylase HT750_RS07670 ENOG4105E2R ROK family HT750_RS07675 ENOG4105D4U had-superfamily hydrolase, subfamily iia HT750_RS07680 ENOG4105CAQ asparagine synthetase HT750_RS07725 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HT750_RS07735 ENOG4105C9A Phoh family HT750_RS07745 ENOG4108JU5 Magnesium and cobalt efflux protein HT750_RS07750 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HT750_RS07755 ENOG4107U91 Rhomboid family HT750_RS07760 ENOG4107RP9 extracellular solute-binding protein, family 3 HT750_RS07765 ENOG4105EAD ABC transporter HT750_RS07770 ENOG4105DRP amino acid AbC transporter HT750_RS07775 ENOG4105CDA abc transporter atp-binding protein HT750_RS07785 ENOG4105F7F Chaperone HT750_RS07790 ENOG4105QFC Hsc56 co-chaperone of HscC HT750_RS07795 ENOG41069CF Protein of unknown function (DUF1266) HT750_RS07800 ENOG4107JFD Sel1 repeat HT750_RS07805 ENOG4105QFC Hsc56 co-chaperone of HscC HT750_RS07810 ENOG41069CF Protein of unknown function (DUF1266) HT750_RS07815 ENOG4105EUU Sel1 domain protein repeat-containing protein HT750_RS07820 ENOG4107PAI alpha helical protein HT750_RS07830 ENOG4108U2H Rare lipoprotein B HT750_RS07835 ENOG4105DJF DNA polymerase III, delta' subunit HT750_RS07845 ENOG4108TGR phosphatase HT750_RS07850 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HT750_RS07860 ENOG4105CJN penicillin-binding protein HT750_RS07865 ENOG4105CNI cell division protein FtsW HT750_RS07870 ENOG4105K6T rare lipoprotein A HT750_RS07875 ENOG4105DZ1 carboxypeptidase HT750_RS07890 ENOG41064T2 transcriptional regulator, lysR family HT750_RS07900 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HT750_RS07920 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) HT750_RS07925 ENOG4105CEE C4-dicarboxylate transporter HT750_RS07930 ENOG4106YYS transcriptional regulatory protein HT750_RS07935 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HT750_RS07940 ENOG4105DUA (citrate (pro-3S)-lyase ligase HT750_RS07950 ENOG4105CI0 Citrate lyase HT750_RS07955 ENOG4105CHY citrate lyase, alpha HT750_RS07970 ENOG4107QPK )-transporter HT750_RS07975 ENOG4105KTS ribonuclease HT750_RS07980 ENOG4105NXH GreA GreB family elongation factor HT750_RS07985 ENOG4108U51 Universal stress protein HT750_RS07990 ENOG4108JU3 Alkyl hydroperoxide reductase HT750_RS07995 ENOG4105D3R alkyl hydroperoxide reductase HT750_RS08000 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HT750_RS08005 ENOG4105DQS Transcriptional regulator HT750_RS08010 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HT750_RS08015 ENOG4105GTN ParB Domain Protein Nuclease HT750_RS08020 ENOG4105CHM Aminotransferase HT750_RS08025 ENOG4107SCQ Iron-containing alcohol dehydrogenase HT750_RS08030 ENOG4105VCD cytoplasmic protein HT750_RS08035 ENOG4105D22 carbon starvation protein HT750_RS08040 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HT750_RS08045 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HT750_RS08050 ENOG4105WQI isochorismatase HT750_RS08055 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HT750_RS08060 ENOG4105E4F Isochorismate synthase HT750_RS08065 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HT750_RS08075 ENOG4105DQ5 transport system permease protein HT750_RS08080 ENOG4105TVJ transport system, permease HT750_RS08085 ENOG4105E0A ABC, transporter HT750_RS08090 ENOG4108QY5 Ferric enterobactin transport protein HT750_RS08095 ENOG4105C0W non-ribosomal peptide synthetase HT750_RS08100 ENOG41085A6 mbth domain-containing protein HT750_RS08105 ENOG4105E93 esterase HT750_RS08110 ENOG4107RNH Outer membrane receptor FepA HT750_RS08115 ENOG4108TSE Transferase HT750_RS08130 ENOG4105WQ6 Membrane HT750_RS08135 ENOG4105MSB protein, conserved in bacteria HT750_RS08140 ENOG4108RCM Nitroreductase HT750_RS08145 ENOG4105CUY Mechanosensitive ion channel HT750_RS08150 ENOG4105C85 amino acid HT750_RS08155 ENOG4108IJF Heavy metal efflux pump, CzcA HT750_RS08160 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HT750_RS08165 ENOG410624V efflux system protein HT750_RS08170 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HT750_RS08175 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HT750_RS08180 ENOG4105GR3 Histidine kinase HT750_RS08185 ENOG410802X bacteriophage n4 adsorption protein b HT750_RS08190 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HT750_RS08195 ENOG4105QUW HT750_RS08205 ENOG4108NC2 Outer membrane protease HT750_RS08220 ENOG4108WF3 methyltransferase HT750_RS08245 ENOG4108X9F tail fiber protein HT750_RS08320 ENOG4105IM0 capsid protein HT750_RS08330 ENOG4105F7J membrane-bound serine protease HT750_RS08340 ENOG4107DE1 head-to-tail joining protein HT750_RS08345 ENOG4105UZW Tail fiber assembly protein HT750_RS08350 ENOG4105FKG DNA packaging protein HT750_RS08355 ENOG4106YSC HT750_RS08360 ENOG4105QYK bacteriophage lambda Bor protein homolog HT750_RS08405 ENOG4105RWQ Protein of unknown function (DUF1364) HT750_RS08410 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 HT750_RS08415 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi HT750_RS08455 ENOG410814C multidrug resistance protein HT750_RS08545 ENOG4108KU3 Integrase HT750_RS08555 ENOG4108Q9V regulatoR HT750_RS08560 ENOG4108ZI2 Fimbrial protein HT750_RS08565 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) HT750_RS08570 ENOG4105CW0 outer membrane usher protein HT750_RS08575 ENOG4108AF8 Chaperone HT750_RS08580 ENOG4108WDE Fimbrial protein HT750_RS08590 ENOG4105WQ3 Rna-binding protein HT750_RS08595 ENOG4105S2T inner membrane protein YbcI HT750_RS08605 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HT750_RS08615 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HT750_RS08620 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HT750_RS08625 ENOG4105C5B carbamate kinase HT750_RS08630 ENOG4105G5A Protein of unknown function (DUF2877) HT750_RS08635 ENOG4107REC cytoplasmic protein HT750_RS08640 ENOG4107R1Q Membrane protein FdrA HT750_RS08645 ENOG4105DG4 malate L-lactate dehydrogenase HT750_RS08650 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HT750_RS08655 ENOG4105S0E allantoin catabolism protein HT750_RS08660 ENOG4105BZW Glycerate kinase HT750_RS08665 ENOG4105DTE Xanthine uracil vitamin C permease HT750_RS08675 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HT750_RS08680 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HT750_RS08685 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HT750_RS08690 ENOG41060W2 glyoxylate carboligase HT750_RS08695 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region HT750_RS08705 ENOG4107653 Transcriptional regulator HT750_RS08715 ENOG4105CV6 ABC transporter, permease HT750_RS08720 ENOG4108I0Y (ABC) transporter HT750_RS08725 ENOG4108UJV acyl-CoA thioesterase i HT750_RS08730 ENOG4105E1F short-chain dehydrogenase reductase HT750_RS08735 ENOG4107QR8 Thioredoxin HT750_RS08740 ENOG4105C4B ABC transporter, permease HT750_RS08745 ENOG41083J0 (ABC) transporter HT750_RS08750 ENOG4107QX8 SPFH domain, Band 7 family protein HT750_RS08755 ENOG4105G5H Membrane HT750_RS08785 ENOG4107RY6 amino acid HT750_RS08790 ENOG4105CSV Glutaminase HT750_RS08795 ENOG4105C59 p-type ATPase HT750_RS08800 ENOG41081XE plasmid maintenance system antidote protein, xre family HT750_RS08805 ENOG41080ET plasmid maintenance system killer protein HT750_RS08810 ENOG4105MBR gumn family HT750_RS08815 ENOG4108Z66 YbaK ebsC protein HT750_RS08820 ENOG4105CGH 5'-nucleotidase HT750_RS08825 ENOG4105EU0 Major facilitator Superfamily HT750_RS08830 ENOG4105CKD glutathione-regulated potassium-efflux system protein HT750_RS08835 ENOG4107RE1 Inosine-guanosine kinase HT750_RS08870 ENOG4107QMP dna polymerase iii subunits gamma and tau HT750_RS08880 ENOG4105WD1 Membrane HT750_RS08885 ENOG4108URS primosomal replication protein n'' HT750_RS08890 ENOG4106428 Protein of unknown function (DUF2496) HT750_RS08895 ENOG4105EGS Mechanosensitive ion channel HT750_RS08900 ENOG4107XI7 Tetr family transcriptional regulator HT750_RS08905 ENOG4105C1P efflux transporter, rnd family, mfp subunit HT750_RS08910 ENOG4105BZS acriflavin resistance protein HT750_RS08915 ENOG4108UKR Biofilm formation regulator YbaJ HT750_RS08920 ENOG4105KF5 hemolysin expression-modulating protein HT750_RS08925 ENOG4108UW5 maltose o-acetyltransferase HT750_RS08930 ENOG4105GSJ Inner membrane protein ylaC HT750_RS08935 ENOG41066DG (EAL) domain protein HT750_RS08940 ENOG4105KCV RNA signal recognition particle 4.5S RNA HT750_RS08950 ENOG41080UX Methyltransferase HT750_RS08955 ENOG4108MNP Glycoprotein polysaccharide metabolism HT750_RS08960 ENOG4105C29 acyl-CoA thioesterase HT750_RS08965 ENOG4105BZU Histidine kinase HT750_RS08970 ENOG4108YZA Nitrogen regulatory protein pii HT750_RS08975 ENOG4105BZ1 (ABC) transporter HT750_RS08980 ENOG4105BZ1 (ABC) transporter HT750_RS08985 ENOG4108XM1 transcriptional regulator AsnC family HT750_RS08995 ENOG4108NFA extracellular solute-binding protein HT750_RS09005 ENOG4108TGP Thioesterase superfamily protein HT750_RS09010 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HT750_RS09015 ENOG4105EIN peptidylprolyl cis-trans isomerase HT750_RS09020 ENOG4105K70 DNA-binding protein HT750_RS09025 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HT750_RS09045 ENOG4105M85 Bola protein HT750_RS09050 ENOG4105IEY (LipO)protein HT750_RS09055 ENOG4105EYM Major Facilitator superfamily HT750_RS09060 ENOG4105E2S oxidase) subunit II HT750_RS09065 ENOG4105BZ9 Cytochrome C oxidase, subunit I HT750_RS09070 ENOG4105CCU oxidase (Subunit III) HT750_RS09075 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HT750_RS09100 ENOG4107RDB Major Facilitator HT750_RS09110 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HT750_RS09115 ENOG4107S0N DJ-1 family HT750_RS09130 ENOG4105CTB Polyprenyl synthetase HT750_RS09140 ENOG4105CPC Aldo Keto reductase HT750_RS09145 ENOG4108ZAI phosphatidylglycerophosphatase a HT750_RS09150 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HT750_RS09160 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) HT750_RS09165 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HT750_RS09180 ENOG4105D7V transposase HT750_RS09195 ENOG4105DRB nucleoside-specific channel-forming protein HT750_RS09200 ENOG4105N1F Hnh endonuclease HT750_RS09210 ENOG4105X54 addiction module antidote protein HT750_RS09215 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HT750_RS09220 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HT750_RS09225 ENOG4105VIE preprotein translocase, subunit YajC HT750_RS09240 ENOG4108ZYK Acyl carrier protein phosphodiesterase HT750_RS09250 ENOG4107R28 alpha amylase, catalytic region HT750_RS09255 ENOG4105C85 amino acid HT750_RS09260 ENOG4105CWM branched-chain amino acid transport system II carrier protein HT750_RS09265 ENOG4105BZU Histidine kinase HT750_RS09270 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HT750_RS09275 ENOG4107RH8 nuclease SbcCD subunit D HT750_RS09280 ENOG4105EYH Exonuclease HT750_RS09285 ENOG4105F27 Major Facilitator HT750_RS09290 ENOG4105DKQ ROK family HT750_RS09315 ENOG4105HBA AroM protein HT750_RS09320 ENOG4105SS3 HT750_RS09335 ENOG4105II7 pyrroline-5-carboxylate reductase HT750_RS09340 ENOG4105BZU Histidine kinase HT750_RS09345 ENOG4105VIF phosphate starvation-inducible protein HT750_RS09350 ENOG4105G6Z alkaline phosphatase HT750_RS09365 ENOG4105CPF Cell wall formation (By similarity) HT750_RS09370 ENOG4105UNH Membrane HT750_RS09375 ENOG4105FR5 inner membrane protein YaiY HT750_RS09380 ENOG4107QS8 (LipO)protein HT750_RS09385 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HT750_RS09390 ENOG4107R6D beta-lactam binding protein AmpH HT750_RS09395 ENOG4108PNB DNA-binding transcriptional regulator HT750_RS09405 ENOG4105D52 delta-aminolevulinic acid dehydratase HT750_RS09410 ENOG4105E2B Taurine dioxygenase HT750_RS09415 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HT750_RS09425 ENOG4106FTQ Taurine ABC transporter, periplasmic HT750_RS09430 ENOG4107W19 lmbE family HT750_RS09435 ENOG4108PBI Polysaccharide metabolism HT750_RS09445 ENOG4105SRB Uncharacterized protein yaiO HT750_RS09465 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HT750_RS09470 ENOG4108SC4 )-transporter HT750_RS09505 ENOG4108K2P TRANSCRIPTIONal HT750_RS09510 ENOG4105ETE Transcriptional regulator (LacI family HT750_RS09520 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HT750_RS09525 ENOG4108UW5 maltose o-acetyltransferase HT750_RS09530 ENOG4105DJ2 Major Facilitator Superfamily HT750_RS09540 ENOG4107B2H carbonic anhydrase HT750_RS09545 ENOG4105DND Transcriptional regulator HT750_RS09550 ENOG4105DZC cytosine deaminase HT750_RS09555 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HT750_RS09560 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HT750_RS09565 ENOG4105DXD 2-methylcitrate dehydratase HT750_RS09570 ENOG4105BZN citrate synthase HT750_RS09575 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HT750_RS09580 ENOG4105ENX hydrolase HT750_RS09585 ENOG410642W LysR family Transcriptional regulator HT750_RS09590 ENOG4105EQ2 LysR family Transcriptional regulator HT750_RS09595 ENOG4107SET aldo keto reductase HT750_RS09615 ENOG4105CV8 reductase HT750_RS09620 ENOG4108KBJ Inner membrane protein YkgB HT750_RS09625 ENOG41066GK UPF0379 protein ykgI HT750_RS09630 ENOG4107QN2 dihydrolipoyl dehydrogenase HT750_RS09635 ENOG4108K01 transcriptional regulator HT750_RS09640 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HT750_RS09645 ENOG4107QR9 Iron-sulfur cluster binding protein HT750_RS09650 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HT750_RS09670 ENOG4105C94 Transporter HT750_RS09675 ENOG4105BZU Histidine kinase HT750_RS09680 ENOG4108NUU Transcriptional regulator HT750_RS09685 ENOG4105SZ2 membrAne HT750_RS09690 ENOG4107SNB ankyrin repeat protein YahD HT750_RS09695 ENOG4105N16 Protein of unknown function (DUF2877) HT750_RS09700 ENOG4107R1Q Membrane protein FdrA HT750_RS09705 ENOG4107REC cytoplasmic protein HT750_RS09710 ENOG4105C5B carbamate kinase HT750_RS09715 ENOG4105DZC cytosine deaminase HT750_RS09720 ENOG4105DQ4 alcohol dehydrogenase HT750_RS09735 ENOG4105E82 cytochrome subunit of dehydrogenase HT750_RS09740 ENOG4105TDT uncharacterized protein yahO HT750_RS09745 ENOG4108JU7 Transcriptional regulator HT750_RS09750 ENOG4105CR4 methylisocitrate lyase HT750_RS09795 ENOG4106PYX Receptor HT750_RS09805 ENOG4105PI0 Ferredoxin HT750_RS09810 ENOG4105R3P Inner membrane protein yagU HT750_RS09915 ENOG4105FCK Membrane HT750_RS09925 ENOG4105V1F Fermentation respiration switch protein HT750_RS09935 ENOG4105CIN aminoacyl-histidine dipeptidase HT750_RS09950 ENOG4108S2Y peptide Chain Release factor HT750_RS09960 ENOG4108HYG acetyltransferase HT750_RS09980 ENOG4108UK5 Transposase HT750_RS09985 ENOG4108YS0 lipoprotein YafL HT750_RS10000 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HT750_RS10005 ENOG4105E7A Glutamine amidotransferase HT750_RS10015 ENOG4107QPN acyl-Coa dehydrogenase HT750_RS10020 ENOG4108WN0 inhibitor of vertebrate lysozyme HT750_RS10025 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HT750_RS10035 ENOG4107RZZ dna polymerase iii epsilon subunit HT750_RS10045 ENOG4105D1A Methyltransferase HT750_RS10050 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) HT750_RS10055 ENOG4105E9H Lytic Murein transglycosylase HT750_RS10060 ENOG4105F2W methyltransferase HT750_RS10070 ENOG4105HEI LysR family (Transcriptional regulator HT750_RS10075 ENOG4105CV8 reductase HT750_RS10110 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HT750_RS10115 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HT750_RS10120 ENOG4108UMI ABC transporter, permease HT750_RS10125 ENOG4105D01 (LipO)protein HT750_RS10130 ENOG4108R8X outer membrane lipoprotein HT750_RS10135 ENOG4108R96 Methyltransferase, YaeB family HT750_RS10145 ENOG4108UY0 (LipO)protein HT750_RS10150 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HT750_RS10155 ENOG4108YZN class I peptide chain release factor HT750_RS10160 ENOG4108VWS Yaeq family HT750_RS10170 ENOG4105M1T rho-binding antiterminator HT750_RS10175 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HT750_RS10180 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HT750_RS10185 ENOG4105CXN decarboxylase HT750_RS10195 ENOG4105C0B DNA polymerase III (alpha subunit) HT750_RS10200 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) HT750_RS10220 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HT750_RS10225 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HT750_RS10235 ENOG4105DZP Membrane-associated zinc metalloprotease HT750_RS10240 ENOG4105KNE Phosphatidate cytidylyltransferase HT750_RS10245 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HT750_RS10250 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HT750_RS10275 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HT750_RS10295 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HT750_RS10300 ENOG4105C0H protease HT750_RS10315 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HT750_RS10320 ENOG4105EN6 Membrane HT750_RS10345 ENOG4105S6R Iron-hydroxamate transporter permease subunit HT750_RS10350 ENOG4105J76 Periplasmic binding protein HT750_RS10355 ENOG4105E0A ABC, transporter HT750_RS10360 ENOG4105E0K tonB-dependent siderophore receptor HT750_RS10365 ENOG4105BZ4 penicillin-binding protein HT750_RS10370 ENOG4105CQ7 ATP-dependent helicase HT750_RS10375 ENOG4107XID 2'-5' rna ligase HT750_RS10390 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) HT750_RS10395 ENOG4105DJ0 Poly(A) Polymerase HT750_RS10400 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HT750_RS10410 ENOG4108VEV chaperone HT750_RS10415 ENOG4105CW0 outer membrane usher protein HT750_RS10420 ENOG4108XEY fimbrial-like adhesin protein HT750_RS10425 ENOG4105SYG Fimbrial protein HT750_RS10430 ENOG4105SN2 fimbrial-like adhesin protein HT750_RS10435 ENOG4105P0Q fimbrial-like protein YadC HT750_RS10450 ENOG4108A32 Transposase HT750_RS10460 ENOG4107BJW polysaccharide deacetylase HT750_RS10465 ENOG4108YTN IIa component HT750_RS10470 ENOG4105E3A (ABC) transporter HT750_RS10475 ENOG4105DA5 (ABC) transporter HT750_RS10480 ENOG41077A9 carbonic anhydrase HT750_RS10485 ENOG4108UGV hypoxanthine phosphoribosyltransferase HT750_RS10490 ENOG4105DZG Dehydrogenase HT750_RS10495 ENOG4105E3B Multicopper oxidase HT750_RS10500 ENOG4108ZRK uncharacterized protein yacC HT750_RS10520 ENOG4107QIJ Aconitate hydratase 2 HT750_RS10525 ENOG4108NST exported protein HT750_RS10535 ENOG4107QN2 dihydrolipoyl dehydrogenase HT750_RS10540 ENOG4107QSN dihydrolipoamide acetyltransferase HT750_RS10545 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HT750_RS10550 ENOG41073TP transcriptional regulator HT750_RS10555 ENOG4105C85 amino acid HT750_RS10560 ENOG4106A72 regulatory protein AmpE HT750_RS10565 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HT750_RS10570 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HT750_RS10575 ENOG4108ZUW Major pilin subunit HT750_RS10580 ENOG4107QHF type ii secretion system protein e HT750_RS10585 ENOG4105D7Q type ii secretion system HT750_RS10595 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HT750_RS10610 ENOG4105M6F mutator MutT protein HT750_RS10630 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HT750_RS10635 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HT750_RS10640 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HT750_RS10645 ENOG4105CPF Cell wall formation (By similarity) HT750_RS10660 ENOG4105CNI cell division protein FtsW HT750_RS10665 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) HT750_RS10675 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HT750_RS10680 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HT750_RS10685 ENOG4105CJN penicillin-binding protein HT750_RS10690 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HT750_RS10705 ENOG4107B7Y DNA-binding transcriptional regulator FruR HT750_RS10715 ENOG4108ZP8 Acetolactate synthase small subunit HT750_RS10720 ENOG4105C7K acetolactate synthase HT750_RS10730 ENOG41064T2 transcriptional regulator, lysR family HT750_RS10775 ENOG4105DP9 ABC transporter HT750_RS10780 ENOG4106SMU thiamine transporter membrane protein HT750_RS10790 ENOG4108KF1 Membrane HT750_RS10805 ENOG41063TF transcriptional regulator (AraC HT750_RS10820 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HT750_RS10825 ENOG4105CQ2 DNA polymerase HT750_RS10830 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HT750_RS10835 ENOG4105D3G Pseudouridine synthase HT750_RS10845 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HT750_RS10855 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HT750_RS10895 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HT750_RS10900 ENOG4105CKD glutathione-regulated potassium-efflux system protein HT750_RS10910 ENOG4105C54 Major Facilitator superfamily HT750_RS10915 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HT750_RS10920 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HT750_RS10935 ENOG4105C94 Transporter HT750_RS10965 ENOG4108XNW Transcriptional activatory protein CaiF HT750_RS10970 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HT750_RS10975 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HT750_RS10995 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HT750_RS11010 ENOG4105DTN riboflavin biosynthesis protein ribF HT750_RS11015 ENOG410647N response to DNA damage stimulus HT750_RS11035 ENOG41063Z6 transcriptional regulator, lysR family HT750_RS11040 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) HT750_RS11050 ENOG41061MV Arylsulfatase HT750_RS11060 ENOG4105WI6 cell killing protein encoded within cryptic prophage HT750_RS11080 ENOG4108QUJ UPF0174 protein YaaW HT750_RS11085 ENOG4106HK8 GPR1 FUN34 yaaH family protein HT750_RS11090 ENOG4108RIR Molybdenum cofactor biosynthesis protein HT750_RS11100 ENOG4105BZG amino acid carrier protein HT750_RS11110 ENOG41062C6 Protein of unknown function (DUF2502) HT750_RS11115 ENOG4105D98 threonine synthase HT750_RS11125 ENOG4105CFH Aspartokinase HT750_RS11135 ENOG4106FVC RNA methyltransferase HT750_RS11140 ENOG410759A HT750_RS11145 ENOG41065U4 response regulator HT750_RS11150 ENOG4105CT7 inner membrane cred family protein HT750_RS11155 ENOG4105EB3 Histidine kinase HT750_RS11160 ENOG4105E3W Two component transcriptional regulator (Winged helix family HT750_RS11165 ENOG4108RH0 Crea protein HT750_RS11170 ENOG4105UEI Transcriptional Regulator AraC Family HT750_RS11190 ENOG4107SC1 transglycosylase HT750_RS11195 ENOG4105C5H ABC transporter HT750_RS11205 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HT750_RS11210 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HT750_RS11215 ENOG4105EAC phosphoserine phosphatase HT750_RS11220 ENOG41062Z9 Membrane HT750_RS11235 ENOG4105D3A purine nucleoside phosphorylase DeoD-type HT750_RS11255 ENOG4105G0K glycine radical enzyme YjjI family HT750_RS11260 ENOG41076CZ activating enzyme HT750_RS11265 ENOG4105EYA deoxyribonuclease HT750_RS11270 ENOG4108NRW Phospholipase, patatin family HT750_RS11280 ENOG4105K3G Periplasmic Protein HT750_RS11290 ENOG4105PAD Hydrolase HT750_RS11295 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HT750_RS11300 ENOG4108WPU DNA polymerase III subunit psi HT750_RS11325 ENOG4105YBH Protein of unknown function (DUF1435) HT750_RS11330 ENOG4108819 ferric iron reductase HT750_RS11335 ENOG4108T94 DNA-binding transcriptional activator BglJ HT750_RS11340 ENOG4108N8T regulatoR HT750_RS11345 ENOG4105DWK Membrane HT750_RS11360 ENOG4106CVF DNA replication protein HT750_RS11365 ENOG4105RI1 glycoprotein receptor HT750_RS11375 ENOG4105CPQ Dehydrogenase HT750_RS11380 ENOG410617M Transcriptional regulator HT750_RS11385 ENOG4108I5G Major Facilitator superfamily HT750_RS11390 ENOG4105C8Q Methyl-accepting chemotaxis HT750_RS11400 ENOG4108IA2 Sodium pantothenate symporter HT750_RS11420 ENOG4105D22 carbon starvation protein HT750_RS11425 ENOG4105VCD cytoplasmic protein HT750_RS11430 ENOG4105CKI cobalamin synthesis protein HT750_RS11445 ENOG4106H3A restriction HT750_RS11465 ENOG4106DIZ Domain of unknown function (DUF1127) HT750_RS11470 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HT750_RS11485 ENOG41083G8 Multidrug resistance protein MdtM HT750_RS11490 ENOG4106BRA Membrane HT750_RS11495 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HT750_RS11500 ENOG4105CIZ coA-substrate-specific enzyme activase HT750_RS11515 ENOG4105CBP Major Facilitator HT750_RS11525 ENOG41074DU domain protein HT750_RS11530 ENOG4108P2H Inner membrane protein YjiG HT750_RS11535 ENOG4105DYB Isoaspartyl dipeptidase HT750_RS11540 ENOG4107YNJ LysR family Transcriptional regulator HT750_RS11560 ENOG4105C6F GntR Family Transcriptional Regulator HT750_RS11565 ENOG4105DEI Mannitol dehydrogenase HT750_RS11575 ENOG4107EFN gluconate transport system permease 3 HT750_RS11580 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HT750_RS11585 ENOG4108T65 Fimbrial HT750_RS11590 ENOG4108SQA Fimbrial HT750_RS11595 ENOG4105CW0 outer membrane usher protein HT750_RS11600 ENOG4108NAE Fimbrial chaperone protein HT750_RS11605 ENOG4108S54 Fimbrial protein HT750_RS11610 ENOG4108RQP Major type 1 subunit fimbrin HT750_RS11615 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off HT750_RS11620 ENOG4108W9T type 1 fimbriae regulatory protein HT750_RS11625 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria HT750_RS11630 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) HT750_RS11650 ENOG4105DZR Type I site-specific deoxyribonuclease HT750_RS11665 ENOG4105CVR type I restriction-modification system HT750_RS11685 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) HT750_RS11700 ENOG4105DQ4 alcohol dehydrogenase HT750_RS11705 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HT750_RS11710 ENOG4105CPQ Dehydrogenase HT750_RS11715 ENOG4105CHR reductase HT750_RS11720 ENOG4105C6Z Gluconate HT750_RS11725 ENOG4105K2J Transcriptional regulator HT750_RS11730 ENOG4105D7A ATP-binding protein HT750_RS11735 ENOG4108K5H permease YjgP YjgQ family protein HT750_RS11740 ENOG4108M8S permease YjgP YjgQ family protein HT750_RS11750 ENOG4105MYG DNA polymerase iii, chi subunit HT750_RS11755 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HT750_RS11760 ENOG4108M3P Membrane HT750_RS11765 ENOG4108MJ3 acetyltransferase HT750_RS11770 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HT750_RS11785 ENOG4105XEP YhcH YjgK YiaL family protein HT750_RS11790 ENOG4108XFH Transcriptional regulator HT750_RS11795 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HT750_RS11800 ENOG4108UQ8 endoribonuclease L-psp HT750_RS11805 ENOG4107C93 pyrBI operon leader peptide HT750_RS11820 ENOG4105KME endoribonuclease L-psp HT750_RS11825 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HT750_RS11835 ENOG4105D4X repressor HT750_RS11840 ENOG4105C5Y PTS System HT750_RS11845 ENOG4105CG3 alpha amylase, catalytic region HT750_RS11850 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HT750_RS11855 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HT750_RS11860 ENOG4105K4U addiction module toxin, RelE StbE family HT750_RS11870 ENOG4108XVM Cytochrome b(562) HT750_RS11875 ENOG4105CMS peptidase U62, modulator of DNA gyrase HT750_RS11885 ENOG4105DFU Cell wall formation (By similarity) HT750_RS11895 ENOG41062B0 ABC transporter, permease HT750_RS11900 ENOG4107R9N ABC transporter HT750_RS11905 ENOG4105C2J ABC transporter HT750_RS11910 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HT750_RS11915 ENOG4105F0N pyrophosphate phospho-hydrolase HT750_RS11920 ENOG4105MZG transcriptional modulator of maze toxin, mazf HT750_RS11925 ENOG41087RY SpoVT_AbrB HT750_RS11930 ENOG4108ZHD aig2 family HT750_RS11935 ENOG4105MA0 exported protein HT750_RS11940 ENOG4105CFU surface antigen HT750_RS11950 ENOG4105C37 (CBS) domain HT750_RS11955 ENOG41061GZ Protein of unknown function (DUF1107) HT750_RS11960 ENOG4108UUE Transcriptional regulator HT750_RS11965 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HT750_RS11970 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HT750_RS11975 ENOG4105KVH Transcriptional regulator HT750_RS11980 ENOG4105ECR NmrA family HT750_RS11985 ENOG4105DXC membrane HT750_RS11995 ENOG4105C85 amino acid HT750_RS12000 ENOG4108V1T peptidylprolyl cis-trans isomerase HT750_RS12005 ENOG4105FHY Opacity-associated protein A HT750_RS12015 ENOG4105CHR reductase HT750_RS12025 ENOG4105E39 Enoyl-CoA hydratase HT750_RS12030 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HT750_RS12035 ENOG4107S3R L-aspartate oxidase HT750_RS12040 ENOG41069H7 transport system small permease component HT750_RS12045 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HT750_RS12050 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HT750_RS12060 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HT750_RS12075 ENOG4105KIT UPF0379 protein yjfY HT750_RS12105 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HT750_RS12120 ENOG4108MXZ Esterase HT750_RS12125 ENOG4105WSB biofilm stress and motility protein A HT750_RS12130 ENOG4105S17 UPF0379 protein yjfN HT750_RS12135 ENOG4105CSU acyl-Coa dehydrogenase HT750_RS12140 ENOG4106032 Glutathionylspermidine synthase HT750_RS12145 ENOG4108KXT Conserved Protein HT750_RS12150 ENOG4105Z6B inner membrane protein yjfl HT750_RS12155 ENOG4107VNS Protein of unknown function (DUF2491) HT750_RS12160 ENOG4108P9J Phage shock protein A HT750_RS12165 ENOG4105FUX Conserved Protein HT750_RS12170 ENOG4105C2N RNA methyltransferase TrmH family group 3 HT750_RS12175 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HT750_RS12195 ENOG4105EPW hflc protein HT750_RS12200 ENOG4107QJR hflk protein HT750_RS12205 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HT750_RS12225 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HT750_RS12230 ENOG4105K8N protein family UPF0079, ATPase HT750_RS12235 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HT750_RS12280 ENOG4105EGS Mechanosensitive ion channel HT750_RS12285 ENOG4106CG8 Inner membrane protein YjeO HT750_RS12305 ENOG4107SC7 Inner membrane transporter yjeM HT750_RS12315 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HT750_RS12320 ENOG4105E33 succinate dehydrogenase HT750_RS12340 ENOG4105QNF Outer membrane lipoprotein HT750_RS12345 ENOG4105KPY Small multidrug resistance protein HT750_RS12350 ENOG4106BSU Entericidin B HT750_RS12355 ENOG4107PEH Entericidin EcnA/B family HT750_RS12365 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HT750_RS12370 ENOG4105MTB Uncharacterized protein YjeJ HT750_RS12375 ENOG4108ZVF (LipO)protein HT750_RS12390 ENOG4105DVH amino acid HT750_RS12395 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HT750_RS12400 ENOG4108IJ0 Aspartate ammonia-lyase HT750_RS12405 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HT750_RS12420 ENOG4108SIC Transcriptional regulator HT750_RS12430 ENOG4108M3R transcriptional activator CadC HT750_RS12435 ENOG4105D5Q Arginine ornithine antiporter HT750_RS12440 ENOG4105CXN decarboxylase HT750_RS12445 ENOG4105DUX Transporter HT750_RS12450 ENOG4105CRK lysyL-tRNA synthetase HT750_RS12465 ENOG410830R acetyltransferase HT750_RS12470 ENOG4105VR1 Pfam:DUF1271 HT750_RS12475 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HT750_RS12480 ENOG4108MRH transcriptional regulatory protein HT750_RS12485 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HT750_RS12490 ENOG4107GFK fumarate HT750_RS12495 ENOG4108R5S membrane HT750_RS12500 ENOG4105F8D glycoside hydrolase family 4 HT750_RS12505 ENOG4108K2B transcriptional regulator HT750_RS12510 ENOG4105CXN decarboxylase HT750_RS12515 ENOG4106ZGR Transcriptional regulator HT750_RS12520 ENOG4105D5Q Arginine ornithine antiporter HT750_RS12525 ENOG4105DIJ Phosphoethanolamine transferase HT750_RS12530 ENOG4105XJC Two component transcriptional regulator (Winged helix family HT750_RS12535 ENOG4105ECM Sensor protein basS pmrB HT750_RS12545 ENOG4105CSH Transporter HT750_RS12550 ENOG4108YIV HT750_RS12555 ENOG4108F5E vimentin HT750_RS12560 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HT750_RS12565 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HT750_RS12570 ENOG4105D5T phosphonate abc transporter HT750_RS12575 ENOG4105EHI Phosphonate ABC transporter, periplasmic HT750_RS12585 ENOG4107RJJ Transcriptional regulator HT750_RS12590 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HT750_RS12595 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HT750_RS12600 ENOG4105EKV Phosphonate metabolism protein HT750_RS12605 ENOG4105FT8 Phosphonate metabolism HT750_RS12610 ENOG4105ENV phosphonate C-P lyase system protein PhnK HT750_RS12615 ENOG4105HRV phosphonate c-p lyase system protein phnl HT750_RS12620 ENOG4105FD8 phosphonate metabolism protein PhnM HT750_RS12630 ENOG410849A acetyltransferase, (GNAT) family HT750_RS12635 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HT750_RS12645 ENOG4108YZG isomerase HT750_RS12650 ENOG4105NYY transcriptional regulator, RpiR HT750_RS12655 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HT750_RS12660 ENOG4105C2J ABC transporter HT750_RS12665 ENOG4105CNN ABC, transporter HT750_RS12670 ENOG4105UP7 3-epimerase HT750_RS12675 ENOG4107TFG D-allose kinase HT750_RS12680 ENOG4105EUZ Beta-lactamase domain protein HT750_RS12685 ENOG4106833 HT750_RS12690 ENOG4105J12 Multidrug resistance protein mdtN HT750_RS12695 ENOG4108MI0 Resistance protein HT750_RS12700 ENOG4105ETP RND efflux system, outer membrane lipoprotein HT750_RS12710 ENOG41082ND Uncharacterized protein yjcO HT750_RS12715 ENOG4105CK2 sodium dicarboxylate symporter HT750_RS12720 ENOG4108W0S formate-dependent nitrite reductase complex HT750_RS12730 ENOG4108QKW cytochrome c-type biogenesis protein HT750_RS12735 ENOG4105DVI reductase, NrfD HT750_RS12740 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HT750_RS12745 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HT750_RS12755 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HT750_RS12760 ENOG41062QD Membrane HT750_RS12770 ENOG4105EEQ Na H antiporter HT750_RS12775 ENOG4105C7N Xanthine uracil vitamin C permease HT750_RS12780 ENOG4108Z4X TRANSCRIPTIONal HT750_RS12785 ENOG4108W3Q Transcriptional regulator HT750_RS12790 ENOG4108M8H domain protein HT750_RS12795 ENOG4105PMV Membrane HT750_RS12800 ENOG4108UUM single-stranded DNA-binding protein HT750_RS12805 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HT750_RS12810 ENOG4105MSB protein, conserved in bacteria HT750_RS12815 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HT750_RS12820 ENOG4105F0S class B acid phosphatase HT750_RS12830 ENOG4105CGF Aromatic amino acid aminotransferase HT750_RS12835 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HT750_RS12840 ENOG4105CDU Replicative dna helicase HT750_RS12845 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HT750_RS12850 ENOG4105P4Z Phage shock protein G HT750_RS12855 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HT750_RS12865 ENOG4105MYN Zinc uptake regulation protein HT750_RS12870 ENOG4105VDW Csbd family HT750_RS12875 ENOG4107R73 Mate efflux family protein HT750_RS12885 ENOG41080IJ Diacylglycerol kinase HT750_RS12910 ENOG4107W52 maltose operon periplasmic protein HT750_RS12920 ENOG4108IJ9 (ABC) transporter HT750_RS12925 ENOG4107FKK extracellular solute-binding protein family 1 HT750_RS12930 ENOG4105D56 permease protein HT750_RS12935 ENOG4105EG2 ABC transporter, permease HT750_RS12950 ENOG4105E3R (LipO)protein HT750_RS12955 ENOG4108Q9C Periplasmic Protein HT750_RS12960 ENOG4108MDC (LipO)protein HT750_RS12975 ENOG4105CFH Aspartokinase HT750_RS12990 ENOG4107SC1 transglycosylase HT750_RS13070 ENOG410685N tail fiber protein HT750_RS13085 ENOG410756H nucleotidyltransferase HT750_RS13095 ENOG4108ZR5 Conserved Protein HT750_RS13100 ENOG4105FE9 pseudouridine synthase HT750_RS13105 ENOG4105DKT Transcriptional regulator HT750_RS13110 ENOG4105CHR reductase HT750_RS13115 ENOG4108XCU pts system HT750_RS13120 ENOG4105KPI PTS system sorbose subfamily IIB component HT750_RS13125 ENOG4105ETZ PTS System HT750_RS13130 ENOG4105F3R pts system mannose fructose sorbose family iid HT750_RS13135 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HT750_RS13140 ENOG4105F9E Shikimate 5-dehydrogenase HT750_RS13150 ENOG4105EAM Na Pi-cotransporter HT750_RS13165 ENOG4105C3R Methionine synthase HT750_RS13170 ENOG41069M3 Transcriptional regulator HT750_RS13180 ENOG4108I9X Isocitrate lyase HT750_RS13185 ENOG4107QP3 malate synthase g HT750_RS13195 ENOG4105K5X acetyltransferase HT750_RS13225 ENOG4105C12 Phosphoribosylglycinamide synthetase HT750_RS13230 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HT750_RS13235 ENOG4105BZU Histidine kinase HT750_RS13240 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HT750_RS13245 ENOG4108T8B Protein of unknown function (DUF1481) HT750_RS13255 ENOG4105R2J Conserved Protein HT750_RS13290 ENOG4105D06 uba thif-type nad fad binding protein HT750_RS13295 ENOG4105WHD thiamine biosynthesis protein ThiS HT750_RS13305 ENOG4105D41 biosynthesis protein thiH HT750_RS13325 ENOG4108RVA ribokinase HT750_RS13360 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HT750_RS13365 ENOG4105PM1 preprotein translocase subunit SecE HT750_RS13400 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HT750_RS13430 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) HT750_RS13435 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) HT750_RS13445 ENOG4108Y73 Membrane HT750_RS13450 ENOG4105EJ2 Transcriptional regulator HT750_RS13460 ENOG4105C5Q Transcriptional regulator HT750_RS13465 ENOG4108I5G Major Facilitator superfamily HT750_RS13470 ENOG4105CXK mandelate racemase muconate lactonizing HT750_RS13475 ENOG4105CH7 arginosuccinase HT750_RS13485 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HT750_RS13500 ENOG4105DIJ Phosphoethanolamine transferase HT750_RS13505 ENOG4106R3P AraC family transcriptional regulator HT750_RS13510 ENOG4108XCZ PTS System HT750_RS13515 ENOG4108AHH pyruvate formate lyase II activase HT750_RS13525 ENOG4108YRF PTS System HT750_RS13530 ENOG4105DM4 PTS System HT750_RS13535 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HT750_RS13540 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HT750_RS13545 ENOG4105DCT glycerol dehydrogenase HT750_RS13550 ENOG4108XC3 NADH ubiquinone oxidoreductase HT750_RS13555 ENOG4108Q5Y Membrane HT750_RS13565 ENOG4105SYT Methylenetetrahydrofolate reductase HT750_RS13570 ENOG4105CGH 5'-nucleotidase HT750_RS13580 ENOG4105CGH 5'-nucleotidase HT750_RS13585 ENOG4105CGH 5'-nucleotidase HT750_RS13590 ENOG4105DRB nucleoside-specific channel-forming protein HT750_RS13595 ENOG4105CFH Aspartokinase HT750_RS13600 ENOG4105C28 cystathionine HT750_RS13610 ENOG4107S01 Repressor protein MetJ HT750_RS13620 ENOG4105C25 Primosomal protein n' HT750_RS13625 ENOG4105ETE Transcriptional regulator (LacI family HT750_RS13630 ENOG41063M6 Cell Division Protein HT750_RS13645 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HT750_RS13670 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HT750_RS13680 ENOG4105CBT Fructose-1,6-bisphosphatase HT750_RS13685 ENOG4105DP0 ferredoxin-NADP reductase HT750_RS13695 ENOG41065TG regulatoR HT750_RS13700 ENOG4108VTS Membrane HT750_RS13705 ENOG4105EBK exported protein HT750_RS13720 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HT750_RS13735 ENOG4105FMW periplasmic HT750_RS13740 ENOG4105E3W Two component transcriptional regulator (Winged helix family HT750_RS13745 ENOG4105E0F Histidine kinase HT750_RS13755 ENOG4108RPX mosc domain containing protein HT750_RS13765 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HT750_RS13775 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) HT750_RS13790 ENOG4105DKG l-rhamnose isomerase HT750_RS13810 ENOG41064BA PTS system, fructose-specific, IIA component HT750_RS13815 ENOG4105DM4 PTS System HT750_RS13820 ENOG4105CN9 Peptidase m42 family protein HT750_RS13825 ENOG4106C3V frv operon regulatory protein HT750_RS13830 ENOG4108V87 frv operon regulatory protein HT750_RS13840 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) HT750_RS13855 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HT750_RS13860 ENOG4108MG3 formate dehydrogenase HT750_RS13875 ENOG41068KX affects formate dehydrogenase-N HT750_RS13890 ENOG4105SUU thioesterase domain HT750_RS13905 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HT750_RS13910 ENOG4105E98 transcriptional regulator DeoR family HT750_RS13915 ENOG4108MGF sugar kinase HT750_RS13920 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HT750_RS13925 ENOG4105D2M Aldolase HT750_RS13930 ENOG4107QKS N-acylglucosamine 2-epimerase HT750_RS13935 ENOG4107WI4 Aldose-1-epimerase HT750_RS13940 ENOG4105CJQ hydrolase, family 31 HT750_RS13945 ENOG4105CT4 transporter HT750_RS13950 ENOG4105CT4 transporter HT750_RS13955 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is HT750_RS13960 ENOG4105R9B Major Facilitator HT750_RS13965 ENOG4108KHF Resistance protein HT750_RS13970 ENOG4108K85 Transcriptional regulator HT750_RS13975 ENOG4105VNT transposase (IS4 family) protein HT750_RS13980 ENOG4105CI3 gtp-binding protein typa HT750_RS13985 ENOG4105C5F glutamine synthetase HT750_RS13990 ENOG4105CUX Signal transduction histidine kinase HT750_RS13995 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HT750_RS14000 ENOG4106FIY HT750_RS14005 ENOG4105D4P Coproporphyrinogen iii oxidase HT750_RS14020 ENOG4105C2M dna polymerase I HT750_RS14025 ENOG4106HNH Acyl-transferase HT750_RS14035 ENOG4108Z33 Thiol disulfide Interchange Protein HT750_RS14040 ENOG4105E27 serine threonine protein kinase HT750_RS14045 ENOG4105PC1 Conserved Protein HT750_RS14050 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HT750_RS14055 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HT750_RS14085 ENOG4108RR8 protoporphyrinogen oxidase HT750_RS14090 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HT750_RS14095 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HT750_RS14115 ENOG4108EX3 reductase HT750_RS14120 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HT750_RS14125 ENOG4105MDZ Transcriptional activator rfaH HT750_RS14135 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HT750_RS14140 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HT750_RS14145 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HT750_RS14155 ENOG4105JC1 sterol-binding domain protein HT750_RS14165 ENOG4105CGY Dna recombination protein HT750_RS14170 ENOG4107HP6 Transcriptional regulator HT750_RS14175 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HT750_RS14180 ENOG4108RTU Aldolase HT750_RS14185 ENOG4105JN3 extra-cytoplasmic solute receptor family protein HT750_RS14200 ENOG4108I5U Uridine phosphorylase HT750_RS14205 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HT750_RS14210 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) HT750_RS14220 ENOG4107R1Q Membrane protein FdrA HT750_RS14225 ENOG4107REC cytoplasmic protein HT750_RS14230 ENOG4105C5B carbamate kinase HT750_RS14240 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HT750_RS14245 ENOG4105F52 Transcriptional regulator HT750_RS14255 ENOG4105DZ2 Transcriptional regulator HT750_RS14260 ENOG4105EMK carboxylate amino acid amine transporter HT750_RS14265 ENOG4105DQF Hydrolase HT750_RS14270 ENOG4108EUD Lysophospholipase HT750_RS14275 ENOG410829K Lysine exporter protein (Lyse ygga) HT750_RS14280 ENOG4105CCF Lysine exporter protein (Lyse ygga) HT750_RS14285 ENOG4105C9U ATP-dependent DNA helicase RecQ HT750_RS14290 ENOG4105HDD phospholipase HT750_RS14295 ENOG4108VUY thioesterase Superfamily protein HT750_RS14300 ENOG4105FR1 rard protein HT750_RS14315 ENOG4107QUT magnesium and cobalt transport protein CorA HT750_RS14320 ENOG4108T58 Mg2 transport protein CorA HT750_RS14325 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase HT750_RS14330 ENOG4105C4R Atp-dependent dna helicase HT750_RS14335 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HT750_RS14345 ENOG4105CT0 Protein of unknown function, DUF484 HT750_RS14355 ENOG4105S7Z (LipO)protein HT750_RS14375 ENOG4107T0K Adenylate cyclase HT750_RS14385 ENOG41076E6 Uroporphyrinogen-III Synthase HT750_RS14390 ENOG4105ECF c-methyltransferase HT750_RS14395 ENOG410601J HemY protein HT750_RS14400 ENOG4105ENH Sulfatase HT750_RS14405 ENOG4105C4X radical SAM domain protein HT750_RS14430 ENOG4105C85 amino acid HT750_RS14450 ENOG4105EGZ biosynthesis protein HT750_RS14455 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HT750_RS14460 ENOG4108WJ1 acetyltransferase HT750_RS14465 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HT750_RS14470 ENOG4105C1B dTDP-glucose 4-6-dehydratase HT750_RS14475 ENOG4107QQG Dehydrogenase HT750_RS14480 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HT750_RS14485 ENOG4105SFE lipopolysaccharide biosynthesis protein HT750_RS14490 ENOG4105ESV Glycosyl transferase, family 4 HT750_RS14495 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HT750_RS14520 ENOG4105C4R Atp-dependent dna helicase HT750_RS14530 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HT750_RS14540 ENOG4105EMY transcriptional regulator HT750_RS14545 ENOG4105C7B Threonine dehydratase HT750_RS14555 ENOG4105CM2 brancheD-chain amino acid aminotransferase HT750_RS14560 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HT750_RS14580 ENOG4105C0P Mg chelatase subunit ChlI HT750_RS14585 ENOG4108WFC UPF0438 protein yifE HT750_RS14625 ENOG4107EJG GntR family transcriptional regulator HT750_RS14630 ENOG4105C0R drug resistance transporter emrb qaca subfamily HT750_RS14635 ENOG4105ETE Transcriptional regulator (LacI family HT750_RS14640 ENOG4108RVA ribokinase HT750_RS14645 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HT750_RS14650 ENOG4105CNN ABC, transporter HT750_RS14655 ENOG4105C2J ABC transporter HT750_RS14685 ENOG4108VVK transcriptional Regulator, AsnC HT750_RS14690 ENOG4105QTB Flavodoxin HT750_RS14705 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HT750_RS14755 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HT750_RS14760 ENOG4108RQP Major type 1 subunit fimbrin HT750_RS14770 ENOG4105CW0 outer membrane usher protein HT750_RS14780 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HT750_RS14785 ENOG4105C8U phosphate abc transporter HT750_RS14790 ENOG4105E2Z phosphate ABC transporter (Permease HT750_RS14795 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HT750_RS14800 ENOG4108UTW Plays a role in the regulation of phosphate uptake HT750_RS14830 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HT750_RS14835 ENOG4105C7N Xanthine uracil vitamin C permease HT750_RS14840 ENOG4108YYH Nadph-dependent fmn reductase HT750_RS14845 ENOG4105E8Q phosphopantetheinyl transferase HT750_RS14850 ENOG4105G2Y Transcriptional regulator HT750_RS14860 ENOG4108P6C Tryptophan transporter of low affinity HT750_RS14895 ENOG4105VG0 50S ribosomal protein l34 HT750_RS14910 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HT750_RS14920 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HT750_RS14925 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HT750_RS14930 ENOG410667J hydrolase HT750_RS14935 ENOG410657R replicase EC 2.7 HT750_RS14940 ENOG4105EMF GntR family transcriptional regulator HT750_RS14945 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HT750_RS14950 ENOG4108RTU Aldolase HT750_RS14960 ENOG4105DJB Major Facilitator Superfamily HT750_RS14970 ENOG4105D99 atp gtp-binding protein HT750_RS14975 ENOG4105R2A (LipO)protein HT750_RS14995 ENOG4105FDP GntR family transcriptional regulator HT750_RS15000 ENOG4105CI1 PTS System HT750_RS15005 ENOG4105F8D glycoside hydrolase family 4 HT750_RS15010 ENOG4108AHD Transcriptional regulator HT750_RS15015 ENOG4107RUZ Sss sodium solute transporter superfamily HT750_RS15020 ENOG4105CBG Sulfatase HT750_RS15025 ENOG4105VG5 Membrane HT750_RS15030 ENOG4105JP4 Inner membrane protein yidG HT750_RS15035 ENOG4105J13 transcriptional regulator HT750_RS15040 ENOG4105E5M Multidrug resistance protein D HT750_RS15055 ENOG4105C7K acetolactate synthase HT750_RS15060 ENOG4105M71 acetolactate synthase 1 regulatory subunit HT750_RS15075 ENOG4108KX4 response regulator HT750_RS15080 ENOG4105BZU Histidine kinase HT750_RS15085 ENOG4105CXY transporter HT750_RS15090 ENOG4105CXY transporter HT750_RS15100 ENOG4105C7N Xanthine uracil vitamin C permease HT750_RS15105 ENOG4108SAJ Protein of unknown function (DUF1198) HT750_RS15130 ENOG4108YAB Invasion protein HT750_RS15135 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC HT750_RS15160 ENOG4105T8A Uncharacterized protein YicS HT750_RS15165 ENOG4105D01 (LipO)protein HT750_RS15170 ENOG4108UZ3 Transporter HT750_RS15175 ENOG4105S8Q sugar efflux transporter HT750_RS15190 ENOG4105CT4 transporter HT750_RS15195 ENOG4105CJQ hydrolase, family 31 HT750_RS15200 ENOG4105ETD TRANSCRIPTIONal HT750_RS15205 ENOG4105DM4 PTS System HT750_RS15210 ENOG4108YRF PTS System HT750_RS15215 ENOG4105DM4 PTS System HT750_RS15220 ENOG4105D2N Aldolase HT750_RS15230 ENOG4105DKQ ROK family HT750_RS15240 ENOG4105JV1 AsmA family HT750_RS15245 ENOG4105C2W permease HT750_RS15250 ENOG4105D6U Sodium Glutamate Symporter HT750_RS15255 ENOG4105CB5 ATP-dependent DNA helicase recG HT750_RS15260 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HT750_RS15265 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HT750_RS15275 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HT750_RS15285 ENOG4105EN6 Membrane HT750_RS15290 ENOG4105F5P DNA-damage-inducible protein d HT750_RS15400 ENOG4105DSJ YicC domain protein HT750_RS15420 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) HT750_RS15425 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HT750_RS15435 ENOG4105KDC 50s ribosomal protein l28 HT750_RS15455 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HT750_RS15460 ENOG4105DKP glycosyl transferase, family 9 HT750_RS15465 ENOG4107RJ7 Glycosyl transferase (Group 1 HT750_RS15470 ENOG4107543 (lipo)polysaccharide HT750_RS15475 ENOG4106AH0 Glycosyl Transferase HT750_RS15480 ENOG4105X1N Glycosyl transferase family 8 HT750_RS15490 ENOG4105X1N Glycosyl transferase family 8 HT750_RS15495 ENOG4105K64 Glycosyl transferase, family 2 HT750_RS15500 ENOG41068PG O-Antigen polymerase HT750_RS15505 ENOG4105D16 lipopolysaccharide heptosyltransferase i HT750_RS15510 ENOG4105XA0 heptosyltransferase ii HT750_RS15520 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HT750_RS15530 ENOG4105K64 Glycosyl transferase, family 2 HT750_RS15535 ENOG4105PXI polysaccharide deacetylase HT750_RS15540 ENOG41063SB peptidase HT750_RS15550 ENOG4107YZP Rhodanese domain protein HT750_RS15555 ENOG4105VW4 glutaredoxin 3 HT750_RS15570 ENOG4105D7W serine acetyltransferase HT750_RS15575 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HT750_RS15585 ENOG41073TP transcriptional regulator HT750_RS15590 ENOG4105DAA L-lactate HT750_RS15600 ENOG4108WY4 inner membrane lipoprotein HT750_RS15605 ENOG4108YYI Protein of unknown function (DUF2810) HT750_RS15610 ENOG41060ND LF82 chromosome, complete sequence HT750_RS15615 ENOG4105E61 Mannitol repressor protein HT750_RS15625 ENOG4105CTS PTS system mannitol-specific HT750_RS15630 ENOG4105FP6 Protein of unknown function (DUF3302) HT750_RS15635 ENOG4105EFX secretion protein, HlyD family HT750_RS15680 ENOG4108BMY protease HT750_RS15685 ENOG4108U78 Glutathione S-transferase HT750_RS15695 ENOG4105EM7 Selenocysteine-specific translation elongation factor HT750_RS15700 ENOG4105C0A alcohol dehydrogenase HT750_RS15710 ENOG4105C26 Dehydrogenase HT750_RS15725 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin HT750_RS15735 ENOG4105CT4 transporter HT750_RS15745 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HT750_RS15750 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HT750_RS15755 ENOG4105H6Q decarboxylase HT750_RS15760 ENOG4105CMG Carbohydrate kinase HT750_RS15765 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HT750_RS15770 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HT750_RS15775 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HT750_RS15780 ENOG4108R66 Conserved Protein HT750_RS15790 ENOG4105J4Q Transcriptional regulator HT750_RS15795 ENOG4108XIB electron transport protein ysaA HT750_RS15800 ENOG4105JKW Valine--pyruvate aminotransferase HT750_RS15805 ENOG4107T9C Alpha amylase catalytic region HT750_RS15810 ENOG4108UR8 BAX protein HT750_RS15815 ENOG4105T16 Transcriptional regulator (AraC family) HT750_RS15820 ENOG4108HWW ABC transporter HT750_RS15825 ENOG4105C2J ABC transporter HT750_RS15830 ENOG4105DFW ABC transporter HT750_RS15840 ENOG4105CMG Carbohydrate kinase HT750_RS15845 ENOG410688U Inner membrane protein yiaB HT750_RS15850 ENOG4108Z12 YiaAB two helix domain-containing protein HT750_RS15855 ENOG4105MEV Acyl-transferase HT750_RS15880 ENOG41060TC Hok gef cell toxic protein HT750_RS15890 ENOG4105MVF Transcriptional regulator HT750_RS15895 ENOG4106JH6 (LipO)protein HT750_RS15905 ENOG4108ZG0 Ompa motb domain protein HT750_RS15910 ENOG4107QY8 reductase HT750_RS15915 ENOG4105HNP -acetyltransferase HT750_RS15920 ENOG4108R3E Dna-3-methyladenine glycosylase i HT750_RS15925 ENOG4105EAX Putative lipase HT750_RS15930 ENOG4105FCD Major Facilitator HT750_RS15935 ENOG4105DIJ Phosphoethanolamine transferase HT750_RS15945 ENOG4105DEF Extracellular solute-binding protein, family 5 HT750_RS15950 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HT750_RS15955 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HT750_RS15960 ENOG4105C3U ABC transporter HT750_RS15965 ENOG4108JQ7 (ABC) transporter HT750_RS15970 ENOG4105C44 Serine transporter HT750_RS15985 ENOG4105D1V cellulose synthase operon protein YhjU HT750_RS15990 ENOG4105WQA Cellulose biosynthesis protein BcsF HT750_RS15995 ENOG4105U74 cellulose biosynthesis protein BcsE HT750_RS16000 ENOG410661M cytoplasmic protein HT750_RS16010 ENOG4107QZ7 Cellulose synthase catalytic subunit HT750_RS16015 ENOG4107EEX Cellulose synthase regulator protein HT750_RS16020 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HT750_RS16025 ENOG4105EJG cellulose synthase HT750_RS16030 ENOG4105BZU Histidine kinase HT750_RS16040 ENOG4105CS0 peptidase HT750_RS16045 ENOG4107SS6 2-dehydro-3-deoxygluconokinase HT750_RS16050 ENOG4105CMB EAL domain-containing protein HT750_RS16055 ENOG41066T0 asmA family HT750_RS16060 ENOG4105CSH Transporter HT750_RS16065 ENOG4107H3J ribonuclease HT750_RS16070 ENOG4105CBN LysR family transcriptional regulator HT750_RS16075 ENOG4106S2D Transcriptional regulator HT750_RS16085 ENOG4105CA0 peroxidase HT750_RS16090 ENOG4105CVK Glutamate decarboxylase HT750_RS16115 ENOG4105BZS acriflavin resistance protein HT750_RS16120 ENOG4105C1P efflux transporter, rnd family, mfp subunit HT750_RS16130 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HT750_RS16135 ENOG4108YK4 Acid-resistance membrane protein HT750_RS16140 ENOG41060V2 Acid-resistance protein HT750_RS16145 ENOG4105XXV Acid-resistance protein HT750_RS16150 ENOG4105KT7 mgtC SapB transporter HT750_RS16155 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) HT750_RS16160 ENOG4105EHG Permease protein HT750_RS16170 ENOG41090JE Utilization Protein HT750_RS16175 ENOG4105D4P Coproporphyrinogen iii oxidase HT750_RS16185 ENOG4107ENK receptor HT750_RS16190 ENOG4106QJH hemin transport protein HT750_RS16200 ENOG4105Y4Z Outer Membrane Lipoprotein HT750_RS16220 ENOG4105K89 arsenate reductase HT750_RS16225 ENOG4107R5R arsenical pump membrane protein HT750_RS16230 ENOG4105KBH arsR family transcriptional regulator HT750_RS16240 ENOG4105DC8 reductase HT750_RS16245 ENOG4105D6S protein involved in catabolism of external DNA HT750_RS16250 ENOG4105DGW oligopeptidase A HT750_RS16260 ENOG4105DUX Transporter HT750_RS16275 ENOG4105CJ3 phosphate transporter HT750_RS16280 ENOG4105CBX hi0933 family HT750_RS16285 ENOG4107UNS conserved inner membrane protein HT750_RS16300 ENOG4105D0S secretion protein (HlyD HT750_RS16305 ENOG4105CJ1 ABC, transporter HT750_RS16310 ENOG4105CMI transporter HT750_RS16330 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HT750_RS16335 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HT750_RS16340 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HT750_RS16345 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HT750_RS16350 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HT750_RS16355 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HT750_RS16360 ENOG4105DSF transport protein HT750_RS16365 ENOG4105F9N Major Facilitator Superfamily HT750_RS16370 ENOG4108W1V Lipoprotein HT750_RS16375 ENOG4105EX9 Membrane HT750_RS16395 ENOG4107FS9 Membrane HT750_RS16405 ENOG4105MG3 Membrane HT750_RS16410 ENOG4106H78 methyltransferase HT750_RS16415 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HT750_RS16420 ENOG4105CAK Cell division ATP-binding protein ftsE HT750_RS16425 ENOG4105CRP Part of the ABC transporter FtsEX involved in HT750_RS16430 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HT750_RS16435 ENOG4105CP9 extracellular ligand-binding receptor HT750_RS16440 ENOG4105U59 -acetyltransferase HT750_RS16445 ENOG4105CP9 extracellular ligand-binding receptor HT750_RS16450 ENOG4105C32 Amino acid ABC transporter (Permease) HT750_RS16455 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HT750_RS16460 ENOG4105C0Z ABC transporter HT750_RS16465 ENOG4108IV0 ABC, transporter HT750_RS16470 ENOG4105BZ7 extracellular solute-binding protein family 1 HT750_RS16475 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component HT750_RS16480 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component HT750_RS16485 ENOG4108IJ9 (ABC) transporter HT750_RS16490 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HT750_RS16495 ENOG4105WC8 Conserved Protein HT750_RS16500 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HT750_RS16520 ENOG4105GMB type VI secretion system effector, hcp1 family HT750_RS16525 ENOG4105WCN acetyltransferase HT750_RS16530 ENOG4105D9R oxidoreductase HT750_RS16535 ENOG4105C2I pirin domain protein HT750_RS16540 ENOG4105DIQ Transcriptional regulator HT750_RS16545 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HT750_RS16550 ENOG4105C6Z Gluconate HT750_RS16555 ENOG4105C9U ATP-dependent DNA helicase RecQ HT750_RS16565 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HT750_RS16570 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HT750_RS16575 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) HT750_RS16595 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HT750_RS16615 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HT750_RS16630 ENOG4105E98 transcriptional regulator DeoR family HT750_RS16635 ENOG4105CYB regulatoR HT750_RS16640 ENOG4105E0Y RtcB Protein HT750_RS16655 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HT750_RS16660 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HT750_RS16665 ENOG4105C6Z Gluconate HT750_RS16675 ENOG4105MJ2 Competence protein HT750_RS16685 ENOG4105DNE Transposase HT750_RS16695 ENOG4105CE1 Ferrous iron transport protein b HT750_RS16700 ENOG4105XFK Ferrous iron transport protein A HT750_RS16705 ENOG4105BZM domain protein HT750_RS16710 ENOG4108RRZ Transcription elongation factor GreB HT750_RS16720 ENOG4105E0F Histidine kinase HT750_RS16740 ENOG4108MAJ Membrane HT750_RS16750 ENOG4105VEJ Heat shock protein HT750_RS16755 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HT750_RS16760 ENOG4105DQY intracellular growth attenuator HT750_RS16765 ENOG4107RK2 ADP-ribose diphosphatase NudE HT750_RS16770 ENOG4108JQC penicillin-binding protein 1A HT750_RS16775 ENOG4108U1Q Pilus assembly protein HT750_RS16780 ENOG41065NF Fimbrial assembly family protein HT750_RS16785 ENOG4105XPX DNA utilization protein HofO HT750_RS16790 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HT750_RS16795 ENOG4105E4G Type IV pilus HT750_RS16810 ENOG4105EGB membrane protein DamX HT750_RS16815 ENOG4105DFE Dna adenine methylase HT750_RS16820 ENOG4105DJV ribulose-phosphate 3-epimerase HT750_RS16825 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HT750_RS16830 ENOG4105C31 Tryptophanyl-tRNA synthetase HT750_RS16835 ENOG4108M21 HT750_RS16840 ENOG4105RMW regulation of transcription, DNA-dependent HT750_RS16845 ENOG4108626 Racemase HT750_RS16850 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HT750_RS16855 ENOG41080QX K07048 phosphotriesterase-related protein HT750_RS16860 ENOG4105MUZ Protein of unknown function DUF2620 HT750_RS16865 ENOG4106M0N transport system permease protein HT750_RS16870 ENOG4106PKC pyridoxal phosphate binding HT750_RS16875 ENOG4105VYH HT750_RS16885 ENOG4107V9H nitrite transporter HT750_RS16890 ENOG4105WZK nitrite reductase NADPH small subunit HT750_RS16895 ENOG4107QZF nitrite reductase NADPH large subunit HT750_RS16905 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HT750_RS16915 ENOG4105MZU cell filamentation protein HT750_RS16920 ENOG4105DDQ anthranilate synthase HT750_RS16925 ENOG4105C8Y Acetylornithine aminotransferase HT750_RS16930 ENOG410613R integral membrane protein, YccS YhfK family HT750_RS16940 ENOG4108UKZ OsmC family HT750_RS16945 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HT750_RS16955 ENOG4105DNZ Alpha Beta Hydrolase HT750_RS16960 ENOG4105C5H ABC transporter HT750_RS16975 ENOG4105VKU nucleicacid-binding protein HT750_RS16980 ENOG4108YZY peptidylprolyl cis-trans isomerase HT750_RS16990 ENOG4108V1T peptidylprolyl cis-trans isomerase HT750_RS16995 ENOG4105WWK YheO domain protein HT750_RS17005 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) HT750_RS17035 ENOG4105W53 bacterioferritin-associated ferredoxin HT750_RS17040 ENOG4108UQY Iron-storage protein HT750_RS17065 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HT750_RS17110 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) HT750_RS17155 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HT750_RS17160 ENOG41067V7 50S ribosomal protein L36 HT750_RS17190 ENOG4105VTS DnaJ-like, subfamily C HT750_RS17195 ENOG4105W1Y Transcriptional regulator HT750_RS17200 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HT750_RS17210 ENOG4105C1A potassium transporter peripheral membrane HT750_RS17230 ENOG4105C79 DNA protecting protein DprA HT750_RS17240 ENOG4108WI1 Dna topoisomerase HT750_RS17255 ENOG4105SG3 Protein of unknown function (DUF1488) HT750_RS17260 ENOG4108Z0R Transferase HT750_RS17300 ENOG4105CDA abc transporter atp-binding protein HT750_RS17305 ENOG4105DRP amino acid AbC transporter HT750_RS17310 ENOG4105EZ7 amino acid ABC transporter HT750_RS17320 ENOG4105XCM membrane LIPOPROTEIN HT750_RS17325 ENOG4105BZS acriflavin resistance protein HT750_RS17330 ENOG4105C1P efflux transporter, rnd family, mfp subunit HT750_RS17335 ENOG4108XG4 DNA-binding transcriptional regulator HT750_RS17340 ENOG41061ME transport protein HT750_RS17345 ENOG4105CEC DNA methylase N-4 N-6 HT750_RS17355 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HT750_RS17365 ENOG4108IA2 Sodium pantothenate symporter HT750_RS17370 ENOG4105RG0 Membrane HT750_RS17375 ENOG4107UEK pfkb domain protein HT750_RS17380 ENOG4105E98 transcriptional regulator DeoR family HT750_RS17385 ENOG4105D2N Aldolase HT750_RS17390 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HT750_RS17395 ENOG4105C2J ABC transporter HT750_RS17400 ENOG4105CNN ABC, transporter HT750_RS17405 ENOG4107UEK pfkb domain protein HT750_RS17415 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HT750_RS17420 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HT750_RS17425 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HT750_RS17430 ENOG41062P1 Diguanylate cyclase phosphodiesterase HT750_RS17440 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HT750_RS17445 ENOG4105VQ7 Rod shape-determining protein MreD HT750_RS17455 ENOG4105C03 ribonuclease HT750_RS17460 ENOG4105QD6 exported protein HT750_RS17465 ENOG4105D1U peptidase U62 modulator of DNA gyrase HT750_RS17470 ENOG4105CR8 Transcriptional regulator HT750_RS17475 ENOG4105ZQC membrane protein AaeX HT750_RS17490 ENOG4105UNR (Barnase) inhibitor HT750_RS17495 ENOG4105RID UPF0379 protein yhcN HT750_RS17510 ENOG4105C0H protease HT750_RS17515 ENOG4105C0H protease HT750_RS17520 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HT750_RS17525 ENOG4105D6Z AFG1 family ATPase HT750_RS17545 ENOG4107MKT Stringent starvation protein a HT750_RS17550 ENOG4105KB2 stringent starvation protein b HT750_RS17555 ENOG4105CEE C4-dicarboxylate transporter HT750_RS17585 ENOG4108R66 Conserved Protein HT750_RS17590 ENOG4105DFS Conserved Protein HT750_RS17595 ENOG4105BZ8 glutamate synthase HT750_RS17600 ENOG4105CBC glutamate synthase HT750_RS17605 ENOG4105N5T Radical SAM Protein HT750_RS17610 ENOG4105BZU Histidine kinase HT750_RS17615 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HT750_RS17625 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HT750_RS17630 ENOG41080Z8 PHOSPHOCARRIER protein HT750_RS17640 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HT750_RS17645 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HT750_RS17650 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HT750_RS17655 ENOG4108IUZ ABC transporter HT750_RS17660 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HT750_RS17665 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HT750_RS17675 ENOG4105C2X Arabinose 5-phosphate isomerase HT750_RS17680 ENOG4105FEU K -dependent Na -Ca exchanger HT750_RS17685 ENOG4105DHJ ABC, transporter HT750_RS17690 ENOG4105CY3 ABC transporter, permease HT750_RS17695 ENOG4107PE3 Mammalian cell entry related domain protein HT750_RS17700 ENOG4105E3I toluene tolerance HT750_RS17705 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HT750_RS17710 ENOG4105VFK BolA family HT750_RS17720 ENOG4105HVQ Regulatory factor of maltose metabolism HT750_RS17725 ENOG4105EAH synthase HT750_RS17740 ENOG4105QYV Membrane HT750_RS17750 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HT750_RS17755 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HT750_RS17760 ENOG4105HBR Rna-binding protein HT750_RS17770 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HT750_RS17775 ENOG4105EEI dihydropteroate synthase HT750_RS17785 ENOG4105NTZ Preprotein translocase subunit SecG HT750_RS17795 ENOG4105DIJ Phosphoethanolamine transferase HT750_RS17815 ENOG4105CHV Transcription elongation factor NusA HT750_RS17855 ENOG4105C1J atp-dependent rna helicase HT750_RS17860 ENOG4105CIC tryptophan-specific transport protein HT750_RS17865 ENOG4105DEN Luciferase family HT750_RS17885 ENOG4108YYD acetyltransferase HT750_RS17900 ENOG4107R7Y intracellular protease Pfpi family HT750_RS17905 ENOG4105K4T epimerase HT750_RS17910 ENOG4107S21 permease HT750_RS17915 ENOG4105W4M Transport-associated protein HT750_RS17935 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HT750_RS17940 ENOG4106HBN Galactosamine-6-phosphate isomerase HT750_RS17945 ENOG4105F3R pts system mannose fructose sorbose family iid HT750_RS17950 ENOG4105ETZ PTS System HT750_RS17955 ENOG4108UZY PTS System HT750_RS17965 ENOG4105E70 isomerase HT750_RS17970 ENOG4105CE4 GlcNAc 6-P deacetylase HT750_RS17975 ENOG4108YTN IIa component HT750_RS17980 ENOG4105F3R pts system mannose fructose sorbose family iid HT750_RS17990 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HT750_RS18000 ENOG4105E98 transcriptional regulator DeoR family HT750_RS18005 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression HT750_RS18010 ENOG4105ZEG Suppressor protein HT750_RS18015 ENOG4105CTX dehydratase HT750_RS18020 ENOG4105DJB Major Facilitator Superfamily HT750_RS18030 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HT750_RS18035 ENOG4105BZW Glycerate kinase HT750_RS18060 ENOG410811B TRANSCRIPTIONal HT750_RS18065 ENOG4105C7B Threonine dehydratase HT750_RS18070 ENOG4108MST Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity) HT750_RS18075 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HT750_RS18080 ENOG4105C6N Formate acetyltransferase HT750_RS18085 ENOG4105KME endoribonuclease L-psp HT750_RS18090 ENOG4105EJQ L-serine dehydratase HT750_RS18095 ENOG4105C44 Serine transporter HT750_RS18105 ENOG4106D80 Uncharacterized protein YhaL HT750_RS18110 ENOG4108CNN domain protein HT750_RS18115 ENOG4105CWB LysR family transcriptional Regulator HT750_RS18120 ENOG4105KAF membrAne HT750_RS18125 ENOG4105KAF membrAne HT750_RS18130 ENOG4105CHF Glutathione S-transferase HT750_RS18135 ENOG4108VBZ doxx family HT750_RS18140 ENOG4105YJD HT750_RS18145 ENOG41090KG Inner membrane protein YqjE HT750_RS18150 ENOG4105NE1 Conserved Protein HT750_RS18155 ENOG4105WAY exported protein HT750_RS18160 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HT750_RS18165 ENOG4106W5V Membrane HT750_RS18170 ENOG4107YCY Transcriptional regulator HT750_RS18195 ENOG4105DPW Major facilitator superfamily MFS_1 HT750_RS18205 ENOG4105CTX dehydratase HT750_RS18210 ENOG4105P66 Membrane HT750_RS18215 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) HT750_RS18220 ENOG4105DU1 integral membrane protein, terc HT750_RS18225 ENOG4105EE0 oxidoreductase HT750_RS18230 ENOG4108UB4 uncharacterized protein ygjQ HT750_RS18235 ENOG4108VKG metal-dependent hydrolase HT750_RS18245 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HT750_RS18250 ENOG4107WCA isomerase HT750_RS18255 ENOG4107W6W Conserved Protein HT750_RS18260 ENOG4105E5D amino acid HT750_RS18265 ENOG4105FK9 beta-D-galactosidase beta subunit HT750_RS18270 ENOG4105CNT hydrolase family 2 HT750_RS18275 ENOG4105CQ4 Transcriptional regulator HT750_RS18280 ENOG4108Y51 tRNA-binding protein HT750_RS18290 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HT750_RS18295 ENOG4105NTW Transcriptional regulator HT750_RS18300 ENOG4105Q26 Siderophore-interacting protein HT750_RS18330 ENOG410693A DNA-binding protein HT750_RS18335 ENOG4105JXR Protein of unknown function (DUF3296) HT750_RS18370 ENOG4107QY8 reductase HT750_RS18375 ENOG4105QAX Iron-sulfur HT750_RS18380 ENOG4107KGK dmso reductase anchor subunit HT750_RS18385 ENOG4108NEM leader-binding protein dmsD HT750_RS18395 ENOG4105F2I Transposase HT750_RS18420 ENOG4105F4K antigen 43 HT750_RS18425 ENOG4106H6R UPF0380 protein HT750_RS18430 ENOG4105MFG Antirestriction protein HT750_RS18435 ENOG4108YGG dna repair protein HT750_RS18445 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HT750_RS18480 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HT750_RS18485 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HT750_RS18500 ENOG4107QPK )-transporter HT750_RS18505 ENOG4107GFK fumarate HT750_RS18510 ENOG4106DSS Tartrate dehydratase subunit alpha HT750_RS18515 ENOG4105EJC lysr family transcriptional regulator HT750_RS18525 ENOG4107ZVW dihydroneopterin aldolase HT750_RS18540 ENOG4106MWK domain protein HT750_RS18545 ENOG4105I7R Adenylate cyclase HT750_RS18565 ENOG4107S78 Band 7 protein HT750_RS18570 ENOG4105PV3 Inner membrane protein yqiJ HT750_RS18580 ENOG4108MY7 Fimbrial HT750_RS18585 ENOG4108TTM chaperone HT750_RS18595 ENOG4105H8W Fimbrial protein HT750_RS18600 ENOG4105W0Z cytoplasmic protein HT750_RS18620 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HT750_RS18625 ENOG4106032 Glutathionylspermidine synthase HT750_RS18635 ENOG4105DFG type I secretion outer membrane protein HT750_RS18640 ENOG41087AY ADP-Ribose pyrophosphatase HT750_RS18645 ENOG4108SX3 cytoplasmic protein HT750_RS18650 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HT750_RS18655 ENOG4105IPS esterase HT750_RS18660 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HT750_RS18665 ENOG4105VRH Antibiotic biosynthesis monooxygenase HT750_RS18670 ENOG4105NF4 modulator of drug activity HT750_RS18675 ENOG4107DEU Inner membrane protein YgiZ HT750_RS18680 ENOG4105DHQ Histidine kinase HT750_RS18685 ENOG4105XJC Two component transcriptional regulator (Winged helix family HT750_RS18690 ENOG4105H4F exported protein HT750_RS18695 ENOG4105F4I Transcriptional regulator HT750_RS18700 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation HT750_RS18705 ENOG4105WJ3 XRE family Transcriptional regulator HT750_RS18710 ENOG4108J59 Extracellular solute-binding protein, family 5 HT750_RS18715 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HT750_RS18720 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HT750_RS18725 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HT750_RS18730 ENOG4105CCT upf0313 protein HT750_RS18740 ENOG4105ZKC Conserved Protein HT750_RS18745 ENOG4105CV8 reductase HT750_RS18750 ENOG4108I6A alcohol dehydrogenase HT750_RS18755 ENOG4105CF7 AraC family transcriptional regulator HT750_RS18760 ENOG4108K81 inner membrane protein YghB HT750_RS18765 ENOG4105C28 cystathionine HT750_RS18770 ENOG4105CWK Biopolymer transport protein, ExbB HT750_RS18775 ENOG4108ZZF transport protein (ExbD) HT750_RS18780 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HT750_RS18790 ENOG4105CPC Aldo Keto reductase HT750_RS18800 ENOG410900S Protein of unknown function (DUF2623) HT750_RS18805 ENOG4105E3S small subunit HT750_RS18810 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HT750_RS18815 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HT750_RS18820 ENOG4105DPX Hydrogenase, large subunit HT750_RS18825 ENOG4108USZ hydrogenase HT750_RS18830 ENOG4108WGS hydrogenase 2-specific chaperone HT750_RS18840 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HT750_RS18845 ENOG4105CYM Glutathione S-transferase HT750_RS18850 ENOG4106032 Glutathionylspermidine synthase HT750_RS18855 ENOG4105CJ3 phosphate transporter HT750_RS18860 ENOG4108GH0 ATP-binding protein yghT HT750_RS18865 ENOG4108NDC ATP-binding protein yghS HT750_RS18870 ENOG4106FPV ATP-binding protein YghR HT750_RS18875 ENOG4108S55 polysaccharide biosynthesis protein HT750_RS18885 ENOG4108UUE Transcriptional regulator HT750_RS18890 ENOG4108M8S permease YjgP YjgQ family protein HT750_RS18900 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HT750_RS18905 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HT750_RS18925 ENOG4108KWP DNA-binding transcriptional regulator GlcC HT750_RS18930 ENOG4105CQB FAD linked oxidase domain protein HT750_RS18935 ENOG4105EU8 FAD linked oxidase domain protein HT750_RS18940 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HT750_RS18945 ENOG4108ZJF Glcg protein HT750_RS18950 ENOG4107QP3 malate synthase g HT750_RS18955 ENOG4105DAA L-lactate HT750_RS18970 ENOG4105U1E general secretion pathway protein M HT750_RS18995 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HT750_RS19005 ENOG4108YGG dna repair protein HT750_RS19010 ENOG4106549 Antirestriction protein HT750_RS19015 ENOG4106H6R UPF0380 protein HT750_RS19030 ENOG4105TS0 gtp-binding protein HT750_RS19120 ENOG4108R0M Aminoglycoside HT750_RS19185 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein HT750_RS19220 ENOG4107SCJ type I restriction enzyme EcoKI subunit R HT750_RS19235 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) HT750_RS19250 ENOG4105T40 surface antigen msp4 family protein HT750_RS19310 ENOG4107R1I NAD-dependent malic enzyme HT750_RS19315 ENOG4105CEE C4-dicarboxylate transporter HT750_RS19325 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase HT750_RS19350 ENOG4105BZ7 extracellular solute-binding protein family 1 HT750_RS19400 ENOG4105DFP Integrase HT750_RS19410 ENOG4108UQV Membrane HT750_RS19415 ENOG4105CXN decarboxylase HT750_RS19420 ENOG4105EAA nucleoside HT750_RS19435 ENOG4105CEN a g-specific adenine glycosylase HT750_RS19445 ENOG41090ED Protein with unknown function (DUF469) HT750_RS19450 ENOG4105K33 Periplasmic Protein HT750_RS19455 ENOG4105HDK L-asparaginase HT750_RS19460 ENOG4106MH3 alpha helix chain HT750_RS19465 ENOG4105CSA Coproporphyrinogen iii oxidase HT750_RS19470 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HT750_RS19480 ENOG4108VIA integral membrane protein HT750_RS19485 ENOG4105DFA alanine racemase domain protein HT750_RS19490 ENOG4105CZX twitching motility protein HT750_RS19505 ENOG4105D7Z glutathione synthase HT750_RS19510 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HT750_RS19515 ENOG4105RWS endonuclease I HT750_RS19525 ENOG4107QNK )-transporter HT750_RS19545 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HT750_RS19555 ENOG4108K0D peptidase, M48 HT750_RS19560 ENOG4105CV1 Transketolase (EC 2.2.1.1) HT750_RS19570 ENOG4105CTS PTS system mannitol-specific HT750_RS19575 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HT750_RS19580 ENOG4108Q8A Fructose-1,6-bisphosphatase HT750_RS19585 ENOG4108R4K DNA-binding, transcriptional regulator HT750_RS19590 ENOG4107Z1W Fructose transport system kinase HT750_RS19605 ENOG4105D2N Aldolase HT750_RS19610 ENOG4105D64 Mechanosensitive ion channel HT750_RS19615 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HT750_RS19620 ENOG4105MPN Membrane HT750_RS19625 ENOG4105DEQ transcriptional regulator HT750_RS19630 ENOG4105CYC Transferase HT750_RS19635 ENOG4108M7F enoyl-CoA hydratase isomerase HT750_RS19640 ENOG4105DJT lAO AO transport system ATPase HT750_RS19645 ENOG4105D5P Methylmalonyl-coA mutase HT750_RS19665 ENOG4108JQ1 Dehydrogenase HT750_RS19675 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HT750_RS19695 ENOG4107RAQ aminopeptidase HT750_RS19700 ENOG4105D0A hydroxylase HT750_RS19705 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HT750_RS19730 ENOG4105CS2 ec 3.2.1.21 HT750_RS19735 ENOG4105N5Z UPF0267 protein HT750_RS19740 ENOG4108UT2 hemolysin iii HT750_RS19750 ENOG4105Y75 tpr repeat protein HT750_RS19755 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HT750_RS19760 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HT750_RS19765 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HT750_RS19770 ENOG4105T95 Thiol disulfide interChange protein HT750_RS19775 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HT750_RS19785 ENOG4105CRK lysyL-tRNA synthetase HT750_RS19800 ENOG4105C2W permease HT750_RS19805 ENOG4105BZ8 glutamate synthase HT750_RS19810 ENOG4108R8B oxidoreductase Fe-S subunit HT750_RS19815 ENOG4105C7N Xanthine uracil vitamin C permease HT750_RS19820 ENOG4107QUY Guanine deaminase HT750_RS19825 ENOG4105C2W permease HT750_RS19830 ENOG4105C7W Xanthine dehydrogenase HT750_RS19835 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HT750_RS19840 ENOG4107UUR Chlorohydrolase aminohydrolase HT750_RS19845 ENOG4105BZ8 glutamate synthase HT750_RS19850 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HT750_RS19855 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HT750_RS19860 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HT750_RS19865 ENOG4105C5B carbamate kinase HT750_RS19875 ENOG4107S4Y M20 DapE family protein YgeY HT750_RS19880 ENOG4107RCH Diaminopropionate ammonia-lyase HT750_RS19885 ENOG4105IW6 Carbamoyltransferase HT750_RS19890 ENOG4108JUB Transcriptional regulator HT750_RS19895 ENOG4108UTP (2Fe-2S)-binding domain protein HT750_RS19900 ENOG4108HR6 Dehydrogenase HT750_RS19905 ENOG4105C7W Xanthine dehydrogenase HT750_RS19910 ENOG4108K5P (LipO)protein HT750_RS19920 ENOG4108MHD transport protein HT750_RS19925 ENOG4105CHU acetyl-coa acetyltransferase HT750_RS19935 ENOG4105CHR reductase HT750_RS19940 ENOG4107QNK )-transporter HT750_RS19950 ENOG4105RQF LysR family Transcriptional regulator HT750_RS19960 ENOG41060NJ transcriptional regulator HT750_RS19975 ENOG4105CPC Aldo Keto reductase HT750_RS19980 ENOG4105SUV lipoprotein YgdR HT750_RS19985 ENOG4105EE5 Membrane protein terC HT750_RS20000 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HT750_RS20015 ENOG4105IPU prepilin peptidase dependent protein A HT750_RS20020 ENOG4105JCS prepilin peptidase dependent protein HT750_RS20025 ENOG4105SEN Protein of unknown function (DUF2509) HT750_RS20030 ENOG4105RVB Prepilin peptidase dependent protein c HT750_RS20035 ENOG4105DSY exodeoxyribonuclease V, gamma HT750_RS20040 ENOG4107QXK peptidase HT750_RS20045 ENOG4107QKA exodeoxyribonuclease V beta HT750_RS20050 ENOG4107QYX exodeoxyribonuclease v alpha HT750_RS20055 ENOG4108EKC n-acetylglutamate synthase HT750_RS20060 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HT750_RS20065 ENOG4105CID antiterminator HT750_RS20070 ENOG4105CI1 PTS System HT750_RS20075 ENOG4105C87 Aminotransferase class I and II HT750_RS20080 ENOG4105C2X Arabinose 5-phosphate isomerase HT750_RS20105 ENOG4105CA3 membrane-bound lytic murein transglycosylase HT750_RS20110 ENOG4105CUZ uba thif-type nad fad binding protein HT750_RS20115 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HT750_RS20120 ENOG4105C9B Cysteine desulfurase HT750_RS20125 ENOG4105M5B (LipO)protein HT750_RS20130 ENOG4105ETT transcriptional Regulator, LysR family HT750_RS20135 ENOG4105M08 Membrane HT750_RS20145 ENOG4107EDW L-fucose operon activator HT750_RS20155 ENOG4105CMG Carbohydrate kinase HT750_RS20160 ENOG4105EHF Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity) HT750_RS20165 ENOG4105EDR glucose galactose transporter HT750_RS20170 ENOG4107W7X Aldolase HT750_RS20175 ENOG4105C0A alcohol dehydrogenase HT750_RS20185 ENOG4105EJQ L-serine dehydratase HT750_RS20190 ENOG4105C44 Serine transporter HT750_RS20195 ENOG4105EWT decarboxylase family HT750_RS20210 ENOG4105WP7 tRNA pseudouridine synthase C HT750_RS20215 ENOG4105DR9 pseudouridine synthase HT750_RS20220 ENOG4105QDK Flavodoxin HT750_RS20225 ENOG4105DJB Major Facilitator Superfamily HT750_RS20230 ENOG4105EQX glucarate dehydratase HT750_RS20235 ENOG4105EQX glucarate dehydratase HT750_RS20240 ENOG4105BZU Histidine kinase HT750_RS20245 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) HT750_RS20250 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HT750_RS20255 ENOG4106A2Z transcriptional regulator antitoxin, MazE HT750_RS20260 ENOG4105MZG transcriptional modulator of maze toxin, mazf HT750_RS20265 ENOG4105DXN mazG family HT750_RS20280 ENOG4105HA9 of methanol dehydrogenase type HT750_RS20290 ENOG4105HA9 of methanol dehydrogenase type HT750_RS20300 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HT750_RS20305 ENOG4105WBN Transcriptional regulator (LacI family HT750_RS20330 ENOG4108CWB sugar kinase ygcE HT750_RS20335 ENOG4108ITV Inner membrane protein yqcE HT750_RS20340 ENOG4105CHR reductase HT750_RS20345 ENOG4107R3A FAD linked oxidase domain protein HT750_RS20350 ENOG4105C54 Major Facilitator superfamily HT750_RS20355 ENOG4106IKH Electron transfer flavoprotein HT750_RS20360 ENOG4105YBM electron transfer flavoprotein subunit ygcQ HT750_RS20365 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator HT750_RS20370 ENOG4105WQV ferredoxin-like protein HT750_RS20375 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HT750_RS20380 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HT750_RS20395 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) HT750_RS20400 ENOG4107635 Hok Gef family protein HT750_RS20405 ENOG4108MXK alkaline phosphatase isozyme conversion HT750_RS20425 ENOG4105N0Z inner membrane protein ygbE HT750_RS20460 ENOG4108K5P (LipO)protein HT750_RS20465 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HT750_RS20475 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HT750_RS20480 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HT750_RS20485 ENOG4105KZM cytoplasmic protein HT750_RS20490 ENOG4105MEW serine threonine protein phosphatase HT750_RS20505 ENOG4105VXR cytoplasmic protein HT750_RS20515 ENOG4108JUA Transcriptional regulator HT750_RS20520 ENOG4105C45 hydrogenase expression formation protein (HypE) HT750_RS20525 ENOG4105CQS hydrogenase expression formation protein HypD HT750_RS20530 ENOG41083WG hydrogenase assembly chaperone HT750_RS20535 ENOG4107RSS Hydrogenase accessory protein HypB HT750_RS20540 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HT750_RS20545 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HT750_RS20550 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HT750_RS20555 ENOG4107R30 NADH dehydrogenase HT750_RS20560 ENOG4107TDF Formate hydrogenlyase subunit 4 HT750_RS20565 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HT750_RS20570 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HT750_RS20575 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HT750_RS20580 ENOG4105I6X formate hydrogenlyase maturation HT750_RS20585 ENOG4108MG9 hydrogenase 3 maturation protease HT750_RS20595 ENOG4105CS2 ec 3.2.1.21 HT750_RS20600 ENOG4105C5Y PTS System HT750_RS20605 ENOG4105DDV Transcriptional regulator (LacI family HT750_RS20610 ENOG4108RC0 Electron transport protein HT750_RS20615 ENOG4105C8H hydrogenase maturation protein Hypf HT750_RS20630 ENOG4108JUA Transcriptional regulator HT750_RS20640 ENOG410804X Transcriptional regulator HT750_RS20645 ENOG4105J92 DNA-binding transcriptional activator GutM HT750_RS20650 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HT750_RS20655 ENOG4105VI0 Pts system, glucitol sorbitol-specific HT750_RS20660 ENOG4105DZY Pts system, glucitol sorbitol-specific HT750_RS20665 ENOG410787A Pts system, glucitol sorbitol-specific HT750_RS20670 ENOG4105CVE Lytic murein transglycosylase HT750_RS20675 ENOG4107TH8 cina domain protein HT750_RS20695 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HT750_RS20725 ENOG4107VXZ Hydrolase HT750_RS20730 ENOG4105W39 Membrane HT750_RS20745 ENOG4105C0R drug resistance transporter emrb qaca subfamily HT750_RS20750 ENOG4105CW7 secretion protein, HlyD family HT750_RS20755 ENOG4105NTK Transcriptional repressor Mpra HT750_RS20760 ENOG4105ZED uncharacterized protein ygaH HT750_RS20765 ENOG4108UMN azlc family HT750_RS20775 ENOG4105GIJ Glycine betaine HT750_RS20780 ENOG4108HQS Glycine betaine HT750_RS20785 ENOG4108IJ7 Glycine betaine HT750_RS20790 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HT750_RS20795 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HT750_RS20805 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HT750_RS20810 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HT750_RS20815 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HT750_RS20820 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HT750_RS20825 ENOG4108WMJ Protein of unknown function (DUF2002) HT750_RS20830 ENOG4108RNS Exports L-alanine (By similarity) HT750_RS20835 ENOG4108X73 DNA- binding protein HT750_RS20840 ENOG4108V62 Rhodanese domain protein HT750_RS20845 ENOG41080HT Transcriptional regulator, arsr family HT750_RS20850 ENOG4105VPI YqaE family transport protein HT750_RS20855 ENOG4109066 lysm domain bon superfamily protein HT750_RS20860 ENOG4108PVQ transcriptional regulator HT750_RS20865 ENOG4105C85 amino acid HT750_RS20870 ENOG4108JPW Aminotransferase HT750_RS20875 ENOG4105C26 Dehydrogenase HT750_RS20880 ENOG4105D5U fad dependent oxidoreductase HT750_RS20890 ENOG4105E54 alpha-amylase HT750_RS20915 ENOG4108MGN ATP-binding component of a transport system HT750_RS20930 ENOG4108Z1B Cyclase dehydrase HT750_RS20940 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HT750_RS20945 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HT750_RS20960 ENOG4108JU6 CBS domain protein HT750_RS20965 ENOG4106KVJ cytochrome C assembly protein HT750_RS20970 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HT750_RS20995 ENOG41090EK ompa motb domain protein HT750_RS21000 ENOG4108KHX Diguanylate cyclase HT750_RS21005 ENOG4108WS1 HT750_RS21010 ENOG4105QP9 Protein of unknown function (DUF2799) HT750_RS21015 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HT750_RS21020 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HT750_RS21025 ENOG4105CQC Prephenate dehydratase HT750_RS21035 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HT750_RS21040 ENOG4105VNT transposase (IS4 family) protein HT750_RS21045 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HT750_RS21050 ENOG4105C34 Pseudouridine synthase HT750_RS21055 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HT750_RS21060 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HT750_RS21085 ENOG4105CSH Transporter HT750_RS21090 ENOG4105T42 (LipO)protein HT750_RS21095 ENOG4105JIM Phosphatidylserine synthase HT750_RS21100 ENOG4105CD5 CoA-binding domain protein HT750_RS21105 ENOG4106IUH DTW domain containing protein HT750_RS21110 ENOG4105K63 Thioredoxin HT750_RS21115 ENOG4105EIB trna rrna methyltransferase HT750_RS21135 ENOG41090KR LysR family transcriptional Regulator HT750_RS21140 ENOG4105C1J atp-dependent rna helicase HT750_RS21150 ENOG4108IYU L-aspartate oxidase HT750_RS21160 ENOG4105EMN RNA polymerase sigma factor HT750_RS21165 ENOG41069PW sigma-e factor negative regulatory protein HT750_RS21170 ENOG4105VQK sigma E regulatory protein, MucB RseB HT750_RS21175 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HT750_RS21185 ENOG4105C3F Signal peptidase i HT750_RS21205 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HT750_RS21220 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HT750_RS21225 ENOG4106G6Q Transcriptional regulator HT750_RS21230 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HT750_RS21235 ENOG4108Z6B deaminase HT750_RS21245 ENOG4108ETH Formylglycinamide ribotide synthetase HT750_RS21250 ENOG4107WP9 Histidine kinase HT750_RS21255 ENOG4108SKK alpha helix protein HT750_RS21260 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HT750_RS21270 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HT750_RS21280 ENOG4108NZE NAGC-like transcriptional regulator HT750_RS21285 ENOG4107HQ7 repeat protein HT750_RS21290 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HT750_RS21295 ENOG4108F37 ATP-binding component of a transport system HT750_RS21300 ENOG4105CNN ABC, transporter HT750_RS21305 ENOG4105CPQ Dehydrogenase HT750_RS21310 ENOG4108ZKT aldose 1-epimerase HT750_RS21315 ENOG4108SB3 DoxX Family HT750_RS21340 ENOG4105FUY alpha subunit HT750_RS21345 ENOG4108W5M transcriptional regulator HT750_RS21350 ENOG4105D8G Major Facilitator superfamily HT750_RS21355 ENOG4108MN2 Stationary phase inducible protein CsiE HT750_RS21360 ENOG4107XM9 (LipO)protein HT750_RS21365 ENOG4105ECY inositol monophosphatase HT750_RS21385 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HT750_RS21405 ENOG4108ZIT Ferredoxin, 2FE-2S HT750_RS21410 ENOG4105WVQ Fe-S assembly protein IscX HT750_RS21420 ENOG4105YYA enhanced serine sensitivity protein SseB HT750_RS21425 ENOG4105KHC sulfurtransferase HT750_RS21430 ENOG4105DN3 alpha-2-macroglobulin domain protein HT750_RS21435 ENOG4108JQB penicillin-binding protein 1C HT750_RS21465 ENOG4105N21 Membrane HT750_RS21480 ENOG4105VPD cellular component movement HT750_RS21505 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HT750_RS21510 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) HT750_RS21515 ENOG41066DY Membrane HT750_RS21520 ENOG4108ZMA Outer membrane lipoprotein HT750_RS21525 ENOG41062G3 Protein of unknown function (DUF2633) HT750_RS21535 ENOG4105BZU Histidine kinase HT750_RS21540 ENOG4105C9X ppx gppa phosphatase HT750_RS21545 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HT750_RS21550 ENOG4108V3E phosphoribosylglycinamide formyltransferase HT750_RS21555 ENOG4105CXB phosphoribosylaminoimidazole synthetase HT750_RS21565 ENOG4105C2W permease HT750_RS21570 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HT750_RS21575 ENOG4105K89 arsenate reductase HT750_RS21580 ENOG4105ERG peptidase m48, ste24p HT750_RS21585 ENOG4105C02 permease HT750_RS21590 ENOG4105TMB Formate nitrite transporter HT750_RS21595 ENOG4108JUA Transcriptional regulator HT750_RS21600 ENOG4105I6X formate hydrogenlyase maturation HT750_RS21605 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HT750_RS21615 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HT750_RS21620 ENOG4108JPZ Monovalent cation H antiporter subunit D HT750_RS21625 ENOG4107WQX hydrogenase 4 membrane subunit HT750_RS21630 ENOG4105D65 subunit l HT750_RS21635 ENOG4107TDF Formate hydrogenlyase subunit 4 HT750_RS21640 ENOG4108JPZ Monovalent cation H antiporter subunit D HT750_RS21645 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HT750_RS21650 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HT750_RS21655 ENOG4105RH4 Glycine cleavage system transcriptional repressor HT750_RS21665 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HT750_RS21675 ENOG4105CGZ zinc metallopeptidase HT750_RS21685 ENOG4106KED esterase YpfH HT750_RS21700 ENOG4105KUZ arsenate reductase HT750_RS21710 ENOG4105BZS acriflavin resistance protein HT750_RS21715 ENOG4105BZU Histidine kinase HT750_RS21720 ENOG4105BZ8 glutamate synthase HT750_RS21730 ENOG4108PVD exported protein HT750_RS21735 ENOG4105CV1 Transketolase (EC 2.2.1.1) HT750_RS21740 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HT750_RS21745 ENOG4105C6K Malic enzyme HT750_RS21750 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HT750_RS21755 ENOG4106S4J ethanolamine utilization protein EutP HT750_RS21760 ENOG4105NDK ethanolamine utilization protein HT750_RS21765 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HT750_RS21770 ENOG4107WUY phosphate acetyltransferase HT750_RS21775 ENOG4105KNY Microcompartments protein HT750_RS21780 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HT750_RS21785 ENOG4108EKI Dehydrogenase HT750_RS21790 ENOG4107RWI ethanolamine utilization protein eutJ HT750_RS21795 ENOG4105C0A alcohol dehydrogenase HT750_RS21800 ENOG4105ENY Ethanolamine utilization protein eutH HT750_RS21805 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HT750_RS21810 ENOG4105CPD ethanolamine ammonia-lyase HT750_RS21820 ENOG4106D67 ethanolamine utilization protein HT750_RS21825 ENOG4108X49 Ethanolamine utilization protein EutK HT750_RS21830 ENOG4108K3Z AraC family transcriptional regulator HT750_RS21840 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HT750_RS21850 ENOG4105QZU Inner membrane protein YfeZ HT750_RS21855 ENOG4105E7K (LipO)protein HT750_RS21860 ENOG4105EZR dyp-type peroxidase family protein HT750_RS21865 ENOG4107S1E Beta-lactamase HT750_RS21870 ENOG4105C5Y PTS System HT750_RS21885 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HT750_RS21890 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HT750_RS21895 ENOG4108I5D sulfate abc transporter HT750_RS21900 ENOG4105ECW sulfate abc transporter HT750_RS21905 ENOG4108IJ6 ABC transporter HT750_RS21910 ENOG4105C6T cysteine synthase HT750_RS21915 ENOG4105M0Y HT750_RS21925 ENOG4105C5Y PTS System HT750_RS21930 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HT750_RS21940 ENOG4105C6T cysteine synthase HT750_RS21960 ENOG4105VRT cytoplasmic protein HT750_RS21965 ENOG4105DHU Bile acid HT750_RS21970 ENOG4108M0I Transcriptional regulator HT750_RS21975 ENOG4108NFH Sugar hydrolase HT750_RS21980 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HT750_RS21985 ENOG4105EAA nucleoside HT750_RS21995 ENOG4105CN8 Transcriptional regulator HT750_RS22035 ENOG4105GXM Putative transcription regulator (DUF1323) HT750_RS22040 ENOG4105HZG regulatoR HT750_RS22055 ENOG4108KMM Diguanylate cyclase HT750_RS22060 ENOG4105D9N nucleoside HT750_RS22070 ENOG4109076 Conserved Protein HT750_RS22085 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HT750_RS22090 ENOG410863U PTS System HT750_RS22095 ENOG4105DC7 peptidase M24 HT750_RS22100 ENOG4105CN9 Peptidase m42 family protein HT750_RS22105 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HT750_RS22110 ENOG4108CIP transcriptional regulator HT750_RS22115 ENOG4105DY9 regulatoR HT750_RS22120 ENOG4108HRK Histidine kinase HT750_RS22125 ENOG4105CHM Aminotransferase HT750_RS22135 ENOG4105D1S lipid A biosynthesis HT750_RS22140 ENOG4105W9M Membrane HT750_RS22150 ENOG4108V08 YfdX protein HT750_RS22160 ENOG4105CFN oxalyl-CoA decarboxylase HT750_RS22165 ENOG4108N2Y auxin Efflux HT750_RS22170 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HT750_RS22175 ENOG4105BZU Histidine kinase HT750_RS22180 ENOG4108WQH regulatoR HT750_RS22185 ENOG4105CW7 secretion protein, HlyD family HT750_RS22190 ENOG4105C0R drug resistance transporter emrb qaca subfamily HT750_RS22205 ENOG4105W8I Transcriptional regulator HT750_RS22210 ENOG4108W9T type 1 fimbriae regulatory protein HT750_RS22215 ENOG4108W9T type 1 fimbriae regulatory protein HT750_RS22270 ENOG41077V0 CPS-53 (KpLE1) prophage HT750_RS22360 ENOG4105NY2 NinB protein HT750_RS22400 ENOG4105KUS lysozyme HT750_RS22405 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HT750_RS22425 ENOG4108TFU terminase (Small subunit) HT750_RS22430 ENOG4108N0N Phage Terminase Large Subunit HT750_RS22525 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) HT750_RS22565 ENOG4105PTU response to oxidative stress HT750_RS22570 ENOG4105DFP Integrase HT750_RS22580 ENOG4105S64 Formate nitrite transporter HT750_RS22585 ENOG410903C (LipO)protein HT750_RS22595 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HT750_RS22600 ENOG4105KZW UPF0381 protein HT750_RS22615 ENOG4108BY2 phosphohistidine phosphatase HT750_RS22625 ENOG4106PG1 outer membrane usher protein HT750_RS22630 ENOG4108FZ9 Chaperone HT750_RS22635 ENOG4105NEV Fimbrial HT750_RS22640 ENOG4105UGQ Fimbrial HT750_RS22645 ENOG4105US4 fimbrial-like protein yfcP HT750_RS22670 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) HT750_RS22675 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase HT750_RS22685 ENOG4105EJ9 Membrane HT750_RS22690 ENOG4108BPE -transporting atpase HT750_RS22695 ENOG4105MH2 YfcL protein HT750_RS22705 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HT750_RS22710 ENOG4105F9N Major Facilitator Superfamily HT750_RS22715 ENOG4106WZ1 flagella biosynthesis regulator HT750_RS22725 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HT750_RS22735 ENOG4105DQR SNARE associated Golgi HT750_RS22745 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HT750_RS22750 ENOG4108S3P Sporulation domain protein HT750_RS22755 ENOG4105E96 Colicin v production protein HT750_RS22760 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HT750_RS22765 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HT750_RS22770 ENOG4105E89 ABC transporter HT750_RS22775 ENOG4105E89 ABC transporter HT750_RS22780 ENOG4105DSP amino acid AbC transporter HT750_RS22785 ENOG4106YG3 ABC transporter HT750_RS22790 ENOG4108JEH abc transporter atp-binding protein HT750_RS22795 ENOG4105DNE Transposase HT750_RS22805 ENOG4105DFD Na H antiporter HT750_RS22810 ENOG4105ECP epimerase HT750_RS22815 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HT750_RS22820 ENOG4105CYM Glutathione S-transferase HT750_RS22825 ENOG4108SHQ Glutathione S-transferase HT750_RS22830 ENOG4108RE9 Phosphodiesterase HT750_RS22835 ENOG4105PTV Nudix Hydrolase HT750_RS22840 ENOG4105CSX c4-dicarboxylate anaerobic carrier HT750_RS22845 ENOG4105C6K Malic enzyme HT750_RS22850 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HT750_RS22860 ENOG4105XWI UPF0304 protein HT750_RS22865 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HT750_RS22870 ENOG4107QWE )-transporter HT750_RS22880 ENOG4105CHM Aminotransferase HT750_RS22885 ENOG4107NQ8 LysR family Transcriptional regulator HT750_RS22905 ENOG4105GKE subunit e HT750_RS22910 ENOG4107QIZ NADH dehydrogenase HT750_RS22915 ENOG4108IEH NADH dehydrogenase subunit g HT750_RS22930 ENOG4107UFS subunit j HT750_RS22940 ENOG4105D65 subunit l HT750_RS22945 ENOG4105C8S subunit m HT750_RS22955 ENOG4105GDX Domain of unknown function (DUF1877) HT750_RS22975 ENOG4107YB6 acetyltransferase, (GNAT) family HT750_RS22980 ENOG4105TNS Conserved Protein HT750_RS22985 ENOG4105E4F Isochorismate synthase HT750_RS23000 ENOG4108IPT Naphthoate synthase HT750_RS23010 ENOG4105CEY Amp-dependent synthetase and ligase HT750_RS23015 ENOG4106GZG polymyxin resistance protein B HT750_RS23065 ENOG4108UII YfaZ family HT750_RS23075 ENOG4107258 Transcriptional regulator HT750_RS23085 ENOG4105CSP Major Facilitator Superfamily HT750_RS23100 ENOG4105DNE Transposase HT750_RS23105 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HT750_RS23115 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HT750_RS23120 ENOG4105CXY transporter HT750_RS23125 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HT750_RS23130 ENOG4105GZI Transcriptional regulator HT750_RS23135 ENOG4105CZM Major Facilitator HT750_RS23140 ENOG4105FQR PH-inducible protein involved in stress response HT750_RS23145 ENOG4105XPH Ferredoxin HT750_RS23150 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HT750_RS23155 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HT750_RS23160 ENOG4107GHC outer membrane autotransporter HT750_RS23170 ENOG4105DRR Transcriptional regulator, GntR family HT750_RS23180 ENOG4105CXK mandelate racemase muconate lactonizing HT750_RS23185 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HT750_RS23190 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HT750_RS23195 ENOG4108QJJ Protein of unknown function (DUF1175) HT750_RS23200 ENOG4107S52 alpha-2-macroglobulin domain protein HT750_RS23205 ENOG41081SK signal peptide protein HT750_RS23210 ENOG4105EDV vault protein HT750_RS23215 ENOG4105CHU acetyl-coa acetyltransferase HT750_RS23220 ENOG4105CRW Short chain fatty acid transporter HT750_RS23225 ENOG4107QNJ CoA-transferase subunit B HT750_RS23230 ENOG4107QP7 CoA-transferase subunit A HT750_RS23235 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HT750_RS23240 ENOG4105BZU Histidine kinase HT750_RS23245 ENOG4105BZU Histidine kinase HT750_RS23250 ENOG41068CG regulatoR HT750_RS23255 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HT750_RS23260 ENOG4105FCK Membrane HT750_RS23265 ENOG4105CJ2 (LipO)protein HT750_RS23270 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HT750_RS23275 ENOG4105CF1 Alkylated DNA repair protein HT750_RS23280 ENOG4105IBP Cyclic peptide transporter HT750_RS23295 ENOG4108ZNS ferredoxin-type protein NapF HT750_RS23300 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HT750_RS23310 ENOG4108BGM Quinol dehydrogenase periplasmic component HT750_RS23315 ENOG4105GXZ Ferredoxin-type protein NapH HT750_RS23320 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HT750_RS23325 ENOG4105CUW cytochrome C-TYPE protein HT750_RS23330 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HT750_RS23335 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HT750_RS23340 ENOG41060IM Heme exporter protein HT750_RS23345 ENOG4105X3C heme exporter protein HT750_RS23355 ENOG4105DA4 cytochrome c-type biogenesis protein HT750_RS23360 ENOG4107QX9 Thiol disulfide interChange protein HT750_RS23365 ENOG4105KWW Biogenesis protein HT750_RS23370 ENOG4105WH1 Two component transcriptional regulator luxr family HT750_RS23375 ENOG4108MGN ATP-binding component of a transport system HT750_RS23385 ENOG4105E68 Sulfatase HT750_RS23405 ENOG4105CFI type iii restriction protein res subunit HT750_RS23410 ENOG4105I08 Pseudouridine synthase HT750_RS23415 ENOG4105C2C drug resistance transporter, Bcr CflA HT750_RS23420 ENOG4105HG6 HT750_RS23425 ENOG4108JQ5 ABC transporter HT750_RS23430 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HT750_RS23435 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HT750_RS23440 ENOG4105E43 Extracellular solute-binding protein, family 5 HT750_RS23445 ENOG4105CXC rtn protein HT750_RS23450 ENOG4107TT5 NLP P60 protein HT750_RS23455 ENOG41076MN Phosphoesterase, PA-phosphatase related HT750_RS23460 ENOG4105CKI cobalamin synthesis protein HT750_RS23465 ENOG4105DEI Mannitol dehydrogenase HT750_RS23475 ENOG4105KRS Proteinase inhibitor HT750_RS23480 ENOG4105S8Q sugar efflux transporter HT750_RS23485 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HT750_RS23490 ENOG4105DE4 1-phosphofructokinase HT750_RS23495 ENOG4105DM4 PTS System HT750_RS23500 ENOG4105DD7 kinase (PfkB family HT750_RS23505 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HT750_RS23510 ENOG4105D9N nucleoside HT750_RS23515 ENOG4108Y4K DNA-binding transcriptional activator HT750_RS23525 ENOG4105D9N nucleoside HT750_RS23530 ENOG4105DD7 kinase (PfkB family HT750_RS23540 ENOG4105HMI Membrane HT750_RS23545 ENOG4105DUM transcriptional regulator, lysR family HT750_RS23550 ENOG4108IQI permease HT750_RS23555 ENOG4105D05 Receptor HT750_RS23560 ENOG4105CXY transporter HT750_RS23565 ENOG4105EAC phosphoserine phosphatase HT750_RS23570 ENOG4105EJQ L-serine dehydratase HT750_RS23580 ENOG4105C4W S-formylglutathione hydrolase HT750_RS23590 ENOG4105DHF Membrane HT750_RS23595 ENOG41060NJ transcriptional regulator HT750_RS23600 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HT750_RS23605 ENOG4105C2J ABC transporter HT750_RS23610 ENOG4108HWV )-transporter HT750_RS23615 ENOG4107SJI Dehydrogenase HT750_RS23620 ENOG4105BZ8 glutamate synthase HT750_RS23625 ENOG4105Y9N Membrane HT750_RS23630 ENOG4107GZ4 SanA protein HT750_RS23640 ENOG41067MG lrgb family HT750_RS23650 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HT750_RS23655 ENOG4105EQR Transposase IS116 IS110 IS902 HT750_RS23660 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HT750_RS23665 ENOG4105CPB ATP-dependent endonuclease of the OLD family HT750_RS23670 ENOG4108MJ5 VirK protein HT750_RS23675 ENOG4105DJY efflux transporter, rnd family, mfp subunit HT750_RS23680 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HT750_RS23685 ENOG4105VEQ Cold shock protein HT750_RS23695 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HT750_RS23705 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HT750_RS23715 ENOG4108JJ8 (ABC) transporter HT750_RS23720 ENOG4108JJ9 ABC, transporter HT750_RS23725 ENOG4105C3M thioredoxin reductase HT750_RS23735 ENOG4105CNU cell division protein FtsK HT750_RS23745 ENOG4105D1H recombination factor protein RarA HT750_RS23755 ENOG4107QY8 reductase HT750_RS23760 ENOG4105QAX Iron-sulfur HT750_RS23765 ENOG4107KGK dmso reductase anchor subunit HT750_RS23770 ENOG4105CHJ isochorismatase hydrolase HT750_RS23780 ENOG4105E5D amino acid HT750_RS23785 ENOG410642W LysR family Transcriptional regulator HT750_RS23790 ENOG4108X0B nad(p)h dehydrogenase (quinone) HT750_RS23795 ENOG4105F1A Pyruvate formate-lyase HT750_RS23800 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)