locus-tag	class	description
LY180_RS00005	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LY180_RS00015	COG0460	homoserine dehydrogenase
LY180_RS00015	COG0527	aspartate kinase activity
LY180_RS00025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LY180_RS00040	COG3547	Transposase (IS116 IS110 IS902 family)
LY180_RS00050	COG1115	amino acid carrier protein
LY180_RS00060	COG0521	Mo-molybdopterin cofactor biosynthetic process
LY180_RS00065	COG1584	GPR1 FUN34 yaaH family protein
LY180_RS00070	COG4735	regulation of single-species biofilm formation
LY180_RS00100	COG0583	DNA-binding transcription factor activity
LY180_RS00110	COG3188	usher protein
LY180_RS00130	COG0196	riboflavin kinase activity
LY180_RS00145	COG1047	Peptidyl-prolyl cis-trans
LY180_RS00175	COG0505	Belongs to the CarA family
LY180_RS00180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LY180_RS00235	COG0644	oxidoreductase
LY180_RS00240	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LY180_RS00245	COG2271	Major facilitator Superfamily
LY180_RS00260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LY180_RS00285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LY180_RS00290	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LY180_RS00295	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LY180_RS00300	COG0564	pseudouridine synthase activity
LY180_RS00310	COG0417	DNA replication proofreading
LY180_RS00315	COG0235	Class ii aldolase
LY180_RS00330	COG4977	sequence-specific DNA binding
LY180_RS00335	COG0586	Pfam SNARE associated Golgi protein
LY180_RS00345	COG1178	ABC-type Fe3 transport system permease component
LY180_RS00350	COG4143	(ABC) transporter
LY180_RS00365	COG2814	Major facilitator Superfamily
LY180_RS00380	COG0473	3-isopropylmalate dehydrogenase activity
LY180_RS00395	COG0583	DNA-binding transcription factor activity
LY180_RS00400	COG0028	Belongs to the TPP enzyme family
LY180_RS00405	COG0440	acetolactate synthase activity
LY180_RS00415	COG1609	Transcriptional regulator
LY180_RS00430	COG3116	cell division
LY180_RS00435	COG0768	penicillin binding
LY180_RS00440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LY180_RS00445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LY180_RS00460	COG0772	Belongs to the SEDS family
LY180_RS00475	COG1181	Belongs to the D-alanine--D-alanine ligase family
LY180_RS00480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LY180_RS00485	COG0849	cell division
LY180_RS00490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LY180_RS00510	COG0494	nUDIX hydrolase
LY180_RS00530	COG0237	dephospho-CoA kinase activity
LY180_RS00540	COG1459	type II secretion system
LY180_RS00545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LY180_RS00550	COG4969	Belongs to the N-Me-Phe pilin family
LY180_RS00560	COG0157	Belongs to the NadC ModD family
LY180_RS00565	COG3023	N-Acetylmuramoyl-L-alanine amidase
LY180_RS00570	COG3725	Membrane protein required for beta-lactamase induction
LY180_RS00575	COG1113	amino acid transport
LY180_RS00580	COG2186	Transcriptional regulator
LY180_RS00585	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LY180_RS00590	COG0508	dehydrogenase complex catalyzes the overall conversion of
LY180_RS00595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LY180_RS00600	COG3064	Membrane
LY180_RS00605	COG1049	propionate catabolic process, 2-methylcitrate cycle
LY180_RS00630	COG2132	Multicopper oxidase
LY180_RS00635	COG4993	Dehydrogenase
LY180_RS00640	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LY180_RS00645	COG0288	reversible hydration of carbon dioxide
LY180_RS00650	COG1131	(ABC) transporter
LY180_RS00655	COG0842	Transport permease protein
LY180_RS00660	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS00665	COG0726	polysaccharide deacetylase
LY180_RS00675	COG5464	transposase or invertase
LY180_RS00690	COG3539	Fimbrial protein
LY180_RS00695	COG3539	Fimbrial protein
LY180_RS00700	COG3539	Fimbrial protein
LY180_RS00705	COG3539	Fimbrial protein
LY180_RS00710	COG3188	usher protein
LY180_RS00715	COG3121	Chaperone
LY180_RS00720	COG3539	Fimbrial protein
LY180_RS00725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LY180_RS00730	COG0617	tRNA 3'-terminal CCA addition
LY180_RS00740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LY180_RS00750	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LY180_RS00755	COG1643	Atp-dependent helicase
LY180_RS00765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LY180_RS00770	COG4774	siderophore transport
LY180_RS00775	COG1120	ATPase activity
LY180_RS00780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LY180_RS00785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LY180_RS00805	COG2860	membrane
LY180_RS00810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LY180_RS00825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LY180_RS00830	COG3835	regulator
LY180_RS00850	COG0024	Methionine aminopeptidase
LY180_RS00875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LY180_RS00880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LY180_RS00885	COG0575	Belongs to the CDS family
LY180_RS00890	COG0750	zinc metalloprotease
LY180_RS00900	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LY180_RS00905	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LY180_RS00930	COG0587	DNA-directed DNA polymerase activity
LY180_RS00940	COG1982	Orn Lys Arg decarboxylase major
LY180_RS00945	COG0346	lactoylglutathione lyase activity
LY180_RS00955	COG4568	rho-dependent transcription termination
LY180_RS00965	COG4681	YaeQ
LY180_RS00970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LY180_RS00975	COG3015	lipoprotein NlpE involved in copper resistance
LY180_RS00980	COG0791	NLP P60 protein
LY180_RS00990	COG1720	tRNA m6t6A37 methyltransferase activity
LY180_RS01000	COG1464	Belongs to the NlpA lipoprotein family
LY180_RS01005	COG2011	ABC-type metal ion transport system permease component
LY180_RS01010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LY180_RS01015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LY180_RS01050	COG0656	L-ascorbic acid biosynthetic process
LY180_RS01055	COG0583	DNA-binding transcription factor activity
LY180_RS01065	COG2226	methyltransferase
LY180_RS01070	COG1388	LysM domain
LY180_RS01070	COG0741	lytic transglycosylase activity
LY180_RS01080	COG2226	methyltransferase
LY180_RS01090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LY180_RS01110	COG4104	PAAR repeat-containing protein
LY180_RS01115	COG3157	Type VI secretion system effector, Hcp
LY180_RS01215	COG3209	COG3209 Rhs family protein
LY180_RS01225	COG5433	transposase activity
LY180_RS01230	COG5433	transposase activity
LY180_RS01235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LY180_RS01245	COG1960	acyl-CoA dehydrogenase activity
LY180_RS01255	COG0121	glutamine amidotransferase
LY180_RS01260	COG3034	peptidoglycan biosynthetic process
LY180_RS01265	COG3041	Addiction module toxin RelE StbE family
LY180_RS01270	COG3077	Addiction module antitoxin, RelB DinJ family
LY180_RS01275	COG0791	NLP P60 protein
LY180_RS01305	COG1987	bacterial-type flagellum assembly
LY180_RS01330	COG1677	Flagellar hook-basal body complex protein FliE
LY180_RS01340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LY180_RS01360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LY180_RS01375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LY180_RS01380	COG5301	cellulose 1,4-beta-cellobiosidase activity
LY180_RS01405	COG3299	homolog of phage Mu protein gp47
LY180_RS01410	COG4381	Mu-like prophage protein gp46
LY180_RS01415	COG4384	Bacteriophage Mu Gp45 protein
LY180_RS01425	COG4228	DNA circulation
LY180_RS01435	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
LY180_RS01445	COG4386	tail sheath protein
LY180_RS01470	COG4397	Mu-like prophage major head subunit gpT
LY180_RS01475	COG4388	Caudovirus prohead serine protease
LY180_RS01480	COG5005	Phage virion morphogenesis
LY180_RS01485	COG2369	cell adhesion
LY180_RS01490	COG4383	Mu-like prophage protein gp29
LY180_RS01495	COG4373	Mu-like prophage FluMu protein gp28
LY180_RS01505	COG0640	Transcriptional regulator
LY180_RS01535	COG5566	PFAM Mor transcription activator
LY180_RS01580	COG4396	Host-nuclease inhibitor protein Gam
LY180_RS01610	COG2842	Transposition protein
LY180_RS01615	COG2801	Transposase and inactivated derivatives
LY180_RS01620	COG3423	Transcriptional regulator
LY180_RS01655	COG1815	bacterial-type flagellum-dependent cell motility
LY180_RS01660	COG1558	bacterial-type flagellum-dependent cell motility
LY180_RS01670	COG1749	Flagellar hook protein flgE
LY180_RS01675	COG4787	bacterial-type flagellum-dependent cell motility
LY180_RS01680	COG4786	Flagellar basal body rod
LY180_RS01705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LY180_RS01725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LY180_RS01730	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LY180_RS01755	COG1191	sigma factor activity
LY180_RS01760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LY180_RS01775	COG0454	-acetyltransferase
LY180_RS01780	COG1690	Belongs to the RtcB family
LY180_RS01785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LY180_RS01790	COG2195	Cleaves the N-terminal amino acid of tripeptides
LY180_RS01810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LY180_RS01830	COG0583	DNA-binding transcription factor activity
LY180_RS01835	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LY180_RS01840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LY180_RS01845	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LY180_RS01850	COG2080	2 iron, 2 sulfur cluster binding
LY180_RS01865	COG0727	PFAM Uncharacterised protein family (UPF0153)
LY180_RS01870	COG3121	Chaperone
LY180_RS01880	COG3188	usher protein
LY180_RS01920	COG1388	LysM domain
LY180_RS01925	COG2207	Transcriptional regulator
LY180_RS01925	COG3708	Transcriptional regulator
LY180_RS01930	COG0656	L-ascorbic acid biosynthetic process
LY180_RS01935	COG3059	membrane
LY180_RS01945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LY180_RS01950	COG2207	Transcriptional regulator
LY180_RS01955	COG0247	lactate metabolic process
LY180_RS01960	COG1139	Iron-sulfur cluster binding protein
LY180_RS01965	COG1556	Lactate utilization protein
LY180_RS01995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LY180_RS02005	COG2771	luxR family
LY180_RS02005	COG2200	EAL domain
LY180_RS02010	COG0583	DNA-binding transcription factor activity
LY180_RS02020	COG0666	response to abiotic stimulus
LY180_RS02030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LY180_RS02035	COG1304	FMN binding
LY180_RS02040	COG0549	Belongs to the carbamate kinase family
LY180_RS02045	COG0402	S-adenosylhomocysteine deaminase activity
LY180_RS02055	COG1879	ABC-type sugar transport system periplasmic component
LY180_RS02060	COG1129	ABC transporter
LY180_RS02065	COG1172	Belongs to the binding-protein-dependent transport system permease family
LY180_RS02075	COG1064	alcohol dehydrogenase
LY180_RS02090	COG1280	lysine exporter protein (LysE YggA)
LY180_RS02100	COG3829	transcription factor binding
LY180_RS02105	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LY180_RS02110	COG0372	Belongs to the citrate synthase family
LY180_RS02115	COG2079	MmgE PrpD family protein
LY180_RS02120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LY180_RS02125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LY180_RS02130	COG0402	S-adenosylhomocysteine deaminase activity
LY180_RS02135	COG0583	DNA-binding transcription factor activity
LY180_RS02140	COG0288	reversible hydration of carbon dioxide
LY180_RS02150	COG2807	transmembrane transport
LY180_RS02155	COG0110	maltose O-acetyltransferase activity
LY180_RS02160	COG2223	nitrite transmembrane transporter activity
LY180_RS02170	COG1609	Transcriptional regulator
LY180_RS02175	COG1414	Transcriptional regulator
LY180_RS02210	COG2814	Major facilitator Superfamily
LY180_RS02215	COG3122	Protein conserved in bacteria
LY180_RS02245	COG1215	transferase activity, transferring glycosyl groups
LY180_RS02255	COG1215	transferase activity, transferring glycosyl groups
LY180_RS02260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LY180_RS02265	COG4521	taurine ABC transporter
LY180_RS02275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LY180_RS02280	COG2175	clavaminate synthase activity
LY180_RS02285	COG0113	porphobilinogen synthase activity
LY180_RS02295	COG1785	Belongs to the alkaline phosphatase family
LY180_RS02305	COG3706	GGDEF domain
LY180_RS02310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LY180_RS02335	COG4126	flavin adenine dinucleotide binding
LY180_RS02355	COG1940	carbohydrate kinase activity
LY180_RS02360	COG2814	Major facilitator Superfamily
LY180_RS02365	COG0419	ATPase involved in DNA repair
LY180_RS02370	COG0420	3'-5' exonuclease activity
LY180_RS02375	COG0745	RESPONSE REGULATOR receiver
LY180_RS02380	COG5002	protein histidine kinase activity
LY180_RS02385	COG1114	Component of the transport system for branched-chain amino acids
LY180_RS02390	COG1113	amino acid transport
LY180_RS02395	COG0366	Alpha amylase catalytic
LY180_RS02415	COG1862	Preprotein translocase
LY180_RS02420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LY180_RS02425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LY180_RS02430	COG1403	HNH endonuclease
LY180_RS02440	COG3248	Nucleoside-binding outer membrane protein
LY180_RS02445	COG4238	major outer membrane lipoprotein
LY180_RS02455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LY180_RS02455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LY180_RS02470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LY180_RS02475	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LY180_RS02480	COG0667	Aldo Keto reductase
LY180_RS02490	COG0142	geranyltranstransferase activity
LY180_RS02505	COG0693	protein deglycase activity
LY180_RS02510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LY180_RS02520	COG2814	Major facilitator Superfamily
LY180_RS02545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LY180_RS02550	COG1845	cytochrome c oxidase, subunit III
LY180_RS02555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LY180_RS02560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LY180_RS02565	COG2223	nitrite transmembrane transporter activity
LY180_RS02570	COG3056	Lipoprotein
LY180_RS02575	COG0271	Belongs to the BolA IbaG family
LY180_RS02600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LY180_RS02605	COG0776	regulation of translation
LY180_RS02610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LY180_RS02615	COG1555	photosystem II stabilization
LY180_RS02620	COG0824	Thioesterase
LY180_RS02630	COG4533	DNA binding
LY180_RS02640	COG1522	sequence-specific DNA binding
LY180_RS02645	COG1132	(ABC) transporter
LY180_RS02650	COG1132	(ABC) transporter
LY180_RS02655	COG0347	Belongs to the P(II) protein family
LY180_RS02660	COG0004	ammonium transporteR
LY180_RS02665	COG1946	Acyl-CoA thioesterase
LY180_RS02670	COG3126	Type III secretion system lipoprotein chaperone (YscW)
LY180_RS02675	COG3695	enzyme binding
LY180_RS02680	COG5507	3-demethylubiquinone-9 3-methyltransferase
LY180_RS02695	COG0110	maltose O-acetyltransferase activity
LY180_RS02710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LY180_RS02715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LY180_RS02720	COG1309	transcriptional regulator
LY180_RS02725	COG1196	nuclear chromosome segregation
LY180_RS02725	COG3264	Mechanosensitive ion channel
LY180_RS02740	COG3923	Primosomal replication protein n
LY180_RS02745	COG2832	Protein of unknown function (DUF454)
LY180_RS02755	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LY180_RS02790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LY180_RS02795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LY180_RS02795	COG4651	solute:proton antiporter activity
LY180_RS02800	COG2223	nitrite transmembrane transporter activity
LY180_RS02805	COG0737	Belongs to the 5'-nucleotidase family
LY180_RS02810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LY180_RS02815	COG3735	TraB family
LY180_RS02820	COG3093	addiction module antidote protein HigA
LY180_RS02825	COG2217	Heavy metal translocating P-type atpase
LY180_RS02830	COG2066	Belongs to the glutaminase family
LY180_RS02835	COG0531	amino acid
LY180_RS02840	COG0789	Transcriptional regulator
LY180_RS02845	COG1585	Membrane protein implicated in regulation of membrane protease activity
LY180_RS02850	COG0330	HflC and HflK could
LY180_RS02855	COG4619	ABC transporter
LY180_RS02860	COG0390	transport system, permease component
LY180_RS02865	COG3118	belongs to the thioredoxin family
LY180_RS02870	COG0300	oxidoreductase activity
LY180_RS02875	COG2755	lipolytic protein G-D-S-L family
LY180_RS02880	COG4181	ATPase activity
LY180_RS02885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LY180_RS02890	COG3209	COG3209 Rhs family protein
LY180_RS02900	COG3209	COG3209 Rhs family protein
LY180_RS02910	COG2801	Transposase and inactivated derivatives
LY180_RS02920	COG0583	DNA-binding transcription factor activity
LY180_RS02930	COG1414	Transcriptional regulator
LY180_RS02935	COG3960	tartronate-semialdehyde synthase activity
LY180_RS02940	COG3622	Belongs to the hyi family
LY180_RS02945	COG2084	Dehydrogenase
LY180_RS02950	COG1953	Uracil, thiamine, allantoin
LY180_RS02960	COG2233	PERMEase
LY180_RS02965	COG1929	Belongs to the glycerate kinase type-1 family
LY180_RS02970	COG3257	ureidoglycine aminohydrolase activity
LY180_RS02975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LY180_RS02980	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LY180_RS02985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LY180_RS02990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LY180_RS03000	COG0549	Belongs to the carbamate kinase family
LY180_RS03005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LY180_RS03010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LY180_RS03020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LY180_RS03030	COG1988	membrane-bound metal-dependent
LY180_RS03035	COG2501	S4 domain
LY180_RS03045	COG3539	Fimbrial protein
LY180_RS03050	COG3121	Chaperone
LY180_RS03055	COG3188	usher protein
LY180_RS03060	COG3539	Fimbrial protein
LY180_RS03065	COG3539	Fimbrial protein
LY180_RS03070	COG2197	response regulator
LY180_RS03080	COG2207	Transcriptional regulator
LY180_RS03090	COG4783	chaperone-mediated protein folding
LY180_RS03095	COG1215	transferase activity, transferring glycosyl groups
LY180_RS03100	COG5433	transposase activity
LY180_RS03115	COG4104	PAAR repeat-containing protein
LY180_RS03115	COG3209	COG3209 Rhs family protein
LY180_RS03125	COG4104	PAAR repeat-containing protein
LY180_RS03125	COG3209	COG3209 Rhs family protein
LY180_RS03135	COG4104	PAAR repeat-containing protein
LY180_RS03135	COG3209	COG3209 Rhs family protein
LY180_RS03150	COG5002	protein histidine kinase activity
LY180_RS03155	COG0745	RESPONSE REGULATOR receiver
LY180_RS03160	COG1538	Outer membrane efflux protein
LY180_RS03165	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LY180_RS03170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LY180_RS03175	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LY180_RS03180	COG1113	amino acid transport
LY180_RS03185	COG0668	transmembrane transport
LY180_RS03190	COG0778	Nitroreductase
LY180_RS03195	COG2315	Protein conserved in bacteria
LY180_RS03230	COG2977	Belongs to the P-Pant transferase superfamily
LY180_RS03235	COG4771	TonB-dependent receptor
LY180_RS03240	COG2382	esterase
LY180_RS03245	COG3251	PFAM MbtH domain protein
LY180_RS03250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LY180_RS03250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LY180_RS03255	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LY180_RS03260	COG1120	ATPase activity
LY180_RS03265	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LY180_RS03270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LY180_RS03280	COG4592	Periplasmic binding protein
LY180_RS03285	COG1169	isochorismate synthase
LY180_RS03290	COG1021	2,3-dihydroxybenzoate-AMP ligase
LY180_RS03295	COG3433	isochorismatase activity
LY180_RS03295	COG1535	isochorismatase
LY180_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS03305	COG2050	protein possibly involved in aromatic compounds catabolism
LY180_RS03310	COG1966	Carbon starvation protein
LY180_RS03315	COG2879	small protein
LY180_RS03320	COG0371	Dehydrogenase
LY180_RS03325	COG0436	Aminotransferase
LY180_RS03330	COG1475	DNA binding
LY180_RS03335	COG3969	phosphoadenosine phosphosulfate
LY180_RS03340	COG0583	DNA-binding transcription factor activity
LY180_RS03345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LY180_RS03350	COG0450	alkyl hydroperoxide reductase
LY180_RS03355	COG3634	alkyl hydroperoxide reductase activity
LY180_RS03360	COG0589	response to stress
LY180_RS03365	COG1063	alcohol dehydrogenase
LY180_RS03375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LY180_RS03380	COG3719	Belongs to the RNase T2 family
LY180_RS03385	COG0471	metal ion transport
LY180_RS03400	COG3051	citrate lyase alpha subunit
LY180_RS03405	COG2301	Belongs to the HpcH HpaI aldolase family
LY180_RS03415	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LY180_RS03420	COG3290	protein histidine kinase activity
LY180_RS03425	COG4565	transcriptional regulatory protein
LY180_RS03430	COG3069	C4-dicarboxylate transmembrane transporter activity
LY180_RS03450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LY180_RS03455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LY180_RS03465	COG0583	DNA-binding transcription factor activity
LY180_RS03485	COG1686	Belongs to the peptidase S11 family
LY180_RS03490	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LY180_RS03495	COG0772	Belongs to the SEDS family
LY180_RS03500	COG0768	penicillin binding
LY180_RS03510	COG0799	negative regulation of ribosome biogenesis
LY180_RS03515	COG0406	alpha-ribazole phosphatase activity
LY180_RS03525	COG1466	dna polymerase III delta subunit
LY180_RS03540	COG2888	peptidyl-tyrosine sulfation
LY180_RS03545	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LY180_RS03555	COG2214	Heat shock protein DnaJ domain protein
LY180_RS03560	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LY180_RS03570	COG2214	Heat shock protein DnaJ domain protein
LY180_RS03575	COG0443	Heat shock 70 kDa protein
LY180_RS03585	COG1126	abc transporter atp-binding protein
LY180_RS03590	COG0765	amino acid transport
LY180_RS03595	COG0765	amino acid transport
LY180_RS03600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LY180_RS03610	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LY180_RS03615	COG4535	Mg2 and Co2 transporter CorC
LY180_RS03625	COG1702	phosphate starvation-inducible protein PhoH
LY180_RS03635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LY180_RS03670	COG0367	asparagine synthase
LY180_RS03675	COG0647	UMP catabolic process
LY180_RS03680	COG1940	carbohydrate kinase activity
LY180_RS03680	COG1846	Transcriptional regulator
LY180_RS03685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LY180_RS03695	COG1263	PTS System
LY180_RS03695	COG2190	(PTS) system
LY180_RS03695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS03715	COG0735	belongs to the Fur family
LY180_RS03730	COG0716	FMN binding
LY180_RS03740	COG0596	Alpha beta hydrolase
LY180_RS03745	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LY180_RS03750	COG0033	Phosphoglucomutase
LY180_RS03755	COG0531	amino acid
LY180_RS03760	COG1982	Orn Lys Arg decarboxylase major
LY180_RS03770	COG0745	RESPONSE REGULATOR receiver
LY180_RS03775	COG2205	protein histidine kinase activity
LY180_RS03805	COG3209	COG3209 Rhs family protein
LY180_RS03815	COG5433	transposase activity
LY180_RS03825	COG3272	Protein of unknown function (DUF1722)
LY180_RS03830	COG0415	Belongs to the DNA photolyase family
LY180_RS03840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LY180_RS03845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LY180_RS03850	COG1984	allophanate hydrolase subunit 2
LY180_RS03860	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LY180_RS03865	COG3180	Ammonia monooxygenase
LY180_RS03870	COG3539	Fimbrial protein
LY180_RS03875	COG3121	Chaperone
LY180_RS03880	COG3188	usher protein
LY180_RS03885	COG3539	Fimbrial protein
LY180_RS03890	COG0372	Belongs to the citrate synthase family
LY180_RS03900	COG2009	succinate dehydrogenase
LY180_RS03905	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LY180_RS03910	COG1053	succinate dehydrogenase
LY180_RS03915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LY180_RS03925	COG0567	Dehydrogenase, E1 component
LY180_RS03930	COG0508	dehydrogenase complex catalyzes the overall conversion of
LY180_RS03940	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LY180_RS03945	COG2188	Transcriptional regulator
LY180_RS03950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS03950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS03950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS03955	COG0383	alpha-mannosidase activity
LY180_RS03965	COG1271	oxidase subunit
LY180_RS03970	COG1294	oxidase, subunit
LY180_RS03975	COG4890	Cyd operon protein YbgT
LY180_RS03980	COG3790	cyd operon protein YbgE
LY180_RS03985	COG0824	Thioesterase
LY180_RS03990	COG0811	peptide transport
LY180_RS03995	COG0848	biopolymer transport protein
LY180_RS04000	COG3064	Membrane
LY180_RS04010	COG2885	chlorophyll binding
LY180_RS04015	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LY180_RS04060	COG3201	nicotinamide mononucleotide transporter
LY180_RS04065	COG1230	cation diffusion facilitator family transporter
LY180_RS04080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LY180_RS04090	COG2017	converts alpha-aldose to the beta-anomer
LY180_RS04100	COG1085	galactose-1-phosphate uridylyltransferase
LY180_RS04105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LY180_RS04110	COG1119	ATPase activity
LY180_RS04120	COG3585	molybdate ion transport
LY180_RS04120	COG2005	Transcriptional regulator
LY180_RS04130	COG0725	ABC transporter, periplasmic molybdate-binding protein
LY180_RS04135	COG4149	molybdate abc transporter
LY180_RS04145	COG0561	phosphatase activity
LY180_RS04155	COG0583	DNA-binding transcription factor activity
LY180_RS04160	COG2828	Protein conserved in bacteria
LY180_RS04165	COG0471	metal ion transport
LY180_RS04170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LY180_RS04175	COG4677	pectinesterase activity
LY180_RS04180	COG1881	PFAM PEBP family protein
LY180_RS04185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LY180_RS04200	COG2226	methyltransferase
LY180_RS04205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LY180_RS04215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LY180_RS04230	COG0521	Mo-molybdopterin cofactor biosynthetic process
LY180_RS04240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LY180_RS04245	COG0314	molybdopterin synthase activity
LY180_RS04250	COG0670	Belongs to the BI1 family
LY180_RS04255	COG0670	Belongs to the BI1 family
LY180_RS04260	COG0392	lysyltransferase activity
LY180_RS04265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LY180_RS04270	COG3568	Endonuclease Exonuclease Phosphatase
LY180_RS04280	COG0842	Transport permease protein
LY180_RS04285	COG0842	Transport permease protein
LY180_RS04290	COG1131	(ABC) transporter
LY180_RS04300	COG1309	transcriptional regulator
LY180_RS04305	COG0513	Belongs to the DEAD box helicase family
LY180_RS04315	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
LY180_RS04320	COG1199	ATP-dependent helicase activity
LY180_RS04325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LY180_RS04330	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LY180_RS04340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LY180_RS04350	COG4774	siderophore transport
LY180_RS04365	COG0668	transmembrane transport
LY180_RS04375	COG1126	abc transporter atp-binding protein
LY180_RS04380	COG0765	amino acid transport
LY180_RS04385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LY180_RS04400	COG5006	permease, DMT superfamily
LY180_RS04405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LY180_RS04410	COG2194	sulfuric ester hydrolase activity
LY180_RS04420	COG1321	iron dependent repressor
LY180_RS04425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LY180_RS04430	COG1376	ErfK ybiS ycfS ynhG family protein
LY180_RS04435	COG0488	(ABC) transporter
LY180_RS04440	COG3547	Transposase (IS116 IS110 IS902 family)
LY180_RS04450	COG0561	phosphatase activity
LY180_RS04455	COG1882	Formate acetyltransferase
LY180_RS04460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LY180_RS04465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LY180_RS04470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LY180_RS04475	COG0303	'Molybdopterin
LY180_RS04480	COG1446	asparaginase
LY180_RS04505	COG2200	EAL domain
LY180_RS04510	COG2199	diguanylate cyclase activity
LY180_RS04525	COG2133	pyrroloquinoline quinone binding
LY180_RS04530	COG0625	glutathione transferase activity
LY180_RS04535	COG1686	Belongs to the peptidase S11 family
LY180_RS04540	COG1349	DNA-binding transcription factor activity
LY180_RS04545	COG0671	phosphoesterase, PA-phosphatase related
LY180_RS04550	COG2814	Major facilitator Superfamily
LY180_RS04560	COG0561	phosphatase activity
LY180_RS04565	COG0738	Major facilitator superfamily
LY180_RS04570	COG3226	Transcriptional regulator
LY180_RS04585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LY180_RS04595	COG0778	Nitroreductase
LY180_RS04615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LY180_RS04620	COG3842	ATPase activity
LY180_RS04625	COG1176	ABC-type spermidine putrescine transport system, permease component I
LY180_RS04630	COG1177	transmembrane transport
LY180_RS04645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LY180_RS04650	COG4160	amino acid transport
LY180_RS04655	COG4215	(ABC) transporter
LY180_RS04660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LY180_RS04665	COG1126	abc transporter atp-binding protein
LY180_RS04680	COG3023	N-Acetylmuramoyl-L-alanine amidase
LY180_RS04685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LY180_RS04690	COG0702	epimerase
LY180_RS04695	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LY180_RS04700	COG0028	Belongs to the TPP enzyme family
LY180_RS04705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LY180_RS04715	COG2431	L-lysine efflux transmembrane transporter activity
LY180_RS04730	COG3593	DNA synthesis involved in DNA repair
LY180_RS04735	COG2990	Protein conserved in bacteria
LY180_RS04740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LY180_RS04745	COG1136	(ABC) transporter
LY180_RS04745	COG0577	efflux transmembrane transporter activity
LY180_RS04750	COG1278	Cold shock
LY180_RS04760	COG0542	response to heat
LY180_RS04780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LY180_RS04785	COG4988	ABC transporter
LY180_RS04790	COG0492	ferredoxin-NADP+ reductase activity
LY180_RS04795	COG1522	sequence-specific DNA binding
LY180_RS04810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LY180_RS04820	COG0243	molybdopterin cofactor binding
LY180_RS04825	COG0437	4 iron, 4 sulfur cluster binding
LY180_RS04830	COG3302	dmso reductase anchor subunit
LY180_RS04835	COG1335	isochorismatase
LY180_RS04845	COG0531	amino acid
LY180_RS04850	COG0583	DNA-binding transcription factor activity
LY180_RS04855	COG2249	NAD(P)H dehydrogenase (quinone) activity
LY180_RS04860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LY180_RS04865	COG1882	Formate acetyltransferase
LY180_RS04870	COG2116	formate transmembrane transporter activity
LY180_RS04875	COG1944	ATP diphosphatase activity
LY180_RS04880	COG2323	membrane
LY180_RS04895	COG0501	Belongs to the peptidase M48B family
LY180_RS04905	COG0539	negative regulation of cytoplasmic translation
LY180_RS04915	COG2333	competence protein COMEC
LY180_RS04915	COG0658	competence protein
LY180_RS04920	COG1132	(ABC) transporter
LY180_RS04925	COG1663	tetraacyldisaccharide 4'-kinase activity
LY180_RS04930	COG3214	Protein conserved in bacteria
LY180_RS04945	COG3173	Aminoglycoside phosphotransferase
LY180_RS04950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LY180_RS04955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LY180_RS04965	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LY180_RS04975	COG2989	Protein conserved in bacteria
LY180_RS04980	COG3108	Peptidase M15
LY180_RS04985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LY180_RS04990	COG1448	Aminotransferase
LY180_RS05015	COG0308	aminopeptidase N
LY180_RS05025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LY180_RS05035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LY180_RS05040	COG0431	NADPH-dependent FMN reductase
LY180_RS05045	COG3539	Fimbrial protein
LY180_RS05050	COG3121	Chaperone
LY180_RS05055	COG3188	usher protein
LY180_RS05060	COG3539	Fimbrial protein
LY180_RS05065	COG3539	Fimbrial protein
LY180_RS05070	COG3539	Fimbrial protein
LY180_RS05075	COG3121	Chaperone
LY180_RS05090	COG0633	Ferredoxin
LY180_RS05090	COG3217	Mosc domain protein beta barrel domain protein
LY180_RS05100	COG0488	(ABC) transporter
LY180_RS05105	COG2995	paraquat-inducible protein a
LY180_RS05110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LY180_RS05110	COG3008	intermembrane lipid transfer
LY180_RS05115	COG3009	Protein conserved in bacteria
LY180_RS05120	COG3130	regulation of translation
LY180_RS05130	COG1067	ATP-dependent peptidase activity
LY180_RS05140	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LY180_RS05140	COG2885	chlorophyll binding
LY180_RS05155	COG3070	regulator of competence-specific genes
LY180_RS05160	COG1289	transmembrane transporter activity
LY180_RS05165	COG3304	Inner membrane component domain
LY180_RS05170	COG0210	DNA helicase
LY180_RS05190	COG1832	CoA-binding protein
LY180_RS05205	COG1254	Belongs to the acylphosphatase family
LY180_RS05210	COG2920	part of a sulfur-relay system
LY180_RS05215	COG0670	Belongs to the BI1 family
LY180_RS05225	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
LY180_RS05230	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LY180_RS05235	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
LY180_RS05240	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LY180_RS05245	COG1999	signal sequence binding
LY180_RS05250	COG1773	rubredoxin
LY180_RS05255	COG1271	oxidase subunit
LY180_RS05260	COG1294	oxidase, subunit
LY180_RS05275	COG0489	protein tyrosine kinase activity
LY180_RS05275	COG3206	protein involved in exopolysaccharide biosynthesis
LY180_RS05280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LY180_RS05285	COG1596	polysaccharide export
LY180_RS05290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LY180_RS05310	COG1278	Cold shock
LY180_RS05315	COG1278	Cold shock
LY180_RS05330	COG0348	domain, Protein
LY180_RS05335	COG2205	protein histidine kinase activity
LY180_RS05335	COG2198	Histidine kinase
LY180_RS05335	COG0784	Response regulator, receiver
LY180_RS05340	COG1879	ABC-type sugar transport system periplasmic component
LY180_RS05345	COG0745	RESPONSE REGULATOR receiver
LY180_RS05350	COG3005	denitrification pathway
LY180_RS05355	COG0243	molybdopterin cofactor binding
LY180_RS05405	COG3729	General stress protein
LY180_RS05410	COG2233	PERMEase
LY180_RS05445	COG1309	transcriptional regulator
LY180_RS05450	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LY180_RS05450	COG0506	proline dehydrogenase activity
LY180_RS05450	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LY180_RS05460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LY180_RS05475	COG2822	iron ion transport
LY180_RS05490	COG1702	phosphate starvation-inducible protein PhoH
LY180_RS05495	COG3658	cytochrome
LY180_RS05500	COG1215	transferase activity, transferring glycosyl groups
LY180_RS05505	COG0726	polysaccharide deacetylase
LY180_RS05505	COG1649	PFAM Uncharacterised BCR, COG1649
LY180_RS05510	COG0457	Tetratricopeptide repeat
LY180_RS05525	COG3381	protein complex oligomerization
LY180_RS05535	COG1462	curli production assembly transport component CsgG
LY180_RS05550	COG2197	response regulator
LY180_RS05580	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LY180_RS05585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LY180_RS05610	COG2943	transferase activity, transferring hexosyl groups
LY180_RS05615	COG5645	(Lipo)protein
LY180_RS05635	COG1560	Kdo2-lipid A biosynthetic process
LY180_RS05645	COG2353	YceI-like domain
LY180_RS05650	COG3038	cytochrome b561
LY180_RS05685	COG2999	glutathione oxidoreductase activity
LY180_RS05695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LY180_RS05705	COG0673	inositol 2-dehydrogenase activity
LY180_RS05710	COG0728	peptidoglycan biosynthetic process
LY180_RS05715	COG3418	PFAM FlgN family protein
LY180_RS05720	COG2747	anti-sigma28 factor FlgM
LY180_RS05725	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
LY180_RS05730	COG1815	bacterial-type flagellum-dependent cell motility
LY180_RS05735	COG1558	bacterial-type flagellum-dependent cell motility
LY180_RS05740	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LY180_RS05745	COG1749	Flagellar hook protein flgE
LY180_RS05750	COG4787	bacterial-type flagellum-dependent cell motility
LY180_RS05755	COG4786	Flagellar basal body rod
LY180_RS05770	COG3951	Flagellar rod assembly protein muramidase FlgJ
LY180_RS05770	COG1705	Flagellar rod assembly protein muramidase FlgJ
LY180_RS05775	COG1256	bacterial-type flagellum assembly
LY180_RS05780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LY180_RS05785	COG1530	ribonuclease E activity
LY180_RS05795	COG0564	pseudouridine synthase activity
LY180_RS05800	COG0424	maF-like protein
LY180_RS05805	COG1399	metal-binding, possibly nucleic acid-binding protein
LY180_RS05825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LY180_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS05840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LY180_RS05845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LY180_RS05850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LY180_RS05860	COG0470	DNA polymerase III
LY180_RS05865	COG0084	hydrolase, TatD family'
LY180_RS05870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS05870	COG1263	PTS System
LY180_RS05875	COG4773	Receptor
LY180_RS05880	COG0537	adenosine 5'-monophosphoramidase activity
LY180_RS05885	COG5633	Lipoprotein
LY180_RS05890	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LY180_RS05910	COG1252	NADH dehydrogenase
LY180_RS05915	COG3134	Outer membrane lipoprotein
LY180_RS05920	COG1309	transcriptional regulator
LY180_RS05930	COG1388	LysM domain
LY180_RS05930	COG1376	ErfK ybiS ycfS ynhG family protein
LY180_RS05935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LY180_RS05940	COG4763	Acyl-transferase
LY180_RS05945	COG4591	ABC-type transport system involved in lipoprotein release permease component
LY180_RS05955	COG4591	ABC-type transport system involved in lipoprotein release permease component
LY180_RS05965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LY180_RS05970	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LY180_RS05980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LY180_RS05985	COG1177	transmembrane transport
LY180_RS05995	COG3842	ATPase activity
LY180_RS06010	COG2850	peptidyl-arginine hydroxylation
LY180_RS06015	COG2205	protein histidine kinase activity
LY180_RS06025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LY180_RS06045	COG1187	pseudouridine synthase activity
LY180_RS06050	COG0538	isocitrate dehydrogenase activity
LY180_RS06065	COG5562	phage envelope protein
LY180_RS06070	COG0789	Transcriptional regulator
LY180_RS06075	COG2200	EAL domain
LY180_RS06100	COG2200	EAL domain
LY180_RS06150	COG2894	cell division
LY180_RS06180	COG0179	Fumarylacetoacetate (FAA) hydrolase
LY180_RS06200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LY180_RS06205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LY180_RS06225	COG2719	SpoVR family
LY180_RS06235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LY180_RS06245	COG1619	proteins homologs of microcin C7 resistance protein MccF
LY180_RS06255	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LY180_RS06275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS06275	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LY180_RS06275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LY180_RS06280	COG1461	Dihydroxyacetone kinase
LY180_RS06285	COG2376	Dihydroxyacetone kinase
LY180_RS06290	COG3284	Transcriptional regulator
LY180_RS06295	COG3468	outer membrane autotransporter barrel domain protein
LY180_RS06305	COG0012	GTP binding
LY180_RS06320	COG0659	secondary active sulfate transmembrane transporter activity
LY180_RS06325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LY180_RS06350	COG2890	protein-(glutamine-N5) methyltransferase activity
LY180_RS06355	COG3094	Invasion gene expression up-regulator, SirB
LY180_RS06360	COG2912	Transglutaminase-like superfamily
LY180_RS06385	COG0387	Pfam Sodium calcium exchanger
LY180_RS06395	COG4572	Cation transport regulator
LY180_RS06400	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LY180_RS06405	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LY180_RS06410	COG4932	domain protein
LY180_RS06415	COG2197	response regulator
LY180_RS06420	COG3850	Histidine kinase
LY180_RS06430	COG2223	nitrite transmembrane transporter activity
LY180_RS06435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LY180_RS06440	COG1140	nitrate reductase beta subunit
LY180_RS06445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LY180_RS06450	COG2181	nitrate reductase activity
LY180_RS06470	COG0788	formyltetrahydrofolate deformylase activity
LY180_RS06480	COG1752	Esterase of the alpha-beta hydrolase superfamily
LY180_RS06485	COG0745	RESPONSE REGULATOR receiver
LY180_RS06490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LY180_RS06500	COG1435	thymidine kinase activity
LY180_RS06505	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS06505	COG1454	alcohol dehydrogenase
LY180_RS06515	COG1454	alcohol dehydrogenase
LY180_RS06515	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS06520	COG2095	MarC family integral membrane protein
LY180_RS06525	COG4166	transmembrane transport
LY180_RS06530	COG0601	transmembrane transport
LY180_RS06535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LY180_RS06540	COG0444	Belongs to the ABC transporter superfamily
LY180_RS06545	COG4608	Belongs to the ABC transporter superfamily
LY180_RS06565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LY180_RS06570	COG2350	Protein conserved in bacteria
LY180_RS06575	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LY180_RS06580	COG1607	acyl-coa hydrolase
LY180_RS06595	COG3047	cAMP biosynthetic process
LY180_RS06600	COG3685	Protein conserved in bacteria
LY180_RS06605	COG3685	Protein conserved in bacteria
LY180_RS06610	COG3729	General stress protein
LY180_RS06625	COG0134	indole-3-glycerol-phosphate synthase activity
LY180_RS06625	COG0135	phosphoribosylanthranilate isomerase activity
LY180_RS06630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LY180_RS06630	COG0512	Glutamine amidotransferase of anthranilate synthase
LY180_RS06635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LY180_RS06640	COG0613	PHP domain protein
LY180_RS06645	COG0009	L-threonylcarbamoyladenylate synthase
LY180_RS06650	COG1187	pseudouridine synthase activity
LY180_RS06655	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LY180_RS06660	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS06670	COG0616	signal peptide processing
LY180_RS06685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LY180_RS06690	COG0583	DNA-binding transcription factor activity
LY180_RS06715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LY180_RS06725	COG0671	phosphoesterase, PA-phosphatase related
LY180_RS06730	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LY180_RS06735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LY180_RS06745	COG0023	Translation Initiation Factor
LY180_RS06755	COG1349	DNA-binding transcription factor activity
LY180_RS06765	COG5001	Diguanylate cyclase
LY180_RS06780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LY180_RS06780	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LY180_RS06785	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LY180_RS06795	COG2852	Protein conserved in bacteria
LY180_RS06800	COG4172	Belongs to the ABC transporter superfamily
LY180_RS06805	COG4172	Belongs to the ABC transporter superfamily
LY180_RS06810	COG4171	peptide transport system, permease
LY180_RS06815	COG4168	peptide transport system, permease
LY180_RS06820	COG4166	transmembrane transport
LY180_RS06835	COG0531	amino acid
LY180_RS06840	COG0174	glutamine synthetase
LY180_RS06845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LY180_RS06850	COG1917	Cupin 2, conserved barrel domain protein
LY180_RS06850	COG1396	sequence-specific DNA binding
LY180_RS06855	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS06860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LY180_RS06865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LY180_RS06870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LY180_RS06875	COG1842	Phage shock protein A
LY180_RS06885	COG1983	PspC domain protein
LY180_RS06895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LY180_RS06900	COG0366	Alpha amylase catalytic
LY180_RS06905	COG1653	transport
LY180_RS06910	COG1175	transmembrane transport
LY180_RS06915	COG0395	ABC-type sugar transport system, permease component
LY180_RS06920	COG1063	alcohol dehydrogenase
LY180_RS06925	COG1082	Xylose isomerase domain protein TIM barrel
LY180_RS06930	COG0673	inositol 2-dehydrogenase activity
LY180_RS06935	COG1554	hydrolase, family 65, central catalytic
LY180_RS06940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LY180_RS06945	COG3842	ATPase activity
LY180_RS06955	COG1609	Transcriptional regulator
LY180_RS06960	COG3106	COG3106 Predicted ATPase
LY180_RS06970	COG3283	Transcriptional regulator of aromatic amino acids metabolism
LY180_RS06975	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LY180_RS06980	COG4948	Mandelate Racemase Muconate Lactonizing
LY180_RS06985	COG2866	Carboxypeptidase
LY180_RS06990	COG0702	epimerase
LY180_RS06995	COG1073	alpha beta
LY180_RS07000	COG1073	alpha beta
LY180_RS07005	COG0583	DNA-binding transcription factor activity
LY180_RS07010	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LY180_RS07015	COG4166	transmembrane transport
LY180_RS07020	COG0668	transmembrane transport
LY180_RS07025	COG3182	Iron-regulated membrane protein
LY180_RS07030	COG0589	response to stress
LY180_RS07035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LY180_RS07040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LY180_RS07045	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LY180_RS07055	COG1473	amidohydrolase
LY180_RS07060	COG1473	amidohydrolase
LY180_RS07065	COG0583	DNA-binding transcription factor activity
LY180_RS07070	COG2840	Smr protein MutS2
LY180_RS07075	COG3706	GGDEF domain
LY180_RS07090	COG0513	Belongs to the DEAD box helicase family
LY180_RS07100	COG0582	viral genome integration into host DNA
LY180_RS07120	COG3723	Recombinational DNA repair protein, rece pathway
LY180_RS07125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LY180_RS07165	COG3756	Protein conserved in bacteria
LY180_RS07170	COG1484	DNA-dependent DNA replication
LY180_RS07175	COG1846	Transcriptional regulator
LY180_RS07250	COG1475	DNA binding
LY180_RS07400	COG5301	cellulose 1,4-beta-cellobiosidase activity
LY180_RS07410	COG0589	response to stress
LY180_RS07415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LY180_RS07420	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LY180_RS07420	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LY180_RS07420	COG0674	pyruvate-flavodoxin oxidoreductase activity
LY180_RS07420	COG1013	pyruvate-flavodoxin oxidoreductase activity
LY180_RS07425	COG3042	response to heat
LY180_RS07430	COG3187	Heat shock protein
LY180_RS07435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LY180_RS07440	COG2723	6-phospho-beta-galactosidase activity
LY180_RS07450	COG0439	Biotin carboxylase
LY180_RS07455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LY180_RS07460	COG2911	Protein conserved in bacteria
LY180_RS07470	COG3784	Protein of unknown function (DUF1318)
LY180_RS07475	COG2207	Transcriptional regulator
LY180_RS07480	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS07485	COG3733	amine oxidase
LY180_RS07490	COG2030	dehydratase
LY180_RS07490	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS07495	COG3396	Phenylacetate-CoA oxygenase
LY180_RS07500	COG3460	Phenylacetate-CoA oxygenase
LY180_RS07505	COG3396	Phenylacetate-CoA oxygenase
LY180_RS07510	COG2151	metal-sulfur cluster biosynthetic enzyme
LY180_RS07515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LY180_RS07520	COG1024	Enoyl-CoA hydratase
LY180_RS07525	COG1024	Enoyl-CoA hydratase
LY180_RS07530	COG1250	3-hydroxyacyl-CoA dehydrogenase
LY180_RS07535	COG2050	protein possibly involved in aromatic compounds catabolism
LY180_RS07540	COG0183	Belongs to the thiolase family
LY180_RS07545	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LY180_RS07550	COG3327	negative regulation of DNA-templated transcription, initiation
LY180_RS07555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LY180_RS07560	COG0667	Aldo Keto reductase
LY180_RS07570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LY180_RS07575	COG4589	Belongs to the CDS family
LY180_RS07580	COG2267	carboxylic ester hydrolase activity
LY180_RS07585	COG2453	phosphatase
LY180_RS07585	COG0671	phosphoesterase, PA-phosphatase related
LY180_RS07595	COG1643	Atp-dependent helicase
LY180_RS07600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LY180_RS07605	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS07610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LY180_RS07615	COG3038	cytochrome b561
LY180_RS07630	COG0840	transmembrane signaling receptor activity
LY180_RS07635	COG0583	DNA-binding transcription factor activity
LY180_RS07640	COG5383	Protein conserved in bacteria
LY180_RS07655	COG2841	Protein conserved in bacteria
LY180_RS07660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LY180_RS07665	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LY180_RS07670	COG1275	C4-dicarboxylate transporter malic acid transport protein
LY180_RS07675	COG0500	methyltransferase
LY180_RS07695	COG0675	Transposase, IS605 OrfB family
LY180_RS07700	COG3135	benzoate transporter
LY180_RS07705	COG1396	sequence-specific DNA binding
LY180_RS07710	COG0826	peptidase U32
LY180_RS07720	COG1724	mRNA binding
LY180_RS07725	COG1598	PFAM Uncharacterised protein family UPF0150
LY180_RS07730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LY180_RS07735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LY180_RS07740	COG3842	ATPase activity
LY180_RS07745	COG1176	ABC-type spermidine putrescine transport system, permease component I
LY180_RS07750	COG1177	transmembrane transport
LY180_RS07775	COG3238	Protein conserved in bacteria
LY180_RS07780	COG1247	-acetyltransferase
LY180_RS07785	COG2130	NADP-dependent
LY180_RS07790	COG1802	Transcriptional regulator
LY180_RS07795	COG4772	TonB-dependent receptor
LY180_RS07800	COG3391	amine dehydrogenase activity
LY180_RS07805	COG1113	amino acid transport
LY180_RS07810	COG0625	glutathione transferase activity
LY180_RS07825	COG3209	COG3209 Rhs family protein
LY180_RS07835	COG5433	transposase activity
LY180_RS07845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LY180_RS07850	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LY180_RS07855	COG0384	phenazine biosynthesis protein PhzF
LY180_RS07860	COG2181	nitrate reductase activity
LY180_RS07865	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LY180_RS07870	COG1140	nitrate reductase beta subunit
LY180_RS07875	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LY180_RS07880	COG2223	nitrite transmembrane transporter activity
LY180_RS07885	COG4886	Leucine-rich repeat (LRR) protein
LY180_RS07890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LY180_RS07895	COG0697	spore germination
LY180_RS07900	COG3383	formate dehydrogenase (NAD+) activity
LY180_RS07900	COG0243	molybdopterin cofactor binding
LY180_RS07905	COG3383	formate dehydrogenase (NAD+) activity
LY180_RS07905	COG0243	molybdopterin cofactor binding
LY180_RS07910	COG0437	4 iron, 4 sulfur cluster binding
LY180_RS07915	COG2864	formate dehydrogenase
LY180_RS07920	COG3093	addiction module antidote protein HigA
LY180_RS07925	COG1064	alcohol dehydrogenase
LY180_RS07945	COG1764	response to oxidative stress
LY180_RS07950	COG4608	Belongs to the ABC transporter superfamily
LY180_RS07955	COG0444	Belongs to the ABC transporter superfamily
LY180_RS07960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LY180_RS07965	COG0601	transmembrane transport
LY180_RS07970	COG0747	negative chemotaxis
LY180_RS07980	COG2199	diguanylate cyclase activity
LY180_RS07980	COG2200	EAL domain
LY180_RS07980	COG2202	Pas domain
LY180_RS07990	COG1649	PFAM Uncharacterised BCR, COG1649
LY180_RS07995	COG0531	amino acid
LY180_RS08000	COG0076	glutamate decarboxylase activity
LY180_RS08010	COG0612	Peptidase, M16
LY180_RS08015	COG4771	TonB-dependent receptor
LY180_RS08020	COG4178	(ABC) transporter
LY180_RS08025	COG0641	radical SAM
LY180_RS08030	COG3119	arylsulfatase activity
LY180_RS08045	COG3119	arylsulfatase activity
LY180_RS08050	COG2207	Transcriptional regulator
LY180_RS08060	COG0243	molybdopterin cofactor binding
LY180_RS08065	COG3539	Fimbrial protein
LY180_RS08070	COG3539	Fimbrial protein
LY180_RS08075	COG3539	Fimbrial protein
LY180_RS08080	COG3188	usher protein
LY180_RS08090	COG3539	Fimbrial protein
LY180_RS08095	COG4977	sequence-specific DNA binding
LY180_RS08100	COG3550	peptidyl-serine autophosphorylation
LY180_RS08105	COG1396	sequence-specific DNA binding
LY180_RS08110	COG2911	Protein conserved in bacteria
LY180_RS08110	COG3210	domain, Protein
LY180_RS08125	COG1447	Phosphotransferase system cellobiose-specific component IIA
LY180_RS08130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LY180_RS08140	COG2188	Transcriptional regulator
LY180_RS08145	COG0697	spore germination
LY180_RS08150	COG2814	Major facilitator Superfamily
LY180_RS08160	COG3706	GGDEF domain
LY180_RS08165	COG3111	PFAM Bacterial OB fold (BOF) protein
LY180_RS08170	COG1546	Belongs to the CinA family
LY180_RS08175	COG0339	signal peptide processing
LY180_RS08180	COG4221	oxidoreductase activity
LY180_RS08185	COG1802	Transcriptional regulator
LY180_RS08195	COG0246	Mannitol dehydrogenase
LY180_RS08200	COG0477	Major facilitator Superfamily
LY180_RS08215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LY180_RS08220	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LY180_RS08225	COG5301	cellulose 1,4-beta-cellobiosidase activity
LY180_RS08270	COG1196	nuclear chromosome segregation
LY180_RS08320	COG1030	water channel activity
LY180_RS08340	COG4220	transposase activity
LY180_RS08360	COG5562	phage envelope protein
LY180_RS08375	COG1278	Cold shock
LY180_RS08385	COG3772	lysozyme
LY180_RS08400	COG1278	Cold shock
LY180_RS08405	COG1278	Cold shock
LY180_RS08410	COG0484	heat shock protein binding
LY180_RS08415	COG1403	HNH endonuclease
LY180_RS08435	COG2026	Addiction module toxin, RelE StbE family
LY180_RS08440	COG3077	Addiction module antitoxin, RelB DinJ family
LY180_RS08450	COG2801	Transposase and inactivated derivatives
LY180_RS08475	COG1846	Transcriptional regulator
LY180_RS08490	COG1396	sequence-specific DNA binding
LY180_RS08520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LY180_RS08530	COG0582	viral genome integration into host DNA
LY180_RS08540	COG1063	alcohol dehydrogenase
LY180_RS08545	COG4948	Mandelate Racemase Muconate Lactonizing
LY180_RS08560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LY180_RS08575	COG0243	molybdopterin cofactor binding
LY180_RS08580	COG0243	molybdopterin cofactor binding
LY180_RS08585	COG0437	4 iron, 4 sulfur cluster binding
LY180_RS08590	COG3302	dmso reductase anchor subunit
LY180_RS08595	COG3381	protein complex oligomerization
LY180_RS08605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LY180_RS08610	COG1940	carbohydrate kinase activity
LY180_RS08615	COG1662	PFAM IS1 transposase
LY180_RS08620	COG1662	PFAM IS1 transposase
LY180_RS08620	COG3677	Transposase
LY180_RS08625	COG1940	carbohydrate kinase activity
LY180_RS08630	COG0583	DNA-binding transcription factor activity
LY180_RS08635	COG2814	Major facilitator Superfamily
LY180_RS08650	COG3591	Belongs to the peptidase S1B family
LY180_RS08665	COG0628	permease
LY180_RS08670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LY180_RS08675	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LY180_RS08685	COG0531	amino acid
LY180_RS08695	COG3136	membrane protein required for alginate biosynthesis
LY180_RS08700	COG0745	RESPONSE REGULATOR receiver
LY180_RS08705	COG2205	protein histidine kinase activity
LY180_RS08715	COG0114	fumarate hydratase activity
LY180_RS08720	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LY180_RS08720	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LY180_RS08725	COG1482	cell wall glycoprotein biosynthetic process
LY180_RS08730	COG5339	Protein conserved in bacteria
LY180_RS08745	COG3250	beta-galactosidase activity
LY180_RS08750	COG1309	transcriptional regulator
LY180_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS08765	COG1609	Transcriptional regulator
LY180_RS08770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS08770	COG1263	PTS System
LY180_RS08775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LY180_RS08785	COG0673	inositol 2-dehydrogenase activity
LY180_RS08825	COG4659	FMN binding
LY180_RS08835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LY180_RS08845	COG3104	oligopeptide transport
LY180_RS08850	COG0625	glutathione transferase activity
LY180_RS08855	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LY180_RS08870	COG3895	Periplasmic Protein
LY180_RS08880	COG3133	Outer membrane lipoprotein
LY180_RS08895	COG1566	PFAM secretion protein HlyD family protein
LY180_RS08900	COG1289	transmembrane transporter activity
LY180_RS08905	COG2032	superoxide dismutase activity
LY180_RS08910	COG4989	oxidoreductase activity
LY180_RS08915	COG3313	Fe-S protein
LY180_RS08920	COG1309	transcriptional regulator
LY180_RS08925	COG1902	pentaerythritol trinitrate reductase activity
LY180_RS08930	COG0346	lactoylglutathione lyase activity
LY180_RS08940	COG1201	RNA secondary structure unwinding
LY180_RS08945	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LY180_RS08950	COG0791	NLP P60 protein
LY180_RS08955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LY180_RS08960	COG2814	Major facilitator Superfamily
LY180_RS08975	COG0583	DNA-binding transcription factor activity
LY180_RS08980	COG2814	Major facilitator Superfamily
LY180_RS08985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LY180_RS08990	COG0307	riboflavin synthase, alpha
LY180_RS09000	COG3468	outer membrane autotransporter barrel domain protein
LY180_RS09020	COG4529	Protein conserved in bacteria
LY180_RS09030	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LY180_RS09035	COG0437	4 iron, 4 sulfur cluster binding
LY180_RS09045	COG2414	aldehyde ferredoxin oxidoreductase
LY180_RS09050	COG0437	4 iron, 4 sulfur cluster binding
LY180_RS09060	COG0469	pyruvate kinase activity
LY180_RS09065	COG4238	major outer membrane lipoprotein
LY180_RS09070	COG1376	ErfK ybiS ycfS ynhG family protein
LY180_RS09085	COG0719	Fe-S assembly protein
LY180_RS09090	COG0396	ATPase activity
LY180_RS09095	COG0719	Fe-S assembly protein
LY180_RS09100	COG0316	Belongs to the HesB IscA family
LY180_RS09110	COG2050	protein possibly involved in aromatic compounds catabolism
LY180_RS09115	COG0277	FAD linked oxidase domain protein
LY180_RS09115	COG0247	lactate metabolic process
LY180_RS09120	COG0628	permease
LY180_RS09130	COG0738	Major facilitator superfamily
LY180_RS09135	COG2271	Major facilitator Superfamily
LY180_RS09150	COG4670	ketone body catabolic process
LY180_RS09155	COG1960	acyl-CoA dehydrogenase activity
LY180_RS09160	COG2207	Transcriptional regulator
LY180_RS09160	COG1917	Cupin 2, conserved barrel domain protein
LY180_RS09170	COG2086	electron transfer activity
LY180_RS09175	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LY180_RS09180	COG0644	oxidoreductase
LY180_RS09185	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LY180_RS09190	COG0318	PFAM AMP-dependent synthetase and ligase
LY180_RS09195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LY180_RS09195	COG0574	Belongs to the PEP-utilizing enzyme family
LY180_RS09210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LY180_RS09215	COG4256	Hemin uptake protein
LY180_RS09225	COG2200	EAL domain
LY180_RS09230	COG0791	NLP P60 protein
LY180_RS09240	COG0386	Belongs to the glutathione peroxidase family
LY180_RS09310	COG3137	Salt-induced outer membrane protein
LY180_RS09315	COG1105	Belongs to the carbohydrate kinase PfkB family
LY180_RS09325	COG3001	Fructosamine kinase
LY180_RS09335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LY180_RS09340	COG1988	membrane-bound metal-dependent
LY180_RS09345	COG1823	symporter activity
LY180_RS09365	COG0753	catalase activity
LY180_RS09375	COG1486	melibiose metabolic process
LY180_RS09380	COG2169	Transcriptional regulator
LY180_RS09380	COG1917	Cupin 2, conserved barrel domain protein
LY180_RS09385	COG1447	Phosphotransferase system cellobiose-specific component IIA
LY180_RS09390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LY180_RS09395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LY180_RS09400	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LY180_RS09415	COG0322	excinuclease ABC activity
LY180_RS09425	COG3678	ATP-independent chaperone mediated protein folding
LY180_RS09455	COG0708	Exodeoxyribonuclease III
LY180_RS09460	COG0398	Pfam SNARE associated Golgi protein
LY180_RS09470	COG0398	Pfam SNARE associated Golgi protein
LY180_RS09475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LY180_RS09480	COG4134	Bacterial extracellular solute-binding protein
LY180_RS09485	COG4135	transport system, permease component
LY180_RS09490	COG4136	ATPase activity
LY180_RS09495	COG2897	thiosulfate sulfurtransferase activity
LY180_RS09500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LY180_RS09505	COG0494	nUDIX hydrolase
LY180_RS09515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LY180_RS09525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LY180_RS09530	COG0709	Synthesizes selenophosphate from selenide and ATP
LY180_RS09540	COG0778	Nitroreductase
LY180_RS09550	COG0616	signal peptide processing
LY180_RS09555	COG0252	asparaginase activity
LY180_RS09560	COG1335	isochorismatase
LY180_RS09565	COG2814	Major facilitator Superfamily
LY180_RS09570	COG1349	DNA-binding transcription factor activity
LY180_RS09575	COG0667	Aldo Keto reductase
LY180_RS09580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LY180_RS09585	COG0191	fructose-bisphosphate aldolase activity
LY180_RS09590	COG1063	alcohol dehydrogenase
LY180_RS09595	COG2271	Major facilitator Superfamily
LY180_RS09600	COG1063	alcohol dehydrogenase
LY180_RS09605	COG3139	Protein of unknown function (DUF1315)
LY180_RS09615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LY180_RS09620	COG0676	glucose-6-phosphate 1-epimerase activity
LY180_RS09625	COG0656	L-ascorbic acid biosynthetic process
LY180_RS09630	COG3713	MltA-interacting MipA family protein
LY180_RS09635	COG2766	serine protein kinase
LY180_RS09645	COG2199	diguanylate cyclase activity
LY180_RS09650	COG2199	diguanylate cyclase activity
LY180_RS09655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LY180_RS09670	COG2207	Transcriptional regulator
LY180_RS09675	COG2807	transmembrane transport
LY180_RS09680	COG3189	MarR family transcriptional regulator
LY180_RS09685	COG3042	response to heat
LY180_RS09690	COG2199	diguanylate cyclase activity
LY180_RS09690	COG2203	Gaf domain
LY180_RS09700	COG2261	transglycosylase associated protein
LY180_RS09705	COG0675	Transposase, IS605 OrfB family
LY180_RS09720	COG3615	Tellurite resistance protein tehB
LY180_RS09730	COG0583	DNA-binding transcription factor activity
LY180_RS09735	COG0473	3-isopropylmalate dehydrogenase activity
LY180_RS09740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LY180_RS09745	COG4638	Rieske (2fe-2S)
LY180_RS09750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LY180_RS09755	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LY180_RS09760	COG0318	PFAM AMP-dependent synthetase and ligase
LY180_RS09765	COG3065	identical protein binding
LY180_RS09770	COG1214	PFAM Peptidase M22, glycoprotease
LY180_RS09775	COG1199	ATP-dependent helicase activity
LY180_RS09780	COG0251	oxidation-reduction process
LY180_RS09795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LY180_RS09805	COG1760	l-serine dehydratase
LY180_RS09810	COG2200	EAL domain
LY180_RS09815	COG1253	flavin adenine dinucleotide binding
LY180_RS09825	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS09825	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS09830	COG3715	PTS system
LY180_RS09835	COG3716	PTS system mannose fructose sorbose family IID component
LY180_RS09855	COG2226	methyltransferase
LY180_RS09890	COG1414	Transcriptional regulator
LY180_RS09895	COG2814	Major facilitator Superfamily
LY180_RS09905	COG0793	Belongs to the peptidase S41A family
LY180_RS09915	COG1956	GAF domain-containing protein
LY180_RS09920	COG2995	paraquat-inducible protein a
LY180_RS09925	COG3008	intermembrane lipid transfer
LY180_RS09945	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LY180_RS09960	COG1276	copper resistance
LY180_RS09965	COG2372	response to copper ion
LY180_RS09975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LY180_RS09980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LY180_RS09985	COG1770	oligopeptidase
LY180_RS09990	COG2979	Protein of unknown function (DUF533)
LY180_RS10005	COG3141	response to X-ray
LY180_RS10015	COG0800	Aldolase
LY180_RS10020	COG0129	dihydroxy-acid dehydratase activity
LY180_RS10025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LY180_RS10035	COG1737	Transcriptional regulator
LY180_RS10040	COG0469	pyruvate kinase activity
LY180_RS10045	COG1560	Kdo2-lipid A biosynthetic process
LY180_RS10050	COG0739	heme binding
LY180_RS10055	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LY180_RS10065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LY180_RS10070	COG3547	Transposase (IS116 IS110 IS902 family)
LY180_RS10095	COG0217	transcriptional regulatory protein
LY180_RS10100	COG0494	nUDIX hydrolase
LY180_RS10110	COG1335	isochorismatase
LY180_RS10115	COG1801	Protein of unknown function DUF72
LY180_RS10120	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LY180_RS10135	COG0243	molybdopterin cofactor binding
LY180_RS10140	COG3005	denitrification pathway
LY180_RS10150	COG3102	Protein conserved in bacteria
LY180_RS10160	COG3755	Protein conserved in bacteria
LY180_RS10170	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LY180_RS10175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LY180_RS10180	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LY180_RS10185	COG0745	RESPONSE REGULATOR receiver
LY180_RS10190	COG2201	protein-glutamate methylesterase activity
LY180_RS10195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LY180_RS10200	COG0840	transmembrane signaling receptor activity
LY180_RS10205	COG0840	transmembrane signaling receptor activity
LY180_RS10210	COG0835	chemotaxis
LY180_RS10215	COG2198	Histidine kinase
LY180_RS10215	COG0643	Histidine kinase
LY180_RS10220	COG1360	Flagellar Motor Protein
LY180_RS10225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LY180_RS10240	COG0589	response to stress
LY180_RS10250	COG1877	trehalose-phosphatase activity
LY180_RS10255	COG1172	Belongs to the binding-protein-dependent transport system permease family
LY180_RS10260	COG1129	ABC transporter
LY180_RS10265	COG1879	ABC-type sugar transport system periplasmic component
LY180_RS10270	COG1528	Iron-storage protein
LY180_RS10290	COG1528	Iron-storage protein
LY180_RS10300	COG0814	amino acid
LY180_RS10305	COG3318	Belongs to the UPF0149 family
LY180_RS10305	COG3012	SEC-C Motif Domain Protein
LY180_RS10335	COG2197	response regulator
LY180_RS10350	COG2197	response regulator
LY180_RS10355	COG1126	abc transporter atp-binding protein
LY180_RS10360	COG0765	amino acid transport
LY180_RS10370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LY180_RS10380	COG1191	sigma factor activity
LY180_RS10395	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LY180_RS10400	COG1516	flagellar protein fliS
LY180_RS10410	COG0366	Alpha amylase catalytic
LY180_RS10420	COG2391	methyltransferase activity
LY180_RS10425	COG0425	Belongs to the sulfur carrier protein TusA family
LY180_RS10435	COG0675	Transposase, IS605 OrfB family
LY180_RS10445	COG2207	Transcriptional regulator
LY180_RS10450	COG1881	PFAM PEBP family protein
LY180_RS10455	COG2076	Multidrug Resistance protein
LY180_RS10470	COG1766	The M ring may be actively involved in energy transduction
LY180_RS10475	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LY180_RS10480	COG1317	bacterial-type flagellum organization
LY180_RS10485	COG1157	protein secretion by the type III secretion system
LY180_RS10490	COG2882	bacterial-type flagellum organization
LY180_RS10495	COG3144	bacterial-type flagellum assembly
LY180_RS10500	COG1580	Controls the rotational direction of flagella during chemotaxis
LY180_RS10505	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LY180_RS10510	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LY180_RS10515	COG3190	flagellar
LY180_RS10520	COG1338	Plays a role in the flagellum-specific transport system
LY180_RS10525	COG1987	bacterial-type flagellum assembly
LY180_RS10530	COG1684	flagellar biosynthetic protein fliR
LY180_RS10535	COG2197	response regulator
LY180_RS10560	COG5475	Uncharacterized small protein (DUF2158)
LY180_RS10565	COG2354	Protein conserved in bacteria
LY180_RS10570	COG0697	spore germination
LY180_RS10575	COG3727	T/G mismatch-specific endonuclease activity
LY180_RS10580	COG0270	DNA (cytosine-5-)-methyltransferase activity
LY180_RS10585	COG1418	mRNA catabolic process
LY180_RS10600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LY180_RS10615	COG2205	protein histidine kinase activity
LY180_RS10620	COG0745	RESPONSE REGULATOR receiver
LY180_RS10625	COG2351	hydroxyisourate hydrolase activity
LY180_RS10640	COG3443	Belongs to the bacterial solute-binding protein 9 family
LY180_RS10645	COG3038	cytochrome b561
LY180_RS10695	COG0477	Major facilitator Superfamily
LY180_RS10700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LY180_RS10705	COG0217	transcriptional regulatory protein
LY180_RS10725	COG0534	Mate efflux family protein
LY180_RS10735	COG0583	DNA-binding transcription factor activity
LY180_RS10740	COG0583	DNA-binding transcription factor activity
LY180_RS10750	COG1376	ErfK ybiS ycfS ynhG family protein
LY180_RS10765	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
LY180_RS10770	COG4917	ethanolamine utilization protein
LY180_RS10780	COG1289	transmembrane transporter activity
LY180_RS10790	COG1686	Belongs to the peptidase S11 family
LY180_RS10795	COG2925	Exonuclease
LY180_RS10800	COG0425	Belongs to the sulfur carrier protein TusA family
LY180_RS10805	COG2391	methyltransferase activity
LY180_RS10810	COG0531	amino acid
LY180_RS10815	COG0583	DNA-binding transcription factor activity
LY180_RS10820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LY180_RS10825	COG4115	mRNA cleavage
LY180_RS10830	COG2161	toxin-antitoxin pair type II binding
LY180_RS10850	COG0131	Imidazoleglycerol-phosphate dehydratase
LY180_RS10850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LY180_RS10855	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LY180_RS10880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LY180_RS10885	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LY180_RS10890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LY180_RS10905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LY180_RS10920	COG1216	Glycosyl transferase, family 2
LY180_RS10935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LY180_RS10945	COG0438	transferase activity, transferring glycosyl groups
LY180_RS10950	COG2327	Polysaccharide pyruvyl transferase
LY180_RS10955	COG2244	polysaccharide biosynthetic process
LY180_RS10960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LY180_RS10965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LY180_RS10970	COG0662	Cupin 2, conserved barrel domain protein
LY180_RS10970	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LY180_RS10975	COG0297	glycogen (starch) synthase activity
LY180_RS10980	COG1051	belongs to the nudix hydrolase family
LY180_RS10985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LY180_RS10990	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LY180_RS10995	COG0110	maltose O-acetyltransferase activity
LY180_RS11000	COG1216	Glycosyl transferase, family 2
LY180_RS11010	COG0438	transferase activity, transferring glycosyl groups
LY180_RS11015	COG1045	serine acetyltransferase
LY180_RS11020	COG0463	Glycosyl transferase, family 2
LY180_RS11025	COG0489	protein tyrosine kinase activity
LY180_RS11025	COG3206	protein involved in exopolysaccharide biosynthesis
LY180_RS11030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LY180_RS11035	COG1596	polysaccharide export
LY180_RS11040	COG1253	flavin adenine dinucleotide binding
LY180_RS11055	COG2982	Protein involved in outer membrane biogenesis
LY180_RS11065	COG0572	uridine kinase
LY180_RS11070	COG5002	protein histidine kinase activity
LY180_RS11070	COG5001	Diguanylate cyclase
LY180_RS11070	COG3447	MASE1 domain protein
LY180_RS11075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LY180_RS11080	COG0443	Heat shock 70 kDa protein
LY180_RS11085	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
LY180_RS11090	COG3779	Protein conserved in bacteria
LY180_RS11095	COG0631	protein serine/threonine phosphatase activity
LY180_RS11100	COG4245	von Willebrand factor, type A
LY180_RS11125	COG2205	protein histidine kinase activity
LY180_RS11130	COG0745	RESPONSE REGULATOR receiver
LY180_RS11140	COG3609	addiction module antidote protein, CC2985 family
LY180_RS11150	COG0826	peptidase U32
LY180_RS11195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LY180_RS11210	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LY180_RS11305	COG4695	Portal protein
LY180_RS11350	COG4974	Belongs to the 'phage' integrase family
LY180_RS11375	COG1063	alcohol dehydrogenase
LY180_RS11380	COG3775	system Galactitol-specific IIC component
LY180_RS11385	COG3414	Phosphotransferase system galactitol-specific IIB component
LY180_RS11390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS11405	COG1830	Aldolase
LY180_RS11410	COG2211	Major facilitator Superfamily
LY180_RS11415	COG1397	ADP-ribosylglycohydrolase
LY180_RS11420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LY180_RS11425	COG2188	Transcriptional regulator
LY180_RS11430	COG3757	hydrolase, family 25
LY180_RS11435	COG0351	phosphomethylpyrimidine kinase
LY180_RS11455	COG5455	response to cobalt ion
LY180_RS11460	COG3539	Fimbrial protein
LY180_RS11465	COG3188	usher protein
LY180_RS11470	COG3121	Chaperone
LY180_RS11475	COG3539	Fimbrial protein
LY180_RS11490	COG0489	protein tyrosine kinase activity
LY180_RS11500	COG3831	ATPase activity
LY180_RS11505	COG3831	ATPase activity
LY180_RS11525	COG0714	Associated with various cellular activities
LY180_RS11530	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LY180_RS11535	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LY180_RS11540	COG4715	Zinc finger, swim domain protein
LY180_RS11545	COG4808	Protein conserved in bacteria
LY180_RS11550	COG4807	Protein conserved in bacteria
LY180_RS11555	COG3279	Response regulator of the LytR AlgR family
LY180_RS11560	COG3275	phosphorelay sensor kinase activity
LY180_RS11565	COG0789	Transcriptional regulator
LY180_RS11575	COG1174	glycine betaine transport
LY180_RS11580	COG1125	glycine betaine transport
LY180_RS11585	COG1174	glycine betaine transport
LY180_RS11590	COG1732	Glycine betaine
LY180_RS11595	COG1472	Belongs to the glycosyl hydrolase 3 family
LY180_RS11600	COG0277	FAD linked oxidase domain protein
LY180_RS11605	COG1686	Belongs to the peptidase S11 family
LY180_RS11615	COG0586	Pfam SNARE associated Golgi protein
LY180_RS11620	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS11635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LY180_RS11645	COG1346	cytolysis
LY180_RS11655	COG2949	membrane
LY180_RS11665	COG0493	'glutamate synthase
LY180_RS11670	COG0167	dihydroorotate dehydrogenase activity
LY180_RS11670	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LY180_RS11675	COG4211	Belongs to the binding-protein-dependent transport system permease family
LY180_RS11680	COG1129	ABC transporter
LY180_RS11685	COG1879	ABC-type sugar transport system periplasmic component
LY180_RS11690	COG1609	Transcriptional regulator
LY180_RS11700	COG2311	Membrane
LY180_RS11720	COG4771	TonB-dependent receptor
LY180_RS11730	COG0833	amino acid
LY180_RS11735	COG0583	DNA-binding transcription factor activity
LY180_RS11740	COG2855	membrane
LY180_RS11750	COG1522	sequence-specific DNA binding
LY180_RS11750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LY180_RS11755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LY180_RS11765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LY180_RS11770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LY180_RS11775	COG2313	pseudouridylate synthase activity
LY180_RS11780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LY180_RS11785	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LY180_RS11785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS11785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS11790	COG1105	Belongs to the carbohydrate kinase PfkB family
LY180_RS11795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS11795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS11800	COG2814	Major facilitator Superfamily
LY180_RS11815	COG0246	Mannitol dehydrogenase
LY180_RS11820	COG0523	cobalamin synthesis protein
LY180_RS11825	COG0671	phosphoesterase, PA-phosphatase related
LY180_RS11830	COG0791	NLP P60 protein
LY180_RS11835	COG2200	EAL domain
LY180_RS11840	COG4166	transmembrane transport
LY180_RS11845	COG4174	ABC transporter (Permease)
LY180_RS11850	COG4239	(ABC) transporter, permease
LY180_RS11855	COG4172	Belongs to the ABC transporter superfamily
LY180_RS11865	COG2814	Major facilitator Superfamily
LY180_RS11870	COG1187	pseudouridine synthase activity
LY180_RS11875	COG1061	Type III restriction enzyme res subunit
LY180_RS11895	COG3083	sulfuric ester hydrolase activity
LY180_RS11905	COG3468	outer membrane autotransporter barrel domain protein
LY180_RS11910	COG3468	outer membrane autotransporter barrel domain protein
LY180_RS11920	COG2197	response regulator
LY180_RS11925	COG3088	subunit of a heme lyase
LY180_RS11925	COG4235	cytochrome complex assembly
LY180_RS11930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LY180_RS11935	COG1138	Cytochrome C-type biogenesis protein
LY180_RS11945	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LY180_RS11950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LY180_RS11955	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LY180_RS11960	COG4133	protoheme IX ABC transporter activity
LY180_RS11965	COG3005	denitrification pathway
LY180_RS11970	COG3043	anaerobic respiration
LY180_RS11975	COG0348	domain, Protein
LY180_RS11980	COG0437	4 iron, 4 sulfur cluster binding
LY180_RS11990	COG3062	negative regulation of establishment of protein localization
LY180_RS11995	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS11995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS12015	COG4615	Cyclic peptide transporter
LY180_RS12020	COG3145	DNA-N1-methyladenine dioxygenase activity
LY180_RS12025	COG2169	Transcriptional regulator
LY180_RS12025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LY180_RS12030	COG1477	protein flavinylation
LY180_RS12050	COG2198	Histidine kinase
LY180_RS12050	COG0642	Histidine kinase
LY180_RS12055	COG2197	response regulator
LY180_RS12060	COG2205	protein histidine kinase activity
LY180_RS12060	COG0784	Response regulator, receiver
LY180_RS12065	COG4676	Protein conserved in bacteria
LY180_RS12070	COG5445	Predicted secreted protein (DUF2300)
LY180_RS12075	COG2373	Large extracellular alpha-helical protein
LY180_RS12080	COG3234	Protein of unknown function (DUF1175)
LY180_RS12085	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
LY180_RS12090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LY180_RS12100	COG3468	outer membrane autotransporter barrel domain protein
LY180_RS12110	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LY180_RS12115	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LY180_RS12120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LY180_RS12125	COG3642	lipopolysaccharide core region biosynthetic process
LY180_RS12135	COG0584	glycerophosphoryl diester phosphodiesterase
LY180_RS12140	COG2271	Major facilitator Superfamily
LY180_RS12145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LY180_RS12155	COG0247	lactate metabolic process
LY180_RS12160	COG5464	transposase or invertase
LY180_RS12230	COG0318	PFAM AMP-dependent synthetase and ligase
LY180_RS12240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LY180_RS12255	COG1169	isochorismate synthase
LY180_RS12260	COG4575	ribosome binding
LY180_RS12265	COG2153	protein acetylation
LY180_RS12275	COG5160	protein modification by small protein removal
LY180_RS12280	COG2234	aminopeptidase activity
LY180_RS12295	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LY180_RS12300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LY180_RS12310	COG0839	Belongs to the complex I subunit 6 family
LY180_RS12325	COG1034	ATP synthesis coupled electron transport
LY180_RS12330	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LY180_RS12335	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LY180_RS12355	COG0583	DNA-binding transcription factor activity
LY180_RS12360	COG0436	Aminotransferase
LY180_RS12370	COG0471	metal ion transport
LY180_RS12370	COG0490	domain, Protein
LY180_RS12375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LY180_RS12400	COG0857	belongs to the CobB CobQ family
LY180_RS12400	COG0280	phosphate acetyltransferase
LY180_RS12405	COG1288	antiporter activity
LY180_RS12410	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LY180_RS12415	COG0622	Phosphoesterase
LY180_RS12420	COG0625	glutathione transferase activity
LY180_RS12425	COG0625	glutathione transferase activity
LY180_RS12430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LY180_RS12435	COG1090	epimerase
LY180_RS12440	COG5464	transposase or invertase
LY180_RS12445	COG4598	ABC transporter
LY180_RS12450	COG4160	amino acid transport
LY180_RS12455	COG4215	(ABC) transporter
LY180_RS12460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LY180_RS12465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LY180_RS12470	COG0163	prenyltransferase activity
LY180_RS12475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LY180_RS12480	COG1286	toxin biosynthetic process
LY180_RS12485	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LY180_RS12490	COG0285	dihydrofolate synthase activity
LY180_RS12500	COG0586	Pfam SNARE associated Golgi protein
LY180_RS12510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LY180_RS12525	COG2814	Major facilitator Superfamily
LY180_RS12530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LY180_RS12545	COG3101	peptidyl-lysine hydroxylation
LY180_RS12550	COG0730	response to heat
LY180_RS12580	COG3539	Fimbrial protein
LY180_RS12585	COG3539	Fimbrial protein
LY180_RS12590	COG3539	Fimbrial protein
LY180_RS12595	COG3121	Chaperone
LY180_RS12600	COG3188	usher protein
LY180_RS12605	COG3539	Fimbrial protein
LY180_RS12610	COG2062	phosphohistidine phosphatase, SixA
LY180_RS12625	COG3691	Protein conserved in bacteria
LY180_RS12630	COG2067	long-chain fatty acid transport protein
LY180_RS12640	COG2853	Lipoprotein
LY180_RS12645	COG2116	formate transmembrane transporter activity
LY180_RS12680	COG2610	gluconate transmembrane transporter activity
LY180_RS12695	COG0477	Major facilitator Superfamily
LY180_RS12700	COG1566	PFAM secretion protein HlyD family protein
LY180_RS12705	COG2197	response regulator
LY180_RS12710	COG0784	Response regulator, receiver
LY180_RS12710	COG2205	protein histidine kinase activity
LY180_RS12710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LY180_RS12710	COG2198	Histidine kinase
LY180_RS12715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LY180_RS12720	COG0679	Auxin Efflux Carrier
LY180_RS12725	COG0028	Belongs to the TPP enzyme family
LY180_RS12735	COG0028	Belongs to the TPP enzyme family
LY180_RS12765	COG1560	Kdo2-lipid A biosynthetic process
LY180_RS12770	COG0436	Aminotransferase
LY180_RS12775	COG3275	phosphorelay sensor kinase activity
LY180_RS12780	COG3279	Response regulator of the LytR AlgR family
LY180_RS12785	COG2207	Transcriptional regulator
LY180_RS12795	COG1363	Peptidase, m42
LY180_RS12800	COG0006	proline dipeptidase activity
LY180_RS12805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS12810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS12840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LY180_RS12845	COG2199	diguanylate cyclase activity
LY180_RS12845	COG2200	EAL domain
LY180_RS12860	COG3415	Transposase
LY180_RS12865	COG3415	Transposase
LY180_RS12900	COG0583	DNA-binding transcription factor activity
LY180_RS12905	COG0385	Bile acid
LY180_RS12910	COG3530	Putative quorum-sensing-regulated virulence factor
LY180_RS12930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LY180_RS12935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS12940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LY180_RS12945	COG2190	(PTS) system
LY180_RS12960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LY180_RS12965	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LY180_RS12970	COG4208	sulfate ABC transporter
LY180_RS12975	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LY180_RS12980	COG4150	thiosulfate binding
LY180_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS13000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS13000	COG1263	PTS System
LY180_RS13005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LY180_RS13010	COG2837	iron assimilation
LY180_RS13030	COG0860	N-Acetylmuramoyl-L-alanine amidase
LY180_RS13040	COG2207	Transcriptional regulator
LY180_RS13045	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LY180_RS13050	COG4816	utilization protein
LY180_RS13060	COG4303	Ethanolamine ammonia lyase large subunit
LY180_RS13065	COG4819	ethanolamine utilization protein
LY180_RS13070	COG3192	ethanolamine utilization protein
LY180_RS13075	COG1454	alcohol dehydrogenase
LY180_RS13080	COG4820	ethanolamine utilization protein (EutJ)
LY180_RS13085	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS13090	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
LY180_RS13095	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LY180_RS13100	COG0280	phosphate acetyltransferase
LY180_RS13105	COG4812	Cobalamin adenosyltransferase
LY180_RS13110	COG4766	ethanolamine catabolic process
LY180_RS13115	COG4917	ethanolamine utilization protein
LY180_RS13120	COG4810	utilization protein
LY180_RS13125	COG0280	phosphate acetyltransferase
LY180_RS13125	COG0281	malic enzyme
LY180_RS13130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LY180_RS13135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LY180_RS13150	COG0493	'glutamate synthase
LY180_RS13150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS13155	COG3850	Histidine kinase
LY180_RS13160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LY180_RS13170	COG1393	Belongs to the ArsC family
LY180_RS13185	COG0400	carboxylic ester hydrolase activity
LY180_RS13190	COG1444	tRNA N-acetyltransferase activity
LY180_RS13195	COG2321	neutral zinc metallopeptidase
LY180_RS13220	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LY180_RS13230	COG2716	regulation of RNA biosynthetic process
LY180_RS13235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LY180_RS13240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS13245	COG0651	ATP synthesis coupled electron transport
LY180_RS13250	COG0650	Formate hydrogenlyase subunit 4
LY180_RS13255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LY180_RS13260	COG4237	Hydrogenase 4 membrane
LY180_RS13265	COG0651	ATP synthesis coupled electron transport
LY180_RS13270	COG3261	NADH dehydrogenase
LY180_RS13270	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LY180_RS13275	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LY180_RS13290	COG3604	Transcriptional regulator
LY180_RS13295	COG2116	formate transmembrane transporter activity
LY180_RS13300	COG0628	permease
LY180_RS13305	COG4783	chaperone-mediated protein folding
LY180_RS13310	COG1393	Belongs to the ArsC family
LY180_RS13320	COG2233	PERMEase
LY180_RS13335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LY180_RS13340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LY180_RS13345	COG0248	Ppx GppA phosphatase
LY180_RS13350	COG2200	EAL domain
LY180_RS13365	COG3133	Outer membrane lipoprotein
LY180_RS13380	COG0516	GMP reductase activity
LY180_RS13380	COG0517	IMP dehydrogenase activity
LY180_RS13390	COG1645	bacterial-type flagellum-dependent swarming motility
LY180_RS13405	COG2976	Protein conserved in bacteria
LY180_RS13435	COG4953	penicillin-binding protein 1C
LY180_RS13440	COG2373	Large extracellular alpha-helical protein
LY180_RS13445	COG2897	thiosulfate sulfurtransferase activity
LY180_RS13460	COG2975	iron-sulfur cluster assembly
LY180_RS13465	COG0633	Ferredoxin
LY180_RS13485	COG0822	iron-sulfur transferase activity
LY180_RS13505	COG0483	inositol monophosphate 1-phosphatase activity
LY180_RS13510	COG1073	alpha beta
LY180_RS13515	COG3711	transcriptional antiterminator
LY180_RS13520	COG2814	Major facilitator Superfamily
LY180_RS13525	COG0583	DNA-binding transcription factor activity
LY180_RS13535	COG4638	Rieske (2fe-2S)
LY180_RS13560	COG2259	Doxx family
LY180_RS13565	COG2017	converts alpha-aldose to the beta-anomer
LY180_RS13570	COG1063	alcohol dehydrogenase
LY180_RS13575	COG1172	Belongs to the binding-protein-dependent transport system permease family
LY180_RS13580	COG1129	ABC transporter
LY180_RS13585	COG1879	ABC-type sugar transport system periplasmic component
LY180_RS13590	COG0457	Tetratricopeptide repeat
LY180_RS13595	COG1940	carbohydrate kinase activity
LY180_RS13605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LY180_RS13605	COG1017	nitric oxide dioxygenase activity
LY180_RS13610	COG0347	Belongs to the P(II) protein family
LY180_RS13615	COG2204	response regulator
LY180_RS13620	COG3170	Tfp pilus assembly protein FimV
LY180_RS13625	COG2205	protein histidine kinase activity
LY180_RS13645	COG0560	Phosphoserine phosphatase
LY180_RS13650	COG1737	Transcriptional regulator
LY180_RS13655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS13680	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LY180_RS13700	COG0681	Belongs to the peptidase S26 family
LY180_RS13710	COG3086	response to oxidative stress
LY180_RS13715	COG3026	antisigma factor binding
LY180_RS13720	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LY180_RS13725	COG1595	DNA-templated transcription, initiation
LY180_RS13735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LY180_RS13745	COG0513	Belongs to the DEAD box helicase family
LY180_RS13750	COG0583	DNA-binding transcription factor activity
LY180_RS13770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LY180_RS13780	COG3118	belongs to the thioredoxin family
LY180_RS13785	COG3148	PFAM DTW domain containing protein
LY180_RS13790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LY180_RS13790	COG1042	CoA-binding domain protein
LY180_RS13790	COG0045	succinate-CoA ligase (ADP-forming) activity
LY180_RS13795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LY180_RS13800	COG5544	Lipoprotein
LY180_RS13805	COG0477	Major facilitator Superfamily
LY180_RS13835	COG0542	response to heat
LY180_RS13840	COG1496	oxidoreductase activity
LY180_RS13845	COG0564	pseudouridine synthase activity
LY180_RS13850	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LY180_RS13860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LY180_RS13865	COG1605	Chorismate mutase
LY180_RS13865	COG0077	Prephenate dehydratase
LY180_RS13870	COG1605	Chorismate mutase
LY180_RS13870	COG0287	Prephenate dehydrogenase
LY180_RS13875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LY180_RS13890	COG2199	diguanylate cyclase activity
LY180_RS13895	COG2885	chlorophyll binding
LY180_RS13920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LY180_RS13925	COG4137	Cytochrome C assembly protein
LY180_RS13930	COG4536	flavin adenine dinucleotide binding
LY180_RS13945	COG0497	DNA recombination
LY180_RS13950	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LY180_RS13960	COG2867	negative regulation of translational initiation
LY180_RS13970	COG0582	viral genome integration into host DNA
LY180_RS13990	COG2801	Transposase and inactivated derivatives
LY180_RS14000	COG0366	Alpha amylase catalytic
LY180_RS14010	COG0579	oxidoreductase
LY180_RS14015	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS14020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LY180_RS14025	COG1113	amino acid transport
LY180_RS14030	COG1802	Transcriptional regulator
LY180_RS14035	COG1652	LysM domain
LY180_RS14040	COG0401	homolog of Blt101
LY180_RS14045	COG0640	Transcriptional regulator
LY180_RS14050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LY180_RS14055	COG2916	Histone family protein nucleoid-structuring protein H-NS
LY180_RS14070	COG4575	ribosome binding
LY180_RS14075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LY180_RS14085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LY180_RS14090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LY180_RS14095	COG4175	Glycine betaine
LY180_RS14100	COG4176	ABC-type proline glycine betaine transport system permease component
LY180_RS14105	COG2113	Glycine betaine
LY180_RS14110	COG2814	Major facilitator Superfamily
LY180_RS14115	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LY180_RS14125	COG1846	Transcriptional regulator
LY180_RS14130	COG1566	PFAM secretion protein HlyD family protein
LY180_RS14135	COG2814	Major facilitator Superfamily
LY180_RS14160	COG1238	metal cluster binding
LY180_RS14165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LY180_RS14195	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LY180_RS14220	COG1546	Belongs to the CinA family
LY180_RS14225	COG2951	lytic endotransglycosylase activity
LY180_RS14230	COG3730	PTS system glucitol sorbitol-specific
LY180_RS14235	COG3732	PTS system glucitol sorbitol-specific
LY180_RS14245	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS14250	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS14255	COG1349	DNA-binding transcription factor activity
LY180_RS14280	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LY180_RS14295	COG1609	Transcriptional regulator
LY180_RS14300	COG1263	PTS System
LY180_RS14300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS14305	COG2723	6-phospho-beta-galactosidase activity
LY180_RS14310	COG3547	Transposase (IS116 IS110 IS902 family)
LY180_RS14320	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LY180_RS14330	COG3260	NADH ubiquinone oxidoreductase 20
LY180_RS14335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LY180_RS14340	COG3261	NADH dehydrogenase
LY180_RS14340	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LY180_RS14345	COG0650	Formate hydrogenlyase subunit 4
LY180_RS14350	COG0651	ATP synthesis coupled electron transport
LY180_RS14355	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS14370	COG0375	protein maturation
LY180_RS14375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LY180_RS14380	COG0298	carbon dioxide binding
LY180_RS14385	COG0409	Hydrogenase expression formation protein
LY180_RS14390	COG0309	Hydrogenase expression formation protein (HypE)
LY180_RS14395	COG3604	Transcriptional regulator
LY180_RS14415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LY180_RS14420	COG1349	DNA-binding transcription factor activity
LY180_RS14425	COG2084	Dehydrogenase
LY180_RS14430	COG3395	kinase activity
LY180_RS14435	COG0235	Class ii aldolase
LY180_RS14440	COG3622	Belongs to the hyi family
LY180_RS14445	COG2610	gluconate transmembrane transporter activity
LY180_RS14455	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LY180_RS14470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LY180_RS14475	COG4942	peptidase
LY180_RS14475	COG1388	LysM domain
LY180_RS14530	COG2234	aminopeptidase activity
LY180_RS14535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LY180_RS14540	COG1518	maintenance of DNA repeat elements
LY180_RS14555	COG1857	crispr-associated protein
LY180_RS14570	COG1203	CRISPR-associated helicase, Cas3
LY180_RS14595	COG0720	synthase
LY180_RS14600	COG0644	oxidoreductase
LY180_RS14605	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LY180_RS14610	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LY180_RS14615	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LY180_RS14620	COG2086	electron transfer activity
LY180_RS14625	COG0477	Major facilitator Superfamily
LY180_RS14630	COG0277	FAD linked oxidase domain protein
LY180_RS14635	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS14640	COG2223	nitrite transmembrane transporter activity
LY180_RS14645	COG1070	Carbohydrate kinase
LY180_RS14650	COG0602	queuosine metabolic process
LY180_RS14660	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LY180_RS14675	COG3956	TIGRFAM MazG family protein
LY180_RS14680	COG2337	Toxic component of a toxin-antitoxin (TA) module
LY180_RS14685	COG2336	PFAM SpoVT AbrB
LY180_RS14690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LY180_RS14705	COG4948	Mandelate Racemase Muconate Lactonizing
LY180_RS14710	COG4948	Mandelate Racemase Muconate Lactonizing
LY180_RS14715	COG2271	Major facilitator Superfamily
LY180_RS14720	COG0716	FMN binding
LY180_RS14725	COG0564	pseudouridine synthase activity
LY180_RS14730	COG3098	single-species biofilm formation
LY180_RS14750	COG1611	Belongs to the LOG family
LY180_RS14755	COG0814	amino acid
LY180_RS14760	COG1760	l-serine dehydratase
LY180_RS14770	COG1454	alcohol dehydrogenase
LY180_RS14775	COG0235	Class ii aldolase
LY180_RS14780	COG0738	Major facilitator superfamily
LY180_RS14790	COG1070	Carbohydrate kinase
LY180_RS14800	COG1349	DNA-binding transcription factor activity
LY180_RS14810	COG2363	Small membrane protein
LY180_RS14815	COG0583	DNA-binding transcription factor activity
LY180_RS14825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LY180_RS14830	COG2166	iron-sulfur cluster assembly
LY180_RS14835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LY180_RS14840	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LY180_RS14880	COG2885	chlorophyll binding
LY180_RS15025	COG0860	N-Acetylmuramoyl-L-alanine amidase
LY180_RS15030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LY180_RS15030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LY180_RS15035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LY180_RS15040	COG1074	ATP-dependent DNA helicase activity
LY180_RS15045	COG1025	Belongs to the peptidase M16 family
LY180_RS15050	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LY180_RS15055	COG4967	type IV pilus modification protein PilV
LY180_RS15065	COG4795	General secretion pathway protein
LY180_RS15070	COG2165	general secretion pathway protein
LY180_RS15085	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LY180_RS15110	COG0861	Integral membrane protein TerC family
LY180_RS15120	COG0667	Aldo Keto reductase
LY180_RS15135	COG1609	Transcriptional regulator
LY180_RS15145	COG0583	DNA-binding transcription factor activity
LY180_RS15150	COG1794	racemase activity, acting on amino acids and derivatives
LY180_RS15155	COG2814	Major facilitator Superfamily
LY180_RS15160	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS15170	COG0183	Belongs to the thiolase family
LY180_RS15175	COG0814	amino acid
LY180_RS15180	COG2771	luxR family
LY180_RS15185	COG3710	Transcriptional regulator
LY180_RS15205	COG0457	Tetratricopeptide repeat
LY180_RS15210	COG0457	Tetratricopeptide repeat
LY180_RS15210	COG3710	Transcriptional regulator
LY180_RS15225	COG2197	response regulator
LY180_RS15230	COG2197	response regulator
LY180_RS15315	COG3387	PFAM Glycoside hydrolase 15-related
LY180_RS15325	COG4942	peptidase
LY180_RS15330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LY180_RS15335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LY180_RS15340	COG2080	2 iron, 2 sulfur cluster binding
LY180_RS15345	COG3829	transcription factor binding
LY180_RS15350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LY180_RS15355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LY180_RS15360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LY180_RS15370	COG0549	Belongs to the carbamate kinase family
LY180_RS15375	COG3608	succinylglutamate desuccinylase aspartoacylase
LY180_RS15375	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LY180_RS15380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LY180_RS15385	COG2068	MobA-Related Protein
LY180_RS15390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS15390	COG0493	'glutamate synthase
LY180_RS15395	COG0402	S-adenosylhomocysteine deaminase activity
LY180_RS15400	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LY180_RS15405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LY180_RS15405	COG2080	2 iron, 2 sulfur cluster binding
LY180_RS15410	COG2233	PERMEase
LY180_RS15415	COG0402	S-adenosylhomocysteine deaminase activity
LY180_RS15420	COG2252	PERMEase
LY180_RS15425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS15430	COG0493	'glutamate synthase
LY180_RS15430	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS15440	COG2233	PERMEase
LY180_RS15465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LY180_RS15470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LY180_RS15475	COG4974	Belongs to the 'phage' integrase family
LY180_RS15480	COG0716	FMN binding
LY180_RS15490	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LY180_RS15500	COG1272	protein, Hemolysin III
LY180_RS15510	COG2723	6-phospho-beta-galactosidase activity
LY180_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS15535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LY180_RS15540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LY180_RS15545	COG0006	proline dipeptidase activity
LY180_RS15560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LY180_RS15570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LY180_RS15590	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LY180_RS15590	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LY180_RS15595	COG1703	isobutyryl-CoA mutase activity
LY180_RS15600	COG1024	Enoyl-CoA hydratase
LY180_RS15605	COG0427	acetyl-CoA hydrolase
LY180_RS15610	COG0583	DNA-binding transcription factor activity
LY180_RS15615	COG2968	Membrane
LY180_RS15620	COG1279	arginine transmembrane transporter activity
LY180_RS15625	COG0668	transmembrane transport
LY180_RS15635	COG0191	fructose-bisphosphate aldolase activity
LY180_RS15665	COG1122	ATPase activity
LY180_RS15670	COG1122	ATPase activity
LY180_RS15675	COG1072	(Pantothenic acid kinase))
LY180_RS15685	COG1494	fructose-1,6-bisphosphatase
LY180_RS15690	COG1063	alcohol dehydrogenase
LY180_RS15695	COG2213	PTS system mannitol-specific
LY180_RS15700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS15705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LY180_RS15710	COG0501	Belongs to the peptidase M48B family
LY180_RS15725	COG1662	PFAM IS1 transposase
LY180_RS15740	COG1166	arginine decarboxylase activity
LY180_RS15765	COG2814	Major facilitator Superfamily
LY180_RS15775	COG2356	endonuclease I
LY180_RS15780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LY180_RS15785	COG0189	ligase activity
LY180_RS15800	COG2805	Type II/IV secretion system protein
LY180_RS15805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LY180_RS15810	COG0762	integral membrane protein
LY180_RS15825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LY180_RS15835	COG0252	asparaginase activity
LY180_RS15850	COG3171	Protein conserved in bacteria
LY180_RS15860	COG1194	a g-specific adenine glycosylase
LY180_RS15875	COG2211	Major facilitator Superfamily
LY180_RS15880	COG1982	Orn Lys Arg decarboxylase major
LY180_RS15885	COG1811	Na channel or pump
LY180_RS15895	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LY180_RS15925	COG2165	general secretion pathway protein
LY180_RS15930	COG1459	type II secretion system
LY180_RS15935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LY180_RS15970	COG1620	l-lactate permease
LY180_RS15975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LY180_RS15980	COG3193	protein, possibly involved in utilization of glycolate and propanediol
LY180_RS15985	COG0247	lactate metabolic process
LY180_RS15990	COG0277	FAD linked oxidase domain protein
LY180_RS15995	COG0277	FAD linked oxidase domain protein
LY180_RS16000	COG2186	Transcriptional regulator
LY180_RS16005	COG0456	acetyltransferase
LY180_RS16010	COG0318	PFAM AMP-dependent synthetase and ligase
LY180_RS16020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LY180_RS16025	COG0156	8-amino-7-oxononanoate synthase activity
LY180_RS16035	COG0795	lipopolysaccharide-transporting ATPase activity
LY180_RS16040	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LY180_RS16050	COG2244	polysaccharide biosynthetic process
LY180_RS16055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LY180_RS16060	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LY180_RS16065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LY180_RS16070	COG0306	phosphate transporter
LY180_RS16075	COG0754	glutathionylspermidine amidase activity
LY180_RS16080	COG0625	glutathione transferase activity
LY180_RS16085	COG0298	carbon dioxide binding
LY180_RS16095	COG1773	rubredoxin
LY180_RS16100	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LY180_RS16105	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LY180_RS16110	COG5557	Pfam Polysulphide reductase, NrfD
LY180_RS16115	COG0437	4 iron, 4 sulfur cluster binding
LY180_RS16120	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
LY180_RS16140	COG0667	Aldo Keto reductase
LY180_RS16150	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS16155	COG0848	biopolymer transport protein
LY180_RS16160	COG0811	peptide transport
LY180_RS16170	COG0626	cystathionine gamma-synthase activity
LY180_RS16175	COG0586	Pfam SNARE associated Golgi protein
LY180_RS16180	COG2207	Transcriptional regulator
LY180_RS16190	COG1979	alcohol dehydrogenase
LY180_RS16195	COG0656	L-ascorbic acid biosynthetic process
LY180_RS16205	COG4238	major outer membrane lipoprotein
LY180_RS16210	COG1032	radical SAM domain protein
LY180_RS16215	COG2132	Multicopper oxidase
LY180_RS16220	COG0204	Acyl-transferase
LY180_RS16225	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LY180_RS16230	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LY180_RS16235	COG3111	PFAM Bacterial OB fold (BOF) protein
LY180_RS16240	COG0745	RESPONSE REGULATOR receiver
LY180_RS16245	COG0642	Histidine kinase
LY180_RS16255	COG2249	NAD(P)H dehydrogenase (quinone) activity
LY180_RS16260	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LY180_RS16265	COG0187	DNA topoisomerase II activity
LY180_RS16270	COG3150	esterase
LY180_RS16275	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LY180_RS16280	COG3151	Protein conserved in bacteria
LY180_RS16285	COG0494	nUDIX hydrolase
LY180_RS16290	COG1538	Outer membrane efflux protein
LY180_RS16305	COG0754	glutathionylspermidine amidase activity
LY180_RS16310	COG3384	dioxygenase
LY180_RS16330	COG2960	long-chain fatty acid transporting porin activity
LY180_RS16335	COG3539	Fimbrial protein
LY180_RS16340	COG3188	usher protein
LY180_RS16345	COG3121	Chaperone
LY180_RS16350	COG3539	Fimbrial protein
LY180_RS16360	COG1585	Membrane protein implicated in regulation of membrane protease activity
LY180_RS16365	COG2268	Band 7 protein
LY180_RS16390	COG3025	triphosphatase activity
LY180_RS16400	COG4991	sh3 domain protein
LY180_RS16415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LY180_RS16425	COG0583	DNA-binding transcription factor activity
LY180_RS16430	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LY180_RS16435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LY180_RS16450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LY180_RS16455	COG0358	DNA primase activity
LY180_RS16460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LY180_RS16475	COG2375	cellular response to nickel ion
LY180_RS16480	COG1695	Transcriptional regulator
LY180_RS16485	COG0840	transmembrane signaling receptor activity
LY180_RS16495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LY180_RS16500	COG1609	Transcriptional regulator
LY180_RS16505	COG3250	beta-galactosidase activity
LY180_RS16510	COG2731	YhcH YjgK YiaL family protein
LY180_RS16515	COG2731	YhcH YjgK YiaL family protein
LY180_RS16520	COG0531	amino acid
LY180_RS16530	COG3408	Glycogen debranching enzyme
LY180_RS16530	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
LY180_RS16535	COG1902	pentaerythritol trinitrate reductase activity
LY180_RS16535	COG0446	pyridine nucleotide-disulphide oxidoreductase
LY180_RS16540	COG5499	transcription regulator containing HTH domain
LY180_RS16545	COG4680	protein conserved in bacteria
LY180_RS16555	COG1451	nucleotide metabolic process
LY180_RS16560	COG2949	membrane
LY180_RS16565	COG0673	inositol 2-dehydrogenase activity
LY180_RS16570	COG0861	Integral membrane protein TerC family
LY180_RS16575	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LY180_RS16585	COG2721	sulfolactate sulfo-lyase activity
LY180_RS16595	COG2271	Major facilitator Superfamily
LY180_RS16620	COG2186	Transcriptional regulator
LY180_RS16625	COG0586	Pfam SNARE associated Golgi protein
LY180_RS16635	COG1422	Protein of unknown function (DUF1090)
LY180_RS16640	COG4575	ribosome binding
LY180_RS16645	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LY180_RS16655	COG2259	Doxx family
LY180_RS16660	COG0435	Glutathione S-transferase
LY180_RS16665	COG3152	Membrane
LY180_RS16670	COG3152	Membrane
LY180_RS16675	COG0583	DNA-binding transcription factor activity
LY180_RS16680	COG1741	Belongs to the pirin family
LY180_RS16695	COG0814	amino acid
LY180_RS16700	COG1760	l-serine dehydratase
LY180_RS16705	COG0251	oxidation-reduction process
LY180_RS16710	COG1882	Formate acetyltransferase
LY180_RS16715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LY180_RS16725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LY180_RS16730	COG0583	DNA-binding transcription factor activity
LY180_RS16750	COG1929	Belongs to the glycerate kinase type-1 family
LY180_RS16755	COG2084	Dehydrogenase
LY180_RS16765	COG2271	Major facilitator Superfamily
LY180_RS16775	COG2721	sulfolactate sulfo-lyase activity
LY180_RS16780	COG2002	toxin-antitoxin pair type II binding
LY180_RS16790	COG1349	DNA-binding transcription factor activity
LY180_RS16800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS16810	COG3716	PTS system mannose fructose sorbose family IID component
LY180_RS16815	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS16820	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LY180_RS16825	COG2222	sugar isomerase
LY180_RS16835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS16840	COG3715	PTS system
LY180_RS16845	COG3716	PTS system mannose fructose sorbose family IID component
LY180_RS16850	COG0363	glucosamine-6-phosphate deaminase activity
LY180_RS16855	COG3539	Fimbrial protein
LY180_RS16860	COG3121	Chaperone
LY180_RS16865	COG3188	usher protein
LY180_RS16870	COG3539	Fimbrial protein
LY180_RS16875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LY180_RS16895	COG2823	Periplasmic or secreted lipoprotein
LY180_RS16900	COG0701	Predicted permease
LY180_RS16905	COG0702	epimerase
LY180_RS16910	COG0693	protein deglycase activity
LY180_RS16925	COG3153	acetyltransferase
LY180_RS16930	COG3154	lipid carrier protein
LY180_RS16935	COG0826	peptidase U32
LY180_RS16940	COG0826	peptidase U32
LY180_RS16945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LY180_RS16950	COG0814	amino acid
LY180_RS16960	COG0513	Belongs to the DEAD box helicase family
LY180_RS16995	COG0195	Participates in both transcription termination and antitermination
LY180_RS17015	COG2194	sulfuric ester hydrolase activity
LY180_RS17025	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LY180_RS17035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LY180_RS17040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LY180_RS17050	COG1534	Rna-binding protein
LY180_RS17055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LY180_RS17060	COG2027	D-alanyl-D-alanine carboxypeptidase
LY180_RS17070	COG0697	spore germination
LY180_RS17085	COG0142	geranyltranstransferase activity
LY180_RS17090	COG3423	Transcriptional regulator
LY180_RS17100	COG5007	Belongs to the BolA IbaG family
LY180_RS17105	COG3113	response to antibiotic
LY180_RS17110	COG2854	intermembrane phospholipid transfer
LY180_RS17115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LY180_RS17120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LY180_RS17125	COG1127	ABC transporter
LY180_RS17130	COG0530	calcium, potassium:sodium antiporter activity
LY180_RS17135	COG0517	IMP dehydrogenase activity
LY180_RS17135	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LY180_RS17140	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LY180_RS17145	COG3117	lipopolysaccharide transmembrane transporter activity
LY180_RS17150	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LY180_RS17155	COG1137	ATPase activity
LY180_RS17160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LY180_RS17165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LY180_RS17180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS17185	COG0515	serine threonine protein kinase
LY180_RS17195	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LY180_RS17200	COG0784	Response regulator, receiver
LY180_RS17200	COG2198	Histidine kinase
LY180_RS17200	COG5002	protein histidine kinase activity
LY180_RS17205	COG1242	4 iron, 4 sulfur cluster binding
LY180_RS17210	COG0070	glutamate synthase
LY180_RS17210	COG0069	glutamate synthase activity
LY180_RS17210	COG0067	glutamate synthase
LY180_RS17215	COG0493	'glutamate synthase
LY180_RS17220	COG4804	nuclease activity
LY180_RS17225	COG2731	YhcH YjgK YiaL family protein
LY180_RS17255	COG3069	C4-dicarboxylate transmembrane transporter activity
LY180_RS17260	COG2969	positive regulation of protein catabolic process
LY180_RS17265	COG0625	glutathione transferase activity
LY180_RS17280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LY180_RS17285	COG3105	Protein conserved in bacteria
LY180_RS17290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LY180_RS17295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LY180_RS17315	COG2732	(Barnase) inhibitor
LY180_RS17335	COG0583	DNA-binding transcription factor activity
LY180_RS17340	COG0312	modulator of DNA gyrase
LY180_RS17345	COG3164	Protein of unknown function
LY180_RS17350	COG1530	ribonuclease E activity
LY180_RS17360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LY180_RS17365	COG1792	Involved in formation and maintenance of cell shape
LY180_RS17370	COG1077	Cell shape determining protein MreB Mrl
LY180_RS17380	COG2199	diguanylate cyclase activity
LY180_RS17380	COG2200	EAL domain
LY180_RS17385	COG0604	alcohol dehydrogenase
LY180_RS17405	COG0511	ligase activity, forming carbon-carbon bonds
LY180_RS17410	COG0439	Biotin carboxylase
LY180_RS17415	COG3924	membrane
LY180_RS17420	COG4145	pantothenate transmembrane transporter activity
LY180_RS17430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LY180_RS17440	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LY180_RS17450	COG1309	transcriptional regulator
LY180_RS17455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LY180_RS17460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LY180_RS17475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LY180_RS17480	COG4597	amino acid ABC transporter
LY180_RS17485	COG0765	amino acid transport
LY180_RS17490	COG1126	abc transporter atp-binding protein
LY180_RS17530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LY180_RS17550	COG0551	DNA topoisomerase type I activity
LY180_RS17560	COG0758	DNA mediated transformation
LY180_RS17580	COG0569	domain protein
LY180_RS17590	COG3036	rescue of stalled ribosome
LY180_RS17595	COG0789	Transcriptional regulator
LY180_RS17635	COG0201	protein transport
LY180_RS17725	COG0089	rRNA binding
LY180_RS17800	COG2964	Protein conserved in bacteria
LY180_RS17805	COG0545	Peptidyl-prolyl cis-trans isomerase
LY180_RS17815	COG1047	Peptidyl-prolyl cis-trans
LY180_RS17820	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LY180_RS17835	COG0488	(ABC) transporter
LY180_RS17840	COG0429	hydrolase of the alpha beta-hydrolase fold
LY180_RS17850	COG3954	Phosphoribulokinase
LY180_RS17855	COG1765	OsmC-like protein
LY180_RS17865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LY180_RS17870	COG1289	transmembrane transporter activity
LY180_RS17875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LY180_RS17880	COG0512	Glutamine amidotransferase of anthranilate synthase
LY180_RS17885	COG2184	nucleotidyltransferase activity
LY180_RS17895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LY180_RS17905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LY180_RS17910	COG2146	nitrite reductase [NAD(P)H] activity
LY180_RS17915	COG2116	formate transmembrane transporter activity
LY180_RS17930	COG0531	amino acid
LY180_RS17935	COG2222	sugar isomerase
LY180_RS17940	COG1082	Xylose isomerase domain protein TIM barrel
LY180_RS17945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LY180_RS17950	COG2188	Transcriptional regulator
LY180_RS17955	COG0626	cystathionine gamma-synthase activity
LY180_RS17970	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LY180_RS17975	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LY180_RS17980	COG3457	Alanine racemase
LY180_RS17990	COG2188	Transcriptional regulator
LY180_RS17995	COG0180	Tryptophanyl-tRNA synthetase
LY180_RS18005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LY180_RS18010	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LY180_RS18015	COG3266	domain, Protein
LY180_RS18030	COG4796	Type ii and iii secretion system protein
LY180_RS18045	COG3166	PFAM Fimbrial assembly family protein
LY180_RS18050	COG4972	Pilus assembly protein
LY180_RS18055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LY180_RS18060	COG0494	nUDIX hydrolase
LY180_RS18070	COG1011	Hydrolase
LY180_RS18075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LY180_RS18085	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LY180_RS18120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LY180_RS18125	COG2183	response to ionizing radiation
LY180_RS18130	COG1918	ferrous iron import across plasma membrane
LY180_RS18135	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LY180_RS18165	COG2610	gluconate transmembrane transporter activity
LY180_RS18170	COG1640	4-alpha-glucanotransferase
LY180_RS18175	COG0058	SHG alpha-glucan phosphorylase activity
LY180_RS18180	COG0058	SHG alpha-glucan phosphorylase activity
LY180_RS18195	COG1690	Belongs to the RtcB family
LY180_RS18200	COG4650	regulator
LY180_RS18205	COG1349	DNA-binding transcription factor activity
LY180_RS18220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LY180_RS18245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LY180_RS18250	COG0058	SHG alpha-glucan phosphorylase activity
LY180_RS18275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LY180_RS18280	COG2095	MarC family integral membrane protein
LY180_RS18285	COG2610	gluconate transmembrane transporter activity
LY180_RS18290	COG3265	gluconokinase activity
LY180_RS18295	COG1609	Transcriptional regulator
LY180_RS18300	COG1741	Belongs to the pirin family
LY180_RS18305	COG0673	inositol 2-dehydrogenase activity
LY180_RS18310	COG1247	-acetyltransferase
LY180_RS18315	COG3157	Type VI secretion system effector, Hcp
LY180_RS18330	COG0405	Gamma-glutamyltransferase
LY180_RS18340	COG0584	glycerophosphoryl diester phosphodiesterase
LY180_RS18345	COG3842	ATPase activity
LY180_RS18355	COG1175	transmembrane transport
LY180_RS18360	COG1653	transport
LY180_RS18370	COG0410	ABC transporter
LY180_RS18375	COG0411	ABC transporter
LY180_RS18380	COG4177	L-phenylalanine transmembrane transporter activity
LY180_RS18385	COG0559	Belongs to the binding-protein-dependent transport system permease family
LY180_RS18390	COG0683	leucine binding
LY180_RS18395	COG0456	acetyltransferase
LY180_RS18410	COG0683	leucine binding
LY180_RS18415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LY180_RS18420	COG2177	Part of the ABC transporter FtsEX involved in
LY180_RS18425	COG2884	Cell division ATP-binding protein ftsE
LY180_RS18430	COG0552	protein localization to endoplasmic reticulum
LY180_RS18435	COG0742	ribosomal rna small subunit methyltransferase
LY180_RS18440	COG3776	membrane
LY180_RS18450	COG3714	YhhN family
LY180_RS18465	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LY180_RS18480	COG0628	permease
LY180_RS18485	COG2091	lysine biosynthetic process via aminoadipic acid
LY180_RS18490	COG0747	negative chemotaxis
LY180_RS18495	COG0601	transmembrane transport
LY180_RS18500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LY180_RS18505	COG0444	Belongs to the ABC transporter superfamily
LY180_RS18530	COG0842	Transport permease protein
LY180_RS18535	COG1129	ABC transporter
LY180_RS18535	COG0842	Transport permease protein
LY180_RS18540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LY180_RS18570	COG2081	HI0933 family
LY180_RS18575	COG0306	phosphate transporter
LY180_RS18585	COG0589	response to stress
LY180_RS18590	COG3104	oligopeptide transport
LY180_RS18600	COG0339	signal peptide processing
LY180_RS18605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LY180_RS18610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LY180_RS18625	COG0640	Transcriptional regulator
LY180_RS18630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LY180_RS18635	COG1393	Belongs to the ArsC family
LY180_RS18655	COG3065	identical protein binding
LY180_RS18660	COG2197	response regulator
LY180_RS18665	COG1285	pathogenesis
LY180_RS18680	COG3247	response to pH
LY180_RS18685	COG2771	luxR family
LY180_RS18695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LY180_RS18700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LY180_RS18705	COG2207	Transcriptional regulator
LY180_RS18715	COG0076	glutamate decarboxylase activity
LY180_RS18720	COG1858	cytochrome C peroxidase
LY180_RS18730	COG2197	response regulator
LY180_RS18735	COG0583	DNA-binding transcription factor activity
LY180_RS18740	COG1295	ribonuclease BN
LY180_RS18745	COG0477	Major facilitator Superfamily
LY180_RS18750	COG2982	Protein involved in outer membrane biogenesis
LY180_RS18755	COG2200	EAL domain
LY180_RS18770	COG0612	Peptidase, M16
LY180_RS18780	COG2199	diguanylate cyclase activity
LY180_RS18780	COG2200	EAL domain
LY180_RS18785	COG0457	Tetratricopeptide repeat
LY180_RS18785	COG3118	belongs to the thioredoxin family
LY180_RS18790	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LY180_RS18795	COG1215	transferase activity, transferring glycosyl groups
LY180_RS18800	COG1215	transferase activity, transferring glycosyl groups
LY180_RS18825	COG2194	sulfuric ester hydrolase activity
LY180_RS18850	COG0814	amino acid
LY180_RS18855	COG4608	Belongs to the ABC transporter superfamily
LY180_RS18860	COG0444	Belongs to the ABC transporter superfamily
LY180_RS18865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LY180_RS18870	COG0601	transmembrane transport
LY180_RS18880	COG0747	negative chemotaxis
LY180_RS18900	COG2194	sulfuric ester hydrolase activity
LY180_RS18930	COG2223	nitrite transmembrane transporter activity
LY180_RS18935	COG5571	outer membrane autotransporter
LY180_RS18940	COG2818	Glycosylase
LY180_RS18945	COG0456	acetyltransferase
LY180_RS18950	COG0243	molybdopterin cofactor binding
LY180_RS18955	COG2885	chlorophyll binding
LY180_RS18970	COG2944	sequence-specific DNA binding
LY180_RS18975	COG1278	Cold shock
LY180_RS18985	COG2801	Transposase and inactivated derivatives
LY180_RS18990	COG2963	transposase activity
LY180_RS19010	COG3274	enterobacterial common antigen metabolic process
LY180_RS19020	COG4682	membrane
LY180_RS19025	COG4682	membrane
LY180_RS19030	COG1070	Carbohydrate kinase
LY180_RS19040	COG4213	ABC transporter substrate-binding protein
LY180_RS19045	COG1129	ABC transporter
LY180_RS19050	COG4214	carbohydrate transport
LY180_RS19055	COG1609	Transcriptional regulator
LY180_RS19055	COG2207	Transcriptional regulator
LY180_RS19060	COG2992	FlgJ-related protein
LY180_RS19065	COG0366	Alpha amylase catalytic
LY180_RS19070	COG3977	Valine--pyruvate aminotransferase
LY180_RS19080	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LY180_RS19085	COG1414	Transcriptional regulator
LY180_RS19095	COG2731	YhcH YjgK YiaL family protein
LY180_RS19100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LY180_RS19105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LY180_RS19110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LY180_RS19115	COG1070	Carbohydrate kinase
LY180_RS19120	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LY180_RS19125	COG3623	hexulose-6-phosphate isomerase
LY180_RS19130	COG0235	Class ii aldolase
LY180_RS19135	COG3713	MltA-interacting MipA family protein
LY180_RS19140	COG0583	DNA-binding transcription factor activity
LY180_RS19145	COG1566	PFAM secretion protein HlyD family protein
LY180_RS19160	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS19165	COG1454	alcohol dehydrogenase
LY180_RS19170	COG3276	selenocysteine insertion sequence binding
LY180_RS19180	COG0625	glutathione transferase activity
LY180_RS19185	COG3209	COG3209 Rhs family protein
LY180_RS19195	COG1413	lyase activity
LY180_RS19200	COG3209	COG3209 Rhs family protein
LY180_RS19205	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LY180_RS19215	COG1566	PFAM secretion protein HlyD family protein
LY180_RS19225	COG2213	PTS system mannitol-specific
LY180_RS19225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS19235	COG3722	fumarate hydratase activity
LY180_RS19260	COG5295	Hep Hag repeat protein
LY180_RS19265	COG1620	l-lactate permease
LY180_RS19270	COG2186	Transcriptional regulator
LY180_RS19280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LY180_RS19285	COG1045	serine acetyltransferase
LY180_RS19300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LY180_RS19305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LY180_RS19315	COG4942	peptidase
LY180_RS19320	COG2861	carbohydrate metabolic process
LY180_RS19325	COG1216	Glycosyl transferase, family 2
LY180_RS19335	COG1216	Glycosyl transferase, family 2
LY180_RS19345	COG0156	8-amino-7-oxononanoate synthase activity
LY180_RS19355	COG0859	PFAM glycosyl transferase family 9
LY180_RS19360	COG0859	PFAM glycosyl transferase family 9
LY180_RS19365	COG3307	-O-antigen
LY180_RS19370	COG1216	Glycosyl transferase, family 2
LY180_RS19375	COG1442	glycosyl transferase family 8
LY180_RS19380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LY180_RS19395	COG0515	serine threonine protein kinase
LY180_RS19400	COG0438	transferase activity, transferring glycosyl groups
LY180_RS19405	COG0859	PFAM glycosyl transferase family 9
LY180_RS19410	COG1519	Transferase
LY180_RS19440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LY180_RS19465	COG1561	YicC-like family, N-terminal region
LY180_RS19470	COG3645	SOS response
LY180_RS19475	COG2860	membrane
LY180_RS19485	COG0194	GDP metabolic process
LY180_RS19495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LY180_RS19500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LY180_RS19505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LY180_RS19515	COG0786	glutamate:sodium symporter activity
LY180_RS19520	COG2233	PERMEase
LY180_RS19525	COG2982	Protein involved in outer membrane biogenesis
LY180_RS19530	COG1501	Belongs to the glycosyl hydrolase 31 family
LY180_RS19535	COG2211	Major facilitator Superfamily
LY180_RS19545	COG0582	viral genome integration into host DNA
LY180_RS19550	COG0210	DNA helicase
LY180_RS19550	COG0210	DNA helicase
LY180_RS19555	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LY180_RS19595	COG2801	Transposase and inactivated derivatives
LY180_RS19620	COG2003	Belongs to the UPF0758 family
LY180_RS19645	COG2814	Major facilitator Superfamily
LY180_RS19650	COG0697	spore germination
LY180_RS19655	COG1464	Belongs to the NlpA lipoprotein family
LY180_RS19690	COG2252	PERMEase
LY180_RS19700	COG2271	Major facilitator Superfamily
LY180_RS19705	COG2271	Major facilitator Superfamily
LY180_RS19710	COG3851	Histidine kinase
LY180_RS19715	COG2197	response regulator
LY180_RS19720	COG0440	acetolactate synthase activity
LY180_RS19725	COG0028	Belongs to the TPP enzyme family
LY180_RS19750	COG2814	Major facilitator Superfamily
LY180_RS19755	COG0641	radical SAM
LY180_RS19765	COG2149	membrane
LY180_RS19775	COG3119	arylsulfatase activity
LY180_RS19780	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LY180_RS19785	COG2207	Transcriptional regulator
LY180_RS19800	COG2188	Transcriptional regulator
LY180_RS19825	COG5645	(Lipo)protein
LY180_RS19830	COG0823	Involved in the tonB-independent uptake of proteins
LY180_RS19840	COG2271	Major facilitator Superfamily
LY180_RS19850	COG0800	Aldolase
LY180_RS19855	COG3734	2-keto-3-deoxy-galactonokinase
LY180_RS19860	COG2186	Transcriptional regulator
LY180_RS19870	COG0561	phosphatase activity
LY180_RS19875	COG3753	Protein conserved in bacteria
LY180_RS19880	COG0187	DNA topoisomerase II activity
LY180_RS19890	COG0592	DNA-directed DNA polymerase activity
LY180_RS19935	COG0814	amino acid
LY180_RS19950	COG2091	lysine biosynthetic process via aminoadipic acid
LY180_RS19955	COG0431	NADPH-dependent FMN reductase
LY180_RS19960	COG2252	PERMEase
LY180_RS19965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LY180_RS19975	COG3196	Protein conserved in bacteria
LY180_RS19980	COG0363	glucosamine-6-phosphate deaminase activity
LY180_RS19985	COG2382	esterase
LY180_RS19995	COG2723	6-phospho-beta-galactosidase activity
LY180_RS20000	COG1263	PTS System
LY180_RS20000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS20000	COG2190	(PTS) system
LY180_RS20005	COG3711	transcriptional antiterminator
LY180_RS20010	COG0704	Plays a role in the regulation of phosphate uptake
LY180_RS20015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LY180_RS20020	COG0581	inorganic phosphate transmembrane transporter activity
LY180_RS20025	COG0573	inorganic phosphate transmembrane transporter activity
LY180_RS20030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LY180_RS20040	COG3188	usher protein
LY180_RS20055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LY180_RS20105	COG3312	ion transport
LY180_RS20120	COG0716	FMN binding
LY180_RS20125	COG1522	sequence-specific DNA binding
LY180_RS20155	COG1129	ABC transporter
LY180_RS20160	COG1172	Belongs to the binding-protein-dependent transport system permease family
LY180_RS20165	COG1609	Transcriptional regulator
LY180_RS20170	COG0477	Major facilitator Superfamily
LY180_RS20175	COG2186	Transcriptional regulator
LY180_RS20215	COG3085	chromosome segregation
LY180_RS20220	COG0606	chelatase, subunit chli
LY180_RS20235	COG3978	acetolactate synthase activity
LY180_RS20240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LY180_RS20250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LY180_RS20255	COG0583	DNA-binding transcription factor activity
LY180_RS20265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LY180_RS20270	COG3692	DNA binding
LY180_RS20275	COG0210	DNA helicase
LY180_RS20290	COG3118	belongs to the thioredoxin family
LY180_RS20300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LY180_RS20310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LY180_RS20315	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LY180_RS20320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LY180_RS20325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LY180_RS20330	COG1088	dTDP-glucose 4,6-dehydratase activity
LY180_RS20335	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LY180_RS20340	COG0456	acetyltransferase
LY180_RS20345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LY180_RS20350	COG2244	polysaccharide biosynthetic process
LY180_RS20370	COG1113	amino acid transport
LY180_RS20395	COG0641	radical SAM
LY180_RS20400	COG3119	arylsulfatase activity
LY180_RS20405	COG3071	HemY protein
LY180_RS20410	COG2959	enzyme of heme biosynthesis
LY180_RS20415	COG1587	Uroporphyrinogen-III synthase
LY180_RS20425	COG3072	Adenylate cyclase
LY180_RS20435	COG5567	small periplasmic lipoprotein
LY180_RS20445	COG3159	Protein conserved in bacteria
LY180_RS20455	COG1011	Hydrolase
LY180_RS20460	COG0210	DNA helicase
LY180_RS20465	COG3698	Phosphodiester glycosidase
LY180_RS20475	COG0598	Magnesium transport protein CorA
LY180_RS20510	COG2962	Rard protein
LY180_RS20515	COG2050	protein possibly involved in aromatic compounds catabolism
LY180_RS20520	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LY180_RS20525	COG0514	ATP-dependent DNA helicase (RecQ)
LY180_RS20530	COG1280	lysine exporter protein (LysE YggA)
LY180_RS20535	COG1280	lysine exporter protein (LysE YggA)
LY180_RS20540	COG2267	carboxylic ester hydrolase activity
LY180_RS20545	COG0561	phosphatase activity
LY180_RS20550	COG0697	spore germination
LY180_RS20555	COG0583	DNA-binding transcription factor activity
LY180_RS20565	COG0412	Dienelactone hydrolase
LY180_RS20570	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
LY180_RS20575	COG1322	Protein conserved in bacteria
LY180_RS20585	COG3165	ubiquinone biosynthetic process from chorismate
LY180_RS20595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LY180_RS20600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LY180_RS20605	COG0805	protein transport
LY180_RS20620	COG0250	Participates in transcription elongation, termination and antitermination
LY180_RS20625	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LY180_RS20630	COG0543	2 iron, 2 sulfur cluster binding
LY180_RS20650	COG1739	Uncharacterized protein family UPF0029
LY180_RS20655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LY180_RS20660	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LY180_RS20690	COG1763	Mo-molybdopterin cofactor biosynthetic process
LY180_RS20695	COG0746	molybdenum cofactor guanylyltransferase activity
LY180_RS20700	COG3084	Protein conserved in bacteria
LY180_RS20705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LY180_RS20710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LY180_RS20715	COG5339	Protein conserved in bacteria
LY180_RS20725	COG5339	Protein conserved in bacteria
LY180_RS20730	COG0204	Acyl-transferase
LY180_RS20740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LY180_RS20740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LY180_RS20755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LY180_RS20765	COG2204	response regulator
LY180_RS20770	COG3852	Histidine kinase
LY180_RS20780	COG0174	glutamine synthetase
LY180_RS20790	COG1217	gtp-binding protein TYPA
LY180_RS20795	COG2188	Transcriptional regulator
LY180_RS20800	COG1082	Xylose isomerase domain protein TIM barrel
LY180_RS20805	COG2271	Major facilitator Superfamily
LY180_RS20810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LY180_RS20815	COG2211	Major facilitator Superfamily
LY180_RS20820	COG2211	Major facilitator Superfamily
LY180_RS20825	COG1501	Belongs to the glycosyl hydrolase 31 family
LY180_RS20830	COG2017	converts alpha-aldose to the beta-anomer
LY180_RS20835	COG2942	2-epimerase
LY180_RS20840	COG3684	Belongs to the aldolase LacD family
LY180_RS20845	COG2084	Dehydrogenase
LY180_RS20850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LY180_RS20855	COG1349	DNA-binding transcription factor activity
LY180_RS20860	COG1011	Hydrolase
LY180_RS20875	COG0456	acetyltransferase
LY180_RS20885	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
LY180_RS20895	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LY180_RS20900	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LY180_RS20915	COG2864	formate dehydrogenase
LY180_RS20920	COG0437	4 iron, 4 sulfur cluster binding
LY180_RS20925	COG3383	formate dehydrogenase (NAD+) activity
LY180_RS20925	COG0243	molybdopterin cofactor binding
LY180_RS20930	COG3383	formate dehydrogenase (NAD+) activity
LY180_RS20930	COG0243	molybdopterin cofactor binding
LY180_RS20945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS20945	COG3711	transcriptional antiterminator
LY180_RS20950	COG1363	Peptidase, m42
LY180_RS20955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS20955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS20960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS21005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LY180_RS21020	COG2258	MOSC domain
LY180_RS21025	COG2205	protein histidine kinase activity
LY180_RS21030	COG0745	RESPONSE REGULATOR receiver
LY180_RS21035	COG3678	ATP-independent chaperone mediated protein folding
LY180_RS21040	COG4974	Belongs to the 'phage' integrase family
LY180_RS21115	COG4695	Portal protein
LY180_RS21205	COG5301	cellulose 1,4-beta-cellobiosidase activity
LY180_RS21265	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LY180_RS21285	COG3152	Membrane
LY180_RS21290	COG3691	Protein conserved in bacteria
LY180_RS21295	COG0589	response to stress
LY180_RS21305	COG1494	fructose-1,6-bisphosphatase
LY180_RS21315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LY180_RS21330	COG1575	Belongs to the MenA family. Type 1 subfamily
LY180_RS21345	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LY180_RS21350	COG1609	Transcriptional regulator
LY180_RS21355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LY180_RS21365	COG3209	COG3209 Rhs family protein
LY180_RS21390	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LY180_RS21395	COG3547	Transposase (IS116 IS110 IS902 family)
LY180_RS21405	COG0626	cystathionine gamma-synthase activity
LY180_RS21410	COG0527	aspartate kinase activity
LY180_RS21410	COG0460	homoserine dehydrogenase
LY180_RS21420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LY180_RS21430	COG0697	spore germination
LY180_RS21435	COG3738	Protein conserved in bacteria
LY180_RS21445	COG0371	Dehydrogenase
LY180_RS21450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LY180_RS21455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS21455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LY180_RS21455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LY180_RS21460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS21465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS21470	COG1882	Formate acetyltransferase
LY180_RS21475	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LY180_RS21480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LY180_RS21485	COG2207	Transcriptional regulator
LY180_RS21490	COG2194	sulfuric ester hydrolase activity
LY180_RS21505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LY180_RS21520	COG0583	DNA-binding transcription factor activity
LY180_RS21545	COG4206	TonB-dependent receptor
LY180_RS21580	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LY180_RS21580	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LY180_RS21620	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LY180_RS21625	COG0250	Participates in transcription elongation, termination and antitermination
LY180_RS21660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LY180_RS21670	COG2104	thiamine diphosphate biosynthetic process
LY180_RS21675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LY180_RS21710	COG3068	Protein conserved in bacteria
LY180_RS21725	COG3678	ATP-independent chaperone mediated protein folding
LY180_RS21730	COG4191	Histidine kinase
LY180_RS21735	COG2204	response regulator
LY180_RS21740	COG0151	Belongs to the GarS family
LY180_RS21760	COG3961	Belongs to the TPP enzyme family
LY180_RS21765	COG1064	alcohol dehydrogenase
LY180_RS21770	COG1454	alcohol dehydrogenase
LY180_RS21780	COG0456	acetyltransferase
LY180_RS21790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LY180_RS21795	COG2224	Isocitrate lyase
LY180_RS21810	COG1414	Transcriptional regulator
LY180_RS21815	COG0646	methionine synthase
LY180_RS21815	COG1410	methionine synthase
LY180_RS21820	COG1283	sodium-dependent phosphate transmembrane transporter activity
LY180_RS21830	COG1187	pseudouridine synthase activity
LY180_RS21845	COG3541	Predicted nucleotidyltransferase
LY180_RS21850	COG0542	response to heat
LY180_RS21855	COG0527	aspartate kinase activity
LY180_RS21880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LY180_RS21905	COG2814	Major facilitator Superfamily
LY180_RS21905	COG0477	Major facilitator Superfamily
LY180_RS21910	COG3833	ABC-type maltose transport systems, permease component
LY180_RS21915	COG1175	transmembrane transport
LY180_RS21920	COG2182	Extracellular solute-binding protein
LY180_RS21930	COG3842	ATPase activity
LY180_RS21950	COG1357	PFAM Pentapeptide repeats (8 copies)
LY180_RS21970	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LY180_RS21980	COG0534	Mate efflux family protein
LY180_RS21985	COG3237	CsbD-like
LY180_RS21990	COG0735	belongs to the Fur family
LY180_RS22000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LY180_RS22010	COG0604	alcohol dehydrogenase
LY180_RS22015	COG0305	Participates in initiation and elongation during chromosome replication
LY180_RS22020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LY180_RS22025	COG1448	Aminotransferase
LY180_RS22035	COG3700	Belongs to the class B bacterial acid phosphatase family
LY180_RS22040	COG0432	Pfam Uncharacterised protein family UPF0047
LY180_RS22045	COG2315	Protein conserved in bacteria
LY180_RS22050	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LY180_RS22055	COG0629	single-stranded DNA binding
LY180_RS22065	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LY180_RS22070	COG2207	Transcriptional regulator
LY180_RS22075	COG0789	Transcriptional regulator
LY180_RS22080	COG2252	PERMEase
LY180_RS22085	COG0025	NhaP-type Na H and K H
LY180_RS22090	COG1357	PFAM Pentapeptide repeats (8 copies)
LY180_RS22100	COG3162	membrane
LY180_RS22105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LY180_RS22115	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
LY180_RS22120	COG0437	4 iron, 4 sulfur cluster binding
LY180_RS22125	COG3301	Polysulphide reductase, NrfD
LY180_RS22130	COG1138	Cytochrome C-type biogenesis protein
LY180_RS22135	COG3088	subunit of a heme lyase
LY180_RS22140	COG4235	cytochrome complex assembly
LY180_RS22145	COG1301	dicarboxylic acid transport
LY180_RS22150	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LY180_RS22155	COG3383	formate dehydrogenase (NAD+) activity
LY180_RS22160	COG3383	formate dehydrogenase (NAD+) activity
LY180_RS22165	COG1538	Outer membrane efflux protein
LY180_RS22170	COG1289	transmembrane transporter activity
LY180_RS22175	COG1566	PFAM secretion protein HlyD family protein
LY180_RS22185	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LY180_RS22195	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LY180_RS22200	COG1940	carbohydrate kinase activity
LY180_RS22205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LY180_RS22210	COG1172	Belongs to the binding-protein-dependent transport system permease family
LY180_RS22215	COG1129	ABC transporter
LY180_RS22220	COG1879	ABC-type sugar transport system periplasmic component
LY180_RS22225	COG1737	Transcriptional regulator
LY180_RS22230	COG0698	ribose 5-phosphate isomerase
LY180_RS22240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LY180_RS22245	COG0456	acetyltransferase
LY180_RS22250	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LY180_RS22255	COG3454	Phosphonate metabolism
LY180_RS22260	COG4778	phosphonate C-P lyase system protein PhnL
LY180_RS22265	COG4107	phosphonate C-P lyase system protein PhnK
LY180_RS22270	COG3627	carbon phosphorus lyase activity
LY180_RS22275	COG3626	phosphonate metabolism
LY180_RS22280	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LY180_RS22285	COG3624	Phosphonate C-P lyase system protein PhnG
LY180_RS22290	COG2188	Transcriptional regulator
LY180_RS22300	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LY180_RS22305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LY180_RS22310	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LY180_RS22315	COG2824	Alkylphosphonate utilization operon protein PhnA
LY180_RS22320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LY180_RS22330	COG0477	Major facilitator Superfamily
LY180_RS22340	COG0642	Histidine kinase
LY180_RS22345	COG0745	RESPONSE REGULATOR receiver
LY180_RS22350	COG2194	sulfuric ester hydrolase activity
LY180_RS22355	COG0531	amino acid
LY180_RS22360	COG2207	Transcriptional regulator
LY180_RS22365	COG1982	Orn Lys Arg decarboxylase major
LY180_RS22370	COG2169	Transcriptional regulator
LY180_RS22380	COG1486	melibiose metabolic process
LY180_RS22385	COG2211	Major facilitator Superfamily
LY180_RS22390	COG3647	Membrane
LY180_RS22395	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LY180_RS22395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LY180_RS22400	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LY180_RS22410	COG4565	transcriptional regulatory protein
LY180_RS22415	COG3290	protein histidine kinase activity
LY180_RS22420	COG3592	Divergent 4Fe-4S mono-cluster
LY180_RS22425	COG2388	GCN5-related N-acetyl-transferase
LY180_RS22445	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LY180_RS22450	COG3104	oligopeptide transport
LY180_RS22455	COG1982	Orn Lys Arg decarboxylase major
LY180_RS22460	COG0531	amino acid
LY180_RS22465	COG3710	Transcriptional regulator
LY180_RS22475	COG1309	transcriptional regulator
LY180_RS22480	COG4232	protein-disulfide reductase activity
LY180_RS22490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LY180_RS22495	COG1027	Aspartate ammonia-lyase
LY180_RS22500	COG3030	protein affecting phage T7 exclusion by the F plasmid
LY180_RS22505	COG0531	amino acid
LY180_RS22530	COG1509	lysine 2,3-aminomutase activity
LY180_RS22540	COG5510	response to toxic substance
LY180_RS22545	COG5510	response to toxic substance
LY180_RS22550	COG2076	Multidrug Resistance protein
LY180_RS22555	COG3040	lipid binding
LY180_RS22560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LY180_RS22575	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LY180_RS22580	COG1053	succinate dehydrogenase
LY180_RS22590	COG0531	amino acid
LY180_RS22605	COG3264	Mechanosensitive ion channel
LY180_RS22605	COG1511	domain protein
LY180_RS22640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LY180_RS22645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LY180_RS22645	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LY180_RS22650	COG0802	atpase or kinase
LY180_RS22655	COG0860	N-Acetylmuramoyl-L-alanine amidase
LY180_RS22675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LY180_RS22680	COG0330	HflC and HflK could
LY180_RS22685	COG0330	HflC and HflK could
LY180_RS22690	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LY180_RS22705	COG0557	exoribonuclease II activity
LY180_RS22710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LY180_RS22715	COG3789	protein conserved in bacteria
LY180_RS22720	COG1842	Phage shock protein A
LY180_RS22730	COG3766	membrane
LY180_RS22735	COG5463	Belongs to the UPF0441 family
LY180_RS22740	COG0754	glutathionylspermidine amidase activity
LY180_RS22745	COG1960	acyl-CoA dehydrogenase activity
LY180_RS22755	COG3650	response to hydrogen peroxide
LY180_RS22760	COG1073	alpha beta
LY180_RS22775	COG3037	sugar-specific permease SgaT UlaA
LY180_RS22805	COG3477	response to acidic pH
LY180_RS22830	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LY180_RS22845	COG1309	transcriptional regulator
LY180_RS22855	COG0675	Transposase, IS605 OrfB family
LY180_RS22860	COG3061	Opacity-associated protein A
LY180_RS22865	COG0545	Peptidyl-prolyl cis-trans isomerase
LY180_RS22870	COG1113	amino acid transport
LY180_RS22880	COG0697	spore germination
LY180_RS22885	COG0702	epimerase
LY180_RS22890	COG1733	regulation of RNA biosynthetic process
LY180_RS22895	COG0737	Belongs to the 5'-nucleotidase family
LY180_RS22900	COG1218	3'(2'),5'-bisphosphate nucleotidase
LY180_RS22905	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LY180_RS22915	COG1253	flavin adenine dinucleotide binding
LY180_RS22930	COG0729	surface antigen
LY180_RS22935	COG2911	Protein conserved in bacteria
LY180_RS22940	COG2105	PFAM AIG2 family protein
LY180_RS22945	COG2336	PFAM SpoVT AbrB
LY180_RS22950	COG2337	Toxic component of a toxin-antitoxin (TA) module
LY180_RS22955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LY180_RS22960	COG1879	ABC-type sugar transport system periplasmic component
LY180_RS22965	COG1129	ABC transporter
LY180_RS22970	COG1172	Belongs to the binding-protein-dependent transport system permease family
LY180_RS22975	COG1172	Belongs to the binding-protein-dependent transport system permease family
LY180_RS22985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LY180_RS22995	COG0312	modulator of DNA gyrase
LY180_RS23000	COG3783	Cytochrome b(562)
LY180_RS23005	COG0602	queuosine metabolic process
LY180_RS23010	COG1328	CTP reductase activity
LY180_RS23015	COG0366	Alpha amylase catalytic
LY180_RS23020	COG1263	PTS System
LY180_RS23020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LY180_RS23025	COG1609	Transcriptional regulator
LY180_RS23030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LY180_RS23035	COG0251	oxidation-reduction process
LY180_RS23060	COG0251	oxidation-reduction process
LY180_RS23065	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS23070	COG1309	transcriptional regulator
LY180_RS23075	COG2731	YhcH YjgK YiaL family protein
LY180_RS23100	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LY180_RS23105	COG0456	acetyltransferase
LY180_RS23110	COG4269	membrane
LY180_RS23115	COG0525	valine-tRNA ligase activity
LY180_RS23120	COG2927	DNA polymerase III (CHI subunit)
LY180_RS23130	COG0795	lipopolysaccharide-transporting ATPase activity
LY180_RS23135	COG0795	lipopolysaccharide-transporting ATPase activity
LY180_RS23140	COG0433	COG0433 Predicted ATPase
LY180_RS23145	COG1609	Transcriptional regulator
LY180_RS23150	COG2610	gluconate transmembrane transporter activity
LY180_RS23155	COG1028	Short-chain dehydrogenase reductase Sdr
LY180_RS23160	COG1063	alcohol dehydrogenase
LY180_RS23165	COG3265	gluconokinase activity
LY180_RS23170	COG1064	alcohol dehydrogenase
LY180_RS23180	COG0582	viral genome integration into host DNA
LY180_RS23215	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LY180_RS23220	COG2378	regulation of single-species biofilm formation
LY180_RS23225	COG3596	GTP binding
LY180_RS23255	COG2003	Belongs to the UPF0758 family
LY180_RS23285	COG0582	viral genome integration into host DNA
LY180_RS23290	COG2815	serine threonine protein kinase
LY180_RS23290	COG0515	serine threonine protein kinase
LY180_RS23345	COG1401	restriction endodeoxyribonuclease activity
LY180_RS23365	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LY180_RS23380	COG0582	viral genome integration into host DNA
LY180_RS23385	COG4974	Belongs to the 'phage' integrase family
LY180_RS23400	COG3539	Fimbrial protein
LY180_RS23405	COG3121	Chaperone
LY180_RS23410	COG3188	usher protein
LY180_RS23415	COG3539	Fimbrial protein
LY180_RS23420	COG3539	Fimbrial protein
LY180_RS23425	COG3539	Fimbrial protein
LY180_RS23430	COG2610	gluconate transmembrane transporter activity
LY180_RS23445	COG0246	Mannitol dehydrogenase
LY180_RS23455	COG2186	Transcriptional regulator
LY180_RS23480	COG0583	DNA-binding transcription factor activity
LY180_RS23485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LY180_RS23490	COG0700	Nucleoside recognition
LY180_RS23495	COG3366	ferrous iron transmembrane transporter activity
LY180_RS23505	COG0477	Major facilitator Superfamily
LY180_RS23520	COG1924	4 iron, 4 sulfur cluster binding
LY180_RS23525	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
LY180_RS23530	COG2733	membrane
LY180_RS23535	COG2814	Major facilitator Superfamily
LY180_RS23545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LY180_RS23550	COG5457	Domain of unknown function (DUF1127)
LY180_RS23560	COG0523	cobalamin synthesis protein
LY180_RS23565	COG2879	small protein
LY180_RS23570	COG1966	Carbon starvation protein
LY180_RS23580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LY180_RS23585	COG2368	4-hydroxyphenylacetate
LY180_RS23605	COG3971	2-oxopent-4-enoate hydratase activity
LY180_RS23615	COG3384	dioxygenase
LY180_RS23620	COG1012	belongs to the aldehyde dehydrogenase family
LY180_RS23625	COG0179	Fumarylacetoacetate (FAA) hydrolase
LY180_RS23630	COG1846	Transcriptional regulator
LY180_RS23635	COG0840	transmembrane signaling receptor activity
LY180_RS23640	COG2271	Major facilitator Superfamily
LY180_RS23645	COG1802	Transcriptional regulator
LY180_RS23650	COG1063	alcohol dehydrogenase
LY180_RS23665	COG1484	DNA-dependent DNA replication
LY180_RS23680	COG2966	Psort location CytoplasmicMembrane, score
LY180_RS23685	COG2197	response regulator
LY180_RS23690	COG2197	response regulator
LY180_RS23695	COG4114	ferric iron reductase
LY180_RS23725	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LY180_RS23730	COG0456	acetyltransferase
LY180_RS23735	COG1011	Hydrolase
LY180_RS23745	COG2823	Periplasmic or secreted lipoprotein
LY180_RS23755	COG4667	esterase of the alpha-beta hydrolase superfamily
LY180_RS23760	COG0084	hydrolase, TatD family'
LY180_RS23765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LY180_RS23770	COG1328	CTP reductase activity
LY180_RS23810	COG3726	membrane protein affecting hemolysin expression
LY180_RS23815	COG0560	Phosphoserine phosphatase
LY180_RS23820	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LY180_RS23825	COG3172	ATPase kinase involved in NAD metabolism
LY180_RS23825	COG1056	cytidyltransferase-related domain
LY180_RS23835	COG0488	(ABC) transporter
LY180_RS23840	COG0741	lytic transglycosylase activity
LY180_RS23860	COG3708	Transcriptional regulator
LY180_RS23860	COG2207	Transcriptional regulator
LY180_RS23865	COG3045	CreA protein
LY180_RS23870	COG0745	RESPONSE REGULATOR receiver
LY180_RS23875	COG2205	protein histidine kinase activity
LY180_RS23880	COG4452	Inner membrane protein CreD
LY180_RS23885	COG0745	RESPONSE REGULATOR receiver