locus-tag	class	description
RG54_RS00005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RG54_RS00010	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RG54_RS00025	COG2719	SpoVR family
RG54_RS00035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RG54_RS00045	COG1619	proteins homologs of microcin C7 resistance protein MccF
RG54_RS00060	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RG54_RS00085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS00085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RG54_RS00085	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RG54_RS00090	COG1461	Dihydroxyacetone kinase
RG54_RS00095	COG2376	Dihydroxyacetone kinase
RG54_RS00100	COG3284	Transcriptional regulator
RG54_RS00120	COG0012	GTP binding
RG54_RS00135	COG0659	secondary active sulfate transmembrane transporter activity
RG54_RS00140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RG54_RS00165	COG2890	protein-(glutamine-N5) methyltransferase activity
RG54_RS00170	COG3094	Invasion gene expression up-regulator, SirB
RG54_RS00175	COG2912	Transglutaminase-like superfamily
RG54_RS00215	COG0387	Pfam Sodium calcium exchanger
RG54_RS00220	COG4572	Cation transport regulator
RG54_RS00225	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
RG54_RS00230	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
RG54_RS00235	COG4932	domain protein
RG54_RS00240	COG2197	response regulator
RG54_RS00245	COG3850	Histidine kinase
RG54_RS00255	COG2223	nitrite transmembrane transporter activity
RG54_RS00260	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RG54_RS00265	COG1140	nitrate reductase beta subunit
RG54_RS00270	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RG54_RS00275	COG2181	nitrate reductase activity
RG54_RS00295	COG0788	formyltetrahydrofolate deformylase activity
RG54_RS00305	COG1752	Esterase of the alpha-beta hydrolase superfamily
RG54_RS00310	COG0745	RESPONSE REGULATOR receiver
RG54_RS00315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RG54_RS00325	COG1435	thymidine kinase activity
RG54_RS00345	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS00345	COG1454	alcohol dehydrogenase
RG54_RS00350	COG2095	MarC family integral membrane protein
RG54_RS00360	COG4166	transmembrane transport
RG54_RS00365	COG0601	transmembrane transport
RG54_RS00370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RG54_RS00375	COG0444	Belongs to the ABC transporter superfamily
RG54_RS00380	COG4608	Belongs to the ABC transporter superfamily
RG54_RS00400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RG54_RS00405	COG2350	Protein conserved in bacteria
RG54_RS00410	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
RG54_RS00415	COG1607	acyl-coa hydrolase
RG54_RS00435	COG3047	cAMP biosynthetic process
RG54_RS00440	COG3685	Protein conserved in bacteria
RG54_RS00445	COG3685	Protein conserved in bacteria
RG54_RS00450	COG3729	General stress protein
RG54_RS00465	COG0134	indole-3-glycerol-phosphate synthase activity
RG54_RS00465	COG0135	phosphoribosylanthranilate isomerase activity
RG54_RS00470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RG54_RS00470	COG0512	Glutamine amidotransferase of anthranilate synthase
RG54_RS00475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RG54_RS00485	COG0613	PHP domain protein
RG54_RS00490	COG0009	L-threonylcarbamoyladenylate synthase
RG54_RS00495	COG1187	pseudouridine synthase activity
RG54_RS00500	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
RG54_RS00505	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS00515	COG0616	signal peptide processing
RG54_RS00525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RG54_RS00535	COG0583	DNA-binding transcription factor activity
RG54_RS00555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RG54_RS00565	COG0671	phosphoesterase, PA-phosphatase related
RG54_RS00570	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
RG54_RS00575	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
RG54_RS00585	COG0023	Translation Initiation Factor
RG54_RS00595	COG1349	DNA-binding transcription factor activity
RG54_RS00605	COG5001	Diguanylate cyclase
RG54_RS00620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RG54_RS00620	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RG54_RS00625	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RG54_RS00630	COG2852	Protein conserved in bacteria
RG54_RS00635	COG4172	Belongs to the ABC transporter superfamily
RG54_RS00640	COG4172	Belongs to the ABC transporter superfamily
RG54_RS00645	COG4171	peptide transport system, permease
RG54_RS00650	COG4168	peptide transport system, permease
RG54_RS00655	COG4166	transmembrane transport
RG54_RS00670	COG0531	amino acid
RG54_RS00675	COG0174	glutamine synthetase
RG54_RS00680	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RG54_RS00685	COG1396	sequence-specific DNA binding
RG54_RS00685	COG1917	Cupin 2, conserved barrel domain protein
RG54_RS00695	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS00700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RG54_RS00705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RG54_RS00710	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RG54_RS00715	COG1842	Phage shock protein A
RG54_RS00725	COG1983	PspC domain protein
RG54_RS00735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RG54_RS00740	COG0366	Alpha amylase catalytic
RG54_RS00745	COG1653	transport
RG54_RS00750	COG1175	transmembrane transport
RG54_RS00755	COG0395	ABC-type sugar transport system, permease component
RG54_RS00760	COG1063	alcohol dehydrogenase
RG54_RS00765	COG1082	Xylose isomerase domain protein TIM barrel
RG54_RS00770	COG0673	inositol 2-dehydrogenase activity
RG54_RS00775	COG1554	hydrolase, family 65, central catalytic
RG54_RS00780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG54_RS00785	COG3842	ATPase activity
RG54_RS00795	COG1609	Transcriptional regulator
RG54_RS00800	COG3106	COG3106 Predicted ATPase
RG54_RS00810	COG3283	Transcriptional regulator of aromatic amino acids metabolism
RG54_RS00815	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
RG54_RS00820	COG4948	Mandelate Racemase Muconate Lactonizing
RG54_RS00825	COG2866	Carboxypeptidase
RG54_RS00830	COG0702	epimerase
RG54_RS00835	COG1073	alpha beta
RG54_RS00840	COG0583	DNA-binding transcription factor activity
RG54_RS00845	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RG54_RS00850	COG4166	transmembrane transport
RG54_RS00855	COG0668	transmembrane transport
RG54_RS00860	COG3182	Iron-regulated membrane protein
RG54_RS00865	COG0589	response to stress
RG54_RS00870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RG54_RS00875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RG54_RS00880	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RG54_RS00890	COG1473	amidohydrolase
RG54_RS00895	COG1473	amidohydrolase
RG54_RS00900	COG0583	DNA-binding transcription factor activity
RG54_RS00905	COG2840	Smr protein MutS2
RG54_RS00910	COG3706	GGDEF domain
RG54_RS00925	COG0513	Belongs to the DEAD box helicase family
RG54_RS00935	COG0582	viral genome integration into host DNA
RG54_RS00955	COG3723	Recombinational DNA repair protein, rece pathway
RG54_RS00960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG54_RS01025	COG1484	DNA-dependent DNA replication
RG54_RS01030	COG1846	Transcriptional regulator
RG54_RS01045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RG54_RS01070	COG3064	Membrane
RG54_RS01085	COG3772	lysozyme
RG54_RS01095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RG54_RS01105	COG1475	DNA binding
RG54_RS01180	COG1196	nuclear chromosome segregation
RG54_RS01215	COG5301	cellulose 1,4-beta-cellobiosidase activity
RG54_RS01220	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RG54_RS01225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RG54_RS01235	COG0589	response to stress
RG54_RS01240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RG54_RS01250	COG0674	pyruvate-flavodoxin oxidoreductase activity
RG54_RS01250	COG1013	pyruvate-flavodoxin oxidoreductase activity
RG54_RS01250	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RG54_RS01250	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RG54_RS01255	COG3042	response to heat
RG54_RS01260	COG3187	Heat shock protein
RG54_RS01265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RG54_RS01270	COG2911	Protein conserved in bacteria
RG54_RS01280	COG3784	Protein of unknown function (DUF1318)
RG54_RS01285	COG2207	Transcriptional regulator
RG54_RS01290	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS01295	COG3733	amine oxidase
RG54_RS01300	COG2030	dehydratase
RG54_RS01300	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS01305	COG3396	Phenylacetate-CoA oxygenase
RG54_RS01310	COG3460	Phenylacetate-CoA oxygenase
RG54_RS01315	COG3396	Phenylacetate-CoA oxygenase
RG54_RS01320	COG2151	metal-sulfur cluster biosynthetic enzyme
RG54_RS01325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG54_RS01330	COG1024	Enoyl-CoA hydratase
RG54_RS01335	COG1024	Enoyl-CoA hydratase
RG54_RS01340	COG1250	3-hydroxyacyl-CoA dehydrogenase
RG54_RS01345	COG2050	protein possibly involved in aromatic compounds catabolism
RG54_RS01350	COG0183	Belongs to the thiolase family
RG54_RS01355	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
RG54_RS01360	COG3327	negative regulation of DNA-templated transcription, initiation
RG54_RS01365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RG54_RS01370	COG0667	Aldo Keto reductase
RG54_RS01385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RG54_RS01390	COG4589	Belongs to the CDS family
RG54_RS01395	COG2267	carboxylic ester hydrolase activity
RG54_RS01400	COG2453	phosphatase
RG54_RS01400	COG0671	phosphoesterase, PA-phosphatase related
RG54_RS01410	COG1643	Atp-dependent helicase
RG54_RS01415	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RG54_RS01420	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS01425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RG54_RS01430	COG3038	cytochrome b561
RG54_RS01445	COG0840	transmembrane signaling receptor activity
RG54_RS01450	COG0583	DNA-binding transcription factor activity
RG54_RS01455	COG5383	Protein conserved in bacteria
RG54_RS01475	COG2841	Protein conserved in bacteria
RG54_RS01480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RG54_RS01485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RG54_RS01490	COG1275	C4-dicarboxylate transporter malic acid transport protein
RG54_RS01495	COG0500	methyltransferase
RG54_RS01510	COG0675	Transposase, IS605 OrfB family
RG54_RS01515	COG3135	benzoate transporter
RG54_RS01520	COG1396	sequence-specific DNA binding
RG54_RS01525	COG0826	peptidase U32
RG54_RS01535	COG1724	mRNA binding
RG54_RS01540	COG1598	PFAM Uncharacterised protein family UPF0150
RG54_RS01545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RG54_RS01550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RG54_RS01555	COG3842	ATPase activity
RG54_RS01560	COG1176	ABC-type spermidine putrescine transport system, permease component I
RG54_RS01565	COG1177	transmembrane transport
RG54_RS01595	COG3238	Protein conserved in bacteria
RG54_RS01600	COG1247	-acetyltransferase
RG54_RS01610	COG2130	NADP-dependent
RG54_RS01615	COG1802	Transcriptional regulator
RG54_RS01620	COG4772	TonB-dependent receptor
RG54_RS01635	COG3391	amine dehydrogenase activity
RG54_RS01640	COG1113	amino acid transport
RG54_RS01670	COG3209	COG3209 Rhs family protein
RG54_RS01695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RG54_RS01700	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RG54_RS01705	COG0384	phenazine biosynthesis protein PhzF
RG54_RS01710	COG2181	nitrate reductase activity
RG54_RS01715	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RG54_RS01720	COG1140	nitrate reductase beta subunit
RG54_RS01725	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RG54_RS01730	COG2223	nitrite transmembrane transporter activity
RG54_RS01735	COG4886	Leucine-rich repeat (LRR) protein
RG54_RS01740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RG54_RS01745	COG0697	spore germination
RG54_RS01750	COG0243	molybdopterin cofactor binding
RG54_RS01750	COG3383	formate dehydrogenase (NAD+) activity
RG54_RS01755	COG3383	formate dehydrogenase (NAD+) activity
RG54_RS01755	COG0243	molybdopterin cofactor binding
RG54_RS01760	COG0437	4 iron, 4 sulfur cluster binding
RG54_RS01765	COG2864	formate dehydrogenase
RG54_RS01770	COG3093	addiction module antidote protein HigA
RG54_RS01775	COG1064	alcohol dehydrogenase
RG54_RS01800	COG1764	response to oxidative stress
RG54_RS01805	COG4608	Belongs to the ABC transporter superfamily
RG54_RS01810	COG0444	Belongs to the ABC transporter superfamily
RG54_RS01815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RG54_RS01820	COG0601	transmembrane transport
RG54_RS01830	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RG54_RS01835	COG2202	Pas domain
RG54_RS01835	COG2200	EAL domain
RG54_RS01835	COG2199	diguanylate cyclase activity
RG54_RS01845	COG1649	PFAM Uncharacterised BCR, COG1649
RG54_RS01850	COG0531	amino acid
RG54_RS01855	COG0076	glutamate decarboxylase activity
RG54_RS01870	COG0612	Peptidase, M16
RG54_RS01875	COG4771	TonB-dependent receptor
RG54_RS01880	COG4178	(ABC) transporter
RG54_RS01885	COG0641	radical SAM
RG54_RS01890	COG3119	arylsulfatase activity
RG54_RS01905	COG0243	molybdopterin cofactor binding
RG54_RS01910	COG3539	Fimbrial protein
RG54_RS01915	COG3539	Fimbrial protein
RG54_RS01920	COG3539	Fimbrial protein
RG54_RS01925	COG3188	usher protein
RG54_RS01935	COG3539	Fimbrial protein
RG54_RS01945	COG4977	sequence-specific DNA binding
RG54_RS01955	COG3550	peptidyl-serine autophosphorylation
RG54_RS01960	COG1396	sequence-specific DNA binding
RG54_RS01965	COG2911	Protein conserved in bacteria
RG54_RS01965	COG3210	domain, Protein
RG54_RS02015	COG3781	membrane
RG54_RS02035	COG2199	diguanylate cyclase activity
RG54_RS02045	COG2066	Belongs to the glutaminase family
RG54_RS02050	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS02055	COG0583	DNA-binding transcription factor activity
RG54_RS02085	COG1846	Transcriptional regulator
RG54_RS02090	COG4977	sequence-specific DNA binding
RG54_RS02100	COG2723	6-phospho-beta-galactosidase activity
RG54_RS02110	COG1447	Phosphotransferase system cellobiose-specific component IIA
RG54_RS02125	COG2188	Transcriptional regulator
RG54_RS02130	COG0697	spore germination
RG54_RS02135	COG2814	Major facilitator Superfamily
RG54_RS02145	COG3706	GGDEF domain
RG54_RS02150	COG3111	PFAM Bacterial OB fold (BOF) protein
RG54_RS02155	COG1546	Belongs to the CinA family
RG54_RS02165	COG0339	signal peptide processing
RG54_RS02175	COG4221	oxidoreductase activity
RG54_RS02180	COG1802	Transcriptional regulator
RG54_RS02190	COG0246	Mannitol dehydrogenase
RG54_RS02195	COG0477	Major facilitator Superfamily
RG54_RS02200	COG1063	alcohol dehydrogenase
RG54_RS02205	COG4948	Mandelate Racemase Muconate Lactonizing
RG54_RS02225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RG54_RS02240	COG0243	molybdopterin cofactor binding
RG54_RS02245	COG0243	molybdopterin cofactor binding
RG54_RS02250	COG0243	molybdopterin cofactor binding
RG54_RS02255	COG0437	4 iron, 4 sulfur cluster binding
RG54_RS02260	COG3302	dmso reductase anchor subunit
RG54_RS02265	COG3381	protein complex oligomerization
RG54_RS02275	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RG54_RS02280	COG1940	carbohydrate kinase activity
RG54_RS02285	COG0583	DNA-binding transcription factor activity
RG54_RS02290	COG2814	Major facilitator Superfamily
RG54_RS02310	COG3591	Belongs to the peptidase S1B family
RG54_RS02325	COG0628	permease
RG54_RS02330	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RG54_RS02335	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RG54_RS02350	COG0531	amino acid
RG54_RS02360	COG3136	membrane protein required for alginate biosynthesis
RG54_RS02365	COG0745	RESPONSE REGULATOR receiver
RG54_RS02370	COG2205	protein histidine kinase activity
RG54_RS02380	COG0114	fumarate hydratase activity
RG54_RS02385	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RG54_RS02385	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RG54_RS02390	COG1482	cell wall glycoprotein biosynthetic process
RG54_RS02395	COG5339	Protein conserved in bacteria
RG54_RS02410	COG3250	beta-galactosidase activity
RG54_RS02415	COG1309	transcriptional regulator
RG54_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS02425	COG1609	Transcriptional regulator
RG54_RS02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS02430	COG1263	PTS System
RG54_RS02435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RG54_RS02445	COG0673	inositol 2-dehydrogenase activity
RG54_RS02490	COG4659	FMN binding
RG54_RS02500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RG54_RS02510	COG3104	oligopeptide transport
RG54_RS02515	COG0625	glutathione transferase activity
RG54_RS02520	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RG54_RS02535	COG3895	Periplasmic Protein
RG54_RS02545	COG3133	Outer membrane lipoprotein
RG54_RS02560	COG1566	PFAM secretion protein HlyD family protein
RG54_RS02565	COG1289	transmembrane transporter activity
RG54_RS02570	COG2032	superoxide dismutase activity
RG54_RS02575	COG4989	oxidoreductase activity
RG54_RS02580	COG3313	Fe-S protein
RG54_RS02585	COG1309	transcriptional regulator
RG54_RS02590	COG1902	pentaerythritol trinitrate reductase activity
RG54_RS02595	COG0346	lactoylglutathione lyase activity
RG54_RS02605	COG1201	RNA secondary structure unwinding
RG54_RS02610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RG54_RS02615	COG0791	NLP P60 protein
RG54_RS02620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RG54_RS02625	COG2814	Major facilitator Superfamily
RG54_RS02645	COG0583	DNA-binding transcription factor activity
RG54_RS02650	COG2814	Major facilitator Superfamily
RG54_RS02655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RG54_RS02660	COG0307	riboflavin synthase, alpha
RG54_RS02670	COG3468	outer membrane autotransporter barrel domain protein
RG54_RS02690	COG4529	Protein conserved in bacteria
RG54_RS02700	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
RG54_RS02705	COG0437	4 iron, 4 sulfur cluster binding
RG54_RS02715	COG2414	aldehyde ferredoxin oxidoreductase
RG54_RS02720	COG0437	4 iron, 4 sulfur cluster binding
RG54_RS02730	COG0469	pyruvate kinase activity
RG54_RS02735	COG4238	major outer membrane lipoprotein
RG54_RS02740	COG1376	ErfK ybiS ycfS ynhG family protein
RG54_RS02755	COG0719	Fe-S assembly protein
RG54_RS02760	COG0396	ATPase activity
RG54_RS02765	COG0719	Fe-S assembly protein
RG54_RS02770	COG0316	Belongs to the HesB IscA family
RG54_RS02780	COG2050	protein possibly involved in aromatic compounds catabolism
RG54_RS02785	COG0277	FAD linked oxidase domain protein
RG54_RS02785	COG0247	lactate metabolic process
RG54_RS02790	COG0628	permease
RG54_RS02805	COG0738	Major facilitator superfamily
RG54_RS02810	COG2271	Major facilitator Superfamily
RG54_RS02825	COG4670	ketone body catabolic process
RG54_RS02830	COG1960	acyl-CoA dehydrogenase activity
RG54_RS02845	COG2086	electron transfer activity
RG54_RS02850	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RG54_RS02855	COG0644	oxidoreductase
RG54_RS02860	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
RG54_RS02865	COG0318	PFAM AMP-dependent synthetase and ligase
RG54_RS02870	COG0574	Belongs to the PEP-utilizing enzyme family
RG54_RS02870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RG54_RS02880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RG54_RS02885	COG4256	Hemin uptake protein
RG54_RS02895	COG2200	EAL domain
RG54_RS02900	COG0791	NLP P60 protein
RG54_RS02910	COG0386	Belongs to the glutathione peroxidase family
RG54_RS02975	COG3137	Salt-induced outer membrane protein
RG54_RS02980	COG1105	Belongs to the carbohydrate kinase PfkB family
RG54_RS02990	COG3001	Fructosamine kinase
RG54_RS03000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG54_RS03005	COG1988	membrane-bound metal-dependent
RG54_RS03010	COG1823	symporter activity
RG54_RS03025	COG0753	catalase activity
RG54_RS03035	COG1486	melibiose metabolic process
RG54_RS03040	COG2169	Transcriptional regulator
RG54_RS03040	COG1917	Cupin 2, conserved barrel domain protein
RG54_RS03045	COG1447	Phosphotransferase system cellobiose-specific component IIA
RG54_RS03050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RG54_RS03055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RG54_RS03065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG54_RS03075	COG0322	excinuclease ABC activity
RG54_RS03085	COG3678	ATP-independent chaperone mediated protein folding
RG54_RS03120	COG0708	Exodeoxyribonuclease III
RG54_RS03125	COG0398	Pfam SNARE associated Golgi protein
RG54_RS03135	COG0398	Pfam SNARE associated Golgi protein
RG54_RS03140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RG54_RS03145	COG4134	Bacterial extracellular solute-binding protein
RG54_RS03150	COG4135	transport system, permease component
RG54_RS03155	COG4136	ATPase activity
RG54_RS03160	COG2897	thiosulfate sulfurtransferase activity
RG54_RS03165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RG54_RS03170	COG0494	nUDIX hydrolase
RG54_RS03180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RG54_RS03190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RG54_RS03205	COG0778	Nitroreductase
RG54_RS03210	COG0616	signal peptide processing
RG54_RS03215	COG0252	asparaginase activity
RG54_RS03220	COG1335	isochorismatase
RG54_RS03225	COG3139	Protein of unknown function (DUF1315)
RG54_RS03235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RG54_RS03240	COG0676	glucose-6-phosphate 1-epimerase activity
RG54_RS03245	COG0656	L-ascorbic acid biosynthetic process
RG54_RS03250	COG3713	MltA-interacting MipA family protein
RG54_RS03255	COG2766	serine protein kinase
RG54_RS03265	COG2199	diguanylate cyclase activity
RG54_RS03270	COG2199	diguanylate cyclase activity
RG54_RS03275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RG54_RS03290	COG2207	Transcriptional regulator
RG54_RS03295	COG2807	transmembrane transport
RG54_RS03300	COG3344	reverse transcriptase
RG54_RS03310	COG2807	transmembrane transport
RG54_RS03315	COG3189	MarR family transcriptional regulator
RG54_RS03320	COG3042	response to heat
RG54_RS03325	COG2199	diguanylate cyclase activity
RG54_RS03325	COG2203	Gaf domain
RG54_RS03340	COG2261	transglycosylase associated protein
RG54_RS03345	COG0675	Transposase, IS605 OrfB family
RG54_RS03365	COG3615	Tellurite resistance protein tehB
RG54_RS03375	COG0583	DNA-binding transcription factor activity
RG54_RS03380	COG0473	3-isopropylmalate dehydrogenase activity
RG54_RS03385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RG54_RS03390	COG4638	Rieske (2fe-2S)
RG54_RS03395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG54_RS03400	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
RG54_RS03405	COG0318	PFAM AMP-dependent synthetase and ligase
RG54_RS03410	COG3065	identical protein binding
RG54_RS03415	COG1214	PFAM Peptidase M22, glycoprotease
RG54_RS03420	COG1199	ATP-dependent helicase activity
RG54_RS03425	COG0251	oxidation-reduction process
RG54_RS03445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RG54_RS03455	COG1760	l-serine dehydratase
RG54_RS03460	COG2200	EAL domain
RG54_RS03465	COG1253	flavin adenine dinucleotide binding
RG54_RS03480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS03480	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS03485	COG3715	PTS system
RG54_RS03490	COG3716	PTS system mannose fructose sorbose family IID component
RG54_RS03510	COG2226	methyltransferase
RG54_RS03545	COG1414	Transcriptional regulator
RG54_RS03550	COG2814	Major facilitator Superfamily
RG54_RS03560	COG0793	Belongs to the peptidase S41A family
RG54_RS03570	COG1956	GAF domain-containing protein
RG54_RS03575	COG2995	paraquat-inducible protein a
RG54_RS03580	COG3008	intermembrane lipid transfer
RG54_RS03600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RG54_RS03615	COG1276	copper resistance
RG54_RS03620	COG2372	response to copper ion
RG54_RS03630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RG54_RS03635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG54_RS03640	COG1770	oligopeptidase
RG54_RS03650	COG2979	Protein of unknown function (DUF533)
RG54_RS03670	COG3141	response to X-ray
RG54_RS03680	COG0800	Aldolase
RG54_RS03685	COG0129	dihydroxy-acid dehydratase activity
RG54_RS03690	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RG54_RS03705	COG1737	Transcriptional regulator
RG54_RS03710	COG0469	pyruvate kinase activity
RG54_RS03715	COG1560	Kdo2-lipid A biosynthetic process
RG54_RS03720	COG0739	heme binding
RG54_RS03725	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
RG54_RS03735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RG54_RS03765	COG0217	transcriptional regulatory protein
RG54_RS03770	COG0494	nUDIX hydrolase
RG54_RS03780	COG1335	isochorismatase
RG54_RS03785	COG1801	Protein of unknown function DUF72
RG54_RS03790	COG3788	relative of glutathione S-transferase, MAPEG superfamily
RG54_RS03805	COG0243	molybdopterin cofactor binding
RG54_RS03810	COG3005	denitrification pathway
RG54_RS03820	COG3102	Protein conserved in bacteria
RG54_RS03835	COG3755	Protein conserved in bacteria
RG54_RS03845	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RG54_RS03850	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RG54_RS03855	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
RG54_RS03860	COG0745	RESPONSE REGULATOR receiver
RG54_RS03865	COG2201	protein-glutamate methylesterase activity
RG54_RS03870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RG54_RS03875	COG0840	transmembrane signaling receptor activity
RG54_RS03880	COG0840	transmembrane signaling receptor activity
RG54_RS03885	COG0835	chemotaxis
RG54_RS03890	COG0643	Histidine kinase
RG54_RS03890	COG2198	Histidine kinase
RG54_RS03895	COG1360	Flagellar Motor Protein
RG54_RS03900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RG54_RS03915	COG0589	response to stress
RG54_RS03925	COG1877	trehalose-phosphatase activity
RG54_RS03930	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG54_RS03935	COG1129	ABC transporter
RG54_RS03940	COG1879	ABC-type sugar transport system periplasmic component
RG54_RS03950	COG1528	Iron-storage protein
RG54_RS03970	COG1528	Iron-storage protein
RG54_RS03980	COG0814	amino acid
RG54_RS03985	COG3012	SEC-C Motif Domain Protein
RG54_RS03985	COG3318	Belongs to the UPF0149 family
RG54_RS04015	COG2197	response regulator
RG54_RS04030	COG2197	response regulator
RG54_RS04035	COG1126	abc transporter atp-binding protein
RG54_RS04040	COG0765	amino acid transport
RG54_RS04050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG54_RS04060	COG1191	sigma factor activity
RG54_RS04075	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RG54_RS04080	COG1516	flagellar protein fliS
RG54_RS04090	COG0366	Alpha amylase catalytic
RG54_RS04105	COG2391	methyltransferase activity
RG54_RS04110	COG0425	Belongs to the sulfur carrier protein TusA family
RG54_RS04115	COG2135	peptidase activity
RG54_RS04135	COG1766	The M ring may be actively involved in energy transduction
RG54_RS04140	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RG54_RS04145	COG1317	bacterial-type flagellum organization
RG54_RS04150	COG1157	protein secretion by the type III secretion system
RG54_RS04155	COG2882	bacterial-type flagellum organization
RG54_RS04160	COG3144	bacterial-type flagellum assembly
RG54_RS04165	COG1580	Controls the rotational direction of flagella during chemotaxis
RG54_RS04170	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RG54_RS04175	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RG54_RS04180	COG3190	flagellar
RG54_RS04185	COG1338	Plays a role in the flagellum-specific transport system
RG54_RS04190	COG1987	bacterial-type flagellum assembly
RG54_RS04195	COG1684	flagellar biosynthetic protein fliR
RG54_RS04200	COG2197	response regulator
RG54_RS04225	COG3706	GGDEF domain
RG54_RS04235	COG5475	Uncharacterized small protein (DUF2158)
RG54_RS04240	COG2354	Protein conserved in bacteria
RG54_RS04245	COG0697	spore germination
RG54_RS04250	COG3727	T/G mismatch-specific endonuclease activity
RG54_RS04255	COG0270	DNA (cytosine-5-)-methyltransferase activity
RG54_RS04260	COG1418	mRNA catabolic process
RG54_RS04275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RG54_RS04290	COG2205	protein histidine kinase activity
RG54_RS04295	COG0745	RESPONSE REGULATOR receiver
RG54_RS04300	COG2351	hydroxyisourate hydrolase activity
RG54_RS04315	COG3443	Belongs to the bacterial solute-binding protein 9 family
RG54_RS04320	COG3038	cytochrome b561
RG54_RS04330	COG0727	PFAM Uncharacterised protein family (UPF0153)
RG54_RS04345	COG5301	cellulose 1,4-beta-cellobiosidase activity
RG54_RS04380	COG1196	nuclear chromosome segregation
RG54_RS04420	COG0740	serine-type endopeptidase activity
RG54_RS04455	COG3772	lysozyme
RG54_RS04480	COG3064	Membrane
RG54_RS04520	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
RG54_RS04525	COG1403	HNH endonuclease
RG54_RS04570	COG1846	Transcriptional regulator
RG54_RS04575	COG1484	DNA-dependent DNA replication
RG54_RS04645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG54_RS04675	COG1388	LysM domain
RG54_RS04675	COG1470	cell adhesion involved in biofilm formation
RG54_RS04685	COG0477	Major facilitator Superfamily
RG54_RS04690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RG54_RS04695	COG0217	transcriptional regulatory protein
RG54_RS04710	COG0534	Mate efflux family protein
RG54_RS04720	COG0583	DNA-binding transcription factor activity
RG54_RS04725	COG0583	DNA-binding transcription factor activity
RG54_RS04735	COG1376	ErfK ybiS ycfS ynhG family protein
RG54_RS04750	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
RG54_RS04775	COG1735	metal-dependent hydrolase with the TIM-barrel fold
RG54_RS04885	COG3436	PFAM IS66 Orf2 family protein
RG54_RS04890	COG4372	Transposase
RG54_RS04950	COG2003	Belongs to the UPF0758 family
RG54_RS04995	COG1289	transmembrane transporter activity
RG54_RS05005	COG1686	Belongs to the peptidase S11 family
RG54_RS05010	COG2925	Exonuclease
RG54_RS05015	COG0425	Belongs to the sulfur carrier protein TusA family
RG54_RS05020	COG2391	methyltransferase activity
RG54_RS05025	COG0531	amino acid
RG54_RS05030	COG0583	DNA-binding transcription factor activity
RG54_RS05035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RG54_RS05040	COG4115	mRNA cleavage
RG54_RS05045	COG2161	toxin-antitoxin pair type II binding
RG54_RS05075	COG0131	Imidazoleglycerol-phosphate dehydratase
RG54_RS05075	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RG54_RS05080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RG54_RS05105	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RG54_RS05110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RG54_RS05145	COG0562	UDP-galactopyranose mutase
RG54_RS05150	COG2244	polysaccharide biosynthetic process
RG54_RS05165	COG1091	dTDP-4-dehydrorhamnose reductase activity
RG54_RS05170	COG1088	dTDP-glucose 4,6-dehydratase activity
RG54_RS05180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RG54_RS05190	COG0438	transferase activity, transferring glycosyl groups
RG54_RS05195	COG2327	Polysaccharide pyruvyl transferase
RG54_RS05205	COG2244	polysaccharide biosynthetic process
RG54_RS05210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RG54_RS05215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RG54_RS05225	COG0297	glycogen (starch) synthase activity
RG54_RS05230	COG1051	belongs to the nudix hydrolase family
RG54_RS05235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RG54_RS05240	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
RG54_RS05245	COG0110	maltose O-acetyltransferase activity
RG54_RS05250	COG1216	Glycosyl transferase, family 2
RG54_RS05260	COG0438	transferase activity, transferring glycosyl groups
RG54_RS05265	COG1045	serine acetyltransferase
RG54_RS05270	COG0463	Glycosyl transferase, family 2
RG54_RS05275	COG3206	protein involved in exopolysaccharide biosynthesis
RG54_RS05275	COG0489	protein tyrosine kinase activity
RG54_RS05280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RG54_RS05285	COG1596	polysaccharide export
RG54_RS05290	COG1253	flavin adenine dinucleotide binding
RG54_RS05295	COG2982	Protein involved in outer membrane biogenesis
RG54_RS05305	COG0572	uridine kinase
RG54_RS05310	COG5002	protein histidine kinase activity
RG54_RS05310	COG3447	MASE1 domain protein
RG54_RS05310	COG5001	Diguanylate cyclase
RG54_RS05315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RG54_RS05320	COG0443	Heat shock 70 kDa protein
RG54_RS05325	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
RG54_RS05330	COG0631	protein serine/threonine phosphatase activity
RG54_RS05335	COG4245	von Willebrand factor, type A
RG54_RS05370	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RG54_RS05375	COG5301	cellulose 1,4-beta-cellobiosidase activity
RG54_RS05380	COG4220	transposase activity
RG54_RS05440	COG0582	viral genome integration into host DNA
RG54_RS05465	COG2205	protein histidine kinase activity
RG54_RS05470	COG0745	RESPONSE REGULATOR receiver
RG54_RS05485	COG3609	addiction module antidote protein, CC2985 family
RG54_RS05495	COG0826	peptidase U32
RG54_RS05520	COG1063	alcohol dehydrogenase
RG54_RS05525	COG3775	system Galactitol-specific IIC component
RG54_RS05530	COG3414	Phosphotransferase system galactitol-specific IIB component
RG54_RS05535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS05555	COG1830	Aldolase
RG54_RS05560	COG2211	Major facilitator Superfamily
RG54_RS05565	COG1397	ADP-ribosylglycohydrolase
RG54_RS05570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG54_RS05575	COG2188	Transcriptional regulator
RG54_RS05580	COG3757	hydrolase, family 25
RG54_RS05585	COG0351	phosphomethylpyrimidine kinase
RG54_RS05605	COG5455	response to cobalt ion
RG54_RS05610	COG3539	Fimbrial protein
RG54_RS05615	COG3188	usher protein
RG54_RS05620	COG3121	Chaperone
RG54_RS05625	COG3539	Fimbrial protein
RG54_RS05640	COG0489	protein tyrosine kinase activity
RG54_RS05650	COG3831	ATPase activity
RG54_RS05655	COG3831	ATPase activity
RG54_RS05675	COG0714	Associated with various cellular activities
RG54_RS05680	COG2425	protein containing a von Willebrand factor type A (vWA) domain
RG54_RS05685	COG3552	Protein containing von Willebrand factor type A (VWA) domain
RG54_RS05690	COG4715	Zinc finger, swim domain protein
RG54_RS05695	COG4808	Protein conserved in bacteria
RG54_RS05700	COG4807	Protein conserved in bacteria
RG54_RS05705	COG3279	Response regulator of the LytR AlgR family
RG54_RS05710	COG3275	phosphorelay sensor kinase activity
RG54_RS05715	COG0789	Transcriptional regulator
RG54_RS05725	COG1174	glycine betaine transport
RG54_RS05730	COG1125	glycine betaine transport
RG54_RS05735	COG1174	glycine betaine transport
RG54_RS05740	COG1732	Glycine betaine
RG54_RS05745	COG1472	Belongs to the glycosyl hydrolase 3 family
RG54_RS05750	COG0277	FAD linked oxidase domain protein
RG54_RS05755	COG1686	Belongs to the peptidase S11 family
RG54_RS05765	COG0586	Pfam SNARE associated Golgi protein
RG54_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS05795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RG54_RS05805	COG1346	cytolysis
RG54_RS05815	COG2949	membrane
RG54_RS05825	COG0493	'glutamate synthase
RG54_RS05830	COG0167	dihydroorotate dehydrogenase activity
RG54_RS05830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RG54_RS05835	COG4211	Belongs to the binding-protein-dependent transport system permease family
RG54_RS05840	COG1129	ABC transporter
RG54_RS05845	COG1879	ABC-type sugar transport system periplasmic component
RG54_RS05850	COG1609	Transcriptional regulator
RG54_RS05860	COG2311	Membrane
RG54_RS05880	COG4771	TonB-dependent receptor
RG54_RS05890	COG0833	amino acid
RG54_RS05900	COG0583	DNA-binding transcription factor activity
RG54_RS05905	COG2855	membrane
RG54_RS05915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG54_RS05915	COG1522	sequence-specific DNA binding
RG54_RS05920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RG54_RS05930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RG54_RS05935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RG54_RS05940	COG2313	pseudouridylate synthase activity
RG54_RS05945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG54_RS05955	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
RG54_RS05955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS05955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS05960	COG1105	Belongs to the carbohydrate kinase PfkB family
RG54_RS05965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS05965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS05970	COG2814	Major facilitator Superfamily
RG54_RS05985	COG0246	Mannitol dehydrogenase
RG54_RS05990	COG0523	cobalamin synthesis protein
RG54_RS05995	COG0671	phosphoesterase, PA-phosphatase related
RG54_RS06000	COG0791	NLP P60 protein
RG54_RS06005	COG2200	EAL domain
RG54_RS06010	COG4166	transmembrane transport
RG54_RS06015	COG4174	ABC transporter (Permease)
RG54_RS06020	COG4239	(ABC) transporter, permease
RG54_RS06025	COG4172	Belongs to the ABC transporter superfamily
RG54_RS06040	COG2814	Major facilitator Superfamily
RG54_RS06045	COG1187	pseudouridine synthase activity
RG54_RS06055	COG1061	Type III restriction enzyme res subunit
RG54_RS06075	COG3083	sulfuric ester hydrolase activity
RG54_RS06095	COG2197	response regulator
RG54_RS06100	COG3088	subunit of a heme lyase
RG54_RS06100	COG4235	cytochrome complex assembly
RG54_RS06105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RG54_RS06110	COG1138	Cytochrome C-type biogenesis protein
RG54_RS06120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RG54_RS06125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RG54_RS06130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RG54_RS06140	COG3005	denitrification pathway
RG54_RS06145	COG3043	anaerobic respiration
RG54_RS06150	COG0348	domain, Protein
RG54_RS06155	COG0437	4 iron, 4 sulfur cluster binding
RG54_RS06165	COG3062	negative regulation of establishment of protein localization
RG54_RS06170	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS06170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS06195	COG4615	Cyclic peptide transporter
RG54_RS06200	COG3145	DNA-N1-methyladenine dioxygenase activity
RG54_RS06205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RG54_RS06205	COG2169	Transcriptional regulator
RG54_RS06210	COG1477	protein flavinylation
RG54_RS06230	COG0642	Histidine kinase
RG54_RS06230	COG2198	Histidine kinase
RG54_RS06235	COG2197	response regulator
RG54_RS06245	COG0784	Response regulator, receiver
RG54_RS06245	COG2205	protein histidine kinase activity
RG54_RS06250	COG3852	Histidine kinase
RG54_RS06255	COG2204	response regulator
RG54_RS06260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RG54_RS06265	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RG54_RS06270	COG2031	fatty acid transporter
RG54_RS06275	COG0183	Belongs to the thiolase family
RG54_RS06280	COG4676	Protein conserved in bacteria
RG54_RS06285	COG5445	Predicted secreted protein (DUF2300)
RG54_RS06290	COG2373	Large extracellular alpha-helical protein
RG54_RS06295	COG3234	Protein of unknown function (DUF1175)
RG54_RS06300	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
RG54_RS06305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RG54_RS06315	COG3468	outer membrane autotransporter barrel domain protein
RG54_RS06325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RG54_RS06330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RG54_RS06335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG54_RS06340	COG3642	lipopolysaccharide core region biosynthetic process
RG54_RS06350	COG0583	DNA-binding transcription factor activity
RG54_RS06355	COG0584	glycerophosphoryl diester phosphodiesterase
RG54_RS06360	COG2271	Major facilitator Superfamily
RG54_RS06370	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RG54_RS06380	COG0247	lactate metabolic process
RG54_RS06385	COG5464	transposase or invertase
RG54_RS06455	COG0318	PFAM AMP-dependent synthetase and ligase
RG54_RS06465	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RG54_RS06480	COG1169	isochorismate synthase
RG54_RS06485	COG4575	ribosome binding
RG54_RS06490	COG2153	protein acetylation
RG54_RS06510	COG2304	oxidoreductase activity
RG54_RS06515	COG2234	aminopeptidase activity
RG54_RS06530	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RG54_RS06535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RG54_RS06545	COG0839	Belongs to the complex I subunit 6 family
RG54_RS06560	COG1034	ATP synthesis coupled electron transport
RG54_RS06565	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RG54_RS06570	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RG54_RS06590	COG0583	DNA-binding transcription factor activity
RG54_RS06600	COG0436	Aminotransferase
RG54_RS06610	COG0471	metal ion transport
RG54_RS06610	COG0490	domain, Protein
RG54_RS06615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG54_RS06635	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RG54_RS06640	COG0280	phosphate acetyltransferase
RG54_RS06640	COG0857	belongs to the CobB CobQ family
RG54_RS06645	COG1288	antiporter activity
RG54_RS06650	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
RG54_RS06655	COG0622	Phosphoesterase
RG54_RS06660	COG0625	glutathione transferase activity
RG54_RS06665	COG0625	glutathione transferase activity
RG54_RS06670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RG54_RS06675	COG1090	epimerase
RG54_RS06680	COG5464	transposase or invertase
RG54_RS06685	COG4598	ABC transporter
RG54_RS06690	COG4160	amino acid transport
RG54_RS06695	COG4215	(ABC) transporter
RG54_RS06700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG54_RS06705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG54_RS06710	COG0163	prenyltransferase activity
RG54_RS06715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RG54_RS06720	COG1286	toxin biosynthetic process
RG54_RS06730	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
RG54_RS06735	COG0285	dihydrofolate synthase activity
RG54_RS06745	COG0586	Pfam SNARE associated Golgi protein
RG54_RS06755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RG54_RS06770	COG2814	Major facilitator Superfamily
RG54_RS06780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RG54_RS06795	COG3101	peptidyl-lysine hydroxylation
RG54_RS06800	COG0730	response to heat
RG54_RS06815	COG2890	protein-(glutamine-N5) methyltransferase activity
RG54_RS06830	COG3539	Fimbrial protein
RG54_RS06835	COG3539	Fimbrial protein
RG54_RS06840	COG3539	Fimbrial protein
RG54_RS06845	COG3121	Chaperone
RG54_RS06850	COG3188	usher protein
RG54_RS06855	COG3539	Fimbrial protein
RG54_RS06860	COG2062	phosphohistidine phosphatase, SixA
RG54_RS06875	COG3691	Protein conserved in bacteria
RG54_RS06885	COG2067	long-chain fatty acid transport protein
RG54_RS06900	COG2853	Lipoprotein
RG54_RS06905	COG2116	formate transmembrane transporter activity
RG54_RS06915	COG0582	viral genome integration into host DNA
RG54_RS06925	COG4977	sequence-specific DNA binding
RG54_RS06935	COG1979	alcohol dehydrogenase
RG54_RS06985	COG0583	DNA-binding transcription factor activity
RG54_RS06990	COG2610	gluconate transmembrane transporter activity
RG54_RS07000	COG0477	Major facilitator Superfamily
RG54_RS07005	COG1566	PFAM secretion protein HlyD family protein
RG54_RS07010	COG2197	response regulator
RG54_RS07015	COG2205	protein histidine kinase activity
RG54_RS07015	COG2198	Histidine kinase
RG54_RS07015	COG0784	Response regulator, receiver
RG54_RS07015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG54_RS07020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RG54_RS07025	COG0679	Auxin Efflux Carrier
RG54_RS07030	COG0028	Belongs to the TPP enzyme family
RG54_RS07060	COG1560	Kdo2-lipid A biosynthetic process
RG54_RS07070	COG0436	Aminotransferase
RG54_RS07075	COG3275	phosphorelay sensor kinase activity
RG54_RS07080	COG3279	Response regulator of the LytR AlgR family
RG54_RS07085	COG2207	Transcriptional regulator
RG54_RS07095	COG1363	Peptidase, m42
RG54_RS07100	COG0006	proline dipeptidase activity
RG54_RS07105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS07110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS07140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RG54_RS07145	COG2199	diguanylate cyclase activity
RG54_RS07145	COG2200	EAL domain
RG54_RS07160	COG3415	Transposase
RG54_RS07165	COG3415	Transposase
RG54_RS07200	COG0583	DNA-binding transcription factor activity
RG54_RS07205	COG0385	Bile acid
RG54_RS07210	COG3530	Putative quorum-sensing-regulated virulence factor
RG54_RS07235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RG54_RS07240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS07245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RG54_RS07250	COG2190	(PTS) system
RG54_RS07265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RG54_RS07270	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RG54_RS07275	COG4208	sulfate ABC transporter
RG54_RS07280	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RG54_RS07285	COG4150	thiosulfate binding
RG54_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS07305	COG1263	PTS System
RG54_RS07305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS07310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RG54_RS07315	COG2837	iron assimilation
RG54_RS07335	COG0860	N-Acetylmuramoyl-L-alanine amidase
RG54_RS07345	COG2207	Transcriptional regulator
RG54_RS07350	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RG54_RS07355	COG4816	utilization protein
RG54_RS07365	COG4303	Ethanolamine ammonia lyase large subunit
RG54_RS07370	COG4819	ethanolamine utilization protein
RG54_RS07375	COG3192	ethanolamine utilization protein
RG54_RS07380	COG1454	alcohol dehydrogenase
RG54_RS07385	COG4820	ethanolamine utilization protein (EutJ)
RG54_RS07390	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS07395	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RG54_RS07400	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RG54_RS07405	COG0280	phosphate acetyltransferase
RG54_RS07410	COG4812	Cobalamin adenosyltransferase
RG54_RS07415	COG4766	ethanolamine catabolic process
RG54_RS07420	COG4917	ethanolamine utilization protein
RG54_RS07425	COG4810	utilization protein
RG54_RS07430	COG0280	phosphate acetyltransferase
RG54_RS07430	COG0281	malic enzyme
RG54_RS07435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RG54_RS07440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RG54_RS07445	COG5342	invasion associated locus B
RG54_RS07455	COG0493	'glutamate synthase
RG54_RS07455	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS07460	COG3850	Histidine kinase
RG54_RS07465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG54_RS07480	COG1393	Belongs to the ArsC family
RG54_RS07495	COG0400	carboxylic ester hydrolase activity
RG54_RS07505	COG2321	neutral zinc metallopeptidase
RG54_RS07530	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
RG54_RS07540	COG2716	regulation of RNA biosynthetic process
RG54_RS07545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RG54_RS07550	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS07555	COG0651	ATP synthesis coupled electron transport
RG54_RS07560	COG0651	ATP synthesis coupled electron transport
RG54_RS07565	COG0650	Formate hydrogenlyase subunit 4
RG54_RS07570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RG54_RS07580	COG4237	Hydrogenase 4 membrane
RG54_RS07585	COG0651	ATP synthesis coupled electron transport
RG54_RS07590	COG0651	ATP synthesis coupled electron transport
RG54_RS07595	COG3261	NADH dehydrogenase
RG54_RS07595	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
RG54_RS07600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RG54_RS07615	COG3604	Transcriptional regulator
RG54_RS07620	COG2116	formate transmembrane transporter activity
RG54_RS07625	COG2116	formate transmembrane transporter activity
RG54_RS07630	COG0628	permease
RG54_RS07635	COG4783	chaperone-mediated protein folding
RG54_RS07640	COG1393	Belongs to the ArsC family
RG54_RS07650	COG2233	PERMEase
RG54_RS07670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RG54_RS07675	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RG54_RS07680	COG0248	Ppx GppA phosphatase
RG54_RS07685	COG2200	EAL domain
RG54_RS07705	COG3133	Outer membrane lipoprotein
RG54_RS07720	COG0517	IMP dehydrogenase activity
RG54_RS07720	COG0516	GMP reductase activity
RG54_RS07730	COG1645	bacterial-type flagellum-dependent swarming motility
RG54_RS07745	COG2976	Protein conserved in bacteria
RG54_RS07775	COG4953	penicillin-binding protein 1C
RG54_RS07780	COG2373	Large extracellular alpha-helical protein
RG54_RS07785	COG2897	thiosulfate sulfurtransferase activity
RG54_RS07800	COG2975	iron-sulfur cluster assembly
RG54_RS07805	COG0633	Ferredoxin
RG54_RS07825	COG0822	iron-sulfur transferase activity
RG54_RS07845	COG0483	inositol monophosphate 1-phosphatase activity
RG54_RS07850	COG1073	alpha beta
RG54_RS07855	COG3711	transcriptional antiterminator
RG54_RS07860	COG2814	Major facilitator Superfamily
RG54_RS07865	COG0583	DNA-binding transcription factor activity
RG54_RS07870	COG4638	Rieske (2fe-2S)
RG54_RS07895	COG2259	Doxx family
RG54_RS07900	COG2017	converts alpha-aldose to the beta-anomer
RG54_RS07905	COG1063	alcohol dehydrogenase
RG54_RS07910	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG54_RS07915	COG1129	ABC transporter
RG54_RS07920	COG1879	ABC-type sugar transport system periplasmic component
RG54_RS07925	COG0457	Tetratricopeptide repeat
RG54_RS07930	COG1940	carbohydrate kinase activity
RG54_RS07945	COG1017	nitric oxide dioxygenase activity
RG54_RS07945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG54_RS07950	COG0347	Belongs to the P(II) protein family
RG54_RS07955	COG2204	response regulator
RG54_RS07960	COG3170	Tfp pilus assembly protein FimV
RG54_RS07965	COG2205	protein histidine kinase activity
RG54_RS07970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RG54_RS07970	COG0047	phosphoribosylformylglycinamidine synthase activity
RG54_RS07990	COG0560	Phosphoserine phosphatase
RG54_RS07995	COG1737	Transcriptional regulator
RG54_RS08000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS08025	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RG54_RS08050	COG0681	Belongs to the peptidase S26 family
RG54_RS08060	COG3086	response to oxidative stress
RG54_RS08065	COG3026	antisigma factor binding
RG54_RS08070	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
RG54_RS08075	COG1595	DNA-templated transcription, initiation
RG54_RS08085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RG54_RS08095	COG0513	Belongs to the DEAD box helicase family
RG54_RS08100	COG0583	DNA-binding transcription factor activity
RG54_RS08125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RG54_RS08130	COG3118	belongs to the thioredoxin family
RG54_RS08135	COG3148	PFAM DTW domain containing protein
RG54_RS08140	COG0045	succinate-CoA ligase (ADP-forming) activity
RG54_RS08140	COG1042	CoA-binding domain protein
RG54_RS08140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RG54_RS08145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RG54_RS08150	COG5544	Lipoprotein
RG54_RS08155	COG0477	Major facilitator Superfamily
RG54_RS08190	COG0542	response to heat
RG54_RS08195	COG1496	oxidoreductase activity
RG54_RS08200	COG0564	pseudouridine synthase activity
RG54_RS08205	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG54_RS08215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RG54_RS08220	COG0077	Prephenate dehydratase
RG54_RS08220	COG1605	Chorismate mutase
RG54_RS08225	COG1605	Chorismate mutase
RG54_RS08225	COG0287	Prephenate dehydrogenase
RG54_RS08230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RG54_RS08245	COG2199	diguanylate cyclase activity
RG54_RS08250	COG2885	chlorophyll binding
RG54_RS08275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RG54_RS08280	COG4137	Cytochrome C assembly protein
RG54_RS08285	COG4536	flavin adenine dinucleotide binding
RG54_RS08310	COG0497	DNA recombination
RG54_RS08315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG54_RS08325	COG2867	negative regulation of translational initiation
RG54_RS08340	COG3468	outer membrane autotransporter barrel domain protein
RG54_RS08380	COG0366	Alpha amylase catalytic
RG54_RS08385	COG0366	Alpha amylase catalytic
RG54_RS08395	COG0579	oxidoreductase
RG54_RS08400	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS08405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RG54_RS08410	COG1113	amino acid transport
RG54_RS08415	COG1802	Transcriptional regulator
RG54_RS08420	COG1652	LysM domain
RG54_RS08425	COG0401	homolog of Blt101
RG54_RS08430	COG0640	Transcriptional regulator
RG54_RS08435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RG54_RS08440	COG2916	Histone family protein nucleoid-structuring protein H-NS
RG54_RS08455	COG4575	ribosome binding
RG54_RS08460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RG54_RS08470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RG54_RS08475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RG54_RS08480	COG4175	Glycine betaine
RG54_RS08485	COG4176	ABC-type proline glycine betaine transport system permease component
RG54_RS08490	COG2113	Glycine betaine
RG54_RS08495	COG2814	Major facilitator Superfamily
RG54_RS08500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RG54_RS08510	COG1846	Transcriptional regulator
RG54_RS08515	COG1566	PFAM secretion protein HlyD family protein
RG54_RS08520	COG2814	Major facilitator Superfamily
RG54_RS08535	COG1238	metal cluster binding
RG54_RS08540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG54_RS08570	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
RG54_RS08595	COG1546	Belongs to the CinA family
RG54_RS08600	COG2951	lytic endotransglycosylase activity
RG54_RS08605	COG3730	PTS system glucitol sorbitol-specific
RG54_RS08610	COG3732	PTS system glucitol sorbitol-specific
RG54_RS08620	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS08625	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS08630	COG1349	DNA-binding transcription factor activity
RG54_RS08635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RG54_RS08635	COG0517	IMP dehydrogenase activity
RG54_RS08660	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RG54_RS08665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS08670	COG1609	Transcriptional regulator
RG54_RS08675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS08675	COG1263	PTS System
RG54_RS08680	COG2723	6-phospho-beta-galactosidase activity
RG54_RS08685	COG5499	transcription regulator containing HTH domain
RG54_RS08695	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RG54_RS08705	COG3260	NADH ubiquinone oxidoreductase 20
RG54_RS08710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RG54_RS08715	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
RG54_RS08715	COG3261	NADH dehydrogenase
RG54_RS08720	COG0650	Formate hydrogenlyase subunit 4
RG54_RS08725	COG0651	ATP synthesis coupled electron transport
RG54_RS08730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS08745	COG0375	protein maturation
RG54_RS08750	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RG54_RS08755	COG0298	carbon dioxide binding
RG54_RS08760	COG0409	Hydrogenase expression formation protein
RG54_RS08765	COG0309	Hydrogenase expression formation protein (HypE)
RG54_RS08770	COG3604	Transcriptional regulator
RG54_RS08785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RG54_RS08790	COG1349	DNA-binding transcription factor activity
RG54_RS08795	COG2084	Dehydrogenase
RG54_RS08800	COG3395	kinase activity
RG54_RS08805	COG0235	Class ii aldolase
RG54_RS08810	COG3622	Belongs to the hyi family
RG54_RS08815	COG2610	gluconate transmembrane transporter activity
RG54_RS08825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RG54_RS08840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RG54_RS08845	COG1388	LysM domain
RG54_RS08845	COG4942	peptidase
RG54_RS08900	COG2234	aminopeptidase activity
RG54_RS08905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG54_RS08910	COG1518	maintenance of DNA repeat elements
RG54_RS08925	COG1857	crispr-associated protein
RG54_RS08945	COG1203	CRISPR-associated helicase, Cas3
RG54_RS08970	COG0720	synthase
RG54_RS08975	COG0644	oxidoreductase
RG54_RS08980	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
RG54_RS08985	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RG54_RS08990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RG54_RS08995	COG2086	electron transfer activity
RG54_RS09000	COG0477	Major facilitator Superfamily
RG54_RS09005	COG0277	FAD linked oxidase domain protein
RG54_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS09015	COG2223	nitrite transmembrane transporter activity
RG54_RS09020	COG1070	Carbohydrate kinase
RG54_RS09025	COG0602	queuosine metabolic process
RG54_RS09050	COG3956	TIGRFAM MazG family protein
RG54_RS09055	COG2337	Toxic component of a toxin-antitoxin (TA) module
RG54_RS09060	COG2336	PFAM SpoVT AbrB
RG54_RS09065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RG54_RS09075	COG2205	protein histidine kinase activity
RG54_RS09075	COG4999	Histidine kinase
RG54_RS09075	COG3437	response regulator, receiver
RG54_RS09075	COG3850	Histidine kinase
RG54_RS09080	COG4948	Mandelate Racemase Muconate Lactonizing
RG54_RS09085	COG4948	Mandelate Racemase Muconate Lactonizing
RG54_RS09090	COG2271	Major facilitator Superfamily
RG54_RS09095	COG0716	FMN binding
RG54_RS09100	COG0564	pseudouridine synthase activity
RG54_RS09105	COG3098	single-species biofilm formation
RG54_RS09125	COG1611	Belongs to the LOG family
RG54_RS09130	COG0814	amino acid
RG54_RS09135	COG1760	l-serine dehydratase
RG54_RS09145	COG1454	alcohol dehydrogenase
RG54_RS09150	COG0235	Class ii aldolase
RG54_RS09155	COG0738	Major facilitator superfamily
RG54_RS09165	COG1070	Carbohydrate kinase
RG54_RS09175	COG1349	DNA-binding transcription factor activity
RG54_RS09185	COG2363	Small membrane protein
RG54_RS09190	COG0583	DNA-binding transcription factor activity
RG54_RS09200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RG54_RS09205	COG2166	iron-sulfur cluster assembly
RG54_RS09210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RG54_RS09215	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RG54_RS09250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RG54_RS09255	COG1263	PTS System
RG54_RS09255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS09260	COG3711	transcriptional antiterminator
RG54_RS09265	COG0860	N-Acetylmuramoyl-L-alanine amidase
RG54_RS09270	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RG54_RS09270	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RG54_RS09275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RG54_RS09280	COG1074	ATP-dependent DNA helicase activity
RG54_RS09285	COG1025	Belongs to the peptidase M16 family
RG54_RS09290	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
RG54_RS09295	COG4967	type IV pilus modification protein PilV
RG54_RS09305	COG4795	General secretion pathway protein
RG54_RS09310	COG2165	general secretion pathway protein
RG54_RS09325	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
RG54_RS09350	COG0861	Integral membrane protein TerC family
RG54_RS09360	COG0667	Aldo Keto reductase
RG54_RS09380	COG1609	Transcriptional regulator
RG54_RS09390	COG0583	DNA-binding transcription factor activity
RG54_RS09395	COG1794	racemase activity, acting on amino acids and derivatives
RG54_RS09400	COG2814	Major facilitator Superfamily
RG54_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS09415	COG0183	Belongs to the thiolase family
RG54_RS09420	COG0814	amino acid
RG54_RS09425	COG2771	luxR family
RG54_RS09430	COG3710	Transcriptional regulator
RG54_RS09455	COG0457	Tetratricopeptide repeat
RG54_RS09465	COG3710	Transcriptional regulator
RG54_RS09465	COG0457	Tetratricopeptide repeat
RG54_RS09475	COG0741	lytic transglycosylase activity
RG54_RS09480	COG2197	response regulator
RG54_RS09485	COG2197	response regulator
RG54_RS09560	COG3387	PFAM Glycoside hydrolase 15-related
RG54_RS09570	COG4942	peptidase
RG54_RS09580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RG54_RS09585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RG54_RS09590	COG2080	2 iron, 2 sulfur cluster binding
RG54_RS09595	COG3829	transcription factor binding
RG54_RS09600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RG54_RS09605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RG54_RS09610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RG54_RS09620	COG0549	Belongs to the carbamate kinase family
RG54_RS09625	COG3608	succinylglutamate desuccinylase aspartoacylase
RG54_RS09625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RG54_RS09630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RG54_RS09635	COG2068	MobA-Related Protein
RG54_RS09640	COG0493	'glutamate synthase
RG54_RS09640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS09645	COG0402	S-adenosylhomocysteine deaminase activity
RG54_RS09650	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RG54_RS09655	COG2080	2 iron, 2 sulfur cluster binding
RG54_RS09655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RG54_RS09660	COG2233	PERMEase
RG54_RS09665	COG0402	S-adenosylhomocysteine deaminase activity
RG54_RS09670	COG2252	PERMEase
RG54_RS09675	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS09680	COG0493	'glutamate synthase
RG54_RS09680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS09690	COG2233	PERMEase
RG54_RS09715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RG54_RS09720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RG54_RS09725	COG4974	Belongs to the 'phage' integrase family
RG54_RS09730	COG0716	FMN binding
RG54_RS09740	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
RG54_RS09750	COG1272	protein, Hemolysin III
RG54_RS09760	COG2723	6-phospho-beta-galactosidase activity
RG54_RS09765	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS09785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RG54_RS09790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RG54_RS09795	COG0006	proline dipeptidase activity
RG54_RS09820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RG54_RS09840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RG54_RS09865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RG54_RS09865	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RG54_RS09870	COG1703	isobutyryl-CoA mutase activity
RG54_RS09875	COG1024	Enoyl-CoA hydratase
RG54_RS09885	COG0583	DNA-binding transcription factor activity
RG54_RS09890	COG2968	Membrane
RG54_RS09895	COG1279	arginine transmembrane transporter activity
RG54_RS09900	COG0668	transmembrane transport
RG54_RS09905	COG0191	fructose-bisphosphate aldolase activity
RG54_RS09940	COG1122	ATPase activity
RG54_RS09945	COG1122	ATPase activity
RG54_RS09950	COG1072	(Pantothenic acid kinase))
RG54_RS09960	COG1494	fructose-1,6-bisphosphatase
RG54_RS09965	COG1063	alcohol dehydrogenase
RG54_RS09970	COG2213	PTS system mannitol-specific
RG54_RS09975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS09980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RG54_RS09985	COG0501	Belongs to the peptidase M48B family
RG54_RS10000	COG3716	PTS system mannose fructose sorbose family IID component
RG54_RS10005	COG3715	PTS system
RG54_RS10010	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS10010	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS10035	COG1166	arginine decarboxylase activity
RG54_RS10065	COG2814	Major facilitator Superfamily
RG54_RS10075	COG2356	endonuclease I
RG54_RS10080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RG54_RS10085	COG0189	ligase activity
RG54_RS10100	COG2805	Type II/IV secretion system protein
RG54_RS10105	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RG54_RS10110	COG0762	integral membrane protein
RG54_RS10125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RG54_RS10130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RG54_RS10135	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RG54_RS10150	COG0252	asparaginase activity
RG54_RS10160	COG3171	Protein conserved in bacteria
RG54_RS10175	COG1194	a g-specific adenine glycosylase
RG54_RS10190	COG2211	Major facilitator Superfamily
RG54_RS10195	COG1982	Orn Lys Arg decarboxylase major
RG54_RS10205	COG1811	Na channel or pump
RG54_RS10215	COG0582	viral genome integration into host DNA
RG54_RS10275	COG3210	domain, Protein
RG54_RS10300	COG5444	nuclease activity
RG54_RS10345	COG3210	domain, Protein
RG54_RS10350	COG2994	toxin metabolic process
RG54_RS10355	COG2831	hemolysin activation secretion protein
RG54_RS10450	COG4372	Transposase
RG54_RS10455	COG4372	Transposase
RG54_RS10470	COG3436	PFAM IS66 Orf2 family protein
RG54_RS10525	COG3468	outer membrane autotransporter barrel domain protein
RG54_RS10530	COG2020	methyltransferase activity
RG54_RS10565	COG2003	Belongs to the UPF0758 family
RG54_RS10610	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
RG54_RS10640	COG2165	general secretion pathway protein
RG54_RS10645	COG1459	type II secretion system
RG54_RS10650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RG54_RS10675	COG3064	Membrane
RG54_RS10690	COG1620	l-lactate permease
RG54_RS10695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RG54_RS10700	COG3193	protein, possibly involved in utilization of glycolate and propanediol
RG54_RS10705	COG0247	lactate metabolic process
RG54_RS10710	COG0277	FAD linked oxidase domain protein
RG54_RS10715	COG0277	FAD linked oxidase domain protein
RG54_RS10720	COG2186	Transcriptional regulator
RG54_RS10725	COG0456	acetyltransferase
RG54_RS10735	COG0318	PFAM AMP-dependent synthetase and ligase
RG54_RS10745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RG54_RS10750	COG0156	8-amino-7-oxononanoate synthase activity
RG54_RS10760	COG0795	lipopolysaccharide-transporting ATPase activity
RG54_RS10765	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
RG54_RS10775	COG2244	polysaccharide biosynthetic process
RG54_RS10780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RG54_RS10785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RG54_RS10790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RG54_RS10795	COG0306	phosphate transporter
RG54_RS10800	COG0754	glutathionylspermidine amidase activity
RG54_RS10805	COG0625	glutathione transferase activity
RG54_RS10810	COG0298	carbon dioxide binding
RG54_RS10815	COG0375	protein maturation
RG54_RS10820	COG1773	rubredoxin
RG54_RS10825	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RG54_RS10830	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
RG54_RS10835	COG5557	Pfam Polysulphide reductase, NrfD
RG54_RS10840	COG0437	4 iron, 4 sulfur cluster binding
RG54_RS10845	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RG54_RS10865	COG0667	Aldo Keto reductase
RG54_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS10880	COG0848	biopolymer transport protein
RG54_RS10885	COG0811	peptide transport
RG54_RS10895	COG0626	cystathionine gamma-synthase activity
RG54_RS10900	COG0586	Pfam SNARE associated Golgi protein
RG54_RS10905	COG2207	Transcriptional regulator
RG54_RS10915	COG1979	alcohol dehydrogenase
RG54_RS10920	COG0656	L-ascorbic acid biosynthetic process
RG54_RS10930	COG4238	major outer membrane lipoprotein
RG54_RS10935	COG1032	radical SAM domain protein
RG54_RS10940	COG2132	Multicopper oxidase
RG54_RS10945	COG0204	Acyl-transferase
RG54_RS10955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RG54_RS10965	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RG54_RS10970	COG3111	PFAM Bacterial OB fold (BOF) protein
RG54_RS10975	COG0745	RESPONSE REGULATOR receiver
RG54_RS10980	COG0642	Histidine kinase
RG54_RS10990	COG2249	NAD(P)H dehydrogenase (quinone) activity
RG54_RS10995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RG54_RS11000	COG0187	DNA topoisomerase II activity
RG54_RS11005	COG3150	esterase
RG54_RS11010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RG54_RS11015	COG3151	Protein conserved in bacteria
RG54_RS11020	COG0494	nUDIX hydrolase
RG54_RS11025	COG1538	Outer membrane efflux protein
RG54_RS11040	COG0754	glutathionylspermidine amidase activity
RG54_RS11045	COG3384	dioxygenase
RG54_RS11065	COG2960	long-chain fatty acid transporting porin activity
RG54_RS11070	COG3539	Fimbrial protein
RG54_RS11075	COG3188	usher protein
RG54_RS11080	COG3121	Chaperone
RG54_RS11085	COG3539	Fimbrial protein
RG54_RS11095	COG1585	Membrane protein implicated in regulation of membrane protease activity
RG54_RS11100	COG2268	Band 7 protein
RG54_RS11125	COG3025	triphosphatase activity
RG54_RS11135	COG4991	sh3 domain protein
RG54_RS11150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RG54_RS11160	COG0583	DNA-binding transcription factor activity
RG54_RS11170	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RG54_RS11175	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RG54_RS11190	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RG54_RS11195	COG0358	DNA primase activity
RG54_RS11205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RG54_RS11220	COG2375	cellular response to nickel ion
RG54_RS11225	COG1695	Transcriptional regulator
RG54_RS11230	COG0840	transmembrane signaling receptor activity
RG54_RS11245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RG54_RS11255	COG1609	Transcriptional regulator
RG54_RS11260	COG3250	beta-galactosidase activity
RG54_RS11265	COG2731	YhcH YjgK YiaL family protein
RG54_RS11270	COG0531	amino acid
RG54_RS11280	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
RG54_RS11280	COG3408	Glycogen debranching enzyme
RG54_RS11285	COG0446	pyridine nucleotide-disulphide oxidoreductase
RG54_RS11285	COG1902	pentaerythritol trinitrate reductase activity
RG54_RS11290	COG5499	transcription regulator containing HTH domain
RG54_RS11295	COG4680	protein conserved in bacteria
RG54_RS11305	COG1451	nucleotide metabolic process
RG54_RS11310	COG2949	membrane
RG54_RS11315	COG0673	inositol 2-dehydrogenase activity
RG54_RS11320	COG0861	Integral membrane protein TerC family
RG54_RS11325	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
RG54_RS11335	COG2721	sulfolactate sulfo-lyase activity
RG54_RS11345	COG2271	Major facilitator Superfamily
RG54_RS11370	COG2186	Transcriptional regulator
RG54_RS11375	COG0586	Pfam SNARE associated Golgi protein
RG54_RS11385	COG1422	Protein of unknown function (DUF1090)
RG54_RS11390	COG4575	ribosome binding
RG54_RS11395	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
RG54_RS11405	COG2259	Doxx family
RG54_RS11410	COG0435	Glutathione S-transferase
RG54_RS11415	COG3152	Membrane
RG54_RS11420	COG3152	Membrane
RG54_RS11430	COG0583	DNA-binding transcription factor activity
RG54_RS11435	COG1741	Belongs to the pirin family
RG54_RS11450	COG0814	amino acid
RG54_RS11455	COG1760	l-serine dehydratase
RG54_RS11460	COG0251	oxidation-reduction process
RG54_RS11465	COG1882	Formate acetyltransferase
RG54_RS11470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RG54_RS11480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RG54_RS11485	COG0583	DNA-binding transcription factor activity
RG54_RS11510	COG1929	Belongs to the glycerate kinase type-1 family
RG54_RS11515	COG2084	Dehydrogenase
RG54_RS11525	COG2271	Major facilitator Superfamily
RG54_RS11530	COG2721	sulfolactate sulfo-lyase activity
RG54_RS11535	COG2002	toxin-antitoxin pair type II binding
RG54_RS11545	COG1349	DNA-binding transcription factor activity
RG54_RS11560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS11570	COG3716	PTS system mannose fructose sorbose family IID component
RG54_RS11575	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS11580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RG54_RS11585	COG2222	sugar isomerase
RG54_RS11595	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS11605	COG3716	PTS system mannose fructose sorbose family IID component
RG54_RS11610	COG0363	glucosamine-6-phosphate deaminase activity
RG54_RS11615	COG3539	Fimbrial protein
RG54_RS11620	COG3121	Chaperone
RG54_RS11625	COG3188	usher protein
RG54_RS11630	COG3539	Fimbrial protein
RG54_RS11635	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RG54_RS11655	COG2823	Periplasmic or secreted lipoprotein
RG54_RS11660	COG0701	Predicted permease
RG54_RS11665	COG0702	epimerase
RG54_RS11670	COG0693	protein deglycase activity
RG54_RS11685	COG3153	acetyltransferase
RG54_RS11690	COG3154	lipid carrier protein
RG54_RS11695	COG0826	peptidase U32
RG54_RS11700	COG0826	peptidase U32
RG54_RS11705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RG54_RS11710	COG0814	amino acid
RG54_RS11720	COG0513	Belongs to the DEAD box helicase family
RG54_RS11760	COG0195	Participates in both transcription termination and antitermination
RG54_RS11780	COG2194	sulfuric ester hydrolase activity
RG54_RS11795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RG54_RS11805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RG54_RS11810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RG54_RS11820	COG1534	Rna-binding protein
RG54_RS11825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RG54_RS11830	COG2027	D-alanyl-D-alanine carboxypeptidase
RG54_RS11840	COG0697	spore germination
RG54_RS11855	COG0142	geranyltranstransferase activity
RG54_RS11860	COG3423	Transcriptional regulator
RG54_RS11870	COG5007	Belongs to the BolA IbaG family
RG54_RS11875	COG3113	response to antibiotic
RG54_RS11880	COG2854	intermembrane phospholipid transfer
RG54_RS11885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RG54_RS11890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RG54_RS11895	COG1127	ABC transporter
RG54_RS11900	COG0530	calcium, potassium:sodium antiporter activity
RG54_RS11905	COG0517	IMP dehydrogenase activity
RG54_RS11905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RG54_RS11910	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RG54_RS11915	COG3117	lipopolysaccharide transmembrane transporter activity
RG54_RS11920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RG54_RS11925	COG1137	ATPase activity
RG54_RS11930	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RG54_RS11935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RG54_RS11950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS11955	COG0515	serine threonine protein kinase
RG54_RS11965	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
RG54_RS11970	COG0784	Response regulator, receiver
RG54_RS11970	COG2198	Histidine kinase
RG54_RS11970	COG5002	protein histidine kinase activity
RG54_RS11975	COG1242	4 iron, 4 sulfur cluster binding
RG54_RS11985	COG0070	glutamate synthase
RG54_RS11985	COG0069	glutamate synthase activity
RG54_RS11985	COG0067	glutamate synthase
RG54_RS11990	COG0493	'glutamate synthase
RG54_RS11995	COG4804	nuclease activity
RG54_RS12000	COG2731	YhcH YjgK YiaL family protein
RG54_RS12035	COG3069	C4-dicarboxylate transmembrane transporter activity
RG54_RS12040	COG2969	positive regulation of protein catabolic process
RG54_RS12045	COG0625	glutathione transferase activity
RG54_RS12060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RG54_RS12065	COG3105	Protein conserved in bacteria
RG54_RS12070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RG54_RS12075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RG54_RS12095	COG2732	(Barnase) inhibitor
RG54_RS12115	COG0583	DNA-binding transcription factor activity
RG54_RS12120	COG0312	modulator of DNA gyrase
RG54_RS12125	COG3164	Protein of unknown function
RG54_RS12130	COG1530	ribonuclease E activity
RG54_RS12140	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RG54_RS12145	COG1792	Involved in formation and maintenance of cell shape
RG54_RS12150	COG1077	Cell shape determining protein MreB Mrl
RG54_RS12165	COG2200	EAL domain
RG54_RS12165	COG2199	diguanylate cyclase activity
RG54_RS12170	COG0604	alcohol dehydrogenase
RG54_RS12185	COG0511	ligase activity, forming carbon-carbon bonds
RG54_RS12190	COG0439	Biotin carboxylase
RG54_RS12195	COG3924	membrane
RG54_RS12200	COG4145	pantothenate transmembrane transporter activity
RG54_RS12210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RG54_RS12220	COG2189	Belongs to the N(4) N(6)-methyltransferase family
RG54_RS12230	COG1309	transcriptional regulator
RG54_RS12240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG54_RS12245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG54_RS12255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG54_RS12260	COG4597	amino acid ABC transporter
RG54_RS12265	COG0765	amino acid transport
RG54_RS12270	COG1126	abc transporter atp-binding protein
RG54_RS12310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RG54_RS12330	COG0551	DNA topoisomerase type I activity
RG54_RS12340	COG0758	DNA mediated transformation
RG54_RS12360	COG0569	domain protein
RG54_RS12370	COG3036	rescue of stalled ribosome
RG54_RS12375	COG0789	Transcriptional regulator
RG54_RS12415	COG0201	protein transport
RG54_RS12505	COG0089	rRNA binding
RG54_RS12585	COG2964	Protein conserved in bacteria
RG54_RS12590	COG0545	Peptidyl-prolyl cis-trans isomerase
RG54_RS12600	COG1047	Peptidyl-prolyl cis-trans
RG54_RS12605	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
RG54_RS12625	COG0488	(ABC) transporter
RG54_RS12630	COG0429	hydrolase of the alpha beta-hydrolase fold
RG54_RS12640	COG3954	Phosphoribulokinase
RG54_RS12645	COG1765	OsmC-like protein
RG54_RS12655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RG54_RS12660	COG1289	transmembrane transporter activity
RG54_RS12665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RG54_RS12670	COG0512	Glutamine amidotransferase of anthranilate synthase
RG54_RS12675	COG2184	nucleotidyltransferase activity
RG54_RS12685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RG54_RS12695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RG54_RS12700	COG2146	nitrite reductase [NAD(P)H] activity
RG54_RS12705	COG2116	formate transmembrane transporter activity
RG54_RS12720	COG0626	cystathionine gamma-synthase activity
RG54_RS12735	COG1735	metal-dependent hydrolase with the TIM-barrel fold
RG54_RS12740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RG54_RS12745	COG3457	Alanine racemase
RG54_RS12755	COG2188	Transcriptional regulator
RG54_RS12760	COG0180	Tryptophanyl-tRNA synthetase
RG54_RS12765	COG0546	phosphoglycolate phosphatase activity
RG54_RS12770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RG54_RS12775	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RG54_RS12780	COG3266	domain, Protein
RG54_RS12800	COG4796	Type ii and iii secretion system protein
RG54_RS12815	COG3166	PFAM Fimbrial assembly family protein
RG54_RS12820	COG4972	Pilus assembly protein
RG54_RS12825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RG54_RS12830	COG0494	nUDIX hydrolase
RG54_RS12840	COG1011	Hydrolase
RG54_RS12845	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RG54_RS12855	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RG54_RS12895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RG54_RS12900	COG2183	response to ionizing radiation
RG54_RS12910	COG1918	ferrous iron import across plasma membrane
RG54_RS12915	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RG54_RS12930	COG5464	transposase or invertase
RG54_RS12950	COG2610	gluconate transmembrane transporter activity
RG54_RS12955	COG1640	4-alpha-glucanotransferase
RG54_RS12960	COG0058	SHG alpha-glucan phosphorylase activity
RG54_RS12975	COG1690	Belongs to the RtcB family
RG54_RS12980	COG4650	regulator
RG54_RS12985	COG1349	DNA-binding transcription factor activity
RG54_RS13000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RG54_RS13020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RG54_RS13025	COG0058	SHG alpha-glucan phosphorylase activity
RG54_RS13050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RG54_RS13055	COG2095	MarC family integral membrane protein
RG54_RS13060	COG2610	gluconate transmembrane transporter activity
RG54_RS13065	COG3265	gluconokinase activity
RG54_RS13070	COG1609	Transcriptional regulator
RG54_RS13075	COG1741	Belongs to the pirin family
RG54_RS13080	COG0673	inositol 2-dehydrogenase activity
RG54_RS13085	COG1247	-acetyltransferase
RG54_RS13090	COG3157	Type VI secretion system effector, Hcp
RG54_RS13110	COG0405	Gamma-glutamyltransferase
RG54_RS13120	COG0584	glycerophosphoryl diester phosphodiesterase
RG54_RS13125	COG3842	ATPase activity
RG54_RS13135	COG1175	transmembrane transport
RG54_RS13140	COG1653	transport
RG54_RS13150	COG0410	ABC transporter
RG54_RS13155	COG0411	ABC transporter
RG54_RS13160	COG4177	L-phenylalanine transmembrane transporter activity
RG54_RS13165	COG0559	Belongs to the binding-protein-dependent transport system permease family
RG54_RS13170	COG0683	leucine binding
RG54_RS13180	COG0456	acetyltransferase
RG54_RS13185	COG0683	leucine binding
RG54_RS13190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RG54_RS13195	COG2177	Part of the ABC transporter FtsEX involved in
RG54_RS13200	COG2884	Cell division ATP-binding protein ftsE
RG54_RS13205	COG0552	protein localization to endoplasmic reticulum
RG54_RS13210	COG0742	ribosomal rna small subunit methyltransferase
RG54_RS13215	COG3776	membrane
RG54_RS13225	COG3714	YhhN family
RG54_RS13240	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RG54_RS13255	COG0628	permease
RG54_RS13260	COG2091	lysine biosynthetic process via aminoadipic acid
RG54_RS13265	COG0747	negative chemotaxis
RG54_RS13270	COG0601	transmembrane transport
RG54_RS13275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RG54_RS13280	COG0444	Belongs to the ABC transporter superfamily
RG54_RS13305	COG0842	Transport permease protein
RG54_RS13310	COG1129	ABC transporter
RG54_RS13310	COG0842	Transport permease protein
RG54_RS13315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG54_RS13345	COG2081	HI0933 family
RG54_RS13350	COG0306	phosphate transporter
RG54_RS13365	COG0589	response to stress
RG54_RS13375	COG3104	oligopeptide transport
RG54_RS13385	COG0339	signal peptide processing
RG54_RS13390	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RG54_RS13395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RG54_RS13410	COG0640	Transcriptional regulator
RG54_RS13415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RG54_RS13420	COG1393	Belongs to the ArsC family
RG54_RS13440	COG3065	identical protein binding
RG54_RS13450	COG2197	response regulator
RG54_RS13455	COG1285	pathogenesis
RG54_RS13470	COG3247	response to pH
RG54_RS13475	COG2771	luxR family
RG54_RS13485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG54_RS13490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG54_RS13500	COG2207	Transcriptional regulator
RG54_RS13510	COG0076	glutamate decarboxylase activity
RG54_RS13515	COG1858	cytochrome C peroxidase
RG54_RS13525	COG2197	response regulator
RG54_RS13530	COG0583	DNA-binding transcription factor activity
RG54_RS13535	COG1295	ribonuclease BN
RG54_RS13540	COG0477	Major facilitator Superfamily
RG54_RS13545	COG2982	Protein involved in outer membrane biogenesis
RG54_RS13550	COG2200	EAL domain
RG54_RS13565	COG0612	Peptidase, M16
RG54_RS13585	COG2199	diguanylate cyclase activity
RG54_RS13585	COG2200	EAL domain
RG54_RS13590	COG0457	Tetratricopeptide repeat
RG54_RS13590	COG3118	belongs to the thioredoxin family
RG54_RS13595	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RG54_RS13600	COG1215	transferase activity, transferring glycosyl groups
RG54_RS13605	COG1215	transferase activity, transferring glycosyl groups
RG54_RS13630	COG2194	sulfuric ester hydrolase activity
RG54_RS13670	COG0814	amino acid
RG54_RS13675	COG4608	Belongs to the ABC transporter superfamily
RG54_RS13680	COG0444	Belongs to the ABC transporter superfamily
RG54_RS13685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RG54_RS13690	COG0601	transmembrane transport
RG54_RS13695	COG0747	negative chemotaxis
RG54_RS13715	COG2194	sulfuric ester hydrolase activity
RG54_RS13745	COG2223	nitrite transmembrane transporter activity
RG54_RS13755	COG5571	outer membrane autotransporter
RG54_RS13760	COG2818	Glycosylase
RG54_RS13765	COG0456	acetyltransferase
RG54_RS13770	COG0243	molybdopterin cofactor binding
RG54_RS13775	COG2885	chlorophyll binding
RG54_RS13790	COG2944	sequence-specific DNA binding
RG54_RS13795	COG1278	Cold shock
RG54_RS13820	COG3274	enterobacterial common antigen metabolic process
RG54_RS13825	COG4682	membrane
RG54_RS13830	COG4682	membrane
RG54_RS13835	COG1070	Carbohydrate kinase
RG54_RS13845	COG4213	ABC transporter substrate-binding protein
RG54_RS13850	COG1129	ABC transporter
RG54_RS13855	COG4214	carbohydrate transport
RG54_RS13860	COG1609	Transcriptional regulator
RG54_RS13860	COG2207	Transcriptional regulator
RG54_RS13865	COG2992	FlgJ-related protein
RG54_RS13870	COG0366	Alpha amylase catalytic
RG54_RS13875	COG3977	Valine--pyruvate aminotransferase
RG54_RS13880	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG54_RS13885	COG1414	Transcriptional regulator
RG54_RS13895	COG2731	YhcH YjgK YiaL family protein
RG54_RS13900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RG54_RS13905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RG54_RS13910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RG54_RS13915	COG1070	Carbohydrate kinase
RG54_RS13920	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RG54_RS13925	COG3623	hexulose-6-phosphate isomerase
RG54_RS13930	COG0235	Class ii aldolase
RG54_RS13935	COG3713	MltA-interacting MipA family protein
RG54_RS13940	COG0583	DNA-binding transcription factor activity
RG54_RS13945	COG1566	PFAM secretion protein HlyD family protein
RG54_RS13960	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS13965	COG1454	alcohol dehydrogenase
RG54_RS13970	COG3276	selenocysteine insertion sequence binding
RG54_RS13980	COG0625	glutathione transferase activity
RG54_RS13990	COG5433	transposase activity
RG54_RS13995	COG3209	COG3209 Rhs family protein
RG54_RS14010	COG3209	COG3209 Rhs family protein
RG54_RS14015	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
RG54_RS14040	COG1566	PFAM secretion protein HlyD family protein
RG54_RS14050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS14050	COG2213	PTS system mannitol-specific
RG54_RS14060	COG3722	fumarate hydratase activity
RG54_RS14085	COG5295	Hep Hag repeat protein
RG54_RS14090	COG1620	l-lactate permease
RG54_RS14095	COG2186	Transcriptional regulator
RG54_RS14105	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RG54_RS14110	COG1045	serine acetyltransferase
RG54_RS14125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RG54_RS14130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RG54_RS14145	COG4942	peptidase
RG54_RS14150	COG2861	carbohydrate metabolic process
RG54_RS14155	COG1216	Glycosyl transferase, family 2
RG54_RS14165	COG0156	8-amino-7-oxononanoate synthase activity
RG54_RS14175	COG0859	PFAM glycosyl transferase family 9
RG54_RS14180	COG0859	PFAM glycosyl transferase family 9
RG54_RS14195	COG1442	glycosyl transferase family 8
RG54_RS14200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RG54_RS14215	COG0515	serine threonine protein kinase
RG54_RS14220	COG0438	transferase activity, transferring glycosyl groups
RG54_RS14225	COG0859	PFAM glycosyl transferase family 9
RG54_RS14230	COG1519	Transferase
RG54_RS14260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RG54_RS14290	COG1561	YicC-like family, N-terminal region
RG54_RS14295	COG3645	SOS response
RG54_RS14300	COG2860	membrane
RG54_RS14310	COG0194	GDP metabolic process
RG54_RS14320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RG54_RS14325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RG54_RS14330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RG54_RS14340	COG0786	glutamate:sodium symporter activity
RG54_RS14345	COG2233	PERMEase
RG54_RS14350	COG2982	Protein involved in outer membrane biogenesis
RG54_RS14355	COG1501	Belongs to the glycosyl hydrolase 31 family
RG54_RS14360	COG2211	Major facilitator Superfamily
RG54_RS14375	COG2814	Major facilitator Superfamily
RG54_RS14380	COG0697	spore germination
RG54_RS14385	COG1464	Belongs to the NlpA lipoprotein family
RG54_RS14420	COG2252	PERMEase
RG54_RS14430	COG2271	Major facilitator Superfamily
RG54_RS14435	COG2271	Major facilitator Superfamily
RG54_RS14440	COG3851	Histidine kinase
RG54_RS14445	COG2197	response regulator
RG54_RS14450	COG0440	acetolactate synthase activity
RG54_RS14455	COG0028	Belongs to the TPP enzyme family
RG54_RS14490	COG2814	Major facilitator Superfamily
RG54_RS14495	COG0641	radical SAM
RG54_RS14505	COG2149	membrane
RG54_RS14515	COG3119	arylsulfatase activity
RG54_RS14520	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RG54_RS14525	COG2207	Transcriptional regulator
RG54_RS14545	COG2188	Transcriptional regulator
RG54_RS14570	COG5645	(Lipo)protein
RG54_RS14575	COG0823	Involved in the tonB-independent uptake of proteins
RG54_RS14585	COG2271	Major facilitator Superfamily
RG54_RS14595	COG0800	Aldolase
RG54_RS14600	COG3734	2-keto-3-deoxy-galactonokinase
RG54_RS14605	COG2186	Transcriptional regulator
RG54_RS14615	COG0561	phosphatase activity
RG54_RS14620	COG3753	Protein conserved in bacteria
RG54_RS14625	COG0187	DNA topoisomerase II activity
RG54_RS14635	COG0592	DNA-directed DNA polymerase activity
RG54_RS14685	COG0814	amino acid
RG54_RS14700	COG2091	lysine biosynthetic process via aminoadipic acid
RG54_RS14705	COG0431	NADPH-dependent FMN reductase
RG54_RS14710	COG2252	PERMEase
RG54_RS14715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG54_RS14725	COG3196	Protein conserved in bacteria
RG54_RS14730	COG0363	glucosamine-6-phosphate deaminase activity
RG54_RS14735	COG2382	esterase
RG54_RS14745	COG2723	6-phospho-beta-galactosidase activity
RG54_RS14750	COG2190	(PTS) system
RG54_RS14750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS14750	COG1263	PTS System
RG54_RS14755	COG3711	transcriptional antiterminator
RG54_RS14760	COG0704	Plays a role in the regulation of phosphate uptake
RG54_RS14765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RG54_RS14770	COG0581	inorganic phosphate transmembrane transporter activity
RG54_RS14775	COG0573	inorganic phosphate transmembrane transporter activity
RG54_RS14780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RG54_RS14790	COG3188	usher protein
RG54_RS14805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RG54_RS14860	COG3312	ion transport
RG54_RS14875	COG0716	FMN binding
RG54_RS14880	COG1522	sequence-specific DNA binding
RG54_RS14915	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG54_RS14920	COG1879	ABC-type sugar transport system periplasmic component
RG54_RS14925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG54_RS14930	COG1609	Transcriptional regulator
RG54_RS14935	COG0477	Major facilitator Superfamily
RG54_RS14940	COG2186	Transcriptional regulator
RG54_RS14985	COG3085	chromosome segregation
RG54_RS14990	COG0606	chelatase, subunit chli
RG54_RS15005	COG3978	acetolactate synthase activity
RG54_RS15010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RG54_RS15020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RG54_RS15025	COG0583	DNA-binding transcription factor activity
RG54_RS15035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RG54_RS15040	COG3692	DNA binding
RG54_RS15045	COG0210	DNA helicase
RG54_RS15065	COG3118	belongs to the thioredoxin family
RG54_RS15075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RG54_RS15085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RG54_RS15090	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
RG54_RS15095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RG54_RS15100	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RG54_RS15105	COG1088	dTDP-glucose 4,6-dehydratase activity
RG54_RS15110	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RG54_RS15115	COG0456	acetyltransferase
RG54_RS15120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RG54_RS15125	COG2244	polysaccharide biosynthetic process
RG54_RS15145	COG1113	amino acid transport
RG54_RS15170	COG0641	radical SAM
RG54_RS15175	COG3119	arylsulfatase activity
RG54_RS15180	COG3071	HemY protein
RG54_RS15185	COG2959	enzyme of heme biosynthesis
RG54_RS15190	COG1587	Uroporphyrinogen-III synthase
RG54_RS15205	COG3072	Adenylate cyclase
RG54_RS15225	COG5567	small periplasmic lipoprotein
RG54_RS15235	COG3159	Protein conserved in bacteria
RG54_RS15245	COG1011	Hydrolase
RG54_RS15250	COG0210	DNA helicase
RG54_RS15255	COG3698	Phosphodiester glycosidase
RG54_RS15265	COG0598	Magnesium transport protein CorA
RG54_RS15280	COG2962	Rard protein
RG54_RS15285	COG2050	protein possibly involved in aromatic compounds catabolism
RG54_RS15290	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
RG54_RS15295	COG0514	ATP-dependent DNA helicase (RecQ)
RG54_RS15300	COG1280	lysine exporter protein (LysE YggA)
RG54_RS15305	COG1280	lysine exporter protein (LysE YggA)
RG54_RS15310	COG2267	carboxylic ester hydrolase activity
RG54_RS15315	COG0561	phosphatase activity
RG54_RS15320	COG0697	spore germination
RG54_RS15325	COG0583	DNA-binding transcription factor activity
RG54_RS15335	COG0412	Dienelactone hydrolase
RG54_RS15340	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
RG54_RS15350	COG1322	Protein conserved in bacteria
RG54_RS15360	COG3165	ubiquinone biosynthetic process from chorismate
RG54_RS15370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RG54_RS15375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RG54_RS15380	COG0805	protein transport
RG54_RS15390	COG0250	Participates in transcription elongation, termination and antitermination
RG54_RS15395	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RG54_RS15400	COG0543	2 iron, 2 sulfur cluster binding
RG54_RS15420	COG1739	Uncharacterized protein family UPF0029
RG54_RS15425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RG54_RS15430	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
RG54_RS15460	COG1763	Mo-molybdopterin cofactor biosynthetic process
RG54_RS15465	COG0746	molybdenum cofactor guanylyltransferase activity
RG54_RS15470	COG3084	Protein conserved in bacteria
RG54_RS15475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RG54_RS15480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RG54_RS15485	COG5339	Protein conserved in bacteria
RG54_RS15490	COG0204	Acyl-transferase
RG54_RS15500	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RG54_RS15500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RG54_RS15520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RG54_RS15535	COG2204	response regulator
RG54_RS15540	COG3852	Histidine kinase
RG54_RS15545	COG0174	glutamine synthetase
RG54_RS15555	COG1217	gtp-binding protein TYPA
RG54_RS15560	COG2188	Transcriptional regulator
RG54_RS15565	COG1082	Xylose isomerase domain protein TIM barrel
RG54_RS15570	COG2271	Major facilitator Superfamily
RG54_RS15575	COG1349	DNA-binding transcription factor activity
RG54_RS15580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG54_RS15585	COG2084	Dehydrogenase
RG54_RS15590	COG3684	Belongs to the aldolase LacD family
RG54_RS15595	COG1063	alcohol dehydrogenase
RG54_RS15605	COG0477	Major facilitator Superfamily
RG54_RS15615	COG1011	Hydrolase
RG54_RS15630	COG0456	acetyltransferase
RG54_RS15640	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
RG54_RS15655	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RG54_RS15660	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RG54_RS15675	COG2864	formate dehydrogenase
RG54_RS15680	COG0437	4 iron, 4 sulfur cluster binding
RG54_RS15705	COG3711	transcriptional antiterminator
RG54_RS15705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS15710	COG1363	Peptidase, m42
RG54_RS15715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS15715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS15720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS15765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RG54_RS15785	COG2258	MOSC domain
RG54_RS15790	COG2205	protein histidine kinase activity
RG54_RS15795	COG0745	RESPONSE REGULATOR receiver
RG54_RS15800	COG3678	ATP-independent chaperone mediated protein folding
RG54_RS15825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RG54_RS15850	COG3152	Membrane
RG54_RS15855	COG3691	Protein conserved in bacteria
RG54_RS15860	COG0589	response to stress
RG54_RS15870	COG1494	fructose-1,6-bisphosphatase
RG54_RS15880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RG54_RS15895	COG1575	Belongs to the MenA family. Type 1 subfamily
RG54_RS15910	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RG54_RS15915	COG1609	Transcriptional regulator
RG54_RS15920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RG54_RS15930	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
RG54_RS15940	COG0626	cystathionine gamma-synthase activity
RG54_RS15945	COG0527	aspartate kinase activity
RG54_RS15945	COG0460	homoserine dehydrogenase
RG54_RS15955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RG54_RS15965	COG0697	spore germination
RG54_RS15970	COG3738	Protein conserved in bacteria
RG54_RS15980	COG0371	Dehydrogenase
RG54_RS15985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RG54_RS15990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS15990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS15990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RG54_RS15995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS16000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS16005	COG1882	Formate acetyltransferase
RG54_RS16010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RG54_RS16015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS16020	COG2207	Transcriptional regulator
RG54_RS16025	COG2194	sulfuric ester hydrolase activity
RG54_RS16040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RG54_RS16060	COG4948	Mandelate Racemase Muconate Lactonizing
RG54_RS16065	COG2271	Major facilitator Superfamily
RG54_RS16070	COG0583	DNA-binding transcription factor activity
RG54_RS16085	COG1309	transcriptional regulator
RG54_RS16140	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RG54_RS16140	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
RG54_RS16185	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RG54_RS16190	COG0250	Participates in transcription elongation, termination and antitermination
RG54_RS16235	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RG54_RS16245	COG2104	thiamine diphosphate biosynthetic process
RG54_RS16250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RG54_RS16285	COG3068	Protein conserved in bacteria
RG54_RS16300	COG3678	ATP-independent chaperone mediated protein folding
RG54_RS16310	COG4191	Histidine kinase
RG54_RS16315	COG2204	response regulator
RG54_RS16320	COG0151	Belongs to the GarS family
RG54_RS16360	COG0456	acetyltransferase
RG54_RS16370	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RG54_RS16375	COG2224	Isocitrate lyase
RG54_RS16400	COG1414	Transcriptional regulator
RG54_RS16405	COG1410	methionine synthase
RG54_RS16405	COG0646	methionine synthase
RG54_RS16410	COG1283	sodium-dependent phosphate transmembrane transporter activity
RG54_RS16435	COG3541	Predicted nucleotidyltransferase
RG54_RS16440	COG0542	response to heat
RG54_RS16445	COG0527	aspartate kinase activity
RG54_RS16475	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG54_RS16490	COG2814	Major facilitator Superfamily
RG54_RS16490	COG0477	Major facilitator Superfamily
RG54_RS16495	COG3833	ABC-type maltose transport systems, permease component
RG54_RS16500	COG1175	transmembrane transport
RG54_RS16505	COG2182	Extracellular solute-binding protein
RG54_RS16515	COG3842	ATPase activity
RG54_RS16535	COG1357	PFAM Pentapeptide repeats (8 copies)
RG54_RS16565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RG54_RS16575	COG0534	Mate efflux family protein
RG54_RS16580	COG3237	CsbD-like
RG54_RS16585	COG0735	belongs to the Fur family
RG54_RS16600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RG54_RS16610	COG0604	alcohol dehydrogenase
RG54_RS16615	COG0305	Participates in initiation and elongation during chromosome replication
RG54_RS16620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RG54_RS16625	COG3201	nicotinamide mononucleotide transporter
RG54_RS16635	COG1448	Aminotransferase
RG54_RS16650	COG3700	Belongs to the class B bacterial acid phosphatase family
RG54_RS16655	COG0432	Pfam Uncharacterised protein family UPF0047
RG54_RS16660	COG2315	Protein conserved in bacteria
RG54_RS16665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RG54_RS16675	COG0629	single-stranded DNA binding
RG54_RS16690	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RG54_RS16695	COG2207	Transcriptional regulator
RG54_RS16700	COG0789	Transcriptional regulator
RG54_RS16720	COG2252	PERMEase
RG54_RS16725	COG0025	NhaP-type Na H and K H
RG54_RS16730	COG1357	PFAM Pentapeptide repeats (8 copies)
RG54_RS16740	COG3162	membrane
RG54_RS16745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RG54_RS16760	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
RG54_RS16765	COG0437	4 iron, 4 sulfur cluster binding
RG54_RS16770	COG3301	Polysulphide reductase, NrfD
RG54_RS16775	COG1138	Cytochrome C-type biogenesis protein
RG54_RS16780	COG3088	subunit of a heme lyase
RG54_RS16785	COG4235	cytochrome complex assembly
RG54_RS16795	COG1301	dicarboxylic acid transport
RG54_RS16800	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
RG54_RS16815	COG1289	transmembrane transporter activity
RG54_RS16820	COG1566	PFAM secretion protein HlyD family protein
RG54_RS16835	COG0698	ribose 5-phosphate isomerase
RG54_RS16845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RG54_RS16850	COG0456	acetyltransferase
RG54_RS16855	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RG54_RS16860	COG3454	Phosphonate metabolism
RG54_RS16865	COG4778	phosphonate C-P lyase system protein PhnL
RG54_RS16875	COG4107	phosphonate C-P lyase system protein PhnK
RG54_RS16880	COG3627	carbon phosphorus lyase activity
RG54_RS16885	COG3626	phosphonate metabolism
RG54_RS16890	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
RG54_RS16895	COG3624	Phosphonate C-P lyase system protein PhnG
RG54_RS16900	COG2188	Transcriptional regulator
RG54_RS16905	COG3639	organic phosphonate transmembrane transporter activity
RG54_RS16910	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
RG54_RS16920	COG2764	glyoxalase bleomycin resistance protein dioxygenase
RG54_RS16925	COG2824	Alkylphosphonate utilization operon protein PhnA
RG54_RS16945	COG0477	Major facilitator Superfamily
RG54_RS16955	COG0642	Histidine kinase
RG54_RS16960	COG0745	RESPONSE REGULATOR receiver
RG54_RS16965	COG2194	sulfuric ester hydrolase activity
RG54_RS16970	COG0531	amino acid
RG54_RS16975	COG2207	Transcriptional regulator
RG54_RS16985	COG2169	Transcriptional regulator
RG54_RS16995	COG1486	melibiose metabolic process
RG54_RS17000	COG2211	Major facilitator Superfamily
RG54_RS17005	COG3647	Membrane
RG54_RS17010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RG54_RS17010	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RG54_RS17015	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RG54_RS17025	COG4565	transcriptional regulatory protein
RG54_RS17030	COG3290	protein histidine kinase activity
RG54_RS17060	COG2801	Transposase and inactivated derivatives
RG54_RS17100	COG3468	outer membrane autotransporter barrel domain protein
RG54_RS17100	COG3210	domain, Protein
RG54_RS17115	COG2388	GCN5-related N-acetyl-transferase
RG54_RS17135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RG54_RS17140	COG3104	oligopeptide transport
RG54_RS17145	COG1982	Orn Lys Arg decarboxylase major
RG54_RS17150	COG0531	amino acid
RG54_RS17160	COG3710	Transcriptional regulator
RG54_RS17205	COG2003	Belongs to the UPF0758 family
RG54_RS17220	COG4372	Transposase
RG54_RS17225	COG3436	PFAM IS66 Orf2 family protein
RG54_RS17250	COG2020	methyltransferase activity
RG54_RS17255	COG3468	outer membrane autotransporter barrel domain protein
RG54_RS17265	COG4983	Phage plasmid primase, P4 family domain protein
RG54_RS17365	COG2831	hemolysin activation secretion protein
RG54_RS17370	COG2994	toxin metabolic process
RG54_RS17375	COG3210	domain, Protein
RG54_RS17385	COG3210	domain, Protein
RG54_RS17425	COG3969	phosphoadenosine phosphosulfate
RG54_RS17435	COG3037	sugar-specific permease SgaT UlaA
RG54_RS17445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS17460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RG54_RS17465	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS17475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RG54_RS17500	COG1216	Glycosyl transferase, family 2
RG54_RS17505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RG54_RS17520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RG54_RS17530	COG0204	Acyl-transferase
RG54_RS17615	COG4372	Transposase
RG54_RS17620	COG3436	PFAM IS66 Orf2 family protein
RG54_RS17640	COG3385	transposase activity
RG54_RS17650	COG0582	viral genome integration into host DNA
RG54_RS17660	COG1309	transcriptional regulator
RG54_RS17675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RG54_RS17680	COG1027	Aspartate ammonia-lyase
RG54_RS17690	COG3030	protein affecting phage T7 exclusion by the F plasmid
RG54_RS17695	COG0531	amino acid
RG54_RS17720	COG1509	lysine 2,3-aminomutase activity
RG54_RS17730	COG5510	response to toxic substance
RG54_RS17735	COG5510	response to toxic substance
RG54_RS17740	COG2076	Multidrug Resistance protein
RG54_RS17745	COG3040	lipid binding
RG54_RS17750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RG54_RS17765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RG54_RS17770	COG1053	succinate dehydrogenase
RG54_RS17780	COG0531	amino acid
RG54_RS17785	COG3264	Mechanosensitive ion channel
RG54_RS17785	COG1511	domain protein
RG54_RS17820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RG54_RS17825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RG54_RS17825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RG54_RS17830	COG0802	atpase or kinase
RG54_RS17835	COG0860	N-Acetylmuramoyl-L-alanine amidase
RG54_RS17855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RG54_RS17860	COG0330	HflC and HflK could
RG54_RS17865	COG0330	HflC and HflK could
RG54_RS17870	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
RG54_RS17885	COG0557	exoribonuclease II activity
RG54_RS17890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RG54_RS17895	COG3789	protein conserved in bacteria
RG54_RS17900	COG1842	Phage shock protein A
RG54_RS17910	COG3766	membrane
RG54_RS17915	COG5463	Belongs to the UPF0441 family
RG54_RS17920	COG0754	glutathionylspermidine amidase activity
RG54_RS17925	COG1960	acyl-CoA dehydrogenase activity
RG54_RS17940	COG3650	response to hydrogen peroxide
RG54_RS17945	COG1073	alpha beta
RG54_RS17960	COG3037	sugar-specific permease SgaT UlaA
RG54_RS17990	COG3477	response to acidic pH
RG54_RS18010	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RG54_RS18020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RG54_RS18030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RG54_RS18035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RG54_RS18040	COG4670	ketone body catabolic process
RG54_RS18045	COG1024	Enoyl-CoA hydratase
RG54_RS18060	COG1309	transcriptional regulator
RG54_RS18065	COG3061	Opacity-associated protein A
RG54_RS18075	COG0545	Peptidyl-prolyl cis-trans isomerase
RG54_RS18080	COG1113	amino acid transport
RG54_RS18090	COG0697	spore germination
RG54_RS18095	COG0702	epimerase
RG54_RS18100	COG1733	regulation of RNA biosynthetic process
RG54_RS18105	COG0737	Belongs to the 5'-nucleotidase family
RG54_RS18110	COG1218	3'(2'),5'-bisphosphate nucleotidase
RG54_RS18115	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
RG54_RS18125	COG1253	flavin adenine dinucleotide binding
RG54_RS18140	COG0729	surface antigen
RG54_RS18145	COG2911	Protein conserved in bacteria
RG54_RS18150	COG2105	PFAM AIG2 family protein
RG54_RS18155	COG2336	PFAM SpoVT AbrB
RG54_RS18160	COG2337	Toxic component of a toxin-antitoxin (TA) module
RG54_RS18165	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RG54_RS18170	COG1879	ABC-type sugar transport system periplasmic component
RG54_RS18175	COG1129	ABC transporter
RG54_RS18180	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG54_RS18185	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG54_RS18195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RG54_RS18205	COG0312	modulator of DNA gyrase
RG54_RS18210	COG3783	Cytochrome b(562)
RG54_RS18215	COG0602	queuosine metabolic process
RG54_RS18225	COG1328	CTP reductase activity
RG54_RS18230	COG0366	Alpha amylase catalytic
RG54_RS18235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS18235	COG1263	PTS System
RG54_RS18240	COG1609	Transcriptional regulator
RG54_RS18245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RG54_RS18250	COG0251	oxidation-reduction process
RG54_RS18275	COG0251	oxidation-reduction process
RG54_RS18280	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS18285	COG1309	transcriptional regulator
RG54_RS18290	COG2731	YhcH YjgK YiaL family protein
RG54_RS18305	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
RG54_RS18310	COG0456	acetyltransferase
RG54_RS18315	COG4269	membrane
RG54_RS18320	COG0525	valine-tRNA ligase activity
RG54_RS18325	COG2927	DNA polymerase III (CHI subunit)
RG54_RS18340	COG0795	lipopolysaccharide-transporting ATPase activity
RG54_RS18345	COG0795	lipopolysaccharide-transporting ATPase activity
RG54_RS18350	COG0433	COG0433 Predicted ATPase
RG54_RS18355	COG1064	alcohol dehydrogenase
RG54_RS18420	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RG54_RS18430	COG0582	viral genome integration into host DNA
RG54_RS18435	COG4974	Belongs to the 'phage' integrase family
RG54_RS18445	COG3539	Fimbrial protein
RG54_RS18450	COG3539	Fimbrial protein
RG54_RS18455	COG3121	Chaperone
RG54_RS18460	COG3188	usher protein
RG54_RS18465	COG3539	Fimbrial protein
RG54_RS18470	COG3539	Fimbrial protein
RG54_RS18475	COG3539	Fimbrial protein
RG54_RS18485	COG2610	gluconate transmembrane transporter activity
RG54_RS18500	COG0246	Mannitol dehydrogenase
RG54_RS18510	COG2186	Transcriptional regulator
RG54_RS18535	COG0583	DNA-binding transcription factor activity
RG54_RS18540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RG54_RS18545	COG0700	Nucleoside recognition
RG54_RS18550	COG3366	ferrous iron transmembrane transporter activity
RG54_RS18565	COG0477	Major facilitator Superfamily
RG54_RS18580	COG1924	4 iron, 4 sulfur cluster binding
RG54_RS18585	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
RG54_RS18590	COG2733	membrane
RG54_RS18595	COG2814	Major facilitator Superfamily
RG54_RS18605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RG54_RS18610	COG5457	Domain of unknown function (DUF1127)
RG54_RS18620	COG0523	cobalamin synthesis protein
RG54_RS18625	COG2879	small protein
RG54_RS18630	COG1966	Carbon starvation protein
RG54_RS18635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RG54_RS18640	COG2368	4-hydroxyphenylacetate
RG54_RS18660	COG3971	2-oxopent-4-enoate hydratase activity
RG54_RS18670	COG3384	dioxygenase
RG54_RS18675	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS18680	COG0179	Fumarylacetoacetate (FAA) hydrolase
RG54_RS18685	COG1846	Transcriptional regulator
RG54_RS18690	COG0840	transmembrane signaling receptor activity
RG54_RS18695	COG2271	Major facilitator Superfamily
RG54_RS18700	COG1802	Transcriptional regulator
RG54_RS18705	COG1063	alcohol dehydrogenase
RG54_RS18720	COG1484	DNA-dependent DNA replication
RG54_RS18735	COG2966	Psort location CytoplasmicMembrane, score
RG54_RS18740	COG2197	response regulator
RG54_RS18745	COG2197	response regulator
RG54_RS18750	COG4114	ferric iron reductase
RG54_RS18785	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
RG54_RS18790	COG0456	acetyltransferase
RG54_RS18795	COG1011	Hydrolase
RG54_RS18805	COG2823	Periplasmic or secreted lipoprotein
RG54_RS18815	COG4667	esterase of the alpha-beta hydrolase superfamily
RG54_RS18820	COG0084	hydrolase, TatD family'
RG54_RS18825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RG54_RS18830	COG1328	CTP reductase activity
RG54_RS18870	COG0560	Phosphoserine phosphatase
RG54_RS18875	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RG54_RS18880	COG1056	cytidyltransferase-related domain
RG54_RS18880	COG3172	ATPase kinase involved in NAD metabolism
RG54_RS18890	COG0488	(ABC) transporter
RG54_RS18900	COG0741	lytic transglycosylase activity
RG54_RS18920	COG2207	Transcriptional regulator
RG54_RS18920	COG3708	Transcriptional regulator
RG54_RS18925	COG3045	CreA protein
RG54_RS18930	COG0745	RESPONSE REGULATOR receiver
RG54_RS18935	COG2205	protein histidine kinase activity
RG54_RS18940	COG4452	Inner membrane protein CreD
RG54_RS18945	COG0745	RESPONSE REGULATOR receiver
RG54_RS18955	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
RG54_RS18965	COG0460	homoserine dehydrogenase
RG54_RS18965	COG0527	aspartate kinase activity
RG54_RS18975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RG54_RS18995	COG1115	amino acid carrier protein
RG54_RS19005	COG0521	Mo-molybdopterin cofactor biosynthetic process
RG54_RS19010	COG1584	GPR1 FUN34 yaaH family protein
RG54_RS19015	COG4735	regulation of single-species biofilm formation
RG54_RS19045	COG0583	DNA-binding transcription factor activity
RG54_RS19055	COG3188	usher protein
RG54_RS19080	COG0196	riboflavin kinase activity
RG54_RS19095	COG1047	Peptidyl-prolyl cis-trans
RG54_RS19115	COG0505	Belongs to the CarA family
RG54_RS19120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RG54_RS19175	COG0644	oxidoreductase
RG54_RS19180	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
RG54_RS19185	COG2271	Major facilitator Superfamily
RG54_RS19200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RG54_RS19225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RG54_RS19230	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RG54_RS19235	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RG54_RS19240	COG0564	pseudouridine synthase activity
RG54_RS19250	COG0417	DNA replication proofreading
RG54_RS19255	COG0235	Class ii aldolase
RG54_RS19275	COG4977	sequence-specific DNA binding
RG54_RS19280	COG0586	Pfam SNARE associated Golgi protein
RG54_RS19290	COG1178	ABC-type Fe3 transport system permease component
RG54_RS19295	COG4143	(ABC) transporter
RG54_RS19310	COG2814	Major facilitator Superfamily
RG54_RS19325	COG0473	3-isopropylmalate dehydrogenase activity
RG54_RS19340	COG0583	DNA-binding transcription factor activity
RG54_RS19345	COG0028	Belongs to the TPP enzyme family
RG54_RS19350	COG0440	acetolactate synthase activity
RG54_RS19360	COG1609	Transcriptional regulator
RG54_RS19380	COG3116	cell division
RG54_RS19385	COG0768	penicillin binding
RG54_RS19390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RG54_RS19395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RG54_RS19410	COG0772	Belongs to the SEDS family
RG54_RS19425	COG1181	Belongs to the D-alanine--D-alanine ligase family
RG54_RS19430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RG54_RS19435	COG0849	cell division
RG54_RS19440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RG54_RS19460	COG0494	nUDIX hydrolase
RG54_RS19475	COG0237	dephospho-CoA kinase activity
RG54_RS19485	COG1459	type II secretion system
RG54_RS19490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RG54_RS19495	COG4969	Belongs to the N-Me-Phe pilin family
RG54_RS19505	COG0157	Belongs to the NadC ModD family
RG54_RS19510	COG3023	N-Acetylmuramoyl-L-alanine amidase
RG54_RS19515	COG3725	Membrane protein required for beta-lactamase induction
RG54_RS19520	COG1113	amino acid transport
RG54_RS19525	COG2186	Transcriptional regulator
RG54_RS19535	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RG54_RS19540	COG0508	dehydrogenase complex catalyzes the overall conversion of
RG54_RS19545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RG54_RS19550	COG3064	Membrane
RG54_RS19560	COG1049	propionate catabolic process, 2-methylcitrate cycle
RG54_RS19585	COG2132	Multicopper oxidase
RG54_RS19590	COG4993	Dehydrogenase
RG54_RS19595	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RG54_RS19600	COG0288	reversible hydration of carbon dioxide
RG54_RS19605	COG1131	(ABC) transporter
RG54_RS19610	COG0842	Transport permease protein
RG54_RS19615	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS19620	COG0726	polysaccharide deacetylase
RG54_RS19640	COG5464	transposase or invertase
RG54_RS19655	COG3539	Fimbrial protein
RG54_RS19660	COG3539	Fimbrial protein
RG54_RS19665	COG3539	Fimbrial protein
RG54_RS19670	COG3539	Fimbrial protein
RG54_RS19675	COG3188	usher protein
RG54_RS19680	COG3121	Chaperone
RG54_RS19685	COG3539	Fimbrial protein
RG54_RS19690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RG54_RS19695	COG0617	tRNA 3'-terminal CCA addition
RG54_RS19705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RG54_RS19715	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RG54_RS19720	COG1643	Atp-dependent helicase
RG54_RS19730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RG54_RS19735	COG4774	siderophore transport
RG54_RS19740	COG1120	ATPase activity
RG54_RS19745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RG54_RS19770	COG2860	membrane
RG54_RS19775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RG54_RS19795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RG54_RS19800	COG3835	regulator
RG54_RS19820	COG0024	Methionine aminopeptidase
RG54_RS19855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RG54_RS19860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RG54_RS19865	COG0575	Belongs to the CDS family
RG54_RS19870	COG0750	zinc metalloprotease
RG54_RS19880	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
RG54_RS19885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RG54_RS19910	COG0587	DNA-directed DNA polymerase activity
RG54_RS19920	COG1982	Orn Lys Arg decarboxylase major
RG54_RS19925	COG0346	lactoylglutathione lyase activity
RG54_RS19935	COG4568	rho-dependent transcription termination
RG54_RS19945	COG4681	YaeQ
RG54_RS19950	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RG54_RS19955	COG3015	lipoprotein NlpE involved in copper resistance
RG54_RS19970	COG1720	tRNA m6t6A37 methyltransferase activity
RG54_RS19980	COG1464	Belongs to the NlpA lipoprotein family
RG54_RS19985	COG2011	ABC-type metal ion transport system permease component
RG54_RS19990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RG54_RS19995	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RG54_RS20030	COG0582	viral genome integration into host DNA
RG54_RS20045	COG0582	viral genome integration into host DNA
RG54_RS20070	COG3093	addiction module antidote protein HigA
RG54_RS20155	COG2885	chlorophyll binding
RG54_RS20205	COG3209	COG3209 Rhs family protein
RG54_RS20220	COG5433	transposase activity
RG54_RS20225	COG0656	L-ascorbic acid biosynthetic process
RG54_RS20230	COG0583	DNA-binding transcription factor activity
RG54_RS20240	COG2226	methyltransferase
RG54_RS20245	COG0741	lytic transglycosylase activity
RG54_RS20245	COG1388	LysM domain
RG54_RS20255	COG2226	methyltransferase
RG54_RS20265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG54_RS20275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RG54_RS20285	COG1960	acyl-CoA dehydrogenase activity
RG54_RS20295	COG0121	glutamine amidotransferase
RG54_RS20300	COG3034	peptidoglycan biosynthetic process
RG54_RS20305	COG3041	Addiction module toxin RelE StbE family
RG54_RS20310	COG3077	Addiction module antitoxin, RelB DinJ family
RG54_RS20315	COG0791	NLP P60 protein
RG54_RS20345	COG1987	bacterial-type flagellum assembly
RG54_RS20370	COG1677	Flagellar hook-basal body complex protein FliE
RG54_RS20380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RG54_RS20400	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RG54_RS20430	COG1815	bacterial-type flagellum-dependent cell motility
RG54_RS20435	COG1558	bacterial-type flagellum-dependent cell motility
RG54_RS20445	COG1749	Flagellar hook protein flgE
RG54_RS20450	COG4787	bacterial-type flagellum-dependent cell motility
RG54_RS20455	COG4786	Flagellar basal body rod
RG54_RS20480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RG54_RS20500	COG2842	Transposition protein
RG54_RS20520	COG4396	Host-nuclease inhibitor protein Gam
RG54_RS20610	COG4373	Mu-like prophage FluMu protein gp28
RG54_RS20615	COG4383	Mu-like prophage protein gp29
RG54_RS20620	COG2369	cell adhesion
RG54_RS20625	COG5005	Phage virion morphogenesis
RG54_RS20630	COG4388	Caudovirus prohead serine protease
RG54_RS20635	COG4397	Mu-like prophage major head subunit gpT
RG54_RS20665	COG4386	tail sheath protein
RG54_RS20675	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
RG54_RS20685	COG4228	DNA circulation
RG54_RS20695	COG4384	Bacteriophage Mu Gp45 protein
RG54_RS20705	COG3299	homolog of phage Mu protein gp47
RG54_RS20770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RG54_RS20780	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RG54_RS20805	COG1191	sigma factor activity
RG54_RS20810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RG54_RS20825	COG0454	-acetyltransferase
RG54_RS20835	COG1690	Belongs to the RtcB family
RG54_RS20840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RG54_RS20855	COG2195	Cleaves the N-terminal amino acid of tripeptides
RG54_RS20875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RG54_RS20910	COG3093	addiction module antidote protein HigA
RG54_RS20930	COG3846	protein secretion by the type IV secretion system
RG54_RS20940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RG54_RS20980	COG0583	DNA-binding transcription factor activity
RG54_RS20985	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RG54_RS20990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RG54_RS20995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RG54_RS21000	COG2080	2 iron, 2 sulfur cluster binding
RG54_RS21010	COG3477	response to acidic pH
RG54_RS21020	COG0727	PFAM Uncharacterised protein family (UPF0153)
RG54_RS21025	COG3121	Chaperone
RG54_RS21035	COG3188	usher protein
RG54_RS21085	COG1388	LysM domain
RG54_RS21090	COG3708	Transcriptional regulator
RG54_RS21090	COG2207	Transcriptional regulator
RG54_RS21095	COG3059	membrane
RG54_RS21105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RG54_RS21110	COG2207	Transcriptional regulator
RG54_RS21115	COG0247	lactate metabolic process
RG54_RS21120	COG1139	Iron-sulfur cluster binding protein
RG54_RS21125	COG1556	Lactate utilization protein
RG54_RS21165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RG54_RS21175	COG2200	EAL domain
RG54_RS21175	COG2771	luxR family
RG54_RS21180	COG0583	DNA-binding transcription factor activity
RG54_RS21195	COG0666	response to abiotic stimulus
RG54_RS21205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RG54_RS21210	COG1304	FMN binding
RG54_RS21215	COG0549	Belongs to the carbamate kinase family
RG54_RS21220	COG0402	S-adenosylhomocysteine deaminase activity
RG54_RS21230	COG1879	ABC-type sugar transport system periplasmic component
RG54_RS21235	COG1129	ABC transporter
RG54_RS21240	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG54_RS21250	COG1064	alcohol dehydrogenase
RG54_RS21265	COG1280	lysine exporter protein (LysE YggA)
RG54_RS21275	COG3829	transcription factor binding
RG54_RS21280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RG54_RS21285	COG0372	Belongs to the citrate synthase family
RG54_RS21290	COG2079	MmgE PrpD family protein
RG54_RS21295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RG54_RS21300	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RG54_RS21305	COG0402	S-adenosylhomocysteine deaminase activity
RG54_RS21310	COG0583	DNA-binding transcription factor activity
RG54_RS21315	COG0288	reversible hydration of carbon dioxide
RG54_RS21325	COG2807	transmembrane transport
RG54_RS21330	COG2223	nitrite transmembrane transporter activity
RG54_RS21345	COG1609	Transcriptional regulator
RG54_RS21350	COG1414	Transcriptional regulator
RG54_RS21390	COG2814	Major facilitator Superfamily
RG54_RS21395	COG3122	Protein conserved in bacteria
RG54_RS21430	COG1215	transferase activity, transferring glycosyl groups
RG54_RS21435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RG54_RS21445	COG4521	taurine ABC transporter
RG54_RS21450	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RG54_RS21455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RG54_RS21460	COG2175	clavaminate synthase activity
RG54_RS21465	COG0113	porphobilinogen synthase activity
RG54_RS21475	COG3468	outer membrane autotransporter barrel domain protein
RG54_RS21480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RG54_RS21485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RG54_RS21495	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
RG54_RS21515	COG1181	Belongs to the D-alanine--D-alanine ligase family
RG54_RS21530	COG1785	Belongs to the alkaline phosphatase family
RG54_RS21540	COG3706	GGDEF domain
RG54_RS21545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RG54_RS21570	COG4126	flavin adenine dinucleotide binding
RG54_RS21595	COG1940	carbohydrate kinase activity
RG54_RS21600	COG2814	Major facilitator Superfamily
RG54_RS21605	COG0419	ATPase involved in DNA repair
RG54_RS21610	COG0420	3'-5' exonuclease activity
RG54_RS21615	COG0745	RESPONSE REGULATOR receiver
RG54_RS21620	COG5002	protein histidine kinase activity
RG54_RS21625	COG1114	Component of the transport system for branched-chain amino acids
RG54_RS21630	COG1113	amino acid transport
RG54_RS21635	COG0366	Alpha amylase catalytic
RG54_RS21655	COG1862	Preprotein translocase
RG54_RS21660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RG54_RS21665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RG54_RS21670	COG1403	HNH endonuclease
RG54_RS21675	COG3248	Nucleoside-binding outer membrane protein
RG54_RS21680	COG4238	major outer membrane lipoprotein
RG54_RS21690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RG54_RS21690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RG54_RS21705	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RG54_RS21710	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RG54_RS21715	COG0667	Aldo Keto reductase
RG54_RS21725	COG0142	geranyltranstransferase activity
RG54_RS21740	COG0693	protein deglycase activity
RG54_RS21745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RG54_RS21755	COG2814	Major facilitator Superfamily
RG54_RS21765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RG54_RS21770	COG1845	cytochrome c oxidase, subunit III
RG54_RS21775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RG54_RS21780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RG54_RS21785	COG2223	nitrite transmembrane transporter activity
RG54_RS21790	COG3056	Lipoprotein
RG54_RS21795	COG0271	Belongs to the BolA IbaG family
RG54_RS21820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RG54_RS21825	COG0776	regulation of translation
RG54_RS21830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RG54_RS21835	COG1555	photosystem II stabilization
RG54_RS21840	COG0824	Thioesterase
RG54_RS21850	COG4533	DNA binding
RG54_RS21860	COG1522	sequence-specific DNA binding
RG54_RS21865	COG1132	(ABC) transporter
RG54_RS21870	COG1132	(ABC) transporter
RG54_RS21875	COG0347	Belongs to the P(II) protein family
RG54_RS21880	COG0004	ammonium transporteR
RG54_RS21885	COG1946	Acyl-CoA thioesterase
RG54_RS21890	COG3126	Type III secretion system lipoprotein chaperone (YscW)
RG54_RS21895	COG3695	enzyme binding
RG54_RS21905	COG5507	3-demethylubiquinone-9 3-methyltransferase
RG54_RS21910	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RG54_RS21920	COG0110	maltose O-acetyltransferase activity
RG54_RS21935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG54_RS21940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG54_RS21945	COG1309	transcriptional regulator
RG54_RS21955	COG3264	Mechanosensitive ion channel
RG54_RS21955	COG1196	nuclear chromosome segregation
RG54_RS21970	COG3923	Primosomal replication protein n
RG54_RS21975	COG2832	Protein of unknown function (DUF454)
RG54_RS21990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RG54_RS22025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG54_RS22030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RG54_RS22030	COG4651	solute:proton antiporter activity
RG54_RS22035	COG2223	nitrite transmembrane transporter activity
RG54_RS22045	COG0737	Belongs to the 5'-nucleotidase family
RG54_RS22050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RG54_RS22055	COG3735	TraB family
RG54_RS22060	COG3093	addiction module antidote protein HigA
RG54_RS22075	COG2217	Heavy metal translocating P-type atpase
RG54_RS22080	COG2066	Belongs to the glutaminase family
RG54_RS22085	COG0531	amino acid
RG54_RS22090	COG0789	Transcriptional regulator
RG54_RS22095	COG1585	Membrane protein implicated in regulation of membrane protease activity
RG54_RS22100	COG0330	HflC and HflK could
RG54_RS22105	COG4619	ABC transporter
RG54_RS22110	COG0390	transport system, permease component
RG54_RS22115	COG3118	belongs to the thioredoxin family
RG54_RS22120	COG0300	oxidoreductase activity
RG54_RS22125	COG2755	lipolytic protein G-D-S-L family
RG54_RS22130	COG4181	ATPase activity
RG54_RS22135	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RG54_RS22150	COG0583	DNA-binding transcription factor activity
RG54_RS22160	COG1414	Transcriptional regulator
RG54_RS22165	COG3960	tartronate-semialdehyde synthase activity
RG54_RS22170	COG3622	Belongs to the hyi family
RG54_RS22175	COG2084	Dehydrogenase
RG54_RS22180	COG1953	Uracil, thiamine, allantoin
RG54_RS22190	COG2233	PERMEase
RG54_RS22195	COG1929	Belongs to the glycerate kinase type-1 family
RG54_RS22200	COG3257	ureidoglycine aminohydrolase activity
RG54_RS22205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RG54_RS22210	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RG54_RS22215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RG54_RS22220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RG54_RS22230	COG0549	Belongs to the carbamate kinase family
RG54_RS22235	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RG54_RS22240	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RG54_RS22255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RG54_RS22265	COG1988	membrane-bound metal-dependent
RG54_RS22270	COG2501	S4 domain
RG54_RS22280	COG3539	Fimbrial protein
RG54_RS22285	COG3121	Chaperone
RG54_RS22290	COG3188	usher protein
RG54_RS22295	COG3539	Fimbrial protein
RG54_RS22300	COG3539	Fimbrial protein
RG54_RS22305	COG2197	response regulator
RG54_RS22315	COG2207	Transcriptional regulator
RG54_RS22330	COG4783	chaperone-mediated protein folding
RG54_RS22335	COG1215	transferase activity, transferring glycosyl groups
RG54_RS22340	COG5002	protein histidine kinase activity
RG54_RS22345	COG0745	RESPONSE REGULATOR receiver
RG54_RS22355	COG1538	Outer membrane efflux protein
RG54_RS22360	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG54_RS22365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG54_RS22370	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG54_RS22375	COG1113	amino acid transport
RG54_RS22380	COG0668	transmembrane transport
RG54_RS22385	COG0778	Nitroreductase
RG54_RS22390	COG2315	Protein conserved in bacteria
RG54_RS22430	COG2977	Belongs to the P-Pant transferase superfamily
RG54_RS22435	COG4771	TonB-dependent receptor
RG54_RS22445	COG2382	esterase
RG54_RS22450	COG3251	PFAM MbtH domain protein
RG54_RS22455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RG54_RS22455	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RG54_RS22460	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
RG54_RS22465	COG1120	ATPase activity
RG54_RS22470	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RG54_RS22475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RG54_RS22485	COG4592	Periplasmic binding protein
RG54_RS22495	COG1169	isochorismate synthase
RG54_RS22500	COG1021	2,3-dihydroxybenzoate-AMP ligase
RG54_RS22505	COG1535	isochorismatase
RG54_RS22505	COG3433	isochorismatase activity
RG54_RS22510	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS22515	COG2050	protein possibly involved in aromatic compounds catabolism
RG54_RS22520	COG1966	Carbon starvation protein
RG54_RS22525	COG2879	small protein
RG54_RS22530	COG0371	Dehydrogenase
RG54_RS22535	COG0436	Aminotransferase
RG54_RS22540	COG1475	DNA binding
RG54_RS22545	COG3969	phosphoadenosine phosphosulfate
RG54_RS22550	COG0583	DNA-binding transcription factor activity
RG54_RS22555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RG54_RS22560	COG0450	alkyl hydroperoxide reductase
RG54_RS22570	COG3634	alkyl hydroperoxide reductase activity
RG54_RS22575	COG0589	response to stress
RG54_RS22580	COG1063	alcohol dehydrogenase
RG54_RS22590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RG54_RS22600	COG3719	Belongs to the RNase T2 family
RG54_RS22605	COG0471	metal ion transport
RG54_RS22620	COG3051	citrate lyase alpha subunit
RG54_RS22625	COG2301	Belongs to the HpcH HpaI aldolase family
RG54_RS22635	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
RG54_RS22640	COG3290	protein histidine kinase activity
RG54_RS22645	COG4565	transcriptional regulatory protein
RG54_RS22650	COG3069	C4-dicarboxylate transmembrane transporter activity
RG54_RS22675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RG54_RS22680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RG54_RS22695	COG0583	DNA-binding transcription factor activity
RG54_RS22715	COG1686	Belongs to the peptidase S11 family
RG54_RS22720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RG54_RS22725	COG0772	Belongs to the SEDS family
RG54_RS22730	COG0768	penicillin binding
RG54_RS22740	COG0799	negative regulation of ribosome biogenesis
RG54_RS22745	COG0406	alpha-ribazole phosphatase activity
RG54_RS22755	COG1466	dna polymerase III delta subunit
RG54_RS22770	COG2888	peptidyl-tyrosine sulfation
RG54_RS22775	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
RG54_RS22785	COG2214	Heat shock protein DnaJ domain protein
RG54_RS22790	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
RG54_RS22800	COG2214	Heat shock protein DnaJ domain protein
RG54_RS22805	COG0443	Heat shock 70 kDa protein
RG54_RS22815	COG1126	abc transporter atp-binding protein
RG54_RS22820	COG0765	amino acid transport
RG54_RS22825	COG0765	amino acid transport
RG54_RS22830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG54_RS22845	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RG54_RS22850	COG4535	Mg2 and Co2 transporter CorC
RG54_RS22860	COG1702	phosphate starvation-inducible protein PhoH
RG54_RS22870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RG54_RS22920	COG0367	asparagine synthase
RG54_RS22930	COG0647	UMP catabolic process
RG54_RS22935	COG1940	carbohydrate kinase activity
RG54_RS22935	COG1846	Transcriptional regulator
RG54_RS22940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RG54_RS22950	COG1263	PTS System
RG54_RS22950	COG2190	(PTS) system
RG54_RS22950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS22975	COG0735	belongs to the Fur family
RG54_RS22990	COG0716	FMN binding
RG54_RS23000	COG0596	Alpha beta hydrolase
RG54_RS23005	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
RG54_RS23010	COG0033	Phosphoglucomutase
RG54_RS23015	COG0531	amino acid
RG54_RS23020	COG1982	Orn Lys Arg decarboxylase major
RG54_RS23035	COG0745	RESPONSE REGULATOR receiver
RG54_RS23040	COG2205	protein histidine kinase activity
RG54_RS23070	COG5433	transposase activity
RG54_RS23080	COG3209	COG3209 Rhs family protein
RG54_RS23095	COG3272	Protein of unknown function (DUF1722)
RG54_RS23100	COG0415	Belongs to the DNA photolyase family
RG54_RS23110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RG54_RS23115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RG54_RS23120	COG1984	allophanate hydrolase subunit 2
RG54_RS23135	COG3180	Ammonia monooxygenase
RG54_RS23140	COG3539	Fimbrial protein
RG54_RS23145	COG3121	Chaperone
RG54_RS23150	COG3188	usher protein
RG54_RS23155	COG3539	Fimbrial protein
RG54_RS23160	COG0372	Belongs to the citrate synthase family
RG54_RS23180	COG2009	succinate dehydrogenase
RG54_RS23185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
RG54_RS23190	COG1053	succinate dehydrogenase
RG54_RS23195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RG54_RS23205	COG0567	Dehydrogenase, E1 component
RG54_RS23210	COG0508	dehydrogenase complex catalyzes the overall conversion of
RG54_RS23220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RG54_RS23225	COG2188	Transcriptional regulator
RG54_RS23230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG54_RS23230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS23230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG54_RS23235	COG0383	alpha-mannosidase activity
RG54_RS23245	COG1271	oxidase subunit
RG54_RS23250	COG1294	oxidase, subunit
RG54_RS23255	COG4890	Cyd operon protein YbgT
RG54_RS23260	COG3790	cyd operon protein YbgE
RG54_RS23265	COG0824	Thioesterase
RG54_RS23270	COG0811	peptide transport
RG54_RS23275	COG0848	biopolymer transport protein
RG54_RS23280	COG3064	Membrane
RG54_RS23290	COG2885	chlorophyll binding
RG54_RS23295	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
RG54_RS23345	COG3201	nicotinamide mononucleotide transporter
RG54_RS23350	COG1230	cation diffusion facilitator family transporter
RG54_RS23365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RG54_RS23375	COG2017	converts alpha-aldose to the beta-anomer
RG54_RS23385	COG1085	galactose-1-phosphate uridylyltransferase
RG54_RS23390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RG54_RS23395	COG1119	ATPase activity
RG54_RS23400	COG3585	molybdate ion transport
RG54_RS23400	COG2005	Transcriptional regulator
RG54_RS23415	COG0725	ABC transporter, periplasmic molybdate-binding protein
RG54_RS23420	COG4149	molybdate abc transporter
RG54_RS23430	COG0561	phosphatase activity
RG54_RS23440	COG0583	DNA-binding transcription factor activity
RG54_RS23445	COG2828	Protein conserved in bacteria
RG54_RS23450	COG0471	metal ion transport
RG54_RS23455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RG54_RS23460	COG4677	pectinesterase activity
RG54_RS23470	COG1881	PFAM PEBP family protein
RG54_RS23475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RG54_RS23490	COG2226	methyltransferase
RG54_RS23495	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RG54_RS23505	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RG54_RS23515	COG0521	Mo-molybdopterin cofactor biosynthetic process
RG54_RS23525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RG54_RS23530	COG0314	molybdopterin synthase activity
RG54_RS23535	COG0670	Belongs to the BI1 family
RG54_RS23540	COG0670	Belongs to the BI1 family
RG54_RS23545	COG0392	lysyltransferase activity
RG54_RS23550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RG54_RS23555	COG3568	Endonuclease Exonuclease Phosphatase
RG54_RS23565	COG0842	Transport permease protein
RG54_RS23570	COG0842	Transport permease protein
RG54_RS23575	COG1131	(ABC) transporter
RG54_RS23585	COG1309	transcriptional regulator
RG54_RS23590	COG0513	Belongs to the DEAD box helicase family
RG54_RS23595	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
RG54_RS23605	COG1199	ATP-dependent helicase activity
RG54_RS23610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RG54_RS23615	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RG54_RS23625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RG54_RS23635	COG4774	siderophore transport
RG54_RS23650	COG0668	transmembrane transport
RG54_RS23660	COG1126	abc transporter atp-binding protein
RG54_RS23665	COG0765	amino acid transport
RG54_RS23670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG54_RS23695	COG5006	permease, DMT superfamily
RG54_RS23700	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RG54_RS23705	COG2194	sulfuric ester hydrolase activity
RG54_RS23715	COG1321	iron dependent repressor
RG54_RS23720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RG54_RS23725	COG1376	ErfK ybiS ycfS ynhG family protein
RG54_RS23730	COG0488	(ABC) transporter
RG54_RS23745	COG0561	phosphatase activity
RG54_RS23750	COG1882	Formate acetyltransferase
RG54_RS23755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RG54_RS23760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RG54_RS23765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RG54_RS23770	COG0303	'Molybdopterin
RG54_RS23775	COG1446	asparaginase
RG54_RS23800	COG2200	EAL domain
RG54_RS23805	COG2199	diguanylate cyclase activity
RG54_RS23820	COG2133	pyrroloquinoline quinone binding
RG54_RS23825	COG0625	glutathione transferase activity
RG54_RS23830	COG1686	Belongs to the peptidase S11 family
RG54_RS23835	COG1349	DNA-binding transcription factor activity
RG54_RS23840	COG0671	phosphoesterase, PA-phosphatase related
RG54_RS23845	COG2814	Major facilitator Superfamily
RG54_RS23855	COG0561	phosphatase activity
RG54_RS23860	COG0738	Major facilitator superfamily
RG54_RS23865	COG3226	Transcriptional regulator
RG54_RS23880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RG54_RS23890	COG0778	Nitroreductase
RG54_RS23910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RG54_RS23915	COG3842	ATPase activity
RG54_RS23920	COG1176	ABC-type spermidine putrescine transport system, permease component I
RG54_RS23925	COG1177	transmembrane transport
RG54_RS23945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG54_RS23950	COG4160	amino acid transport
RG54_RS23955	COG4215	(ABC) transporter
RG54_RS23960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG54_RS23965	COG1126	abc transporter atp-binding protein
RG54_RS23980	COG3023	N-Acetylmuramoyl-L-alanine amidase
RG54_RS23985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RG54_RS23990	COG0702	epimerase
RG54_RS23995	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
RG54_RS24000	COG0028	Belongs to the TPP enzyme family
RG54_RS24005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG54_RS24015	COG2431	L-lysine efflux transmembrane transporter activity
RG54_RS24035	COG3593	DNA synthesis involved in DNA repair
RG54_RS24040	COG2990	Protein conserved in bacteria
RG54_RS24045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG54_RS24050	COG0577	efflux transmembrane transporter activity
RG54_RS24050	COG1136	(ABC) transporter
RG54_RS24055	COG1278	Cold shock
RG54_RS24065	COG0542	response to heat
RG54_RS24095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RG54_RS24100	COG4988	ABC transporter
RG54_RS24105	COG0492	ferredoxin-NADP+ reductase activity
RG54_RS24115	COG1522	sequence-specific DNA binding
RG54_RS24130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RG54_RS24140	COG0243	molybdopterin cofactor binding
RG54_RS24145	COG0437	4 iron, 4 sulfur cluster binding
RG54_RS24150	COG3302	dmso reductase anchor subunit
RG54_RS24155	COG1335	isochorismatase
RG54_RS24165	COG0531	amino acid
RG54_RS24170	COG0583	DNA-binding transcription factor activity
RG54_RS24175	COG2249	NAD(P)H dehydrogenase (quinone) activity
RG54_RS24180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RG54_RS24190	COG1944	ATP diphosphatase activity
RG54_RS24195	COG2323	membrane
RG54_RS24210	COG0501	Belongs to the peptidase M48B family
RG54_RS24220	COG0539	negative regulation of cytoplasmic translation
RG54_RS24230	COG2333	competence protein COMEC
RG54_RS24230	COG0658	competence protein
RG54_RS24235	COG1132	(ABC) transporter
RG54_RS24245	COG3214	Protein conserved in bacteria
RG54_RS24260	COG3173	Aminoglycoside phosphotransferase
RG54_RS24265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RG54_RS24270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RG54_RS24280	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
RG54_RS24290	COG2989	Protein conserved in bacteria
RG54_RS24300	COG3108	Peptidase M15
RG54_RS24305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RG54_RS24310	COG1448	Aminotransferase
RG54_RS24335	COG0308	aminopeptidase N
RG54_RS24350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RG54_RS24360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RG54_RS24365	COG0431	NADPH-dependent FMN reductase
RG54_RS24375	COG3539	Fimbrial protein
RG54_RS24380	COG3121	Chaperone
RG54_RS24385	COG3188	usher protein
RG54_RS24390	COG3539	Fimbrial protein
RG54_RS24395	COG3539	Fimbrial protein
RG54_RS24400	COG3539	Fimbrial protein
RG54_RS24405	COG3121	Chaperone
RG54_RS24420	COG3217	Mosc domain protein beta barrel domain protein
RG54_RS24420	COG0633	Ferredoxin
RG54_RS24430	COG0488	(ABC) transporter
RG54_RS24435	COG2995	paraquat-inducible protein a
RG54_RS24440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RG54_RS24440	COG3008	intermembrane lipid transfer
RG54_RS24445	COG3009	Protein conserved in bacteria
RG54_RS24450	COG3130	regulation of translation
RG54_RS24460	COG1067	ATP-dependent peptidase activity
RG54_RS24485	COG3070	regulator of competence-specific genes
RG54_RS24490	COG1289	transmembrane transporter activity
RG54_RS24495	COG3304	Inner membrane component domain
RG54_RS24500	COG0210	DNA helicase
RG54_RS24520	COG1832	CoA-binding protein
RG54_RS24535	COG1254	Belongs to the acylphosphatase family
RG54_RS24540	COG2920	part of a sulfur-relay system
RG54_RS24545	COG0670	Belongs to the BI1 family
RG54_RS24555	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RG54_RS24560	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
RG54_RS24565	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
RG54_RS24570	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RG54_RS24575	COG1999	signal sequence binding
RG54_RS24580	COG1773	rubredoxin
RG54_RS24585	COG1271	oxidase subunit
RG54_RS24590	COG1294	oxidase, subunit
RG54_RS24605	COG3206	protein involved in exopolysaccharide biosynthesis
RG54_RS24605	COG0489	protein tyrosine kinase activity
RG54_RS24610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RG54_RS24615	COG1596	polysaccharide export
RG54_RS24620	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG54_RS24640	COG1278	Cold shock
RG54_RS24645	COG1278	Cold shock
RG54_RS24665	COG0348	domain, Protein
RG54_RS24670	COG2205	protein histidine kinase activity
RG54_RS24670	COG2198	Histidine kinase
RG54_RS24670	COG0784	Response regulator, receiver
RG54_RS24675	COG1879	ABC-type sugar transport system periplasmic component
RG54_RS24680	COG0745	RESPONSE REGULATOR receiver
RG54_RS24685	COG3005	denitrification pathway
RG54_RS24690	COG0243	molybdopterin cofactor binding
RG54_RS24740	COG3729	General stress protein
RG54_RS24750	COG2233	PERMEase
RG54_RS24785	COG1309	transcriptional regulator
RG54_RS24790	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RG54_RS24790	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RG54_RS24790	COG0506	proline dehydrogenase activity
RG54_RS24805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RG54_RS24820	COG2822	iron ion transport
RG54_RS24835	COG1702	phosphate starvation-inducible protein PhoH
RG54_RS24865	COG3381	protein complex oligomerization
RG54_RS24875	COG1462	curli production assembly transport component CsgG
RG54_RS24890	COG2197	response regulator
RG54_RS24925	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RG54_RS24930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RG54_RS24945	COG2943	transferase activity, transferring hexosyl groups
RG54_RS24950	COG5645	(Lipo)protein
RG54_RS24970	COG1560	Kdo2-lipid A biosynthetic process
RG54_RS24980	COG2353	YceI-like domain
RG54_RS24985	COG3038	cytochrome b561
RG54_RS25025	COG2999	glutathione oxidoreductase activity
RG54_RS25035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RG54_RS25045	COG0673	inositol 2-dehydrogenase activity
RG54_RS25050	COG0728	peptidoglycan biosynthetic process
RG54_RS25055	COG3418	PFAM FlgN family protein
RG54_RS25060	COG2747	anti-sigma28 factor FlgM
RG54_RS25065	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
RG54_RS25070	COG1815	bacterial-type flagellum-dependent cell motility
RG54_RS25075	COG1558	bacterial-type flagellum-dependent cell motility
RG54_RS25080	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RG54_RS25085	COG1749	Flagellar hook protein flgE
RG54_RS25090	COG4787	bacterial-type flagellum-dependent cell motility
RG54_RS25095	COG4786	Flagellar basal body rod
RG54_RS25110	COG1705	Flagellar rod assembly protein muramidase FlgJ
RG54_RS25110	COG3951	Flagellar rod assembly protein muramidase FlgJ
RG54_RS25115	COG1256	bacterial-type flagellum assembly
RG54_RS25120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RG54_RS25125	COG1530	ribonuclease E activity
RG54_RS25135	COG0564	pseudouridine synthase activity
RG54_RS25140	COG0424	maF-like protein
RG54_RS25145	COG1399	metal-binding, possibly nucleic acid-binding protein
RG54_RS25165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RG54_RS25170	COG1028	Short-chain dehydrogenase reductase Sdr
RG54_RS25180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RG54_RS25185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RG54_RS25190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RG54_RS25200	COG0470	DNA polymerase III
RG54_RS25205	COG0084	hydrolase, TatD family'
RG54_RS25210	COG1263	PTS System
RG54_RS25210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG54_RS25215	COG4773	Receptor
RG54_RS25220	COG0537	adenosine 5'-monophosphoramidase activity
RG54_RS25225	COG5633	Lipoprotein
RG54_RS25230	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
RG54_RS25255	COG1252	NADH dehydrogenase
RG54_RS25265	COG3134	Outer membrane lipoprotein
RG54_RS25270	COG1309	transcriptional regulator
RG54_RS25280	COG1388	LysM domain
RG54_RS25280	COG1376	ErfK ybiS ycfS ynhG family protein
RG54_RS25285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RG54_RS25290	COG4763	Acyl-transferase
RG54_RS25295	COG4591	ABC-type transport system involved in lipoprotein release permease component
RG54_RS25300	COG1136	(ABC) transporter
RG54_RS25305	COG4591	ABC-type transport system involved in lipoprotein release permease component
RG54_RS25315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RG54_RS25320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RG54_RS25330	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RG54_RS25335	COG1177	transmembrane transport
RG54_RS25340	COG0582	viral genome integration into host DNA
RG54_RS25350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG54_RS25390	COG4197	protein conserved in bacteria, prophage-related
RG54_RS25440	COG1403	HNH endonuclease
RG54_RS25445	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
RG54_RS25450	COG0484	heat shock protein binding
RG54_RS25510	COG3772	lysozyme
RG54_RS25520	COG3038	cytochrome b561
RG54_RS25535	COG4220	transposase activity
RG54_RS25605	COG1196	nuclear chromosome segregation
RG54_RS25645	COG5301	cellulose 1,4-beta-cellobiosidase activity
RG54_RS25670	COG3842	ATPase activity
RG54_RS25685	COG2850	peptidyl-arginine hydroxylation
RG54_RS25690	COG2205	protein histidine kinase activity
RG54_RS25700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RG54_RS25720	COG1187	pseudouridine synthase activity
RG54_RS25725	COG0538	isocitrate dehydrogenase activity
RG54_RS25740	COG5562	phage envelope protein
RG54_RS25745	COG0789	Transcriptional regulator
RG54_RS25750	COG2200	EAL domain
RG54_RS25775	COG2200	EAL domain
RG54_RS25835	COG2894	cell division
RG54_RS25865	COG0179	Fumarylacetoacetate (FAA) hydrolase
RG54_RS25885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RG54_RS25890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RG54_RS26055	COG3468	outer membrane autotransporter barrel domain protein
RG54_RS26065	COG3468	outer membrane autotransporter barrel domain protein
RG54_RS26335	COG1454	alcohol dehydrogenase
RG54_RS26335	COG1012	belongs to the aldehyde dehydrogenase family
RG54_RS26355	COG0601	transmembrane transport
RG54_RS26560	COG4166	transmembrane transport
RG54_RS26565	COG4166	transmembrane transport
RG54_RS26575	COG4166	transmembrane transport
RG54_RS26585	COG0531	amino acid
RG54_RS26595	COG0531	amino acid
RG54_RS26650	COG1842	Phage shock protein A
RG54_RS26800	COG0589	response to stress
RG54_RS26820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RG54_RS26855	COG1473	amidohydrolase
RG54_RS26945	COG0582	viral genome integration into host DNA
RG54_RS27115	COG1475	DNA binding