locus-tag	class	description
IC756_RS00030	COG4695	Portal protein
IC756_RS00120	COG5301	cellulose 1,4-beta-cellobiosidase activity
IC756_RS00185	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC756_RS00205	COG3152	Membrane
IC756_RS00210	COG3691	Protein conserved in bacteria
IC756_RS00215	COG0589	response to stress
IC756_RS00225	COG1494	fructose-1,6-bisphosphatase
IC756_RS00235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IC756_RS00260	COG1575	Belongs to the MenA family. Type 1 subfamily
IC756_RS00275	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IC756_RS00280	COG1609	Transcriptional regulator
IC756_RS00285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC756_RS00295	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IC756_RS00305	COG0626	cystathionine gamma-synthase activity
IC756_RS00310	COG0527	aspartate kinase activity
IC756_RS00310	COG0460	homoserine dehydrogenase
IC756_RS00320	COG0737	Belongs to the 5'-nucleotidase family
IC756_RS00325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC756_RS00335	COG0697	spore germination
IC756_RS00340	COG3738	Protein conserved in bacteria
IC756_RS00345	COG0371	Dehydrogenase
IC756_RS00350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC756_RS00355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS00355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS00355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC756_RS00360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC756_RS00365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC756_RS00370	COG1882	Formate acetyltransferase
IC756_RS00375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IC756_RS00380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC756_RS00385	COG2207	Transcriptional regulator
IC756_RS00390	COG2194	sulfuric ester hydrolase activity
IC756_RS00405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IC756_RS00420	COG0583	DNA-binding transcription factor activity
IC756_RS00430	COG1309	transcriptional regulator
IC756_RS00445	COG4206	TonB-dependent receptor
IC756_RS00480	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IC756_RS00480	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IC756_RS00515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IC756_RS00520	COG0250	Participates in transcription elongation, termination and antitermination
IC756_RS00560	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IC756_RS00570	COG2104	thiamine diphosphate biosynthetic process
IC756_RS00575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IC756_RS00610	COG3068	Protein conserved in bacteria
IC756_RS00625	COG3678	ATP-independent chaperone mediated protein folding
IC756_RS00630	COG4191	Histidine kinase
IC756_RS00635	COG2204	response regulator
IC756_RS00640	COG0151	Belongs to the GarS family
IC756_RS00670	COG0456	acetyltransferase
IC756_RS00680	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC756_RS00685	COG2224	Isocitrate lyase
IC756_RS00700	COG1414	Transcriptional regulator
IC756_RS00705	COG0646	methionine synthase
IC756_RS00705	COG1410	methionine synthase
IC756_RS00710	COG1283	sodium-dependent phosphate transmembrane transporter activity
IC756_RS00755	COG1187	pseudouridine synthase activity
IC756_RS00765	COG0527	aspartate kinase activity
IC756_RS00790	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC756_RS00805	COG3833	ABC-type maltose transport systems, permease component
IC756_RS00810	COG1175	transmembrane transport
IC756_RS00815	COG2182	Extracellular solute-binding protein
IC756_RS00820	COG3842	ATPase activity
IC756_RS00835	COG1357	PFAM Pentapeptide repeats (8 copies)
IC756_RS00855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IC756_RS00865	COG0534	Mate efflux family protein
IC756_RS00870	COG3237	CsbD-like
IC756_RS00875	COG0735	belongs to the Fur family
IC756_RS00885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC756_RS00895	COG0604	alcohol dehydrogenase
IC756_RS00900	COG0305	Participates in initiation and elongation during chromosome replication
IC756_RS00905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC756_RS00910	COG1448	Aminotransferase
IC756_RS00920	COG3700	Belongs to the class B bacterial acid phosphatase family
IC756_RS00925	COG0432	Pfam Uncharacterised protein family UPF0047
IC756_RS00930	COG2315	Protein conserved in bacteria
IC756_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IC756_RS00940	COG0629	single-stranded DNA binding
IC756_RS00950	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC756_RS00955	COG2207	Transcriptional regulator
IC756_RS00960	COG0789	Transcriptional regulator
IC756_RS00965	COG2252	PERMEase
IC756_RS00970	COG0025	NhaP-type Na H and K H
IC756_RS00975	COG1357	PFAM Pentapeptide repeats (8 copies)
IC756_RS00985	COG3162	membrane
IC756_RS00990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC756_RS01000	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IC756_RS01005	COG0437	4 iron, 4 sulfur cluster binding
IC756_RS01010	COG3301	Polysulphide reductase, NrfD
IC756_RS01015	COG1138	Cytochrome C-type biogenesis protein
IC756_RS01025	COG4235	cytochrome complex assembly
IC756_RS01030	COG1301	dicarboxylic acid transport
IC756_RS01035	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IC756_RS01050	COG1289	transmembrane transporter activity
IC756_RS01055	COG1566	PFAM secretion protein HlyD family protein
IC756_RS01065	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IC756_RS01070	COG0698	ribose 5-phosphate isomerase
IC756_RS01080	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IC756_RS01085	COG0456	acetyltransferase
IC756_RS01095	COG3454	Phosphonate metabolism
IC756_RS01100	COG4778	phosphonate C-P lyase system protein PhnL
IC756_RS01105	COG4107	phosphonate C-P lyase system protein PhnK
IC756_RS01110	COG3627	carbon phosphorus lyase activity
IC756_RS01115	COG3626	phosphonate metabolism
IC756_RS01120	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IC756_RS01125	COG3624	Phosphonate C-P lyase system protein PhnG
IC756_RS01130	COG2188	Transcriptional regulator
IC756_RS01135	COG3639	organic phosphonate transmembrane transporter activity
IC756_RS01140	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IC756_RS01150	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IC756_RS01155	COG2824	Alkylphosphonate utilization operon protein PhnA
IC756_RS01160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IC756_RS01170	COG0477	Major facilitator Superfamily
IC756_RS01180	COG0642	Histidine kinase
IC756_RS01185	COG0745	RESPONSE REGULATOR receiver
IC756_RS01190	COG2194	sulfuric ester hydrolase activity
IC756_RS01195	COG0531	amino acid
IC756_RS01200	COG2207	Transcriptional regulator
IC756_RS01205	COG1982	Orn Lys Arg decarboxylase major
IC756_RS01210	COG2169	Transcriptional regulator
IC756_RS01215	COG1486	melibiose metabolic process
IC756_RS01220	COG2211	Major facilitator Superfamily
IC756_RS01225	COG3647	Membrane
IC756_RS01230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC756_RS01230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC756_RS01235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IC756_RS01240	COG4565	transcriptional regulatory protein
IC756_RS01245	COG3290	protein histidine kinase activity
IC756_RS01250	COG3592	Divergent 4Fe-4S mono-cluster
IC756_RS01255	COG2388	GCN5-related N-acetyl-transferase
IC756_RS01270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IC756_RS01275	COG3104	oligopeptide transport
IC756_RS01280	COG1982	Orn Lys Arg decarboxylase major
IC756_RS01285	COG0531	amino acid
IC756_RS01290	COG3710	Transcriptional regulator
IC756_RS01300	COG1309	transcriptional regulator
IC756_RS01305	COG4232	protein-disulfide reductase activity
IC756_RS01315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IC756_RS01320	COG1027	Aspartate ammonia-lyase
IC756_RS01325	COG3030	protein affecting phage T7 exclusion by the F plasmid
IC756_RS01330	COG0531	amino acid
IC756_RS01355	COG1509	lysine 2,3-aminomutase activity
IC756_RS01365	COG5510	response to toxic substance
IC756_RS01370	COG5510	response to toxic substance
IC756_RS01375	COG2076	Multidrug Resistance protein
IC756_RS01380	COG3040	lipid binding
IC756_RS01385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC756_RS01400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC756_RS01405	COG1053	succinate dehydrogenase
IC756_RS01415	COG0531	amino acid
IC756_RS01420	COG3264	Mechanosensitive ion channel
IC756_RS01420	COG1511	domain protein
IC756_RS01460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC756_RS01465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC756_RS01465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC756_RS01470	COG0802	atpase or kinase
IC756_RS01475	COG0860	N-Acetylmuramoyl-L-alanine amidase
IC756_RS01495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC756_RS01500	COG0330	HflC and HflK could
IC756_RS01505	COG0330	HflC and HflK could
IC756_RS01510	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IC756_RS01525	COG0557	exoribonuclease II activity
IC756_RS01530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC756_RS01535	COG3789	protein conserved in bacteria
IC756_RS01540	COG1842	Phage shock protein A
IC756_RS01550	COG3766	membrane
IC756_RS01555	COG5463	Belongs to the UPF0441 family
IC756_RS01560	COG0754	glutathionylspermidine amidase activity
IC756_RS01565	COG1960	acyl-CoA dehydrogenase activity
IC756_RS01575	COG3650	response to hydrogen peroxide
IC756_RS01580	COG1073	alpha beta
IC756_RS01595	COG3037	sugar-specific permease SgaT UlaA
IC756_RS01600	COG3414	Phosphotransferase system galactitol-specific IIB component
IC756_RS01605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS01640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IC756_RS01665	COG0675	Transposase, IS605 OrfB family
IC756_RS01675	COG3061	Opacity-associated protein A
IC756_RS01680	COG0545	Peptidyl-prolyl cis-trans isomerase
IC756_RS01685	COG1113	amino acid transport
IC756_RS01705	COG0697	spore germination
IC756_RS01710	COG0702	epimerase
IC756_RS01715	COG1733	regulation of RNA biosynthetic process
IC756_RS01720	COG0737	Belongs to the 5'-nucleotidase family
IC756_RS01725	COG1218	3'(2'),5'-bisphosphate nucleotidase
IC756_RS01735	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IC756_RS01745	COG1253	flavin adenine dinucleotide binding
IC756_RS01755	COG0729	surface antigen
IC756_RS01760	COG2911	Protein conserved in bacteria
IC756_RS01765	COG2105	PFAM AIG2 family protein
IC756_RS01770	COG2336	PFAM SpoVT AbrB
IC756_RS01775	COG2337	Toxic component of a toxin-antitoxin (TA) module
IC756_RS01780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC756_RS01785	COG1879	ABC-type sugar transport system periplasmic component
IC756_RS01790	COG1129	ABC transporter
IC756_RS01795	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC756_RS01800	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC756_RS01810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC756_RS01820	COG0312	modulator of DNA gyrase
IC756_RS01825	COG3783	Cytochrome b(562)
IC756_RS01830	COG3077	Addiction module antitoxin, RelB DinJ family
IC756_RS01835	COG2026	Addiction module toxin, RelE StbE family
IC756_RS01840	COG0602	queuosine metabolic process
IC756_RS01845	COG1328	CTP reductase activity
IC756_RS01850	COG0366	Alpha amylase catalytic
IC756_RS01855	COG1263	PTS System
IC756_RS01855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS01860	COG1609	Transcriptional regulator
IC756_RS01870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IC756_RS01875	COG0251	oxidation-reduction process
IC756_RS01895	COG0251	oxidation-reduction process
IC756_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS01905	COG1309	transcriptional regulator
IC756_RS01910	COG2731	YhcH YjgK YiaL family protein
IC756_RS01925	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IC756_RS01930	COG0456	acetyltransferase
IC756_RS01935	COG4269	membrane
IC756_RS01940	COG0525	valine-tRNA ligase activity
IC756_RS01945	COG2927	DNA polymerase III (CHI subunit)
IC756_RS01955	COG0795	lipopolysaccharide-transporting ATPase activity
IC756_RS01960	COG0795	lipopolysaccharide-transporting ATPase activity
IC756_RS01965	COG0433	COG0433 Predicted ATPase
IC756_RS01970	COG1064	alcohol dehydrogenase
IC756_RS01980	COG0582	viral genome integration into host DNA
IC756_RS02060	COG0328	RNA-DNA hybrid ribonuclease activity
IC756_RS02065	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IC756_RS02065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC756_RS02080	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IC756_RS02095	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC756_RS02120	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IC756_RS02125	COG0582	viral genome integration into host DNA
IC756_RS02130	COG4974	Belongs to the 'phage' integrase family
IC756_RS02135	COG3539	Fimbrial protein
IC756_RS02140	COG3539	Fimbrial protein
IC756_RS02145	COG3121	Chaperone
IC756_RS02150	COG3188	usher protein
IC756_RS02155	COG3539	Fimbrial protein
IC756_RS02160	COG3539	Fimbrial protein
IC756_RS02165	COG3539	Fimbrial protein
IC756_RS02170	COG2610	gluconate transmembrane transporter activity
IC756_RS02180	COG0246	Mannitol dehydrogenase
IC756_RS02185	COG2186	Transcriptional regulator
IC756_RS02205	COG0583	DNA-binding transcription factor activity
IC756_RS02210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IC756_RS02215	COG0700	Nucleoside recognition
IC756_RS02220	COG3366	ferrous iron transmembrane transporter activity
IC756_RS02230	COG1388	LysM domain
IC756_RS02230	COG1470	cell adhesion involved in biofilm formation
IC756_RS02235	COG0477	Major facilitator Superfamily
IC756_RS02240	COG3204	pilus organization
IC756_RS02255	COG1924	4 iron, 4 sulfur cluster binding
IC756_RS02260	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
IC756_RS02265	COG2733	membrane
IC756_RS02270	COG2814	Major facilitator Superfamily
IC756_RS02280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC756_RS02285	COG5457	Domain of unknown function (DUF1127)
IC756_RS02305	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IC756_RS02325	COG0523	cobalamin synthesis protein
IC756_RS02330	COG2879	small protein
IC756_RS02335	COG1966	Carbon starvation protein
IC756_RS02340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC756_RS02345	COG2368	4-hydroxyphenylacetate
IC756_RS02350	COG1234	tRNA 3'-trailer cleavage
IC756_RS02370	COG3971	2-oxopent-4-enoate hydratase activity
IC756_RS02380	COG3384	dioxygenase
IC756_RS02385	COG1012	belongs to the aldehyde dehydrogenase family
IC756_RS02390	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC756_RS02395	COG1846	Transcriptional regulator
IC756_RS02400	COG0840	transmembrane signaling receptor activity
IC756_RS02405	COG2271	Major facilitator Superfamily
IC756_RS02410	COG1802	Transcriptional regulator
IC756_RS02415	COG1063	alcohol dehydrogenase
IC756_RS02430	COG1484	DNA-dependent DNA replication
IC756_RS02445	COG2966	Psort location CytoplasmicMembrane, score
IC756_RS02450	COG2197	response regulator
IC756_RS02455	COG2197	response regulator
IC756_RS02460	COG4114	ferric iron reductase
IC756_RS02490	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IC756_RS02495	COG0456	acetyltransferase
IC756_RS02500	COG1011	Hydrolase
IC756_RS02510	COG2823	Periplasmic or secreted lipoprotein
IC756_RS02520	COG4667	esterase of the alpha-beta hydrolase superfamily
IC756_RS02525	COG0084	hydrolase, TatD family'
IC756_RS02530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IC756_RS02535	COG1328	CTP reductase activity
IC756_RS02570	COG3726	membrane protein affecting hemolysin expression
IC756_RS02575	COG0560	Phosphoserine phosphatase
IC756_RS02580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IC756_RS02585	COG1056	cytidyltransferase-related domain
IC756_RS02585	COG3172	ATPase kinase involved in NAD metabolism
IC756_RS02590	COG1902	pentaerythritol trinitrate reductase activity
IC756_RS02605	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS02615	COG0583	DNA-binding transcription factor activity
IC756_RS02620	COG0488	(ABC) transporter
IC756_RS02625	COG0741	lytic transglycosylase activity
IC756_RS02645	COG3708	Transcriptional regulator
IC756_RS02645	COG2207	Transcriptional regulator
IC756_RS02650	COG3045	CreA protein
IC756_RS02655	COG0745	RESPONSE REGULATOR receiver
IC756_RS02660	COG2205	protein histidine kinase activity
IC756_RS02665	COG4452	Inner membrane protein CreD
IC756_RS02670	COG0745	RESPONSE REGULATOR receiver
IC756_RS02680	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IC756_RS02690	COG0527	aspartate kinase activity
IC756_RS02690	COG0460	homoserine dehydrogenase
IC756_RS02700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC756_RS02715	COG1115	amino acid carrier protein
IC756_RS02725	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC756_RS02730	COG1584	GPR1 FUN34 yaaH family protein
IC756_RS02735	COG4735	regulation of single-species biofilm formation
IC756_RS02765	COG0583	DNA-binding transcription factor activity
IC756_RS02775	COG3188	usher protein
IC756_RS02780	COG3121	Chaperone
IC756_RS02805	COG0196	riboflavin kinase activity
IC756_RS02820	COG1047	Peptidyl-prolyl cis-trans
IC756_RS02840	COG0505	Belongs to the CarA family
IC756_RS02845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IC756_RS02895	COG0644	oxidoreductase
IC756_RS02900	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC756_RS02905	COG2271	Major facilitator Superfamily
IC756_RS02920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC756_RS02945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC756_RS02950	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IC756_RS02955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IC756_RS02960	COG1357	PFAM Pentapeptide repeats (8 copies)
IC756_RS02970	COG0564	pseudouridine synthase activity
IC756_RS02980	COG0417	DNA replication proofreading
IC756_RS02985	COG0235	Class ii aldolase
IC756_RS03000	COG4977	sequence-specific DNA binding
IC756_RS03005	COG0586	Pfam SNARE associated Golgi protein
IC756_RS03015	COG1178	ABC-type Fe3 transport system permease component
IC756_RS03020	COG4143	(ABC) transporter
IC756_RS03065	COG0583	DNA-binding transcription factor activity
IC756_RS03075	COG0028	Belongs to the TPP enzyme family
IC756_RS03080	COG0440	acetolactate synthase activity
IC756_RS03090	COG1609	Transcriptional regulator
IC756_RS03105	COG3116	cell division
IC756_RS03110	COG0768	penicillin binding
IC756_RS03115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC756_RS03120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC756_RS03135	COG0772	Belongs to the SEDS family
IC756_RS03150	COG1181	Belongs to the D-alanine--D-alanine ligase family
IC756_RS03155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC756_RS03160	COG0849	cell division
IC756_RS03165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC756_RS03185	COG0494	nUDIX hydrolase
IC756_RS03200	COG0237	dephospho-CoA kinase activity
IC756_RS03215	COG1459	type II secretion system
IC756_RS03220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC756_RS03225	COG4969	Belongs to the N-Me-Phe pilin family
IC756_RS03230	COG0157	Belongs to the NadC ModD family
IC756_RS03235	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC756_RS03240	COG3725	Membrane protein required for beta-lactamase induction
IC756_RS03250	COG2186	Transcriptional regulator
IC756_RS03255	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IC756_RS03260	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC756_RS03265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC756_RS03270	COG3064	Membrane
IC756_RS03275	COG1049	propionate catabolic process, 2-methylcitrate cycle
IC756_RS03300	COG2132	Multicopper oxidase
IC756_RS03305	COG4993	Dehydrogenase
IC756_RS03310	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IC756_RS03315	COG0288	reversible hydration of carbon dioxide
IC756_RS03320	COG1131	(ABC) transporter
IC756_RS03325	COG0842	Transport permease protein
IC756_RS03330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS03335	COG0726	polysaccharide deacetylase
IC756_RS03345	COG5464	transposase or invertase
IC756_RS03360	COG3539	Fimbrial protein
IC756_RS03365	COG3539	Fimbrial protein
IC756_RS03370	COG3539	Fimbrial protein
IC756_RS03375	COG3188	usher protein
IC756_RS03380	COG3121	Chaperone
IC756_RS03385	COG3539	Fimbrial protein
IC756_RS03390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC756_RS03395	COG0617	tRNA 3'-terminal CCA addition
IC756_RS03400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC756_RS03405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC756_RS03415	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IC756_RS03420	COG1643	Atp-dependent helicase
IC756_RS03425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC756_RS03430	COG4774	siderophore transport
IC756_RS03435	COG1120	ATPase activity
IC756_RS03440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IC756_RS03445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC756_RS03470	COG2860	membrane
IC756_RS03475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IC756_RS03490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC756_RS03495	COG3835	regulator
IC756_RS03515	COG0024	Methionine aminopeptidase
IC756_RS03540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IC756_RS03545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC756_RS03550	COG0575	Belongs to the CDS family
IC756_RS03555	COG0750	zinc metalloprotease
IC756_RS03565	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IC756_RS03570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC756_RS03595	COG0587	DNA-directed DNA polymerase activity
IC756_RS03605	COG1982	Orn Lys Arg decarboxylase major
IC756_RS03610	COG0346	lactoylglutathione lyase activity
IC756_RS03620	COG4568	rho-dependent transcription termination
IC756_RS03630	COG4681	YaeQ
IC756_RS03635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IC756_RS03640	COG3015	lipoprotein NlpE involved in copper resistance
IC756_RS03645	COG0791	NLP P60 protein
IC756_RS03655	COG1720	tRNA m6t6A37 methyltransferase activity
IC756_RS03665	COG1464	Belongs to the NlpA lipoprotein family
IC756_RS03670	COG2011	ABC-type metal ion transport system permease component
IC756_RS03675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC756_RS03680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IC756_RS03715	COG0656	L-ascorbic acid biosynthetic process
IC756_RS03720	COG0583	DNA-binding transcription factor activity
IC756_RS03730	COG2226	methyltransferase
IC756_RS03735	COG1388	LysM domain
IC756_RS03735	COG0741	lytic transglycosylase activity
IC756_RS03745	COG2226	methyltransferase
IC756_RS03755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC756_RS03860	COG2826	transposase and inactivated derivatives, IS30 family
IC756_RS03890	COG5433	transposase activity
IC756_RS03905	COG5433	transposase activity
IC756_RS03920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC756_RS03930	COG1960	acyl-CoA dehydrogenase activity
IC756_RS03940	COG0121	glutamine amidotransferase
IC756_RS03945	COG3034	peptidoglycan biosynthetic process
IC756_RS03950	COG0791	NLP P60 protein
IC756_RS03955	COG1943	Transposase
IC756_RS03975	COG2161	toxin-antitoxin pair type II binding
IC756_RS03985	COG0454	-acetyltransferase
IC756_RS03990	COG1690	Belongs to the RtcB family
IC756_RS03995	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IC756_RS04010	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC756_RS04030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IC756_RS04055	COG0583	DNA-binding transcription factor activity
IC756_RS04070	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IC756_RS04075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC756_RS04080	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IC756_RS04095	COG2080	2 iron, 2 sulfur cluster binding
IC756_RS04100	COG3477	response to acidic pH
IC756_RS04105	COG0727	PFAM Uncharacterised protein family (UPF0153)
IC756_RS04110	COG3121	Chaperone
IC756_RS04160	COG1902	pentaerythritol trinitrate reductase activity
IC756_RS04165	COG1073	alpha beta
IC756_RS04170	COG0583	DNA-binding transcription factor activity
IC756_RS04180	COG0667	Aldo Keto reductase
IC756_RS04185	COG0656	L-ascorbic acid biosynthetic process
IC756_RS04190	COG1388	LysM domain
IC756_RS04195	COG2207	Transcriptional regulator
IC756_RS04195	COG3708	Transcriptional regulator
IC756_RS04200	COG0656	L-ascorbic acid biosynthetic process
IC756_RS04205	COG3059	membrane
IC756_RS04215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC756_RS04220	COG2207	Transcriptional regulator
IC756_RS04225	COG0247	lactate metabolic process
IC756_RS04230	COG1139	Iron-sulfur cluster binding protein
IC756_RS04235	COG1556	Lactate utilization protein
IC756_RS04260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC756_RS04265	COG2200	EAL domain
IC756_RS04265	COG2771	luxR family
IC756_RS04270	COG0583	DNA-binding transcription factor activity
IC756_RS04280	COG0666	response to abiotic stimulus
IC756_RS04290	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IC756_RS04295	COG1304	FMN binding
IC756_RS04300	COG0549	Belongs to the carbamate kinase family
IC756_RS04305	COG0402	S-adenosylhomocysteine deaminase activity
IC756_RS04315	COG1064	alcohol dehydrogenase
IC756_RS04330	COG1280	lysine exporter protein (LysE YggA)
IC756_RS04340	COG3829	transcription factor binding
IC756_RS04345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IC756_RS04355	COG0372	Belongs to the citrate synthase family
IC756_RS04360	COG2079	MmgE PrpD family protein
IC756_RS04365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC756_RS04370	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC756_RS04375	COG0402	S-adenosylhomocysteine deaminase activity
IC756_RS04380	COG0583	DNA-binding transcription factor activity
IC756_RS04385	COG0288	reversible hydration of carbon dioxide
IC756_RS04395	COG2807	transmembrane transport
IC756_RS04400	COG0110	maltose O-acetyltransferase activity
IC756_RS04405	COG2223	nitrite transmembrane transporter activity
IC756_RS04415	COG1609	Transcriptional regulator
IC756_RS04420	COG1414	Transcriptional regulator
IC756_RS04455	COG2814	Major facilitator Superfamily
IC756_RS04460	COG3122	Protein conserved in bacteria
IC756_RS04490	COG1215	transferase activity, transferring glycosyl groups
IC756_RS04495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IC756_RS04500	COG4521	taurine ABC transporter
IC756_RS04505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC756_RS04510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC756_RS04515	COG2175	clavaminate synthase activity
IC756_RS04520	COG0113	porphobilinogen synthase activity
IC756_RS04525	COG3468	outer membrane autotransporter barrel domain protein
IC756_RS04530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC756_RS04535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC756_RS04540	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC756_RS04560	COG1181	Belongs to the D-alanine--D-alanine ligase family
IC756_RS04575	COG1785	Belongs to the alkaline phosphatase family
IC756_RS04585	COG3706	GGDEF domain
IC756_RS04590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IC756_RS04610	COG4126	flavin adenine dinucleotide binding
IC756_RS04635	COG1940	carbohydrate kinase activity
IC756_RS04640	COG2814	Major facilitator Superfamily
IC756_RS04645	COG0419	ATPase involved in DNA repair
IC756_RS04650	COG0420	3'-5' exonuclease activity
IC756_RS04655	COG0745	RESPONSE REGULATOR receiver
IC756_RS04660	COG5002	protein histidine kinase activity
IC756_RS04665	COG1114	Component of the transport system for branched-chain amino acids
IC756_RS04670	COG1113	amino acid transport
IC756_RS04675	COG0366	Alpha amylase catalytic
IC756_RS04700	COG1862	Preprotein translocase
IC756_RS04705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC756_RS04710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC756_RS04715	COG1403	HNH endonuclease
IC756_RS04720	COG3248	Nucleoside-binding outer membrane protein
IC756_RS04725	COG4238	major outer membrane lipoprotein
IC756_RS04735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC756_RS04735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC756_RS04750	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC756_RS04755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC756_RS04765	COG0667	Aldo Keto reductase
IC756_RS04775	COG0142	geranyltranstransferase activity
IC756_RS04790	COG0693	protein deglycase activity
IC756_RS04795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IC756_RS04805	COG2814	Major facilitator Superfamily
IC756_RS04815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC756_RS04820	COG1845	cytochrome c oxidase, subunit III
IC756_RS04825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC756_RS04830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IC756_RS04835	COG2223	nitrite transmembrane transporter activity
IC756_RS04840	COG3056	Lipoprotein
IC756_RS04845	COG0271	Belongs to the BolA IbaG family
IC756_RS04865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IC756_RS04870	COG0776	regulation of translation
IC756_RS04875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC756_RS04880	COG1555	photosystem II stabilization
IC756_RS04885	COG0824	Thioesterase
IC756_RS04895	COG4533	DNA binding
IC756_RS04905	COG1522	sequence-specific DNA binding
IC756_RS04910	COG1132	(ABC) transporter
IC756_RS04915	COG1132	(ABC) transporter
IC756_RS04920	COG0347	Belongs to the P(II) protein family
IC756_RS04925	COG0004	ammonium transporteR
IC756_RS04930	COG1946	Acyl-CoA thioesterase
IC756_RS04935	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IC756_RS04940	COG3695	enzyme binding
IC756_RS04950	COG5507	3-demethylubiquinone-9 3-methyltransferase
IC756_RS04955	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC756_RS04965	COG0110	maltose O-acetyltransferase activity
IC756_RS04980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC756_RS04985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC756_RS04990	COG1309	transcriptional regulator
IC756_RS04995	COG1196	nuclear chromosome segregation
IC756_RS04995	COG3264	Mechanosensitive ion channel
IC756_RS05005	COG3923	Primosomal replication protein n
IC756_RS05010	COG2832	Protein of unknown function (DUF454)
IC756_RS05020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC756_RS05055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC756_RS05060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC756_RS05060	COG4651	solute:proton antiporter activity
IC756_RS05065	COG2223	nitrite transmembrane transporter activity
IC756_RS05070	COG0737	Belongs to the 5'-nucleotidase family
IC756_RS05075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC756_RS05080	COG3735	TraB family
IC756_RS05085	COG2217	Heavy metal translocating P-type atpase
IC756_RS05095	COG0531	amino acid
IC756_RS05120	COG0789	Transcriptional regulator
IC756_RS05145	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC756_RS05150	COG0330	HflC and HflK could
IC756_RS05155	COG4619	ABC transporter
IC756_RS05160	COG0390	transport system, permease component
IC756_RS05165	COG3118	belongs to the thioredoxin family
IC756_RS05170	COG0300	oxidoreductase activity
IC756_RS05175	COG2755	lipolytic protein G-D-S-L family
IC756_RS05180	COG4181	ATPase activity
IC756_RS05185	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC756_RS05195	COG0583	DNA-binding transcription factor activity
IC756_RS05205	COG1414	Transcriptional regulator
IC756_RS05210	COG3960	tartronate-semialdehyde synthase activity
IC756_RS05215	COG3622	Belongs to the hyi family
IC756_RS05220	COG2084	Dehydrogenase
IC756_RS05225	COG1953	Uracil, thiamine, allantoin
IC756_RS05235	COG2233	PERMEase
IC756_RS05240	COG1929	Belongs to the glycerate kinase type-1 family
IC756_RS05245	COG3257	ureidoglycine aminohydrolase activity
IC756_RS05250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IC756_RS05255	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IC756_RS05260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IC756_RS05265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IC756_RS05275	COG0549	Belongs to the carbamate kinase family
IC756_RS05280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC756_RS05285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IC756_RS05295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC756_RS05305	COG1988	membrane-bound metal-dependent
IC756_RS05310	COG2501	S4 domain
IC756_RS05320	COG3539	Fimbrial protein
IC756_RS05325	COG3121	Chaperone
IC756_RS05330	COG3188	usher protein
IC756_RS05335	COG3539	Fimbrial protein
IC756_RS05340	COG3539	Fimbrial protein
IC756_RS05345	COG2197	response regulator
IC756_RS05355	COG2207	Transcriptional regulator
IC756_RS05365	COG4783	chaperone-mediated protein folding
IC756_RS05370	COG1215	transferase activity, transferring glycosyl groups
IC756_RS05435	COG5002	protein histidine kinase activity
IC756_RS05440	COG0745	RESPONSE REGULATOR receiver
IC756_RS05445	COG1538	Outer membrane efflux protein
IC756_RS05450	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC756_RS05455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC756_RS05460	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC756_RS05465	COG1113	amino acid transport
IC756_RS05470	COG0668	transmembrane transport
IC756_RS05475	COG0778	Nitroreductase
IC756_RS05480	COG2315	Protein conserved in bacteria
IC756_RS05505	COG2977	Belongs to the P-Pant transferase superfamily
IC756_RS05510	COG4771	TonB-dependent receptor
IC756_RS05515	COG2382	esterase
IC756_RS05520	COG3251	PFAM MbtH domain protein
IC756_RS05525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC756_RS05525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC756_RS05530	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IC756_RS05535	COG1120	ATPase activity
IC756_RS05540	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC756_RS05545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC756_RS05555	COG4592	Periplasmic binding protein
IC756_RS05560	COG1169	isochorismate synthase
IC756_RS05565	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC756_RS05570	COG3433	isochorismatase activity
IC756_RS05570	COG1535	isochorismatase
IC756_RS05575	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS05585	COG1966	Carbon starvation protein
IC756_RS05590	COG2879	small protein
IC756_RS05595	COG0371	Dehydrogenase
IC756_RS05600	COG0436	Aminotransferase
IC756_RS05605	COG1475	DNA binding
IC756_RS05610	COG3969	phosphoadenosine phosphosulfate
IC756_RS05615	COG0583	DNA-binding transcription factor activity
IC756_RS05620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC756_RS05625	COG0450	alkyl hydroperoxide reductase
IC756_RS05630	COG3634	alkyl hydroperoxide reductase activity
IC756_RS05635	COG0589	response to stress
IC756_RS05640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC756_RS05645	COG3719	Belongs to the RNase T2 family
IC756_RS05650	COG0471	metal ion transport
IC756_RS05665	COG3051	citrate lyase alpha subunit
IC756_RS05670	COG2301	Belongs to the HpcH HpaI aldolase family
IC756_RS05680	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IC756_RS05685	COG3290	protein histidine kinase activity
IC756_RS05690	COG4565	transcriptional regulatory protein
IC756_RS05695	COG3069	C4-dicarboxylate transmembrane transporter activity
IC756_RS05715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC756_RS05720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC756_RS05730	COG0583	DNA-binding transcription factor activity
IC756_RS05745	COG1686	Belongs to the peptidase S11 family
IC756_RS05750	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IC756_RS05755	COG0772	Belongs to the SEDS family
IC756_RS05760	COG0768	penicillin binding
IC756_RS05770	COG0799	negative regulation of ribosome biogenesis
IC756_RS05775	COG0406	alpha-ribazole phosphatase activity
IC756_RS05785	COG1466	dna polymerase III delta subunit
IC756_RS05800	COG2888	peptidyl-tyrosine sulfation
IC756_RS05805	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IC756_RS05815	COG2214	Heat shock protein DnaJ domain protein
IC756_RS05820	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IC756_RS05830	COG2214	Heat shock protein DnaJ domain protein
IC756_RS05835	COG0443	Heat shock 70 kDa protein
IC756_RS05845	COG1126	abc transporter atp-binding protein
IC756_RS05850	COG0765	amino acid transport
IC756_RS05855	COG0765	amino acid transport
IC756_RS05860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC756_RS05865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IC756_RS05870	COG4535	Mg2 and Co2 transporter CorC
IC756_RS05880	COG1702	phosphate starvation-inducible protein PhoH
IC756_RS05890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC756_RS05935	COG0367	asparagine synthase
IC756_RS05940	COG0647	UMP catabolic process
IC756_RS05945	COG1940	carbohydrate kinase activity
IC756_RS05945	COG1846	Transcriptional regulator
IC756_RS05950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IC756_RS05960	COG2190	(PTS) system
IC756_RS05960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS05960	COG1263	PTS System
IC756_RS05980	COG0735	belongs to the Fur family
IC756_RS05990	COG0716	FMN binding
IC756_RS06000	COG0596	Alpha beta hydrolase
IC756_RS06005	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IC756_RS06010	COG0033	Phosphoglucomutase
IC756_RS06020	COG0745	RESPONSE REGULATOR receiver
IC756_RS06025	COG2205	protein histidine kinase activity
IC756_RS06070	COG3272	Protein of unknown function (DUF1722)
IC756_RS06075	COG0415	Belongs to the DNA photolyase family
IC756_RS06085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC756_RS06090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IC756_RS06095	COG1984	allophanate hydrolase subunit 2
IC756_RS06110	COG3180	Ammonia monooxygenase
IC756_RS06115	COG3539	Fimbrial protein
IC756_RS06120	COG3121	Chaperone
IC756_RS06125	COG3188	usher protein
IC756_RS06130	COG3539	Fimbrial protein
IC756_RS06135	COG0372	Belongs to the citrate synthase family
IC756_RS06145	COG2009	succinate dehydrogenase
IC756_RS06150	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC756_RS06155	COG1053	succinate dehydrogenase
IC756_RS06160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC756_RS06165	COG0567	Dehydrogenase, E1 component
IC756_RS06170	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC756_RS06180	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IC756_RS06190	COG0583	DNA-binding transcription factor activity
IC756_RS06195	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IC756_RS06200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC756_RS06200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC756_RS06205	COG1301	dicarboxylic acid transport
IC756_RS06220	COG3799	methylaspartate ammonia-lyase activity
IC756_RS06225	COG4865	methylaspartate mutase activity
IC756_RS06235	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IC756_RS06250	COG1271	oxidase subunit
IC756_RS06255	COG1294	oxidase, subunit
IC756_RS06260	COG4890	Cyd operon protein YbgT
IC756_RS06265	COG3790	cyd operon protein YbgE
IC756_RS06270	COG0824	Thioesterase
IC756_RS06275	COG0811	peptide transport
IC756_RS06280	COG0848	biopolymer transport protein
IC756_RS06285	COG3064	Membrane
IC756_RS06295	COG2885	chlorophyll binding
IC756_RS06300	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IC756_RS06350	COG3201	nicotinamide mononucleotide transporter
IC756_RS06355	COG1230	cation diffusion facilitator family transporter
IC756_RS06365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC756_RS06375	COG2017	converts alpha-aldose to the beta-anomer
IC756_RS06385	COG1085	galactose-1-phosphate uridylyltransferase
IC756_RS06390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC756_RS06395	COG1119	ATPase activity
IC756_RS06400	COG2005	Transcriptional regulator
IC756_RS06400	COG3585	molybdate ion transport
IC756_RS06410	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC756_RS06415	COG4149	molybdate abc transporter
IC756_RS06420	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC756_RS06425	COG0561	phosphatase activity
IC756_RS06435	COG0583	DNA-binding transcription factor activity
IC756_RS06440	COG2828	Protein conserved in bacteria
IC756_RS06445	COG0471	metal ion transport
IC756_RS06450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC756_RS06455	COG4677	pectinesterase activity
IC756_RS06460	COG0582	viral genome integration into host DNA
IC756_RS06510	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IC756_RS06515	COG5532	Uncharacterized conserved protein (DUF2303)
IC756_RS06560	COG1846	Transcriptional regulator
IC756_RS06575	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IC756_RS06585	COG1403	HNH endonuclease
IC756_RS06635	COG1802	Transcriptional regulator
IC756_RS06635	COG4626	Terminase
IC756_RS06645	COG4695	Portal protein
IC756_RS06690	COG4386	tail sheath protein
IC756_RS06715	COG4228	DNA circulation
IC756_RS06735	COG3299	homolog of phage Mu protein gp47
IC756_RS06740	COG3778	Protein conserved in bacteria
IC756_RS06770	COG2246	polysaccharide biosynthetic process
IC756_RS06775	COG1881	PFAM PEBP family protein
IC756_RS06780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IC756_RS06795	COG2226	methyltransferase
IC756_RS06800	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IC756_RS06810	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IC756_RS06820	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC756_RS06830	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IC756_RS06835	COG0314	molybdopterin synthase activity
IC756_RS06840	COG0670	Belongs to the BI1 family
IC756_RS06845	COG0670	Belongs to the BI1 family
IC756_RS06850	COG0392	lysyltransferase activity
IC756_RS06855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC756_RS06860	COG3568	Endonuclease Exonuclease Phosphatase
IC756_RS06870	COG0842	Transport permease protein
IC756_RS06875	COG0842	Transport permease protein
IC756_RS06880	COG1131	(ABC) transporter
IC756_RS06890	COG1309	transcriptional regulator
IC756_RS06895	COG0513	Belongs to the DEAD box helicase family
IC756_RS06900	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
IC756_RS06905	COG1199	ATP-dependent helicase activity
IC756_RS06910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IC756_RS06915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IC756_RS06925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC756_RS06950	COG0668	transmembrane transport
IC756_RS06955	COG1126	abc transporter atp-binding protein
IC756_RS06960	COG0765	amino acid transport
IC756_RS06965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC756_RS06975	COG5006	permease, DMT superfamily
IC756_RS06985	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC756_RS06990	COG2194	sulfuric ester hydrolase activity
IC756_RS07000	COG1321	iron dependent repressor
IC756_RS07005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IC756_RS07010	COG1376	ErfK ybiS ycfS ynhG family protein
IC756_RS07015	COG0488	(ABC) transporter
IC756_RS07025	COG2271	Major facilitator Superfamily
IC756_RS07040	COG0561	phosphatase activity
IC756_RS07045	COG1882	Formate acetyltransferase
IC756_RS07050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IC756_RS07055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC756_RS07060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IC756_RS07065	COG0303	'Molybdopterin
IC756_RS07070	COG1446	asparaginase
IC756_RS07080	COG0747	negative chemotaxis
IC756_RS07095	COG2200	EAL domain
IC756_RS07100	COG2199	diguanylate cyclase activity
IC756_RS07125	COG2133	pyrroloquinoline quinone binding
IC756_RS07130	COG0625	glutathione transferase activity
IC756_RS07135	COG1686	Belongs to the peptidase S11 family
IC756_RS07140	COG1349	DNA-binding transcription factor activity
IC756_RS07145	COG0671	phosphoesterase, PA-phosphatase related
IC756_RS07150	COG2814	Major facilitator Superfamily
IC756_RS07160	COG0561	phosphatase activity
IC756_RS07165	COG0738	Major facilitator superfamily
IC756_RS07170	COG3226	Transcriptional regulator
IC756_RS07175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC756_RS07215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC756_RS07260	COG4695	Portal protein
IC756_RS07360	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IC756_RS07370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IC756_RS07425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC756_RS07435	COG0778	Nitroreductase
IC756_RS07450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IC756_RS07455	COG3842	ATPase activity
IC756_RS07460	COG1176	ABC-type spermidine putrescine transport system, permease component I
IC756_RS07465	COG1177	transmembrane transport
IC756_RS07495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC756_RS07500	COG4160	amino acid transport
IC756_RS07505	COG4215	(ABC) transporter
IC756_RS07510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC756_RS07515	COG1126	abc transporter atp-binding protein
IC756_RS07535	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC756_RS07540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC756_RS07545	COG0702	epimerase
IC756_RS07550	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IC756_RS07555	COG0028	Belongs to the TPP enzyme family
IC756_RS07560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC756_RS07570	COG2431	L-lysine efflux transmembrane transporter activity
IC756_RS07575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IC756_RS07580	COG3593	DNA synthesis involved in DNA repair
IC756_RS07585	COG2990	Protein conserved in bacteria
IC756_RS07590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC756_RS07600	COG1278	Cold shock
IC756_RS07610	COG0542	response to heat
IC756_RS07635	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IC756_RS07640	COG4988	ABC transporter
IC756_RS07645	COG0492	ferredoxin-NADP+ reductase activity
IC756_RS07650	COG1522	sequence-specific DNA binding
IC756_RS07655	COG1178	ABC-type Fe3 transport system permease component
IC756_RS07655	COG1674	ftsk spoiiie
IC756_RS07665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC756_RS07730	COG5301	cellulose 1,4-beta-cellobiosidase activity
IC756_RS07730	COG5301	cellulose 1,4-beta-cellobiosidase activity
IC756_RS07810	COG4695	Portal protein
IC756_RS07835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IC756_RS07925	COG4974	Belongs to the 'phage' integrase family
IC756_RS07930	COG0243	molybdopterin cofactor binding
IC756_RS07935	COG0437	4 iron, 4 sulfur cluster binding
IC756_RS07940	COG3302	dmso reductase anchor subunit
IC756_RS07945	COG1335	isochorismatase
IC756_RS07955	COG0531	amino acid
IC756_RS07965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IC756_RS07970	COG1882	Formate acetyltransferase
IC756_RS07975	COG2116	formate transmembrane transporter activity
IC756_RS07980	COG1944	ATP diphosphatase activity
IC756_RS07985	COG2323	membrane
IC756_RS08000	COG0501	Belongs to the peptidase M48B family
IC756_RS08010	COG0539	negative regulation of cytoplasmic translation
IC756_RS08020	COG0658	competence protein
IC756_RS08020	COG2333	competence protein COMEC
IC756_RS08035	COG3214	Protein conserved in bacteria
IC756_RS08050	COG3173	Aminoglycoside phosphotransferase
IC756_RS08055	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IC756_RS08060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC756_RS08070	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IC756_RS08080	COG2989	Protein conserved in bacteria
IC756_RS08085	COG3108	Peptidase M15
IC756_RS08090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC756_RS08095	COG1448	Aminotransferase
IC756_RS08115	COG0308	aminopeptidase N
IC756_RS08130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC756_RS08140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC756_RS08145	COG0431	NADPH-dependent FMN reductase
IC756_RS08160	COG0633	Ferredoxin
IC756_RS08160	COG3217	Mosc domain protein beta barrel domain protein
IC756_RS08170	COG0488	(ABC) transporter
IC756_RS08175	COG2995	paraquat-inducible protein a
IC756_RS08180	COG3008	intermembrane lipid transfer
IC756_RS08180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC756_RS08185	COG3009	Protein conserved in bacteria
IC756_RS08190	COG3130	regulation of translation
IC756_RS08200	COG1067	ATP-dependent peptidase activity
IC756_RS08210	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC756_RS08210	COG2885	chlorophyll binding
IC756_RS08220	COG3070	regulator of competence-specific genes
IC756_RS08225	COG1289	transmembrane transporter activity
IC756_RS08230	COG3304	Inner membrane component domain
IC756_RS08235	COG0210	DNA helicase
IC756_RS08250	COG1832	CoA-binding protein
IC756_RS08265	COG1254	Belongs to the acylphosphatase family
IC756_RS08270	COG2920	part of a sulfur-relay system
IC756_RS08275	COG0670	Belongs to the BI1 family
IC756_RS08285	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IC756_RS08290	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IC756_RS08295	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
IC756_RS08300	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IC756_RS08305	COG1999	signal sequence binding
IC756_RS08310	COG1773	rubredoxin
IC756_RS08315	COG1271	oxidase subunit
IC756_RS08320	COG1294	oxidase, subunit
IC756_RS08335	COG1278	Cold shock
IC756_RS08340	COG1278	Cold shock
IC756_RS08360	COG0348	domain, Protein
IC756_RS08365	COG0784	Response regulator, receiver
IC756_RS08365	COG2198	Histidine kinase
IC756_RS08365	COG2205	protein histidine kinase activity
IC756_RS08370	COG1879	ABC-type sugar transport system periplasmic component
IC756_RS08375	COG0745	RESPONSE REGULATOR receiver
IC756_RS08380	COG3005	denitrification pathway
IC756_RS08385	COG0243	molybdopterin cofactor binding
IC756_RS08425	COG3729	General stress protein
IC756_RS08430	COG2233	PERMEase
IC756_RS08465	COG1309	transcriptional regulator
IC756_RS08470	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC756_RS08470	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC756_RS08470	COG0506	proline dehydrogenase activity
IC756_RS08480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC756_RS08495	COG2822	iron ion transport
IC756_RS08505	COG1702	phosphate starvation-inducible protein PhoH
IC756_RS08530	COG3381	protein complex oligomerization
IC756_RS08540	COG1462	curli production assembly transport component CsgG
IC756_RS08555	COG2197	response regulator
IC756_RS08580	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IC756_RS08585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC756_RS08600	COG2943	transferase activity, transferring hexosyl groups
IC756_RS08605	COG5645	(Lipo)protein
IC756_RS08620	COG1560	Kdo2-lipid A biosynthetic process
IC756_RS08635	COG3038	cytochrome b561
IC756_RS08670	COG2999	glutathione oxidoreductase activity
IC756_RS08680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC756_RS08690	COG0673	inositol 2-dehydrogenase activity
IC756_RS08695	COG0728	peptidoglycan biosynthetic process
IC756_RS08700	COG3418	PFAM FlgN family protein
IC756_RS08705	COG2747	anti-sigma28 factor FlgM
IC756_RS08710	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IC756_RS08715	COG1815	bacterial-type flagellum-dependent cell motility
IC756_RS08720	COG1558	bacterial-type flagellum-dependent cell motility
IC756_RS08725	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IC756_RS08730	COG1749	Flagellar hook protein flgE
IC756_RS08735	COG4787	bacterial-type flagellum-dependent cell motility
IC756_RS08740	COG4786	Flagellar basal body rod
IC756_RS08755	COG3951	Flagellar rod assembly protein muramidase FlgJ
IC756_RS08755	COG1705	Flagellar rod assembly protein muramidase FlgJ
IC756_RS08760	COG1256	bacterial-type flagellum assembly
IC756_RS08765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IC756_RS08780	COG1530	ribonuclease E activity
IC756_RS08785	COG0564	pseudouridine synthase activity
IC756_RS08790	COG0424	maF-like protein
IC756_RS08795	COG1399	metal-binding, possibly nucleic acid-binding protein
IC756_RS08815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC756_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS08830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IC756_RS08835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC756_RS08840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC756_RS08850	COG0470	DNA polymerase III
IC756_RS08855	COG0084	hydrolase, TatD family'
IC756_RS08860	COG1263	PTS System
IC756_RS08860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS08865	COG4773	Receptor
IC756_RS08870	COG0537	adenosine 5'-monophosphoramidase activity
IC756_RS08875	COG5633	Lipoprotein
IC756_RS08880	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
IC756_RS08900	COG1252	NADH dehydrogenase
IC756_RS08905	COG3134	Outer membrane lipoprotein
IC756_RS08910	COG1309	transcriptional regulator
IC756_RS08920	COG1376	ErfK ybiS ycfS ynhG family protein
IC756_RS08920	COG1388	LysM domain
IC756_RS08925	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC756_RS08930	COG4763	Acyl-transferase
IC756_RS08935	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC756_RS08945	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC756_RS08955	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC756_RS08960	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC756_RS08970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IC756_RS08975	COG1177	transmembrane transport
IC756_RS08985	COG3842	ATPase activity
IC756_RS08995	COG2850	peptidyl-arginine hydroxylation
IC756_RS09000	COG2205	protein histidine kinase activity
IC756_RS09010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC756_RS09030	COG1187	pseudouridine synthase activity
IC756_RS09035	COG0538	isocitrate dehydrogenase activity
IC756_RS09055	COG5562	phage envelope protein
IC756_RS09060	COG0789	Transcriptional regulator
IC756_RS09065	COG2200	EAL domain
IC756_RS09090	COG2200	EAL domain
IC756_RS09145	COG2894	cell division
IC756_RS09175	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC756_RS09190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC756_RS09195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC756_RS09200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IC756_RS09215	COG2719	SpoVR family
IC756_RS09225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC756_RS09245	COG1619	proteins homologs of microcin C7 resistance protein MccF
IC756_RS09255	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IC756_RS09270	COG0157	Belongs to the NadC ModD family
IC756_RS09275	COG0500	methyltransferase
IC756_RS09280	COG1120	ATPase activity
IC756_RS09285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC756_RS09300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS09300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC756_RS09300	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IC756_RS09305	COG1461	Dihydroxyacetone kinase
IC756_RS09310	COG2376	Dihydroxyacetone kinase
IC756_RS09315	COG3284	Transcriptional regulator
IC756_RS09320	COG3468	outer membrane autotransporter barrel domain protein
IC756_RS09325	COG0012	GTP binding
IC756_RS09340	COG0659	secondary active sulfate transmembrane transporter activity
IC756_RS09345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC756_RS09370	COG2890	protein-(glutamine-N5) methyltransferase activity
IC756_RS09375	COG3094	Invasion gene expression up-regulator, SirB
IC756_RS09380	COG2912	Transglutaminase-like superfamily
IC756_RS09400	COG0387	Pfam Sodium calcium exchanger
IC756_RS09405	COG4572	Cation transport regulator
IC756_RS09410	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IC756_RS09415	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC756_RS09420	COG4932	domain protein
IC756_RS09425	COG2197	response regulator
IC756_RS09430	COG3850	Histidine kinase
IC756_RS09435	COG2223	nitrite transmembrane transporter activity
IC756_RS09440	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IC756_RS09445	COG1140	nitrate reductase beta subunit
IC756_RS09450	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IC756_RS09455	COG2181	nitrate reductase activity
IC756_RS09480	COG0788	formyltetrahydrofolate deformylase activity
IC756_RS09490	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC756_RS09495	COG0745	RESPONSE REGULATOR receiver
IC756_RS09500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC756_RS09510	COG1435	thymidine kinase activity
IC756_RS09515	COG1012	belongs to the aldehyde dehydrogenase family
IC756_RS09515	COG1454	alcohol dehydrogenase
IC756_RS09520	COG2095	MarC family integral membrane protein
IC756_RS09530	COG4166	transmembrane transport
IC756_RS09535	COG0601	transmembrane transport
IC756_RS09540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC756_RS09545	COG0444	Belongs to the ABC transporter superfamily
IC756_RS09550	COG4608	Belongs to the ABC transporter superfamily
IC756_RS09570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC756_RS09575	COG2350	Protein conserved in bacteria
IC756_RS09580	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC756_RS09585	COG1607	acyl-coa hydrolase
IC756_RS09605	COG3047	cAMP biosynthetic process
IC756_RS09610	COG3685	Protein conserved in bacteria
IC756_RS09615	COG3685	Protein conserved in bacteria
IC756_RS09620	COG3729	General stress protein
IC756_RS09635	COG0134	indole-3-glycerol-phosphate synthase activity
IC756_RS09635	COG0135	phosphoribosylanthranilate isomerase activity
IC756_RS09640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IC756_RS09640	COG0512	Glutamine amidotransferase of anthranilate synthase
IC756_RS09645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC756_RS09655	COG0613	PHP domain protein
IC756_RS09660	COG0009	L-threonylcarbamoyladenylate synthase
IC756_RS09665	COG4907	membrane protein (DUF2207)
IC756_RS09670	COG1187	pseudouridine synthase activity
IC756_RS09675	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IC756_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS09685	COG0616	signal peptide processing
IC756_RS09695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC756_RS09700	COG0583	DNA-binding transcription factor activity
IC756_RS09720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC756_RS09730	COG0671	phosphoesterase, PA-phosphatase related
IC756_RS09735	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IC756_RS09740	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IC756_RS09750	COG0023	Translation Initiation Factor
IC756_RS09760	COG1349	DNA-binding transcription factor activity
IC756_RS09770	COG5001	Diguanylate cyclase
IC756_RS09785	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC756_RS09785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC756_RS09790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IC756_RS09795	COG2852	Protein conserved in bacteria
IC756_RS09800	COG4172	Belongs to the ABC transporter superfamily
IC756_RS09805	COG4172	Belongs to the ABC transporter superfamily
IC756_RS09810	COG4171	peptide transport system, permease
IC756_RS09815	COG4168	peptide transport system, permease
IC756_RS09820	COG4166	transmembrane transport
IC756_RS09830	COG0531	amino acid
IC756_RS09840	COG0174	glutamine synthetase
IC756_RS09845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC756_RS09850	COG1396	sequence-specific DNA binding
IC756_RS09850	COG1917	Cupin 2, conserved barrel domain protein
IC756_RS09855	COG1012	belongs to the aldehyde dehydrogenase family
IC756_RS09860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IC756_RS09865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC756_RS09870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IC756_RS09875	COG1842	Phage shock protein A
IC756_RS09885	COG1983	PspC domain protein
IC756_RS09895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IC756_RS09900	COG3106	COG3106 Predicted ATPase
IC756_RS09910	COG3283	Transcriptional regulator of aromatic amino acids metabolism
IC756_RS09915	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IC756_RS09920	COG4948	Mandelate Racemase Muconate Lactonizing
IC756_RS09925	COG2866	Carboxypeptidase
IC756_RS09930	COG0702	epimerase
IC756_RS09940	COG1073	alpha beta
IC756_RS09945	COG0583	DNA-binding transcription factor activity
IC756_RS09950	COG4166	transmembrane transport
IC756_RS09955	COG0668	transmembrane transport
IC756_RS09960	COG3182	Iron-regulated membrane protein
IC756_RS09965	COG0589	response to stress
IC756_RS09970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC756_RS09975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC756_RS09980	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IC756_RS09985	COG1473	amidohydrolase
IC756_RS09990	COG1473	amidohydrolase
IC756_RS09995	COG0583	DNA-binding transcription factor activity
IC756_RS10000	COG2840	Smr protein MutS2
IC756_RS10005	COG3706	GGDEF domain
IC756_RS10015	COG0513	Belongs to the DEAD box helicase family
IC756_RS10025	COG0589	response to stress
IC756_RS10030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IC756_RS10035	COG1013	pyruvate-flavodoxin oxidoreductase activity
IC756_RS10035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC756_RS10035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IC756_RS10035	COG0674	pyruvate-flavodoxin oxidoreductase activity
IC756_RS10040	COG3042	response to heat
IC756_RS10045	COG3187	Heat shock protein
IC756_RS10050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IC756_RS10055	COG2911	Protein conserved in bacteria
IC756_RS10065	COG3784	Protein of unknown function (DUF1318)
IC756_RS10075	COG0667	Aldo Keto reductase
IC756_RS10085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC756_RS10090	COG4589	Belongs to the CDS family
IC756_RS10095	COG2267	carboxylic ester hydrolase activity
IC756_RS10100	COG0671	phosphoesterase, PA-phosphatase related
IC756_RS10100	COG2453	phosphatase
IC756_RS10110	COG1643	Atp-dependent helicase
IC756_RS10125	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IC756_RS10130	COG1012	belongs to the aldehyde dehydrogenase family
IC756_RS10135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC756_RS10140	COG3038	cytochrome b561
IC756_RS10155	COG0840	transmembrane signaling receptor activity
IC756_RS10160	COG0583	DNA-binding transcription factor activity
IC756_RS10165	COG5383	Protein conserved in bacteria
IC756_RS10175	COG2841	Protein conserved in bacteria
IC756_RS10180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC756_RS10190	COG2826	transposase and inactivated derivatives, IS30 family
IC756_RS10200	COG1275	C4-dicarboxylate transporter malic acid transport protein
IC756_RS10205	COG0500	methyltransferase
IC756_RS10215	COG3135	benzoate transporter
IC756_RS10220	COG1396	sequence-specific DNA binding
IC756_RS10225	COG0826	peptidase U32
IC756_RS10235	COG1724	mRNA binding
IC756_RS10240	COG1598	PFAM Uncharacterised protein family UPF0150
IC756_RS10245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC756_RS10250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IC756_RS10255	COG3842	ATPase activity
IC756_RS10260	COG1176	ABC-type spermidine putrescine transport system, permease component I
IC756_RS10265	COG1177	transmembrane transport
IC756_RS10295	COG3238	Protein conserved in bacteria
IC756_RS10300	COG1247	-acetyltransferase
IC756_RS10305	COG2130	NADP-dependent
IC756_RS10310	COG1802	Transcriptional regulator
IC756_RS10315	COG4772	TonB-dependent receptor
IC756_RS10320	COG3391	amine dehydrogenase activity
IC756_RS10325	COG1113	amino acid transport
IC756_RS10335	COG0625	glutathione transferase activity
IC756_RS10345	COG3501	Rhs element vgr protein
IC756_RS10375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC756_RS10380	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IC756_RS10390	COG0384	phenazine biosynthesis protein PhzF
IC756_RS10395	COG2181	nitrate reductase activity
IC756_RS10400	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IC756_RS10405	COG1140	nitrate reductase beta subunit
IC756_RS10410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IC756_RS10415	COG2223	nitrite transmembrane transporter activity
IC756_RS10420	COG4886	Leucine-rich repeat (LRR) protein
IC756_RS10425	COG4886	Leucine-rich repeat (LRR) protein
IC756_RS10435	COG0697	spore germination
IC756_RS10445	COG0437	4 iron, 4 sulfur cluster binding
IC756_RS10450	COG2864	formate dehydrogenase
IC756_RS10455	COG3093	addiction module antidote protein HigA
IC756_RS10465	COG1064	alcohol dehydrogenase
IC756_RS10485	COG1764	response to oxidative stress
IC756_RS10490	COG4608	Belongs to the ABC transporter superfamily
IC756_RS10495	COG0444	Belongs to the ABC transporter superfamily
IC756_RS10500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC756_RS10505	COG0601	transmembrane transport
IC756_RS10510	COG0747	negative chemotaxis
IC756_RS10515	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IC756_RS10520	COG2200	EAL domain
IC756_RS10520	COG2202	Pas domain
IC756_RS10520	COG2199	diguanylate cyclase activity
IC756_RS10535	COG1649	PFAM Uncharacterised BCR, COG1649
IC756_RS10540	COG0531	amino acid
IC756_RS10545	COG0076	glutamate decarboxylase activity
IC756_RS10550	COG0612	Peptidase, M16
IC756_RS10555	COG4771	TonB-dependent receptor
IC756_RS10560	COG4178	(ABC) transporter
IC756_RS10570	COG0641	radical SAM
IC756_RS10580	COG2207	Transcriptional regulator
IC756_RS10590	COG0243	molybdopterin cofactor binding
IC756_RS10595	COG3539	Fimbrial protein
IC756_RS10600	COG3539	Fimbrial protein
IC756_RS10605	COG3539	Fimbrial protein
IC756_RS10610	COG3188	usher protein
IC756_RS10620	COG3539	Fimbrial protein
IC756_RS10640	COG0667	Aldo Keto reductase
IC756_RS10645	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC756_RS10665	COG0656	L-ascorbic acid biosynthetic process
IC756_RS10685	COG3550	peptidyl-serine autophosphorylation
IC756_RS10690	COG1396	sequence-specific DNA binding
IC756_RS10750	COG3781	membrane
IC756_RS10760	COG2199	diguanylate cyclase activity
IC756_RS10770	COG2066	Belongs to the glutaminase family
IC756_RS10775	COG1012	belongs to the aldehyde dehydrogenase family
IC756_RS10780	COG0583	DNA-binding transcription factor activity
IC756_RS10800	COG1846	Transcriptional regulator
IC756_RS10805	COG4977	sequence-specific DNA binding
IC756_RS10815	COG0697	spore germination
IC756_RS10820	COG2814	Major facilitator Superfamily
IC756_RS10830	COG3706	GGDEF domain
IC756_RS10835	COG3111	PFAM Bacterial OB fold (BOF) protein
IC756_RS10840	COG0339	signal peptide processing
IC756_RS10845	COG4221	oxidoreductase activity
IC756_RS10850	COG1802	Transcriptional regulator
IC756_RS10860	COG0246	Mannitol dehydrogenase
IC756_RS10865	COG0477	Major facilitator Superfamily
IC756_RS10870	COG1063	alcohol dehydrogenase
IC756_RS10875	COG4948	Mandelate Racemase Muconate Lactonizing
IC756_RS10890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC756_RS10905	COG0243	molybdopterin cofactor binding
IC756_RS10910	COG0243	molybdopterin cofactor binding
IC756_RS10915	COG0437	4 iron, 4 sulfur cluster binding
IC756_RS10920	COG3302	dmso reductase anchor subunit
IC756_RS10925	COG3381	protein complex oligomerization
IC756_RS10935	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IC756_RS10940	COG1940	carbohydrate kinase activity
IC756_RS10945	COG0583	DNA-binding transcription factor activity
IC756_RS10950	COG2814	Major facilitator Superfamily
IC756_RS10965	COG3591	Belongs to the peptidase S1B family
IC756_RS10980	COG0628	permease
IC756_RS10985	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IC756_RS10990	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IC756_RS11000	COG0531	amino acid
IC756_RS11010	COG3136	membrane protein required for alginate biosynthesis
IC756_RS11015	COG0745	RESPONSE REGULATOR receiver
IC756_RS11020	COG2205	protein histidine kinase activity
IC756_RS11030	COG0114	fumarate hydratase activity
IC756_RS11035	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC756_RS11035	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC756_RS11040	COG1482	cell wall glycoprotein biosynthetic process
IC756_RS11045	COG5339	Protein conserved in bacteria
IC756_RS11060	COG3250	beta-galactosidase activity
IC756_RS11065	COG1309	transcriptional regulator
IC756_RS11070	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS11075	COG1609	Transcriptional regulator
IC756_RS11080	COG1263	PTS System
IC756_RS11080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS11085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IC756_RS11095	COG0673	inositol 2-dehydrogenase activity
IC756_RS11135	COG4659	FMN binding
IC756_RS11145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC756_RS11150	COG3104	oligopeptide transport
IC756_RS11155	COG0625	glutathione transferase activity
IC756_RS11160	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IC756_RS11175	COG3895	Periplasmic Protein
IC756_RS11185	COG3133	Outer membrane lipoprotein
IC756_RS11200	COG1566	PFAM secretion protein HlyD family protein
IC756_RS11205	COG1289	transmembrane transporter activity
IC756_RS11210	COG2032	superoxide dismutase activity
IC756_RS11215	COG4989	oxidoreductase activity
IC756_RS11220	COG3313	Fe-S protein
IC756_RS11225	COG1309	transcriptional regulator
IC756_RS11230	COG1902	pentaerythritol trinitrate reductase activity
IC756_RS11235	COG0346	lactoylglutathione lyase activity
IC756_RS11245	COG1201	RNA secondary structure unwinding
IC756_RS11250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC756_RS11255	COG0791	NLP P60 protein
IC756_RS11260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC756_RS11265	COG2814	Major facilitator Superfamily
IC756_RS11280	COG0583	DNA-binding transcription factor activity
IC756_RS11285	COG2814	Major facilitator Superfamily
IC756_RS11290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC756_RS11295	COG0307	riboflavin synthase, alpha
IC756_RS11305	COG3468	outer membrane autotransporter barrel domain protein
IC756_RS11325	COG4529	Protein conserved in bacteria
IC756_RS11335	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IC756_RS11340	COG0437	4 iron, 4 sulfur cluster binding
IC756_RS11350	COG2414	aldehyde ferredoxin oxidoreductase
IC756_RS11355	COG0437	4 iron, 4 sulfur cluster binding
IC756_RS11365	COG0469	pyruvate kinase activity
IC756_RS11370	COG4238	major outer membrane lipoprotein
IC756_RS11375	COG1376	ErfK ybiS ycfS ynhG family protein
IC756_RS11390	COG0719	Fe-S assembly protein
IC756_RS11395	COG0396	ATPase activity
IC756_RS11400	COG0719	Fe-S assembly protein
IC756_RS11405	COG0316	Belongs to the HesB IscA family
IC756_RS11415	COG2050	protein possibly involved in aromatic compounds catabolism
IC756_RS11420	COG0277	FAD linked oxidase domain protein
IC756_RS11420	COG0247	lactate metabolic process
IC756_RS11425	COG0628	permease
IC756_RS11440	COG0738	Major facilitator superfamily
IC756_RS11445	COG2271	Major facilitator Superfamily
IC756_RS11460	COG4670	ketone body catabolic process
IC756_RS11465	COG1960	acyl-CoA dehydrogenase activity
IC756_RS11470	COG1917	Cupin 2, conserved barrel domain protein
IC756_RS11470	COG2207	Transcriptional regulator
IC756_RS11475	COG2086	electron transfer activity
IC756_RS11480	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IC756_RS11485	COG0644	oxidoreductase
IC756_RS11490	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC756_RS11495	COG0318	PFAM AMP-dependent synthetase and ligase
IC756_RS11500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC756_RS11500	COG0574	Belongs to the PEP-utilizing enzyme family
IC756_RS11510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC756_RS11515	COG4256	Hemin uptake protein
IC756_RS11525	COG2200	EAL domain
IC756_RS11530	COG0791	NLP P60 protein
IC756_RS11540	COG0386	Belongs to the glutathione peroxidase family
IC756_RS11600	COG3137	Salt-induced outer membrane protein
IC756_RS11605	COG1105	Belongs to the carbohydrate kinase PfkB family
IC756_RS11615	COG3001	Fructosamine kinase
IC756_RS11625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC756_RS11630	COG1988	membrane-bound metal-dependent
IC756_RS11635	COG1823	symporter activity
IC756_RS11650	COG0753	catalase activity
IC756_RS11660	COG1486	melibiose metabolic process
IC756_RS11665	COG1917	Cupin 2, conserved barrel domain protein
IC756_RS11665	COG2169	Transcriptional regulator
IC756_RS11670	COG1447	Phosphotransferase system cellobiose-specific component IIA
IC756_RS11675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC756_RS11680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC756_RS11685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC756_RS11695	COG0322	excinuclease ABC activity
IC756_RS11705	COG3678	ATP-independent chaperone mediated protein folding
IC756_RS11735	COG0708	Exodeoxyribonuclease III
IC756_RS11740	COG0398	Pfam SNARE associated Golgi protein
IC756_RS11750	COG0398	Pfam SNARE associated Golgi protein
IC756_RS11755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC756_RS11760	COG4134	Bacterial extracellular solute-binding protein
IC756_RS11765	COG4135	transport system, permease component
IC756_RS11770	COG4136	ATPase activity
IC756_RS11775	COG2897	thiosulfate sulfurtransferase activity
IC756_RS11780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC756_RS11785	COG0494	nUDIX hydrolase
IC756_RS11795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC756_RS11800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC756_RS11810	COG0778	Nitroreductase
IC756_RS11815	COG0616	signal peptide processing
IC756_RS11820	COG0252	asparaginase activity
IC756_RS11825	COG1335	isochorismatase
IC756_RS11830	COG2814	Major facilitator Superfamily
IC756_RS11835	COG1349	DNA-binding transcription factor activity
IC756_RS11840	COG0667	Aldo Keto reductase
IC756_RS11845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC756_RS11850	COG0191	fructose-bisphosphate aldolase activity
IC756_RS11855	COG1063	alcohol dehydrogenase
IC756_RS11860	COG2271	Major facilitator Superfamily
IC756_RS11865	COG1063	alcohol dehydrogenase
IC756_RS11870	COG3139	Protein of unknown function (DUF1315)
IC756_RS11880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC756_RS11885	COG0676	glucose-6-phosphate 1-epimerase activity
IC756_RS11890	COG0656	L-ascorbic acid biosynthetic process
IC756_RS11895	COG3713	MltA-interacting MipA family protein
IC756_RS11900	COG2766	serine protein kinase
IC756_RS11910	COG2199	diguanylate cyclase activity
IC756_RS11915	COG2199	diguanylate cyclase activity
IC756_RS11920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC756_RS11935	COG2207	Transcriptional regulator
IC756_RS11940	COG2807	transmembrane transport
IC756_RS11945	COG3189	MarR family transcriptional regulator
IC756_RS11950	COG3042	response to heat
IC756_RS11955	COG2199	diguanylate cyclase activity
IC756_RS11955	COG2203	Gaf domain
IC756_RS11970	COG2261	transglycosylase associated protein
IC756_RS11980	COG3615	Tellurite resistance protein tehB
IC756_RS11990	COG0583	DNA-binding transcription factor activity
IC756_RS11995	COG0473	3-isopropylmalate dehydrogenase activity
IC756_RS12000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC756_RS12005	COG4638	Rieske (2fe-2S)
IC756_RS12010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC756_RS12015	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IC756_RS12020	COG0318	PFAM AMP-dependent synthetase and ligase
IC756_RS12025	COG3065	identical protein binding
IC756_RS12030	COG1214	PFAM Peptidase M22, glycoprotease
IC756_RS12035	COG1199	ATP-dependent helicase activity
IC756_RS12040	COG0251	oxidation-reduction process
IC756_RS12055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC756_RS12065	COG1760	l-serine dehydratase
IC756_RS12070	COG2200	EAL domain
IC756_RS12075	COG1253	flavin adenine dinucleotide binding
IC756_RS12080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS12080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS12090	COG3716	PTS system mannose fructose sorbose family IID component
IC756_RS12105	COG2226	methyltransferase
IC756_RS12135	COG2826	transposase and inactivated derivatives, IS30 family
IC756_RS12140	COG1414	Transcriptional regulator
IC756_RS12145	COG2814	Major facilitator Superfamily
IC756_RS12155	COG0793	Belongs to the peptidase S41A family
IC756_RS12165	COG1956	GAF domain-containing protein
IC756_RS12170	COG2995	paraquat-inducible protein a
IC756_RS12175	COG3008	intermembrane lipid transfer
IC756_RS12195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC756_RS12205	COG1276	copper resistance
IC756_RS12210	COG2372	response to copper ion
IC756_RS12220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC756_RS12225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC756_RS12230	COG1770	oligopeptidase
IC756_RS12245	COG2979	Protein of unknown function (DUF533)
IC756_RS12255	COG3141	response to X-ray
IC756_RS12265	COG0800	Aldolase
IC756_RS12270	COG0129	dihydroxy-acid dehydratase activity
IC756_RS12275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IC756_RS12280	COG1737	Transcriptional regulator
IC756_RS12285	COG0469	pyruvate kinase activity
IC756_RS12290	COG1560	Kdo2-lipid A biosynthetic process
IC756_RS12295	COG0739	heme binding
IC756_RS12300	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IC756_RS12310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC756_RS12340	COG0217	transcriptional regulatory protein
IC756_RS12345	COG0494	nUDIX hydrolase
IC756_RS12355	COG1335	isochorismatase
IC756_RS12360	COG1801	Protein of unknown function DUF72
IC756_RS12365	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IC756_RS12380	COG0243	molybdopterin cofactor binding
IC756_RS12385	COG3005	denitrification pathway
IC756_RS12395	COG3102	Protein conserved in bacteria
IC756_RS12410	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IC756_RS12415	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IC756_RS12420	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IC756_RS12425	COG0745	RESPONSE REGULATOR receiver
IC756_RS12435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IC756_RS12440	COG0840	transmembrane signaling receptor activity
IC756_RS12445	COG0840	transmembrane signaling receptor activity
IC756_RS12450	COG0835	chemotaxis
IC756_RS12455	COG0643	Histidine kinase
IC756_RS12455	COG2198	Histidine kinase
IC756_RS12460	COG1360	Flagellar Motor Protein
IC756_RS12465	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IC756_RS12480	COG0589	response to stress
IC756_RS12490	COG1877	trehalose-phosphatase activity
IC756_RS12495	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC756_RS12505	COG1879	ABC-type sugar transport system periplasmic component
IC756_RS12510	COG1528	Iron-storage protein
IC756_RS12530	COG1528	Iron-storage protein
IC756_RS12540	COG0814	amino acid
IC756_RS12545	COG3012	SEC-C Motif Domain Protein
IC756_RS12545	COG3318	Belongs to the UPF0149 family
IC756_RS12575	COG2197	response regulator
IC756_RS12590	COG2197	response regulator
IC756_RS12595	COG1126	abc transporter atp-binding protein
IC756_RS12600	COG0765	amino acid transport
IC756_RS12610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC756_RS12620	COG1191	sigma factor activity
IC756_RS12630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IC756_RS12635	COG1516	flagellar protein fliS
IC756_RS12645	COG0366	Alpha amylase catalytic
IC756_RS12655	COG2391	methyltransferase activity
IC756_RS12660	COG0425	Belongs to the sulfur carrier protein TusA family
IC756_RS12665	COG2135	peptidase activity
IC756_RS12685	COG1766	The M ring may be actively involved in energy transduction
IC756_RS12690	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IC756_RS12695	COG1317	bacterial-type flagellum organization
IC756_RS12700	COG1157	protein secretion by the type III secretion system
IC756_RS12705	COG2882	bacterial-type flagellum organization
IC756_RS12710	COG3144	bacterial-type flagellum assembly
IC756_RS12715	COG1580	Controls the rotational direction of flagella during chemotaxis
IC756_RS12720	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IC756_RS12725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IC756_RS12730	COG3190	flagellar
IC756_RS12735	COG1338	Plays a role in the flagellum-specific transport system
IC756_RS12740	COG1987	bacterial-type flagellum assembly
IC756_RS12745	COG1684	flagellar biosynthetic protein fliR
IC756_RS12750	COG2197	response regulator
IC756_RS12775	COG5475	Uncharacterized small protein (DUF2158)
IC756_RS12780	COG2354	Protein conserved in bacteria
IC756_RS12785	COG0697	spore germination
IC756_RS12790	COG3727	T/G mismatch-specific endonuclease activity
IC756_RS12795	COG0270	DNA (cytosine-5-)-methyltransferase activity
IC756_RS12800	COG1418	mRNA catabolic process
IC756_RS12810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IC756_RS12825	COG2205	protein histidine kinase activity
IC756_RS12830	COG0745	RESPONSE REGULATOR receiver
IC756_RS12835	COG2351	hydroxyisourate hydrolase activity
IC756_RS12850	COG3443	Belongs to the bacterial solute-binding protein 9 family
IC756_RS12870	COG5301	cellulose 1,4-beta-cellobiosidase activity
IC756_RS12900	COG1196	nuclear chromosome segregation
IC756_RS12950	COG1030	water channel activity
IC756_RS12970	COG4220	transposase activity
IC756_RS13055	COG2207	Transcriptional regulator
IC756_RS13080	COG1403	HNH endonuclease
IC756_RS13120	COG1846	Transcriptional regulator
IC756_RS13145	COG1396	sequence-specific DNA binding
IC756_RS13180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC756_RS13210	COG2373	Large extracellular alpha-helical protein
IC756_RS13210	COG4932	domain protein
IC756_RS13210	COG1388	LysM domain
IC756_RS13220	COG0477	Major facilitator Superfamily
IC756_RS13225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC756_RS13230	COG0217	transcriptional regulatory protein
IC756_RS13240	COG0534	Mate efflux family protein
IC756_RS13250	COG0583	DNA-binding transcription factor activity
IC756_RS13255	COG0583	DNA-binding transcription factor activity
IC756_RS13265	COG1376	ErfK ybiS ycfS ynhG family protein
IC756_RS13280	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
IC756_RS13340	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IC756_RS13355	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IC756_RS13375	COG4656	Part of a membrane complex involved in electron transport
IC756_RS13400	COG1289	transmembrane transporter activity
IC756_RS13410	COG1686	Belongs to the peptidase S11 family
IC756_RS13415	COG2925	Exonuclease
IC756_RS13420	COG0531	amino acid
IC756_RS13430	COG0583	DNA-binding transcription factor activity
IC756_RS13435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC756_RS13460	COG0131	Imidazoleglycerol-phosphate dehydratase
IC756_RS13460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IC756_RS13465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC756_RS13480	COG0140	phosphoribosyl-ATP diphosphatase activity
IC756_RS13480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC756_RS13490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IC756_RS13495	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IC756_RS13530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC756_RS13540	COG0438	transferase activity, transferring glycosyl groups
IC756_RS13545	COG2327	Polysaccharide pyruvyl transferase
IC756_RS13550	COG2244	polysaccharide biosynthetic process
IC756_RS13555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC756_RS13560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC756_RS13565	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IC756_RS13565	COG0662	Cupin 2, conserved barrel domain protein
IC756_RS13570	COG0297	glycogen (starch) synthase activity
IC756_RS13575	COG1051	belongs to the nudix hydrolase family
IC756_RS13580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC756_RS13585	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IC756_RS13590	COG0110	maltose O-acetyltransferase activity
IC756_RS13595	COG1216	Glycosyl transferase, family 2
IC756_RS13605	COG0438	transferase activity, transferring glycosyl groups
IC756_RS13610	COG1045	serine acetyltransferase
IC756_RS13615	COG0463	Glycosyl transferase, family 2
IC756_RS13620	COG3206	protein involved in exopolysaccharide biosynthesis
IC756_RS13620	COG0489	protein tyrosine kinase activity
IC756_RS13625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC756_RS13630	COG1596	polysaccharide export
IC756_RS13640	COG1253	flavin adenine dinucleotide binding
IC756_RS13655	COG2982	Protein involved in outer membrane biogenesis
IC756_RS13665	COG0572	uridine kinase
IC756_RS13670	COG5002	protein histidine kinase activity
IC756_RS13670	COG5001	Diguanylate cyclase
IC756_RS13670	COG3447	MASE1 domain protein
IC756_RS13675	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IC756_RS13680	COG0443	Heat shock 70 kDa protein
IC756_RS13685	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
IC756_RS13690	COG3779	Protein conserved in bacteria
IC756_RS13695	COG0631	protein serine/threonine phosphatase activity
IC756_RS13700	COG4245	von Willebrand factor, type A
IC756_RS13745	COG2205	protein histidine kinase activity
IC756_RS13750	COG0745	RESPONSE REGULATOR receiver
IC756_RS13760	COG0826	peptidase U32
IC756_RS13780	COG1063	alcohol dehydrogenase
IC756_RS13785	COG3775	system Galactitol-specific IIC component
IC756_RS13790	COG3414	Phosphotransferase system galactitol-specific IIB component
IC756_RS13795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS13810	COG1830	Aldolase
IC756_RS13815	COG2211	Major facilitator Superfamily
IC756_RS13820	COG1397	ADP-ribosylglycohydrolase
IC756_RS13825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC756_RS13830	COG2188	Transcriptional regulator
IC756_RS13835	COG3757	hydrolase, family 25
IC756_RS13840	COG0351	phosphomethylpyrimidine kinase
IC756_RS13860	COG5455	response to cobalt ion
IC756_RS13865	COG3539	Fimbrial protein
IC756_RS13870	COG3188	usher protein
IC756_RS13875	COG3121	Chaperone
IC756_RS13880	COG3539	Fimbrial protein
IC756_RS13890	COG0489	protein tyrosine kinase activity
IC756_RS13900	COG3831	ATPase activity
IC756_RS13905	COG3831	ATPase activity
IC756_RS13910	COG3831	ATPase activity
IC756_RS13920	COG0714	Associated with various cellular activities
IC756_RS13925	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IC756_RS13930	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IC756_RS13935	COG4715	Zinc finger, swim domain protein
IC756_RS13940	COG4808	Protein conserved in bacteria
IC756_RS13945	COG4807	Protein conserved in bacteria
IC756_RS13950	COG3279	Response regulator of the LytR AlgR family
IC756_RS13955	COG3275	phosphorelay sensor kinase activity
IC756_RS13960	COG0789	Transcriptional regulator
IC756_RS13970	COG1174	glycine betaine transport
IC756_RS13975	COG1125	glycine betaine transport
IC756_RS13980	COG1174	glycine betaine transport
IC756_RS13985	COG1732	Glycine betaine
IC756_RS13990	COG1472	Belongs to the glycosyl hydrolase 3 family
IC756_RS13995	COG0277	FAD linked oxidase domain protein
IC756_RS14000	COG1686	Belongs to the peptidase S11 family
IC756_RS14010	COG0586	Pfam SNARE associated Golgi protein
IC756_RS14015	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS14030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC756_RS14040	COG1346	cytolysis
IC756_RS14050	COG2949	membrane
IC756_RS14060	COG0493	'glutamate synthase
IC756_RS14065	COG0167	dihydroorotate dehydrogenase activity
IC756_RS14065	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC756_RS14070	COG4211	Belongs to the binding-protein-dependent transport system permease family
IC756_RS14075	COG1129	ABC transporter
IC756_RS14080	COG1879	ABC-type sugar transport system periplasmic component
IC756_RS14085	COG1609	Transcriptional regulator
IC756_RS14090	COG2311	Membrane
IC756_RS14100	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC756_RS14105	COG4771	TonB-dependent receptor
IC756_RS14110	COG0833	amino acid
IC756_RS14115	COG0583	DNA-binding transcription factor activity
IC756_RS14120	COG2855	membrane
IC756_RS14130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC756_RS14130	COG1522	sequence-specific DNA binding
IC756_RS14135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IC756_RS14145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC756_RS14150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IC756_RS14155	COG2313	pseudouridylate synthase activity
IC756_RS14160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC756_RS14165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC756_RS14165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC756_RS14165	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC756_RS14170	COG1105	Belongs to the carbohydrate kinase PfkB family
IC756_RS14175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS14175	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS14180	COG2814	Major facilitator Superfamily
IC756_RS14195	COG0246	Mannitol dehydrogenase
IC756_RS14200	COG0523	cobalamin synthesis protein
IC756_RS14205	COG0671	phosphoesterase, PA-phosphatase related
IC756_RS14210	COG0791	NLP P60 protein
IC756_RS14215	COG2200	EAL domain
IC756_RS14220	COG4166	transmembrane transport
IC756_RS14225	COG4174	ABC transporter (Permease)
IC756_RS14230	COG4239	(ABC) transporter, permease
IC756_RS14235	COG4172	Belongs to the ABC transporter superfamily
IC756_RS14245	COG2814	Major facilitator Superfamily
IC756_RS14250	COG1187	pseudouridine synthase activity
IC756_RS14255	COG1061	Type III restriction enzyme res subunit
IC756_RS14275	COG3083	sulfuric ester hydrolase activity
IC756_RS14285	COG0582	viral genome integration into host DNA
IC756_RS14355	COG4220	transposase activity
IC756_RS14365	COG3468	outer membrane autotransporter barrel domain protein
IC756_RS14370	COG2197	response regulator
IC756_RS14375	COG4235	cytochrome complex assembly
IC756_RS14375	COG3088	subunit of a heme lyase
IC756_RS14380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IC756_RS14385	COG1138	Cytochrome C-type biogenesis protein
IC756_RS14395	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IC756_RS14400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IC756_RS14405	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IC756_RS14415	COG3005	denitrification pathway
IC756_RS14420	COG3043	anaerobic respiration
IC756_RS14425	COG0348	domain, Protein
IC756_RS14430	COG0437	4 iron, 4 sulfur cluster binding
IC756_RS14440	COG3062	negative regulation of establishment of protein localization
IC756_RS14445	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS14445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS14460	COG4615	Cyclic peptide transporter
IC756_RS14465	COG3145	DNA-N1-methyladenine dioxygenase activity
IC756_RS14470	COG2169	Transcriptional regulator
IC756_RS14470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC756_RS14475	COG1477	protein flavinylation
IC756_RS14480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IC756_RS14485	COG0642	Histidine kinase
IC756_RS14485	COG2198	Histidine kinase
IC756_RS14490	COG2197	response regulator
IC756_RS14495	COG0784	Response regulator, receiver
IC756_RS14495	COG2205	protein histidine kinase activity
IC756_RS14500	COG3852	Histidine kinase
IC756_RS14510	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC756_RS14515	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC756_RS14520	COG2031	fatty acid transporter
IC756_RS14525	COG0183	Belongs to the thiolase family
IC756_RS14530	COG4676	Protein conserved in bacteria
IC756_RS14535	COG5445	Predicted secreted protein (DUF2300)
IC756_RS14540	COG2373	Large extracellular alpha-helical protein
IC756_RS14545	COG3234	Protein of unknown function (DUF1175)
IC756_RS14550	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
IC756_RS14555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IC756_RS14565	COG3468	outer membrane autotransporter barrel domain protein
IC756_RS14570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC756_RS14575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC756_RS14580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC756_RS14585	COG3642	lipopolysaccharide core region biosynthetic process
IC756_RS14590	COG2814	Major facilitator Superfamily
IC756_RS14595	COG0583	DNA-binding transcription factor activity
IC756_RS14605	COG0584	glycerophosphoryl diester phosphodiesterase
IC756_RS14610	COG2271	Major facilitator Superfamily
IC756_RS14615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IC756_RS14625	COG0247	lactate metabolic process
IC756_RS14630	COG5464	transposase or invertase
IC756_RS14645	COG2271	Major facilitator Superfamily
IC756_RS14650	COG0675	Transposase, IS605 OrfB family
IC756_RS14720	COG0318	PFAM AMP-dependent synthetase and ligase
IC756_RS14730	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IC756_RS14745	COG1169	isochorismate synthase
IC756_RS14750	COG4575	ribosome binding
IC756_RS14755	COG2153	protein acetylation
IC756_RS14765	COG5160	protein modification by small protein removal
IC756_RS14770	COG2234	aminopeptidase activity
IC756_RS14785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC756_RS14790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC756_RS14800	COG0839	Belongs to the complex I subunit 6 family
IC756_RS14815	COG1034	ATP synthesis coupled electron transport
IC756_RS14820	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC756_RS14825	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IC756_RS14845	COG0583	DNA-binding transcription factor activity
IC756_RS14850	COG0436	Aminotransferase
IC756_RS14860	COG0490	domain, Protein
IC756_RS14860	COG0471	metal ion transport
IC756_RS14865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC756_RS14880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC756_RS14885	COG0280	phosphate acetyltransferase
IC756_RS14885	COG0857	belongs to the CobB CobQ family
IC756_RS14890	COG1288	antiporter activity
IC756_RS14895	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IC756_RS14900	COG0622	Phosphoesterase
IC756_RS14905	COG0625	glutathione transferase activity
IC756_RS14910	COG0625	glutathione transferase activity
IC756_RS14915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IC756_RS14920	COG1090	epimerase
IC756_RS14925	COG5464	transposase or invertase
IC756_RS14930	COG4598	ABC transporter
IC756_RS14935	COG4160	amino acid transport
IC756_RS14940	COG4215	(ABC) transporter
IC756_RS14945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC756_RS14950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC756_RS14955	COG0163	prenyltransferase activity
IC756_RS14960	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IC756_RS14965	COG1286	toxin biosynthetic process
IC756_RS14970	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IC756_RS14975	COG0285	dihydrofolate synthase activity
IC756_RS14985	COG0586	Pfam SNARE associated Golgi protein
IC756_RS14995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IC756_RS15010	COG2814	Major facilitator Superfamily
IC756_RS15015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IC756_RS15030	COG3101	peptidyl-lysine hydroxylation
IC756_RS15035	COG0730	response to heat
IC756_RS15050	COG2890	protein-(glutamine-N5) methyltransferase activity
IC756_RS15065	COG3539	Fimbrial protein
IC756_RS15070	COG3539	Fimbrial protein
IC756_RS15075	COG3539	Fimbrial protein
IC756_RS15080	COG3121	Chaperone
IC756_RS15085	COG3188	usher protein
IC756_RS15090	COG3539	Fimbrial protein
IC756_RS15095	COG2062	phosphohistidine phosphatase, SixA
IC756_RS15110	COG3691	Protein conserved in bacteria
IC756_RS15115	COG2067	long-chain fatty acid transport protein
IC756_RS15125	COG2853	Lipoprotein
IC756_RS15130	COG2116	formate transmembrane transporter activity
IC756_RS15175	COG0477	Major facilitator Superfamily
IC756_RS15180	COG1566	PFAM secretion protein HlyD family protein
IC756_RS15185	COG2197	response regulator
IC756_RS15190	COG0784	Response regulator, receiver
IC756_RS15190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC756_RS15190	COG2198	Histidine kinase
IC756_RS15190	COG2205	protein histidine kinase activity
IC756_RS15195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC756_RS15200	COG0679	Auxin Efflux Carrier
IC756_RS15205	COG0028	Belongs to the TPP enzyme family
IC756_RS15230	COG1560	Kdo2-lipid A biosynthetic process
IC756_RS15240	COG0436	Aminotransferase
IC756_RS15245	COG3275	phosphorelay sensor kinase activity
IC756_RS15250	COG3279	Response regulator of the LytR AlgR family
IC756_RS15255	COG2207	Transcriptional regulator
IC756_RS15265	COG1363	Peptidase, m42
IC756_RS15270	COG0006	proline dipeptidase activity
IC756_RS15275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC756_RS15280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC756_RS15305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IC756_RS15310	COG2200	EAL domain
IC756_RS15310	COG2199	diguanylate cyclase activity
IC756_RS15325	COG3415	Transposase
IC756_RS15330	COG3415	Transposase
IC756_RS15365	COG0583	DNA-binding transcription factor activity
IC756_RS15370	COG0385	Bile acid
IC756_RS15375	COG3530	Putative quorum-sensing-regulated virulence factor
IC756_RS15395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC756_RS15400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS15405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC756_RS15410	COG2190	(PTS) system
IC756_RS15425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC756_RS15430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC756_RS15435	COG4208	sulfate ABC transporter
IC756_RS15440	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC756_RS15445	COG4150	thiosulfate binding
IC756_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS15465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS15465	COG1263	PTS System
IC756_RS15470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC756_RS15475	COG2837	iron assimilation
IC756_RS15495	COG0860	N-Acetylmuramoyl-L-alanine amidase
IC756_RS15505	COG2207	Transcriptional regulator
IC756_RS15510	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IC756_RS15515	COG4816	utilization protein
IC756_RS15525	COG4303	Ethanolamine ammonia lyase large subunit
IC756_RS15530	COG4819	ethanolamine utilization protein
IC756_RS15535	COG3192	ethanolamine utilization protein
IC756_RS15540	COG1454	alcohol dehydrogenase
IC756_RS15545	COG4820	ethanolamine utilization protein (EutJ)
IC756_RS15550	COG1012	belongs to the aldehyde dehydrogenase family
IC756_RS15555	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IC756_RS15560	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IC756_RS15565	COG0280	phosphate acetyltransferase
IC756_RS15570	COG4812	Cobalamin adenosyltransferase
IC756_RS15575	COG4766	ethanolamine catabolic process
IC756_RS15580	COG4917	ethanolamine utilization protein
IC756_RS15585	COG4810	utilization protein
IC756_RS15590	COG0280	phosphate acetyltransferase
IC756_RS15590	COG0281	malic enzyme
IC756_RS15595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC756_RS15600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC756_RS15605	COG5342	invasion associated locus B
IC756_RS15615	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS15615	COG0493	'glutamate synthase
IC756_RS15620	COG3850	Histidine kinase
IC756_RS15625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC756_RS15635	COG1393	Belongs to the ArsC family
IC756_RS15650	COG0400	carboxylic ester hydrolase activity
IC756_RS15660	COG2321	neutral zinc metallopeptidase
IC756_RS15670	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IC756_RS15680	COG2716	regulation of RNA biosynthetic process
IC756_RS15685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC756_RS15690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS15695	COG0651	ATP synthesis coupled electron transport
IC756_RS15700	COG0650	Formate hydrogenlyase subunit 4
IC756_RS15705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC756_RS15710	COG4237	Hydrogenase 4 membrane
IC756_RS15715	COG0651	ATP synthesis coupled electron transport
IC756_RS15725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC756_RS15730	COG3260	NADH ubiquinone oxidoreductase 20
IC756_RS15740	COG3604	Transcriptional regulator
IC756_RS15745	COG2116	formate transmembrane transporter activity
IC756_RS15750	COG0628	permease
IC756_RS15755	COG4783	chaperone-mediated protein folding
IC756_RS15760	COG1393	Belongs to the ArsC family
IC756_RS15770	COG2233	PERMEase
IC756_RS15785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC756_RS15790	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IC756_RS15795	COG0248	Ppx GppA phosphatase
IC756_RS15800	COG2200	EAL domain
IC756_RS15815	COG3133	Outer membrane lipoprotein
IC756_RS15835	COG0516	GMP reductase activity
IC756_RS15835	COG0517	IMP dehydrogenase activity
IC756_RS15860	COG1645	bacterial-type flagellum-dependent swarming motility
IC756_RS15875	COG2976	Protein conserved in bacteria
IC756_RS15905	COG4953	penicillin-binding protein 1C
IC756_RS15910	COG2373	Large extracellular alpha-helical protein
IC756_RS15915	COG2897	thiosulfate sulfurtransferase activity
IC756_RS15930	COG2975	iron-sulfur cluster assembly
IC756_RS15935	COG0633	Ferredoxin
IC756_RS15955	COG0822	iron-sulfur transferase activity
IC756_RS15975	COG0483	inositol monophosphate 1-phosphatase activity
IC756_RS15980	COG1073	alpha beta
IC756_RS15985	COG3711	transcriptional antiterminator
IC756_RS15990	COG2814	Major facilitator Superfamily
IC756_RS15995	COG0583	DNA-binding transcription factor activity
IC756_RS16000	COG4638	Rieske (2fe-2S)
IC756_RS16025	COG2259	Doxx family
IC756_RS16030	COG2017	converts alpha-aldose to the beta-anomer
IC756_RS16035	COG1063	alcohol dehydrogenase
IC756_RS16040	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC756_RS16045	COG1129	ABC transporter
IC756_RS16050	COG1879	ABC-type sugar transport system periplasmic component
IC756_RS16055	COG0457	Tetratricopeptide repeat
IC756_RS16060	COG1940	carbohydrate kinase activity
IC756_RS16070	COG1017	nitric oxide dioxygenase activity
IC756_RS16070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC756_RS16075	COG0347	Belongs to the P(II) protein family
IC756_RS16080	COG2204	response regulator
IC756_RS16085	COG3170	Tfp pilus assembly protein FimV
IC756_RS16090	COG2205	protein histidine kinase activity
IC756_RS16095	COG0047	phosphoribosylformylglycinamidine synthase activity
IC756_RS16095	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC756_RS16105	COG0590	tRNA wobble adenosine to inosine editing
IC756_RS16110	COG0560	Phosphoserine phosphatase
IC756_RS16115	COG1737	Transcriptional regulator
IC756_RS16120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS16135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC756_RS16155	COG0681	Belongs to the peptidase S26 family
IC756_RS16165	COG3086	response to oxidative stress
IC756_RS16170	COG3026	antisigma factor binding
IC756_RS16175	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IC756_RS16180	COG1595	DNA-templated transcription, initiation
IC756_RS16190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IC756_RS16200	COG0513	Belongs to the DEAD box helicase family
IC756_RS16210	COG0583	DNA-binding transcription factor activity
IC756_RS16230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC756_RS16235	COG3118	belongs to the thioredoxin family
IC756_RS16240	COG3148	PFAM DTW domain containing protein
IC756_RS16245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC756_RS16245	COG0045	succinate-CoA ligase (ADP-forming) activity
IC756_RS16245	COG1042	CoA-binding domain protein
IC756_RS16250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC756_RS16255	COG5544	Lipoprotein
IC756_RS16260	COG0477	Major facilitator Superfamily
IC756_RS16285	COG0542	response to heat
IC756_RS16295	COG0564	pseudouridine synthase activity
IC756_RS16300	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC756_RS16305	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IC756_RS16315	COG1605	Chorismate mutase
IC756_RS16315	COG0077	Prephenate dehydratase
IC756_RS16320	COG1605	Chorismate mutase
IC756_RS16320	COG0287	Prephenate dehydrogenase
IC756_RS16325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC756_RS16340	COG2199	diguanylate cyclase activity
IC756_RS16345	COG2885	chlorophyll binding
IC756_RS16370	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC756_RS16375	COG4137	Cytochrome C assembly protein
IC756_RS16380	COG4536	flavin adenine dinucleotide binding
IC756_RS16395	COG0497	DNA recombination
IC756_RS16400	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC756_RS16410	COG2867	negative regulation of translational initiation
IC756_RS16425	COG0582	viral genome integration into host DNA
IC756_RS16495	COG3732	PTS system glucitol sorbitol-specific
IC756_RS16510	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IC756_RS16515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC756_RS16525	COG1263	PTS System
IC756_RS16525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS16525	COG2190	(PTS) system
IC756_RS16540	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC756_RS16570	COG3468	outer membrane autotransporter barrel domain protein
IC756_RS16600	COG0366	Alpha amylase catalytic
IC756_RS16610	COG0579	oxidoreductase
IC756_RS16615	COG1012	belongs to the aldehyde dehydrogenase family
IC756_RS16620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC756_RS16625	COG1113	amino acid transport
IC756_RS16630	COG1802	Transcriptional regulator
IC756_RS16635	COG1652	LysM domain
IC756_RS16640	COG0401	homolog of Blt101
IC756_RS16645	COG0640	Transcriptional regulator
IC756_RS16650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IC756_RS16655	COG2916	Histone family protein nucleoid-structuring protein H-NS
IC756_RS16670	COG4575	ribosome binding
IC756_RS16675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC756_RS16680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC756_RS16685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC756_RS16695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC756_RS16700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC756_RS16705	COG4175	Glycine betaine
IC756_RS16710	COG4176	ABC-type proline glycine betaine transport system permease component
IC756_RS16715	COG2113	Glycine betaine
IC756_RS16720	COG2814	Major facilitator Superfamily
IC756_RS16725	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC756_RS16735	COG1846	Transcriptional regulator
IC756_RS16740	COG1566	PFAM secretion protein HlyD family protein
IC756_RS16745	COG2814	Major facilitator Superfamily
IC756_RS16760	COG1238	metal cluster binding
IC756_RS16765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC756_RS16795	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IC756_RS16815	COG1546	Belongs to the CinA family
IC756_RS16820	COG2951	lytic endotransglycosylase activity
IC756_RS16825	COG3730	PTS system glucitol sorbitol-specific
IC756_RS16830	COG3732	PTS system glucitol sorbitol-specific
IC756_RS16840	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS16845	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS16850	COG1349	DNA-binding transcription factor activity
IC756_RS16875	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IC756_RS16880	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS16885	COG1609	Transcriptional regulator
IC756_RS16890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS16890	COG1263	PTS System
IC756_RS16895	COG2723	6-phospho-beta-galactosidase activity
IC756_RS16900	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IC756_RS16910	COG3260	NADH ubiquinone oxidoreductase 20
IC756_RS16915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC756_RS16920	COG3261	NADH dehydrogenase
IC756_RS16920	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IC756_RS16925	COG0650	Formate hydrogenlyase subunit 4
IC756_RS16930	COG0651	ATP synthesis coupled electron transport
IC756_RS16935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS16945	COG0375	protein maturation
IC756_RS16950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IC756_RS16955	COG0298	carbon dioxide binding
IC756_RS16960	COG0409	Hydrogenase expression formation protein
IC756_RS16965	COG0309	Hydrogenase expression formation protein (HypE)
IC756_RS16970	COG3604	Transcriptional regulator
IC756_RS17000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC756_RS17010	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IC756_RS17015	COG0163	prenyltransferase activity
IC756_RS17025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IC756_RS17030	COG4942	peptidase
IC756_RS17030	COG1388	LysM domain
IC756_RS17085	COG2234	aminopeptidase activity
IC756_RS17090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC756_RS17110	COG1857	crispr-associated protein
IC756_RS17125	COG1203	CRISPR-associated helicase, Cas3
IC756_RS17150	COG0720	synthase
IC756_RS17155	COG0644	oxidoreductase
IC756_RS17160	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC756_RS17165	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IC756_RS17170	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IC756_RS17175	COG2086	electron transfer activity
IC756_RS17180	COG0477	Major facilitator Superfamily
IC756_RS17185	COG0277	FAD linked oxidase domain protein
IC756_RS17190	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS17195	COG2223	nitrite transmembrane transporter activity
IC756_RS17200	COG1070	Carbohydrate kinase
IC756_RS17205	COG0602	queuosine metabolic process
IC756_RS17215	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC756_RS17225	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC756_RS17240	COG3956	TIGRFAM MazG family protein
IC756_RS17245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC756_RS17255	COG3850	Histidine kinase
IC756_RS17255	COG3437	response regulator, receiver
IC756_RS17255	COG4999	Histidine kinase
IC756_RS17255	COG2205	protein histidine kinase activity
IC756_RS17260	COG4948	Mandelate Racemase Muconate Lactonizing
IC756_RS17265	COG4948	Mandelate Racemase Muconate Lactonizing
IC756_RS17270	COG2271	Major facilitator Superfamily
IC756_RS17275	COG0716	FMN binding
IC756_RS17280	COG0564	pseudouridine synthase activity
IC756_RS17285	COG3098	single-species biofilm formation
IC756_RS17300	COG1611	Belongs to the LOG family
IC756_RS17305	COG0814	amino acid
IC756_RS17310	COG1760	l-serine dehydratase
IC756_RS17320	COG1454	alcohol dehydrogenase
IC756_RS17325	COG0235	Class ii aldolase
IC756_RS17330	COG0738	Major facilitator superfamily
IC756_RS17340	COG1070	Carbohydrate kinase
IC756_RS17350	COG1349	DNA-binding transcription factor activity
IC756_RS17360	COG2363	Small membrane protein
IC756_RS17365	COG0583	DNA-binding transcription factor activity
IC756_RS17375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC756_RS17380	COG2166	iron-sulfur cluster assembly
IC756_RS17385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC756_RS17390	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IC756_RS17405	COG0860	N-Acetylmuramoyl-L-alanine amidase
IC756_RS17410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC756_RS17410	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC756_RS17415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC756_RS17420	COG1074	ATP-dependent DNA helicase activity
IC756_RS17430	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC756_RS17435	COG4967	type IV pilus modification protein PilV
IC756_RS17445	COG4795	General secretion pathway protein
IC756_RS17450	COG2165	general secretion pathway protein
IC756_RS17465	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
IC756_RS17480	COG0861	Integral membrane protein TerC family
IC756_RS17490	COG0667	Aldo Keto reductase
IC756_RS17505	COG1609	Transcriptional regulator
IC756_RS17515	COG0583	DNA-binding transcription factor activity
IC756_RS17520	COG1794	racemase activity, acting on amino acids and derivatives
IC756_RS17525	COG2814	Major facilitator Superfamily
IC756_RS17530	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS17540	COG0183	Belongs to the thiolase family
IC756_RS17545	COG0814	amino acid
IC756_RS17550	COG2771	luxR family
IC756_RS17555	COG3710	Transcriptional regulator
IC756_RS17580	COG0457	Tetratricopeptide repeat
IC756_RS17585	COG3710	Transcriptional regulator
IC756_RS17585	COG0457	Tetratricopeptide repeat
IC756_RS17595	COG0741	lytic transglycosylase activity
IC756_RS17600	COG2197	response regulator
IC756_RS17700	COG2207	Transcriptional regulator
IC756_RS17710	COG3387	PFAM Glycoside hydrolase 15-related
IC756_RS17720	COG4942	peptidase
IC756_RS17725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC756_RS17730	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IC756_RS17735	COG2080	2 iron, 2 sulfur cluster binding
IC756_RS17740	COG3829	transcription factor binding
IC756_RS17745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IC756_RS17750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC756_RS17755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IC756_RS17765	COG0549	Belongs to the carbamate kinase family
IC756_RS17770	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IC756_RS17770	COG3608	succinylglutamate desuccinylase aspartoacylase
IC756_RS17775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC756_RS17780	COG2068	MobA-Related Protein
IC756_RS17785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS17785	COG0493	'glutamate synthase
IC756_RS17790	COG0402	S-adenosylhomocysteine deaminase activity
IC756_RS17795	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IC756_RS17800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC756_RS17800	COG2080	2 iron, 2 sulfur cluster binding
IC756_RS17805	COG2233	PERMEase
IC756_RS17810	COG0402	S-adenosylhomocysteine deaminase activity
IC756_RS17815	COG2252	PERMEase
IC756_RS17820	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS17825	COG0493	'glutamate synthase
IC756_RS17825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS17830	COG2233	PERMEase
IC756_RS17850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IC756_RS17860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC756_RS17865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC756_RS17870	COG4974	Belongs to the 'phage' integrase family
IC756_RS17875	COG0716	FMN binding
IC756_RS17885	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC756_RS17895	COG1272	protein, Hemolysin III
IC756_RS17905	COG2723	6-phospho-beta-galactosidase activity
IC756_RS17910	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS17935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC756_RS17940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC756_RS17945	COG0006	proline dipeptidase activity
IC756_RS17965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC756_RS17975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC756_RS17995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IC756_RS17995	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IC756_RS18000	COG1703	isobutyryl-CoA mutase activity
IC756_RS18005	COG1024	Enoyl-CoA hydratase
IC756_RS18010	COG0427	acetyl-CoA hydrolase
IC756_RS18015	COG0583	DNA-binding transcription factor activity
IC756_RS18020	COG2968	Membrane
IC756_RS18025	COG1279	arginine transmembrane transporter activity
IC756_RS18030	COG0668	transmembrane transport
IC756_RS18035	COG0191	fructose-bisphosphate aldolase activity
IC756_RS18050	COG1072	(Pantothenic acid kinase))
IC756_RS18055	COG3722	fumarate hydratase activity
IC756_RS18060	COG1494	fructose-1,6-bisphosphatase
IC756_RS18065	COG1063	alcohol dehydrogenase
IC756_RS18070	COG2213	PTS system mannitol-specific
IC756_RS18075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS18080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC756_RS18085	COG0501	Belongs to the peptidase M48B family
IC756_RS18095	COG1166	arginine decarboxylase activity
IC756_RS18115	COG2814	Major facilitator Superfamily
IC756_RS18125	COG2356	endonuclease I
IC756_RS18130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC756_RS18135	COG0189	ligase activity
IC756_RS18150	COG2805	Type II/IV secretion system protein
IC756_RS18155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IC756_RS18160	COG0762	integral membrane protein
IC756_RS18175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC756_RS18185	COG0252	asparaginase activity
IC756_RS18195	COG3171	Protein conserved in bacteria
IC756_RS18205	COG1194	a g-specific adenine glycosylase
IC756_RS18220	COG2211	Major facilitator Superfamily
IC756_RS18225	COG1982	Orn Lys Arg decarboxylase major
IC756_RS18230	COG1811	Na channel or pump
IC756_RS18260	COG4372	Transposase
IC756_RS18265	COG3436	PFAM IS66 Orf2 family protein
IC756_RS18320	COG3468	outer membrane autotransporter barrel domain protein
IC756_RS18340	COG2003	Belongs to the UPF0758 family
IC756_RS18375	COG2200	EAL domain
IC756_RS18375	COG2771	luxR family
IC756_RS18435	COG2089	acid synthase
IC756_RS18455	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IC756_RS18485	COG2165	general secretion pathway protein
IC756_RS18490	COG1459	type II secretion system
IC756_RS18495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC756_RS18515	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IC756_RS18525	COG1620	l-lactate permease
IC756_RS18530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC756_RS18535	COG3193	protein, possibly involved in utilization of glycolate and propanediol
IC756_RS18540	COG0247	lactate metabolic process
IC756_RS18545	COG0277	FAD linked oxidase domain protein
IC756_RS18550	COG0277	FAD linked oxidase domain protein
IC756_RS18555	COG2186	Transcriptional regulator
IC756_RS18560	COG0456	acetyltransferase
IC756_RS18565	COG0318	PFAM AMP-dependent synthetase and ligase
IC756_RS18575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC756_RS18580	COG0156	8-amino-7-oxononanoate synthase activity
IC756_RS18590	COG0795	lipopolysaccharide-transporting ATPase activity
IC756_RS18595	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IC756_RS18605	COG2244	polysaccharide biosynthetic process
IC756_RS18610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IC756_RS18615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IC756_RS18620	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IC756_RS18625	COG0306	phosphate transporter
IC756_RS18630	COG0754	glutathionylspermidine amidase activity
IC756_RS18635	COG0625	glutathione transferase activity
IC756_RS18640	COG0298	carbon dioxide binding
IC756_RS18650	COG1773	rubredoxin
IC756_RS18655	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IC756_RS18660	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IC756_RS18665	COG5557	Pfam Polysulphide reductase, NrfD
IC756_RS18670	COG0437	4 iron, 4 sulfur cluster binding
IC756_RS18675	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IC756_RS18690	COG0667	Aldo Keto reductase
IC756_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS18705	COG0848	biopolymer transport protein
IC756_RS18710	COG0811	peptide transport
IC756_RS18715	COG0626	cystathionine gamma-synthase activity
IC756_RS18720	COG0586	Pfam SNARE associated Golgi protein
IC756_RS18725	COG2207	Transcriptional regulator
IC756_RS18730	COG1979	alcohol dehydrogenase
IC756_RS18735	COG0656	L-ascorbic acid biosynthetic process
IC756_RS18745	COG4238	major outer membrane lipoprotein
IC756_RS18750	COG1032	radical SAM domain protein
IC756_RS18755	COG2132	Multicopper oxidase
IC756_RS18760	COG0204	Acyl-transferase
IC756_RS18765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IC756_RS18770	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC756_RS18775	COG3111	PFAM Bacterial OB fold (BOF) protein
IC756_RS18780	COG0745	RESPONSE REGULATOR receiver
IC756_RS18785	COG0642	Histidine kinase
IC756_RS18790	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC756_RS18795	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC756_RS18800	COG1737	Transcriptional regulator
IC756_RS18810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC756_RS18815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC756_RS18820	COG1120	ATPase activity
IC756_RS18825	COG4774	siderophore transport
IC756_RS18830	COG0187	DNA topoisomerase II activity
IC756_RS18835	COG3150	esterase
IC756_RS18840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IC756_RS18845	COG3151	Protein conserved in bacteria
IC756_RS18850	COG0494	nUDIX hydrolase
IC756_RS18855	COG1538	Outer membrane efflux protein
IC756_RS18865	COG0754	glutathionylspermidine amidase activity
IC756_RS18875	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC756_RS18885	COG3384	dioxygenase
IC756_RS18915	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC756_RS18920	COG2268	Band 7 protein
IC756_RS18945	COG3025	triphosphatase activity
IC756_RS18950	COG4991	sh3 domain protein
IC756_RS18965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IC756_RS18980	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC756_RS18985	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC756_RS19000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IC756_RS19005	COG0358	DNA primase activity
IC756_RS19010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IC756_RS19025	COG2375	cellular response to nickel ion
IC756_RS19030	COG1695	Transcriptional regulator
IC756_RS19035	COG0840	transmembrane signaling receptor activity
IC756_RS19045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC756_RS19050	COG1609	Transcriptional regulator
IC756_RS19055	COG3250	beta-galactosidase activity
IC756_RS19060	COG2731	YhcH YjgK YiaL family protein
IC756_RS19065	COG0531	amino acid
IC756_RS19075	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IC756_RS19075	COG3408	Glycogen debranching enzyme
IC756_RS19080	COG1902	pentaerythritol trinitrate reductase activity
IC756_RS19080	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC756_RS19085	COG5499	transcription regulator containing HTH domain
IC756_RS19090	COG4680	protein conserved in bacteria
IC756_RS19100	COG1451	nucleotide metabolic process
IC756_RS19105	COG2949	membrane
IC756_RS19110	COG0673	inositol 2-dehydrogenase activity
IC756_RS19115	COG0861	Integral membrane protein TerC family
IC756_RS19120	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IC756_RS19130	COG2721	sulfolactate sulfo-lyase activity
IC756_RS19140	COG2271	Major facilitator Superfamily
IC756_RS19145	COG2186	Transcriptional regulator
IC756_RS19150	COG0586	Pfam SNARE associated Golgi protein
IC756_RS19160	COG1422	Protein of unknown function (DUF1090)
IC756_RS19165	COG4575	ribosome binding
IC756_RS19170	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IC756_RS19180	COG2259	Doxx family
IC756_RS19185	COG0435	Glutathione S-transferase
IC756_RS19190	COG3152	Membrane
IC756_RS19195	COG3152	Membrane
IC756_RS19200	COG0583	DNA-binding transcription factor activity
IC756_RS19205	COG1741	Belongs to the pirin family
IC756_RS19220	COG0814	amino acid
IC756_RS19225	COG1760	l-serine dehydratase
IC756_RS19230	COG0251	oxidation-reduction process
IC756_RS19235	COG1882	Formate acetyltransferase
IC756_RS19240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC756_RS19250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC756_RS19255	COG0583	DNA-binding transcription factor activity
IC756_RS19280	COG1929	Belongs to the glycerate kinase type-1 family
IC756_RS19285	COG2084	Dehydrogenase
IC756_RS19295	COG2271	Major facilitator Superfamily
IC756_RS19300	COG2721	sulfolactate sulfo-lyase activity
IC756_RS19305	COG2002	toxin-antitoxin pair type II binding
IC756_RS19315	COG1349	DNA-binding transcription factor activity
IC756_RS19325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS19335	COG3716	PTS system mannose fructose sorbose family IID component
IC756_RS19340	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS19345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IC756_RS19350	COG2222	sugar isomerase
IC756_RS19360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC756_RS19365	COG3715	PTS system
IC756_RS19370	COG3716	PTS system mannose fructose sorbose family IID component
IC756_RS19375	COG0363	glucosamine-6-phosphate deaminase activity
IC756_RS19380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IC756_RS19400	COG2823	Periplasmic or secreted lipoprotein
IC756_RS19405	COG0701	Predicted permease
IC756_RS19410	COG0702	epimerase
IC756_RS19415	COG0693	protein deglycase activity
IC756_RS19430	COG3153	acetyltransferase
IC756_RS19435	COG3154	lipid carrier protein
IC756_RS19440	COG0826	peptidase U32
IC756_RS19445	COG0826	peptidase U32
IC756_RS19450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC756_RS19455	COG3034	peptidoglycan biosynthetic process
IC756_RS19465	COG0814	amino acid
IC756_RS19470	COG0513	Belongs to the DEAD box helicase family
IC756_RS19510	COG0195	Participates in both transcription termination and antitermination
IC756_RS19530	COG2194	sulfuric ester hydrolase activity
IC756_RS19540	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IC756_RS19550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC756_RS19555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC756_RS19565	COG1534	Rna-binding protein
IC756_RS19570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC756_RS19575	COG2027	D-alanyl-D-alanine carboxypeptidase
IC756_RS19585	COG0697	spore germination
IC756_RS19600	COG0142	geranyltranstransferase activity
IC756_RS19605	COG3423	Transcriptional regulator
IC756_RS19615	COG5007	Belongs to the BolA IbaG family
IC756_RS19620	COG3113	response to antibiotic
IC756_RS19625	COG2854	intermembrane phospholipid transfer
IC756_RS19630	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC756_RS19635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC756_RS19640	COG1127	ABC transporter
IC756_RS19645	COG0530	calcium, potassium:sodium antiporter activity
IC756_RS19650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC756_RS19650	COG0517	IMP dehydrogenase activity
IC756_RS19655	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC756_RS19660	COG3117	lipopolysaccharide transmembrane transporter activity
IC756_RS19665	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC756_RS19670	COG1137	ATPase activity
IC756_RS19675	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IC756_RS19680	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IC756_RS19695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS19700	COG0515	serine threonine protein kinase
IC756_RS19710	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IC756_RS19715	COG0784	Response regulator, receiver
IC756_RS19715	COG5002	protein histidine kinase activity
IC756_RS19715	COG2198	Histidine kinase
IC756_RS19720	COG1242	4 iron, 4 sulfur cluster binding
IC756_RS19725	COG0069	glutamate synthase activity
IC756_RS19725	COG0070	glutamate synthase
IC756_RS19725	COG0067	glutamate synthase
IC756_RS19730	COG0493	'glutamate synthase
IC756_RS19740	COG2731	YhcH YjgK YiaL family protein
IC756_RS19770	COG3069	C4-dicarboxylate transmembrane transporter activity
IC756_RS19775	COG2969	positive regulation of protein catabolic process
IC756_RS19780	COG0625	glutathione transferase activity
IC756_RS19795	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC756_RS19800	COG3105	Protein conserved in bacteria
IC756_RS19805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC756_RS19810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC756_RS19830	COG2732	(Barnase) inhibitor
IC756_RS19850	COG0583	DNA-binding transcription factor activity
IC756_RS19855	COG0312	modulator of DNA gyrase
IC756_RS19860	COG3164	Protein of unknown function
IC756_RS19865	COG1530	ribonuclease E activity
IC756_RS19875	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC756_RS19880	COG1792	Involved in formation and maintenance of cell shape
IC756_RS19885	COG1077	Cell shape determining protein MreB Mrl
IC756_RS19890	COG2199	diguanylate cyclase activity
IC756_RS19890	COG2200	EAL domain
IC756_RS19895	COG0604	alcohol dehydrogenase
IC756_RS19905	COG0511	ligase activity, forming carbon-carbon bonds
IC756_RS19910	COG0439	Biotin carboxylase
IC756_RS19915	COG3924	membrane
IC756_RS19920	COG4145	pantothenate transmembrane transporter activity
IC756_RS19930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC756_RS19940	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IC756_RS19950	COG1309	transcriptional regulator
IC756_RS19955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC756_RS19960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC756_RS19970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC756_RS19975	COG4597	amino acid ABC transporter
IC756_RS19980	COG0765	amino acid transport
IC756_RS19985	COG1126	abc transporter atp-binding protein
IC756_RS20025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC756_RS20045	COG0551	DNA topoisomerase type I activity
IC756_RS20055	COG0758	DNA mediated transformation
IC756_RS20075	COG0569	domain protein
IC756_RS20085	COG3036	rescue of stalled ribosome
IC756_RS20090	COG0789	Transcriptional regulator
IC756_RS20130	COG0201	protein transport
IC756_RS20220	COG0089	rRNA binding
IC756_RS20290	COG2964	Protein conserved in bacteria
IC756_RS20295	COG0545	Peptidyl-prolyl cis-trans isomerase
IC756_RS20305	COG1047	Peptidyl-prolyl cis-trans
IC756_RS20310	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC756_RS20325	COG0488	(ABC) transporter
IC756_RS20330	COG0429	hydrolase of the alpha beta-hydrolase fold
IC756_RS20340	COG3954	Phosphoribulokinase
IC756_RS20345	COG1765	OsmC-like protein
IC756_RS20350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC756_RS20355	COG1289	transmembrane transporter activity
IC756_RS20360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC756_RS20365	COG0512	Glutamine amidotransferase of anthranilate synthase
IC756_RS20370	COG2184	nucleotidyltransferase activity
IC756_RS20380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC756_RS20390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC756_RS20395	COG2146	nitrite reductase [NAD(P)H] activity
IC756_RS20400	COG2116	formate transmembrane transporter activity
IC756_RS20415	COG0626	cystathionine gamma-synthase activity
IC756_RS20430	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IC756_RS20435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IC756_RS20440	COG3457	Alanine racemase
IC756_RS20450	COG2188	Transcriptional regulator
IC756_RS20455	COG0180	Tryptophanyl-tRNA synthetase
IC756_RS20465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC756_RS20470	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IC756_RS20475	COG3266	domain, Protein
IC756_RS20490	COG4796	Type ii and iii secretion system protein
IC756_RS20505	COG3166	PFAM Fimbrial assembly family protein
IC756_RS20510	COG4972	Pilus assembly protein
IC756_RS20515	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IC756_RS20520	COG0494	nUDIX hydrolase
IC756_RS20530	COG1011	Hydrolase
IC756_RS20535	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC756_RS20545	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC756_RS20565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC756_RS20570	COG2183	response to ionizing radiation
IC756_RS20575	COG1918	ferrous iron import across plasma membrane
IC756_RS20580	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IC756_RS20590	COG5464	transposase or invertase
IC756_RS20610	COG2610	gluconate transmembrane transporter activity
IC756_RS20615	COG1640	4-alpha-glucanotransferase
IC756_RS20620	COG0058	SHG alpha-glucan phosphorylase activity
IC756_RS20640	COG4650	regulator
IC756_RS20645	COG1349	DNA-binding transcription factor activity
IC756_RS20660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IC756_RS20670	COG3121	Chaperone
IC756_RS20680	COG3539	Fimbrial protein
IC756_RS20685	COG3188	usher protein
IC756_RS20690	COG3121	Chaperone
IC756_RS20700	COG0058	SHG alpha-glucan phosphorylase activity
IC756_RS20720	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IC756_RS20725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IC756_RS20730	COG2095	MarC family integral membrane protein
IC756_RS20735	COG2610	gluconate transmembrane transporter activity
IC756_RS20740	COG3265	gluconokinase activity
IC756_RS20745	COG1609	Transcriptional regulator
IC756_RS20750	COG1741	Belongs to the pirin family
IC756_RS20755	COG0673	inositol 2-dehydrogenase activity
IC756_RS20760	COG1247	-acetyltransferase
IC756_RS20765	COG3157	Type VI secretion system effector, Hcp
IC756_RS20785	COG0405	Gamma-glutamyltransferase
IC756_RS20795	COG0584	glycerophosphoryl diester phosphodiesterase
IC756_RS20810	COG1175	transmembrane transport
IC756_RS20815	COG1653	transport
IC756_RS20820	COG0410	ABC transporter
IC756_RS20825	COG0411	ABC transporter
IC756_RS20830	COG4177	L-phenylalanine transmembrane transporter activity
IC756_RS20835	COG0559	Belongs to the binding-protein-dependent transport system permease family
IC756_RS20840	COG0683	leucine binding
IC756_RS20845	COG0456	acetyltransferase
IC756_RS20855	COG0683	leucine binding
IC756_RS20860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IC756_RS20865	COG2177	Part of the ABC transporter FtsEX involved in
IC756_RS20870	COG2884	Cell division ATP-binding protein ftsE
IC756_RS20875	COG0552	protein localization to endoplasmic reticulum
IC756_RS20880	COG0742	ribosomal rna small subunit methyltransferase
IC756_RS20885	COG3776	membrane
IC756_RS20895	COG3714	YhhN family
IC756_RS20915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IC756_RS20925	COG0477	Major facilitator Superfamily
IC756_RS20930	COG0628	permease
IC756_RS20950	COG0204	Acyl-transferase
IC756_RS20960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC756_RS20980	COG1216	Glycosyl transferase, family 2
IC756_RS21005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IC756_RS21015	COG1028	Short-chain dehydrogenase reductase Sdr
IC756_RS21020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IC756_RS21025	COG2091	lysine biosynthetic process via aminoadipic acid
IC756_RS21030	COG0747	negative chemotaxis
IC756_RS21035	COG0601	transmembrane transport
IC756_RS21040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC756_RS21060	COG2188	Transcriptional regulator
IC756_RS21070	COG3414	Phosphotransferase system galactitol-specific IIB component
IC756_RS21075	COG3775	system Galactitol-specific IIC component
IC756_RS21090	COG0191	fructose-bisphosphate aldolase activity
IC756_RS21095	COG0842	Transport permease protein
IC756_RS21100	COG1129	ABC transporter
IC756_RS21100	COG0842	Transport permease protein
IC756_RS21105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC756_RS21125	COG2081	HI0933 family
IC756_RS21130	COG0306	phosphate transporter
IC756_RS21140	COG0589	response to stress
IC756_RS21145	COG3104	oligopeptide transport
IC756_RS21155	COG0339	signal peptide processing
IC756_RS21160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC756_RS21165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC756_RS21180	COG0640	Transcriptional regulator
IC756_RS21195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IC756_RS21200	COG1393	Belongs to the ArsC family
IC756_RS21220	COG3065	identical protein binding
IC756_RS21225	COG2197	response regulator
IC756_RS21230	COG3720	iron ion transport
IC756_RS21235	COG4771	TonB-dependent receptor
IC756_RS21240	COG4558	Periplasmic binding protein
IC756_RS21250	COG3721	Heme iron utilization protein
IC756_RS21260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC756_RS21270	COG1285	pathogenesis
IC756_RS21285	COG3247	response to pH
IC756_RS21290	COG2771	luxR family
IC756_RS21300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC756_RS21305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC756_RS21310	COG2207	Transcriptional regulator
IC756_RS21315	COG2207	Transcriptional regulator
IC756_RS21320	COG0076	glutamate decarboxylase activity
IC756_RS21325	COG1858	cytochrome C peroxidase
IC756_RS21335	COG2197	response regulator
IC756_RS21340	COG0583	DNA-binding transcription factor activity
IC756_RS21345	COG1295	ribonuclease BN
IC756_RS21350	COG0477	Major facilitator Superfamily
IC756_RS21355	COG2982	Protein involved in outer membrane biogenesis
IC756_RS21360	COG2200	EAL domain
IC756_RS21395	COG0612	Peptidase, M16
IC756_RS21405	COG2200	EAL domain
IC756_RS21405	COG2199	diguanylate cyclase activity
IC756_RS21410	COG3118	belongs to the thioredoxin family
IC756_RS21410	COG0457	Tetratricopeptide repeat
IC756_RS21415	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IC756_RS21420	COG1215	transferase activity, transferring glycosyl groups
IC756_RS21425	COG1215	transferase activity, transferring glycosyl groups
IC756_RS21450	COG2194	sulfuric ester hydrolase activity
IC756_RS21465	COG0814	amino acid
IC756_RS21470	COG4608	Belongs to the ABC transporter superfamily
IC756_RS21475	COG0444	Belongs to the ABC transporter superfamily
IC756_RS21480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC756_RS21485	COG0601	transmembrane transport
IC756_RS21490	COG0747	negative chemotaxis
IC756_RS21505	COG2194	sulfuric ester hydrolase activity
IC756_RS21510	COG2223	nitrite transmembrane transporter activity
IC756_RS21515	COG5571	outer membrane autotransporter
IC756_RS21520	COG2818	Glycosylase
IC756_RS21525	COG0456	acetyltransferase
IC756_RS21530	COG0243	molybdopterin cofactor binding
IC756_RS21535	COG2885	chlorophyll binding
IC756_RS21550	COG2944	sequence-specific DNA binding
IC756_RS21555	COG1278	Cold shock
IC756_RS21580	COG3274	enterobacterial common antigen metabolic process
IC756_RS21585	COG4682	membrane
IC756_RS21590	COG4682	membrane
IC756_RS21595	COG1070	Carbohydrate kinase
IC756_RS21605	COG4213	ABC transporter substrate-binding protein
IC756_RS21615	COG4214	carbohydrate transport
IC756_RS21620	COG2207	Transcriptional regulator
IC756_RS21620	COG1609	Transcriptional regulator
IC756_RS21625	COG2992	FlgJ-related protein
IC756_RS21630	COG0366	Alpha amylase catalytic
IC756_RS21635	COG3977	Valine--pyruvate aminotransferase
IC756_RS21640	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC756_RS21645	COG1414	Transcriptional regulator
IC756_RS21655	COG2731	YhcH YjgK YiaL family protein
IC756_RS21660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IC756_RS21665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IC756_RS21670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IC756_RS21675	COG1070	Carbohydrate kinase
IC756_RS21680	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IC756_RS21685	COG3623	hexulose-6-phosphate isomerase
IC756_RS21690	COG0235	Class ii aldolase
IC756_RS21700	COG2211	Major facilitator Superfamily
IC756_RS21710	COG1598	PFAM Uncharacterised protein family UPF0150
IC756_RS21720	COG1012	belongs to the aldehyde dehydrogenase family
IC756_RS21725	COG1454	alcohol dehydrogenase
IC756_RS21730	COG3276	selenocysteine insertion sequence binding
IC756_RS21740	COG0625	glutathione transferase activity
IC756_RS21745	COG1566	PFAM secretion protein HlyD family protein
IC756_RS21755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC756_RS21755	COG2213	PTS system mannitol-specific
IC756_RS21765	COG3722	fumarate hydratase activity
IC756_RS21785	COG5295	Hep Hag repeat protein
IC756_RS21790	COG1620	l-lactate permease
IC756_RS21795	COG2186	Transcriptional regulator
IC756_RS21805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC756_RS21815	COG1045	serine acetyltransferase
IC756_RS21830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC756_RS21835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IC756_RS21845	COG4942	peptidase
IC756_RS21850	COG2861	carbohydrate metabolic process
IC756_RS21855	COG1216	Glycosyl transferase, family 2
IC756_RS21865	COG0156	8-amino-7-oxononanoate synthase activity
IC756_RS21880	COG0859	PFAM glycosyl transferase family 9
IC756_RS21885	COG0859	PFAM glycosyl transferase family 9
IC756_RS21905	COG3642	lipopolysaccharide core region biosynthetic process
IC756_RS21915	COG0515	serine threonine protein kinase
IC756_RS21920	COG0438	transferase activity, transferring glycosyl groups
IC756_RS21925	COG0859	PFAM glycosyl transferase family 9
IC756_RS21930	COG1519	Transferase
IC756_RS21960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC756_RS21985	COG1561	YicC-like family, N-terminal region
IC756_RS21990	COG3645	SOS response
IC756_RS21995	COG2860	membrane
IC756_RS22005	COG0194	GDP metabolic process
IC756_RS22015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC756_RS22020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC756_RS22025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC756_RS22030	COG0786	glutamate:sodium symporter activity
IC756_RS22035	COG2233	PERMEase
IC756_RS22040	COG2982	Protein involved in outer membrane biogenesis
IC756_RS22045	COG1501	Belongs to the glycosyl hydrolase 31 family
IC756_RS22050	COG2211	Major facilitator Superfamily
IC756_RS22065	COG2814	Major facilitator Superfamily
IC756_RS22070	COG0697	spore germination
IC756_RS22075	COG1464	Belongs to the NlpA lipoprotein family
IC756_RS22085	COG0457	Tetratricopeptide repeat
IC756_RS22110	COG1388	LysM domain
IC756_RS22110	COG2373	Large extracellular alpha-helical protein
IC756_RS22110	COG4932	domain protein
IC756_RS22135	COG2252	PERMEase
IC756_RS22150	COG2271	Major facilitator Superfamily
IC756_RS22155	COG2271	Major facilitator Superfamily
IC756_RS22160	COG3851	Histidine kinase
IC756_RS22165	COG2197	response regulator
IC756_RS22180	COG0440	acetolactate synthase activity
IC756_RS22185	COG0028	Belongs to the TPP enzyme family
IC756_RS22200	COG2814	Major facilitator Superfamily
IC756_RS22205	COG0641	radical SAM
IC756_RS22215	COG2149	membrane
IC756_RS22225	COG3119	arylsulfatase activity
IC756_RS22230	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC756_RS22235	COG2207	Transcriptional regulator
IC756_RS22250	COG2188	Transcriptional regulator
IC756_RS22270	COG5645	(Lipo)protein
IC756_RS22275	COG0823	Involved in the tonB-independent uptake of proteins
IC756_RS22285	COG2271	Major facilitator Superfamily
IC756_RS22295	COG0800	Aldolase
IC756_RS22300	COG3734	2-keto-3-deoxy-galactonokinase
IC756_RS22305	COG2186	Transcriptional regulator
IC756_RS22315	COG0561	phosphatase activity
IC756_RS22320	COG3753	Protein conserved in bacteria
IC756_RS22325	COG0187	DNA topoisomerase II activity
IC756_RS22335	COG0592	DNA-directed DNA polymerase activity
IC756_RS22385	COG0814	amino acid
IC756_RS22400	COG2091	lysine biosynthetic process via aminoadipic acid
IC756_RS22405	COG0431	NADPH-dependent FMN reductase
IC756_RS22410	COG2252	PERMEase
IC756_RS22415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC756_RS22435	COG0704	Plays a role in the regulation of phosphate uptake
IC756_RS22440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC756_RS22445	COG0581	inorganic phosphate transmembrane transporter activity
IC756_RS22450	COG0573	inorganic phosphate transmembrane transporter activity
IC756_RS22455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC756_RS22530	COG3312	ion transport
IC756_RS22545	COG0716	FMN binding
IC756_RS22550	COG1522	sequence-specific DNA binding
IC756_RS22580	COG1129	ABC transporter
IC756_RS22585	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC756_RS22590	COG1879	ABC-type sugar transport system periplasmic component
IC756_RS22595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC756_RS22600	COG1609	Transcriptional regulator
IC756_RS22605	COG0477	Major facilitator Superfamily
IC756_RS22610	COG2186	Transcriptional regulator
IC756_RS22650	COG3085	chromosome segregation
IC756_RS22655	COG0606	chelatase, subunit chli
IC756_RS22675	COG3978	acetolactate synthase activity
IC756_RS22680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC756_RS22690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC756_RS22695	COG0583	DNA-binding transcription factor activity
IC756_RS22705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC756_RS22710	COG0210	DNA helicase
IC756_RS22725	COG3118	belongs to the thioredoxin family
IC756_RS22735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IC756_RS22740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IC756_RS22745	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IC756_RS22750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC756_RS22755	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC756_RS22760	COG1088	dTDP-glucose 4,6-dehydratase activity
IC756_RS22765	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC756_RS22770	COG0456	acetyltransferase
IC756_RS22775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IC756_RS22780	COG2244	polysaccharide biosynthetic process
IC756_RS22800	COG1113	amino acid transport
IC756_RS22825	COG0641	radical SAM
IC756_RS22835	COG3119	arylsulfatase activity
IC756_RS22840	COG3071	HemY protein
IC756_RS22845	COG2959	enzyme of heme biosynthesis
IC756_RS22850	COG1587	Uroporphyrinogen-III synthase
IC756_RS22860	COG3072	Adenylate cyclase
IC756_RS22875	COG5567	small periplasmic lipoprotein
IC756_RS22885	COG3159	Protein conserved in bacteria
IC756_RS22895	COG1011	Hydrolase
IC756_RS22900	COG0210	DNA helicase
IC756_RS22910	COG3698	Phosphodiester glycosidase
IC756_RS22915	COG0598	Magnesium transport protein CorA
IC756_RS22930	COG2962	Rard protein
IC756_RS22935	COG2050	protein possibly involved in aromatic compounds catabolism
IC756_RS22940	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IC756_RS22945	COG0514	ATP-dependent DNA helicase (RecQ)
IC756_RS22950	COG1280	lysine exporter protein (LysE YggA)
IC756_RS22955	COG1280	lysine exporter protein (LysE YggA)
IC756_RS22960	COG2267	carboxylic ester hydrolase activity
IC756_RS22965	COG0561	phosphatase activity
IC756_RS22970	COG0697	spore germination
IC756_RS22975	COG0583	DNA-binding transcription factor activity
IC756_RS22985	COG0412	Dienelactone hydrolase
IC756_RS22990	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IC756_RS22995	COG1322	Protein conserved in bacteria
IC756_RS23005	COG3165	ubiquinone biosynthetic process from chorismate
IC756_RS23015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC756_RS23020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC756_RS23025	COG0805	protein transport
IC756_RS23035	COG0250	Participates in transcription elongation, termination and antitermination
IC756_RS23040	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IC756_RS23045	COG0543	2 iron, 2 sulfur cluster binding
IC756_RS23050	COG0183	Belongs to the thiolase family
IC756_RS23065	COG1739	Uncharacterized protein family UPF0029
IC756_RS23070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC756_RS23075	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IC756_RS23105	COG1763	Mo-molybdopterin cofactor biosynthetic process
IC756_RS23110	COG0746	molybdenum cofactor guanylyltransferase activity
IC756_RS23115	COG3084	Protein conserved in bacteria
IC756_RS23120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC756_RS23125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC756_RS23130	COG5339	Protein conserved in bacteria
IC756_RS23135	COG0204	Acyl-transferase
IC756_RS23140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IC756_RS23140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IC756_RS23155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC756_RS23165	COG2204	response regulator
IC756_RS23170	COG3852	Histidine kinase
IC756_RS23175	COG0174	glutamine synthetase
IC756_RS23180	COG1217	gtp-binding protein TYPA
IC756_RS23185	COG2188	Transcriptional regulator
IC756_RS23205	COG2271	Major facilitator Superfamily
IC756_RS23210	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IC756_RS23215	COG2211	Major facilitator Superfamily
IC756_RS23220	COG2211	Major facilitator Superfamily
IC756_RS23225	COG1501	Belongs to the glycosyl hydrolase 31 family
IC756_RS23230	COG2017	converts alpha-aldose to the beta-anomer
IC756_RS23235	COG2942	2-epimerase
IC756_RS23240	COG3684	Belongs to the aldolase LacD family
IC756_RS23245	COG2084	Dehydrogenase
IC756_RS23250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC756_RS23255	COG1349	DNA-binding transcription factor activity
IC756_RS23260	COG1011	Hydrolase
IC756_RS23275	COG0456	acetyltransferase
IC756_RS23285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC756_RS23290	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC756_RS23300	COG2864	formate dehydrogenase
IC756_RS23305	COG0437	4 iron, 4 sulfur cluster binding
IC756_RS23355	COG1917	Cupin 2, conserved barrel domain protein
IC756_RS23355	COG4977	sequence-specific DNA binding
IC756_RS23365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC756_RS23375	COG2258	MOSC domain
IC756_RS23380	COG2205	protein histidine kinase activity
IC756_RS23385	COG0745	RESPONSE REGULATOR receiver
IC756_RS23390	COG3678	ATP-independent chaperone mediated protein folding
IC756_RS23405	COG4974	Belongs to the 'phage' integrase family
IC756_RS23455	COG2207	Transcriptional regulator
IC756_RS23455	COG3708	Transcriptional regulator
IC756_RS23505	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IC756_RS23535	COG3436	PFAM IS66 Orf2 family protein
IC756_RS23755	COG2826	transposase and inactivated derivatives, IS30 family
IC756_RS23910	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IC756_RS23925	COG3436	PFAM IS66 Orf2 family protein
IC756_RS23965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC756_RS23970	COG1459	type II secretion system
IC756_RS23975	COG2165	general secretion pathway protein
IC756_RS24005	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IC756_RS24060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IC756_RS24115	COG2819	hydrolase of the alpha beta superfamily
IC756_RS24130	COG1620	l-lactate permease
IC756_RS24135	COG2186	Transcriptional regulator
IC756_RS24150	COG2826	transposase and inactivated derivatives, IS30 family
IC756_RS24210	COG2826	transposase and inactivated derivatives, IS30 family