locus-tag	class	description
EPG46_RS00035	COG0656	L-ascorbic acid biosynthetic process
EPG46_RS00040	COG0583	DNA-binding transcription factor activity
EPG46_RS00055	COG1388	LysM domain
EPG46_RS00055	COG0741	lytic transglycosylase activity
EPG46_RS00065	COG2226	methyltransferase
EPG46_RS00075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EPG46_RS00095	COG4104	PAAR repeat-containing protein
EPG46_RS00100	COG3157	Type VI secretion system effector, Hcp
EPG46_RS00185	COG3501	Rhs element vgr protein
EPG46_RS00220	COG5433	transposase activity
EPG46_RS00225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPG46_RS00235	COG1960	acyl-CoA dehydrogenase activity
EPG46_RS00245	COG0121	glutamine amidotransferase
EPG46_RS00250	COG3034	peptidoglycan biosynthetic process
EPG46_RS00255	COG3041	Addiction module toxin RelE StbE family
EPG46_RS00260	COG3077	Addiction module antitoxin, RelB DinJ family
EPG46_RS00265	COG0791	NLP P60 protein
EPG46_RS00270	COG1943	Transposase
EPG46_RS00290	COG2161	toxin-antitoxin pair type II binding
EPG46_RS00300	COG0454	-acetyltransferase
EPG46_RS00305	COG1690	Belongs to the RtcB family
EPG46_RS00310	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPG46_RS00315	COG2195	Cleaves the N-terminal amino acid of tripeptides
EPG46_RS00335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EPG46_RS00370	COG4983	Phage plasmid primase, P4 family domain protein
EPG46_RS00375	COG4983	Phage plasmid primase, P4 family domain protein
EPG46_RS00430	COG0477	Major facilitator Superfamily
EPG46_RS00435	COG0668	transmembrane transport
EPG46_RS00530	COG3344	reverse transcriptase
EPG46_RS00605	COG3468	outer membrane autotransporter barrel domain protein
EPG46_RS00625	COG2003	Belongs to the UPF0758 family
EPG46_RS00680	COG0583	DNA-binding transcription factor activity
EPG46_RS00685	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EPG46_RS00690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EPG46_RS00695	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EPG46_RS00700	COG2080	2 iron, 2 sulfur cluster binding
EPG46_RS00705	COG3477	response to acidic pH
EPG46_RS00710	COG0727	PFAM Uncharacterised protein family (UPF0153)
EPG46_RS00715	COG3121	Chaperone
EPG46_RS00725	COG3188	usher protein
EPG46_RS00770	COG1388	LysM domain
EPG46_RS00775	COG3708	Transcriptional regulator
EPG46_RS00775	COG2207	Transcriptional regulator
EPG46_RS00785	COG3059	membrane
EPG46_RS00795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPG46_RS00800	COG2207	Transcriptional regulator
EPG46_RS00805	COG0247	lactate metabolic process
EPG46_RS00810	COG1139	Iron-sulfur cluster binding protein
EPG46_RS00815	COG1556	Lactate utilization protein
EPG46_RS00840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EPG46_RS00850	COG2200	EAL domain
EPG46_RS00850	COG2771	luxR family
EPG46_RS00855	COG0583	DNA-binding transcription factor activity
EPG46_RS00865	COG0666	response to abiotic stimulus
EPG46_RS00875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EPG46_RS00880	COG1304	FMN binding
EPG46_RS00890	COG0549	Belongs to the carbamate kinase family
EPG46_RS00895	COG0402	S-adenosylhomocysteine deaminase activity
EPG46_RS00900	COG1064	alcohol dehydrogenase
EPG46_RS00915	COG1280	lysine exporter protein (LysE YggA)
EPG46_RS00925	COG3829	transcription factor binding
EPG46_RS00930	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EPG46_RS00935	COG0372	Belongs to the citrate synthase family
EPG46_RS00940	COG2079	MmgE PrpD family protein
EPG46_RS00945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EPG46_RS00950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EPG46_RS00955	COG0402	S-adenosylhomocysteine deaminase activity
EPG46_RS00960	COG0583	DNA-binding transcription factor activity
EPG46_RS00965	COG0288	reversible hydration of carbon dioxide
EPG46_RS00975	COG2807	transmembrane transport
EPG46_RS00980	COG0110	maltose O-acetyltransferase activity
EPG46_RS00985	COG2223	nitrite transmembrane transporter activity
EPG46_RS00990	COG3250	beta-galactosidase activity
EPG46_RS00995	COG1609	Transcriptional regulator
EPG46_RS01000	COG1414	Transcriptional regulator
EPG46_RS01020	COG3971	2-oxopent-4-enoate hydratase activity
EPG46_RS01035	COG2814	Major facilitator Superfamily
EPG46_RS01040	COG3122	Protein conserved in bacteria
EPG46_RS01070	COG1215	transferase activity, transferring glycosyl groups
EPG46_RS01075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EPG46_RS01080	COG4521	taurine ABC transporter
EPG46_RS01090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EPG46_RS01095	COG2175	clavaminate synthase activity
EPG46_RS01100	COG0113	porphobilinogen synthase activity
EPG46_RS01105	COG3468	outer membrane autotransporter barrel domain protein
EPG46_RS01110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EPG46_RS01115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EPG46_RS01120	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EPG46_RS01140	COG1181	Belongs to the D-alanine--D-alanine ligase family
EPG46_RS01155	COG1785	Belongs to the alkaline phosphatase family
EPG46_RS01165	COG3706	GGDEF domain
EPG46_RS01170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPG46_RS01190	COG4126	flavin adenine dinucleotide binding
EPG46_RS01215	COG1940	carbohydrate kinase activity
EPG46_RS01220	COG2814	Major facilitator Superfamily
EPG46_RS01225	COG0419	ATPase involved in DNA repair
EPG46_RS01230	COG0420	3'-5' exonuclease activity
EPG46_RS01235	COG0745	RESPONSE REGULATOR receiver
EPG46_RS01240	COG5002	protein histidine kinase activity
EPG46_RS01245	COG1114	Component of the transport system for branched-chain amino acids
EPG46_RS01250	COG1113	amino acid transport
EPG46_RS01255	COG0366	Alpha amylase catalytic
EPG46_RS01275	COG1862	Preprotein translocase
EPG46_RS01280	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EPG46_RS01285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EPG46_RS01290	COG1403	HNH endonuclease
EPG46_RS01295	COG3248	Nucleoside-binding outer membrane protein
EPG46_RS01300	COG4238	major outer membrane lipoprotein
EPG46_RS01310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPG46_RS01310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPG46_RS01325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EPG46_RS01330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EPG46_RS01335	COG0667	Aldo Keto reductase
EPG46_RS01345	COG0142	geranyltranstransferase activity
EPG46_RS01360	COG0693	protein deglycase activity
EPG46_RS01365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPG46_RS01375	COG2814	Major facilitator Superfamily
EPG46_RS01385	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EPG46_RS01390	COG1845	cytochrome c oxidase, subunit III
EPG46_RS01395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EPG46_RS01400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EPG46_RS01405	COG2223	nitrite transmembrane transporter activity
EPG46_RS01410	COG3056	Lipoprotein
EPG46_RS01415	COG0271	Belongs to the BolA IbaG family
EPG46_RS01435	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EPG46_RS01440	COG0776	regulation of translation
EPG46_RS01445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EPG46_RS01450	COG1555	photosystem II stabilization
EPG46_RS01455	COG0824	Thioesterase
EPG46_RS01465	COG4533	DNA binding
EPG46_RS01475	COG1522	sequence-specific DNA binding
EPG46_RS01480	COG1132	(ABC) transporter
EPG46_RS01485	COG1132	(ABC) transporter
EPG46_RS01490	COG0347	Belongs to the P(II) protein family
EPG46_RS01495	COG0004	ammonium transporteR
EPG46_RS01500	COG1946	Acyl-CoA thioesterase
EPG46_RS01505	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EPG46_RS01510	COG3695	enzyme binding
EPG46_RS01520	COG5507	3-demethylubiquinone-9 3-methyltransferase
EPG46_RS01525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EPG46_RS01535	COG0110	maltose O-acetyltransferase activity
EPG46_RS01550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPG46_RS01555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPG46_RS01565	COG1196	nuclear chromosome segregation
EPG46_RS01565	COG3264	Mechanosensitive ion channel
EPG46_RS01575	COG3923	Primosomal replication protein n
EPG46_RS01580	COG2832	Protein of unknown function (DUF454)
EPG46_RS01590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPG46_RS01625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS01630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EPG46_RS01630	COG4651	solute:proton antiporter activity
EPG46_RS01635	COG2223	nitrite transmembrane transporter activity
EPG46_RS01640	COG0737	Belongs to the 5'-nucleotidase family
EPG46_RS01645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPG46_RS01650	COG3735	TraB family
EPG46_RS01655	COG3093	addiction module antidote protein HigA
EPG46_RS01660	COG2217	Heavy metal translocating P-type atpase
EPG46_RS01665	COG2066	Belongs to the glutaminase family
EPG46_RS01670	COG0531	amino acid
EPG46_RS01675	COG0789	Transcriptional regulator
EPG46_RS01680	COG1585	Membrane protein implicated in regulation of membrane protease activity
EPG46_RS01685	COG0330	HflC and HflK could
EPG46_RS01690	COG4619	ABC transporter
EPG46_RS01695	COG0390	transport system, permease component
EPG46_RS01700	COG3118	belongs to the thioredoxin family
EPG46_RS01705	COG0300	oxidoreductase activity
EPG46_RS01710	COG2755	lipolytic protein G-D-S-L family
EPG46_RS01715	COG4181	ATPase activity
EPG46_RS01720	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EPG46_RS01730	COG3436	PFAM IS66 Orf2 family protein
EPG46_RS01750	COG3209	COG3209 Rhs family protein
EPG46_RS01775	COG0583	DNA-binding transcription factor activity
EPG46_RS01785	COG1414	Transcriptional regulator
EPG46_RS01790	COG3960	tartronate-semialdehyde synthase activity
EPG46_RS01795	COG3622	Belongs to the hyi family
EPG46_RS01800	COG2084	Dehydrogenase
EPG46_RS01805	COG1953	Uracil, thiamine, allantoin
EPG46_RS01815	COG2233	PERMEase
EPG46_RS01820	COG1929	Belongs to the glycerate kinase type-1 family
EPG46_RS01835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EPG46_RS01840	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EPG46_RS01845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EPG46_RS01850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EPG46_RS01860	COG0549	Belongs to the carbamate kinase family
EPG46_RS01865	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPG46_RS01870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPG46_RS01880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPG46_RS01890	COG1988	membrane-bound metal-dependent
EPG46_RS01895	COG2501	S4 domain
EPG46_RS01905	COG3539	Fimbrial protein
EPG46_RS01910	COG3121	Chaperone
EPG46_RS01915	COG3188	usher protein
EPG46_RS01920	COG3539	Fimbrial protein
EPG46_RS01925	COG3539	Fimbrial protein
EPG46_RS01930	COG2197	response regulator
EPG46_RS01940	COG2207	Transcriptional regulator
EPG46_RS01950	COG4783	chaperone-mediated protein folding
EPG46_RS01955	COG1215	transferase activity, transferring glycosyl groups
EPG46_RS01960	COG5002	protein histidine kinase activity
EPG46_RS01965	COG0745	RESPONSE REGULATOR receiver
EPG46_RS01970	COG1538	Outer membrane efflux protein
EPG46_RS01975	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPG46_RS01980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPG46_RS01985	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPG46_RS01990	COG1113	amino acid transport
EPG46_RS01995	COG0668	transmembrane transport
EPG46_RS02000	COG0778	Nitroreductase
EPG46_RS02040	COG0438	transferase activity, transferring glycosyl groups
EPG46_RS02045	COG0438	transferase activity, transferring glycosyl groups
EPG46_RS02050	COG0500	methyltransferase
EPG46_RS02070	COG3423	Transcriptional regulator
EPG46_RS02105	COG2977	Belongs to the P-Pant transferase superfamily
EPG46_RS02110	COG4771	TonB-dependent receptor
EPG46_RS02120	COG2382	esterase
EPG46_RS02125	COG3251	PFAM MbtH domain protein
EPG46_RS02130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EPG46_RS02130	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EPG46_RS02135	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EPG46_RS02140	COG1120	ATPase activity
EPG46_RS02145	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPG46_RS02150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPG46_RS02160	COG4592	Periplasmic binding protein
EPG46_RS02165	COG1169	isochorismate synthase
EPG46_RS02170	COG1021	2,3-dihydroxybenzoate-AMP ligase
EPG46_RS02175	COG3433	isochorismatase activity
EPG46_RS02175	COG1535	isochorismatase
EPG46_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS02185	COG2050	protein possibly involved in aromatic compounds catabolism
EPG46_RS02190	COG1966	Carbon starvation protein
EPG46_RS02195	COG2879	small protein
EPG46_RS02200	COG0371	Dehydrogenase
EPG46_RS02205	COG0436	Aminotransferase
EPG46_RS02210	COG1475	DNA binding
EPG46_RS02215	COG3969	phosphoadenosine phosphosulfate
EPG46_RS02220	COG0583	DNA-binding transcription factor activity
EPG46_RS02225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EPG46_RS02230	COG0450	alkyl hydroperoxide reductase
EPG46_RS02235	COG3634	alkyl hydroperoxide reductase activity
EPG46_RS02240	COG0589	response to stress
EPG46_RS02245	COG1063	alcohol dehydrogenase
EPG46_RS02250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EPG46_RS02255	COG3719	Belongs to the RNase T2 family
EPG46_RS02260	COG0471	metal ion transport
EPG46_RS02275	COG3051	citrate lyase alpha subunit
EPG46_RS02280	COG2301	Belongs to the HpcH HpaI aldolase family
EPG46_RS02290	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EPG46_RS02295	COG3290	protein histidine kinase activity
EPG46_RS02300	COG4565	transcriptional regulatory protein
EPG46_RS02305	COG3069	C4-dicarboxylate transmembrane transporter activity
EPG46_RS02330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPG46_RS02340	COG0583	DNA-binding transcription factor activity
EPG46_RS02355	COG1686	Belongs to the peptidase S11 family
EPG46_RS02360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EPG46_RS02365	COG0772	Belongs to the SEDS family
EPG46_RS02370	COG0768	penicillin binding
EPG46_RS02380	COG0799	negative regulation of ribosome biogenesis
EPG46_RS02385	COG0406	alpha-ribazole phosphatase activity
EPG46_RS02395	COG1466	dna polymerase III delta subunit
EPG46_RS02410	COG2888	peptidyl-tyrosine sulfation
EPG46_RS02415	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EPG46_RS02425	COG2214	Heat shock protein DnaJ domain protein
EPG46_RS02430	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EPG46_RS02440	COG2214	Heat shock protein DnaJ domain protein
EPG46_RS02445	COG0443	Heat shock 70 kDa protein
EPG46_RS02455	COG1126	abc transporter atp-binding protein
EPG46_RS02460	COG0765	amino acid transport
EPG46_RS02465	COG0765	amino acid transport
EPG46_RS02470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPG46_RS02475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EPG46_RS02480	COG4535	Mg2 and Co2 transporter CorC
EPG46_RS02490	COG1702	phosphate starvation-inducible protein PhoH
EPG46_RS02500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EPG46_RS02540	COG0367	asparagine synthase
EPG46_RS02545	COG0647	UMP catabolic process
EPG46_RS02550	COG1846	Transcriptional regulator
EPG46_RS02550	COG1940	carbohydrate kinase activity
EPG46_RS02555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EPG46_RS02565	COG1263	PTS System
EPG46_RS02565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS02565	COG2190	(PTS) system
EPG46_RS02585	COG0735	belongs to the Fur family
EPG46_RS02595	COG0716	FMN binding
EPG46_RS02605	COG0596	Alpha beta hydrolase
EPG46_RS02610	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EPG46_RS02615	COG0033	Phosphoglucomutase
EPG46_RS02635	COG0531	amino acid
EPG46_RS02650	COG0745	RESPONSE REGULATOR receiver
EPG46_RS02655	COG2205	protein histidine kinase activity
EPG46_RS02685	COG3209	COG3209 Rhs family protein
EPG46_RS02695	COG3209	COG3209 Rhs family protein
EPG46_RS02705	COG3209	COG3209 Rhs family protein
EPG46_RS02730	COG3272	Protein of unknown function (DUF1722)
EPG46_RS02735	COG0415	Belongs to the DNA photolyase family
EPG46_RS02740	COG3104	oligopeptide transport
EPG46_RS02745	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EPG46_RS02750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EPG46_RS02755	COG1984	allophanate hydrolase subunit 2
EPG46_RS02770	COG3180	Ammonia monooxygenase
EPG46_RS02775	COG3539	Fimbrial protein
EPG46_RS02780	COG3121	Chaperone
EPG46_RS02785	COG3188	usher protein
EPG46_RS02790	COG3539	Fimbrial protein
EPG46_RS02795	COG0372	Belongs to the citrate synthase family
EPG46_RS02805	COG2009	succinate dehydrogenase
EPG46_RS02810	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EPG46_RS02815	COG1053	succinate dehydrogenase
EPG46_RS02820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EPG46_RS02825	COG0567	Dehydrogenase, E1 component
EPG46_RS02830	COG0508	dehydrogenase complex catalyzes the overall conversion of
EPG46_RS02840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EPG46_RS02845	COG2188	Transcriptional regulator
EPG46_RS02850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS02850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS02850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS02855	COG0383	alpha-mannosidase activity
EPG46_RS02860	COG1271	oxidase subunit
EPG46_RS02865	COG1294	oxidase, subunit
EPG46_RS02870	COG4890	Cyd operon protein YbgT
EPG46_RS02875	COG3790	cyd operon protein YbgE
EPG46_RS02880	COG0824	Thioesterase
EPG46_RS02885	COG0811	peptide transport
EPG46_RS02890	COG0848	biopolymer transport protein
EPG46_RS02895	COG3064	Membrane
EPG46_RS02905	COG2885	chlorophyll binding
EPG46_RS02910	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EPG46_RS02960	COG3201	nicotinamide mononucleotide transporter
EPG46_RS02965	COG1230	cation diffusion facilitator family transporter
EPG46_RS02975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPG46_RS02985	COG2017	converts alpha-aldose to the beta-anomer
EPG46_RS02995	COG1085	galactose-1-phosphate uridylyltransferase
EPG46_RS03000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPG46_RS03005	COG1119	ATPase activity
EPG46_RS03010	COG2005	Transcriptional regulator
EPG46_RS03010	COG3585	molybdate ion transport
EPG46_RS03020	COG0725	ABC transporter, periplasmic molybdate-binding protein
EPG46_RS03025	COG4149	molybdate abc transporter
EPG46_RS03030	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EPG46_RS03035	COG0561	phosphatase activity
EPG46_RS03045	COG0583	DNA-binding transcription factor activity
EPG46_RS03050	COG2828	Protein conserved in bacteria
EPG46_RS03055	COG0471	metal ion transport
EPG46_RS03060	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EPG46_RS03065	COG4677	pectinesterase activity
EPG46_RS03070	COG1881	PFAM PEBP family protein
EPG46_RS03075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EPG46_RS03090	COG2226	methyltransferase
EPG46_RS03095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EPG46_RS03105	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EPG46_RS03115	COG0521	Mo-molybdopterin cofactor biosynthetic process
EPG46_RS03125	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EPG46_RS03130	COG0314	molybdopterin synthase activity
EPG46_RS03135	COG0670	Belongs to the BI1 family
EPG46_RS03140	COG0670	Belongs to the BI1 family
EPG46_RS03145	COG0392	lysyltransferase activity
EPG46_RS03150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPG46_RS03155	COG3568	Endonuclease Exonuclease Phosphatase
EPG46_RS03165	COG0842	Transport permease protein
EPG46_RS03170	COG0842	Transport permease protein
EPG46_RS03175	COG1131	(ABC) transporter
EPG46_RS03185	COG1309	transcriptional regulator
EPG46_RS03190	COG0513	Belongs to the DEAD box helicase family
EPG46_RS03195	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EPG46_RS03200	COG1199	ATP-dependent helicase activity
EPG46_RS03205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPG46_RS03210	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EPG46_RS03220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EPG46_RS03230	COG4774	siderophore transport
EPG46_RS03245	COG0668	transmembrane transport
EPG46_RS03250	COG1126	abc transporter atp-binding protein
EPG46_RS03255	COG0765	amino acid transport
EPG46_RS03260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPG46_RS03270	COG5006	permease, DMT superfamily
EPG46_RS03280	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EPG46_RS03285	COG2194	sulfuric ester hydrolase activity
EPG46_RS03295	COG1321	iron dependent repressor
EPG46_RS03300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EPG46_RS03305	COG1376	ErfK ybiS ycfS ynhG family protein
EPG46_RS03310	COG0488	(ABC) transporter
EPG46_RS03320	COG0561	phosphatase activity
EPG46_RS03325	COG1882	Formate acetyltransferase
EPG46_RS03330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPG46_RS03335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPG46_RS03340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EPG46_RS03345	COG0303	'Molybdopterin
EPG46_RS03350	COG1446	asparaginase
EPG46_RS03355	COG4172	Belongs to the ABC transporter superfamily
EPG46_RS03360	COG0747	negative chemotaxis
EPG46_RS03370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPG46_RS03385	COG2200	EAL domain
EPG46_RS03390	COG2199	diguanylate cyclase activity
EPG46_RS03405	COG2133	pyrroloquinoline quinone binding
EPG46_RS03410	COG0625	glutathione transferase activity
EPG46_RS03415	COG1686	Belongs to the peptidase S11 family
EPG46_RS03420	COG1349	DNA-binding transcription factor activity
EPG46_RS03425	COG0671	phosphoesterase, PA-phosphatase related
EPG46_RS03430	COG2814	Major facilitator Superfamily
EPG46_RS03440	COG0561	phosphatase activity
EPG46_RS03445	COG0738	Major facilitator superfamily
EPG46_RS03450	COG3226	Transcriptional regulator
EPG46_RS03465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EPG46_RS03490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EPG46_RS03495	COG3842	ATPase activity
EPG46_RS03500	COG1176	ABC-type spermidine putrescine transport system, permease component I
EPG46_RS03505	COG1177	transmembrane transport
EPG46_RS03520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPG46_RS03525	COG4160	amino acid transport
EPG46_RS03530	COG4215	(ABC) transporter
EPG46_RS03535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPG46_RS03540	COG1126	abc transporter atp-binding protein
EPG46_RS03555	COG3023	N-Acetylmuramoyl-L-alanine amidase
EPG46_RS03560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EPG46_RS03565	COG0702	epimerase
EPG46_RS03570	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EPG46_RS03575	COG0028	Belongs to the TPP enzyme family
EPG46_RS03580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPG46_RS03590	COG2431	L-lysine efflux transmembrane transporter activity
EPG46_RS03600	COG3593	DNA synthesis involved in DNA repair
EPG46_RS03605	COG2990	Protein conserved in bacteria
EPG46_RS03610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPG46_RS03615	COG1136	(ABC) transporter
EPG46_RS03615	COG0577	efflux transmembrane transporter activity
EPG46_RS03620	COG1278	Cold shock
EPG46_RS03630	COG3311	Transcriptional regulator
EPG46_RS03670	COG0740	serine-type endopeptidase activity
EPG46_RS03690	COG0542	response to heat
EPG46_RS03710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EPG46_RS03715	COG4988	ABC transporter
EPG46_RS03720	COG0492	ferredoxin-NADP+ reductase activity
EPG46_RS03725	COG1522	sequence-specific DNA binding
EPG46_RS03730	COG1674	ftsk spoiiie
EPG46_RS03730	COG1178	ABC-type Fe3 transport system permease component
EPG46_RS03740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EPG46_RS03750	COG0243	molybdopterin cofactor binding
EPG46_RS03755	COG0437	4 iron, 4 sulfur cluster binding
EPG46_RS03760	COG3302	dmso reductase anchor subunit
EPG46_RS03765	COG1335	isochorismatase
EPG46_RS03775	COG0531	amino acid
EPG46_RS03780	COG0583	DNA-binding transcription factor activity
EPG46_RS03785	COG2249	NAD(P)H dehydrogenase (quinone) activity
EPG46_RS03790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPG46_RS03795	COG1882	Formate acetyltransferase
EPG46_RS03800	COG2116	formate transmembrane transporter activity
EPG46_RS03805	COG1944	ATP diphosphatase activity
EPG46_RS03810	COG2323	membrane
EPG46_RS03825	COG0501	Belongs to the peptidase M48B family
EPG46_RS03835	COG0539	negative regulation of cytoplasmic translation
EPG46_RS03845	COG2333	competence protein COMEC
EPG46_RS03845	COG0658	competence protein
EPG46_RS03850	COG1132	(ABC) transporter
EPG46_RS03855	COG1663	tetraacyldisaccharide 4'-kinase activity
EPG46_RS03860	COG3214	Protein conserved in bacteria
EPG46_RS03875	COG3173	Aminoglycoside phosphotransferase
EPG46_RS03880	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EPG46_RS03885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EPG46_RS03895	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EPG46_RS03905	COG2989	Protein conserved in bacteria
EPG46_RS03910	COG3108	Peptidase M15
EPG46_RS03915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EPG46_RS03920	COG1448	Aminotransferase
EPG46_RS03925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EPG46_RS03940	COG0308	aminopeptidase N
EPG46_RS03945	COG1116	anion transmembrane transporter activity
EPG46_RS03950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EPG46_RS03960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EPG46_RS03965	COG0431	NADPH-dependent FMN reductase
EPG46_RS03970	COG3539	Fimbrial protein
EPG46_RS03975	COG3121	Chaperone
EPG46_RS03980	COG3188	usher protein
EPG46_RS03985	COG3539	Fimbrial protein
EPG46_RS03990	COG3539	Fimbrial protein
EPG46_RS03995	COG3539	Fimbrial protein
EPG46_RS04000	COG3121	Chaperone
EPG46_RS04015	COG0633	Ferredoxin
EPG46_RS04015	COG3217	Mosc domain protein beta barrel domain protein
EPG46_RS04025	COG0488	(ABC) transporter
EPG46_RS04030	COG2995	paraquat-inducible protein a
EPG46_RS04035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EPG46_RS04035	COG3008	intermembrane lipid transfer
EPG46_RS04040	COG3009	Protein conserved in bacteria
EPG46_RS04045	COG3130	regulation of translation
EPG46_RS04055	COG1067	ATP-dependent peptidase activity
EPG46_RS04065	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EPG46_RS04065	COG2885	chlorophyll binding
EPG46_RS04075	COG3070	regulator of competence-specific genes
EPG46_RS04080	COG1289	transmembrane transporter activity
EPG46_RS04085	COG3304	Inner membrane component domain
EPG46_RS04090	COG0210	DNA helicase
EPG46_RS04105	COG1832	CoA-binding protein
EPG46_RS04120	COG1254	Belongs to the acylphosphatase family
EPG46_RS04125	COG2920	part of a sulfur-relay system
EPG46_RS04130	COG0670	Belongs to the BI1 family
EPG46_RS04140	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EPG46_RS04145	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EPG46_RS04150	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
EPG46_RS04155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EPG46_RS04160	COG1999	signal sequence binding
EPG46_RS04165	COG1773	rubredoxin
EPG46_RS04170	COG1271	oxidase subunit
EPG46_RS04175	COG1294	oxidase, subunit
EPG46_RS04190	COG0489	protein tyrosine kinase activity
EPG46_RS04190	COG3206	protein involved in exopolysaccharide biosynthesis
EPG46_RS04195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPG46_RS04200	COG1596	polysaccharide export
EPG46_RS04205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPG46_RS04225	COG1278	Cold shock
EPG46_RS04230	COG1278	Cold shock
EPG46_RS04250	COG0348	domain, Protein
EPG46_RS04255	COG2198	Histidine kinase
EPG46_RS04255	COG2205	protein histidine kinase activity
EPG46_RS04255	COG0784	Response regulator, receiver
EPG46_RS04260	COG1879	ABC-type sugar transport system periplasmic component
EPG46_RS04265	COG0745	RESPONSE REGULATOR receiver
EPG46_RS04270	COG3005	denitrification pathway
EPG46_RS04275	COG0243	molybdopterin cofactor binding
EPG46_RS04280	COG3381	protein complex oligomerization
EPG46_RS04315	COG3729	General stress protein
EPG46_RS04320	COG2233	PERMEase
EPG46_RS04355	COG1309	transcriptional regulator
EPG46_RS04360	COG0506	proline dehydrogenase activity
EPG46_RS04360	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EPG46_RS04360	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EPG46_RS04370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPG46_RS04380	COG2822	iron ion transport
EPG46_RS04385	COG2837	iron assimilation
EPG46_RS04390	COG1702	phosphate starvation-inducible protein PhoH
EPG46_RS04395	COG3658	cytochrome
EPG46_RS04400	COG1215	transferase activity, transferring glycosyl groups
EPG46_RS04405	COG0726	polysaccharide deacetylase
EPG46_RS04405	COG1649	PFAM Uncharacterised BCR, COG1649
EPG46_RS04410	COG0457	Tetratricopeptide repeat
EPG46_RS04415	COG3706	GGDEF domain
EPG46_RS04455	COG3381	protein complex oligomerization
EPG46_RS04465	COG1462	curli production assembly transport component CsgG
EPG46_RS04480	COG2197	response regulator
EPG46_RS04505	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EPG46_RS04510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPG46_RS04525	COG2943	transferase activity, transferring hexosyl groups
EPG46_RS04530	COG5645	(Lipo)protein
EPG46_RS04545	COG1560	Kdo2-lipid A biosynthetic process
EPG46_RS04555	COG2353	YceI-like domain
EPG46_RS04560	COG3038	cytochrome b561
EPG46_RS04595	COG2999	glutathione oxidoreductase activity
EPG46_RS04605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPG46_RS04615	COG0673	inositol 2-dehydrogenase activity
EPG46_RS04620	COG0728	peptidoglycan biosynthetic process
EPG46_RS04625	COG3418	PFAM FlgN family protein
EPG46_RS04630	COG2747	anti-sigma28 factor FlgM
EPG46_RS04635	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EPG46_RS04640	COG1815	bacterial-type flagellum-dependent cell motility
EPG46_RS04645	COG1558	bacterial-type flagellum-dependent cell motility
EPG46_RS04650	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EPG46_RS04655	COG1749	Flagellar hook protein flgE
EPG46_RS04660	COG4787	bacterial-type flagellum-dependent cell motility
EPG46_RS04665	COG4786	Flagellar basal body rod
EPG46_RS04680	COG1705	Flagellar rod assembly protein muramidase FlgJ
EPG46_RS04680	COG3951	Flagellar rod assembly protein muramidase FlgJ
EPG46_RS04685	COG1256	bacterial-type flagellum assembly
EPG46_RS04690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPG46_RS04695	COG1530	ribonuclease E activity
EPG46_RS04700	COG0564	pseudouridine synthase activity
EPG46_RS04705	COG0424	maF-like protein
EPG46_RS04710	COG1399	metal-binding, possibly nucleic acid-binding protein
EPG46_RS04730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EPG46_RS04735	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS04745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EPG46_RS04750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EPG46_RS04755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPG46_RS04765	COG0470	DNA polymerase III
EPG46_RS04770	COG0084	hydrolase, TatD family'
EPG46_RS04775	COG1263	PTS System
EPG46_RS04775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS04780	COG4773	Receptor
EPG46_RS04785	COG0537	adenosine 5'-monophosphoramidase activity
EPG46_RS04790	COG5633	Lipoprotein
EPG46_RS04795	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
EPG46_RS04815	COG1252	NADH dehydrogenase
EPG46_RS04820	COG3134	Outer membrane lipoprotein
EPG46_RS04825	COG1309	transcriptional regulator
EPG46_RS04835	COG1388	LysM domain
EPG46_RS04835	COG1376	ErfK ybiS ycfS ynhG family protein
EPG46_RS04840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPG46_RS04845	COG4763	Acyl-transferase
EPG46_RS04850	COG4591	ABC-type transport system involved in lipoprotein release permease component
EPG46_RS04855	COG1136	(ABC) transporter
EPG46_RS04860	COG4591	ABC-type transport system involved in lipoprotein release permease component
EPG46_RS04870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EPG46_RS04875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EPG46_RS04885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EPG46_RS04890	COG1177	transmembrane transport
EPG46_RS04900	COG3842	ATPase activity
EPG46_RS04910	COG2850	peptidyl-arginine hydroxylation
EPG46_RS04915	COG2205	protein histidine kinase activity
EPG46_RS04920	COG0745	RESPONSE REGULATOR receiver
EPG46_RS04925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EPG46_RS04945	COG1187	pseudouridine synthase activity
EPG46_RS04950	COG0538	isocitrate dehydrogenase activity
EPG46_RS04975	COG5562	phage envelope protein
EPG46_RS04980	COG0789	Transcriptional regulator
EPG46_RS04985	COG2200	EAL domain
EPG46_RS05010	COG2200	EAL domain
EPG46_RS05060	COG2894	cell division
EPG46_RS05085	COG0179	Fumarylacetoacetate (FAA) hydrolase
EPG46_RS05100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPG46_RS05105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPG46_RS05110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EPG46_RS05125	COG2719	SpoVR family
EPG46_RS05135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPG46_RS05145	COG1619	proteins homologs of microcin C7 resistance protein MccF
EPG46_RS05155	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EPG46_RS05160	COG2261	transglycosylase associated protein
EPG46_RS05175	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EPG46_RS05175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPG46_RS05175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS05180	COG1461	Dihydroxyacetone kinase
EPG46_RS05185	COG2376	Dihydroxyacetone kinase
EPG46_RS05190	COG3284	Transcriptional regulator
EPG46_RS05195	COG3468	outer membrane autotransporter barrel domain protein
EPG46_RS05205	COG0012	GTP binding
EPG46_RS05220	COG0659	secondary active sulfate transmembrane transporter activity
EPG46_RS05225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPG46_RS05250	COG2890	protein-(glutamine-N5) methyltransferase activity
EPG46_RS05255	COG3094	Invasion gene expression up-regulator, SirB
EPG46_RS05260	COG2912	Transglutaminase-like superfamily
EPG46_RS05285	COG0387	Pfam Sodium calcium exchanger
EPG46_RS05290	COG4572	Cation transport regulator
EPG46_RS05295	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EPG46_RS05300	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EPG46_RS05305	COG4932	domain protein
EPG46_RS05310	COG2197	response regulator
EPG46_RS05315	COG3850	Histidine kinase
EPG46_RS05320	COG2223	nitrite transmembrane transporter activity
EPG46_RS05325	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPG46_RS05330	COG1140	nitrate reductase beta subunit
EPG46_RS05335	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EPG46_RS05340	COG2181	nitrate reductase activity
EPG46_RS05370	COG0788	formyltetrahydrofolate deformylase activity
EPG46_RS05380	COG1752	Esterase of the alpha-beta hydrolase superfamily
EPG46_RS05385	COG0745	RESPONSE REGULATOR receiver
EPG46_RS05390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EPG46_RS05400	COG1435	thymidine kinase activity
EPG46_RS05410	COG1454	alcohol dehydrogenase
EPG46_RS05410	COG1012	belongs to the aldehyde dehydrogenase family
EPG46_RS05415	COG2095	MarC family integral membrane protein
EPG46_RS05420	COG4166	transmembrane transport
EPG46_RS05425	COG0601	transmembrane transport
EPG46_RS05430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPG46_RS05435	COG0444	Belongs to the ABC transporter superfamily
EPG46_RS05440	COG4608	Belongs to the ABC transporter superfamily
EPG46_RS05460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EPG46_RS05465	COG2350	Protein conserved in bacteria
EPG46_RS05470	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EPG46_RS05475	COG1607	acyl-coa hydrolase
EPG46_RS05495	COG3047	cAMP biosynthetic process
EPG46_RS05500	COG0582	viral genome integration into host DNA
EPG46_RS05510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EPG46_RS05535	COG1396	sequence-specific DNA binding
EPG46_RS05550	COG1846	Transcriptional regulator
EPG46_RS05565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EPG46_RS05595	COG1403	HNH endonuclease
EPG46_RS05600	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EPG46_RS05605	COG0484	heat shock protein binding
EPG46_RS05660	COG3772	lysozyme
EPG46_RS05680	COG4220	transposase activity
EPG46_RS05805	COG0500	methyltransferase
EPG46_RS05825	COG3685	Protein conserved in bacteria
EPG46_RS05830	COG3685	Protein conserved in bacteria
EPG46_RS05835	COG3729	General stress protein
EPG46_RS05850	COG0135	phosphoribosylanthranilate isomerase activity
EPG46_RS05850	COG0134	indole-3-glycerol-phosphate synthase activity
EPG46_RS05855	COG0512	Glutamine amidotransferase of anthranilate synthase
EPG46_RS05855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPG46_RS05860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPG46_RS05870	COG0613	PHP domain protein
EPG46_RS05875	COG0009	L-threonylcarbamoyladenylate synthase
EPG46_RS05880	COG4907	membrane protein (DUF2207)
EPG46_RS05885	COG1187	pseudouridine synthase activity
EPG46_RS05890	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EPG46_RS05895	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS05900	COG0616	signal peptide processing
EPG46_RS05910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPG46_RS05915	COG0583	DNA-binding transcription factor activity
EPG46_RS05940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EPG46_RS05950	COG0671	phosphoesterase, PA-phosphatase related
EPG46_RS05955	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EPG46_RS05960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EPG46_RS05970	COG0023	Translation Initiation Factor
EPG46_RS05980	COG1349	DNA-binding transcription factor activity
EPG46_RS05990	COG5001	Diguanylate cyclase
EPG46_RS06005	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPG46_RS06005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPG46_RS06010	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EPG46_RS06015	COG2852	Protein conserved in bacteria
EPG46_RS06020	COG4172	Belongs to the ABC transporter superfamily
EPG46_RS06025	COG4172	Belongs to the ABC transporter superfamily
EPG46_RS06030	COG4171	peptide transport system, permease
EPG46_RS06035	COG4168	peptide transport system, permease
EPG46_RS06040	COG4166	transmembrane transport
EPG46_RS06050	COG0531	amino acid
EPG46_RS06060	COG0174	glutamine synthetase
EPG46_RS06065	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EPG46_RS06070	COG1396	sequence-specific DNA binding
EPG46_RS06070	COG1917	Cupin 2, conserved barrel domain protein
EPG46_RS06075	COG1012	belongs to the aldehyde dehydrogenase family
EPG46_RS06080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EPG46_RS06085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPG46_RS06090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EPG46_RS06095	COG1842	Phage shock protein A
EPG46_RS06105	COG1983	PspC domain protein
EPG46_RS06115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPG46_RS06120	COG0366	Alpha amylase catalytic
EPG46_RS06125	COG1653	transport
EPG46_RS06130	COG1175	transmembrane transport
EPG46_RS06135	COG0395	ABC-type sugar transport system, permease component
EPG46_RS06140	COG1063	alcohol dehydrogenase
EPG46_RS06145	COG1082	Xylose isomerase domain protein TIM barrel
EPG46_RS06150	COG0673	inositol 2-dehydrogenase activity
EPG46_RS06155	COG1554	hydrolase, family 65, central catalytic
EPG46_RS06160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPG46_RS06165	COG3842	ATPase activity
EPG46_RS06175	COG1609	Transcriptional regulator
EPG46_RS06180	COG3106	COG3106 Predicted ATPase
EPG46_RS06190	COG3283	Transcriptional regulator of aromatic amino acids metabolism
EPG46_RS06195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EPG46_RS06200	COG4948	Mandelate Racemase Muconate Lactonizing
EPG46_RS06205	COG2866	Carboxypeptidase
EPG46_RS06220	COG1073	alpha beta
EPG46_RS06225	COG0583	DNA-binding transcription factor activity
EPG46_RS06230	COG4166	transmembrane transport
EPG46_RS06235	COG0668	transmembrane transport
EPG46_RS06240	COG3182	Iron-regulated membrane protein
EPG46_RS06245	COG0589	response to stress
EPG46_RS06250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EPG46_RS06255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPG46_RS06260	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EPG46_RS06265	COG1473	amidohydrolase
EPG46_RS06270	COG1473	amidohydrolase
EPG46_RS06275	COG0583	DNA-binding transcription factor activity
EPG46_RS06280	COG2840	Smr protein MutS2
EPG46_RS06295	COG0513	Belongs to the DEAD box helicase family
EPG46_RS06305	COG0589	response to stress
EPG46_RS06310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EPG46_RS06315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EPG46_RS06315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EPG46_RS06315	COG0674	pyruvate-flavodoxin oxidoreductase activity
EPG46_RS06315	COG1013	pyruvate-flavodoxin oxidoreductase activity
EPG46_RS06320	COG3042	response to heat
EPG46_RS06325	COG3187	Heat shock protein
EPG46_RS06330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPG46_RS06335	COG2911	Protein conserved in bacteria
EPG46_RS06345	COG3784	Protein of unknown function (DUF1318)
EPG46_RS06350	COG2207	Transcriptional regulator
EPG46_RS06355	COG1012	belongs to the aldehyde dehydrogenase family
EPG46_RS06360	COG3733	amine oxidase
EPG46_RS06365	COG2030	dehydratase
EPG46_RS06365	COG1012	belongs to the aldehyde dehydrogenase family
EPG46_RS06370	COG3396	Phenylacetate-CoA oxygenase
EPG46_RS06375	COG3460	Phenylacetate-CoA oxygenase
EPG46_RS06380	COG3396	Phenylacetate-CoA oxygenase
EPG46_RS06385	COG2151	metal-sulfur cluster biosynthetic enzyme
EPG46_RS06390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPG46_RS06395	COG1024	Enoyl-CoA hydratase
EPG46_RS06400	COG1024	Enoyl-CoA hydratase
EPG46_RS06405	COG1250	3-hydroxyacyl-CoA dehydrogenase
EPG46_RS06410	COG2050	protein possibly involved in aromatic compounds catabolism
EPG46_RS06415	COG0183	Belongs to the thiolase family
EPG46_RS06420	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EPG46_RS06425	COG3327	negative regulation of DNA-templated transcription, initiation
EPG46_RS06430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EPG46_RS06455	COG0667	Aldo Keto reductase
EPG46_RS06470	COG4589	Belongs to the CDS family
EPG46_RS06475	COG2267	carboxylic ester hydrolase activity
EPG46_RS06480	COG2453	phosphatase
EPG46_RS06480	COG0671	phosphoesterase, PA-phosphatase related
EPG46_RS06490	COG1643	Atp-dependent helicase
EPG46_RS06495	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EPG46_RS06500	COG1012	belongs to the aldehyde dehydrogenase family
EPG46_RS06510	COG3038	cytochrome b561
EPG46_RS06525	COG0840	transmembrane signaling receptor activity
EPG46_RS06530	COG0583	DNA-binding transcription factor activity
EPG46_RS06535	COG5383	Protein conserved in bacteria
EPG46_RS06545	COG2841	Protein conserved in bacteria
EPG46_RS06550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPG46_RS06555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EPG46_RS06560	COG1275	C4-dicarboxylate transporter malic acid transport protein
EPG46_RS06565	COG0500	methyltransferase
EPG46_RS06580	COG0675	Transposase, IS605 OrfB family
EPG46_RS06585	COG3135	benzoate transporter
EPG46_RS06590	COG1396	sequence-specific DNA binding
EPG46_RS06595	COG0826	peptidase U32
EPG46_RS06605	COG1724	mRNA binding
EPG46_RS06610	COG1598	PFAM Uncharacterised protein family UPF0150
EPG46_RS06615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EPG46_RS06620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EPG46_RS06625	COG3842	ATPase activity
EPG46_RS06630	COG1176	ABC-type spermidine putrescine transport system, permease component I
EPG46_RS06635	COG1177	transmembrane transport
EPG46_RS06660	COG3238	Protein conserved in bacteria
EPG46_RS06665	COG1247	-acetyltransferase
EPG46_RS06670	COG2130	NADP-dependent
EPG46_RS06675	COG1802	Transcriptional regulator
EPG46_RS06680	COG4772	TonB-dependent receptor
EPG46_RS06685	COG3391	amine dehydrogenase activity
EPG46_RS06690	COG1113	amino acid transport
EPG46_RS06695	COG0625	glutathione transferase activity
EPG46_RS06705	COG3501	Rhs element vgr protein
EPG46_RS06735	COG5433	transposase activity
EPG46_RS06745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EPG46_RS06750	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EPG46_RS06755	COG0384	phenazine biosynthesis protein PhzF
EPG46_RS06760	COG2181	nitrate reductase activity
EPG46_RS06765	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EPG46_RS06770	COG1140	nitrate reductase beta subunit
EPG46_RS06775	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPG46_RS06780	COG2223	nitrite transmembrane transporter activity
EPG46_RS06790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EPG46_RS06795	COG0697	spore germination
EPG46_RS06805	COG0437	4 iron, 4 sulfur cluster binding
EPG46_RS06810	COG2864	formate dehydrogenase
EPG46_RS06815	COG3093	addiction module antidote protein HigA
EPG46_RS06820	COG1064	alcohol dehydrogenase
EPG46_RS06840	COG1764	response to oxidative stress
EPG46_RS06845	COG4608	Belongs to the ABC transporter superfamily
EPG46_RS06850	COG0444	Belongs to the ABC transporter superfamily
EPG46_RS06855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPG46_RS06860	COG0601	transmembrane transport
EPG46_RS06865	COG0747	negative chemotaxis
EPG46_RS06870	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EPG46_RS06875	COG2202	Pas domain
EPG46_RS06875	COG2199	diguanylate cyclase activity
EPG46_RS06875	COG2200	EAL domain
EPG46_RS06880	COG3706	GGDEF domain
EPG46_RS06895	COG0531	amino acid
EPG46_RS06905	COG0612	Peptidase, M16
EPG46_RS06910	COG4771	TonB-dependent receptor
EPG46_RS06915	COG4178	(ABC) transporter
EPG46_RS06925	COG0641	radical SAM
EPG46_RS06930	COG3119	arylsulfatase activity
EPG46_RS06935	COG2207	Transcriptional regulator
EPG46_RS06945	COG0243	molybdopterin cofactor binding
EPG46_RS06950	COG3539	Fimbrial protein
EPG46_RS06955	COG3539	Fimbrial protein
EPG46_RS06960	COG3539	Fimbrial protein
EPG46_RS06975	COG3550	peptidyl-serine autophosphorylation
EPG46_RS06980	COG1396	sequence-specific DNA binding
EPG46_RS07045	COG3781	membrane
EPG46_RS07065	COG2066	Belongs to the glutaminase family
EPG46_RS07070	COG1012	belongs to the aldehyde dehydrogenase family
EPG46_RS07075	COG0583	DNA-binding transcription factor activity
EPG46_RS07095	COG1846	Transcriptional regulator
EPG46_RS07100	COG4977	sequence-specific DNA binding
EPG46_RS07115	COG2814	Major facilitator Superfamily
EPG46_RS07125	COG3706	GGDEF domain
EPG46_RS07130	COG3111	PFAM Bacterial OB fold (BOF) protein
EPG46_RS07135	COG1546	Belongs to the CinA family
EPG46_RS07140	COG0339	signal peptide processing
EPG46_RS07145	COG4221	oxidoreductase activity
EPG46_RS07150	COG1802	Transcriptional regulator
EPG46_RS07160	COG0246	Mannitol dehydrogenase
EPG46_RS07165	COG0477	Major facilitator Superfamily
EPG46_RS07170	COG1063	alcohol dehydrogenase
EPG46_RS07175	COG4948	Mandelate Racemase Muconate Lactonizing
EPG46_RS07190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPG46_RS07205	COG0243	molybdopterin cofactor binding
EPG46_RS07210	COG0243	molybdopterin cofactor binding
EPG46_RS07215	COG0437	4 iron, 4 sulfur cluster binding
EPG46_RS07220	COG3302	dmso reductase anchor subunit
EPG46_RS07225	COG3381	protein complex oligomerization
EPG46_RS07235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EPG46_RS07240	COG1940	carbohydrate kinase activity
EPG46_RS07245	COG0583	DNA-binding transcription factor activity
EPG46_RS07250	COG2814	Major facilitator Superfamily
EPG46_RS07265	COG3591	Belongs to the peptidase S1B family
EPG46_RS07280	COG0628	permease
EPG46_RS07285	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EPG46_RS07290	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EPG46_RS07300	COG0531	amino acid
EPG46_RS07310	COG3136	membrane protein required for alginate biosynthesis
EPG46_RS07315	COG0745	RESPONSE REGULATOR receiver
EPG46_RS07320	COG2205	protein histidine kinase activity
EPG46_RS07330	COG0114	fumarate hydratase activity
EPG46_RS07335	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EPG46_RS07335	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EPG46_RS07340	COG1482	cell wall glycoprotein biosynthetic process
EPG46_RS07345	COG5339	Protein conserved in bacteria
EPG46_RS07360	COG3250	beta-galactosidase activity
EPG46_RS07365	COG1309	transcriptional regulator
EPG46_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS07375	COG1609	Transcriptional regulator
EPG46_RS07380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS07380	COG1263	PTS System
EPG46_RS07385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EPG46_RS07395	COG0673	inositol 2-dehydrogenase activity
EPG46_RS07435	COG4659	FMN binding
EPG46_RS07445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPG46_RS07450	COG3104	oligopeptide transport
EPG46_RS07455	COG0625	glutathione transferase activity
EPG46_RS07460	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EPG46_RS07475	COG3895	Periplasmic Protein
EPG46_RS07485	COG3133	Outer membrane lipoprotein
EPG46_RS07500	COG1566	PFAM secretion protein HlyD family protein
EPG46_RS07505	COG1289	transmembrane transporter activity
EPG46_RS07510	COG2032	superoxide dismutase activity
EPG46_RS07515	COG4989	oxidoreductase activity
EPG46_RS07520	COG3313	Fe-S protein
EPG46_RS07525	COG1309	transcriptional regulator
EPG46_RS07530	COG1902	pentaerythritol trinitrate reductase activity
EPG46_RS07535	COG0346	lactoylglutathione lyase activity
EPG46_RS07540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EPG46_RS07545	COG1201	RNA secondary structure unwinding
EPG46_RS07550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EPG46_RS07555	COG0791	NLP P60 protein
EPG46_RS07560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EPG46_RS07565	COG2814	Major facilitator Superfamily
EPG46_RS07580	COG0583	DNA-binding transcription factor activity
EPG46_RS07585	COG2814	Major facilitator Superfamily
EPG46_RS07590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EPG46_RS07595	COG0307	riboflavin synthase, alpha
EPG46_RS07605	COG3468	outer membrane autotransporter barrel domain protein
EPG46_RS07625	COG4529	Protein conserved in bacteria
EPG46_RS07635	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EPG46_RS07640	COG0437	4 iron, 4 sulfur cluster binding
EPG46_RS07650	COG2414	aldehyde ferredoxin oxidoreductase
EPG46_RS07655	COG0437	4 iron, 4 sulfur cluster binding
EPG46_RS07665	COG0469	pyruvate kinase activity
EPG46_RS07670	COG4238	major outer membrane lipoprotein
EPG46_RS07675	COG1376	ErfK ybiS ycfS ynhG family protein
EPG46_RS07690	COG0719	Fe-S assembly protein
EPG46_RS07695	COG0396	ATPase activity
EPG46_RS07700	COG0719	Fe-S assembly protein
EPG46_RS07705	COG0316	Belongs to the HesB IscA family
EPG46_RS07715	COG2050	protein possibly involved in aromatic compounds catabolism
EPG46_RS07720	COG0277	FAD linked oxidase domain protein
EPG46_RS07720	COG0247	lactate metabolic process
EPG46_RS07725	COG0628	permease
EPG46_RS07740	COG0738	Major facilitator superfamily
EPG46_RS07745	COG2271	Major facilitator Superfamily
EPG46_RS07760	COG4670	ketone body catabolic process
EPG46_RS07765	COG1960	acyl-CoA dehydrogenase activity
EPG46_RS07770	COG1917	Cupin 2, conserved barrel domain protein
EPG46_RS07770	COG2207	Transcriptional regulator
EPG46_RS07775	COG2086	electron transfer activity
EPG46_RS07780	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EPG46_RS07785	COG0644	oxidoreductase
EPG46_RS07790	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EPG46_RS07795	COG0318	PFAM AMP-dependent synthetase and ligase
EPG46_RS07800	COG0574	Belongs to the PEP-utilizing enzyme family
EPG46_RS07800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPG46_RS07810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPG46_RS07815	COG4256	Hemin uptake protein
EPG46_RS07825	COG2200	EAL domain
EPG46_RS07830	COG0791	NLP P60 protein
EPG46_RS07840	COG0386	Belongs to the glutathione peroxidase family
EPG46_RS07855	COG0072	phenylalanine-tRNA ligase activity
EPG46_RS07855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPG46_RS07900	COG3137	Salt-induced outer membrane protein
EPG46_RS07905	COG1105	Belongs to the carbohydrate kinase PfkB family
EPG46_RS07915	COG3001	Fructosamine kinase
EPG46_RS07925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPG46_RS07930	COG1988	membrane-bound metal-dependent
EPG46_RS07950	COG0753	catalase activity
EPG46_RS07960	COG1486	melibiose metabolic process
EPG46_RS07965	COG2169	Transcriptional regulator
EPG46_RS07965	COG1917	Cupin 2, conserved barrel domain protein
EPG46_RS07970	COG1447	Phosphotransferase system cellobiose-specific component IIA
EPG46_RS07975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPG46_RS07980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPG46_RS07985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPG46_RS07995	COG0322	excinuclease ABC activity
EPG46_RS08005	COG3678	ATP-independent chaperone mediated protein folding
EPG46_RS08035	COG0708	Exodeoxyribonuclease III
EPG46_RS08040	COG0398	Pfam SNARE associated Golgi protein
EPG46_RS08050	COG0398	Pfam SNARE associated Golgi protein
EPG46_RS08055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPG46_RS08060	COG4134	Bacterial extracellular solute-binding protein
EPG46_RS08065	COG4135	transport system, permease component
EPG46_RS08070	COG4136	ATPase activity
EPG46_RS08075	COG2897	thiosulfate sulfurtransferase activity
EPG46_RS08080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPG46_RS08085	COG0494	nUDIX hydrolase
EPG46_RS08095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EPG46_RS08105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPG46_RS08115	COG0778	Nitroreductase
EPG46_RS08120	COG0616	signal peptide processing
EPG46_RS08125	COG0252	asparaginase activity
EPG46_RS08130	COG1335	isochorismatase
EPG46_RS08135	COG2814	Major facilitator Superfamily
EPG46_RS08140	COG1349	DNA-binding transcription factor activity
EPG46_RS08145	COG0667	Aldo Keto reductase
EPG46_RS08150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS08155	COG0191	fructose-bisphosphate aldolase activity
EPG46_RS08160	COG1063	alcohol dehydrogenase
EPG46_RS08165	COG2271	Major facilitator Superfamily
EPG46_RS08170	COG1063	alcohol dehydrogenase
EPG46_RS08175	COG3139	Protein of unknown function (DUF1315)
EPG46_RS08185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EPG46_RS08190	COG0676	glucose-6-phosphate 1-epimerase activity
EPG46_RS08195	COG0656	L-ascorbic acid biosynthetic process
EPG46_RS08200	COG3713	MltA-interacting MipA family protein
EPG46_RS08205	COG2766	serine protein kinase
EPG46_RS08230	COG2199	diguanylate cyclase activity
EPG46_RS08235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPG46_RS08250	COG2207	Transcriptional regulator
EPG46_RS08255	COG2807	transmembrane transport
EPG46_RS08260	COG3189	MarR family transcriptional regulator
EPG46_RS08265	COG3042	response to heat
EPG46_RS08270	COG2199	diguanylate cyclase activity
EPG46_RS08270	COG2203	Gaf domain
EPG46_RS08285	COG2261	transglycosylase associated protein
EPG46_RS08295	COG3615	Tellurite resistance protein tehB
EPG46_RS08305	COG0583	DNA-binding transcription factor activity
EPG46_RS08310	COG0473	3-isopropylmalate dehydrogenase activity
EPG46_RS08320	COG4638	Rieske (2fe-2S)
EPG46_RS08325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPG46_RS08330	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EPG46_RS08335	COG0318	PFAM AMP-dependent synthetase and ligase
EPG46_RS08340	COG3065	identical protein binding
EPG46_RS08345	COG1214	PFAM Peptidase M22, glycoprotease
EPG46_RS08350	COG1199	ATP-dependent helicase activity
EPG46_RS08355	COG0251	oxidation-reduction process
EPG46_RS08370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPG46_RS08380	COG1760	l-serine dehydratase
EPG46_RS08385	COG2200	EAL domain
EPG46_RS08390	COG1253	flavin adenine dinucleotide binding
EPG46_RS08395	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS08395	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS08400	COG3715	PTS system
EPG46_RS08405	COG3716	PTS system mannose fructose sorbose family IID component
EPG46_RS08420	COG2226	methyltransferase
EPG46_RS08450	COG1414	Transcriptional regulator
EPG46_RS08455	COG2814	Major facilitator Superfamily
EPG46_RS08465	COG0793	Belongs to the peptidase S41A family
EPG46_RS08475	COG1956	GAF domain-containing protein
EPG46_RS08480	COG2995	paraquat-inducible protein a
EPG46_RS08485	COG3008	intermembrane lipid transfer
EPG46_RS08505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EPG46_RS08515	COG1276	copper resistance
EPG46_RS08520	COG2372	response to copper ion
EPG46_RS08530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPG46_RS08535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EPG46_RS08540	COG1770	oligopeptidase
EPG46_RS08545	COG2979	Protein of unknown function (DUF533)
EPG46_RS08555	COG3141	response to X-ray
EPG46_RS08565	COG0800	Aldolase
EPG46_RS08570	COG0129	dihydroxy-acid dehydratase activity
EPG46_RS08575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPG46_RS08580	COG1737	Transcriptional regulator
EPG46_RS08585	COG0469	pyruvate kinase activity
EPG46_RS08590	COG1560	Kdo2-lipid A biosynthetic process
EPG46_RS08595	COG0739	heme binding
EPG46_RS08600	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EPG46_RS08610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EPG46_RS08640	COG0217	transcriptional regulatory protein
EPG46_RS08645	COG0494	nUDIX hydrolase
EPG46_RS08655	COG1335	isochorismatase
EPG46_RS08660	COG1801	Protein of unknown function DUF72
EPG46_RS08665	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EPG46_RS08685	COG3005	denitrification pathway
EPG46_RS08700	COG3102	Protein conserved in bacteria
EPG46_RS08710	COG3755	Protein conserved in bacteria
EPG46_RS08720	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EPG46_RS08725	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EPG46_RS08730	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EPG46_RS08735	COG0745	RESPONSE REGULATOR receiver
EPG46_RS08745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EPG46_RS08750	COG0840	transmembrane signaling receptor activity
EPG46_RS08755	COG0840	transmembrane signaling receptor activity
EPG46_RS08760	COG0835	chemotaxis
EPG46_RS08765	COG0643	Histidine kinase
EPG46_RS08765	COG2198	Histidine kinase
EPG46_RS08770	COG1360	Flagellar Motor Protein
EPG46_RS08775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EPG46_RS08790	COG0589	response to stress
EPG46_RS08800	COG1877	trehalose-phosphatase activity
EPG46_RS08805	COG1172	Belongs to the binding-protein-dependent transport system permease family
EPG46_RS08810	COG1129	ABC transporter
EPG46_RS08815	COG1879	ABC-type sugar transport system periplasmic component
EPG46_RS08820	COG1528	Iron-storage protein
EPG46_RS08840	COG1528	Iron-storage protein
EPG46_RS08850	COG0814	amino acid
EPG46_RS08855	COG3012	SEC-C Motif Domain Protein
EPG46_RS08855	COG3318	Belongs to the UPF0149 family
EPG46_RS08880	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EPG46_RS08905	COG3344	reverse transcriptase
EPG46_RS08955	COG2197	response regulator
EPG46_RS08970	COG2197	response regulator
EPG46_RS09000	COG1191	sigma factor activity
EPG46_RS09015	COG1516	flagellar protein fliS
EPG46_RS09025	COG0366	Alpha amylase catalytic
EPG46_RS09035	COG2391	methyltransferase activity
EPG46_RS09040	COG0425	Belongs to the sulfur carrier protein TusA family
EPG46_RS09045	COG2135	peptidase activity
EPG46_RS09065	COG1766	The M ring may be actively involved in energy transduction
EPG46_RS09070	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EPG46_RS09075	COG1317	bacterial-type flagellum organization
EPG46_RS09080	COG1157	protein secretion by the type III secretion system
EPG46_RS09085	COG2882	bacterial-type flagellum organization
EPG46_RS09090	COG3144	bacterial-type flagellum assembly
EPG46_RS09095	COG1580	Controls the rotational direction of flagella during chemotaxis
EPG46_RS09100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EPG46_RS09105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EPG46_RS09110	COG3190	flagellar
EPG46_RS09115	COG1338	Plays a role in the flagellum-specific transport system
EPG46_RS09120	COG1987	bacterial-type flagellum assembly
EPG46_RS09125	COG1684	flagellar biosynthetic protein fliR
EPG46_RS09150	COG3706	GGDEF domain
EPG46_RS09155	COG5475	Uncharacterized small protein (DUF2158)
EPG46_RS09160	COG2354	Protein conserved in bacteria
EPG46_RS09165	COG0697	spore germination
EPG46_RS09170	COG3727	T/G mismatch-specific endonuclease activity
EPG46_RS09175	COG0270	DNA (cytosine-5-)-methyltransferase activity
EPG46_RS09180	COG1418	mRNA catabolic process
EPG46_RS09190	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EPG46_RS09205	COG2205	protein histidine kinase activity
EPG46_RS09210	COG0745	RESPONSE REGULATOR receiver
EPG46_RS09215	COG2351	hydroxyisourate hydrolase activity
EPG46_RS09225	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EPG46_RS09230	COG3443	Belongs to the bacterial solute-binding protein 9 family
EPG46_RS09250	COG0582	viral genome integration into host DNA
EPG46_RS09255	COG1169	isochorismate synthase
EPG46_RS09260	COG2814	Major facilitator Superfamily
EPG46_RS09265	COG1132	(ABC) transporter
EPG46_RS09280	COG3433	isochorismatase activity
EPG46_RS09280	COG2226	methyltransferase
EPG46_RS09280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EPG46_RS09305	COG4771	TonB-dependent receptor
EPG46_RS09310	COG1388	LysM domain
EPG46_RS09310	COG4932	domain protein
EPG46_RS09310	COG2373	Large extracellular alpha-helical protein
EPG46_RS09315	COG1470	cell adhesion involved in biofilm formation
EPG46_RS09315	COG1388	LysM domain
EPG46_RS09320	COG1388	LysM domain
EPG46_RS09320	COG1470	cell adhesion involved in biofilm formation
EPG46_RS09330	COG0477	Major facilitator Superfamily
EPG46_RS09335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPG46_RS09340	COG0217	transcriptional regulatory protein
EPG46_RS09350	COG0534	Mate efflux family protein
EPG46_RS09360	COG0583	DNA-binding transcription factor activity
EPG46_RS09365	COG0583	DNA-binding transcription factor activity
EPG46_RS09375	COG1376	ErfK ybiS ycfS ynhG family protein
EPG46_RS09390	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
EPG46_RS09400	COG1349	DNA-binding transcription factor activity
EPG46_RS09405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS09425	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EPG46_RS09475	COG4983	Phage plasmid primase, P4 family domain protein
EPG46_RS09485	COG3468	outer membrane autotransporter barrel domain protein
EPG46_RS09490	COG2020	methyltransferase activity
EPG46_RS09515	COG2003	Belongs to the UPF0758 family
EPG46_RS09560	COG1289	transmembrane transporter activity
EPG46_RS09575	COG1686	Belongs to the peptidase S11 family
EPG46_RS09580	COG2925	Exonuclease
EPG46_RS09585	COG0425	Belongs to the sulfur carrier protein TusA family
EPG46_RS09590	COG2391	methyltransferase activity
EPG46_RS09595	COG0531	amino acid
EPG46_RS09605	COG0583	DNA-binding transcription factor activity
EPG46_RS09610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EPG46_RS09625	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EPG46_RS09635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EPG46_RS09635	COG0131	Imidazoleglycerol-phosphate dehydratase
EPG46_RS09640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPG46_RS09655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EPG46_RS09655	COG0140	phosphoribosyl-ATP diphosphatase activity
EPG46_RS09665	COG0438	transferase activity, transferring glycosyl groups
EPG46_RS09700	COG1088	dTDP-glucose 4,6-dehydratase activity
EPG46_RS09730	COG0463	Glycosyl transferase, family 2
EPG46_RS09790	COG1253	flavin adenine dinucleotide binding
EPG46_RS09795	COG2982	Protein involved in outer membrane biogenesis
EPG46_RS09805	COG0572	uridine kinase
EPG46_RS09815	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EPG46_RS09820	COG0443	Heat shock 70 kDa protein
EPG46_RS09830	COG0631	protein serine/threonine phosphatase activity
EPG46_RS09835	COG4245	von Willebrand factor, type A
EPG46_RS09880	COG2205	protein histidine kinase activity
EPG46_RS09885	COG0745	RESPONSE REGULATOR receiver
EPG46_RS09895	COG3609	addiction module antidote protein, CC2985 family
EPG46_RS09925	COG1063	alcohol dehydrogenase
EPG46_RS09930	COG3775	system Galactitol-specific IIC component
EPG46_RS09935	COG3414	Phosphotransferase system galactitol-specific IIB component
EPG46_RS09940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS09955	COG1830	Aldolase
EPG46_RS09960	COG2211	Major facilitator Superfamily
EPG46_RS09965	COG1397	ADP-ribosylglycohydrolase
EPG46_RS09970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS09975	COG2188	Transcriptional regulator
EPG46_RS09980	COG3757	hydrolase, family 25
EPG46_RS09985	COG0351	phosphomethylpyrimidine kinase
EPG46_RS10005	COG5455	response to cobalt ion
EPG46_RS10010	COG3539	Fimbrial protein
EPG46_RS10015	COG3188	usher protein
EPG46_RS10020	COG3121	Chaperone
EPG46_RS10025	COG3539	Fimbrial protein
EPG46_RS10035	COG0489	protein tyrosine kinase activity
EPG46_RS10055	COG4808	Protein conserved in bacteria
EPG46_RS10060	COG4807	Protein conserved in bacteria
EPG46_RS10065	COG3279	Response regulator of the LytR AlgR family
EPG46_RS10070	COG3275	phosphorelay sensor kinase activity
EPG46_RS10075	COG0789	Transcriptional regulator
EPG46_RS10085	COG1174	glycine betaine transport
EPG46_RS10090	COG1125	glycine betaine transport
EPG46_RS10095	COG1174	glycine betaine transport
EPG46_RS10100	COG1732	Glycine betaine
EPG46_RS10105	COG1472	Belongs to the glycosyl hydrolase 3 family
EPG46_RS10110	COG0277	FAD linked oxidase domain protein
EPG46_RS10115	COG1686	Belongs to the peptidase S11 family
EPG46_RS10125	COG0586	Pfam SNARE associated Golgi protein
EPG46_RS10130	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS10145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPG46_RS10155	COG1346	cytolysis
EPG46_RS10165	COG2949	membrane
EPG46_RS10175	COG0493	'glutamate synthase
EPG46_RS10180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EPG46_RS10180	COG0167	dihydroorotate dehydrogenase activity
EPG46_RS10185	COG4211	Belongs to the binding-protein-dependent transport system permease family
EPG46_RS10190	COG1129	ABC transporter
EPG46_RS10195	COG1879	ABC-type sugar transport system periplasmic component
EPG46_RS10200	COG1609	Transcriptional regulator
EPG46_RS10205	COG2311	Membrane
EPG46_RS10220	COG4771	TonB-dependent receptor
EPG46_RS10225	COG0833	amino acid
EPG46_RS10230	COG0583	DNA-binding transcription factor activity
EPG46_RS10235	COG2855	membrane
EPG46_RS10245	COG1522	sequence-specific DNA binding
EPG46_RS10245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS10250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPG46_RS10260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EPG46_RS10265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPG46_RS10270	COG2313	pseudouridylate synthase activity
EPG46_RS10275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS10280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS10280	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EPG46_RS10280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS10285	COG1105	Belongs to the carbohydrate kinase PfkB family
EPG46_RS10290	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS10290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS10295	COG2814	Major facilitator Superfamily
EPG46_RS10310	COG0246	Mannitol dehydrogenase
EPG46_RS10315	COG0523	cobalamin synthesis protein
EPG46_RS10320	COG0671	phosphoesterase, PA-phosphatase related
EPG46_RS10325	COG0791	NLP P60 protein
EPG46_RS10330	COG2200	EAL domain
EPG46_RS10335	COG4166	transmembrane transport
EPG46_RS10340	COG4174	ABC transporter (Permease)
EPG46_RS10345	COG4239	(ABC) transporter, permease
EPG46_RS10350	COG4172	Belongs to the ABC transporter superfamily
EPG46_RS10360	COG2814	Major facilitator Superfamily
EPG46_RS10365	COG1187	pseudouridine synthase activity
EPG46_RS10370	COG1061	Type III restriction enzyme res subunit
EPG46_RS10390	COG3083	sulfuric ester hydrolase activity
EPG46_RS10405	COG2197	response regulator
EPG46_RS10410	COG4235	cytochrome complex assembly
EPG46_RS10410	COG3088	subunit of a heme lyase
EPG46_RS10415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EPG46_RS10420	COG1138	Cytochrome C-type biogenesis protein
EPG46_RS10430	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EPG46_RS10435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EPG46_RS10440	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EPG46_RS10445	COG4133	protoheme IX ABC transporter activity
EPG46_RS10450	COG3005	denitrification pathway
EPG46_RS10455	COG3043	anaerobic respiration
EPG46_RS10460	COG0348	domain, Protein
EPG46_RS10465	COG0437	4 iron, 4 sulfur cluster binding
EPG46_RS10475	COG3062	negative regulation of establishment of protein localization
EPG46_RS10480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS10480	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS10500	COG4615	Cyclic peptide transporter
EPG46_RS10505	COG3145	DNA-N1-methyladenine dioxygenase activity
EPG46_RS10510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPG46_RS10510	COG2169	Transcriptional regulator
EPG46_RS10515	COG1477	protein flavinylation
EPG46_RS10520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EPG46_RS10525	COG2198	Histidine kinase
EPG46_RS10525	COG0642	Histidine kinase
EPG46_RS10530	COG2197	response regulator
EPG46_RS10535	COG0784	Response regulator, receiver
EPG46_RS10535	COG2205	protein histidine kinase activity
EPG46_RS10540	COG3852	Histidine kinase
EPG46_RS10545	COG2204	response regulator
EPG46_RS10550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EPG46_RS10555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EPG46_RS10560	COG2031	fatty acid transporter
EPG46_RS10565	COG0183	Belongs to the thiolase family
EPG46_RS10570	COG4676	Protein conserved in bacteria
EPG46_RS10575	COG5445	Predicted secreted protein (DUF2300)
EPG46_RS10580	COG2373	Large extracellular alpha-helical protein
EPG46_RS10585	COG3234	Protein of unknown function (DUF1175)
EPG46_RS10590	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
EPG46_RS10595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPG46_RS10605	COG3468	outer membrane autotransporter barrel domain protein
EPG46_RS10610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPG46_RS10615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPG46_RS10620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPG46_RS10625	COG3642	lipopolysaccharide core region biosynthetic process
EPG46_RS10650	COG0584	glycerophosphoryl diester phosphodiesterase
EPG46_RS10655	COG2271	Major facilitator Superfamily
EPG46_RS10660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EPG46_RS10670	COG0247	lactate metabolic process
EPG46_RS10675	COG5464	transposase or invertase
EPG46_RS10690	COG2271	Major facilitator Superfamily
EPG46_RS10765	COG0318	PFAM AMP-dependent synthetase and ligase
EPG46_RS10775	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EPG46_RS10790	COG1169	isochorismate synthase
EPG46_RS10795	COG4575	ribosome binding
EPG46_RS10800	COG2153	protein acetylation
EPG46_RS10830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EPG46_RS10835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EPG46_RS10845	COG0839	Belongs to the complex I subunit 6 family
EPG46_RS10860	COG1034	ATP synthesis coupled electron transport
EPG46_RS10865	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EPG46_RS10870	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EPG46_RS10890	COG0583	DNA-binding transcription factor activity
EPG46_RS10900	COG0436	Aminotransferase
EPG46_RS10910	COG0490	domain, Protein
EPG46_RS10910	COG0471	metal ion transport
EPG46_RS10915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPG46_RS10930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPG46_RS10935	COG0857	belongs to the CobB CobQ family
EPG46_RS10935	COG0280	phosphate acetyltransferase
EPG46_RS10940	COG1288	antiporter activity
EPG46_RS10945	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EPG46_RS10950	COG0622	Phosphoesterase
EPG46_RS10955	COG0625	glutathione transferase activity
EPG46_RS10960	COG0625	glutathione transferase activity
EPG46_RS10965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPG46_RS10970	COG1090	epimerase
EPG46_RS10975	COG5464	transposase or invertase
EPG46_RS10980	COG4598	ABC transporter
EPG46_RS10985	COG4160	amino acid transport
EPG46_RS10990	COG4215	(ABC) transporter
EPG46_RS10995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPG46_RS11000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPG46_RS11005	COG0163	prenyltransferase activity
EPG46_RS11010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPG46_RS11015	COG1286	toxin biosynthetic process
EPG46_RS11020	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EPG46_RS11025	COG0285	dihydrofolate synthase activity
EPG46_RS11035	COG0586	Pfam SNARE associated Golgi protein
EPG46_RS11045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPG46_RS11060	COG2814	Major facilitator Superfamily
EPG46_RS11065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EPG46_RS11080	COG3101	peptidyl-lysine hydroxylation
EPG46_RS11085	COG0730	response to heat
EPG46_RS11100	COG2890	protein-(glutamine-N5) methyltransferase activity
EPG46_RS11115	COG3539	Fimbrial protein
EPG46_RS11120	COG3539	Fimbrial protein
EPG46_RS11125	COG3539	Fimbrial protein
EPG46_RS11130	COG3121	Chaperone
EPG46_RS11140	COG3539	Fimbrial protein
EPG46_RS11145	COG2062	phosphohistidine phosphatase, SixA
EPG46_RS11160	COG3691	Protein conserved in bacteria
EPG46_RS11165	COG2067	long-chain fatty acid transport protein
EPG46_RS11175	COG2853	Lipoprotein
EPG46_RS11180	COG2116	formate transmembrane transporter activity
EPG46_RS11215	COG3344	reverse transcriptase
EPG46_RS11315	COG1802	Transcriptional regulator
EPG46_RS11315	COG4626	Terminase
EPG46_RS11385	COG1403	HNH endonuclease
EPG46_RS11390	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EPG46_RS11400	COG1846	Transcriptional regulator
EPG46_RS11455	COG0582	viral genome integration into host DNA
EPG46_RS11495	COG0477	Major facilitator Superfamily
EPG46_RS11500	COG1566	PFAM secretion protein HlyD family protein
EPG46_RS11505	COG2197	response regulator
EPG46_RS11510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPG46_RS11510	COG2198	Histidine kinase
EPG46_RS11510	COG0784	Response regulator, receiver
EPG46_RS11510	COG2205	protein histidine kinase activity
EPG46_RS11515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EPG46_RS11520	COG0679	Auxin Efflux Carrier
EPG46_RS11525	COG0028	Belongs to the TPP enzyme family
EPG46_RS11555	COG1560	Kdo2-lipid A biosynthetic process
EPG46_RS11565	COG0436	Aminotransferase
EPG46_RS11570	COG3275	phosphorelay sensor kinase activity
EPG46_RS11575	COG3279	Response regulator of the LytR AlgR family
EPG46_RS11585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS11585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPG46_RS11585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS11590	COG1363	Peptidase, m42
EPG46_RS11595	COG0006	proline dipeptidase activity
EPG46_RS11600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS11605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS11630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPG46_RS11635	COG2200	EAL domain
EPG46_RS11635	COG2199	diguanylate cyclase activity
EPG46_RS11650	COG3415	Transposase
EPG46_RS11655	COG3415	Transposase
EPG46_RS11690	COG0583	DNA-binding transcription factor activity
EPG46_RS11700	COG2211	Major facilitator Superfamily
EPG46_RS11705	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EPG46_RS11715	COG0583	DNA-binding transcription factor activity
EPG46_RS11720	COG0385	Bile acid
EPG46_RS11725	COG3530	Putative quorum-sensing-regulated virulence factor
EPG46_RS11745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EPG46_RS11750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS11755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPG46_RS11760	COG2190	(PTS) system
EPG46_RS11775	COG4884	unkown
EPG46_RS11775	COG3831	ATPase activity
EPG46_RS11780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EPG46_RS11785	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EPG46_RS11790	COG4208	sulfate ABC transporter
EPG46_RS11795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EPG46_RS11800	COG4150	thiosulfate binding
EPG46_RS11805	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS11820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS11820	COG1263	PTS System
EPG46_RS11825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EPG46_RS11830	COG2837	iron assimilation
EPG46_RS11845	COG0456	acetyltransferase
EPG46_RS11850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EPG46_RS11860	COG2207	Transcriptional regulator
EPG46_RS11865	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EPG46_RS11870	COG4816	utilization protein
EPG46_RS11880	COG4303	Ethanolamine ammonia lyase large subunit
EPG46_RS11885	COG4819	ethanolamine utilization protein
EPG46_RS11890	COG3192	ethanolamine utilization protein
EPG46_RS11895	COG1454	alcohol dehydrogenase
EPG46_RS11900	COG4820	ethanolamine utilization protein (EutJ)
EPG46_RS11905	COG1012	belongs to the aldehyde dehydrogenase family
EPG46_RS11910	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EPG46_RS11915	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EPG46_RS11920	COG0280	phosphate acetyltransferase
EPG46_RS11925	COG4812	Cobalamin adenosyltransferase
EPG46_RS11930	COG4766	ethanolamine catabolic process
EPG46_RS11935	COG4917	ethanolamine utilization protein
EPG46_RS11940	COG4810	utilization protein
EPG46_RS11945	COG0281	malic enzyme
EPG46_RS11945	COG0280	phosphate acetyltransferase
EPG46_RS11950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPG46_RS11955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPG46_RS11960	COG5342	invasion associated locus B
EPG46_RS11970	COG0493	'glutamate synthase
EPG46_RS11970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS11975	COG3850	Histidine kinase
EPG46_RS11980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPG46_RS11990	COG1393	Belongs to the ArsC family
EPG46_RS12005	COG0400	carboxylic ester hydrolase activity
EPG46_RS12010	COG1444	tRNA N-acetyltransferase activity
EPG46_RS12015	COG2321	neutral zinc metallopeptidase
EPG46_RS12025	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EPG46_RS12035	COG2716	regulation of RNA biosynthetic process
EPG46_RS12040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EPG46_RS12045	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS12050	COG0651	ATP synthesis coupled electron transport
EPG46_RS12055	COG0650	Formate hydrogenlyase subunit 4
EPG46_RS12060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EPG46_RS12065	COG4237	Hydrogenase 4 membrane
EPG46_RS12070	COG0651	ATP synthesis coupled electron transport
EPG46_RS12075	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EPG46_RS12075	COG3261	NADH dehydrogenase
EPG46_RS12080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EPG46_RS12085	COG3260	NADH ubiquinone oxidoreductase 20
EPG46_RS12095	COG3604	Transcriptional regulator
EPG46_RS12100	COG2116	formate transmembrane transporter activity
EPG46_RS12105	COG0628	permease
EPG46_RS12110	COG4783	chaperone-mediated protein folding
EPG46_RS12115	COG1393	Belongs to the ArsC family
EPG46_RS12125	COG2233	PERMEase
EPG46_RS12140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EPG46_RS12145	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EPG46_RS12150	COG0248	Ppx GppA phosphatase
EPG46_RS12155	COG2200	EAL domain
EPG46_RS12170	COG3133	Outer membrane lipoprotein
EPG46_RS12185	COG0516	GMP reductase activity
EPG46_RS12185	COG0517	IMP dehydrogenase activity
EPG46_RS12195	COG1645	bacterial-type flagellum-dependent swarming motility
EPG46_RS12210	COG2976	Protein conserved in bacteria
EPG46_RS12240	COG4953	penicillin-binding protein 1C
EPG46_RS12245	COG2373	Large extracellular alpha-helical protein
EPG46_RS12250	COG2897	thiosulfate sulfurtransferase activity
EPG46_RS12265	COG2975	iron-sulfur cluster assembly
EPG46_RS12270	COG0633	Ferredoxin
EPG46_RS12290	COG0822	iron-sulfur transferase activity
EPG46_RS12310	COG0483	inositol monophosphate 1-phosphatase activity
EPG46_RS12315	COG1073	alpha beta
EPG46_RS12320	COG3711	transcriptional antiterminator
EPG46_RS12325	COG2814	Major facilitator Superfamily
EPG46_RS12330	COG0583	DNA-binding transcription factor activity
EPG46_RS12335	COG4638	Rieske (2fe-2S)
EPG46_RS12360	COG2259	Doxx family
EPG46_RS12365	COG2017	converts alpha-aldose to the beta-anomer
EPG46_RS12370	COG1063	alcohol dehydrogenase
EPG46_RS12375	COG1172	Belongs to the binding-protein-dependent transport system permease family
EPG46_RS12380	COG1129	ABC transporter
EPG46_RS12385	COG1879	ABC-type sugar transport system periplasmic component
EPG46_RS12390	COG0457	Tetratricopeptide repeat
EPG46_RS12395	COG1940	carbohydrate kinase activity
EPG46_RS12405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPG46_RS12405	COG1017	nitric oxide dioxygenase activity
EPG46_RS12410	COG0347	Belongs to the P(II) protein family
EPG46_RS12415	COG2204	response regulator
EPG46_RS12420	COG3170	Tfp pilus assembly protein FimV
EPG46_RS12425	COG2205	protein histidine kinase activity
EPG46_RS12430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPG46_RS12430	COG0047	phosphoribosylformylglycinamidine synthase activity
EPG46_RS12445	COG0560	Phosphoserine phosphatase
EPG46_RS12450	COG1737	Transcriptional regulator
EPG46_RS12455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS12470	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EPG46_RS12490	COG0681	Belongs to the peptidase S26 family
EPG46_RS12500	COG3086	response to oxidative stress
EPG46_RS12505	COG3026	antisigma factor binding
EPG46_RS12510	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EPG46_RS12515	COG1595	DNA-templated transcription, initiation
EPG46_RS12525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EPG46_RS12535	COG0513	Belongs to the DEAD box helicase family
EPG46_RS12540	COG0583	DNA-binding transcription factor activity
EPG46_RS12560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPG46_RS12565	COG3118	belongs to the thioredoxin family
EPG46_RS12575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPG46_RS12575	COG0045	succinate-CoA ligase (ADP-forming) activity
EPG46_RS12575	COG1042	CoA-binding domain protein
EPG46_RS12580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPG46_RS12585	COG5544	Lipoprotein
EPG46_RS12590	COG0477	Major facilitator Superfamily
EPG46_RS12615	COG0542	response to heat
EPG46_RS12625	COG0564	pseudouridine synthase activity
EPG46_RS12630	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPG46_RS12635	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPG46_RS12645	COG0077	Prephenate dehydratase
EPG46_RS12645	COG1605	Chorismate mutase
EPG46_RS12650	COG1605	Chorismate mutase
EPG46_RS12650	COG0287	Prephenate dehydrogenase
EPG46_RS12655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPG46_RS12670	COG2199	diguanylate cyclase activity
EPG46_RS12675	COG2885	chlorophyll binding
EPG46_RS12700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPG46_RS12705	COG4137	Cytochrome C assembly protein
EPG46_RS12710	COG4536	flavin adenine dinucleotide binding
EPG46_RS12725	COG0497	DNA recombination
EPG46_RS12730	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPG46_RS12740	COG2867	negative regulation of translational initiation
EPG46_RS12755	COG3468	outer membrane autotransporter barrel domain protein
EPG46_RS12780	COG0366	Alpha amylase catalytic
EPG46_RS12795	COG0579	oxidoreductase
EPG46_RS12800	COG1012	belongs to the aldehyde dehydrogenase family
EPG46_RS12805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPG46_RS12810	COG1113	amino acid transport
EPG46_RS12815	COG1802	Transcriptional regulator
EPG46_RS12820	COG1652	LysM domain
EPG46_RS12825	COG0401	homolog of Blt101
EPG46_RS12830	COG0640	Transcriptional regulator
EPG46_RS12835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPG46_RS12840	COG2916	Histone family protein nucleoid-structuring protein H-NS
EPG46_RS12855	COG4575	ribosome binding
EPG46_RS12860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EPG46_RS12870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPG46_RS12875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPG46_RS12880	COG4175	Glycine betaine
EPG46_RS12885	COG4176	ABC-type proline glycine betaine transport system permease component
EPG46_RS12890	COG2113	Glycine betaine
EPG46_RS12895	COG2814	Major facilitator Superfamily
EPG46_RS12900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EPG46_RS12910	COG1846	Transcriptional regulator
EPG46_RS12915	COG1566	PFAM secretion protein HlyD family protein
EPG46_RS12920	COG2814	Major facilitator Superfamily
EPG46_RS12935	COG1238	metal cluster binding
EPG46_RS12940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPG46_RS12970	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EPG46_RS12990	COG1546	Belongs to the CinA family
EPG46_RS12995	COG2951	lytic endotransglycosylase activity
EPG46_RS13000	COG3730	PTS system glucitol sorbitol-specific
EPG46_RS13005	COG3732	PTS system glucitol sorbitol-specific
EPG46_RS13010	COG3731	PTS system glucitol sorbitol-specific IIA component
EPG46_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS13020	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS13025	COG1349	DNA-binding transcription factor activity
EPG46_RS13030	COG0517	IMP dehydrogenase activity
EPG46_RS13030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EPG46_RS13050	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EPG46_RS13055	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS13060	COG1609	Transcriptional regulator
EPG46_RS13065	COG1263	PTS System
EPG46_RS13065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS13070	COG2723	6-phospho-beta-galactosidase activity
EPG46_RS13075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EPG46_RS13085	COG3260	NADH ubiquinone oxidoreductase 20
EPG46_RS13090	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EPG46_RS13095	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EPG46_RS13095	COG3261	NADH dehydrogenase
EPG46_RS13100	COG0650	Formate hydrogenlyase subunit 4
EPG46_RS13105	COG0651	ATP synthesis coupled electron transport
EPG46_RS13110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS13120	COG0375	protein maturation
EPG46_RS13125	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EPG46_RS13130	COG0298	carbon dioxide binding
EPG46_RS13135	COG0409	Hydrogenase expression formation protein
EPG46_RS13140	COG0309	Hydrogenase expression formation protein (HypE)
EPG46_RS13145	COG3604	Transcriptional regulator
EPG46_RS13165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EPG46_RS13170	COG1349	DNA-binding transcription factor activity
EPG46_RS13175	COG2084	Dehydrogenase
EPG46_RS13180	COG3395	kinase activity
EPG46_RS13185	COG0235	Class ii aldolase
EPG46_RS13190	COG3622	Belongs to the hyi family
EPG46_RS13195	COG2610	gluconate transmembrane transporter activity
EPG46_RS13200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPG46_RS13205	COG1388	LysM domain
EPG46_RS13205	COG4942	peptidase
EPG46_RS13260	COG2234	aminopeptidase activity
EPG46_RS13265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EPG46_RS13270	COG1518	maintenance of DNA repeat elements
EPG46_RS13285	COG1857	crispr-associated protein
EPG46_RS13300	COG1203	CRISPR-associated helicase, Cas3
EPG46_RS13310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EPG46_RS13320	COG0720	synthase
EPG46_RS13325	COG0644	oxidoreductase
EPG46_RS13330	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EPG46_RS13335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EPG46_RS13340	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EPG46_RS13345	COG2086	electron transfer activity
EPG46_RS13350	COG0477	Major facilitator Superfamily
EPG46_RS13355	COG0277	FAD linked oxidase domain protein
EPG46_RS13360	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS13365	COG2223	nitrite transmembrane transporter activity
EPG46_RS13370	COG1070	Carbohydrate kinase
EPG46_RS13375	COG0602	queuosine metabolic process
EPG46_RS13385	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EPG46_RS13400	COG3956	TIGRFAM MazG family protein
EPG46_RS13405	COG2337	Toxic component of a toxin-antitoxin (TA) module
EPG46_RS13410	COG2336	PFAM SpoVT AbrB
EPG46_RS13415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPG46_RS13420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPG46_RS13425	COG2205	protein histidine kinase activity
EPG46_RS13425	COG3437	response regulator, receiver
EPG46_RS13425	COG3850	Histidine kinase
EPG46_RS13425	COG4999	Histidine kinase
EPG46_RS13430	COG4948	Mandelate Racemase Muconate Lactonizing
EPG46_RS13435	COG4948	Mandelate Racemase Muconate Lactonizing
EPG46_RS13440	COG2271	Major facilitator Superfamily
EPG46_RS13445	COG0716	FMN binding
EPG46_RS13450	COG0564	pseudouridine synthase activity
EPG46_RS13455	COG3098	single-species biofilm formation
EPG46_RS13470	COG1611	Belongs to the LOG family
EPG46_RS13475	COG0814	amino acid
EPG46_RS13480	COG1760	l-serine dehydratase
EPG46_RS13490	COG1454	alcohol dehydrogenase
EPG46_RS13495	COG0235	Class ii aldolase
EPG46_RS13500	COG0738	Major facilitator superfamily
EPG46_RS13510	COG1070	Carbohydrate kinase
EPG46_RS13520	COG1349	DNA-binding transcription factor activity
EPG46_RS13530	COG2363	Small membrane protein
EPG46_RS13535	COG0583	DNA-binding transcription factor activity
EPG46_RS13545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPG46_RS13550	COG2166	iron-sulfur cluster assembly
EPG46_RS13555	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EPG46_RS13560	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EPG46_RS13580	COG0860	N-Acetylmuramoyl-L-alanine amidase
EPG46_RS13585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EPG46_RS13585	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EPG46_RS13590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EPG46_RS13595	COG1074	ATP-dependent DNA helicase activity
EPG46_RS13600	COG1025	Belongs to the peptidase M16 family
EPG46_RS13605	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EPG46_RS13610	COG4967	type IV pilus modification protein PilV
EPG46_RS13620	COG4795	General secretion pathway protein
EPG46_RS13625	COG2165	general secretion pathway protein
EPG46_RS13640	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
EPG46_RS13655	COG0861	Integral membrane protein TerC family
EPG46_RS13665	COG0667	Aldo Keto reductase
EPG46_RS13680	COG1609	Transcriptional regulator
EPG46_RS13690	COG0583	DNA-binding transcription factor activity
EPG46_RS13695	COG1794	racemase activity, acting on amino acids and derivatives
EPG46_RS13700	COG2814	Major facilitator Superfamily
EPG46_RS13705	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS13715	COG0183	Belongs to the thiolase family
EPG46_RS13720	COG0814	amino acid
EPG46_RS13725	COG2771	luxR family
EPG46_RS13730	COG3710	Transcriptional regulator
EPG46_RS13755	COG0457	Tetratricopeptide repeat
EPG46_RS13760	COG3710	Transcriptional regulator
EPG46_RS13760	COG0457	Tetratricopeptide repeat
EPG46_RS13850	COG4942	peptidase
EPG46_RS13855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EPG46_RS13860	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EPG46_RS13865	COG2080	2 iron, 2 sulfur cluster binding
EPG46_RS13875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EPG46_RS13880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EPG46_RS13885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EPG46_RS13895	COG0549	Belongs to the carbamate kinase family
EPG46_RS13900	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EPG46_RS13900	COG3608	succinylglutamate desuccinylase aspartoacylase
EPG46_RS13905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPG46_RS13910	COG2068	MobA-Related Protein
EPG46_RS13915	COG0493	'glutamate synthase
EPG46_RS13915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS13920	COG0402	S-adenosylhomocysteine deaminase activity
EPG46_RS13925	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EPG46_RS13930	COG2080	2 iron, 2 sulfur cluster binding
EPG46_RS13930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EPG46_RS13935	COG2233	PERMEase
EPG46_RS13940	COG0402	S-adenosylhomocysteine deaminase activity
EPG46_RS13945	COG2252	PERMEase
EPG46_RS13950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS13960	COG2233	PERMEase
EPG46_RS13980	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EPG46_RS13990	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EPG46_RS13995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EPG46_RS14000	COG4974	Belongs to the 'phage' integrase family
EPG46_RS14005	COG0716	FMN binding
EPG46_RS14015	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EPG46_RS14025	COG1272	protein, Hemolysin III
EPG46_RS14035	COG2723	6-phospho-beta-galactosidase activity
EPG46_RS14040	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS14065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EPG46_RS14070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EPG46_RS14075	COG0006	proline dipeptidase activity
EPG46_RS14095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EPG46_RS14105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EPG46_RS14125	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EPG46_RS14125	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EPG46_RS14130	COG1703	isobutyryl-CoA mutase activity
EPG46_RS14135	COG1024	Enoyl-CoA hydratase
EPG46_RS14140	COG0427	acetyl-CoA hydrolase
EPG46_RS14145	COG0583	DNA-binding transcription factor activity
EPG46_RS14150	COG2968	Membrane
EPG46_RS14155	COG1279	arginine transmembrane transporter activity
EPG46_RS14160	COG0668	transmembrane transport
EPG46_RS14165	COG0191	fructose-bisphosphate aldolase activity
EPG46_RS14180	COG1072	(Pantothenic acid kinase))
EPG46_RS14185	COG3722	fumarate hydratase activity
EPG46_RS14190	COG1494	fructose-1,6-bisphosphatase
EPG46_RS14195	COG1063	alcohol dehydrogenase
EPG46_RS14200	COG2213	PTS system mannitol-specific
EPG46_RS14205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS14210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPG46_RS14215	COG0501	Belongs to the peptidase M48B family
EPG46_RS14225	COG1166	arginine decarboxylase activity
EPG46_RS14245	COG2814	Major facilitator Superfamily
EPG46_RS14255	COG2356	endonuclease I
EPG46_RS14260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EPG46_RS14265	COG0189	ligase activity
EPG46_RS14280	COG2805	Type II/IV secretion system protein
EPG46_RS14285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EPG46_RS14290	COG0762	integral membrane protein
EPG46_RS14300	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPG46_RS14305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EPG46_RS14315	COG0252	asparaginase activity
EPG46_RS14325	COG3171	Protein conserved in bacteria
EPG46_RS14335	COG1194	a g-specific adenine glycosylase
EPG46_RS14350	COG2211	Major facilitator Superfamily
EPG46_RS14355	COG1982	Orn Lys Arg decarboxylase major
EPG46_RS14360	COG1811	Na channel or pump
EPG46_RS14370	COG0582	viral genome integration into host DNA
EPG46_RS14375	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EPG46_RS14375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPG46_RS14380	COG2194	sulfuric ester hydrolase activity
EPG46_RS14495	COG3596	GTP binding
EPG46_RS14500	COG2378	regulation of single-species biofilm formation
EPG46_RS14525	COG2003	Belongs to the UPF0758 family
EPG46_RS14565	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EPG46_RS14580	COG4795	General secretion pathway protein
EPG46_RS14595	COG2165	general secretion pathway protein
EPG46_RS14600	COG1459	type II secretion system
EPG46_RS14615	COG3031	protein transport across the cell outer membrane
EPG46_RS14625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EPG46_RS14635	COG3064	Membrane
EPG46_RS14640	COG1620	l-lactate permease
EPG46_RS14645	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EPG46_RS14650	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EPG46_RS14655	COG0247	lactate metabolic process
EPG46_RS14660	COG0277	FAD linked oxidase domain protein
EPG46_RS14665	COG0277	FAD linked oxidase domain protein
EPG46_RS14670	COG2186	Transcriptional regulator
EPG46_RS14675	COG0456	acetyltransferase
EPG46_RS14680	COG0318	PFAM AMP-dependent synthetase and ligase
EPG46_RS14690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPG46_RS14695	COG0156	8-amino-7-oxononanoate synthase activity
EPG46_RS14705	COG0795	lipopolysaccharide-transporting ATPase activity
EPG46_RS14710	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EPG46_RS14720	COG2244	polysaccharide biosynthetic process
EPG46_RS14725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPG46_RS14730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPG46_RS14735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPG46_RS14740	COG0306	phosphate transporter
EPG46_RS14745	COG0754	glutathionylspermidine amidase activity
EPG46_RS14750	COG0625	glutathione transferase activity
EPG46_RS14755	COG0298	carbon dioxide binding
EPG46_RS14765	COG1773	rubredoxin
EPG46_RS14770	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EPG46_RS14775	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EPG46_RS14780	COG5557	Pfam Polysulphide reductase, NrfD
EPG46_RS14785	COG0437	4 iron, 4 sulfur cluster binding
EPG46_RS14790	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EPG46_RS14805	COG0667	Aldo Keto reductase
EPG46_RS14815	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS14820	COG0848	biopolymer transport protein
EPG46_RS14825	COG0811	peptide transport
EPG46_RS14830	COG0626	cystathionine gamma-synthase activity
EPG46_RS14835	COG0586	Pfam SNARE associated Golgi protein
EPG46_RS14840	COG2207	Transcriptional regulator
EPG46_RS14845	COG1979	alcohol dehydrogenase
EPG46_RS14850	COG0656	L-ascorbic acid biosynthetic process
EPG46_RS14860	COG4238	major outer membrane lipoprotein
EPG46_RS14865	COG1032	radical SAM domain protein
EPG46_RS14870	COG2132	Multicopper oxidase
EPG46_RS14875	COG0204	Acyl-transferase
EPG46_RS14880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPG46_RS14885	COG4166	transmembrane transport
EPG46_RS14890	COG2944	sequence-specific DNA binding
EPG46_RS14900	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EPG46_RS14905	COG3111	PFAM Bacterial OB fold (BOF) protein
EPG46_RS14910	COG0745	RESPONSE REGULATOR receiver
EPG46_RS14915	COG0642	Histidine kinase
EPG46_RS14930	COG2249	NAD(P)H dehydrogenase (quinone) activity
EPG46_RS14935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EPG46_RS14940	COG0187	DNA topoisomerase II activity
EPG46_RS14945	COG3150	esterase
EPG46_RS14950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EPG46_RS14955	COG3151	Protein conserved in bacteria
EPG46_RS14960	COG0494	nUDIX hydrolase
EPG46_RS14965	COG1538	Outer membrane efflux protein
EPG46_RS14975	COG0754	glutathionylspermidine amidase activity
EPG46_RS14980	COG3384	dioxygenase
EPG46_RS15000	COG2960	long-chain fatty acid transporting porin activity
EPG46_RS15005	COG3539	Fimbrial protein
EPG46_RS15015	COG3121	Chaperone
EPG46_RS15020	COG3539	Fimbrial protein
EPG46_RS15030	COG1585	Membrane protein implicated in regulation of membrane protease activity
EPG46_RS15035	COG2268	Band 7 protein
EPG46_RS15060	COG3025	triphosphatase activity
EPG46_RS15065	COG4991	sh3 domain protein
EPG46_RS15080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPG46_RS15105	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EPG46_RS15110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EPG46_RS15115	COG0471	metal ion transport
EPG46_RS15125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EPG46_RS15130	COG0358	DNA primase activity
EPG46_RS15135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPG46_RS15150	COG2375	cellular response to nickel ion
EPG46_RS15155	COG1695	Transcriptional regulator
EPG46_RS15160	COG0840	transmembrane signaling receptor activity
EPG46_RS15170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPG46_RS15175	COG1609	Transcriptional regulator
EPG46_RS15180	COG3250	beta-galactosidase activity
EPG46_RS15185	COG2731	YhcH YjgK YiaL family protein
EPG46_RS15190	COG0531	amino acid
EPG46_RS15200	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EPG46_RS15200	COG3408	Glycogen debranching enzyme
EPG46_RS15205	COG1902	pentaerythritol trinitrate reductase activity
EPG46_RS15205	COG0446	pyridine nucleotide-disulphide oxidoreductase
EPG46_RS15210	COG5499	transcription regulator containing HTH domain
EPG46_RS15215	COG4680	protein conserved in bacteria
EPG46_RS15225	COG1451	nucleotide metabolic process
EPG46_RS15230	COG2949	membrane
EPG46_RS15235	COG0673	inositol 2-dehydrogenase activity
EPG46_RS15240	COG0861	Integral membrane protein TerC family
EPG46_RS15245	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EPG46_RS15255	COG2721	sulfolactate sulfo-lyase activity
EPG46_RS15265	COG2271	Major facilitator Superfamily
EPG46_RS15270	COG2186	Transcriptional regulator
EPG46_RS15275	COG0586	Pfam SNARE associated Golgi protein
EPG46_RS15285	COG1422	Protein of unknown function (DUF1090)
EPG46_RS15290	COG4575	ribosome binding
EPG46_RS15295	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EPG46_RS15305	COG2259	Doxx family
EPG46_RS15310	COG0435	Glutathione S-transferase
EPG46_RS15315	COG3152	Membrane
EPG46_RS15320	COG3152	Membrane
EPG46_RS15325	COG0583	DNA-binding transcription factor activity
EPG46_RS15330	COG1741	Belongs to the pirin family
EPG46_RS15345	COG0814	amino acid
EPG46_RS15350	COG1760	l-serine dehydratase
EPG46_RS15355	COG0251	oxidation-reduction process
EPG46_RS15360	COG1882	Formate acetyltransferase
EPG46_RS15365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPG46_RS15375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EPG46_RS15380	COG0583	DNA-binding transcription factor activity
EPG46_RS15405	COG1929	Belongs to the glycerate kinase type-1 family
EPG46_RS15410	COG2084	Dehydrogenase
EPG46_RS15420	COG2271	Major facilitator Superfamily
EPG46_RS15425	COG2721	sulfolactate sulfo-lyase activity
EPG46_RS15430	COG2002	toxin-antitoxin pair type II binding
EPG46_RS15440	COG1349	DNA-binding transcription factor activity
EPG46_RS15450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS15460	COG3716	PTS system mannose fructose sorbose family IID component
EPG46_RS15465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS15470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EPG46_RS15475	COG2222	sugar isomerase
EPG46_RS15485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS15500	COG3716	PTS system mannose fructose sorbose family IID component
EPG46_RS15505	COG0363	glucosamine-6-phosphate deaminase activity
EPG46_RS15510	COG3539	Fimbrial protein
EPG46_RS15515	COG3121	Chaperone
EPG46_RS15520	COG3188	usher protein
EPG46_RS15525	COG3539	Fimbrial protein
EPG46_RS15530	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPG46_RS15535	COG3107	peptidoglycan biosynthetic process
EPG46_RS15550	COG2823	Periplasmic or secreted lipoprotein
EPG46_RS15555	COG0701	Predicted permease
EPG46_RS15560	COG0702	epimerase
EPG46_RS15565	COG0693	protein deglycase activity
EPG46_RS15580	COG3153	acetyltransferase
EPG46_RS15585	COG3154	lipid carrier protein
EPG46_RS15590	COG0826	peptidase U32
EPG46_RS15595	COG0826	peptidase U32
EPG46_RS15600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPG46_RS15605	COG0814	amino acid
EPG46_RS15610	COG0513	Belongs to the DEAD box helicase family
EPG46_RS15650	COG0195	Participates in both transcription termination and antitermination
EPG46_RS15670	COG2194	sulfuric ester hydrolase activity
EPG46_RS15680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EPG46_RS15690	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EPG46_RS15695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPG46_RS15705	COG1534	Rna-binding protein
EPG46_RS15710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EPG46_RS15715	COG2027	D-alanyl-D-alanine carboxypeptidase
EPG46_RS15725	COG0697	spore germination
EPG46_RS15740	COG0142	geranyltranstransferase activity
EPG46_RS15745	COG3423	Transcriptional regulator
EPG46_RS15755	COG5007	Belongs to the BolA IbaG family
EPG46_RS15760	COG3113	response to antibiotic
EPG46_RS15765	COG2854	intermembrane phospholipid transfer
EPG46_RS15770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EPG46_RS15775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EPG46_RS15780	COG1127	ABC transporter
EPG46_RS15785	COG0530	calcium, potassium:sodium antiporter activity
EPG46_RS15790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EPG46_RS15790	COG0517	IMP dehydrogenase activity
EPG46_RS15795	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EPG46_RS15800	COG3117	lipopolysaccharide transmembrane transporter activity
EPG46_RS15805	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EPG46_RS15810	COG1137	ATPase activity
EPG46_RS15815	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EPG46_RS15820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPG46_RS15835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS15840	COG0515	serine threonine protein kinase
EPG46_RS15850	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EPG46_RS15855	COG5002	protein histidine kinase activity
EPG46_RS15855	COG0784	Response regulator, receiver
EPG46_RS15855	COG2198	Histidine kinase
EPG46_RS15860	COG1242	4 iron, 4 sulfur cluster binding
EPG46_RS15865	COG0070	glutamate synthase
EPG46_RS15865	COG0069	glutamate synthase activity
EPG46_RS15865	COG0067	glutamate synthase
EPG46_RS15870	COG0493	'glutamate synthase
EPG46_RS15875	COG3539	Fimbrial protein
EPG46_RS15880	COG3121	Chaperone
EPG46_RS15885	COG3188	usher protein
EPG46_RS15895	COG3539	Fimbrial protein
EPG46_RS15910	COG4804	nuclease activity
EPG46_RS15915	COG2731	YhcH YjgK YiaL family protein
EPG46_RS15945	COG3069	C4-dicarboxylate transmembrane transporter activity
EPG46_RS15950	COG2969	positive regulation of protein catabolic process
EPG46_RS15955	COG0625	glutathione transferase activity
EPG46_RS15970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EPG46_RS15975	COG3105	Protein conserved in bacteria
EPG46_RS15980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPG46_RS15985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPG46_RS16005	COG2732	(Barnase) inhibitor
EPG46_RS16025	COG0583	DNA-binding transcription factor activity
EPG46_RS16030	COG0312	modulator of DNA gyrase
EPG46_RS16035	COG3164	Protein of unknown function
EPG46_RS16040	COG1530	ribonuclease E activity
EPG46_RS16045	COG0424	maF-like protein
EPG46_RS16050	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EPG46_RS16055	COG1792	Involved in formation and maintenance of cell shape
EPG46_RS16060	COG1077	Cell shape determining protein MreB Mrl
EPG46_RS16065	COG2199	diguanylate cyclase activity
EPG46_RS16065	COG2200	EAL domain
EPG46_RS16070	COG0604	alcohol dehydrogenase
EPG46_RS16075	COG0511	ligase activity, forming carbon-carbon bonds
EPG46_RS16080	COG0439	Biotin carboxylase
EPG46_RS16085	COG3924	membrane
EPG46_RS16090	COG4145	pantothenate transmembrane transporter activity
EPG46_RS16100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPG46_RS16110	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EPG46_RS16120	COG1309	transcriptional regulator
EPG46_RS16125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPG46_RS16130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPG46_RS16140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPG46_RS16145	COG4597	amino acid ABC transporter
EPG46_RS16150	COG0765	amino acid transport
EPG46_RS16155	COG1126	abc transporter atp-binding protein
EPG46_RS16195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EPG46_RS16215	COG0551	DNA topoisomerase type I activity
EPG46_RS16225	COG0758	DNA mediated transformation
EPG46_RS16245	COG0569	domain protein
EPG46_RS16255	COG3036	rescue of stalled ribosome
EPG46_RS16260	COG0789	Transcriptional regulator
EPG46_RS16300	COG0201	protein transport
EPG46_RS16390	COG0089	rRNA binding
EPG46_RS16415	COG3409	Peptidoglycan-binding domain 1 protein
EPG46_RS16415	COG3267	Type II secretory pathway component ExeA
EPG46_RS16420	COG3031	protein transport across the cell outer membrane
EPG46_RS16430	COG1450	Type ii and iii secretion system protein
EPG46_RS16435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EPG46_RS16440	COG1459	type II secretion system
EPG46_RS16445	COG2165	general secretion pathway protein
EPG46_RS16450	COG2165	general secretion pathway protein
EPG46_RS16455	COG2165	general secretion pathway protein
EPG46_RS16460	COG4795	General secretion pathway protein
EPG46_RS16465	COG3156	type II secretion system protein K
EPG46_RS16470	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EPG46_RS16475	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EPG46_RS16480	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EPG46_RS16485	COG2193	ferroxidase activity
EPG46_RS16490	COG2906	2 iron, 2 sulfur cluster binding
EPG46_RS16495	COG3979	chitinase
EPG46_RS16535	COG2964	Protein conserved in bacteria
EPG46_RS16540	COG0545	Peptidyl-prolyl cis-trans isomerase
EPG46_RS16550	COG1047	Peptidyl-prolyl cis-trans
EPG46_RS16555	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EPG46_RS16570	COG0488	(ABC) transporter
EPG46_RS16575	COG0429	hydrolase of the alpha beta-hydrolase fold
EPG46_RS16585	COG3954	Phosphoribulokinase
EPG46_RS16590	COG1765	OsmC-like protein
EPG46_RS16595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EPG46_RS16600	COG1289	transmembrane transporter activity
EPG46_RS16605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EPG46_RS16610	COG0512	Glutamine amidotransferase of anthranilate synthase
EPG46_RS16615	COG2184	nucleotidyltransferase activity
EPG46_RS16625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPG46_RS16635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EPG46_RS16640	COG2146	nitrite reductase [NAD(P)H] activity
EPG46_RS16645	COG2116	formate transmembrane transporter activity
EPG46_RS16660	COG0531	amino acid
EPG46_RS16665	COG2222	sugar isomerase
EPG46_RS16670	COG1082	Xylose isomerase domain protein TIM barrel
EPG46_RS16675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS16680	COG2188	Transcriptional regulator
EPG46_RS16685	COG0626	cystathionine gamma-synthase activity
EPG46_RS16700	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EPG46_RS16705	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPG46_RS16710	COG3457	Alanine racemase
EPG46_RS16720	COG2188	Transcriptional regulator
EPG46_RS16725	COG0180	Tryptophanyl-tRNA synthetase
EPG46_RS16730	COG0546	phosphoglycolate phosphatase activity
EPG46_RS16735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EPG46_RS16740	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EPG46_RS16745	COG3266	domain, Protein
EPG46_RS16760	COG4796	Type ii and iii secretion system protein
EPG46_RS16775	COG3166	PFAM Fimbrial assembly family protein
EPG46_RS16780	COG4972	Pilus assembly protein
EPG46_RS16785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EPG46_RS16790	COG0494	nUDIX hydrolase
EPG46_RS16800	COG1011	Hydrolase
EPG46_RS16805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EPG46_RS16815	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EPG46_RS16825	COG2205	protein histidine kinase activity
EPG46_RS16830	COG0745	RESPONSE REGULATOR receiver
EPG46_RS16835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EPG46_RS16840	COG2183	response to ionizing radiation
EPG46_RS16845	COG1918	ferrous iron import across plasma membrane
EPG46_RS16850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EPG46_RS16860	COG5464	transposase or invertase
EPG46_RS16870	COG1040	competence protein
EPG46_RS16880	COG2610	gluconate transmembrane transporter activity
EPG46_RS16885	COG1640	4-alpha-glucanotransferase
EPG46_RS16890	COG0058	SHG alpha-glucan phosphorylase activity
EPG46_RS16905	COG1690	Belongs to the RtcB family
EPG46_RS16910	COG4650	regulator
EPG46_RS16915	COG1349	DNA-binding transcription factor activity
EPG46_RS16930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EPG46_RS16940	COG0058	SHG alpha-glucan phosphorylase activity
EPG46_RS16965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPG46_RS16970	COG2095	MarC family integral membrane protein
EPG46_RS16975	COG2610	gluconate transmembrane transporter activity
EPG46_RS16980	COG3265	gluconokinase activity
EPG46_RS16985	COG1609	Transcriptional regulator
EPG46_RS16990	COG1741	Belongs to the pirin family
EPG46_RS16995	COG0673	inositol 2-dehydrogenase activity
EPG46_RS17000	COG1247	-acetyltransferase
EPG46_RS17005	COG3157	Type VI secretion system effector, Hcp
EPG46_RS17025	COG0405	Gamma-glutamyltransferase
EPG46_RS17035	COG0584	glycerophosphoryl diester phosphodiesterase
EPG46_RS17040	COG3842	ATPase activity
EPG46_RS17045	COG0395	ABC-type sugar transport system, permease component
EPG46_RS17050	COG1175	transmembrane transport
EPG46_RS17055	COG1653	transport
EPG46_RS17060	COG0410	ABC transporter
EPG46_RS17065	COG0411	ABC transporter
EPG46_RS17070	COG4177	L-phenylalanine transmembrane transporter activity
EPG46_RS17075	COG0559	Belongs to the binding-protein-dependent transport system permease family
EPG46_RS17080	COG0683	leucine binding
EPG46_RS17085	COG0456	acetyltransferase
EPG46_RS17090	COG0683	leucine binding
EPG46_RS17095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPG46_RS17100	COG2177	Part of the ABC transporter FtsEX involved in
EPG46_RS17105	COG2884	Cell division ATP-binding protein ftsE
EPG46_RS17110	COG0552	protein localization to endoplasmic reticulum
EPG46_RS17115	COG0742	ribosomal rna small subunit methyltransferase
EPG46_RS17120	COG3776	membrane
EPG46_RS17130	COG3714	YhhN family
EPG46_RS17135	COG2217	Heavy metal translocating P-type atpase
EPG46_RS17145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EPG46_RS17155	COG0477	Major facilitator Superfamily
EPG46_RS17160	COG0628	permease
EPG46_RS17165	COG2091	lysine biosynthetic process via aminoadipic acid
EPG46_RS17170	COG0747	negative chemotaxis
EPG46_RS17175	COG0601	transmembrane transport
EPG46_RS17180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPG46_RS17185	COG0444	Belongs to the ABC transporter superfamily
EPG46_RS17190	COG1124	(ABC) transporter
EPG46_RS17210	COG1413	lyase activity
EPG46_RS17215	COG5433	transposase activity
EPG46_RS17220	COG0842	Transport permease protein
EPG46_RS17225	COG0842	Transport permease protein
EPG46_RS17225	COG1129	ABC transporter
EPG46_RS17230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPG46_RS17250	COG2081	HI0933 family
EPG46_RS17255	COG0306	phosphate transporter
EPG46_RS17265	COG0589	response to stress
EPG46_RS17270	COG3104	oligopeptide transport
EPG46_RS17280	COG0339	signal peptide processing
EPG46_RS17285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EPG46_RS17290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPG46_RS17300	COG0640	Transcriptional regulator
EPG46_RS17305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EPG46_RS17310	COG1393	Belongs to the ArsC family
EPG46_RS17320	COG3065	identical protein binding
EPG46_RS17325	COG2197	response regulator
EPG46_RS17330	COG1285	pathogenesis
EPG46_RS17345	COG3247	response to pH
EPG46_RS17350	COG2771	luxR family
EPG46_RS17360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPG46_RS17365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPG46_RS17370	COG2207	Transcriptional regulator
EPG46_RS17375	COG2207	Transcriptional regulator
EPG46_RS17385	COG1858	cytochrome C peroxidase
EPG46_RS17395	COG2197	response regulator
EPG46_RS17400	COG0583	DNA-binding transcription factor activity
EPG46_RS17405	COG1295	ribonuclease BN
EPG46_RS17410	COG0477	Major facilitator Superfamily
EPG46_RS17415	COG2982	Protein involved in outer membrane biogenesis
EPG46_RS17420	COG2200	EAL domain
EPG46_RS17425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS17430	COG0612	Peptidase, M16
EPG46_RS17440	COG2199	diguanylate cyclase activity
EPG46_RS17440	COG2200	EAL domain
EPG46_RS17445	COG3118	belongs to the thioredoxin family
EPG46_RS17445	COG0457	Tetratricopeptide repeat
EPG46_RS17455	COG1215	transferase activity, transferring glycosyl groups
EPG46_RS17460	COG1215	transferase activity, transferring glycosyl groups
EPG46_RS17490	COG2194	sulfuric ester hydrolase activity
EPG46_RS17505	COG0814	amino acid
EPG46_RS17510	COG4608	Belongs to the ABC transporter superfamily
EPG46_RS17515	COG0444	Belongs to the ABC transporter superfamily
EPG46_RS17520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPG46_RS17525	COG0601	transmembrane transport
EPG46_RS17530	COG0747	negative chemotaxis
EPG46_RS17545	COG2194	sulfuric ester hydrolase activity
EPG46_RS17550	COG2223	nitrite transmembrane transporter activity
EPG46_RS17555	COG5571	outer membrane autotransporter
EPG46_RS17560	COG2818	Glycosylase
EPG46_RS17565	COG0456	acetyltransferase
EPG46_RS17570	COG0243	molybdopterin cofactor binding
EPG46_RS17575	COG2885	chlorophyll binding
EPG46_RS17590	COG2944	sequence-specific DNA binding
EPG46_RS17595	COG1278	Cold shock
EPG46_RS17625	COG3274	enterobacterial common antigen metabolic process
EPG46_RS17630	COG4682	membrane
EPG46_RS17635	COG4682	membrane
EPG46_RS17640	COG1070	Carbohydrate kinase
EPG46_RS17650	COG4213	ABC transporter substrate-binding protein
EPG46_RS17655	COG1129	ABC transporter
EPG46_RS17660	COG4214	carbohydrate transport
EPG46_RS17665	COG1609	Transcriptional regulator
EPG46_RS17665	COG2207	Transcriptional regulator
EPG46_RS17670	COG2992	FlgJ-related protein
EPG46_RS17675	COG0366	Alpha amylase catalytic
EPG46_RS17680	COG3977	Valine--pyruvate aminotransferase
EPG46_RS17685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPG46_RS17690	COG1414	Transcriptional regulator
EPG46_RS17700	COG2731	YhcH YjgK YiaL family protein
EPG46_RS17705	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EPG46_RS17710	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EPG46_RS17715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EPG46_RS17720	COG1070	Carbohydrate kinase
EPG46_RS17725	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EPG46_RS17730	COG3623	hexulose-6-phosphate isomerase
EPG46_RS17735	COG0235	Class ii aldolase
EPG46_RS17745	COG3713	MltA-interacting MipA family protein
EPG46_RS17750	COG0583	DNA-binding transcription factor activity
EPG46_RS17755	COG1566	PFAM secretion protein HlyD family protein
EPG46_RS17770	COG1012	belongs to the aldehyde dehydrogenase family
EPG46_RS17775	COG1454	alcohol dehydrogenase
EPG46_RS17780	COG3276	selenocysteine insertion sequence binding
EPG46_RS17790	COG0625	glutathione transferase activity
EPG46_RS17805	COG3209	COG3209 Rhs family protein
EPG46_RS17810	COG1413	lyase activity
EPG46_RS17815	COG3209	COG3209 Rhs family protein
EPG46_RS17820	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EPG46_RS17830	COG1566	PFAM secretion protein HlyD family protein
EPG46_RS17840	COG2213	PTS system mannitol-specific
EPG46_RS17840	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS17850	COG3722	fumarate hydratase activity
EPG46_RS17865	COG1620	l-lactate permease
EPG46_RS17870	COG2186	Transcriptional regulator
EPG46_RS17880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EPG46_RS17885	COG1045	serine acetyltransferase
EPG46_RS17900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EPG46_RS17905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPG46_RS17915	COG4942	peptidase
EPG46_RS17920	COG2861	carbohydrate metabolic process
EPG46_RS17925	COG1216	Glycosyl transferase, family 2
EPG46_RS17935	COG0156	8-amino-7-oxononanoate synthase activity
EPG46_RS17945	COG0859	PFAM glycosyl transferase family 9
EPG46_RS17950	COG0859	PFAM glycosyl transferase family 9
EPG46_RS17970	COG3642	lipopolysaccharide core region biosynthetic process
EPG46_RS17975	COG1442	glycosyl transferase family 8
EPG46_RS17980	COG1442	glycosyl transferase family 8
EPG46_RS17985	COG0438	transferase activity, transferring glycosyl groups
EPG46_RS17990	COG1442	glycosyl transferase family 8
EPG46_RS17995	COG0515	serine threonine protein kinase
EPG46_RS18000	COG0438	transferase activity, transferring glycosyl groups
EPG46_RS18005	COG0859	PFAM glycosyl transferase family 9
EPG46_RS18010	COG1519	Transferase
EPG46_RS18040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EPG46_RS18065	COG1561	YicC-like family, N-terminal region
EPG46_RS18070	COG3645	SOS response
EPG46_RS18075	COG2860	membrane
EPG46_RS18085	COG0194	GDP metabolic process
EPG46_RS18095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPG46_RS18100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPG46_RS18105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EPG46_RS18110	COG0786	glutamate:sodium symporter activity
EPG46_RS18115	COG2233	PERMEase
EPG46_RS18120	COG2982	Protein involved in outer membrane biogenesis
EPG46_RS18125	COG1501	Belongs to the glycosyl hydrolase 31 family
EPG46_RS18130	COG2211	Major facilitator Superfamily
EPG46_RS18145	COG2814	Major facilitator Superfamily
EPG46_RS18150	COG0697	spore germination
EPG46_RS18155	COG1464	Belongs to the NlpA lipoprotein family
EPG46_RS18175	COG2252	PERMEase
EPG46_RS18185	COG2271	Major facilitator Superfamily
EPG46_RS18190	COG2271	Major facilitator Superfamily
EPG46_RS18195	COG3851	Histidine kinase
EPG46_RS18200	COG2197	response regulator
EPG46_RS18205	COG0440	acetolactate synthase activity
EPG46_RS18210	COG0028	Belongs to the TPP enzyme family
EPG46_RS18225	COG2814	Major facilitator Superfamily
EPG46_RS18230	COG0641	radical SAM
EPG46_RS18240	COG2149	membrane
EPG46_RS18250	COG3119	arylsulfatase activity
EPG46_RS18255	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPG46_RS18260	COG2207	Transcriptional regulator
EPG46_RS18275	COG2188	Transcriptional regulator
EPG46_RS18295	COG5645	(Lipo)protein
EPG46_RS18300	COG0823	Involved in the tonB-independent uptake of proteins
EPG46_RS18305	COG0644	oxidoreductase
EPG46_RS18310	COG2271	Major facilitator Superfamily
EPG46_RS18320	COG0800	Aldolase
EPG46_RS18325	COG3734	2-keto-3-deoxy-galactonokinase
EPG46_RS18330	COG2186	Transcriptional regulator
EPG46_RS18340	COG0561	phosphatase activity
EPG46_RS18345	COG3753	Protein conserved in bacteria
EPG46_RS18350	COG0187	DNA topoisomerase II activity
EPG46_RS18360	COG0592	DNA-directed DNA polymerase activity
EPG46_RS18410	COG0814	amino acid
EPG46_RS18425	COG2091	lysine biosynthetic process via aminoadipic acid
EPG46_RS18430	COG0431	NADPH-dependent FMN reductase
EPG46_RS18435	COG2252	PERMEase
EPG46_RS18440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPG46_RS18460	COG3436	PFAM IS66 Orf2 family protein
EPG46_RS18470	COG3196	Protein conserved in bacteria
EPG46_RS18475	COG0363	glucosamine-6-phosphate deaminase activity
EPG46_RS18480	COG2382	esterase
EPG46_RS18490	COG2723	6-phospho-beta-galactosidase activity
EPG46_RS18495	COG2190	(PTS) system
EPG46_RS18495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS18495	COG1263	PTS System
EPG46_RS18500	COG3711	transcriptional antiterminator
EPG46_RS18505	COG0704	Plays a role in the regulation of phosphate uptake
EPG46_RS18510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EPG46_RS18515	COG0581	inorganic phosphate transmembrane transporter activity
EPG46_RS18520	COG0573	inorganic phosphate transmembrane transporter activity
EPG46_RS18525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EPG46_RS18530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EPG46_RS18580	COG3312	ion transport
EPG46_RS18595	COG0716	FMN binding
EPG46_RS18600	COG1522	sequence-specific DNA binding
EPG46_RS18630	COG1129	ABC transporter
EPG46_RS18635	COG1172	Belongs to the binding-protein-dependent transport system permease family
EPG46_RS18640	COG1879	ABC-type sugar transport system periplasmic component
EPG46_RS18645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS18650	COG1609	Transcriptional regulator
EPG46_RS18655	COG0477	Major facilitator Superfamily
EPG46_RS18660	COG2186	Transcriptional regulator
EPG46_RS18700	COG3085	chromosome segregation
EPG46_RS18705	COG0606	chelatase, subunit chli
EPG46_RS18725	COG3978	acetolactate synthase activity
EPG46_RS18730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EPG46_RS18740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EPG46_RS18745	COG0583	DNA-binding transcription factor activity
EPG46_RS18755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EPG46_RS18765	COG0210	DNA helicase
EPG46_RS18780	COG3118	belongs to the thioredoxin family
EPG46_RS18790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EPG46_RS18795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPG46_RS18800	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EPG46_RS18805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EPG46_RS18810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EPG46_RS18815	COG1088	dTDP-glucose 4,6-dehydratase activity
EPG46_RS18820	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EPG46_RS18825	COG0456	acetyltransferase
EPG46_RS18830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EPG46_RS18835	COG2244	polysaccharide biosynthetic process
EPG46_RS18855	COG1113	amino acid transport
EPG46_RS18880	COG0641	radical SAM
EPG46_RS18885	COG3119	arylsulfatase activity
EPG46_RS18890	COG3071	HemY protein
EPG46_RS18895	COG2959	enzyme of heme biosynthesis
EPG46_RS18900	COG1587	Uroporphyrinogen-III synthase
EPG46_RS18910	COG3072	Adenylate cyclase
EPG46_RS18920	COG5567	small periplasmic lipoprotein
EPG46_RS18930	COG3159	Protein conserved in bacteria
EPG46_RS18940	COG1011	Hydrolase
EPG46_RS18945	COG0210	DNA helicase
EPG46_RS18950	COG3698	Phosphodiester glycosidase
EPG46_RS18955	COG0598	Magnesium transport protein CorA
EPG46_RS18970	COG2962	Rard protein
EPG46_RS18975	COG2050	protein possibly involved in aromatic compounds catabolism
EPG46_RS18980	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EPG46_RS18985	COG0514	ATP-dependent DNA helicase (RecQ)
EPG46_RS18990	COG1280	lysine exporter protein (LysE YggA)
EPG46_RS18995	COG1280	lysine exporter protein (LysE YggA)
EPG46_RS19000	COG2267	carboxylic ester hydrolase activity
EPG46_RS19005	COG0561	phosphatase activity
EPG46_RS19010	COG0697	spore germination
EPG46_RS19015	COG0583	DNA-binding transcription factor activity
EPG46_RS19025	COG0412	Dienelactone hydrolase
EPG46_RS19030	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EPG46_RS19035	COG1322	Protein conserved in bacteria
EPG46_RS19045	COG3165	ubiquinone biosynthetic process from chorismate
EPG46_RS19055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPG46_RS19060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPG46_RS19065	COG0805	protein transport
EPG46_RS19070	COG0084	hydrolase, TatD family'
EPG46_RS19075	COG0250	Participates in transcription elongation, termination and antitermination
EPG46_RS19080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EPG46_RS19085	COG0543	2 iron, 2 sulfur cluster binding
EPG46_RS19090	COG0183	Belongs to the thiolase family
EPG46_RS19105	COG1739	Uncharacterized protein family UPF0029
EPG46_RS19110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EPG46_RS19115	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EPG46_RS19145	COG1763	Mo-molybdopterin cofactor biosynthetic process
EPG46_RS19150	COG0746	molybdenum cofactor guanylyltransferase activity
EPG46_RS19155	COG3084	Protein conserved in bacteria
EPG46_RS19160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EPG46_RS19165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EPG46_RS19170	COG5339	Protein conserved in bacteria
EPG46_RS19175	COG0204	Acyl-transferase
EPG46_RS19180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPG46_RS19180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPG46_RS19195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EPG46_RS19205	COG2204	response regulator
EPG46_RS19210	COG3852	Histidine kinase
EPG46_RS19215	COG0174	glutamine synthetase
EPG46_RS19225	COG2188	Transcriptional regulator
EPG46_RS19230	COG1082	Xylose isomerase domain protein TIM barrel
EPG46_RS19235	COG2271	Major facilitator Superfamily
EPG46_RS19240	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EPG46_RS19245	COG2211	Major facilitator Superfamily
EPG46_RS19250	COG2211	Major facilitator Superfamily
EPG46_RS19255	COG1501	Belongs to the glycosyl hydrolase 31 family
EPG46_RS19260	COG2017	converts alpha-aldose to the beta-anomer
EPG46_RS19265	COG2942	2-epimerase
EPG46_RS19270	COG3684	Belongs to the aldolase LacD family
EPG46_RS19275	COG2084	Dehydrogenase
EPG46_RS19280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPG46_RS19285	COG1349	DNA-binding transcription factor activity
EPG46_RS19290	COG1011	Hydrolase
EPG46_RS19305	COG0456	acetyltransferase
EPG46_RS19310	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EPG46_RS19315	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EPG46_RS19325	COG2864	formate dehydrogenase
EPG46_RS19330	COG0437	4 iron, 4 sulfur cluster binding
EPG46_RS19350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS19350	COG3711	transcriptional antiterminator
EPG46_RS19355	COG1363	Peptidase, m42
EPG46_RS19360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS19360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS19365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS19405	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EPG46_RS19415	COG2258	MOSC domain
EPG46_RS19420	COG2205	protein histidine kinase activity
EPG46_RS19425	COG0745	RESPONSE REGULATOR receiver
EPG46_RS19430	COG3678	ATP-independent chaperone mediated protein folding
EPG46_RS19445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EPG46_RS19465	COG3152	Membrane
EPG46_RS19470	COG3691	Protein conserved in bacteria
EPG46_RS19475	COG0589	response to stress
EPG46_RS19480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPG46_RS19485	COG1494	fructose-1,6-bisphosphatase
EPG46_RS19495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EPG46_RS19510	COG1575	Belongs to the MenA family. Type 1 subfamily
EPG46_RS19525	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EPG46_RS19530	COG1609	Transcriptional regulator
EPG46_RS19535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPG46_RS19545	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EPG46_RS19555	COG0626	cystathionine gamma-synthase activity
EPG46_RS19560	COG0527	aspartate kinase activity
EPG46_RS19560	COG0460	homoserine dehydrogenase
EPG46_RS19565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EPG46_RS19575	COG0697	spore germination
EPG46_RS19580	COG3738	Protein conserved in bacteria
EPG46_RS19585	COG0371	Dehydrogenase
EPG46_RS19590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPG46_RS19595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPG46_RS19595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS19595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS19600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS19605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS19610	COG1882	Formate acetyltransferase
EPG46_RS19615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPG46_RS19620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPG46_RS19625	COG2207	Transcriptional regulator
EPG46_RS19630	COG2194	sulfuric ester hydrolase activity
EPG46_RS19645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EPG46_RS19660	COG0583	DNA-binding transcription factor activity
EPG46_RS19670	COG1309	transcriptional regulator
EPG46_RS19685	COG4206	TonB-dependent receptor
EPG46_RS19715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EPG46_RS19720	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EPG46_RS19720	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EPG46_RS19755	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EPG46_RS19760	COG0250	Participates in transcription elongation, termination and antitermination
EPG46_RS19800	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EPG46_RS19810	COG2104	thiamine diphosphate biosynthetic process
EPG46_RS19815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EPG46_RS19850	COG3068	Protein conserved in bacteria
EPG46_RS19865	COG3678	ATP-independent chaperone mediated protein folding
EPG46_RS19870	COG4191	Histidine kinase
EPG46_RS19875	COG2204	response regulator
EPG46_RS19880	COG0151	Belongs to the GarS family
EPG46_RS19915	COG0456	acetyltransferase
EPG46_RS19925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EPG46_RS19930	COG2224	Isocitrate lyase
EPG46_RS19945	COG1414	Transcriptional regulator
EPG46_RS19950	COG1410	methionine synthase
EPG46_RS19950	COG0646	methionine synthase
EPG46_RS19955	COG1283	sodium-dependent phosphate transmembrane transporter activity
EPG46_RS19965	COG1187	pseudouridine synthase activity
EPG46_RS19975	COG0527	aspartate kinase activity
EPG46_RS20000	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPG46_RS20020	COG0477	Major facilitator Superfamily
EPG46_RS20020	COG2814	Major facilitator Superfamily
EPG46_RS20025	COG3833	ABC-type maltose transport systems, permease component
EPG46_RS20030	COG1175	transmembrane transport
EPG46_RS20035	COG2182	Extracellular solute-binding protein
EPG46_RS20040	COG3842	ATPase activity
EPG46_RS20075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EPG46_RS20085	COG0534	Mate efflux family protein
EPG46_RS20090	COG3237	CsbD-like
EPG46_RS20095	COG0735	belongs to the Fur family
EPG46_RS20110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPG46_RS20120	COG0604	alcohol dehydrogenase
EPG46_RS20125	COG0305	Participates in initiation and elongation during chromosome replication
EPG46_RS20130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPG46_RS20135	COG1448	Aminotransferase
EPG46_RS20145	COG3700	Belongs to the class B bacterial acid phosphatase family
EPG46_RS20150	COG0432	Pfam Uncharacterised protein family UPF0047
EPG46_RS20155	COG2315	Protein conserved in bacteria
EPG46_RS20160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EPG46_RS20165	COG0629	single-stranded DNA binding
EPG46_RS20175	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EPG46_RS20180	COG2207	Transcriptional regulator
EPG46_RS20185	COG0789	Transcriptional regulator
EPG46_RS20190	COG2252	PERMEase
EPG46_RS20195	COG0025	NhaP-type Na H and K H
EPG46_RS20200	COG1357	PFAM Pentapeptide repeats (8 copies)
EPG46_RS20210	COG3162	membrane
EPG46_RS20215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EPG46_RS20225	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EPG46_RS20230	COG0437	4 iron, 4 sulfur cluster binding
EPG46_RS20235	COG3301	Polysulphide reductase, NrfD
EPG46_RS20240	COG1138	Cytochrome C-type biogenesis protein
EPG46_RS20245	COG3088	subunit of a heme lyase
EPG46_RS20250	COG4235	cytochrome complex assembly
EPG46_RS20255	COG1301	dicarboxylic acid transport
EPG46_RS20260	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EPG46_RS20270	COG1538	Outer membrane efflux protein
EPG46_RS20275	COG1289	transmembrane transporter activity
EPG46_RS20280	COG1566	PFAM secretion protein HlyD family protein
EPG46_RS20290	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EPG46_RS20295	COG1940	carbohydrate kinase activity
EPG46_RS20300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EPG46_RS20305	COG1172	Belongs to the binding-protein-dependent transport system permease family
EPG46_RS20315	COG1879	ABC-type sugar transport system periplasmic component
EPG46_RS20320	COG1737	Transcriptional regulator
EPG46_RS20325	COG0698	ribose 5-phosphate isomerase
EPG46_RS20335	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EPG46_RS20340	COG0456	acetyltransferase
EPG46_RS20345	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EPG46_RS20350	COG3454	Phosphonate metabolism
EPG46_RS20355	COG4778	phosphonate C-P lyase system protein PhnL
EPG46_RS20360	COG4107	phosphonate C-P lyase system protein PhnK
EPG46_RS20365	COG3627	carbon phosphorus lyase activity
EPG46_RS20370	COG3626	phosphonate metabolism
EPG46_RS20375	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EPG46_RS20380	COG3624	Phosphonate C-P lyase system protein PhnG
EPG46_RS20385	COG2188	Transcriptional regulator
EPG46_RS20395	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EPG46_RS20400	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EPG46_RS20405	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EPG46_RS20410	COG2824	Alkylphosphonate utilization operon protein PhnA
EPG46_RS20415	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EPG46_RS20425	COG0477	Major facilitator Superfamily
EPG46_RS20435	COG0642	Histidine kinase
EPG46_RS20440	COG0745	RESPONSE REGULATOR receiver
EPG46_RS20445	COG2194	sulfuric ester hydrolase activity
EPG46_RS20450	COG0531	amino acid
EPG46_RS20455	COG2207	Transcriptional regulator
EPG46_RS20460	COG1982	Orn Lys Arg decarboxylase major
EPG46_RS20465	COG2169	Transcriptional regulator
EPG46_RS20470	COG1486	melibiose metabolic process
EPG46_RS20475	COG2211	Major facilitator Superfamily
EPG46_RS20480	COG3647	Membrane
EPG46_RS20485	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EPG46_RS20485	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EPG46_RS20490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EPG46_RS20495	COG4565	transcriptional regulatory protein
EPG46_RS20500	COG3290	protein histidine kinase activity
EPG46_RS20505	COG3592	Divergent 4Fe-4S mono-cluster
EPG46_RS20510	COG2388	GCN5-related N-acetyl-transferase
EPG46_RS20525	COG1309	transcriptional regulator
EPG46_RS20530	COG4232	protein-disulfide reductase activity
EPG46_RS20540	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EPG46_RS20545	COG1027	Aspartate ammonia-lyase
EPG46_RS20550	COG3030	protein affecting phage T7 exclusion by the F plasmid
EPG46_RS20555	COG0531	amino acid
EPG46_RS20580	COG1509	lysine 2,3-aminomutase activity
EPG46_RS20590	COG5510	response to toxic substance
EPG46_RS20595	COG5510	response to toxic substance
EPG46_RS20600	COG2076	Multidrug Resistance protein
EPG46_RS20605	COG3040	lipid binding
EPG46_RS20610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EPG46_RS20625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EPG46_RS20630	COG1053	succinate dehydrogenase
EPG46_RS20640	COG0531	amino acid
EPG46_RS20655	COG1511	domain protein
EPG46_RS20655	COG3264	Mechanosensitive ion channel
EPG46_RS20695	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EPG46_RS20700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EPG46_RS20700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPG46_RS20705	COG0802	atpase or kinase
EPG46_RS20710	COG0860	N-Acetylmuramoyl-L-alanine amidase
EPG46_RS20730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPG46_RS20735	COG0330	HflC and HflK could
EPG46_RS20740	COG0330	HflC and HflK could
EPG46_RS20745	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EPG46_RS20760	COG0557	exoribonuclease II activity
EPG46_RS20765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPG46_RS20770	COG1414	Transcriptional regulator
EPG46_RS20775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPG46_RS20780	COG2271	Major facilitator Superfamily
EPG46_RS20785	COG2721	sulfolactate sulfo-lyase activity
EPG46_RS20805	COG3766	membrane
EPG46_RS20810	COG5463	Belongs to the UPF0441 family
EPG46_RS20815	COG0754	glutathionylspermidine amidase activity
EPG46_RS20820	COG1960	acyl-CoA dehydrogenase activity
EPG46_RS20830	COG3650	response to hydrogen peroxide
EPG46_RS20835	COG1073	alpha beta
EPG46_RS20855	COG3414	Phosphotransferase system galactitol-specific IIB component
EPG46_RS20860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS20875	COG0235	Class ii aldolase
EPG46_RS20880	COG3477	response to acidic pH
EPG46_RS20900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPG46_RS20920	COG0675	Transposase, IS605 OrfB family
EPG46_RS20930	COG3061	Opacity-associated protein A
EPG46_RS20935	COG0545	Peptidyl-prolyl cis-trans isomerase
EPG46_RS20940	COG1113	amino acid transport
EPG46_RS20950	COG0697	spore germination
EPG46_RS20955	COG0702	epimerase
EPG46_RS20960	COG1733	regulation of RNA biosynthetic process
EPG46_RS20965	COG0737	Belongs to the 5'-nucleotidase family
EPG46_RS20970	COG1218	3'(2'),5'-bisphosphate nucleotidase
EPG46_RS21000	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EPG46_RS21010	COG1253	flavin adenine dinucleotide binding
EPG46_RS21020	COG0729	surface antigen
EPG46_RS21025	COG2911	Protein conserved in bacteria
EPG46_RS21030	COG2105	PFAM AIG2 family protein
EPG46_RS21035	COG2336	PFAM SpoVT AbrB
EPG46_RS21040	COG2337	Toxic component of a toxin-antitoxin (TA) module
EPG46_RS21045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EPG46_RS21050	COG1879	ABC-type sugar transport system periplasmic component
EPG46_RS21055	COG1129	ABC transporter
EPG46_RS21060	COG1172	Belongs to the binding-protein-dependent transport system permease family
EPG46_RS21065	COG1172	Belongs to the binding-protein-dependent transport system permease family
EPG46_RS21075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EPG46_RS21085	COG0312	modulator of DNA gyrase
EPG46_RS21090	COG3783	Cytochrome b(562)
EPG46_RS21095	COG0602	queuosine metabolic process
EPG46_RS21100	COG1328	CTP reductase activity
EPG46_RS21105	COG0366	Alpha amylase catalytic
EPG46_RS21110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPG46_RS21110	COG1263	PTS System
EPG46_RS21115	COG1609	Transcriptional regulator
EPG46_RS21125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EPG46_RS21130	COG0251	oxidation-reduction process
EPG46_RS21150	COG0251	oxidation-reduction process
EPG46_RS21155	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS21160	COG1309	transcriptional regulator
EPG46_RS21165	COG2731	YhcH YjgK YiaL family protein
EPG46_RS21180	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EPG46_RS21185	COG0456	acetyltransferase
EPG46_RS21195	COG0525	valine-tRNA ligase activity
EPG46_RS21200	COG2927	DNA polymerase III (CHI subunit)
EPG46_RS21210	COG0795	lipopolysaccharide-transporting ATPase activity
EPG46_RS21215	COG0795	lipopolysaccharide-transporting ATPase activity
EPG46_RS21220	COG0433	COG0433 Predicted ATPase
EPG46_RS21225	COG1609	Transcriptional regulator
EPG46_RS21230	COG2610	gluconate transmembrane transporter activity
EPG46_RS21235	COG1028	Short-chain dehydrogenase reductase Sdr
EPG46_RS21240	COG1063	alcohol dehydrogenase
EPG46_RS21245	COG3265	gluconokinase activity
EPG46_RS21250	COG1064	alcohol dehydrogenase
EPG46_RS21280	COG3385	transposase activity
EPG46_RS21285	COG2814	Major facilitator Superfamily
EPG46_RS21290	COG0673	inositol 2-dehydrogenase activity
EPG46_RS21315	COG2085	NADP oxidoreductase coenzyme F420-dependent
EPG46_RS21320	COG1120	ATPase activity
EPG46_RS21325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPG46_RS21330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPG46_RS21335	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EPG46_RS21340	COG4772	TonB-dependent receptor
EPG46_RS21345	COG3712	iron ion homeostasis
EPG46_RS21350	COG1595	DNA-templated transcription, initiation
EPG46_RS21390	COG3436	PFAM IS66 Orf2 family protein
EPG46_RS21430	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
EPG46_RS21435	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EPG46_RS21440	COG0582	viral genome integration into host DNA
EPG46_RS21445	COG4974	Belongs to the 'phage' integrase family
EPG46_RS21455	COG3539	Fimbrial protein
EPG46_RS21460	COG3121	Chaperone
EPG46_RS21465	COG3188	usher protein
EPG46_RS21470	COG3539	Fimbrial protein
EPG46_RS21475	COG3539	Fimbrial protein
EPG46_RS21480	COG3539	Fimbrial protein
EPG46_RS21485	COG2610	gluconate transmembrane transporter activity
EPG46_RS21495	COG0246	Mannitol dehydrogenase
EPG46_RS21500	COG2186	Transcriptional regulator
EPG46_RS21520	COG0583	DNA-binding transcription factor activity
EPG46_RS21525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EPG46_RS21530	COG0700	Nucleoside recognition
EPG46_RS21535	COG3366	ferrous iron transmembrane transporter activity
EPG46_RS21545	COG0477	Major facilitator Superfamily
EPG46_RS21560	COG1924	4 iron, 4 sulfur cluster binding
EPG46_RS21565	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
EPG46_RS21570	COG2733	membrane
EPG46_RS21575	COG2814	Major facilitator Superfamily
EPG46_RS21600	COG0523	cobalamin synthesis protein
EPG46_RS21605	COG2879	small protein
EPG46_RS21610	COG1966	Carbon starvation protein
EPG46_RS21615	COG0840	transmembrane signaling receptor activity
EPG46_RS21620	COG2271	Major facilitator Superfamily
EPG46_RS21625	COG1802	Transcriptional regulator
EPG46_RS21635	COG1063	alcohol dehydrogenase
EPG46_RS21650	COG1484	DNA-dependent DNA replication
EPG46_RS21665	COG2966	Psort location CytoplasmicMembrane, score
EPG46_RS21670	COG2197	response regulator
EPG46_RS21675	COG2197	response regulator
EPG46_RS21680	COG4114	ferric iron reductase
EPG46_RS21710	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EPG46_RS21715	COG0456	acetyltransferase
EPG46_RS21720	COG1011	Hydrolase
EPG46_RS21745	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EPG46_RS21750	COG5532	Uncharacterized conserved protein (DUF2303)
EPG46_RS21760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPG46_RS21765	COG4197	protein conserved in bacteria, prophage-related
EPG46_RS21785	COG1846	Transcriptional regulator
EPG46_RS21800	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EPG46_RS21810	COG1403	HNH endonuclease
EPG46_RS21815	COG0484	heat shock protein binding
EPG46_RS21840	COG3772	lysozyme
EPG46_RS21875	COG0740	serine-type endopeptidase activity
EPG46_RS21950	COG5301	cellulose 1,4-beta-cellobiosidase activity
EPG46_RS21995	COG2823	Periplasmic or secreted lipoprotein
EPG46_RS22005	COG4667	esterase of the alpha-beta hydrolase superfamily
EPG46_RS22010	COG0084	hydrolase, TatD family'
EPG46_RS22015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPG46_RS22020	COG1328	CTP reductase activity
EPG46_RS22045	COG3550	peptidyl-serine autophosphorylation
EPG46_RS22055	COG3726	membrane protein affecting hemolysin expression
EPG46_RS22060	COG0560	Phosphoserine phosphatase
EPG46_RS22065	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPG46_RS22070	COG3172	ATPase kinase involved in NAD metabolism
EPG46_RS22070	COG1056	cytidyltransferase-related domain
EPG46_RS22075	COG0488	(ABC) transporter
EPG46_RS22080	COG0741	lytic transglycosylase activity
EPG46_RS22100	COG2207	Transcriptional regulator
EPG46_RS22100	COG3708	Transcriptional regulator
EPG46_RS22105	COG3045	CreA protein
EPG46_RS22110	COG0745	RESPONSE REGULATOR receiver
EPG46_RS22115	COG2205	protein histidine kinase activity
EPG46_RS22120	COG4452	Inner membrane protein CreD
EPG46_RS22125	COG0745	RESPONSE REGULATOR receiver
EPG46_RS22135	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EPG46_RS22145	COG0527	aspartate kinase activity
EPG46_RS22145	COG0460	homoserine dehydrogenase
EPG46_RS22155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EPG46_RS22170	COG1115	amino acid carrier protein
EPG46_RS22180	COG0521	Mo-molybdopterin cofactor biosynthetic process
EPG46_RS22185	COG1584	GPR1 FUN34 yaaH family protein
EPG46_RS22190	COG4735	regulation of single-species biofilm formation
EPG46_RS22220	COG0583	DNA-binding transcription factor activity
EPG46_RS22230	COG3188	usher protein
EPG46_RS22235	COG3121	Chaperone
EPG46_RS22260	COG0196	riboflavin kinase activity
EPG46_RS22275	COG1047	Peptidyl-prolyl cis-trans
EPG46_RS22295	COG0505	Belongs to the CarA family
EPG46_RS22300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EPG46_RS22350	COG0644	oxidoreductase
EPG46_RS22355	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EPG46_RS22360	COG2271	Major facilitator Superfamily
EPG46_RS22375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPG46_RS22400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EPG46_RS22405	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EPG46_RS22410	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EPG46_RS22430	COG0564	pseudouridine synthase activity
EPG46_RS22440	COG0417	DNA replication proofreading
EPG46_RS22445	COG0235	Class ii aldolase
EPG46_RS22450	COG2160	L-arabinose isomerase activity
EPG46_RS22455	COG1069	ribulokinase activity
EPG46_RS22460	COG4977	sequence-specific DNA binding
EPG46_RS22465	COG0586	Pfam SNARE associated Golgi protein
EPG46_RS22470	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EPG46_RS22475	COG1178	ABC-type Fe3 transport system permease component
EPG46_RS22480	COG4143	(ABC) transporter
EPG46_RS22485	COG4533	DNA binding
EPG46_RS22495	COG2814	Major facilitator Superfamily
EPG46_RS22510	COG0473	3-isopropylmalate dehydrogenase activity
EPG46_RS22525	COG0583	DNA-binding transcription factor activity
EPG46_RS22535	COG0028	Belongs to the TPP enzyme family
EPG46_RS22540	COG0440	acetolactate synthase activity
EPG46_RS22550	COG1609	Transcriptional regulator
EPG46_RS22555	COG2001	Belongs to the MraZ family
EPG46_RS22565	COG3116	cell division
EPG46_RS22570	COG0768	penicillin binding
EPG46_RS22575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPG46_RS22580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EPG46_RS22595	COG0772	Belongs to the SEDS family
EPG46_RS22610	COG1181	Belongs to the D-alanine--D-alanine ligase family
EPG46_RS22615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EPG46_RS22620	COG0849	cell division
EPG46_RS22625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPG46_RS22645	COG0494	nUDIX hydrolase
EPG46_RS22660	COG0237	dephospho-CoA kinase activity
EPG46_RS22675	COG1459	type II secretion system
EPG46_RS22680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EPG46_RS22685	COG4969	Belongs to the N-Me-Phe pilin family
EPG46_RS22690	COG0157	Belongs to the NadC ModD family
EPG46_RS22695	COG3023	N-Acetylmuramoyl-L-alanine amidase
EPG46_RS22700	COG3725	Membrane protein required for beta-lactamase induction
EPG46_RS22705	COG1113	amino acid transport
EPG46_RS22710	COG2186	Transcriptional regulator
EPG46_RS22715	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EPG46_RS22720	COG0508	dehydrogenase complex catalyzes the overall conversion of
EPG46_RS22725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPG46_RS22730	COG3064	Membrane
EPG46_RS22735	COG1049	propionate catabolic process, 2-methylcitrate cycle
EPG46_RS22760	COG2132	Multicopper oxidase
EPG46_RS22765	COG4993	Dehydrogenase
EPG46_RS22770	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EPG46_RS22775	COG0288	reversible hydration of carbon dioxide
EPG46_RS22780	COG1131	(ABC) transporter
EPG46_RS22785	COG0842	Transport permease protein
EPG46_RS22790	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPG46_RS22795	COG0726	polysaccharide deacetylase
EPG46_RS22805	COG5464	transposase or invertase
EPG46_RS22820	COG3539	Fimbrial protein
EPG46_RS22825	COG3539	Fimbrial protein
EPG46_RS22830	COG3539	Fimbrial protein
EPG46_RS22835	COG3539	Fimbrial protein
EPG46_RS22840	COG3188	usher protein
EPG46_RS22845	COG3121	Chaperone
EPG46_RS22850	COG3539	Fimbrial protein
EPG46_RS22855	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EPG46_RS22860	COG0617	tRNA 3'-terminal CCA addition
EPG46_RS22870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EPG46_RS22880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EPG46_RS22885	COG1643	Atp-dependent helicase
EPG46_RS22890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EPG46_RS22895	COG4774	siderophore transport
EPG46_RS22900	COG1120	ATPase activity
EPG46_RS22905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EPG46_RS22910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPG46_RS22935	COG2860	membrane
EPG46_RS22940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EPG46_RS22955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPG46_RS22960	COG3835	regulator
EPG46_RS22970	COG1408	metallophosphoesterase
EPG46_RS22985	COG0024	Methionine aminopeptidase
EPG46_RS23010	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EPG46_RS23015	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPG46_RS23020	COG0575	Belongs to the CDS family
EPG46_RS23025	COG0750	zinc metalloprotease
EPG46_RS23035	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EPG46_RS23040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EPG46_RS23065	COG0587	DNA-directed DNA polymerase activity
EPG46_RS23080	COG0346	lactoylglutathione lyase activity
EPG46_RS23085	COG0037	tRNA processing
EPG46_RS23090	COG4568	rho-dependent transcription termination
EPG46_RS23100	COG4681	YaeQ
EPG46_RS23105	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPG46_RS23110	COG3015	lipoprotein NlpE involved in copper resistance
EPG46_RS23115	COG0791	NLP P60 protein
EPG46_RS23125	COG1720	tRNA m6t6A37 methyltransferase activity
EPG46_RS23135	COG1464	Belongs to the NlpA lipoprotein family
EPG46_RS23140	COG2011	ABC-type metal ion transport system permease component
EPG46_RS23145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPG46_RS23150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EPG46_RS23245	COG3344	reverse transcriptase
EPG46_RS23310	COG1196	nuclear chromosome segregation
EPG46_RS23375	COG0673	inositol 2-dehydrogenase activity
EPG46_RS23450	COG3173	Aminoglycoside phosphotransferase
EPG46_RS23480	COG0459	protein refolding
EPG46_RS23810	COG3436	PFAM IS66 Orf2 family protein
EPG46_RS24080	COG0640	Transcriptional regulator
EPG46_RS24125	COG3039	Transposase
EPG46_RS24225	COG1196	nuclear chromosome segregation
EPG46_RS24380	COG3077	Addiction module antitoxin, RelB DinJ family
EPG46_RS24385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EPG46_RS24475	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EPG46_RS24500	COG5301	cellulose 1,4-beta-cellobiosidase activity
EPG46_RS24515	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EPG46_RS24525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EPG46_RS24560	COG0675	Transposase, IS605 OrfB family
EPG46_RS24585	COG0629	single-stranded DNA binding
EPG46_RS24695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPG46_RS24855	COG0305	Participates in initiation and elongation during chromosome replication
EPG46_RS24880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EPG46_RS25030	COG0741	lytic transglycosylase activity