locus-tag	class	description
INR48_RS00030	COG4695	Portal protein
INR48_RS00120	COG5301	cellulose 1,4-beta-cellobiosidase activity
INR48_RS00185	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
INR48_RS00205	COG3152	Membrane
INR48_RS00210	COG3691	Protein conserved in bacteria
INR48_RS00215	COG0589	response to stress
INR48_RS00225	COG1494	fructose-1,6-bisphosphatase
INR48_RS00235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
INR48_RS00260	COG1575	Belongs to the MenA family. Type 1 subfamily
INR48_RS00275	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
INR48_RS00280	COG1609	Transcriptional regulator
INR48_RS00285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
INR48_RS00295	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
INR48_RS00305	COG0626	cystathionine gamma-synthase activity
INR48_RS00310	COG0527	aspartate kinase activity
INR48_RS00310	COG0460	homoserine dehydrogenase
INR48_RS00320	COG0737	Belongs to the 5'-nucleotidase family
INR48_RS00325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
INR48_RS00335	COG0697	spore germination
INR48_RS00340	COG3738	Protein conserved in bacteria
INR48_RS00345	COG0371	Dehydrogenase
INR48_RS00350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
INR48_RS00355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS00355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS00355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
INR48_RS00360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INR48_RS00365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INR48_RS00370	COG1882	Formate acetyltransferase
INR48_RS00375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INR48_RS00380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INR48_RS00385	COG2207	Transcriptional regulator
INR48_RS00390	COG2194	sulfuric ester hydrolase activity
INR48_RS00405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
INR48_RS00420	COG0583	DNA-binding transcription factor activity
INR48_RS00430	COG1309	transcriptional regulator
INR48_RS00445	COG4206	TonB-dependent receptor
INR48_RS00480	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
INR48_RS00480	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
INR48_RS00515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
INR48_RS00520	COG0250	Participates in transcription elongation, termination and antitermination
INR48_RS00560	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
INR48_RS00570	COG2104	thiamine diphosphate biosynthetic process
INR48_RS00575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
INR48_RS00610	COG3068	Protein conserved in bacteria
INR48_RS00625	COG3678	ATP-independent chaperone mediated protein folding
INR48_RS00630	COG4191	Histidine kinase
INR48_RS00635	COG2204	response regulator
INR48_RS00640	COG0151	Belongs to the GarS family
INR48_RS00670	COG0456	acetyltransferase
INR48_RS00680	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
INR48_RS00685	COG2224	Isocitrate lyase
INR48_RS00700	COG1414	Transcriptional regulator
INR48_RS00705	COG1410	methionine synthase
INR48_RS00705	COG0646	methionine synthase
INR48_RS00710	COG1283	sodium-dependent phosphate transmembrane transporter activity
INR48_RS00755	COG1187	pseudouridine synthase activity
INR48_RS00765	COG0527	aspartate kinase activity
INR48_RS00790	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
INR48_RS00805	COG3833	ABC-type maltose transport systems, permease component
INR48_RS00810	COG1175	transmembrane transport
INR48_RS00815	COG2182	Extracellular solute-binding protein
INR48_RS00820	COG3842	ATPase activity
INR48_RS00835	COG1357	PFAM Pentapeptide repeats (8 copies)
INR48_RS00855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
INR48_RS00865	COG0534	Mate efflux family protein
INR48_RS00870	COG3237	CsbD-like
INR48_RS00875	COG0735	belongs to the Fur family
INR48_RS00885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INR48_RS00895	COG0604	alcohol dehydrogenase
INR48_RS00900	COG0305	Participates in initiation and elongation during chromosome replication
INR48_RS00905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
INR48_RS00910	COG1448	Aminotransferase
INR48_RS00920	COG3700	Belongs to the class B bacterial acid phosphatase family
INR48_RS00925	COG0432	Pfam Uncharacterised protein family UPF0047
INR48_RS00930	COG2315	Protein conserved in bacteria
INR48_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
INR48_RS00940	COG0629	single-stranded DNA binding
INR48_RS00950	COG4943	cyclic-guanylate-specific phosphodiesterase activity
INR48_RS00955	COG2207	Transcriptional regulator
INR48_RS00960	COG0789	Transcriptional regulator
INR48_RS00965	COG2252	PERMEase
INR48_RS00970	COG0025	NhaP-type Na H and K H
INR48_RS00975	COG1357	PFAM Pentapeptide repeats (8 copies)
INR48_RS00985	COG3162	membrane
INR48_RS00990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
INR48_RS01000	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
INR48_RS01005	COG0437	4 iron, 4 sulfur cluster binding
INR48_RS01010	COG3301	Polysulphide reductase, NrfD
INR48_RS01015	COG1138	Cytochrome C-type biogenesis protein
INR48_RS01025	COG4235	cytochrome complex assembly
INR48_RS01030	COG1301	dicarboxylic acid transport
INR48_RS01035	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
INR48_RS01050	COG1289	transmembrane transporter activity
INR48_RS01055	COG1566	PFAM secretion protein HlyD family protein
INR48_RS01065	COG2015	COG2015, Alkyl sulfatase and related hydrolases
INR48_RS01070	COG0698	ribose 5-phosphate isomerase
INR48_RS01080	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
INR48_RS01085	COG0456	acetyltransferase
INR48_RS01095	COG3454	Phosphonate metabolism
INR48_RS01100	COG4778	phosphonate C-P lyase system protein PhnL
INR48_RS01105	COG4107	phosphonate C-P lyase system protein PhnK
INR48_RS01110	COG3627	carbon phosphorus lyase activity
INR48_RS01115	COG3626	phosphonate metabolism
INR48_RS01120	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
INR48_RS01125	COG3624	Phosphonate C-P lyase system protein PhnG
INR48_RS01130	COG2188	Transcriptional regulator
INR48_RS01135	COG3639	organic phosphonate transmembrane transporter activity
INR48_RS01140	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
INR48_RS01150	COG2764	glyoxalase bleomycin resistance protein dioxygenase
INR48_RS01155	COG2824	Alkylphosphonate utilization operon protein PhnA
INR48_RS01160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
INR48_RS01170	COG0477	Major facilitator Superfamily
INR48_RS01180	COG0642	Histidine kinase
INR48_RS01185	COG0745	RESPONSE REGULATOR receiver
INR48_RS01190	COG2194	sulfuric ester hydrolase activity
INR48_RS01195	COG0531	amino acid
INR48_RS01200	COG2207	Transcriptional regulator
INR48_RS01205	COG1982	Orn Lys Arg decarboxylase major
INR48_RS01210	COG2169	Transcriptional regulator
INR48_RS01215	COG1486	melibiose metabolic process
INR48_RS01220	COG2211	Major facilitator Superfamily
INR48_RS01225	COG3647	Membrane
INR48_RS01230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
INR48_RS01230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
INR48_RS01235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
INR48_RS01240	COG4565	transcriptional regulatory protein
INR48_RS01245	COG3290	protein histidine kinase activity
INR48_RS01250	COG3592	Divergent 4Fe-4S mono-cluster
INR48_RS01255	COG2388	GCN5-related N-acetyl-transferase
INR48_RS01270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
INR48_RS01275	COG3104	oligopeptide transport
INR48_RS01280	COG1982	Orn Lys Arg decarboxylase major
INR48_RS01285	COG0531	amino acid
INR48_RS01290	COG3710	Transcriptional regulator
INR48_RS01300	COG1309	transcriptional regulator
INR48_RS01305	COG4232	protein-disulfide reductase activity
INR48_RS01315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
INR48_RS01320	COG1027	Aspartate ammonia-lyase
INR48_RS01325	COG3030	protein affecting phage T7 exclusion by the F plasmid
INR48_RS01330	COG0531	amino acid
INR48_RS01355	COG1509	lysine 2,3-aminomutase activity
INR48_RS01365	COG5510	response to toxic substance
INR48_RS01370	COG5510	response to toxic substance
INR48_RS01375	COG2076	Multidrug Resistance protein
INR48_RS01380	COG3040	lipid binding
INR48_RS01385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
INR48_RS01400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
INR48_RS01405	COG1053	succinate dehydrogenase
INR48_RS01415	COG0531	amino acid
INR48_RS01420	COG1511	domain protein
INR48_RS01420	COG3264	Mechanosensitive ion channel
INR48_RS01460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
INR48_RS01465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
INR48_RS01465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
INR48_RS01470	COG0802	atpase or kinase
INR48_RS01475	COG0860	N-Acetylmuramoyl-L-alanine amidase
INR48_RS01495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
INR48_RS01500	COG0330	HflC and HflK could
INR48_RS01505	COG0330	HflC and HflK could
INR48_RS01510	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
INR48_RS01525	COG0557	exoribonuclease II activity
INR48_RS01530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INR48_RS01535	COG3789	protein conserved in bacteria
INR48_RS01540	COG1842	Phage shock protein A
INR48_RS01550	COG3766	membrane
INR48_RS01555	COG5463	Belongs to the UPF0441 family
INR48_RS01560	COG0754	glutathionylspermidine amidase activity
INR48_RS01565	COG1960	acyl-CoA dehydrogenase activity
INR48_RS01575	COG3650	response to hydrogen peroxide
INR48_RS01580	COG1073	alpha beta
INR48_RS01595	COG3037	sugar-specific permease SgaT UlaA
INR48_RS01600	COG3414	Phosphotransferase system galactitol-specific IIB component
INR48_RS01605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS01640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
INR48_RS01665	COG0675	Transposase, IS605 OrfB family
INR48_RS01675	COG3061	Opacity-associated protein A
INR48_RS01680	COG0545	Peptidyl-prolyl cis-trans isomerase
INR48_RS01685	COG1113	amino acid transport
INR48_RS01705	COG0697	spore germination
INR48_RS01710	COG0702	epimerase
INR48_RS01715	COG1733	regulation of RNA biosynthetic process
INR48_RS01720	COG0737	Belongs to the 5'-nucleotidase family
INR48_RS01725	COG1218	3'(2'),5'-bisphosphate nucleotidase
INR48_RS01735	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
INR48_RS01745	COG1253	flavin adenine dinucleotide binding
INR48_RS01755	COG0729	surface antigen
INR48_RS01760	COG2911	Protein conserved in bacteria
INR48_RS01765	COG2105	PFAM AIG2 family protein
INR48_RS01770	COG2336	PFAM SpoVT AbrB
INR48_RS01775	COG2337	Toxic component of a toxin-antitoxin (TA) module
INR48_RS01780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
INR48_RS01785	COG1879	ABC-type sugar transport system periplasmic component
INR48_RS01790	COG1129	ABC transporter
INR48_RS01795	COG1172	Belongs to the binding-protein-dependent transport system permease family
INR48_RS01800	COG1172	Belongs to the binding-protein-dependent transport system permease family
INR48_RS01810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
INR48_RS01820	COG0312	modulator of DNA gyrase
INR48_RS01825	COG3783	Cytochrome b(562)
INR48_RS01830	COG3077	Addiction module antitoxin, RelB DinJ family
INR48_RS01835	COG2026	Addiction module toxin, RelE StbE family
INR48_RS01840	COG0602	queuosine metabolic process
INR48_RS01845	COG1328	CTP reductase activity
INR48_RS01850	COG0366	Alpha amylase catalytic
INR48_RS01855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS01855	COG1263	PTS System
INR48_RS01860	COG1609	Transcriptional regulator
INR48_RS01870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
INR48_RS01875	COG0251	oxidation-reduction process
INR48_RS01895	COG0251	oxidation-reduction process
INR48_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS01905	COG1309	transcriptional regulator
INR48_RS01910	COG2731	YhcH YjgK YiaL family protein
INR48_RS01925	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
INR48_RS01930	COG0456	acetyltransferase
INR48_RS01935	COG4269	membrane
INR48_RS01940	COG0525	valine-tRNA ligase activity
INR48_RS01945	COG2927	DNA polymerase III (CHI subunit)
INR48_RS01955	COG0795	lipopolysaccharide-transporting ATPase activity
INR48_RS01960	COG0795	lipopolysaccharide-transporting ATPase activity
INR48_RS01965	COG0433	COG0433 Predicted ATPase
INR48_RS01970	COG1064	alcohol dehydrogenase
INR48_RS01980	COG0582	viral genome integration into host DNA
INR48_RS02060	COG0328	RNA-DNA hybrid ribonuclease activity
INR48_RS02065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INR48_RS02065	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
INR48_RS02080	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
INR48_RS02095	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
INR48_RS02120	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
INR48_RS02125	COG0582	viral genome integration into host DNA
INR48_RS02130	COG4974	Belongs to the 'phage' integrase family
INR48_RS02135	COG3539	Fimbrial protein
INR48_RS02140	COG3539	Fimbrial protein
INR48_RS02145	COG3121	Chaperone
INR48_RS02150	COG3188	usher protein
INR48_RS02155	COG3539	Fimbrial protein
INR48_RS02160	COG3539	Fimbrial protein
INR48_RS02165	COG3539	Fimbrial protein
INR48_RS02170	COG2610	gluconate transmembrane transporter activity
INR48_RS02180	COG0246	Mannitol dehydrogenase
INR48_RS02185	COG2186	Transcriptional regulator
INR48_RS02205	COG0583	DNA-binding transcription factor activity
INR48_RS02210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
INR48_RS02215	COG0700	Nucleoside recognition
INR48_RS02220	COG3366	ferrous iron transmembrane transporter activity
INR48_RS02230	COG1388	LysM domain
INR48_RS02230	COG1470	cell adhesion involved in biofilm formation
INR48_RS02235	COG0477	Major facilitator Superfamily
INR48_RS02240	COG3204	pilus organization
INR48_RS02255	COG1924	4 iron, 4 sulfur cluster binding
INR48_RS02260	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
INR48_RS02265	COG2733	membrane
INR48_RS02270	COG2814	Major facilitator Superfamily
INR48_RS02280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
INR48_RS02285	COG5457	Domain of unknown function (DUF1127)
INR48_RS02305	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
INR48_RS02325	COG0523	cobalamin synthesis protein
INR48_RS02330	COG2879	small protein
INR48_RS02335	COG1966	Carbon starvation protein
INR48_RS02340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
INR48_RS02345	COG2368	4-hydroxyphenylacetate
INR48_RS02350	COG1234	tRNA 3'-trailer cleavage
INR48_RS02370	COG3971	2-oxopent-4-enoate hydratase activity
INR48_RS02380	COG3384	dioxygenase
INR48_RS02385	COG1012	belongs to the aldehyde dehydrogenase family
INR48_RS02390	COG0179	Fumarylacetoacetate (FAA) hydrolase
INR48_RS02395	COG1846	Transcriptional regulator
INR48_RS02400	COG0840	transmembrane signaling receptor activity
INR48_RS02405	COG2271	Major facilitator Superfamily
INR48_RS02410	COG1802	Transcriptional regulator
INR48_RS02415	COG1063	alcohol dehydrogenase
INR48_RS02430	COG1484	DNA-dependent DNA replication
INR48_RS02445	COG2966	Psort location CytoplasmicMembrane, score
INR48_RS02450	COG2197	response regulator
INR48_RS02455	COG2197	response regulator
INR48_RS02460	COG4114	ferric iron reductase
INR48_RS02490	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
INR48_RS02495	COG0456	acetyltransferase
INR48_RS02500	COG1011	Hydrolase
INR48_RS02510	COG2823	Periplasmic or secreted lipoprotein
INR48_RS02520	COG4667	esterase of the alpha-beta hydrolase superfamily
INR48_RS02525	COG0084	hydrolase, TatD family'
INR48_RS02530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INR48_RS02535	COG1328	CTP reductase activity
INR48_RS02570	COG3726	membrane protein affecting hemolysin expression
INR48_RS02575	COG0560	Phosphoserine phosphatase
INR48_RS02580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
INR48_RS02585	COG3172	ATPase kinase involved in NAD metabolism
INR48_RS02585	COG1056	cytidyltransferase-related domain
INR48_RS02590	COG1902	pentaerythritol trinitrate reductase activity
INR48_RS02605	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS02615	COG0583	DNA-binding transcription factor activity
INR48_RS02620	COG0488	(ABC) transporter
INR48_RS02625	COG0741	lytic transglycosylase activity
INR48_RS02645	COG3708	Transcriptional regulator
INR48_RS02645	COG2207	Transcriptional regulator
INR48_RS02650	COG3045	CreA protein
INR48_RS02655	COG0745	RESPONSE REGULATOR receiver
INR48_RS02660	COG2205	protein histidine kinase activity
INR48_RS02665	COG4452	Inner membrane protein CreD
INR48_RS02670	COG0745	RESPONSE REGULATOR receiver
INR48_RS02680	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
INR48_RS02690	COG0460	homoserine dehydrogenase
INR48_RS02690	COG0527	aspartate kinase activity
INR48_RS02700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
INR48_RS02715	COG1115	amino acid carrier protein
INR48_RS02725	COG0521	Mo-molybdopterin cofactor biosynthetic process
INR48_RS02730	COG1584	GPR1 FUN34 yaaH family protein
INR48_RS02735	COG4735	regulation of single-species biofilm formation
INR48_RS02765	COG0583	DNA-binding transcription factor activity
INR48_RS02775	COG3188	usher protein
INR48_RS02780	COG3121	Chaperone
INR48_RS02805	COG0196	riboflavin kinase activity
INR48_RS02820	COG1047	Peptidyl-prolyl cis-trans
INR48_RS02840	COG0505	Belongs to the CarA family
INR48_RS02845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
INR48_RS02895	COG0644	oxidoreductase
INR48_RS02900	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
INR48_RS02905	COG2271	Major facilitator Superfamily
INR48_RS02920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
INR48_RS02945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INR48_RS02950	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
INR48_RS02955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
INR48_RS02960	COG1357	PFAM Pentapeptide repeats (8 copies)
INR48_RS02970	COG0564	pseudouridine synthase activity
INR48_RS02980	COG0417	DNA replication proofreading
INR48_RS02985	COG0235	Class ii aldolase
INR48_RS03000	COG4977	sequence-specific DNA binding
INR48_RS03005	COG0586	Pfam SNARE associated Golgi protein
INR48_RS03015	COG1178	ABC-type Fe3 transport system permease component
INR48_RS03020	COG4143	(ABC) transporter
INR48_RS03065	COG0583	DNA-binding transcription factor activity
INR48_RS03075	COG0028	Belongs to the TPP enzyme family
INR48_RS03080	COG0440	acetolactate synthase activity
INR48_RS03090	COG1609	Transcriptional regulator
INR48_RS03105	COG3116	cell division
INR48_RS03110	COG0768	penicillin binding
INR48_RS03115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
INR48_RS03120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
INR48_RS03135	COG0772	Belongs to the SEDS family
INR48_RS03150	COG1181	Belongs to the D-alanine--D-alanine ligase family
INR48_RS03155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
INR48_RS03160	COG0849	cell division
INR48_RS03165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
INR48_RS03185	COG0494	nUDIX hydrolase
INR48_RS03200	COG0237	dephospho-CoA kinase activity
INR48_RS03215	COG1459	type II secretion system
INR48_RS03220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
INR48_RS03225	COG4969	Belongs to the N-Me-Phe pilin family
INR48_RS03230	COG0157	Belongs to the NadC ModD family
INR48_RS03235	COG3023	N-Acetylmuramoyl-L-alanine amidase
INR48_RS03240	COG3725	Membrane protein required for beta-lactamase induction
INR48_RS03250	COG2186	Transcriptional regulator
INR48_RS03255	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
INR48_RS03260	COG0508	dehydrogenase complex catalyzes the overall conversion of
INR48_RS03265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INR48_RS03270	COG3064	Membrane
INR48_RS03275	COG1049	propionate catabolic process, 2-methylcitrate cycle
INR48_RS03300	COG2132	Multicopper oxidase
INR48_RS03305	COG4993	Dehydrogenase
INR48_RS03310	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
INR48_RS03315	COG0288	reversible hydration of carbon dioxide
INR48_RS03320	COG1131	(ABC) transporter
INR48_RS03325	COG0842	Transport permease protein
INR48_RS03330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS03335	COG0726	polysaccharide deacetylase
INR48_RS03345	COG5464	transposase or invertase
INR48_RS03360	COG3539	Fimbrial protein
INR48_RS03365	COG3539	Fimbrial protein
INR48_RS03370	COG3539	Fimbrial protein
INR48_RS03375	COG3188	usher protein
INR48_RS03380	COG3121	Chaperone
INR48_RS03385	COG3539	Fimbrial protein
INR48_RS03390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
INR48_RS03395	COG0617	tRNA 3'-terminal CCA addition
INR48_RS03400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
INR48_RS03405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
INR48_RS03415	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
INR48_RS03420	COG1643	Atp-dependent helicase
INR48_RS03425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INR48_RS03430	COG4774	siderophore transport
INR48_RS03435	COG1120	ATPase activity
INR48_RS03440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
INR48_RS03445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INR48_RS03470	COG2860	membrane
INR48_RS03475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
INR48_RS03490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INR48_RS03495	COG3835	regulator
INR48_RS03515	COG0024	Methionine aminopeptidase
INR48_RS03540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
INR48_RS03545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
INR48_RS03550	COG0575	Belongs to the CDS family
INR48_RS03555	COG0750	zinc metalloprotease
INR48_RS03565	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
INR48_RS03570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
INR48_RS03595	COG0587	DNA-directed DNA polymerase activity
INR48_RS03605	COG1982	Orn Lys Arg decarboxylase major
INR48_RS03610	COG0346	lactoylglutathione lyase activity
INR48_RS03620	COG4568	rho-dependent transcription termination
INR48_RS03630	COG4681	YaeQ
INR48_RS03635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
INR48_RS03640	COG3015	lipoprotein NlpE involved in copper resistance
INR48_RS03645	COG0791	NLP P60 protein
INR48_RS03655	COG1720	tRNA m6t6A37 methyltransferase activity
INR48_RS03665	COG1464	Belongs to the NlpA lipoprotein family
INR48_RS03670	COG2011	ABC-type metal ion transport system permease component
INR48_RS03675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
INR48_RS03680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
INR48_RS03715	COG0656	L-ascorbic acid biosynthetic process
INR48_RS03720	COG0583	DNA-binding transcription factor activity
INR48_RS03730	COG2226	methyltransferase
INR48_RS03735	COG0741	lytic transglycosylase activity
INR48_RS03735	COG1388	LysM domain
INR48_RS03745	COG2226	methyltransferase
INR48_RS03755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
INR48_RS03880	COG5433	transposase activity
INR48_RS03895	COG5433	transposase activity
INR48_RS03910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INR48_RS03920	COG1960	acyl-CoA dehydrogenase activity
INR48_RS03930	COG0121	glutamine amidotransferase
INR48_RS03935	COG3034	peptidoglycan biosynthetic process
INR48_RS03940	COG0791	NLP P60 protein
INR48_RS03945	COG1943	Transposase
INR48_RS03965	COG2161	toxin-antitoxin pair type II binding
INR48_RS03975	COG0454	-acetyltransferase
INR48_RS03980	COG1690	Belongs to the RtcB family
INR48_RS03985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
INR48_RS04000	COG2195	Cleaves the N-terminal amino acid of tripeptides
INR48_RS04020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
INR48_RS04045	COG0583	DNA-binding transcription factor activity
INR48_RS04060	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
INR48_RS04065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
INR48_RS04070	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
INR48_RS04085	COG2080	2 iron, 2 sulfur cluster binding
INR48_RS04090	COG3477	response to acidic pH
INR48_RS04095	COG0727	PFAM Uncharacterised protein family (UPF0153)
INR48_RS04100	COG3121	Chaperone
INR48_RS04150	COG1902	pentaerythritol trinitrate reductase activity
INR48_RS04155	COG1073	alpha beta
INR48_RS04160	COG0583	DNA-binding transcription factor activity
INR48_RS04170	COG0667	Aldo Keto reductase
INR48_RS04175	COG0656	L-ascorbic acid biosynthetic process
INR48_RS04180	COG1388	LysM domain
INR48_RS04185	COG3708	Transcriptional regulator
INR48_RS04185	COG2207	Transcriptional regulator
INR48_RS04190	COG0656	L-ascorbic acid biosynthetic process
INR48_RS04195	COG3059	membrane
INR48_RS04205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INR48_RS04210	COG2207	Transcriptional regulator
INR48_RS04215	COG0247	lactate metabolic process
INR48_RS04220	COG1139	Iron-sulfur cluster binding protein
INR48_RS04225	COG1556	Lactate utilization protein
INR48_RS04250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
INR48_RS04255	COG2771	luxR family
INR48_RS04255	COG2200	EAL domain
INR48_RS04260	COG0583	DNA-binding transcription factor activity
INR48_RS04270	COG0666	response to abiotic stimulus
INR48_RS04280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
INR48_RS04285	COG1304	FMN binding
INR48_RS04290	COG0549	Belongs to the carbamate kinase family
INR48_RS04295	COG0402	S-adenosylhomocysteine deaminase activity
INR48_RS04305	COG1064	alcohol dehydrogenase
INR48_RS04320	COG1280	lysine exporter protein (LysE YggA)
INR48_RS04330	COG3829	transcription factor binding
INR48_RS04335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
INR48_RS04340	COG0372	Belongs to the citrate synthase family
INR48_RS04345	COG2079	MmgE PrpD family protein
INR48_RS04350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
INR48_RS04355	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
INR48_RS04360	COG0402	S-adenosylhomocysteine deaminase activity
INR48_RS04365	COG0583	DNA-binding transcription factor activity
INR48_RS04370	COG0288	reversible hydration of carbon dioxide
INR48_RS04380	COG2807	transmembrane transport
INR48_RS04385	COG0110	maltose O-acetyltransferase activity
INR48_RS04390	COG2223	nitrite transmembrane transporter activity
INR48_RS04400	COG1609	Transcriptional regulator
INR48_RS04405	COG1414	Transcriptional regulator
INR48_RS04440	COG2814	Major facilitator Superfamily
INR48_RS04445	COG3122	Protein conserved in bacteria
INR48_RS04475	COG1215	transferase activity, transferring glycosyl groups
INR48_RS04480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
INR48_RS04485	COG4521	taurine ABC transporter
INR48_RS04490	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
INR48_RS04495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
INR48_RS04500	COG2175	clavaminate synthase activity
INR48_RS04505	COG0113	porphobilinogen synthase activity
INR48_RS04510	COG3468	outer membrane autotransporter barrel domain protein
INR48_RS04515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
INR48_RS04520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
INR48_RS04525	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
INR48_RS04545	COG1181	Belongs to the D-alanine--D-alanine ligase family
INR48_RS04560	COG1785	Belongs to the alkaline phosphatase family
INR48_RS04570	COG3706	GGDEF domain
INR48_RS04575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
INR48_RS04595	COG4126	flavin adenine dinucleotide binding
INR48_RS04620	COG1940	carbohydrate kinase activity
INR48_RS04625	COG2814	Major facilitator Superfamily
INR48_RS04630	COG0419	ATPase involved in DNA repair
INR48_RS04635	COG0420	3'-5' exonuclease activity
INR48_RS04640	COG0745	RESPONSE REGULATOR receiver
INR48_RS04645	COG5002	protein histidine kinase activity
INR48_RS04650	COG1114	Component of the transport system for branched-chain amino acids
INR48_RS04655	COG1113	amino acid transport
INR48_RS04660	COG0366	Alpha amylase catalytic
INR48_RS04685	COG1862	Preprotein translocase
INR48_RS04690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
INR48_RS04695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
INR48_RS04700	COG1403	HNH endonuclease
INR48_RS04705	COG3248	Nucleoside-binding outer membrane protein
INR48_RS04710	COG4238	major outer membrane lipoprotein
INR48_RS04720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
INR48_RS04720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
INR48_RS04735	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
INR48_RS04740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
INR48_RS04750	COG0667	Aldo Keto reductase
INR48_RS04760	COG0142	geranyltranstransferase activity
INR48_RS04775	COG0693	protein deglycase activity
INR48_RS04780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
INR48_RS04790	COG2814	Major facilitator Superfamily
INR48_RS04800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
INR48_RS04805	COG1845	cytochrome c oxidase, subunit III
INR48_RS04810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
INR48_RS04815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
INR48_RS04820	COG2223	nitrite transmembrane transporter activity
INR48_RS04825	COG3056	Lipoprotein
INR48_RS04830	COG0271	Belongs to the BolA IbaG family
INR48_RS04850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
INR48_RS04855	COG0776	regulation of translation
INR48_RS04860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INR48_RS04865	COG1555	photosystem II stabilization
INR48_RS04870	COG0824	Thioesterase
INR48_RS04880	COG4533	DNA binding
INR48_RS04890	COG1522	sequence-specific DNA binding
INR48_RS04895	COG1132	(ABC) transporter
INR48_RS04900	COG1132	(ABC) transporter
INR48_RS04905	COG0347	Belongs to the P(II) protein family
INR48_RS04910	COG0004	ammonium transporteR
INR48_RS04915	COG1946	Acyl-CoA thioesterase
INR48_RS04920	COG3126	Type III secretion system lipoprotein chaperone (YscW)
INR48_RS04925	COG3695	enzyme binding
INR48_RS04940	COG5507	3-demethylubiquinone-9 3-methyltransferase
INR48_RS04945	COG4943	cyclic-guanylate-specific phosphodiesterase activity
INR48_RS04955	COG0110	maltose O-acetyltransferase activity
INR48_RS04970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
INR48_RS04975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INR48_RS04980	COG1309	transcriptional regulator
INR48_RS04985	COG3264	Mechanosensitive ion channel
INR48_RS04985	COG1196	nuclear chromosome segregation
INR48_RS04995	COG3923	Primosomal replication protein n
INR48_RS05000	COG2832	Protein of unknown function (DUF454)
INR48_RS05010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
INR48_RS05045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INR48_RS05050	COG4651	solute:proton antiporter activity
INR48_RS05050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
INR48_RS05055	COG2223	nitrite transmembrane transporter activity
INR48_RS05060	COG0737	Belongs to the 5'-nucleotidase family
INR48_RS05065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
INR48_RS05070	COG3735	TraB family
INR48_RS05075	COG2217	Heavy metal translocating P-type atpase
INR48_RS05085	COG0531	amino acid
INR48_RS05110	COG0789	Transcriptional regulator
INR48_RS05135	COG1585	Membrane protein implicated in regulation of membrane protease activity
INR48_RS05140	COG0330	HflC and HflK could
INR48_RS05145	COG4619	ABC transporter
INR48_RS05150	COG0390	transport system, permease component
INR48_RS05155	COG3118	belongs to the thioredoxin family
INR48_RS05160	COG0300	oxidoreductase activity
INR48_RS05165	COG2755	lipolytic protein G-D-S-L family
INR48_RS05170	COG4181	ATPase activity
INR48_RS05175	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
INR48_RS05185	COG0583	DNA-binding transcription factor activity
INR48_RS05195	COG1414	Transcriptional regulator
INR48_RS05200	COG3960	tartronate-semialdehyde synthase activity
INR48_RS05205	COG3622	Belongs to the hyi family
INR48_RS05210	COG2084	Dehydrogenase
INR48_RS05215	COG1953	Uracil, thiamine, allantoin
INR48_RS05225	COG2233	PERMEase
INR48_RS05230	COG1929	Belongs to the glycerate kinase type-1 family
INR48_RS05235	COG3257	ureidoglycine aminohydrolase activity
INR48_RS05240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INR48_RS05245	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
INR48_RS05250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
INR48_RS05255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
INR48_RS05265	COG0549	Belongs to the carbamate kinase family
INR48_RS05270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
INR48_RS05275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
INR48_RS05285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
INR48_RS05295	COG1988	membrane-bound metal-dependent
INR48_RS05300	COG2501	S4 domain
INR48_RS05310	COG3539	Fimbrial protein
INR48_RS05315	COG3121	Chaperone
INR48_RS05320	COG3188	usher protein
INR48_RS05325	COG3539	Fimbrial protein
INR48_RS05330	COG3539	Fimbrial protein
INR48_RS05335	COG2197	response regulator
INR48_RS05345	COG2207	Transcriptional regulator
INR48_RS05355	COG4783	chaperone-mediated protein folding
INR48_RS05360	COG1215	transferase activity, transferring glycosyl groups
INR48_RS05425	COG5002	protein histidine kinase activity
INR48_RS05430	COG0745	RESPONSE REGULATOR receiver
INR48_RS05435	COG1538	Outer membrane efflux protein
INR48_RS05440	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INR48_RS05445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INR48_RS05450	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
INR48_RS05455	COG1113	amino acid transport
INR48_RS05460	COG0668	transmembrane transport
INR48_RS05465	COG0778	Nitroreductase
INR48_RS05470	COG2315	Protein conserved in bacteria
INR48_RS05495	COG2977	Belongs to the P-Pant transferase superfamily
INR48_RS05500	COG4771	TonB-dependent receptor
INR48_RS05505	COG2382	esterase
INR48_RS05510	COG3251	PFAM MbtH domain protein
INR48_RS05515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
INR48_RS05515	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
INR48_RS05520	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
INR48_RS05525	COG1120	ATPase activity
INR48_RS05530	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INR48_RS05535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INR48_RS05545	COG4592	Periplasmic binding protein
INR48_RS05550	COG1169	isochorismate synthase
INR48_RS05555	COG1021	2,3-dihydroxybenzoate-AMP ligase
INR48_RS05560	COG3433	isochorismatase activity
INR48_RS05560	COG1535	isochorismatase
INR48_RS05565	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS05575	COG1966	Carbon starvation protein
INR48_RS05580	COG2879	small protein
INR48_RS05585	COG0371	Dehydrogenase
INR48_RS05590	COG0436	Aminotransferase
INR48_RS05595	COG1475	DNA binding
INR48_RS05600	COG3969	phosphoadenosine phosphosulfate
INR48_RS05605	COG0583	DNA-binding transcription factor activity
INR48_RS05610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
INR48_RS05615	COG0450	alkyl hydroperoxide reductase
INR48_RS05620	COG3634	alkyl hydroperoxide reductase activity
INR48_RS05625	COG0589	response to stress
INR48_RS05630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
INR48_RS05635	COG3719	Belongs to the RNase T2 family
INR48_RS05640	COG0471	metal ion transport
INR48_RS05655	COG3051	citrate lyase alpha subunit
INR48_RS05660	COG2301	Belongs to the HpcH HpaI aldolase family
INR48_RS05670	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
INR48_RS05675	COG3290	protein histidine kinase activity
INR48_RS05680	COG4565	transcriptional regulatory protein
INR48_RS05685	COG3069	C4-dicarboxylate transmembrane transporter activity
INR48_RS05705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INR48_RS05710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
INR48_RS05720	COG0583	DNA-binding transcription factor activity
INR48_RS05735	COG1686	Belongs to the peptidase S11 family
INR48_RS05740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
INR48_RS05745	COG0772	Belongs to the SEDS family
INR48_RS05750	COG0768	penicillin binding
INR48_RS05760	COG0799	negative regulation of ribosome biogenesis
INR48_RS05765	COG0406	alpha-ribazole phosphatase activity
INR48_RS05775	COG1466	dna polymerase III delta subunit
INR48_RS05790	COG2888	peptidyl-tyrosine sulfation
INR48_RS05795	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
INR48_RS05805	COG2214	Heat shock protein DnaJ domain protein
INR48_RS05810	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
INR48_RS05820	COG2214	Heat shock protein DnaJ domain protein
INR48_RS05825	COG0443	Heat shock 70 kDa protein
INR48_RS05835	COG1126	abc transporter atp-binding protein
INR48_RS05840	COG0765	amino acid transport
INR48_RS05845	COG0765	amino acid transport
INR48_RS05850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INR48_RS05855	COG0815	Transfers the fatty acyl group on membrane lipoproteins
INR48_RS05860	COG4535	Mg2 and Co2 transporter CorC
INR48_RS05870	COG1702	phosphate starvation-inducible protein PhoH
INR48_RS05880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
INR48_RS05925	COG0367	asparagine synthase
INR48_RS05930	COG0647	UMP catabolic process
INR48_RS05935	COG1940	carbohydrate kinase activity
INR48_RS05935	COG1846	Transcriptional regulator
INR48_RS05940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
INR48_RS05950	COG2190	(PTS) system
INR48_RS05950	COG1263	PTS System
INR48_RS05950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS05970	COG0735	belongs to the Fur family
INR48_RS05980	COG0716	FMN binding
INR48_RS05990	COG0596	Alpha beta hydrolase
INR48_RS05995	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
INR48_RS06000	COG0033	Phosphoglucomutase
INR48_RS06010	COG0745	RESPONSE REGULATOR receiver
INR48_RS06015	COG2205	protein histidine kinase activity
INR48_RS06060	COG3272	Protein of unknown function (DUF1722)
INR48_RS06065	COG0415	Belongs to the DNA photolyase family
INR48_RS06075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
INR48_RS06080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
INR48_RS06085	COG1984	allophanate hydrolase subunit 2
INR48_RS06100	COG3180	Ammonia monooxygenase
INR48_RS06105	COG3539	Fimbrial protein
INR48_RS06110	COG3121	Chaperone
INR48_RS06115	COG3188	usher protein
INR48_RS06120	COG3539	Fimbrial protein
INR48_RS06125	COG0372	Belongs to the citrate synthase family
INR48_RS06135	COG2009	succinate dehydrogenase
INR48_RS06140	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
INR48_RS06145	COG1053	succinate dehydrogenase
INR48_RS06150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
INR48_RS06155	COG0567	Dehydrogenase, E1 component
INR48_RS06160	COG0508	dehydrogenase complex catalyzes the overall conversion of
INR48_RS06170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
INR48_RS06180	COG0583	DNA-binding transcription factor activity
INR48_RS06185	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
INR48_RS06190	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
INR48_RS06190	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
INR48_RS06195	COG1301	dicarboxylic acid transport
INR48_RS06210	COG3799	methylaspartate ammonia-lyase activity
INR48_RS06215	COG4865	methylaspartate mutase activity
INR48_RS06225	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
INR48_RS06240	COG1271	oxidase subunit
INR48_RS06245	COG1294	oxidase, subunit
INR48_RS06250	COG4890	Cyd operon protein YbgT
INR48_RS06255	COG3790	cyd operon protein YbgE
INR48_RS06260	COG0824	Thioesterase
INR48_RS06265	COG0811	peptide transport
INR48_RS06270	COG0848	biopolymer transport protein
INR48_RS06275	COG3064	Membrane
INR48_RS06285	COG2885	chlorophyll binding
INR48_RS06290	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
INR48_RS06340	COG3201	nicotinamide mononucleotide transporter
INR48_RS06345	COG1230	cation diffusion facilitator family transporter
INR48_RS06355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
INR48_RS06365	COG2017	converts alpha-aldose to the beta-anomer
INR48_RS06375	COG1085	galactose-1-phosphate uridylyltransferase
INR48_RS06380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
INR48_RS06385	COG1119	ATPase activity
INR48_RS06390	COG2005	Transcriptional regulator
INR48_RS06390	COG3585	molybdate ion transport
INR48_RS06400	COG0725	ABC transporter, periplasmic molybdate-binding protein
INR48_RS06405	COG4149	molybdate abc transporter
INR48_RS06410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
INR48_RS06415	COG0561	phosphatase activity
INR48_RS06425	COG0583	DNA-binding transcription factor activity
INR48_RS06430	COG2828	Protein conserved in bacteria
INR48_RS06435	COG0471	metal ion transport
INR48_RS06440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
INR48_RS06445	COG4677	pectinesterase activity
INR48_RS06450	COG0582	viral genome integration into host DNA
INR48_RS06500	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
INR48_RS06505	COG5532	Uncharacterized conserved protein (DUF2303)
INR48_RS06550	COG1846	Transcriptional regulator
INR48_RS06565	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
INR48_RS06575	COG1403	HNH endonuclease
INR48_RS06625	COG1802	Transcriptional regulator
INR48_RS06625	COG4626	Terminase
INR48_RS06635	COG4695	Portal protein
INR48_RS06680	COG4386	tail sheath protein
INR48_RS06705	COG4228	DNA circulation
INR48_RS06725	COG3299	homolog of phage Mu protein gp47
INR48_RS06730	COG3778	Protein conserved in bacteria
INR48_RS06760	COG2246	polysaccharide biosynthetic process
INR48_RS06765	COG1881	PFAM PEBP family protein
INR48_RS06770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
INR48_RS06785	COG2226	methyltransferase
INR48_RS06790	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
INR48_RS06800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
INR48_RS06810	COG0521	Mo-molybdopterin cofactor biosynthetic process
INR48_RS06820	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
INR48_RS06825	COG0314	molybdopterin synthase activity
INR48_RS06830	COG0670	Belongs to the BI1 family
INR48_RS06835	COG0670	Belongs to the BI1 family
INR48_RS06840	COG0392	lysyltransferase activity
INR48_RS06845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INR48_RS06850	COG3568	Endonuclease Exonuclease Phosphatase
INR48_RS06860	COG0842	Transport permease protein
INR48_RS06865	COG0842	Transport permease protein
INR48_RS06870	COG1131	(ABC) transporter
INR48_RS06880	COG1309	transcriptional regulator
INR48_RS06885	COG0513	Belongs to the DEAD box helicase family
INR48_RS06890	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
INR48_RS06895	COG1199	ATP-dependent helicase activity
INR48_RS06900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
INR48_RS06905	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
INR48_RS06915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
INR48_RS06940	COG0668	transmembrane transport
INR48_RS06945	COG1126	abc transporter atp-binding protein
INR48_RS06950	COG0765	amino acid transport
INR48_RS06955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INR48_RS06965	COG5006	permease, DMT superfamily
INR48_RS06975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INR48_RS06980	COG2194	sulfuric ester hydrolase activity
INR48_RS06990	COG1321	iron dependent repressor
INR48_RS06995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
INR48_RS07000	COG1376	ErfK ybiS ycfS ynhG family protein
INR48_RS07005	COG0488	(ABC) transporter
INR48_RS07015	COG2271	Major facilitator Superfamily
INR48_RS07030	COG0561	phosphatase activity
INR48_RS07035	COG1882	Formate acetyltransferase
INR48_RS07040	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INR48_RS07045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
INR48_RS07050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
INR48_RS07055	COG0303	'Molybdopterin
INR48_RS07060	COG1446	asparaginase
INR48_RS07070	COG0747	negative chemotaxis
INR48_RS07085	COG2200	EAL domain
INR48_RS07090	COG2199	diguanylate cyclase activity
INR48_RS07115	COG2133	pyrroloquinoline quinone binding
INR48_RS07120	COG0625	glutathione transferase activity
INR48_RS07125	COG1686	Belongs to the peptidase S11 family
INR48_RS07130	COG1349	DNA-binding transcription factor activity
INR48_RS07135	COG0671	phosphoesterase, PA-phosphatase related
INR48_RS07140	COG2814	Major facilitator Superfamily
INR48_RS07150	COG0561	phosphatase activity
INR48_RS07155	COG0738	Major facilitator superfamily
INR48_RS07160	COG3226	Transcriptional regulator
INR48_RS07165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
INR48_RS07205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
INR48_RS07250	COG4695	Portal protein
INR48_RS07345	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
INR48_RS07355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
INR48_RS07410	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
INR48_RS07420	COG0778	Nitroreductase
INR48_RS07435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
INR48_RS07440	COG3842	ATPase activity
INR48_RS07445	COG1176	ABC-type spermidine putrescine transport system, permease component I
INR48_RS07450	COG1177	transmembrane transport
INR48_RS07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INR48_RS07485	COG4160	amino acid transport
INR48_RS07490	COG4215	(ABC) transporter
INR48_RS07495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INR48_RS07500	COG1126	abc transporter atp-binding protein
INR48_RS07520	COG3023	N-Acetylmuramoyl-L-alanine amidase
INR48_RS07525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INR48_RS07530	COG0702	epimerase
INR48_RS07535	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
INR48_RS07540	COG0028	Belongs to the TPP enzyme family
INR48_RS07545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
INR48_RS07555	COG2431	L-lysine efflux transmembrane transporter activity
INR48_RS07560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
INR48_RS07565	COG3593	DNA synthesis involved in DNA repair
INR48_RS07570	COG2990	Protein conserved in bacteria
INR48_RS07575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INR48_RS07585	COG1278	Cold shock
INR48_RS07595	COG0542	response to heat
INR48_RS07620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
INR48_RS07625	COG4988	ABC transporter
INR48_RS07630	COG0492	ferredoxin-NADP+ reductase activity
INR48_RS07635	COG1522	sequence-specific DNA binding
INR48_RS07640	COG1674	ftsk spoiiie
INR48_RS07640	COG1178	ABC-type Fe3 transport system permease component
INR48_RS07650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
INR48_RS07660	COG0243	molybdopterin cofactor binding
INR48_RS07665	COG0437	4 iron, 4 sulfur cluster binding
INR48_RS07670	COG3302	dmso reductase anchor subunit
INR48_RS07675	COG1335	isochorismatase
INR48_RS07685	COG0531	amino acid
INR48_RS07695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INR48_RS07700	COG1882	Formate acetyltransferase
INR48_RS07705	COG2116	formate transmembrane transporter activity
INR48_RS07710	COG1944	ATP diphosphatase activity
INR48_RS07715	COG2323	membrane
INR48_RS07730	COG0501	Belongs to the peptidase M48B family
INR48_RS07740	COG0539	negative regulation of cytoplasmic translation
INR48_RS07750	COG2333	competence protein COMEC
INR48_RS07750	COG0658	competence protein
INR48_RS07765	COG3214	Protein conserved in bacteria
INR48_RS07780	COG3173	Aminoglycoside phosphotransferase
INR48_RS07785	COG1434	Gram-negative-bacterium-type cell wall biogenesis
INR48_RS07790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
INR48_RS07800	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
INR48_RS07810	COG2989	Protein conserved in bacteria
INR48_RS07815	COG3108	Peptidase M15
INR48_RS07820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
INR48_RS07825	COG1448	Aminotransferase
INR48_RS07845	COG0308	aminopeptidase N
INR48_RS07860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
INR48_RS07870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
INR48_RS07875	COG0431	NADPH-dependent FMN reductase
INR48_RS07890	COG3217	Mosc domain protein beta barrel domain protein
INR48_RS07890	COG0633	Ferredoxin
INR48_RS07900	COG0488	(ABC) transporter
INR48_RS07905	COG2995	paraquat-inducible protein a
INR48_RS07910	COG3008	intermembrane lipid transfer
INR48_RS07910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
INR48_RS07915	COG3009	Protein conserved in bacteria
INR48_RS07920	COG3130	regulation of translation
INR48_RS07930	COG1067	ATP-dependent peptidase activity
INR48_RS07940	COG2885	chlorophyll binding
INR48_RS07940	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INR48_RS07950	COG3070	regulator of competence-specific genes
INR48_RS07955	COG1289	transmembrane transporter activity
INR48_RS07960	COG3304	Inner membrane component domain
INR48_RS07965	COG0210	DNA helicase
INR48_RS07980	COG1832	CoA-binding protein
INR48_RS07995	COG1254	Belongs to the acylphosphatase family
INR48_RS08000	COG2920	part of a sulfur-relay system
INR48_RS08005	COG0670	Belongs to the BI1 family
INR48_RS08015	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
INR48_RS08020	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
INR48_RS08025	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
INR48_RS08030	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
INR48_RS08035	COG1999	signal sequence binding
INR48_RS08040	COG1773	rubredoxin
INR48_RS08045	COG1271	oxidase subunit
INR48_RS08050	COG1294	oxidase, subunit
INR48_RS08065	COG1278	Cold shock
INR48_RS08070	COG1278	Cold shock
INR48_RS08090	COG0348	domain, Protein
INR48_RS08095	COG0784	Response regulator, receiver
INR48_RS08095	COG2205	protein histidine kinase activity
INR48_RS08095	COG2198	Histidine kinase
INR48_RS08100	COG1879	ABC-type sugar transport system periplasmic component
INR48_RS08105	COG0745	RESPONSE REGULATOR receiver
INR48_RS08110	COG3005	denitrification pathway
INR48_RS08115	COG0243	molybdopterin cofactor binding
INR48_RS08155	COG3729	General stress protein
INR48_RS08160	COG2233	PERMEase
INR48_RS08195	COG1309	transcriptional regulator
INR48_RS08200	COG0506	proline dehydrogenase activity
INR48_RS08200	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
INR48_RS08200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
INR48_RS08210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INR48_RS08225	COG2822	iron ion transport
INR48_RS08235	COG1702	phosphate starvation-inducible protein PhoH
INR48_RS08260	COG3381	protein complex oligomerization
INR48_RS08270	COG1462	curli production assembly transport component CsgG
INR48_RS08285	COG2197	response regulator
INR48_RS08310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
INR48_RS08315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INR48_RS08330	COG2943	transferase activity, transferring hexosyl groups
INR48_RS08335	COG5645	(Lipo)protein
INR48_RS08350	COG1560	Kdo2-lipid A biosynthetic process
INR48_RS08365	COG3038	cytochrome b561
INR48_RS08400	COG2999	glutathione oxidoreductase activity
INR48_RS08410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
INR48_RS08420	COG0673	inositol 2-dehydrogenase activity
INR48_RS08425	COG0728	peptidoglycan biosynthetic process
INR48_RS08430	COG3418	PFAM FlgN family protein
INR48_RS08435	COG2747	anti-sigma28 factor FlgM
INR48_RS08440	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
INR48_RS08445	COG1815	bacterial-type flagellum-dependent cell motility
INR48_RS08450	COG1558	bacterial-type flagellum-dependent cell motility
INR48_RS08455	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
INR48_RS08460	COG1749	Flagellar hook protein flgE
INR48_RS08465	COG4787	bacterial-type flagellum-dependent cell motility
INR48_RS08470	COG4786	Flagellar basal body rod
INR48_RS08485	COG3951	Flagellar rod assembly protein muramidase FlgJ
INR48_RS08485	COG1705	Flagellar rod assembly protein muramidase FlgJ
INR48_RS08490	COG1256	bacterial-type flagellum assembly
INR48_RS08495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
INR48_RS08510	COG1530	ribonuclease E activity
INR48_RS08515	COG0564	pseudouridine synthase activity
INR48_RS08520	COG0424	maF-like protein
INR48_RS08525	COG1399	metal-binding, possibly nucleic acid-binding protein
INR48_RS08545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
INR48_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS08560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INR48_RS08565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
INR48_RS08570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
INR48_RS08580	COG0470	DNA polymerase III
INR48_RS08585	COG0084	hydrolase, TatD family'
INR48_RS08590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS08590	COG1263	PTS System
INR48_RS08595	COG4773	Receptor
INR48_RS08600	COG0537	adenosine 5'-monophosphoramidase activity
INR48_RS08605	COG5633	Lipoprotein
INR48_RS08610	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
INR48_RS08630	COG1252	NADH dehydrogenase
INR48_RS08635	COG3134	Outer membrane lipoprotein
INR48_RS08640	COG1309	transcriptional regulator
INR48_RS08650	COG1376	ErfK ybiS ycfS ynhG family protein
INR48_RS08650	COG1388	LysM domain
INR48_RS08655	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
INR48_RS08660	COG4763	Acyl-transferase
INR48_RS08665	COG4591	ABC-type transport system involved in lipoprotein release permease component
INR48_RS08675	COG4591	ABC-type transport system involved in lipoprotein release permease component
INR48_RS08685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
INR48_RS08690	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
INR48_RS08700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
INR48_RS08705	COG1177	transmembrane transport
INR48_RS08715	COG3842	ATPase activity
INR48_RS08725	COG2850	peptidyl-arginine hydroxylation
INR48_RS08730	COG2205	protein histidine kinase activity
INR48_RS08740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
INR48_RS08760	COG1187	pseudouridine synthase activity
INR48_RS08765	COG0538	isocitrate dehydrogenase activity
INR48_RS08785	COG5562	phage envelope protein
INR48_RS08790	COG0789	Transcriptional regulator
INR48_RS08795	COG2200	EAL domain
INR48_RS08820	COG2200	EAL domain
INR48_RS08875	COG2894	cell division
INR48_RS08905	COG0179	Fumarylacetoacetate (FAA) hydrolase
INR48_RS08920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
INR48_RS08925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
INR48_RS08930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
INR48_RS08945	COG2719	SpoVR family
INR48_RS08955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
INR48_RS08975	COG1619	proteins homologs of microcin C7 resistance protein MccF
INR48_RS08985	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
INR48_RS09000	COG0157	Belongs to the NadC ModD family
INR48_RS09005	COG0500	methyltransferase
INR48_RS09010	COG1120	ATPase activity
INR48_RS09015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INR48_RS09030	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
INR48_RS09030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS09030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
INR48_RS09035	COG1461	Dihydroxyacetone kinase
INR48_RS09040	COG2376	Dihydroxyacetone kinase
INR48_RS09045	COG3284	Transcriptional regulator
INR48_RS09050	COG3468	outer membrane autotransporter barrel domain protein
INR48_RS09055	COG0012	GTP binding
INR48_RS09070	COG0659	secondary active sulfate transmembrane transporter activity
INR48_RS09075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
INR48_RS09100	COG2890	protein-(glutamine-N5) methyltransferase activity
INR48_RS09105	COG3094	Invasion gene expression up-regulator, SirB
INR48_RS09110	COG2912	Transglutaminase-like superfamily
INR48_RS09130	COG0387	Pfam Sodium calcium exchanger
INR48_RS09135	COG4572	Cation transport regulator
INR48_RS09140	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
INR48_RS09145	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
INR48_RS09150	COG4932	domain protein
INR48_RS09155	COG2197	response regulator
INR48_RS09160	COG3850	Histidine kinase
INR48_RS09165	COG2223	nitrite transmembrane transporter activity
INR48_RS09170	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
INR48_RS09175	COG1140	nitrate reductase beta subunit
INR48_RS09180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
INR48_RS09185	COG2181	nitrate reductase activity
INR48_RS09210	COG0788	formyltetrahydrofolate deformylase activity
INR48_RS09220	COG1752	Esterase of the alpha-beta hydrolase superfamily
INR48_RS09225	COG0745	RESPONSE REGULATOR receiver
INR48_RS09230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
INR48_RS09240	COG1435	thymidine kinase activity
INR48_RS09245	COG1454	alcohol dehydrogenase
INR48_RS09245	COG1012	belongs to the aldehyde dehydrogenase family
INR48_RS09250	COG2095	MarC family integral membrane protein
INR48_RS09260	COG4166	transmembrane transport
INR48_RS09265	COG0601	transmembrane transport
INR48_RS09270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INR48_RS09275	COG0444	Belongs to the ABC transporter superfamily
INR48_RS09280	COG4608	Belongs to the ABC transporter superfamily
INR48_RS09300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
INR48_RS09305	COG2350	Protein conserved in bacteria
INR48_RS09310	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
INR48_RS09315	COG1607	acyl-coa hydrolase
INR48_RS09335	COG3047	cAMP biosynthetic process
INR48_RS09340	COG3685	Protein conserved in bacteria
INR48_RS09345	COG3685	Protein conserved in bacteria
INR48_RS09350	COG3729	General stress protein
INR48_RS09365	COG0135	phosphoribosylanthranilate isomerase activity
INR48_RS09365	COG0134	indole-3-glycerol-phosphate synthase activity
INR48_RS09370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
INR48_RS09370	COG0512	Glutamine amidotransferase of anthranilate synthase
INR48_RS09375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
INR48_RS09385	COG0613	PHP domain protein
INR48_RS09390	COG0009	L-threonylcarbamoyladenylate synthase
INR48_RS09395	COG4907	membrane protein (DUF2207)
INR48_RS09400	COG1187	pseudouridine synthase activity
INR48_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS09415	COG0616	signal peptide processing
INR48_RS09425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INR48_RS09430	COG0583	DNA-binding transcription factor activity
INR48_RS09450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
INR48_RS09460	COG0671	phosphoesterase, PA-phosphatase related
INR48_RS09465	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
INR48_RS09470	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
INR48_RS09480	COG0023	Translation Initiation Factor
INR48_RS09490	COG1349	DNA-binding transcription factor activity
INR48_RS09500	COG5001	Diguanylate cyclase
INR48_RS09515	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
INR48_RS09515	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
INR48_RS09520	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
INR48_RS09525	COG2852	Protein conserved in bacteria
INR48_RS09530	COG4172	Belongs to the ABC transporter superfamily
INR48_RS09535	COG4172	Belongs to the ABC transporter superfamily
INR48_RS09540	COG4171	peptide transport system, permease
INR48_RS09545	COG4168	peptide transport system, permease
INR48_RS09550	COG4166	transmembrane transport
INR48_RS09560	COG0531	amino acid
INR48_RS09570	COG0174	glutamine synthetase
INR48_RS09575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
INR48_RS09580	COG1396	sequence-specific DNA binding
INR48_RS09580	COG1917	Cupin 2, conserved barrel domain protein
INR48_RS09585	COG1012	belongs to the aldehyde dehydrogenase family
INR48_RS09590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
INR48_RS09595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
INR48_RS09600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
INR48_RS09605	COG1842	Phage shock protein A
INR48_RS09615	COG1983	PspC domain protein
INR48_RS09625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
INR48_RS09630	COG3106	COG3106 Predicted ATPase
INR48_RS09640	COG3283	Transcriptional regulator of aromatic amino acids metabolism
INR48_RS09645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
INR48_RS09650	COG4948	Mandelate Racemase Muconate Lactonizing
INR48_RS09655	COG2866	Carboxypeptidase
INR48_RS09660	COG0702	epimerase
INR48_RS09665	COG1073	alpha beta
INR48_RS09670	COG0583	DNA-binding transcription factor activity
INR48_RS09675	COG4166	transmembrane transport
INR48_RS09680	COG0668	transmembrane transport
INR48_RS09685	COG3182	Iron-regulated membrane protein
INR48_RS09690	COG0589	response to stress
INR48_RS09695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
INR48_RS09700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
INR48_RS09705	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
INR48_RS09710	COG1473	amidohydrolase
INR48_RS09715	COG1473	amidohydrolase
INR48_RS09720	COG0583	DNA-binding transcription factor activity
INR48_RS09725	COG2840	Smr protein MutS2
INR48_RS09730	COG3706	GGDEF domain
INR48_RS09745	COG0513	Belongs to the DEAD box helicase family
INR48_RS09755	COG0589	response to stress
INR48_RS09760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
INR48_RS09765	COG0674	pyruvate-flavodoxin oxidoreductase activity
INR48_RS09765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INR48_RS09765	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
INR48_RS09765	COG1013	pyruvate-flavodoxin oxidoreductase activity
INR48_RS09770	COG3042	response to heat
INR48_RS09775	COG3187	Heat shock protein
INR48_RS09780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INR48_RS09785	COG2911	Protein conserved in bacteria
INR48_RS09795	COG3784	Protein of unknown function (DUF1318)
INR48_RS09805	COG0667	Aldo Keto reductase
INR48_RS09815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
INR48_RS09820	COG4589	Belongs to the CDS family
INR48_RS09825	COG2267	carboxylic ester hydrolase activity
INR48_RS09830	COG0671	phosphoesterase, PA-phosphatase related
INR48_RS09830	COG2453	phosphatase
INR48_RS09840	COG1643	Atp-dependent helicase
INR48_RS09855	COG1434	Gram-negative-bacterium-type cell wall biogenesis
INR48_RS09860	COG1012	belongs to the aldehyde dehydrogenase family
INR48_RS09865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
INR48_RS09870	COG3038	cytochrome b561
INR48_RS09885	COG0840	transmembrane signaling receptor activity
INR48_RS09890	COG0583	DNA-binding transcription factor activity
INR48_RS09895	COG5383	Protein conserved in bacteria
INR48_RS09905	COG2841	Protein conserved in bacteria
INR48_RS09910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
INR48_RS09915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
INR48_RS09920	COG1275	C4-dicarboxylate transporter malic acid transport protein
INR48_RS09925	COG0500	methyltransferase
INR48_RS09935	COG3135	benzoate transporter
INR48_RS09940	COG1396	sequence-specific DNA binding
INR48_RS09945	COG0826	peptidase U32
INR48_RS09955	COG1724	mRNA binding
INR48_RS09960	COG1598	PFAM Uncharacterised protein family UPF0150
INR48_RS09965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
INR48_RS09970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
INR48_RS09975	COG3842	ATPase activity
INR48_RS09980	COG1176	ABC-type spermidine putrescine transport system, permease component I
INR48_RS09985	COG1177	transmembrane transport
INR48_RS10015	COG3238	Protein conserved in bacteria
INR48_RS10020	COG1247	-acetyltransferase
INR48_RS10025	COG2130	NADP-dependent
INR48_RS10030	COG1802	Transcriptional regulator
INR48_RS10035	COG4772	TonB-dependent receptor
INR48_RS10040	COG3391	amine dehydrogenase activity
INR48_RS10045	COG1113	amino acid transport
INR48_RS10055	COG0625	glutathione transferase activity
INR48_RS10065	COG3501	Rhs element vgr protein
INR48_RS10095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
INR48_RS10100	COG2162	N-hydroxyarylamine O-acetyltransferase activity
INR48_RS10110	COG0384	phenazine biosynthesis protein PhzF
INR48_RS10115	COG2181	nitrate reductase activity
INR48_RS10120	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
INR48_RS10125	COG1140	nitrate reductase beta subunit
INR48_RS10130	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
INR48_RS10135	COG2223	nitrite transmembrane transporter activity
INR48_RS10140	COG4886	Leucine-rich repeat (LRR) protein
INR48_RS10145	COG4886	Leucine-rich repeat (LRR) protein
INR48_RS10155	COG0697	spore germination
INR48_RS10165	COG0437	4 iron, 4 sulfur cluster binding
INR48_RS10170	COG2864	formate dehydrogenase
INR48_RS10175	COG3093	addiction module antidote protein HigA
INR48_RS10185	COG1064	alcohol dehydrogenase
INR48_RS10205	COG1764	response to oxidative stress
INR48_RS10210	COG4608	Belongs to the ABC transporter superfamily
INR48_RS10215	COG0444	Belongs to the ABC transporter superfamily
INR48_RS10220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INR48_RS10225	COG0601	transmembrane transport
INR48_RS10230	COG0747	negative chemotaxis
INR48_RS10235	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
INR48_RS10240	COG2199	diguanylate cyclase activity
INR48_RS10240	COG2202	Pas domain
INR48_RS10240	COG2200	EAL domain
INR48_RS10255	COG1649	PFAM Uncharacterised BCR, COG1649
INR48_RS10260	COG0531	amino acid
INR48_RS10265	COG0076	glutamate decarboxylase activity
INR48_RS10270	COG0612	Peptidase, M16
INR48_RS10275	COG4771	TonB-dependent receptor
INR48_RS10280	COG4178	(ABC) transporter
INR48_RS10290	COG0641	radical SAM
INR48_RS10300	COG2207	Transcriptional regulator
INR48_RS10310	COG0243	molybdopterin cofactor binding
INR48_RS10315	COG3539	Fimbrial protein
INR48_RS10320	COG3539	Fimbrial protein
INR48_RS10325	COG3539	Fimbrial protein
INR48_RS10330	COG3188	usher protein
INR48_RS10340	COG3539	Fimbrial protein
INR48_RS10360	COG0667	Aldo Keto reductase
INR48_RS10365	COG2249	NAD(P)H dehydrogenase (quinone) activity
INR48_RS10385	COG0656	L-ascorbic acid biosynthetic process
INR48_RS10405	COG3550	peptidyl-serine autophosphorylation
INR48_RS10410	COG1396	sequence-specific DNA binding
INR48_RS10470	COG3781	membrane
INR48_RS10480	COG2199	diguanylate cyclase activity
INR48_RS10490	COG2066	Belongs to the glutaminase family
INR48_RS10495	COG1012	belongs to the aldehyde dehydrogenase family
INR48_RS10500	COG0583	DNA-binding transcription factor activity
INR48_RS10520	COG1846	Transcriptional regulator
INR48_RS10525	COG4977	sequence-specific DNA binding
INR48_RS10535	COG0697	spore germination
INR48_RS10540	COG2814	Major facilitator Superfamily
INR48_RS10550	COG3706	GGDEF domain
INR48_RS10555	COG3111	PFAM Bacterial OB fold (BOF) protein
INR48_RS10560	COG0339	signal peptide processing
INR48_RS10565	COG4221	oxidoreductase activity
INR48_RS10570	COG1802	Transcriptional regulator
INR48_RS10580	COG0246	Mannitol dehydrogenase
INR48_RS10585	COG0477	Major facilitator Superfamily
INR48_RS10590	COG1063	alcohol dehydrogenase
INR48_RS10595	COG4948	Mandelate Racemase Muconate Lactonizing
INR48_RS10610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
INR48_RS10625	COG0243	molybdopterin cofactor binding
INR48_RS10630	COG0243	molybdopterin cofactor binding
INR48_RS10635	COG0437	4 iron, 4 sulfur cluster binding
INR48_RS10640	COG3302	dmso reductase anchor subunit
INR48_RS10645	COG3381	protein complex oligomerization
INR48_RS10655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
INR48_RS10660	COG1940	carbohydrate kinase activity
INR48_RS10665	COG0583	DNA-binding transcription factor activity
INR48_RS10670	COG2814	Major facilitator Superfamily
INR48_RS10685	COG3591	Belongs to the peptidase S1B family
INR48_RS10700	COG0628	permease
INR48_RS10705	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
INR48_RS10710	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
INR48_RS10720	COG0531	amino acid
INR48_RS10730	COG3136	membrane protein required for alginate biosynthesis
INR48_RS10735	COG0745	RESPONSE REGULATOR receiver
INR48_RS10740	COG2205	protein histidine kinase activity
INR48_RS10750	COG0114	fumarate hydratase activity
INR48_RS10755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
INR48_RS10755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
INR48_RS10760	COG1482	cell wall glycoprotein biosynthetic process
INR48_RS10765	COG5339	Protein conserved in bacteria
INR48_RS10780	COG3250	beta-galactosidase activity
INR48_RS10785	COG1309	transcriptional regulator
INR48_RS10790	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS10795	COG1609	Transcriptional regulator
INR48_RS10800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS10800	COG1263	PTS System
INR48_RS10805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
INR48_RS10815	COG0673	inositol 2-dehydrogenase activity
INR48_RS10855	COG4659	FMN binding
INR48_RS10865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
INR48_RS10870	COG3104	oligopeptide transport
INR48_RS10875	COG0625	glutathione transferase activity
INR48_RS10880	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
INR48_RS10895	COG3895	Periplasmic Protein
INR48_RS10905	COG3133	Outer membrane lipoprotein
INR48_RS10920	COG1566	PFAM secretion protein HlyD family protein
INR48_RS10925	COG1289	transmembrane transporter activity
INR48_RS10930	COG2032	superoxide dismutase activity
INR48_RS10935	COG4989	oxidoreductase activity
INR48_RS10940	COG3313	Fe-S protein
INR48_RS10945	COG1309	transcriptional regulator
INR48_RS10950	COG1902	pentaerythritol trinitrate reductase activity
INR48_RS10955	COG0346	lactoylglutathione lyase activity
INR48_RS10965	COG1201	RNA secondary structure unwinding
INR48_RS10970	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
INR48_RS10975	COG0791	NLP P60 protein
INR48_RS10980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
INR48_RS10985	COG2814	Major facilitator Superfamily
INR48_RS11000	COG0583	DNA-binding transcription factor activity
INR48_RS11005	COG2814	Major facilitator Superfamily
INR48_RS11010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
INR48_RS11015	COG0307	riboflavin synthase, alpha
INR48_RS11025	COG3468	outer membrane autotransporter barrel domain protein
INR48_RS11045	COG4529	Protein conserved in bacteria
INR48_RS11055	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
INR48_RS11060	COG0437	4 iron, 4 sulfur cluster binding
INR48_RS11070	COG2414	aldehyde ferredoxin oxidoreductase
INR48_RS11075	COG0437	4 iron, 4 sulfur cluster binding
INR48_RS11085	COG0469	pyruvate kinase activity
INR48_RS11090	COG4238	major outer membrane lipoprotein
INR48_RS11095	COG1376	ErfK ybiS ycfS ynhG family protein
INR48_RS11110	COG0719	Fe-S assembly protein
INR48_RS11115	COG0396	ATPase activity
INR48_RS11120	COG0719	Fe-S assembly protein
INR48_RS11125	COG0316	Belongs to the HesB IscA family
INR48_RS11135	COG2050	protein possibly involved in aromatic compounds catabolism
INR48_RS11140	COG0247	lactate metabolic process
INR48_RS11140	COG0277	FAD linked oxidase domain protein
INR48_RS11145	COG0628	permease
INR48_RS11160	COG0738	Major facilitator superfamily
INR48_RS11165	COG2271	Major facilitator Superfamily
INR48_RS11180	COG4670	ketone body catabolic process
INR48_RS11185	COG1960	acyl-CoA dehydrogenase activity
INR48_RS11190	COG2207	Transcriptional regulator
INR48_RS11190	COG1917	Cupin 2, conserved barrel domain protein
INR48_RS11195	COG2086	electron transfer activity
INR48_RS11200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
INR48_RS11205	COG0644	oxidoreductase
INR48_RS11210	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
INR48_RS11215	COG0318	PFAM AMP-dependent synthetase and ligase
INR48_RS11220	COG0574	Belongs to the PEP-utilizing enzyme family
INR48_RS11220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
INR48_RS11230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
INR48_RS11235	COG4256	Hemin uptake protein
INR48_RS11245	COG2200	EAL domain
INR48_RS11250	COG0791	NLP P60 protein
INR48_RS11260	COG0386	Belongs to the glutathione peroxidase family
INR48_RS11320	COG3137	Salt-induced outer membrane protein
INR48_RS11325	COG1105	Belongs to the carbohydrate kinase PfkB family
INR48_RS11335	COG3001	Fructosamine kinase
INR48_RS11345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
INR48_RS11350	COG1988	membrane-bound metal-dependent
INR48_RS11355	COG1823	symporter activity
INR48_RS11370	COG0753	catalase activity
INR48_RS11380	COG1486	melibiose metabolic process
INR48_RS11385	COG1917	Cupin 2, conserved barrel domain protein
INR48_RS11385	COG2169	Transcriptional regulator
INR48_RS11390	COG1447	Phosphotransferase system cellobiose-specific component IIA
INR48_RS11395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INR48_RS11400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INR48_RS11405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
INR48_RS11415	COG0322	excinuclease ABC activity
INR48_RS11425	COG3678	ATP-independent chaperone mediated protein folding
INR48_RS11455	COG0708	Exodeoxyribonuclease III
INR48_RS11460	COG0398	Pfam SNARE associated Golgi protein
INR48_RS11470	COG0398	Pfam SNARE associated Golgi protein
INR48_RS11475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
INR48_RS11480	COG4134	Bacterial extracellular solute-binding protein
INR48_RS11485	COG4135	transport system, permease component
INR48_RS11490	COG4136	ATPase activity
INR48_RS11495	COG2897	thiosulfate sulfurtransferase activity
INR48_RS11500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
INR48_RS11505	COG0494	nUDIX hydrolase
INR48_RS11515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
INR48_RS11520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INR48_RS11530	COG0778	Nitroreductase
INR48_RS11535	COG0616	signal peptide processing
INR48_RS11540	COG0252	asparaginase activity
INR48_RS11545	COG1335	isochorismatase
INR48_RS11550	COG2814	Major facilitator Superfamily
INR48_RS11555	COG1349	DNA-binding transcription factor activity
INR48_RS11560	COG0667	Aldo Keto reductase
INR48_RS11565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INR48_RS11570	COG0191	fructose-bisphosphate aldolase activity
INR48_RS11575	COG1063	alcohol dehydrogenase
INR48_RS11580	COG2271	Major facilitator Superfamily
INR48_RS11585	COG1063	alcohol dehydrogenase
INR48_RS11590	COG3139	Protein of unknown function (DUF1315)
INR48_RS11600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
INR48_RS11605	COG0676	glucose-6-phosphate 1-epimerase activity
INR48_RS11610	COG0656	L-ascorbic acid biosynthetic process
INR48_RS11615	COG3713	MltA-interacting MipA family protein
INR48_RS11620	COG2766	serine protein kinase
INR48_RS11630	COG2199	diguanylate cyclase activity
INR48_RS11635	COG2199	diguanylate cyclase activity
INR48_RS11640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
INR48_RS11655	COG2207	Transcriptional regulator
INR48_RS11660	COG2807	transmembrane transport
INR48_RS11665	COG3189	MarR family transcriptional regulator
INR48_RS11670	COG3042	response to heat
INR48_RS11675	COG2199	diguanylate cyclase activity
INR48_RS11675	COG2203	Gaf domain
INR48_RS11690	COG2261	transglycosylase associated protein
INR48_RS11700	COG3615	Tellurite resistance protein tehB
INR48_RS11710	COG0583	DNA-binding transcription factor activity
INR48_RS11715	COG0473	3-isopropylmalate dehydrogenase activity
INR48_RS11720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
INR48_RS11725	COG4638	Rieske (2fe-2S)
INR48_RS11730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
INR48_RS11735	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
INR48_RS11740	COG0318	PFAM AMP-dependent synthetase and ligase
INR48_RS11745	COG3065	identical protein binding
INR48_RS11750	COG1214	PFAM Peptidase M22, glycoprotease
INR48_RS11755	COG1199	ATP-dependent helicase activity
INR48_RS11760	COG0251	oxidation-reduction process
INR48_RS11775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
INR48_RS11785	COG1760	l-serine dehydratase
INR48_RS11790	COG2200	EAL domain
INR48_RS11795	COG1253	flavin adenine dinucleotide binding
INR48_RS11800	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS11800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS11805	COG3715	PTS system
INR48_RS11810	COG3716	PTS system mannose fructose sorbose family IID component
INR48_RS11825	COG2226	methyltransferase
INR48_RS11855	COG1414	Transcriptional regulator
INR48_RS11860	COG2814	Major facilitator Superfamily
INR48_RS11870	COG0793	Belongs to the peptidase S41A family
INR48_RS11880	COG1956	GAF domain-containing protein
INR48_RS11885	COG2995	paraquat-inducible protein a
INR48_RS11890	COG3008	intermembrane lipid transfer
INR48_RS11910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
INR48_RS11920	COG1276	copper resistance
INR48_RS11925	COG2372	response to copper ion
INR48_RS11935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INR48_RS11940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
INR48_RS11945	COG1770	oligopeptidase
INR48_RS11960	COG2979	Protein of unknown function (DUF533)
INR48_RS11970	COG3141	response to X-ray
INR48_RS11980	COG0800	Aldolase
INR48_RS11985	COG0129	dihydroxy-acid dehydratase activity
INR48_RS11990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
INR48_RS11995	COG1737	Transcriptional regulator
INR48_RS12000	COG0469	pyruvate kinase activity
INR48_RS12005	COG1560	Kdo2-lipid A biosynthetic process
INR48_RS12010	COG0739	heme binding
INR48_RS12015	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
INR48_RS12025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
INR48_RS12055	COG0217	transcriptional regulatory protein
INR48_RS12060	COG0494	nUDIX hydrolase
INR48_RS12070	COG1335	isochorismatase
INR48_RS12075	COG1801	Protein of unknown function DUF72
INR48_RS12080	COG3788	relative of glutathione S-transferase, MAPEG superfamily
INR48_RS12095	COG0243	molybdopterin cofactor binding
INR48_RS12100	COG3005	denitrification pathway
INR48_RS12110	COG3102	Protein conserved in bacteria
INR48_RS12125	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
INR48_RS12130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
INR48_RS12135	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
INR48_RS12140	COG0745	RESPONSE REGULATOR receiver
INR48_RS12150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
INR48_RS12155	COG0840	transmembrane signaling receptor activity
INR48_RS12160	COG0840	transmembrane signaling receptor activity
INR48_RS12165	COG0835	chemotaxis
INR48_RS12170	COG2198	Histidine kinase
INR48_RS12170	COG0643	Histidine kinase
INR48_RS12175	COG1360	Flagellar Motor Protein
INR48_RS12180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
INR48_RS12195	COG0589	response to stress
INR48_RS12205	COG1877	trehalose-phosphatase activity
INR48_RS12210	COG1172	Belongs to the binding-protein-dependent transport system permease family
INR48_RS12220	COG1879	ABC-type sugar transport system periplasmic component
INR48_RS12225	COG1528	Iron-storage protein
INR48_RS12245	COG1528	Iron-storage protein
INR48_RS12255	COG0814	amino acid
INR48_RS12260	COG3318	Belongs to the UPF0149 family
INR48_RS12260	COG3012	SEC-C Motif Domain Protein
INR48_RS12290	COG2197	response regulator
INR48_RS12305	COG2197	response regulator
INR48_RS12310	COG1126	abc transporter atp-binding protein
INR48_RS12315	COG0765	amino acid transport
INR48_RS12325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INR48_RS12335	COG1191	sigma factor activity
INR48_RS12345	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
INR48_RS12350	COG1516	flagellar protein fliS
INR48_RS12360	COG0366	Alpha amylase catalytic
INR48_RS12370	COG2391	methyltransferase activity
INR48_RS12375	COG0425	Belongs to the sulfur carrier protein TusA family
INR48_RS12380	COG2135	peptidase activity
INR48_RS12400	COG1766	The M ring may be actively involved in energy transduction
INR48_RS12405	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
INR48_RS12410	COG1317	bacterial-type flagellum organization
INR48_RS12415	COG1157	protein secretion by the type III secretion system
INR48_RS12420	COG2882	bacterial-type flagellum organization
INR48_RS12425	COG3144	bacterial-type flagellum assembly
INR48_RS12430	COG1580	Controls the rotational direction of flagella during chemotaxis
INR48_RS12435	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
INR48_RS12440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
INR48_RS12445	COG3190	flagellar
INR48_RS12450	COG1338	Plays a role in the flagellum-specific transport system
INR48_RS12455	COG1987	bacterial-type flagellum assembly
INR48_RS12460	COG1684	flagellar biosynthetic protein fliR
INR48_RS12465	COG2197	response regulator
INR48_RS12490	COG5475	Uncharacterized small protein (DUF2158)
INR48_RS12495	COG2354	Protein conserved in bacteria
INR48_RS12500	COG0697	spore germination
INR48_RS12505	COG3727	T/G mismatch-specific endonuclease activity
INR48_RS12510	COG0270	DNA (cytosine-5-)-methyltransferase activity
INR48_RS12515	COG1418	mRNA catabolic process
INR48_RS12525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
INR48_RS12540	COG2205	protein histidine kinase activity
INR48_RS12545	COG0745	RESPONSE REGULATOR receiver
INR48_RS12550	COG2351	hydroxyisourate hydrolase activity
INR48_RS12565	COG3443	Belongs to the bacterial solute-binding protein 9 family
INR48_RS12585	COG5301	cellulose 1,4-beta-cellobiosidase activity
INR48_RS12615	COG1196	nuclear chromosome segregation
INR48_RS12665	COG1030	water channel activity
INR48_RS12685	COG4220	transposase activity
INR48_RS12770	COG2207	Transcriptional regulator
INR48_RS12795	COG1403	HNH endonuclease
INR48_RS12835	COG1846	Transcriptional regulator
INR48_RS12860	COG1396	sequence-specific DNA binding
INR48_RS12895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
INR48_RS12925	COG2373	Large extracellular alpha-helical protein
INR48_RS12925	COG1388	LysM domain
INR48_RS12925	COG4932	domain protein
INR48_RS12935	COG0477	Major facilitator Superfamily
INR48_RS12940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
INR48_RS12945	COG0217	transcriptional regulatory protein
INR48_RS12955	COG0534	Mate efflux family protein
INR48_RS12965	COG0583	DNA-binding transcription factor activity
INR48_RS12970	COG0583	DNA-binding transcription factor activity
INR48_RS12980	COG1376	ErfK ybiS ycfS ynhG family protein
INR48_RS12995	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
INR48_RS13055	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
INR48_RS13070	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
INR48_RS13090	COG4656	Part of a membrane complex involved in electron transport
INR48_RS13115	COG1289	transmembrane transporter activity
INR48_RS13125	COG1686	Belongs to the peptidase S11 family
INR48_RS13130	COG2925	Exonuclease
INR48_RS13135	COG0531	amino acid
INR48_RS13145	COG0583	DNA-binding transcription factor activity
INR48_RS13150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INR48_RS13175	COG0131	Imidazoleglycerol-phosphate dehydratase
INR48_RS13175	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
INR48_RS13180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
INR48_RS13195	COG0140	phosphoribosyl-ATP diphosphatase activity
INR48_RS13195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
INR48_RS13205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
INR48_RS13210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
INR48_RS13245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
INR48_RS13255	COG0438	transferase activity, transferring glycosyl groups
INR48_RS13260	COG2327	Polysaccharide pyruvyl transferase
INR48_RS13265	COG2244	polysaccharide biosynthetic process
INR48_RS13270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
INR48_RS13275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INR48_RS13280	COG0662	Cupin 2, conserved barrel domain protein
INR48_RS13280	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
INR48_RS13285	COG0297	glycogen (starch) synthase activity
INR48_RS13290	COG1051	belongs to the nudix hydrolase family
INR48_RS13295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INR48_RS13300	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
INR48_RS13305	COG0110	maltose O-acetyltransferase activity
INR48_RS13310	COG1216	Glycosyl transferase, family 2
INR48_RS13320	COG0438	transferase activity, transferring glycosyl groups
INR48_RS13325	COG1045	serine acetyltransferase
INR48_RS13330	COG0463	Glycosyl transferase, family 2
INR48_RS13335	COG3206	protein involved in exopolysaccharide biosynthesis
INR48_RS13335	COG0489	protein tyrosine kinase activity
INR48_RS13340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
INR48_RS13345	COG1596	polysaccharide export
INR48_RS13355	COG1253	flavin adenine dinucleotide binding
INR48_RS13370	COG2982	Protein involved in outer membrane biogenesis
INR48_RS13380	COG0572	uridine kinase
INR48_RS13385	COG5002	protein histidine kinase activity
INR48_RS13385	COG5001	Diguanylate cyclase
INR48_RS13385	COG3447	MASE1 domain protein
INR48_RS13390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
INR48_RS13395	COG0443	Heat shock 70 kDa protein
INR48_RS13400	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
INR48_RS13405	COG3779	Protein conserved in bacteria
INR48_RS13410	COG0631	protein serine/threonine phosphatase activity
INR48_RS13415	COG4245	von Willebrand factor, type A
INR48_RS13460	COG2205	protein histidine kinase activity
INR48_RS13465	COG0745	RESPONSE REGULATOR receiver
INR48_RS13475	COG0826	peptidase U32
INR48_RS13495	COG1063	alcohol dehydrogenase
INR48_RS13500	COG3775	system Galactitol-specific IIC component
INR48_RS13505	COG3414	Phosphotransferase system galactitol-specific IIB component
INR48_RS13510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS13525	COG1830	Aldolase
INR48_RS13530	COG2211	Major facilitator Superfamily
INR48_RS13535	COG1397	ADP-ribosylglycohydrolase
INR48_RS13540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INR48_RS13545	COG2188	Transcriptional regulator
INR48_RS13550	COG3757	hydrolase, family 25
INR48_RS13555	COG0351	phosphomethylpyrimidine kinase
INR48_RS13575	COG5455	response to cobalt ion
INR48_RS13580	COG3539	Fimbrial protein
INR48_RS13585	COG3188	usher protein
INR48_RS13590	COG3121	Chaperone
INR48_RS13595	COG3539	Fimbrial protein
INR48_RS13605	COG0489	protein tyrosine kinase activity
INR48_RS13615	COG3831	ATPase activity
INR48_RS13620	COG3831	ATPase activity
INR48_RS13625	COG3831	ATPase activity
INR48_RS13635	COG0714	Associated with various cellular activities
INR48_RS13640	COG2425	protein containing a von Willebrand factor type A (vWA) domain
INR48_RS13645	COG3552	Protein containing von Willebrand factor type A (VWA) domain
INR48_RS13650	COG4715	Zinc finger, swim domain protein
INR48_RS13655	COG4808	Protein conserved in bacteria
INR48_RS13660	COG4807	Protein conserved in bacteria
INR48_RS13665	COG3279	Response regulator of the LytR AlgR family
INR48_RS13670	COG3275	phosphorelay sensor kinase activity
INR48_RS13675	COG0789	Transcriptional regulator
INR48_RS13685	COG1174	glycine betaine transport
INR48_RS13690	COG1125	glycine betaine transport
INR48_RS13695	COG1174	glycine betaine transport
INR48_RS13700	COG1732	Glycine betaine
INR48_RS13705	COG1472	Belongs to the glycosyl hydrolase 3 family
INR48_RS13710	COG0277	FAD linked oxidase domain protein
INR48_RS13715	COG1686	Belongs to the peptidase S11 family
INR48_RS13725	COG0586	Pfam SNARE associated Golgi protein
INR48_RS13730	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS13745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INR48_RS13755	COG1346	cytolysis
INR48_RS13765	COG2949	membrane
INR48_RS13775	COG0493	'glutamate synthase
INR48_RS13780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
INR48_RS13780	COG0167	dihydroorotate dehydrogenase activity
INR48_RS13785	COG4211	Belongs to the binding-protein-dependent transport system permease family
INR48_RS13790	COG1129	ABC transporter
INR48_RS13795	COG1879	ABC-type sugar transport system periplasmic component
INR48_RS13800	COG1609	Transcriptional regulator
INR48_RS13805	COG2311	Membrane
INR48_RS13815	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
INR48_RS13820	COG4771	TonB-dependent receptor
INR48_RS13825	COG0833	amino acid
INR48_RS13830	COG0583	DNA-binding transcription factor activity
INR48_RS13835	COG2855	membrane
INR48_RS13845	COG1522	sequence-specific DNA binding
INR48_RS13845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INR48_RS13850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
INR48_RS13860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
INR48_RS13865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
INR48_RS13870	COG2313	pseudouridylate synthase activity
INR48_RS13875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INR48_RS13880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INR48_RS13880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INR48_RS13880	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
INR48_RS13885	COG1105	Belongs to the carbohydrate kinase PfkB family
INR48_RS13890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS13890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS13895	COG2814	Major facilitator Superfamily
INR48_RS13910	COG0246	Mannitol dehydrogenase
INR48_RS13915	COG0523	cobalamin synthesis protein
INR48_RS13920	COG0671	phosphoesterase, PA-phosphatase related
INR48_RS13925	COG0791	NLP P60 protein
INR48_RS13930	COG2200	EAL domain
INR48_RS13935	COG4166	transmembrane transport
INR48_RS13940	COG4174	ABC transporter (Permease)
INR48_RS13945	COG4239	(ABC) transporter, permease
INR48_RS13950	COG4172	Belongs to the ABC transporter superfamily
INR48_RS13960	COG2814	Major facilitator Superfamily
INR48_RS13965	COG1187	pseudouridine synthase activity
INR48_RS13970	COG1061	Type III restriction enzyme res subunit
INR48_RS13990	COG3083	sulfuric ester hydrolase activity
INR48_RS14000	COG0582	viral genome integration into host DNA
INR48_RS14070	COG4220	transposase activity
INR48_RS14080	COG3468	outer membrane autotransporter barrel domain protein
INR48_RS14085	COG2197	response regulator
INR48_RS14090	COG3088	subunit of a heme lyase
INR48_RS14090	COG4235	cytochrome complex assembly
INR48_RS14095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INR48_RS14100	COG1138	Cytochrome C-type biogenesis protein
INR48_RS14110	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INR48_RS14115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INR48_RS14120	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INR48_RS14130	COG3005	denitrification pathway
INR48_RS14135	COG3043	anaerobic respiration
INR48_RS14140	COG0348	domain, Protein
INR48_RS14145	COG0437	4 iron, 4 sulfur cluster binding
INR48_RS14155	COG3062	negative regulation of establishment of protein localization
INR48_RS14160	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS14160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS14175	COG4615	Cyclic peptide transporter
INR48_RS14180	COG3145	DNA-N1-methyladenine dioxygenase activity
INR48_RS14185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
INR48_RS14185	COG2169	Transcriptional regulator
INR48_RS14190	COG1477	protein flavinylation
INR48_RS14195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
INR48_RS14200	COG0642	Histidine kinase
INR48_RS14200	COG2198	Histidine kinase
INR48_RS14205	COG2197	response regulator
INR48_RS14210	COG0784	Response regulator, receiver
INR48_RS14210	COG2205	protein histidine kinase activity
INR48_RS14215	COG3852	Histidine kinase
INR48_RS14220	COG2204	response regulator
INR48_RS14225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
INR48_RS14230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
INR48_RS14235	COG2031	fatty acid transporter
INR48_RS14240	COG0183	Belongs to the thiolase family
INR48_RS14245	COG4676	Protein conserved in bacteria
INR48_RS14250	COG5445	Predicted secreted protein (DUF2300)
INR48_RS14255	COG2373	Large extracellular alpha-helical protein
INR48_RS14260	COG3234	Protein of unknown function (DUF1175)
INR48_RS14265	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
INR48_RS14270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
INR48_RS14280	COG3468	outer membrane autotransporter barrel domain protein
INR48_RS14285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INR48_RS14290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INR48_RS14295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
INR48_RS14300	COG3642	lipopolysaccharide core region biosynthetic process
INR48_RS14305	COG2814	Major facilitator Superfamily
INR48_RS14310	COG0583	DNA-binding transcription factor activity
INR48_RS14320	COG0584	glycerophosphoryl diester phosphodiesterase
INR48_RS14325	COG2271	Major facilitator Superfamily
INR48_RS14330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
INR48_RS14340	COG0247	lactate metabolic process
INR48_RS14345	COG5464	transposase or invertase
INR48_RS14360	COG2271	Major facilitator Superfamily
INR48_RS14365	COG0675	Transposase, IS605 OrfB family
INR48_RS14435	COG0318	PFAM AMP-dependent synthetase and ligase
INR48_RS14445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
INR48_RS14460	COG1169	isochorismate synthase
INR48_RS14465	COG4575	ribosome binding
INR48_RS14470	COG2153	protein acetylation
INR48_RS14480	COG5160	protein modification by small protein removal
INR48_RS14485	COG2234	aminopeptidase activity
INR48_RS14500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INR48_RS14505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
INR48_RS14515	COG0839	Belongs to the complex I subunit 6 family
INR48_RS14530	COG1034	ATP synthesis coupled electron transport
INR48_RS14535	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
INR48_RS14540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
INR48_RS14560	COG0583	DNA-binding transcription factor activity
INR48_RS14565	COG0436	Aminotransferase
INR48_RS14575	COG0471	metal ion transport
INR48_RS14575	COG0490	domain, Protein
INR48_RS14580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
INR48_RS14595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
INR48_RS14600	COG0280	phosphate acetyltransferase
INR48_RS14600	COG0857	belongs to the CobB CobQ family
INR48_RS14605	COG1288	antiporter activity
INR48_RS14610	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
INR48_RS14615	COG0622	Phosphoesterase
INR48_RS14620	COG0625	glutathione transferase activity
INR48_RS14625	COG0625	glutathione transferase activity
INR48_RS14630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
INR48_RS14635	COG1090	epimerase
INR48_RS14640	COG5464	transposase or invertase
INR48_RS14645	COG4598	ABC transporter
INR48_RS14650	COG4160	amino acid transport
INR48_RS14655	COG4215	(ABC) transporter
INR48_RS14660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INR48_RS14665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INR48_RS14670	COG0163	prenyltransferase activity
INR48_RS14675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
INR48_RS14680	COG1286	toxin biosynthetic process
INR48_RS14685	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
INR48_RS14690	COG0285	dihydrofolate synthase activity
INR48_RS14700	COG0586	Pfam SNARE associated Golgi protein
INR48_RS14710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
INR48_RS14725	COG2814	Major facilitator Superfamily
INR48_RS14730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INR48_RS14745	COG3101	peptidyl-lysine hydroxylation
INR48_RS14750	COG0730	response to heat
INR48_RS14765	COG2890	protein-(glutamine-N5) methyltransferase activity
INR48_RS14780	COG3539	Fimbrial protein
INR48_RS14785	COG3539	Fimbrial protein
INR48_RS14790	COG3539	Fimbrial protein
INR48_RS14795	COG3121	Chaperone
INR48_RS14800	COG3188	usher protein
INR48_RS14805	COG3539	Fimbrial protein
INR48_RS14810	COG2062	phosphohistidine phosphatase, SixA
INR48_RS14825	COG3691	Protein conserved in bacteria
INR48_RS14830	COG2067	long-chain fatty acid transport protein
INR48_RS14840	COG2853	Lipoprotein
INR48_RS14845	COG2116	formate transmembrane transporter activity
INR48_RS14890	COG0477	Major facilitator Superfamily
INR48_RS14895	COG1566	PFAM secretion protein HlyD family protein
INR48_RS14900	COG2197	response regulator
INR48_RS14905	COG2198	Histidine kinase
INR48_RS14905	COG0784	Response regulator, receiver
INR48_RS14905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INR48_RS14905	COG2205	protein histidine kinase activity
INR48_RS14910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
INR48_RS14915	COG0679	Auxin Efflux Carrier
INR48_RS14920	COG0028	Belongs to the TPP enzyme family
INR48_RS14945	COG1560	Kdo2-lipid A biosynthetic process
INR48_RS14955	COG0436	Aminotransferase
INR48_RS14960	COG3275	phosphorelay sensor kinase activity
INR48_RS14965	COG3279	Response regulator of the LytR AlgR family
INR48_RS14970	COG2207	Transcriptional regulator
INR48_RS14980	COG1363	Peptidase, m42
INR48_RS14985	COG0006	proline dipeptidase activity
INR48_RS14990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INR48_RS14995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INR48_RS15020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
INR48_RS15025	COG2199	diguanylate cyclase activity
INR48_RS15025	COG2200	EAL domain
INR48_RS15040	COG3415	Transposase
INR48_RS15045	COG3415	Transposase
INR48_RS15080	COG0583	DNA-binding transcription factor activity
INR48_RS15085	COG0385	Bile acid
INR48_RS15090	COG3530	Putative quorum-sensing-regulated virulence factor
INR48_RS15110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
INR48_RS15115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS15120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
INR48_RS15125	COG2190	(PTS) system
INR48_RS15140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
INR48_RS15145	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
INR48_RS15150	COG4208	sulfate ABC transporter
INR48_RS15155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
INR48_RS15160	COG4150	thiosulfate binding
INR48_RS15165	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS15180	COG1263	PTS System
INR48_RS15180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS15185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
INR48_RS15190	COG2837	iron assimilation
INR48_RS15210	COG0860	N-Acetylmuramoyl-L-alanine amidase
INR48_RS15220	COG2207	Transcriptional regulator
INR48_RS15225	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
INR48_RS15230	COG4816	utilization protein
INR48_RS15240	COG4303	Ethanolamine ammonia lyase large subunit
INR48_RS15245	COG4819	ethanolamine utilization protein
INR48_RS15250	COG3192	ethanolamine utilization protein
INR48_RS15255	COG1454	alcohol dehydrogenase
INR48_RS15260	COG4820	ethanolamine utilization protein (EutJ)
INR48_RS15265	COG1012	belongs to the aldehyde dehydrogenase family
INR48_RS15270	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
INR48_RS15275	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
INR48_RS15280	COG0280	phosphate acetyltransferase
INR48_RS15285	COG4812	Cobalamin adenosyltransferase
INR48_RS15290	COG4766	ethanolamine catabolic process
INR48_RS15295	COG4917	ethanolamine utilization protein
INR48_RS15300	COG4810	utilization protein
INR48_RS15305	COG0281	malic enzyme
INR48_RS15305	COG0280	phosphate acetyltransferase
INR48_RS15310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
INR48_RS15315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
INR48_RS15320	COG5342	invasion associated locus B
INR48_RS15330	COG0493	'glutamate synthase
INR48_RS15330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS15335	COG3850	Histidine kinase
INR48_RS15340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
INR48_RS15350	COG1393	Belongs to the ArsC family
INR48_RS15365	COG0400	carboxylic ester hydrolase activity
INR48_RS15375	COG2321	neutral zinc metallopeptidase
INR48_RS15385	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
INR48_RS15395	COG2716	regulation of RNA biosynthetic process
INR48_RS15400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
INR48_RS15405	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS15410	COG0651	ATP synthesis coupled electron transport
INR48_RS15415	COG0650	Formate hydrogenlyase subunit 4
INR48_RS15420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
INR48_RS15425	COG4237	Hydrogenase 4 membrane
INR48_RS15430	COG0651	ATP synthesis coupled electron transport
INR48_RS15440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INR48_RS15445	COG3260	NADH ubiquinone oxidoreductase 20
INR48_RS15455	COG3604	Transcriptional regulator
INR48_RS15460	COG2116	formate transmembrane transporter activity
INR48_RS15465	COG0628	permease
INR48_RS15470	COG4783	chaperone-mediated protein folding
INR48_RS15475	COG1393	Belongs to the ArsC family
INR48_RS15485	COG2233	PERMEase
INR48_RS15500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
INR48_RS15505	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
INR48_RS15510	COG0248	Ppx GppA phosphatase
INR48_RS15515	COG2200	EAL domain
INR48_RS15530	COG3133	Outer membrane lipoprotein
INR48_RS15550	COG0517	IMP dehydrogenase activity
INR48_RS15550	COG0516	GMP reductase activity
INR48_RS15575	COG1645	bacterial-type flagellum-dependent swarming motility
INR48_RS15590	COG2976	Protein conserved in bacteria
INR48_RS15620	COG4953	penicillin-binding protein 1C
INR48_RS15625	COG2373	Large extracellular alpha-helical protein
INR48_RS15630	COG2897	thiosulfate sulfurtransferase activity
INR48_RS15645	COG2975	iron-sulfur cluster assembly
INR48_RS15650	COG0633	Ferredoxin
INR48_RS15670	COG0822	iron-sulfur transferase activity
INR48_RS15690	COG0483	inositol monophosphate 1-phosphatase activity
INR48_RS15695	COG1073	alpha beta
INR48_RS15700	COG3711	transcriptional antiterminator
INR48_RS15705	COG2814	Major facilitator Superfamily
INR48_RS15710	COG0583	DNA-binding transcription factor activity
INR48_RS15715	COG4638	Rieske (2fe-2S)
INR48_RS15740	COG2259	Doxx family
INR48_RS15745	COG2017	converts alpha-aldose to the beta-anomer
INR48_RS15750	COG1063	alcohol dehydrogenase
INR48_RS15755	COG1172	Belongs to the binding-protein-dependent transport system permease family
INR48_RS15760	COG1129	ABC transporter
INR48_RS15765	COG1879	ABC-type sugar transport system periplasmic component
INR48_RS15770	COG0457	Tetratricopeptide repeat
INR48_RS15775	COG1940	carbohydrate kinase activity
INR48_RS15785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
INR48_RS15785	COG1017	nitric oxide dioxygenase activity
INR48_RS15790	COG0347	Belongs to the P(II) protein family
INR48_RS15795	COG2204	response regulator
INR48_RS15800	COG3170	Tfp pilus assembly protein FimV
INR48_RS15805	COG2205	protein histidine kinase activity
INR48_RS15810	COG0047	phosphoribosylformylglycinamidine synthase activity
INR48_RS15810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
INR48_RS15820	COG0590	tRNA wobble adenosine to inosine editing
INR48_RS15825	COG0560	Phosphoserine phosphatase
INR48_RS15830	COG1737	Transcriptional regulator
INR48_RS15835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS15850	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
INR48_RS15870	COG0681	Belongs to the peptidase S26 family
INR48_RS15880	COG3086	response to oxidative stress
INR48_RS15885	COG3026	antisigma factor binding
INR48_RS15890	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
INR48_RS15895	COG1595	DNA-templated transcription, initiation
INR48_RS15905	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
INR48_RS15915	COG0513	Belongs to the DEAD box helicase family
INR48_RS15925	COG0583	DNA-binding transcription factor activity
INR48_RS15945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INR48_RS15950	COG3118	belongs to the thioredoxin family
INR48_RS15955	COG3148	PFAM DTW domain containing protein
INR48_RS15960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
INR48_RS15960	COG0045	succinate-CoA ligase (ADP-forming) activity
INR48_RS15960	COG1042	CoA-binding domain protein
INR48_RS15965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INR48_RS15970	COG5544	Lipoprotein
INR48_RS15975	COG0477	Major facilitator Superfamily
INR48_RS16000	COG0542	response to heat
INR48_RS16010	COG0564	pseudouridine synthase activity
INR48_RS16015	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
INR48_RS16020	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
INR48_RS16030	COG0077	Prephenate dehydratase
INR48_RS16030	COG1605	Chorismate mutase
INR48_RS16035	COG0287	Prephenate dehydrogenase
INR48_RS16035	COG1605	Chorismate mutase
INR48_RS16040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
INR48_RS16055	COG2199	diguanylate cyclase activity
INR48_RS16060	COG2885	chlorophyll binding
INR48_RS16085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
INR48_RS16090	COG4137	Cytochrome C assembly protein
INR48_RS16095	COG4536	flavin adenine dinucleotide binding
INR48_RS16110	COG0497	DNA recombination
INR48_RS16115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
INR48_RS16125	COG2867	negative regulation of translational initiation
INR48_RS16140	COG0582	viral genome integration into host DNA
INR48_RS16210	COG3732	PTS system glucitol sorbitol-specific
INR48_RS16225	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
INR48_RS16230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
INR48_RS16240	COG2190	(PTS) system
INR48_RS16240	COG1263	PTS System
INR48_RS16240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS16255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
INR48_RS16285	COG3468	outer membrane autotransporter barrel domain protein
INR48_RS16315	COG0366	Alpha amylase catalytic
INR48_RS16325	COG0579	oxidoreductase
INR48_RS16330	COG1012	belongs to the aldehyde dehydrogenase family
INR48_RS16335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
INR48_RS16340	COG1113	amino acid transport
INR48_RS16345	COG1802	Transcriptional regulator
INR48_RS16350	COG1652	LysM domain
INR48_RS16355	COG0401	homolog of Blt101
INR48_RS16360	COG0640	Transcriptional regulator
INR48_RS16365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
INR48_RS16370	COG2916	Histone family protein nucleoid-structuring protein H-NS
INR48_RS16385	COG4575	ribosome binding
INR48_RS16390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
INR48_RS16395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
INR48_RS16400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
INR48_RS16410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INR48_RS16415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INR48_RS16420	COG4175	Glycine betaine
INR48_RS16425	COG4176	ABC-type proline glycine betaine transport system permease component
INR48_RS16430	COG2113	Glycine betaine
INR48_RS16435	COG2814	Major facilitator Superfamily
INR48_RS16440	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
INR48_RS16450	COG1846	Transcriptional regulator
INR48_RS16455	COG1566	PFAM secretion protein HlyD family protein
INR48_RS16460	COG2814	Major facilitator Superfamily
INR48_RS16475	COG1238	metal cluster binding
INR48_RS16480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
INR48_RS16510	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
INR48_RS16530	COG1546	Belongs to the CinA family
INR48_RS16535	COG2951	lytic endotransglycosylase activity
INR48_RS16540	COG3730	PTS system glucitol sorbitol-specific
INR48_RS16545	COG3732	PTS system glucitol sorbitol-specific
INR48_RS16555	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS16560	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS16565	COG1349	DNA-binding transcription factor activity
INR48_RS16590	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
INR48_RS16595	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS16600	COG1609	Transcriptional regulator
INR48_RS16605	COG1263	PTS System
INR48_RS16605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS16610	COG2723	6-phospho-beta-galactosidase activity
INR48_RS16615	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
INR48_RS16625	COG3260	NADH ubiquinone oxidoreductase 20
INR48_RS16630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INR48_RS16635	COG3261	NADH dehydrogenase
INR48_RS16635	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
INR48_RS16640	COG0650	Formate hydrogenlyase subunit 4
INR48_RS16645	COG0651	ATP synthesis coupled electron transport
INR48_RS16650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS16660	COG0375	protein maturation
INR48_RS16665	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
INR48_RS16670	COG0298	carbon dioxide binding
INR48_RS16675	COG0409	Hydrogenase expression formation protein
INR48_RS16680	COG0309	Hydrogenase expression formation protein (HypE)
INR48_RS16685	COG3604	Transcriptional regulator
INR48_RS16725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
INR48_RS16735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
INR48_RS16740	COG0163	prenyltransferase activity
INR48_RS16750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INR48_RS16755	COG1388	LysM domain
INR48_RS16755	COG4942	peptidase
INR48_RS16810	COG2234	aminopeptidase activity
INR48_RS16815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
INR48_RS16835	COG1857	crispr-associated protein
INR48_RS16850	COG1203	CRISPR-associated helicase, Cas3
INR48_RS16875	COG0720	synthase
INR48_RS16880	COG0644	oxidoreductase
INR48_RS16885	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
INR48_RS16890	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
INR48_RS16895	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
INR48_RS16900	COG2086	electron transfer activity
INR48_RS16905	COG0477	Major facilitator Superfamily
INR48_RS16910	COG0277	FAD linked oxidase domain protein
INR48_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS16920	COG2223	nitrite transmembrane transporter activity
INR48_RS16925	COG1070	Carbohydrate kinase
INR48_RS16930	COG0602	queuosine metabolic process
INR48_RS16940	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
INR48_RS16950	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
INR48_RS16965	COG3956	TIGRFAM MazG family protein
INR48_RS16970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INR48_RS16980	COG3437	response regulator, receiver
INR48_RS16980	COG4999	Histidine kinase
INR48_RS16980	COG3850	Histidine kinase
INR48_RS16980	COG2205	protein histidine kinase activity
INR48_RS16985	COG4948	Mandelate Racemase Muconate Lactonizing
INR48_RS16990	COG4948	Mandelate Racemase Muconate Lactonizing
INR48_RS16995	COG2271	Major facilitator Superfamily
INR48_RS17000	COG0716	FMN binding
INR48_RS17005	COG0564	pseudouridine synthase activity
INR48_RS17010	COG3098	single-species biofilm formation
INR48_RS17025	COG1611	Belongs to the LOG family
INR48_RS17030	COG0814	amino acid
INR48_RS17035	COG1760	l-serine dehydratase
INR48_RS17045	COG1454	alcohol dehydrogenase
INR48_RS17050	COG0235	Class ii aldolase
INR48_RS17055	COG0738	Major facilitator superfamily
INR48_RS17065	COG1070	Carbohydrate kinase
INR48_RS17075	COG1349	DNA-binding transcription factor activity
INR48_RS17085	COG2363	Small membrane protein
INR48_RS17090	COG0583	DNA-binding transcription factor activity
INR48_RS17100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
INR48_RS17105	COG2166	iron-sulfur cluster assembly
INR48_RS17110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
INR48_RS17115	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
INR48_RS17135	COG0860	N-Acetylmuramoyl-L-alanine amidase
INR48_RS17140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
INR48_RS17140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
INR48_RS17145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
INR48_RS17150	COG1074	ATP-dependent DNA helicase activity
INR48_RS17160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
INR48_RS17165	COG4967	type IV pilus modification protein PilV
INR48_RS17175	COG4795	General secretion pathway protein
INR48_RS17180	COG2165	general secretion pathway protein
INR48_RS17195	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
INR48_RS17210	COG0861	Integral membrane protein TerC family
INR48_RS17220	COG0667	Aldo Keto reductase
INR48_RS17235	COG1609	Transcriptional regulator
INR48_RS17245	COG0583	DNA-binding transcription factor activity
INR48_RS17250	COG1794	racemase activity, acting on amino acids and derivatives
INR48_RS17255	COG2814	Major facilitator Superfamily
INR48_RS17260	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS17275	COG0814	amino acid
INR48_RS17280	COG2771	luxR family
INR48_RS17285	COG3710	Transcriptional regulator
INR48_RS17310	COG0457	Tetratricopeptide repeat
INR48_RS17315	COG0457	Tetratricopeptide repeat
INR48_RS17315	COG3710	Transcriptional regulator
INR48_RS17325	COG0741	lytic transglycosylase activity
INR48_RS17330	COG2197	response regulator
INR48_RS17430	COG2207	Transcriptional regulator
INR48_RS17440	COG3387	PFAM Glycoside hydrolase 15-related
INR48_RS17450	COG4942	peptidase
INR48_RS17455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
INR48_RS17460	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
INR48_RS17465	COG2080	2 iron, 2 sulfur cluster binding
INR48_RS17470	COG3829	transcription factor binding
INR48_RS17475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
INR48_RS17480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
INR48_RS17485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INR48_RS17495	COG0549	Belongs to the carbamate kinase family
INR48_RS17500	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
INR48_RS17500	COG3608	succinylglutamate desuccinylase aspartoacylase
INR48_RS17505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
INR48_RS17510	COG2068	MobA-Related Protein
INR48_RS17515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS17515	COG0493	'glutamate synthase
INR48_RS17520	COG0402	S-adenosylhomocysteine deaminase activity
INR48_RS17525	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
INR48_RS17530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
INR48_RS17530	COG2080	2 iron, 2 sulfur cluster binding
INR48_RS17535	COG2233	PERMEase
INR48_RS17540	COG0402	S-adenosylhomocysteine deaminase activity
INR48_RS17545	COG2252	PERMEase
INR48_RS17550	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS17560	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS17565	COG0493	'glutamate synthase
INR48_RS17565	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS17570	COG2233	PERMEase
INR48_RS17590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
INR48_RS17600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
INR48_RS17605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
INR48_RS17610	COG4974	Belongs to the 'phage' integrase family
INR48_RS17615	COG0716	FMN binding
INR48_RS17625	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
INR48_RS17635	COG1272	protein, Hemolysin III
INR48_RS17645	COG2723	6-phospho-beta-galactosidase activity
INR48_RS17650	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS17675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
INR48_RS17680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
INR48_RS17685	COG0006	proline dipeptidase activity
INR48_RS17705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
INR48_RS17715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
INR48_RS17735	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
INR48_RS17735	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
INR48_RS17740	COG1703	isobutyryl-CoA mutase activity
INR48_RS17745	COG1024	Enoyl-CoA hydratase
INR48_RS17750	COG0427	acetyl-CoA hydrolase
INR48_RS17755	COG0583	DNA-binding transcription factor activity
INR48_RS17760	COG2968	Membrane
INR48_RS17765	COG1279	arginine transmembrane transporter activity
INR48_RS17770	COG0668	transmembrane transport
INR48_RS17775	COG0191	fructose-bisphosphate aldolase activity
INR48_RS17790	COG1072	(Pantothenic acid kinase))
INR48_RS17795	COG3722	fumarate hydratase activity
INR48_RS17800	COG1494	fructose-1,6-bisphosphatase
INR48_RS17805	COG1063	alcohol dehydrogenase
INR48_RS17810	COG2213	PTS system mannitol-specific
INR48_RS17815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS17820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
INR48_RS17825	COG0501	Belongs to the peptidase M48B family
INR48_RS17835	COG1166	arginine decarboxylase activity
INR48_RS17855	COG2814	Major facilitator Superfamily
INR48_RS17865	COG2356	endonuclease I
INR48_RS17870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
INR48_RS17875	COG0189	ligase activity
INR48_RS17890	COG2805	Type II/IV secretion system protein
INR48_RS17895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
INR48_RS17900	COG0762	integral membrane protein
INR48_RS17915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INR48_RS17925	COG0252	asparaginase activity
INR48_RS17935	COG3171	Protein conserved in bacteria
INR48_RS17945	COG1194	a g-specific adenine glycosylase
INR48_RS17960	COG2211	Major facilitator Superfamily
INR48_RS17965	COG1982	Orn Lys Arg decarboxylase major
INR48_RS17970	COG1811	Na channel or pump
INR48_RS18000	COG4372	Transposase
INR48_RS18005	COG3436	PFAM IS66 Orf2 family protein
INR48_RS18060	COG3468	outer membrane autotransporter barrel domain protein
INR48_RS18080	COG2003	Belongs to the UPF0758 family
INR48_RS18115	COG2771	luxR family
INR48_RS18115	COG2200	EAL domain
INR48_RS18175	COG2089	acid synthase
INR48_RS18195	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
INR48_RS18225	COG2165	general secretion pathway protein
INR48_RS18230	COG1459	type II secretion system
INR48_RS18235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
INR48_RS18255	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
INR48_RS18260	COG3064	Membrane
INR48_RS18265	COG1620	l-lactate permease
INR48_RS18270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
INR48_RS18275	COG3193	protein, possibly involved in utilization of glycolate and propanediol
INR48_RS18280	COG0247	lactate metabolic process
INR48_RS18285	COG0277	FAD linked oxidase domain protein
INR48_RS18290	COG0277	FAD linked oxidase domain protein
INR48_RS18295	COG2186	Transcriptional regulator
INR48_RS18300	COG0456	acetyltransferase
INR48_RS18305	COG0318	PFAM AMP-dependent synthetase and ligase
INR48_RS18315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INR48_RS18320	COG0156	8-amino-7-oxononanoate synthase activity
INR48_RS18330	COG0795	lipopolysaccharide-transporting ATPase activity
INR48_RS18335	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
INR48_RS18345	COG2244	polysaccharide biosynthetic process
INR48_RS18350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
INR48_RS18355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
INR48_RS18360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
INR48_RS18365	COG0306	phosphate transporter
INR48_RS18370	COG0754	glutathionylspermidine amidase activity
INR48_RS18375	COG0625	glutathione transferase activity
INR48_RS18380	COG0298	carbon dioxide binding
INR48_RS18390	COG1773	rubredoxin
INR48_RS18395	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
INR48_RS18400	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
INR48_RS18405	COG5557	Pfam Polysulphide reductase, NrfD
INR48_RS18410	COG0437	4 iron, 4 sulfur cluster binding
INR48_RS18415	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
INR48_RS18430	COG0667	Aldo Keto reductase
INR48_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS18445	COG0848	biopolymer transport protein
INR48_RS18450	COG0811	peptide transport
INR48_RS18455	COG0626	cystathionine gamma-synthase activity
INR48_RS18460	COG0586	Pfam SNARE associated Golgi protein
INR48_RS18465	COG2207	Transcriptional regulator
INR48_RS18470	COG1979	alcohol dehydrogenase
INR48_RS18475	COG0656	L-ascorbic acid biosynthetic process
INR48_RS18485	COG4238	major outer membrane lipoprotein
INR48_RS18490	COG1032	radical SAM domain protein
INR48_RS18495	COG2132	Multicopper oxidase
INR48_RS18500	COG0204	Acyl-transferase
INR48_RS18505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
INR48_RS18510	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
INR48_RS18515	COG3111	PFAM Bacterial OB fold (BOF) protein
INR48_RS18520	COG0745	RESPONSE REGULATOR receiver
INR48_RS18525	COG0642	Histidine kinase
INR48_RS18530	COG2249	NAD(P)H dehydrogenase (quinone) activity
INR48_RS18535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
INR48_RS18540	COG1737	Transcriptional regulator
INR48_RS18550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INR48_RS18555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INR48_RS18560	COG1120	ATPase activity
INR48_RS18565	COG4774	siderophore transport
INR48_RS18570	COG0187	DNA topoisomerase II activity
INR48_RS18575	COG3150	esterase
INR48_RS18580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
INR48_RS18585	COG3151	Protein conserved in bacteria
INR48_RS18590	COG0494	nUDIX hydrolase
INR48_RS18595	COG1538	Outer membrane efflux protein
INR48_RS18605	COG0754	glutathionylspermidine amidase activity
INR48_RS18615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
INR48_RS18625	COG3384	dioxygenase
INR48_RS18655	COG1585	Membrane protein implicated in regulation of membrane protease activity
INR48_RS18660	COG2268	Band 7 protein
INR48_RS18685	COG3025	triphosphatase activity
INR48_RS18690	COG4991	sh3 domain protein
INR48_RS18705	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
INR48_RS18720	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
INR48_RS18725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
INR48_RS18740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
INR48_RS18745	COG0358	DNA primase activity
INR48_RS18750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INR48_RS18765	COG2375	cellular response to nickel ion
INR48_RS18770	COG1695	Transcriptional regulator
INR48_RS18775	COG0840	transmembrane signaling receptor activity
INR48_RS18785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INR48_RS18790	COG1609	Transcriptional regulator
INR48_RS18795	COG3250	beta-galactosidase activity
INR48_RS18800	COG2731	YhcH YjgK YiaL family protein
INR48_RS18805	COG0531	amino acid
INR48_RS18815	COG3408	Glycogen debranching enzyme
INR48_RS18815	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
INR48_RS18820	COG1902	pentaerythritol trinitrate reductase activity
INR48_RS18820	COG0446	pyridine nucleotide-disulphide oxidoreductase
INR48_RS18825	COG5499	transcription regulator containing HTH domain
INR48_RS18830	COG4680	protein conserved in bacteria
INR48_RS18840	COG1451	nucleotide metabolic process
INR48_RS18845	COG2949	membrane
INR48_RS18850	COG0673	inositol 2-dehydrogenase activity
INR48_RS18855	COG0861	Integral membrane protein TerC family
INR48_RS18860	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
INR48_RS18870	COG2721	sulfolactate sulfo-lyase activity
INR48_RS18880	COG2271	Major facilitator Superfamily
INR48_RS18885	COG2186	Transcriptional regulator
INR48_RS18890	COG0586	Pfam SNARE associated Golgi protein
INR48_RS18900	COG1422	Protein of unknown function (DUF1090)
INR48_RS18905	COG4575	ribosome binding
INR48_RS18910	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
INR48_RS18920	COG2259	Doxx family
INR48_RS18925	COG0435	Glutathione S-transferase
INR48_RS18930	COG3152	Membrane
INR48_RS18935	COG3152	Membrane
INR48_RS18940	COG0583	DNA-binding transcription factor activity
INR48_RS18945	COG1741	Belongs to the pirin family
INR48_RS18960	COG0814	amino acid
INR48_RS18965	COG1760	l-serine dehydratase
INR48_RS18970	COG0251	oxidation-reduction process
INR48_RS18975	COG1882	Formate acetyltransferase
INR48_RS18980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
INR48_RS18990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
INR48_RS18995	COG0583	DNA-binding transcription factor activity
INR48_RS19020	COG1929	Belongs to the glycerate kinase type-1 family
INR48_RS19025	COG2084	Dehydrogenase
INR48_RS19035	COG2271	Major facilitator Superfamily
INR48_RS19040	COG2721	sulfolactate sulfo-lyase activity
INR48_RS19045	COG2002	toxin-antitoxin pair type II binding
INR48_RS19055	COG1349	DNA-binding transcription factor activity
INR48_RS19065	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS19075	COG3716	PTS system mannose fructose sorbose family IID component
INR48_RS19080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS19085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
INR48_RS19090	COG2222	sugar isomerase
INR48_RS19100	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INR48_RS19105	COG3715	PTS system
INR48_RS19110	COG3716	PTS system mannose fructose sorbose family IID component
INR48_RS19115	COG0363	glucosamine-6-phosphate deaminase activity
INR48_RS19120	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
INR48_RS19140	COG2823	Periplasmic or secreted lipoprotein
INR48_RS19145	COG0701	Predicted permease
INR48_RS19150	COG0702	epimerase
INR48_RS19155	COG0693	protein deglycase activity
INR48_RS19170	COG3153	acetyltransferase
INR48_RS19175	COG3154	lipid carrier protein
INR48_RS19180	COG0826	peptidase U32
INR48_RS19185	COG0826	peptidase U32
INR48_RS19190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
INR48_RS19195	COG3034	peptidoglycan biosynthetic process
INR48_RS19205	COG0814	amino acid
INR48_RS19210	COG0513	Belongs to the DEAD box helicase family
INR48_RS19250	COG0195	Participates in both transcription termination and antitermination
INR48_RS19270	COG2194	sulfuric ester hydrolase activity
INR48_RS19280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
INR48_RS19290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
INR48_RS19295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
INR48_RS19305	COG1534	Rna-binding protein
INR48_RS19310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
INR48_RS19315	COG2027	D-alanyl-D-alanine carboxypeptidase
INR48_RS19325	COG0697	spore germination
INR48_RS19340	COG0142	geranyltranstransferase activity
INR48_RS19345	COG3423	Transcriptional regulator
INR48_RS19355	COG5007	Belongs to the BolA IbaG family
INR48_RS19360	COG3113	response to antibiotic
INR48_RS19365	COG2854	intermembrane phospholipid transfer
INR48_RS19370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
INR48_RS19375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
INR48_RS19380	COG1127	ABC transporter
INR48_RS19385	COG0530	calcium, potassium:sodium antiporter activity
INR48_RS19390	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
INR48_RS19390	COG0517	IMP dehydrogenase activity
INR48_RS19395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
INR48_RS19400	COG3117	lipopolysaccharide transmembrane transporter activity
INR48_RS19405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
INR48_RS19410	COG1137	ATPase activity
INR48_RS19415	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
INR48_RS19420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
INR48_RS19435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS19440	COG0515	serine threonine protein kinase
INR48_RS19450	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
INR48_RS19455	COG0784	Response regulator, receiver
INR48_RS19455	COG2198	Histidine kinase
INR48_RS19455	COG5002	protein histidine kinase activity
INR48_RS19460	COG1242	4 iron, 4 sulfur cluster binding
INR48_RS19465	COG0069	glutamate synthase activity
INR48_RS19465	COG0070	glutamate synthase
INR48_RS19465	COG0067	glutamate synthase
INR48_RS19470	COG0493	'glutamate synthase
INR48_RS19480	COG2731	YhcH YjgK YiaL family protein
INR48_RS19510	COG3069	C4-dicarboxylate transmembrane transporter activity
INR48_RS19515	COG2969	positive regulation of protein catabolic process
INR48_RS19520	COG0625	glutathione transferase activity
INR48_RS19535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
INR48_RS19540	COG3105	Protein conserved in bacteria
INR48_RS19545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INR48_RS19550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INR48_RS19570	COG2732	(Barnase) inhibitor
INR48_RS19590	COG0583	DNA-binding transcription factor activity
INR48_RS19595	COG0312	modulator of DNA gyrase
INR48_RS19600	COG3164	Protein of unknown function
INR48_RS19605	COG1530	ribonuclease E activity
INR48_RS19615	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
INR48_RS19620	COG1792	Involved in formation and maintenance of cell shape
INR48_RS19625	COG1077	Cell shape determining protein MreB Mrl
INR48_RS19630	COG2199	diguanylate cyclase activity
INR48_RS19630	COG2200	EAL domain
INR48_RS19635	COG0604	alcohol dehydrogenase
INR48_RS19645	COG0511	ligase activity, forming carbon-carbon bonds
INR48_RS19650	COG0439	Biotin carboxylase
INR48_RS19655	COG3924	membrane
INR48_RS19660	COG4145	pantothenate transmembrane transporter activity
INR48_RS19670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INR48_RS19680	COG2189	Belongs to the N(4) N(6)-methyltransferase family
INR48_RS19690	COG1309	transcriptional regulator
INR48_RS19695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INR48_RS19700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
INR48_RS19710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INR48_RS19715	COG4597	amino acid ABC transporter
INR48_RS19720	COG0765	amino acid transport
INR48_RS19725	COG1126	abc transporter atp-binding protein
INR48_RS19765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
INR48_RS19785	COG0551	DNA topoisomerase type I activity
INR48_RS19795	COG0758	DNA mediated transformation
INR48_RS19815	COG0569	domain protein
INR48_RS19825	COG3036	rescue of stalled ribosome
INR48_RS19830	COG0789	Transcriptional regulator
INR48_RS19870	COG0201	protein transport
INR48_RS19960	COG0089	rRNA binding
INR48_RS20030	COG2964	Protein conserved in bacteria
INR48_RS20035	COG0545	Peptidyl-prolyl cis-trans isomerase
INR48_RS20045	COG1047	Peptidyl-prolyl cis-trans
INR48_RS20050	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
INR48_RS20065	COG0488	(ABC) transporter
INR48_RS20070	COG0429	hydrolase of the alpha beta-hydrolase fold
INR48_RS20080	COG3954	Phosphoribulokinase
INR48_RS20085	COG1765	OsmC-like protein
INR48_RS20090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
INR48_RS20095	COG1289	transmembrane transporter activity
INR48_RS20100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
INR48_RS20105	COG0512	Glutamine amidotransferase of anthranilate synthase
INR48_RS20110	COG2184	nucleotidyltransferase activity
INR48_RS20120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
INR48_RS20130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
INR48_RS20135	COG2146	nitrite reductase [NAD(P)H] activity
INR48_RS20140	COG2116	formate transmembrane transporter activity
INR48_RS20155	COG0626	cystathionine gamma-synthase activity
INR48_RS20170	COG1735	metal-dependent hydrolase with the TIM-barrel fold
INR48_RS20175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
INR48_RS20180	COG3457	Alanine racemase
INR48_RS20190	COG2188	Transcriptional regulator
INR48_RS20195	COG0180	Tryptophanyl-tRNA synthetase
INR48_RS20205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
INR48_RS20210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
INR48_RS20215	COG3266	domain, Protein
INR48_RS20230	COG4796	Type ii and iii secretion system protein
INR48_RS20245	COG3166	PFAM Fimbrial assembly family protein
INR48_RS20250	COG4972	Pilus assembly protein
INR48_RS20255	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
INR48_RS20260	COG0494	nUDIX hydrolase
INR48_RS20270	COG1011	Hydrolase
INR48_RS20275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
INR48_RS20285	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
INR48_RS20305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
INR48_RS20310	COG2183	response to ionizing radiation
INR48_RS20315	COG1918	ferrous iron import across plasma membrane
INR48_RS20320	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
INR48_RS20330	COG5464	transposase or invertase
INR48_RS20350	COG2610	gluconate transmembrane transporter activity
INR48_RS20355	COG1640	4-alpha-glucanotransferase
INR48_RS20360	COG0058	SHG alpha-glucan phosphorylase activity
INR48_RS20380	COG4650	regulator
INR48_RS20385	COG1349	DNA-binding transcription factor activity
INR48_RS20400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
INR48_RS20410	COG3121	Chaperone
INR48_RS20420	COG3539	Fimbrial protein
INR48_RS20425	COG3188	usher protein
INR48_RS20430	COG3121	Chaperone
INR48_RS20440	COG0058	SHG alpha-glucan phosphorylase activity
INR48_RS20460	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
INR48_RS20465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
INR48_RS20470	COG2095	MarC family integral membrane protein
INR48_RS20475	COG2610	gluconate transmembrane transporter activity
INR48_RS20480	COG3265	gluconokinase activity
INR48_RS20485	COG1609	Transcriptional regulator
INR48_RS20490	COG1741	Belongs to the pirin family
INR48_RS20495	COG0673	inositol 2-dehydrogenase activity
INR48_RS20500	COG1247	-acetyltransferase
INR48_RS20505	COG3157	Type VI secretion system effector, Hcp
INR48_RS20525	COG0405	Gamma-glutamyltransferase
INR48_RS20535	COG0584	glycerophosphoryl diester phosphodiesterase
INR48_RS20550	COG1175	transmembrane transport
INR48_RS20555	COG1653	transport
INR48_RS20560	COG0410	ABC transporter
INR48_RS20565	COG0411	ABC transporter
INR48_RS20570	COG4177	L-phenylalanine transmembrane transporter activity
INR48_RS20575	COG0559	Belongs to the binding-protein-dependent transport system permease family
INR48_RS20580	COG0683	leucine binding
INR48_RS20585	COG0456	acetyltransferase
INR48_RS20595	COG0683	leucine binding
INR48_RS20600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INR48_RS20605	COG2177	Part of the ABC transporter FtsEX involved in
INR48_RS20610	COG2884	Cell division ATP-binding protein ftsE
INR48_RS20615	COG0552	protein localization to endoplasmic reticulum
INR48_RS20620	COG0742	ribosomal rna small subunit methyltransferase
INR48_RS20625	COG3776	membrane
INR48_RS20635	COG3714	YhhN family
INR48_RS20655	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
INR48_RS20665	COG0477	Major facilitator Superfamily
INR48_RS20670	COG0628	permease
INR48_RS20690	COG0204	Acyl-transferase
INR48_RS20700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INR48_RS20720	COG1216	Glycosyl transferase, family 2
INR48_RS20745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INR48_RS20755	COG1028	Short-chain dehydrogenase reductase Sdr
INR48_RS20760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INR48_RS20765	COG2091	lysine biosynthetic process via aminoadipic acid
INR48_RS20770	COG0747	negative chemotaxis
INR48_RS20775	COG0601	transmembrane transport
INR48_RS20780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INR48_RS20800	COG2188	Transcriptional regulator
INR48_RS20810	COG3414	Phosphotransferase system galactitol-specific IIB component
INR48_RS20815	COG3775	system Galactitol-specific IIC component
INR48_RS20830	COG0191	fructose-bisphosphate aldolase activity
INR48_RS20835	COG0842	Transport permease protein
INR48_RS20840	COG1129	ABC transporter
INR48_RS20840	COG0842	Transport permease protein
INR48_RS20845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INR48_RS20865	COG2081	HI0933 family
INR48_RS20870	COG0306	phosphate transporter
INR48_RS20880	COG0589	response to stress
INR48_RS20885	COG3104	oligopeptide transport
INR48_RS20895	COG0339	signal peptide processing
INR48_RS20900	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
INR48_RS20905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INR48_RS20920	COG0640	Transcriptional regulator
INR48_RS20935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
INR48_RS20940	COG1393	Belongs to the ArsC family
INR48_RS20960	COG3065	identical protein binding
INR48_RS20965	COG2197	response regulator
INR48_RS20970	COG3720	iron ion transport
INR48_RS20975	COG4771	TonB-dependent receptor
INR48_RS20980	COG4558	Periplasmic binding protein
INR48_RS20990	COG3721	Heme iron utilization protein
INR48_RS21000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INR48_RS21010	COG1285	pathogenesis
INR48_RS21025	COG3247	response to pH
INR48_RS21030	COG2771	luxR family
INR48_RS21040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INR48_RS21045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
INR48_RS21050	COG2207	Transcriptional regulator
INR48_RS21055	COG2207	Transcriptional regulator
INR48_RS21060	COG0076	glutamate decarboxylase activity
INR48_RS21065	COG1858	cytochrome C peroxidase
INR48_RS21075	COG2197	response regulator
INR48_RS21080	COG0583	DNA-binding transcription factor activity
INR48_RS21085	COG1295	ribonuclease BN
INR48_RS21090	COG0477	Major facilitator Superfamily
INR48_RS21095	COG2982	Protein involved in outer membrane biogenesis
INR48_RS21100	COG2200	EAL domain
INR48_RS21135	COG0612	Peptidase, M16
INR48_RS21145	COG2199	diguanylate cyclase activity
INR48_RS21145	COG2200	EAL domain
INR48_RS21150	COG0457	Tetratricopeptide repeat
INR48_RS21150	COG3118	belongs to the thioredoxin family
INR48_RS21155	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
INR48_RS21160	COG1215	transferase activity, transferring glycosyl groups
INR48_RS21165	COG1215	transferase activity, transferring glycosyl groups
INR48_RS21190	COG2194	sulfuric ester hydrolase activity
INR48_RS21205	COG0814	amino acid
INR48_RS21210	COG4608	Belongs to the ABC transporter superfamily
INR48_RS21215	COG0444	Belongs to the ABC transporter superfamily
INR48_RS21220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INR48_RS21225	COG0601	transmembrane transport
INR48_RS21230	COG0747	negative chemotaxis
INR48_RS21245	COG2194	sulfuric ester hydrolase activity
INR48_RS21250	COG2223	nitrite transmembrane transporter activity
INR48_RS21255	COG5571	outer membrane autotransporter
INR48_RS21260	COG2818	Glycosylase
INR48_RS21265	COG0456	acetyltransferase
INR48_RS21270	COG0243	molybdopterin cofactor binding
INR48_RS21275	COG2885	chlorophyll binding
INR48_RS21290	COG2944	sequence-specific DNA binding
INR48_RS21295	COG1278	Cold shock
INR48_RS21320	COG3274	enterobacterial common antigen metabolic process
INR48_RS21325	COG4682	membrane
INR48_RS21330	COG4682	membrane
INR48_RS21335	COG1070	Carbohydrate kinase
INR48_RS21345	COG4213	ABC transporter substrate-binding protein
INR48_RS21355	COG4214	carbohydrate transport
INR48_RS21360	COG1609	Transcriptional regulator
INR48_RS21360	COG2207	Transcriptional regulator
INR48_RS21365	COG2992	FlgJ-related protein
INR48_RS21370	COG0366	Alpha amylase catalytic
INR48_RS21375	COG3977	Valine--pyruvate aminotransferase
INR48_RS21380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
INR48_RS21385	COG1414	Transcriptional regulator
INR48_RS21395	COG2731	YhcH YjgK YiaL family protein
INR48_RS21400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
INR48_RS21405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
INR48_RS21410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
INR48_RS21415	COG1070	Carbohydrate kinase
INR48_RS21420	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
INR48_RS21425	COG3623	hexulose-6-phosphate isomerase
INR48_RS21430	COG0235	Class ii aldolase
INR48_RS21440	COG2211	Major facilitator Superfamily
INR48_RS21450	COG1598	PFAM Uncharacterised protein family UPF0150
INR48_RS21460	COG1012	belongs to the aldehyde dehydrogenase family
INR48_RS21465	COG1454	alcohol dehydrogenase
INR48_RS21470	COG3276	selenocysteine insertion sequence binding
INR48_RS21480	COG0625	glutathione transferase activity
INR48_RS21485	COG1566	PFAM secretion protein HlyD family protein
INR48_RS21495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
INR48_RS21495	COG2213	PTS system mannitol-specific
INR48_RS21505	COG3722	fumarate hydratase activity
INR48_RS21525	COG5295	Hep Hag repeat protein
INR48_RS21530	COG1620	l-lactate permease
INR48_RS21535	COG2186	Transcriptional regulator
INR48_RS21545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
INR48_RS21555	COG1045	serine acetyltransferase
INR48_RS21570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
INR48_RS21575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
INR48_RS21585	COG4942	peptidase
INR48_RS21590	COG2861	carbohydrate metabolic process
INR48_RS21595	COG1216	Glycosyl transferase, family 2
INR48_RS21605	COG0156	8-amino-7-oxononanoate synthase activity
INR48_RS21620	COG0859	PFAM glycosyl transferase family 9
INR48_RS21625	COG0859	PFAM glycosyl transferase family 9
INR48_RS21645	COG3642	lipopolysaccharide core region biosynthetic process
INR48_RS21655	COG0515	serine threonine protein kinase
INR48_RS21660	COG0438	transferase activity, transferring glycosyl groups
INR48_RS21665	COG0859	PFAM glycosyl transferase family 9
INR48_RS21670	COG1519	Transferase
INR48_RS21700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
INR48_RS21725	COG1561	YicC-like family, N-terminal region
INR48_RS21730	COG3645	SOS response
INR48_RS21735	COG2860	membrane
INR48_RS21745	COG0194	GDP metabolic process
INR48_RS21755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INR48_RS21760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INR48_RS21765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
INR48_RS21770	COG0786	glutamate:sodium symporter activity
INR48_RS21775	COG2233	PERMEase
INR48_RS21780	COG2982	Protein involved in outer membrane biogenesis
INR48_RS21785	COG1501	Belongs to the glycosyl hydrolase 31 family
INR48_RS21790	COG2211	Major facilitator Superfamily
INR48_RS21805	COG2814	Major facilitator Superfamily
INR48_RS21810	COG0697	spore germination
INR48_RS21815	COG1464	Belongs to the NlpA lipoprotein family
INR48_RS21825	COG0457	Tetratricopeptide repeat
INR48_RS21850	COG1388	LysM domain
INR48_RS21850	COG2373	Large extracellular alpha-helical protein
INR48_RS21850	COG4932	domain protein
INR48_RS21875	COG2252	PERMEase
INR48_RS21890	COG2271	Major facilitator Superfamily
INR48_RS21895	COG2271	Major facilitator Superfamily
INR48_RS21900	COG3851	Histidine kinase
INR48_RS21905	COG2197	response regulator
INR48_RS21920	COG0440	acetolactate synthase activity
INR48_RS21925	COG0028	Belongs to the TPP enzyme family
INR48_RS21940	COG2814	Major facilitator Superfamily
INR48_RS21945	COG0641	radical SAM
INR48_RS21955	COG2149	membrane
INR48_RS21965	COG3119	arylsulfatase activity
INR48_RS21975	COG2207	Transcriptional regulator
INR48_RS21990	COG2188	Transcriptional regulator
INR48_RS22010	COG5645	(Lipo)protein
INR48_RS22015	COG0823	Involved in the tonB-independent uptake of proteins
INR48_RS22025	COG2271	Major facilitator Superfamily
INR48_RS22035	COG0800	Aldolase
INR48_RS22040	COG3734	2-keto-3-deoxy-galactonokinase
INR48_RS22045	COG2186	Transcriptional regulator
INR48_RS22055	COG0561	phosphatase activity
INR48_RS22060	COG3753	Protein conserved in bacteria
INR48_RS22065	COG0187	DNA topoisomerase II activity
INR48_RS22075	COG0592	DNA-directed DNA polymerase activity
INR48_RS22125	COG0814	amino acid
INR48_RS22140	COG2091	lysine biosynthetic process via aminoadipic acid
INR48_RS22145	COG0431	NADPH-dependent FMN reductase
INR48_RS22150	COG2252	PERMEase
INR48_RS22155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
INR48_RS22175	COG0704	Plays a role in the regulation of phosphate uptake
INR48_RS22180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
INR48_RS22185	COG0581	inorganic phosphate transmembrane transporter activity
INR48_RS22190	COG0573	inorganic phosphate transmembrane transporter activity
INR48_RS22195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
INR48_RS22215	COG3539	Fimbrial protein
INR48_RS22270	COG3312	ion transport
INR48_RS22285	COG0716	FMN binding
INR48_RS22290	COG1522	sequence-specific DNA binding
INR48_RS22320	COG1129	ABC transporter
INR48_RS22325	COG1172	Belongs to the binding-protein-dependent transport system permease family
INR48_RS22330	COG1879	ABC-type sugar transport system periplasmic component
INR48_RS22335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INR48_RS22340	COG1609	Transcriptional regulator
INR48_RS22345	COG0477	Major facilitator Superfamily
INR48_RS22350	COG2186	Transcriptional regulator
INR48_RS22390	COG3085	chromosome segregation
INR48_RS22395	COG0606	chelatase, subunit chli
INR48_RS22415	COG3978	acetolactate synthase activity
INR48_RS22420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
INR48_RS22430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
INR48_RS22435	COG0583	DNA-binding transcription factor activity
INR48_RS22445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INR48_RS22450	COG0210	DNA helicase
INR48_RS22465	COG3118	belongs to the thioredoxin family
INR48_RS22475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
INR48_RS22480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
INR48_RS22485	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
INR48_RS22490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
INR48_RS22495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
INR48_RS22500	COG1088	dTDP-glucose 4,6-dehydratase activity
INR48_RS22505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
INR48_RS22510	COG0456	acetyltransferase
INR48_RS22515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
INR48_RS22520	COG2244	polysaccharide biosynthetic process
INR48_RS22540	COG1113	amino acid transport
INR48_RS22565	COG0641	radical SAM
INR48_RS22575	COG3119	arylsulfatase activity
INR48_RS22580	COG3071	HemY protein
INR48_RS22585	COG2959	enzyme of heme biosynthesis
INR48_RS22590	COG1587	Uroporphyrinogen-III synthase
INR48_RS22600	COG3072	Adenylate cyclase
INR48_RS22615	COG5567	small periplasmic lipoprotein
INR48_RS22625	COG3159	Protein conserved in bacteria
INR48_RS22635	COG1011	Hydrolase
INR48_RS22640	COG0210	DNA helicase
INR48_RS22650	COG3698	Phosphodiester glycosidase
INR48_RS22655	COG0598	Magnesium transport protein CorA
INR48_RS22670	COG2962	Rard protein
INR48_RS22675	COG2050	protein possibly involved in aromatic compounds catabolism
INR48_RS22680	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
INR48_RS22685	COG0514	ATP-dependent DNA helicase (RecQ)
INR48_RS22690	COG1280	lysine exporter protein (LysE YggA)
INR48_RS22695	COG1280	lysine exporter protein (LysE YggA)
INR48_RS22700	COG2267	carboxylic ester hydrolase activity
INR48_RS22705	COG0561	phosphatase activity
INR48_RS22710	COG0697	spore germination
INR48_RS22715	COG0583	DNA-binding transcription factor activity
INR48_RS22725	COG0412	Dienelactone hydrolase
INR48_RS22730	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
INR48_RS22735	COG1322	Protein conserved in bacteria
INR48_RS22745	COG3165	ubiquinone biosynthetic process from chorismate
INR48_RS22755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
INR48_RS22760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
INR48_RS22765	COG0805	protein transport
INR48_RS22775	COG0250	Participates in transcription elongation, termination and antitermination
INR48_RS22780	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
INR48_RS22785	COG0543	2 iron, 2 sulfur cluster binding
INR48_RS22790	COG0183	Belongs to the thiolase family
INR48_RS22805	COG1739	Uncharacterized protein family UPF0029
INR48_RS22810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
INR48_RS22815	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
INR48_RS22845	COG1763	Mo-molybdopterin cofactor biosynthetic process
INR48_RS22850	COG0746	molybdenum cofactor guanylyltransferase activity
INR48_RS22855	COG3084	Protein conserved in bacteria
INR48_RS22860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
INR48_RS22865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
INR48_RS22870	COG5339	Protein conserved in bacteria
INR48_RS22875	COG0204	Acyl-transferase
INR48_RS22880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INR48_RS22880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INR48_RS22895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INR48_RS22905	COG2204	response regulator
INR48_RS22910	COG3852	Histidine kinase
INR48_RS22915	COG0174	glutamine synthetase
INR48_RS22920	COG1217	gtp-binding protein TYPA
INR48_RS22925	COG2188	Transcriptional regulator
INR48_RS22945	COG2271	Major facilitator Superfamily
INR48_RS22950	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
INR48_RS22955	COG2211	Major facilitator Superfamily
INR48_RS22960	COG2211	Major facilitator Superfamily
INR48_RS22965	COG1501	Belongs to the glycosyl hydrolase 31 family
INR48_RS22970	COG2017	converts alpha-aldose to the beta-anomer
INR48_RS22975	COG2942	2-epimerase
INR48_RS22980	COG3684	Belongs to the aldolase LacD family
INR48_RS22985	COG2084	Dehydrogenase
INR48_RS22990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INR48_RS22995	COG1349	DNA-binding transcription factor activity
INR48_RS23000	COG1011	Hydrolase
INR48_RS23015	COG0456	acetyltransferase
INR48_RS23025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
INR48_RS23030	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
INR48_RS23040	COG2864	formate dehydrogenase
INR48_RS23045	COG0437	4 iron, 4 sulfur cluster binding
INR48_RS23095	COG4977	sequence-specific DNA binding
INR48_RS23095	COG1917	Cupin 2, conserved barrel domain protein
INR48_RS23105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
INR48_RS23115	COG2258	MOSC domain
INR48_RS23120	COG2205	protein histidine kinase activity
INR48_RS23125	COG0745	RESPONSE REGULATOR receiver
INR48_RS23130	COG3678	ATP-independent chaperone mediated protein folding
INR48_RS23145	COG4974	Belongs to the 'phage' integrase family
INR48_RS23195	COG2207	Transcriptional regulator
INR48_RS23195	COG3708	Transcriptional regulator
INR48_RS23230	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
INR48_RS23245	COG3436	PFAM IS66 Orf2 family protein
INR48_RS23610	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
INR48_RS23625	COG3436	PFAM IS66 Orf2 family protein
INR48_RS23665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
INR48_RS23670	COG1459	type II secretion system
INR48_RS23675	COG2165	general secretion pathway protein
INR48_RS23705	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
INR48_RS23760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
INR48_RS23815	COG2819	hydrolase of the alpha beta superfamily
INR48_RS23830	COG1620	l-lactate permease
INR48_RS23835	COG2186	Transcriptional regulator
INR48_RS23850	COG2826	transposase and inactivated derivatives, IS30 family
INR48_RS23875	COG2826	transposase and inactivated derivatives, IS30 family
INR48_RS23905	COG0629	single-stranded DNA binding
INR48_RS23960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
INR48_RS24020	COG0741	lytic transglycosylase activity
INR48_RS24155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
INR48_RS24185	COG0305	Participates in initiation and elongation during chromosome replication
INR48_RS24360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
INR48_RS24470	COG0675	Transposase, IS605 OrfB family
INR48_RS24610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INR48_RS24680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
INR48_RS24700	COG2274	protein secretion by the type I secretion system
INR48_RS24700	COG3271	cysteine-type peptidase activity
INR48_RS24710	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
INR48_RS24730	COG3451	type IV secretory pathway VirB4
INR48_RS24825	COG0330	HflC and HflK could