locus-tag	class	description
MS6198_RS00010	COG0527	aspartate kinase activity
MS6198_RS00010	COG0460	homoserine dehydrogenase
MS6198_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MS6198_RS00040	COG1115	amino acid carrier protein
MS6198_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
MS6198_RS00055	COG1584	GPR1 FUN34 yaaH family protein
MS6198_RS00060	COG4735	regulation of single-species biofilm formation
MS6198_RS00105	COG0583	DNA-binding transcription factor activity
MS6198_RS00115	COG3188	usher protein
MS6198_RS00120	COG3121	Chaperone
MS6198_RS00145	COG0196	riboflavin kinase activity
MS6198_RS00160	COG1047	Peptidyl-prolyl cis-trans
MS6198_RS00190	COG0505	Belongs to the CarA family
MS6198_RS00195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MS6198_RS00250	COG0644	oxidoreductase
MS6198_RS00255	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MS6198_RS00260	COG2271	Major facilitator Superfamily
MS6198_RS00270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MS6198_RS00270	COG0475	glutathione-regulated potassium exporter activity
MS6198_RS00275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MS6198_RS00310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MS6198_RS00315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MS6198_RS00320	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MS6198_RS00325	COG1357	PFAM Pentapeptide repeats (8 copies)
MS6198_RS00330	COG0564	pseudouridine synthase activity
MS6198_RS00340	COG0417	DNA replication proofreading
MS6198_RS00345	COG0235	Class ii aldolase
MS6198_RS00360	COG4977	sequence-specific DNA binding
MS6198_RS00365	COG0586	Pfam SNARE associated Golgi protein
MS6198_RS00375	COG1178	ABC-type Fe3 transport system permease component
MS6198_RS00380	COG4143	(ABC) transporter
MS6198_RS00425	COG0583	DNA-binding transcription factor activity
MS6198_RS00430	COG0028	Belongs to the TPP enzyme family
MS6198_RS00435	COG0440	acetolactate synthase activity
MS6198_RS00445	COG1609	Transcriptional regulator
MS6198_RS00460	COG3116	cell division
MS6198_RS00465	COG0768	penicillin binding
MS6198_RS00470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MS6198_RS00475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MS6198_RS00490	COG0772	Belongs to the SEDS family
MS6198_RS00505	COG1181	Belongs to the D-alanine--D-alanine ligase family
MS6198_RS00510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MS6198_RS00515	COG0849	cell division
MS6198_RS00520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MS6198_RS00540	COG0494	nUDIX hydrolase
MS6198_RS00560	COG0237	dephospho-CoA kinase activity
MS6198_RS00570	COG1459	type II secretion system
MS6198_RS00575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MS6198_RS00580	COG4969	Belongs to the N-Me-Phe pilin family
MS6198_RS00590	COG0157	Belongs to the NadC ModD family
MS6198_RS00595	COG3023	N-Acetylmuramoyl-L-alanine amidase
MS6198_RS00600	COG3725	Membrane protein required for beta-lactamase induction
MS6198_RS00605	COG1113	amino acid transport
MS6198_RS00610	COG2186	Transcriptional regulator
MS6198_RS00615	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MS6198_RS00620	COG0508	dehydrogenase complex catalyzes the overall conversion of
MS6198_RS00625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS6198_RS00630	COG3064	Membrane
MS6198_RS00635	COG1049	propionate catabolic process, 2-methylcitrate cycle
MS6198_RS00660	COG2132	Multicopper oxidase
MS6198_RS00665	COG4993	Dehydrogenase
MS6198_RS00670	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MS6198_RS00675	COG0288	reversible hydration of carbon dioxide
MS6198_RS00680	COG1131	(ABC) transporter
MS6198_RS00685	COG0842	Transport permease protein
MS6198_RS00690	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS00695	COG0726	polysaccharide deacetylase
MS6198_RS00705	COG5464	transposase or invertase
MS6198_RS00725	COG3539	Fimbrial protein
MS6198_RS00730	COG3539	Fimbrial protein
MS6198_RS00735	COG3539	Fimbrial protein
MS6198_RS00740	COG3539	Fimbrial protein
MS6198_RS00745	COG3188	usher protein
MS6198_RS00750	COG3121	Chaperone
MS6198_RS00755	COG3539	Fimbrial protein
MS6198_RS00760	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MS6198_RS00765	COG0617	tRNA 3'-terminal CCA addition
MS6198_RS00770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MS6198_RS00775	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MS6198_RS00785	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MS6198_RS00790	COG1643	Atp-dependent helicase
MS6198_RS00795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MS6198_RS00800	COG4774	siderophore transport
MS6198_RS00805	COG1120	ATPase activity
MS6198_RS00810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MS6198_RS00815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS6198_RS00835	COG2860	membrane
MS6198_RS00840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MS6198_RS00855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MS6198_RS00860	COG3835	regulator
MS6198_RS00870	COG1408	metallophosphoesterase
MS6198_RS00885	COG0024	Methionine aminopeptidase
MS6198_RS00910	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MS6198_RS00915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MS6198_RS00920	COG0575	Belongs to the CDS family
MS6198_RS00925	COG0750	zinc metalloprotease
MS6198_RS00935	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
MS6198_RS00940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MS6198_RS00965	COG0587	DNA-directed DNA polymerase activity
MS6198_RS00975	COG1982	Orn Lys Arg decarboxylase major
MS6198_RS00980	COG0346	lactoylglutathione lyase activity
MS6198_RS00985	COG0037	tRNA processing
MS6198_RS00990	COG4568	rho-dependent transcription termination
MS6198_RS01000	COG4681	YaeQ
MS6198_RS01005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MS6198_RS01010	COG3015	lipoprotein NlpE involved in copper resistance
MS6198_RS01015	COG0791	NLP P60 protein
MS6198_RS01025	COG1720	tRNA m6t6A37 methyltransferase activity
MS6198_RS01035	COG1464	Belongs to the NlpA lipoprotein family
MS6198_RS01040	COG2011	ABC-type metal ion transport system permease component
MS6198_RS01050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MS6198_RS01085	COG0656	L-ascorbic acid biosynthetic process
MS6198_RS01090	COG0583	DNA-binding transcription factor activity
MS6198_RS01100	COG2226	methyltransferase
MS6198_RS01105	COG0741	lytic transglycosylase activity
MS6198_RS01105	COG1388	LysM domain
MS6198_RS01115	COG2226	methyltransferase
MS6198_RS01125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MS6198_RS01145	COG4104	PAAR repeat-containing protein
MS6198_RS01150	COG3157	Type VI secretion system effector, Hcp
MS6198_RS01255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MS6198_RS01265	COG1960	acyl-CoA dehydrogenase activity
MS6198_RS01275	COG0121	glutamine amidotransferase
MS6198_RS01280	COG3034	peptidoglycan biosynthetic process
MS6198_RS01290	COG3077	Addiction module antitoxin, RelB DinJ family
MS6198_RS01295	COG0791	NLP P60 protein
MS6198_RS01315	COG2161	toxin-antitoxin pair type II binding
MS6198_RS01325	COG0454	-acetyltransferase
MS6198_RS01330	COG1690	Belongs to the RtcB family
MS6198_RS01335	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MS6198_RS01350	COG2195	Cleaves the N-terminal amino acid of tripeptides
MS6198_RS01370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MS6198_RS01395	COG3477	response to acidic pH
MS6198_RS01400	COG0727	PFAM Uncharacterised protein family (UPF0153)
MS6198_RS01450	COG1902	pentaerythritol trinitrate reductase activity
MS6198_RS01455	COG1073	alpha beta
MS6198_RS01460	COG0583	DNA-binding transcription factor activity
MS6198_RS01470	COG0667	Aldo Keto reductase
MS6198_RS01475	COG0656	L-ascorbic acid biosynthetic process
MS6198_RS01480	COG1388	LysM domain
MS6198_RS01485	COG2207	Transcriptional regulator
MS6198_RS01485	COG3708	Transcriptional regulator
MS6198_RS01490	COG0656	L-ascorbic acid biosynthetic process
MS6198_RS01495	COG3059	membrane
MS6198_RS01505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS6198_RS01510	COG2207	Transcriptional regulator
MS6198_RS01515	COG0247	lactate metabolic process
MS6198_RS01520	COG1139	Iron-sulfur cluster binding protein
MS6198_RS01525	COG1556	Lactate utilization protein
MS6198_RS01550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS6198_RS01560	COG2200	EAL domain
MS6198_RS01560	COG2771	luxR family
MS6198_RS01565	COG0583	DNA-binding transcription factor activity
MS6198_RS01575	COG0666	response to abiotic stimulus
MS6198_RS01585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MS6198_RS01590	COG1304	FMN binding
MS6198_RS01595	COG0549	Belongs to the carbamate kinase family
MS6198_RS01600	COG0402	S-adenosylhomocysteine deaminase activity
MS6198_RS01610	COG1064	alcohol dehydrogenase
MS6198_RS01625	COG1280	lysine exporter protein (LysE YggA)
MS6198_RS01635	COG3829	transcription factor binding
MS6198_RS01640	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MS6198_RS01645	COG0372	Belongs to the citrate synthase family
MS6198_RS01650	COG2079	MmgE PrpD family protein
MS6198_RS01655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MS6198_RS01660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MS6198_RS01665	COG0402	S-adenosylhomocysteine deaminase activity
MS6198_RS01670	COG0583	DNA-binding transcription factor activity
MS6198_RS01675	COG0288	reversible hydration of carbon dioxide
MS6198_RS01685	COG2807	transmembrane transport
MS6198_RS01690	COG0110	maltose O-acetyltransferase activity
MS6198_RS01695	COG2223	nitrite transmembrane transporter activity
MS6198_RS01705	COG1609	Transcriptional regulator
MS6198_RS01710	COG1414	Transcriptional regulator
MS6198_RS01745	COG2814	Major facilitator Superfamily
MS6198_RS01750	COG3122	Protein conserved in bacteria
MS6198_RS01780	COG1215	transferase activity, transferring glycosyl groups
MS6198_RS01785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MS6198_RS01790	COG4521	taurine ABC transporter
MS6198_RS01800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MS6198_RS01805	COG2175	clavaminate synthase activity
MS6198_RS01810	COG0113	porphobilinogen synthase activity
MS6198_RS01815	COG3468	outer membrane autotransporter barrel domain protein
MS6198_RS01820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MS6198_RS01825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MS6198_RS01835	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MS6198_RS01855	COG1181	Belongs to the D-alanine--D-alanine ligase family
MS6198_RS01870	COG1785	Belongs to the alkaline phosphatase family
MS6198_RS01880	COG3706	GGDEF domain
MS6198_RS01885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MS6198_RS01910	COG4126	flavin adenine dinucleotide binding
MS6198_RS01930	COG1940	carbohydrate kinase activity
MS6198_RS01935	COG2814	Major facilitator Superfamily
MS6198_RS01940	COG0419	ATPase involved in DNA repair
MS6198_RS01945	COG0420	3'-5' exonuclease activity
MS6198_RS01950	COG0745	RESPONSE REGULATOR receiver
MS6198_RS01955	COG5002	protein histidine kinase activity
MS6198_RS01960	COG1114	Component of the transport system for branched-chain amino acids
MS6198_RS01965	COG1113	amino acid transport
MS6198_RS01970	COG0366	Alpha amylase catalytic
MS6198_RS01995	COG1862	Preprotein translocase
MS6198_RS02000	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MS6198_RS02005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MS6198_RS02010	COG1403	HNH endonuclease
MS6198_RS02015	COG3248	Nucleoside-binding outer membrane protein
MS6198_RS02020	COG4238	major outer membrane lipoprotein
MS6198_RS02030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MS6198_RS02030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MS6198_RS02045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MS6198_RS02050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MS6198_RS02055	COG0667	Aldo Keto reductase
MS6198_RS02065	COG0142	geranyltranstransferase activity
MS6198_RS02080	COG0693	protein deglycase activity
MS6198_RS02085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MS6198_RS02095	COG2814	Major facilitator Superfamily
MS6198_RS02105	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MS6198_RS02110	COG1845	cytochrome c oxidase, subunit III
MS6198_RS02115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MS6198_RS02120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MS6198_RS02125	COG2223	nitrite transmembrane transporter activity
MS6198_RS02130	COG3056	Lipoprotein
MS6198_RS02135	COG0271	Belongs to the BolA IbaG family
MS6198_RS02160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MS6198_RS02165	COG0776	regulation of translation
MS6198_RS02170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MS6198_RS02175	COG1555	photosystem II stabilization
MS6198_RS02180	COG0824	Thioesterase
MS6198_RS02190	COG4533	DNA binding
MS6198_RS02200	COG1522	sequence-specific DNA binding
MS6198_RS02205	COG1132	(ABC) transporter
MS6198_RS02210	COG1132	(ABC) transporter
MS6198_RS02215	COG0347	Belongs to the P(II) protein family
MS6198_RS02220	COG0004	ammonium transporteR
MS6198_RS02225	COG1946	Acyl-CoA thioesterase
MS6198_RS02230	COG3126	Type III secretion system lipoprotein chaperone (YscW)
MS6198_RS02235	COG3695	enzyme binding
MS6198_RS02245	COG5507	3-demethylubiquinone-9 3-methyltransferase
MS6198_RS02250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MS6198_RS02260	COG0110	maltose O-acetyltransferase activity
MS6198_RS02275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS6198_RS02280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS6198_RS02285	COG1309	transcriptional regulator
MS6198_RS02290	COG1196	nuclear chromosome segregation
MS6198_RS02290	COG3264	Mechanosensitive ion channel
MS6198_RS02300	COG3923	Primosomal replication protein n
MS6198_RS02305	COG2832	Protein of unknown function (DUF454)
MS6198_RS02315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MS6198_RS02350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS02355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MS6198_RS02355	COG4651	solute:proton antiporter activity
MS6198_RS02360	COG2223	nitrite transmembrane transporter activity
MS6198_RS02365	COG0737	Belongs to the 5'-nucleotidase family
MS6198_RS02370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MS6198_RS02375	COG3735	TraB family
MS6198_RS02380	COG3549	Plasmid maintenance system killer
MS6198_RS02385	COG3093	addiction module antidote protein HigA
MS6198_RS02390	COG2217	Heavy metal translocating P-type atpase
MS6198_RS02400	COG0531	amino acid
MS6198_RS02405	COG0789	Transcriptional regulator
MS6198_RS02430	COG1585	Membrane protein implicated in regulation of membrane protease activity
MS6198_RS02435	COG0330	HflC and HflK could
MS6198_RS02440	COG4619	ABC transporter
MS6198_RS02445	COG0390	transport system, permease component
MS6198_RS02450	COG3118	belongs to the thioredoxin family
MS6198_RS02455	COG0300	oxidoreductase activity
MS6198_RS02460	COG2755	lipolytic protein G-D-S-L family
MS6198_RS02465	COG4181	ATPase activity
MS6198_RS02470	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MS6198_RS02485	COG0583	DNA-binding transcription factor activity
MS6198_RS02495	COG1414	Transcriptional regulator
MS6198_RS02500	COG3960	tartronate-semialdehyde synthase activity
MS6198_RS02505	COG3622	Belongs to the hyi family
MS6198_RS02510	COG2084	Dehydrogenase
MS6198_RS02515	COG1953	Uracil, thiamine, allantoin
MS6198_RS02525	COG2233	PERMEase
MS6198_RS02530	COG1929	Belongs to the glycerate kinase type-1 family
MS6198_RS02535	COG3257	ureidoglycine aminohydrolase activity
MS6198_RS02540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MS6198_RS02545	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MS6198_RS02550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MS6198_RS02555	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MS6198_RS02565	COG0549	Belongs to the carbamate kinase family
MS6198_RS02570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MS6198_RS02575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MS6198_RS02585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MS6198_RS02595	COG1988	membrane-bound metal-dependent
MS6198_RS02600	COG2501	S4 domain
MS6198_RS02610	COG3539	Fimbrial protein
MS6198_RS02615	COG3121	Chaperone
MS6198_RS02620	COG3188	usher protein
MS6198_RS02625	COG3539	Fimbrial protein
MS6198_RS02630	COG3539	Fimbrial protein
MS6198_RS02635	COG2197	response regulator
MS6198_RS02645	COG0582	viral genome integration into host DNA
MS6198_RS02730	COG2076	Multidrug Resistance protein
MS6198_RS02740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MS6198_RS02790	COG3272	Protein of unknown function (DUF1722)
MS6198_RS02795	COG2207	Transcriptional regulator
MS6198_RS02820	COG3772	lysozyme
MS6198_RS02840	COG5562	phage envelope protein
MS6198_RS02850	COG4220	transposase activity
MS6198_RS02870	COG1030	water channel activity
MS6198_RS02920	COG1196	nuclear chromosome segregation
MS6198_RS02955	COG5301	cellulose 1,4-beta-cellobiosidase activity
MS6198_RS02970	COG2207	Transcriptional regulator
MS6198_RS02975	COG4571	Outer membrane protease
MS6198_RS02980	COG2207	Transcriptional regulator
MS6198_RS02990	COG4783	chaperone-mediated protein folding
MS6198_RS02995	COG1215	transferase activity, transferring glycosyl groups
MS6198_RS03000	COG5433	transposase activity
MS6198_RS03015	COG4104	PAAR repeat-containing protein
MS6198_RS03015	COG3209	COG3209 Rhs family protein
MS6198_RS03030	COG5002	protein histidine kinase activity
MS6198_RS03035	COG0745	RESPONSE REGULATOR receiver
MS6198_RS03040	COG1538	Outer membrane efflux protein
MS6198_RS03045	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS6198_RS03050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS6198_RS03055	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS6198_RS03060	COG1113	amino acid transport
MS6198_RS03065	COG0668	transmembrane transport
MS6198_RS03070	COG0778	Nitroreductase
MS6198_RS03075	COG2315	Protein conserved in bacteria
MS6198_RS03100	COG2977	Belongs to the P-Pant transferase superfamily
MS6198_RS03105	COG4771	TonB-dependent receptor
MS6198_RS03110	COG2382	esterase
MS6198_RS03115	COG3251	PFAM MbtH domain protein
MS6198_RS03120	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MS6198_RS03120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MS6198_RS03125	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
MS6198_RS03130	COG1120	ATPase activity
MS6198_RS03135	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS6198_RS03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS6198_RS03150	COG4592	Periplasmic binding protein
MS6198_RS03155	COG1169	isochorismate synthase
MS6198_RS03160	COG1021	2,3-dihydroxybenzoate-AMP ligase
MS6198_RS03165	COG3433	isochorismatase activity
MS6198_RS03165	COG1535	isochorismatase
MS6198_RS03170	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS03175	COG2050	protein possibly involved in aromatic compounds catabolism
MS6198_RS03180	COG1966	Carbon starvation protein
MS6198_RS03185	COG2879	small protein
MS6198_RS03190	COG0371	Dehydrogenase
MS6198_RS03195	COG0436	Aminotransferase
MS6198_RS03200	COG1475	DNA binding
MS6198_RS03205	COG3969	phosphoadenosine phosphosulfate
MS6198_RS03210	COG0583	DNA-binding transcription factor activity
MS6198_RS03215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MS6198_RS03220	COG0450	alkyl hydroperoxide reductase
MS6198_RS03225	COG3634	alkyl hydroperoxide reductase activity
MS6198_RS03230	COG0589	response to stress
MS6198_RS03235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MS6198_RS03240	COG3719	Belongs to the RNase T2 family
MS6198_RS03245	COG0471	metal ion transport
MS6198_RS03260	COG3051	citrate lyase alpha subunit
MS6198_RS03265	COG2301	Belongs to the HpcH HpaI aldolase family
MS6198_RS03275	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MS6198_RS03280	COG3290	protein histidine kinase activity
MS6198_RS03285	COG4565	transcriptional regulatory protein
MS6198_RS03290	COG3069	C4-dicarboxylate transmembrane transporter activity
MS6198_RS03310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MS6198_RS03315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MS6198_RS03325	COG0583	DNA-binding transcription factor activity
MS6198_RS03345	COG1686	Belongs to the peptidase S11 family
MS6198_RS03350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MS6198_RS03355	COG0772	Belongs to the SEDS family
MS6198_RS03360	COG0768	penicillin binding
MS6198_RS03370	COG0799	negative regulation of ribosome biogenesis
MS6198_RS03375	COG0406	alpha-ribazole phosphatase activity
MS6198_RS03385	COG1466	dna polymerase III delta subunit
MS6198_RS03400	COG2888	peptidyl-tyrosine sulfation
MS6198_RS03405	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MS6198_RS03415	COG2214	Heat shock protein DnaJ domain protein
MS6198_RS03420	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MS6198_RS03430	COG2214	Heat shock protein DnaJ domain protein
MS6198_RS03435	COG0443	Heat shock 70 kDa protein
MS6198_RS03445	COG1126	abc transporter atp-binding protein
MS6198_RS03450	COG0765	amino acid transport
MS6198_RS03455	COG0765	amino acid transport
MS6198_RS03460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS6198_RS03470	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MS6198_RS03475	COG4535	Mg2 and Co2 transporter CorC
MS6198_RS03485	COG1702	phosphate starvation-inducible protein PhoH
MS6198_RS03495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS6198_RS03540	COG0367	asparagine synthase
MS6198_RS03545	COG0647	UMP catabolic process
MS6198_RS03550	COG1940	carbohydrate kinase activity
MS6198_RS03550	COG1846	Transcriptional regulator
MS6198_RS03555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MS6198_RS03565	COG2190	(PTS) system
MS6198_RS03565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS03565	COG1263	PTS System
MS6198_RS03585	COG0735	belongs to the Fur family
MS6198_RS03600	COG0716	FMN binding
MS6198_RS03610	COG0596	Alpha beta hydrolase
MS6198_RS03615	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
MS6198_RS03620	COG0033	Phosphoglucomutase
MS6198_RS03645	COG0531	amino acid
MS6198_RS03650	COG1982	Orn Lys Arg decarboxylase major
MS6198_RS03660	COG0745	RESPONSE REGULATOR receiver
MS6198_RS03665	COG2205	protein histidine kinase activity
MS6198_RS03680	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MS6198_RS03695	COG3272	Protein of unknown function (DUF1722)
MS6198_RS03700	COG0415	Belongs to the DNA photolyase family
MS6198_RS03710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MS6198_RS03715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MS6198_RS03720	COG1984	allophanate hydrolase subunit 2
MS6198_RS03735	COG3180	Ammonia monooxygenase
MS6198_RS03740	COG2186	Transcriptional regulator
MS6198_RS03745	COG0473	3-isopropylmalate dehydrogenase activity
MS6198_RS03745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MS6198_RS03750	COG1063	alcohol dehydrogenase
MS6198_RS03755	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS03765	COG2721	sulfolactate sulfo-lyase activity
MS6198_RS03770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MS6198_RS03780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MS6198_RS03785	COG0372	Belongs to the citrate synthase family
MS6198_RS03795	COG2009	succinate dehydrogenase
MS6198_RS03800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MS6198_RS03805	COG1053	succinate dehydrogenase
MS6198_RS03810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MS6198_RS03820	COG0567	Dehydrogenase, E1 component
MS6198_RS03825	COG0508	dehydrogenase complex catalyzes the overall conversion of
MS6198_RS03835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MS6198_RS03845	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MS6198_RS03850	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MS6198_RS03860	COG1228	amidohydrolase
MS6198_RS03865	COG0010	Belongs to the arginase family
MS6198_RS03870	COG2986	histidine ammonia-lyase
MS6198_RS03875	COG0583	DNA-binding transcription factor activity
MS6198_RS03880	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
MS6198_RS03885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MS6198_RS03885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MS6198_RS03890	COG1301	dicarboxylic acid transport
MS6198_RS03905	COG3799	methylaspartate ammonia-lyase activity
MS6198_RS03910	COG4865	methylaspartate mutase activity
MS6198_RS03920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MS6198_RS03940	COG1271	oxidase subunit
MS6198_RS03945	COG1294	oxidase, subunit
MS6198_RS03950	COG4890	Cyd operon protein YbgT
MS6198_RS03955	COG3790	cyd operon protein YbgE
MS6198_RS03960	COG0824	Thioesterase
MS6198_RS03965	COG0811	peptide transport
MS6198_RS03970	COG0848	biopolymer transport protein
MS6198_RS03975	COG3064	Membrane
MS6198_RS03985	COG2885	chlorophyll binding
MS6198_RS03990	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MS6198_RS04040	COG3201	nicotinamide mononucleotide transporter
MS6198_RS04045	COG1230	cation diffusion facilitator family transporter
MS6198_RS04060	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MS6198_RS04070	COG2017	converts alpha-aldose to the beta-anomer
MS6198_RS04080	COG1085	galactose-1-phosphate uridylyltransferase
MS6198_RS04085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MS6198_RS04090	COG1119	ATPase activity
MS6198_RS04100	COG2005	Transcriptional regulator
MS6198_RS04100	COG3585	molybdate ion transport
MS6198_RS04110	COG0725	ABC transporter, periplasmic molybdate-binding protein
MS6198_RS04115	COG4149	molybdate abc transporter
MS6198_RS04125	COG0561	phosphatase activity
MS6198_RS04135	COG0583	DNA-binding transcription factor activity
MS6198_RS04140	COG2828	Protein conserved in bacteria
MS6198_RS04145	COG0471	metal ion transport
MS6198_RS04150	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MS6198_RS04155	COG4677	pectinesterase activity
MS6198_RS04160	COG1881	PFAM PEBP family protein
MS6198_RS04165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MS6198_RS04180	COG2226	methyltransferase
MS6198_RS04185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MS6198_RS04195	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MS6198_RS04205	COG0521	Mo-molybdopterin cofactor biosynthetic process
MS6198_RS04215	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MS6198_RS04220	COG0314	molybdopterin synthase activity
MS6198_RS04225	COG0670	Belongs to the BI1 family
MS6198_RS04230	COG0670	Belongs to the BI1 family
MS6198_RS04235	COG0392	lysyltransferase activity
MS6198_RS04240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MS6198_RS04245	COG3568	Endonuclease Exonuclease Phosphatase
MS6198_RS04255	COG0842	Transport permease protein
MS6198_RS04260	COG0842	Transport permease protein
MS6198_RS04265	COG1131	(ABC) transporter
MS6198_RS04275	COG1309	transcriptional regulator
MS6198_RS04280	COG0513	Belongs to the DEAD box helicase family
MS6198_RS04290	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
MS6198_RS04295	COG1199	ATP-dependent helicase activity
MS6198_RS04300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MS6198_RS04305	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MS6198_RS04315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MS6198_RS04325	COG4774	siderophore transport
MS6198_RS04340	COG0668	transmembrane transport
MS6198_RS04350	COG1126	abc transporter atp-binding protein
MS6198_RS04355	COG0765	amino acid transport
MS6198_RS04360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS6198_RS04375	COG5006	permease, DMT superfamily
MS6198_RS04380	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MS6198_RS04385	COG2194	sulfuric ester hydrolase activity
MS6198_RS04395	COG1321	iron dependent repressor
MS6198_RS04400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MS6198_RS04405	COG1376	ErfK ybiS ycfS ynhG family protein
MS6198_RS04410	COG0488	(ABC) transporter
MS6198_RS04420	COG2271	Major facilitator Superfamily
MS6198_RS04440	COG0561	phosphatase activity
MS6198_RS04445	COG1882	Formate acetyltransferase
MS6198_RS04450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MS6198_RS04455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MS6198_RS04460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MS6198_RS04465	COG0303	'Molybdopterin
MS6198_RS04470	COG1446	asparaginase
MS6198_RS04480	COG0747	negative chemotaxis
MS6198_RS04495	COG2200	EAL domain
MS6198_RS04500	COG2199	diguanylate cyclase activity
MS6198_RS04525	COG2133	pyrroloquinoline quinone binding
MS6198_RS04530	COG0625	glutathione transferase activity
MS6198_RS04535	COG1686	Belongs to the peptidase S11 family
MS6198_RS04540	COG1349	DNA-binding transcription factor activity
MS6198_RS04545	COG0671	phosphoesterase, PA-phosphatase related
MS6198_RS04550	COG2814	Major facilitator Superfamily
MS6198_RS04560	COG0561	phosphatase activity
MS6198_RS04565	COG0738	Major facilitator superfamily
MS6198_RS04570	COG3226	Transcriptional regulator
MS6198_RS04575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MS6198_RS04610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MS6198_RS04645	COG4695	Portal protein
MS6198_RS04735	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MS6198_RS04785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MS6198_RS04795	COG0778	Nitroreductase
MS6198_RS04815	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MS6198_RS04820	COG3842	ATPase activity
MS6198_RS04825	COG1176	ABC-type spermidine putrescine transport system, permease component I
MS6198_RS04830	COG1177	transmembrane transport
MS6198_RS04845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS6198_RS04850	COG4160	amino acid transport
MS6198_RS04855	COG4215	(ABC) transporter
MS6198_RS04860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS6198_RS04865	COG1126	abc transporter atp-binding protein
MS6198_RS04895	COG3023	N-Acetylmuramoyl-L-alanine amidase
MS6198_RS04900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MS6198_RS04905	COG0702	epimerase
MS6198_RS04910	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
MS6198_RS04915	COG0028	Belongs to the TPP enzyme family
MS6198_RS04920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS6198_RS04925	COG1151	hydroxylamine reductase activity
MS6198_RS04930	COG2431	L-lysine efflux transmembrane transporter activity
MS6198_RS04935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MS6198_RS04945	COG3593	DNA synthesis involved in DNA repair
MS6198_RS04950	COG2990	Protein conserved in bacteria
MS6198_RS04955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS6198_RS04960	COG1136	(ABC) transporter
MS6198_RS04960	COG0577	efflux transmembrane transporter activity
MS6198_RS04965	COG1278	Cold shock
MS6198_RS05030	COG0740	serine-type endopeptidase activity
MS6198_RS05050	COG0542	response to heat
MS6198_RS05075	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MS6198_RS05080	COG4988	ABC transporter
MS6198_RS05085	COG0492	ferredoxin-NADP+ reductase activity
MS6198_RS05090	COG1522	sequence-specific DNA binding
MS6198_RS05105	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MS6198_RS05115	COG0243	molybdopterin cofactor binding
MS6198_RS05120	COG0437	4 iron, 4 sulfur cluster binding
MS6198_RS05125	COG3302	dmso reductase anchor subunit
MS6198_RS05130	COG1335	isochorismatase
MS6198_RS05140	COG0531	amino acid
MS6198_RS05145	COG0583	DNA-binding transcription factor activity
MS6198_RS05150	COG2249	NAD(P)H dehydrogenase (quinone) activity
MS6198_RS05155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MS6198_RS05160	COG1882	Formate acetyltransferase
MS6198_RS05165	COG2116	formate transmembrane transporter activity
MS6198_RS05170	COG1944	ATP diphosphatase activity
MS6198_RS05175	COG2323	membrane
MS6198_RS05190	COG0501	Belongs to the peptidase M48B family
MS6198_RS05200	COG0539	negative regulation of cytoplasmic translation
MS6198_RS05210	COG2333	competence protein COMEC
MS6198_RS05210	COG0658	competence protein
MS6198_RS05215	COG1132	(ABC) transporter
MS6198_RS05225	COG3214	Protein conserved in bacteria
MS6198_RS05240	COG3173	Aminoglycoside phosphotransferase
MS6198_RS05245	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MS6198_RS05250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MS6198_RS05260	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
MS6198_RS05270	COG2989	Protein conserved in bacteria
MS6198_RS05275	COG3108	Peptidase M15
MS6198_RS05280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS6198_RS05285	COG1448	Aminotransferase
MS6198_RS05310	COG0308	aminopeptidase N
MS6198_RS05315	COG1116	anion transmembrane transporter activity
MS6198_RS05320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MS6198_RS05330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MS6198_RS05335	COG0431	NADPH-dependent FMN reductase
MS6198_RS05340	COG3539	Fimbrial protein
MS6198_RS05345	COG3121	Chaperone
MS6198_RS05350	COG3188	usher protein
MS6198_RS05355	COG3539	Fimbrial protein
MS6198_RS05360	COG3539	Fimbrial protein
MS6198_RS05365	COG3539	Fimbrial protein
MS6198_RS05370	COG3121	Chaperone
MS6198_RS05385	COG0633	Ferredoxin
MS6198_RS05385	COG3217	Mosc domain protein beta barrel domain protein
MS6198_RS05395	COG0488	(ABC) transporter
MS6198_RS05400	COG2995	paraquat-inducible protein a
MS6198_RS05405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MS6198_RS05405	COG3008	intermembrane lipid transfer
MS6198_RS05410	COG3009	Protein conserved in bacteria
MS6198_RS05415	COG3130	regulation of translation
MS6198_RS05425	COG1067	ATP-dependent peptidase activity
MS6198_RS05435	COG2885	chlorophyll binding
MS6198_RS05435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MS6198_RS05450	COG3070	regulator of competence-specific genes
MS6198_RS05455	COG1289	transmembrane transporter activity
MS6198_RS05460	COG3304	Inner membrane component domain
MS6198_RS05465	COG0210	DNA helicase
MS6198_RS05485	COG1832	CoA-binding protein
MS6198_RS05500	COG1254	Belongs to the acylphosphatase family
MS6198_RS05505	COG2920	part of a sulfur-relay system
MS6198_RS05510	COG0670	Belongs to the BI1 family
MS6198_RS05520	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
MS6198_RS05525	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
MS6198_RS05530	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
MS6198_RS05535	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MS6198_RS05540	COG1999	signal sequence binding
MS6198_RS05545	COG1773	rubredoxin
MS6198_RS05550	COG1271	oxidase subunit
MS6198_RS05555	COG1294	oxidase, subunit
MS6198_RS05570	COG1278	Cold shock
MS6198_RS05575	COG1278	Cold shock
MS6198_RS05590	COG0348	domain, Protein
MS6198_RS05595	COG0784	Response regulator, receiver
MS6198_RS05595	COG2198	Histidine kinase
MS6198_RS05595	COG2205	protein histidine kinase activity
MS6198_RS05600	COG1879	ABC-type sugar transport system periplasmic component
MS6198_RS05605	COG0745	RESPONSE REGULATOR receiver
MS6198_RS05610	COG3005	denitrification pathway
MS6198_RS05615	COG0243	molybdopterin cofactor binding
MS6198_RS05660	COG3729	General stress protein
MS6198_RS05665	COG2233	PERMEase
MS6198_RS05670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS6198_RS05700	COG1309	transcriptional regulator
MS6198_RS05705	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MS6198_RS05705	COG0506	proline dehydrogenase activity
MS6198_RS05705	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MS6198_RS05715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MS6198_RS05735	COG1702	phosphate starvation-inducible protein PhoH
MS6198_RS05740	COG3658	cytochrome
MS6198_RS05745	COG1215	transferase activity, transferring glycosyl groups
MS6198_RS05750	COG0726	polysaccharide deacetylase
MS6198_RS05750	COG1649	PFAM Uncharacterised BCR, COG1649
MS6198_RS05755	COG0457	Tetratricopeptide repeat
MS6198_RS05760	COG3706	GGDEF domain
MS6198_RS05785	COG3381	protein complex oligomerization
MS6198_RS05795	COG1462	curli production assembly transport component CsgG
MS6198_RS05810	COG2197	response regulator
MS6198_RS05840	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MS6198_RS05845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MS6198_RS05870	COG2943	transferase activity, transferring hexosyl groups
MS6198_RS05875	COG5645	(Lipo)protein
MS6198_RS05895	COG1560	Kdo2-lipid A biosynthetic process
MS6198_RS05905	COG2353	YceI-like domain
MS6198_RS05910	COG3038	cytochrome b561
MS6198_RS05945	COG2999	glutathione oxidoreductase activity
MS6198_RS05955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS6198_RS05965	COG0673	inositol 2-dehydrogenase activity
MS6198_RS05970	COG0728	peptidoglycan biosynthetic process
MS6198_RS05975	COG3418	PFAM FlgN family protein
MS6198_RS05980	COG2747	anti-sigma28 factor FlgM
MS6198_RS05985	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
MS6198_RS05990	COG1815	bacterial-type flagellum-dependent cell motility
MS6198_RS05995	COG1558	bacterial-type flagellum-dependent cell motility
MS6198_RS06000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MS6198_RS06005	COG1749	Flagellar hook protein flgE
MS6198_RS06010	COG4787	bacterial-type flagellum-dependent cell motility
MS6198_RS06015	COG4786	Flagellar basal body rod
MS6198_RS06025	COG1706	bacterial-type flagellum-dependent cell motility
MS6198_RS06030	COG1705	Flagellar rod assembly protein muramidase FlgJ
MS6198_RS06030	COG3951	Flagellar rod assembly protein muramidase FlgJ
MS6198_RS06035	COG1256	bacterial-type flagellum assembly
MS6198_RS06040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MS6198_RS06055	COG1530	ribonuclease E activity
MS6198_RS06065	COG0564	pseudouridine synthase activity
MS6198_RS06070	COG0424	maF-like protein
MS6198_RS06075	COG1399	metal-binding, possibly nucleic acid-binding protein
MS6198_RS06095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MS6198_RS06100	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS06110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MS6198_RS06115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MS6198_RS06120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MS6198_RS06130	COG0470	DNA polymerase III
MS6198_RS06135	COG0084	hydrolase, TatD family'
MS6198_RS06140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS06140	COG1263	PTS System
MS6198_RS06145	COG4773	Receptor
MS6198_RS06150	COG0537	adenosine 5'-monophosphoramidase activity
MS6198_RS06155	COG5633	Lipoprotein
MS6198_RS06160	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
MS6198_RS06180	COG1252	NADH dehydrogenase
MS6198_RS06185	COG3134	Outer membrane lipoprotein
MS6198_RS06190	COG1309	transcriptional regulator
MS6198_RS06200	COG1388	LysM domain
MS6198_RS06200	COG1376	ErfK ybiS ycfS ynhG family protein
MS6198_RS06205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MS6198_RS06210	COG4763	Acyl-transferase
MS6198_RS06215	COG4591	ABC-type transport system involved in lipoprotein release permease component
MS6198_RS06225	COG4591	ABC-type transport system involved in lipoprotein release permease component
MS6198_RS06235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MS6198_RS06240	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MS6198_RS06250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MS6198_RS06255	COG1177	transmembrane transport
MS6198_RS06265	COG3842	ATPase activity
MS6198_RS06280	COG2850	peptidyl-arginine hydroxylation
MS6198_RS06285	COG2205	protein histidine kinase activity
MS6198_RS06295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MS6198_RS06315	COG1187	pseudouridine synthase activity
MS6198_RS06335	COG0538	isocitrate dehydrogenase activity
MS6198_RS06350	COG5562	phage envelope protein
MS6198_RS06355	COG0789	Transcriptional regulator
MS6198_RS06360	COG2200	EAL domain
MS6198_RS06385	COG2200	EAL domain
MS6198_RS06430	COG2894	cell division
MS6198_RS06460	COG0179	Fumarylacetoacetate (FAA) hydrolase
MS6198_RS06475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MS6198_RS06480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MS6198_RS06485	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MS6198_RS06500	COG2719	SpoVR family
MS6198_RS06510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MS6198_RS06525	COG1619	proteins homologs of microcin C7 resistance protein MccF
MS6198_RS06535	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MS6198_RS06550	COG0157	Belongs to the NadC ModD family
MS6198_RS06555	COG0500	methyltransferase
MS6198_RS06560	COG1120	ATPase activity
MS6198_RS06565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS6198_RS06570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MS6198_RS06580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MS6198_RS06580	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MS6198_RS06580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS06585	COG1461	Dihydroxyacetone kinase
MS6198_RS06590	COG2376	Dihydroxyacetone kinase
MS6198_RS06595	COG3284	Transcriptional regulator
MS6198_RS06640	COG1396	sequence-specific DNA binding
MS6198_RS06655	COG2003	Belongs to the UPF0758 family
MS6198_RS06660	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MS6198_RS06730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MS6198_RS06755	COG0582	viral genome integration into host DNA
MS6198_RS06760	COG0012	GTP binding
MS6198_RS06775	COG0659	secondary active sulfate transmembrane transporter activity
MS6198_RS06780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MS6198_RS06805	COG2890	protein-(glutamine-N5) methyltransferase activity
MS6198_RS06810	COG3094	Invasion gene expression up-regulator, SirB
MS6198_RS06815	COG2912	Transglutaminase-like superfamily
MS6198_RS06835	COG0387	Pfam Sodium calcium exchanger
MS6198_RS06840	COG4572	Cation transport regulator
MS6198_RS06845	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MS6198_RS06850	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MS6198_RS06855	COG4932	domain protein
MS6198_RS06860	COG2197	response regulator
MS6198_RS06865	COG3850	Histidine kinase
MS6198_RS06875	COG2223	nitrite transmembrane transporter activity
MS6198_RS06880	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MS6198_RS06885	COG1140	nitrate reductase beta subunit
MS6198_RS06890	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MS6198_RS06895	COG2181	nitrate reductase activity
MS6198_RS06910	COG0788	formyltetrahydrofolate deformylase activity
MS6198_RS06920	COG1752	Esterase of the alpha-beta hydrolase superfamily
MS6198_RS06925	COG0745	RESPONSE REGULATOR receiver
MS6198_RS06930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MS6198_RS06940	COG1435	thymidine kinase activity
MS6198_RS06945	COG3385	transposase activity
MS6198_RS06950	COG1454	alcohol dehydrogenase
MS6198_RS06950	COG1012	belongs to the aldehyde dehydrogenase family
MS6198_RS06955	COG2095	MarC family integral membrane protein
MS6198_RS06960	COG4166	transmembrane transport
MS6198_RS06965	COG0601	transmembrane transport
MS6198_RS06970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS6198_RS06975	COG0444	Belongs to the ABC transporter superfamily
MS6198_RS06980	COG4608	Belongs to the ABC transporter superfamily
MS6198_RS07000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MS6198_RS07005	COG2350	Protein conserved in bacteria
MS6198_RS07015	COG1607	acyl-coa hydrolase
MS6198_RS07030	COG3047	cAMP biosynthetic process
MS6198_RS07035	COG0582	viral genome integration into host DNA
MS6198_RS07045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MS6198_RS07145	COG1403	HNH endonuclease
MS6198_RS07150	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MS6198_RS07155	COG0484	heat shock protein binding
MS6198_RS07200	COG3772	lysozyme
MS6198_RS07220	COG4220	transposase activity
MS6198_RS07240	COG1030	water channel activity
MS6198_RS07290	COG1196	nuclear chromosome segregation
MS6198_RS07320	COG5301	cellulose 1,4-beta-cellobiosidase activity
MS6198_RS07340	COG0500	methyltransferase
MS6198_RS07360	COG3685	Protein conserved in bacteria
MS6198_RS07365	COG3729	General stress protein
MS6198_RS07370	COG0159	tryptophan synthase activity
MS6198_RS07380	COG0134	indole-3-glycerol-phosphate synthase activity
MS6198_RS07380	COG0135	phosphoribosylanthranilate isomerase activity
MS6198_RS07385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MS6198_RS07385	COG0512	Glutamine amidotransferase of anthranilate synthase
MS6198_RS07390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MS6198_RS07395	COG0613	PHP domain protein
MS6198_RS07400	COG0009	L-threonylcarbamoyladenylate synthase
MS6198_RS07405	COG4907	membrane protein (DUF2207)
MS6198_RS07410	COG1187	pseudouridine synthase activity
MS6198_RS07425	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
MS6198_RS07430	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS07440	COG0616	signal peptide processing
MS6198_RS07455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MS6198_RS07460	COG0583	DNA-binding transcription factor activity
MS6198_RS07480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MS6198_RS07490	COG0671	phosphoesterase, PA-phosphatase related
MS6198_RS07495	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
MS6198_RS07500	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MS6198_RS07510	COG0023	Translation Initiation Factor
MS6198_RS07520	COG1349	DNA-binding transcription factor activity
MS6198_RS07530	COG5001	Diguanylate cyclase
MS6198_RS07545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS6198_RS07545	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS6198_RS07550	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MS6198_RS07560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS6198_RS07565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS6198_RS07575	COG2814	Major facilitator Superfamily
MS6198_RS07580	COG4172	Belongs to the ABC transporter superfamily
MS6198_RS07585	COG4172	Belongs to the ABC transporter superfamily
MS6198_RS07590	COG4171	peptide transport system, permease
MS6198_RS07595	COG4168	peptide transport system, permease
MS6198_RS07600	COG4166	transmembrane transport
MS6198_RS07615	COG0531	amino acid
MS6198_RS07620	COG0174	glutamine synthetase
MS6198_RS07625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MS6198_RS07630	COG1917	Cupin 2, conserved barrel domain protein
MS6198_RS07630	COG1396	sequence-specific DNA binding
MS6198_RS07635	COG1012	belongs to the aldehyde dehydrogenase family
MS6198_RS07640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MS6198_RS07645	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MS6198_RS07650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MS6198_RS07655	COG1842	Phage shock protein A
MS6198_RS07665	COG1983	PspC domain protein
MS6198_RS07675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MS6198_RS07680	COG0366	Alpha amylase catalytic
MS6198_RS07685	COG1653	transport
MS6198_RS07690	COG1175	transmembrane transport
MS6198_RS07695	COG0395	ABC-type sugar transport system, permease component
MS6198_RS07700	COG1063	alcohol dehydrogenase
MS6198_RS07705	COG1082	Xylose isomerase domain protein TIM barrel
MS6198_RS07710	COG0673	inositol 2-dehydrogenase activity
MS6198_RS07715	COG1554	hydrolase, family 65, central catalytic
MS6198_RS07720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS6198_RS07725	COG3842	ATPase activity
MS6198_RS07735	COG1609	Transcriptional regulator
MS6198_RS07740	COG3106	COG3106 Predicted ATPase
MS6198_RS07750	COG3283	Transcriptional regulator of aromatic amino acids metabolism
MS6198_RS07755	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MS6198_RS07760	COG4948	Mandelate Racemase Muconate Lactonizing
MS6198_RS07765	COG2866	Carboxypeptidase
MS6198_RS07770	COG4166	transmembrane transport
MS6198_RS07775	COG0668	transmembrane transport
MS6198_RS07780	COG3182	Iron-regulated membrane protein
MS6198_RS07785	COG0589	response to stress
MS6198_RS07790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MS6198_RS07795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MS6198_RS07800	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MS6198_RS07810	COG1473	amidohydrolase
MS6198_RS07815	COG1473	amidohydrolase
MS6198_RS07820	COG0583	DNA-binding transcription factor activity
MS6198_RS07830	COG2840	Smr protein MutS2
MS6198_RS07835	COG3706	GGDEF domain
MS6198_RS07850	COG0513	Belongs to the DEAD box helicase family
MS6198_RS07860	COG0589	response to stress
MS6198_RS07865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MS6198_RS07870	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MS6198_RS07870	COG1013	pyruvate-flavodoxin oxidoreductase activity
MS6198_RS07870	COG0674	pyruvate-flavodoxin oxidoreductase activity
MS6198_RS07870	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MS6198_RS07875	COG3042	response to heat
MS6198_RS07880	COG3187	Heat shock protein
MS6198_RS07885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MS6198_RS07890	COG2911	Protein conserved in bacteria
MS6198_RS07900	COG3784	Protein of unknown function (DUF1318)
MS6198_RS07905	COG3327	negative regulation of DNA-templated transcription, initiation
MS6198_RS07910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MS6198_RS07915	COG0667	Aldo Keto reductase
MS6198_RS07925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MS6198_RS07930	COG4589	Belongs to the CDS family
MS6198_RS07935	COG2267	carboxylic ester hydrolase activity
MS6198_RS07940	COG2453	phosphatase
MS6198_RS07940	COG0671	phosphoesterase, PA-phosphatase related
MS6198_RS07950	COG1643	Atp-dependent helicase
MS6198_RS07955	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MS6198_RS07960	COG1012	belongs to the aldehyde dehydrogenase family
MS6198_RS07965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MS6198_RS07970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MS6198_RS07975	COG3038	cytochrome b561
MS6198_RS07990	COG0840	transmembrane signaling receptor activity
MS6198_RS07995	COG0583	DNA-binding transcription factor activity
MS6198_RS08000	COG5383	Protein conserved in bacteria
MS6198_RS08015	COG2841	Protein conserved in bacteria
MS6198_RS08020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS6198_RS08025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MS6198_RS08030	COG1275	C4-dicarboxylate transporter malic acid transport protein
MS6198_RS08035	COG0500	methyltransferase
MS6198_RS08045	COG3135	benzoate transporter
MS6198_RS08050	COG1396	sequence-specific DNA binding
MS6198_RS08055	COG0826	peptidase U32
MS6198_RS08065	COG1724	mRNA binding
MS6198_RS08070	COG1598	PFAM Uncharacterised protein family UPF0150
MS6198_RS08075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS6198_RS08080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MS6198_RS08085	COG3842	ATPase activity
MS6198_RS08090	COG1176	ABC-type spermidine putrescine transport system, permease component I
MS6198_RS08095	COG1177	transmembrane transport
MS6198_RS08120	COG3238	Protein conserved in bacteria
MS6198_RS08125	COG1247	-acetyltransferase
MS6198_RS08130	COG2130	NADP-dependent
MS6198_RS08135	COG1802	Transcriptional regulator
MS6198_RS08140	COG4772	TonB-dependent receptor
MS6198_RS08150	COG1113	amino acid transport
MS6198_RS08155	COG0625	glutathione transferase activity
MS6198_RS08170	COG5433	transposase activity
MS6198_RS08190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS6198_RS08195	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MS6198_RS08200	COG0384	phenazine biosynthesis protein PhzF
MS6198_RS08205	COG2181	nitrate reductase activity
MS6198_RS08210	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MS6198_RS08215	COG1140	nitrate reductase beta subunit
MS6198_RS08220	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MS6198_RS08225	COG2223	nitrite transmembrane transporter activity
MS6198_RS08230	COG4886	Leucine-rich repeat (LRR) protein
MS6198_RS08235	COG4886	Leucine-rich repeat (LRR) protein
MS6198_RS08245	COG0697	spore germination
MS6198_RS08250	COG3383	formate dehydrogenase (NAD+) activity
MS6198_RS08250	COG0243	molybdopterin cofactor binding
MS6198_RS08255	COG0243	molybdopterin cofactor binding
MS6198_RS08255	COG3383	formate dehydrogenase (NAD+) activity
MS6198_RS08260	COG0437	4 iron, 4 sulfur cluster binding
MS6198_RS08265	COG2864	formate dehydrogenase
MS6198_RS08270	COG3093	addiction module antidote protein HigA
MS6198_RS08275	COG1064	alcohol dehydrogenase
MS6198_RS08295	COG1764	response to oxidative stress
MS6198_RS08300	COG4608	Belongs to the ABC transporter superfamily
MS6198_RS08305	COG0444	Belongs to the ABC transporter superfamily
MS6198_RS08310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS6198_RS08315	COG0601	transmembrane transport
MS6198_RS08320	COG0747	negative chemotaxis
MS6198_RS08325	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MS6198_RS08330	COG2199	diguanylate cyclase activity
MS6198_RS08330	COG2200	EAL domain
MS6198_RS08330	COG2202	Pas domain
MS6198_RS08340	COG1649	PFAM Uncharacterised BCR, COG1649
MS6198_RS08345	COG0531	amino acid
MS6198_RS08350	COG0076	glutamate decarboxylase activity
MS6198_RS08360	COG0612	Peptidase, M16
MS6198_RS08365	COG4771	TonB-dependent receptor
MS6198_RS08370	COG4178	(ABC) transporter
MS6198_RS08375	COG0641	radical SAM
MS6198_RS08380	COG3119	arylsulfatase activity
MS6198_RS08395	COG0243	molybdopterin cofactor binding
MS6198_RS08400	COG3539	Fimbrial protein
MS6198_RS08405	COG3539	Fimbrial protein
MS6198_RS08410	COG3539	Fimbrial protein
MS6198_RS08415	COG3188	usher protein
MS6198_RS08445	COG4977	sequence-specific DNA binding
MS6198_RS08505	COG3781	membrane
MS6198_RS08520	COG2199	diguanylate cyclase activity
MS6198_RS08530	COG2066	Belongs to the glutaminase family
MS6198_RS08535	COG1012	belongs to the aldehyde dehydrogenase family
MS6198_RS08540	COG0583	DNA-binding transcription factor activity
MS6198_RS08560	COG1846	Transcriptional regulator
MS6198_RS08565	COG4977	sequence-specific DNA binding
MS6198_RS08575	COG0697	spore germination
MS6198_RS08580	COG2814	Major facilitator Superfamily
MS6198_RS08590	COG3706	GGDEF domain
MS6198_RS08595	COG3111	PFAM Bacterial OB fold (BOF) protein
MS6198_RS08605	COG0339	signal peptide processing
MS6198_RS08610	COG4221	oxidoreductase activity
MS6198_RS08615	COG1802	Transcriptional regulator
MS6198_RS08625	COG0246	Mannitol dehydrogenase
MS6198_RS08630	COG0477	Major facilitator Superfamily
MS6198_RS08640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MS6198_RS08660	COG5301	cellulose 1,4-beta-cellobiosidase activity
MS6198_RS08685	COG0740	serine-type endopeptidase activity
MS6198_RS08715	COG5562	phage envelope protein
MS6198_RS08725	COG3772	lysozyme
MS6198_RS08745	COG3064	Membrane
MS6198_RS08760	COG0484	heat shock protein binding
MS6198_RS08765	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MS6198_RS08770	COG1403	HNH endonuclease
MS6198_RS08840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MS6198_RS08850	COG0582	viral genome integration into host DNA
MS6198_RS08855	COG1063	alcohol dehydrogenase
MS6198_RS08860	COG4948	Mandelate Racemase Muconate Lactonizing
MS6198_RS08875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS6198_RS08890	COG0243	molybdopterin cofactor binding
MS6198_RS08895	COG0243	molybdopterin cofactor binding
MS6198_RS08900	COG0437	4 iron, 4 sulfur cluster binding
MS6198_RS08905	COG3302	dmso reductase anchor subunit
MS6198_RS08910	COG3381	protein complex oligomerization
MS6198_RS08920	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MS6198_RS08925	COG1940	carbohydrate kinase activity
MS6198_RS08930	COG0583	DNA-binding transcription factor activity
MS6198_RS08935	COG2814	Major facilitator Superfamily
MS6198_RS08950	COG3591	Belongs to the peptidase S1B family
MS6198_RS08965	COG0628	permease
MS6198_RS08970	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MS6198_RS08975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MS6198_RS08985	COG0531	amino acid
MS6198_RS08995	COG3136	membrane protein required for alginate biosynthesis
MS6198_RS09000	COG0745	RESPONSE REGULATOR receiver
MS6198_RS09005	COG2205	protein histidine kinase activity
MS6198_RS09015	COG0114	fumarate hydratase activity
MS6198_RS09020	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MS6198_RS09020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MS6198_RS09025	COG1482	cell wall glycoprotein biosynthetic process
MS6198_RS09030	COG5339	Protein conserved in bacteria
MS6198_RS09035	COG3250	beta-galactosidase activity
MS6198_RS09040	COG1309	transcriptional regulator
MS6198_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS09050	COG1609	Transcriptional regulator
MS6198_RS09055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS09055	COG1263	PTS System
MS6198_RS09060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MS6198_RS09070	COG0673	inositol 2-dehydrogenase activity
MS6198_RS09110	COG4659	FMN binding
MS6198_RS09120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MS6198_RS09130	COG3104	oligopeptide transport
MS6198_RS09135	COG0625	glutathione transferase activity
MS6198_RS09140	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MS6198_RS09155	COG3895	Periplasmic Protein
MS6198_RS09165	COG3133	Outer membrane lipoprotein
MS6198_RS09180	COG1566	PFAM secretion protein HlyD family protein
MS6198_RS09185	COG1289	transmembrane transporter activity
MS6198_RS09190	COG2032	superoxide dismutase activity
MS6198_RS09195	COG4989	oxidoreductase activity
MS6198_RS09200	COG3313	Fe-S protein
MS6198_RS09205	COG1309	transcriptional regulator
MS6198_RS09210	COG1902	pentaerythritol trinitrate reductase activity
MS6198_RS09215	COG0346	lactoylglutathione lyase activity
MS6198_RS09225	COG1201	RNA secondary structure unwinding
MS6198_RS09230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MS6198_RS09235	COG0791	NLP P60 protein
MS6198_RS09240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MS6198_RS09245	COG2814	Major facilitator Superfamily
MS6198_RS09260	COG0583	DNA-binding transcription factor activity
MS6198_RS09265	COG2814	Major facilitator Superfamily
MS6198_RS09270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MS6198_RS09275	COG0307	riboflavin synthase, alpha
MS6198_RS09285	COG3468	outer membrane autotransporter barrel domain protein
MS6198_RS09305	COG4529	Protein conserved in bacteria
MS6198_RS09315	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
MS6198_RS09320	COG0437	4 iron, 4 sulfur cluster binding
MS6198_RS09330	COG2414	aldehyde ferredoxin oxidoreductase
MS6198_RS09335	COG0437	4 iron, 4 sulfur cluster binding
MS6198_RS09345	COG0469	pyruvate kinase activity
MS6198_RS09350	COG4238	major outer membrane lipoprotein
MS6198_RS09355	COG1376	ErfK ybiS ycfS ynhG family protein
MS6198_RS09370	COG0719	Fe-S assembly protein
MS6198_RS09375	COG0396	ATPase activity
MS6198_RS09380	COG0719	Fe-S assembly protein
MS6198_RS09385	COG0316	Belongs to the HesB IscA family
MS6198_RS09395	COG2050	protein possibly involved in aromatic compounds catabolism
MS6198_RS09400	COG0277	FAD linked oxidase domain protein
MS6198_RS09400	COG0247	lactate metabolic process
MS6198_RS09405	COG0628	permease
MS6198_RS09420	COG0738	Major facilitator superfamily
MS6198_RS09425	COG2271	Major facilitator Superfamily
MS6198_RS09440	COG4670	ketone body catabolic process
MS6198_RS09445	COG1960	acyl-CoA dehydrogenase activity
MS6198_RS09450	COG2207	Transcriptional regulator
MS6198_RS09450	COG1917	Cupin 2, conserved barrel domain protein
MS6198_RS09460	COG2086	electron transfer activity
MS6198_RS09465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MS6198_RS09470	COG0644	oxidoreductase
MS6198_RS09475	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MS6198_RS09480	COG0318	PFAM AMP-dependent synthetase and ligase
MS6198_RS09485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MS6198_RS09485	COG0574	Belongs to the PEP-utilizing enzyme family
MS6198_RS09500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MS6198_RS09505	COG4256	Hemin uptake protein
MS6198_RS09515	COG2200	EAL domain
MS6198_RS09520	COG0791	NLP P60 protein
MS6198_RS09530	COG0386	Belongs to the glutathione peroxidase family
MS6198_RS09585	COG3137	Salt-induced outer membrane protein
MS6198_RS09590	COG1105	Belongs to the carbohydrate kinase PfkB family
MS6198_RS09600	COG3001	Fructosamine kinase
MS6198_RS09610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS6198_RS09615	COG1988	membrane-bound metal-dependent
MS6198_RS09620	COG1823	symporter activity
MS6198_RS09635	COG0753	catalase activity
MS6198_RS09645	COG1486	melibiose metabolic process
MS6198_RS09650	COG1917	Cupin 2, conserved barrel domain protein
MS6198_RS09650	COG2169	Transcriptional regulator
MS6198_RS09655	COG1447	Phosphotransferase system cellobiose-specific component IIA
MS6198_RS09660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS6198_RS09665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS6198_RS09670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS6198_RS09685	COG0322	excinuclease ABC activity
MS6198_RS09695	COG3678	ATP-independent chaperone mediated protein folding
MS6198_RS09725	COG0708	Exodeoxyribonuclease III
MS6198_RS09730	COG0398	Pfam SNARE associated Golgi protein
MS6198_RS09740	COG0398	Pfam SNARE associated Golgi protein
MS6198_RS09745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS6198_RS09750	COG4134	Bacterial extracellular solute-binding protein
MS6198_RS09755	COG4135	transport system, permease component
MS6198_RS09760	COG4136	ATPase activity
MS6198_RS09765	COG2897	thiosulfate sulfurtransferase activity
MS6198_RS09770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MS6198_RS09775	COG0494	nUDIX hydrolase
MS6198_RS09785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MS6198_RS09790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MS6198_RS09805	COG0778	Nitroreductase
MS6198_RS09815	COG0616	signal peptide processing
MS6198_RS09820	COG0252	asparaginase activity
MS6198_RS09825	COG1335	isochorismatase
MS6198_RS09830	COG2814	Major facilitator Superfamily
MS6198_RS09835	COG1349	DNA-binding transcription factor activity
MS6198_RS09840	COG0667	Aldo Keto reductase
MS6198_RS09845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS09850	COG0191	fructose-bisphosphate aldolase activity
MS6198_RS09855	COG1063	alcohol dehydrogenase
MS6198_RS09865	COG1063	alcohol dehydrogenase
MS6198_RS09870	COG3139	Protein of unknown function (DUF1315)
MS6198_RS09880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MS6198_RS09885	COG0676	glucose-6-phosphate 1-epimerase activity
MS6198_RS09890	COG0656	L-ascorbic acid biosynthetic process
MS6198_RS09895	COG3713	MltA-interacting MipA family protein
MS6198_RS09900	COG2766	serine protein kinase
MS6198_RS09910	COG2199	diguanylate cyclase activity
MS6198_RS09915	COG2199	diguanylate cyclase activity
MS6198_RS09920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MS6198_RS09935	COG2207	Transcriptional regulator
MS6198_RS09940	COG2807	transmembrane transport
MS6198_RS09945	COG3189	MarR family transcriptional regulator
MS6198_RS09950	COG3042	response to heat
MS6198_RS09955	COG2203	Gaf domain
MS6198_RS09955	COG2199	diguanylate cyclase activity
MS6198_RS09965	COG2261	transglycosylase associated protein
MS6198_RS09975	COG3615	Tellurite resistance protein tehB
MS6198_RS09985	COG0583	DNA-binding transcription factor activity
MS6198_RS09990	COG0473	3-isopropylmalate dehydrogenase activity
MS6198_RS09995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS6198_RS10000	COG4638	Rieske (2fe-2S)
MS6198_RS10005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS6198_RS10010	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MS6198_RS10015	COG0318	PFAM AMP-dependent synthetase and ligase
MS6198_RS10020	COG3065	identical protein binding
MS6198_RS10025	COG1214	PFAM Peptidase M22, glycoprotease
MS6198_RS10030	COG1199	ATP-dependent helicase activity
MS6198_RS10035	COG0251	oxidation-reduction process
MS6198_RS10055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MS6198_RS10060	COG0494	nUDIX hydrolase
MS6198_RS10065	COG1760	l-serine dehydratase
MS6198_RS10070	COG2200	EAL domain
MS6198_RS10075	COG1253	flavin adenine dinucleotide binding
MS6198_RS10085	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS10085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS10090	COG3715	PTS system
MS6198_RS10095	COG3716	PTS system mannose fructose sorbose family IID component
MS6198_RS10110	COG2226	methyltransferase
MS6198_RS10145	COG1414	Transcriptional regulator
MS6198_RS10150	COG2814	Major facilitator Superfamily
MS6198_RS10160	COG0793	Belongs to the peptidase S41A family
MS6198_RS10170	COG1956	GAF domain-containing protein
MS6198_RS10175	COG2995	paraquat-inducible protein a
MS6198_RS10180	COG3008	intermembrane lipid transfer
MS6198_RS10200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MS6198_RS10215	COG1276	copper resistance
MS6198_RS10220	COG2372	response to copper ion
MS6198_RS10230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MS6198_RS10235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MS6198_RS10240	COG1770	oligopeptidase
MS6198_RS10245	COG2979	Protein of unknown function (DUF533)
MS6198_RS10260	COG3141	response to X-ray
MS6198_RS10270	COG0800	Aldolase
MS6198_RS10275	COG0129	dihydroxy-acid dehydratase activity
MS6198_RS10280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MS6198_RS10290	COG1737	Transcriptional regulator
MS6198_RS10295	COG0469	pyruvate kinase activity
MS6198_RS10300	COG1560	Kdo2-lipid A biosynthetic process
MS6198_RS10305	COG0739	heme binding
MS6198_RS10310	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
MS6198_RS10320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MS6198_RS10345	COG0217	transcriptional regulatory protein
MS6198_RS10350	COG0494	nUDIX hydrolase
MS6198_RS10360	COG1335	isochorismatase
MS6198_RS10365	COG1801	Protein of unknown function DUF72
MS6198_RS10370	COG3788	relative of glutathione S-transferase, MAPEG superfamily
MS6198_RS10385	COG0243	molybdopterin cofactor binding
MS6198_RS10390	COG3005	denitrification pathway
MS6198_RS10400	COG3102	Protein conserved in bacteria
MS6198_RS10415	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MS6198_RS10420	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MS6198_RS10425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MS6198_RS10435	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MS6198_RS10440	COG0745	RESPONSE REGULATOR receiver
MS6198_RS10450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MS6198_RS10455	COG0840	transmembrane signaling receptor activity
MS6198_RS10460	COG0840	transmembrane signaling receptor activity
MS6198_RS10465	COG0835	chemotaxis
MS6198_RS10470	COG0643	Histidine kinase
MS6198_RS10470	COG2198	Histidine kinase
MS6198_RS10475	COG1360	Flagellar Motor Protein
MS6198_RS10480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MS6198_RS10495	COG0589	response to stress
MS6198_RS10505	COG1877	trehalose-phosphatase activity
MS6198_RS10510	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS6198_RS10515	COG1129	ABC transporter
MS6198_RS10520	COG1879	ABC-type sugar transport system periplasmic component
MS6198_RS10525	COG1528	Iron-storage protein
MS6198_RS10545	COG1528	Iron-storage protein
MS6198_RS10555	COG0814	amino acid
MS6198_RS10560	COG3012	SEC-C Motif Domain Protein
MS6198_RS10560	COG3318	Belongs to the UPF0149 family
MS6198_RS10580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MS6198_RS10590	COG3318	Belongs to the UPF0149 family
MS6198_RS10590	COG3012	SEC-C Motif Domain Protein
MS6198_RS10645	COG2197	response regulator
MS6198_RS10660	COG2197	response regulator
MS6198_RS10665	COG1126	abc transporter atp-binding protein
MS6198_RS10670	COG0765	amino acid transport
MS6198_RS10680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS6198_RS10690	COG1191	sigma factor activity
MS6198_RS10700	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MS6198_RS10705	COG1516	flagellar protein fliS
MS6198_RS10715	COG0366	Alpha amylase catalytic
MS6198_RS10725	COG2391	methyltransferase activity
MS6198_RS10730	COG0425	Belongs to the sulfur carrier protein TusA family
MS6198_RS10735	COG2135	peptidase activity
MS6198_RS10740	COG0454	-acetyltransferase
MS6198_RS10765	COG1766	The M ring may be actively involved in energy transduction
MS6198_RS10770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MS6198_RS10775	COG1317	bacterial-type flagellum organization
MS6198_RS10780	COG1157	protein secretion by the type III secretion system
MS6198_RS10785	COG2882	bacterial-type flagellum organization
MS6198_RS10790	COG3144	bacterial-type flagellum assembly
MS6198_RS10795	COG1580	Controls the rotational direction of flagella during chemotaxis
MS6198_RS10800	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MS6198_RS10805	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MS6198_RS10810	COG3190	flagellar
MS6198_RS10815	COG1338	Plays a role in the flagellum-specific transport system
MS6198_RS10820	COG1987	bacterial-type flagellum assembly
MS6198_RS10825	COG1684	flagellar biosynthetic protein fliR
MS6198_RS10830	COG2197	response regulator
MS6198_RS10850	COG3706	GGDEF domain
MS6198_RS10855	COG5475	Uncharacterized small protein (DUF2158)
MS6198_RS10860	COG2354	Protein conserved in bacteria
MS6198_RS10865	COG0697	spore germination
MS6198_RS10870	COG3727	T/G mismatch-specific endonuclease activity
MS6198_RS10875	COG0270	DNA (cytosine-5-)-methyltransferase activity
MS6198_RS10880	COG1418	mRNA catabolic process
MS6198_RS10890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MS6198_RS10905	COG2205	protein histidine kinase activity
MS6198_RS10910	COG0745	RESPONSE REGULATOR receiver
MS6198_RS10915	COG2351	hydroxyisourate hydrolase activity
MS6198_RS10930	COG3443	Belongs to the bacterial solute-binding protein 9 family
MS6198_RS10955	COG0582	viral genome integration into host DNA
MS6198_RS10960	COG1169	isochorismate synthase
MS6198_RS10965	COG2814	Major facilitator Superfamily
MS6198_RS10970	COG1132	(ABC) transporter
MS6198_RS10985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MS6198_RS10985	COG2226	methyltransferase
MS6198_RS10985	COG3433	isochorismatase activity
MS6198_RS11005	COG1021	2,3-dihydroxybenzoate-AMP ligase
MS6198_RS11010	COG4771	TonB-dependent receptor
MS6198_RS11015	COG4932	domain protein
MS6198_RS11015	COG2373	Large extracellular alpha-helical protein
MS6198_RS11015	COG1388	LysM domain
MS6198_RS11020	COG1388	LysM domain
MS6198_RS11020	COG1470	cell adhesion involved in biofilm formation
MS6198_RS11025	COG1388	LysM domain
MS6198_RS11025	COG1470	cell adhesion involved in biofilm formation
MS6198_RS11035	COG0477	Major facilitator Superfamily
MS6198_RS11040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MS6198_RS11045	COG0217	transcriptional regulatory protein
MS6198_RS11055	COG0534	Mate efflux family protein
MS6198_RS11070	COG0583	DNA-binding transcription factor activity
MS6198_RS11080	COG1376	ErfK ybiS ycfS ynhG family protein
MS6198_RS11095	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
MS6198_RS11105	COG4771	TonB-dependent receptor
MS6198_RS11110	COG1475	DNA binding
MS6198_RS11115	COG3969	phosphoadenosine phosphosulfate
MS6198_RS11125	COG0165	Argininosuccinate lyase
MS6198_RS11130	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MS6198_RS11135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MS6198_RS11140	COG2186	Transcriptional regulator
MS6198_RS11145	COG4565	transcriptional regulatory protein
MS6198_RS11150	COG0252	asparaginase activity
MS6198_RS11155	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MS6198_RS11165	COG2195	Cleaves the N-terminal amino acid of tripeptides
MS6198_RS11170	COG3069	C4-dicarboxylate transmembrane transporter activity
MS6198_RS11180	COG1446	asparaginase
MS6198_RS11205	COG1285	pathogenesis
MS6198_RS11220	COG0477	Major facilitator Superfamily
MS6198_RS11250	COG3436	PFAM IS66 Orf2 family protein
MS6198_RS11255	COG2186	Transcriptional regulator
MS6198_RS11260	COG3734	2-keto-3-deoxy-galactonokinase
MS6198_RS11265	COG0800	Aldolase
MS6198_RS11275	COG2271	Major facilitator Superfamily
MS6198_RS11285	COG0583	DNA-binding transcription factor activity
MS6198_RS11295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MS6198_RS11320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS11335	COG1735	metal-dependent hydrolase with the TIM-barrel fold
MS6198_RS11340	COG0405	Gamma-glutamyltransferase
MS6198_RS11400	COG2801	Transposase and inactivated derivatives
MS6198_RS11405	COG2963	transposase activity
MS6198_RS11465	COG2003	Belongs to the UPF0758 family
MS6198_RS11495	COG4917	ethanolamine utilization protein
MS6198_RS11505	COG1289	transmembrane transporter activity
MS6198_RS11515	COG1686	Belongs to the peptidase S11 family
MS6198_RS11520	COG2925	Exonuclease
MS6198_RS11525	COG0425	Belongs to the sulfur carrier protein TusA family
MS6198_RS11530	COG2391	methyltransferase activity
MS6198_RS11535	COG0531	amino acid
MS6198_RS11540	COG0583	DNA-binding transcription factor activity
MS6198_RS11545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MS6198_RS11555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MS6198_RS11565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MS6198_RS11565	COG0131	Imidazoleglycerol-phosphate dehydratase
MS6198_RS11570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MS6198_RS11585	COG0140	phosphoribosyl-ATP diphosphatase activity
MS6198_RS11585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MS6198_RS11590	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
MS6198_RS11595	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MS6198_RS11600	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MS6198_RS11610	COG0463	Glycosyl transferase, family 2
MS6198_RS11625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MS6198_RS11640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MS6198_RS11645	COG1091	dTDP-4-dehydrorhamnose reductase activity
MS6198_RS11650	COG1088	dTDP-glucose 4,6-dehydratase activity
MS6198_RS11655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MS6198_RS11665	COG0438	transferase activity, transferring glycosyl groups
MS6198_RS11670	COG2327	Polysaccharide pyruvyl transferase
MS6198_RS11675	COG2244	polysaccharide biosynthetic process
MS6198_RS11680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MS6198_RS11685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MS6198_RS11690	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MS6198_RS11690	COG0662	Cupin 2, conserved barrel domain protein
MS6198_RS11695	COG0297	glycogen (starch) synthase activity
MS6198_RS11700	COG1051	belongs to the nudix hydrolase family
MS6198_RS11705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MS6198_RS11710	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MS6198_RS11715	COG0110	maltose O-acetyltransferase activity
MS6198_RS11720	COG1216	Glycosyl transferase, family 2
MS6198_RS11730	COG0438	transferase activity, transferring glycosyl groups
MS6198_RS11735	COG1045	serine acetyltransferase
MS6198_RS11740	COG0463	Glycosyl transferase, family 2
MS6198_RS11745	COG0489	protein tyrosine kinase activity
MS6198_RS11745	COG3206	protein involved in exopolysaccharide biosynthesis
MS6198_RS11750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MS6198_RS11755	COG1596	polysaccharide export
MS6198_RS11760	COG1253	flavin adenine dinucleotide binding
MS6198_RS11780	COG2982	Protein involved in outer membrane biogenesis
MS6198_RS11790	COG0572	uridine kinase
MS6198_RS11795	COG5002	protein histidine kinase activity
MS6198_RS11795	COG5001	Diguanylate cyclase
MS6198_RS11795	COG3447	MASE1 domain protein
MS6198_RS11800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MS6198_RS11805	COG0443	Heat shock 70 kDa protein
MS6198_RS11810	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
MS6198_RS11815	COG0631	protein serine/threonine phosphatase activity
MS6198_RS11820	COG4245	von Willebrand factor, type A
MS6198_RS11825	COG3385	transposase activity
MS6198_RS11850	COG2205	protein histidine kinase activity
MS6198_RS11855	COG0745	RESPONSE REGULATOR receiver
MS6198_RS11865	COG3609	addiction module antidote protein, CC2985 family
MS6198_RS11875	COG0826	peptidase U32
MS6198_RS11900	COG1063	alcohol dehydrogenase
MS6198_RS11905	COG3775	system Galactitol-specific IIC component
MS6198_RS11910	COG3414	Phosphotransferase system galactitol-specific IIB component
MS6198_RS11915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS11930	COG1830	Aldolase
MS6198_RS11935	COG2211	Major facilitator Superfamily
MS6198_RS11940	COG1397	ADP-ribosylglycohydrolase
MS6198_RS11945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS11950	COG2188	Transcriptional regulator
MS6198_RS11955	COG3757	hydrolase, family 25
MS6198_RS11960	COG0351	phosphomethylpyrimidine kinase
MS6198_RS11975	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
MS6198_RS11980	COG5455	response to cobalt ion
MS6198_RS11985	COG3539	Fimbrial protein
MS6198_RS11990	COG3188	usher protein
MS6198_RS11995	COG3121	Chaperone
MS6198_RS12000	COG3539	Fimbrial protein
MS6198_RS12015	COG0489	protein tyrosine kinase activity
MS6198_RS12025	COG3831	ATPase activity
MS6198_RS12030	COG3831	ATPase activity
MS6198_RS12045	COG0714	Associated with various cellular activities
MS6198_RS12050	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MS6198_RS12055	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MS6198_RS12060	COG4715	Zinc finger, swim domain protein
MS6198_RS12065	COG4808	Protein conserved in bacteria
MS6198_RS12070	COG4807	Protein conserved in bacteria
MS6198_RS12075	COG3279	Response regulator of the LytR AlgR family
MS6198_RS12080	COG3275	phosphorelay sensor kinase activity
MS6198_RS12085	COG0789	Transcriptional regulator
MS6198_RS12095	COG1174	glycine betaine transport
MS6198_RS12100	COG1125	glycine betaine transport
MS6198_RS12105	COG1174	glycine betaine transport
MS6198_RS12110	COG1732	Glycine betaine
MS6198_RS12115	COG1472	Belongs to the glycosyl hydrolase 3 family
MS6198_RS12120	COG0277	FAD linked oxidase domain protein
MS6198_RS12125	COG1686	Belongs to the peptidase S11 family
MS6198_RS12135	COG0586	Pfam SNARE associated Golgi protein
MS6198_RS12140	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS12155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MS6198_RS12165	COG1346	cytolysis
MS6198_RS12175	COG2949	membrane
MS6198_RS12185	COG0493	'glutamate synthase
MS6198_RS12190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MS6198_RS12190	COG0167	dihydroorotate dehydrogenase activity
MS6198_RS12195	COG4211	Belongs to the binding-protein-dependent transport system permease family
MS6198_RS12205	COG1879	ABC-type sugar transport system periplasmic component
MS6198_RS12210	COG1609	Transcriptional regulator
MS6198_RS12220	COG2311	Membrane
MS6198_RS12240	COG4771	TonB-dependent receptor
MS6198_RS12250	COG0833	amino acid
MS6198_RS12255	COG0583	DNA-binding transcription factor activity
MS6198_RS12260	COG2855	membrane
MS6198_RS12270	COG1522	sequence-specific DNA binding
MS6198_RS12270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS12275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MS6198_RS12285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MS6198_RS12290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MS6198_RS12295	COG2313	pseudouridylate synthase activity
MS6198_RS12300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS12305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
MS6198_RS12305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS12305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS12310	COG1105	Belongs to the carbohydrate kinase PfkB family
MS6198_RS12315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS12315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS12320	COG2814	Major facilitator Superfamily
MS6198_RS12335	COG0246	Mannitol dehydrogenase
MS6198_RS12340	COG0523	cobalamin synthesis protein
MS6198_RS12345	COG0671	phosphoesterase, PA-phosphatase related
MS6198_RS12350	COG0791	NLP P60 protein
MS6198_RS12355	COG2200	EAL domain
MS6198_RS12360	COG4166	transmembrane transport
MS6198_RS12365	COG4174	ABC transporter (Permease)
MS6198_RS12370	COG4239	(ABC) transporter, permease
MS6198_RS12375	COG4172	Belongs to the ABC transporter superfamily
MS6198_RS12385	COG2814	Major facilitator Superfamily
MS6198_RS12390	COG1187	pseudouridine synthase activity
MS6198_RS12395	COG1061	Type III restriction enzyme res subunit
MS6198_RS12415	COG3083	sulfuric ester hydrolase activity
MS6198_RS12425	COG3468	outer membrane autotransporter barrel domain protein
MS6198_RS12435	COG2197	response regulator
MS6198_RS12440	COG4235	cytochrome complex assembly
MS6198_RS12440	COG3088	subunit of a heme lyase
MS6198_RS12445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MS6198_RS12450	COG1138	Cytochrome C-type biogenesis protein
MS6198_RS12460	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MS6198_RS12465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MS6198_RS12470	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MS6198_RS12475	COG4133	protoheme IX ABC transporter activity
MS6198_RS12480	COG3005	denitrification pathway
MS6198_RS12485	COG3043	anaerobic respiration
MS6198_RS12490	COG0348	domain, Protein
MS6198_RS12495	COG0437	4 iron, 4 sulfur cluster binding
MS6198_RS12505	COG3062	negative regulation of establishment of protein localization
MS6198_RS12510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS12510	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS12530	COG4615	Cyclic peptide transporter
MS6198_RS12535	COG3145	DNA-N1-methyladenine dioxygenase activity
MS6198_RS12540	COG2169	Transcriptional regulator
MS6198_RS12540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MS6198_RS12545	COG1477	protein flavinylation
MS6198_RS12550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MS6198_RS12565	COG2198	Histidine kinase
MS6198_RS12565	COG0642	Histidine kinase
MS6198_RS12570	COG2197	response regulator
MS6198_RS12575	COG0784	Response regulator, receiver
MS6198_RS12575	COG2205	protein histidine kinase activity
MS6198_RS12580	COG3852	Histidine kinase
MS6198_RS12585	COG2204	response regulator
MS6198_RS12590	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MS6198_RS12595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MS6198_RS12600	COG2031	fatty acid transporter
MS6198_RS12605	COG0183	Belongs to the thiolase family
MS6198_RS12610	COG4676	Protein conserved in bacteria
MS6198_RS12615	COG5445	Predicted secreted protein (DUF2300)
MS6198_RS12625	COG3234	Protein of unknown function (DUF1175)
MS6198_RS12630	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
MS6198_RS12635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MS6198_RS12645	COG3468	outer membrane autotransporter barrel domain protein
MS6198_RS12655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MS6198_RS12660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MS6198_RS12665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS6198_RS12670	COG3642	lipopolysaccharide core region biosynthetic process
MS6198_RS12675	COG2814	Major facilitator Superfamily
MS6198_RS12680	COG0583	DNA-binding transcription factor activity
MS6198_RS12685	COG0584	glycerophosphoryl diester phosphodiesterase
MS6198_RS12690	COG2271	Major facilitator Superfamily
MS6198_RS12695	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MS6198_RS12705	COG0247	lactate metabolic process
MS6198_RS12710	COG5464	transposase or invertase
MS6198_RS12725	COG2271	Major facilitator Superfamily
MS6198_RS12735	COG1414	Transcriptional regulator
MS6198_RS12800	COG0318	PFAM AMP-dependent synthetase and ligase
MS6198_RS12810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MS6198_RS12825	COG1169	isochorismate synthase
MS6198_RS12830	COG4575	ribosome binding
MS6198_RS12835	COG2153	protein acetylation
MS6198_RS12845	COG5160	protein modification by small protein removal
MS6198_RS12850	COG2304	oxidoreductase activity
MS6198_RS12855	COG2234	aminopeptidase activity
MS6198_RS12870	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MS6198_RS12875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MS6198_RS12885	COG0839	Belongs to the complex I subunit 6 family
MS6198_RS12900	COG1034	ATP synthesis coupled electron transport
MS6198_RS12905	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MS6198_RS12910	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MS6198_RS12930	COG0583	DNA-binding transcription factor activity
MS6198_RS12935	COG0436	Aminotransferase
MS6198_RS12945	COG0471	metal ion transport
MS6198_RS12945	COG0490	domain, Protein
MS6198_RS12950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS6198_RS12970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MS6198_RS12975	COG0857	belongs to the CobB CobQ family
MS6198_RS12975	COG0280	phosphate acetyltransferase
MS6198_RS12980	COG1288	antiporter activity
MS6198_RS12985	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MS6198_RS12990	COG0622	Phosphoesterase
MS6198_RS12995	COG0625	glutathione transferase activity
MS6198_RS13000	COG0625	glutathione transferase activity
MS6198_RS13005	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MS6198_RS13010	COG1090	epimerase
MS6198_RS13015	COG5464	transposase or invertase
MS6198_RS13020	COG4598	ABC transporter
MS6198_RS13025	COG4160	amino acid transport
MS6198_RS13030	COG4215	(ABC) transporter
MS6198_RS13035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS6198_RS13040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS6198_RS13045	COG0163	prenyltransferase activity
MS6198_RS13050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MS6198_RS13055	COG1286	toxin biosynthetic process
MS6198_RS13060	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
MS6198_RS13065	COG0285	dihydrofolate synthase activity
MS6198_RS13075	COG0586	Pfam SNARE associated Golgi protein
MS6198_RS13085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MS6198_RS13100	COG2814	Major facilitator Superfamily
MS6198_RS13105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MS6198_RS13120	COG3101	peptidyl-lysine hydroxylation
MS6198_RS13125	COG0730	response to heat
MS6198_RS13165	COG3539	Fimbrial protein
MS6198_RS13170	COG3539	Fimbrial protein
MS6198_RS13175	COG3539	Fimbrial protein
MS6198_RS13180	COG3121	Chaperone
MS6198_RS13185	COG3188	usher protein
MS6198_RS13190	COG3539	Fimbrial protein
MS6198_RS13195	COG2062	phosphohistidine phosphatase, SixA
MS6198_RS13210	COG3691	Protein conserved in bacteria
MS6198_RS13215	COG2067	long-chain fatty acid transport protein
MS6198_RS13225	COG2853	Lipoprotein
MS6198_RS13230	COG2116	formate transmembrane transporter activity
MS6198_RS13240	COG0583	DNA-binding transcription factor activity
MS6198_RS13245	COG2610	gluconate transmembrane transporter activity
MS6198_RS13255	COG0477	Major facilitator Superfamily
MS6198_RS13260	COG1566	PFAM secretion protein HlyD family protein
MS6198_RS13270	COG2197	response regulator
MS6198_RS13275	COG2198	Histidine kinase
MS6198_RS13275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS6198_RS13275	COG0784	Response regulator, receiver
MS6198_RS13275	COG2205	protein histidine kinase activity
MS6198_RS13280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MS6198_RS13285	COG0679	Auxin Efflux Carrier
MS6198_RS13290	COG0028	Belongs to the TPP enzyme family
MS6198_RS13320	COG1560	Kdo2-lipid A biosynthetic process
MS6198_RS13325	COG0436	Aminotransferase
MS6198_RS13330	COG3275	phosphorelay sensor kinase activity
MS6198_RS13335	COG3279	Response regulator of the LytR AlgR family
MS6198_RS13340	COG2207	Transcriptional regulator
MS6198_RS13350	COG1363	Peptidase, m42
MS6198_RS13355	COG0006	proline dipeptidase activity
MS6198_RS13360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS13365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS13395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MS6198_RS13400	COG2199	diguanylate cyclase activity
MS6198_RS13400	COG2200	EAL domain
MS6198_RS13415	COG3415	Transposase
MS6198_RS13420	COG3415	Transposase
MS6198_RS13425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MS6198_RS13450	COG0583	DNA-binding transcription factor activity
MS6198_RS13460	COG2211	Major facilitator Superfamily
MS6198_RS13465	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MS6198_RS13475	COG0583	DNA-binding transcription factor activity
MS6198_RS13480	COG0385	Bile acid
MS6198_RS13485	COG3530	Putative quorum-sensing-regulated virulence factor
MS6198_RS13505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MS6198_RS13510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS13515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MS6198_RS13520	COG2190	(PTS) system
MS6198_RS13535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MS6198_RS13540	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MS6198_RS13545	COG4208	sulfate ABC transporter
MS6198_RS13550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MS6198_RS13555	COG4150	thiosulfate binding
MS6198_RS13560	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS13575	COG1263	PTS System
MS6198_RS13575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS13580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MS6198_RS13585	COG2837	iron assimilation
MS6198_RS13605	COG0860	N-Acetylmuramoyl-L-alanine amidase
MS6198_RS13615	COG2207	Transcriptional regulator
MS6198_RS13620	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MS6198_RS13625	COG4816	utilization protein
MS6198_RS13635	COG4303	Ethanolamine ammonia lyase large subunit
MS6198_RS13640	COG4819	ethanolamine utilization protein
MS6198_RS13645	COG3192	ethanolamine utilization protein
MS6198_RS13650	COG1454	alcohol dehydrogenase
MS6198_RS13655	COG4820	ethanolamine utilization protein (EutJ)
MS6198_RS13660	COG1012	belongs to the aldehyde dehydrogenase family
MS6198_RS13665	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
MS6198_RS13670	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MS6198_RS13675	COG0280	phosphate acetyltransferase
MS6198_RS13680	COG4812	Cobalamin adenosyltransferase
MS6198_RS13685	COG4766	ethanolamine catabolic process
MS6198_RS13690	COG4917	ethanolamine utilization protein
MS6198_RS13695	COG4810	utilization protein
MS6198_RS13700	COG0438	transferase activity, transferring glycosyl groups
MS6198_RS13710	COG0280	phosphate acetyltransferase
MS6198_RS13710	COG0281	malic enzyme
MS6198_RS13715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MS6198_RS13720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MS6198_RS13725	COG5342	invasion associated locus B
MS6198_RS13735	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS13735	COG0493	'glutamate synthase
MS6198_RS13740	COG3850	Histidine kinase
MS6198_RS13745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS6198_RS13755	COG1393	Belongs to the ArsC family
MS6198_RS13770	COG0400	carboxylic ester hydrolase activity
MS6198_RS13780	COG2321	neutral zinc metallopeptidase
MS6198_RS13795	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MS6198_RS13805	COG2716	regulation of RNA biosynthetic process
MS6198_RS13810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MS6198_RS13815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS13820	COG0651	ATP synthesis coupled electron transport
MS6198_RS13825	COG0650	Formate hydrogenlyase subunit 4
MS6198_RS13830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MS6198_RS13835	COG4237	Hydrogenase 4 membrane
MS6198_RS13840	COG0651	ATP synthesis coupled electron transport
MS6198_RS13845	COG3261	NADH dehydrogenase
MS6198_RS13845	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MS6198_RS13850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MS6198_RS13855	COG3260	NADH ubiquinone oxidoreductase 20
MS6198_RS13865	COG3604	Transcriptional regulator
MS6198_RS13870	COG2116	formate transmembrane transporter activity
MS6198_RS13875	COG0628	permease
MS6198_RS13880	COG4783	chaperone-mediated protein folding
MS6198_RS13885	COG1393	Belongs to the ArsC family
MS6198_RS13895	COG2233	PERMEase
MS6198_RS13910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MS6198_RS13915	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MS6198_RS13920	COG0248	Ppx GppA phosphatase
MS6198_RS13925	COG2200	EAL domain
MS6198_RS13940	COG3133	Outer membrane lipoprotein
MS6198_RS13955	COG0517	IMP dehydrogenase activity
MS6198_RS13955	COG0516	GMP reductase activity
MS6198_RS13980	COG1645	bacterial-type flagellum-dependent swarming motility
MS6198_RS13995	COG2976	Protein conserved in bacteria
MS6198_RS14025	COG4953	penicillin-binding protein 1C
MS6198_RS14030	COG2373	Large extracellular alpha-helical protein
MS6198_RS14035	COG2897	thiosulfate sulfurtransferase activity
MS6198_RS14050	COG2975	iron-sulfur cluster assembly
MS6198_RS14055	COG0633	Ferredoxin
MS6198_RS14075	COG0822	iron-sulfur transferase activity
MS6198_RS14095	COG0483	inositol monophosphate 1-phosphatase activity
MS6198_RS14100	COG1073	alpha beta
MS6198_RS14105	COG3711	transcriptional antiterminator
MS6198_RS14110	COG2814	Major facilitator Superfamily
MS6198_RS14115	COG0583	DNA-binding transcription factor activity
MS6198_RS14120	COG4638	Rieske (2fe-2S)
MS6198_RS14145	COG2259	Doxx family
MS6198_RS14150	COG2017	converts alpha-aldose to the beta-anomer
MS6198_RS14155	COG1063	alcohol dehydrogenase
MS6198_RS14160	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS6198_RS14165	COG1129	ABC transporter
MS6198_RS14170	COG1879	ABC-type sugar transport system periplasmic component
MS6198_RS14175	COG0457	Tetratricopeptide repeat
MS6198_RS14180	COG1940	carbohydrate kinase activity
MS6198_RS14195	COG1017	nitric oxide dioxygenase activity
MS6198_RS14195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS6198_RS14200	COG0347	Belongs to the P(II) protein family
MS6198_RS14205	COG2204	response regulator
MS6198_RS14210	COG3170	Tfp pilus assembly protein FimV
MS6198_RS14215	COG2205	protein histidine kinase activity
MS6198_RS14220	COG0047	phosphoribosylformylglycinamidine synthase activity
MS6198_RS14220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MS6198_RS14230	COG0590	tRNA wobble adenosine to inosine editing
MS6198_RS14235	COG0560	Phosphoserine phosphatase
MS6198_RS14240	COG1737	Transcriptional regulator
MS6198_RS14245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS14265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MS6198_RS14285	COG0681	Belongs to the peptidase S26 family
MS6198_RS14295	COG3086	response to oxidative stress
MS6198_RS14300	COG3026	antisigma factor binding
MS6198_RS14305	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
MS6198_RS14310	COG1595	DNA-templated transcription, initiation
MS6198_RS14320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MS6198_RS14330	COG0513	Belongs to the DEAD box helicase family
MS6198_RS14335	COG0583	DNA-binding transcription factor activity
MS6198_RS14355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MS6198_RS14365	COG3118	belongs to the thioredoxin family
MS6198_RS14370	COG3148	PFAM DTW domain containing protein
MS6198_RS14375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS6198_RS14375	COG0045	succinate-CoA ligase (ADP-forming) activity
MS6198_RS14375	COG1042	CoA-binding domain protein
MS6198_RS14380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MS6198_RS14385	COG5544	Lipoprotein
MS6198_RS14390	COG0477	Major facilitator Superfamily
MS6198_RS14420	COG0542	response to heat
MS6198_RS14430	COG0564	pseudouridine synthase activity
MS6198_RS14435	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS6198_RS14440	COG3385	transposase activity
MS6198_RS14450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MS6198_RS14455	COG1605	Chorismate mutase
MS6198_RS14455	COG0077	Prephenate dehydratase
MS6198_RS14460	COG0287	Prephenate dehydrogenase
MS6198_RS14460	COG1605	Chorismate mutase
MS6198_RS14465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MS6198_RS14480	COG2199	diguanylate cyclase activity
MS6198_RS14485	COG2885	chlorophyll binding
MS6198_RS14510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MS6198_RS14515	COG4137	Cytochrome C assembly protein
MS6198_RS14520	COG4536	flavin adenine dinucleotide binding
MS6198_RS14535	COG0497	DNA recombination
MS6198_RS14540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS6198_RS14550	COG2867	negative regulation of translational initiation
MS6198_RS14565	COG3468	outer membrane autotransporter barrel domain protein
MS6198_RS14595	COG0579	oxidoreductase
MS6198_RS14600	COG1012	belongs to the aldehyde dehydrogenase family
MS6198_RS14605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MS6198_RS14610	COG1113	amino acid transport
MS6198_RS14615	COG1802	Transcriptional regulator
MS6198_RS14620	COG1652	LysM domain
MS6198_RS14625	COG0401	homolog of Blt101
MS6198_RS14630	COG0640	Transcriptional regulator
MS6198_RS14635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MS6198_RS14640	COG2916	Histone family protein nucleoid-structuring protein H-NS
MS6198_RS14655	COG4575	ribosome binding
MS6198_RS14665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS6198_RS14670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MS6198_RS14680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MS6198_RS14685	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MS6198_RS14690	COG4175	Glycine betaine
MS6198_RS14695	COG4176	ABC-type proline glycine betaine transport system permease component
MS6198_RS14700	COG2113	Glycine betaine
MS6198_RS14705	COG2814	Major facilitator Superfamily
MS6198_RS14710	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MS6198_RS14720	COG1846	Transcriptional regulator
MS6198_RS14725	COG1566	PFAM secretion protein HlyD family protein
MS6198_RS14730	COG2814	Major facilitator Superfamily
MS6198_RS14745	COG1238	metal cluster binding
MS6198_RS14750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS6198_RS14780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MS6198_RS14805	COG1546	Belongs to the CinA family
MS6198_RS14810	COG2951	lytic endotransglycosylase activity
MS6198_RS14815	COG3730	PTS system glucitol sorbitol-specific
MS6198_RS14820	COG3732	PTS system glucitol sorbitol-specific
MS6198_RS14830	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS14835	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS14840	COG1349	DNA-binding transcription factor activity
MS6198_RS14845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MS6198_RS14845	COG0517	IMP dehydrogenase activity
MS6198_RS14865	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MS6198_RS14870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS14875	COG1609	Transcriptional regulator
MS6198_RS14880	COG1263	PTS System
MS6198_RS14880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS14885	COG2723	6-phospho-beta-galactosidase activity
MS6198_RS14890	COG5499	transcription regulator containing HTH domain
MS6198_RS14895	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MS6198_RS14905	COG3260	NADH ubiquinone oxidoreductase 20
MS6198_RS14910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MS6198_RS14915	COG3261	NADH dehydrogenase
MS6198_RS14915	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MS6198_RS14920	COG0650	Formate hydrogenlyase subunit 4
MS6198_RS14925	COG0651	ATP synthesis coupled electron transport
MS6198_RS14930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS14945	COG0375	protein maturation
MS6198_RS14950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MS6198_RS14955	COG0298	carbon dioxide binding
MS6198_RS14960	COG0409	Hydrogenase expression formation protein
MS6198_RS14965	COG0309	Hydrogenase expression formation protein (HypE)
MS6198_RS14970	COG3604	Transcriptional regulator
MS6198_RS14990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MS6198_RS15000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MS6198_RS15015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MS6198_RS15020	COG4942	peptidase
MS6198_RS15020	COG1388	LysM domain
MS6198_RS15075	COG2234	aminopeptidase activity
MS6198_RS15080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MS6198_RS15085	COG1518	maintenance of DNA repeat elements
MS6198_RS15100	COG1857	crispr-associated protein
MS6198_RS15115	COG1203	CRISPR-associated helicase, Cas3
MS6198_RS15135	COG0720	synthase
MS6198_RS15140	COG0644	oxidoreductase
MS6198_RS15145	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MS6198_RS15150	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MS6198_RS15155	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MS6198_RS15160	COG2086	electron transfer activity
MS6198_RS15165	COG0477	Major facilitator Superfamily
MS6198_RS15170	COG0277	FAD linked oxidase domain protein
MS6198_RS15175	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS15180	COG2223	nitrite transmembrane transporter activity
MS6198_RS15185	COG1070	Carbohydrate kinase
MS6198_RS15190	COG0602	queuosine metabolic process
MS6198_RS15200	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MS6198_RS15215	COG3956	TIGRFAM MazG family protein
MS6198_RS15220	COG2337	Toxic component of a toxin-antitoxin (TA) module
MS6198_RS15225	COG2336	PFAM SpoVT AbrB
MS6198_RS15230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MS6198_RS15240	COG3850	Histidine kinase
MS6198_RS15240	COG2205	protein histidine kinase activity
MS6198_RS15240	COG4999	Histidine kinase
MS6198_RS15240	COG3437	response regulator, receiver
MS6198_RS15245	COG4948	Mandelate Racemase Muconate Lactonizing
MS6198_RS15250	COG4948	Mandelate Racemase Muconate Lactonizing
MS6198_RS15255	COG2271	Major facilitator Superfamily
MS6198_RS15260	COG0716	FMN binding
MS6198_RS15265	COG0564	pseudouridine synthase activity
MS6198_RS15270	COG3098	single-species biofilm formation
MS6198_RS15290	COG1611	Belongs to the LOG family
MS6198_RS15295	COG0814	amino acid
MS6198_RS15300	COG1760	l-serine dehydratase
MS6198_RS15310	COG1454	alcohol dehydrogenase
MS6198_RS15315	COG0235	Class ii aldolase
MS6198_RS15320	COG0738	Major facilitator superfamily
MS6198_RS15330	COG1070	Carbohydrate kinase
MS6198_RS15340	COG1349	DNA-binding transcription factor activity
MS6198_RS15350	COG2363	Small membrane protein
MS6198_RS15355	COG0583	DNA-binding transcription factor activity
MS6198_RS15365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MS6198_RS15370	COG2166	iron-sulfur cluster assembly
MS6198_RS15375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MS6198_RS15380	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MS6198_RS15410	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MS6198_RS15415	COG1263	PTS System
MS6198_RS15415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS15420	COG3711	transcriptional antiterminator
MS6198_RS15425	COG0860	N-Acetylmuramoyl-L-alanine amidase
MS6198_RS15430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MS6198_RS15430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MS6198_RS15435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MS6198_RS15440	COG1074	ATP-dependent DNA helicase activity
MS6198_RS15450	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MS6198_RS15455	COG4967	type IV pilus modification protein PilV
MS6198_RS15465	COG4795	General secretion pathway protein
MS6198_RS15470	COG2165	general secretion pathway protein
MS6198_RS15485	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
MS6198_RS15510	COG0861	Integral membrane protein TerC family
MS6198_RS15520	COG0667	Aldo Keto reductase
MS6198_RS15535	COG1609	Transcriptional regulator
MS6198_RS15545	COG0583	DNA-binding transcription factor activity
MS6198_RS15550	COG1794	racemase activity, acting on amino acids and derivatives
MS6198_RS15555	COG2814	Major facilitator Superfamily
MS6198_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS15570	COG0183	Belongs to the thiolase family
MS6198_RS15575	COG0814	amino acid
MS6198_RS15580	COG2771	luxR family
MS6198_RS15585	COG3710	Transcriptional regulator
MS6198_RS15615	COG0457	Tetratricopeptide repeat
MS6198_RS15620	COG0457	Tetratricopeptide repeat
MS6198_RS15620	COG3710	Transcriptional regulator
MS6198_RS15630	COG0741	lytic transglycosylase activity
MS6198_RS15635	COG2197	response regulator
MS6198_RS15740	COG2207	Transcriptional regulator
MS6198_RS15750	COG3387	PFAM Glycoside hydrolase 15-related
MS6198_RS15760	COG4942	peptidase
MS6198_RS15770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MS6198_RS15775	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MS6198_RS15780	COG2080	2 iron, 2 sulfur cluster binding
MS6198_RS15785	COG3829	transcription factor binding
MS6198_RS15790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MS6198_RS15795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MS6198_RS15800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MS6198_RS15810	COG0549	Belongs to the carbamate kinase family
MS6198_RS15815	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MS6198_RS15815	COG3608	succinylglutamate desuccinylase aspartoacylase
MS6198_RS15820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MS6198_RS15825	COG2068	MobA-Related Protein
MS6198_RS15830	COG0493	'glutamate synthase
MS6198_RS15830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS15835	COG0402	S-adenosylhomocysteine deaminase activity
MS6198_RS15840	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MS6198_RS15845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MS6198_RS15845	COG2080	2 iron, 2 sulfur cluster binding
MS6198_RS15850	COG2233	PERMEase
MS6198_RS15855	COG0402	S-adenosylhomocysteine deaminase activity
MS6198_RS15860	COG2252	PERMEase
MS6198_RS15865	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS15870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS15870	COG0493	'glutamate synthase
MS6198_RS15895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MS6198_RS15905	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MS6198_RS15910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MS6198_RS15915	COG4974	Belongs to the 'phage' integrase family
MS6198_RS15920	COG0716	FMN binding
MS6198_RS15930	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MS6198_RS15940	COG1272	protein, Hemolysin III
MS6198_RS15950	COG2723	6-phospho-beta-galactosidase activity
MS6198_RS15970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS6198_RS15975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS6198_RS15980	COG0006	proline dipeptidase activity
MS6198_RS16000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MS6198_RS16010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MS6198_RS16025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MS6198_RS16040	COG1662	PFAM IS1 transposase
MS6198_RS16040	COG3677	Transposase
MS6198_RS16045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS6198_RS16055	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MS6198_RS16055	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MS6198_RS16060	COG1703	isobutyryl-CoA mutase activity
MS6198_RS16065	COG1024	Enoyl-CoA hydratase
MS6198_RS16070	COG0427	acetyl-CoA hydrolase
MS6198_RS16075	COG0583	DNA-binding transcription factor activity
MS6198_RS16080	COG2968	Membrane
MS6198_RS16085	COG1279	arginine transmembrane transporter activity
MS6198_RS16090	COG0668	transmembrane transport
MS6198_RS16095	COG0191	fructose-bisphosphate aldolase activity
MS6198_RS16110	COG1072	(Pantothenic acid kinase))
MS6198_RS16120	COG1494	fructose-1,6-bisphosphatase
MS6198_RS16125	COG1063	alcohol dehydrogenase
MS6198_RS16130	COG2213	PTS system mannitol-specific
MS6198_RS16135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS16140	COG0330	HflC and HflK could
MS6198_RS16145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MS6198_RS16150	COG0501	Belongs to the peptidase M48B family
MS6198_RS16165	COG1166	arginine decarboxylase activity
MS6198_RS16190	COG2814	Major facilitator Superfamily
MS6198_RS16200	COG2356	endonuclease I
MS6198_RS16205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MS6198_RS16210	COG0189	ligase activity
MS6198_RS16225	COG2805	Type II/IV secretion system protein
MS6198_RS16230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MS6198_RS16235	COG0762	integral membrane protein
MS6198_RS16245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MS6198_RS16250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MS6198_RS16255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MS6198_RS16260	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MS6198_RS16275	COG0252	asparaginase activity
MS6198_RS16290	COG3171	Protein conserved in bacteria
MS6198_RS16300	COG1194	a g-specific adenine glycosylase
MS6198_RS16315	COG2211	Major facilitator Superfamily
MS6198_RS16320	COG1982	Orn Lys Arg decarboxylase major
MS6198_RS16325	COG1811	Na channel or pump
MS6198_RS16335	COG0582	viral genome integration into host DNA
MS6198_RS16385	COG1982	Orn Lys Arg decarboxylase major
MS6198_RS16390	COG0531	amino acid
MS6198_RS16410	COG0604	alcohol dehydrogenase
MS6198_RS16415	COG2963	transposase activity
MS6198_RS16480	COG4869	propanediol catabolic process
MS6198_RS16485	COG4820	ethanolamine utilization protein (EutJ)
MS6198_RS16520	COG1012	belongs to the aldehyde dehydrogenase family
MS6198_RS16530	COG0693	protein deglycase activity
MS6198_RS16535	COG1882	Formate acetyltransferase
MS6198_RS16540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MS6198_RS16555	COG3344	reverse transcriptase
MS6198_RS16560	COG2972	Histidine kinase
MS6198_RS16565	COG2207	Transcriptional regulator
MS6198_RS16570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MS6198_RS16580	COG1309	transcriptional regulator
MS6198_RS16610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS16610	COG1522	sequence-specific DNA binding
MS6198_RS16615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MS6198_RS16620	COG2313	pseudouridylate synthase activity
MS6198_RS16625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS16630	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MS6198_RS16660	COG3596	GTP binding
MS6198_RS16670	COG2378	regulation of single-species biofilm formation
MS6198_RS16695	COG2003	Belongs to the UPF0758 family
MS6198_RS16790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MS6198_RS16810	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
MS6198_RS16840	COG2165	general secretion pathway protein
MS6198_RS16845	COG1459	type II secretion system
MS6198_RS16850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MS6198_RS16875	COG3064	Membrane
MS6198_RS16885	COG1620	l-lactate permease
MS6198_RS16890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MS6198_RS16895	COG3193	protein, possibly involved in utilization of glycolate and propanediol
MS6198_RS16900	COG0247	lactate metabolic process
MS6198_RS16905	COG0277	FAD linked oxidase domain protein
MS6198_RS16910	COG0277	FAD linked oxidase domain protein
MS6198_RS16915	COG2186	Transcriptional regulator
MS6198_RS16920	COG0456	acetyltransferase
MS6198_RS16925	COG0318	PFAM AMP-dependent synthetase and ligase
MS6198_RS16935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MS6198_RS16940	COG0156	8-amino-7-oxononanoate synthase activity
MS6198_RS16950	COG0795	lipopolysaccharide-transporting ATPase activity
MS6198_RS16955	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
MS6198_RS16965	COG2244	polysaccharide biosynthetic process
MS6198_RS16970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MS6198_RS16975	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MS6198_RS16980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MS6198_RS16985	COG0306	phosphate transporter
MS6198_RS16990	COG0754	glutathionylspermidine amidase activity
MS6198_RS16995	COG0625	glutathione transferase activity
MS6198_RS17000	COG2801	Transposase and inactivated derivatives
MS6198_RS17010	COG0298	carbon dioxide binding
MS6198_RS17020	COG1773	rubredoxin
MS6198_RS17025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MS6198_RS17030	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
MS6198_RS17035	COG5557	Pfam Polysulphide reductase, NrfD
MS6198_RS17040	COG0437	4 iron, 4 sulfur cluster binding
MS6198_RS17045	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
MS6198_RS17065	COG0667	Aldo Keto reductase
MS6198_RS17075	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS17080	COG0848	biopolymer transport protein
MS6198_RS17085	COG0811	peptide transport
MS6198_RS17095	COG0626	cystathionine gamma-synthase activity
MS6198_RS17100	COG0586	Pfam SNARE associated Golgi protein
MS6198_RS17105	COG2207	Transcriptional regulator
MS6198_RS17115	COG1979	alcohol dehydrogenase
MS6198_RS17120	COG0656	L-ascorbic acid biosynthetic process
MS6198_RS17130	COG4238	major outer membrane lipoprotein
MS6198_RS17145	COG1032	radical SAM domain protein
MS6198_RS17150	COG2186	Transcriptional regulator
MS6198_RS17155	COG0246	Mannitol dehydrogenase
MS6198_RS17160	COG1063	alcohol dehydrogenase
MS6198_RS17165	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MS6198_RS17185	COG2132	Multicopper oxidase
MS6198_RS17190	COG0204	Acyl-transferase
MS6198_RS17195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MS6198_RS17200	COG4166	transmembrane transport
MS6198_RS17205	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MS6198_RS17210	COG3111	PFAM Bacterial OB fold (BOF) protein
MS6198_RS17215	COG0745	RESPONSE REGULATOR receiver
MS6198_RS17220	COG0642	Histidine kinase
MS6198_RS17230	COG2249	NAD(P)H dehydrogenase (quinone) activity
MS6198_RS17235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MS6198_RS17240	COG1737	Transcriptional regulator
MS6198_RS17250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS6198_RS17255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS6198_RS17260	COG1120	ATPase activity
MS6198_RS17265	COG4774	siderophore transport
MS6198_RS17270	COG0187	DNA topoisomerase II activity
MS6198_RS17275	COG3150	esterase
MS6198_RS17280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MS6198_RS17285	COG3151	Protein conserved in bacteria
MS6198_RS17290	COG0494	nUDIX hydrolase
MS6198_RS17295	COG1538	Outer membrane efflux protein
MS6198_RS17310	COG0754	glutathionylspermidine amidase activity
MS6198_RS17320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MS6198_RS17330	COG3384	dioxygenase
MS6198_RS17360	COG1585	Membrane protein implicated in regulation of membrane protease activity
MS6198_RS17365	COG2268	Band 7 protein
MS6198_RS17385	COG3025	triphosphatase activity
MS6198_RS17395	COG4991	sh3 domain protein
MS6198_RS17410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MS6198_RS17425	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MS6198_RS17430	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MS6198_RS17445	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MS6198_RS17450	COG0358	DNA primase activity
MS6198_RS17455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MS6198_RS17470	COG2375	cellular response to nickel ion
MS6198_RS17475	COG1695	Transcriptional regulator
MS6198_RS17480	COG0840	transmembrane signaling receptor activity
MS6198_RS17490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MS6198_RS17495	COG1609	Transcriptional regulator
MS6198_RS17500	COG3250	beta-galactosidase activity
MS6198_RS17505	COG2731	YhcH YjgK YiaL family protein
MS6198_RS17510	COG0531	amino acid
MS6198_RS17520	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
MS6198_RS17520	COG3408	Glycogen debranching enzyme
MS6198_RS17525	COG1902	pentaerythritol trinitrate reductase activity
MS6198_RS17525	COG0446	pyridine nucleotide-disulphide oxidoreductase
MS6198_RS17530	COG5499	transcription regulator containing HTH domain
MS6198_RS17550	COG1451	nucleotide metabolic process
MS6198_RS17555	COG2949	membrane
MS6198_RS17560	COG0673	inositol 2-dehydrogenase activity
MS6198_RS17565	COG0861	Integral membrane protein TerC family
MS6198_RS17570	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MS6198_RS17580	COG2721	sulfolactate sulfo-lyase activity
MS6198_RS17590	COG2271	Major facilitator Superfamily
MS6198_RS17615	COG2186	Transcriptional regulator
MS6198_RS17620	COG0586	Pfam SNARE associated Golgi protein
MS6198_RS17630	COG1422	Protein of unknown function (DUF1090)
MS6198_RS17635	COG4575	ribosome binding
MS6198_RS17640	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
MS6198_RS17650	COG2259	Doxx family
MS6198_RS17655	COG0435	Glutathione S-transferase
MS6198_RS17660	COG3152	Membrane
MS6198_RS17665	COG3152	Membrane
MS6198_RS17670	COG0583	DNA-binding transcription factor activity
MS6198_RS17675	COG1741	Belongs to the pirin family
MS6198_RS17690	COG0814	amino acid
MS6198_RS17695	COG1760	l-serine dehydratase
MS6198_RS17700	COG0251	oxidation-reduction process
MS6198_RS17705	COG1882	Formate acetyltransferase
MS6198_RS17710	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MS6198_RS17720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MS6198_RS17725	COG0583	DNA-binding transcription factor activity
MS6198_RS17750	COG1929	Belongs to the glycerate kinase type-1 family
MS6198_RS17755	COG2084	Dehydrogenase
MS6198_RS17765	COG2271	Major facilitator Superfamily
MS6198_RS17770	COG2721	sulfolactate sulfo-lyase activity
MS6198_RS17775	COG2002	toxin-antitoxin pair type II binding
MS6198_RS17785	COG1349	DNA-binding transcription factor activity
MS6198_RS17795	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS17805	COG3716	PTS system mannose fructose sorbose family IID component
MS6198_RS17810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS17815	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MS6198_RS17820	COG2222	sugar isomerase
MS6198_RS17830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS17840	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS17845	COG3715	PTS system
MS6198_RS17850	COG3716	PTS system mannose fructose sorbose family IID component
MS6198_RS17855	COG0363	glucosamine-6-phosphate deaminase activity
MS6198_RS17860	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MS6198_RS17880	COG2823	Periplasmic or secreted lipoprotein
MS6198_RS17885	COG0701	Predicted permease
MS6198_RS17890	COG0702	epimerase
MS6198_RS17895	COG0693	protein deglycase activity
MS6198_RS17910	COG3153	acetyltransferase
MS6198_RS17915	COG3154	lipid carrier protein
MS6198_RS17920	COG0826	peptidase U32
MS6198_RS17925	COG0826	peptidase U32
MS6198_RS17930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS6198_RS17935	COG0814	amino acid
MS6198_RS17945	COG0513	Belongs to the DEAD box helicase family
MS6198_RS17980	COG0195	Participates in both transcription termination and antitermination
MS6198_RS18000	COG2194	sulfuric ester hydrolase activity
MS6198_RS18010	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MS6198_RS18020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MS6198_RS18025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MS6198_RS18035	COG1534	Rna-binding protein
MS6198_RS18040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MS6198_RS18045	COG2027	D-alanyl-D-alanine carboxypeptidase
MS6198_RS18055	COG0697	spore germination
MS6198_RS18070	COG0142	geranyltranstransferase activity
MS6198_RS18075	COG3423	Transcriptional regulator
MS6198_RS18085	COG5007	Belongs to the BolA IbaG family
MS6198_RS18090	COG3113	response to antibiotic
MS6198_RS18095	COG2854	intermembrane phospholipid transfer
MS6198_RS18100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MS6198_RS18105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MS6198_RS18110	COG1127	ABC transporter
MS6198_RS18115	COG0530	calcium, potassium:sodium antiporter activity
MS6198_RS18120	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MS6198_RS18120	COG0517	IMP dehydrogenase activity
MS6198_RS18125	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MS6198_RS18130	COG3117	lipopolysaccharide transmembrane transporter activity
MS6198_RS18135	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MS6198_RS18140	COG1137	ATPase activity
MS6198_RS18145	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MS6198_RS18150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MS6198_RS18165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS18170	COG0515	serine threonine protein kinase
MS6198_RS18180	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MS6198_RS18185	COG5002	protein histidine kinase activity
MS6198_RS18185	COG2198	Histidine kinase
MS6198_RS18185	COG0784	Response regulator, receiver
MS6198_RS18190	COG1242	4 iron, 4 sulfur cluster binding
MS6198_RS18195	COG0067	glutamate synthase
MS6198_RS18195	COG0069	glutamate synthase activity
MS6198_RS18195	COG0070	glutamate synthase
MS6198_RS18200	COG0493	'glutamate synthase
MS6198_RS18205	COG4804	nuclease activity
MS6198_RS18210	COG2731	YhcH YjgK YiaL family protein
MS6198_RS18240	COG3069	C4-dicarboxylate transmembrane transporter activity
MS6198_RS18245	COG2969	positive regulation of protein catabolic process
MS6198_RS18250	COG0625	glutathione transferase activity
MS6198_RS18265	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MS6198_RS18270	COG3105	Protein conserved in bacteria
MS6198_RS18275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MS6198_RS18280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MS6198_RS18300	COG2732	(Barnase) inhibitor
MS6198_RS18320	COG0583	DNA-binding transcription factor activity
MS6198_RS18325	COG0312	modulator of DNA gyrase
MS6198_RS18330	COG3164	Protein of unknown function
MS6198_RS18335	COG1530	ribonuclease E activity
MS6198_RS18345	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MS6198_RS18350	COG1792	Involved in formation and maintenance of cell shape
MS6198_RS18355	COG1077	Cell shape determining protein MreB Mrl
MS6198_RS18365	COG2200	EAL domain
MS6198_RS18365	COG2199	diguanylate cyclase activity
MS6198_RS18370	COG0604	alcohol dehydrogenase
MS6198_RS18385	COG0511	ligase activity, forming carbon-carbon bonds
MS6198_RS18390	COG0439	Biotin carboxylase
MS6198_RS18400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS18405	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS6198_RS18410	COG1129	ABC transporter
MS6198_RS18415	COG1879	ABC-type sugar transport system periplasmic component
MS6198_RS18425	COG1349	DNA-binding transcription factor activity
MS6198_RS18430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS18435	COG3924	membrane
MS6198_RS18440	COG4145	pantothenate transmembrane transporter activity
MS6198_RS18450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MS6198_RS18465	COG4626	Terminase
MS6198_RS18465	COG1802	Transcriptional regulator
MS6198_RS18575	COG1309	transcriptional regulator
MS6198_RS18580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS6198_RS18585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS6198_RS18600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS6198_RS18605	COG4597	amino acid ABC transporter
MS6198_RS18610	COG0765	amino acid transport
MS6198_RS18615	COG1126	abc transporter atp-binding protein
MS6198_RS18655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MS6198_RS18675	COG0551	DNA topoisomerase type I activity
MS6198_RS18685	COG0758	DNA mediated transformation
MS6198_RS18705	COG0569	domain protein
MS6198_RS18715	COG3036	rescue of stalled ribosome
MS6198_RS18720	COG0789	Transcriptional regulator
MS6198_RS18760	COG0201	protein transport
MS6198_RS18850	COG0089	rRNA binding
MS6198_RS18925	COG2964	Protein conserved in bacteria
MS6198_RS18930	COG0545	Peptidyl-prolyl cis-trans isomerase
MS6198_RS18940	COG1047	Peptidyl-prolyl cis-trans
MS6198_RS18945	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MS6198_RS18960	COG0488	(ABC) transporter
MS6198_RS18965	COG0429	hydrolase of the alpha beta-hydrolase fold
MS6198_RS18975	COG3954	Phosphoribulokinase
MS6198_RS18980	COG1765	OsmC-like protein
MS6198_RS18990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MS6198_RS18995	COG1289	transmembrane transporter activity
MS6198_RS19000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MS6198_RS19005	COG0512	Glutamine amidotransferase of anthranilate synthase
MS6198_RS19010	COG2184	nucleotidyltransferase activity
MS6198_RS19020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MS6198_RS19030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MS6198_RS19035	COG2146	nitrite reductase [NAD(P)H] activity
MS6198_RS19040	COG2116	formate transmembrane transporter activity
MS6198_RS19055	COG0626	cystathionine gamma-synthase activity
MS6198_RS19070	COG1735	metal-dependent hydrolase with the TIM-barrel fold
MS6198_RS19075	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MS6198_RS19080	COG3457	Alanine racemase
MS6198_RS19090	COG2188	Transcriptional regulator
MS6198_RS19095	COG0180	Tryptophanyl-tRNA synthetase
MS6198_RS19105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MS6198_RS19110	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MS6198_RS19115	COG3266	domain, Protein
MS6198_RS19130	COG4796	Type ii and iii secretion system protein
MS6198_RS19145	COG3166	PFAM Fimbrial assembly family protein
MS6198_RS19150	COG4972	Pilus assembly protein
MS6198_RS19155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MS6198_RS19160	COG0494	nUDIX hydrolase
MS6198_RS19170	COG1011	Hydrolase
MS6198_RS19175	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MS6198_RS19185	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MS6198_RS19220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MS6198_RS19225	COG2183	response to ionizing radiation
MS6198_RS19230	COG1918	ferrous iron import across plasma membrane
MS6198_RS19235	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MS6198_RS19245	COG5464	transposase or invertase
MS6198_RS19255	COG1040	competence protein
MS6198_RS19265	COG2610	gluconate transmembrane transporter activity
MS6198_RS19270	COG1640	4-alpha-glucanotransferase
MS6198_RS19275	COG0058	SHG alpha-glucan phosphorylase activity
MS6198_RS19290	COG1690	Belongs to the RtcB family
MS6198_RS19295	COG4650	regulator
MS6198_RS19300	COG1349	DNA-binding transcription factor activity
MS6198_RS19315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MS6198_RS19330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MS6198_RS19335	COG0058	SHG alpha-glucan phosphorylase activity
MS6198_RS19355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MS6198_RS19360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MS6198_RS19365	COG2095	MarC family integral membrane protein
MS6198_RS19375	COG0514	ATP-dependent DNA helicase (RecQ)
MS6198_RS19380	COG2610	gluconate transmembrane transporter activity
MS6198_RS19385	COG3265	gluconokinase activity
MS6198_RS19390	COG1609	Transcriptional regulator
MS6198_RS19395	COG1741	Belongs to the pirin family
MS6198_RS19400	COG0673	inositol 2-dehydrogenase activity
MS6198_RS19410	COG1247	-acetyltransferase
MS6198_RS19415	COG0405	Gamma-glutamyltransferase
MS6198_RS19425	COG0584	glycerophosphoryl diester phosphodiesterase
MS6198_RS19440	COG1175	transmembrane transport
MS6198_RS19455	COG0410	ABC transporter
MS6198_RS19460	COG0411	ABC transporter
MS6198_RS19465	COG4177	L-phenylalanine transmembrane transporter activity
MS6198_RS19470	COG0559	Belongs to the binding-protein-dependent transport system permease family
MS6198_RS19475	COG0683	leucine binding
MS6198_RS19480	COG0456	acetyltransferase
MS6198_RS19490	COG0683	leucine binding
MS6198_RS19495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MS6198_RS19500	COG2177	Part of the ABC transporter FtsEX involved in
MS6198_RS19505	COG2884	Cell division ATP-binding protein ftsE
MS6198_RS19510	COG0552	protein localization to endoplasmic reticulum
MS6198_RS19515	COG0742	ribosomal rna small subunit methyltransferase
MS6198_RS19520	COG3776	membrane
MS6198_RS19530	COG3714	YhhN family
MS6198_RS19545	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MS6198_RS19555	COG0477	Major facilitator Superfamily
MS6198_RS19560	COG0628	permease
MS6198_RS19565	COG2091	lysine biosynthetic process via aminoadipic acid
MS6198_RS19570	COG0747	negative chemotaxis
MS6198_RS19575	COG0601	transmembrane transport
MS6198_RS19580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS6198_RS19610	COG0842	Transport permease protein
MS6198_RS19615	COG0842	Transport permease protein
MS6198_RS19615	COG1129	ABC transporter
MS6198_RS19620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS6198_RS19650	COG2081	HI0933 family
MS6198_RS19655	COG0306	phosphate transporter
MS6198_RS19665	COG0589	response to stress
MS6198_RS19670	COG3104	oligopeptide transport
MS6198_RS19680	COG0339	signal peptide processing
MS6198_RS19685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MS6198_RS19690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS6198_RS19705	COG0640	Transcriptional regulator
MS6198_RS19710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MS6198_RS19715	COG1393	Belongs to the ArsC family
MS6198_RS19735	COG3065	identical protein binding
MS6198_RS19740	COG2197	response regulator
MS6198_RS19745	COG3720	iron ion transport
MS6198_RS19750	COG4771	TonB-dependent receptor
MS6198_RS19770	COG3721	Heme iron utilization protein
MS6198_RS19780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS6198_RS19790	COG1285	pathogenesis
MS6198_RS19805	COG3247	response to pH
MS6198_RS19810	COG2771	luxR family
MS6198_RS19820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS6198_RS19825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS6198_RS19830	COG2207	Transcriptional regulator
MS6198_RS19840	COG0076	glutamate decarboxylase activity
MS6198_RS19845	COG1858	cytochrome C peroxidase
MS6198_RS19855	COG2197	response regulator
MS6198_RS19860	COG0583	DNA-binding transcription factor activity
MS6198_RS19865	COG1295	ribonuclease BN
MS6198_RS19870	COG0477	Major facilitator Superfamily
MS6198_RS19875	COG2982	Protein involved in outer membrane biogenesis
MS6198_RS19880	COG2200	EAL domain
MS6198_RS19890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS19895	COG0612	Peptidase, M16
MS6198_RS19905	COG2199	diguanylate cyclase activity
MS6198_RS19905	COG2200	EAL domain
MS6198_RS19910	COG3118	belongs to the thioredoxin family
MS6198_RS19910	COG0457	Tetratricopeptide repeat
MS6198_RS19915	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MS6198_RS19920	COG1215	transferase activity, transferring glycosyl groups
MS6198_RS19925	COG1215	transferase activity, transferring glycosyl groups
MS6198_RS19950	COG2194	sulfuric ester hydrolase activity
MS6198_RS19975	COG0814	amino acid
MS6198_RS19980	COG4608	Belongs to the ABC transporter superfamily
MS6198_RS19985	COG0444	Belongs to the ABC transporter superfamily
MS6198_RS19990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS6198_RS19995	COG0601	transmembrane transport
MS6198_RS20005	COG0747	negative chemotaxis
MS6198_RS20015	COG2801	Transposase and inactivated derivatives
MS6198_RS20030	COG2194	sulfuric ester hydrolase activity
MS6198_RS20035	COG2223	nitrite transmembrane transporter activity
MS6198_RS20040	COG5571	outer membrane autotransporter
MS6198_RS20045	COG2818	Glycosylase
MS6198_RS20050	COG0456	acetyltransferase
MS6198_RS20055	COG0243	molybdopterin cofactor binding
MS6198_RS20060	COG2885	chlorophyll binding
MS6198_RS20075	COG2944	sequence-specific DNA binding
MS6198_RS20080	COG1278	Cold shock
MS6198_RS20090	COG2801	Transposase and inactivated derivatives
MS6198_RS20095	COG2963	transposase activity
MS6198_RS20115	COG3274	enterobacterial common antigen metabolic process
MS6198_RS20120	COG4682	membrane
MS6198_RS20125	COG4682	membrane
MS6198_RS20130	COG1070	Carbohydrate kinase
MS6198_RS20140	COG4213	ABC transporter substrate-binding protein
MS6198_RS20150	COG4214	carbohydrate transport
MS6198_RS20155	COG2207	Transcriptional regulator
MS6198_RS20155	COG1609	Transcriptional regulator
MS6198_RS20160	COG2992	FlgJ-related protein
MS6198_RS20165	COG0366	Alpha amylase catalytic
MS6198_RS20170	COG3977	Valine--pyruvate aminotransferase
MS6198_RS20175	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS6198_RS20180	COG1414	Transcriptional regulator
MS6198_RS20190	COG2731	YhcH YjgK YiaL family protein
MS6198_RS20195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MS6198_RS20200	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MS6198_RS20205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MS6198_RS20210	COG1070	Carbohydrate kinase
MS6198_RS20215	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MS6198_RS20220	COG3623	hexulose-6-phosphate isomerase
MS6198_RS20225	COG0235	Class ii aldolase
MS6198_RS20235	COG2211	Major facilitator Superfamily
MS6198_RS20265	COG1012	belongs to the aldehyde dehydrogenase family
MS6198_RS20275	COG1454	alcohol dehydrogenase
MS6198_RS20280	COG3276	selenocysteine insertion sequence binding
MS6198_RS20290	COG0625	glutathione transferase activity
MS6198_RS20295	COG3209	COG3209 Rhs family protein
MS6198_RS20305	COG1413	lyase activity
MS6198_RS20310	COG3209	COG3209 Rhs family protein
MS6198_RS20320	COG5433	transposase activity
MS6198_RS20335	COG1566	PFAM secretion protein HlyD family protein
MS6198_RS20345	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS20345	COG2213	PTS system mannitol-specific
MS6198_RS20355	COG3722	fumarate hydratase activity
MS6198_RS20375	COG5295	Hep Hag repeat protein
MS6198_RS20380	COG1620	l-lactate permease
MS6198_RS20385	COG2186	Transcriptional regulator
MS6198_RS20395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MS6198_RS20400	COG1045	serine acetyltransferase
MS6198_RS20415	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MS6198_RS20420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MS6198_RS20430	COG4942	peptidase
MS6198_RS20435	COG2861	carbohydrate metabolic process
MS6198_RS20440	COG1216	Glycosyl transferase, family 2
MS6198_RS20450	COG0156	8-amino-7-oxononanoate synthase activity
MS6198_RS20460	COG0859	PFAM glycosyl transferase family 9
MS6198_RS20465	COG0859	PFAM glycosyl transferase family 9
MS6198_RS20480	COG1442	glycosyl transferase family 8
MS6198_RS20485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MS6198_RS20500	COG0515	serine threonine protein kinase
MS6198_RS20505	COG0438	transferase activity, transferring glycosyl groups
MS6198_RS20510	COG0859	PFAM glycosyl transferase family 9
MS6198_RS20515	COG1519	Transferase
MS6198_RS20545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MS6198_RS20575	COG1561	YicC-like family, N-terminal region
MS6198_RS20580	COG3645	SOS response
MS6198_RS20585	COG2860	membrane
MS6198_RS20590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MS6198_RS20595	COG0194	GDP metabolic process
MS6198_RS20605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MS6198_RS20610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MS6198_RS20615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MS6198_RS20620	COG0786	glutamate:sodium symporter activity
MS6198_RS20625	COG2233	PERMEase
MS6198_RS20630	COG2982	Protein involved in outer membrane biogenesis
MS6198_RS20640	COG1940	carbohydrate kinase activity
MS6198_RS20655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS20655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS20660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS20665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS20665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS20665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS20670	COG3711	transcriptional antiterminator
MS6198_RS20675	COG1501	Belongs to the glycosyl hydrolase 31 family
MS6198_RS20680	COG2211	Major facilitator Superfamily
MS6198_RS20695	COG2814	Major facilitator Superfamily
MS6198_RS20700	COG0697	spore germination
MS6198_RS20705	COG1464	Belongs to the NlpA lipoprotein family
MS6198_RS20720	COG0457	Tetratricopeptide repeat
MS6198_RS20745	COG2373	Large extracellular alpha-helical protein
MS6198_RS20745	COG4932	domain protein
MS6198_RS20745	COG1388	LysM domain
MS6198_RS20775	COG2252	PERMEase
MS6198_RS20785	COG2271	Major facilitator Superfamily
MS6198_RS20790	COG2271	Major facilitator Superfamily
MS6198_RS20795	COG3851	Histidine kinase
MS6198_RS20800	COG2197	response regulator
MS6198_RS20815	COG0440	acetolactate synthase activity
MS6198_RS20820	COG0028	Belongs to the TPP enzyme family
MS6198_RS20845	COG2814	Major facilitator Superfamily
MS6198_RS20850	COG0641	radical SAM
MS6198_RS20860	COG2149	membrane
MS6198_RS20865	COG3119	arylsulfatase activity
MS6198_RS20870	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MS6198_RS20875	COG2207	Transcriptional regulator
MS6198_RS20890	COG2188	Transcriptional regulator
MS6198_RS20910	COG5645	(Lipo)protein
MS6198_RS20915	COG0823	Involved in the tonB-independent uptake of proteins
MS6198_RS20925	COG2271	Major facilitator Superfamily
MS6198_RS20935	COG0800	Aldolase
MS6198_RS20940	COG3734	2-keto-3-deoxy-galactonokinase
MS6198_RS20945	COG2186	Transcriptional regulator
MS6198_RS20955	COG0561	phosphatase activity
MS6198_RS20960	COG3753	Protein conserved in bacteria
MS6198_RS20970	COG0187	DNA topoisomerase II activity
MS6198_RS20980	COG0592	DNA-directed DNA polymerase activity
MS6198_RS21025	COG0814	amino acid
MS6198_RS21035	COG0583	DNA-binding transcription factor activity
MS6198_RS21040	COG2091	lysine biosynthetic process via aminoadipic acid
MS6198_RS21045	COG0431	NADPH-dependent FMN reductase
MS6198_RS21050	COG2252	PERMEase
MS6198_RS21055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS6198_RS21090	COG0704	Plays a role in the regulation of phosphate uptake
MS6198_RS21095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MS6198_RS21100	COG0581	inorganic phosphate transmembrane transporter activity
MS6198_RS21105	COG0573	inorganic phosphate transmembrane transporter activity
MS6198_RS21110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MS6198_RS21185	COG3312	ion transport
MS6198_RS21200	COG0716	FMN binding
MS6198_RS21205	COG1522	sequence-specific DNA binding
MS6198_RS21235	COG1129	ABC transporter
MS6198_RS21240	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS6198_RS21245	COG1879	ABC-type sugar transport system periplasmic component
MS6198_RS21250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS21255	COG1609	Transcriptional regulator
MS6198_RS21260	COG0477	Major facilitator Superfamily
MS6198_RS21265	COG2186	Transcriptional regulator
MS6198_RS21305	COG3085	chromosome segregation
MS6198_RS21325	COG3978	acetolactate synthase activity
MS6198_RS21330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MS6198_RS21340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MS6198_RS21345	COG0583	DNA-binding transcription factor activity
MS6198_RS21355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MS6198_RS21360	COG0210	DNA helicase
MS6198_RS21375	COG3118	belongs to the thioredoxin family
MS6198_RS21385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MS6198_RS21395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MS6198_RS21400	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
MS6198_RS21405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MS6198_RS21410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MS6198_RS21415	COG1088	dTDP-glucose 4,6-dehydratase activity
MS6198_RS21420	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MS6198_RS21425	COG0456	acetyltransferase
MS6198_RS21430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MS6198_RS21435	COG2244	polysaccharide biosynthetic process
MS6198_RS21455	COG1113	amino acid transport
MS6198_RS21480	COG0641	radical SAM
MS6198_RS21485	COG3119	arylsulfatase activity
MS6198_RS21495	COG3071	HemY protein
MS6198_RS21500	COG2959	enzyme of heme biosynthesis
MS6198_RS21505	COG1587	Uroporphyrinogen-III synthase
MS6198_RS21515	COG3072	Adenylate cyclase
MS6198_RS21525	COG5567	small periplasmic lipoprotein
MS6198_RS21535	COG3159	Protein conserved in bacteria
MS6198_RS21545	COG1011	Hydrolase
MS6198_RS21550	COG0210	DNA helicase
MS6198_RS21555	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
MS6198_RS21560	COG3698	Phosphodiester glycosidase
MS6198_RS21570	COG0598	Magnesium transport protein CorA
MS6198_RS21600	COG2962	Rard protein
MS6198_RS21605	COG2050	protein possibly involved in aromatic compounds catabolism
MS6198_RS21610	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
MS6198_RS21615	COG0514	ATP-dependent DNA helicase (RecQ)
MS6198_RS21620	COG1280	lysine exporter protein (LysE YggA)
MS6198_RS21630	COG1280	lysine exporter protein (LysE YggA)
MS6198_RS21635	COG2267	carboxylic ester hydrolase activity
MS6198_RS21640	COG0561	phosphatase activity
MS6198_RS21645	COG0697	spore germination
MS6198_RS21650	COG0583	DNA-binding transcription factor activity
MS6198_RS21660	COG0583	DNA-binding transcription factor activity
MS6198_RS21665	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MS6198_RS21675	COG0549	Belongs to the carbamate kinase family
MS6198_RS21680	COG1304	FMN binding
MS6198_RS21685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MS6198_RS21695	COG1335	isochorismatase
MS6198_RS21705	COG0412	Dienelactone hydrolase
MS6198_RS21710	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MS6198_RS21730	COG0800	Aldolase
MS6198_RS21735	COG3734	2-keto-3-deoxy-galactonokinase
MS6198_RS21740	COG1414	Transcriptional regulator
MS6198_RS21745	COG1322	Protein conserved in bacteria
MS6198_RS21755	COG3165	ubiquinone biosynthetic process from chorismate
MS6198_RS21765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MS6198_RS21770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MS6198_RS21775	COG0805	protein transport
MS6198_RS21785	COG0250	Participates in transcription elongation, termination and antitermination
MS6198_RS21790	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MS6198_RS21795	COG0543	2 iron, 2 sulfur cluster binding
MS6198_RS21815	COG1739	Uncharacterized protein family UPF0029
MS6198_RS21820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MS6198_RS21825	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
MS6198_RS21855	COG1763	Mo-molybdopterin cofactor biosynthetic process
MS6198_RS21860	COG0746	molybdenum cofactor guanylyltransferase activity
MS6198_RS21865	COG3084	Protein conserved in bacteria
MS6198_RS21870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MS6198_RS21875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MS6198_RS21880	COG5339	Protein conserved in bacteria
MS6198_RS21885	COG0204	Acyl-transferase
MS6198_RS21895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MS6198_RS21895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MS6198_RS21910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MS6198_RS21920	COG2204	response regulator
MS6198_RS21925	COG3852	Histidine kinase
MS6198_RS21930	COG0174	glutamine synthetase
MS6198_RS21940	COG1217	gtp-binding protein TYPA
MS6198_RS21945	COG0561	phosphatase activity
MS6198_RS21955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MS6198_RS21975	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MS6198_RS21980	COG2211	Major facilitator Superfamily
MS6198_RS21985	COG2211	Major facilitator Superfamily
MS6198_RS21990	COG1501	Belongs to the glycosyl hydrolase 31 family
MS6198_RS22000	COG2017	converts alpha-aldose to the beta-anomer
MS6198_RS22005	COG2942	2-epimerase
MS6198_RS22010	COG3684	Belongs to the aldolase LacD family
MS6198_RS22015	COG2084	Dehydrogenase
MS6198_RS22020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS6198_RS22025	COG1349	DNA-binding transcription factor activity
MS6198_RS22030	COG1011	Hydrolase
MS6198_RS22045	COG0456	acetyltransferase
MS6198_RS22055	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
MS6198_RS22080	COG2864	formate dehydrogenase
MS6198_RS22085	COG0437	4 iron, 4 sulfur cluster binding
MS6198_RS22090	COG0243	molybdopterin cofactor binding
MS6198_RS22090	COG3383	formate dehydrogenase (NAD+) activity
MS6198_RS22095	COG0243	molybdopterin cofactor binding
MS6198_RS22095	COG3383	formate dehydrogenase (NAD+) activity
MS6198_RS22110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS22110	COG3711	transcriptional antiterminator
MS6198_RS22115	COG1363	Peptidase, m42
MS6198_RS22120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS22120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS22125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS22175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MS6198_RS22190	COG2258	MOSC domain
MS6198_RS22195	COG2205	protein histidine kinase activity
MS6198_RS22200	COG0745	RESPONSE REGULATOR receiver
MS6198_RS22205	COG3678	ATP-independent chaperone mediated protein folding
MS6198_RS22220	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MS6198_RS22240	COG3152	Membrane
MS6198_RS22245	COG3691	Protein conserved in bacteria
MS6198_RS22250	COG0589	response to stress
MS6198_RS22260	COG1494	fructose-1,6-bisphosphatase
MS6198_RS22270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MS6198_RS22285	COG1575	Belongs to the MenA family. Type 1 subfamily
MS6198_RS22300	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MS6198_RS22305	COG1609	Transcriptional regulator
MS6198_RS22310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MS6198_RS22320	COG3209	COG3209 Rhs family protein
MS6198_RS22330	COG3209	COG3209 Rhs family protein
MS6198_RS22360	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MS6198_RS22370	COG0626	cystathionine gamma-synthase activity
MS6198_RS22375	COG0527	aspartate kinase activity
MS6198_RS22375	COG0460	homoserine dehydrogenase
MS6198_RS22385	COG0737	Belongs to the 5'-nucleotidase family
MS6198_RS22390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MS6198_RS22400	COG0697	spore germination
MS6198_RS22405	COG3738	Protein conserved in bacteria
MS6198_RS22410	COG0371	Dehydrogenase
MS6198_RS22415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MS6198_RS22420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MS6198_RS22420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS22420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS22425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS22430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS22435	COG1882	Formate acetyltransferase
MS6198_RS22440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MS6198_RS22445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS6198_RS22450	COG2207	Transcriptional regulator
MS6198_RS22455	COG2194	sulfuric ester hydrolase activity
MS6198_RS22470	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MS6198_RS22485	COG4948	Mandelate Racemase Muconate Lactonizing
MS6198_RS22490	COG2271	Major facilitator Superfamily
MS6198_RS22495	COG0583	DNA-binding transcription factor activity
MS6198_RS22520	COG4206	TonB-dependent receptor
MS6198_RS22555	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MS6198_RS22555	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MS6198_RS22595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MS6198_RS22600	COG0250	Participates in transcription elongation, termination and antitermination
MS6198_RS22635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MS6198_RS22645	COG2104	thiamine diphosphate biosynthetic process
MS6198_RS22650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MS6198_RS22685	COG3068	Protein conserved in bacteria
MS6198_RS22700	COG3678	ATP-independent chaperone mediated protein folding
MS6198_RS22705	COG4191	Histidine kinase
MS6198_RS22710	COG2204	response regulator
MS6198_RS22715	COG0151	Belongs to the GarS family
MS6198_RS22755	COG0456	acetyltransferase
MS6198_RS22765	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MS6198_RS22770	COG2224	Isocitrate lyase
MS6198_RS22780	COG1414	Transcriptional regulator
MS6198_RS22785	COG1410	methionine synthase
MS6198_RS22785	COG0646	methionine synthase
MS6198_RS22790	COG1283	sodium-dependent phosphate transmembrane transporter activity
MS6198_RS22800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MS6198_RS22840	COG1187	pseudouridine synthase activity
MS6198_RS22855	COG3541	Predicted nucleotidyltransferase
MS6198_RS22870	COG5301	cellulose 1,4-beta-cellobiosidase activity
MS6198_RS22945	COG0741	lytic transglycosylase activity
MS6198_RS22960	COG0527	aspartate kinase activity
MS6198_RS22985	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS6198_RS23005	COG3833	ABC-type maltose transport systems, permease component
MS6198_RS23010	COG1175	transmembrane transport
MS6198_RS23015	COG2182	Extracellular solute-binding protein
MS6198_RS23025	COG3842	ATPase activity
MS6198_RS23040	COG1357	PFAM Pentapeptide repeats (8 copies)
MS6198_RS23060	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MS6198_RS23070	COG0534	Mate efflux family protein
MS6198_RS23075	COG3237	CsbD-like
MS6198_RS23080	COG0735	belongs to the Fur family
MS6198_RS23120	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MS6198_RS23125	COG5532	Uncharacterized conserved protein (DUF2303)
MS6198_RS23160	COG1846	Transcriptional regulator
MS6198_RS23165	COG4725	Belongs to the MT-A70-like family
MS6198_RS23175	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MS6198_RS23185	COG1403	HNH endonuclease
MS6198_RS23190	COG0484	heat shock protein binding
MS6198_RS23220	COG3772	lysozyme
MS6198_RS23260	COG0740	serine-type endopeptidase activity
MS6198_RS23335	COG5301	cellulose 1,4-beta-cellobiosidase activity
MS6198_RS23365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MS6198_RS23375	COG0604	alcohol dehydrogenase
MS6198_RS23380	COG0305	Participates in initiation and elongation during chromosome replication
MS6198_RS23385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MS6198_RS23390	COG1448	Aminotransferase
MS6198_RS23400	COG3700	Belongs to the class B bacterial acid phosphatase family
MS6198_RS23405	COG0432	Pfam Uncharacterised protein family UPF0047
MS6198_RS23410	COG2315	Protein conserved in bacteria
MS6198_RS23415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MS6198_RS23420	COG0629	single-stranded DNA binding
MS6198_RS23430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MS6198_RS23435	COG2207	Transcriptional regulator
MS6198_RS23440	COG0789	Transcriptional regulator
MS6198_RS23445	COG2252	PERMEase
MS6198_RS23450	COG0025	NhaP-type Na H and K H
MS6198_RS23460	COG3162	membrane
MS6198_RS23465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MS6198_RS23475	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
MS6198_RS23480	COG0437	4 iron, 4 sulfur cluster binding
MS6198_RS23485	COG3301	Polysulphide reductase, NrfD
MS6198_RS23490	COG1138	Cytochrome C-type biogenesis protein
MS6198_RS23495	COG3088	subunit of a heme lyase
MS6198_RS23500	COG4235	cytochrome complex assembly
MS6198_RS23505	COG1301	dicarboxylic acid transport
MS6198_RS23510	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MS6198_RS23515	COG3383	formate dehydrogenase (NAD+) activity
MS6198_RS23520	COG3383	formate dehydrogenase (NAD+) activity
MS6198_RS23530	COG1289	transmembrane transporter activity
MS6198_RS23535	COG1566	PFAM secretion protein HlyD family protein
MS6198_RS23545	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MS6198_RS23550	COG1940	carbohydrate kinase activity
MS6198_RS23555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MS6198_RS23560	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS6198_RS23565	COG1129	ABC transporter
MS6198_RS23570	COG1879	ABC-type sugar transport system periplasmic component
MS6198_RS23575	COG1737	Transcriptional regulator
MS6198_RS23580	COG0698	ribose 5-phosphate isomerase
MS6198_RS23590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MS6198_RS23595	COG0456	acetyltransferase
MS6198_RS23605	COG3454	Phosphonate metabolism
MS6198_RS23610	COG4778	phosphonate C-P lyase system protein PhnL
MS6198_RS23615	COG4107	phosphonate C-P lyase system protein PhnK
MS6198_RS23620	COG3627	carbon phosphorus lyase activity
MS6198_RS23625	COG3626	phosphonate metabolism
MS6198_RS23630	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
MS6198_RS23635	COG3624	Phosphonate C-P lyase system protein PhnG
MS6198_RS23640	COG2188	Transcriptional regulator
MS6198_RS23645	COG3639	organic phosphonate transmembrane transporter activity
MS6198_RS23650	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MS6198_RS23660	COG2764	glyoxalase bleomycin resistance protein dioxygenase
MS6198_RS23665	COG2824	Alkylphosphonate utilization operon protein PhnA
MS6198_RS23670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MS6198_RS23680	COG0477	Major facilitator Superfamily
MS6198_RS23690	COG0642	Histidine kinase
MS6198_RS23695	COG0745	RESPONSE REGULATOR receiver
MS6198_RS23700	COG2194	sulfuric ester hydrolase activity
MS6198_RS23705	COG0531	amino acid
MS6198_RS23710	COG2207	Transcriptional regulator
MS6198_RS23715	COG1982	Orn Lys Arg decarboxylase major
MS6198_RS23720	COG2169	Transcriptional regulator
MS6198_RS23730	COG1486	melibiose metabolic process
MS6198_RS23735	COG3647	Membrane
MS6198_RS23740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MS6198_RS23740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MS6198_RS23745	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MS6198_RS23755	COG4565	transcriptional regulatory protein
MS6198_RS23760	COG3290	protein histidine kinase activity
MS6198_RS23765	COG3592	Divergent 4Fe-4S mono-cluster
MS6198_RS23770	COG2388	GCN5-related N-acetyl-transferase
MS6198_RS23785	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MS6198_RS23790	COG3104	oligopeptide transport
MS6198_RS23795	COG1982	Orn Lys Arg decarboxylase major
MS6198_RS23800	COG0531	amino acid
MS6198_RS23805	COG3710	Transcriptional regulator
MS6198_RS23820	COG1309	transcriptional regulator
MS6198_RS23835	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MS6198_RS23840	COG1027	Aspartate ammonia-lyase
MS6198_RS23845	COG3030	protein affecting phage T7 exclusion by the F plasmid
MS6198_RS23850	COG0531	amino acid
MS6198_RS23875	COG1509	lysine 2,3-aminomutase activity
MS6198_RS23885	COG5510	response to toxic substance
MS6198_RS23890	COG5510	response to toxic substance
MS6198_RS23895	COG2076	Multidrug Resistance protein
MS6198_RS23900	COG3040	lipid binding
MS6198_RS23905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MS6198_RS23920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MS6198_RS23925	COG1053	succinate dehydrogenase
MS6198_RS23935	COG0531	amino acid
MS6198_RS23940	COG3264	Mechanosensitive ion channel
MS6198_RS23940	COG1511	domain protein
MS6198_RS23980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MS6198_RS23980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MS6198_RS23985	COG0802	atpase or kinase
MS6198_RS23990	COG0860	N-Acetylmuramoyl-L-alanine amidase
MS6198_RS24010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MS6198_RS24015	COG0330	HflC and HflK could
MS6198_RS24020	COG0330	HflC and HflK could
MS6198_RS24025	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
MS6198_RS24040	COG0557	exoribonuclease II activity
MS6198_RS24045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MS6198_RS24050	COG3789	protein conserved in bacteria
MS6198_RS24055	COG1842	Phage shock protein A
MS6198_RS24065	COG3766	membrane
MS6198_RS24070	COG5463	Belongs to the UPF0441 family
MS6198_RS24075	COG0754	glutathionylspermidine amidase activity
MS6198_RS24080	COG1960	acyl-CoA dehydrogenase activity
MS6198_RS24090	COG3650	response to hydrogen peroxide
MS6198_RS24095	COG1073	alpha beta
MS6198_RS24110	COG3037	sugar-specific permease SgaT UlaA
MS6198_RS24115	COG3414	Phosphotransferase system galactitol-specific IIB component
MS6198_RS24155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MS6198_RS24170	COG2271	Major facilitator Superfamily
MS6198_RS24175	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MS6198_RS24180	COG4670	ketone body catabolic process
MS6198_RS24185	COG1024	Enoyl-CoA hydratase
MS6198_RS24200	COG1309	transcriptional regulator
MS6198_RS24205	COG3061	Opacity-associated protein A
MS6198_RS24210	COG0545	Peptidyl-prolyl cis-trans isomerase
MS6198_RS24215	COG1113	amino acid transport
MS6198_RS24225	COG0697	spore germination
MS6198_RS24230	COG0702	epimerase
MS6198_RS24235	COG1733	regulation of RNA biosynthetic process
MS6198_RS24240	COG0737	Belongs to the 5'-nucleotidase family
MS6198_RS24245	COG1218	3'(2'),5'-bisphosphate nucleotidase
MS6198_RS24250	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
MS6198_RS24260	COG1253	flavin adenine dinucleotide binding
MS6198_RS24275	COG0729	surface antigen
MS6198_RS24280	COG2911	Protein conserved in bacteria
MS6198_RS24285	COG2105	PFAM AIG2 family protein
MS6198_RS24290	COG2336	PFAM SpoVT AbrB
MS6198_RS24295	COG2337	Toxic component of a toxin-antitoxin (TA) module
MS6198_RS24300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MS6198_RS24305	COG1879	ABC-type sugar transport system periplasmic component
MS6198_RS24310	COG1129	ABC transporter
MS6198_RS24315	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS6198_RS24320	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS6198_RS24330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MS6198_RS24340	COG0312	modulator of DNA gyrase
MS6198_RS24345	COG3783	Cytochrome b(562)
MS6198_RS24350	COG0602	queuosine metabolic process
MS6198_RS24355	COG1328	CTP reductase activity
MS6198_RS24360	COG0366	Alpha amylase catalytic
MS6198_RS24365	COG1263	PTS System
MS6198_RS24365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS6198_RS24370	COG1609	Transcriptional regulator
MS6198_RS24375	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MS6198_RS24380	COG0251	oxidation-reduction process
MS6198_RS24405	COG0251	oxidation-reduction process
MS6198_RS24410	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS24415	COG1309	transcriptional regulator
MS6198_RS24420	COG2731	YhcH YjgK YiaL family protein
MS6198_RS24445	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
MS6198_RS24450	COG0456	acetyltransferase
MS6198_RS24455	COG4269	membrane
MS6198_RS24460	COG0525	valine-tRNA ligase activity
MS6198_RS24465	COG2927	DNA polymerase III (CHI subunit)
MS6198_RS24475	COG0795	lipopolysaccharide-transporting ATPase activity
MS6198_RS24480	COG0795	lipopolysaccharide-transporting ATPase activity
MS6198_RS24485	COG0433	COG0433 Predicted ATPase
MS6198_RS24490	COG1609	Transcriptional regulator
MS6198_RS24495	COG2610	gluconate transmembrane transporter activity
MS6198_RS24500	COG1028	Short-chain dehydrogenase reductase Sdr
MS6198_RS24505	COG1063	alcohol dehydrogenase
MS6198_RS24510	COG3265	gluconokinase activity
MS6198_RS24515	COG1064	alcohol dehydrogenase
MS6198_RS24525	COG0582	viral genome integration into host DNA
MS6198_RS24550	COG3385	transposase activity
MS6198_RS24555	COG2814	Major facilitator Superfamily
MS6198_RS24560	COG0673	inositol 2-dehydrogenase activity
MS6198_RS24590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS6198_RS24600	COG2826	transposase and inactivated derivatives, IS30 family
MS6198_RS24615	COG2085	NADP oxidoreductase coenzyme F420-dependent
MS6198_RS24620	COG1120	ATPase activity
MS6198_RS24625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS6198_RS24630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS6198_RS24635	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MS6198_RS24640	COG4772	TonB-dependent receptor
MS6198_RS24645	COG3712	iron ion homeostasis
MS6198_RS24650	COG1595	DNA-templated transcription, initiation
MS6198_RS24655	COG3677	Transposase
MS6198_RS24690	COG4372	Transposase
MS6198_RS24695	COG3436	PFAM IS66 Orf2 family protein
MS6198_RS24740	COG4983	Phage plasmid primase, P4 family domain protein
MS6198_RS24755	COG3468	outer membrane autotransporter barrel domain protein
MS6198_RS24780	COG2003	Belongs to the UPF0758 family
MS6198_RS24820	COG2390	Transcriptional regulator
MS6198_RS24830	COG2610	gluconate transmembrane transporter activity
MS6198_RS24835	COG0129	dihydroxy-acid dehydratase activity
MS6198_RS24840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MS6198_RS24845	COG1414	Transcriptional regulator
MS6198_RS24850	COG1349	DNA-binding transcription factor activity
MS6198_RS24855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MS6198_RS24860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS6198_RS24865	COG0434	BtpA family
MS6198_RS24870	COG3775	system Galactitol-specific IIC component
MS6198_RS24875	COG3414	Phosphotransferase system galactitol-specific IIB component
MS6198_RS24880	COG1363	Peptidase, m42
MS6198_RS24885	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MS6198_RS24890	COG3153	acetyltransferase
MS6198_RS24910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MS6198_RS24910	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MS6198_RS24915	COG3039	Transposase
MS6198_RS24925	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MS6198_RS24930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MS6198_RS24945	COG0582	viral genome integration into host DNA
MS6198_RS24950	COG4974	Belongs to the 'phage' integrase family
MS6198_RS24960	COG3539	Fimbrial protein
MS6198_RS24965	COG3539	Fimbrial protein
MS6198_RS24970	COG3121	Chaperone
MS6198_RS24975	COG3188	usher protein
MS6198_RS24980	COG3539	Fimbrial protein
MS6198_RS24985	COG3539	Fimbrial protein
MS6198_RS24990	COG3539	Fimbrial protein
MS6198_RS24995	COG2610	gluconate transmembrane transporter activity
MS6198_RS25010	COG0246	Mannitol dehydrogenase
MS6198_RS25020	COG2186	Transcriptional regulator
MS6198_RS25045	COG0583	DNA-binding transcription factor activity
MS6198_RS25050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MS6198_RS25055	COG0700	Nucleoside recognition
MS6198_RS25060	COG3366	ferrous iron transmembrane transporter activity
MS6198_RS25070	COG0477	Major facilitator Superfamily
MS6198_RS25075	COG3204	pilus organization
MS6198_RS25085	COG1924	4 iron, 4 sulfur cluster binding
MS6198_RS25090	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
MS6198_RS25095	COG2733	membrane
MS6198_RS25100	COG2814	Major facilitator Superfamily
MS6198_RS25110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS6198_RS25115	COG5457	Domain of unknown function (DUF1127)
MS6198_RS25120	COG1196	nuclear chromosome segregation
MS6198_RS25130	COG4268	DNA restriction-modification system
MS6198_RS25135	COG1401	restriction endodeoxyribonuclease activity
MS6198_RS25145	COG0732	type I restriction modification DNA specificity domain
MS6198_RS25150	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MS6198_RS25155	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MS6198_RS25160	COG1715	Restriction endonuclease
MS6198_RS25165	COG0523	cobalamin synthesis protein
MS6198_RS25170	COG2879	small protein
MS6198_RS25175	COG1966	Carbon starvation protein
MS6198_RS25185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS6198_RS25190	COG2368	4-hydroxyphenylacetate
MS6198_RS25210	COG3971	2-oxopent-4-enoate hydratase activity
MS6198_RS25220	COG3384	dioxygenase
MS6198_RS25225	COG1012	belongs to the aldehyde dehydrogenase family
MS6198_RS25230	COG0179	Fumarylacetoacetate (FAA) hydrolase
MS6198_RS25235	COG1846	Transcriptional regulator
MS6198_RS25240	COG0840	transmembrane signaling receptor activity
MS6198_RS25245	COG2271	Major facilitator Superfamily
MS6198_RS25250	COG1802	Transcriptional regulator
MS6198_RS25255	COG1063	alcohol dehydrogenase
MS6198_RS25270	COG1484	DNA-dependent DNA replication
MS6198_RS25285	COG2966	Psort location CytoplasmicMembrane, score
MS6198_RS25290	COG2197	response regulator
MS6198_RS25295	COG2197	response regulator
MS6198_RS25300	COG4114	ferric iron reductase
MS6198_RS25335	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
MS6198_RS25340	COG0456	acetyltransferase
MS6198_RS25345	COG1011	Hydrolase
MS6198_RS25355	COG2823	Periplasmic or secreted lipoprotein
MS6198_RS25365	COG4667	esterase of the alpha-beta hydrolase superfamily
MS6198_RS25370	COG0084	hydrolase, TatD family'
MS6198_RS25375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MS6198_RS25380	COG1328	CTP reductase activity
MS6198_RS25420	COG3726	membrane protein affecting hemolysin expression
MS6198_RS25425	COG0560	Phosphoserine phosphatase
MS6198_RS25430	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MS6198_RS25435	COG3172	ATPase kinase involved in NAD metabolism
MS6198_RS25435	COG1056	cytidyltransferase-related domain
MS6198_RS25440	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
MS6198_RS25450	COG0488	(ABC) transporter
MS6198_RS25455	COG0741	lytic transglycosylase activity
MS6198_RS25475	COG2207	Transcriptional regulator
MS6198_RS25475	COG3708	Transcriptional regulator
MS6198_RS25480	COG3045	CreA protein
MS6198_RS25485	COG0745	RESPONSE REGULATOR receiver
MS6198_RS25490	COG2205	protein histidine kinase activity
MS6198_RS25495	COG4452	Inner membrane protein CreD
MS6198_RS25500	COG0745	RESPONSE REGULATOR receiver
MS6198_RS25510	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MS6198_RS25540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MS6198_RS25925	COG2271	Major facilitator Superfamily
MS6198_RS25930	COG2271	Major facilitator Superfamily
MS6198_RS26155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MS6198_RS26190	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MS6198_RS26330	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MS6198_RS26625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MS6198_RS26810	COG0417	DNA replication proofreading
MS6198_RS26865	COG0586	Pfam SNARE associated Golgi protein
MS6198_RS26915	COG0473	3-isopropylmalate dehydrogenase activity
MS6198_RS27215	COG1115	amino acid carrier protein
MS6198_RS27295	COG3188	usher protein
MS6198_RS27500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MS6198_RS27515	COG2271	Major facilitator Superfamily
MS6198_RS27745	COG0460	homoserine dehydrogenase
MS6198_RS27745	COG0527	aspartate kinase activity
MS6198_RS27825	COG1584	GPR1 FUN34 yaaH family protein
MS6198_RS27895	COG3188	usher protein
MS6198_RS27900	COG3188	usher protein