locus-tag	class	description
FK543_RS00095	COG1475	DNA binding
FK543_RS00235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK543_RS00240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK543_RS00245	COG1121	(ABC) transporter
FK543_RS00315	COG4571	Outer membrane protease
FK543_RS00420	COG2382	esterase
FK543_RS00425	COG2819	hydrolase of the alpha beta superfamily
FK543_RS00630	COG1695	Transcriptional regulator
FK543_RS00665	COG3173	Aminoglycoside phosphotransferase
FK543_RS00690	COG5001	Diguanylate cyclase
FK543_RS00690	COG3300	MHYT domain
FK543_RS00775	COG4644	lycopene metabolic process
FK543_RS00820	COG1196	nuclear chromosome segregation
FK543_RS00830	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FK543_RS00845	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FK543_RS00985	COG0592	DNA-directed DNA polymerase activity
FK543_RS00995	COG0187	DNA topoisomerase II activity
FK543_RS01000	COG3753	Protein conserved in bacteria
FK543_RS01005	COG0561	phosphatase activity
FK543_RS01015	COG2186	Transcriptional regulator
FK543_RS01020	COG3734	2-keto-3-deoxy-galactonokinase
FK543_RS01025	COG0800	Aldolase
FK543_RS01035	COG2271	Major facilitator Superfamily
FK543_RS01045	COG0823	Involved in the tonB-independent uptake of proteins
FK543_RS01050	COG5645	(Lipo)protein
FK543_RS01070	COG2188	Transcriptional regulator
FK543_RS01085	COG2207	Transcriptional regulator
FK543_RS01090	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FK543_RS01095	COG3119	arylsulfatase activity
FK543_RS01105	COG2149	membrane
FK543_RS01115	COG0641	radical SAM
FK543_RS01120	COG2814	Major facilitator Superfamily
FK543_RS01135	COG0028	Belongs to the TPP enzyme family
FK543_RS01140	COG0440	acetolactate synthase activity
FK543_RS01145	COG2197	response regulator
FK543_RS01150	COG3851	Histidine kinase
FK543_RS01155	COG2271	Major facilitator Superfamily
FK543_RS01160	COG2271	Major facilitator Superfamily
FK543_RS01170	COG2252	PERMEase
FK543_RS01190	COG1464	Belongs to the NlpA lipoprotein family
FK543_RS01195	COG0697	spore germination
FK543_RS01200	COG2814	Major facilitator Superfamily
FK543_RS01215	COG2211	Major facilitator Superfamily
FK543_RS01220	COG1501	Belongs to the glycosyl hydrolase 31 family
FK543_RS01225	COG2982	Protein involved in outer membrane biogenesis
FK543_RS01230	COG2233	PERMEase
FK543_RS01235	COG0786	glutamate:sodium symporter activity
FK543_RS01245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FK543_RS01250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FK543_RS01255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FK543_RS01265	COG0194	GDP metabolic process
FK543_RS01275	COG2860	membrane
FK543_RS01280	COG3645	SOS response
FK543_RS01285	COG1561	YicC-like family, N-terminal region
FK543_RS01310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FK543_RS01340	COG1519	Transferase
FK543_RS01345	COG0859	PFAM glycosyl transferase family 9
FK543_RS01350	COG0438	transferase activity, transferring glycosyl groups
FK543_RS01355	COG0515	serine threonine protein kinase
FK543_RS01365	COG3642	lipopolysaccharide core region biosynthetic process
FK543_RS01385	COG0859	PFAM glycosyl transferase family 9
FK543_RS01390	COG0859	PFAM glycosyl transferase family 9
FK543_RS01405	COG0156	8-amino-7-oxononanoate synthase activity
FK543_RS01415	COG1216	Glycosyl transferase, family 2
FK543_RS01420	COG2861	carbohydrate metabolic process
FK543_RS01425	COG4942	peptidase
FK543_RS01435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FK543_RS01440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FK543_RS01455	COG1045	serine acetyltransferase
FK543_RS01460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FK543_RS01470	COG2186	Transcriptional regulator
FK543_RS01475	COG1620	l-lactate permease
FK543_RS01480	COG5295	Hep Hag repeat protein
FK543_RS01505	COG3722	fumarate hydratase activity
FK543_RS01515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS01515	COG2213	PTS system mannitol-specific
FK543_RS01525	COG1566	PFAM secretion protein HlyD family protein
FK543_RS01545	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FK543_RS01555	COG0625	glutathione transferase activity
FK543_RS01565	COG3276	selenocysteine insertion sequence binding
FK543_RS01570	COG1454	alcohol dehydrogenase
FK543_RS01575	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS01590	COG1566	PFAM secretion protein HlyD family protein
FK543_RS01595	COG0583	DNA-binding transcription factor activity
FK543_RS01600	COG3713	MltA-interacting MipA family protein
FK543_RS01610	COG0235	Class ii aldolase
FK543_RS01615	COG3623	hexulose-6-phosphate isomerase
FK543_RS01620	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FK543_RS01625	COG1070	Carbohydrate kinase
FK543_RS01630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FK543_RS01635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FK543_RS01640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FK543_RS01645	COG2731	YhcH YjgK YiaL family protein
FK543_RS01655	COG1414	Transcriptional regulator
FK543_RS01660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS01665	COG3977	Valine--pyruvate aminotransferase
FK543_RS01670	COG0366	Alpha amylase catalytic
FK543_RS01675	COG2992	FlgJ-related protein
FK543_RS01680	COG1609	Transcriptional regulator
FK543_RS01680	COG2207	Transcriptional regulator
FK543_RS01685	COG4214	carbohydrate transport
FK543_RS01690	COG1129	ABC transporter
FK543_RS01695	COG4213	ABC transporter substrate-binding protein
FK543_RS01705	COG1070	Carbohydrate kinase
FK543_RS01710	COG4682	membrane
FK543_RS01715	COG4682	membrane
FK543_RS01720	COG3274	enterobacterial common antigen metabolic process
FK543_RS01745	COG1278	Cold shock
FK543_RS01750	COG2944	sequence-specific DNA binding
FK543_RS01765	COG2885	chlorophyll binding
FK543_RS01775	COG0456	acetyltransferase
FK543_RS01780	COG2818	Glycosylase
FK543_RS01785	COG5571	outer membrane autotransporter
FK543_RS01790	COG2223	nitrite transmembrane transporter activity
FK543_RS01820	COG2194	sulfuric ester hydrolase activity
FK543_RS01835	COG0747	negative chemotaxis
FK543_RS01845	COG0601	transmembrane transport
FK543_RS01850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FK543_RS01855	COG0444	Belongs to the ABC transporter superfamily
FK543_RS01860	COG4608	Belongs to the ABC transporter superfamily
FK543_RS01865	COG0814	amino acid
FK543_RS01900	COG2194	sulfuric ester hydrolase activity
FK543_RS01925	COG1215	transferase activity, transferring glycosyl groups
FK543_RS01930	COG1215	transferase activity, transferring glycosyl groups
FK543_RS01935	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FK543_RS01940	COG0457	Tetratricopeptide repeat
FK543_RS01940	COG3118	belongs to the thioredoxin family
FK543_RS01945	COG2199	diguanylate cyclase activity
FK543_RS01945	COG2200	EAL domain
FK543_RS01955	COG0612	Peptidase, M16
FK543_RS01965	COG2200	EAL domain
FK543_RS01970	COG2982	Protein involved in outer membrane biogenesis
FK543_RS01975	COG0477	Major facilitator Superfamily
FK543_RS01980	COG1295	ribonuclease BN
FK543_RS01985	COG0583	DNA-binding transcription factor activity
FK543_RS01990	COG2197	response regulator
FK543_RS02000	COG1858	cytochrome C peroxidase
FK543_RS02005	COG0076	glutamate decarboxylase activity
FK543_RS02015	COG2207	Transcriptional regulator
FK543_RS02020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK543_RS02025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK543_RS02035	COG2771	luxR family
FK543_RS02040	COG3247	response to pH
FK543_RS02055	COG1285	pathogenesis
FK543_RS02060	COG2197	response regulator
FK543_RS02065	COG3065	identical protein binding
FK543_RS02085	COG1393	Belongs to the ArsC family
FK543_RS02090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FK543_RS02095	COG0640	Transcriptional regulator
FK543_RS02105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK543_RS02110	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FK543_RS02115	COG0339	signal peptide processing
FK543_RS02125	COG3104	oligopeptide transport
FK543_RS02135	COG0589	response to stress
FK543_RS02145	COG0306	phosphate transporter
FK543_RS02150	COG2081	HI0933 family
FK543_RS02170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK543_RS02175	COG1129	ABC transporter
FK543_RS02175	COG0842	Transport permease protein
FK543_RS02180	COG0842	Transport permease protein
FK543_RS02205	COG0444	Belongs to the ABC transporter superfamily
FK543_RS02210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FK543_RS02215	COG0601	transmembrane transport
FK543_RS02220	COG0747	negative chemotaxis
FK543_RS02225	COG2091	lysine biosynthetic process via aminoadipic acid
FK543_RS02230	COG0628	permease
FK543_RS02245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FK543_RS02260	COG3714	YhhN family
FK543_RS02270	COG3776	membrane
FK543_RS02275	COG0742	ribosomal rna small subunit methyltransferase
FK543_RS02280	COG0552	protein localization to endoplasmic reticulum
FK543_RS02285	COG2884	Cell division ATP-binding protein ftsE
FK543_RS02290	COG2177	Part of the ABC transporter FtsEX involved in
FK543_RS02295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FK543_RS02300	COG0683	leucine binding
FK543_RS02305	COG0456	acetyltransferase
FK543_RS02310	COG0683	leucine binding
FK543_RS02315	COG0559	Belongs to the binding-protein-dependent transport system permease family
FK543_RS02320	COG4177	L-phenylalanine transmembrane transporter activity
FK543_RS02325	COG0411	ABC transporter
FK543_RS02330	COG0410	ABC transporter
FK543_RS02335	COG1653	transport
FK543_RS02340	COG1175	transmembrane transport
FK543_RS02345	COG0395	ABC-type sugar transport system, permease component
FK543_RS02355	COG0584	glycerophosphoryl diester phosphodiesterase
FK543_RS02365	COG0405	Gamma-glutamyltransferase
FK543_RS02390	COG3157	Type VI secretion system effector, Hcp
FK543_RS02395	COG1247	-acetyltransferase
FK543_RS02400	COG0673	inositol 2-dehydrogenase activity
FK543_RS02405	COG1741	Belongs to the pirin family
FK543_RS02410	COG1609	Transcriptional regulator
FK543_RS02415	COG3265	gluconokinase activity
FK543_RS02420	COG2610	gluconate transmembrane transporter activity
FK543_RS02425	COG2095	MarC family integral membrane protein
FK543_RS02430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FK543_RS02455	COG0058	SHG alpha-glucan phosphorylase activity
FK543_RS02460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FK543_RS02480	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FK543_RS02495	COG1349	DNA-binding transcription factor activity
FK543_RS02500	COG4650	regulator
FK543_RS02505	COG1690	Belongs to the RtcB family
FK543_RS02520	COG0058	SHG alpha-glucan phosphorylase activity
FK543_RS02525	COG1640	4-alpha-glucanotransferase
FK543_RS02530	COG2610	gluconate transmembrane transporter activity
FK543_RS02540	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS02555	COG1040	competence protein
FK543_RS02575	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FK543_RS02580	COG1918	ferrous iron import across plasma membrane
FK543_RS02585	COG2183	response to ionizing radiation
FK543_RS02590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FK543_RS02610	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FK543_RS02620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FK543_RS02625	COG1011	Hydrolase
FK543_RS02635	COG0494	nUDIX hydrolase
FK543_RS02640	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FK543_RS02645	COG4972	Pilus assembly protein
FK543_RS02650	COG3166	PFAM Fimbrial assembly family protein
FK543_RS02665	COG4796	Type ii and iii secretion system protein
FK543_RS02680	COG3266	domain, Protein
FK543_RS02685	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FK543_RS02690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FK543_RS02700	COG0180	Tryptophanyl-tRNA synthetase
FK543_RS02705	COG2188	Transcriptional regulator
FK543_RS02715	COG3457	Alanine racemase
FK543_RS02720	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FK543_RS02725	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FK543_RS02740	COG0626	cystathionine gamma-synthase activity
FK543_RS02755	COG2116	formate transmembrane transporter activity
FK543_RS02760	COG2146	nitrite reductase [NAD(P)H] activity
FK543_RS02765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK543_RS02775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FK543_RS02785	COG2184	nucleotidyltransferase activity
FK543_RS02790	COG0512	Glutamine amidotransferase of anthranilate synthase
FK543_RS02795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FK543_RS02800	COG1289	transmembrane transporter activity
FK543_RS02805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FK543_RS02810	COG1765	OsmC-like protein
FK543_RS02815	COG3954	Phosphoribulokinase
FK543_RS02825	COG0429	hydrolase of the alpha beta-hydrolase fold
FK543_RS02830	COG0488	(ABC) transporter
FK543_RS02845	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FK543_RS02850	COG1047	Peptidyl-prolyl cis-trans
FK543_RS02860	COG0545	Peptidyl-prolyl cis-trans isomerase
FK543_RS02865	COG2964	Protein conserved in bacteria
FK543_RS02935	COG0089	rRNA binding
FK543_RS03025	COG0201	protein transport
FK543_RS03065	COG0789	Transcriptional regulator
FK543_RS03070	COG3036	rescue of stalled ribosome
FK543_RS03080	COG0569	domain protein
FK543_RS03100	COG0758	DNA mediated transformation
FK543_RS03110	COG0551	DNA topoisomerase type I activity
FK543_RS03130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FK543_RS03175	COG1126	abc transporter atp-binding protein
FK543_RS03180	COG0765	amino acid transport
FK543_RS03185	COG4597	amino acid ABC transporter
FK543_RS03190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK543_RS03200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK543_RS03205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK543_RS03210	COG1309	transcriptional regulator
FK543_RS03220	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FK543_RS03230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FK543_RS03240	COG4145	pantothenate transmembrane transporter activity
FK543_RS03245	COG3924	membrane
FK543_RS03250	COG0439	Biotin carboxylase
FK543_RS03255	COG0511	ligase activity, forming carbon-carbon bonds
FK543_RS03260	COG0604	alcohol dehydrogenase
FK543_RS03265	COG2200	EAL domain
FK543_RS03265	COG2199	diguanylate cyclase activity
FK543_RS03270	COG1077	Cell shape determining protein MreB Mrl
FK543_RS03275	COG1792	Involved in formation and maintenance of cell shape
FK543_RS03280	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FK543_RS03290	COG1530	ribonuclease E activity
FK543_RS03295	COG3164	Protein of unknown function
FK543_RS03300	COG0312	modulator of DNA gyrase
FK543_RS03305	COG0583	DNA-binding transcription factor activity
FK543_RS03325	COG2732	(Barnase) inhibitor
FK543_RS03345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FK543_RS03350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FK543_RS03355	COG3105	Protein conserved in bacteria
FK543_RS03360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FK543_RS03380	COG0625	glutathione transferase activity
FK543_RS03385	COG2969	positive regulation of protein catabolic process
FK543_RS03390	COG3069	C4-dicarboxylate transmembrane transporter activity
FK543_RS03420	COG2731	YhcH YjgK YiaL family protein
FK543_RS03425	COG4804	nuclease activity
FK543_RS03430	COG0493	'glutamate synthase
FK543_RS03435	COG0069	glutamate synthase activity
FK543_RS03435	COG0067	glutamate synthase
FK543_RS03435	COG0070	glutamate synthase
FK543_RS03440	COG1242	4 iron, 4 sulfur cluster binding
FK543_RS03445	COG5002	protein histidine kinase activity
FK543_RS03445	COG2198	Histidine kinase
FK543_RS03445	COG0784	Response regulator, receiver
FK543_RS03450	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FK543_RS03460	COG0515	serine threonine protein kinase
FK543_RS03465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS03480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FK543_RS03485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FK543_RS03490	COG1137	ATPase activity
FK543_RS03495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FK543_RS03500	COG3117	lipopolysaccharide transmembrane transporter activity
FK543_RS03505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FK543_RS03510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FK543_RS03510	COG0517	IMP dehydrogenase activity
FK543_RS03515	COG0530	calcium, potassium:sodium antiporter activity
FK543_RS03520	COG1127	ABC transporter
FK543_RS03525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FK543_RS03530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FK543_RS03535	COG2854	intermembrane phospholipid transfer
FK543_RS03540	COG3113	response to antibiotic
FK543_RS03545	COG5007	Belongs to the BolA IbaG family
FK543_RS03555	COG3423	Transcriptional regulator
FK543_RS03560	COG0142	geranyltranstransferase activity
FK543_RS03575	COG0697	spore germination
FK543_RS03585	COG2027	D-alanyl-D-alanine carboxypeptidase
FK543_RS03590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FK543_RS03595	COG1534	Rna-binding protein
FK543_RS03605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FK543_RS03610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FK543_RS03620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FK543_RS03630	COG2194	sulfuric ester hydrolase activity
FK543_RS03650	COG0195	Participates in both transcription termination and antitermination
FK543_RS03690	COG0513	Belongs to the DEAD box helicase family
FK543_RS03695	COG0814	amino acid
FK543_RS03700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FK543_RS03705	COG0826	peptidase U32
FK543_RS03710	COG0826	peptidase U32
FK543_RS03715	COG3154	lipid carrier protein
FK543_RS03720	COG3153	acetyltransferase
FK543_RS03735	COG0693	protein deglycase activity
FK543_RS03740	COG0702	epimerase
FK543_RS03745	COG0701	Predicted permease
FK543_RS03750	COG2823	Periplasmic or secreted lipoprotein
FK543_RS03765	COG3107	peptidoglycan biosynthetic process
FK543_RS03770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FK543_RS03775	COG3539	Fimbrial protein
FK543_RS03780	COG3188	usher protein
FK543_RS03785	COG3121	Chaperone
FK543_RS03790	COG3539	Fimbrial protein
FK543_RS03795	COG0363	glucosamine-6-phosphate deaminase activity
FK543_RS03800	COG3716	PTS system mannose fructose sorbose family IID component
FK543_RS03805	COG3715	PTS system
FK543_RS03810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS03820	COG2222	sugar isomerase
FK543_RS03825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FK543_RS03830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS03835	COG3716	PTS system mannose fructose sorbose family IID component
FK543_RS03845	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS03855	COG1349	DNA-binding transcription factor activity
FK543_RS03865	COG2002	toxin-antitoxin pair type II binding
FK543_RS03870	COG2721	sulfolactate sulfo-lyase activity
FK543_RS03875	COG2271	Major facilitator Superfamily
FK543_RS03885	COG2084	Dehydrogenase
FK543_RS03890	COG1929	Belongs to the glycerate kinase type-1 family
FK543_RS03900	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS03925	COG0583	DNA-binding transcription factor activity
FK543_RS03930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FK543_RS03940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FK543_RS03945	COG1882	Formate acetyltransferase
FK543_RS03950	COG0251	oxidation-reduction process
FK543_RS03955	COG1760	l-serine dehydratase
FK543_RS03960	COG0814	amino acid
FK543_RS03975	COG1741	Belongs to the pirin family
FK543_RS03980	COG0583	DNA-binding transcription factor activity
FK543_RS03985	COG3152	Membrane
FK543_RS03990	COG3152	Membrane
FK543_RS03995	COG0435	Glutathione S-transferase
FK543_RS04000	COG2259	Doxx family
FK543_RS04010	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FK543_RS04015	COG4575	ribosome binding
FK543_RS04020	COG1422	Protein of unknown function (DUF1090)
FK543_RS04030	COG0586	Pfam SNARE associated Golgi protein
FK543_RS04035	COG2186	Transcriptional regulator
FK543_RS04060	COG2271	Major facilitator Superfamily
FK543_RS04070	COG2721	sulfolactate sulfo-lyase activity
FK543_RS04080	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FK543_RS04085	COG0861	Integral membrane protein TerC family
FK543_RS04090	COG0673	inositol 2-dehydrogenase activity
FK543_RS04095	COG2949	membrane
FK543_RS04100	COG1451	nucleotide metabolic process
FK543_RS04110	COG1902	pentaerythritol trinitrate reductase activity
FK543_RS04110	COG0446	pyridine nucleotide-disulphide oxidoreductase
FK543_RS04115	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FK543_RS04115	COG3408	Glycogen debranching enzyme
FK543_RS04125	COG0531	amino acid
FK543_RS04130	COG2731	YhcH YjgK YiaL family protein
FK543_RS04135	COG3250	beta-galactosidase activity
FK543_RS04140	COG1609	Transcriptional regulator
FK543_RS04145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FK543_RS04155	COG0840	transmembrane signaling receptor activity
FK543_RS04160	COG1695	Transcriptional regulator
FK543_RS04170	COG2375	cellular response to nickel ion
FK543_RS04185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FK543_RS04190	COG0358	DNA primase activity
FK543_RS04195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FK543_RS04205	COG0471	metal ion transport
FK543_RS04210	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FK543_RS04215	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FK543_RS04230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FK543_RS04245	COG4991	sh3 domain protein
FK543_RS04250	COG3025	triphosphatase activity
FK543_RS04275	COG2268	Band 7 protein
FK543_RS04280	COG1585	Membrane protein implicated in regulation of membrane protease activity
FK543_RS04290	COG3539	Fimbrial protein
FK543_RS04295	COG3121	Chaperone
FK543_RS04305	COG3539	Fimbrial protein
FK543_RS04310	COG2960	long-chain fatty acid transporting porin activity
FK543_RS04325	COG3384	dioxygenase
FK543_RS04330	COG0754	glutathionylspermidine amidase activity
FK543_RS04340	COG1538	Outer membrane efflux protein
FK543_RS04350	COG3151	Protein conserved in bacteria
FK543_RS04355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FK543_RS04360	COG3150	esterase
FK543_RS04365	COG0187	DNA topoisomerase II activity
FK543_RS04370	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FK543_RS04375	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK543_RS04385	COG0642	Histidine kinase
FK543_RS04390	COG0745	RESPONSE REGULATOR receiver
FK543_RS04395	COG3111	PFAM Bacterial OB fold (BOF) protein
FK543_RS04400	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FK543_RS04405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FK543_RS04410	COG0204	Acyl-transferase
FK543_RS04415	COG2132	Multicopper oxidase
FK543_RS04420	COG1032	radical SAM domain protein
FK543_RS04425	COG4238	major outer membrane lipoprotein
FK543_RS04435	COG0656	L-ascorbic acid biosynthetic process
FK543_RS04440	COG1979	alcohol dehydrogenase
FK543_RS04445	COG2207	Transcriptional regulator
FK543_RS04450	COG0586	Pfam SNARE associated Golgi protein
FK543_RS04455	COG0626	cystathionine gamma-synthase activity
FK543_RS04460	COG0811	peptide transport
FK543_RS04465	COG0848	biopolymer transport protein
FK543_RS04475	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS04490	COG0667	Aldo Keto reductase
FK543_RS04505	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FK543_RS04510	COG0437	4 iron, 4 sulfur cluster binding
FK543_RS04515	COG5557	Pfam Polysulphide reductase, NrfD
FK543_RS04520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FK543_RS04525	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FK543_RS04530	COG1773	rubredoxin
FK543_RS04535	COG0375	protein maturation
FK543_RS04540	COG0298	carbon dioxide binding
FK543_RS04545	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS04555	COG0625	glutathione transferase activity
FK543_RS04560	COG0754	glutathionylspermidine amidase activity
FK543_RS04565	COG0306	phosphate transporter
FK543_RS04570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FK543_RS04575	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FK543_RS04580	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FK543_RS04585	COG2244	polysaccharide biosynthetic process
FK543_RS04595	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FK543_RS04600	COG0795	lipopolysaccharide-transporting ATPase activity
FK543_RS04610	COG0156	8-amino-7-oxononanoate synthase activity
FK543_RS04615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FK543_RS04625	COG0318	PFAM AMP-dependent synthetase and ligase
FK543_RS04630	COG0456	acetyltransferase
FK543_RS04635	COG2186	Transcriptional regulator
FK543_RS04640	COG0277	FAD linked oxidase domain protein
FK543_RS04645	COG0277	FAD linked oxidase domain protein
FK543_RS04650	COG0247	lactate metabolic process
FK543_RS04655	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FK543_RS04660	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FK543_RS04665	COG1620	l-lactate permease
FK543_RS04680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FK543_RS04685	COG1459	type II secretion system
FK543_RS04690	COG2165	general secretion pathway protein
FK543_RS04720	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FK543_RS04730	COG1811	Na channel or pump
FK543_RS04735	COG1982	Orn Lys Arg decarboxylase major
FK543_RS04740	COG2211	Major facilitator Superfamily
FK543_RS04755	COG1194	a g-specific adenine glycosylase
FK543_RS04765	COG3171	Protein conserved in bacteria
FK543_RS04775	COG0252	asparaginase activity
FK543_RS04785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FK543_RS04800	COG0762	integral membrane protein
FK543_RS04805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FK543_RS04810	COG2805	Type II/IV secretion system protein
FK543_RS04825	COG0189	ligase activity
FK543_RS04830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FK543_RS04835	COG2356	endonuclease I
FK543_RS04845	COG2814	Major facilitator Superfamily
FK543_RS04860	COG1166	arginine decarboxylase activity
FK543_RS04885	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS04885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS04890	COG3715	PTS system
FK543_RS04895	COG3716	PTS system mannose fructose sorbose family IID component
FK543_RS04910	COG0501	Belongs to the peptidase M48B family
FK543_RS04915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FK543_RS04920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS04925	COG2213	PTS system mannitol-specific
FK543_RS04930	COG1063	alcohol dehydrogenase
FK543_RS04935	COG1494	fructose-1,6-bisphosphatase
FK543_RS04945	COG1072	(Pantothenic acid kinase))
FK543_RS04950	COG1122	ATPase activity
FK543_RS04955	COG1122	ATPase activity
FK543_RS04985	COG0191	fructose-bisphosphate aldolase activity
FK543_RS04990	COG0668	transmembrane transport
FK543_RS04995	COG1279	arginine transmembrane transporter activity
FK543_RS05000	COG2968	Membrane
FK543_RS05005	COG0583	DNA-binding transcription factor activity
FK543_RS05010	COG0427	acetyl-CoA hydrolase
FK543_RS05015	COG1024	Enoyl-CoA hydratase
FK543_RS05020	COG1703	isobutyryl-CoA mutase activity
FK543_RS05025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FK543_RS05025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FK543_RS05045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FK543_RS05060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FK543_RS05080	COG0006	proline dipeptidase activity
FK543_RS05085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK543_RS05090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK543_RS05115	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS05120	COG2723	6-phospho-beta-galactosidase activity
FK543_RS05130	COG1272	protein, Hemolysin III
FK543_RS05140	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FK543_RS05150	COG0716	FMN binding
FK543_RS05155	COG4974	Belongs to the 'phage' integrase family
FK543_RS05160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK543_RS05165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FK543_RS05195	COG2233	PERMEase
FK543_RS05200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS05200	COG0493	'glutamate synthase
FK543_RS05205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS05210	COG2252	PERMEase
FK543_RS05215	COG0402	S-adenosylhomocysteine deaminase activity
FK543_RS05220	COG2233	PERMEase
FK543_RS05225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FK543_RS05225	COG2080	2 iron, 2 sulfur cluster binding
FK543_RS05230	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FK543_RS05235	COG0402	S-adenosylhomocysteine deaminase activity
FK543_RS05240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS05240	COG0493	'glutamate synthase
FK543_RS05245	COG2068	MobA-Related Protein
FK543_RS05250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FK543_RS05255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FK543_RS05255	COG3608	succinylglutamate desuccinylase aspartoacylase
FK543_RS05260	COG0549	Belongs to the carbamate kinase family
FK543_RS05270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FK543_RS05275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FK543_RS05280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FK543_RS05285	COG3829	transcription factor binding
FK543_RS05290	COG2080	2 iron, 2 sulfur cluster binding
FK543_RS05295	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FK543_RS05300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FK543_RS05390	COG3387	PFAM Glycoside hydrolase 15-related
FK543_RS05500	COG0457	Tetratricopeptide repeat
FK543_RS05530	COG2771	luxR family
FK543_RS05535	COG0814	amino acid
FK543_RS05540	COG0183	Belongs to the thiolase family
FK543_RS05550	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS05555	COG2814	Major facilitator Superfamily
FK543_RS05560	COG1794	racemase activity, acting on amino acids and derivatives
FK543_RS05565	COG0583	DNA-binding transcription factor activity
FK543_RS05575	COG1609	Transcriptional regulator
FK543_RS05595	COG0667	Aldo Keto reductase
FK543_RS05605	COG0861	Integral membrane protein TerC family
FK543_RS05625	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FK543_RS05640	COG2165	general secretion pathway protein
FK543_RS05645	COG4795	General secretion pathway protein
FK543_RS05655	COG4967	type IV pilus modification protein PilV
FK543_RS05660	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FK543_RS05665	COG1025	Belongs to the peptidase M16 family
FK543_RS05670	COG1074	ATP-dependent DNA helicase activity
FK543_RS05675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FK543_RS05680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FK543_RS05680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FK543_RS05685	COG0860	N-Acetylmuramoyl-L-alanine amidase
FK543_RS05705	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FK543_RS05710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FK543_RS05715	COG2166	iron-sulfur cluster assembly
FK543_RS05720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FK543_RS05730	COG0583	DNA-binding transcription factor activity
FK543_RS05735	COG2363	Small membrane protein
FK543_RS05745	COG1349	DNA-binding transcription factor activity
FK543_RS05755	COG1070	Carbohydrate kinase
FK543_RS05765	COG0738	Major facilitator superfamily
FK543_RS05770	COG0235	Class ii aldolase
FK543_RS05775	COG1454	alcohol dehydrogenase
FK543_RS05785	COG1760	l-serine dehydratase
FK543_RS05790	COG0814	amino acid
FK543_RS05795	COG1611	Belongs to the LOG family
FK543_RS05810	COG3098	single-species biofilm formation
FK543_RS05815	COG0564	pseudouridine synthase activity
FK543_RS05820	COG0716	FMN binding
FK543_RS05825	COG2271	Major facilitator Superfamily
FK543_RS05830	COG4948	Mandelate Racemase Muconate Lactonizing
FK543_RS05835	COG4948	Mandelate Racemase Muconate Lactonizing
FK543_RS05840	COG3850	Histidine kinase
FK543_RS05840	COG3437	response regulator, receiver
FK543_RS05840	COG4999	Histidine kinase
FK543_RS05840	COG2205	protein histidine kinase activity
FK543_RS05850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FK543_RS05855	COG2336	PFAM SpoVT AbrB
FK543_RS05860	COG2337	Toxic component of a toxin-antitoxin (TA) module
FK543_RS05865	COG3956	TIGRFAM MazG family protein
FK543_RS05880	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FK543_RS05890	COG0602	queuosine metabolic process
FK543_RS05895	COG1070	Carbohydrate kinase
FK543_RS05900	COG2223	nitrite transmembrane transporter activity
FK543_RS05905	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS05910	COG0277	FAD linked oxidase domain protein
FK543_RS05915	COG0477	Major facilitator Superfamily
FK543_RS05920	COG2086	electron transfer activity
FK543_RS05925	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FK543_RS05930	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FK543_RS05935	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FK543_RS05940	COG0644	oxidoreductase
FK543_RS05945	COG0720	synthase
FK543_RS05975	COG1203	CRISPR-associated helicase, Cas3
FK543_RS05995	COG1857	crispr-associated protein
FK543_RS06010	COG1518	maintenance of DNA repeat elements
FK543_RS06015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK543_RS06020	COG2234	aminopeptidase activity
FK543_RS06075	COG4942	peptidase
FK543_RS06075	COG1388	LysM domain
FK543_RS06080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FK543_RS06095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FK543_RS06105	COG2610	gluconate transmembrane transporter activity
FK543_RS06110	COG3622	Belongs to the hyi family
FK543_RS06115	COG0235	Class ii aldolase
FK543_RS06120	COG3395	kinase activity
FK543_RS06125	COG2084	Dehydrogenase
FK543_RS06130	COG1349	DNA-binding transcription factor activity
FK543_RS06135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FK543_RS06150	COG3604	Transcriptional regulator
FK543_RS06155	COG0309	Hydrogenase expression formation protein (HypE)
FK543_RS06160	COG0409	Hydrogenase expression formation protein
FK543_RS06165	COG0298	carbon dioxide binding
FK543_RS06170	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FK543_RS06175	COG0375	protein maturation
FK543_RS06185	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS06190	COG0651	ATP synthesis coupled electron transport
FK543_RS06195	COG0650	Formate hydrogenlyase subunit 4
FK543_RS06200	COG3261	NADH dehydrogenase
FK543_RS06200	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FK543_RS06205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FK543_RS06210	COG3260	NADH ubiquinone oxidoreductase 20
FK543_RS06220	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FK543_RS06225	COG2723	6-phospho-beta-galactosidase activity
FK543_RS06230	COG1263	PTS System
FK543_RS06230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS06235	COG1609	Transcriptional regulator
FK543_RS06240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS06245	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FK543_RS06265	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FK543_RS06265	COG0517	IMP dehydrogenase activity
FK543_RS06270	COG1349	DNA-binding transcription factor activity
FK543_RS06275	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS06280	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS06290	COG3732	PTS system glucitol sorbitol-specific
FK543_RS06295	COG3730	PTS system glucitol sorbitol-specific
FK543_RS06300	COG2951	lytic endotransglycosylase activity
FK543_RS06305	COG1546	Belongs to the CinA family
FK543_RS06325	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FK543_RS06355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FK543_RS06360	COG1238	metal cluster binding
FK543_RS06375	COG2814	Major facilitator Superfamily
FK543_RS06380	COG1566	PFAM secretion protein HlyD family protein
FK543_RS06385	COG1846	Transcriptional regulator
FK543_RS06395	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FK543_RS06400	COG2814	Major facilitator Superfamily
FK543_RS06405	COG2113	Glycine betaine
FK543_RS06410	COG4176	ABC-type proline glycine betaine transport system permease component
FK543_RS06415	COG4175	Glycine betaine
FK543_RS06420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK543_RS06425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK543_RS06435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FK543_RS06440	COG4575	ribosome binding
FK543_RS06455	COG2916	Histone family protein nucleoid-structuring protein H-NS
FK543_RS06460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FK543_RS06465	COG0640	Transcriptional regulator
FK543_RS06470	COG0401	homolog of Blt101
FK543_RS06475	COG1652	LysM domain
FK543_RS06480	COG1802	Transcriptional regulator
FK543_RS06485	COG1113	amino acid transport
FK543_RS06490	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FK543_RS06495	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS06500	COG0579	oxidoreductase
FK543_RS06510	COG0366	Alpha amylase catalytic
FK543_RS06560	COG2867	negative regulation of translational initiation
FK543_RS06570	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK543_RS06575	COG0497	DNA recombination
FK543_RS06590	COG4536	flavin adenine dinucleotide binding
FK543_RS06595	COG4137	Cytochrome C assembly protein
FK543_RS06600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FK543_RS06625	COG2885	chlorophyll binding
FK543_RS06630	COG2199	diguanylate cyclase activity
FK543_RS06645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FK543_RS06650	COG0287	Prephenate dehydrogenase
FK543_RS06650	COG1605	Chorismate mutase
FK543_RS06655	COG1605	Chorismate mutase
FK543_RS06655	COG0077	Prephenate dehydratase
FK543_RS06665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FK543_RS06670	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK543_RS06675	COG0564	pseudouridine synthase activity
FK543_RS06680	COG1496	oxidoreductase activity
FK543_RS06685	COG0542	response to heat
FK543_RS06710	COG0477	Major facilitator Superfamily
FK543_RS06715	COG5544	Lipoprotein
FK543_RS06720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK543_RS06725	COG0045	succinate-CoA ligase (ADP-forming) activity
FK543_RS06725	COG1042	CoA-binding domain protein
FK543_RS06725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FK543_RS06730	COG3148	PFAM DTW domain containing protein
FK543_RS06735	COG3118	belongs to the thioredoxin family
FK543_RS06740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FK543_RS06765	COG0513	Belongs to the DEAD box helicase family
FK543_RS06775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FK543_RS06785	COG1595	DNA-templated transcription, initiation
FK543_RS06790	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FK543_RS06795	COG3026	antisigma factor binding
FK543_RS06800	COG3086	response to oxidative stress
FK543_RS06810	COG0681	Belongs to the peptidase S26 family
FK543_RS06830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FK543_RS06845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS06850	COG1737	Transcriptional regulator
FK543_RS06855	COG0560	Phosphoserine phosphatase
FK543_RS06870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FK543_RS06870	COG0047	phosphoribosylformylglycinamidine synthase activity
FK543_RS06875	COG2205	protein histidine kinase activity
FK543_RS06880	COG3170	Tfp pilus assembly protein FimV
FK543_RS06885	COG2204	response regulator
FK543_RS06890	COG0347	Belongs to the P(II) protein family
FK543_RS06895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK543_RS06895	COG1017	nitric oxide dioxygenase activity
FK543_RS06905	COG1940	carbohydrate kinase activity
FK543_RS06915	COG1879	ABC-type sugar transport system periplasmic component
FK543_RS06920	COG1129	ABC transporter
FK543_RS06925	COG1172	Belongs to the binding-protein-dependent transport system permease family
FK543_RS06930	COG1063	alcohol dehydrogenase
FK543_RS06935	COG2017	converts alpha-aldose to the beta-anomer
FK543_RS06940	COG2259	Doxx family
FK543_RS06965	COG4638	Rieske (2fe-2S)
FK543_RS06970	COG0583	DNA-binding transcription factor activity
FK543_RS06975	COG2814	Major facilitator Superfamily
FK543_RS06980	COG3711	transcriptional antiterminator
FK543_RS06985	COG1073	alpha beta
FK543_RS06990	COG0483	inositol monophosphate 1-phosphatase activity
FK543_RS07010	COG0822	iron-sulfur transferase activity
FK543_RS07030	COG0633	Ferredoxin
FK543_RS07035	COG2975	iron-sulfur cluster assembly
FK543_RS07050	COG2897	thiosulfate sulfurtransferase activity
FK543_RS07055	COG2373	Large extracellular alpha-helical protein
FK543_RS07060	COG4953	penicillin-binding protein 1C
FK543_RS07090	COG2976	Protein conserved in bacteria
FK543_RS07105	COG1645	bacterial-type flagellum-dependent swarming motility
FK543_RS07115	COG0516	GMP reductase activity
FK543_RS07115	COG0517	IMP dehydrogenase activity
FK543_RS07130	COG3133	Outer membrane lipoprotein
FK543_RS07140	COG2200	EAL domain
FK543_RS07145	COG0248	Ppx GppA phosphatase
FK543_RS07150	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FK543_RS07155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FK543_RS07170	COG2233	PERMEase
FK543_RS07180	COG1393	Belongs to the ArsC family
FK543_RS07185	COG4783	chaperone-mediated protein folding
FK543_RS07190	COG0628	permease
FK543_RS07195	COG2116	formate transmembrane transporter activity
FK543_RS07200	COG2116	formate transmembrane transporter activity
FK543_RS07205	COG3604	Transcriptional regulator
FK543_RS07215	COG3260	NADH ubiquinone oxidoreductase 20
FK543_RS07220	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FK543_RS07225	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FK543_RS07225	COG3261	NADH dehydrogenase
FK543_RS07235	COG4237	Hydrogenase 4 membrane
FK543_RS07245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FK543_RS07250	COG0650	Formate hydrogenlyase subunit 4
FK543_RS07260	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS07265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FK543_RS07270	COG2716	regulation of RNA biosynthetic process
FK543_RS07280	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FK543_RS07300	COG2321	neutral zinc metallopeptidase
FK543_RS07310	COG0400	carboxylic ester hydrolase activity
FK543_RS07325	COG1393	Belongs to the ArsC family
FK543_RS07335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK543_RS07340	COG3850	Histidine kinase
FK543_RS07345	COG0493	'glutamate synthase
FK543_RS07345	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS07355	COG5342	invasion associated locus B
FK543_RS07360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FK543_RS07365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FK543_RS07370	COG0280	phosphate acetyltransferase
FK543_RS07370	COG0281	malic enzyme
FK543_RS07375	COG4810	utilization protein
FK543_RS07380	COG4917	ethanolamine utilization protein
FK543_RS07385	COG4766	ethanolamine catabolic process
FK543_RS07390	COG4812	Cobalamin adenosyltransferase
FK543_RS07395	COG0280	phosphate acetyltransferase
FK543_RS07400	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FK543_RS07405	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FK543_RS07410	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS07415	COG4820	ethanolamine utilization protein (EutJ)
FK543_RS07420	COG1454	alcohol dehydrogenase
FK543_RS07425	COG3192	ethanolamine utilization protein
FK543_RS07430	COG4819	ethanolamine utilization protein
FK543_RS07435	COG4303	Ethanolamine ammonia lyase large subunit
FK543_RS07445	COG4816	utilization protein
FK543_RS07450	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FK543_RS07455	COG2207	Transcriptional regulator
FK543_RS07465	COG0860	N-Acetylmuramoyl-L-alanine amidase
FK543_RS07485	COG2837	iron assimilation
FK543_RS07490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FK543_RS07495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS07495	COG1263	PTS System
FK543_RS07510	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS07515	COG4150	thiosulfate binding
FK543_RS07520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FK543_RS07525	COG4208	sulfate ABC transporter
FK543_RS07530	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FK543_RS07535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FK543_RS07550	COG2190	(PTS) system
FK543_RS07555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FK543_RS07560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS07565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FK543_RS07585	COG3530	Putative quorum-sensing-regulated virulence factor
FK543_RS07590	COG0385	Bile acid
FK543_RS07595	COG0583	DNA-binding transcription factor activity
FK543_RS07605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FK543_RS07610	COG2211	Major facilitator Superfamily
FK543_RS07620	COG0583	DNA-binding transcription factor activity
FK543_RS07655	COG3415	Transposase
FK543_RS07660	COG3415	Transposase
FK543_RS07675	COG2199	diguanylate cyclase activity
FK543_RS07675	COG2200	EAL domain
FK543_RS07680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FK543_RS07705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK543_RS07710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK543_RS07715	COG0006	proline dipeptidase activity
FK543_RS07720	COG1363	Peptidase, m42
FK543_RS07730	COG2207	Transcriptional regulator
FK543_RS07735	COG3279	Response regulator of the LytR AlgR family
FK543_RS07740	COG3275	phosphorelay sensor kinase activity
FK543_RS07745	COG0436	Aminotransferase
FK543_RS07755	COG1560	Kdo2-lipid A biosynthetic process
FK543_RS07780	COG0028	Belongs to the TPP enzyme family
FK543_RS07785	COG0679	Auxin Efflux Carrier
FK543_RS07790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FK543_RS07795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK543_RS07795	COG2198	Histidine kinase
FK543_RS07795	COG2205	protein histidine kinase activity
FK543_RS07795	COG0784	Response regulator, receiver
FK543_RS07805	COG1566	PFAM secretion protein HlyD family protein
FK543_RS07810	COG0477	Major facilitator Superfamily
FK543_RS07945	COG4974	Belongs to the 'phage' integrase family
FK543_RS08040	COG3409	Peptidoglycan-binding domain 1 protein
FK543_RS08040	COG3429	Glucose-6-phosphate dehydrogenase subunit
FK543_RS08060	COG1475	DNA binding
FK543_RS08090	COG3422	double-strand break repair
FK543_RS08105	COG0582	viral genome integration into host DNA
FK543_RS08145	COG0582	viral genome integration into host DNA
FK543_RS08155	COG2116	formate transmembrane transporter activity
FK543_RS08160	COG2853	Lipoprotein
FK543_RS08170	COG2067	long-chain fatty acid transport protein
FK543_RS08175	COG3691	Protein conserved in bacteria
FK543_RS08190	COG2062	phosphohistidine phosphatase, SixA
FK543_RS08195	COG3539	Fimbrial protein
FK543_RS08200	COG3188	usher protein
FK543_RS08205	COG3121	Chaperone
FK543_RS08210	COG3539	Fimbrial protein
FK543_RS08220	COG3539	Fimbrial protein
FK543_RS08225	COG3539	Fimbrial protein
FK543_RS08240	COG2890	protein-(glutamine-N5) methyltransferase activity
FK543_RS08255	COG0730	response to heat
FK543_RS08260	COG3101	peptidyl-lysine hydroxylation
FK543_RS08275	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS08285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FK543_RS08290	COG2814	Major facilitator Superfamily
FK543_RS08305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FK543_RS08315	COG0586	Pfam SNARE associated Golgi protein
FK543_RS08325	COG0285	dihydrofolate synthase activity
FK543_RS08330	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FK543_RS08335	COG1286	toxin biosynthetic process
FK543_RS08340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FK543_RS08345	COG0163	prenyltransferase activity
FK543_RS08350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK543_RS08355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK543_RS08360	COG4215	(ABC) transporter
FK543_RS08365	COG4160	amino acid transport
FK543_RS08370	COG4598	ABC transporter
FK543_RS08375	COG5464	transposase or invertase
FK543_RS08380	COG1090	epimerase
FK543_RS08385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FK543_RS08390	COG0625	glutathione transferase activity
FK543_RS08395	COG0625	glutathione transferase activity
FK543_RS08400	COG0622	Phosphoesterase
FK543_RS08405	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FK543_RS08410	COG1288	antiporter activity
FK543_RS08415	COG0280	phosphate acetyltransferase
FK543_RS08415	COG0857	belongs to the CobB CobQ family
FK543_RS08420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FK543_RS08435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FK543_RS08440	COG0490	domain, Protein
FK543_RS08440	COG0471	metal ion transport
FK543_RS08450	COG0436	Aminotransferase
FK543_RS08455	COG0583	DNA-binding transcription factor activity
FK543_RS08475	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FK543_RS08480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FK543_RS08485	COG1034	ATP synthesis coupled electron transport
FK543_RS08500	COG0839	Belongs to the complex I subunit 6 family
FK543_RS08510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FK543_RS08515	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FK543_RS08545	COG2153	protein acetylation
FK543_RS08550	COG4575	ribosome binding
FK543_RS08555	COG1169	isochorismate synthase
FK543_RS08570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FK543_RS08580	COG0318	PFAM AMP-dependent synthetase and ligase
FK543_RS08650	COG5464	transposase or invertase
FK543_RS08655	COG0247	lactate metabolic process
FK543_RS08665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FK543_RS08670	COG2271	Major facilitator Superfamily
FK543_RS08675	COG0584	glycerophosphoryl diester phosphodiesterase
FK543_RS08685	COG3642	lipopolysaccharide core region biosynthetic process
FK543_RS08690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK543_RS08695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK543_RS08700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK543_RS08705	COG3468	outer membrane autotransporter barrel domain protein
FK543_RS08715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FK543_RS08720	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
FK543_RS08725	COG3234	Protein of unknown function (DUF1175)
FK543_RS08730	COG2373	Large extracellular alpha-helical protein
FK543_RS08735	COG5445	Predicted secreted protein (DUF2300)
FK543_RS08740	COG4676	Protein conserved in bacteria
FK543_RS08745	COG2205	protein histidine kinase activity
FK543_RS08745	COG0784	Response regulator, receiver
FK543_RS08750	COG2197	response regulator
FK543_RS08755	COG0642	Histidine kinase
FK543_RS08755	COG2198	Histidine kinase
FK543_RS08760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FK543_RS08765	COG1477	protein flavinylation
FK543_RS08770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FK543_RS08770	COG2169	Transcriptional regulator
FK543_RS08775	COG3145	DNA-N1-methyladenine dioxygenase activity
FK543_RS08780	COG4615	Cyclic peptide transporter
FK543_RS08795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS08795	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK543_RS08800	COG3062	negative regulation of establishment of protein localization
FK543_RS08810	COG0437	4 iron, 4 sulfur cluster binding
FK543_RS08815	COG0348	domain, Protein
FK543_RS08820	COG3043	anaerobic respiration
FK543_RS08825	COG3005	denitrification pathway
FK543_RS08830	COG4133	protoheme IX ABC transporter activity
FK543_RS08835	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FK543_RS08840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FK543_RS08845	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FK543_RS08855	COG1138	Cytochrome C-type biogenesis protein
FK543_RS08860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FK543_RS08865	COG4235	cytochrome complex assembly
FK543_RS08865	COG3088	subunit of a heme lyase
FK543_RS08870	COG2197	response regulator
FK543_RS08885	COG3083	sulfuric ester hydrolase activity
FK543_RS08905	COG1061	Type III restriction enzyme res subunit
FK543_RS08910	COG1187	pseudouridine synthase activity
FK543_RS08915	COG2814	Major facilitator Superfamily
FK543_RS08925	COG4172	Belongs to the ABC transporter superfamily
FK543_RS08930	COG4239	(ABC) transporter, permease
FK543_RS08935	COG4174	ABC transporter (Permease)
FK543_RS08940	COG4166	transmembrane transport
FK543_RS08945	COG2200	EAL domain
FK543_RS08950	COG0791	NLP P60 protein
FK543_RS08955	COG0671	phosphoesterase, PA-phosphatase related
FK543_RS08960	COG0523	cobalamin synthesis protein
FK543_RS08965	COG0246	Mannitol dehydrogenase
FK543_RS08980	COG2814	Major facilitator Superfamily
FK543_RS08985	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS08985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS08990	COG1105	Belongs to the carbohydrate kinase PfkB family
FK543_RS08995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK543_RS08995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK543_RS08995	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FK543_RS09000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FK543_RS09005	COG2313	pseudouridylate synthase activity
FK543_RS09010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FK543_RS09015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FK543_RS09025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FK543_RS09030	COG1522	sequence-specific DNA binding
FK543_RS09030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FK543_RS09040	COG2855	membrane
FK543_RS09045	COG0583	DNA-binding transcription factor activity
FK543_RS09050	COG0833	amino acid
FK543_RS09055	COG4771	TonB-dependent receptor
FK543_RS09070	COG2311	Membrane
FK543_RS09075	COG1609	Transcriptional regulator
FK543_RS09080	COG1879	ABC-type sugar transport system periplasmic component
FK543_RS09085	COG1129	ABC transporter
FK543_RS09090	COG4211	Belongs to the binding-protein-dependent transport system permease family
FK543_RS09095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FK543_RS09095	COG0167	dihydroorotate dehydrogenase activity
FK543_RS09100	COG0493	'glutamate synthase
FK543_RS09110	COG2949	membrane
FK543_RS09120	COG1346	cytolysis
FK543_RS09130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FK543_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS09150	COG0586	Pfam SNARE associated Golgi protein
FK543_RS09160	COG1686	Belongs to the peptidase S11 family
FK543_RS09165	COG0277	FAD linked oxidase domain protein
FK543_RS09170	COG1472	Belongs to the glycosyl hydrolase 3 family
FK543_RS09175	COG1732	Glycine betaine
FK543_RS09180	COG1174	glycine betaine transport
FK543_RS09185	COG1125	glycine betaine transport
FK543_RS09190	COG1174	glycine betaine transport
FK543_RS09200	COG0789	Transcriptional regulator
FK543_RS09205	COG3275	phosphorelay sensor kinase activity
FK543_RS09210	COG3279	Response regulator of the LytR AlgR family
FK543_RS09215	COG4807	Protein conserved in bacteria
FK543_RS09220	COG4808	Protein conserved in bacteria
FK543_RS09225	COG4715	Zinc finger, swim domain protein
FK543_RS09230	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FK543_RS09235	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FK543_RS09240	COG0714	Associated with various cellular activities
FK543_RS09250	COG3831	ATPase activity
FK543_RS09255	COG3831	ATPase activity
FK543_RS09265	COG0489	protein tyrosine kinase activity
FK543_RS09275	COG3539	Fimbrial protein
FK543_RS09280	COG3121	Chaperone
FK543_RS09285	COG3188	usher protein
FK543_RS09290	COG3539	Fimbrial protein
FK543_RS09295	COG5455	response to cobalt ion
FK543_RS09315	COG0351	phosphomethylpyrimidine kinase
FK543_RS09320	COG3757	hydrolase, family 25
FK543_RS09325	COG2188	Transcriptional regulator
FK543_RS09330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FK543_RS09335	COG1397	ADP-ribosylglycohydrolase
FK543_RS09340	COG2211	Major facilitator Superfamily
FK543_RS09345	COG1830	Aldolase
FK543_RS09360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS09365	COG3414	Phosphotransferase system galactitol-specific IIB component
FK543_RS09375	COG1063	alcohol dehydrogenase
FK543_RS09395	COG0826	peptidase U32
FK543_RS09405	COG3609	addiction module antidote protein, CC2985 family
FK543_RS09415	COG0745	RESPONSE REGULATOR receiver
FK543_RS09420	COG2205	protein histidine kinase activity
FK543_RS09460	COG4245	von Willebrand factor, type A
FK543_RS09465	COG0631	protein serine/threonine phosphatase activity
FK543_RS09470	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FK543_RS09475	COG0443	Heat shock 70 kDa protein
FK543_RS09480	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FK543_RS09485	COG5001	Diguanylate cyclase
FK543_RS09485	COG5002	protein histidine kinase activity
FK543_RS09485	COG3447	MASE1 domain protein
FK543_RS09490	COG0572	uridine kinase
FK543_RS09500	COG2982	Protein involved in outer membrane biogenesis
FK543_RS09505	COG1253	flavin adenine dinucleotide binding
FK543_RS09510	COG1596	polysaccharide export
FK543_RS09515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FK543_RS09520	COG0489	protein tyrosine kinase activity
FK543_RS09520	COG3206	protein involved in exopolysaccharide biosynthesis
FK543_RS09525	COG0463	Glycosyl transferase, family 2
FK543_RS09530	COG1045	serine acetyltransferase
FK543_RS09535	COG0438	transferase activity, transferring glycosyl groups
FK543_RS09545	COG1216	Glycosyl transferase, family 2
FK543_RS09550	COG0110	maltose O-acetyltransferase activity
FK543_RS09555	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FK543_RS09560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FK543_RS09565	COG1051	belongs to the nudix hydrolase family
FK543_RS09570	COG0297	glycogen (starch) synthase activity
FK543_RS09575	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FK543_RS09575	COG0662	Cupin 2, conserved barrel domain protein
FK543_RS09580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK543_RS09585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FK543_RS09590	COG2244	polysaccharide biosynthetic process
FK543_RS09595	COG2327	Polysaccharide pyruvyl transferase
FK543_RS09600	COG0438	transferase activity, transferring glycosyl groups
FK543_RS09610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FK543_RS09615	COG0367	asparagine synthase
FK543_RS09620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FK543_RS09620	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FK543_RS09645	COG1216	Glycosyl transferase, family 2
FK543_RS09655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FK543_RS09660	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FK543_RS09665	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FK543_RS09690	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FK543_RS09695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FK543_RS09695	COG0131	Imidazoleglycerol-phosphate dehydratase
FK543_RS09720	COG2161	toxin-antitoxin pair type II binding
FK543_RS09725	COG4115	mRNA cleavage
FK543_RS09730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FK543_RS09735	COG0583	DNA-binding transcription factor activity
FK543_RS09745	COG0531	amino acid
FK543_RS09750	COG2391	methyltransferase activity
FK543_RS09755	COG0425	Belongs to the sulfur carrier protein TusA family
FK543_RS09760	COG2925	Exonuclease
FK543_RS09765	COG1686	Belongs to the peptidase S11 family
FK543_RS09785	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS09815	COG4656	Part of a membrane complex involved in electron transport
FK543_RS09820	COG1454	alcohol dehydrogenase
FK543_RS09820	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS09835	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FK543_RS09850	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FK543_RS09910	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FK543_RS09925	COG1376	ErfK ybiS ycfS ynhG family protein
FK543_RS09935	COG0583	DNA-binding transcription factor activity
FK543_RS09940	COG0583	DNA-binding transcription factor activity
FK543_RS09950	COG0534	Mate efflux family protein
FK543_RS09960	COG0217	transcriptional regulatory protein
FK543_RS09965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FK543_RS09970	COG0477	Major facilitator Superfamily
FK543_RS10135	COG0523	cobalamin synthesis protein
FK543_RS10165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK543_RS10170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK543_RS10180	COG4372	Transposase
FK543_RS10185	COG3436	PFAM IS66 Orf2 family protein
FK543_RS10200	COG0803	Belongs to the bacterial solute-binding protein 9 family
FK543_RS10205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FK543_RS10215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FK543_RS10245	COG0803	Belongs to the bacterial solute-binding protein 9 family
FK543_RS10250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK543_RS10255	COG1121	(ABC) transporter
FK543_RS10265	COG0582	viral genome integration into host DNA
FK543_RS10285	COG3038	cytochrome b561
FK543_RS10290	COG3443	Belongs to the bacterial solute-binding protein 9 family
FK543_RS10305	COG2351	hydroxyisourate hydrolase activity
FK543_RS10310	COG0745	RESPONSE REGULATOR receiver
FK543_RS10315	COG2205	protein histidine kinase activity
FK543_RS10330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FK543_RS10340	COG1418	mRNA catabolic process
FK543_RS10345	COG0270	DNA (cytosine-5-)-methyltransferase activity
FK543_RS10350	COG3727	T/G mismatch-specific endonuclease activity
FK543_RS10355	COG0697	spore germination
FK543_RS10360	COG2354	Protein conserved in bacteria
FK543_RS10365	COG5475	Uncharacterized small protein (DUF2158)
FK543_RS10370	COG3706	GGDEF domain
FK543_RS10395	COG2197	response regulator
FK543_RS10400	COG1684	flagellar biosynthetic protein fliR
FK543_RS10405	COG1987	bacterial-type flagellum assembly
FK543_RS10410	COG1338	Plays a role in the flagellum-specific transport system
FK543_RS10415	COG3190	flagellar
FK543_RS10420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FK543_RS10425	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FK543_RS10430	COG1580	Controls the rotational direction of flagella during chemotaxis
FK543_RS10435	COG3144	bacterial-type flagellum assembly
FK543_RS10440	COG2882	bacterial-type flagellum organization
FK543_RS10445	COG1157	protein secretion by the type III secretion system
FK543_RS10450	COG1317	bacterial-type flagellum organization
FK543_RS10455	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FK543_RS10460	COG1766	The M ring may be actively involved in energy transduction
FK543_RS10470	COG2076	Multidrug Resistance protein
FK543_RS10475	COG1881	PFAM PEBP family protein
FK543_RS10480	COG2207	Transcriptional regulator
FK543_RS10495	COG0675	Transposase, IS605 OrfB family
FK543_RS10500	COG2135	peptidase activity
FK543_RS10505	COG0425	Belongs to the sulfur carrier protein TusA family
FK543_RS10510	COG2391	methyltransferase activity
FK543_RS10520	COG0366	Alpha amylase catalytic
FK543_RS10530	COG1516	flagellar protein fliS
FK543_RS10545	COG1191	sigma factor activity
FK543_RS10555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK543_RS10565	COG0765	amino acid transport
FK543_RS10570	COG1126	abc transporter atp-binding protein
FK543_RS10575	COG2197	response regulator
FK543_RS10590	COG2197	response regulator
FK543_RS10620	COG3012	SEC-C Motif Domain Protein
FK543_RS10620	COG3318	Belongs to the UPF0149 family
FK543_RS10625	COG0814	amino acid
FK543_RS10635	COG1528	Iron-storage protein
FK543_RS10655	COG1528	Iron-storage protein
FK543_RS10660	COG1879	ABC-type sugar transport system periplasmic component
FK543_RS10665	COG1129	ABC transporter
FK543_RS10670	COG1172	Belongs to the binding-protein-dependent transport system permease family
FK543_RS10675	COG1877	trehalose-phosphatase activity
FK543_RS10685	COG0589	response to stress
FK543_RS10700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FK543_RS10705	COG1360	Flagellar Motor Protein
FK543_RS10710	COG2198	Histidine kinase
FK543_RS10710	COG0643	Histidine kinase
FK543_RS10715	COG0835	chemotaxis
FK543_RS10720	COG0840	transmembrane signaling receptor activity
FK543_RS10725	COG0840	transmembrane signaling receptor activity
FK543_RS10730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FK543_RS10735	COG2201	protein-glutamate methylesterase activity
FK543_RS10740	COG0745	RESPONSE REGULATOR receiver
FK543_RS10745	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FK543_RS10750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FK543_RS10755	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FK543_RS10765	COG3755	Protein conserved in bacteria
FK543_RS10775	COG3102	Protein conserved in bacteria
FK543_RS10785	COG3005	denitrification pathway
FK543_RS10790	COG0243	molybdopterin cofactor binding
FK543_RS10805	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FK543_RS10810	COG1801	Protein of unknown function DUF72
FK543_RS10815	COG1335	isochorismatase
FK543_RS10825	COG0494	nUDIX hydrolase
FK543_RS10830	COG0217	transcriptional regulatory protein
FK543_RS10860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK543_RS10870	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FK543_RS10875	COG0739	heme binding
FK543_RS10880	COG1560	Kdo2-lipid A biosynthetic process
FK543_RS10900	COG3842	ATPase activity
FK543_RS10910	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FK543_RS10920	COG2182	Extracellular solute-binding protein
FK543_RS10925	COG1175	transmembrane transport
FK543_RS10930	COG3833	ABC-type maltose transport systems, permease component
FK543_RS10960	COG0469	pyruvate kinase activity
FK543_RS10965	COG1737	Transcriptional regulator
FK543_RS10970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FK543_RS10975	COG0129	dihydroxy-acid dehydratase activity
FK543_RS10980	COG0800	Aldolase
FK543_RS10990	COG3141	response to X-ray
FK543_RS11000	COG2979	Protein of unknown function (DUF533)
FK543_RS11005	COG1770	oligopeptidase
FK543_RS11010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK543_RS11015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FK543_RS11025	COG2372	response to copper ion
FK543_RS11040	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FK543_RS11060	COG3008	intermembrane lipid transfer
FK543_RS11065	COG2995	paraquat-inducible protein a
FK543_RS11070	COG1956	GAF domain-containing protein
FK543_RS11080	COG0793	Belongs to the peptidase S41A family
FK543_RS11090	COG2814	Major facilitator Superfamily
FK543_RS11095	COG1414	Transcriptional regulator
FK543_RS11125	COG2226	methyltransferase
FK543_RS11140	COG3716	PTS system mannose fructose sorbose family IID component
FK543_RS11145	COG3715	PTS system
FK543_RS11150	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS11150	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS11160	COG2200	EAL domain
FK543_RS11165	COG1760	l-serine dehydratase
FK543_RS11175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FK543_RS11190	COG0251	oxidation-reduction process
FK543_RS11195	COG1199	ATP-dependent helicase activity
FK543_RS11200	COG1214	PFAM Peptidase M22, glycoprotease
FK543_RS11205	COG3065	identical protein binding
FK543_RS11210	COG0318	PFAM AMP-dependent synthetase and ligase
FK543_RS11215	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FK543_RS11220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK543_RS11225	COG4638	Rieske (2fe-2S)
FK543_RS11230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK543_RS11235	COG0473	3-isopropylmalate dehydrogenase activity
FK543_RS11240	COG0583	DNA-binding transcription factor activity
FK543_RS11255	COG0675	Transposase, IS605 OrfB family
FK543_RS11260	COG2261	transglycosylase associated protein
FK543_RS11275	COG2203	Gaf domain
FK543_RS11275	COG2199	diguanylate cyclase activity
FK543_RS11280	COG3042	response to heat
FK543_RS11285	COG3189	MarR family transcriptional regulator
FK543_RS11290	COG2807	transmembrane transport
FK543_RS11295	COG2207	Transcriptional regulator
FK543_RS11310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FK543_RS11315	COG2199	diguanylate cyclase activity
FK543_RS11320	COG2199	diguanylate cyclase activity
FK543_RS11330	COG2766	serine protein kinase
FK543_RS11335	COG3713	MltA-interacting MipA family protein
FK543_RS11340	COG0656	L-ascorbic acid biosynthetic process
FK543_RS11345	COG0676	glucose-6-phosphate 1-epimerase activity
FK543_RS11350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FK543_RS11360	COG3139	Protein of unknown function (DUF1315)
FK543_RS11365	COG1335	isochorismatase
FK543_RS11370	COG0252	asparaginase activity
FK543_RS11375	COG0616	signal peptide processing
FK543_RS11380	COG0778	Nitroreductase
FK543_RS11390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FK543_RS11400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FK543_RS11410	COG0494	nUDIX hydrolase
FK543_RS11415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FK543_RS11420	COG2897	thiosulfate sulfurtransferase activity
FK543_RS11425	COG4136	ATPase activity
FK543_RS11430	COG4135	transport system, permease component
FK543_RS11435	COG4134	Bacterial extracellular solute-binding protein
FK543_RS11440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FK543_RS11445	COG0398	Pfam SNARE associated Golgi protein
FK543_RS11455	COG0398	Pfam SNARE associated Golgi protein
FK543_RS11460	COG0708	Exodeoxyribonuclease III
FK543_RS11490	COG3678	ATP-independent chaperone mediated protein folding
FK543_RS11500	COG0322	excinuclease ABC activity
FK543_RS11510	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK543_RS11515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FK543_RS11520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FK543_RS11525	COG1447	Phosphotransferase system cellobiose-specific component IIA
FK543_RS11530	COG2169	Transcriptional regulator
FK543_RS11530	COG1917	Cupin 2, conserved barrel domain protein
FK543_RS11535	COG1486	melibiose metabolic process
FK543_RS11545	COG0753	catalase activity
FK543_RS11560	COG1823	symporter activity
FK543_RS11565	COG1988	membrane-bound metal-dependent
FK543_RS11570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FK543_RS11580	COG3001	Fructosamine kinase
FK543_RS11590	COG1105	Belongs to the carbohydrate kinase PfkB family
FK543_RS11595	COG3137	Salt-induced outer membrane protein
FK543_RS11655	COG0386	Belongs to the glutathione peroxidase family
FK543_RS11665	COG0791	NLP P60 protein
FK543_RS11670	COG2200	EAL domain
FK543_RS11680	COG4256	Hemin uptake protein
FK543_RS11685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FK543_RS11695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FK543_RS11695	COG0574	Belongs to the PEP-utilizing enzyme family
FK543_RS11700	COG0318	PFAM AMP-dependent synthetase and ligase
FK543_RS11705	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FK543_RS11710	COG0644	oxidoreductase
FK543_RS11715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FK543_RS11720	COG2086	electron transfer activity
FK543_RS11725	COG1917	Cupin 2, conserved barrel domain protein
FK543_RS11725	COG2207	Transcriptional regulator
FK543_RS11730	COG1960	acyl-CoA dehydrogenase activity
FK543_RS11735	COG4670	ketone body catabolic process
FK543_RS11750	COG2271	Major facilitator Superfamily
FK543_RS11755	COG0738	Major facilitator superfamily
FK543_RS11770	COG0628	permease
FK543_RS11775	COG0247	lactate metabolic process
FK543_RS11775	COG0277	FAD linked oxidase domain protein
FK543_RS11780	COG2050	protein possibly involved in aromatic compounds catabolism
FK543_RS11790	COG0316	Belongs to the HesB IscA family
FK543_RS11795	COG0719	Fe-S assembly protein
FK543_RS11800	COG0396	ATPase activity
FK543_RS11805	COG0719	Fe-S assembly protein
FK543_RS11820	COG1376	ErfK ybiS ycfS ynhG family protein
FK543_RS11825	COG4238	major outer membrane lipoprotein
FK543_RS11830	COG0469	pyruvate kinase activity
FK543_RS11840	COG0437	4 iron, 4 sulfur cluster binding
FK543_RS11845	COG2414	aldehyde ferredoxin oxidoreductase
FK543_RS11855	COG0437	4 iron, 4 sulfur cluster binding
FK543_RS11860	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FK543_RS11870	COG4529	Protein conserved in bacteria
FK543_RS11890	COG3468	outer membrane autotransporter barrel domain protein
FK543_RS11900	COG0307	riboflavin synthase, alpha
FK543_RS11905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FK543_RS11910	COG2814	Major facilitator Superfamily
FK543_RS11915	COG0583	DNA-binding transcription factor activity
FK543_RS11930	COG2814	Major facilitator Superfamily
FK543_RS11935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FK543_RS11940	COG0791	NLP P60 protein
FK543_RS11945	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FK543_RS11960	COG0346	lactoylglutathione lyase activity
FK543_RS11965	COG1902	pentaerythritol trinitrate reductase activity
FK543_RS11970	COG1309	transcriptional regulator
FK543_RS11975	COG3313	Fe-S protein
FK543_RS11980	COG4989	oxidoreductase activity
FK543_RS11985	COG2032	superoxide dismutase activity
FK543_RS11990	COG1289	transmembrane transporter activity
FK543_RS11995	COG1566	PFAM secretion protein HlyD family protein
FK543_RS12010	COG3133	Outer membrane lipoprotein
FK543_RS12020	COG3895	Periplasmic Protein
FK543_RS12035	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FK543_RS12040	COG0625	glutathione transferase activity
FK543_RS12045	COG3104	oligopeptide transport
FK543_RS12050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FK543_RS12060	COG4659	FMN binding
FK543_RS12100	COG0673	inositol 2-dehydrogenase activity
FK543_RS12110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FK543_RS12115	COG1263	PTS System
FK543_RS12115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS12120	COG1609	Transcriptional regulator
FK543_RS12125	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS12130	COG1309	transcriptional regulator
FK543_RS12135	COG3250	beta-galactosidase activity
FK543_RS12150	COG5339	Protein conserved in bacteria
FK543_RS12155	COG1482	cell wall glycoprotein biosynthetic process
FK543_RS12160	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FK543_RS12160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FK543_RS12165	COG0114	fumarate hydratase activity
FK543_RS12175	COG2205	protein histidine kinase activity
FK543_RS12180	COG0745	RESPONSE REGULATOR receiver
FK543_RS12185	COG3136	membrane protein required for alginate biosynthesis
FK543_RS12195	COG0531	amino acid
FK543_RS12205	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FK543_RS12210	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FK543_RS12235	COG3591	Belongs to the peptidase S1B family
FK543_RS12250	COG2814	Major facilitator Superfamily
FK543_RS12255	COG0583	DNA-binding transcription factor activity
FK543_RS12260	COG1940	carbohydrate kinase activity
FK543_RS12265	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FK543_RS12275	COG3381	protein complex oligomerization
FK543_RS12280	COG3302	dmso reductase anchor subunit
FK543_RS12285	COG0437	4 iron, 4 sulfur cluster binding
FK543_RS12290	COG0243	molybdopterin cofactor binding
FK543_RS12295	COG0243	molybdopterin cofactor binding
FK543_RS12310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FK543_RS12325	COG4948	Mandelate Racemase Muconate Lactonizing
FK543_RS12330	COG1063	alcohol dehydrogenase
FK543_RS12340	COG0582	viral genome integration into host DNA
FK543_RS12395	COG1403	HNH endonuclease
FK543_RS12400	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FK543_RS12405	COG0484	heat shock protein binding
FK543_RS12435	COG3064	Membrane
FK543_RS12460	COG3772	lysozyme
FK543_RS12470	COG5301	cellulose 1,4-beta-cellobiosidase activity
FK543_RS12475	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FK543_RS12490	COG0477	Major facilitator Superfamily
FK543_RS12495	COG0246	Mannitol dehydrogenase
FK543_RS12505	COG1802	Transcriptional regulator
FK543_RS12510	COG4221	oxidoreductase activity
FK543_RS12515	COG0339	signal peptide processing
FK543_RS12520	COG1546	Belongs to the CinA family
FK543_RS12525	COG3111	PFAM Bacterial OB fold (BOF) protein
FK543_RS12530	COG3706	GGDEF domain
FK543_RS12540	COG2814	Major facilitator Superfamily
FK543_RS12545	COG0697	spore germination
FK543_RS12550	COG2188	Transcriptional regulator
FK543_RS12560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FK543_RS12565	COG1447	Phosphotransferase system cellobiose-specific component IIA
FK543_RS12575	COG2723	6-phospho-beta-galactosidase activity
FK543_RS12585	COG4977	sequence-specific DNA binding
FK543_RS12590	COG1846	Transcriptional regulator
FK543_RS12615	COG0583	DNA-binding transcription factor activity
FK543_RS12620	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS12625	COG2066	Belongs to the glutaminase family
FK543_RS12635	COG2199	diguanylate cyclase activity
FK543_RS12695	COG2911	Protein conserved in bacteria
FK543_RS12695	COG3210	domain, Protein
FK543_RS12705	COG1396	sequence-specific DNA binding
FK543_RS12710	COG3550	peptidyl-serine autophosphorylation
FK543_RS12720	COG3539	Fimbrial protein
FK543_RS12740	COG3188	usher protein
FK543_RS12745	COG3539	Fimbrial protein
FK543_RS12750	COG3539	Fimbrial protein
FK543_RS12755	COG3539	Fimbrial protein
FK543_RS12760	COG0243	molybdopterin cofactor binding
FK543_RS12770	COG2207	Transcriptional regulator
FK543_RS12775	COG3119	arylsulfatase activity
FK543_RS12780	COG0641	radical SAM
FK543_RS12790	COG4178	(ABC) transporter
FK543_RS12795	COG4771	TonB-dependent receptor
FK543_RS12800	COG0612	Peptidase, M16
FK543_RS12805	COG0076	glutamate decarboxylase activity
FK543_RS12810	COG0531	amino acid
FK543_RS12815	COG1649	PFAM Uncharacterised BCR, COG1649
FK543_RS12825	COG2202	Pas domain
FK543_RS12825	COG2199	diguanylate cyclase activity
FK543_RS12825	COG2200	EAL domain
FK543_RS12830	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FK543_RS12835	COG0747	negative chemotaxis
FK543_RS12840	COG0601	transmembrane transport
FK543_RS12845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FK543_RS12850	COG0444	Belongs to the ABC transporter superfamily
FK543_RS12855	COG4608	Belongs to the ABC transporter superfamily
FK543_RS12860	COG1764	response to oxidative stress
FK543_RS12880	COG1064	alcohol dehydrogenase
FK543_RS12885	COG3093	addiction module antidote protein HigA
FK543_RS12890	COG2864	formate dehydrogenase
FK543_RS12895	COG0437	4 iron, 4 sulfur cluster binding
FK543_RS12905	COG0697	spore germination
FK543_RS12910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FK543_RS12915	COG4886	Leucine-rich repeat (LRR) protein
FK543_RS12920	COG2223	nitrite transmembrane transporter activity
FK543_RS12925	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FK543_RS12930	COG1140	nitrate reductase beta subunit
FK543_RS12935	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FK543_RS12940	COG2181	nitrate reductase activity
FK543_RS12945	COG0384	phenazine biosynthesis protein PhzF
FK543_RS12950	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FK543_RS12955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK543_RS12975	COG3209	COG3209 Rhs family protein
FK543_RS12985	COG0625	glutathione transferase activity
FK543_RS12990	COG1113	amino acid transport
FK543_RS12995	COG3391	amine dehydrogenase activity
FK543_RS13005	COG1802	Transcriptional regulator
FK543_RS13010	COG2130	NADP-dependent
FK543_RS13015	COG1247	-acetyltransferase
FK543_RS13020	COG3238	Protein conserved in bacteria
FK543_RS13050	COG1177	transmembrane transport
FK543_RS13055	COG1176	ABC-type spermidine putrescine transport system, permease component I
FK543_RS13060	COG3842	ATPase activity
FK543_RS13065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FK543_RS13070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK543_RS13075	COG1598	PFAM Uncharacterised protein family UPF0150
FK543_RS13080	COG1724	mRNA binding
FK543_RS13090	COG0826	peptidase U32
FK543_RS13095	COG1396	sequence-specific DNA binding
FK543_RS13100	COG3135	benzoate transporter
FK543_RS13105	COG0675	Transposase, IS605 OrfB family
FK543_RS13120	COG0500	methyltransferase
FK543_RS13125	COG1275	C4-dicarboxylate transporter malic acid transport protein
FK543_RS13130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FK543_RS13135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FK543_RS13140	COG2841	Protein conserved in bacteria
FK543_RS13150	COG5383	Protein conserved in bacteria
FK543_RS13155	COG0583	DNA-binding transcription factor activity
FK543_RS13160	COG0840	transmembrane signaling receptor activity
FK543_RS13175	COG3038	cytochrome b561
FK543_RS13180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FK543_RS13185	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS13190	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FK543_RS13195	COG1643	Atp-dependent helicase
FK543_RS13205	COG0671	phosphoesterase, PA-phosphatase related
FK543_RS13205	COG2453	phosphatase
FK543_RS13210	COG2267	carboxylic ester hydrolase activity
FK543_RS13215	COG4589	Belongs to the CDS family
FK543_RS13220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FK543_RS13230	COG0667	Aldo Keto reductase
FK543_RS13235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FK543_RS13240	COG3327	negative regulation of DNA-templated transcription, initiation
FK543_RS13245	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FK543_RS13250	COG0183	Belongs to the thiolase family
FK543_RS13255	COG2050	protein possibly involved in aromatic compounds catabolism
FK543_RS13260	COG1250	3-hydroxyacyl-CoA dehydrogenase
FK543_RS13265	COG1024	Enoyl-CoA hydratase
FK543_RS13270	COG1024	Enoyl-CoA hydratase
FK543_RS13275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK543_RS13280	COG2151	metal-sulfur cluster biosynthetic enzyme
FK543_RS13285	COG3396	Phenylacetate-CoA oxygenase
FK543_RS13290	COG3460	Phenylacetate-CoA oxygenase
FK543_RS13295	COG3396	Phenylacetate-CoA oxygenase
FK543_RS13300	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS13300	COG2030	dehydratase
FK543_RS13305	COG3733	amine oxidase
FK543_RS13310	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS13315	COG2207	Transcriptional regulator
FK543_RS13320	COG3784	Protein of unknown function (DUF1318)
FK543_RS13330	COG2911	Protein conserved in bacteria
FK543_RS13335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FK543_RS13340	COG3187	Heat shock protein
FK543_RS13345	COG3042	response to heat
FK543_RS13350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FK543_RS13350	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FK543_RS13350	COG1013	pyruvate-flavodoxin oxidoreductase activity
FK543_RS13350	COG0674	pyruvate-flavodoxin oxidoreductase activity
FK543_RS13355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FK543_RS13360	COG0589	response to stress
FK543_RS13370	COG1121	(ABC) transporter
FK543_RS13375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK543_RS13380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK543_RS13390	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FK543_RS13395	COG5301	cellulose 1,4-beta-cellobiosidase activity
FK543_RS13400	COG1475	DNA binding
FK543_RS13405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FK543_RS13415	COG3772	lysozyme
FK543_RS13455	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FK543_RS13470	COG1846	Transcriptional regulator
FK543_RS13475	COG1484	DNA-dependent DNA replication
FK543_RS13535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK543_RS13540	COG3723	Recombinational DNA repair protein, rece pathway
FK543_RS13560	COG0582	viral genome integration into host DNA
FK543_RS13570	COG0513	Belongs to the DEAD box helicase family
FK543_RS13580	COG3706	GGDEF domain
FK543_RS13585	COG2840	Smr protein MutS2
FK543_RS13590	COG0583	DNA-binding transcription factor activity
FK543_RS13595	COG1473	amidohydrolase
FK543_RS13600	COG1473	amidohydrolase
FK543_RS13605	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FK543_RS13610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FK543_RS13615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FK543_RS13620	COG0589	response to stress
FK543_RS13625	COG3182	Iron-regulated membrane protein
FK543_RS13630	COG0668	transmembrane transport
FK543_RS13640	COG0583	DNA-binding transcription factor activity
FK543_RS13645	COG1073	alpha beta
FK543_RS13650	COG1073	alpha beta
FK543_RS13655	COG0702	epimerase
FK543_RS13660	COG2866	Carboxypeptidase
FK543_RS13665	COG4948	Mandelate Racemase Muconate Lactonizing
FK543_RS13670	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FK543_RS13675	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FK543_RS13685	COG3106	COG3106 Predicted ATPase
FK543_RS13690	COG1609	Transcriptional regulator
FK543_RS13700	COG3842	ATPase activity
FK543_RS13705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FK543_RS13710	COG1554	hydrolase, family 65, central catalytic
FK543_RS13715	COG0673	inositol 2-dehydrogenase activity
FK543_RS13720	COG1082	Xylose isomerase domain protein TIM barrel
FK543_RS13725	COG1063	alcohol dehydrogenase
FK543_RS13730	COG0395	ABC-type sugar transport system, permease component
FK543_RS13735	COG1175	transmembrane transport
FK543_RS13740	COG1653	transport
FK543_RS13745	COG0366	Alpha amylase catalytic
FK543_RS13750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FK543_RS13760	COG1983	PspC domain protein
FK543_RS13770	COG1842	Phage shock protein A
FK543_RS13775	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FK543_RS13780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FK543_RS13785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FK543_RS13790	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS13795	COG1917	Cupin 2, conserved barrel domain protein
FK543_RS13795	COG1396	sequence-specific DNA binding
FK543_RS13800	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FK543_RS13805	COG0174	glutamine synthetase
FK543_RS13815	COG0531	amino acid
FK543_RS13825	COG4166	transmembrane transport
FK543_RS13830	COG4168	peptide transport system, permease
FK543_RS13835	COG4171	peptide transport system, permease
FK543_RS13840	COG4172	Belongs to the ABC transporter superfamily
FK543_RS13845	COG4172	Belongs to the ABC transporter superfamily
FK543_RS13850	COG2852	Protein conserved in bacteria
FK543_RS13855	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FK543_RS13860	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FK543_RS13860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FK543_RS13875	COG5001	Diguanylate cyclase
FK543_RS13885	COG1349	DNA-binding transcription factor activity
FK543_RS13895	COG0023	Translation Initiation Factor
FK543_RS13905	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FK543_RS13910	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FK543_RS13915	COG0671	phosphoesterase, PA-phosphatase related
FK543_RS13925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FK543_RS13945	COG0583	DNA-binding transcription factor activity
FK543_RS13950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FK543_RS13960	COG0616	signal peptide processing
FK543_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS13970	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FK543_RS13975	COG1187	pseudouridine synthase activity
FK543_RS13980	COG0009	L-threonylcarbamoyladenylate synthase
FK543_RS13985	COG0613	PHP domain protein
FK543_RS13995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FK543_RS14000	COG0512	Glutamine amidotransferase of anthranilate synthase
FK543_RS14000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FK543_RS14005	COG0135	phosphoribosylanthranilate isomerase activity
FK543_RS14005	COG0134	indole-3-glycerol-phosphate synthase activity
FK543_RS14020	COG3729	General stress protein
FK543_RS14025	COG3685	Protein conserved in bacteria
FK543_RS14030	COG3685	Protein conserved in bacteria
FK543_RS14035	COG3047	cAMP biosynthetic process
FK543_RS14055	COG1607	acyl-coa hydrolase
FK543_RS14065	COG2350	Protein conserved in bacteria
FK543_RS14070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FK543_RS14090	COG4608	Belongs to the ABC transporter superfamily
FK543_RS14095	COG0444	Belongs to the ABC transporter superfamily
FK543_RS14100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FK543_RS14105	COG0601	transmembrane transport
FK543_RS14110	COG4166	transmembrane transport
FK543_RS14115	COG2095	MarC family integral membrane protein
FK543_RS14120	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS14120	COG1454	alcohol dehydrogenase
FK543_RS14130	COG1435	thymidine kinase activity
FK543_RS14140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FK543_RS14145	COG0745	RESPONSE REGULATOR receiver
FK543_RS14150	COG1752	Esterase of the alpha-beta hydrolase superfamily
FK543_RS14160	COG0788	formyltetrahydrofolate deformylase activity
FK543_RS14180	COG2181	nitrate reductase activity
FK543_RS14185	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FK543_RS14190	COG1140	nitrate reductase beta subunit
FK543_RS14195	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FK543_RS14200	COG2223	nitrite transmembrane transporter activity
FK543_RS14205	COG3850	Histidine kinase
FK543_RS14210	COG2197	response regulator
FK543_RS14215	COG4932	domain protein
FK543_RS14220	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FK543_RS14225	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FK543_RS14230	COG4572	Cation transport regulator
FK543_RS14235	COG0387	Pfam Sodium calcium exchanger
FK543_RS14285	COG2912	Transglutaminase-like superfamily
FK543_RS14290	COG3094	Invasion gene expression up-regulator, SirB
FK543_RS14295	COG2890	protein-(glutamine-N5) methyltransferase activity
FK543_RS14320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FK543_RS14325	COG0659	secondary active sulfate transmembrane transporter activity
FK543_RS14340	COG0012	GTP binding
FK543_RS14345	COG3468	outer membrane autotransporter barrel domain protein
FK543_RS14350	COG3284	Transcriptional regulator
FK543_RS14355	COG2376	Dihydroxyacetone kinase
FK543_RS14360	COG1461	Dihydroxyacetone kinase
FK543_RS14365	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FK543_RS14365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS14365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FK543_RS14385	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FK543_RS14395	COG1619	proteins homologs of microcin C7 resistance protein MccF
FK543_RS14405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FK543_RS14415	COG2719	SpoVR family
FK543_RS14430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FK543_RS14440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FK543_RS14455	COG0179	Fumarylacetoacetate (FAA) hydrolase
FK543_RS14480	COG2894	cell division
FK543_RS14535	COG2200	EAL domain
FK543_RS14565	COG0789	Transcriptional regulator
FK543_RS14570	COG5562	phage envelope protein
FK543_RS14585	COG0538	isocitrate dehydrogenase activity
FK543_RS14590	COG1187	pseudouridine synthase activity
FK543_RS14610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FK543_RS14620	COG2205	protein histidine kinase activity
FK543_RS14625	COG2850	peptidyl-arginine hydroxylation
FK543_RS14645	COG1177	transmembrane transport
FK543_RS14650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FK543_RS14660	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FK543_RS14665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FK543_RS14675	COG4591	ABC-type transport system involved in lipoprotein release permease component
FK543_RS14680	COG1136	(ABC) transporter
FK543_RS14685	COG4591	ABC-type transport system involved in lipoprotein release permease component
FK543_RS14690	COG4763	Acyl-transferase
FK543_RS14695	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FK543_RS14700	COG1388	LysM domain
FK543_RS14700	COG1376	ErfK ybiS ycfS ynhG family protein
FK543_RS14710	COG1309	transcriptional regulator
FK543_RS14715	COG3134	Outer membrane lipoprotein
FK543_RS14720	COG1252	NADH dehydrogenase
FK543_RS14740	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FK543_RS14745	COG5633	Lipoprotein
FK543_RS14750	COG0537	adenosine 5'-monophosphoramidase activity
FK543_RS14755	COG4773	Receptor
FK543_RS14760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS14760	COG1263	PTS System
FK543_RS14765	COG0084	hydrolase, TatD family'
FK543_RS14770	COG0470	DNA polymerase III
FK543_RS14780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FK543_RS14785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FK543_RS14790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FK543_RS14800	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS14805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FK543_RS14825	COG1399	metal-binding, possibly nucleic acid-binding protein
FK543_RS14830	COG0424	maF-like protein
FK543_RS14835	COG0564	pseudouridine synthase activity
FK543_RS14840	COG1530	ribonuclease E activity
FK543_RS14845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FK543_RS14850	COG1256	bacterial-type flagellum assembly
FK543_RS14855	COG1705	Flagellar rod assembly protein muramidase FlgJ
FK543_RS14855	COG3951	Flagellar rod assembly protein muramidase FlgJ
FK543_RS14870	COG4786	Flagellar basal body rod
FK543_RS14875	COG4787	bacterial-type flagellum-dependent cell motility
FK543_RS14880	COG1749	Flagellar hook protein flgE
FK543_RS14885	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FK543_RS14890	COG1558	bacterial-type flagellum-dependent cell motility
FK543_RS14895	COG1815	bacterial-type flagellum-dependent cell motility
FK543_RS14900	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FK543_RS14905	COG2747	anti-sigma28 factor FlgM
FK543_RS14910	COG3418	PFAM FlgN family protein
FK543_RS14915	COG0728	peptidoglycan biosynthetic process
FK543_RS14920	COG0673	inositol 2-dehydrogenase activity
FK543_RS14930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FK543_RS14940	COG2999	glutathione oxidoreductase activity
FK543_RS14975	COG3038	cytochrome b561
FK543_RS14980	COG2353	YceI-like domain
FK543_RS14990	COG1560	Kdo2-lipid A biosynthetic process
FK543_RS15005	COG5645	(Lipo)protein
FK543_RS15010	COG2943	transferase activity, transferring hexosyl groups
FK543_RS15025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK543_RS15030	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FK543_RS15055	COG2197	response regulator
FK543_RS15070	COG1462	curli production assembly transport component CsgG
FK543_RS15080	COG3381	protein complex oligomerization
FK543_RS15120	COG3706	GGDEF domain
FK543_RS15125	COG0457	Tetratricopeptide repeat
FK543_RS15130	COG0726	polysaccharide deacetylase
FK543_RS15130	COG1649	PFAM Uncharacterised BCR, COG1649
FK543_RS15135	COG1215	transferase activity, transferring glycosyl groups
FK543_RS15140	COG3658	cytochrome
FK543_RS15145	COG1702	phosphate starvation-inducible protein PhoH
FK543_RS15150	COG2837	iron assimilation
FK543_RS15155	COG2822	iron ion transport
FK543_RS15165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FK543_RS15175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK543_RS15175	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK543_RS15175	COG0506	proline dehydrogenase activity
FK543_RS15180	COG1309	transcriptional regulator
FK543_RS15215	COG2233	PERMEase
FK543_RS15220	COG3729	General stress protein
FK543_RS15260	COG0243	molybdopterin cofactor binding
FK543_RS15265	COG3005	denitrification pathway
FK543_RS15270	COG0745	RESPONSE REGULATOR receiver
FK543_RS15275	COG1879	ABC-type sugar transport system periplasmic component
FK543_RS15280	COG2205	protein histidine kinase activity
FK543_RS15280	COG2198	Histidine kinase
FK543_RS15280	COG0784	Response regulator, receiver
FK543_RS15285	COG0348	domain, Protein
FK543_RS15305	COG1278	Cold shock
FK543_RS15310	COG1278	Cold shock
FK543_RS15330	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK543_RS15335	COG1596	polysaccharide export
FK543_RS15340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FK543_RS15345	COG3206	protein involved in exopolysaccharide biosynthesis
FK543_RS15345	COG0489	protein tyrosine kinase activity
FK543_RS15360	COG1294	oxidase, subunit
FK543_RS15365	COG1271	oxidase subunit
FK543_RS15370	COG1773	rubredoxin
FK543_RS15375	COG1999	signal sequence binding
FK543_RS15380	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FK543_RS15385	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FK543_RS15390	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FK543_RS15395	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FK543_RS15405	COG0670	Belongs to the BI1 family
FK543_RS15410	COG2920	part of a sulfur-relay system
FK543_RS15415	COG1254	Belongs to the acylphosphatase family
FK543_RS15430	COG1832	CoA-binding protein
FK543_RS15445	COG0210	DNA helicase
FK543_RS15450	COG3304	Inner membrane component domain
FK543_RS15455	COG1289	transmembrane transporter activity
FK543_RS15460	COG3070	regulator of competence-specific genes
FK543_RS15470	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FK543_RS15470	COG2885	chlorophyll binding
FK543_RS15480	COG1067	ATP-dependent peptidase activity
FK543_RS15490	COG3130	regulation of translation
FK543_RS15495	COG3009	Protein conserved in bacteria
FK543_RS15500	COG3008	intermembrane lipid transfer
FK543_RS15500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FK543_RS15505	COG2995	paraquat-inducible protein a
FK543_RS15510	COG0488	(ABC) transporter
FK543_RS15520	COG3217	Mosc domain protein beta barrel domain protein
FK543_RS15520	COG0633	Ferredoxin
FK543_RS15535	COG3121	Chaperone
FK543_RS15540	COG3539	Fimbrial protein
FK543_RS15545	COG3539	Fimbrial protein
FK543_RS15550	COG3539	Fimbrial protein
FK543_RS15555	COG3188	usher protein
FK543_RS15560	COG3121	Chaperone
FK543_RS15565	COG3539	Fimbrial protein
FK543_RS15570	COG0431	NADPH-dependent FMN reductase
FK543_RS15575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK543_RS15585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FK543_RS15595	COG0308	aminopeptidase N
FK543_RS15615	COG1448	Aminotransferase
FK543_RS15620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK543_RS15625	COG3108	Peptidase M15
FK543_RS15630	COG2989	Protein conserved in bacteria
FK543_RS15640	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FK543_RS15650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FK543_RS15655	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FK543_RS15660	COG3173	Aminoglycoside phosphotransferase
FK543_RS15675	COG3214	Protein conserved in bacteria
FK543_RS15685	COG1132	(ABC) transporter
FK543_RS15690	COG0658	competence protein
FK543_RS15690	COG2333	competence protein COMEC
FK543_RS15700	COG0539	negative regulation of cytoplasmic translation
FK543_RS15710	COG0501	Belongs to the peptidase M48B family
FK543_RS15725	COG2323	membrane
FK543_RS15730	COG1944	ATP diphosphatase activity
FK543_RS15735	COG2116	formate transmembrane transporter activity
FK543_RS15740	COG1882	Formate acetyltransferase
FK543_RS15745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FK543_RS15750	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK543_RS15755	COG0583	DNA-binding transcription factor activity
FK543_RS15760	COG0531	amino acid
FK543_RS15770	COG1335	isochorismatase
FK543_RS15775	COG3302	dmso reductase anchor subunit
FK543_RS15780	COG0437	4 iron, 4 sulfur cluster binding
FK543_RS15785	COG0243	molybdopterin cofactor binding
FK543_RS15795	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FK543_RS15810	COG1522	sequence-specific DNA binding
FK543_RS15815	COG0492	ferredoxin-NADP+ reductase activity
FK543_RS15820	COG4988	ABC transporter
FK543_RS15825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FK543_RS15850	COG0542	response to heat
FK543_RS15860	COG1278	Cold shock
FK543_RS15870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK543_RS15875	COG2990	Protein conserved in bacteria
FK543_RS15880	COG3593	DNA synthesis involved in DNA repair
FK543_RS15885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FK543_RS15895	COG2431	L-lysine efflux transmembrane transporter activity
FK543_RS15905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK543_RS15910	COG0028	Belongs to the TPP enzyme family
FK543_RS15915	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FK543_RS15920	COG0702	epimerase
FK543_RS15925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FK543_RS15930	COG3023	N-Acetylmuramoyl-L-alanine amidase
FK543_RS15945	COG1126	abc transporter atp-binding protein
FK543_RS15950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK543_RS15955	COG4215	(ABC) transporter
FK543_RS15960	COG4160	amino acid transport
FK543_RS15965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK543_RS15980	COG1177	transmembrane transport
FK543_RS15985	COG1176	ABC-type spermidine putrescine transport system, permease component I
FK543_RS15990	COG3842	ATPase activity
FK543_RS15995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FK543_RS16010	COG0778	Nitroreductase
FK543_RS16020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FK543_RS16035	COG3226	Transcriptional regulator
FK543_RS16040	COG0738	Major facilitator superfamily
FK543_RS16045	COG0561	phosphatase activity
FK543_RS16055	COG2814	Major facilitator Superfamily
FK543_RS16060	COG0671	phosphoesterase, PA-phosphatase related
FK543_RS16065	COG1349	DNA-binding transcription factor activity
FK543_RS16070	COG1686	Belongs to the peptidase S11 family
FK543_RS16075	COG0625	glutathione transferase activity
FK543_RS16080	COG2133	pyrroloquinoline quinone binding
FK543_RS16095	COG2199	diguanylate cyclase activity
FK543_RS16100	COG2200	EAL domain
FK543_RS16125	COG1446	asparaginase
FK543_RS16130	COG0303	'Molybdopterin
FK543_RS16135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FK543_RS16140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FK543_RS16145	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FK543_RS16150	COG1882	Formate acetyltransferase
FK543_RS16155	COG0561	phosphatase activity
FK543_RS16165	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS16175	COG0488	(ABC) transporter
FK543_RS16180	COG1376	ErfK ybiS ycfS ynhG family protein
FK543_RS16185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FK543_RS16190	COG1321	iron dependent repressor
FK543_RS16200	COG2194	sulfuric ester hydrolase activity
FK543_RS16205	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FK543_RS16215	COG5006	permease, DMT superfamily
FK543_RS16225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK543_RS16230	COG0765	amino acid transport
FK543_RS16235	COG1126	abc transporter atp-binding protein
FK543_RS16240	COG0668	transmembrane transport
FK543_RS16255	COG4774	siderophore transport
FK543_RS16265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FK543_RS16280	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS16290	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FK543_RS16295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FK543_RS16300	COG1199	ATP-dependent helicase activity
FK543_RS16305	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FK543_RS16310	COG0513	Belongs to the DEAD box helicase family
FK543_RS16315	COG1309	transcriptional regulator
FK543_RS16325	COG1131	(ABC) transporter
FK543_RS16330	COG0842	Transport permease protein
FK543_RS16335	COG0842	Transport permease protein
FK543_RS16345	COG3568	Endonuclease Exonuclease Phosphatase
FK543_RS16350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK543_RS16355	COG0392	lysyltransferase activity
FK543_RS16360	COG0670	Belongs to the BI1 family
FK543_RS16370	COG0670	Belongs to the BI1 family
FK543_RS16375	COG0314	molybdopterin synthase activity
FK543_RS16380	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FK543_RS16390	COG0521	Mo-molybdopterin cofactor biosynthetic process
FK543_RS16400	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FK543_RS16410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FK543_RS16415	COG2226	methyltransferase
FK543_RS16430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FK543_RS16435	COG1881	PFAM PEBP family protein
FK543_RS16440	COG4677	pectinesterase activity
FK543_RS16445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FK543_RS16450	COG0471	metal ion transport
FK543_RS16455	COG2828	Protein conserved in bacteria
FK543_RS16460	COG0583	DNA-binding transcription factor activity
FK543_RS16470	COG0561	phosphatase activity
FK543_RS16480	COG4149	molybdate abc transporter
FK543_RS16485	COG0725	ABC transporter, periplasmic molybdate-binding protein
FK543_RS16495	COG2005	Transcriptional regulator
FK543_RS16495	COG3585	molybdate ion transport
FK543_RS16500	COG1119	ATPase activity
FK543_RS16505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FK543_RS16510	COG1085	galactose-1-phosphate uridylyltransferase
FK543_RS16520	COG2017	converts alpha-aldose to the beta-anomer
FK543_RS16530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FK543_RS16540	COG1230	cation diffusion facilitator family transporter
FK543_RS16545	COG3201	nicotinamide mononucleotide transporter
FK543_RS16590	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FK543_RS16595	COG2885	chlorophyll binding
FK543_RS16605	COG3064	Membrane
FK543_RS16610	COG0848	biopolymer transport protein
FK543_RS16615	COG0811	peptide transport
FK543_RS16620	COG0824	Thioesterase
FK543_RS16625	COG3790	cyd operon protein YbgE
FK543_RS16630	COG4890	Cyd operon protein YbgT
FK543_RS16635	COG1294	oxidase, subunit
FK543_RS16640	COG1271	oxidase subunit
FK543_RS16645	COG0383	alpha-mannosidase activity
FK543_RS16655	COG2188	Transcriptional regulator
FK543_RS16660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FK543_RS16670	COG0508	dehydrogenase complex catalyzes the overall conversion of
FK543_RS16675	COG0567	Dehydrogenase, E1 component
FK543_RS16680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FK543_RS16685	COG1053	succinate dehydrogenase
FK543_RS16690	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FK543_RS16695	COG2009	succinate dehydrogenase
FK543_RS16705	COG0372	Belongs to the citrate synthase family
FK543_RS16710	COG3539	Fimbrial protein
FK543_RS16715	COG3188	usher protein
FK543_RS16720	COG3121	Chaperone
FK543_RS16725	COG3539	Fimbrial protein
FK543_RS16730	COG3180	Ammonia monooxygenase
FK543_RS16745	COG1984	allophanate hydrolase subunit 2
FK543_RS16750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FK543_RS16755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FK543_RS16765	COG0415	Belongs to the DNA photolyase family
FK543_RS16770	COG3272	Protein of unknown function (DUF1722)
FK543_RS16790	COG3209	COG3209 Rhs family protein
FK543_RS16820	COG2205	protein histidine kinase activity
FK543_RS16825	COG0745	RESPONSE REGULATOR receiver
FK543_RS16840	COG1982	Orn Lys Arg decarboxylase major
FK543_RS16845	COG0531	amino acid
FK543_RS16850	COG0033	Phosphoglucomutase
FK543_RS16855	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FK543_RS16860	COG0596	Alpha beta hydrolase
FK543_RS16870	COG0716	FMN binding
FK543_RS16880	COG0735	belongs to the Fur family
FK543_RS16900	COG2190	(PTS) system
FK543_RS16900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS16900	COG1263	PTS System
FK543_RS16910	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FK543_RS16915	COG1940	carbohydrate kinase activity
FK543_RS16915	COG1846	Transcriptional regulator
FK543_RS16920	COG0647	UMP catabolic process
FK543_RS16925	COG0367	asparagine synthase
FK543_RS16965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK543_RS16975	COG1702	phosphate starvation-inducible protein PhoH
FK543_RS16985	COG4535	Mg2 and Co2 transporter CorC
FK543_RS16990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FK543_RS17005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK543_RS17010	COG0765	amino acid transport
FK543_RS17015	COG0765	amino acid transport
FK543_RS17020	COG1126	abc transporter atp-binding protein
FK543_RS17030	COG0443	Heat shock 70 kDa protein
FK543_RS17035	COG2214	Heat shock protein DnaJ domain protein
FK543_RS17045	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FK543_RS17050	COG2214	Heat shock protein DnaJ domain protein
FK543_RS17060	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FK543_RS17065	COG2888	peptidyl-tyrosine sulfation
FK543_RS17080	COG1466	dna polymerase III delta subunit
FK543_RS17090	COG0406	alpha-ribazole phosphatase activity
FK543_RS17095	COG0799	negative regulation of ribosome biogenesis
FK543_RS17105	COG0768	penicillin binding
FK543_RS17110	COG0772	Belongs to the SEDS family
FK543_RS17115	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FK543_RS17120	COG1686	Belongs to the peptidase S11 family
FK543_RS17135	COG0583	DNA-binding transcription factor activity
FK543_RS17145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FK543_RS17150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FK543_RS17170	COG3069	C4-dicarboxylate transmembrane transporter activity
FK543_RS17175	COG4565	transcriptional regulatory protein
FK543_RS17180	COG3290	protein histidine kinase activity
FK543_RS17185	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FK543_RS17195	COG2301	Belongs to the HpcH HpaI aldolase family
FK543_RS17200	COG3051	citrate lyase alpha subunit
FK543_RS17215	COG0471	metal ion transport
FK543_RS17220	COG3719	Belongs to the RNase T2 family
FK543_RS17225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FK543_RS17230	COG1063	alcohol dehydrogenase
FK543_RS17235	COG0589	response to stress
FK543_RS17240	COG3634	alkyl hydroperoxide reductase activity
FK543_RS17245	COG0450	alkyl hydroperoxide reductase
FK543_RS17250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK543_RS17255	COG0583	DNA-binding transcription factor activity
FK543_RS17260	COG3969	phosphoadenosine phosphosulfate
FK543_RS17265	COG1475	DNA binding
FK543_RS17270	COG0436	Aminotransferase
FK543_RS17275	COG0371	Dehydrogenase
FK543_RS17280	COG2879	small protein
FK543_RS17285	COG1966	Carbon starvation protein
FK543_RS17290	COG2050	protein possibly involved in aromatic compounds catabolism
FK543_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS17300	COG3433	isochorismatase activity
FK543_RS17300	COG1535	isochorismatase
FK543_RS17305	COG1021	2,3-dihydroxybenzoate-AMP ligase
FK543_RS17310	COG1169	isochorismate synthase
FK543_RS17315	COG4592	Periplasmic binding protein
FK543_RS17325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FK543_RS17330	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FK543_RS17335	COG1120	ATPase activity
FK543_RS17340	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FK543_RS17345	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FK543_RS17345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK543_RS17350	COG3251	PFAM MbtH domain protein
FK543_RS17355	COG2382	esterase
FK543_RS17360	COG4771	TonB-dependent receptor
FK543_RS17365	COG2977	Belongs to the P-Pant transferase superfamily
FK543_RS17400	COG2315	Protein conserved in bacteria
FK543_RS17405	COG0778	Nitroreductase
FK543_RS17410	COG0668	transmembrane transport
FK543_RS17415	COG1113	amino acid transport
FK543_RS17420	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK543_RS17425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK543_RS17430	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK543_RS17435	COG1538	Outer membrane efflux protein
FK543_RS17440	COG0745	RESPONSE REGULATOR receiver
FK543_RS17445	COG5002	protein histidine kinase activity
FK543_RS17465	COG1215	transferase activity, transferring glycosyl groups
FK543_RS17470	COG4783	chaperone-mediated protein folding
FK543_RS17485	COG4571	Outer membrane protease
FK543_RS17500	COG0500	methyltransferase
FK543_RS17515	COG4220	transposase activity
FK543_RS17535	COG5562	phage envelope protein
FK543_RS17550	COG3772	lysozyme
FK543_RS17570	COG1403	HNH endonuclease
FK543_RS17580	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FK543_RS17595	COG1846	Transcriptional regulator
FK543_RS17620	COG0582	viral genome integration into host DNA
FK543_RS17630	COG2197	response regulator
FK543_RS17635	COG3539	Fimbrial protein
FK543_RS17640	COG3539	Fimbrial protein
FK543_RS17645	COG3188	usher protein
FK543_RS17650	COG3121	Chaperone
FK543_RS17655	COG3539	Fimbrial protein
FK543_RS17665	COG2501	S4 domain
FK543_RS17670	COG1988	membrane-bound metal-dependent
FK543_RS17680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FK543_RS17690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FK543_RS17695	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FK543_RS17700	COG0549	Belongs to the carbamate kinase family
FK543_RS17710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FK543_RS17715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FK543_RS17720	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FK543_RS17725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FK543_RS17730	COG3257	ureidoglycine aminohydrolase activity
FK543_RS17735	COG1929	Belongs to the glycerate kinase type-1 family
FK543_RS17740	COG2233	PERMEase
FK543_RS17750	COG1953	Uracil, thiamine, allantoin
FK543_RS17755	COG2084	Dehydrogenase
FK543_RS17760	COG3622	Belongs to the hyi family
FK543_RS17765	COG3960	tartronate-semialdehyde synthase activity
FK543_RS17770	COG1414	Transcriptional regulator
FK543_RS17780	COG0583	DNA-binding transcription factor activity
FK543_RS17800	COG3209	COG3209 Rhs family protein
FK543_RS17810	COG3209	COG3209 Rhs family protein
FK543_RS17815	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FK543_RS17820	COG4181	ATPase activity
FK543_RS17825	COG2755	lipolytic protein G-D-S-L family
FK543_RS17830	COG0300	oxidoreductase activity
FK543_RS17835	COG3118	belongs to the thioredoxin family
FK543_RS17840	COG0390	transport system, permease component
FK543_RS17845	COG4619	ABC transporter
FK543_RS17850	COG0330	HflC and HflK could
FK543_RS17855	COG1585	Membrane protein implicated in regulation of membrane protease activity
FK543_RS17860	COG0789	Transcriptional regulator
FK543_RS17865	COG0531	amino acid
FK543_RS17870	COG2066	Belongs to the glutaminase family
FK543_RS17875	COG2217	Heavy metal translocating P-type atpase
FK543_RS17880	COG3093	addiction module antidote protein HigA
FK543_RS17890	COG3735	TraB family
FK543_RS17895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FK543_RS17905	COG2223	nitrite transmembrane transporter activity
FK543_RS17910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FK543_RS17910	COG4651	solute:proton antiporter activity
FK543_RS17915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FK543_RS17955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FK543_RS17965	COG2832	Protein of unknown function (DUF454)
FK543_RS17970	COG3923	Primosomal replication protein n
FK543_RS17980	COG1196	nuclear chromosome segregation
FK543_RS17980	COG3264	Mechanosensitive ion channel
FK543_RS17985	COG1309	transcriptional regulator
FK543_RS17990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK543_RS17995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK543_RS18010	COG0110	maltose O-acetyltransferase activity
FK543_RS18020	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FK543_RS18025	COG5507	3-demethylubiquinone-9 3-methyltransferase
FK543_RS18035	COG3695	enzyme binding
FK543_RS18040	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FK543_RS18045	COG1946	Acyl-CoA thioesterase
FK543_RS18050	COG0004	ammonium transporteR
FK543_RS18055	COG0347	Belongs to the P(II) protein family
FK543_RS18060	COG1132	(ABC) transporter
FK543_RS18065	COG1132	(ABC) transporter
FK543_RS18070	COG1522	sequence-specific DNA binding
FK543_RS18080	COG4533	DNA binding
FK543_RS18090	COG0824	Thioesterase
FK543_RS18095	COG1555	photosystem II stabilization
FK543_RS18100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FK543_RS18105	COG0776	regulation of translation
FK543_RS18110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FK543_RS18130	COG0271	Belongs to the BolA IbaG family
FK543_RS18135	COG3056	Lipoprotein
FK543_RS18140	COG2223	nitrite transmembrane transporter activity
FK543_RS18145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FK543_RS18150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FK543_RS18155	COG1845	cytochrome c oxidase, subunit III
FK543_RS18160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FK543_RS18185	COG2814	Major facilitator Superfamily
FK543_RS18195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FK543_RS18200	COG0693	protein deglycase activity
FK543_RS18215	COG0142	geranyltranstransferase activity
FK543_RS18225	COG0667	Aldo Keto reductase
FK543_RS18230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FK543_RS18235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FK543_RS18250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FK543_RS18250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FK543_RS18260	COG4238	major outer membrane lipoprotein
FK543_RS18265	COG3248	Nucleoside-binding outer membrane protein
FK543_RS18270	COG1403	HNH endonuclease
FK543_RS18275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FK543_RS18280	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FK543_RS18285	COG1862	Preprotein translocase
FK543_RS18305	COG0366	Alpha amylase catalytic
FK543_RS18310	COG1113	amino acid transport
FK543_RS18315	COG1114	Component of the transport system for branched-chain amino acids
FK543_RS18320	COG5002	protein histidine kinase activity
FK543_RS18325	COG0745	RESPONSE REGULATOR receiver
FK543_RS18330	COG0420	3'-5' exonuclease activity
FK543_RS18335	COG0419	ATPase involved in DNA repair
FK543_RS18340	COG2814	Major facilitator Superfamily
FK543_RS18345	COG1940	carbohydrate kinase activity
FK543_RS18370	COG4126	flavin adenine dinucleotide binding
FK543_RS18390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FK543_RS18395	COG3706	GGDEF domain
FK543_RS18405	COG1785	Belongs to the alkaline phosphatase family
FK543_RS18415	COG1181	Belongs to the D-alanine--D-alanine ligase family
FK543_RS18435	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FK543_RS18440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FK543_RS18445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FK543_RS18450	COG3468	outer membrane autotransporter barrel domain protein
FK543_RS18455	COG0113	porphobilinogen synthase activity
FK543_RS18460	COG2175	clavaminate synthase activity
FK543_RS18465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FK543_RS18475	COG4521	taurine ABC transporter
FK543_RS18480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FK543_RS18485	COG1215	transferase activity, transferring glycosyl groups
FK543_RS18515	COG3122	Protein conserved in bacteria
FK543_RS18520	COG2814	Major facilitator Superfamily
FK543_RS18530	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS18570	COG1414	Transcriptional regulator
FK543_RS18575	COG1609	Transcriptional regulator
FK543_RS18585	COG2223	nitrite transmembrane transporter activity
FK543_RS18590	COG0110	maltose O-acetyltransferase activity
FK543_RS18595	COG2807	transmembrane transport
FK543_RS18605	COG0288	reversible hydration of carbon dioxide
FK543_RS18610	COG0583	DNA-binding transcription factor activity
FK543_RS18615	COG0402	S-adenosylhomocysteine deaminase activity
FK543_RS18620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FK543_RS18625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK543_RS18630	COG2079	MmgE PrpD family protein
FK543_RS18635	COG0372	Belongs to the citrate synthase family
FK543_RS18640	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FK543_RS18645	COG3829	transcription factor binding
FK543_RS18655	COG1280	lysine exporter protein (LysE YggA)
FK543_RS18670	COG1064	alcohol dehydrogenase
FK543_RS18680	COG1172	Belongs to the binding-protein-dependent transport system permease family
FK543_RS18685	COG1129	ABC transporter
FK543_RS18690	COG1879	ABC-type sugar transport system periplasmic component
FK543_RS18700	COG0402	S-adenosylhomocysteine deaminase activity
FK543_RS18705	COG0549	Belongs to the carbamate kinase family
FK543_RS18710	COG1304	FMN binding
FK543_RS18715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FK543_RS18725	COG0666	response to abiotic stimulus
FK543_RS18735	COG0583	DNA-binding transcription factor activity
FK543_RS18740	COG2771	luxR family
FK543_RS18740	COG2200	EAL domain
FK543_RS18750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK543_RS18775	COG0582	viral genome integration into host DNA
FK543_RS18780	COG2771	luxR family
FK543_RS18780	COG2200	EAL domain
FK543_RS18795	COG3468	outer membrane autotransporter barrel domain protein
FK543_RS18805	COG1556	Lactate utilization protein
FK543_RS18810	COG1139	Iron-sulfur cluster binding protein
FK543_RS18815	COG0247	lactate metabolic process
FK543_RS18820	COG2207	Transcriptional regulator
FK543_RS18825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK543_RS18835	COG3059	membrane
FK543_RS18840	COG0656	L-ascorbic acid biosynthetic process
FK543_RS18845	COG3708	Transcriptional regulator
FK543_RS18845	COG2207	Transcriptional regulator
FK543_RS18850	COG1388	LysM domain
FK543_RS18895	COG3188	usher protein
FK543_RS18905	COG3121	Chaperone
FK543_RS18910	COG0727	PFAM Uncharacterised protein family (UPF0153)
FK543_RS18915	COG3477	response to acidic pH
FK543_RS18965	COG0582	viral genome integration into host DNA
FK543_RS18985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FK543_RS19005	COG2195	Cleaves the N-terminal amino acid of tripeptides
FK543_RS19010	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FK543_RS19015	COG1690	Belongs to the RtcB family
FK543_RS19020	COG0454	-acetyltransferase
FK543_RS19035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FK543_RS19040	COG1191	sigma factor activity
FK543_RS19065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FK543_RS19075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FK543_RS19090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FK543_RS19115	COG4786	Flagellar basal body rod
FK543_RS19120	COG4787	bacterial-type flagellum-dependent cell motility
FK543_RS19125	COG1749	Flagellar hook protein flgE
FK543_RS19135	COG1558	bacterial-type flagellum-dependent cell motility
FK543_RS19140	COG1815	bacterial-type flagellum-dependent cell motility
FK543_RS19170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FK543_RS19190	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FK543_RS19200	COG1677	Flagellar hook-basal body complex protein FliE
FK543_RS19225	COG1987	bacterial-type flagellum assembly
FK543_RS19255	COG0791	NLP P60 protein
FK543_RS19260	COG3077	Addiction module antitoxin, RelB DinJ family
FK543_RS19265	COG3041	Addiction module toxin RelE StbE family
FK543_RS19270	COG3034	peptidoglycan biosynthetic process
FK543_RS19275	COG0121	glutamine amidotransferase
FK543_RS19285	COG1960	acyl-CoA dehydrogenase activity
FK543_RS19295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FK543_RS19345	COG3157	Type VI secretion system effector, Hcp
FK543_RS19350	COG4104	PAAR repeat-containing protein
FK543_RS19370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK543_RS19380	COG2226	methyltransferase
FK543_RS19390	COG1388	LysM domain
FK543_RS19390	COG0741	lytic transglycosylase activity
FK543_RS19395	COG2226	methyltransferase
FK543_RS19405	COG0583	DNA-binding transcription factor activity
FK543_RS19410	COG0656	L-ascorbic acid biosynthetic process
FK543_RS19445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FK543_RS19450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FK543_RS19455	COG2011	ABC-type metal ion transport system permease component
FK543_RS19460	COG1464	Belongs to the NlpA lipoprotein family
FK543_RS19470	COG1720	tRNA m6t6A37 methyltransferase activity
FK543_RS19485	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS19495	COG3015	lipoprotein NlpE involved in copper resistance
FK543_RS19500	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FK543_RS19505	COG4681	YaeQ
FK543_RS19515	COG4568	rho-dependent transcription termination
FK543_RS19525	COG0346	lactoylglutathione lyase activity
FK543_RS19530	COG1982	Orn Lys Arg decarboxylase major
FK543_RS19540	COG0587	DNA-directed DNA polymerase activity
FK543_RS19565	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FK543_RS19570	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FK543_RS19580	COG0750	zinc metalloprotease
FK543_RS19585	COG0575	Belongs to the CDS family
FK543_RS19595	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FK543_RS19620	COG0024	Methionine aminopeptidase
FK543_RS19640	COG3835	regulator
FK543_RS19645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FK543_RS19660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FK543_RS19665	COG2860	membrane
FK543_RS19690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FK543_RS19695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FK543_RS19700	COG1120	ATPase activity
FK543_RS19705	COG4774	siderophore transport
FK543_RS19710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FK543_RS19715	COG1643	Atp-dependent helicase
FK543_RS19720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FK543_RS19730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FK543_RS19740	COG0617	tRNA 3'-terminal CCA addition
FK543_RS19745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FK543_RS19750	COG3539	Fimbrial protein
FK543_RS19755	COG3121	Chaperone
FK543_RS19760	COG3188	usher protein
FK543_RS19765	COG3539	Fimbrial protein
FK543_RS19770	COG3539	Fimbrial protein
FK543_RS19775	COG3539	Fimbrial protein
FK543_RS19780	COG3539	Fimbrial protein
FK543_RS19795	COG5464	transposase or invertase
FK543_RS19805	COG0726	polysaccharide deacetylase
FK543_RS19810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS19815	COG0842	Transport permease protein
FK543_RS19820	COG1131	(ABC) transporter
FK543_RS19825	COG0288	reversible hydration of carbon dioxide
FK543_RS19830	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FK543_RS19835	COG4993	Dehydrogenase
FK543_RS19840	COG2132	Multicopper oxidase
FK543_RS19865	COG1049	propionate catabolic process, 2-methylcitrate cycle
FK543_RS19870	COG3064	Membrane
FK543_RS19875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK543_RS19880	COG0508	dehydrogenase complex catalyzes the overall conversion of
FK543_RS19885	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FK543_RS19890	COG2186	Transcriptional regulator
FK543_RS19895	COG1113	amino acid transport
FK543_RS19900	COG3725	Membrane protein required for beta-lactamase induction
FK543_RS19905	COG3023	N-Acetylmuramoyl-L-alanine amidase
FK543_RS19910	COG0157	Belongs to the NadC ModD family
FK543_RS19915	COG4969	Belongs to the N-Me-Phe pilin family
FK543_RS19920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FK543_RS19925	COG1459	type II secretion system
FK543_RS19935	COG0237	dephospho-CoA kinase activity
FK543_RS19950	COG0494	nUDIX hydrolase
FK543_RS19970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FK543_RS19975	COG0849	cell division
FK543_RS19980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FK543_RS19985	COG1181	Belongs to the D-alanine--D-alanine ligase family
FK543_RS20000	COG0772	Belongs to the SEDS family
FK543_RS20015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FK543_RS20020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FK543_RS20025	COG0768	penicillin binding
FK543_RS20030	COG3116	cell division
FK543_RS20045	COG1609	Transcriptional regulator
FK543_RS20055	COG0440	acetolactate synthase activity
FK543_RS20060	COG0028	Belongs to the TPP enzyme family
FK543_RS20065	COG0583	DNA-binding transcription factor activity
FK543_RS20080	COG0473	3-isopropylmalate dehydrogenase activity
FK543_RS20095	COG2814	Major facilitator Superfamily
FK543_RS20110	COG4143	(ABC) transporter
FK543_RS20115	COG1178	ABC-type Fe3 transport system permease component
FK543_RS20125	COG0586	Pfam SNARE associated Golgi protein
FK543_RS20130	COG4977	sequence-specific DNA binding
FK543_RS20145	COG0235	Class ii aldolase
FK543_RS20150	COG0417	DNA replication proofreading
FK543_RS20160	COG0564	pseudouridine synthase activity
FK543_RS20165	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS20170	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FK543_RS20175	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FK543_RS20180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FK543_RS20205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FK543_RS20220	COG2271	Major facilitator Superfamily
FK543_RS20230	COG0644	oxidoreductase
FK543_RS20280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FK543_RS20285	COG0505	Belongs to the CarA family
FK543_RS20305	COG1047	Peptidyl-prolyl cis-trans
FK543_RS20320	COG0196	riboflavin kinase activity
FK543_RS20350	COG0583	DNA-binding transcription factor activity
FK543_RS20380	COG4735	regulation of single-species biofilm formation
FK543_RS20385	COG1584	GPR1 FUN34 yaaH family protein
FK543_RS20390	COG0521	Mo-molybdopterin cofactor biosynthetic process
FK543_RS20400	COG1115	amino acid carrier protein
FK543_RS20410	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS20425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FK543_RS20435	COG0460	homoserine dehydrogenase
FK543_RS20435	COG0527	aspartate kinase activity
FK543_RS20445	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FK543_RS20455	COG0745	RESPONSE REGULATOR receiver
FK543_RS20460	COG4452	Inner membrane protein CreD
FK543_RS20465	COG2205	protein histidine kinase activity
FK543_RS20470	COG0745	RESPONSE REGULATOR receiver
FK543_RS20475	COG3045	CreA protein
FK543_RS20480	COG2207	Transcriptional regulator
FK543_RS20480	COG3708	Transcriptional regulator
FK543_RS20500	COG0741	lytic transglycosylase activity
FK543_RS20505	COG0488	(ABC) transporter
FK543_RS20510	COG1056	cytidyltransferase-related domain
FK543_RS20510	COG3172	ATPase kinase involved in NAD metabolism
FK543_RS20515	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FK543_RS20520	COG0560	Phosphoserine phosphatase
FK543_RS20525	COG3726	membrane protein affecting hemolysin expression
FK543_RS20555	COG1328	CTP reductase activity
FK543_RS20560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FK543_RS20565	COG0084	hydrolase, TatD family'
FK543_RS20570	COG4667	esterase of the alpha-beta hydrolase superfamily
FK543_RS20580	COG2823	Periplasmic or secreted lipoprotein
FK543_RS20590	COG1011	Hydrolase
FK543_RS20595	COG0456	acetyltransferase
FK543_RS20600	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FK543_RS20630	COG4114	ferric iron reductase
FK543_RS20635	COG2197	response regulator
FK543_RS20640	COG2197	response regulator
FK543_RS20645	COG2966	Psort location CytoplasmicMembrane, score
FK543_RS20660	COG1484	DNA-dependent DNA replication
FK543_RS20675	COG1063	alcohol dehydrogenase
FK543_RS20680	COG1802	Transcriptional regulator
FK543_RS20685	COG2271	Major facilitator Superfamily
FK543_RS20690	COG0840	transmembrane signaling receptor activity
FK543_RS20695	COG1846	Transcriptional regulator
FK543_RS20700	COG0179	Fumarylacetoacetate (FAA) hydrolase
FK543_RS20705	COG1012	belongs to the aldehyde dehydrogenase family
FK543_RS20710	COG3384	dioxygenase
FK543_RS20720	COG3971	2-oxopent-4-enoate hydratase activity
FK543_RS20740	COG2368	4-hydroxyphenylacetate
FK543_RS20745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK543_RS20750	COG1966	Carbon starvation protein
FK543_RS20755	COG2879	small protein
FK543_RS20760	COG0523	cobalamin synthesis protein
FK543_RS20785	COG0732	type I restriction modification DNA specificity domain
FK543_RS20800	COG5457	Domain of unknown function (DUF1127)
FK543_RS20805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK543_RS20820	COG2814	Major facilitator Superfamily
FK543_RS20825	COG2733	membrane
FK543_RS20830	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FK543_RS20835	COG1924	4 iron, 4 sulfur cluster binding
FK543_RS20850	COG0477	Major facilitator Superfamily
FK543_RS20860	COG3366	ferrous iron transmembrane transporter activity
FK543_RS20865	COG0700	Nucleoside recognition
FK543_RS20870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FK543_RS20875	COG0583	DNA-binding transcription factor activity
FK543_RS20895	COG2186	Transcriptional regulator
FK543_RS20900	COG0246	Mannitol dehydrogenase
FK543_RS20910	COG2610	gluconate transmembrane transporter activity
FK543_RS20915	COG3539	Fimbrial protein
FK543_RS20920	COG3539	Fimbrial protein
FK543_RS20925	COG3539	Fimbrial protein
FK543_RS20930	COG3188	usher protein
FK543_RS20940	COG3539	Fimbrial protein
FK543_RS20945	COG3539	Fimbrial protein
FK543_RS20950	COG4974	Belongs to the 'phage' integrase family
FK543_RS20955	COG0582	viral genome integration into host DNA
FK543_RS20960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FK543_RS20965	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FK543_RS20975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK543_RS20975	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FK543_RS20985	COG4372	Transposase
FK543_RS20990	COG3436	PFAM IS66 Orf2 family protein
FK543_RS21010	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FK543_RS21020	COG1363	Peptidase, m42
FK543_RS21025	COG3414	Phosphotransferase system galactitol-specific IIB component
FK543_RS21030	COG3775	system Galactitol-specific IIC component
FK543_RS21035	COG0434	BtpA family
FK543_RS21040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS21045	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FK543_RS21050	COG1349	DNA-binding transcription factor activity
FK543_RS21055	COG1414	Transcriptional regulator
FK543_RS21060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FK543_RS21065	COG0129	dihydroxy-acid dehydratase activity
FK543_RS21070	COG2610	gluconate transmembrane transporter activity
FK543_RS21075	COG2390	Transcriptional regulator
FK543_RS21210	COG3436	PFAM IS66 Orf2 family protein
FK543_RS21260	COG1595	DNA-templated transcription, initiation
FK543_RS21265	COG3712	iron ion homeostasis
FK543_RS21270	COG4772	TonB-dependent receptor
FK543_RS21275	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FK543_RS21280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FK543_RS21285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FK543_RS21290	COG1120	ATPase activity
FK543_RS21295	COG2085	NADP oxidoreductase coenzyme F420-dependent
FK543_RS21315	COG1064	alcohol dehydrogenase
FK543_RS21320	COG0433	COG0433 Predicted ATPase
FK543_RS21325	COG0795	lipopolysaccharide-transporting ATPase activity
FK543_RS21330	COG0795	lipopolysaccharide-transporting ATPase activity
FK543_RS21340	COG2927	DNA polymerase III (CHI subunit)
FK543_RS21345	COG0525	valine-tRNA ligase activity
FK543_RS21350	COG4269	membrane
FK543_RS21355	COG0456	acetyltransferase
FK543_RS21360	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FK543_RS21375	COG2731	YhcH YjgK YiaL family protein
FK543_RS21385	COG1028	Short-chain dehydrogenase reductase Sdr
FK543_RS21390	COG0251	oxidation-reduction process
FK543_RS21410	COG0251	oxidation-reduction process
FK543_RS21420	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS21425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FK543_RS21435	COG1609	Transcriptional regulator
FK543_RS21440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS21440	COG1263	PTS System
FK543_RS21445	COG0366	Alpha amylase catalytic
FK543_RS21450	COG1328	CTP reductase activity
FK543_RS21455	COG0602	queuosine metabolic process
FK543_RS21460	COG3783	Cytochrome b(562)
FK543_RS21465	COG0312	modulator of DNA gyrase
FK543_RS21475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FK543_RS21485	COG1172	Belongs to the binding-protein-dependent transport system permease family
FK543_RS21490	COG1172	Belongs to the binding-protein-dependent transport system permease family
FK543_RS21495	COG1129	ABC transporter
FK543_RS21500	COG1879	ABC-type sugar transport system periplasmic component
FK543_RS21505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FK543_RS21510	COG2337	Toxic component of a toxin-antitoxin (TA) module
FK543_RS21515	COG2336	PFAM SpoVT AbrB
FK543_RS21520	COG2105	PFAM AIG2 family protein
FK543_RS21525	COG2911	Protein conserved in bacteria
FK543_RS21530	COG0729	surface antigen
FK543_RS21540	COG3547	Transposase (IS116 IS110 IS902 family)
FK543_RS21550	COG1253	flavin adenine dinucleotide binding
FK543_RS21560	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FK543_RS21565	COG1218	3'(2'),5'-bisphosphate nucleotidase
FK543_RS21570	COG0737	Belongs to the 5'-nucleotidase family
FK543_RS21575	COG1733	regulation of RNA biosynthetic process
FK543_RS21580	COG0702	epimerase
FK543_RS21585	COG0697	spore germination
FK543_RS21595	COG1113	amino acid transport
FK543_RS21600	COG0545	Peptidyl-prolyl cis-trans isomerase
FK543_RS21610	COG3061	Opacity-associated protein A
FK543_RS21615	COG1309	transcriptional regulator
FK543_RS21630	COG1024	Enoyl-CoA hydratase
FK543_RS21635	COG4670	ketone body catabolic process
FK543_RS21640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FK543_RS21645	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FK543_RS21655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FK543_RS21665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FK543_RS21710	COG3037	sugar-specific permease SgaT UlaA
FK543_RS21725	COG1073	alpha beta
FK543_RS21730	COG3650	response to hydrogen peroxide
FK543_RS21740	COG1960	acyl-CoA dehydrogenase activity
FK543_RS21745	COG0754	glutathionylspermidine amidase activity
FK543_RS21750	COG5463	Belongs to the UPF0441 family
FK543_RS21755	COG3766	membrane
FK543_RS21765	COG1842	Phage shock protein A
FK543_RS21770	COG3789	protein conserved in bacteria
FK543_RS21775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FK543_RS21780	COG0557	exoribonuclease II activity
FK543_RS21795	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FK543_RS21800	COG0330	HflC and HflK could
FK543_RS21805	COG0330	HflC and HflK could
FK543_RS21810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FK543_RS21830	COG0860	N-Acetylmuramoyl-L-alanine amidase
FK543_RS21835	COG0802	atpase or kinase
FK543_RS21840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FK543_RS21840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FK543_RS21845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FK543_RS21885	COG3264	Mechanosensitive ion channel
FK543_RS21885	COG1511	domain protein
FK543_RS21900	COG0531	amino acid
FK543_RS21910	COG1053	succinate dehydrogenase
FK543_RS21915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FK543_RS21930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FK543_RS21935	COG3040	lipid binding
FK543_RS21940	COG2076	Multidrug Resistance protein
FK543_RS21945	COG5510	response to toxic substance
FK543_RS21950	COG5510	response to toxic substance
FK543_RS21960	COG1509	lysine 2,3-aminomutase activity
FK543_RS21985	COG0531	amino acid
FK543_RS21990	COG3030	protein affecting phage T7 exclusion by the F plasmid
FK543_RS21995	COG1027	Aspartate ammonia-lyase
FK543_RS22000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FK543_RS22015	COG1309	transcriptional regulator
FK543_RS22025	COG3710	Transcriptional regulator
FK543_RS22035	COG0531	amino acid
FK543_RS22040	COG1982	Orn Lys Arg decarboxylase major
FK543_RS22045	COG3104	oligopeptide transport
FK543_RS22050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FK543_RS22065	COG2388	GCN5-related N-acetyl-transferase
FK543_RS22070	COG3592	Divergent 4Fe-4S mono-cluster
FK543_RS22075	COG3290	protein histidine kinase activity
FK543_RS22080	COG4565	transcriptional regulatory protein
FK543_RS22085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FK543_RS22090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FK543_RS22090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FK543_RS22095	COG3647	Membrane
FK543_RS22105	COG2211	Major facilitator Superfamily
FK543_RS22110	COG1486	melibiose metabolic process
FK543_RS22115	COG2169	Transcriptional regulator
FK543_RS22120	COG1982	Orn Lys Arg decarboxylase major
FK543_RS22125	COG2207	Transcriptional regulator
FK543_RS22130	COG0531	amino acid
FK543_RS22135	COG2194	sulfuric ester hydrolase activity
FK543_RS22140	COG0745	RESPONSE REGULATOR receiver
FK543_RS22145	COG0642	Histidine kinase
FK543_RS22155	COG0477	Major facilitator Superfamily
FK543_RS22170	COG2824	Alkylphosphonate utilization operon protein PhnA
FK543_RS22175	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FK543_RS22185	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FK543_RS22190	COG3639	organic phosphonate transmembrane transporter activity
FK543_RS22195	COG2188	Transcriptional regulator
FK543_RS22200	COG3624	Phosphonate C-P lyase system protein PhnG
FK543_RS22205	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FK543_RS22210	COG3626	phosphonate metabolism
FK543_RS22215	COG3627	carbon phosphorus lyase activity
FK543_RS22220	COG4107	phosphonate C-P lyase system protein PhnK
FK543_RS22225	COG4778	phosphonate C-P lyase system protein PhnL
FK543_RS22230	COG3454	Phosphonate metabolism
FK543_RS22235	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FK543_RS22240	COG0456	acetyltransferase
FK543_RS22245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FK543_RS22255	COG0698	ribose 5-phosphate isomerase
FK543_RS22260	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FK543_RS22270	COG1566	PFAM secretion protein HlyD family protein
FK543_RS22275	COG1289	transmembrane transporter activity
FK543_RS22290	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FK543_RS22295	COG1301	dicarboxylic acid transport
FK543_RS22300	COG4235	cytochrome complex assembly
FK543_RS22305	COG3088	subunit of a heme lyase
FK543_RS22315	COG3301	Polysulphide reductase, NrfD
FK543_RS22320	COG0437	4 iron, 4 sulfur cluster binding
FK543_RS22325	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FK543_RS22335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK543_RS22340	COG3162	membrane
FK543_RS22350	COG1357	PFAM Pentapeptide repeats (8 copies)
FK543_RS22355	COG0025	NhaP-type Na H and K H
FK543_RS22360	COG2252	PERMEase
FK543_RS22365	COG0789	Transcriptional regulator
FK543_RS22370	COG2207	Transcriptional regulator
FK543_RS22375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FK543_RS22385	COG0629	single-stranded DNA binding
FK543_RS22390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FK543_RS22395	COG2315	Protein conserved in bacteria
FK543_RS22400	COG0432	Pfam Uncharacterised protein family UPF0047
FK543_RS22405	COG3700	Belongs to the class B bacterial acid phosphatase family
FK543_RS22420	COG1448	Aminotransferase
FK543_RS22425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FK543_RS22430	COG0305	Participates in initiation and elongation during chromosome replication
FK543_RS22435	COG0604	alcohol dehydrogenase
FK543_RS22445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FK543_RS22455	COG0735	belongs to the Fur family
FK543_RS22460	COG3237	CsbD-like
FK543_RS22465	COG0534	Mate efflux family protein
FK543_RS22475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FK543_RS22510	COG3842	ATPase activity
FK543_RS22515	COG2182	Extracellular solute-binding protein
FK543_RS22520	COG1175	transmembrane transport
FK543_RS22525	COG3833	ABC-type maltose transport systems, permease component
FK543_RS22530	COG0477	Major facilitator Superfamily
FK543_RS22530	COG2814	Major facilitator Superfamily
FK543_RS22545	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK543_RS22570	COG0527	aspartate kinase activity
FK543_RS22575	COG0542	response to heat
FK543_RS22580	COG3541	Predicted nucleotidyltransferase
FK543_RS22595	COG1187	pseudouridine synthase activity
FK543_RS22605	COG1283	sodium-dependent phosphate transmembrane transporter activity
FK543_RS22610	COG0646	methionine synthase
FK543_RS22610	COG1410	methionine synthase
FK543_RS22615	COG1414	Transcriptional regulator
FK543_RS22630	COG2224	Isocitrate lyase
FK543_RS22635	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FK543_RS22645	COG0456	acetyltransferase
FK543_RS22675	COG0151	Belongs to the GarS family
FK543_RS22680	COG2204	response regulator
FK543_RS22685	COG4191	Histidine kinase
FK543_RS22690	COG3678	ATP-independent chaperone mediated protein folding
FK543_RS22705	COG3068	Protein conserved in bacteria
FK543_RS22740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FK543_RS22745	COG2104	thiamine diphosphate biosynthetic process
FK543_RS22755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FK543_RS22795	COG0250	Participates in transcription elongation, termination and antitermination
FK543_RS22800	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FK543_RS22835	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FK543_RS22835	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FK543_RS22890	COG1309	transcriptional regulator
FK543_RS22900	COG0583	DNA-binding transcription factor activity
FK543_RS22905	COG2271	Major facilitator Superfamily
FK543_RS22910	COG4948	Mandelate Racemase Muconate Lactonizing
FK543_RS22930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FK543_RS22945	COG2194	sulfuric ester hydrolase activity
FK543_RS22950	COG2207	Transcriptional regulator
FK543_RS22955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK543_RS22960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FK543_RS22965	COG1882	Formate acetyltransferase
FK543_RS22970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK543_RS22975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK543_RS22980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FK543_RS22980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS22980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS22985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FK543_RS22990	COG0371	Dehydrogenase
FK543_RS22995	COG3738	Protein conserved in bacteria
FK543_RS23000	COG0697	spore germination
FK543_RS23010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FK543_RS23015	COG0527	aspartate kinase activity
FK543_RS23015	COG0460	homoserine dehydrogenase
FK543_RS23020	COG0626	cystathionine gamma-synthase activity
FK543_RS23030	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FK543_RS23040	COG3209	COG3209 Rhs family protein
FK543_RS23050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FK543_RS23055	COG1609	Transcriptional regulator
FK543_RS23060	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FK543_RS23075	COG1575	Belongs to the MenA family. Type 1 subfamily
FK543_RS23090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FK543_RS23100	COG1494	fructose-1,6-bisphosphatase
FK543_RS23110	COG0589	response to stress
FK543_RS23115	COG3691	Protein conserved in bacteria
FK543_RS23120	COG3152	Membrane
FK543_RS23140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FK543_RS23155	COG3678	ATP-independent chaperone mediated protein folding
FK543_RS23160	COG0745	RESPONSE REGULATOR receiver
FK543_RS23165	COG2205	protein histidine kinase activity
FK543_RS23170	COG2258	MOSC domain
FK543_RS23180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FK543_RS23220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS23225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK543_RS23225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK543_RS23230	COG1363	Peptidase, m42
FK543_RS23235	COG3711	transcriptional antiterminator
FK543_RS23235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK543_RS23255	COG0437	4 iron, 4 sulfur cluster binding
FK543_RS23260	COG2864	formate dehydrogenase
FK543_RS23270	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK543_RS23275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK543_RS23285	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FK543_RS23295	COG0456	acetyltransferase
FK543_RS23310	COG1011	Hydrolase
FK543_RS23320	COG0477	Major facilitator Superfamily
FK543_RS23330	COG1063	alcohol dehydrogenase
FK543_RS23335	COG3684	Belongs to the aldolase LacD family
FK543_RS23340	COG2084	Dehydrogenase
FK543_RS23345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FK543_RS23350	COG1349	DNA-binding transcription factor activity
FK543_RS23355	COG2271	Major facilitator Superfamily
FK543_RS23360	COG1082	Xylose isomerase domain protein TIM barrel
FK543_RS23365	COG2188	Transcriptional regulator
FK543_RS23370	COG1217	gtp-binding protein TYPA
FK543_RS23375	COG0174	glutamine synthetase
FK543_RS23380	COG3852	Histidine kinase
FK543_RS23385	COG2204	response regulator
FK543_RS23395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FK543_RS23410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FK543_RS23410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FK543_RS23420	COG0204	Acyl-transferase
FK543_RS23425	COG5339	Protein conserved in bacteria
FK543_RS23430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK543_RS23435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FK543_RS23440	COG3084	Protein conserved in bacteria
FK543_RS23445	COG0746	molybdenum cofactor guanylyltransferase activity
FK543_RS23450	COG1763	Mo-molybdopterin cofactor biosynthetic process
FK543_RS23480	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FK543_RS23485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FK543_RS23490	COG1739	Uncharacterized protein family UPF0029
FK543_RS23510	COG0543	2 iron, 2 sulfur cluster binding
FK543_RS23515	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FK543_RS23520	COG0250	Participates in transcription elongation, termination and antitermination
FK543_RS23530	COG0805	protein transport
FK543_RS23535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FK543_RS23540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FK543_RS23550	COG3165	ubiquinone biosynthetic process from chorismate
FK543_RS23560	COG1322	Protein conserved in bacteria
FK543_RS23565	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FK543_RS23570	COG0412	Dienelactone hydrolase
FK543_RS23580	COG0583	DNA-binding transcription factor activity
FK543_RS23585	COG0697	spore germination
FK543_RS23590	COG0561	phosphatase activity
FK543_RS23595	COG2267	carboxylic ester hydrolase activity
FK543_RS23600	COG1280	lysine exporter protein (LysE YggA)
FK543_RS23605	COG1280	lysine exporter protein (LysE YggA)
FK543_RS23610	COG0514	ATP-dependent DNA helicase (RecQ)
FK543_RS23615	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FK543_RS23620	COG2050	protein possibly involved in aromatic compounds catabolism
FK543_RS23625	COG2962	Rard protein
FK543_RS23655	COG0598	Magnesium transport protein CorA
FK543_RS23660	COG3698	Phosphodiester glycosidase
FK543_RS23665	COG0210	DNA helicase
FK543_RS23670	COG1011	Hydrolase
FK543_RS23680	COG3159	Protein conserved in bacteria
FK543_RS23690	COG5567	small periplasmic lipoprotein
FK543_RS23700	COG3072	Adenylate cyclase
FK543_RS23710	COG1587	Uroporphyrinogen-III synthase
FK543_RS23715	COG2959	enzyme of heme biosynthesis
FK543_RS23720	COG3071	HemY protein
FK543_RS23725	COG0641	radical SAM
FK543_RS23750	COG1113	amino acid transport
FK543_RS23770	COG2244	polysaccharide biosynthetic process
FK543_RS23775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FK543_RS23780	COG0456	acetyltransferase
FK543_RS23785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FK543_RS23790	COG1088	dTDP-glucose 4,6-dehydratase activity
FK543_RS23795	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FK543_RS23800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FK543_RS23805	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FK543_RS23810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FK543_RS23815	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FK543_RS23825	COG3118	belongs to the thioredoxin family
FK543_RS23840	COG0210	DNA helicase
FK543_RS23845	COG3692	DNA binding
FK543_RS23850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FK543_RS23860	COG0583	DNA-binding transcription factor activity
FK543_RS23865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FK543_RS23875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FK543_RS23880	COG3978	acetolactate synthase activity
FK543_RS23910	COG3085	chromosome segregation
FK543_RS23950	COG2186	Transcriptional regulator
FK543_RS23955	COG0477	Major facilitator Superfamily
FK543_RS23960	COG1609	Transcriptional regulator
FK543_RS23965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FK543_RS23970	COG1879	ABC-type sugar transport system periplasmic component
FK543_RS23975	COG1172	Belongs to the binding-protein-dependent transport system permease family
FK543_RS23980	COG1129	ABC transporter
FK543_RS24010	COG1522	sequence-specific DNA binding
FK543_RS24015	COG0716	FMN binding
FK543_RS24030	COG3312	ion transport
FK543_RS24085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FK543_RS24090	COG3539	Fimbrial protein
FK543_RS24110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FK543_RS24115	COG0573	inorganic phosphate transmembrane transporter activity
FK543_RS24120	COG0581	inorganic phosphate transmembrane transporter activity
FK543_RS24125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FK543_RS24130	COG0704	Plays a role in the regulation of phosphate uptake
FK543_RS24135	COG3711	transcriptional antiterminator
FK543_RS24140	COG2190	(PTS) system
FK543_RS24140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FK543_RS24140	COG1263	PTS System
FK543_RS24145	COG2723	6-phospho-beta-galactosidase activity
FK543_RS24155	COG2382	esterase
FK543_RS24160	COG0363	glucosamine-6-phosphate deaminase activity
FK543_RS24165	COG3196	Protein conserved in bacteria
FK543_RS24175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FK543_RS24180	COG2252	PERMEase
FK543_RS24185	COG0431	NADPH-dependent FMN reductase
FK543_RS24190	COG2091	lysine biosynthetic process via aminoadipic acid