locus-tag	class	description
F3052_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F3052_RS00010	COG0592	DNA-directed DNA polymerase activity
F3052_RS00020	COG0187	DNA topoisomerase II activity
F3052_RS00025	COG3753	Protein conserved in bacteria
F3052_RS00030	COG0561	phosphatase activity
F3052_RS00040	COG2186	Transcriptional regulator
F3052_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
F3052_RS00050	COG0800	Aldolase
F3052_RS00060	COG2271	Major facilitator Superfamily
F3052_RS00065	COG0644	oxidoreductase
F3052_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
F3052_RS00075	COG5645	(Lipo)protein
F3052_RS00095	COG2188	Transcriptional regulator
F3052_RS00125	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3052_RS00130	COG3119	arylsulfatase activity
F3052_RS00140	COG2149	membrane
F3052_RS00150	COG0641	radical SAM
F3052_RS00155	COG2814	Major facilitator Superfamily
F3052_RS00170	COG0028	Belongs to the TPP enzyme family
F3052_RS00175	COG0440	acetolactate synthase activity
F3052_RS00180	COG2197	response regulator
F3052_RS00185	COG3851	Histidine kinase
F3052_RS00190	COG2271	Major facilitator Superfamily
F3052_RS00195	COG2271	Major facilitator Superfamily
F3052_RS00205	COG2252	PERMEase
F3052_RS00225	COG1464	Belongs to the NlpA lipoprotein family
F3052_RS00230	COG0697	spore germination
F3052_RS00235	COG2814	Major facilitator Superfamily
F3052_RS00250	COG1501	Belongs to the glycosyl hydrolase 31 family
F3052_RS00255	COG2982	Protein involved in outer membrane biogenesis
F3052_RS00260	COG2233	PERMEase
F3052_RS00265	COG0786	glutamate:sodium symporter activity
F3052_RS00270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F3052_RS00275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3052_RS00280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F3052_RS00290	COG0194	GDP metabolic process
F3052_RS00300	COG2860	membrane
F3052_RS00305	COG3645	SOS response
F3052_RS00310	COG1561	YicC-like family, N-terminal region
F3052_RS00330	COG0756	dUTP diphosphatase activity
F3052_RS00335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3052_RS00365	COG1519	Transferase
F3052_RS00370	COG0859	PFAM glycosyl transferase family 9
F3052_RS00375	COG0438	transferase activity, transferring glycosyl groups
F3052_RS00380	COG0515	serine threonine protein kinase
F3052_RS00385	COG4641	Protein conserved in bacteria
F3052_RS00385	COG0438	transferase activity, transferring glycosyl groups
F3052_RS00390	COG0438	transferase activity, transferring glycosyl groups
F3052_RS00395	COG1442	glycosyl transferase family 8
F3052_RS00400	COG1442	glycosyl transferase family 8
F3052_RS00405	COG3642	lipopolysaccharide core region biosynthetic process
F3052_RS00415	COG0859	PFAM glycosyl transferase family 9
F3052_RS00420	COG3307	-O-antigen
F3052_RS00425	COG0859	PFAM glycosyl transferase family 9
F3052_RS00430	COG0859	PFAM glycosyl transferase family 9
F3052_RS00445	COG0156	8-amino-7-oxononanoate synthase activity
F3052_RS00455	COG1216	Glycosyl transferase, family 2
F3052_RS00460	COG2861	carbohydrate metabolic process
F3052_RS00465	COG4942	peptidase
F3052_RS00470	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F3052_RS00475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3052_RS00480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3052_RS00495	COG1045	serine acetyltransferase
F3052_RS00500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3052_RS00510	COG2186	Transcriptional regulator
F3052_RS00515	COG1620	l-lactate permease
F3052_RS00530	COG3722	fumarate hydratase activity
F3052_RS00540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS00540	COG2213	PTS system mannitol-specific
F3052_RS00565	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F3052_RS00575	COG1413	lyase activity
F3052_RS00580	COG3209	COG3209 Rhs family protein
F3052_RS00585	COG0625	glutathione transferase activity
F3052_RS00595	COG3276	selenocysteine insertion sequence binding
F3052_RS00600	COG1454	alcohol dehydrogenase
F3052_RS00605	COG1012	belongs to the aldehyde dehydrogenase family
F3052_RS00620	COG1566	PFAM secretion protein HlyD family protein
F3052_RS00625	COG0583	DNA-binding transcription factor activity
F3052_RS00630	COG3713	MltA-interacting MipA family protein
F3052_RS00640	COG0235	Class ii aldolase
F3052_RS00645	COG3623	hexulose-6-phosphate isomerase
F3052_RS00650	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
F3052_RS00655	COG1070	Carbohydrate kinase
F3052_RS00660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3052_RS00665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3052_RS00670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F3052_RS00675	COG2731	YhcH YjgK YiaL family protein
F3052_RS00685	COG1414	Transcriptional regulator
F3052_RS00690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS00695	COG3977	Valine--pyruvate aminotransferase
F3052_RS00700	COG0366	Alpha amylase catalytic
F3052_RS00705	COG2992	FlgJ-related protein
F3052_RS00710	COG2207	Transcriptional regulator
F3052_RS00710	COG1609	Transcriptional regulator
F3052_RS00715	COG4214	carbohydrate transport
F3052_RS00720	COG1129	ABC transporter
F3052_RS00725	COG4213	ABC transporter substrate-binding protein
F3052_RS00735	COG1070	Carbohydrate kinase
F3052_RS00740	COG4682	membrane
F3052_RS00745	COG4682	membrane
F3052_RS00750	COG3274	enterobacterial common antigen metabolic process
F3052_RS00780	COG1278	Cold shock
F3052_RS00785	COG2944	sequence-specific DNA binding
F3052_RS00800	COG2885	chlorophyll binding
F3052_RS00805	COG0243	molybdopterin cofactor binding
F3052_RS00810	COG0456	acetyltransferase
F3052_RS00815	COG2818	Glycosylase
F3052_RS00820	COG5571	outer membrane autotransporter
F3052_RS00825	COG2223	nitrite transmembrane transporter activity
F3052_RS00830	COG2194	sulfuric ester hydrolase activity
F3052_RS00845	COG0747	negative chemotaxis
F3052_RS00850	COG0601	transmembrane transport
F3052_RS00855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3052_RS00860	COG0444	Belongs to the ABC transporter superfamily
F3052_RS00865	COG4608	Belongs to the ABC transporter superfamily
F3052_RS00870	COG0814	amino acid
F3052_RS00880	COG2194	sulfuric ester hydrolase activity
F3052_RS00905	COG1215	transferase activity, transferring glycosyl groups
F3052_RS00910	COG1215	transferase activity, transferring glycosyl groups
F3052_RS00915	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F3052_RS00920	COG0457	Tetratricopeptide repeat
F3052_RS00920	COG3118	belongs to the thioredoxin family
F3052_RS00925	COG2200	EAL domain
F3052_RS00925	COG2199	diguanylate cyclase activity
F3052_RS00935	COG0612	Peptidase, M16
F3052_RS00940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3052_RS00945	COG2200	EAL domain
F3052_RS00950	COG2982	Protein involved in outer membrane biogenesis
F3052_RS00955	COG0477	Major facilitator Superfamily
F3052_RS00960	COG1295	ribonuclease BN
F3052_RS00965	COG0583	DNA-binding transcription factor activity
F3052_RS00970	COG2197	response regulator
F3052_RS00980	COG1858	cytochrome C peroxidase
F3052_RS00985	COG0076	glutamate decarboxylase activity
F3052_RS00990	COG2207	Transcriptional regulator
F3052_RS00995	COG2207	Transcriptional regulator
F3052_RS01000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3052_RS01005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3052_RS01015	COG2771	luxR family
F3052_RS01020	COG3247	response to pH
F3052_RS01035	COG1285	pathogenesis
F3052_RS01040	COG2197	response regulator
F3052_RS01045	COG3065	identical protein binding
F3052_RS01055	COG1393	Belongs to the ArsC family
F3052_RS01060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F3052_RS01065	COG0640	Transcriptional regulator
F3052_RS01075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3052_RS01080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F3052_RS01085	COG0339	signal peptide processing
F3052_RS01095	COG3104	oligopeptide transport
F3052_RS01100	COG0589	response to stress
F3052_RS01110	COG0306	phosphate transporter
F3052_RS01115	COG2081	HI0933 family
F3052_RS01135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3052_RS01140	COG0842	Transport permease protein
F3052_RS01140	COG1129	ABC transporter
F3052_RS01145	COG0842	Transport permease protein
F3052_RS01150	COG5433	transposase activity
F3052_RS01155	COG1413	lyase activity
F3052_RS01165	COG3209	COG3209 Rhs family protein
F3052_RS01175	COG1124	(ABC) transporter
F3052_RS01180	COG0444	Belongs to the ABC transporter superfamily
F3052_RS01185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3052_RS01190	COG0601	transmembrane transport
F3052_RS01195	COG0747	negative chemotaxis
F3052_RS01200	COG2091	lysine biosynthetic process via aminoadipic acid
F3052_RS01205	COG0628	permease
F3052_RS01210	COG0477	Major facilitator Superfamily
F3052_RS01220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F3052_RS01230	COG2217	Heavy metal translocating P-type atpase
F3052_RS01235	COG3714	YhhN family
F3052_RS01245	COG3776	membrane
F3052_RS01250	COG0742	ribosomal rna small subunit methyltransferase
F3052_RS01255	COG0552	protein localization to endoplasmic reticulum
F3052_RS01260	COG2884	Cell division ATP-binding protein ftsE
F3052_RS01265	COG2177	Part of the ABC transporter FtsEX involved in
F3052_RS01270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3052_RS01275	COG0683	leucine binding
F3052_RS01280	COG0456	acetyltransferase
F3052_RS01285	COG0683	leucine binding
F3052_RS01290	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3052_RS01295	COG4177	L-phenylalanine transmembrane transporter activity
F3052_RS01300	COG0411	ABC transporter
F3052_RS01305	COG0410	ABC transporter
F3052_RS01310	COG1653	transport
F3052_RS01315	COG1175	transmembrane transport
F3052_RS01320	COG0395	ABC-type sugar transport system, permease component
F3052_RS01325	COG3842	ATPase activity
F3052_RS01330	COG0584	glycerophosphoryl diester phosphodiesterase
F3052_RS01340	COG0405	Gamma-glutamyltransferase
F3052_RS01360	COG3157	Type VI secretion system effector, Hcp
F3052_RS01365	COG1247	-acetyltransferase
F3052_RS01370	COG0673	inositol 2-dehydrogenase activity
F3052_RS01375	COG1741	Belongs to the pirin family
F3052_RS01380	COG1609	Transcriptional regulator
F3052_RS01385	COG3265	gluconokinase activity
F3052_RS01390	COG2610	gluconate transmembrane transporter activity
F3052_RS01395	COG2095	MarC family integral membrane protein
F3052_RS01400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3052_RS01425	COG0058	SHG alpha-glucan phosphorylase activity
F3052_RS01435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3052_RS01450	COG1349	DNA-binding transcription factor activity
F3052_RS01455	COG4650	regulator
F3052_RS01460	COG1690	Belongs to the RtcB family
F3052_RS01475	COG0058	SHG alpha-glucan phosphorylase activity
F3052_RS01480	COG1640	4-alpha-glucanotransferase
F3052_RS01485	COG2610	gluconate transmembrane transporter activity
F3052_RS01495	COG1040	competence protein
F3052_RS01505	COG5464	transposase or invertase
F3052_RS01515	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
F3052_RS01520	COG1918	ferrous iron import across plasma membrane
F3052_RS01525	COG2183	response to ionizing radiation
F3052_RS01530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3052_RS01550	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F3052_RS01560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F3052_RS01565	COG1011	Hydrolase
F3052_RS01575	COG0494	nUDIX hydrolase
F3052_RS01580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3052_RS01585	COG4972	Pilus assembly protein
F3052_RS01590	COG3166	PFAM Fimbrial assembly family protein
F3052_RS01605	COG4796	Type ii and iii secretion system protein
F3052_RS01620	COG3266	domain, Protein
F3052_RS01625	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F3052_RS01630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3052_RS01635	COG0546	phosphoglycolate phosphatase activity
F3052_RS01640	COG0180	Tryptophanyl-tRNA synthetase
F3052_RS01645	COG2188	Transcriptional regulator
F3052_RS01655	COG3457	Alanine racemase
F3052_RS01660	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F3052_RS01665	COG1735	metal-dependent hydrolase with the TIM-barrel fold
F3052_RS01680	COG0626	cystathionine gamma-synthase activity
F3052_RS01685	COG2188	Transcriptional regulator
F3052_RS01690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3052_RS01695	COG1082	Xylose isomerase domain protein TIM barrel
F3052_RS01700	COG2222	sugar isomerase
F3052_RS01705	COG0531	amino acid
F3052_RS01720	COG2116	formate transmembrane transporter activity
F3052_RS01725	COG2146	nitrite reductase [NAD(P)H] activity
F3052_RS01730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3052_RS01740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F3052_RS01750	COG2184	nucleotidyltransferase activity
F3052_RS01755	COG0512	Glutamine amidotransferase of anthranilate synthase
F3052_RS01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3052_RS01765	COG1289	transmembrane transporter activity
F3052_RS01770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3052_RS01775	COG1765	OsmC-like protein
F3052_RS01780	COG3954	Phosphoribulokinase
F3052_RS01790	COG0429	hydrolase of the alpha beta-hydrolase fold
F3052_RS01795	COG0488	(ABC) transporter
F3052_RS01810	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F3052_RS01815	COG1047	Peptidyl-prolyl cis-trans
F3052_RS01825	COG0545	Peptidyl-prolyl cis-trans isomerase
F3052_RS01830	COG2964	Protein conserved in bacteria
F3052_RS01870	COG3979	chitinase
F3052_RS01875	COG2906	2 iron, 2 sulfur cluster binding
F3052_RS01880	COG2193	ferroxidase activity
F3052_RS01885	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
F3052_RS01890	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
F3052_RS01895	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
F3052_RS01905	COG4795	General secretion pathway protein
F3052_RS01910	COG2165	general secretion pathway protein
F3052_RS01915	COG2165	general secretion pathway protein
F3052_RS01920	COG2165	general secretion pathway protein
F3052_RS01925	COG1459	type II secretion system
F3052_RS01930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3052_RS01935	COG1450	Type ii and iii secretion system protein
F3052_RS01940	COG3031	protein transport across the cell outer membrane
F3052_RS01945	COG3267	Type II secretory pathway component ExeA
F3052_RS01945	COG3409	Peptidoglycan-binding domain 1 protein
F3052_RS01970	COG0089	rRNA binding
F3052_RS02060	COG0201	protein transport
F3052_RS02100	COG0789	Transcriptional regulator
F3052_RS02105	COG3036	rescue of stalled ribosome
F3052_RS02115	COG0569	domain protein
F3052_RS02135	COG0758	DNA mediated transformation
F3052_RS02145	COG0551	DNA topoisomerase type I activity
F3052_RS02165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F3052_RS02205	COG1126	abc transporter atp-binding protein
F3052_RS02210	COG0765	amino acid transport
F3052_RS02215	COG4597	amino acid ABC transporter
F3052_RS02220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3052_RS02230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3052_RS02235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3052_RS02240	COG1309	transcriptional regulator
F3052_RS02250	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F3052_RS02260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3052_RS02270	COG4145	pantothenate transmembrane transporter activity
F3052_RS02275	COG3924	membrane
F3052_RS02280	COG0439	Biotin carboxylase
F3052_RS02285	COG0511	ligase activity, forming carbon-carbon bonds
F3052_RS02290	COG0604	alcohol dehydrogenase
F3052_RS02295	COG2200	EAL domain
F3052_RS02295	COG2199	diguanylate cyclase activity
F3052_RS02300	COG1077	Cell shape determining protein MreB Mrl
F3052_RS02305	COG1792	Involved in formation and maintenance of cell shape
F3052_RS02310	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F3052_RS02315	COG0424	maF-like protein
F3052_RS02320	COG1530	ribonuclease E activity
F3052_RS02325	COG3164	Protein of unknown function
F3052_RS02330	COG0312	modulator of DNA gyrase
F3052_RS02335	COG0583	DNA-binding transcription factor activity
F3052_RS02355	COG2732	(Barnase) inhibitor
F3052_RS02375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3052_RS02380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3052_RS02385	COG3105	Protein conserved in bacteria
F3052_RS02390	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F3052_RS02405	COG0625	glutathione transferase activity
F3052_RS02410	COG2969	positive regulation of protein catabolic process
F3052_RS02415	COG3069	C4-dicarboxylate transmembrane transporter activity
F3052_RS02445	COG2731	YhcH YjgK YiaL family protein
F3052_RS02450	COG4804	nuclease activity
F3052_RS02480	COG3188	usher protein
F3052_RS02485	COG3121	Chaperone
F3052_RS02490	COG3539	Fimbrial protein
F3052_RS02495	COG0493	'glutamate synthase
F3052_RS02500	COG0070	glutamate synthase
F3052_RS02500	COG0069	glutamate synthase activity
F3052_RS02500	COG0067	glutamate synthase
F3052_RS02505	COG1242	4 iron, 4 sulfur cluster binding
F3052_RS02510	COG0784	Response regulator, receiver
F3052_RS02510	COG2198	Histidine kinase
F3052_RS02510	COG5002	protein histidine kinase activity
F3052_RS02515	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F3052_RS02525	COG0515	serine threonine protein kinase
F3052_RS02530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS02545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3052_RS02550	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F3052_RS02555	COG1137	ATPase activity
F3052_RS02560	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F3052_RS02565	COG3117	lipopolysaccharide transmembrane transporter activity
F3052_RS02570	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F3052_RS02575	COG0517	IMP dehydrogenase activity
F3052_RS02575	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F3052_RS02580	COG0530	calcium, potassium:sodium antiporter activity
F3052_RS02585	COG1127	ABC transporter
F3052_RS02590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F3052_RS02595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F3052_RS02600	COG2854	intermembrane phospholipid transfer
F3052_RS02605	COG3113	response to antibiotic
F3052_RS02610	COG5007	Belongs to the BolA IbaG family
F3052_RS02620	COG3423	Transcriptional regulator
F3052_RS02625	COG0142	geranyltranstransferase activity
F3052_RS02640	COG0697	spore germination
F3052_RS02650	COG2027	D-alanyl-D-alanine carboxypeptidase
F3052_RS02655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3052_RS02660	COG1534	Rna-binding protein
F3052_RS02670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3052_RS02675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F3052_RS02685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3052_RS02695	COG2194	sulfuric ester hydrolase activity
F3052_RS02715	COG0195	Participates in both transcription termination and antitermination
F3052_RS02755	COG0513	Belongs to the DEAD box helicase family
F3052_RS02760	COG0814	amino acid
F3052_RS02765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3052_RS02770	COG0826	peptidase U32
F3052_RS02775	COG0826	peptidase U32
F3052_RS02780	COG3154	lipid carrier protein
F3052_RS02785	COG3153	acetyltransferase
F3052_RS02800	COG0693	protein deglycase activity
F3052_RS02805	COG0702	epimerase
F3052_RS02810	COG0701	Predicted permease
F3052_RS02815	COG2823	Periplasmic or secreted lipoprotein
F3052_RS02830	COG3107	peptidoglycan biosynthetic process
F3052_RS02835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F3052_RS02840	COG3539	Fimbrial protein
F3052_RS02860	COG3121	Chaperone
F3052_RS02865	COG3539	Fimbrial protein
F3052_RS02870	COG0363	glucosamine-6-phosphate deaminase activity
F3052_RS02875	COG3716	PTS system mannose fructose sorbose family IID component
F3052_RS02880	COG3715	PTS system
F3052_RS02885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS02895	COG2222	sugar isomerase
F3052_RS02900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3052_RS02905	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS02910	COG3716	PTS system mannose fructose sorbose family IID component
F3052_RS02920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS02930	COG1349	DNA-binding transcription factor activity
F3052_RS02940	COG2002	toxin-antitoxin pair type II binding
F3052_RS02945	COG2721	sulfolactate sulfo-lyase activity
F3052_RS02950	COG2271	Major facilitator Superfamily
F3052_RS02960	COG2084	Dehydrogenase
F3052_RS02965	COG1929	Belongs to the glycerate kinase type-1 family
F3052_RS02990	COG0583	DNA-binding transcription factor activity
F3052_RS02995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3052_RS03005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F3052_RS03010	COG1882	Formate acetyltransferase
F3052_RS03015	COG0251	oxidation-reduction process
F3052_RS03020	COG1760	l-serine dehydratase
F3052_RS03045	COG1585	Membrane protein implicated in regulation of membrane protease activity
F3052_RS03050	COG2268	Band 7 protein
F3052_RS03075	COG3025	triphosphatase activity
F3052_RS03080	COG4991	sh3 domain protein
F3052_RS03095	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F3052_RS03105	COG0583	DNA-binding transcription factor activity
F3052_RS03110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F3052_RS03115	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F3052_RS03120	COG0471	metal ion transport
F3052_RS03130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3052_RS03135	COG0358	DNA primase activity
F3052_RS03140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3052_RS03155	COG2375	cellular response to nickel ion
F3052_RS03160	COG1695	Transcriptional regulator
F3052_RS03165	COG0840	transmembrane signaling receptor activity
F3052_RS03175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3052_RS03180	COG1609	Transcriptional regulator
F3052_RS03185	COG3250	beta-galactosidase activity
F3052_RS03190	COG2731	YhcH YjgK YiaL family protein
F3052_RS03195	COG0531	amino acid
F3052_RS03205	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
F3052_RS03205	COG3408	Glycogen debranching enzyme
F3052_RS03210	COG1902	pentaerythritol trinitrate reductase activity
F3052_RS03210	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3052_RS03215	COG5499	transcription regulator containing HTH domain
F3052_RS03220	COG4680	protein conserved in bacteria
F3052_RS03230	COG1451	nucleotide metabolic process
F3052_RS03235	COG2949	membrane
F3052_RS03240	COG0673	inositol 2-dehydrogenase activity
F3052_RS03245	COG0861	Integral membrane protein TerC family
F3052_RS03250	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
F3052_RS03260	COG2721	sulfolactate sulfo-lyase activity
F3052_RS03270	COG2271	Major facilitator Superfamily
F3052_RS03275	COG2186	Transcriptional regulator
F3052_RS03280	COG0586	Pfam SNARE associated Golgi protein
F3052_RS03290	COG1422	Protein of unknown function (DUF1090)
F3052_RS03295	COG4575	ribosome binding
F3052_RS03300	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
F3052_RS03310	COG2259	Doxx family
F3052_RS03315	COG0435	Glutathione S-transferase
F3052_RS03320	COG3152	Membrane
F3052_RS03325	COG3152	Membrane
F3052_RS03330	COG0583	DNA-binding transcription factor activity
F3052_RS03335	COG1741	Belongs to the pirin family
F3052_RS03355	COG3539	Fimbrial protein
F3052_RS03365	COG2960	long-chain fatty acid transporting porin activity
F3052_RS03385	COG3384	dioxygenase
F3052_RS03390	COG0754	glutathionylspermidine amidase activity
F3052_RS03400	COG1538	Outer membrane efflux protein
F3052_RS03405	COG0494	nUDIX hydrolase
F3052_RS03410	COG3151	Protein conserved in bacteria
F3052_RS03415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F3052_RS03420	COG3150	esterase
F3052_RS03425	COG0187	DNA topoisomerase II activity
F3052_RS03430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F3052_RS03435	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3052_RS03445	COG0642	Histidine kinase
F3052_RS03450	COG0745	RESPONSE REGULATOR receiver
F3052_RS03455	COG3111	PFAM Bacterial OB fold (BOF) protein
F3052_RS03460	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F3052_RS03470	COG2944	sequence-specific DNA binding
F3052_RS03475	COG4166	transmembrane transport
F3052_RS03480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3052_RS03485	COG0204	Acyl-transferase
F3052_RS03490	COG2132	Multicopper oxidase
F3052_RS03495	COG1032	radical SAM domain protein
F3052_RS03500	COG4238	major outer membrane lipoprotein
F3052_RS03510	COG0656	L-ascorbic acid biosynthetic process
F3052_RS03515	COG1979	alcohol dehydrogenase
F3052_RS03520	COG2207	Transcriptional regulator
F3052_RS03525	COG0586	Pfam SNARE associated Golgi protein
F3052_RS03530	COG0626	cystathionine gamma-synthase activity
F3052_RS03535	COG0811	peptide transport
F3052_RS03540	COG0848	biopolymer transport protein
F3052_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS03555	COG0667	Aldo Keto reductase
F3052_RS03570	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
F3052_RS03575	COG0437	4 iron, 4 sulfur cluster binding
F3052_RS03580	COG5557	Pfam Polysulphide reductase, NrfD
F3052_RS03585	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
F3052_RS03590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F3052_RS03595	COG1773	rubredoxin
F3052_RS03605	COG0298	carbon dioxide binding
F3052_RS03610	COG0625	glutathione transferase activity
F3052_RS03615	COG0754	glutathionylspermidine amidase activity
F3052_RS03620	COG0306	phosphate transporter
F3052_RS03625	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F3052_RS03630	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F3052_RS03635	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F3052_RS03640	COG2244	polysaccharide biosynthetic process
F3052_RS03650	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F3052_RS03655	COG0795	lipopolysaccharide-transporting ATPase activity
F3052_RS03665	COG0156	8-amino-7-oxononanoate synthase activity
F3052_RS03670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3052_RS03680	COG0318	PFAM AMP-dependent synthetase and ligase
F3052_RS03685	COG0456	acetyltransferase
F3052_RS03690	COG2186	Transcriptional regulator
F3052_RS03695	COG0277	FAD linked oxidase domain protein
F3052_RS03700	COG0277	FAD linked oxidase domain protein
F3052_RS03705	COG0247	lactate metabolic process
F3052_RS03710	COG3193	protein, possibly involved in utilization of glycolate and propanediol
F3052_RS03715	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F3052_RS03720	COG1620	l-lactate permease
F3052_RS03725	COG3064	Membrane
F3052_RS03730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
F3052_RS03740	COG3031	protein transport across the cell outer membrane
F3052_RS03750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3052_RS03755	COG1459	type II secretion system
F3052_RS03760	COG2165	general secretion pathway protein
F3052_RS03790	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
F3052_RS03800	COG1811	Na channel or pump
F3052_RS03805	COG1982	Orn Lys Arg decarboxylase major
F3052_RS03810	COG2211	Major facilitator Superfamily
F3052_RS03825	COG1194	a g-specific adenine glycosylase
F3052_RS03835	COG3171	Protein conserved in bacteria
F3052_RS03845	COG0252	asparaginase activity
F3052_RS03855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3052_RS03860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F3052_RS03870	COG0762	integral membrane protein
F3052_RS03875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F3052_RS03880	COG2805	Type II/IV secretion system protein
F3052_RS03895	COG0189	ligase activity
F3052_RS03900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F3052_RS03905	COG2356	endonuclease I
F3052_RS03915	COG2814	Major facilitator Superfamily
F3052_RS03935	COG1166	arginine decarboxylase activity
F3052_RS03945	COG0501	Belongs to the peptidase M48B family
F3052_RS03950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F3052_RS03955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS03960	COG2213	PTS system mannitol-specific
F3052_RS03965	COG1063	alcohol dehydrogenase
F3052_RS03970	COG1494	fructose-1,6-bisphosphatase
F3052_RS03975	COG3722	fumarate hydratase activity
F3052_RS03980	COG1072	(Pantothenic acid kinase))
F3052_RS03995	COG0191	fructose-bisphosphate aldolase activity
F3052_RS04000	COG0668	transmembrane transport
F3052_RS04005	COG1279	arginine transmembrane transporter activity
F3052_RS04010	COG2968	Membrane
F3052_RS04015	COG0583	DNA-binding transcription factor activity
F3052_RS04020	COG0427	acetyl-CoA hydrolase
F3052_RS04025	COG1024	Enoyl-CoA hydratase
F3052_RS04030	COG1703	isobutyryl-CoA mutase activity
F3052_RS04035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F3052_RS04035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F3052_RS04055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3052_RS04065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F3052_RS04085	COG0006	proline dipeptidase activity
F3052_RS04090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3052_RS04095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3052_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS04125	COG2723	6-phospho-beta-galactosidase activity
F3052_RS04135	COG1272	protein, Hemolysin III
F3052_RS04145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F3052_RS04155	COG0716	FMN binding
F3052_RS04160	COG4974	Belongs to the 'phage' integrase family
F3052_RS04165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3052_RS04170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F3052_RS04180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F3052_RS04200	COG2233	PERMEase
F3052_RS04205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS04205	COG0493	'glutamate synthase
F3052_RS04210	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS04215	COG2252	PERMEase
F3052_RS04220	COG0402	S-adenosylhomocysteine deaminase activity
F3052_RS04225	COG2233	PERMEase
F3052_RS04230	COG2080	2 iron, 2 sulfur cluster binding
F3052_RS04230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3052_RS04235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3052_RS04240	COG0402	S-adenosylhomocysteine deaminase activity
F3052_RS04245	COG0493	'glutamate synthase
F3052_RS04245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS04250	COG2068	MobA-Related Protein
F3052_RS04255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F3052_RS04260	COG3608	succinylglutamate desuccinylase aspartoacylase
F3052_RS04260	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F3052_RS04265	COG0549	Belongs to the carbamate kinase family
F3052_RS04275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3052_RS04280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3052_RS04285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F3052_RS04290	COG3829	transcription factor binding
F3052_RS04295	COG2080	2 iron, 2 sulfur cluster binding
F3052_RS04300	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3052_RS04305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3052_RS04310	COG4942	peptidase
F3052_RS04415	COG0457	Tetratricopeptide repeat
F3052_RS04415	COG3710	Transcriptional regulator
F3052_RS04430	COG0457	Tetratricopeptide repeat
F3052_RS04455	COG3710	Transcriptional regulator
F3052_RS04460	COG2771	luxR family
F3052_RS04465	COG0814	amino acid
F3052_RS04470	COG0183	Belongs to the thiolase family
F3052_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS04485	COG2814	Major facilitator Superfamily
F3052_RS04490	COG1794	racemase activity, acting on amino acids and derivatives
F3052_RS04495	COG0583	DNA-binding transcription factor activity
F3052_RS04505	COG1609	Transcriptional regulator
F3052_RS04520	COG0667	Aldo Keto reductase
F3052_RS04530	COG0861	Integral membrane protein TerC family
F3052_RS04545	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
F3052_RS04565	COG2165	general secretion pathway protein
F3052_RS04570	COG4795	General secretion pathway protein
F3052_RS04580	COG4967	type IV pilus modification protein PilV
F3052_RS04585	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F3052_RS04590	COG1025	Belongs to the peptidase M16 family
F3052_RS04595	COG1074	ATP-dependent DNA helicase activity
F3052_RS04600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3052_RS04605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F3052_RS04605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F3052_RS04610	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3052_RS04620	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F3052_RS04625	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F3052_RS04630	COG2166	iron-sulfur cluster assembly
F3052_RS04635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3052_RS04645	COG0583	DNA-binding transcription factor activity
F3052_RS04650	COG2363	Small membrane protein
F3052_RS04660	COG1349	DNA-binding transcription factor activity
F3052_RS04670	COG1070	Carbohydrate kinase
F3052_RS04680	COG0738	Major facilitator superfamily
F3052_RS04685	COG0235	Class ii aldolase
F3052_RS04690	COG1454	alcohol dehydrogenase
F3052_RS04700	COG1760	l-serine dehydratase
F3052_RS04705	COG0814	amino acid
F3052_RS04710	COG1611	Belongs to the LOG family
F3052_RS04725	COG3098	single-species biofilm formation
F3052_RS04730	COG0564	pseudouridine synthase activity
F3052_RS04735	COG0716	FMN binding
F3052_RS04740	COG2271	Major facilitator Superfamily
F3052_RS04750	COG4948	Mandelate Racemase Muconate Lactonizing
F3052_RS04755	COG4999	Histidine kinase
F3052_RS04755	COG2205	protein histidine kinase activity
F3052_RS04755	COG3850	Histidine kinase
F3052_RS04755	COG3437	response regulator, receiver
F3052_RS04760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F3052_RS04765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F3052_RS04770	COG2336	PFAM SpoVT AbrB
F3052_RS04775	COG2337	Toxic component of a toxin-antitoxin (TA) module
F3052_RS04780	COG3956	TIGRFAM MazG family protein
F3052_RS04795	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F3052_RS04805	COG0602	queuosine metabolic process
F3052_RS04810	COG1070	Carbohydrate kinase
F3052_RS04815	COG2223	nitrite transmembrane transporter activity
F3052_RS04820	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS04825	COG0277	FAD linked oxidase domain protein
F3052_RS04830	COG0477	Major facilitator Superfamily
F3052_RS04835	COG2086	electron transfer activity
F3052_RS04840	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F3052_RS04845	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
F3052_RS04850	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F3052_RS04855	COG0644	oxidoreductase
F3052_RS04860	COG0720	synthase
F3052_RS04870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3052_RS04885	COG3385	transposase activity
F3052_RS04890	COG1203	CRISPR-associated helicase, Cas3
F3052_RS04905	COG1857	crispr-associated protein
F3052_RS04920	COG1518	maintenance of DNA repeat elements
F3052_RS04925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3052_RS04930	COG2234	aminopeptidase activity
F3052_RS04985	COG1388	LysM domain
F3052_RS04985	COG4942	peptidase
F3052_RS04995	COG2610	gluconate transmembrane transporter activity
F3052_RS05000	COG3622	Belongs to the hyi family
F3052_RS05005	COG0235	Class ii aldolase
F3052_RS05010	COG3395	kinase activity
F3052_RS05015	COG2084	Dehydrogenase
F3052_RS05020	COG1349	DNA-binding transcription factor activity
F3052_RS05025	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3052_RS05045	COG3604	Transcriptional regulator
F3052_RS05050	COG0309	Hydrogenase expression formation protein (HypE)
F3052_RS05055	COG0409	Hydrogenase expression formation protein
F3052_RS05060	COG0298	carbon dioxide binding
F3052_RS05065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F3052_RS05070	COG0375	protein maturation
F3052_RS05080	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS05085	COG0651	ATP synthesis coupled electron transport
F3052_RS05090	COG0650	Formate hydrogenlyase subunit 4
F3052_RS05095	COG3261	NADH dehydrogenase
F3052_RS05095	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
F3052_RS05100	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3052_RS05105	COG3260	NADH ubiquinone oxidoreductase 20
F3052_RS05115	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F3052_RS05120	COG2723	6-phospho-beta-galactosidase activity
F3052_RS05125	COG1263	PTS System
F3052_RS05125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS05130	COG1609	Transcriptional regulator
F3052_RS05135	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS05140	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
F3052_RS05160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F3052_RS05160	COG0517	IMP dehydrogenase activity
F3052_RS05165	COG1349	DNA-binding transcription factor activity
F3052_RS05170	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS05175	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS05180	COG3731	PTS system glucitol sorbitol-specific IIA component
F3052_RS05185	COG3732	PTS system glucitol sorbitol-specific
F3052_RS05190	COG3730	PTS system glucitol sorbitol-specific
F3052_RS05195	COG2951	lytic endotransglycosylase activity
F3052_RS05200	COG1546	Belongs to the CinA family
F3052_RS05220	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F3052_RS05250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3052_RS05255	COG1238	metal cluster binding
F3052_RS05270	COG2814	Major facilitator Superfamily
F3052_RS05275	COG1566	PFAM secretion protein HlyD family protein
F3052_RS05280	COG1846	Transcriptional regulator
F3052_RS05290	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F3052_RS05295	COG2814	Major facilitator Superfamily
F3052_RS05300	COG2113	Glycine betaine
F3052_RS05305	COG4176	ABC-type proline glycine betaine transport system permease component
F3052_RS05310	COG4175	Glycine betaine
F3052_RS05315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3052_RS05320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3052_RS05330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3052_RS05335	COG4575	ribosome binding
F3052_RS05350	COG2916	Histone family protein nucleoid-structuring protein H-NS
F3052_RS05355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3052_RS05360	COG0640	Transcriptional regulator
F3052_RS05365	COG0401	homolog of Blt101
F3052_RS05370	COG1652	LysM domain
F3052_RS05375	COG1802	Transcriptional regulator
F3052_RS05380	COG1113	amino acid transport
F3052_RS05385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3052_RS05390	COG1012	belongs to the aldehyde dehydrogenase family
F3052_RS05395	COG0579	oxidoreductase
F3052_RS05410	COG0366	Alpha amylase catalytic
F3052_RS05435	COG3468	outer membrane autotransporter barrel domain protein
F3052_RS05450	COG2867	negative regulation of translational initiation
F3052_RS05460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3052_RS05465	COG0497	DNA recombination
F3052_RS05480	COG4536	flavin adenine dinucleotide binding
F3052_RS05485	COG4137	Cytochrome C assembly protein
F3052_RS05490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F3052_RS05515	COG2885	chlorophyll binding
F3052_RS05520	COG2199	diguanylate cyclase activity
F3052_RS05535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3052_RS05540	COG0287	Prephenate dehydrogenase
F3052_RS05540	COG1605	Chorismate mutase
F3052_RS05545	COG1605	Chorismate mutase
F3052_RS05545	COG0077	Prephenate dehydratase
F3052_RS05555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3052_RS05560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3052_RS05565	COG0564	pseudouridine synthase activity
F3052_RS05570	COG1496	oxidoreductase activity
F3052_RS05575	COG0542	response to heat
F3052_RS05600	COG0477	Major facilitator Superfamily
F3052_RS05605	COG5544	Lipoprotein
F3052_RS05610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3052_RS05615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3052_RS05615	COG0045	succinate-CoA ligase (ADP-forming) activity
F3052_RS05615	COG1042	CoA-binding domain protein
F3052_RS05620	COG3148	PFAM DTW domain containing protein
F3052_RS05625	COG3118	belongs to the thioredoxin family
F3052_RS05630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3052_RS05650	COG0583	DNA-binding transcription factor activity
F3052_RS05655	COG0513	Belongs to the DEAD box helicase family
F3052_RS05665	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F3052_RS05675	COG1595	DNA-templated transcription, initiation
F3052_RS05680	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
F3052_RS05685	COG3026	antisigma factor binding
F3052_RS05690	COG3086	response to oxidative stress
F3052_RS05700	COG0681	Belongs to the peptidase S26 family
F3052_RS05720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F3052_RS05735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS05740	COG1737	Transcriptional regulator
F3052_RS05745	COG0560	Phosphoserine phosphatase
F3052_RS05760	COG0047	phosphoribosylformylglycinamidine synthase activity
F3052_RS05760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3052_RS05765	COG2205	protein histidine kinase activity
F3052_RS05770	COG3170	Tfp pilus assembly protein FimV
F3052_RS05775	COG2204	response regulator
F3052_RS05780	COG0347	Belongs to the P(II) protein family
F3052_RS05785	COG1017	nitric oxide dioxygenase activity
F3052_RS05785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3052_RS05795	COG1940	carbohydrate kinase activity
F3052_RS05800	COG0457	Tetratricopeptide repeat
F3052_RS05805	COG1879	ABC-type sugar transport system periplasmic component
F3052_RS05815	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3052_RS05820	COG1063	alcohol dehydrogenase
F3052_RS05825	COG2017	converts alpha-aldose to the beta-anomer
F3052_RS05830	COG2259	Doxx family
F3052_RS05855	COG4638	Rieske (2fe-2S)
F3052_RS05860	COG0583	DNA-binding transcription factor activity
F3052_RS05865	COG2814	Major facilitator Superfamily
F3052_RS05870	COG3711	transcriptional antiterminator
F3052_RS05875	COG1073	alpha beta
F3052_RS05880	COG0483	inositol monophosphate 1-phosphatase activity
F3052_RS05900	COG0822	iron-sulfur transferase activity
F3052_RS05920	COG0633	Ferredoxin
F3052_RS05925	COG2975	iron-sulfur cluster assembly
F3052_RS05940	COG2897	thiosulfate sulfurtransferase activity
F3052_RS05945	COG2373	Large extracellular alpha-helical protein
F3052_RS05950	COG4953	penicillin-binding protein 1C
F3052_RS05980	COG2976	Protein conserved in bacteria
F3052_RS05995	COG1645	bacterial-type flagellum-dependent swarming motility
F3052_RS06005	COG0516	GMP reductase activity
F3052_RS06005	COG0517	IMP dehydrogenase activity
F3052_RS06020	COG3133	Outer membrane lipoprotein
F3052_RS06035	COG2200	EAL domain
F3052_RS06040	COG0248	Ppx GppA phosphatase
F3052_RS06045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F3052_RS06050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F3052_RS06065	COG2233	PERMEase
F3052_RS06075	COG1393	Belongs to the ArsC family
F3052_RS06080	COG4783	chaperone-mediated protein folding
F3052_RS06085	COG0628	permease
F3052_RS06090	COG2116	formate transmembrane transporter activity
F3052_RS06095	COG3604	Transcriptional regulator
F3052_RS06105	COG3260	NADH ubiquinone oxidoreductase 20
F3052_RS06110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3052_RS06115	COG3261	NADH dehydrogenase
F3052_RS06115	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
F3052_RS06120	COG0651	ATP synthesis coupled electron transport
F3052_RS06125	COG4237	Hydrogenase 4 membrane
F3052_RS06130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3052_RS06135	COG0650	Formate hydrogenlyase subunit 4
F3052_RS06140	COG0651	ATP synthesis coupled electron transport
F3052_RS06145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS06150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F3052_RS06155	COG2716	regulation of RNA biosynthetic process
F3052_RS06165	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F3052_RS06175	COG2321	neutral zinc metallopeptidase
F3052_RS06180	COG1444	tRNA N-acetyltransferase activity
F3052_RS06185	COG0400	carboxylic ester hydrolase activity
F3052_RS06200	COG1393	Belongs to the ArsC family
F3052_RS06210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3052_RS06215	COG3850	Histidine kinase
F3052_RS06220	COG0493	'glutamate synthase
F3052_RS06220	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS06230	COG5342	invasion associated locus B
F3052_RS06235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F3052_RS06240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3052_RS06245	COG0281	malic enzyme
F3052_RS06245	COG0280	phosphate acetyltransferase
F3052_RS06250	COG4810	utilization protein
F3052_RS06255	COG4917	ethanolamine utilization protein
F3052_RS06260	COG4766	ethanolamine catabolic process
F3052_RS06265	COG4812	Cobalamin adenosyltransferase
F3052_RS06270	COG0280	phosphate acetyltransferase
F3052_RS06275	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
F3052_RS06280	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
F3052_RS06285	COG1012	belongs to the aldehyde dehydrogenase family
F3052_RS06290	COG4820	ethanolamine utilization protein (EutJ)
F3052_RS06295	COG1454	alcohol dehydrogenase
F3052_RS06300	COG3192	ethanolamine utilization protein
F3052_RS06305	COG4819	ethanolamine utilization protein
F3052_RS06310	COG4303	Ethanolamine ammonia lyase large subunit
F3052_RS06320	COG4816	utilization protein
F3052_RS06325	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
F3052_RS06330	COG2207	Transcriptional regulator
F3052_RS06340	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3052_RS06345	COG0456	acetyltransferase
F3052_RS06360	COG2837	iron assimilation
F3052_RS06365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3052_RS06370	COG1263	PTS System
F3052_RS06370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS06390	COG4150	thiosulfate binding
F3052_RS06395	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F3052_RS06400	COG4208	sulfate ABC transporter
F3052_RS06405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3052_RS06410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3052_RS06415	COG3831	ATPase activity
F3052_RS06415	COG4884	unkown
F3052_RS06430	COG2190	(PTS) system
F3052_RS06435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3052_RS06440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS06445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3052_RS06465	COG3530	Putative quorum-sensing-regulated virulence factor
F3052_RS06470	COG0385	Bile acid
F3052_RS06475	COG0583	DNA-binding transcription factor activity
F3052_RS06485	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F3052_RS06490	COG2211	Major facilitator Superfamily
F3052_RS06500	COG0583	DNA-binding transcription factor activity
F3052_RS06530	COG3415	Transposase
F3052_RS06535	COG3415	Transposase
F3052_RS06550	COG2200	EAL domain
F3052_RS06550	COG2199	diguanylate cyclase activity
F3052_RS06555	COG3385	transposase activity
F3052_RS06560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3052_RS06585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS06590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS06595	COG0006	proline dipeptidase activity
F3052_RS06600	COG1363	Peptidase, m42
F3052_RS06605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3052_RS06605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS06605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS06610	COG2207	Transcriptional regulator
F3052_RS06615	COG3279	Response regulator of the LytR AlgR family
F3052_RS06620	COG3275	phosphorelay sensor kinase activity
F3052_RS06625	COG0436	Aminotransferase
F3052_RS06635	COG1560	Kdo2-lipid A biosynthetic process
F3052_RS06660	COG0028	Belongs to the TPP enzyme family
F3052_RS06665	COG0679	Auxin Efflux Carrier
F3052_RS06670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F3052_RS06675	COG2205	protein histidine kinase activity
F3052_RS06675	COG2198	Histidine kinase
F3052_RS06675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3052_RS06675	COG0784	Response regulator, receiver
F3052_RS06680	COG2197	response regulator
F3052_RS06685	COG1566	PFAM secretion protein HlyD family protein
F3052_RS06690	COG0477	Major facilitator Superfamily
F3052_RS06700	COG2610	gluconate transmembrane transporter activity
F3052_RS06705	COG0583	DNA-binding transcription factor activity
F3052_RS06715	COG2116	formate transmembrane transporter activity
F3052_RS06720	COG2853	Lipoprotein
F3052_RS06730	COG2067	long-chain fatty acid transport protein
F3052_RS06735	COG3691	Protein conserved in bacteria
F3052_RS06750	COG2062	phosphohistidine phosphatase, SixA
F3052_RS06755	COG3539	Fimbrial protein
F3052_RS06760	COG3188	usher protein
F3052_RS06765	COG3121	Chaperone
F3052_RS06770	COG3539	Fimbrial protein
F3052_RS06775	COG3539	Fimbrial protein
F3052_RS06780	COG3539	Fimbrial protein
F3052_RS06795	COG2890	protein-(glutamine-N5) methyltransferase activity
F3052_RS06810	COG0730	response to heat
F3052_RS06815	COG3101	peptidyl-lysine hydroxylation
F3052_RS06830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3052_RS06835	COG2814	Major facilitator Superfamily
F3052_RS06850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3052_RS06860	COG0586	Pfam SNARE associated Golgi protein
F3052_RS06870	COG0285	dihydrofolate synthase activity
F3052_RS06875	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F3052_RS06880	COG1286	toxin biosynthetic process
F3052_RS06885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3052_RS06890	COG0163	prenyltransferase activity
F3052_RS06895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3052_RS06900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3052_RS06905	COG4215	(ABC) transporter
F3052_RS06910	COG4160	amino acid transport
F3052_RS06915	COG4598	ABC transporter
F3052_RS06920	COG5464	transposase or invertase
F3052_RS06925	COG1090	epimerase
F3052_RS06930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F3052_RS06935	COG0625	glutathione transferase activity
F3052_RS06940	COG0625	glutathione transferase activity
F3052_RS06945	COG0622	Phosphoesterase
F3052_RS06950	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
F3052_RS06955	COG1288	antiporter activity
F3052_RS06960	COG0857	belongs to the CobB CobQ family
F3052_RS06960	COG0280	phosphate acetyltransferase
F3052_RS06965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F3052_RS06980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3052_RS06985	COG0471	metal ion transport
F3052_RS06985	COG0490	domain, Protein
F3052_RS06995	COG0436	Aminotransferase
F3052_RS07000	COG0583	DNA-binding transcription factor activity
F3052_RS07020	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F3052_RS07025	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F3052_RS07030	COG1034	ATP synthesis coupled electron transport
F3052_RS07045	COG0839	Belongs to the complex I subunit 6 family
F3052_RS07055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3052_RS07060	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3052_RS07070	COG0457	Tetratricopeptide repeat
F3052_RS07090	COG2234	aminopeptidase activity
F3052_RS07095	COG2304	oxidoreductase activity
F3052_RS07110	COG2153	protein acetylation
F3052_RS07115	COG4575	ribosome binding
F3052_RS07120	COG1169	isochorismate synthase
F3052_RS07135	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F3052_RS07145	COG0318	PFAM AMP-dependent synthetase and ligase
F3052_RS07210	COG1414	Transcriptional regulator
F3052_RS07220	COG2271	Major facilitator Superfamily
F3052_RS07235	COG5464	transposase or invertase
F3052_RS07240	COG0247	lactate metabolic process
F3052_RS07250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3052_RS07255	COG2271	Major facilitator Superfamily
F3052_RS07260	COG0584	glycerophosphoryl diester phosphodiesterase
F3052_RS07270	COG3642	lipopolysaccharide core region biosynthetic process
F3052_RS07275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3052_RS07280	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3052_RS07285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3052_RS07290	COG3468	outer membrane autotransporter barrel domain protein
F3052_RS07300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3052_RS07305	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
F3052_RS07310	COG3234	Protein of unknown function (DUF1175)
F3052_RS07315	COG2373	Large extracellular alpha-helical protein
F3052_RS07320	COG5445	Predicted secreted protein (DUF2300)
F3052_RS07325	COG4676	Protein conserved in bacteria
F3052_RS07330	COG0183	Belongs to the thiolase family
F3052_RS07335	COG2031	fatty acid transporter
F3052_RS07340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3052_RS07350	COG2204	response regulator
F3052_RS07355	COG3852	Histidine kinase
F3052_RS07360	COG2205	protein histidine kinase activity
F3052_RS07360	COG0784	Response regulator, receiver
F3052_RS07365	COG2197	response regulator
F3052_RS07370	COG2198	Histidine kinase
F3052_RS07370	COG0642	Histidine kinase
F3052_RS07375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F3052_RS07380	COG1477	protein flavinylation
F3052_RS07385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3052_RS07385	COG2169	Transcriptional regulator
F3052_RS07390	COG3145	DNA-N1-methyladenine dioxygenase activity
F3052_RS07395	COG4615	Cyclic peptide transporter
F3052_RS07415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS07415	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3052_RS07420	COG3062	negative regulation of establishment of protein localization
F3052_RS07430	COG0437	4 iron, 4 sulfur cluster binding
F3052_RS07435	COG0348	domain, Protein
F3052_RS07440	COG3043	anaerobic respiration
F3052_RS07445	COG3005	denitrification pathway
F3052_RS07450	COG4133	protoheme IX ABC transporter activity
F3052_RS07455	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3052_RS07460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3052_RS07465	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3052_RS07475	COG1138	Cytochrome C-type biogenesis protein
F3052_RS07480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3052_RS07485	COG4235	cytochrome complex assembly
F3052_RS07485	COG3088	subunit of a heme lyase
F3052_RS07490	COG2197	response regulator
F3052_RS07500	COG3468	outer membrane autotransporter barrel domain protein
F3052_RS07510	COG3083	sulfuric ester hydrolase activity
F3052_RS07530	COG1061	Type III restriction enzyme res subunit
F3052_RS07535	COG1187	pseudouridine synthase activity
F3052_RS07540	COG2814	Major facilitator Superfamily
F3052_RS07550	COG4172	Belongs to the ABC transporter superfamily
F3052_RS07555	COG4239	(ABC) transporter, permease
F3052_RS07560	COG4174	ABC transporter (Permease)
F3052_RS07565	COG4166	transmembrane transport
F3052_RS07570	COG2200	EAL domain
F3052_RS07575	COG0791	NLP P60 protein
F3052_RS07580	COG0671	phosphoesterase, PA-phosphatase related
F3052_RS07585	COG0523	cobalamin synthesis protein
F3052_RS07590	COG0246	Mannitol dehydrogenase
F3052_RS07605	COG2814	Major facilitator Superfamily
F3052_RS07610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS07610	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS07615	COG1105	Belongs to the carbohydrate kinase PfkB family
F3052_RS07620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS07620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS07620	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F3052_RS07625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3052_RS07630	COG2313	pseudouridylate synthase activity
F3052_RS07635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3052_RS07640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3052_RS07650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3052_RS07655	COG1522	sequence-specific DNA binding
F3052_RS07655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3052_RS07665	COG2855	membrane
F3052_RS07670	COG0583	DNA-binding transcription factor activity
F3052_RS07675	COG0833	amino acid
F3052_RS07680	COG4771	TonB-dependent receptor
F3052_RS07695	COG2311	Membrane
F3052_RS07700	COG1609	Transcriptional regulator
F3052_RS07705	COG1879	ABC-type sugar transport system periplasmic component
F3052_RS07710	COG1129	ABC transporter
F3052_RS07715	COG4211	Belongs to the binding-protein-dependent transport system permease family
F3052_RS07720	COG0167	dihydroorotate dehydrogenase activity
F3052_RS07720	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F3052_RS07725	COG0493	'glutamate synthase
F3052_RS07735	COG2949	membrane
F3052_RS07745	COG1346	cytolysis
F3052_RS07755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3052_RS07770	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS07775	COG0586	Pfam SNARE associated Golgi protein
F3052_RS07785	COG1686	Belongs to the peptidase S11 family
F3052_RS07790	COG0277	FAD linked oxidase domain protein
F3052_RS07795	COG1472	Belongs to the glycosyl hydrolase 3 family
F3052_RS07800	COG1732	Glycine betaine
F3052_RS07805	COG1174	glycine betaine transport
F3052_RS07810	COG1125	glycine betaine transport
F3052_RS07815	COG1174	glycine betaine transport
F3052_RS07825	COG0789	Transcriptional regulator
F3052_RS07830	COG3275	phosphorelay sensor kinase activity
F3052_RS07835	COG3279	Response regulator of the LytR AlgR family
F3052_RS07840	COG4807	Protein conserved in bacteria
F3052_RS07845	COG4808	Protein conserved in bacteria
F3052_RS07850	COG4715	Zinc finger, swim domain protein
F3052_RS07855	COG3552	Protein containing von Willebrand factor type A (VWA) domain
F3052_RS07860	COG2425	protein containing a von Willebrand factor type A (vWA) domain
F3052_RS07865	COG0714	Associated with various cellular activities
F3052_RS07875	COG3831	ATPase activity
F3052_RS07880	COG3831	ATPase activity
F3052_RS07890	COG0489	protein tyrosine kinase activity
F3052_RS07900	COG3539	Fimbrial protein
F3052_RS07905	COG3121	Chaperone
F3052_RS07910	COG3188	usher protein
F3052_RS07915	COG3539	Fimbrial protein
F3052_RS07920	COG5455	response to cobalt ion
F3052_RS07925	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F3052_RS07940	COG0351	phosphomethylpyrimidine kinase
F3052_RS07945	COG3757	hydrolase, family 25
F3052_RS07950	COG2188	Transcriptional regulator
F3052_RS07955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3052_RS07960	COG1397	ADP-ribosylglycohydrolase
F3052_RS07965	COG2211	Major facilitator Superfamily
F3052_RS07970	COG1830	Aldolase
F3052_RS07985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS07990	COG3414	Phosphotransferase system galactitol-specific IIB component
F3052_RS07995	COG3775	system Galactitol-specific IIC component
F3052_RS08000	COG1063	alcohol dehydrogenase
F3052_RS08020	COG0826	peptidase U32
F3052_RS08030	COG0745	RESPONSE REGULATOR receiver
F3052_RS08035	COG2205	protein histidine kinase activity
F3052_RS08075	COG4245	von Willebrand factor, type A
F3052_RS08080	COG0631	protein serine/threonine phosphatase activity
F3052_RS08085	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
F3052_RS08090	COG0443	Heat shock 70 kDa protein
F3052_RS08095	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F3052_RS08100	COG3447	MASE1 domain protein
F3052_RS08100	COG5001	Diguanylate cyclase
F3052_RS08100	COG5002	protein histidine kinase activity
F3052_RS08105	COG0572	uridine kinase
F3052_RS08115	COG2982	Protein involved in outer membrane biogenesis
F3052_RS08120	COG1253	flavin adenine dinucleotide binding
F3052_RS08130	COG1596	polysaccharide export
F3052_RS08135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3052_RS08140	COG0489	protein tyrosine kinase activity
F3052_RS08140	COG3206	protein involved in exopolysaccharide biosynthesis
F3052_RS08145	COG0463	Glycosyl transferase, family 2
F3052_RS08150	COG1045	serine acetyltransferase
F3052_RS08155	COG0438	transferase activity, transferring glycosyl groups
F3052_RS08165	COG1216	Glycosyl transferase, family 2
F3052_RS08170	COG0110	maltose O-acetyltransferase activity
F3052_RS08175	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
F3052_RS08180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3052_RS08185	COG1051	belongs to the nudix hydrolase family
F3052_RS08190	COG0297	glycogen (starch) synthase activity
F3052_RS08195	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F3052_RS08195	COG0662	Cupin 2, conserved barrel domain protein
F3052_RS08200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3052_RS08205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3052_RS08210	COG2244	polysaccharide biosynthetic process
F3052_RS08215	COG2327	Polysaccharide pyruvyl transferase
F3052_RS08220	COG0438	transferase activity, transferring glycosyl groups
F3052_RS08230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3052_RS08235	COG1088	dTDP-glucose 4,6-dehydratase activity
F3052_RS08240	COG1091	dTDP-4-dehydrorhamnose reductase activity
F3052_RS08245	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F3052_RS08255	COG2244	polysaccharide biosynthetic process
F3052_RS08260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F3052_RS08305	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F3052_RS08310	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3052_RS08315	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
F3052_RS08335	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3052_RS08340	COG0131	Imidazoleglycerol-phosphate dehydratase
F3052_RS08340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F3052_RS08365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3052_RS08370	COG0583	DNA-binding transcription factor activity
F3052_RS08380	COG0531	amino acid
F3052_RS08385	COG2391	methyltransferase activity
F3052_RS08390	COG0425	Belongs to the sulfur carrier protein TusA family
F3052_RS08395	COG2925	Exonuclease
F3052_RS08400	COG1686	Belongs to the peptidase S11 family
F3052_RS08410	COG1289	transmembrane transporter activity
F3052_RS08420	COG4917	ethanolamine utilization protein
F3052_RS08465	COG2003	Belongs to the UPF0758 family
F3052_RS08485	COG3436	PFAM IS66 Orf2 family protein
F3052_RS08490	COG4372	Transposase
F3052_RS08505	COG4584	PFAM Integrase catalytic
F3052_RS08510	COG1484	DNA-dependent DNA replication
F3052_RS08605	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
F3052_RS08620	COG1376	ErfK ybiS ycfS ynhG family protein
F3052_RS08630	COG0583	DNA-binding transcription factor activity
F3052_RS08635	COG0583	DNA-binding transcription factor activity
F3052_RS08645	COG0534	Mate efflux family protein
F3052_RS08655	COG0217	transcriptional regulatory protein
F3052_RS08660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3052_RS08665	COG0477	Major facilitator Superfamily
F3052_RS08680	COG2826	transposase and inactivated derivatives, IS30 family
F3052_RS08710	COG3038	cytochrome b561
F3052_RS08715	COG3443	Belongs to the bacterial solute-binding protein 9 family
F3052_RS08730	COG2351	hydroxyisourate hydrolase activity
F3052_RS08735	COG0745	RESPONSE REGULATOR receiver
F3052_RS08740	COG2205	protein histidine kinase activity
F3052_RS08750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F3052_RS08760	COG1418	mRNA catabolic process
F3052_RS08765	COG0270	DNA (cytosine-5-)-methyltransferase activity
F3052_RS08770	COG3727	T/G mismatch-specific endonuclease activity
F3052_RS08775	COG0697	spore germination
F3052_RS08780	COG2354	Protein conserved in bacteria
F3052_RS08785	COG5475	Uncharacterized small protein (DUF2158)
F3052_RS08810	COG2197	response regulator
F3052_RS08815	COG1684	flagellar biosynthetic protein fliR
F3052_RS08820	COG1987	bacterial-type flagellum assembly
F3052_RS08825	COG1338	Plays a role in the flagellum-specific transport system
F3052_RS08830	COG3190	flagellar
F3052_RS08835	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3052_RS08840	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3052_RS08845	COG1580	Controls the rotational direction of flagella during chemotaxis
F3052_RS08850	COG3144	bacterial-type flagellum assembly
F3052_RS08855	COG2882	bacterial-type flagellum organization
F3052_RS08860	COG1157	protein secretion by the type III secretion system
F3052_RS08865	COG1317	bacterial-type flagellum organization
F3052_RS08870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3052_RS08875	COG1766	The M ring may be actively involved in energy transduction
F3052_RS08885	COG2135	peptidase activity
F3052_RS08890	COG0425	Belongs to the sulfur carrier protein TusA family
F3052_RS08895	COG2391	methyltransferase activity
F3052_RS08905	COG0366	Alpha amylase catalytic
F3052_RS08915	COG1516	flagellar protein fliS
F3052_RS08920	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F3052_RS08930	COG1191	sigma factor activity
F3052_RS08940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3052_RS08950	COG0765	amino acid transport
F3052_RS08955	COG1126	abc transporter atp-binding protein
F3052_RS08960	COG2197	response regulator
F3052_RS08975	COG2197	response regulator
F3052_RS09005	COG3012	SEC-C Motif Domain Protein
F3052_RS09005	COG3318	Belongs to the UPF0149 family
F3052_RS09010	COG0814	amino acid
F3052_RS09020	COG1528	Iron-storage protein
F3052_RS09040	COG1528	Iron-storage protein
F3052_RS09045	COG1879	ABC-type sugar transport system periplasmic component
F3052_RS09050	COG1129	ABC transporter
F3052_RS09055	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3052_RS09060	COG1877	trehalose-phosphatase activity
F3052_RS09070	COG0589	response to stress
F3052_RS09085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F3052_RS09090	COG1360	Flagellar Motor Protein
F3052_RS09095	COG2198	Histidine kinase
F3052_RS09095	COG0643	Histidine kinase
F3052_RS09100	COG0835	chemotaxis
F3052_RS09105	COG0840	transmembrane signaling receptor activity
F3052_RS09110	COG0840	transmembrane signaling receptor activity
F3052_RS09115	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F3052_RS09120	COG2201	protein-glutamate methylesterase activity
F3052_RS09125	COG0745	RESPONSE REGULATOR receiver
F3052_RS09130	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
F3052_RS09135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3052_RS09140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3052_RS09150	COG3755	Protein conserved in bacteria
F3052_RS09160	COG3102	Protein conserved in bacteria
F3052_RS09170	COG3005	denitrification pathway
F3052_RS09175	COG0243	molybdopterin cofactor binding
F3052_RS09190	COG3788	relative of glutathione S-transferase, MAPEG superfamily
F3052_RS09195	COG1801	Protein of unknown function DUF72
F3052_RS09200	COG1335	isochorismatase
F3052_RS09210	COG0494	nUDIX hydrolase
F3052_RS09215	COG0217	transcriptional regulatory protein
F3052_RS09245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3052_RS09255	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F3052_RS09260	COG0739	heme binding
F3052_RS09265	COG1560	Kdo2-lipid A biosynthetic process
F3052_RS09270	COG0469	pyruvate kinase activity
F3052_RS09275	COG1737	Transcriptional regulator
F3052_RS09280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3052_RS09285	COG0129	dihydroxy-acid dehydratase activity
F3052_RS09290	COG0800	Aldolase
F3052_RS09300	COG3141	response to X-ray
F3052_RS09310	COG2979	Protein of unknown function (DUF533)
F3052_RS09315	COG1770	oligopeptidase
F3052_RS09320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3052_RS09325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3052_RS09335	COG2372	response to copper ion
F3052_RS09340	COG1276	copper resistance
F3052_RS09350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3052_RS09370	COG3008	intermembrane lipid transfer
F3052_RS09375	COG2995	paraquat-inducible protein a
F3052_RS09380	COG1956	GAF domain-containing protein
F3052_RS09390	COG0793	Belongs to the peptidase S41A family
F3052_RS09400	COG2814	Major facilitator Superfamily
F3052_RS09405	COG1414	Transcriptional regulator
F3052_RS09435	COG2226	methyltransferase
F3052_RS09450	COG3716	PTS system mannose fructose sorbose family IID component
F3052_RS09455	COG3715	PTS system
F3052_RS09460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS09460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS09465	COG1253	flavin adenine dinucleotide binding
F3052_RS09470	COG2200	EAL domain
F3052_RS09475	COG1760	l-serine dehydratase
F3052_RS09485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3052_RS09500	COG0251	oxidation-reduction process
F3052_RS09505	COG1199	ATP-dependent helicase activity
F3052_RS09510	COG1214	PFAM Peptidase M22, glycoprotease
F3052_RS09515	COG3065	identical protein binding
F3052_RS09520	COG0318	PFAM AMP-dependent synthetase and ligase
F3052_RS09525	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F3052_RS09530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3052_RS09535	COG4638	Rieske (2fe-2S)
F3052_RS09545	COG0473	3-isopropylmalate dehydrogenase activity
F3052_RS09550	COG0583	DNA-binding transcription factor activity
F3052_RS09560	COG3615	Tellurite resistance protein tehB
F3052_RS09570	COG2261	transglycosylase associated protein
F3052_RS09585	COG2199	diguanylate cyclase activity
F3052_RS09585	COG2203	Gaf domain
F3052_RS09590	COG3042	response to heat
F3052_RS09595	COG3189	MarR family transcriptional regulator
F3052_RS09600	COG2807	transmembrane transport
F3052_RS09605	COG2207	Transcriptional regulator
F3052_RS09620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3052_RS09625	COG2199	diguanylate cyclase activity
F3052_RS09630	COG2199	diguanylate cyclase activity
F3052_RS09640	COG2766	serine protein kinase
F3052_RS09645	COG3713	MltA-interacting MipA family protein
F3052_RS09650	COG0656	L-ascorbic acid biosynthetic process
F3052_RS09655	COG0676	glucose-6-phosphate 1-epimerase activity
F3052_RS09660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F3052_RS09670	COG3139	Protein of unknown function (DUF1315)
F3052_RS09675	COG1063	alcohol dehydrogenase
F3052_RS09680	COG2271	Major facilitator Superfamily
F3052_RS09685	COG1063	alcohol dehydrogenase
F3052_RS09690	COG0191	fructose-bisphosphate aldolase activity
F3052_RS09695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3052_RS09700	COG0667	Aldo Keto reductase
F3052_RS09705	COG1349	DNA-binding transcription factor activity
F3052_RS09710	COG2814	Major facilitator Superfamily
F3052_RS09715	COG1335	isochorismatase
F3052_RS09720	COG0252	asparaginase activity
F3052_RS09725	COG0616	signal peptide processing
F3052_RS09730	COG0778	Nitroreductase
F3052_RS09740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3052_RS09750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3052_RS09760	COG0494	nUDIX hydrolase
F3052_RS09765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3052_RS09770	COG2897	thiosulfate sulfurtransferase activity
F3052_RS09775	COG4136	ATPase activity
F3052_RS09780	COG4135	transport system, permease component
F3052_RS09785	COG4134	Bacterial extracellular solute-binding protein
F3052_RS09790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3052_RS09795	COG0398	Pfam SNARE associated Golgi protein
F3052_RS09805	COG0398	Pfam SNARE associated Golgi protein
F3052_RS09810	COG0708	Exodeoxyribonuclease III
F3052_RS09840	COG3678	ATP-independent chaperone mediated protein folding
F3052_RS09850	COG0322	excinuclease ABC activity
F3052_RS09860	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3052_RS09865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3052_RS09870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3052_RS09875	COG1447	Phosphotransferase system cellobiose-specific component IIA
F3052_RS09880	COG1917	Cupin 2, conserved barrel domain protein
F3052_RS09880	COG2169	Transcriptional regulator
F3052_RS09885	COG1486	melibiose metabolic process
F3052_RS09895	COG0753	catalase activity
F3052_RS09910	COG1823	symporter activity
F3052_RS09915	COG1988	membrane-bound metal-dependent
F3052_RS09920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3052_RS09930	COG3001	Fructosamine kinase
F3052_RS09940	COG1105	Belongs to the carbohydrate kinase PfkB family
F3052_RS09945	COG3137	Salt-induced outer membrane protein
F3052_RS09990	COG0072	phenylalanine-tRNA ligase activity
F3052_RS09990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3052_RS10005	COG0386	Belongs to the glutathione peroxidase family
F3052_RS10015	COG0791	NLP P60 protein
F3052_RS10020	COG2200	EAL domain
F3052_RS10030	COG4256	Hemin uptake protein
F3052_RS10035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3052_RS10045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3052_RS10045	COG0574	Belongs to the PEP-utilizing enzyme family
F3052_RS10050	COG0318	PFAM AMP-dependent synthetase and ligase
F3052_RS10055	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F3052_RS10060	COG0644	oxidoreductase
F3052_RS10065	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F3052_RS10070	COG2086	electron transfer activity
F3052_RS10075	COG1917	Cupin 2, conserved barrel domain protein
F3052_RS10075	COG2207	Transcriptional regulator
F3052_RS10080	COG1960	acyl-CoA dehydrogenase activity
F3052_RS10085	COG4670	ketone body catabolic process
F3052_RS10100	COG2271	Major facilitator Superfamily
F3052_RS10105	COG0738	Major facilitator superfamily
F3052_RS10120	COG0628	permease
F3052_RS10125	COG0277	FAD linked oxidase domain protein
F3052_RS10125	COG0247	lactate metabolic process
F3052_RS10130	COG2050	protein possibly involved in aromatic compounds catabolism
F3052_RS10140	COG0316	Belongs to the HesB IscA family
F3052_RS10145	COG0719	Fe-S assembly protein
F3052_RS10150	COG0396	ATPase activity
F3052_RS10155	COG0719	Fe-S assembly protein
F3052_RS10170	COG1376	ErfK ybiS ycfS ynhG family protein
F3052_RS10175	COG4238	major outer membrane lipoprotein
F3052_RS10180	COG0469	pyruvate kinase activity
F3052_RS10190	COG0437	4 iron, 4 sulfur cluster binding
F3052_RS10195	COG2414	aldehyde ferredoxin oxidoreductase
F3052_RS10205	COG0437	4 iron, 4 sulfur cluster binding
F3052_RS10210	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
F3052_RS10220	COG4529	Protein conserved in bacteria
F3052_RS10240	COG3468	outer membrane autotransporter barrel domain protein
F3052_RS10250	COG0307	riboflavin synthase, alpha
F3052_RS10255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3052_RS10260	COG2814	Major facilitator Superfamily
F3052_RS10265	COG0583	DNA-binding transcription factor activity
F3052_RS10280	COG2814	Major facilitator Superfamily
F3052_RS10285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3052_RS10290	COG0791	NLP P60 protein
F3052_RS10295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F3052_RS10300	COG1201	RNA secondary structure unwinding
F3052_RS10305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3052_RS10310	COG0346	lactoylglutathione lyase activity
F3052_RS10315	COG1902	pentaerythritol trinitrate reductase activity
F3052_RS10320	COG1309	transcriptional regulator
F3052_RS10325	COG3313	Fe-S protein
F3052_RS10330	COG4989	oxidoreductase activity
F3052_RS10335	COG2032	superoxide dismutase activity
F3052_RS10340	COG1289	transmembrane transporter activity
F3052_RS10345	COG1566	PFAM secretion protein HlyD family protein
F3052_RS10360	COG3133	Outer membrane lipoprotein
F3052_RS10370	COG3895	Periplasmic Protein
F3052_RS10385	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F3052_RS10390	COG0625	glutathione transferase activity
F3052_RS10395	COG3104	oligopeptide transport
F3052_RS10400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F3052_RS10410	COG4659	FMN binding
F3052_RS10450	COG0673	inositol 2-dehydrogenase activity
F3052_RS10460	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F3052_RS10465	COG1263	PTS System
F3052_RS10465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS10470	COG1609	Transcriptional regulator
F3052_RS10475	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS10480	COG1309	transcriptional regulator
F3052_RS10485	COG3250	beta-galactosidase activity
F3052_RS10500	COG5339	Protein conserved in bacteria
F3052_RS10505	COG1482	cell wall glycoprotein biosynthetic process
F3052_RS10510	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F3052_RS10510	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F3052_RS10515	COG0114	fumarate hydratase activity
F3052_RS10525	COG2205	protein histidine kinase activity
F3052_RS10530	COG0745	RESPONSE REGULATOR receiver
F3052_RS10535	COG3136	membrane protein required for alginate biosynthesis
F3052_RS10545	COG0531	amino acid
F3052_RS10555	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F3052_RS10560	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F3052_RS10565	COG0628	permease
F3052_RS10580	COG3591	Belongs to the peptidase S1B family
F3052_RS10595	COG2814	Major facilitator Superfamily
F3052_RS10605	COG1940	carbohydrate kinase activity
F3052_RS10610	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F3052_RS10620	COG3381	protein complex oligomerization
F3052_RS10625	COG3302	dmso reductase anchor subunit
F3052_RS10630	COG0437	4 iron, 4 sulfur cluster binding
F3052_RS10635	COG0243	molybdopterin cofactor binding
F3052_RS10640	COG0243	molybdopterin cofactor binding
F3052_RS10655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3052_RS10670	COG4948	Mandelate Racemase Muconate Lactonizing
F3052_RS10675	COG1063	alcohol dehydrogenase
F3052_RS10685	COG0582	viral genome integration into host DNA
F3052_RS10720	COG1396	sequence-specific DNA binding
F3052_RS10735	COG1846	Transcriptional regulator
F3052_RS10750	COG2801	Transposase and inactivated derivatives
F3052_RS10765	COG3077	Addiction module antitoxin, RelB DinJ family
F3052_RS10770	COG2026	Addiction module toxin, RelE StbE family
F3052_RS10790	COG1403	HNH endonuclease
F3052_RS10795	COG0484	heat shock protein binding
F3052_RS10805	COG1278	Cold shock
F3052_RS10810	COG1278	Cold shock
F3052_RS10825	COG3772	lysozyme
F3052_RS10835	COG1278	Cold shock
F3052_RS10865	COG5562	phage envelope protein
F3052_RS10875	COG4220	transposase activity
F3052_RS10895	COG1030	water channel activity
F3052_RS10945	COG1196	nuclear chromosome segregation
F3052_RS10980	COG5301	cellulose 1,4-beta-cellobiosidase activity
F3052_RS10985	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
F3052_RS10990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3052_RS11010	COG0246	Mannitol dehydrogenase
F3052_RS11020	COG1802	Transcriptional regulator
F3052_RS11025	COG4221	oxidoreductase activity
F3052_RS11030	COG0339	signal peptide processing
F3052_RS11035	COG1546	Belongs to the CinA family
F3052_RS11040	COG3111	PFAM Bacterial OB fold (BOF) protein
F3052_RS11045	COG3706	GGDEF domain
F3052_RS11055	COG2814	Major facilitator Superfamily
F3052_RS11060	COG0697	spore germination
F3052_RS11070	COG4977	sequence-specific DNA binding
F3052_RS11075	COG1846	Transcriptional regulator
F3052_RS11105	COG0583	DNA-binding transcription factor activity
F3052_RS11110	COG1012	belongs to the aldehyde dehydrogenase family
F3052_RS11115	COG2066	Belongs to the glutaminase family
F3052_RS11135	COG3781	membrane
F3052_RS11195	COG3210	domain, Protein
F3052_RS11195	COG2911	Protein conserved in bacteria
F3052_RS11200	COG1396	sequence-specific DNA binding
F3052_RS11205	COG3550	peptidyl-serine autophosphorylation
F3052_RS11230	COG3539	Fimbrial protein
F3052_RS11235	COG3539	Fimbrial protein
F3052_RS11240	COG3539	Fimbrial protein
F3052_RS11245	COG0243	molybdopterin cofactor binding
F3052_RS11255	COG2207	Transcriptional regulator
F3052_RS11260	COG3119	arylsulfatase activity
F3052_RS11265	COG0641	radical SAM
F3052_RS11275	COG4178	(ABC) transporter
F3052_RS11280	COG4771	TonB-dependent receptor
F3052_RS11285	COG0612	Peptidase, M16
F3052_RS11290	COG0076	glutamate decarboxylase activity
F3052_RS11295	COG0531	amino acid
F3052_RS11300	COG1649	PFAM Uncharacterised BCR, COG1649
F3052_RS11310	COG3706	GGDEF domain
F3052_RS11315	COG2199	diguanylate cyclase activity
F3052_RS11315	COG2200	EAL domain
F3052_RS11315	COG2202	Pas domain
F3052_RS11320	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
F3052_RS11325	COG0747	negative chemotaxis
F3052_RS11330	COG0601	transmembrane transport
F3052_RS11335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3052_RS11340	COG0444	Belongs to the ABC transporter superfamily
F3052_RS11345	COG4608	Belongs to the ABC transporter superfamily
F3052_RS11350	COG1764	response to oxidative stress
F3052_RS11370	COG1064	alcohol dehydrogenase
F3052_RS11375	COG3093	addiction module antidote protein HigA
F3052_RS11380	COG2864	formate dehydrogenase
F3052_RS11385	COG0437	4 iron, 4 sulfur cluster binding
F3052_RS11395	COG0697	spore germination
F3052_RS11400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F3052_RS11410	COG2223	nitrite transmembrane transporter activity
F3052_RS11415	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F3052_RS11420	COG1140	nitrate reductase beta subunit
F3052_RS11425	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F3052_RS11430	COG2181	nitrate reductase activity
F3052_RS11435	COG0384	phenazine biosynthesis protein PhzF
F3052_RS11440	COG2162	N-hydroxyarylamine O-acetyltransferase activity
F3052_RS11445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3052_RS11455	COG5433	transposase activity
F3052_RS11475	COG3209	COG3209 Rhs family protein
F3052_RS11490	COG0625	glutathione transferase activity
F3052_RS11495	COG1113	amino acid transport
F3052_RS11500	COG3391	amine dehydrogenase activity
F3052_RS11505	COG4772	TonB-dependent receptor
F3052_RS11510	COG1802	Transcriptional regulator
F3052_RS11515	COG2130	NADP-dependent
F3052_RS11520	COG1247	-acetyltransferase
F3052_RS11525	COG3238	Protein conserved in bacteria
F3052_RS11550	COG1177	transmembrane transport
F3052_RS11555	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3052_RS11560	COG3842	ATPase activity
F3052_RS11565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3052_RS11570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3052_RS11575	COG1598	PFAM Uncharacterised protein family UPF0150
F3052_RS11580	COG1724	mRNA binding
F3052_RS11590	COG0826	peptidase U32
F3052_RS11595	COG1396	sequence-specific DNA binding
F3052_RS11600	COG3135	benzoate transporter
F3052_RS11605	COG0675	Transposase, IS605 OrfB family
F3052_RS11620	COG0500	methyltransferase
F3052_RS11625	COG1275	C4-dicarboxylate transporter malic acid transport protein
F3052_RS11630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F3052_RS11635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3052_RS11640	COG2841	Protein conserved in bacteria
F3052_RS11650	COG5383	Protein conserved in bacteria
F3052_RS11655	COG0583	DNA-binding transcription factor activity
F3052_RS11660	COG0840	transmembrane signaling receptor activity
F3052_RS11675	COG3038	cytochrome b561
F3052_RS11685	COG1012	belongs to the aldehyde dehydrogenase family
F3052_RS11690	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F3052_RS11695	COG1643	Atp-dependent helicase
F3052_RS11705	COG2453	phosphatase
F3052_RS11705	COG0671	phosphoesterase, PA-phosphatase related
F3052_RS11710	COG2267	carboxylic ester hydrolase activity
F3052_RS11715	COG4589	Belongs to the CDS family
F3052_RS11720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3052_RS11730	COG0667	Aldo Keto reductase
F3052_RS11745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F3052_RS11750	COG3327	negative regulation of DNA-templated transcription, initiation
F3052_RS11755	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
F3052_RS11760	COG0183	Belongs to the thiolase family
F3052_RS11765	COG2050	protein possibly involved in aromatic compounds catabolism
F3052_RS11770	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3052_RS11775	COG1024	Enoyl-CoA hydratase
F3052_RS11780	COG1024	Enoyl-CoA hydratase
F3052_RS11785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3052_RS11790	COG2151	metal-sulfur cluster biosynthetic enzyme
F3052_RS11795	COG3396	Phenylacetate-CoA oxygenase
F3052_RS11800	COG3460	Phenylacetate-CoA oxygenase
F3052_RS11805	COG3396	Phenylacetate-CoA oxygenase
F3052_RS11810	COG1012	belongs to the aldehyde dehydrogenase family
F3052_RS11810	COG2030	dehydratase
F3052_RS11815	COG3733	amine oxidase
F3052_RS11820	COG1012	belongs to the aldehyde dehydrogenase family
F3052_RS11825	COG2207	Transcriptional regulator
F3052_RS11830	COG3784	Protein of unknown function (DUF1318)
F3052_RS11840	COG2911	Protein conserved in bacteria
F3052_RS11845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3052_RS11850	COG3187	Heat shock protein
F3052_RS11855	COG3042	response to heat
F3052_RS11860	COG0674	pyruvate-flavodoxin oxidoreductase activity
F3052_RS11860	COG1013	pyruvate-flavodoxin oxidoreductase activity
F3052_RS11860	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3052_RS11860	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
F3052_RS11865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F3052_RS11870	COG0589	response to stress
F3052_RS11880	COG0513	Belongs to the DEAD box helicase family
F3052_RS11890	COG3706	GGDEF domain
F3052_RS11895	COG2840	Smr protein MutS2
F3052_RS11900	COG0583	DNA-binding transcription factor activity
F3052_RS11905	COG1473	amidohydrolase
F3052_RS11910	COG1473	amidohydrolase
F3052_RS11915	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
F3052_RS11920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3052_RS11925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3052_RS11930	COG0589	response to stress
F3052_RS11935	COG3182	Iron-regulated membrane protein
F3052_RS11940	COG0668	transmembrane transport
F3052_RS11945	COG4166	transmembrane transport
F3052_RS11950	COG0583	DNA-binding transcription factor activity
F3052_RS11955	COG1073	alpha beta
F3052_RS11970	COG2866	Carboxypeptidase
F3052_RS11975	COG4948	Mandelate Racemase Muconate Lactonizing
F3052_RS11980	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F3052_RS11985	COG3283	Transcriptional regulator of aromatic amino acids metabolism
F3052_RS11995	COG3106	COG3106 Predicted ATPase
F3052_RS12000	COG1609	Transcriptional regulator
F3052_RS12010	COG3842	ATPase activity
F3052_RS12015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3052_RS12020	COG1554	hydrolase, family 65, central catalytic
F3052_RS12025	COG0673	inositol 2-dehydrogenase activity
F3052_RS12030	COG1082	Xylose isomerase domain protein TIM barrel
F3052_RS12035	COG1063	alcohol dehydrogenase
F3052_RS12040	COG0395	ABC-type sugar transport system, permease component
F3052_RS12045	COG1175	transmembrane transport
F3052_RS12050	COG1653	transport
F3052_RS12055	COG0366	Alpha amylase catalytic
F3052_RS12060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3052_RS12070	COG1983	PspC domain protein
F3052_RS12080	COG1842	Phage shock protein A
F3052_RS12085	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F3052_RS12090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3052_RS12095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3052_RS12100	COG1012	belongs to the aldehyde dehydrogenase family
F3052_RS12105	COG1396	sequence-specific DNA binding
F3052_RS12105	COG1917	Cupin 2, conserved barrel domain protein
F3052_RS12110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F3052_RS12115	COG0174	glutamine synthetase
F3052_RS12125	COG0531	amino acid
F3052_RS12135	COG4166	transmembrane transport
F3052_RS12140	COG4168	peptide transport system, permease
F3052_RS12145	COG4171	peptide transport system, permease
F3052_RS12150	COG4172	Belongs to the ABC transporter superfamily
F3052_RS12155	COG4172	Belongs to the ABC transporter superfamily
F3052_RS12160	COG2852	Protein conserved in bacteria
F3052_RS12165	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3052_RS12170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3052_RS12170	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3052_RS12185	COG5001	Diguanylate cyclase
F3052_RS12195	COG1349	DNA-binding transcription factor activity
F3052_RS12205	COG0023	Translation Initiation Factor
F3052_RS12215	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F3052_RS12220	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F3052_RS12225	COG0671	phosphoesterase, PA-phosphatase related
F3052_RS12235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3052_RS12255	COG0583	DNA-binding transcription factor activity
F3052_RS12260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3052_RS12270	COG0616	signal peptide processing
F3052_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS12280	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
F3052_RS12285	COG1187	pseudouridine synthase activity
F3052_RS12290	COG4907	membrane protein (DUF2207)
F3052_RS12295	COG0009	L-threonylcarbamoyladenylate synthase
F3052_RS12300	COG0613	PHP domain protein
F3052_RS12310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3052_RS12315	COG0512	Glutamine amidotransferase of anthranilate synthase
F3052_RS12315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F3052_RS12320	COG0135	phosphoribosylanthranilate isomerase activity
F3052_RS12320	COG0134	indole-3-glycerol-phosphate synthase activity
F3052_RS12335	COG3729	General stress protein
F3052_RS12340	COG3685	Protein conserved in bacteria
F3052_RS12345	COG3685	Protein conserved in bacteria
F3052_RS12350	COG3047	cAMP biosynthetic process
F3052_RS12370	COG1607	acyl-coa hydrolase
F3052_RS12375	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F3052_RS12380	COG2350	Protein conserved in bacteria
F3052_RS12385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3052_RS12405	COG4608	Belongs to the ABC transporter superfamily
F3052_RS12410	COG0444	Belongs to the ABC transporter superfamily
F3052_RS12415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3052_RS12420	COG0601	transmembrane transport
F3052_RS12425	COG4166	transmembrane transport
F3052_RS12435	COG2095	MarC family integral membrane protein
F3052_RS12440	COG1012	belongs to the aldehyde dehydrogenase family
F3052_RS12440	COG1454	alcohol dehydrogenase
F3052_RS12450	COG1435	thymidine kinase activity
F3052_RS12460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3052_RS12465	COG0745	RESPONSE REGULATOR receiver
F3052_RS12470	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3052_RS12480	COG0788	formyltetrahydrofolate deformylase activity
F3052_RS12505	COG2181	nitrate reductase activity
F3052_RS12510	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F3052_RS12515	COG1140	nitrate reductase beta subunit
F3052_RS12520	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F3052_RS12525	COG2223	nitrite transmembrane transporter activity
F3052_RS12530	COG3850	Histidine kinase
F3052_RS12535	COG2197	response regulator
F3052_RS12540	COG4932	domain protein
F3052_RS12545	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F3052_RS12550	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F3052_RS12555	COG4572	Cation transport regulator
F3052_RS12560	COG0387	Pfam Sodium calcium exchanger
F3052_RS12585	COG2912	Transglutaminase-like superfamily
F3052_RS12590	COG3094	Invasion gene expression up-regulator, SirB
F3052_RS12595	COG2890	protein-(glutamine-N5) methyltransferase activity
F3052_RS12620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F3052_RS12625	COG0659	secondary active sulfate transmembrane transporter activity
F3052_RS12640	COG0012	GTP binding
F3052_RS12650	COG3468	outer membrane autotransporter barrel domain protein
F3052_RS12655	COG3284	Transcriptional regulator
F3052_RS12660	COG2376	Dihydroxyacetone kinase
F3052_RS12665	COG1461	Dihydroxyacetone kinase
F3052_RS12670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3052_RS12670	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
F3052_RS12670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS12690	COG2261	transglycosylase associated protein
F3052_RS12695	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
F3052_RS12705	COG1619	proteins homologs of microcin C7 resistance protein MccF
F3052_RS12715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3052_RS12725	COG2719	SpoVR family
F3052_RS12740	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F3052_RS12745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3052_RS12750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3052_RS12765	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3052_RS12790	COG2894	cell division
F3052_RS12850	COG2200	EAL domain
F3052_RS12875	COG2200	EAL domain
F3052_RS12880	COG0789	Transcriptional regulator
F3052_RS12885	COG5562	phage envelope protein
F3052_RS12905	COG0538	isocitrate dehydrogenase activity
F3052_RS12910	COG1187	pseudouridine synthase activity
F3052_RS12930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3052_RS12935	COG0745	RESPONSE REGULATOR receiver
F3052_RS12940	COG2205	protein histidine kinase activity
F3052_RS12945	COG2850	peptidyl-arginine hydroxylation
F3052_RS12955	COG3842	ATPase activity
F3052_RS12965	COG1177	transmembrane transport
F3052_RS12970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3052_RS12980	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F3052_RS12990	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F3052_RS13000	COG4591	ABC-type transport system involved in lipoprotein release permease component
F3052_RS13005	COG1136	(ABC) transporter
F3052_RS13010	COG4591	ABC-type transport system involved in lipoprotein release permease component
F3052_RS13015	COG4763	Acyl-transferase
F3052_RS13020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F3052_RS13025	COG1376	ErfK ybiS ycfS ynhG family protein
F3052_RS13025	COG1388	LysM domain
F3052_RS13035	COG1309	transcriptional regulator
F3052_RS13040	COG3134	Outer membrane lipoprotein
F3052_RS13045	COG1252	NADH dehydrogenase
F3052_RS13065	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
F3052_RS13070	COG5633	Lipoprotein
F3052_RS13075	COG0537	adenosine 5'-monophosphoramidase activity
F3052_RS13080	COG4773	Receptor
F3052_RS13085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS13085	COG1263	PTS System
F3052_RS13090	COG0084	hydrolase, TatD family'
F3052_RS13095	COG0470	DNA polymerase III
F3052_RS13105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3052_RS13110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3052_RS13115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3052_RS13125	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS13130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F3052_RS13150	COG1399	metal-binding, possibly nucleic acid-binding protein
F3052_RS13155	COG0424	maF-like protein
F3052_RS13160	COG0564	pseudouridine synthase activity
F3052_RS13165	COG1530	ribonuclease E activity
F3052_RS13170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3052_RS13175	COG1256	bacterial-type flagellum assembly
F3052_RS13180	COG3951	Flagellar rod assembly protein muramidase FlgJ
F3052_RS13180	COG1705	Flagellar rod assembly protein muramidase FlgJ
F3052_RS13195	COG4786	Flagellar basal body rod
F3052_RS13200	COG4787	bacterial-type flagellum-dependent cell motility
F3052_RS13205	COG1749	Flagellar hook protein flgE
F3052_RS13210	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F3052_RS13215	COG1558	bacterial-type flagellum-dependent cell motility
F3052_RS13220	COG1815	bacterial-type flagellum-dependent cell motility
F3052_RS13225	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
F3052_RS13230	COG2747	anti-sigma28 factor FlgM
F3052_RS13235	COG3418	PFAM FlgN family protein
F3052_RS13240	COG0728	peptidoglycan biosynthetic process
F3052_RS13245	COG0673	inositol 2-dehydrogenase activity
F3052_RS13255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3052_RS13265	COG2999	glutathione oxidoreductase activity
F3052_RS13300	COG3038	cytochrome b561
F3052_RS13305	COG2353	YceI-like domain
F3052_RS13315	COG1560	Kdo2-lipid A biosynthetic process
F3052_RS13330	COG5645	(Lipo)protein
F3052_RS13335	COG2943	transferase activity, transferring hexosyl groups
F3052_RS13350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3052_RS13355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
F3052_RS13380	COG2197	response regulator
F3052_RS13395	COG1462	curli production assembly transport component CsgG
F3052_RS13405	COG3381	protein complex oligomerization
F3052_RS13440	COG3706	GGDEF domain
F3052_RS13445	COG0457	Tetratricopeptide repeat
F3052_RS13450	COG0726	polysaccharide deacetylase
F3052_RS13450	COG1649	PFAM Uncharacterised BCR, COG1649
F3052_RS13455	COG1215	transferase activity, transferring glycosyl groups
F3052_RS13460	COG3658	cytochrome
F3052_RS13465	COG1702	phosphate starvation-inducible protein PhoH
F3052_RS13470	COG2837	iron assimilation
F3052_RS13475	COG2822	iron ion transport
F3052_RS13485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3052_RS13495	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3052_RS13495	COG0506	proline dehydrogenase activity
F3052_RS13495	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3052_RS13500	COG1309	transcriptional regulator
F3052_RS13535	COG2233	PERMEase
F3052_RS13540	COG3729	General stress protein
F3052_RS13575	COG3381	protein complex oligomerization
F3052_RS13580	COG0243	molybdopterin cofactor binding
F3052_RS13585	COG3005	denitrification pathway
F3052_RS13590	COG0745	RESPONSE REGULATOR receiver
F3052_RS13595	COG1879	ABC-type sugar transport system periplasmic component
F3052_RS13600	COG2205	protein histidine kinase activity
F3052_RS13600	COG2198	Histidine kinase
F3052_RS13600	COG0784	Response regulator, receiver
F3052_RS13605	COG0348	domain, Protein
F3052_RS13625	COG1278	Cold shock
F3052_RS13630	COG1278	Cold shock
F3052_RS13650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3052_RS13655	COG1596	polysaccharide export
F3052_RS13660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3052_RS13665	COG3206	protein involved in exopolysaccharide biosynthesis
F3052_RS13665	COG0489	protein tyrosine kinase activity
F3052_RS13680	COG1294	oxidase, subunit
F3052_RS13685	COG1271	oxidase subunit
F3052_RS13690	COG1773	rubredoxin
F3052_RS13695	COG1999	signal sequence binding
F3052_RS13700	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F3052_RS13705	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
F3052_RS13710	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
F3052_RS13715	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
F3052_RS13730	COG5301	cellulose 1,4-beta-cellobiosidase activity
F3052_RS13760	COG1196	nuclear chromosome segregation
F3052_RS13810	COG1030	water channel activity
F3052_RS13830	COG4220	transposase activity
F3052_RS13895	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
F3052_RS13900	COG1403	HNH endonuclease
F3052_RS13955	COG1846	Transcriptional regulator
F3052_RS13965	COG4197	protein conserved in bacteria, prophage-related
F3052_RS13995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3052_RS14010	COG0670	Belongs to the BI1 family
F3052_RS14015	COG2920	part of a sulfur-relay system
F3052_RS14020	COG1254	Belongs to the acylphosphatase family
F3052_RS14035	COG1832	CoA-binding protein
F3052_RS14050	COG0210	DNA helicase
F3052_RS14055	COG3304	Inner membrane component domain
F3052_RS14060	COG1289	transmembrane transporter activity
F3052_RS14065	COG3070	regulator of competence-specific genes
F3052_RS14075	COG2885	chlorophyll binding
F3052_RS14075	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F3052_RS14085	COG1067	ATP-dependent peptidase activity
F3052_RS14095	COG3130	regulation of translation
F3052_RS14100	COG3009	Protein conserved in bacteria
F3052_RS14105	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F3052_RS14105	COG3008	intermembrane lipid transfer
F3052_RS14110	COG2995	paraquat-inducible protein a
F3052_RS14115	COG0488	(ABC) transporter
F3052_RS14125	COG3217	Mosc domain protein beta barrel domain protein
F3052_RS14125	COG0633	Ferredoxin
F3052_RS14140	COG3121	Chaperone
F3052_RS14145	COG3539	Fimbrial protein
F3052_RS14150	COG3539	Fimbrial protein
F3052_RS14155	COG3539	Fimbrial protein
F3052_RS14160	COG3188	usher protein
F3052_RS14165	COG3121	Chaperone
F3052_RS14170	COG3539	Fimbrial protein
F3052_RS14175	COG0431	NADPH-dependent FMN reductase
F3052_RS14180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3052_RS14190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3052_RS14195	COG1116	anion transmembrane transporter activity
F3052_RS14200	COG0308	aminopeptidase N
F3052_RS14220	COG1448	Aminotransferase
F3052_RS14225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3052_RS14230	COG3108	Peptidase M15
F3052_RS14235	COG2989	Protein conserved in bacteria
F3052_RS14245	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F3052_RS14255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3052_RS14260	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F3052_RS14265	COG3173	Aminoglycoside phosphotransferase
F3052_RS14280	COG3214	Protein conserved in bacteria
F3052_RS14285	COG1663	tetraacyldisaccharide 4'-kinase activity
F3052_RS14290	COG1132	(ABC) transporter
F3052_RS14295	COG0658	competence protein
F3052_RS14295	COG2333	competence protein COMEC
F3052_RS14305	COG0539	negative regulation of cytoplasmic translation
F3052_RS14315	COG0501	Belongs to the peptidase M48B family
F3052_RS14330	COG2323	membrane
F3052_RS14335	COG1944	ATP diphosphatase activity
F3052_RS14340	COG2116	formate transmembrane transporter activity
F3052_RS14345	COG1882	Formate acetyltransferase
F3052_RS14350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3052_RS14355	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3052_RS14360	COG0583	DNA-binding transcription factor activity
F3052_RS14365	COG0531	amino acid
F3052_RS14375	COG1335	isochorismatase
F3052_RS14380	COG3302	dmso reductase anchor subunit
F3052_RS14385	COG0437	4 iron, 4 sulfur cluster binding
F3052_RS14390	COG0243	molybdopterin cofactor binding
F3052_RS14400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F3052_RS14410	COG1674	ftsk spoiiie
F3052_RS14410	COG1178	ABC-type Fe3 transport system permease component
F3052_RS14415	COG1522	sequence-specific DNA binding
F3052_RS14420	COG0492	ferredoxin-NADP+ reductase activity
F3052_RS14425	COG4988	ABC transporter
F3052_RS14430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F3052_RS14450	COG0542	response to heat
F3052_RS14460	COG1278	Cold shock
F3052_RS14465	COG1136	(ABC) transporter
F3052_RS14465	COG0577	efflux transmembrane transporter activity
F3052_RS14470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3052_RS14475	COG2990	Protein conserved in bacteria
F3052_RS14480	COG3593	DNA synthesis involved in DNA repair
F3052_RS14490	COG2431	L-lysine efflux transmembrane transporter activity
F3052_RS14500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3052_RS14505	COG0028	Belongs to the TPP enzyme family
F3052_RS14510	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F3052_RS14515	COG0702	epimerase
F3052_RS14520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3052_RS14525	COG3023	N-Acetylmuramoyl-L-alanine amidase
F3052_RS14540	COG1126	abc transporter atp-binding protein
F3052_RS14545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3052_RS14550	COG4215	(ABC) transporter
F3052_RS14555	COG4160	amino acid transport
F3052_RS14560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3052_RS14575	COG1177	transmembrane transport
F3052_RS14580	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3052_RS14585	COG3842	ATPase activity
F3052_RS14590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3052_RS14605	COG0778	Nitroreductase
F3052_RS14615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3052_RS14670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3052_RS14685	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
F3052_RS14690	COG3385	transposase activity
F3052_RS14780	COG4695	Portal protein
F3052_RS14815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3052_RS14865	COG3226	Transcriptional regulator
F3052_RS14870	COG0738	Major facilitator superfamily
F3052_RS14875	COG0561	phosphatase activity
F3052_RS14895	COG2814	Major facilitator Superfamily
F3052_RS14900	COG0671	phosphoesterase, PA-phosphatase related
F3052_RS14905	COG1349	DNA-binding transcription factor activity
F3052_RS14910	COG1686	Belongs to the peptidase S11 family
F3052_RS14915	COG0625	glutathione transferase activity
F3052_RS14920	COG2133	pyrroloquinoline quinone binding
F3052_RS14935	COG2199	diguanylate cyclase activity
F3052_RS14940	COG2200	EAL domain
F3052_RS14945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3052_RS14955	COG0747	negative chemotaxis
F3052_RS14960	COG4172	Belongs to the ABC transporter superfamily
F3052_RS14965	COG1446	asparaginase
F3052_RS14970	COG0303	'Molybdopterin
F3052_RS14975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3052_RS14980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3052_RS14985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3052_RS14990	COG1882	Formate acetyltransferase
F3052_RS14995	COG0561	phosphatase activity
F3052_RS15005	COG0488	(ABC) transporter
F3052_RS15010	COG1376	ErfK ybiS ycfS ynhG family protein
F3052_RS15015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F3052_RS15020	COG1321	iron dependent repressor
F3052_RS15030	COG2194	sulfuric ester hydrolase activity
F3052_RS15035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F3052_RS15045	COG5006	permease, DMT superfamily
F3052_RS15055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3052_RS15060	COG0765	amino acid transport
F3052_RS15065	COG1126	abc transporter atp-binding protein
F3052_RS15070	COG0668	transmembrane transport
F3052_RS15085	COG4774	siderophore transport
F3052_RS15095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3052_RS15105	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3052_RS15110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F3052_RS15115	COG1199	ATP-dependent helicase activity
F3052_RS15120	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
F3052_RS15125	COG0513	Belongs to the DEAD box helicase family
F3052_RS15130	COG1309	transcriptional regulator
F3052_RS15140	COG1131	(ABC) transporter
F3052_RS15145	COG0842	Transport permease protein
F3052_RS15150	COG0842	Transport permease protein
F3052_RS15160	COG3568	Endonuclease Exonuclease Phosphatase
F3052_RS15165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3052_RS15170	COG0392	lysyltransferase activity
F3052_RS15175	COG0670	Belongs to the BI1 family
F3052_RS15180	COG0670	Belongs to the BI1 family
F3052_RS15185	COG0314	molybdopterin synthase activity
F3052_RS15190	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F3052_RS15200	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3052_RS15210	COG0391	Required for morphogenesis under gluconeogenic growth conditions
F3052_RS15220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F3052_RS15225	COG2226	methyltransferase
F3052_RS15240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3052_RS15245	COG1881	PFAM PEBP family protein
F3052_RS15250	COG4677	pectinesterase activity
F3052_RS15255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3052_RS15260	COG0471	metal ion transport
F3052_RS15265	COG2828	Protein conserved in bacteria
F3052_RS15270	COG0583	DNA-binding transcription factor activity
F3052_RS15280	COG0561	phosphatase activity
F3052_RS15285	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F3052_RS15290	COG4149	molybdate abc transporter
F3052_RS15295	COG0725	ABC transporter, periplasmic molybdate-binding protein
F3052_RS15305	COG3585	molybdate ion transport
F3052_RS15305	COG2005	Transcriptional regulator
F3052_RS15310	COG1119	ATPase activity
F3052_RS15315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3052_RS15320	COG1085	galactose-1-phosphate uridylyltransferase
F3052_RS15330	COG2017	converts alpha-aldose to the beta-anomer
F3052_RS15340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3052_RS15350	COG1230	cation diffusion facilitator family transporter
F3052_RS15355	COG3201	nicotinamide mononucleotide transporter
F3052_RS15405	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F3052_RS15410	COG2885	chlorophyll binding
F3052_RS15420	COG3064	Membrane
F3052_RS15425	COG0848	biopolymer transport protein
F3052_RS15430	COG0811	peptide transport
F3052_RS15435	COG0824	Thioesterase
F3052_RS15440	COG3790	cyd operon protein YbgE
F3052_RS15445	COG4890	Cyd operon protein YbgT
F3052_RS15450	COG1294	oxidase, subunit
F3052_RS15455	COG1271	oxidase subunit
F3052_RS15465	COG0383	alpha-mannosidase activity
F3052_RS15470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS15470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS15470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS15475	COG2188	Transcriptional regulator
F3052_RS15480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3052_RS15490	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3052_RS15495	COG0567	Dehydrogenase, E1 component
F3052_RS15500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F3052_RS15505	COG1053	succinate dehydrogenase
F3052_RS15510	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F3052_RS15515	COG2009	succinate dehydrogenase
F3052_RS15525	COG0372	Belongs to the citrate synthase family
F3052_RS15530	COG3539	Fimbrial protein
F3052_RS15535	COG3188	usher protein
F3052_RS15540	COG3121	Chaperone
F3052_RS15545	COG3539	Fimbrial protein
F3052_RS15550	COG3180	Ammonia monooxygenase
F3052_RS15565	COG1984	allophanate hydrolase subunit 2
F3052_RS15570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F3052_RS15575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F3052_RS15580	COG3104	oligopeptide transport
F3052_RS15585	COG0415	Belongs to the DNA photolyase family
F3052_RS15590	COG3272	Protein of unknown function (DUF1722)
F3052_RS15645	COG2205	protein histidine kinase activity
F3052_RS15650	COG0745	RESPONSE REGULATOR receiver
F3052_RS15660	COG1982	Orn Lys Arg decarboxylase major
F3052_RS15665	COG0531	amino acid
F3052_RS15685	COG0033	Phosphoglucomutase
F3052_RS15690	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
F3052_RS15695	COG0596	Alpha beta hydrolase
F3052_RS15705	COG0716	FMN binding
F3052_RS15715	COG0735	belongs to the Fur family
F3052_RS15735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS15735	COG2190	(PTS) system
F3052_RS15735	COG1263	PTS System
F3052_RS15745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3052_RS15750	COG1940	carbohydrate kinase activity
F3052_RS15750	COG1846	Transcriptional regulator
F3052_RS15755	COG0647	UMP catabolic process
F3052_RS15760	COG0367	asparagine synthase
F3052_RS15785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3052_RS15795	COG1702	phosphate starvation-inducible protein PhoH
F3052_RS15805	COG4535	Mg2 and Co2 transporter CorC
F3052_RS15810	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F3052_RS15815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3052_RS15820	COG0765	amino acid transport
F3052_RS15825	COG0765	amino acid transport
F3052_RS15830	COG1126	abc transporter atp-binding protein
F3052_RS15840	COG0443	Heat shock 70 kDa protein
F3052_RS15845	COG2214	Heat shock protein DnaJ domain protein
F3052_RS15855	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F3052_RS15860	COG2214	Heat shock protein DnaJ domain protein
F3052_RS15870	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F3052_RS15875	COG2888	peptidyl-tyrosine sulfation
F3052_RS15890	COG1466	dna polymerase III delta subunit
F3052_RS15900	COG0406	alpha-ribazole phosphatase activity
F3052_RS15905	COG0799	negative regulation of ribosome biogenesis
F3052_RS15915	COG0768	penicillin binding
F3052_RS15920	COG0772	Belongs to the SEDS family
F3052_RS15925	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3052_RS15930	COG1686	Belongs to the peptidase S11 family
F3052_RS15945	COG0583	DNA-binding transcription factor activity
F3052_RS15955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3052_RS15960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3052_RS15980	COG3069	C4-dicarboxylate transmembrane transporter activity
F3052_RS15985	COG4565	transcriptional regulatory protein
F3052_RS15990	COG3290	protein histidine kinase activity
F3052_RS15995	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
F3052_RS16005	COG2301	Belongs to the HpcH HpaI aldolase family
F3052_RS16010	COG3051	citrate lyase alpha subunit
F3052_RS16025	COG0471	metal ion transport
F3052_RS16030	COG3719	Belongs to the RNase T2 family
F3052_RS16035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3052_RS16040	COG1063	alcohol dehydrogenase
F3052_RS16045	COG0589	response to stress
F3052_RS16050	COG3634	alkyl hydroperoxide reductase activity
F3052_RS16055	COG0450	alkyl hydroperoxide reductase
F3052_RS16060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3052_RS16065	COG0583	DNA-binding transcription factor activity
F3052_RS16070	COG3969	phosphoadenosine phosphosulfate
F3052_RS16075	COG1475	DNA binding
F3052_RS16080	COG0436	Aminotransferase
F3052_RS16085	COG0371	Dehydrogenase
F3052_RS16090	COG2879	small protein
F3052_RS16095	COG1966	Carbon starvation protein
F3052_RS16100	COG2050	protein possibly involved in aromatic compounds catabolism
F3052_RS16105	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS16110	COG3433	isochorismatase activity
F3052_RS16110	COG1535	isochorismatase
F3052_RS16115	COG1021	2,3-dihydroxybenzoate-AMP ligase
F3052_RS16120	COG1169	isochorismate synthase
F3052_RS16125	COG4592	Periplasmic binding protein
F3052_RS16135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3052_RS16140	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3052_RS16145	COG1120	ATPase activity
F3052_RS16150	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
F3052_RS16155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3052_RS16155	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F3052_RS16160	COG3251	PFAM MbtH domain protein
F3052_RS16165	COG2382	esterase
F3052_RS16170	COG4771	TonB-dependent receptor
F3052_RS16175	COG2977	Belongs to the P-Pant transferase superfamily
F3052_RS16180	COG3385	transposase activity
F3052_RS16200	COG2315	Protein conserved in bacteria
F3052_RS16205	COG0778	Nitroreductase
F3052_RS16210	COG0668	transmembrane transport
F3052_RS16215	COG1113	amino acid transport
F3052_RS16220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3052_RS16225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3052_RS16230	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3052_RS16235	COG1538	Outer membrane efflux protein
F3052_RS16240	COG0745	RESPONSE REGULATOR receiver
F3052_RS16245	COG5002	protein histidine kinase activity
F3052_RS16250	COG1215	transferase activity, transferring glycosyl groups
F3052_RS16255	COG4783	chaperone-mediated protein folding
F3052_RS16265	COG2207	Transcriptional regulator
F3052_RS16270	COG4571	Outer membrane protease
F3052_RS16285	COG2076	Multidrug Resistance protein
F3052_RS16380	COG0582	viral genome integration into host DNA
F3052_RS16390	COG2197	response regulator
F3052_RS16395	COG3539	Fimbrial protein
F3052_RS16400	COG3539	Fimbrial protein
F3052_RS16420	COG3121	Chaperone
F3052_RS16425	COG3539	Fimbrial protein
F3052_RS16435	COG2501	S4 domain
F3052_RS16440	COG1988	membrane-bound metal-dependent
F3052_RS16450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F3052_RS16460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F3052_RS16465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3052_RS16470	COG0549	Belongs to the carbamate kinase family
F3052_RS16480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3052_RS16490	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3052_RS16495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3052_RS16500	COG3257	ureidoglycine aminohydrolase activity
F3052_RS16505	COG1929	Belongs to the glycerate kinase type-1 family
F3052_RS16510	COG2233	PERMEase
F3052_RS16520	COG1953	Uracil, thiamine, allantoin
F3052_RS16525	COG2084	Dehydrogenase
F3052_RS16530	COG3622	Belongs to the hyi family
F3052_RS16535	COG3960	tartronate-semialdehyde synthase activity
F3052_RS16540	COG1414	Transcriptional regulator
F3052_RS16550	COG0583	DNA-binding transcription factor activity
F3052_RS16575	COG3209	COG3209 Rhs family protein
F3052_RS16585	COG3209	COG3209 Rhs family protein
F3052_RS16590	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F3052_RS16595	COG4181	ATPase activity
F3052_RS16600	COG2755	lipolytic protein G-D-S-L family
F3052_RS16605	COG0300	oxidoreductase activity
F3052_RS16610	COG3118	belongs to the thioredoxin family
F3052_RS16615	COG0390	transport system, permease component
F3052_RS16620	COG4619	ABC transporter
F3052_RS16625	COG0330	HflC and HflK could
F3052_RS16630	COG1585	Membrane protein implicated in regulation of membrane protease activity
F3052_RS16635	COG0789	Transcriptional regulator
F3052_RS16640	COG0531	amino acid
F3052_RS16645	COG2066	Belongs to the glutaminase family
F3052_RS16650	COG2217	Heavy metal translocating P-type atpase
F3052_RS16655	COG3093	addiction module antidote protein HigA
F3052_RS16660	COG3735	TraB family
F3052_RS16665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3052_RS16670	COG0737	Belongs to the 5'-nucleotidase family
F3052_RS16675	COG2223	nitrite transmembrane transporter activity
F3052_RS16680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3052_RS16680	COG4651	solute:proton antiporter activity
F3052_RS16685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3052_RS16720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F3052_RS16730	COG2832	Protein of unknown function (DUF454)
F3052_RS16735	COG3923	Primosomal replication protein n
F3052_RS16745	COG1196	nuclear chromosome segregation
F3052_RS16745	COG3264	Mechanosensitive ion channel
F3052_RS16750	COG1309	transcriptional regulator
F3052_RS16755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3052_RS16760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3052_RS16775	COG0110	maltose O-acetyltransferase activity
F3052_RS16785	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F3052_RS16790	COG5507	3-demethylubiquinone-9 3-methyltransferase
F3052_RS16800	COG3695	enzyme binding
F3052_RS16805	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F3052_RS16810	COG1946	Acyl-CoA thioesterase
F3052_RS16815	COG0004	ammonium transporteR
F3052_RS16820	COG0347	Belongs to the P(II) protein family
F3052_RS16825	COG1132	(ABC) transporter
F3052_RS16830	COG1132	(ABC) transporter
F3052_RS16835	COG1522	sequence-specific DNA binding
F3052_RS16845	COG4533	DNA binding
F3052_RS16855	COG0824	Thioesterase
F3052_RS16860	COG1555	photosystem II stabilization
F3052_RS16865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3052_RS16870	COG0776	regulation of translation
F3052_RS16875	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3052_RS16895	COG0271	Belongs to the BolA IbaG family
F3052_RS16900	COG3056	Lipoprotein
F3052_RS16905	COG2223	nitrite transmembrane transporter activity
F3052_RS16910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3052_RS16915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3052_RS16920	COG1845	cytochrome c oxidase, subunit III
F3052_RS16925	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F3052_RS16935	COG2814	Major facilitator Superfamily
F3052_RS16945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F3052_RS16950	COG0693	protein deglycase activity
F3052_RS16965	COG0142	geranyltranstransferase activity
F3052_RS16975	COG0667	Aldo Keto reductase
F3052_RS16980	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F3052_RS16985	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F3052_RS17000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3052_RS17000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3052_RS17010	COG4238	major outer membrane lipoprotein
F3052_RS17015	COG3248	Nucleoside-binding outer membrane protein
F3052_RS17020	COG1403	HNH endonuclease
F3052_RS17025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F3052_RS17030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F3052_RS17035	COG1862	Preprotein translocase
F3052_RS17055	COG0366	Alpha amylase catalytic
F3052_RS17060	COG1113	amino acid transport
F3052_RS17065	COG1114	Component of the transport system for branched-chain amino acids
F3052_RS17070	COG5002	protein histidine kinase activity
F3052_RS17075	COG0745	RESPONSE REGULATOR receiver
F3052_RS17080	COG0420	3'-5' exonuclease activity
F3052_RS17085	COG0419	ATPase involved in DNA repair
F3052_RS17090	COG2814	Major facilitator Superfamily
F3052_RS17095	COG1940	carbohydrate kinase activity
F3052_RS17120	COG4126	flavin adenine dinucleotide binding
F3052_RS17140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3052_RS17145	COG3706	GGDEF domain
F3052_RS17155	COG1785	Belongs to the alkaline phosphatase family
F3052_RS17170	COG1181	Belongs to the D-alanine--D-alanine ligase family
F3052_RS17190	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F3052_RS17195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3052_RS17215	COG3468	outer membrane autotransporter barrel domain protein
F3052_RS17220	COG0113	porphobilinogen synthase activity
F3052_RS17225	COG2175	clavaminate synthase activity
F3052_RS17230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3052_RS17240	COG4521	taurine ABC transporter
F3052_RS17245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F3052_RS17250	COG1215	transferase activity, transferring glycosyl groups
F3052_RS17280	COG3122	Protein conserved in bacteria
F3052_RS17285	COG2814	Major facilitator Superfamily
F3052_RS17300	COG3971	2-oxopent-4-enoate hydratase activity
F3052_RS17320	COG1414	Transcriptional regulator
F3052_RS17325	COG1609	Transcriptional regulator
F3052_RS17330	COG3250	beta-galactosidase activity
F3052_RS17335	COG2223	nitrite transmembrane transporter activity
F3052_RS17340	COG0110	maltose O-acetyltransferase activity
F3052_RS17345	COG2807	transmembrane transport
F3052_RS17355	COG0288	reversible hydration of carbon dioxide
F3052_RS17360	COG0583	DNA-binding transcription factor activity
F3052_RS17365	COG0402	S-adenosylhomocysteine deaminase activity
F3052_RS17370	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F3052_RS17375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3052_RS17380	COG2079	MmgE PrpD family protein
F3052_RS17385	COG0372	Belongs to the citrate synthase family
F3052_RS17390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
F3052_RS17395	COG3829	transcription factor binding
F3052_RS17405	COG1280	lysine exporter protein (LysE YggA)
F3052_RS17420	COG1064	alcohol dehydrogenase
F3052_RS17425	COG0402	S-adenosylhomocysteine deaminase activity
F3052_RS17430	COG0549	Belongs to the carbamate kinase family
F3052_RS17440	COG1304	FMN binding
F3052_RS17445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3052_RS17455	COG0666	response to abiotic stimulus
F3052_RS17465	COG0583	DNA-binding transcription factor activity
F3052_RS17470	COG2771	luxR family
F3052_RS17470	COG2200	EAL domain
F3052_RS17480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3052_RS17505	COG1556	Lactate utilization protein
F3052_RS17510	COG1139	Iron-sulfur cluster binding protein
F3052_RS17515	COG0247	lactate metabolic process
F3052_RS17520	COG2207	Transcriptional regulator
F3052_RS17525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3052_RS17535	COG3059	membrane
F3052_RS17545	COG3708	Transcriptional regulator
F3052_RS17545	COG2207	Transcriptional regulator
F3052_RS17555	COG1388	LysM domain
F3052_RS17595	COG3188	usher protein
F3052_RS17605	COG3121	Chaperone
F3052_RS17610	COG0727	PFAM Uncharacterised protein family (UPF0153)
F3052_RS17615	COG3477	response to acidic pH
F3052_RS17620	COG2080	2 iron, 2 sulfur cluster binding
F3052_RS17625	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3052_RS17630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3052_RS17635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F3052_RS17640	COG0583	DNA-binding transcription factor activity
F3052_RS17690	COG1278	Cold shock
F3052_RS17695	COG0582	viral genome integration into host DNA
F3052_RS17805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F3052_RS17825	COG2195	Cleaves the N-terminal amino acid of tripeptides
F3052_RS17840	COG0454	-acetyltransferase
F3052_RS17850	COG2161	toxin-antitoxin pair type II binding
F3052_RS17870	COG1943	Transposase
F3052_RS17890	COG3077	Addiction module antitoxin, RelB DinJ family
F3052_RS17895	COG3041	Addiction module toxin RelE StbE family
F3052_RS17900	COG3034	peptidoglycan biosynthetic process
F3052_RS17905	COG0121	glutamine amidotransferase
F3052_RS17915	COG1960	acyl-CoA dehydrogenase activity
F3052_RS17925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3052_RS17930	COG5433	transposase activity
F3052_RS17940	COG3209	COG3209 Rhs family protein
F3052_RS18040	COG4104	PAAR repeat-containing protein
F3052_RS18060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3052_RS18070	COG2226	methyltransferase
F3052_RS18080	COG0741	lytic transglycosylase activity
F3052_RS18080	COG1388	LysM domain
F3052_RS18095	COG0583	DNA-binding transcription factor activity
F3052_RS18100	COG0656	L-ascorbic acid biosynthetic process
F3052_RS18135	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F3052_RS18140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F3052_RS18145	COG2011	ABC-type metal ion transport system permease component
F3052_RS18150	COG1464	Belongs to the NlpA lipoprotein family
F3052_RS18160	COG1720	tRNA m6t6A37 methyltransferase activity
F3052_RS18170	COG0791	NLP P60 protein
F3052_RS18175	COG3015	lipoprotein NlpE involved in copper resistance
F3052_RS18180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F3052_RS18185	COG4681	YaeQ
F3052_RS18195	COG4568	rho-dependent transcription termination
F3052_RS18200	COG0037	tRNA processing
F3052_RS18205	COG0346	lactoylglutathione lyase activity
F3052_RS18210	COG1982	Orn Lys Arg decarboxylase major
F3052_RS18220	COG0587	DNA-directed DNA polymerase activity
F3052_RS18245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3052_RS18250	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
F3052_RS18260	COG0750	zinc metalloprotease
F3052_RS18265	COG0575	Belongs to the CDS family
F3052_RS18270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F3052_RS18275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F3052_RS18300	COG0024	Methionine aminopeptidase
F3052_RS18315	COG1408	metallophosphoesterase
F3052_RS18325	COG3835	regulator
F3052_RS18330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3052_RS18345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3052_RS18350	COG2860	membrane
F3052_RS18375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3052_RS18380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3052_RS18385	COG1120	ATPase activity
F3052_RS18390	COG4774	siderophore transport
F3052_RS18395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3052_RS18400	COG1643	Atp-dependent helicase
F3052_RS18405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F3052_RS18415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3052_RS18425	COG0617	tRNA 3'-terminal CCA addition
F3052_RS18430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F3052_RS18435	COG3539	Fimbrial protein
F3052_RS18440	COG3121	Chaperone
F3052_RS18445	COG3188	usher protein
F3052_RS18450	COG3539	Fimbrial protein
F3052_RS18455	COG3539	Fimbrial protein
F3052_RS18460	COG3539	Fimbrial protein
F3052_RS18465	COG3539	Fimbrial protein
F3052_RS18480	COG5464	transposase or invertase
F3052_RS18490	COG0726	polysaccharide deacetylase
F3052_RS18495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS18500	COG0842	Transport permease protein
F3052_RS18505	COG1131	(ABC) transporter
F3052_RS18510	COG0288	reversible hydration of carbon dioxide
F3052_RS18515	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
F3052_RS18520	COG4993	Dehydrogenase
F3052_RS18525	COG2132	Multicopper oxidase
F3052_RS18550	COG1049	propionate catabolic process, 2-methylcitrate cycle
F3052_RS18555	COG3064	Membrane
F3052_RS18560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3052_RS18565	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3052_RS18570	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F3052_RS18575	COG2186	Transcriptional regulator
F3052_RS18580	COG1113	amino acid transport
F3052_RS18585	COG3725	Membrane protein required for beta-lactamase induction
F3052_RS18590	COG3023	N-Acetylmuramoyl-L-alanine amidase
F3052_RS18595	COG0157	Belongs to the NadC ModD family
F3052_RS18600	COG4969	Belongs to the N-Me-Phe pilin family
F3052_RS18605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3052_RS18610	COG1459	type II secretion system
F3052_RS18625	COG0237	dephospho-CoA kinase activity
F3052_RS18640	COG0494	nUDIX hydrolase
F3052_RS18660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3052_RS18665	COG0849	cell division
F3052_RS18670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F3052_RS18675	COG1181	Belongs to the D-alanine--D-alanine ligase family
F3052_RS18690	COG0772	Belongs to the SEDS family
F3052_RS18695	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F3052_RS18705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F3052_RS18710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F3052_RS18715	COG0768	penicillin binding
F3052_RS18720	COG3116	cell division
F3052_RS18730	COG2001	Belongs to the MraZ family
F3052_RS18735	COG1609	Transcriptional regulator
F3052_RS18745	COG0440	acetolactate synthase activity
F3052_RS18750	COG0028	Belongs to the TPP enzyme family
F3052_RS18760	COG0583	DNA-binding transcription factor activity
F3052_RS18775	COG0473	3-isopropylmalate dehydrogenase activity
F3052_RS18790	COG2814	Major facilitator Superfamily
F3052_RS18800	COG4533	DNA binding
F3052_RS18805	COG4143	(ABC) transporter
F3052_RS18810	COG1178	ABC-type Fe3 transport system permease component
F3052_RS18815	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F3052_RS18820	COG0586	Pfam SNARE associated Golgi protein
F3052_RS18825	COG4977	sequence-specific DNA binding
F3052_RS18830	COG1069	ribulokinase activity
F3052_RS18835	COG2160	L-arabinose isomerase activity
F3052_RS18840	COG0235	Class ii aldolase
F3052_RS18845	COG0417	DNA replication proofreading
F3052_RS18855	COG0564	pseudouridine synthase activity
F3052_RS18875	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F3052_RS18880	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F3052_RS18885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3052_RS18910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F3052_RS18925	COG2271	Major facilitator Superfamily
F3052_RS18930	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F3052_RS18935	COG0644	oxidoreductase
F3052_RS18985	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F3052_RS18990	COG0505	Belongs to the CarA family
F3052_RS19010	COG1047	Peptidyl-prolyl cis-trans
F3052_RS19025	COG0196	riboflavin kinase activity
F3052_RS19050	COG0583	DNA-binding transcription factor activity
F3052_RS19065	COG3385	transposase activity
F3052_RS19085	COG4735	regulation of single-species biofilm formation
F3052_RS19090	COG1584	GPR1 FUN34 yaaH family protein
F3052_RS19095	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3052_RS19100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3052_RS19105	COG1115	amino acid carrier protein
F3052_RS19120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F3052_RS19130	COG0527	aspartate kinase activity
F3052_RS19130	COG0460	homoserine dehydrogenase
F3052_RS19140	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F3052_RS19150	COG0745	RESPONSE REGULATOR receiver
F3052_RS19155	COG4452	Inner membrane protein CreD
F3052_RS19160	COG2205	protein histidine kinase activity
F3052_RS19165	COG0745	RESPONSE REGULATOR receiver
F3052_RS19170	COG3045	CreA protein
F3052_RS19175	COG3708	Transcriptional regulator
F3052_RS19175	COG2207	Transcriptional regulator
F3052_RS19195	COG0741	lytic transglycosylase activity
F3052_RS19200	COG0488	(ABC) transporter
F3052_RS19210	COG3172	ATPase kinase involved in NAD metabolism
F3052_RS19210	COG1056	cytidyltransferase-related domain
F3052_RS19215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F3052_RS19220	COG0560	Phosphoserine phosphatase
F3052_RS19225	COG3726	membrane protein affecting hemolysin expression
F3052_RS19235	COG3550	peptidyl-serine autophosphorylation
F3052_RS19260	COG1328	CTP reductase activity
F3052_RS19265	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3052_RS19270	COG0084	hydrolase, TatD family'
F3052_RS19275	COG4667	esterase of the alpha-beta hydrolase superfamily
F3052_RS19285	COG2823	Periplasmic or secreted lipoprotein
F3052_RS19295	COG1011	Hydrolase
F3052_RS19300	COG0456	acetyltransferase
F3052_RS19305	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
F3052_RS19325	COG4114	ferric iron reductase
F3052_RS19330	COG2197	response regulator
F3052_RS19335	COG2197	response regulator
F3052_RS19340	COG2966	Psort location CytoplasmicMembrane, score
F3052_RS19355	COG1484	DNA-dependent DNA replication
F3052_RS19370	COG1063	alcohol dehydrogenase
F3052_RS19375	COG1802	Transcriptional regulator
F3052_RS19380	COG2271	Major facilitator Superfamily
F3052_RS19385	COG0840	transmembrane signaling receptor activity
F3052_RS19390	COG1966	Carbon starvation protein
F3052_RS19395	COG2879	small protein
F3052_RS19400	COG0523	cobalamin synthesis protein
F3052_RS19420	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F3052_RS19430	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F3052_RS19440	COG5457	Domain of unknown function (DUF1127)
F3052_RS19445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3052_RS19460	COG2814	Major facilitator Superfamily
F3052_RS19465	COG2733	membrane
F3052_RS19470	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
F3052_RS19475	COG1924	4 iron, 4 sulfur cluster binding
F3052_RS19490	COG3204	pilus organization
F3052_RS19495	COG0477	Major facilitator Superfamily
F3052_RS19520	COG3366	ferrous iron transmembrane transporter activity
F3052_RS19525	COG0700	Nucleoside recognition
F3052_RS19530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3052_RS19535	COG0583	DNA-binding transcription factor activity
F3052_RS19555	COG2186	Transcriptional regulator
F3052_RS19560	COG0246	Mannitol dehydrogenase
F3052_RS19570	COG2610	gluconate transmembrane transporter activity
F3052_RS19575	COG3539	Fimbrial protein
F3052_RS19580	COG3539	Fimbrial protein
F3052_RS19585	COG3539	Fimbrial protein
F3052_RS19590	COG3188	usher protein
F3052_RS19595	COG3121	Chaperone
F3052_RS19600	COG3539	Fimbrial protein
F3052_RS19610	COG4974	Belongs to the 'phage' integrase family
F3052_RS19615	COG0582	viral genome integration into host DNA
F3052_RS19620	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F3052_RS19635	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
F3052_RS19635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3052_RS19650	COG3153	acetyltransferase
F3052_RS19655	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F3052_RS19665	COG1363	Peptidase, m42
F3052_RS19670	COG3414	Phosphotransferase system galactitol-specific IIB component
F3052_RS19675	COG3775	system Galactitol-specific IIC component
F3052_RS19680	COG0434	BtpA family
F3052_RS19685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS19690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3052_RS19695	COG1349	DNA-binding transcription factor activity
F3052_RS19700	COG1414	Transcriptional regulator
F3052_RS19705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3052_RS19710	COG0129	dihydroxy-acid dehydratase activity
F3052_RS19730	COG2390	Transcriptional regulator
F3052_RS19785	COG1484	DNA-dependent DNA replication
F3052_RS19795	COG2003	Belongs to the UPF0758 family
F3052_RS19815	COG3468	outer membrane autotransporter barrel domain protein
F3052_RS19855	COG3436	PFAM IS66 Orf2 family protein
F3052_RS19860	COG4372	Transposase
F3052_RS19890	COG3436	PFAM IS66 Orf2 family protein
F3052_RS19930	COG1595	DNA-templated transcription, initiation
F3052_RS19935	COG3712	iron ion homeostasis
F3052_RS19940	COG4772	TonB-dependent receptor
F3052_RS19945	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
F3052_RS19950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3052_RS19955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3052_RS19960	COG1120	ATPase activity
F3052_RS19965	COG2085	NADP oxidoreductase coenzyme F420-dependent
F3052_RS19975	COG2826	transposase and inactivated derivatives, IS30 family
F3052_RS20035	COG0464	growth
F3052_RS20040	COG1404	Belongs to the peptidase S8 family
F3052_RS20045	COG0582	viral genome integration into host DNA
F3052_RS20055	COG1064	alcohol dehydrogenase
F3052_RS20060	COG0433	COG0433 Predicted ATPase
F3052_RS20065	COG0795	lipopolysaccharide-transporting ATPase activity
F3052_RS20070	COG0795	lipopolysaccharide-transporting ATPase activity
F3052_RS20080	COG2927	DNA polymerase III (CHI subunit)
F3052_RS20090	COG4269	membrane
F3052_RS20095	COG0456	acetyltransferase
F3052_RS20100	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
F3052_RS20120	COG2731	YhcH YjgK YiaL family protein
F3052_RS20125	COG1309	transcriptional regulator
F3052_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS20135	COG0251	oxidation-reduction process
F3052_RS20155	COG0251	oxidation-reduction process
F3052_RS20160	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F3052_RS20170	COG1609	Transcriptional regulator
F3052_RS20175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS20175	COG1263	PTS System
F3052_RS20180	COG0366	Alpha amylase catalytic
F3052_RS20185	COG1328	CTP reductase activity
F3052_RS20190	COG0602	queuosine metabolic process
F3052_RS20195	COG3783	Cytochrome b(562)
F3052_RS20200	COG0312	modulator of DNA gyrase
F3052_RS20210	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F3052_RS20220	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3052_RS20225	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3052_RS20230	COG1129	ABC transporter
F3052_RS20235	COG1879	ABC-type sugar transport system periplasmic component
F3052_RS20240	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F3052_RS20245	COG2105	PFAM AIG2 family protein
F3052_RS20250	COG2911	Protein conserved in bacteria
F3052_RS20255	COG0729	surface antigen
F3052_RS20265	COG1253	flavin adenine dinucleotide binding
F3052_RS20275	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F3052_RS20280	COG1218	3'(2'),5'-bisphosphate nucleotidase
F3052_RS20285	COG0737	Belongs to the 5'-nucleotidase family
F3052_RS20290	COG1733	regulation of RNA biosynthetic process
F3052_RS20295	COG0702	epimerase
F3052_RS20300	COG0697	spore germination
F3052_RS20310	COG1113	amino acid transport
F3052_RS20315	COG0545	Peptidyl-prolyl cis-trans isomerase
F3052_RS20320	COG3061	Opacity-associated protein A
F3052_RS20325	COG1309	transcriptional regulator
F3052_RS20330	COG1028	Short-chain dehydrogenase reductase Sdr
F3052_RS20340	COG1024	Enoyl-CoA hydratase
F3052_RS20345	COG4670	ketone body catabolic process
F3052_RS20350	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F3052_RS20355	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F3052_RS20385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F3052_RS20425	COG3414	Phosphotransferase system galactitol-specific IIB component
F3052_RS20430	COG3037	sugar-specific permease SgaT UlaA
F3052_RS20445	COG1073	alpha beta
F3052_RS20450	COG3650	response to hydrogen peroxide
F3052_RS20460	COG1960	acyl-CoA dehydrogenase activity
F3052_RS20465	COG0754	glutathionylspermidine amidase activity
F3052_RS20470	COG5463	Belongs to the UPF0441 family
F3052_RS20475	COG3766	membrane
F3052_RS20485	COG1842	Phage shock protein A
F3052_RS20490	COG3789	protein conserved in bacteria
F3052_RS20495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3052_RS20500	COG0557	exoribonuclease II activity
F3052_RS20515	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F3052_RS20520	COG0330	HflC and HflK could
F3052_RS20525	COG0330	HflC and HflK could
F3052_RS20530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3052_RS20550	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3052_RS20555	COG0802	atpase or kinase
F3052_RS20560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F3052_RS20560	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F3052_RS20565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F3052_RS20605	COG3264	Mechanosensitive ion channel
F3052_RS20605	COG1511	domain protein
F3052_RS20620	COG0531	amino acid
F3052_RS20630	COG1053	succinate dehydrogenase
F3052_RS20635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F3052_RS20650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3052_RS20655	COG3040	lipid binding
F3052_RS20660	COG2076	Multidrug Resistance protein
F3052_RS20665	COG5510	response to toxic substance
F3052_RS20670	COG5510	response to toxic substance
F3052_RS20680	COG1509	lysine 2,3-aminomutase activity
F3052_RS20705	COG0531	amino acid
F3052_RS20710	COG3030	protein affecting phage T7 exclusion by the F plasmid
F3052_RS20715	COG1027	Aspartate ammonia-lyase
F3052_RS20720	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F3052_RS20730	COG4232	protein-disulfide reductase activity
F3052_RS20735	COG1309	transcriptional regulator
F3052_RS20745	COG3710	Transcriptional regulator
F3052_RS20750	COG0531	amino acid
F3052_RS20755	COG1982	Orn Lys Arg decarboxylase major
F3052_RS20760	COG3104	oligopeptide transport
F3052_RS20765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F3052_RS20780	COG2388	GCN5-related N-acetyl-transferase
F3052_RS20785	COG3592	Divergent 4Fe-4S mono-cluster
F3052_RS20790	COG3290	protein histidine kinase activity
F3052_RS20795	COG4565	transcriptional regulatory protein
F3052_RS20800	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F3052_RS20805	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F3052_RS20805	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F3052_RS20810	COG3647	Membrane
F3052_RS20815	COG2211	Major facilitator Superfamily
F3052_RS20820	COG1486	melibiose metabolic process
F3052_RS20825	COG2169	Transcriptional regulator
F3052_RS20830	COG1982	Orn Lys Arg decarboxylase major
F3052_RS20835	COG2207	Transcriptional regulator
F3052_RS20840	COG0531	amino acid
F3052_RS20845	COG2194	sulfuric ester hydrolase activity
F3052_RS20850	COG0745	RESPONSE REGULATOR receiver
F3052_RS20855	COG0642	Histidine kinase
F3052_RS20865	COG0477	Major facilitator Superfamily
F3052_RS20880	COG2824	Alkylphosphonate utilization operon protein PhnA
F3052_RS20885	COG2764	glyoxalase bleomycin resistance protein dioxygenase
F3052_RS20890	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F3052_RS20895	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F3052_RS20905	COG2188	Transcriptional regulator
F3052_RS20910	COG3624	Phosphonate C-P lyase system protein PhnG
F3052_RS20915	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F3052_RS20920	COG3626	phosphonate metabolism
F3052_RS20925	COG3627	carbon phosphorus lyase activity
F3052_RS20930	COG4107	phosphonate C-P lyase system protein PhnK
F3052_RS20935	COG4778	phosphonate C-P lyase system protein PhnL
F3052_RS20940	COG3454	Phosphonate metabolism
F3052_RS20945	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3052_RS20950	COG0456	acetyltransferase
F3052_RS20955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F3052_RS20965	COG0698	ribose 5-phosphate isomerase
F3052_RS20970	COG1737	Transcriptional regulator
F3052_RS20975	COG1879	ABC-type sugar transport system periplasmic component
F3052_RS20980	COG1129	ABC transporter
F3052_RS20985	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3052_RS20990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3052_RS20995	COG1940	carbohydrate kinase activity
F3052_RS21000	COG2015	COG2015, Alkyl sulfatase and related hydrolases
F3052_RS21010	COG1566	PFAM secretion protein HlyD family protein
F3052_RS21015	COG1289	transmembrane transporter activity
F3052_RS21020	COG1538	Outer membrane efflux protein
F3052_RS21030	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F3052_RS21035	COG1301	dicarboxylic acid transport
F3052_RS21040	COG4235	cytochrome complex assembly
F3052_RS21045	COG3088	subunit of a heme lyase
F3052_RS21050	COG1138	Cytochrome C-type biogenesis protein
F3052_RS21055	COG3301	Polysulphide reductase, NrfD
F3052_RS21060	COG0437	4 iron, 4 sulfur cluster binding
F3052_RS21065	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
F3052_RS21075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3052_RS21080	COG3162	membrane
F3052_RS21090	COG1357	PFAM Pentapeptide repeats (8 copies)
F3052_RS21095	COG0025	NhaP-type Na H and K H
F3052_RS21100	COG2252	PERMEase
F3052_RS21105	COG0789	Transcriptional regulator
F3052_RS21110	COG2207	Transcriptional regulator
F3052_RS21115	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F3052_RS21125	COG0629	single-stranded DNA binding
F3052_RS21130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3052_RS21135	COG2315	Protein conserved in bacteria
F3052_RS21140	COG0432	Pfam Uncharacterised protein family UPF0047
F3052_RS21145	COG3700	Belongs to the class B bacterial acid phosphatase family
F3052_RS21155	COG1448	Aminotransferase
F3052_RS21160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3052_RS21165	COG0305	Participates in initiation and elongation during chromosome replication
F3052_RS21170	COG0604	alcohol dehydrogenase
F3052_RS21180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3052_RS21190	COG0735	belongs to the Fur family
F3052_RS21195	COG3237	CsbD-like
F3052_RS21200	COG0534	Mate efflux family protein
F3052_RS21210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F3052_RS21230	COG1357	PFAM Pentapeptide repeats (8 copies)
F3052_RS21245	COG3842	ATPase activity
F3052_RS21250	COG2182	Extracellular solute-binding protein
F3052_RS21255	COG1175	transmembrane transport
F3052_RS21260	COG3833	ABC-type maltose transport systems, permease component
F3052_RS21265	COG2814	Major facilitator Superfamily
F3052_RS21265	COG0477	Major facilitator Superfamily
F3052_RS21285	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3052_RS21310	COG0527	aspartate kinase activity
F3052_RS21320	COG1187	pseudouridine synthase activity
F3052_RS21330	COG1283	sodium-dependent phosphate transmembrane transporter activity
F3052_RS21335	COG0646	methionine synthase
F3052_RS21335	COG1410	methionine synthase
F3052_RS21340	COG1414	Transcriptional regulator
F3052_RS21355	COG2224	Isocitrate lyase
F3052_RS21360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F3052_RS21370	COG0456	acetyltransferase
F3052_RS21405	COG0151	Belongs to the GarS family
F3052_RS21410	COG2204	response regulator
F3052_RS21415	COG4191	Histidine kinase
F3052_RS21420	COG3678	ATP-independent chaperone mediated protein folding
F3052_RS21435	COG3068	Protein conserved in bacteria
F3052_RS21470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3052_RS21475	COG2104	thiamine diphosphate biosynthetic process
F3052_RS21485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F3052_RS21525	COG0250	Participates in transcription elongation, termination and antitermination
F3052_RS21530	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3052_RS21565	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
F3052_RS21565	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
F3052_RS21570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F3052_RS21600	COG4206	TonB-dependent receptor
F3052_RS21615	COG1309	transcriptional regulator
F3052_RS21625	COG0583	DNA-binding transcription factor activity
F3052_RS21640	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F3052_RS21655	COG2194	sulfuric ester hydrolase activity
F3052_RS21660	COG2207	Transcriptional regulator
F3052_RS21665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS21670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3052_RS21675	COG1882	Formate acetyltransferase
F3052_RS21680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS21685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS21690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3052_RS21690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS21690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS21695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3052_RS21700	COG0371	Dehydrogenase
F3052_RS21705	COG3738	Protein conserved in bacteria
F3052_RS21710	COG0697	spore germination
F3052_RS21720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F3052_RS21725	COG0527	aspartate kinase activity
F3052_RS21725	COG0460	homoserine dehydrogenase
F3052_RS21730	COG0626	cystathionine gamma-synthase activity
F3052_RS21740	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F3052_RS21750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F3052_RS21755	COG1609	Transcriptional regulator
F3052_RS21760	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3052_RS21775	COG1575	Belongs to the MenA family. Type 1 subfamily
F3052_RS21790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F3052_RS21800	COG1494	fructose-1,6-bisphosphatase
F3052_RS21805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3052_RS21810	COG0589	response to stress
F3052_RS21815	COG3691	Protein conserved in bacteria
F3052_RS21820	COG3152	Membrane
F3052_RS21840	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F3052_RS21855	COG3678	ATP-independent chaperone mediated protein folding
F3052_RS21860	COG0745	RESPONSE REGULATOR receiver
F3052_RS21865	COG2205	protein histidine kinase activity
F3052_RS21870	COG2258	MOSC domain
F3052_RS21880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3052_RS21920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS21925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS21925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3052_RS21930	COG1363	Peptidase, m42
F3052_RS21935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3052_RS21935	COG3711	transcriptional antiterminator
F3052_RS21955	COG0437	4 iron, 4 sulfur cluster binding
F3052_RS21960	COG2864	formate dehydrogenase
F3052_RS21970	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3052_RS21975	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3052_RS21980	COG0456	acetyltransferase
F3052_RS21995	COG1011	Hydrolase
F3052_RS22000	COG1349	DNA-binding transcription factor activity
F3052_RS22005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3052_RS22010	COG2084	Dehydrogenase
F3052_RS22015	COG3684	Belongs to the aldolase LacD family
F3052_RS22020	COG2942	2-epimerase
F3052_RS22025	COG2017	converts alpha-aldose to the beta-anomer
F3052_RS22035	COG1501	Belongs to the glycosyl hydrolase 31 family
F3052_RS22040	COG2211	Major facilitator Superfamily
F3052_RS22045	COG2211	Major facilitator Superfamily
F3052_RS22050	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F3052_RS22055	COG2271	Major facilitator Superfamily
F3052_RS22060	COG1082	Xylose isomerase domain protein TIM barrel
F3052_RS22065	COG2188	Transcriptional regulator
F3052_RS22070	COG1217	gtp-binding protein TYPA
F3052_RS22075	COG0174	glutamine synthetase
F3052_RS22080	COG3852	Histidine kinase
F3052_RS22085	COG2204	response regulator
F3052_RS22095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3052_RS22100	COG3078	GTPase activator activity
F3052_RS22110	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3052_RS22110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3052_RS22115	COG0204	Acyl-transferase
F3052_RS22135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3052_RS22140	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3052_RS22145	COG3084	Protein conserved in bacteria
F3052_RS22150	COG0746	molybdenum cofactor guanylyltransferase activity
F3052_RS22155	COG1763	Mo-molybdopterin cofactor biosynthetic process
F3052_RS22185	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
F3052_RS22190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F3052_RS22195	COG1739	Uncharacterized protein family UPF0029
F3052_RS22210	COG0183	Belongs to the thiolase family
F3052_RS22215	COG0543	2 iron, 2 sulfur cluster binding
F3052_RS22220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F3052_RS22225	COG0250	Participates in transcription elongation, termination and antitermination
F3052_RS22230	COG0084	hydrolase, TatD family'
F3052_RS22235	COG0805	protein transport
F3052_RS22240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3052_RS22245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3052_RS22255	COG3165	ubiquinone biosynthetic process from chorismate
F3052_RS22265	COG1322	Protein conserved in bacteria
F3052_RS22270	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
F3052_RS22275	COG0412	Dienelactone hydrolase
F3052_RS22285	COG0583	DNA-binding transcription factor activity
F3052_RS22290	COG0697	spore germination
F3052_RS22295	COG0561	phosphatase activity
F3052_RS22300	COG2267	carboxylic ester hydrolase activity
F3052_RS22305	COG1280	lysine exporter protein (LysE YggA)
F3052_RS22310	COG1280	lysine exporter protein (LysE YggA)
F3052_RS22315	COG0514	ATP-dependent DNA helicase (RecQ)
F3052_RS22320	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
F3052_RS22325	COG2050	protein possibly involved in aromatic compounds catabolism
F3052_RS22330	COG2962	Rard protein
F3052_RS22345	COG0598	Magnesium transport protein CorA
F3052_RS22350	COG3698	Phosphodiester glycosidase
F3052_RS22355	COG0210	DNA helicase
F3052_RS22360	COG1011	Hydrolase
F3052_RS22370	COG3159	Protein conserved in bacteria
F3052_RS22380	COG5567	small periplasmic lipoprotein
F3052_RS22390	COG3072	Adenylate cyclase
F3052_RS22400	COG1587	Uroporphyrinogen-III synthase
F3052_RS22405	COG2959	enzyme of heme biosynthesis
F3052_RS22410	COG3071	HemY protein
F3052_RS22415	COG3119	arylsulfatase activity
F3052_RS22420	COG0641	radical SAM
F3052_RS22445	COG1113	amino acid transport
F3052_RS22465	COG2244	polysaccharide biosynthetic process
F3052_RS22470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F3052_RS22475	COG0456	acetyltransferase
F3052_RS22480	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F3052_RS22485	COG1088	dTDP-glucose 4,6-dehydratase activity
F3052_RS22490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F3052_RS22495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F3052_RS22500	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
F3052_RS22505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F3052_RS22510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F3052_RS22520	COG3118	belongs to the thioredoxin family
F3052_RS22535	COG0210	DNA helicase
F3052_RS22540	COG3692	DNA binding
F3052_RS22545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3052_RS22555	COG0583	DNA-binding transcription factor activity
F3052_RS22560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3052_RS22570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3052_RS22575	COG3978	acetolactate synthase activity
F3052_RS22595	COG0606	chelatase, subunit chli
F3052_RS22600	COG3085	chromosome segregation
F3052_RS22640	COG2186	Transcriptional regulator
F3052_RS22645	COG0477	Major facilitator Superfamily
F3052_RS22650	COG1609	Transcriptional regulator
F3052_RS22655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3052_RS22660	COG1879	ABC-type sugar transport system periplasmic component
F3052_RS22665	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3052_RS22670	COG1129	ABC transporter
F3052_RS22700	COG1522	sequence-specific DNA binding
F3052_RS22705	COG0716	FMN binding
F3052_RS22720	COG3312	ion transport
F3052_RS22770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3052_RS22775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F3052_RS22780	COG0573	inorganic phosphate transmembrane transporter activity
F3052_RS22785	COG0581	inorganic phosphate transmembrane transporter activity
F3052_RS22790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3052_RS22795	COG0704	Plays a role in the regulation of phosphate uptake
F3052_RS22800	COG3711	transcriptional antiterminator
F3052_RS22805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3052_RS22805	COG1263	PTS System
F3052_RS22805	COG2190	(PTS) system
F3052_RS22810	COG2723	6-phospho-beta-galactosidase activity
F3052_RS22820	COG2382	esterase
F3052_RS22825	COG0363	glucosamine-6-phosphate deaminase activity
F3052_RS22830	COG3196	Protein conserved in bacteria
F3052_RS22840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3052_RS22845	COG2252	PERMEase
F3052_RS22850	COG0431	NADPH-dependent FMN reductase
F3052_RS22855	COG2091	lysine biosynthetic process via aminoadipic acid
F3052_RS22870	COG0814	amino acid
F3052_RS22990	COG1349	DNA-binding transcription factor activity
F3052_RS22995	COG2084	Dehydrogenase
F3052_RS23010	COG5001	Diguanylate cyclase
F3052_RS23045	COG0840	transmembrane signaling receptor activity
F3052_RS23050	COG4372	Transposase
F3052_RS23055	COG3436	PFAM IS66 Orf2 family protein
F3052_RS23110	COG1192	Involved in chromosome partitioning
F3052_RS23190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3052_RS23300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3052_RS23430	COG4974	Belongs to the 'phage' integrase family
F3052_RS23570	COG0616	signal peptide processing
F3052_RS23690	COG5001	Diguanylate cyclase
F3052_RS23690	COG3300	MHYT domain
F3052_RS23760	COG1660	Displays ATPase and GTPase activities
F3052_RS23775	COG3173	Aminoglycoside phosphotransferase
F3052_RS23840	COG2186	Transcriptional regulator
F3052_RS23850	COG0246	Mannitol dehydrogenase
F3052_RS23870	COG3250	beta-galactosidase activity
F3052_RS23875	COG1309	transcriptional regulator
F3052_RS23880	COG3039	Transposase
F3052_RS23900	COG1309	transcriptional regulator
F3052_RS23915	COG1136	(ABC) transporter
F3052_RS23950	COG0589	response to stress
F3052_RS23955	COG0659	secondary active sulfate transmembrane transporter activity
F3052_RS24000	COG2826	transposase and inactivated derivatives, IS30 family
F3052_RS24010	COG3436	PFAM IS66 Orf2 family protein
F3052_RS24015	COG2433	Pfam Transposase IS66
F3052_RS24045	COG1121	(ABC) transporter
F3052_RS24080	COG2135	peptidase activity
F3052_RS24135	COG0629	single-stranded DNA binding