locus-tag	class	description
ECO111_RS00015	COG0527	aspartate kinase activity
ECO111_RS00015	COG0460	homoserine dehydrogenase
ECO111_RS00025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ECO111_RS00045	COG1115	amino acid carrier protein
ECO111_RS00050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECO111_RS00055	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECO111_RS00060	COG1584	GPR1 FUN34 yaaH family protein
ECO111_RS00065	COG4735	regulation of single-species biofilm formation
ECO111_RS00095	COG0583	DNA-binding transcription factor activity
ECO111_RS00105	COG3188	usher protein
ECO111_RS00125	COG0196	riboflavin kinase activity
ECO111_RS00140	COG1047	Peptidyl-prolyl cis-trans
ECO111_RS00170	COG0505	Belongs to the CarA family
ECO111_RS00175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ECO111_RS00230	COG0644	oxidoreductase
ECO111_RS00235	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECO111_RS00240	COG2271	Major facilitator Superfamily
ECO111_RS00255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ECO111_RS00295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECO111_RS00300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECO111_RS00305	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ECO111_RS00310	COG0564	pseudouridine synthase activity
ECO111_RS00320	COG0417	DNA replication proofreading
ECO111_RS00325	COG0235	Class ii aldolase
ECO111_RS00340	COG4977	sequence-specific DNA binding
ECO111_RS00345	COG0586	Pfam SNARE associated Golgi protein
ECO111_RS00355	COG1178	ABC-type Fe3 transport system permease component
ECO111_RS00360	COG4143	(ABC) transporter
ECO111_RS00375	COG2814	Major facilitator Superfamily
ECO111_RS00390	COG0473	3-isopropylmalate dehydrogenase activity
ECO111_RS00405	COG0583	DNA-binding transcription factor activity
ECO111_RS00410	COG0028	Belongs to the TPP enzyme family
ECO111_RS00415	COG0440	acetolactate synthase activity
ECO111_RS00425	COG1609	Transcriptional regulator
ECO111_RS00440	COG3116	cell division
ECO111_RS00445	COG0768	penicillin binding
ECO111_RS00450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECO111_RS00455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ECO111_RS00470	COG0772	Belongs to the SEDS family
ECO111_RS00485	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECO111_RS00490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ECO111_RS00495	COG0849	cell division
ECO111_RS00500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ECO111_RS00520	COG0494	nUDIX hydrolase
ECO111_RS00540	COG0237	dephospho-CoA kinase activity
ECO111_RS00550	COG1459	type II secretion system
ECO111_RS00555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECO111_RS00560	COG4969	Belongs to the N-Me-Phe pilin family
ECO111_RS00570	COG0157	Belongs to the NadC ModD family
ECO111_RS00575	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECO111_RS00580	COG3725	Membrane protein required for beta-lactamase induction
ECO111_RS00585	COG1113	amino acid transport
ECO111_RS00590	COG2186	Transcriptional regulator
ECO111_RS00595	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ECO111_RS00600	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECO111_RS00605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECO111_RS00610	COG3064	Membrane
ECO111_RS00615	COG1049	propionate catabolic process, 2-methylcitrate cycle
ECO111_RS00640	COG2132	Multicopper oxidase
ECO111_RS00645	COG4993	Dehydrogenase
ECO111_RS00650	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ECO111_RS00655	COG0288	reversible hydration of carbon dioxide
ECO111_RS00660	COG1131	(ABC) transporter
ECO111_RS00665	COG0842	Transport permease protein
ECO111_RS00670	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS00675	COG0726	polysaccharide deacetylase
ECO111_RS00685	COG5464	transposase or invertase
ECO111_RS00705	COG3539	Fimbrial protein
ECO111_RS00710	COG3539	Fimbrial protein
ECO111_RS00715	COG3539	Fimbrial protein
ECO111_RS00720	COG3188	usher protein
ECO111_RS00725	COG3121	Chaperone
ECO111_RS00730	COG3539	Fimbrial protein
ECO111_RS00735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ECO111_RS00740	COG0617	tRNA 3'-terminal CCA addition
ECO111_RS00750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECO111_RS00760	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ECO111_RS00765	COG1643	Atp-dependent helicase
ECO111_RS00775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ECO111_RS00780	COG4774	siderophore transport
ECO111_RS00785	COG1120	ATPase activity
ECO111_RS00790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECO111_RS00795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECO111_RS00815	COG2860	membrane
ECO111_RS00820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECO111_RS00835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECO111_RS00840	COG3835	regulator
ECO111_RS00850	COG1408	metallophosphoesterase
ECO111_RS00865	COG0024	Methionine aminopeptidase
ECO111_RS00890	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ECO111_RS00895	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ECO111_RS00900	COG0575	Belongs to the CDS family
ECO111_RS00905	COG0750	zinc metalloprotease
ECO111_RS00915	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ECO111_RS00920	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ECO111_RS00945	COG0587	DNA-directed DNA polymerase activity
ECO111_RS00955	COG1982	Orn Lys Arg decarboxylase major
ECO111_RS00960	COG0346	lactoylglutathione lyase activity
ECO111_RS00970	COG4568	rho-dependent transcription termination
ECO111_RS00980	COG4681	YaeQ
ECO111_RS00985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECO111_RS00990	COG3015	lipoprotein NlpE involved in copper resistance
ECO111_RS00995	COG0791	NLP P60 protein
ECO111_RS01000	COG0791	NLP P60 protein
ECO111_RS01010	COG1720	tRNA m6t6A37 methyltransferase activity
ECO111_RS01020	COG1464	Belongs to the NlpA lipoprotein family
ECO111_RS01025	COG2011	ABC-type metal ion transport system permease component
ECO111_RS01030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ECO111_RS01035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECO111_RS01070	COG0656	L-ascorbic acid biosynthetic process
ECO111_RS01075	COG0583	DNA-binding transcription factor activity
ECO111_RS01085	COG2226	methyltransferase
ECO111_RS01090	COG1388	LysM domain
ECO111_RS01090	COG0741	lytic transglycosylase activity
ECO111_RS01100	COG2226	methyltransferase
ECO111_RS01110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS01130	COG4104	PAAR repeat-containing protein
ECO111_RS01135	COG3157	Type VI secretion system effector, Hcp
ECO111_RS01235	COG3209	COG3209 Rhs family protein
ECO111_RS01245	COG5433	transposase activity
ECO111_RS01255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECO111_RS01265	COG1960	acyl-CoA dehydrogenase activity
ECO111_RS01275	COG0121	glutamine amidotransferase
ECO111_RS01280	COG3034	peptidoglycan biosynthetic process
ECO111_RS01285	COG3041	Addiction module toxin RelE StbE family
ECO111_RS01290	COG3077	Addiction module antitoxin, RelB DinJ family
ECO111_RS01295	COG0791	NLP P60 protein
ECO111_RS01325	COG1987	bacterial-type flagellum assembly
ECO111_RS01350	COG1677	Flagellar hook-basal body complex protein FliE
ECO111_RS01360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECO111_RS01380	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ECO111_RS01410	COG1815	bacterial-type flagellum-dependent cell motility
ECO111_RS01415	COG1558	bacterial-type flagellum-dependent cell motility
ECO111_RS01425	COG1749	Flagellar hook protein flgE
ECO111_RS01430	COG4787	bacterial-type flagellum-dependent cell motility
ECO111_RS01435	COG4786	Flagellar basal body rod
ECO111_RS01460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECO111_RS01475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECO111_RS01480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ECO111_RS01505	COG1191	sigma factor activity
ECO111_RS01510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ECO111_RS01525	COG0454	-acetyltransferase
ECO111_RS01530	COG1690	Belongs to the RtcB family
ECO111_RS01535	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECO111_RS01540	COG2195	Cleaves the N-terminal amino acid of tripeptides
ECO111_RS01560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECO111_RS01580	COG0582	viral genome integration into host DNA
ECO111_RS01605	COG2003	Belongs to the UPF0758 family
ECO111_RS01720	COG3708	Transcriptional regulator
ECO111_RS01720	COG2207	Transcriptional regulator
ECO111_RS01725	COG0656	L-ascorbic acid biosynthetic process
ECO111_RS01730	COG3059	membrane
ECO111_RS01740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECO111_RS01745	COG2207	Transcriptional regulator
ECO111_RS01750	COG0247	lactate metabolic process
ECO111_RS01755	COG1139	Iron-sulfur cluster binding protein
ECO111_RS01760	COG1556	Lactate utilization protein
ECO111_RS01790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECO111_RS01800	COG2771	luxR family
ECO111_RS01800	COG2200	EAL domain
ECO111_RS01805	COG0583	DNA-binding transcription factor activity
ECO111_RS01815	COG0666	response to abiotic stimulus
ECO111_RS01825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECO111_RS01830	COG1304	FMN binding
ECO111_RS01835	COG0549	Belongs to the carbamate kinase family
ECO111_RS01840	COG0402	S-adenosylhomocysteine deaminase activity
ECO111_RS01850	COG1879	ABC-type sugar transport system periplasmic component
ECO111_RS01855	COG1129	ABC transporter
ECO111_RS01860	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECO111_RS01870	COG1064	alcohol dehydrogenase
ECO111_RS01885	COG1280	lysine exporter protein (LysE YggA)
ECO111_RS01895	COG3829	transcription factor binding
ECO111_RS01900	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ECO111_RS01905	COG0372	Belongs to the citrate synthase family
ECO111_RS01910	COG2079	MmgE PrpD family protein
ECO111_RS01915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ECO111_RS01920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ECO111_RS01925	COG0402	S-adenosylhomocysteine deaminase activity
ECO111_RS01930	COG0583	DNA-binding transcription factor activity
ECO111_RS01935	COG0288	reversible hydration of carbon dioxide
ECO111_RS01945	COG2807	transmembrane transport
ECO111_RS01950	COG2223	nitrite transmembrane transporter activity
ECO111_RS01955	COG3250	beta-galactosidase activity
ECO111_RS01960	COG1609	Transcriptional regulator
ECO111_RS01965	COG1414	Transcriptional regulator
ECO111_RS02000	COG2814	Major facilitator Superfamily
ECO111_RS02005	COG3122	Protein conserved in bacteria
ECO111_RS02035	COG1215	transferase activity, transferring glycosyl groups
ECO111_RS02040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ECO111_RS02045	COG4521	taurine ABC transporter
ECO111_RS02050	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ECO111_RS02060	COG2175	clavaminate synthase activity
ECO111_RS02065	COG0113	porphobilinogen synthase activity
ECO111_RS02075	COG3468	outer membrane autotransporter barrel domain protein
ECO111_RS02080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECO111_RS02085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECO111_RS02095	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ECO111_RS02115	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECO111_RS02130	COG1785	Belongs to the alkaline phosphatase family
ECO111_RS02140	COG3706	GGDEF domain
ECO111_RS02145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ECO111_RS02170	COG4126	flavin adenine dinucleotide binding
ECO111_RS02190	COG1940	carbohydrate kinase activity
ECO111_RS02195	COG2814	Major facilitator Superfamily
ECO111_RS02200	COG0419	ATPase involved in DNA repair
ECO111_RS02205	COG0420	3'-5' exonuclease activity
ECO111_RS02210	COG0745	RESPONSE REGULATOR receiver
ECO111_RS02215	COG5002	protein histidine kinase activity
ECO111_RS02220	COG1114	Component of the transport system for branched-chain amino acids
ECO111_RS02225	COG1113	amino acid transport
ECO111_RS02250	COG1862	Preprotein translocase
ECO111_RS02255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECO111_RS02260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECO111_RS02265	COG1403	HNH endonuclease
ECO111_RS02275	COG3248	Nucleoside-binding outer membrane protein
ECO111_RS02280	COG4238	major outer membrane lipoprotein
ECO111_RS02290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECO111_RS02290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECO111_RS02305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ECO111_RS02310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ECO111_RS02315	COG0667	Aldo Keto reductase
ECO111_RS02325	COG0142	geranyltranstransferase activity
ECO111_RS02340	COG0693	protein deglycase activity
ECO111_RS02345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ECO111_RS02355	COG2814	Major facilitator Superfamily
ECO111_RS02380	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ECO111_RS02385	COG1845	cytochrome c oxidase, subunit III
ECO111_RS02390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ECO111_RS02395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ECO111_RS02400	COG2223	nitrite transmembrane transporter activity
ECO111_RS02405	COG3056	Lipoprotein
ECO111_RS02410	COG0271	Belongs to the BolA IbaG family
ECO111_RS02435	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ECO111_RS02440	COG0776	regulation of translation
ECO111_RS02445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECO111_RS02450	COG1555	photosystem II stabilization
ECO111_RS02455	COG0824	Thioesterase
ECO111_RS02465	COG4533	DNA binding
ECO111_RS02475	COG1522	sequence-specific DNA binding
ECO111_RS02480	COG1132	(ABC) transporter
ECO111_RS02485	COG1132	(ABC) transporter
ECO111_RS02490	COG0347	Belongs to the P(II) protein family
ECO111_RS02495	COG0004	ammonium transporteR
ECO111_RS02500	COG1946	Acyl-CoA thioesterase
ECO111_RS02505	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ECO111_RS02510	COG3695	enzyme binding
ECO111_RS02515	COG5507	3-demethylubiquinone-9 3-methyltransferase
ECO111_RS02520	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECO111_RS02530	COG0110	maltose O-acetyltransferase activity
ECO111_RS02545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECO111_RS02550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECO111_RS02555	COG1309	transcriptional regulator
ECO111_RS02560	COG1196	nuclear chromosome segregation
ECO111_RS02560	COG3264	Mechanosensitive ion channel
ECO111_RS02590	COG3547	Transposase (IS116 IS110 IS902 family)
ECO111_RS02600	COG3923	Primosomal replication protein n
ECO111_RS02605	COG2832	Protein of unknown function (DUF454)
ECO111_RS02615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ECO111_RS02650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECO111_RS02655	COG4651	solute:proton antiporter activity
ECO111_RS02655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECO111_RS02660	COG2223	nitrite transmembrane transporter activity
ECO111_RS02665	COG0737	Belongs to the 5'-nucleotidase family
ECO111_RS02670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECO111_RS02675	COG3735	TraB family
ECO111_RS02680	COG3093	addiction module antidote protein HigA
ECO111_RS02685	COG2217	Heavy metal translocating P-type atpase
ECO111_RS02695	COG0531	amino acid
ECO111_RS02700	COG0789	Transcriptional regulator
ECO111_RS02705	COG1585	Membrane protein implicated in regulation of membrane protease activity
ECO111_RS02710	COG0330	HflC and HflK could
ECO111_RS02715	COG4619	ABC transporter
ECO111_RS02720	COG0390	transport system, permease component
ECO111_RS02725	COG3118	belongs to the thioredoxin family
ECO111_RS02730	COG0300	oxidoreductase activity
ECO111_RS02735	COG2755	lipolytic protein G-D-S-L family
ECO111_RS02740	COG4181	ATPase activity
ECO111_RS02745	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ECO111_RS02750	COG3209	COG3209 Rhs family protein
ECO111_RS02755	COG3209	COG3209 Rhs family protein
ECO111_RS02765	COG2801	Transposase and inactivated derivatives
ECO111_RS02775	COG0583	DNA-binding transcription factor activity
ECO111_RS02785	COG1414	Transcriptional regulator
ECO111_RS02790	COG3960	tartronate-semialdehyde synthase activity
ECO111_RS02795	COG3622	Belongs to the hyi family
ECO111_RS02800	COG2084	Dehydrogenase
ECO111_RS02805	COG1953	Uracil, thiamine, allantoin
ECO111_RS02815	COG2233	PERMEase
ECO111_RS02820	COG1929	Belongs to the glycerate kinase type-1 family
ECO111_RS02825	COG3257	ureidoglycine aminohydrolase activity
ECO111_RS02830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECO111_RS02835	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECO111_RS02840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECO111_RS02845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECO111_RS02855	COG0549	Belongs to the carbamate kinase family
ECO111_RS02860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ECO111_RS02865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ECO111_RS02875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECO111_RS02885	COG1988	membrane-bound metal-dependent
ECO111_RS02890	COG2501	S4 domain
ECO111_RS02900	COG3539	Fimbrial protein
ECO111_RS02905	COG3121	Chaperone
ECO111_RS02910	COG3188	usher protein
ECO111_RS02915	COG3539	Fimbrial protein
ECO111_RS02920	COG3539	Fimbrial protein
ECO111_RS02925	COG2197	response regulator
ECO111_RS02935	COG0582	viral genome integration into host DNA
ECO111_RS03000	COG1196	nuclear chromosome segregation
ECO111_RS03015	COG0500	methyltransferase
ECO111_RS03030	COG4571	Outer membrane protease
ECO111_RS03040	COG2207	Transcriptional regulator
ECO111_RS03050	COG4783	chaperone-mediated protein folding
ECO111_RS03055	COG1215	transferase activity, transferring glycosyl groups
ECO111_RS03060	COG5433	transposase activity
ECO111_RS03065	COG4104	PAAR repeat-containing protein
ECO111_RS03065	COG3209	COG3209 Rhs family protein
ECO111_RS03080	COG3209	COG3209 Rhs family protein
ECO111_RS03080	COG4104	PAAR repeat-containing protein
ECO111_RS03090	COG3501	Rhs element vgr protein
ECO111_RS03095	COG5002	protein histidine kinase activity
ECO111_RS03100	COG0745	RESPONSE REGULATOR receiver
ECO111_RS03105	COG1538	Outer membrane efflux protein
ECO111_RS03110	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECO111_RS03115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECO111_RS03120	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECO111_RS03125	COG1113	amino acid transport
ECO111_RS03130	COG0668	transmembrane transport
ECO111_RS03135	COG0778	Nitroreductase
ECO111_RS03140	COG2315	Protein conserved in bacteria
ECO111_RS03175	COG2977	Belongs to the P-Pant transferase superfamily
ECO111_RS03180	COG4771	TonB-dependent receptor
ECO111_RS03185	COG2382	esterase
ECO111_RS03190	COG3251	PFAM MbtH domain protein
ECO111_RS03195	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ECO111_RS03195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ECO111_RS03200	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECO111_RS03205	COG1120	ATPase activity
ECO111_RS03210	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECO111_RS03215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECO111_RS03225	COG4592	Periplasmic binding protein
ECO111_RS03230	COG1169	isochorismate synthase
ECO111_RS03235	COG1021	2,3-dihydroxybenzoate-AMP ligase
ECO111_RS03240	COG1535	isochorismatase
ECO111_RS03240	COG3433	isochorismatase activity
ECO111_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS03250	COG2050	protein possibly involved in aromatic compounds catabolism
ECO111_RS03255	COG1966	Carbon starvation protein
ECO111_RS03260	COG2879	small protein
ECO111_RS03265	COG0371	Dehydrogenase
ECO111_RS03270	COG0436	Aminotransferase
ECO111_RS03285	COG0583	DNA-binding transcription factor activity
ECO111_RS03290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECO111_RS03295	COG0450	alkyl hydroperoxide reductase
ECO111_RS03300	COG3634	alkyl hydroperoxide reductase activity
ECO111_RS03305	COG0589	response to stress
ECO111_RS03310	COG1063	alcohol dehydrogenase
ECO111_RS03320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECO111_RS03325	COG3719	Belongs to the RNase T2 family
ECO111_RS03330	COG0471	metal ion transport
ECO111_RS03345	COG3051	citrate lyase alpha subunit
ECO111_RS03350	COG2301	Belongs to the HpcH HpaI aldolase family
ECO111_RS03360	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ECO111_RS03365	COG3290	protein histidine kinase activity
ECO111_RS03370	COG4565	transcriptional regulatory protein
ECO111_RS03375	COG3069	C4-dicarboxylate transmembrane transporter activity
ECO111_RS03395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECO111_RS03400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECO111_RS03410	COG0583	DNA-binding transcription factor activity
ECO111_RS03430	COG1686	Belongs to the peptidase S11 family
ECO111_RS03435	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECO111_RS03440	COG0772	Belongs to the SEDS family
ECO111_RS03445	COG0768	penicillin binding
ECO111_RS03455	COG0799	negative regulation of ribosome biogenesis
ECO111_RS03460	COG0406	alpha-ribazole phosphatase activity
ECO111_RS03470	COG1466	dna polymerase III delta subunit
ECO111_RS03485	COG2888	peptidyl-tyrosine sulfation
ECO111_RS03490	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECO111_RS03500	COG2214	Heat shock protein DnaJ domain protein
ECO111_RS03505	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECO111_RS03515	COG2214	Heat shock protein DnaJ domain protein
ECO111_RS03520	COG0443	Heat shock 70 kDa protein
ECO111_RS03530	COG1126	abc transporter atp-binding protein
ECO111_RS03535	COG0765	amino acid transport
ECO111_RS03540	COG0765	amino acid transport
ECO111_RS03545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECO111_RS03555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ECO111_RS03560	COG4535	Mg2 and Co2 transporter CorC
ECO111_RS03570	COG1702	phosphate starvation-inducible protein PhoH
ECO111_RS03580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECO111_RS03620	COG0367	asparagine synthase
ECO111_RS03625	COG0647	UMP catabolic process
ECO111_RS03630	COG1940	carbohydrate kinase activity
ECO111_RS03630	COG1846	Transcriptional regulator
ECO111_RS03635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECO111_RS03645	COG2190	(PTS) system
ECO111_RS03645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS03645	COG1263	PTS System
ECO111_RS03665	COG0735	belongs to the Fur family
ECO111_RS03680	COG0716	FMN binding
ECO111_RS03690	COG0596	Alpha beta hydrolase
ECO111_RS03695	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ECO111_RS03700	COG0033	Phosphoglucomutase
ECO111_RS03710	COG1982	Orn Lys Arg decarboxylase major
ECO111_RS03720	COG0745	RESPONSE REGULATOR receiver
ECO111_RS03725	COG2205	protein histidine kinase activity
ECO111_RS03755	COG3209	COG3209 Rhs family protein
ECO111_RS03765	COG3209	COG3209 Rhs family protein
ECO111_RS03780	COG3272	Protein of unknown function (DUF1722)
ECO111_RS03785	COG0415	Belongs to the DNA photolyase family
ECO111_RS03795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ECO111_RS03800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ECO111_RS03805	COG1984	allophanate hydrolase subunit 2
ECO111_RS03820	COG3180	Ammonia monooxygenase
ECO111_RS03825	COG3539	Fimbrial protein
ECO111_RS03830	COG3121	Chaperone
ECO111_RS03835	COG3188	usher protein
ECO111_RS03840	COG3539	Fimbrial protein
ECO111_RS03845	COG0372	Belongs to the citrate synthase family
ECO111_RS03855	COG2009	succinate dehydrogenase
ECO111_RS03860	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ECO111_RS03865	COG1053	succinate dehydrogenase
ECO111_RS03870	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECO111_RS03880	COG0567	Dehydrogenase, E1 component
ECO111_RS03885	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECO111_RS03895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECO111_RS03900	COG2188	Transcriptional regulator
ECO111_RS03905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS03905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS03905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS03910	COG0383	alpha-mannosidase activity
ECO111_RS03920	COG1271	oxidase subunit
ECO111_RS03925	COG1294	oxidase, subunit
ECO111_RS03930	COG4890	Cyd operon protein YbgT
ECO111_RS03935	COG3790	cyd operon protein YbgE
ECO111_RS03940	COG0824	Thioesterase
ECO111_RS03945	COG0811	peptide transport
ECO111_RS03950	COG0848	biopolymer transport protein
ECO111_RS03955	COG3064	Membrane
ECO111_RS03965	COG2885	chlorophyll binding
ECO111_RS03970	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ECO111_RS04015	COG3201	nicotinamide mononucleotide transporter
ECO111_RS04020	COG1230	cation diffusion facilitator family transporter
ECO111_RS04035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECO111_RS04045	COG2017	converts alpha-aldose to the beta-anomer
ECO111_RS04055	COG1085	galactose-1-phosphate uridylyltransferase
ECO111_RS04060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ECO111_RS04065	COG1119	ATPase activity
ECO111_RS04070	COG3585	molybdate ion transport
ECO111_RS04070	COG2005	Transcriptional regulator
ECO111_RS04080	COG0725	ABC transporter, periplasmic molybdate-binding protein
ECO111_RS04085	COG4149	molybdate abc transporter
ECO111_RS04095	COG0561	phosphatase activity
ECO111_RS04105	COG0583	DNA-binding transcription factor activity
ECO111_RS04115	COG0471	metal ion transport
ECO111_RS04120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECO111_RS04125	COG4677	pectinesterase activity
ECO111_RS04130	COG0582	viral genome integration into host DNA
ECO111_RS04135	COG3772	lysozyme
ECO111_RS04150	COG3772	lysozyme
ECO111_RS04350	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECO111_RS04390	COG1881	PFAM PEBP family protein
ECO111_RS04395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ECO111_RS04410	COG2226	methyltransferase
ECO111_RS04415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECO111_RS04425	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ECO111_RS04440	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECO111_RS04450	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ECO111_RS04455	COG0314	molybdopterin synthase activity
ECO111_RS04460	COG0670	Belongs to the BI1 family
ECO111_RS04465	COG0670	Belongs to the BI1 family
ECO111_RS04470	COG0392	lysyltransferase activity
ECO111_RS04475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECO111_RS04480	COG3568	Endonuclease Exonuclease Phosphatase
ECO111_RS04490	COG0842	Transport permease protein
ECO111_RS04495	COG0842	Transport permease protein
ECO111_RS04500	COG1131	(ABC) transporter
ECO111_RS04510	COG1309	transcriptional regulator
ECO111_RS04515	COG0513	Belongs to the DEAD box helicase family
ECO111_RS04520	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ECO111_RS04525	COG1199	ATP-dependent helicase activity
ECO111_RS04530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECO111_RS04535	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECO111_RS04545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECO111_RS04555	COG4774	siderophore transport
ECO111_RS04570	COG0668	transmembrane transport
ECO111_RS04580	COG1126	abc transporter atp-binding protein
ECO111_RS04585	COG0765	amino acid transport
ECO111_RS04590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECO111_RS04605	COG5006	permease, DMT superfamily
ECO111_RS04610	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ECO111_RS04615	COG2194	sulfuric ester hydrolase activity
ECO111_RS04625	COG1321	iron dependent repressor
ECO111_RS04630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECO111_RS04635	COG1376	ErfK ybiS ycfS ynhG family protein
ECO111_RS04675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ECO111_RS04680	COG0488	(ABC) transporter
ECO111_RS04690	COG0561	phosphatase activity
ECO111_RS04695	COG1882	Formate acetyltransferase
ECO111_RS04700	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECO111_RS04705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECO111_RS04710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECO111_RS04715	COG0303	'Molybdopterin
ECO111_RS04720	COG1446	asparaginase
ECO111_RS04745	COG2200	EAL domain
ECO111_RS04750	COG2199	diguanylate cyclase activity
ECO111_RS04765	COG2133	pyrroloquinoline quinone binding
ECO111_RS04770	COG0625	glutathione transferase activity
ECO111_RS04775	COG1686	Belongs to the peptidase S11 family
ECO111_RS04780	COG1349	DNA-binding transcription factor activity
ECO111_RS04785	COG0671	phosphoesterase, PA-phosphatase related
ECO111_RS04790	COG2814	Major facilitator Superfamily
ECO111_RS04800	COG0561	phosphatase activity
ECO111_RS04810	COG3226	Transcriptional regulator
ECO111_RS04825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECO111_RS04835	COG0778	Nitroreductase
ECO111_RS04855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECO111_RS04860	COG3842	ATPase activity
ECO111_RS04865	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECO111_RS04870	COG1177	transmembrane transport
ECO111_RS04885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECO111_RS04890	COG4160	amino acid transport
ECO111_RS04895	COG4215	(ABC) transporter
ECO111_RS04900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECO111_RS04905	COG1126	abc transporter atp-binding protein
ECO111_RS04920	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECO111_RS04925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECO111_RS04930	COG0702	epimerase
ECO111_RS04935	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ECO111_RS04940	COG0028	Belongs to the TPP enzyme family
ECO111_RS04945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECO111_RS04955	COG2431	L-lysine efflux transmembrane transporter activity
ECO111_RS04970	COG3593	DNA synthesis involved in DNA repair
ECO111_RS04975	COG2990	Protein conserved in bacteria
ECO111_RS04980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECO111_RS04985	COG1136	(ABC) transporter
ECO111_RS04985	COG0577	efflux transmembrane transporter activity
ECO111_RS04990	COG1278	Cold shock
ECO111_RS05000	COG0542	response to heat
ECO111_RS05020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ECO111_RS05025	COG4988	ABC transporter
ECO111_RS05030	COG0492	ferredoxin-NADP+ reductase activity
ECO111_RS05035	COG1522	sequence-specific DNA binding
ECO111_RS05050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ECO111_RS05060	COG0243	molybdopterin cofactor binding
ECO111_RS05065	COG0437	4 iron, 4 sulfur cluster binding
ECO111_RS05070	COG3302	dmso reductase anchor subunit
ECO111_RS05075	COG1335	isochorismatase
ECO111_RS05085	COG0531	amino acid
ECO111_RS05090	COG0583	DNA-binding transcription factor activity
ECO111_RS05095	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECO111_RS05100	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECO111_RS05105	COG1882	Formate acetyltransferase
ECO111_RS05110	COG2116	formate transmembrane transporter activity
ECO111_RS05115	COG1944	ATP diphosphatase activity
ECO111_RS05120	COG2323	membrane
ECO111_RS05135	COG0501	Belongs to the peptidase M48B family
ECO111_RS05145	COG0539	negative regulation of cytoplasmic translation
ECO111_RS05155	COG0658	competence protein
ECO111_RS05155	COG2333	competence protein COMEC
ECO111_RS05160	COG1132	(ABC) transporter
ECO111_RS05170	COG3214	Protein conserved in bacteria
ECO111_RS05185	COG3173	Aminoglycoside phosphotransferase
ECO111_RS05190	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECO111_RS05195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECO111_RS05205	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ECO111_RS05215	COG2989	Protein conserved in bacteria
ECO111_RS05220	COG3108	Peptidase M15
ECO111_RS05225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECO111_RS05230	COG1448	Aminotransferase
ECO111_RS05255	COG0308	aminopeptidase N
ECO111_RS05265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECO111_RS05275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ECO111_RS05280	COG0431	NADPH-dependent FMN reductase
ECO111_RS05285	COG3539	Fimbrial protein
ECO111_RS05290	COG3121	Chaperone
ECO111_RS05295	COG3188	usher protein
ECO111_RS05300	COG3539	Fimbrial protein
ECO111_RS05305	COG3539	Fimbrial protein
ECO111_RS05310	COG3539	Fimbrial protein
ECO111_RS05315	COG3121	Chaperone
ECO111_RS05330	COG0633	Ferredoxin
ECO111_RS05330	COG3217	Mosc domain protein beta barrel domain protein
ECO111_RS05340	COG0488	(ABC) transporter
ECO111_RS05345	COG2995	paraquat-inducible protein a
ECO111_RS05350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECO111_RS05350	COG3008	intermembrane lipid transfer
ECO111_RS05355	COG3009	Protein conserved in bacteria
ECO111_RS05360	COG3130	regulation of translation
ECO111_RS05370	COG1067	ATP-dependent peptidase activity
ECO111_RS05380	COG2885	chlorophyll binding
ECO111_RS05380	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ECO111_RS05395	COG3070	regulator of competence-specific genes
ECO111_RS05400	COG1289	transmembrane transporter activity
ECO111_RS05405	COG3304	Inner membrane component domain
ECO111_RS05410	COG0210	DNA helicase
ECO111_RS05430	COG1832	CoA-binding protein
ECO111_RS05445	COG1254	Belongs to the acylphosphatase family
ECO111_RS05450	COG2920	part of a sulfur-relay system
ECO111_RS05455	COG0670	Belongs to the BI1 family
ECO111_RS05475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS05490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS05590	COG1403	HNH endonuclease
ECO111_RS05595	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECO111_RS05615	COG2207	Transcriptional regulator
ECO111_RS05665	COG3772	lysozyme
ECO111_RS05720	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ECO111_RS05725	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ECO111_RS05730	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ECO111_RS05735	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECO111_RS05740	COG1999	signal sequence binding
ECO111_RS05745	COG1773	rubredoxin
ECO111_RS05750	COG1271	oxidase subunit
ECO111_RS05755	COG1294	oxidase, subunit
ECO111_RS05770	COG0489	protein tyrosine kinase activity
ECO111_RS05770	COG3206	protein involved in exopolysaccharide biosynthesis
ECO111_RS05775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ECO111_RS05780	COG1596	polysaccharide export
ECO111_RS05785	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECO111_RS05805	COG1278	Cold shock
ECO111_RS05810	COG1278	Cold shock
ECO111_RS05825	COG0348	domain, Protein
ECO111_RS05830	COG2198	Histidine kinase
ECO111_RS05830	COG0784	Response regulator, receiver
ECO111_RS05830	COG2205	protein histidine kinase activity
ECO111_RS05835	COG1879	ABC-type sugar transport system periplasmic component
ECO111_RS05840	COG0745	RESPONSE REGULATOR receiver
ECO111_RS05845	COG3005	denitrification pathway
ECO111_RS05850	COG0243	molybdopterin cofactor binding
ECO111_RS05890	COG0582	viral genome integration into host DNA
ECO111_RS05980	COG0515	serine threonine protein kinase
ECO111_RS05980	COG2815	serine threonine protein kinase
ECO111_RS06120	COG3772	lysozyme
ECO111_RS06200	COG3547	Transposase (IS116 IS110 IS902 family)
ECO111_RS06285	COG3111	PFAM Bacterial OB fold (BOF) protein
ECO111_RS06320	COG3561	AntA/AntB antirepressor
ECO111_RS06330	COG3729	General stress protein
ECO111_RS06335	COG2233	PERMEase
ECO111_RS06370	COG1309	transcriptional regulator
ECO111_RS06375	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECO111_RS06375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECO111_RS06375	COG0506	proline dehydrogenase activity
ECO111_RS06385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECO111_RS06400	COG2822	iron ion transport
ECO111_RS06415	COG1702	phosphate starvation-inducible protein PhoH
ECO111_RS06425	COG0582	viral genome integration into host DNA
ECO111_RS06455	COG4983	Phage plasmid primase, P4 family domain protein
ECO111_RS06470	COG4372	Transposase
ECO111_RS06495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ECO111_RS06500	COG2194	sulfuric ester hydrolase activity
ECO111_RS06510	COG0829	nickel cation binding
ECO111_RS06560	COG0254	rRNA binding
ECO111_RS06585	COG2433	Pfam Transposase IS66
ECO111_RS06600	COG3436	PFAM IS66 Orf2 family protein
ECO111_RS06605	COG4372	Transposase
ECO111_RS06610	COG4372	Transposase
ECO111_RS06615	COG4372	Transposase
ECO111_RS06645	COG1358	cellular component organization or biogenesis
ECO111_RS06710	COG4771	TonB-dependent receptor
ECO111_RS06730	COG2801	Transposase and inactivated derivatives
ECO111_RS06805	COG2831	hemolysin activation secretion protein
ECO111_RS06815	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ECO111_RS06820	COG3969	phosphoadenosine phosphosulfate
ECO111_RS06825	COG3969	phosphoadenosine phosphosulfate
ECO111_RS06830	COG1475	DNA binding
ECO111_RS06920	COG2003	Belongs to the UPF0758 family
ECO111_RS06975	COG3381	protein complex oligomerization
ECO111_RS06985	COG1462	curli production assembly transport component CsgG
ECO111_RS07000	COG2197	response regulator
ECO111_RS07030	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECO111_RS07035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECO111_RS07060	COG2943	transferase activity, transferring hexosyl groups
ECO111_RS07065	COG5645	(Lipo)protein
ECO111_RS07085	COG1560	Kdo2-lipid A biosynthetic process
ECO111_RS07095	COG2353	YceI-like domain
ECO111_RS07100	COG3038	cytochrome b561
ECO111_RS07135	COG2999	glutathione oxidoreductase activity
ECO111_RS07145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECO111_RS07155	COG0673	inositol 2-dehydrogenase activity
ECO111_RS07160	COG0728	peptidoglycan biosynthetic process
ECO111_RS07165	COG3418	PFAM FlgN family protein
ECO111_RS07170	COG2747	anti-sigma28 factor FlgM
ECO111_RS07175	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ECO111_RS07180	COG1815	bacterial-type flagellum-dependent cell motility
ECO111_RS07185	COG1558	bacterial-type flagellum-dependent cell motility
ECO111_RS07190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ECO111_RS07195	COG1749	Flagellar hook protein flgE
ECO111_RS07200	COG4787	bacterial-type flagellum-dependent cell motility
ECO111_RS07205	COG4786	Flagellar basal body rod
ECO111_RS07220	COG3951	Flagellar rod assembly protein muramidase FlgJ
ECO111_RS07220	COG1705	Flagellar rod assembly protein muramidase FlgJ
ECO111_RS07225	COG1256	bacterial-type flagellum assembly
ECO111_RS07230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECO111_RS07235	COG1530	ribonuclease E activity
ECO111_RS07245	COG0564	pseudouridine synthase activity
ECO111_RS07250	COG0424	maF-like protein
ECO111_RS07255	COG1399	metal-binding, possibly nucleic acid-binding protein
ECO111_RS07275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ECO111_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS07290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECO111_RS07295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECO111_RS07300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ECO111_RS07310	COG0470	DNA polymerase III
ECO111_RS07315	COG0084	hydrolase, TatD family'
ECO111_RS07320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS07320	COG1263	PTS System
ECO111_RS07325	COG4773	Receptor
ECO111_RS07330	COG0537	adenosine 5'-monophosphoramidase activity
ECO111_RS07335	COG5633	Lipoprotein
ECO111_RS07340	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ECO111_RS07360	COG1252	NADH dehydrogenase
ECO111_RS07365	COG3134	Outer membrane lipoprotein
ECO111_RS07370	COG1309	transcriptional regulator
ECO111_RS07380	COG1376	ErfK ybiS ycfS ynhG family protein
ECO111_RS07380	COG1388	LysM domain
ECO111_RS07385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ECO111_RS07390	COG4763	Acyl-transferase
ECO111_RS07395	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECO111_RS07400	COG1136	(ABC) transporter
ECO111_RS07405	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECO111_RS07415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ECO111_RS07420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ECO111_RS07430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECO111_RS07435	COG1177	transmembrane transport
ECO111_RS07440	COG0582	viral genome integration into host DNA
ECO111_RS07450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS07500	COG1846	Transcriptional regulator
ECO111_RS07550	COG1403	HNH endonuclease
ECO111_RS07555	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECO111_RS07605	COG3772	lysozyme
ECO111_RS07775	COG3328	transposase activity
ECO111_RS07810	COG2850	peptidyl-arginine hydroxylation
ECO111_RS07815	COG2205	protein histidine kinase activity
ECO111_RS07825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ECO111_RS07845	COG1187	pseudouridine synthase activity
ECO111_RS07850	COG0538	isocitrate dehydrogenase activity
ECO111_RS07865	COG5562	phage envelope protein
ECO111_RS07870	COG0789	Transcriptional regulator
ECO111_RS07875	COG2200	EAL domain
ECO111_RS07900	COG2200	EAL domain
ECO111_RS07950	COG2894	cell division
ECO111_RS07980	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECO111_RS07995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECO111_RS08020	COG2719	SpoVR family
ECO111_RS08030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECO111_RS08040	COG1619	proteins homologs of microcin C7 resistance protein MccF
ECO111_RS08050	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ECO111_RS08070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS08070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECO111_RS08070	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ECO111_RS08075	COG1461	Dihydroxyacetone kinase
ECO111_RS08080	COG2376	Dihydroxyacetone kinase
ECO111_RS08085	COG3284	Transcriptional regulator
ECO111_RS08090	COG3468	outer membrane autotransporter barrel domain protein
ECO111_RS08100	COG0012	GTP binding
ECO111_RS08115	COG0659	secondary active sulfate transmembrane transporter activity
ECO111_RS08120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ECO111_RS08145	COG2890	protein-(glutamine-N5) methyltransferase activity
ECO111_RS08150	COG3094	Invasion gene expression up-regulator, SirB
ECO111_RS08155	COG2912	Transglutaminase-like superfamily
ECO111_RS08180	COG0387	Pfam Sodium calcium exchanger
ECO111_RS08185	COG4572	Cation transport regulator
ECO111_RS08190	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ECO111_RS08195	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ECO111_RS08200	COG4932	domain protein
ECO111_RS08205	COG2197	response regulator
ECO111_RS08210	COG3850	Histidine kinase
ECO111_RS08220	COG2223	nitrite transmembrane transporter activity
ECO111_RS08225	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ECO111_RS08230	COG1140	nitrate reductase beta subunit
ECO111_RS08235	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECO111_RS08240	COG2181	nitrate reductase activity
ECO111_RS08260	COG0788	formyltetrahydrofolate deformylase activity
ECO111_RS08270	COG1752	Esterase of the alpha-beta hydrolase superfamily
ECO111_RS08275	COG0745	RESPONSE REGULATOR receiver
ECO111_RS08280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ECO111_RS08290	COG1435	thymidine kinase activity
ECO111_RS08305	COG1454	alcohol dehydrogenase
ECO111_RS08305	COG1012	belongs to the aldehyde dehydrogenase family
ECO111_RS08310	COG2095	MarC family integral membrane protein
ECO111_RS08315	COG4166	transmembrane transport
ECO111_RS08320	COG0601	transmembrane transport
ECO111_RS08325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECO111_RS08330	COG0444	Belongs to the ABC transporter superfamily
ECO111_RS08335	COG4608	Belongs to the ABC transporter superfamily
ECO111_RS08355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECO111_RS08360	COG2350	Protein conserved in bacteria
ECO111_RS08385	COG1846	Transcriptional regulator
ECO111_RS08435	COG1403	HNH endonuclease
ECO111_RS08440	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECO111_RS08445	COG0484	heat shock protein binding
ECO111_RS08500	COG3772	lysozyme
ECO111_RS08530	COG0740	serine-type endopeptidase activity
ECO111_RS08605	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECO111_RS08635	COG3685	Protein conserved in bacteria
ECO111_RS08640	COG3685	Protein conserved in bacteria
ECO111_RS08645	COG3729	General stress protein
ECO111_RS08660	COG0135	phosphoribosylanthranilate isomerase activity
ECO111_RS08660	COG0134	indole-3-glycerol-phosphate synthase activity
ECO111_RS08665	COG0512	Glutamine amidotransferase of anthranilate synthase
ECO111_RS08665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECO111_RS08670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECO111_RS08675	COG0613	PHP domain protein
ECO111_RS08680	COG0009	L-threonylcarbamoyladenylate synthase
ECO111_RS08685	COG1187	pseudouridine synthase activity
ECO111_RS08690	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ECO111_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS08705	COG0616	signal peptide processing
ECO111_RS08720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECO111_RS08725	COG0583	DNA-binding transcription factor activity
ECO111_RS08745	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECO111_RS08755	COG0671	phosphoesterase, PA-phosphatase related
ECO111_RS08760	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ECO111_RS08765	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ECO111_RS08775	COG0023	Translation Initiation Factor
ECO111_RS08785	COG1349	DNA-binding transcription factor activity
ECO111_RS08810	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECO111_RS08810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECO111_RS08815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ECO111_RS08825	COG2852	Protein conserved in bacteria
ECO111_RS08830	COG4172	Belongs to the ABC transporter superfamily
ECO111_RS08835	COG4172	Belongs to the ABC transporter superfamily
ECO111_RS08840	COG4171	peptide transport system, permease
ECO111_RS08845	COG4168	peptide transport system, permease
ECO111_RS08850	COG4166	transmembrane transport
ECO111_RS08865	COG0531	amino acid
ECO111_RS08870	COG0174	glutamine synthetase
ECO111_RS08875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ECO111_RS08880	COG1396	sequence-specific DNA binding
ECO111_RS08880	COG1917	Cupin 2, conserved barrel domain protein
ECO111_RS08885	COG1012	belongs to the aldehyde dehydrogenase family
ECO111_RS08890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ECO111_RS08895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECO111_RS08900	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ECO111_RS08905	COG1842	Phage shock protein A
ECO111_RS08915	COG1983	PspC domain protein
ECO111_RS08925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECO111_RS08935	COG1653	transport
ECO111_RS08940	COG1175	transmembrane transport
ECO111_RS08945	COG0395	ABC-type sugar transport system, permease component
ECO111_RS08950	COG1063	alcohol dehydrogenase
ECO111_RS08955	COG1082	Xylose isomerase domain protein TIM barrel
ECO111_RS08960	COG0673	inositol 2-dehydrogenase activity
ECO111_RS08970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECO111_RS08975	COG3842	ATPase activity
ECO111_RS08985	COG1609	Transcriptional regulator
ECO111_RS08990	COG3106	COG3106 Predicted ATPase
ECO111_RS09000	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ECO111_RS09005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ECO111_RS09010	COG4948	Mandelate Racemase Muconate Lactonizing
ECO111_RS09015	COG2866	Carboxypeptidase
ECO111_RS09020	COG0702	epimerase
ECO111_RS09025	COG1073	alpha beta
ECO111_RS09030	COG1073	alpha beta
ECO111_RS09035	COG0583	DNA-binding transcription factor activity
ECO111_RS09040	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ECO111_RS09045	COG4166	transmembrane transport
ECO111_RS09050	COG0668	transmembrane transport
ECO111_RS09055	COG3182	Iron-regulated membrane protein
ECO111_RS09060	COG0589	response to stress
ECO111_RS09065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECO111_RS09070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECO111_RS09075	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ECO111_RS09085	COG1473	amidohydrolase
ECO111_RS09090	COG1473	amidohydrolase
ECO111_RS09095	COG0583	DNA-binding transcription factor activity
ECO111_RS09100	COG2840	Smr protein MutS2
ECO111_RS09105	COG3706	GGDEF domain
ECO111_RS09120	COG0513	Belongs to the DEAD box helicase family
ECO111_RS09130	COG0582	viral genome integration into host DNA
ECO111_RS09285	COG2032	superoxide dismutase activity
ECO111_RS09300	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECO111_RS09325	COG0589	response to stress
ECO111_RS09330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECO111_RS09335	COG0674	pyruvate-flavodoxin oxidoreductase activity
ECO111_RS09335	COG1013	pyruvate-flavodoxin oxidoreductase activity
ECO111_RS09335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECO111_RS09335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ECO111_RS09340	COG3042	response to heat
ECO111_RS09345	COG3187	Heat shock protein
ECO111_RS09350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECO111_RS09355	COG2911	Protein conserved in bacteria
ECO111_RS09365	COG3784	Protein of unknown function (DUF1318)
ECO111_RS09370	COG2207	Transcriptional regulator
ECO111_RS09380	COG3733	amine oxidase
ECO111_RS09385	COG1012	belongs to the aldehyde dehydrogenase family
ECO111_RS09385	COG2030	dehydratase
ECO111_RS09390	COG3396	Phenylacetate-CoA oxygenase
ECO111_RS09395	COG3460	Phenylacetate-CoA oxygenase
ECO111_RS09400	COG3396	Phenylacetate-CoA oxygenase
ECO111_RS09405	COG2151	metal-sulfur cluster biosynthetic enzyme
ECO111_RS09410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECO111_RS09415	COG1024	Enoyl-CoA hydratase
ECO111_RS09420	COG1024	Enoyl-CoA hydratase
ECO111_RS09425	COG1250	3-hydroxyacyl-CoA dehydrogenase
ECO111_RS09430	COG2050	protein possibly involved in aromatic compounds catabolism
ECO111_RS09435	COG0183	Belongs to the thiolase family
ECO111_RS09440	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ECO111_RS09445	COG3327	negative regulation of DNA-templated transcription, initiation
ECO111_RS09450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECO111_RS09455	COG0667	Aldo Keto reductase
ECO111_RS09465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECO111_RS09470	COG4589	Belongs to the CDS family
ECO111_RS09475	COG2267	carboxylic ester hydrolase activity
ECO111_RS09480	COG2453	phosphatase
ECO111_RS09480	COG0671	phosphoesterase, PA-phosphatase related
ECO111_RS09490	COG1643	Atp-dependent helicase
ECO111_RS09495	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECO111_RS09505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECO111_RS09510	COG3038	cytochrome b561
ECO111_RS09525	COG0840	transmembrane signaling receptor activity
ECO111_RS09530	COG0583	DNA-binding transcription factor activity
ECO111_RS09535	COG5383	Protein conserved in bacteria
ECO111_RS09550	COG2841	Protein conserved in bacteria
ECO111_RS09555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECO111_RS09560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECO111_RS09565	COG1275	C4-dicarboxylate transporter malic acid transport protein
ECO111_RS09570	COG0500	methyltransferase
ECO111_RS09585	COG0675	Transposase, IS605 OrfB family
ECO111_RS09590	COG3135	benzoate transporter
ECO111_RS09595	COG1396	sequence-specific DNA binding
ECO111_RS09600	COG0826	peptidase U32
ECO111_RS09610	COG1724	mRNA binding
ECO111_RS09615	COG1598	PFAM Uncharacterised protein family UPF0150
ECO111_RS09620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECO111_RS09625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECO111_RS09630	COG3842	ATPase activity
ECO111_RS09635	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECO111_RS09640	COG1177	transmembrane transport
ECO111_RS09670	COG3238	Protein conserved in bacteria
ECO111_RS09675	COG1247	-acetyltransferase
ECO111_RS09680	COG2130	NADP-dependent
ECO111_RS09685	COG1802	Transcriptional regulator
ECO111_RS09690	COG4772	TonB-dependent receptor
ECO111_RS09695	COG3391	amine dehydrogenase activity
ECO111_RS09705	COG0625	glutathione transferase activity
ECO111_RS09720	COG3209	COG3209 Rhs family protein
ECO111_RS09735	COG5433	transposase activity
ECO111_RS09750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ECO111_RS09755	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ECO111_RS09760	COG0384	phenazine biosynthesis protein PhzF
ECO111_RS09765	COG2181	nitrate reductase activity
ECO111_RS09770	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECO111_RS09775	COG1140	nitrate reductase beta subunit
ECO111_RS09780	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ECO111_RS09785	COG2223	nitrite transmembrane transporter activity
ECO111_RS09790	COG4886	Leucine-rich repeat (LRR) protein
ECO111_RS09795	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECO111_RS09800	COG0697	spore germination
ECO111_RS09805	COG0243	molybdopterin cofactor binding
ECO111_RS09805	COG3383	formate dehydrogenase (NAD+) activity
ECO111_RS09810	COG3383	formate dehydrogenase (NAD+) activity
ECO111_RS09810	COG0243	molybdopterin cofactor binding
ECO111_RS09815	COG0437	4 iron, 4 sulfur cluster binding
ECO111_RS09820	COG2864	formate dehydrogenase
ECO111_RS09825	COG3093	addiction module antidote protein HigA
ECO111_RS09830	COG1064	alcohol dehydrogenase
ECO111_RS09850	COG1764	response to oxidative stress
ECO111_RS09855	COG4608	Belongs to the ABC transporter superfamily
ECO111_RS09860	COG0444	Belongs to the ABC transporter superfamily
ECO111_RS09865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECO111_RS09870	COG0601	transmembrane transport
ECO111_RS09875	COG0747	negative chemotaxis
ECO111_RS09880	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ECO111_RS09885	COG2199	diguanylate cyclase activity
ECO111_RS09885	COG2202	Pas domain
ECO111_RS09885	COG2200	EAL domain
ECO111_RS09895	COG1649	PFAM Uncharacterised BCR, COG1649
ECO111_RS09900	COG0531	amino acid
ECO111_RS09905	COG0076	glutamate decarboxylase activity
ECO111_RS09915	COG0612	Peptidase, M16
ECO111_RS09920	COG4771	TonB-dependent receptor
ECO111_RS09925	COG4178	(ABC) transporter
ECO111_RS09930	COG0641	radical SAM
ECO111_RS09935	COG3119	arylsulfatase activity
ECO111_RS09940	COG2207	Transcriptional regulator
ECO111_RS09950	COG0243	molybdopterin cofactor binding
ECO111_RS09955	COG3539	Fimbrial protein
ECO111_RS09960	COG3539	Fimbrial protein
ECO111_RS09965	COG3539	Fimbrial protein
ECO111_RS09970	COG3188	usher protein
ECO111_RS09980	COG3539	Fimbrial protein
ECO111_RS09985	COG4977	sequence-specific DNA binding
ECO111_RS09990	COG3550	peptidyl-serine autophosphorylation
ECO111_RS09995	COG1396	sequence-specific DNA binding
ECO111_RS10005	COG3210	domain, Protein
ECO111_RS10005	COG2911	Protein conserved in bacteria
ECO111_RS10020	COG3210	domain, Protein
ECO111_RS10020	COG2911	Protein conserved in bacteria
ECO111_RS10070	COG3781	membrane
ECO111_RS10080	COG2199	diguanylate cyclase activity
ECO111_RS10090	COG2066	Belongs to the glutaminase family
ECO111_RS10095	COG1012	belongs to the aldehyde dehydrogenase family
ECO111_RS10100	COG0583	DNA-binding transcription factor activity
ECO111_RS10125	COG1846	Transcriptional regulator
ECO111_RS10130	COG4977	sequence-specific DNA binding
ECO111_RS10140	COG2723	6-phospho-beta-galactosidase activity
ECO111_RS10150	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECO111_RS10155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECO111_RS10165	COG2188	Transcriptional regulator
ECO111_RS10170	COG0697	spore germination
ECO111_RS10175	COG2814	Major facilitator Superfamily
ECO111_RS10185	COG3706	GGDEF domain
ECO111_RS10190	COG3111	PFAM Bacterial OB fold (BOF) protein
ECO111_RS10195	COG1546	Belongs to the CinA family
ECO111_RS10200	COG0339	signal peptide processing
ECO111_RS10205	COG4221	oxidoreductase activity
ECO111_RS10210	COG1802	Transcriptional regulator
ECO111_RS10220	COG0246	Mannitol dehydrogenase
ECO111_RS10225	COG0477	Major facilitator Superfamily
ECO111_RS10245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ECO111_RS10305	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECO111_RS10310	COG1403	HNH endonuclease
ECO111_RS10340	COG1846	Transcriptional regulator
ECO111_RS10365	COG1396	sequence-specific DNA binding
ECO111_RS10400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS10410	COG0582	viral genome integration into host DNA
ECO111_RS10415	COG3047	cAMP biosynthetic process
ECO111_RS10430	COG1607	acyl-coa hydrolase
ECO111_RS10470	COG3328	transposase activity
ECO111_RS10485	COG0582	viral genome integration into host DNA
ECO111_RS10495	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECO111_RS10650	COG3772	lysozyme
ECO111_RS10685	COG1396	sequence-specific DNA binding
ECO111_RS10715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS10725	COG0582	viral genome integration into host DNA
ECO111_RS10730	COG1063	alcohol dehydrogenase
ECO111_RS10735	COG4948	Mandelate Racemase Muconate Lactonizing
ECO111_RS10750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECO111_RS10770	COG0243	molybdopterin cofactor binding
ECO111_RS10775	COG0437	4 iron, 4 sulfur cluster binding
ECO111_RS10780	COG3302	dmso reductase anchor subunit
ECO111_RS10785	COG3381	protein complex oligomerization
ECO111_RS10795	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECO111_RS10800	COG1940	carbohydrate kinase activity
ECO111_RS10805	COG0583	DNA-binding transcription factor activity
ECO111_RS10810	COG2814	Major facilitator Superfamily
ECO111_RS10825	COG3591	Belongs to the peptidase S1B family
ECO111_RS10840	COG0628	permease
ECO111_RS10845	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ECO111_RS10850	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ECO111_RS10860	COG0531	amino acid
ECO111_RS10870	COG3136	membrane protein required for alginate biosynthesis
ECO111_RS10875	COG0745	RESPONSE REGULATOR receiver
ECO111_RS10880	COG2205	protein histidine kinase activity
ECO111_RS10890	COG0114	fumarate hydratase activity
ECO111_RS10895	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECO111_RS10895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECO111_RS10900	COG1482	cell wall glycoprotein biosynthetic process
ECO111_RS10905	COG5339	Protein conserved in bacteria
ECO111_RS10920	COG3250	beta-galactosidase activity
ECO111_RS10925	COG1309	transcriptional regulator
ECO111_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS10935	COG1609	Transcriptional regulator
ECO111_RS10940	COG1263	PTS System
ECO111_RS10940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS10945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECO111_RS10955	COG0673	inositol 2-dehydrogenase activity
ECO111_RS10995	COG4659	FMN binding
ECO111_RS11005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ECO111_RS11015	COG3104	oligopeptide transport
ECO111_RS11020	COG0625	glutathione transferase activity
ECO111_RS11025	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ECO111_RS11040	COG3895	Periplasmic Protein
ECO111_RS11050	COG3133	Outer membrane lipoprotein
ECO111_RS11065	COG1566	PFAM secretion protein HlyD family protein
ECO111_RS11070	COG1289	transmembrane transporter activity
ECO111_RS11075	COG2032	superoxide dismutase activity
ECO111_RS11080	COG4989	oxidoreductase activity
ECO111_RS11085	COG3313	Fe-S protein
ECO111_RS11090	COG1309	transcriptional regulator
ECO111_RS11095	COG1902	pentaerythritol trinitrate reductase activity
ECO111_RS11100	COG0346	lactoylglutathione lyase activity
ECO111_RS11110	COG1201	RNA secondary structure unwinding
ECO111_RS11115	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ECO111_RS11120	COG0791	NLP P60 protein
ECO111_RS11125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ECO111_RS11130	COG2814	Major facilitator Superfamily
ECO111_RS11145	COG0583	DNA-binding transcription factor activity
ECO111_RS11150	COG2814	Major facilitator Superfamily
ECO111_RS11155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ECO111_RS11160	COG0307	riboflavin synthase, alpha
ECO111_RS11170	COG3468	outer membrane autotransporter barrel domain protein
ECO111_RS11190	COG4529	Protein conserved in bacteria
ECO111_RS11200	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ECO111_RS11205	COG0437	4 iron, 4 sulfur cluster binding
ECO111_RS11215	COG2414	aldehyde ferredoxin oxidoreductase
ECO111_RS11220	COG0437	4 iron, 4 sulfur cluster binding
ECO111_RS11230	COG0469	pyruvate kinase activity
ECO111_RS11235	COG4238	major outer membrane lipoprotein
ECO111_RS11240	COG1376	ErfK ybiS ycfS ynhG family protein
ECO111_RS11255	COG0719	Fe-S assembly protein
ECO111_RS11260	COG0396	ATPase activity
ECO111_RS11265	COG0719	Fe-S assembly protein
ECO111_RS11270	COG0316	Belongs to the HesB IscA family
ECO111_RS11280	COG2050	protein possibly involved in aromatic compounds catabolism
ECO111_RS11285	COG0277	FAD linked oxidase domain protein
ECO111_RS11285	COG0247	lactate metabolic process
ECO111_RS11290	COG0628	permease
ECO111_RS11300	COG0738	Major facilitator superfamily
ECO111_RS11305	COG2271	Major facilitator Superfamily
ECO111_RS11325	COG1960	acyl-CoA dehydrogenase activity
ECO111_RS11330	COG2207	Transcriptional regulator
ECO111_RS11330	COG1917	Cupin 2, conserved barrel domain protein
ECO111_RS11340	COG2086	electron transfer activity
ECO111_RS11345	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ECO111_RS11350	COG0644	oxidoreductase
ECO111_RS11355	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECO111_RS11360	COG0318	PFAM AMP-dependent synthetase and ligase
ECO111_RS11365	COG0574	Belongs to the PEP-utilizing enzyme family
ECO111_RS11365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECO111_RS11380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECO111_RS11385	COG4256	Hemin uptake protein
ECO111_RS11395	COG2200	EAL domain
ECO111_RS11400	COG0791	NLP P60 protein
ECO111_RS11410	COG0386	Belongs to the glutathione peroxidase family
ECO111_RS11425	COG4974	Belongs to the 'phage' integrase family
ECO111_RS11480	COG4695	Portal protein
ECO111_RS11560	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECO111_RS11565	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECO111_RS11675	COG3137	Salt-induced outer membrane protein
ECO111_RS11680	COG1105	Belongs to the carbohydrate kinase PfkB family
ECO111_RS11690	COG3001	Fructosamine kinase
ECO111_RS11700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECO111_RS11705	COG1988	membrane-bound metal-dependent
ECO111_RS11710	COG1823	symporter activity
ECO111_RS11730	COG0753	catalase activity
ECO111_RS11740	COG1486	melibiose metabolic process
ECO111_RS11745	COG2169	Transcriptional regulator
ECO111_RS11745	COG1917	Cupin 2, conserved barrel domain protein
ECO111_RS11750	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECO111_RS11755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECO111_RS11760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECO111_RS11765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECO111_RS11780	COG0322	excinuclease ABC activity
ECO111_RS11790	COG3678	ATP-independent chaperone mediated protein folding
ECO111_RS11820	COG0708	Exodeoxyribonuclease III
ECO111_RS11825	COG0398	Pfam SNARE associated Golgi protein
ECO111_RS11835	COG0398	Pfam SNARE associated Golgi protein
ECO111_RS11840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECO111_RS11845	COG4134	Bacterial extracellular solute-binding protein
ECO111_RS11850	COG4135	transport system, permease component
ECO111_RS11855	COG4136	ATPase activity
ECO111_RS11860	COG2897	thiosulfate sulfurtransferase activity
ECO111_RS11865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECO111_RS11870	COG0494	nUDIX hydrolase
ECO111_RS11880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ECO111_RS11890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECO111_RS11905	COG0778	Nitroreductase
ECO111_RS11915	COG0616	signal peptide processing
ECO111_RS11920	COG0252	asparaginase activity
ECO111_RS11925	COG1335	isochorismatase
ECO111_RS11930	COG3139	Protein of unknown function (DUF1315)
ECO111_RS11940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECO111_RS11945	COG0676	glucose-6-phosphate 1-epimerase activity
ECO111_RS11950	COG0656	L-ascorbic acid biosynthetic process
ECO111_RS11955	COG3713	MltA-interacting MipA family protein
ECO111_RS11960	COG2766	serine protein kinase
ECO111_RS11970	COG2199	diguanylate cyclase activity
ECO111_RS11975	COG2199	diguanylate cyclase activity
ECO111_RS11980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECO111_RS11995	COG2207	Transcriptional regulator
ECO111_RS12000	COG2807	transmembrane transport
ECO111_RS12005	COG3189	MarR family transcriptional regulator
ECO111_RS12010	COG3042	response to heat
ECO111_RS12015	COG2203	Gaf domain
ECO111_RS12015	COG2199	diguanylate cyclase activity
ECO111_RS12025	COG2261	transglycosylase associated protein
ECO111_RS12040	COG0675	Transposase, IS605 OrfB family
ECO111_RS12055	COG3615	Tellurite resistance protein tehB
ECO111_RS12065	COG0583	DNA-binding transcription factor activity
ECO111_RS12070	COG0473	3-isopropylmalate dehydrogenase activity
ECO111_RS12075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECO111_RS12080	COG4638	Rieske (2fe-2S)
ECO111_RS12085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECO111_RS12090	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ECO111_RS12095	COG0318	PFAM AMP-dependent synthetase and ligase
ECO111_RS12100	COG3065	identical protein binding
ECO111_RS12105	COG1214	PFAM Peptidase M22, glycoprotease
ECO111_RS12110	COG1199	ATP-dependent helicase activity
ECO111_RS12115	COG0251	oxidation-reduction process
ECO111_RS12130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECO111_RS12140	COG1760	l-serine dehydratase
ECO111_RS12145	COG2200	EAL domain
ECO111_RS12150	COG1253	flavin adenine dinucleotide binding
ECO111_RS12160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS12160	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS12165	COG3715	PTS system
ECO111_RS12170	COG3716	PTS system mannose fructose sorbose family IID component
ECO111_RS12190	COG2226	methyltransferase
ECO111_RS12225	COG1414	Transcriptional regulator
ECO111_RS12230	COG2814	Major facilitator Superfamily
ECO111_RS12240	COG0793	Belongs to the peptidase S41A family
ECO111_RS12250	COG1956	GAF domain-containing protein
ECO111_RS12255	COG2995	paraquat-inducible protein a
ECO111_RS12260	COG3008	intermembrane lipid transfer
ECO111_RS12280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECO111_RS12295	COG1276	copper resistance
ECO111_RS12300	COG2372	response to copper ion
ECO111_RS12310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECO111_RS12315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS12320	COG1770	oligopeptidase
ECO111_RS12325	COG2979	Protein of unknown function (DUF533)
ECO111_RS12340	COG3141	response to X-ray
ECO111_RS12350	COG0800	Aldolase
ECO111_RS12355	COG0129	dihydroxy-acid dehydratase activity
ECO111_RS12360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ECO111_RS12370	COG1737	Transcriptional regulator
ECO111_RS12375	COG0469	pyruvate kinase activity
ECO111_RS12400	COG3833	ABC-type maltose transport systems, permease component
ECO111_RS12405	COG1175	transmembrane transport
ECO111_RS12410	COG2182	Extracellular solute-binding protein
ECO111_RS12420	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ECO111_RS12430	COG3842	ATPase activity
ECO111_RS12450	COG1560	Kdo2-lipid A biosynthetic process
ECO111_RS12455	COG0739	heme binding
ECO111_RS12460	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ECO111_RS12470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECO111_RS12495	COG0217	transcriptional regulatory protein
ECO111_RS12500	COG0494	nUDIX hydrolase
ECO111_RS12510	COG1335	isochorismatase
ECO111_RS12530	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECO111_RS12545	COG2032	superoxide dismutase activity
ECO111_RS12665	COG3772	lysozyme
ECO111_RS12740	COG1403	HNH endonuclease
ECO111_RS12750	COG0305	Participates in initiation and elongation during chromosome replication
ECO111_RS12755	COG1484	DNA-dependent DNA replication
ECO111_RS12785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECO111_RS12830	COG0582	viral genome integration into host DNA
ECO111_RS12835	COG1801	Protein of unknown function DUF72
ECO111_RS12840	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ECO111_RS12855	COG0243	molybdopterin cofactor binding
ECO111_RS12860	COG3005	denitrification pathway
ECO111_RS12870	COG3102	Protein conserved in bacteria
ECO111_RS12880	COG3755	Protein conserved in bacteria
ECO111_RS12890	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ECO111_RS12895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ECO111_RS12900	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ECO111_RS12905	COG0745	RESPONSE REGULATOR receiver
ECO111_RS12910	COG2201	protein-glutamate methylesterase activity
ECO111_RS12915	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ECO111_RS12920	COG0840	transmembrane signaling receptor activity
ECO111_RS12925	COG0840	transmembrane signaling receptor activity
ECO111_RS12930	COG0835	chemotaxis
ECO111_RS12935	COG2198	Histidine kinase
ECO111_RS12935	COG0643	Histidine kinase
ECO111_RS12940	COG1360	Flagellar Motor Protein
ECO111_RS12945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ECO111_RS12960	COG0589	response to stress
ECO111_RS12970	COG1877	trehalose-phosphatase activity
ECO111_RS12975	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECO111_RS12980	COG1129	ABC transporter
ECO111_RS12985	COG1879	ABC-type sugar transport system periplasmic component
ECO111_RS12990	COG1528	Iron-storage protein
ECO111_RS13010	COG1528	Iron-storage protein
ECO111_RS13020	COG0814	amino acid
ECO111_RS13025	COG3318	Belongs to the UPF0149 family
ECO111_RS13025	COG3012	SEC-C Motif Domain Protein
ECO111_RS13055	COG2197	response regulator
ECO111_RS13070	COG2197	response regulator
ECO111_RS13075	COG1126	abc transporter atp-binding protein
ECO111_RS13080	COG0765	amino acid transport
ECO111_RS13090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECO111_RS13100	COG1191	sigma factor activity
ECO111_RS13125	COG1516	flagellar protein fliS
ECO111_RS13135	COG0366	Alpha amylase catalytic
ECO111_RS13145	COG2391	methyltransferase activity
ECO111_RS13150	COG0425	Belongs to the sulfur carrier protein TusA family
ECO111_RS13155	COG2135	peptidase activity
ECO111_RS13160	COG0675	Transposase, IS605 OrfB family
ECO111_RS13175	COG2207	Transcriptional regulator
ECO111_RS13180	COG1881	PFAM PEBP family protein
ECO111_RS13185	COG2076	Multidrug Resistance protein
ECO111_RS13200	COG1766	The M ring may be actively involved in energy transduction
ECO111_RS13205	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECO111_RS13210	COG1317	bacterial-type flagellum organization
ECO111_RS13215	COG1157	protein secretion by the type III secretion system
ECO111_RS13220	COG2882	bacterial-type flagellum organization
ECO111_RS13225	COG3144	bacterial-type flagellum assembly
ECO111_RS13230	COG1580	Controls the rotational direction of flagella during chemotaxis
ECO111_RS13235	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECO111_RS13240	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECO111_RS13245	COG3190	flagellar
ECO111_RS13250	COG1338	Plays a role in the flagellum-specific transport system
ECO111_RS13255	COG1987	bacterial-type flagellum assembly
ECO111_RS13260	COG1684	flagellar biosynthetic protein fliR
ECO111_RS13265	COG2197	response regulator
ECO111_RS13285	COG3706	GGDEF domain
ECO111_RS13290	COG5475	Uncharacterized small protein (DUF2158)
ECO111_RS13295	COG2354	Protein conserved in bacteria
ECO111_RS13300	COG0697	spore germination
ECO111_RS13305	COG3727	T/G mismatch-specific endonuclease activity
ECO111_RS13310	COG0270	DNA (cytosine-5-)-methyltransferase activity
ECO111_RS13315	COG1418	mRNA catabolic process
ECO111_RS13330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECO111_RS13345	COG2205	protein histidine kinase activity
ECO111_RS13350	COG0745	RESPONSE REGULATOR receiver
ECO111_RS13355	COG2351	hydroxyisourate hydrolase activity
ECO111_RS13370	COG3443	Belongs to the bacterial solute-binding protein 9 family
ECO111_RS13375	COG3038	cytochrome b561
ECO111_RS13395	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECO111_RS13500	COG4220	transposase activity
ECO111_RS13530	COG3772	lysozyme
ECO111_RS13575	COG3436	PFAM IS66 Orf2 family protein
ECO111_RS13580	COG4372	Transposase
ECO111_RS13600	COG2207	Transcriptional regulator
ECO111_RS13615	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECO111_RS13620	COG1403	HNH endonuclease
ECO111_RS13630	COG3111	PFAM Bacterial OB fold (BOF) protein
ECO111_RS13665	COG1846	Transcriptional regulator
ECO111_RS13670	COG1484	DNA-dependent DNA replication
ECO111_RS13720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS13735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS13760	COG0582	viral genome integration into host DNA
ECO111_RS13785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ECO111_RS13790	COG0217	transcriptional regulatory protein
ECO111_RS13810	COG0583	DNA-binding transcription factor activity
ECO111_RS13815	COG0583	DNA-binding transcription factor activity
ECO111_RS13825	COG1376	ErfK ybiS ycfS ynhG family protein
ECO111_RS13840	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ECO111_RS13895	COG2003	Belongs to the UPF0758 family
ECO111_RS13925	COG4372	Transposase
ECO111_RS13960	COG1686	Belongs to the peptidase S11 family
ECO111_RS14080	COG1783	phage Terminase large subunit
ECO111_RS14110	COG3646	Phage regulatory protein
ECO111_RS14145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECO111_RS14190	COG0305	Participates in initiation and elongation during chromosome replication
ECO111_RS14305	COG0582	viral genome integration into host DNA
ECO111_RS14310	COG2925	Exonuclease
ECO111_RS14315	COG0425	Belongs to the sulfur carrier protein TusA family
ECO111_RS14320	COG2391	methyltransferase activity
ECO111_RS14325	COG0531	amino acid
ECO111_RS14330	COG0583	DNA-binding transcription factor activity
ECO111_RS14335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECO111_RS14340	COG4115	mRNA cleavage
ECO111_RS14345	COG2161	toxin-antitoxin pair type II binding
ECO111_RS14370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ECO111_RS14405	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ECO111_RS14415	COG1216	Glycosyl transferase, family 2
ECO111_RS14415	COG0463	Glycosyl transferase, family 2
ECO111_RS14440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECO111_RS14450	COG1051	belongs to the nudix hydrolase family
ECO111_RS14455	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ECO111_RS14460	COG0438	transferase activity, transferring glycosyl groups
ECO111_RS14485	COG2826	transposase and inactivated derivatives, IS30 family
ECO111_RS14490	COG2963	transposase activity
ECO111_RS14495	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ECO111_RS14500	COG0110	maltose O-acetyltransferase activity
ECO111_RS14505	COG1216	Glycosyl transferase, family 2
ECO111_RS14515	COG0438	transferase activity, transferring glycosyl groups
ECO111_RS14520	COG0438	transferase activity, transferring glycosyl groups
ECO111_RS14525	COG1045	serine acetyltransferase
ECO111_RS14530	COG0463	Glycosyl transferase, family 2
ECO111_RS14535	COG0489	protein tyrosine kinase activity
ECO111_RS14535	COG3206	protein involved in exopolysaccharide biosynthesis
ECO111_RS14540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ECO111_RS14550	COG1253	flavin adenine dinucleotide binding
ECO111_RS14555	COG2982	Protein involved in outer membrane biogenesis
ECO111_RS14565	COG0572	uridine kinase
ECO111_RS14570	COG5001	Diguanylate cyclase
ECO111_RS14570	COG3447	MASE1 domain protein
ECO111_RS14570	COG5002	protein histidine kinase activity
ECO111_RS14575	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ECO111_RS14580	COG0443	Heat shock 70 kDa protein
ECO111_RS14585	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
ECO111_RS14590	COG0631	protein serine/threonine phosphatase activity
ECO111_RS14595	COG4245	von Willebrand factor, type A
ECO111_RS14620	COG2205	protein histidine kinase activity
ECO111_RS14625	COG0745	RESPONSE REGULATOR receiver
ECO111_RS14635	COG3609	addiction module antidote protein, CC2985 family
ECO111_RS14645	COG0826	peptidase U32
ECO111_RS14670	COG1063	alcohol dehydrogenase
ECO111_RS14675	COG3775	system Galactitol-specific IIC component
ECO111_RS14680	COG3414	Phosphotransferase system galactitol-specific IIB component
ECO111_RS14685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS14700	COG1830	Aldolase
ECO111_RS14705	COG2211	Major facilitator Superfamily
ECO111_RS14710	COG1397	ADP-ribosylglycohydrolase
ECO111_RS14715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECO111_RS14720	COG2188	Transcriptional regulator
ECO111_RS14725	COG3757	hydrolase, family 25
ECO111_RS14730	COG0351	phosphomethylpyrimidine kinase
ECO111_RS14745	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ECO111_RS14750	COG5455	response to cobalt ion
ECO111_RS14755	COG3539	Fimbrial protein
ECO111_RS14760	COG3188	usher protein
ECO111_RS14765	COG3121	Chaperone
ECO111_RS14770	COG3539	Fimbrial protein
ECO111_RS14785	COG0489	protein tyrosine kinase activity
ECO111_RS14800	COG3831	ATPase activity
ECO111_RS14805	COG3831	ATPase activity
ECO111_RS14825	COG0714	Associated with various cellular activities
ECO111_RS14830	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ECO111_RS14835	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ECO111_RS14840	COG4715	Zinc finger, swim domain protein
ECO111_RS14845	COG4808	Protein conserved in bacteria
ECO111_RS14850	COG4807	Protein conserved in bacteria
ECO111_RS14855	COG3279	Response regulator of the LytR AlgR family
ECO111_RS14860	COG3275	phosphorelay sensor kinase activity
ECO111_RS14865	COG0789	Transcriptional regulator
ECO111_RS14875	COG1174	glycine betaine transport
ECO111_RS14880	COG1125	glycine betaine transport
ECO111_RS14885	COG1174	glycine betaine transport
ECO111_RS14890	COG1732	Glycine betaine
ECO111_RS14895	COG1472	Belongs to the glycosyl hydrolase 3 family
ECO111_RS14900	COG0277	FAD linked oxidase domain protein
ECO111_RS14905	COG1686	Belongs to the peptidase S11 family
ECO111_RS14915	COG0586	Pfam SNARE associated Golgi protein
ECO111_RS14920	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS14935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECO111_RS14945	COG1346	cytolysis
ECO111_RS14955	COG2949	membrane
ECO111_RS14965	COG0493	'glutamate synthase
ECO111_RS14970	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ECO111_RS14970	COG0167	dihydroorotate dehydrogenase activity
ECO111_RS14975	COG4211	Belongs to the binding-protein-dependent transport system permease family
ECO111_RS14980	COG1129	ABC transporter
ECO111_RS14985	COG1879	ABC-type sugar transport system periplasmic component
ECO111_RS14990	COG1609	Transcriptional regulator
ECO111_RS15000	COG2311	Membrane
ECO111_RS15020	COG4771	TonB-dependent receptor
ECO111_RS15030	COG0833	amino acid
ECO111_RS15035	COG0583	DNA-binding transcription factor activity
ECO111_RS15040	COG2855	membrane
ECO111_RS15050	COG1522	sequence-specific DNA binding
ECO111_RS15050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECO111_RS15055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECO111_RS15055	COG1522	sequence-specific DNA binding
ECO111_RS15070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECO111_RS15075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECO111_RS15080	COG2313	pseudouridylate synthase activity
ECO111_RS15085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECO111_RS15090	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ECO111_RS15090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS15090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS15095	COG1105	Belongs to the carbohydrate kinase PfkB family
ECO111_RS15100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS15100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS15105	COG2814	Major facilitator Superfamily
ECO111_RS15120	COG0246	Mannitol dehydrogenase
ECO111_RS15125	COG0523	cobalamin synthesis protein
ECO111_RS15130	COG0671	phosphoesterase, PA-phosphatase related
ECO111_RS15135	COG0791	NLP P60 protein
ECO111_RS15140	COG2200	EAL domain
ECO111_RS15145	COG4166	transmembrane transport
ECO111_RS15150	COG4174	ABC transporter (Permease)
ECO111_RS15155	COG4239	(ABC) transporter, permease
ECO111_RS15160	COG4172	Belongs to the ABC transporter superfamily
ECO111_RS15170	COG2814	Major facilitator Superfamily
ECO111_RS15175	COG1187	pseudouridine synthase activity
ECO111_RS15180	COG1061	Type III restriction enzyme res subunit
ECO111_RS15200	COG3083	sulfuric ester hydrolase activity
ECO111_RS15210	COG0582	viral genome integration into host DNA
ECO111_RS15300	COG3468	outer membrane autotransporter barrel domain protein
ECO111_RS15315	COG2197	response regulator
ECO111_RS15320	COG3088	subunit of a heme lyase
ECO111_RS15320	COG4235	cytochrome complex assembly
ECO111_RS15325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECO111_RS15330	COG1138	Cytochrome C-type biogenesis protein
ECO111_RS15340	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECO111_RS15345	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECO111_RS15350	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECO111_RS15355	COG4133	protoheme IX ABC transporter activity
ECO111_RS15360	COG3005	denitrification pathway
ECO111_RS15365	COG3043	anaerobic respiration
ECO111_RS15370	COG0348	domain, Protein
ECO111_RS15375	COG0437	4 iron, 4 sulfur cluster binding
ECO111_RS15385	COG3062	negative regulation of establishment of protein localization
ECO111_RS15390	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS15390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS15410	COG4615	Cyclic peptide transporter
ECO111_RS15415	COG3145	DNA-N1-methyladenine dioxygenase activity
ECO111_RS15420	COG2169	Transcriptional regulator
ECO111_RS15420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECO111_RS15425	COG1477	protein flavinylation
ECO111_RS15430	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECO111_RS15445	COG0642	Histidine kinase
ECO111_RS15445	COG2198	Histidine kinase
ECO111_RS15450	COG2197	response regulator
ECO111_RS15455	COG0784	Response regulator, receiver
ECO111_RS15455	COG2205	protein histidine kinase activity
ECO111_RS15460	COG4676	Protein conserved in bacteria
ECO111_RS15465	COG5445	Predicted secreted protein (DUF2300)
ECO111_RS15470	COG2373	Large extracellular alpha-helical protein
ECO111_RS15495	COG3772	lysozyme
ECO111_RS15560	COG0582	viral genome integration into host DNA
ECO111_RS15565	COG3234	Protein of unknown function (DUF1175)
ECO111_RS15570	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
ECO111_RS15575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECO111_RS15585	COG3468	outer membrane autotransporter barrel domain protein
ECO111_RS15595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECO111_RS15600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECO111_RS15605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECO111_RS15610	COG3642	lipopolysaccharide core region biosynthetic process
ECO111_RS15615	COG0583	DNA-binding transcription factor activity
ECO111_RS15620	COG0584	glycerophosphoryl diester phosphodiesterase
ECO111_RS15625	COG2271	Major facilitator Superfamily
ECO111_RS15630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECO111_RS15640	COG0247	lactate metabolic process
ECO111_RS15645	COG5464	transposase or invertase
ECO111_RS15715	COG0318	PFAM AMP-dependent synthetase and ligase
ECO111_RS15725	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ECO111_RS15740	COG1169	isochorismate synthase
ECO111_RS15745	COG4575	ribosome binding
ECO111_RS15750	COG2153	protein acetylation
ECO111_RS15765	COG2304	oxidoreductase activity
ECO111_RS15770	COG2234	aminopeptidase activity
ECO111_RS15785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECO111_RS15790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECO111_RS15800	COG0839	Belongs to the complex I subunit 6 family
ECO111_RS15815	COG1034	ATP synthesis coupled electron transport
ECO111_RS15820	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ECO111_RS15825	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ECO111_RS15845	COG0583	DNA-binding transcription factor activity
ECO111_RS15850	COG0436	Aminotransferase
ECO111_RS15860	COG0490	domain, Protein
ECO111_RS15860	COG0471	metal ion transport
ECO111_RS15865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECO111_RS15885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECO111_RS15890	COG0857	belongs to the CobB CobQ family
ECO111_RS15890	COG0280	phosphate acetyltransferase
ECO111_RS15895	COG1288	antiporter activity
ECO111_RS15900	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ECO111_RS15905	COG0622	Phosphoesterase
ECO111_RS15910	COG0625	glutathione transferase activity
ECO111_RS15915	COG0625	glutathione transferase activity
ECO111_RS15920	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECO111_RS15925	COG1090	epimerase
ECO111_RS15930	COG5464	transposase or invertase
ECO111_RS15935	COG4598	ABC transporter
ECO111_RS15940	COG4160	amino acid transport
ECO111_RS15945	COG4215	(ABC) transporter
ECO111_RS15950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECO111_RS15955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECO111_RS15960	COG0163	prenyltransferase activity
ECO111_RS15965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ECO111_RS15970	COG1286	toxin biosynthetic process
ECO111_RS15975	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ECO111_RS15980	COG0285	dihydrofolate synthase activity
ECO111_RS15990	COG0586	Pfam SNARE associated Golgi protein
ECO111_RS16000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECO111_RS16015	COG2814	Major facilitator Superfamily
ECO111_RS16020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECO111_RS16035	COG3101	peptidyl-lysine hydroxylation
ECO111_RS16040	COG0730	response to heat
ECO111_RS16070	COG3539	Fimbrial protein
ECO111_RS16075	COG3539	Fimbrial protein
ECO111_RS16080	COG3539	Fimbrial protein
ECO111_RS16085	COG3121	Chaperone
ECO111_RS16090	COG3188	usher protein
ECO111_RS16095	COG3539	Fimbrial protein
ECO111_RS16100	COG2062	phosphohistidine phosphatase, SixA
ECO111_RS16115	COG3691	Protein conserved in bacteria
ECO111_RS16120	COG2067	long-chain fatty acid transport protein
ECO111_RS16130	COG2853	Lipoprotein
ECO111_RS16135	COG2116	formate transmembrane transporter activity
ECO111_RS16170	COG2610	gluconate transmembrane transporter activity
ECO111_RS16180	COG0477	Major facilitator Superfamily
ECO111_RS16185	COG1566	PFAM secretion protein HlyD family protein
ECO111_RS16190	COG2197	response regulator
ECO111_RS16195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECO111_RS16195	COG2198	Histidine kinase
ECO111_RS16195	COG2205	protein histidine kinase activity
ECO111_RS16195	COG0784	Response regulator, receiver
ECO111_RS16200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ECO111_RS16205	COG0679	Auxin Efflux Carrier
ECO111_RS16210	COG0028	Belongs to the TPP enzyme family
ECO111_RS16240	COG1560	Kdo2-lipid A biosynthetic process
ECO111_RS16245	COG0436	Aminotransferase
ECO111_RS16250	COG3275	phosphorelay sensor kinase activity
ECO111_RS16260	COG2207	Transcriptional regulator
ECO111_RS16270	COG1363	Peptidase, m42
ECO111_RS16275	COG0006	proline dipeptidase activity
ECO111_RS16280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS16285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS16315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECO111_RS16320	COG2200	EAL domain
ECO111_RS16320	COG2199	diguanylate cyclase activity
ECO111_RS16335	COG3415	Transposase
ECO111_RS16340	COG3415	Transposase
ECO111_RS16370	COG0583	DNA-binding transcription factor activity
ECO111_RS16380	COG2211	Major facilitator Superfamily
ECO111_RS16385	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ECO111_RS16395	COG0583	DNA-binding transcription factor activity
ECO111_RS16400	COG0385	Bile acid
ECO111_RS16405	COG3530	Putative quorum-sensing-regulated virulence factor
ECO111_RS16425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECO111_RS16430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS16435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECO111_RS16440	COG2190	(PTS) system
ECO111_RS16455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECO111_RS16460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ECO111_RS16465	COG4208	sulfate ABC transporter
ECO111_RS16470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ECO111_RS16475	COG4150	thiosulfate binding
ECO111_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS16495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS16495	COG1263	PTS System
ECO111_RS16500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECO111_RS16505	COG2837	iron assimilation
ECO111_RS16525	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECO111_RS16535	COG2207	Transcriptional regulator
ECO111_RS16540	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ECO111_RS16545	COG4816	utilization protein
ECO111_RS16555	COG4303	Ethanolamine ammonia lyase large subunit
ECO111_RS16560	COG4819	ethanolamine utilization protein
ECO111_RS16565	COG3192	ethanolamine utilization protein
ECO111_RS16570	COG1454	alcohol dehydrogenase
ECO111_RS16575	COG4820	ethanolamine utilization protein (EutJ)
ECO111_RS16580	COG1012	belongs to the aldehyde dehydrogenase family
ECO111_RS16585	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ECO111_RS16590	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ECO111_RS16595	COG0280	phosphate acetyltransferase
ECO111_RS16600	COG4812	Cobalamin adenosyltransferase
ECO111_RS16605	COG4766	ethanolamine catabolic process
ECO111_RS16610	COG4917	ethanolamine utilization protein
ECO111_RS16615	COG4810	utilization protein
ECO111_RS16620	COG0280	phosphate acetyltransferase
ECO111_RS16620	COG0281	malic enzyme
ECO111_RS16625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECO111_RS16630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECO111_RS16635	COG5342	invasion associated locus B
ECO111_RS16645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS16645	COG0493	'glutamate synthase
ECO111_RS16650	COG3850	Histidine kinase
ECO111_RS16655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECO111_RS16665	COG1393	Belongs to the ArsC family
ECO111_RS16680	COG0400	carboxylic ester hydrolase activity
ECO111_RS16690	COG2321	neutral zinc metallopeptidase
ECO111_RS16715	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ECO111_RS16725	COG2716	regulation of RNA biosynthetic process
ECO111_RS16730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ECO111_RS16735	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS16740	COG0651	ATP synthesis coupled electron transport
ECO111_RS16745	COG0650	Formate hydrogenlyase subunit 4
ECO111_RS16750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECO111_RS16755	COG4237	Hydrogenase 4 membrane
ECO111_RS16760	COG0651	ATP synthesis coupled electron transport
ECO111_RS16765	COG3261	NADH dehydrogenase
ECO111_RS16765	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ECO111_RS16770	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECO111_RS16785	COG3604	Transcriptional regulator
ECO111_RS16790	COG2116	formate transmembrane transporter activity
ECO111_RS16795	COG0628	permease
ECO111_RS16800	COG4783	chaperone-mediated protein folding
ECO111_RS16805	COG1393	Belongs to the ArsC family
ECO111_RS16815	COG2233	PERMEase
ECO111_RS16830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ECO111_RS16835	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ECO111_RS16840	COG0248	Ppx GppA phosphatase
ECO111_RS16845	COG2200	EAL domain
ECO111_RS16860	COG3133	Outer membrane lipoprotein
ECO111_RS16875	COG0517	IMP dehydrogenase activity
ECO111_RS16875	COG0516	GMP reductase activity
ECO111_RS16885	COG1645	bacterial-type flagellum-dependent swarming motility
ECO111_RS16900	COG2976	Protein conserved in bacteria
ECO111_RS16930	COG4953	penicillin-binding protein 1C
ECO111_RS16935	COG2373	Large extracellular alpha-helical protein
ECO111_RS16940	COG2897	thiosulfate sulfurtransferase activity
ECO111_RS16955	COG2975	iron-sulfur cluster assembly
ECO111_RS16960	COG0633	Ferredoxin
ECO111_RS16980	COG0822	iron-sulfur transferase activity
ECO111_RS17000	COG0483	inositol monophosphate 1-phosphatase activity
ECO111_RS17005	COG1073	alpha beta
ECO111_RS17010	COG3711	transcriptional antiterminator
ECO111_RS17015	COG2814	Major facilitator Superfamily
ECO111_RS17020	COG0583	DNA-binding transcription factor activity
ECO111_RS17025	COG4638	Rieske (2fe-2S)
ECO111_RS17050	COG2259	Doxx family
ECO111_RS17055	COG2017	converts alpha-aldose to the beta-anomer
ECO111_RS17060	COG1063	alcohol dehydrogenase
ECO111_RS17065	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECO111_RS17070	COG1129	ABC transporter
ECO111_RS17075	COG1879	ABC-type sugar transport system periplasmic component
ECO111_RS17080	COG1879	ABC-type sugar transport system periplasmic component
ECO111_RS17090	COG1940	carbohydrate kinase activity
ECO111_RS17100	COG1017	nitric oxide dioxygenase activity
ECO111_RS17100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECO111_RS17105	COG0347	Belongs to the P(II) protein family
ECO111_RS17110	COG2204	response regulator
ECO111_RS17115	COG3170	Tfp pilus assembly protein FimV
ECO111_RS17120	COG2205	protein histidine kinase activity
ECO111_RS17125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ECO111_RS17125	COG0047	phosphoribosylformylglycinamidine synthase activity
ECO111_RS17140	COG0560	Phosphoserine phosphatase
ECO111_RS17145	COG1737	Transcriptional regulator
ECO111_RS17150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS17175	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ECO111_RS17195	COG0681	Belongs to the peptidase S26 family
ECO111_RS17205	COG3086	response to oxidative stress
ECO111_RS17210	COG3026	antisigma factor binding
ECO111_RS17215	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ECO111_RS17220	COG1595	DNA-templated transcription, initiation
ECO111_RS17230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ECO111_RS17240	COG0513	Belongs to the DEAD box helicase family
ECO111_RS17250	COG0583	DNA-binding transcription factor activity
ECO111_RS17270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECO111_RS17280	COG3118	belongs to the thioredoxin family
ECO111_RS17285	COG3148	PFAM DTW domain containing protein
ECO111_RS17290	COG1042	CoA-binding domain protein
ECO111_RS17290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECO111_RS17290	COG0045	succinate-CoA ligase (ADP-forming) activity
ECO111_RS17295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECO111_RS17300	COG5544	Lipoprotein
ECO111_RS17305	COG0477	Major facilitator Superfamily
ECO111_RS17330	COG0542	response to heat
ECO111_RS17335	COG1496	oxidoreductase activity
ECO111_RS17340	COG0564	pseudouridine synthase activity
ECO111_RS17345	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECO111_RS17355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECO111_RS17360	COG1605	Chorismate mutase
ECO111_RS17360	COG0077	Prephenate dehydratase
ECO111_RS17365	COG0287	Prephenate dehydrogenase
ECO111_RS17365	COG1605	Chorismate mutase
ECO111_RS17370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECO111_RS17385	COG2199	diguanylate cyclase activity
ECO111_RS17390	COG2885	chlorophyll binding
ECO111_RS17415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ECO111_RS17420	COG4137	Cytochrome C assembly protein
ECO111_RS17425	COG4536	flavin adenine dinucleotide binding
ECO111_RS17445	COG0497	DNA recombination
ECO111_RS17450	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECO111_RS17460	COG2867	negative regulation of translational initiation
ECO111_RS17480	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECO111_RS17620	COG0740	serine-type endopeptidase activity
ECO111_RS17655	COG0582	viral genome integration into host DNA
ECO111_RS17675	COG0366	Alpha amylase catalytic
ECO111_RS17680	COG0366	Alpha amylase catalytic
ECO111_RS17690	COG0579	oxidoreductase
ECO111_RS17695	COG1012	belongs to the aldehyde dehydrogenase family
ECO111_RS17700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECO111_RS17705	COG1113	amino acid transport
ECO111_RS17710	COG1802	Transcriptional regulator
ECO111_RS17715	COG1652	LysM domain
ECO111_RS17720	COG0401	homolog of Blt101
ECO111_RS17725	COG0640	Transcriptional regulator
ECO111_RS17730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECO111_RS17735	COG2916	Histone family protein nucleoid-structuring protein H-NS
ECO111_RS17750	COG4575	ribosome binding
ECO111_RS17755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECO111_RS17765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECO111_RS17770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECO111_RS17775	COG4175	Glycine betaine
ECO111_RS17780	COG4176	ABC-type proline glycine betaine transport system permease component
ECO111_RS17785	COG2113	Glycine betaine
ECO111_RS17790	COG2814	Major facilitator Superfamily
ECO111_RS17795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ECO111_RS17805	COG1846	Transcriptional regulator
ECO111_RS17810	COG1566	PFAM secretion protein HlyD family protein
ECO111_RS17815	COG2814	Major facilitator Superfamily
ECO111_RS17830	COG1238	metal cluster binding
ECO111_RS17835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECO111_RS17865	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ECO111_RS17890	COG1546	Belongs to the CinA family
ECO111_RS17895	COG2951	lytic endotransglycosylase activity
ECO111_RS17900	COG3730	PTS system glucitol sorbitol-specific
ECO111_RS17905	COG3732	PTS system glucitol sorbitol-specific
ECO111_RS17915	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS17920	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS17925	COG1349	DNA-binding transcription factor activity
ECO111_RS17950	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ECO111_RS17955	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS17960	COG1609	Transcriptional regulator
ECO111_RS17965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS17965	COG1263	PTS System
ECO111_RS17970	COG2723	6-phospho-beta-galactosidase activity
ECO111_RS17975	COG5499	transcription regulator containing HTH domain
ECO111_RS17980	COG4680	protein conserved in bacteria
ECO111_RS17990	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECO111_RS18000	COG3260	NADH ubiquinone oxidoreductase 20
ECO111_RS18005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECO111_RS18010	COG3261	NADH dehydrogenase
ECO111_RS18010	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ECO111_RS18015	COG0650	Formate hydrogenlyase subunit 4
ECO111_RS18020	COG0651	ATP synthesis coupled electron transport
ECO111_RS18025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS18040	COG0375	protein maturation
ECO111_RS18045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ECO111_RS18050	COG0298	carbon dioxide binding
ECO111_RS18055	COG0409	Hydrogenase expression formation protein
ECO111_RS18060	COG0309	Hydrogenase expression formation protein (HypE)
ECO111_RS18065	COG3604	Transcriptional regulator
ECO111_RS18080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECO111_RS18085	COG1349	DNA-binding transcription factor activity
ECO111_RS18090	COG2084	Dehydrogenase
ECO111_RS18095	COG3395	kinase activity
ECO111_RS18100	COG0235	Class ii aldolase
ECO111_RS18105	COG3622	Belongs to the hyi family
ECO111_RS18110	COG2610	gluconate transmembrane transporter activity
ECO111_RS18120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ECO111_RS18135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECO111_RS18140	COG4942	peptidase
ECO111_RS18140	COG1388	LysM domain
ECO111_RS18195	COG2234	aminopeptidase activity
ECO111_RS18200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECO111_RS18205	COG1518	maintenance of DNA repeat elements
ECO111_RS18220	COG1857	crispr-associated protein
ECO111_RS18235	COG1203	CRISPR-associated helicase, Cas3
ECO111_RS18260	COG0720	synthase
ECO111_RS18265	COG0644	oxidoreductase
ECO111_RS18270	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECO111_RS18275	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ECO111_RS18280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ECO111_RS18285	COG2086	electron transfer activity
ECO111_RS18290	COG0477	Major facilitator Superfamily
ECO111_RS18295	COG0277	FAD linked oxidase domain protein
ECO111_RS18300	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS18305	COG2223	nitrite transmembrane transporter activity
ECO111_RS18310	COG1070	Carbohydrate kinase
ECO111_RS18315	COG0602	queuosine metabolic process
ECO111_RS18325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ECO111_RS18340	COG3956	TIGRFAM MazG family protein
ECO111_RS18345	COG2337	Toxic component of a toxin-antitoxin (TA) module
ECO111_RS18350	COG2336	PFAM SpoVT AbrB
ECO111_RS18355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECO111_RS18365	COG3437	response regulator, receiver
ECO111_RS18365	COG3850	Histidine kinase
ECO111_RS18365	COG4999	Histidine kinase
ECO111_RS18365	COG2205	protein histidine kinase activity
ECO111_RS18370	COG4948	Mandelate Racemase Muconate Lactonizing
ECO111_RS18375	COG4948	Mandelate Racemase Muconate Lactonizing
ECO111_RS18380	COG2271	Major facilitator Superfamily
ECO111_RS18385	COG0716	FMN binding
ECO111_RS18390	COG0564	pseudouridine synthase activity
ECO111_RS18395	COG3098	single-species biofilm formation
ECO111_RS18415	COG1611	Belongs to the LOG family
ECO111_RS18420	COG0814	amino acid
ECO111_RS18425	COG1760	l-serine dehydratase
ECO111_RS18435	COG1454	alcohol dehydrogenase
ECO111_RS18440	COG0235	Class ii aldolase
ECO111_RS18445	COG0738	Major facilitator superfamily
ECO111_RS18455	COG1070	Carbohydrate kinase
ECO111_RS18465	COG1349	DNA-binding transcription factor activity
ECO111_RS18475	COG2363	Small membrane protein
ECO111_RS18480	COG0583	DNA-binding transcription factor activity
ECO111_RS18490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ECO111_RS18495	COG2166	iron-sulfur cluster assembly
ECO111_RS18500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ECO111_RS18505	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ECO111_RS18535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECO111_RS18545	COG3711	transcriptional antiterminator
ECO111_RS18550	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECO111_RS18555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ECO111_RS18555	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ECO111_RS18560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ECO111_RS18565	COG1074	ATP-dependent DNA helicase activity
ECO111_RS18570	COG1025	Belongs to the peptidase M16 family
ECO111_RS18575	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ECO111_RS18580	COG4967	type IV pilus modification protein PilV
ECO111_RS18590	COG4795	General secretion pathway protein
ECO111_RS18595	COG2165	general secretion pathway protein
ECO111_RS18610	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ECO111_RS18635	COG0861	Integral membrane protein TerC family
ECO111_RS18645	COG0667	Aldo Keto reductase
ECO111_RS18660	COG1609	Transcriptional regulator
ECO111_RS18670	COG0583	DNA-binding transcription factor activity
ECO111_RS18675	COG1794	racemase activity, acting on amino acids and derivatives
ECO111_RS18680	COG2814	Major facilitator Superfamily
ECO111_RS18685	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS18695	COG0183	Belongs to the thiolase family
ECO111_RS18700	COG0814	amino acid
ECO111_RS18705	COG2771	luxR family
ECO111_RS18710	COG3710	Transcriptional regulator
ECO111_RS18735	COG0457	Tetratricopeptide repeat
ECO111_RS18735	COG3710	Transcriptional regulator
ECO111_RS18750	COG2197	response regulator
ECO111_RS18755	COG2197	response regulator
ECO111_RS18850	COG4942	peptidase
ECO111_RS18855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECO111_RS18860	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECO111_RS18865	COG2080	2 iron, 2 sulfur cluster binding
ECO111_RS18870	COG3829	transcription factor binding
ECO111_RS18875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECO111_RS18880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECO111_RS18885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECO111_RS18895	COG0549	Belongs to the carbamate kinase family
ECO111_RS18900	COG3608	succinylglutamate desuccinylase aspartoacylase
ECO111_RS18900	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ECO111_RS18905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECO111_RS18910	COG2068	MobA-Related Protein
ECO111_RS18915	COG0493	'glutamate synthase
ECO111_RS18915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS18920	COG0402	S-adenosylhomocysteine deaminase activity
ECO111_RS18925	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECO111_RS18930	COG2080	2 iron, 2 sulfur cluster binding
ECO111_RS18930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECO111_RS18935	COG2233	PERMEase
ECO111_RS18940	COG0402	S-adenosylhomocysteine deaminase activity
ECO111_RS18945	COG2252	PERMEase
ECO111_RS18950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS18955	COG0493	'glutamate synthase
ECO111_RS18955	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS18965	COG2233	PERMEase
ECO111_RS18990	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ECO111_RS18995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECO111_RS19000	COG4974	Belongs to the 'phage' integrase family
ECO111_RS19005	COG0716	FMN binding
ECO111_RS19015	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ECO111_RS19025	COG1272	protein, Hemolysin III
ECO111_RS19035	COG2723	6-phospho-beta-galactosidase activity
ECO111_RS19040	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS19060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECO111_RS19065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECO111_RS19070	COG0006	proline dipeptidase activity
ECO111_RS19085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ECO111_RS19095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECO111_RS19115	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ECO111_RS19115	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ECO111_RS19120	COG1703	isobutyryl-CoA mutase activity
ECO111_RS19125	COG1024	Enoyl-CoA hydratase
ECO111_RS19130	COG0427	acetyl-CoA hydrolase
ECO111_RS19135	COG0583	DNA-binding transcription factor activity
ECO111_RS19140	COG2968	Membrane
ECO111_RS19150	COG0668	transmembrane transport
ECO111_RS19155	COG0191	fructose-bisphosphate aldolase activity
ECO111_RS19185	COG1122	ATPase activity
ECO111_RS19190	COG1122	ATPase activity
ECO111_RS19195	COG1072	(Pantothenic acid kinase))
ECO111_RS19205	COG1494	fructose-1,6-bisphosphatase
ECO111_RS19210	COG1063	alcohol dehydrogenase
ECO111_RS19215	COG2213	PTS system mannitol-specific
ECO111_RS19220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS19225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECO111_RS19230	COG0501	Belongs to the peptidase M48B family
ECO111_RS19245	COG3716	PTS system mannose fructose sorbose family IID component
ECO111_RS19250	COG3715	PTS system
ECO111_RS19255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS19255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS19280	COG1166	arginine decarboxylase activity
ECO111_RS19305	COG2814	Major facilitator Superfamily
ECO111_RS19315	COG2356	endonuclease I
ECO111_RS19320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ECO111_RS19325	COG0189	ligase activity
ECO111_RS19340	COG2805	Type II/IV secretion system protein
ECO111_RS19345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ECO111_RS19350	COG0762	integral membrane protein
ECO111_RS19365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECO111_RS19370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECO111_RS19375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECO111_RS19390	COG0252	asparaginase activity
ECO111_RS19405	COG3171	Protein conserved in bacteria
ECO111_RS19415	COG1194	a g-specific adenine glycosylase
ECO111_RS19430	COG2211	Major facilitator Superfamily
ECO111_RS19435	COG1982	Orn Lys Arg decarboxylase major
ECO111_RS19440	COG1811	Na channel or pump
ECO111_RS19450	COG0582	viral genome integration into host DNA
ECO111_RS19455	COG4372	Transposase
ECO111_RS19515	COG2801	Transposase and inactivated derivatives
ECO111_RS19770	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECO111_RS19800	COG2165	general secretion pathway protein
ECO111_RS19805	COG1459	type II secretion system
ECO111_RS19810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECO111_RS19835	COG3064	Membrane
ECO111_RS19845	COG1620	l-lactate permease
ECO111_RS19850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECO111_RS19855	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ECO111_RS19860	COG0247	lactate metabolic process
ECO111_RS19865	COG0277	FAD linked oxidase domain protein
ECO111_RS19870	COG0277	FAD linked oxidase domain protein
ECO111_RS19875	COG2186	Transcriptional regulator
ECO111_RS19880	COG0456	acetyltransferase
ECO111_RS19885	COG0318	PFAM AMP-dependent synthetase and ligase
ECO111_RS19895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECO111_RS19900	COG0156	8-amino-7-oxononanoate synthase activity
ECO111_RS19910	COG0795	lipopolysaccharide-transporting ATPase activity
ECO111_RS19915	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ECO111_RS19925	COG2244	polysaccharide biosynthetic process
ECO111_RS19930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECO111_RS19935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECO111_RS19940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECO111_RS19945	COG0306	phosphate transporter
ECO111_RS19950	COG0306	phosphate transporter
ECO111_RS19955	COG0754	glutathionylspermidine amidase activity
ECO111_RS19960	COG0625	glutathione transferase activity
ECO111_RS19965	COG0298	carbon dioxide binding
ECO111_RS19975	COG1773	rubredoxin
ECO111_RS19980	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECO111_RS19985	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ECO111_RS19990	COG5557	Pfam Polysulphide reductase, NrfD
ECO111_RS19995	COG0437	4 iron, 4 sulfur cluster binding
ECO111_RS20000	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ECO111_RS20020	COG0667	Aldo Keto reductase
ECO111_RS20030	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS20035	COG0848	biopolymer transport protein
ECO111_RS20040	COG0811	peptide transport
ECO111_RS20050	COG0626	cystathionine gamma-synthase activity
ECO111_RS20055	COG0586	Pfam SNARE associated Golgi protein
ECO111_RS20060	COG2207	Transcriptional regulator
ECO111_RS20070	COG1979	alcohol dehydrogenase
ECO111_RS20075	COG0656	L-ascorbic acid biosynthetic process
ECO111_RS20085	COG4238	major outer membrane lipoprotein
ECO111_RS20090	COG1032	radical SAM domain protein
ECO111_RS20095	COG2132	Multicopper oxidase
ECO111_RS20100	COG0204	Acyl-transferase
ECO111_RS20105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECO111_RS20115	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ECO111_RS20120	COG3111	PFAM Bacterial OB fold (BOF) protein
ECO111_RS20125	COG0745	RESPONSE REGULATOR receiver
ECO111_RS20130	COG0642	Histidine kinase
ECO111_RS20140	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECO111_RS20145	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ECO111_RS20150	COG0187	DNA topoisomerase II activity
ECO111_RS20155	COG3150	esterase
ECO111_RS20160	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ECO111_RS20165	COG3151	Protein conserved in bacteria
ECO111_RS20170	COG0494	nUDIX hydrolase
ECO111_RS20175	COG1538	Outer membrane efflux protein
ECO111_RS20190	COG0754	glutathionylspermidine amidase activity
ECO111_RS20195	COG3384	dioxygenase
ECO111_RS20215	COG2960	long-chain fatty acid transporting porin activity
ECO111_RS20220	COG3539	Fimbrial protein
ECO111_RS20225	COG3188	usher protein
ECO111_RS20235	COG3539	Fimbrial protein
ECO111_RS20245	COG1585	Membrane protein implicated in regulation of membrane protease activity
ECO111_RS20250	COG2268	Band 7 protein
ECO111_RS20275	COG3025	triphosphatase activity
ECO111_RS20285	COG4991	sh3 domain protein
ECO111_RS20300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECO111_RS20310	COG0583	DNA-binding transcription factor activity
ECO111_RS20315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECO111_RS20320	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECO111_RS20325	COG0471	metal ion transport
ECO111_RS20335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ECO111_RS20340	COG0358	DNA primase activity
ECO111_RS20345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECO111_RS20360	COG2375	cellular response to nickel ion
ECO111_RS20365	COG1695	Transcriptional regulator
ECO111_RS20370	COG0840	transmembrane signaling receptor activity
ECO111_RS20380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECO111_RS20385	COG1609	Transcriptional regulator
ECO111_RS20390	COG3250	beta-galactosidase activity
ECO111_RS20395	COG2731	YhcH YjgK YiaL family protein
ECO111_RS20400	COG0531	amino acid
ECO111_RS20410	COG3408	Glycogen debranching enzyme
ECO111_RS20410	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ECO111_RS20415	COG1902	pentaerythritol trinitrate reductase activity
ECO111_RS20415	COG0446	pyridine nucleotide-disulphide oxidoreductase
ECO111_RS20420	COG5499	transcription regulator containing HTH domain
ECO111_RS20425	COG4680	protein conserved in bacteria
ECO111_RS20435	COG1451	nucleotide metabolic process
ECO111_RS20440	COG2949	membrane
ECO111_RS20445	COG0673	inositol 2-dehydrogenase activity
ECO111_RS20450	COG0861	Integral membrane protein TerC family
ECO111_RS20455	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ECO111_RS20465	COG2721	sulfolactate sulfo-lyase activity
ECO111_RS20475	COG2271	Major facilitator Superfamily
ECO111_RS20500	COG2186	Transcriptional regulator
ECO111_RS20505	COG0586	Pfam SNARE associated Golgi protein
ECO111_RS20515	COG1422	Protein of unknown function (DUF1090)
ECO111_RS20520	COG4575	ribosome binding
ECO111_RS20525	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ECO111_RS20535	COG2259	Doxx family
ECO111_RS20540	COG0435	Glutathione S-transferase
ECO111_RS20545	COG3152	Membrane
ECO111_RS20550	COG3152	Membrane
ECO111_RS20555	COG0583	DNA-binding transcription factor activity
ECO111_RS20560	COG1741	Belongs to the pirin family
ECO111_RS20575	COG0814	amino acid
ECO111_RS20580	COG1760	l-serine dehydratase
ECO111_RS20585	COG0251	oxidation-reduction process
ECO111_RS20590	COG1882	Formate acetyltransferase
ECO111_RS20595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECO111_RS20605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECO111_RS20610	COG0583	DNA-binding transcription factor activity
ECO111_RS20630	COG1929	Belongs to the glycerate kinase type-1 family
ECO111_RS20635	COG2084	Dehydrogenase
ECO111_RS20645	COG2271	Major facilitator Superfamily
ECO111_RS20655	COG2721	sulfolactate sulfo-lyase activity
ECO111_RS20660	COG2002	toxin-antitoxin pair type II binding
ECO111_RS20670	COG1349	DNA-binding transcription factor activity
ECO111_RS20680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS20690	COG3716	PTS system mannose fructose sorbose family IID component
ECO111_RS20695	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS20700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECO111_RS20705	COG2222	sugar isomerase
ECO111_RS20715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS20720	COG3715	PTS system
ECO111_RS20725	COG3716	PTS system mannose fructose sorbose family IID component
ECO111_RS20730	COG0363	glucosamine-6-phosphate deaminase activity
ECO111_RS20735	COG3539	Fimbrial protein
ECO111_RS20740	COG3121	Chaperone
ECO111_RS20745	COG3188	usher protein
ECO111_RS20750	COG3539	Fimbrial protein
ECO111_RS20755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ECO111_RS20775	COG2823	Periplasmic or secreted lipoprotein
ECO111_RS20780	COG0701	Predicted permease
ECO111_RS20785	COG0702	epimerase
ECO111_RS20790	COG0693	protein deglycase activity
ECO111_RS20805	COG3153	acetyltransferase
ECO111_RS20810	COG3154	lipid carrier protein
ECO111_RS20815	COG0826	peptidase U32
ECO111_RS20820	COG0826	peptidase U32
ECO111_RS20825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECO111_RS20830	COG0814	amino acid
ECO111_RS20840	COG0513	Belongs to the DEAD box helicase family
ECO111_RS20875	COG0195	Participates in both transcription termination and antitermination
ECO111_RS20895	COG2194	sulfuric ester hydrolase activity
ECO111_RS20910	COG2194	sulfuric ester hydrolase activity
ECO111_RS20920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECO111_RS20930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ECO111_RS20935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ECO111_RS20945	COG1534	Rna-binding protein
ECO111_RS20950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECO111_RS20955	COG2027	D-alanyl-D-alanine carboxypeptidase
ECO111_RS20965	COG0697	spore germination
ECO111_RS20980	COG0142	geranyltranstransferase activity
ECO111_RS20985	COG3423	Transcriptional regulator
ECO111_RS20995	COG5007	Belongs to the BolA IbaG family
ECO111_RS21000	COG3113	response to antibiotic
ECO111_RS21005	COG2854	intermembrane phospholipid transfer
ECO111_RS21010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECO111_RS21015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ECO111_RS21020	COG1127	ABC transporter
ECO111_RS21025	COG0530	calcium, potassium:sodium antiporter activity
ECO111_RS21030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECO111_RS21030	COG0517	IMP dehydrogenase activity
ECO111_RS21035	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ECO111_RS21040	COG3117	lipopolysaccharide transmembrane transporter activity
ECO111_RS21045	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ECO111_RS21050	COG1137	ATPase activity
ECO111_RS21055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ECO111_RS21060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECO111_RS21075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS21080	COG0515	serine threonine protein kinase
ECO111_RS21090	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ECO111_RS21095	COG2198	Histidine kinase
ECO111_RS21095	COG5002	protein histidine kinase activity
ECO111_RS21095	COG0784	Response regulator, receiver
ECO111_RS21100	COG1242	4 iron, 4 sulfur cluster binding
ECO111_RS21105	COG0070	glutamate synthase
ECO111_RS21105	COG0069	glutamate synthase activity
ECO111_RS21105	COG0067	glutamate synthase
ECO111_RS21110	COG0493	'glutamate synthase
ECO111_RS21120	COG2731	YhcH YjgK YiaL family protein
ECO111_RS21150	COG3069	C4-dicarboxylate transmembrane transporter activity
ECO111_RS21155	COG2969	positive regulation of protein catabolic process
ECO111_RS21160	COG0625	glutathione transferase activity
ECO111_RS21175	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ECO111_RS21180	COG3105	Protein conserved in bacteria
ECO111_RS21185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECO111_RS21190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECO111_RS21210	COG2732	(Barnase) inhibitor
ECO111_RS21230	COG0583	DNA-binding transcription factor activity
ECO111_RS21235	COG0312	modulator of DNA gyrase
ECO111_RS21240	COG3164	Protein of unknown function
ECO111_RS21245	COG1530	ribonuclease E activity
ECO111_RS21255	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ECO111_RS21260	COG1792	Involved in formation and maintenance of cell shape
ECO111_RS21265	COG1077	Cell shape determining protein MreB Mrl
ECO111_RS21275	COG2200	EAL domain
ECO111_RS21275	COG2199	diguanylate cyclase activity
ECO111_RS21280	COG0604	alcohol dehydrogenase
ECO111_RS21300	COG0511	ligase activity, forming carbon-carbon bonds
ECO111_RS21305	COG0439	Biotin carboxylase
ECO111_RS21315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECO111_RS21320	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECO111_RS21325	COG1129	ABC transporter
ECO111_RS21330	COG1879	ABC-type sugar transport system periplasmic component
ECO111_RS21340	COG1349	DNA-binding transcription factor activity
ECO111_RS21345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECO111_RS21350	COG3924	membrane
ECO111_RS21355	COG4145	pantothenate transmembrane transporter activity
ECO111_RS21365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECO111_RS21375	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ECO111_RS21385	COG1309	transcriptional regulator
ECO111_RS21390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECO111_RS21395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECO111_RS21415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECO111_RS21420	COG4597	amino acid ABC transporter
ECO111_RS21425	COG0765	amino acid transport
ECO111_RS21430	COG1126	abc transporter atp-binding protein
ECO111_RS21470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECO111_RS21490	COG0551	DNA topoisomerase type I activity
ECO111_RS21520	COG0569	domain protein
ECO111_RS21530	COG3036	rescue of stalled ribosome
ECO111_RS21535	COG0789	Transcriptional regulator
ECO111_RS21575	COG0201	protein transport
ECO111_RS21665	COG0089	rRNA binding
ECO111_RS21740	COG2964	Protein conserved in bacteria
ECO111_RS21745	COG0545	Peptidyl-prolyl cis-trans isomerase
ECO111_RS21755	COG1047	Peptidyl-prolyl cis-trans
ECO111_RS21760	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ECO111_RS21775	COG0488	(ABC) transporter
ECO111_RS21780	COG0429	hydrolase of the alpha beta-hydrolase fold
ECO111_RS21790	COG3954	Phosphoribulokinase
ECO111_RS21795	COG1765	OsmC-like protein
ECO111_RS21805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECO111_RS21810	COG1289	transmembrane transporter activity
ECO111_RS21815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ECO111_RS21820	COG0512	Glutamine amidotransferase of anthranilate synthase
ECO111_RS21825	COG2184	nucleotidyltransferase activity
ECO111_RS21835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECO111_RS21845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ECO111_RS21850	COG2146	nitrite reductase [NAD(P)H] activity
ECO111_RS21855	COG2116	formate transmembrane transporter activity
ECO111_RS21870	COG0531	amino acid
ECO111_RS21875	COG2222	sugar isomerase
ECO111_RS21880	COG1082	Xylose isomerase domain protein TIM barrel
ECO111_RS21890	COG2188	Transcriptional regulator
ECO111_RS21895	COG0626	cystathionine gamma-synthase activity
ECO111_RS21910	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ECO111_RS21915	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ECO111_RS21920	COG3457	Alanine racemase
ECO111_RS21930	COG2188	Transcriptional regulator
ECO111_RS21935	COG0180	Tryptophanyl-tRNA synthetase
ECO111_RS21940	COG0546	phosphoglycolate phosphatase activity
ECO111_RS21945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECO111_RS21950	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ECO111_RS21955	COG3266	domain, Protein
ECO111_RS21970	COG4796	Type ii and iii secretion system protein
ECO111_RS21985	COG3166	PFAM Fimbrial assembly family protein
ECO111_RS21990	COG4972	Pilus assembly protein
ECO111_RS21995	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ECO111_RS22000	COG0494	nUDIX hydrolase
ECO111_RS22010	COG1011	Hydrolase
ECO111_RS22015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ECO111_RS22025	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ECO111_RS22050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECO111_RS22055	COG2183	response to ionizing radiation
ECO111_RS22060	COG1918	ferrous iron import across plasma membrane
ECO111_RS22065	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ECO111_RS22075	COG5464	transposase or invertase
ECO111_RS22095	COG2610	gluconate transmembrane transporter activity
ECO111_RS22100	COG1640	4-alpha-glucanotransferase
ECO111_RS22105	COG0058	SHG alpha-glucan phosphorylase activity
ECO111_RS22120	COG1690	Belongs to the RtcB family
ECO111_RS22125	COG4650	regulator
ECO111_RS22130	COG1349	DNA-binding transcription factor activity
ECO111_RS22145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECO111_RS22165	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECO111_RS22170	COG0058	SHG alpha-glucan phosphorylase activity
ECO111_RS22195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECO111_RS22200	COG2095	MarC family integral membrane protein
ECO111_RS22205	COG2610	gluconate transmembrane transporter activity
ECO111_RS22210	COG3265	gluconokinase activity
ECO111_RS22215	COG1609	Transcriptional regulator
ECO111_RS22220	COG1741	Belongs to the pirin family
ECO111_RS22225	COG0673	inositol 2-dehydrogenase activity
ECO111_RS22230	COG1247	-acetyltransferase
ECO111_RS22235	COG3157	Type VI secretion system effector, Hcp
ECO111_RS22250	COG0405	Gamma-glutamyltransferase
ECO111_RS22260	COG0584	glycerophosphoryl diester phosphodiesterase
ECO111_RS22265	COG3842	ATPase activity
ECO111_RS22275	COG1175	transmembrane transport
ECO111_RS22280	COG1653	transport
ECO111_RS22290	COG0410	ABC transporter
ECO111_RS22295	COG0411	ABC transporter
ECO111_RS22300	COG4177	L-phenylalanine transmembrane transporter activity
ECO111_RS22305	COG0559	Belongs to the binding-protein-dependent transport system permease family
ECO111_RS22310	COG0683	leucine binding
ECO111_RS22315	COG0456	acetyltransferase
ECO111_RS22325	COG0683	leucine binding
ECO111_RS22330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECO111_RS22335	COG2177	Part of the ABC transporter FtsEX involved in
ECO111_RS22340	COG2884	Cell division ATP-binding protein ftsE
ECO111_RS22345	COG0552	protein localization to endoplasmic reticulum
ECO111_RS22350	COG0742	ribosomal rna small subunit methyltransferase
ECO111_RS22355	COG3776	membrane
ECO111_RS22365	COG3714	YhhN family
ECO111_RS22380	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ECO111_RS22395	COG0628	permease
ECO111_RS22400	COG2091	lysine biosynthetic process via aminoadipic acid
ECO111_RS22405	COG0747	negative chemotaxis
ECO111_RS22410	COG0601	transmembrane transport
ECO111_RS22415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECO111_RS22420	COG0444	Belongs to the ABC transporter superfamily
ECO111_RS22435	COG3209	COG3209 Rhs family protein
ECO111_RS22450	COG5433	transposase activity
ECO111_RS22460	COG0842	Transport permease protein
ECO111_RS22465	COG1129	ABC transporter
ECO111_RS22465	COG0842	Transport permease protein
ECO111_RS22470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECO111_RS22500	COG2081	HI0933 family
ECO111_RS22505	COG0306	phosphate transporter
ECO111_RS22515	COG0589	response to stress
ECO111_RS22520	COG3104	oligopeptide transport
ECO111_RS22530	COG0339	signal peptide processing
ECO111_RS22535	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ECO111_RS22540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECO111_RS22555	COG0640	Transcriptional regulator
ECO111_RS22560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECO111_RS22565	COG1393	Belongs to the ArsC family
ECO111_RS22595	COG3065	identical protein binding
ECO111_RS22605	COG1285	pathogenesis
ECO111_RS22620	COG3247	response to pH
ECO111_RS22625	COG2771	luxR family
ECO111_RS22635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECO111_RS22640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECO111_RS22645	COG2207	Transcriptional regulator
ECO111_RS22655	COG0076	glutamate decarboxylase activity
ECO111_RS22660	COG1858	cytochrome C peroxidase
ECO111_RS22670	COG2197	response regulator
ECO111_RS22675	COG0583	DNA-binding transcription factor activity
ECO111_RS22680	COG1295	ribonuclease BN
ECO111_RS22685	COG0477	Major facilitator Superfamily
ECO111_RS22690	COG2982	Protein involved in outer membrane biogenesis
ECO111_RS22695	COG2200	EAL domain
ECO111_RS22710	COG0612	Peptidase, M16
ECO111_RS22720	COG2200	EAL domain
ECO111_RS22720	COG2199	diguanylate cyclase activity
ECO111_RS22725	COG0457	Tetratricopeptide repeat
ECO111_RS22725	COG3118	belongs to the thioredoxin family
ECO111_RS22730	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ECO111_RS22735	COG1215	transferase activity, transferring glycosyl groups
ECO111_RS22740	COG1215	transferase activity, transferring glycosyl groups
ECO111_RS22765	COG2194	sulfuric ester hydrolase activity
ECO111_RS22785	COG0814	amino acid
ECO111_RS22790	COG4608	Belongs to the ABC transporter superfamily
ECO111_RS22795	COG0444	Belongs to the ABC transporter superfamily
ECO111_RS22800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECO111_RS22805	COG0601	transmembrane transport
ECO111_RS22815	COG0747	negative chemotaxis
ECO111_RS22830	COG2194	sulfuric ester hydrolase activity
ECO111_RS22860	COG2223	nitrite transmembrane transporter activity
ECO111_RS22865	COG5571	outer membrane autotransporter
ECO111_RS22870	COG2818	Glycosylase
ECO111_RS22875	COG0456	acetyltransferase
ECO111_RS22880	COG0243	molybdopterin cofactor binding
ECO111_RS22885	COG2885	chlorophyll binding
ECO111_RS22900	COG2944	sequence-specific DNA binding
ECO111_RS22905	COG1278	Cold shock
ECO111_RS22930	COG3274	enterobacterial common antigen metabolic process
ECO111_RS22935	COG4682	membrane
ECO111_RS22940	COG4682	membrane
ECO111_RS22945	COG1070	Carbohydrate kinase
ECO111_RS22955	COG4213	ABC transporter substrate-binding protein
ECO111_RS22960	COG1129	ABC transporter
ECO111_RS22965	COG4214	carbohydrate transport
ECO111_RS22970	COG2207	Transcriptional regulator
ECO111_RS22970	COG1609	Transcriptional regulator
ECO111_RS22975	COG2992	FlgJ-related protein
ECO111_RS22980	COG0366	Alpha amylase catalytic
ECO111_RS22985	COG3977	Valine--pyruvate aminotransferase
ECO111_RS22995	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECO111_RS23000	COG1414	Transcriptional regulator
ECO111_RS23010	COG2731	YhcH YjgK YiaL family protein
ECO111_RS23015	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECO111_RS23020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECO111_RS23025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECO111_RS23030	COG1070	Carbohydrate kinase
ECO111_RS23035	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ECO111_RS23040	COG3623	hexulose-6-phosphate isomerase
ECO111_RS23045	COG0235	Class ii aldolase
ECO111_RS23050	COG3713	MltA-interacting MipA family protein
ECO111_RS23055	COG0583	DNA-binding transcription factor activity
ECO111_RS23060	COG1566	PFAM secretion protein HlyD family protein
ECO111_RS23075	COG1012	belongs to the aldehyde dehydrogenase family
ECO111_RS23080	COG1454	alcohol dehydrogenase
ECO111_RS23085	COG3276	selenocysteine insertion sequence binding
ECO111_RS23095	COG0625	glutathione transferase activity
ECO111_RS23100	COG3209	COG3209 Rhs family protein
ECO111_RS23105	COG1413	lyase activity
ECO111_RS23110	COG3209	COG3209 Rhs family protein
ECO111_RS23115	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECO111_RS23125	COG1566	PFAM secretion protein HlyD family protein
ECO111_RS23135	COG2213	PTS system mannitol-specific
ECO111_RS23135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS23145	COG3722	fumarate hydratase activity
ECO111_RS23165	COG5295	Hep Hag repeat protein
ECO111_RS23170	COG1620	l-lactate permease
ECO111_RS23175	COG2186	Transcriptional regulator
ECO111_RS23185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ECO111_RS23190	COG1045	serine acetyltransferase
ECO111_RS23205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECO111_RS23210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECO111_RS23220	COG4942	peptidase
ECO111_RS23225	COG2861	carbohydrate metabolic process
ECO111_RS23230	COG1216	Glycosyl transferase, family 2
ECO111_RS23240	COG0156	8-amino-7-oxononanoate synthase activity
ECO111_RS23255	COG0859	PFAM glycosyl transferase family 9
ECO111_RS23260	COG0859	PFAM glycosyl transferase family 9
ECO111_RS23280	COG3642	lipopolysaccharide core region biosynthetic process
ECO111_RS23290	COG0515	serine threonine protein kinase
ECO111_RS23295	COG0438	transferase activity, transferring glycosyl groups
ECO111_RS23300	COG0859	PFAM glycosyl transferase family 9
ECO111_RS23305	COG1519	Transferase
ECO111_RS23335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ECO111_RS23360	COG1561	YicC-like family, N-terminal region
ECO111_RS23365	COG3645	SOS response
ECO111_RS23370	COG2860	membrane
ECO111_RS23380	COG0194	GDP metabolic process
ECO111_RS23390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECO111_RS23395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECO111_RS23400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ECO111_RS23410	COG0786	glutamate:sodium symporter activity
ECO111_RS23415	COG2233	PERMEase
ECO111_RS23420	COG2982	Protein involved in outer membrane biogenesis
ECO111_RS23425	COG1501	Belongs to the glycosyl hydrolase 31 family
ECO111_RS23430	COG2211	Major facilitator Superfamily
ECO111_RS23445	COG2814	Major facilitator Superfamily
ECO111_RS23450	COG0697	spore germination
ECO111_RS23455	COG1464	Belongs to the NlpA lipoprotein family
ECO111_RS23480	COG2252	PERMEase
ECO111_RS23490	COG2271	Major facilitator Superfamily
ECO111_RS23495	COG2271	Major facilitator Superfamily
ECO111_RS23500	COG3851	Histidine kinase
ECO111_RS23505	COG2197	response regulator
ECO111_RS23510	COG0440	acetolactate synthase activity
ECO111_RS23515	COG0028	Belongs to the TPP enzyme family
ECO111_RS23540	COG2814	Major facilitator Superfamily
ECO111_RS23545	COG0641	radical SAM
ECO111_RS23555	COG2149	membrane
ECO111_RS23565	COG3119	arylsulfatase activity
ECO111_RS23570	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECO111_RS23575	COG2207	Transcriptional regulator
ECO111_RS23605	COG2188	Transcriptional regulator
ECO111_RS23625	COG5645	(Lipo)protein
ECO111_RS23630	COG0823	Involved in the tonB-independent uptake of proteins
ECO111_RS23640	COG2271	Major facilitator Superfamily
ECO111_RS23650	COG0800	Aldolase
ECO111_RS23655	COG3734	2-keto-3-deoxy-galactonokinase
ECO111_RS23660	COG2186	Transcriptional regulator
ECO111_RS23670	COG0561	phosphatase activity
ECO111_RS23675	COG3753	Protein conserved in bacteria
ECO111_RS23685	COG0187	DNA topoisomerase II activity
ECO111_RS23695	COG0592	DNA-directed DNA polymerase activity
ECO111_RS23740	COG0814	amino acid
ECO111_RS23755	COG2091	lysine biosynthetic process via aminoadipic acid
ECO111_RS23760	COG0431	NADPH-dependent FMN reductase
ECO111_RS23765	COG2252	PERMEase
ECO111_RS23770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECO111_RS23780	COG3196	Protein conserved in bacteria
ECO111_RS23785	COG0363	glucosamine-6-phosphate deaminase activity
ECO111_RS23790	COG2382	esterase
ECO111_RS23800	COG2723	6-phospho-beta-galactosidase activity
ECO111_RS23810	COG3711	transcriptional antiterminator
ECO111_RS23815	COG0704	Plays a role in the regulation of phosphate uptake
ECO111_RS23820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ECO111_RS23825	COG0581	inorganic phosphate transmembrane transporter activity
ECO111_RS23830	COG0573	inorganic phosphate transmembrane transporter activity
ECO111_RS23835	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECO111_RS23845	COG3188	usher protein
ECO111_RS23855	COG3539	Fimbrial protein
ECO111_RS23860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ECO111_RS23920	COG3312	ion transport
ECO111_RS23935	COG0716	FMN binding
ECO111_RS23940	COG1522	sequence-specific DNA binding
ECO111_RS23970	COG1129	ABC transporter
ECO111_RS23975	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECO111_RS23980	COG1879	ABC-type sugar transport system periplasmic component
ECO111_RS23985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECO111_RS23990	COG1609	Transcriptional regulator
ECO111_RS23995	COG0477	Major facilitator Superfamily
ECO111_RS24000	COG2186	Transcriptional regulator
ECO111_RS24040	COG3085	chromosome segregation
ECO111_RS24045	COG0606	chelatase, subunit chli
ECO111_RS24060	COG3978	acetolactate synthase activity
ECO111_RS24065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECO111_RS24075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECO111_RS24080	COG0583	DNA-binding transcription factor activity
ECO111_RS24090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECO111_RS24095	COG3692	DNA binding
ECO111_RS24100	COG0210	DNA helicase
ECO111_RS24115	COG3118	belongs to the thioredoxin family
ECO111_RS24125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ECO111_RS24135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ECO111_RS24140	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECO111_RS24145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ECO111_RS24150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ECO111_RS24155	COG1088	dTDP-glucose 4,6-dehydratase activity
ECO111_RS24160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ECO111_RS24165	COG0456	acetyltransferase
ECO111_RS24170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ECO111_RS24175	COG2244	polysaccharide biosynthetic process
ECO111_RS24195	COG1113	amino acid transport
ECO111_RS24220	COG0641	radical SAM
ECO111_RS24225	COG3119	arylsulfatase activity
ECO111_RS24230	COG3071	HemY protein
ECO111_RS24235	COG2959	enzyme of heme biosynthesis
ECO111_RS24240	COG1587	Uroporphyrinogen-III synthase
ECO111_RS24250	COG3072	Adenylate cyclase
ECO111_RS24275	COG5567	small periplasmic lipoprotein
ECO111_RS24285	COG3159	Protein conserved in bacteria
ECO111_RS24295	COG1011	Hydrolase
ECO111_RS24300	COG0210	DNA helicase
ECO111_RS24305	COG3698	Phosphodiester glycosidase
ECO111_RS24315	COG0598	Magnesium transport protein CorA
ECO111_RS24345	COG2050	protein possibly involved in aromatic compounds catabolism
ECO111_RS24350	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ECO111_RS24355	COG0514	ATP-dependent DNA helicase (RecQ)
ECO111_RS24360	COG1280	lysine exporter protein (LysE YggA)
ECO111_RS24365	COG1280	lysine exporter protein (LysE YggA)
ECO111_RS24370	COG2267	carboxylic ester hydrolase activity
ECO111_RS24375	COG0561	phosphatase activity
ECO111_RS24380	COG0697	spore germination
ECO111_RS24385	COG0583	DNA-binding transcription factor activity
ECO111_RS24395	COG0412	Dienelactone hydrolase
ECO111_RS24400	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ECO111_RS24405	COG1322	Protein conserved in bacteria
ECO111_RS24415	COG3165	ubiquinone biosynthetic process from chorismate
ECO111_RS24425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECO111_RS24430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECO111_RS24435	COG0805	protein transport
ECO111_RS24445	COG0250	Participates in transcription elongation, termination and antitermination
ECO111_RS24450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ECO111_RS24455	COG0543	2 iron, 2 sulfur cluster binding
ECO111_RS24475	COG1739	Uncharacterized protein family UPF0029
ECO111_RS24480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECO111_RS24485	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ECO111_RS24515	COG1763	Mo-molybdopterin cofactor biosynthetic process
ECO111_RS24520	COG0746	molybdenum cofactor guanylyltransferase activity
ECO111_RS24525	COG3084	Protein conserved in bacteria
ECO111_RS24530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ECO111_RS24535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECO111_RS24540	COG5339	Protein conserved in bacteria
ECO111_RS24545	COG0204	Acyl-transferase
ECO111_RS24555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECO111_RS24555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECO111_RS24570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECO111_RS24580	COG2204	response regulator
ECO111_RS24585	COG3852	Histidine kinase
ECO111_RS24595	COG0174	glutamine synthetase
ECO111_RS24605	COG1217	gtp-binding protein TYPA
ECO111_RS24610	COG2188	Transcriptional regulator
ECO111_RS24615	COG1082	Xylose isomerase domain protein TIM barrel
ECO111_RS24620	COG2271	Major facilitator Superfamily
ECO111_RS24625	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECO111_RS24630	COG2211	Major facilitator Superfamily
ECO111_RS24635	COG2211	Major facilitator Superfamily
ECO111_RS24640	COG1501	Belongs to the glycosyl hydrolase 31 family
ECO111_RS24645	COG2017	converts alpha-aldose to the beta-anomer
ECO111_RS24650	COG2942	2-epimerase
ECO111_RS24655	COG3684	Belongs to the aldolase LacD family
ECO111_RS24660	COG2084	Dehydrogenase
ECO111_RS24665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECO111_RS24670	COG1349	DNA-binding transcription factor activity
ECO111_RS24675	COG1011	Hydrolase
ECO111_RS24690	COG0456	acetyltransferase
ECO111_RS24700	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ECO111_RS24710	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECO111_RS24715	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECO111_RS24730	COG2864	formate dehydrogenase
ECO111_RS24735	COG0437	4 iron, 4 sulfur cluster binding
ECO111_RS24740	COG3383	formate dehydrogenase (NAD+) activity
ECO111_RS24740	COG0243	molybdopterin cofactor binding
ECO111_RS24745	COG0243	molybdopterin cofactor binding
ECO111_RS24745	COG3383	formate dehydrogenase (NAD+) activity
ECO111_RS24760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS24760	COG3711	transcriptional antiterminator
ECO111_RS24765	COG1363	Peptidase, m42
ECO111_RS24770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS24770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS24775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS24785	COG1454	alcohol dehydrogenase
ECO111_RS24825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ECO111_RS24840	COG2258	MOSC domain
ECO111_RS24845	COG2205	protein histidine kinase activity
ECO111_RS24850	COG0745	RESPONSE REGULATOR receiver
ECO111_RS24855	COG3678	ATP-independent chaperone mediated protein folding
ECO111_RS24870	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ECO111_RS24890	COG3152	Membrane
ECO111_RS24895	COG3691	Protein conserved in bacteria
ECO111_RS24900	COG0589	response to stress
ECO111_RS24910	COG1494	fructose-1,6-bisphosphatase
ECO111_RS24920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ECO111_RS24935	COG1575	Belongs to the MenA family. Type 1 subfamily
ECO111_RS24950	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECO111_RS24955	COG1609	Transcriptional regulator
ECO111_RS24960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ECO111_RS24970	COG3209	COG3209 Rhs family protein
ECO111_RS24995	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ECO111_RS25005	COG0626	cystathionine gamma-synthase activity
ECO111_RS25010	COG0527	aspartate kinase activity
ECO111_RS25010	COG0460	homoserine dehydrogenase
ECO111_RS25020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ECO111_RS25030	COG0697	spore germination
ECO111_RS25035	COG3738	Protein conserved in bacteria
ECO111_RS25045	COG0371	Dehydrogenase
ECO111_RS25050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECO111_RS25055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS25055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECO111_RS25055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECO111_RS25060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS25065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS25070	COG1882	Formate acetyltransferase
ECO111_RS25075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECO111_RS25080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECO111_RS25085	COG2207	Transcriptional regulator
ECO111_RS25090	COG2194	sulfuric ester hydrolase activity
ECO111_RS25105	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ECO111_RS25120	COG0583	DNA-binding transcription factor activity
ECO111_RS25180	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ECO111_RS25180	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ECO111_RS25220	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECO111_RS25225	COG0250	Participates in transcription elongation, termination and antitermination
ECO111_RS25265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ECO111_RS25275	COG2104	thiamine diphosphate biosynthetic process
ECO111_RS25280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECO111_RS25315	COG3068	Protein conserved in bacteria
ECO111_RS25330	COG3678	ATP-independent chaperone mediated protein folding
ECO111_RS25335	COG4191	Histidine kinase
ECO111_RS25340	COG2204	response regulator
ECO111_RS25345	COG0151	Belongs to the GarS family
ECO111_RS25375	COG0456	acetyltransferase
ECO111_RS25385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECO111_RS25390	COG2224	Isocitrate lyase
ECO111_RS25405	COG1414	Transcriptional regulator
ECO111_RS25410	COG0646	methionine synthase
ECO111_RS25410	COG1410	methionine synthase
ECO111_RS25415	COG1283	sodium-dependent phosphate transmembrane transporter activity
ECO111_RS25480	COG3541	Predicted nucleotidyltransferase
ECO111_RS25485	COG0542	response to heat
ECO111_RS25490	COG0527	aspartate kinase activity
ECO111_RS25515	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECO111_RS25535	COG0477	Major facilitator Superfamily
ECO111_RS25535	COG2814	Major facilitator Superfamily
ECO111_RS25540	COG3833	ABC-type maltose transport systems, permease component
ECO111_RS25545	COG1175	transmembrane transport
ECO111_RS25550	COG2182	Extracellular solute-binding protein
ECO111_RS25560	COG3842	ATPase activity
ECO111_RS25580	COG1357	PFAM Pentapeptide repeats (8 copies)
ECO111_RS25600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ECO111_RS25610	COG0534	Mate efflux family protein
ECO111_RS25615	COG3237	CsbD-like
ECO111_RS25620	COG0735	belongs to the Fur family
ECO111_RS25675	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ECO111_RS25680	COG5532	Uncharacterized conserved protein (DUF2303)
ECO111_RS25715	COG1403	HNH endonuclease
ECO111_RS25720	COG0484	heat shock protein binding
ECO111_RS25760	COG3772	lysozyme
ECO111_RS25885	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECO111_RS25930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECO111_RS25940	COG0604	alcohol dehydrogenase
ECO111_RS25945	COG0305	Participates in initiation and elongation during chromosome replication
ECO111_RS25950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECO111_RS25955	COG1448	Aminotransferase
ECO111_RS25965	COG3700	Belongs to the class B bacterial acid phosphatase family
ECO111_RS25970	COG0432	Pfam Uncharacterised protein family UPF0047
ECO111_RS25975	COG2315	Protein conserved in bacteria
ECO111_RS25980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ECO111_RS25985	COG0629	single-stranded DNA binding
ECO111_RS25995	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECO111_RS26000	COG2207	Transcriptional regulator
ECO111_RS26005	COG0789	Transcriptional regulator
ECO111_RS26010	COG2252	PERMEase
ECO111_RS26015	COG0025	NhaP-type Na H and K H
ECO111_RS26030	COG3162	membrane
ECO111_RS26035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ECO111_RS26045	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ECO111_RS26050	COG0437	4 iron, 4 sulfur cluster binding
ECO111_RS26055	COG3301	Polysulphide reductase, NrfD
ECO111_RS26060	COG1138	Cytochrome C-type biogenesis protein
ECO111_RS26065	COG3088	subunit of a heme lyase
ECO111_RS26070	COG4235	cytochrome complex assembly
ECO111_RS26075	COG1301	dicarboxylic acid transport
ECO111_RS26080	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECO111_RS26085	COG3383	formate dehydrogenase (NAD+) activity
ECO111_RS26090	COG3383	formate dehydrogenase (NAD+) activity
ECO111_RS26100	COG1289	transmembrane transporter activity
ECO111_RS26105	COG1566	PFAM secretion protein HlyD family protein
ECO111_RS26115	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ECO111_RS26120	COG0698	ribose 5-phosphate isomerase
ECO111_RS26130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ECO111_RS26135	COG0456	acetyltransferase
ECO111_RS26140	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ECO111_RS26145	COG3454	Phosphonate metabolism
ECO111_RS26150	COG4778	phosphonate C-P lyase system protein PhnL
ECO111_RS26155	COG4107	phosphonate C-P lyase system protein PhnK
ECO111_RS26160	COG3627	carbon phosphorus lyase activity
ECO111_RS26165	COG3626	phosphonate metabolism
ECO111_RS26170	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ECO111_RS26175	COG3624	Phosphonate C-P lyase system protein PhnG
ECO111_RS26180	COG2188	Transcriptional regulator
ECO111_RS26185	COG3639	organic phosphonate transmembrane transporter activity
ECO111_RS26190	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ECO111_RS26200	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ECO111_RS26205	COG2824	Alkylphosphonate utilization operon protein PhnA
ECO111_RS26210	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ECO111_RS26220	COG0477	Major facilitator Superfamily
ECO111_RS26230	COG0642	Histidine kinase
ECO111_RS26235	COG0745	RESPONSE REGULATOR receiver
ECO111_RS26240	COG2194	sulfuric ester hydrolase activity
ECO111_RS26245	COG0531	amino acid
ECO111_RS26250	COG2207	Transcriptional regulator
ECO111_RS26255	COG1982	Orn Lys Arg decarboxylase major
ECO111_RS26260	COG2169	Transcriptional regulator
ECO111_RS26270	COG1486	melibiose metabolic process
ECO111_RS26275	COG2211	Major facilitator Superfamily
ECO111_RS26280	COG3647	Membrane
ECO111_RS26285	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECO111_RS26285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECO111_RS26290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECO111_RS26300	COG4565	transcriptional regulatory protein
ECO111_RS26305	COG3290	protein histidine kinase activity
ECO111_RS26310	COG3592	Divergent 4Fe-4S mono-cluster
ECO111_RS26315	COG2388	GCN5-related N-acetyl-transferase
ECO111_RS26335	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ECO111_RS26390	COG0675	Transposase, IS605 OrfB family
ECO111_RS26410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ECO111_RS26460	COG3037	sugar-specific permease SgaT UlaA
ECO111_RS26475	COG1073	alpha beta
ECO111_RS26480	COG3650	response to hydrogen peroxide
ECO111_RS26490	COG1960	acyl-CoA dehydrogenase activity
ECO111_RS26495	COG0754	glutathionylspermidine amidase activity
ECO111_RS26500	COG5463	Belongs to the UPF0441 family
ECO111_RS26505	COG3766	membrane
ECO111_RS26515	COG1842	Phage shock protein A
ECO111_RS26520	COG3789	protein conserved in bacteria
ECO111_RS26525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECO111_RS26530	COG0557	exoribonuclease II activity
ECO111_RS26545	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ECO111_RS26550	COG0330	HflC and HflK could
ECO111_RS26555	COG0330	HflC and HflK could
ECO111_RS26560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ECO111_RS26580	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECO111_RS26585	COG0802	atpase or kinase
ECO111_RS26590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ECO111_RS26590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ECO111_RS26630	COG3264	Mechanosensitive ion channel
ECO111_RS26630	COG1511	domain protein
ECO111_RS26645	COG0531	amino acid
ECO111_RS26655	COG1053	succinate dehydrogenase
ECO111_RS26660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECO111_RS26675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECO111_RS26680	COG3040	lipid binding
ECO111_RS26685	COG2076	Multidrug Resistance protein
ECO111_RS26690	COG5510	response to toxic substance
ECO111_RS26695	COG5510	response to toxic substance
ECO111_RS26705	COG1509	lysine 2,3-aminomutase activity
ECO111_RS26730	COG0531	amino acid
ECO111_RS26735	COG3030	protein affecting phage T7 exclusion by the F plasmid
ECO111_RS26740	COG1027	Aspartate ammonia-lyase
ECO111_RS26745	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECO111_RS26760	COG1309	transcriptional regulator
ECO111_RS26770	COG0582	viral genome integration into host DNA
ECO111_RS26775	COG4372	Transposase
ECO111_RS26790	COG3436	PFAM IS66 Orf2 family protein
ECO111_RS26835	COG0675	Transposase, IS605 OrfB family
ECO111_RS26840	COG3061	Opacity-associated protein A
ECO111_RS26845	COG0545	Peptidyl-prolyl cis-trans isomerase
ECO111_RS26850	COG1113	amino acid transport
ECO111_RS26870	COG0697	spore germination
ECO111_RS26875	COG0702	epimerase
ECO111_RS26880	COG1733	regulation of RNA biosynthetic process
ECO111_RS26885	COG0737	Belongs to the 5'-nucleotidase family
ECO111_RS26890	COG1218	3'(2'),5'-bisphosphate nucleotidase
ECO111_RS26895	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ECO111_RS26905	COG1253	flavin adenine dinucleotide binding
ECO111_RS26920	COG0729	surface antigen
ECO111_RS26925	COG2911	Protein conserved in bacteria
ECO111_RS26930	COG2105	PFAM AIG2 family protein
ECO111_RS26935	COG2336	PFAM SpoVT AbrB
ECO111_RS26940	COG2337	Toxic component of a toxin-antitoxin (TA) module
ECO111_RS26945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ECO111_RS26950	COG1879	ABC-type sugar transport system periplasmic component
ECO111_RS26955	COG1129	ABC transporter
ECO111_RS26960	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECO111_RS26975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ECO111_RS26985	COG0312	modulator of DNA gyrase
ECO111_RS26990	COG3783	Cytochrome b(562)
ECO111_RS26995	COG0602	queuosine metabolic process
ECO111_RS27000	COG1328	CTP reductase activity
ECO111_RS27005	COG0366	Alpha amylase catalytic
ECO111_RS27010	COG1263	PTS System
ECO111_RS27010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECO111_RS27015	COG1609	Transcriptional regulator
ECO111_RS27020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ECO111_RS27025	COG0251	oxidation-reduction process
ECO111_RS27050	COG0251	oxidation-reduction process
ECO111_RS27055	COG1028	Short-chain dehydrogenase reductase Sdr
ECO111_RS27060	COG1309	transcriptional regulator
ECO111_RS27065	COG2731	YhcH YjgK YiaL family protein
ECO111_RS27085	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ECO111_RS27090	COG0456	acetyltransferase
ECO111_RS27095	COG4269	membrane
ECO111_RS27100	COG0525	valine-tRNA ligase activity
ECO111_RS27105	COG2927	DNA polymerase III (CHI subunit)
ECO111_RS27115	COG0795	lipopolysaccharide-transporting ATPase activity
ECO111_RS27120	COG0795	lipopolysaccharide-transporting ATPase activity
ECO111_RS27125	COG0433	COG0433 Predicted ATPase
ECO111_RS27130	COG1064	alcohol dehydrogenase
ECO111_RS27140	COG0582	viral genome integration into host DNA
ECO111_RS27225	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECO111_RS27240	COG0582	viral genome integration into host DNA
ECO111_RS27245	COG4974	Belongs to the 'phage' integrase family
ECO111_RS27260	COG3539	Fimbrial protein
ECO111_RS27265	COG3121	Chaperone
ECO111_RS27270	COG3188	usher protein
ECO111_RS27280	COG3539	Fimbrial protein
ECO111_RS27285	COG3539	Fimbrial protein
ECO111_RS27290	COG3539	Fimbrial protein
ECO111_RS27295	COG2610	gluconate transmembrane transporter activity
ECO111_RS27310	COG0246	Mannitol dehydrogenase
ECO111_RS27320	COG2186	Transcriptional regulator
ECO111_RS27345	COG0583	DNA-binding transcription factor activity
ECO111_RS27350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECO111_RS27355	COG0700	Nucleoside recognition
ECO111_RS27360	COG3366	ferrous iron transmembrane transporter activity
ECO111_RS27370	COG0477	Major facilitator Superfamily
ECO111_RS27385	COG1924	4 iron, 4 sulfur cluster binding
ECO111_RS27390	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ECO111_RS27395	COG2733	membrane
ECO111_RS27400	COG2814	Major facilitator Superfamily
ECO111_RS27410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECO111_RS27415	COG5457	Domain of unknown function (DUF1127)
ECO111_RS27440	COG0523	cobalamin synthesis protein
ECO111_RS27445	COG2879	small protein
ECO111_RS27450	COG1966	Carbon starvation protein
ECO111_RS27460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ECO111_RS27465	COG2368	4-hydroxyphenylacetate
ECO111_RS27485	COG3971	2-oxopent-4-enoate hydratase activity
ECO111_RS27495	COG3384	dioxygenase
ECO111_RS27500	COG1012	belongs to the aldehyde dehydrogenase family
ECO111_RS27505	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECO111_RS27510	COG1846	Transcriptional regulator
ECO111_RS27515	COG0840	transmembrane signaling receptor activity
ECO111_RS27520	COG2271	Major facilitator Superfamily
ECO111_RS27525	COG1802	Transcriptional regulator
ECO111_RS27530	COG1063	alcohol dehydrogenase
ECO111_RS27545	COG1484	DNA-dependent DNA replication
ECO111_RS27560	COG2966	Psort location CytoplasmicMembrane, score
ECO111_RS27565	COG2197	response regulator
ECO111_RS27570	COG2197	response regulator
ECO111_RS27575	COG4114	ferric iron reductase
ECO111_RS27605	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ECO111_RS27610	COG0456	acetyltransferase
ECO111_RS27615	COG1011	Hydrolase
ECO111_RS27625	COG2823	Periplasmic or secreted lipoprotein
ECO111_RS27635	COG4667	esterase of the alpha-beta hydrolase superfamily
ECO111_RS27640	COG0084	hydrolase, TatD family'
ECO111_RS27645	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECO111_RS27650	COG1328	CTP reductase activity
ECO111_RS27690	COG3726	membrane protein affecting hemolysin expression
ECO111_RS27695	COG0560	Phosphoserine phosphatase
ECO111_RS27700	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ECO111_RS27705	COG1056	cytidyltransferase-related domain
ECO111_RS27705	COG3172	ATPase kinase involved in NAD metabolism
ECO111_RS27715	COG0488	(ABC) transporter
ECO111_RS27720	COG0741	lytic transglycosylase activity
ECO111_RS27740	COG2207	Transcriptional regulator
ECO111_RS27740	COG3708	Transcriptional regulator
ECO111_RS27745	COG3045	CreA protein
ECO111_RS27750	COG0745	RESPONSE REGULATOR receiver
ECO111_RS27755	COG2205	protein histidine kinase activity
ECO111_RS27760	COG4452	Inner membrane protein CreD
ECO111_RS27765	COG0745	RESPONSE REGULATOR receiver
ECO111_RS27775	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ECO111_RS27850	COG0527	aspartate kinase activity
ECO111_RS27850	COG0460	homoserine dehydrogenase
ECO111_RS28125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ECO111_RS28165	COG0417	DNA replication proofreading
ECO111_RS28215	COG0586	Pfam SNARE associated Golgi protein
ECO111_RS28310	COG0028	Belongs to the TPP enzyme family
ECO111_RS28350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECO111_RS28390	COG0772	Belongs to the SEDS family
ECO111_RS28525	COG2186	Transcriptional regulator
ECO111_RS28535	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ECO111_RS28695	COG0617	tRNA 3'-terminal CCA addition
ECO111_RS28700	COG0617	tRNA 3'-terminal CCA addition
ECO111_RS28860	COG2860	membrane
ECO111_RS28895	COG3835	regulator
ECO111_RS29000	COG0527	aspartate kinase activity
ECO111_RS29000	COG0460	homoserine dehydrogenase
ECO111_RS29365	COG4977	sequence-specific DNA binding
ECO111_RS29440	COG2814	Major facilitator Superfamily
ECO111_RS29510	COG0583	DNA-binding transcription factor activity
ECO111_RS29530	COG0028	Belongs to the TPP enzyme family
ECO111_RS29535	COG0028	Belongs to the TPP enzyme family
ECO111_RS29545	COG0028	Belongs to the TPP enzyme family
ECO111_RS29555	COG1609	Transcriptional regulator
ECO111_RS29830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ECO111_RS29835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ECO111_RS30135	COG0460	homoserine dehydrogenase
ECO111_RS30135	COG0527	aspartate kinase activity
ECO111_RS30140	COG0527	aspartate kinase activity
ECO111_RS30140	COG0460	homoserine dehydrogenase
ECO111_RS30190	COG5301	cellulose 1,4-beta-cellobiosidase activity