locus-tag	class	description
CGC46_RS00140	COG2116	formate transmembrane transporter activity
CGC46_RS00150	COG2853	Lipoprotein
CGC46_RS00165	COG2067	long-chain fatty acid transport protein
CGC46_RS00175	COG3691	Protein conserved in bacteria
CGC46_RS00190	COG2062	phosphohistidine phosphatase, SixA
CGC46_RS00195	COG3539	Fimbrial protein
CGC46_RS00205	COG3121	Chaperone
CGC46_RS00210	COG3539	Fimbrial protein
CGC46_RS00215	COG3539	Fimbrial protein
CGC46_RS00220	COG3539	Fimbrial protein
CGC46_RS00235	COG2890	protein-(glutamine-N5) methyltransferase activity
CGC46_RS00250	COG0730	response to heat
CGC46_RS00255	COG3101	peptidyl-lysine hydroxylation
CGC46_RS00270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGC46_RS00280	COG2814	Major facilitator Superfamily
CGC46_RS00295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CGC46_RS00305	COG0586	Pfam SNARE associated Golgi protein
CGC46_RS00315	COG0285	dihydrofolate synthase activity
CGC46_RS00320	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CGC46_RS00325	COG1286	toxin biosynthetic process
CGC46_RS00330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CGC46_RS00335	COG0163	prenyltransferase activity
CGC46_RS00340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC46_RS00345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC46_RS00350	COG4215	(ABC) transporter
CGC46_RS00355	COG4160	amino acid transport
CGC46_RS00360	COG4598	ABC transporter
CGC46_RS00365	COG5464	transposase or invertase
CGC46_RS00370	COG1090	epimerase
CGC46_RS00375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CGC46_RS00380	COG0625	glutathione transferase activity
CGC46_RS00385	COG0625	glutathione transferase activity
CGC46_RS00390	COG0622	Phosphoesterase
CGC46_RS00395	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CGC46_RS00400	COG1288	antiporter activity
CGC46_RS00405	COG0280	phosphate acetyltransferase
CGC46_RS00405	COG0857	belongs to the CobB CobQ family
CGC46_RS00410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CGC46_RS00425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGC46_RS00430	COG0471	metal ion transport
CGC46_RS00430	COG0490	domain, Protein
CGC46_RS00440	COG0436	Aminotransferase
CGC46_RS00450	COG0583	DNA-binding transcription factor activity
CGC46_RS00470	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CGC46_RS00475	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CGC46_RS00480	COG1034	ATP synthesis coupled electron transport
CGC46_RS00495	COG0839	Belongs to the complex I subunit 6 family
CGC46_RS00505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CGC46_RS00510	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGC46_RS00540	COG2153	protein acetylation
CGC46_RS00545	COG4575	ribosome binding
CGC46_RS00550	COG1169	isochorismate synthase
CGC46_RS00565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CGC46_RS00575	COG0318	PFAM AMP-dependent synthetase and ligase
CGC46_RS00640	COG1414	Transcriptional regulator
CGC46_RS00650	COG2271	Major facilitator Superfamily
CGC46_RS00655	COG3836	Belongs to the HpcH HpaI aldolase family
CGC46_RS00660	COG5464	transposase or invertase
CGC46_RS00665	COG0247	lactate metabolic process
CGC46_RS00675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGC46_RS00680	COG2271	Major facilitator Superfamily
CGC46_RS00685	COG0584	glycerophosphoryl diester phosphodiesterase
CGC46_RS00690	COG0583	DNA-binding transcription factor activity
CGC46_RS00695	COG3642	lipopolysaccharide core region biosynthetic process
CGC46_RS00700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGC46_RS00705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGC46_RS00710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGC46_RS00720	COG3468	outer membrane autotransporter barrel domain protein
CGC46_RS00730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGC46_RS00735	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CGC46_RS00740	COG3234	Protein of unknown function (DUF1175)
CGC46_RS00745	COG2373	Large extracellular alpha-helical protein
CGC46_RS00750	COG5445	Predicted secreted protein (DUF2300)
CGC46_RS00755	COG4676	Protein conserved in bacteria
CGC46_RS00760	COG0183	Belongs to the thiolase family
CGC46_RS00765	COG2031	fatty acid transporter
CGC46_RS00770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CGC46_RS00775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGC46_RS00780	COG2204	response regulator
CGC46_RS00785	COG3852	Histidine kinase
CGC46_RS00790	COG0784	Response regulator, receiver
CGC46_RS00790	COG2205	protein histidine kinase activity
CGC46_RS00795	COG2197	response regulator
CGC46_RS00800	COG2198	Histidine kinase
CGC46_RS00800	COG0642	Histidine kinase
CGC46_RS00815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CGC46_RS00820	COG1477	protein flavinylation
CGC46_RS00825	COG2169	Transcriptional regulator
CGC46_RS00825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGC46_RS00830	COG3145	DNA-N1-methyladenine dioxygenase activity
CGC46_RS00835	COG4615	Cyclic peptide transporter
CGC46_RS00855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS00855	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS00860	COG3062	negative regulation of establishment of protein localization
CGC46_RS00870	COG0437	4 iron, 4 sulfur cluster binding
CGC46_RS00875	COG0348	domain, Protein
CGC46_RS00880	COG3043	anaerobic respiration
CGC46_RS00885	COG3005	denitrification pathway
CGC46_RS00895	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGC46_RS00900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGC46_RS00905	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGC46_RS00915	COG1138	Cytochrome C-type biogenesis protein
CGC46_RS00920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGC46_RS00925	COG4235	cytochrome complex assembly
CGC46_RS00925	COG3088	subunit of a heme lyase
CGC46_RS00930	COG2197	response regulator
CGC46_RS00940	COG3468	outer membrane autotransporter barrel domain protein
CGC46_RS00955	COG3083	sulfuric ester hydrolase activity
CGC46_RS00975	COG1061	Type III restriction enzyme res subunit
CGC46_RS00985	COG1187	pseudouridine synthase activity
CGC46_RS00990	COG2814	Major facilitator Superfamily
CGC46_RS01005	COG4172	Belongs to the ABC transporter superfamily
CGC46_RS01010	COG4239	(ABC) transporter, permease
CGC46_RS01015	COG4174	ABC transporter (Permease)
CGC46_RS01020	COG4166	transmembrane transport
CGC46_RS01025	COG2200	EAL domain
CGC46_RS01030	COG0791	NLP P60 protein
CGC46_RS01035	COG0671	phosphoesterase, PA-phosphatase related
CGC46_RS01040	COG0523	cobalamin synthesis protein
CGC46_RS01045	COG0246	Mannitol dehydrogenase
CGC46_RS01060	COG2814	Major facilitator Superfamily
CGC46_RS01065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS01065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS01070	COG1105	Belongs to the carbohydrate kinase PfkB family
CGC46_RS01075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS01075	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CGC46_RS01075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS01080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC46_RS01085	COG2313	pseudouridylate synthase activity
CGC46_RS01090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CGC46_RS01095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGC46_RS01105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CGC46_RS01110	COG1522	sequence-specific DNA binding
CGC46_RS01110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC46_RS01120	COG2855	membrane
CGC46_RS01125	COG0583	DNA-binding transcription factor activity
CGC46_RS01135	COG0833	amino acid
CGC46_RS01145	COG4771	TonB-dependent receptor
CGC46_RS01170	COG2311	Membrane
CGC46_RS01180	COG1609	Transcriptional regulator
CGC46_RS01185	COG1879	ABC-type sugar transport system periplasmic component
CGC46_RS01190	COG1129	ABC transporter
CGC46_RS01195	COG4211	Belongs to the binding-protein-dependent transport system permease family
CGC46_RS01200	COG0167	dihydroorotate dehydrogenase activity
CGC46_RS01200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CGC46_RS01205	COG0493	'glutamate synthase
CGC46_RS01215	COG2949	membrane
CGC46_RS01225	COG1346	cytolysis
CGC46_RS01235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGC46_RS01260	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS01265	COG0586	Pfam SNARE associated Golgi protein
CGC46_RS01275	COG1686	Belongs to the peptidase S11 family
CGC46_RS01280	COG0277	FAD linked oxidase domain protein
CGC46_RS01285	COG1472	Belongs to the glycosyl hydrolase 3 family
CGC46_RS01290	COG1732	Glycine betaine
CGC46_RS01295	COG1174	glycine betaine transport
CGC46_RS01300	COG1125	glycine betaine transport
CGC46_RS01305	COG1174	glycine betaine transport
CGC46_RS01315	COG0789	Transcriptional regulator
CGC46_RS01320	COG3275	phosphorelay sensor kinase activity
CGC46_RS01325	COG3279	Response regulator of the LytR AlgR family
CGC46_RS01330	COG4807	Protein conserved in bacteria
CGC46_RS01335	COG4808	Protein conserved in bacteria
CGC46_RS01340	COG4715	Zinc finger, swim domain protein
CGC46_RS01345	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CGC46_RS01350	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CGC46_RS01355	COG0714	Associated with various cellular activities
CGC46_RS01370	COG3831	ATPase activity
CGC46_RS01380	COG3831	ATPase activity
CGC46_RS01390	COG0489	protein tyrosine kinase activity
CGC46_RS01405	COG3539	Fimbrial protein
CGC46_RS01410	COG3121	Chaperone
CGC46_RS01415	COG3188	usher protein
CGC46_RS01420	COG3539	Fimbrial protein
CGC46_RS01425	COG5455	response to cobalt ion
CGC46_RS01430	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CGC46_RS01445	COG0351	phosphomethylpyrimidine kinase
CGC46_RS01450	COG3757	hydrolase, family 25
CGC46_RS01455	COG2188	Transcriptional regulator
CGC46_RS01460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC46_RS01465	COG1397	ADP-ribosylglycohydrolase
CGC46_RS01470	COG2211	Major facilitator Superfamily
CGC46_RS01475	COG1830	Aldolase
CGC46_RS01490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS01495	COG3414	Phosphotransferase system galactitol-specific IIB component
CGC46_RS01500	COG3775	system Galactitol-specific IIC component
CGC46_RS01505	COG1063	alcohol dehydrogenase
CGC46_RS01530	COG0826	peptidase U32
CGC46_RS01540	COG3609	addiction module antidote protein, CC2985 family
CGC46_RS01550	COG0745	RESPONSE REGULATOR receiver
CGC46_RS01555	COG2205	protein histidine kinase activity
CGC46_RS01600	COG4245	von Willebrand factor, type A
CGC46_RS01605	COG0631	protein serine/threonine phosphatase activity
CGC46_RS01610	COG3779	Protein conserved in bacteria
CGC46_RS01615	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CGC46_RS01620	COG0443	Heat shock 70 kDa protein
CGC46_RS01625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CGC46_RS01630	COG5001	Diguanylate cyclase
CGC46_RS01630	COG3447	MASE1 domain protein
CGC46_RS01630	COG5002	protein histidine kinase activity
CGC46_RS01635	COG0572	uridine kinase
CGC46_RS01645	COG2982	Protein involved in outer membrane biogenesis
CGC46_RS01650	COG1253	flavin adenine dinucleotide binding
CGC46_RS01655	COG1596	polysaccharide export
CGC46_RS01660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGC46_RS01665	COG3206	protein involved in exopolysaccharide biosynthesis
CGC46_RS01665	COG0489	protein tyrosine kinase activity
CGC46_RS01670	COG0463	Glycosyl transferase, family 2
CGC46_RS01675	COG1045	serine acetyltransferase
CGC46_RS01680	COG0438	transferase activity, transferring glycosyl groups
CGC46_RS01690	COG1216	Glycosyl transferase, family 2
CGC46_RS01695	COG0110	maltose O-acetyltransferase activity
CGC46_RS01700	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CGC46_RS01705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGC46_RS01710	COG1051	belongs to the nudix hydrolase family
CGC46_RS01715	COG0297	glycogen (starch) synthase activity
CGC46_RS01720	COG0662	Cupin 2, conserved barrel domain protein
CGC46_RS01720	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CGC46_RS01725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGC46_RS01730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CGC46_RS01735	COG2244	polysaccharide biosynthetic process
CGC46_RS01740	COG2327	Polysaccharide pyruvyl transferase
CGC46_RS01745	COG0438	transferase activity, transferring glycosyl groups
CGC46_RS01755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGC46_RS01760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CGC46_RS01775	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CGC46_RS01800	COG1215	transferase activity, transferring glycosyl groups
CGC46_RS01815	COG0367	asparagine synthase
CGC46_RS01820	COG0438	transferase activity, transferring glycosyl groups
CGC46_RS01825	COG0438	transferase activity, transferring glycosyl groups
CGC46_RS01830	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CGC46_RS01835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGC46_RS01840	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CGC46_RS01860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CGC46_RS01865	COG0131	Imidazoleglycerol-phosphate dehydratase
CGC46_RS01865	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CGC46_RS01875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CGC46_RS01895	COG2161	toxin-antitoxin pair type II binding
CGC46_RS01900	COG4115	mRNA cleavage
CGC46_RS01905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGC46_RS01910	COG0583	DNA-binding transcription factor activity
CGC46_RS01920	COG0531	amino acid
CGC46_RS01925	COG2391	methyltransferase activity
CGC46_RS01930	COG0425	Belongs to the sulfur carrier protein TusA family
CGC46_RS01935	COG2925	Exonuclease
CGC46_RS01940	COG1686	Belongs to the peptidase S11 family
CGC46_RS01950	COG1289	transmembrane transporter activity
CGC46_RS01975	COG4656	Part of a membrane complex involved in electron transport
CGC46_RS01980	COG1454	alcohol dehydrogenase
CGC46_RS01980	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS01995	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CGC46_RS02010	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CGC46_RS02070	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CGC46_RS02085	COG1376	ErfK ybiS ycfS ynhG family protein
CGC46_RS02095	COG0583	DNA-binding transcription factor activity
CGC46_RS02100	COG0583	DNA-binding transcription factor activity
CGC46_RS02140	COG0582	viral genome integration into host DNA
CGC46_RS02150	COG0534	Mate efflux family protein
CGC46_RS02170	COG0217	transcriptional regulatory protein
CGC46_RS02175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CGC46_RS02180	COG0477	Major facilitator Superfamily
CGC46_RS02200	COG1388	LysM domain
CGC46_RS02200	COG1470	cell adhesion involved in biofilm formation
CGC46_RS02285	COG3038	cytochrome b561
CGC46_RS02290	COG3443	Belongs to the bacterial solute-binding protein 9 family
CGC46_RS02305	COG2351	hydroxyisourate hydrolase activity
CGC46_RS02310	COG0745	RESPONSE REGULATOR receiver
CGC46_RS02315	COG2205	protein histidine kinase activity
CGC46_RS02330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CGC46_RS02340	COG1418	mRNA catabolic process
CGC46_RS02345	COG0270	DNA (cytosine-5-)-methyltransferase activity
CGC46_RS02350	COG3727	T/G mismatch-specific endonuclease activity
CGC46_RS02355	COG0697	spore germination
CGC46_RS02360	COG2354	Protein conserved in bacteria
CGC46_RS02365	COG5475	Uncharacterized small protein (DUF2158)
CGC46_RS02400	COG2197	response regulator
CGC46_RS02405	COG1684	flagellar biosynthetic protein fliR
CGC46_RS02410	COG1987	bacterial-type flagellum assembly
CGC46_RS02415	COG1338	Plays a role in the flagellum-specific transport system
CGC46_RS02420	COG3190	flagellar
CGC46_RS02425	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CGC46_RS02430	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CGC46_RS02435	COG1580	Controls the rotational direction of flagella during chemotaxis
CGC46_RS02440	COG3144	bacterial-type flagellum assembly
CGC46_RS02445	COG2882	bacterial-type flagellum organization
CGC46_RS02450	COG1157	protein secretion by the type III secretion system
CGC46_RS02455	COG1317	bacterial-type flagellum organization
CGC46_RS02460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CGC46_RS02465	COG1766	The M ring may be actively involved in energy transduction
CGC46_RS02480	COG2135	peptidase activity
CGC46_RS02485	COG0425	Belongs to the sulfur carrier protein TusA family
CGC46_RS02490	COG2391	methyltransferase activity
CGC46_RS02505	COG0366	Alpha amylase catalytic
CGC46_RS02515	COG1516	flagellar protein fliS
CGC46_RS02520	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CGC46_RS02535	COG1191	sigma factor activity
CGC46_RS02545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC46_RS02555	COG0765	amino acid transport
CGC46_RS02560	COG1126	abc transporter atp-binding protein
CGC46_RS02565	COG2197	response regulator
CGC46_RS02580	COG2197	response regulator
CGC46_RS02670	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CGC46_RS02675	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS02675	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS02760	COG4695	Portal protein
CGC46_RS02870	COG4974	Belongs to the 'phage' integrase family
CGC46_RS02875	COG3012	SEC-C Motif Domain Protein
CGC46_RS02875	COG3318	Belongs to the UPF0149 family
CGC46_RS02880	COG0814	amino acid
CGC46_RS02890	COG1528	Iron-storage protein
CGC46_RS02910	COG1528	Iron-storage protein
CGC46_RS02920	COG1879	ABC-type sugar transport system periplasmic component
CGC46_RS02925	COG1129	ABC transporter
CGC46_RS02930	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGC46_RS02935	COG1877	trehalose-phosphatase activity
CGC46_RS02945	COG0589	response to stress
CGC46_RS02960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CGC46_RS02965	COG1360	Flagellar Motor Protein
CGC46_RS02970	COG0643	Histidine kinase
CGC46_RS02970	COG2198	Histidine kinase
CGC46_RS02975	COG0835	chemotaxis
CGC46_RS02980	COG0840	transmembrane signaling receptor activity
CGC46_RS02985	COG0840	transmembrane signaling receptor activity
CGC46_RS02990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CGC46_RS02995	COG2201	protein-glutamate methylesterase activity
CGC46_RS03000	COG0745	RESPONSE REGULATOR receiver
CGC46_RS03005	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CGC46_RS03010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CGC46_RS03015	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CGC46_RS03025	COG3755	Protein conserved in bacteria
CGC46_RS03030	COG4372	Transposase
CGC46_RS03035	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS03045	COG4372	Transposase
CGC46_RS03050	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS03070	COG3102	Protein conserved in bacteria
CGC46_RS03080	COG3005	denitrification pathway
CGC46_RS03085	COG0243	molybdopterin cofactor binding
CGC46_RS03100	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CGC46_RS03105	COG1801	Protein of unknown function DUF72
CGC46_RS03110	COG1335	isochorismatase
CGC46_RS03120	COG0494	nUDIX hydrolase
CGC46_RS03125	COG0217	transcriptional regulatory protein
CGC46_RS03155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CGC46_RS03165	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CGC46_RS03170	COG0739	heme binding
CGC46_RS03175	COG1560	Kdo2-lipid A biosynthetic process
CGC46_RS03180	COG0469	pyruvate kinase activity
CGC46_RS03185	COG1737	Transcriptional regulator
CGC46_RS03190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CGC46_RS03195	COG0129	dihydroxy-acid dehydratase activity
CGC46_RS03200	COG0800	Aldolase
CGC46_RS03210	COG3141	response to X-ray
CGC46_RS03220	COG2979	Protein of unknown function (DUF533)
CGC46_RS03225	COG1770	oligopeptidase
CGC46_RS03230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CGC46_RS03235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGC46_RS03245	COG2372	response to copper ion
CGC46_RS03250	COG1276	copper resistance
CGC46_RS03260	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CGC46_RS03280	COG3008	intermembrane lipid transfer
CGC46_RS03285	COG2995	paraquat-inducible protein a
CGC46_RS03290	COG1956	GAF domain-containing protein
CGC46_RS03300	COG0793	Belongs to the peptidase S41A family
CGC46_RS03310	COG2814	Major facilitator Superfamily
CGC46_RS03315	COG1414	Transcriptional regulator
CGC46_RS03350	COG2226	methyltransferase
CGC46_RS03370	COG3716	PTS system mannose fructose sorbose family IID component
CGC46_RS03375	COG3715	PTS system
CGC46_RS03380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS03380	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS03395	COG1253	flavin adenine dinucleotide binding
CGC46_RS03405	COG1760	l-serine dehydratase
CGC46_RS03415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CGC46_RS03430	COG0251	oxidation-reduction process
CGC46_RS03435	COG1199	ATP-dependent helicase activity
CGC46_RS03440	COG1214	PFAM Peptidase M22, glycoprotease
CGC46_RS03445	COG3065	identical protein binding
CGC46_RS03450	COG0318	PFAM AMP-dependent synthetase and ligase
CGC46_RS03455	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CGC46_RS03460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGC46_RS03465	COG4638	Rieske (2fe-2S)
CGC46_RS03470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CGC46_RS03475	COG0473	3-isopropylmalate dehydrogenase activity
CGC46_RS03480	COG0583	DNA-binding transcription factor activity
CGC46_RS03490	COG3615	Tellurite resistance protein tehB
CGC46_RS03500	COG2261	transglycosylase associated protein
CGC46_RS03515	COG2199	diguanylate cyclase activity
CGC46_RS03515	COG2203	Gaf domain
CGC46_RS03520	COG3042	response to heat
CGC46_RS03530	COG2807	transmembrane transport
CGC46_RS03535	COG2207	Transcriptional regulator
CGC46_RS03550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGC46_RS03555	COG2199	diguanylate cyclase activity
CGC46_RS03560	COG2199	diguanylate cyclase activity
CGC46_RS03570	COG2766	serine protein kinase
CGC46_RS03575	COG3713	MltA-interacting MipA family protein
CGC46_RS03580	COG0656	L-ascorbic acid biosynthetic process
CGC46_RS03585	COG0676	glucose-6-phosphate 1-epimerase activity
CGC46_RS03590	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CGC46_RS03600	COG3139	Protein of unknown function (DUF1315)
CGC46_RS03605	COG1063	alcohol dehydrogenase
CGC46_RS03610	COG2271	Major facilitator Superfamily
CGC46_RS03615	COG1063	alcohol dehydrogenase
CGC46_RS03620	COG0191	fructose-bisphosphate aldolase activity
CGC46_RS03625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC46_RS03630	COG0667	Aldo Keto reductase
CGC46_RS03635	COG1349	DNA-binding transcription factor activity
CGC46_RS03640	COG2814	Major facilitator Superfamily
CGC46_RS03645	COG1335	isochorismatase
CGC46_RS03650	COG0252	asparaginase activity
CGC46_RS03655	COG0616	signal peptide processing
CGC46_RS03665	COG0778	Nitroreductase
CGC46_RS03680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGC46_RS03690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CGC46_RS03700	COG0494	nUDIX hydrolase
CGC46_RS03705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGC46_RS03710	COG2897	thiosulfate sulfurtransferase activity
CGC46_RS03715	COG4136	ATPase activity
CGC46_RS03720	COG4135	transport system, permease component
CGC46_RS03725	COG4134	Bacterial extracellular solute-binding protein
CGC46_RS03730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGC46_RS03735	COG0398	Pfam SNARE associated Golgi protein
CGC46_RS03745	COG0398	Pfam SNARE associated Golgi protein
CGC46_RS03750	COG0708	Exodeoxyribonuclease III
CGC46_RS03785	COG3678	ATP-independent chaperone mediated protein folding
CGC46_RS03795	COG0322	excinuclease ABC activity
CGC46_RS03805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CGC46_RS03815	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CGC46_RS03820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CGC46_RS03825	COG1447	Phosphotransferase system cellobiose-specific component IIA
CGC46_RS03830	COG1917	Cupin 2, conserved barrel domain protein
CGC46_RS03830	COG2169	Transcriptional regulator
CGC46_RS03835	COG1486	melibiose metabolic process
CGC46_RS03845	COG0753	catalase activity
CGC46_RS03860	COG1823	symporter activity
CGC46_RS03865	COG1988	membrane-bound metal-dependent
CGC46_RS03870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGC46_RS03880	COG3001	Fructosamine kinase
CGC46_RS03890	COG1105	Belongs to the carbohydrate kinase PfkB family
CGC46_RS03895	COG3137	Salt-induced outer membrane protein
CGC46_RS03955	COG0386	Belongs to the glutathione peroxidase family
CGC46_RS03965	COG0791	NLP P60 protein
CGC46_RS03970	COG2200	EAL domain
CGC46_RS03980	COG4256	Hemin uptake protein
CGC46_RS03985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CGC46_RS04000	COG0574	Belongs to the PEP-utilizing enzyme family
CGC46_RS04000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGC46_RS04005	COG0318	PFAM AMP-dependent synthetase and ligase
CGC46_RS04010	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CGC46_RS04015	COG0644	oxidoreductase
CGC46_RS04020	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CGC46_RS04025	COG2086	electron transfer activity
CGC46_RS04035	COG1917	Cupin 2, conserved barrel domain protein
CGC46_RS04035	COG2207	Transcriptional regulator
CGC46_RS04040	COG1960	acyl-CoA dehydrogenase activity
CGC46_RS04045	COG4670	ketone body catabolic process
CGC46_RS04065	COG0738	Major facilitator superfamily
CGC46_RS04080	COG0628	permease
CGC46_RS04090	COG0247	lactate metabolic process
CGC46_RS04090	COG0277	FAD linked oxidase domain protein
CGC46_RS04095	COG2050	protein possibly involved in aromatic compounds catabolism
CGC46_RS04105	COG0316	Belongs to the HesB IscA family
CGC46_RS04110	COG0719	Fe-S assembly protein
CGC46_RS04115	COG0396	ATPase activity
CGC46_RS04120	COG0719	Fe-S assembly protein
CGC46_RS04135	COG1376	ErfK ybiS ycfS ynhG family protein
CGC46_RS04140	COG4238	major outer membrane lipoprotein
CGC46_RS04145	COG0469	pyruvate kinase activity
CGC46_RS04155	COG0437	4 iron, 4 sulfur cluster binding
CGC46_RS04160	COG2414	aldehyde ferredoxin oxidoreductase
CGC46_RS04170	COG0437	4 iron, 4 sulfur cluster binding
CGC46_RS04175	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CGC46_RS04185	COG4529	Protein conserved in bacteria
CGC46_RS04205	COG3468	outer membrane autotransporter barrel domain protein
CGC46_RS04215	COG0307	riboflavin synthase, alpha
CGC46_RS04220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CGC46_RS04225	COG2814	Major facilitator Superfamily
CGC46_RS04230	COG0583	DNA-binding transcription factor activity
CGC46_RS04250	COG2814	Major facilitator Superfamily
CGC46_RS04255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CGC46_RS04260	COG0791	NLP P60 protein
CGC46_RS04265	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CGC46_RS04270	COG1201	RNA secondary structure unwinding
CGC46_RS04280	COG0346	lactoylglutathione lyase activity
CGC46_RS04285	COG1902	pentaerythritol trinitrate reductase activity
CGC46_RS04290	COG1309	transcriptional regulator
CGC46_RS04295	COG3313	Fe-S protein
CGC46_RS04300	COG4989	oxidoreductase activity
CGC46_RS04305	COG2032	superoxide dismutase activity
CGC46_RS04315	COG1566	PFAM secretion protein HlyD family protein
CGC46_RS04330	COG3133	Outer membrane lipoprotein
CGC46_RS04340	COG3895	Periplasmic Protein
CGC46_RS04355	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CGC46_RS04360	COG0625	glutathione transferase activity
CGC46_RS04365	COG3104	oligopeptide transport
CGC46_RS04375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CGC46_RS04385	COG4659	FMN binding
CGC46_RS04430	COG0673	inositol 2-dehydrogenase activity
CGC46_RS04440	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CGC46_RS04445	COG1263	PTS System
CGC46_RS04445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS04450	COG1609	Transcriptional regulator
CGC46_RS04455	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS04460	COG1309	transcriptional regulator
CGC46_RS04465	COG3250	beta-galactosidase activity
CGC46_RS04480	COG5339	Protein conserved in bacteria
CGC46_RS04485	COG1482	cell wall glycoprotein biosynthetic process
CGC46_RS04490	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CGC46_RS04490	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CGC46_RS04495	COG0114	fumarate hydratase activity
CGC46_RS04505	COG2205	protein histidine kinase activity
CGC46_RS04510	COG0745	RESPONSE REGULATOR receiver
CGC46_RS04515	COG3136	membrane protein required for alginate biosynthesis
CGC46_RS04525	COG0531	amino acid
CGC46_RS04540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CGC46_RS04545	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CGC46_RS04550	COG0628	permease
CGC46_RS04570	COG3591	Belongs to the peptidase S1B family
CGC46_RS04590	COG2814	Major facilitator Superfamily
CGC46_RS04595	COG0583	DNA-binding transcription factor activity
CGC46_RS04600	COG1940	carbohydrate kinase activity
CGC46_RS04605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CGC46_RS04615	COG3381	protein complex oligomerization
CGC46_RS04620	COG3302	dmso reductase anchor subunit
CGC46_RS04625	COG0437	4 iron, 4 sulfur cluster binding
CGC46_RS04630	COG0243	molybdopterin cofactor binding
CGC46_RS04635	COG0243	molybdopterin cofactor binding
CGC46_RS04650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGC46_RS04670	COG4948	Mandelate Racemase Muconate Lactonizing
CGC46_RS04675	COG1063	alcohol dehydrogenase
CGC46_RS04685	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS04690	COG4372	Transposase
CGC46_RS04695	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS04700	COG4372	Transposase
CGC46_RS04730	COG1403	HNH endonuclease
CGC46_RS04735	COG0484	heat shock protein binding
CGC46_RS04745	COG1278	Cold shock
CGC46_RS04750	COG1278	Cold shock
CGC46_RS04765	COG3772	lysozyme
CGC46_RS04775	COG1278	Cold shock
CGC46_RS04795	COG5562	phage envelope protein
CGC46_RS04820	COG0582	viral genome integration into host DNA
CGC46_RS04880	COG0740	serine-type endopeptidase activity
CGC46_RS04985	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS04990	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CGC46_RS05005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CGC46_RS05015	COG0582	viral genome integration into host DNA
CGC46_RS05035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CGC46_RS05100	COG1846	Transcriptional regulator
CGC46_RS05135	COG3111	PFAM Bacterial OB fold (BOF) protein
CGC46_RS05145	COG1403	HNH endonuclease
CGC46_RS05150	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CGC46_RS05165	COG2207	Transcriptional regulator
CGC46_RS05215	COG3772	lysozyme
CGC46_RS05250	COG4220	transposase activity
CGC46_RS05270	COG1030	water channel activity
CGC46_RS05355	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS05385	COG0477	Major facilitator Superfamily
CGC46_RS05400	COG1802	Transcriptional regulator
CGC46_RS05405	COG4221	oxidoreductase activity
CGC46_RS05415	COG0339	signal peptide processing
CGC46_RS05420	COG1546	Belongs to the CinA family
CGC46_RS05425	COG3111	PFAM Bacterial OB fold (BOF) protein
CGC46_RS05430	COG3706	GGDEF domain
CGC46_RS05440	COG2814	Major facilitator Superfamily
CGC46_RS05445	COG0697	spore germination
CGC46_RS05450	COG2188	Transcriptional regulator
CGC46_RS05460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CGC46_RS05465	COG1447	Phosphotransferase system cellobiose-specific component IIA
CGC46_RS05495	COG4977	sequence-specific DNA binding
CGC46_RS05500	COG1846	Transcriptional regulator
CGC46_RS05520	COG0583	DNA-binding transcription factor activity
CGC46_RS05525	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS05530	COG2066	Belongs to the glutaminase family
CGC46_RS05545	COG2199	diguanylate cyclase activity
CGC46_RS05565	COG3781	membrane
CGC46_RS05615	COG3210	domain, Protein
CGC46_RS05615	COG2911	Protein conserved in bacteria
CGC46_RS05625	COG1396	sequence-specific DNA binding
CGC46_RS05630	COG3550	peptidyl-serine autophosphorylation
CGC46_RS05635	COG4977	sequence-specific DNA binding
CGC46_RS05645	COG3539	Fimbrial protein
CGC46_RS05650	COG3121	Chaperone
CGC46_RS05655	COG3188	usher protein
CGC46_RS05660	COG3539	Fimbrial protein
CGC46_RS05665	COG3539	Fimbrial protein
CGC46_RS05670	COG3539	Fimbrial protein
CGC46_RS05675	COG0243	molybdopterin cofactor binding
CGC46_RS05685	COG2207	Transcriptional regulator
CGC46_RS05695	COG0641	radical SAM
CGC46_RS05700	COG4178	(ABC) transporter
CGC46_RS05705	COG4771	TonB-dependent receptor
CGC46_RS05710	COG0612	Peptidase, M16
CGC46_RS05715	COG0076	glutamate decarboxylase activity
CGC46_RS05720	COG0531	amino acid
CGC46_RS05725	COG1649	PFAM Uncharacterised BCR, COG1649
CGC46_RS05735	COG2199	diguanylate cyclase activity
CGC46_RS05735	COG2200	EAL domain
CGC46_RS05735	COG2202	Pas domain
CGC46_RS05740	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CGC46_RS05745	COG0747	negative chemotaxis
CGC46_RS05750	COG0601	transmembrane transport
CGC46_RS05755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGC46_RS05760	COG0444	Belongs to the ABC transporter superfamily
CGC46_RS05765	COG4608	Belongs to the ABC transporter superfamily
CGC46_RS05770	COG1764	response to oxidative stress
CGC46_RS05795	COG1064	alcohol dehydrogenase
CGC46_RS05800	COG3093	addiction module antidote protein HigA
CGC46_RS05805	COG2864	formate dehydrogenase
CGC46_RS05810	COG0437	4 iron, 4 sulfur cluster binding
CGC46_RS05820	COG0697	spore germination
CGC46_RS05825	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CGC46_RS05835	COG2223	nitrite transmembrane transporter activity
CGC46_RS05840	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGC46_RS05845	COG1140	nitrate reductase beta subunit
CGC46_RS05850	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CGC46_RS05855	COG2181	nitrate reductase activity
CGC46_RS05860	COG0384	phenazine biosynthesis protein PhzF
CGC46_RS05865	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CGC46_RS05870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGC46_RS05880	COG5433	transposase activity
CGC46_RS05885	COG5433	transposase activity
CGC46_RS05910	COG0625	glutathione transferase activity
CGC46_RS05920	COG3391	amine dehydrogenase activity
CGC46_RS05930	COG4772	TonB-dependent receptor
CGC46_RS05935	COG1802	Transcriptional regulator
CGC46_RS05940	COG2130	NADP-dependent
CGC46_RS05950	COG1247	-acetyltransferase
CGC46_RS05955	COG3238	Protein conserved in bacteria
CGC46_RS05990	COG1177	transmembrane transport
CGC46_RS05995	COG1176	ABC-type spermidine putrescine transport system, permease component I
CGC46_RS06000	COG3842	ATPase activity
CGC46_RS06005	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CGC46_RS06010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGC46_RS06015	COG1598	PFAM Uncharacterised protein family UPF0150
CGC46_RS06020	COG1724	mRNA binding
CGC46_RS06030	COG0826	peptidase U32
CGC46_RS06035	COG1396	sequence-specific DNA binding
CGC46_RS06040	COG3135	benzoate transporter
CGC46_RS06045	COG0675	Transposase, IS605 OrfB family
CGC46_RS06065	COG0500	methyltransferase
CGC46_RS06070	COG1275	C4-dicarboxylate transporter malic acid transport protein
CGC46_RS06075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CGC46_RS06080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGC46_RS06085	COG2841	Protein conserved in bacteria
CGC46_RS06105	COG5383	Protein conserved in bacteria
CGC46_RS06110	COG0583	DNA-binding transcription factor activity
CGC46_RS06115	COG0840	transmembrane signaling receptor activity
CGC46_RS06130	COG3038	cytochrome b561
CGC46_RS06135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CGC46_RS06140	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS06145	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CGC46_RS06150	COG1643	Atp-dependent helicase
CGC46_RS06160	COG0671	phosphoesterase, PA-phosphatase related
CGC46_RS06160	COG2453	phosphatase
CGC46_RS06170	COG4589	Belongs to the CDS family
CGC46_RS06175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGC46_RS06190	COG0667	Aldo Keto reductase
CGC46_RS06195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CGC46_RS06200	COG3327	negative regulation of DNA-templated transcription, initiation
CGC46_RS06205	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CGC46_RS06210	COG0183	Belongs to the thiolase family
CGC46_RS06215	COG2050	protein possibly involved in aromatic compounds catabolism
CGC46_RS06220	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGC46_RS06225	COG1024	Enoyl-CoA hydratase
CGC46_RS06230	COG1024	Enoyl-CoA hydratase
CGC46_RS06235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGC46_RS06240	COG2151	metal-sulfur cluster biosynthetic enzyme
CGC46_RS06245	COG3396	Phenylacetate-CoA oxygenase
CGC46_RS06250	COG3460	Phenylacetate-CoA oxygenase
CGC46_RS06255	COG3396	Phenylacetate-CoA oxygenase
CGC46_RS06260	COG2030	dehydratase
CGC46_RS06260	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS06265	COG3733	amine oxidase
CGC46_RS06270	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS06275	COG2207	Transcriptional regulator
CGC46_RS06280	COG3784	Protein of unknown function (DUF1318)
CGC46_RS06290	COG2911	Protein conserved in bacteria
CGC46_RS06295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGC46_RS06300	COG3187	Heat shock protein
CGC46_RS06305	COG3042	response to heat
CGC46_RS06310	COG0674	pyruvate-flavodoxin oxidoreductase activity
CGC46_RS06310	COG1013	pyruvate-flavodoxin oxidoreductase activity
CGC46_RS06310	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CGC46_RS06310	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGC46_RS06315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CGC46_RS06320	COG0589	response to stress
CGC46_RS06340	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS06420	COG0740	serine-type endopeptidase activity
CGC46_RS06460	COG3772	lysozyme
CGC46_RS06560	COG1846	Transcriptional regulator
CGC46_RS06565	COG1484	DNA-dependent DNA replication
CGC46_RS06570	COG3756	Protein conserved in bacteria
CGC46_RS06610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CGC46_RS06615	COG3723	Recombinational DNA repair protein, rece pathway
CGC46_RS06635	COG0582	viral genome integration into host DNA
CGC46_RS06645	COG0513	Belongs to the DEAD box helicase family
CGC46_RS06660	COG3706	GGDEF domain
CGC46_RS06665	COG2840	Smr protein MutS2
CGC46_RS06675	COG0583	DNA-binding transcription factor activity
CGC46_RS06680	COG1473	amidohydrolase
CGC46_RS06685	COG1473	amidohydrolase
CGC46_RS06695	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CGC46_RS06700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGC46_RS06705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGC46_RS06710	COG0589	response to stress
CGC46_RS06715	COG3182	Iron-regulated membrane protein
CGC46_RS06720	COG0668	transmembrane transport
CGC46_RS06725	COG4166	transmembrane transport
CGC46_RS06730	COG0583	DNA-binding transcription factor activity
CGC46_RS06735	COG1073	alpha beta
CGC46_RS06740	COG1073	alpha beta
CGC46_RS06745	COG0702	epimerase
CGC46_RS06750	COG2866	Carboxypeptidase
CGC46_RS06755	COG4948	Mandelate Racemase Muconate Lactonizing
CGC46_RS06760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CGC46_RS06765	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CGC46_RS06775	COG3106	COG3106 Predicted ATPase
CGC46_RS06780	COG1609	Transcriptional regulator
CGC46_RS06790	COG3842	ATPase activity
CGC46_RS06795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGC46_RS06800	COG1554	hydrolase, family 65, central catalytic
CGC46_RS06805	COG0673	inositol 2-dehydrogenase activity
CGC46_RS06810	COG1082	Xylose isomerase domain protein TIM barrel
CGC46_RS06815	COG1063	alcohol dehydrogenase
CGC46_RS06820	COG0395	ABC-type sugar transport system, permease component
CGC46_RS06825	COG1175	transmembrane transport
CGC46_RS06835	COG0366	Alpha amylase catalytic
CGC46_RS06840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGC46_RS06850	COG1983	PspC domain protein
CGC46_RS06860	COG1842	Phage shock protein A
CGC46_RS06865	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CGC46_RS06870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGC46_RS06875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGC46_RS06880	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS06890	COG1917	Cupin 2, conserved barrel domain protein
CGC46_RS06890	COG1396	sequence-specific DNA binding
CGC46_RS06895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CGC46_RS06900	COG0174	glutamine synthetase
CGC46_RS06905	COG0531	amino acid
CGC46_RS06920	COG4166	transmembrane transport
CGC46_RS06925	COG4168	peptide transport system, permease
CGC46_RS06930	COG4171	peptide transport system, permease
CGC46_RS06935	COG4172	Belongs to the ABC transporter superfamily
CGC46_RS06940	COG4172	Belongs to the ABC transporter superfamily
CGC46_RS06945	COG2852	Protein conserved in bacteria
CGC46_RS06950	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CGC46_RS06955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGC46_RS06955	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGC46_RS06970	COG5001	Diguanylate cyclase
CGC46_RS06980	COG1349	DNA-binding transcription factor activity
CGC46_RS06990	COG0023	Translation Initiation Factor
CGC46_RS07000	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CGC46_RS07005	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CGC46_RS07010	COG0671	phosphoesterase, PA-phosphatase related
CGC46_RS07020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CGC46_RS07040	COG0583	DNA-binding transcription factor activity
CGC46_RS07050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGC46_RS07065	COG0616	signal peptide processing
CGC46_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS07075	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CGC46_RS07080	COG1187	pseudouridine synthase activity
CGC46_RS07085	COG0009	L-threonylcarbamoyladenylate synthase
CGC46_RS07090	COG0613	PHP domain protein
CGC46_RS07100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CGC46_RS07105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CGC46_RS07105	COG0512	Glutamine amidotransferase of anthranilate synthase
CGC46_RS07110	COG0134	indole-3-glycerol-phosphate synthase activity
CGC46_RS07110	COG0135	phosphoribosylanthranilate isomerase activity
CGC46_RS07125	COG3729	General stress protein
CGC46_RS07130	COG3685	Protein conserved in bacteria
CGC46_RS07135	COG3685	Protein conserved in bacteria
CGC46_RS07245	COG1403	HNH endonuclease
CGC46_RS07280	COG1846	Transcriptional regulator
CGC46_RS07300	COG1396	sequence-specific DNA binding
CGC46_RS07345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CGC46_RS07360	COG3047	cAMP biosynthetic process
CGC46_RS07375	COG1607	acyl-coa hydrolase
CGC46_RS07380	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CGC46_RS07385	COG2350	Protein conserved in bacteria
CGC46_RS07390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGC46_RS07410	COG4608	Belongs to the ABC transporter superfamily
CGC46_RS07415	COG0444	Belongs to the ABC transporter superfamily
CGC46_RS07420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGC46_RS07425	COG0601	transmembrane transport
CGC46_RS07430	COG4166	transmembrane transport
CGC46_RS07440	COG2095	MarC family integral membrane protein
CGC46_RS07445	COG1454	alcohol dehydrogenase
CGC46_RS07445	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS07450	COG1435	thymidine kinase activity
CGC46_RS07460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGC46_RS07465	COG0745	RESPONSE REGULATOR receiver
CGC46_RS07470	COG1752	Esterase of the alpha-beta hydrolase superfamily
CGC46_RS07480	COG0788	formyltetrahydrofolate deformylase activity
CGC46_RS07500	COG2181	nitrate reductase activity
CGC46_RS07505	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CGC46_RS07510	COG1140	nitrate reductase beta subunit
CGC46_RS07515	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CGC46_RS07520	COG2223	nitrite transmembrane transporter activity
CGC46_RS07530	COG3850	Histidine kinase
CGC46_RS07535	COG2197	response regulator
CGC46_RS07540	COG4932	domain protein
CGC46_RS07545	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CGC46_RS07550	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CGC46_RS07555	COG4572	Cation transport regulator
CGC46_RS07560	COG0387	Pfam Sodium calcium exchanger
CGC46_RS07585	COG2912	Transglutaminase-like superfamily
CGC46_RS07590	COG3094	Invasion gene expression up-regulator, SirB
CGC46_RS07595	COG2890	protein-(glutamine-N5) methyltransferase activity
CGC46_RS07625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CGC46_RS07635	COG0659	secondary active sulfate transmembrane transporter activity
CGC46_RS07650	COG0012	GTP binding
CGC46_RS07665	COG3468	outer membrane autotransporter barrel domain protein
CGC46_RS07670	COG3284	Transcriptional regulator
CGC46_RS07675	COG2376	Dihydroxyacetone kinase
CGC46_RS07680	COG1461	Dihydroxyacetone kinase
CGC46_RS07685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS07685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGC46_RS07685	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CGC46_RS07710	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CGC46_RS07725	COG1619	proteins homologs of microcin C7 resistance protein MccF
CGC46_RS07735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGC46_RS07745	COG2719	SpoVR family
CGC46_RS07765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGC46_RS07770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CGC46_RS07785	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGC46_RS07815	COG2894	cell division
CGC46_RS07875	COG2200	EAL domain
CGC46_RS07900	COG2200	EAL domain
CGC46_RS07905	COG0789	Transcriptional regulator
CGC46_RS07910	COG5562	phage envelope protein
CGC46_RS07920	COG0538	isocitrate dehydrogenase activity
CGC46_RS07925	COG1187	pseudouridine synthase activity
CGC46_RS07945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGC46_RS07955	COG2205	protein histidine kinase activity
CGC46_RS07960	COG2850	peptidyl-arginine hydroxylation
CGC46_RS07975	COG3842	ATPase activity
CGC46_RS08025	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS08145	COG4220	transposase activity
CGC46_RS08170	COG3772	lysozyme
CGC46_RS08185	COG4372	Transposase
CGC46_RS08190	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS08235	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CGC46_RS08400	COG0582	viral genome integration into host DNA
CGC46_RS08405	COG0784	Response regulator, receiver
CGC46_RS08405	COG2198	Histidine kinase
CGC46_RS08405	COG2205	protein histidine kinase activity
CGC46_RS08410	COG0348	domain, Protein
CGC46_RS08430	COG1278	Cold shock
CGC46_RS08435	COG1278	Cold shock
CGC46_RS08455	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CGC46_RS08460	COG1596	polysaccharide export
CGC46_RS08465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGC46_RS08470	COG0489	protein tyrosine kinase activity
CGC46_RS08470	COG3206	protein involved in exopolysaccharide biosynthesis
CGC46_RS08485	COG1294	oxidase, subunit
CGC46_RS08490	COG1271	oxidase subunit
CGC46_RS08495	COG1773	rubredoxin
CGC46_RS08500	COG1999	signal sequence binding
CGC46_RS08505	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CGC46_RS08510	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CGC46_RS08515	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CGC46_RS08550	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS08730	COG3772	lysozyme
CGC46_RS08745	COG3772	lysozyme
CGC46_RS08830	COG0484	heat shock protein binding
CGC46_RS08835	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CGC46_RS08840	COG1403	HNH endonuclease
CGC46_RS08850	COG3111	PFAM Bacterial OB fold (BOF) protein
CGC46_RS08885	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS08890	COG4372	Transposase
CGC46_RS08910	COG1846	Transcriptional regulator
CGC46_RS08960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CGC46_RS08970	COG0582	viral genome integration into host DNA
CGC46_RS08985	COG1177	transmembrane transport
CGC46_RS08990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CGC46_RS08995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CGC46_RS09005	COG4591	ABC-type transport system involved in lipoprotein release permease component
CGC46_RS09015	COG4591	ABC-type transport system involved in lipoprotein release permease component
CGC46_RS09020	COG4763	Acyl-transferase
CGC46_RS09025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CGC46_RS09030	COG1376	ErfK ybiS ycfS ynhG family protein
CGC46_RS09030	COG1388	LysM domain
CGC46_RS09040	COG1309	transcriptional regulator
CGC46_RS09045	COG3134	Outer membrane lipoprotein
CGC46_RS09055	COG1252	NADH dehydrogenase
CGC46_RS09075	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CGC46_RS09080	COG5633	Lipoprotein
CGC46_RS09085	COG0537	adenosine 5'-monophosphoramidase activity
CGC46_RS09090	COG4773	Receptor
CGC46_RS09095	COG1263	PTS System
CGC46_RS09095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS09100	COG0084	hydrolase, TatD family'
CGC46_RS09105	COG0470	DNA polymerase III
CGC46_RS09115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CGC46_RS09120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGC46_RS09125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGC46_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS09140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CGC46_RS09160	COG1399	metal-binding, possibly nucleic acid-binding protein
CGC46_RS09165	COG0424	maF-like protein
CGC46_RS09170	COG0564	pseudouridine synthase activity
CGC46_RS09180	COG1530	ribonuclease E activity
CGC46_RS09185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CGC46_RS09190	COG1256	bacterial-type flagellum assembly
CGC46_RS09195	COG1705	Flagellar rod assembly protein muramidase FlgJ
CGC46_RS09195	COG3951	Flagellar rod assembly protein muramidase FlgJ
CGC46_RS09210	COG4786	Flagellar basal body rod
CGC46_RS09215	COG4787	bacterial-type flagellum-dependent cell motility
CGC46_RS09220	COG1749	Flagellar hook protein flgE
CGC46_RS09225	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CGC46_RS09230	COG1558	bacterial-type flagellum-dependent cell motility
CGC46_RS09235	COG1815	bacterial-type flagellum-dependent cell motility
CGC46_RS09240	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CGC46_RS09245	COG2747	anti-sigma28 factor FlgM
CGC46_RS09250	COG3418	PFAM FlgN family protein
CGC46_RS09255	COG0728	peptidoglycan biosynthetic process
CGC46_RS09260	COG0673	inositol 2-dehydrogenase activity
CGC46_RS09270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGC46_RS09280	COG2999	glutathione oxidoreductase activity
CGC46_RS09320	COG3038	cytochrome b561
CGC46_RS09325	COG2353	YceI-like domain
CGC46_RS09335	COG1560	Kdo2-lipid A biosynthetic process
CGC46_RS09350	COG5645	(Lipo)protein
CGC46_RS09355	COG2943	transferase activity, transferring hexosyl groups
CGC46_RS09380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGC46_RS09385	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CGC46_RS09420	COG2197	response regulator
CGC46_RS09435	COG1462	curli production assembly transport component CsgG
CGC46_RS09445	COG3381	protein complex oligomerization
CGC46_RS09475	COG1702	phosphate starvation-inducible protein PhoH
CGC46_RS09485	COG2822	iron ion transport
CGC46_RS09505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGC46_RS09520	COG0506	proline dehydrogenase activity
CGC46_RS09520	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CGC46_RS09520	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CGC46_RS09525	COG1309	transcriptional regulator
CGC46_RS09560	COG2233	PERMEase
CGC46_RS09565	COG3729	General stress protein
CGC46_RS09610	COG0243	molybdopterin cofactor binding
CGC46_RS09615	COG3005	denitrification pathway
CGC46_RS09620	COG0745	RESPONSE REGULATOR receiver
CGC46_RS09625	COG1879	ABC-type sugar transport system periplasmic component
CGC46_RS09665	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS09770	COG4220	transposase activity
CGC46_RS09800	COG3772	lysozyme
CGC46_RS09860	COG2207	Transcriptional regulator
CGC46_RS09880	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CGC46_RS09885	COG1403	HNH endonuclease
CGC46_RS09910	COG1846	Transcriptional regulator
CGC46_RS09915	COG1484	DNA-dependent DNA replication
CGC46_RS09990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CGC46_RS10165	COG3772	lysozyme
CGC46_RS10210	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CGC46_RS10215	COG1403	HNH endonuclease
CGC46_RS10290	COG4197	protein conserved in bacteria, prophage-related
CGC46_RS10355	COG0670	Belongs to the BI1 family
CGC46_RS10360	COG2920	part of a sulfur-relay system
CGC46_RS10365	COG1254	Belongs to the acylphosphatase family
CGC46_RS10380	COG1832	CoA-binding protein
CGC46_RS10395	COG0210	DNA helicase
CGC46_RS10400	COG3304	Inner membrane component domain
CGC46_RS10405	COG1289	transmembrane transporter activity
CGC46_RS10410	COG3070	regulator of competence-specific genes
CGC46_RS10435	COG1067	ATP-dependent peptidase activity
CGC46_RS10445	COG3130	regulation of translation
CGC46_RS10450	COG3009	Protein conserved in bacteria
CGC46_RS10455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CGC46_RS10455	COG3008	intermembrane lipid transfer
CGC46_RS10460	COG2995	paraquat-inducible protein a
CGC46_RS10465	COG0488	(ABC) transporter
CGC46_RS10475	COG0633	Ferredoxin
CGC46_RS10475	COG3217	Mosc domain protein beta barrel domain protein
CGC46_RS10490	COG3121	Chaperone
CGC46_RS10495	COG3539	Fimbrial protein
CGC46_RS10500	COG3539	Fimbrial protein
CGC46_RS10505	COG3539	Fimbrial protein
CGC46_RS10520	COG3539	Fimbrial protein
CGC46_RS10525	COG0431	NADPH-dependent FMN reductase
CGC46_RS10530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CGC46_RS10540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGC46_RS10550	COG0308	aminopeptidase N
CGC46_RS10575	COG1448	Aminotransferase
CGC46_RS10580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGC46_RS10585	COG3108	Peptidase M15
CGC46_RS10595	COG2989	Protein conserved in bacteria
CGC46_RS10605	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CGC46_RS10615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CGC46_RS10620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CGC46_RS10625	COG3173	Aminoglycoside phosphotransferase
CGC46_RS10640	COG3214	Protein conserved in bacteria
CGC46_RS10650	COG1132	(ABC) transporter
CGC46_RS10655	COG2333	competence protein COMEC
CGC46_RS10655	COG0658	competence protein
CGC46_RS10665	COG0539	negative regulation of cytoplasmic translation
CGC46_RS10675	COG0501	Belongs to the peptidase M48B family
CGC46_RS10690	COG2323	membrane
CGC46_RS10695	COG1944	ATP diphosphatase activity
CGC46_RS10700	COG2116	formate transmembrane transporter activity
CGC46_RS10705	COG1882	Formate acetyltransferase
CGC46_RS10710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CGC46_RS10715	COG2249	NAD(P)H dehydrogenase (quinone) activity
CGC46_RS10720	COG0583	DNA-binding transcription factor activity
CGC46_RS10725	COG0531	amino acid
CGC46_RS10735	COG1335	isochorismatase
CGC46_RS10740	COG3302	dmso reductase anchor subunit
CGC46_RS10745	COG0437	4 iron, 4 sulfur cluster binding
CGC46_RS10750	COG0243	molybdopterin cofactor binding
CGC46_RS10760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CGC46_RS10770	COG1674	ftsk spoiiie
CGC46_RS10770	COG1178	ABC-type Fe3 transport system permease component
CGC46_RS10775	COG1522	sequence-specific DNA binding
CGC46_RS10785	COG0492	ferredoxin-NADP+ reductase activity
CGC46_RS10790	COG4988	ABC transporter
CGC46_RS10795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CGC46_RS10820	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS10825	COG4372	Transposase
CGC46_RS10830	COG0542	response to heat
CGC46_RS10840	COG1278	Cold shock
CGC46_RS10850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC46_RS10855	COG2990	Protein conserved in bacteria
CGC46_RS10860	COG3593	DNA synthesis involved in DNA repair
CGC46_RS10875	COG2431	L-lysine efflux transmembrane transporter activity
CGC46_RS10885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGC46_RS10890	COG0028	Belongs to the TPP enzyme family
CGC46_RS10895	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CGC46_RS10900	COG0702	epimerase
CGC46_RS10905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGC46_RS10910	COG3023	N-Acetylmuramoyl-L-alanine amidase
CGC46_RS10925	COG1126	abc transporter atp-binding protein
CGC46_RS10930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC46_RS10935	COG4215	(ABC) transporter
CGC46_RS10940	COG4160	amino acid transport
CGC46_RS10945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC46_RS10960	COG1177	transmembrane transport
CGC46_RS10965	COG1176	ABC-type spermidine putrescine transport system, permease component I
CGC46_RS10970	COG3842	ATPase activity
CGC46_RS10975	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CGC46_RS10995	COG0778	Nitroreductase
CGC46_RS11005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CGC46_RS11020	COG3226	Transcriptional regulator
CGC46_RS11025	COG0738	Major facilitator superfamily
CGC46_RS11030	COG0561	phosphatase activity
CGC46_RS11040	COG2814	Major facilitator Superfamily
CGC46_RS11045	COG0671	phosphoesterase, PA-phosphatase related
CGC46_RS11050	COG1349	DNA-binding transcription factor activity
CGC46_RS11055	COG1686	Belongs to the peptidase S11 family
CGC46_RS11065	COG2133	pyrroloquinoline quinone binding
CGC46_RS11080	COG2199	diguanylate cyclase activity
CGC46_RS11085	COG2200	EAL domain
CGC46_RS11110	COG1446	asparaginase
CGC46_RS11115	COG0303	'Molybdopterin
CGC46_RS11120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CGC46_RS11125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGC46_RS11130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CGC46_RS11135	COG1882	Formate acetyltransferase
CGC46_RS11140	COG0561	phosphatase activity
CGC46_RS11150	COG0488	(ABC) transporter
CGC46_RS11155	COG1376	ErfK ybiS ycfS ynhG family protein
CGC46_RS11160	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CGC46_RS11165	COG1321	iron dependent repressor
CGC46_RS11175	COG2194	sulfuric ester hydrolase activity
CGC46_RS11180	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CGC46_RS11185	COG5006	permease, DMT superfamily
CGC46_RS11210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC46_RS11215	COG0765	amino acid transport
CGC46_RS11220	COG1126	abc transporter atp-binding protein
CGC46_RS11225	COG0668	transmembrane transport
CGC46_RS11240	COG4774	siderophore transport
CGC46_RS11250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CGC46_RS11260	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CGC46_RS11265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CGC46_RS11270	COG1199	ATP-dependent helicase activity
CGC46_RS11280	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CGC46_RS11285	COG0513	Belongs to the DEAD box helicase family
CGC46_RS11290	COG1309	transcriptional regulator
CGC46_RS11300	COG1131	(ABC) transporter
CGC46_RS11305	COG0842	Transport permease protein
CGC46_RS11310	COG0842	Transport permease protein
CGC46_RS11320	COG3568	Endonuclease Exonuclease Phosphatase
CGC46_RS11325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGC46_RS11330	COG0392	lysyltransferase activity
CGC46_RS11335	COG0670	Belongs to the BI1 family
CGC46_RS11345	COG0670	Belongs to the BI1 family
CGC46_RS11350	COG0314	molybdopterin synthase activity
CGC46_RS11355	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CGC46_RS11365	COG0521	Mo-molybdopterin cofactor biosynthetic process
CGC46_RS11375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CGC46_RS11385	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CGC46_RS11390	COG2226	methyltransferase
CGC46_RS11405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CGC46_RS11410	COG1881	PFAM PEBP family protein
CGC46_RS11420	COG4677	pectinesterase activity
CGC46_RS11425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CGC46_RS11430	COG0471	metal ion transport
CGC46_RS11435	COG2828	Protein conserved in bacteria
CGC46_RS11440	COG0583	DNA-binding transcription factor activity
CGC46_RS11450	COG0561	phosphatase activity
CGC46_RS11460	COG4149	molybdate abc transporter
CGC46_RS11465	COG0725	ABC transporter, periplasmic molybdate-binding protein
CGC46_RS11480	COG3585	molybdate ion transport
CGC46_RS11480	COG2005	Transcriptional regulator
CGC46_RS11485	COG1119	ATPase activity
CGC46_RS11490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CGC46_RS11495	COG1085	galactose-1-phosphate uridylyltransferase
CGC46_RS11505	COG2017	converts alpha-aldose to the beta-anomer
CGC46_RS11515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CGC46_RS11530	COG1230	cation diffusion facilitator family transporter
CGC46_RS11535	COG3201	nicotinamide mononucleotide transporter
CGC46_RS11580	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CGC46_RS11585	COG2885	chlorophyll binding
CGC46_RS11595	COG3064	Membrane
CGC46_RS11600	COG0848	biopolymer transport protein
CGC46_RS11605	COG0811	peptide transport
CGC46_RS11610	COG0824	Thioesterase
CGC46_RS11615	COG3790	cyd operon protein YbgE
CGC46_RS11620	COG4890	Cyd operon protein YbgT
CGC46_RS11625	COG1294	oxidase, subunit
CGC46_RS11630	COG1271	oxidase subunit
CGC46_RS11640	COG0383	alpha-mannosidase activity
CGC46_RS11645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS11645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS11645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS11650	COG2188	Transcriptional regulator
CGC46_RS11655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CGC46_RS11665	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGC46_RS11670	COG0567	Dehydrogenase, E1 component
CGC46_RS11675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CGC46_RS11680	COG1053	succinate dehydrogenase
CGC46_RS11685	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CGC46_RS11690	COG2009	succinate dehydrogenase
CGC46_RS11705	COG0372	Belongs to the citrate synthase family
CGC46_RS11710	COG3539	Fimbrial protein
CGC46_RS11715	COG3188	usher protein
CGC46_RS11720	COG3121	Chaperone
CGC46_RS11725	COG3539	Fimbrial protein
CGC46_RS11730	COG3180	Ammonia monooxygenase
CGC46_RS11745	COG1984	allophanate hydrolase subunit 2
CGC46_RS11750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CGC46_RS11755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CGC46_RS11765	COG0415	Belongs to the DNA photolyase family
CGC46_RS11770	COG3272	Protein of unknown function (DUF1722)
CGC46_RS11855	COG2205	protein histidine kinase activity
CGC46_RS11860	COG0745	RESPONSE REGULATOR receiver
CGC46_RS11870	COG1982	Orn Lys Arg decarboxylase major
CGC46_RS11875	COG0531	amino acid
CGC46_RS11880	COG0033	Phosphoglucomutase
CGC46_RS11885	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CGC46_RS11890	COG0596	Alpha beta hydrolase
CGC46_RS11900	COG0716	FMN binding
CGC46_RS11910	COG0735	belongs to the Fur family
CGC46_RS11930	COG2190	(PTS) system
CGC46_RS11930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS11930	COG1263	PTS System
CGC46_RS11940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CGC46_RS11945	COG1940	carbohydrate kinase activity
CGC46_RS11945	COG1846	Transcriptional regulator
CGC46_RS11950	COG0647	UMP catabolic process
CGC46_RS11960	COG0367	asparagine synthase
CGC46_RS12005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGC46_RS12015	COG1702	phosphate starvation-inducible protein PhoH
CGC46_RS12025	COG4535	Mg2 and Co2 transporter CorC
CGC46_RS12030	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CGC46_RS12045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC46_RS12050	COG0765	amino acid transport
CGC46_RS12055	COG0765	amino acid transport
CGC46_RS12060	COG1126	abc transporter atp-binding protein
CGC46_RS12070	COG0443	Heat shock 70 kDa protein
CGC46_RS12075	COG2214	Heat shock protein DnaJ domain protein
CGC46_RS12085	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CGC46_RS12090	COG2214	Heat shock protein DnaJ domain protein
CGC46_RS12100	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CGC46_RS12105	COG2888	peptidyl-tyrosine sulfation
CGC46_RS12120	COG1466	dna polymerase III delta subunit
CGC46_RS12130	COG0406	alpha-ribazole phosphatase activity
CGC46_RS12135	COG0799	negative regulation of ribosome biogenesis
CGC46_RS12145	COG0768	penicillin binding
CGC46_RS12150	COG0772	Belongs to the SEDS family
CGC46_RS12155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CGC46_RS12160	COG1686	Belongs to the peptidase S11 family
CGC46_RS12180	COG0583	DNA-binding transcription factor activity
CGC46_RS12195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGC46_RS12200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGC46_RS12225	COG3069	C4-dicarboxylate transmembrane transporter activity
CGC46_RS12230	COG4565	transcriptional regulatory protein
CGC46_RS12235	COG3290	protein histidine kinase activity
CGC46_RS12240	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CGC46_RS12250	COG2301	Belongs to the HpcH HpaI aldolase family
CGC46_RS12255	COG3051	citrate lyase alpha subunit
CGC46_RS12270	COG0471	metal ion transport
CGC46_RS12275	COG3719	Belongs to the RNase T2 family
CGC46_RS12285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CGC46_RS12295	COG1063	alcohol dehydrogenase
CGC46_RS12300	COG0589	response to stress
CGC46_RS12305	COG3634	alkyl hydroperoxide reductase activity
CGC46_RS12310	COG0450	alkyl hydroperoxide reductase
CGC46_RS12315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CGC46_RS12320	COG0583	DNA-binding transcription factor activity
CGC46_RS12325	COG3969	phosphoadenosine phosphosulfate
CGC46_RS12330	COG1475	DNA binding
CGC46_RS12335	COG0436	Aminotransferase
CGC46_RS12340	COG0371	Dehydrogenase
CGC46_RS12345	COG2879	small protein
CGC46_RS12350	COG1966	Carbon starvation protein
CGC46_RS12355	COG2050	protein possibly involved in aromatic compounds catabolism
CGC46_RS12360	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS12365	COG3433	isochorismatase activity
CGC46_RS12365	COG1535	isochorismatase
CGC46_RS12370	COG1021	2,3-dihydroxybenzoate-AMP ligase
CGC46_RS12375	COG1169	isochorismate synthase
CGC46_RS12385	COG4592	Periplasmic binding protein
CGC46_RS12395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGC46_RS12400	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGC46_RS12405	COG1120	ATPase activity
CGC46_RS12410	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CGC46_RS12415	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CGC46_RS12415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CGC46_RS12420	COG3251	PFAM MbtH domain protein
CGC46_RS12425	COG2382	esterase
CGC46_RS12435	COG4771	TonB-dependent receptor
CGC46_RS12440	COG2977	Belongs to the P-Pant transferase superfamily
CGC46_RS12475	COG2315	Protein conserved in bacteria
CGC46_RS12480	COG0778	Nitroreductase
CGC46_RS12485	COG0668	transmembrane transport
CGC46_RS12490	COG1113	amino acid transport
CGC46_RS12495	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGC46_RS12500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC46_RS12505	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC46_RS12510	COG1538	Outer membrane efflux protein
CGC46_RS12520	COG0745	RESPONSE REGULATOR receiver
CGC46_RS12525	COG5002	protein histidine kinase activity
CGC46_RS12530	COG3501	Rhs element vgr protein
CGC46_RS12540	COG3209	COG3209 Rhs family protein
CGC46_RS12540	COG4104	PAAR repeat-containing protein
CGC46_RS12590	COG5433	transposase activity
CGC46_RS12595	COG1215	transferase activity, transferring glycosyl groups
CGC46_RS12600	COG4783	chaperone-mediated protein folding
CGC46_RS12615	COG2207	Transcriptional regulator
CGC46_RS12630	COG4571	Outer membrane protease
CGC46_RS12645	COG0500	methyltransferase
CGC46_RS12655	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CGC46_RS12660	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS12710	COG1196	nuclear chromosome segregation
CGC46_RS12760	COG1030	water channel activity
CGC46_RS12780	COG4220	transposase activity
CGC46_RS12810	COG0582	viral genome integration into host DNA
CGC46_RS12820	COG2197	response regulator
CGC46_RS12825	COG3539	Fimbrial protein
CGC46_RS12830	COG3539	Fimbrial protein
CGC46_RS12835	COG3188	usher protein
CGC46_RS12845	COG3539	Fimbrial protein
CGC46_RS12855	COG2501	S4 domain
CGC46_RS12860	COG1988	membrane-bound metal-dependent
CGC46_RS12870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CGC46_RS12885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CGC46_RS12890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CGC46_RS12895	COG0549	Belongs to the carbamate kinase family
CGC46_RS12905	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CGC46_RS12910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CGC46_RS12915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CGC46_RS12920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGC46_RS12925	COG3257	ureidoglycine aminohydrolase activity
CGC46_RS12930	COG1929	Belongs to the glycerate kinase type-1 family
CGC46_RS12935	COG2233	PERMEase
CGC46_RS12945	COG1953	Uracil, thiamine, allantoin
CGC46_RS12950	COG2084	Dehydrogenase
CGC46_RS12955	COG3622	Belongs to the hyi family
CGC46_RS12960	COG3960	tartronate-semialdehyde synthase activity
CGC46_RS12965	COG1414	Transcriptional regulator
CGC46_RS12975	COG0583	DNA-binding transcription factor activity
CGC46_RS13000	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CGC46_RS13005	COG4181	ATPase activity
CGC46_RS13010	COG2755	lipolytic protein G-D-S-L family
CGC46_RS13015	COG0300	oxidoreductase activity
CGC46_RS13020	COG3118	belongs to the thioredoxin family
CGC46_RS13025	COG0390	transport system, permease component
CGC46_RS13030	COG4619	ABC transporter
CGC46_RS13035	COG0330	HflC and HflK could
CGC46_RS13040	COG1585	Membrane protein implicated in regulation of membrane protease activity
CGC46_RS13045	COG0789	Transcriptional regulator
CGC46_RS13050	COG0531	amino acid
CGC46_RS13060	COG2217	Heavy metal translocating P-type atpase
CGC46_RS13065	COG3093	addiction module antidote protein HigA
CGC46_RS13075	COG3735	TraB family
CGC46_RS13085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGC46_RS13090	COG0737	Belongs to the 5'-nucleotidase family
CGC46_RS13100	COG2223	nitrite transmembrane transporter activity
CGC46_RS13105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGC46_RS13105	COG4651	solute:proton antiporter activity
CGC46_RS13110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC46_RS13150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGC46_RS13165	COG2832	Protein of unknown function (DUF454)
CGC46_RS13170	COG3923	Primosomal replication protein n
CGC46_RS13180	COG3264	Mechanosensitive ion channel
CGC46_RS13180	COG1196	nuclear chromosome segregation
CGC46_RS13190	COG1309	transcriptional regulator
CGC46_RS13195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC46_RS13200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGC46_RS13215	COG0110	maltose O-acetyltransferase activity
CGC46_RS13225	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CGC46_RS13230	COG5507	3-demethylubiquinone-9 3-methyltransferase
CGC46_RS13240	COG3695	enzyme binding
CGC46_RS13245	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CGC46_RS13250	COG1946	Acyl-CoA thioesterase
CGC46_RS13255	COG0004	ammonium transporteR
CGC46_RS13260	COG0347	Belongs to the P(II) protein family
CGC46_RS13265	COG1132	(ABC) transporter
CGC46_RS13270	COG1132	(ABC) transporter
CGC46_RS13275	COG1522	sequence-specific DNA binding
CGC46_RS13285	COG4533	DNA binding
CGC46_RS13295	COG0824	Thioesterase
CGC46_RS13300	COG1555	photosystem II stabilization
CGC46_RS13305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CGC46_RS13310	COG0776	regulation of translation
CGC46_RS13315	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CGC46_RS13340	COG0271	Belongs to the BolA IbaG family
CGC46_RS13345	COG3056	Lipoprotein
CGC46_RS13350	COG2223	nitrite transmembrane transporter activity
CGC46_RS13355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CGC46_RS13360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGC46_RS13365	COG1845	cytochrome c oxidase, subunit III
CGC46_RS13370	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CGC46_RS13395	COG2814	Major facilitator Superfamily
CGC46_RS13405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CGC46_RS13410	COG0693	protein deglycase activity
CGC46_RS13425	COG0142	geranyltranstransferase activity
CGC46_RS13435	COG0667	Aldo Keto reductase
CGC46_RS13440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CGC46_RS13445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CGC46_RS13460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CGC46_RS13460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CGC46_RS13470	COG4238	major outer membrane lipoprotein
CGC46_RS13475	COG3248	Nucleoside-binding outer membrane protein
CGC46_RS13480	COG1403	HNH endonuclease
CGC46_RS13485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGC46_RS13490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGC46_RS13495	COG1862	Preprotein translocase
CGC46_RS13515	COG0366	Alpha amylase catalytic
CGC46_RS13520	COG1113	amino acid transport
CGC46_RS13525	COG1114	Component of the transport system for branched-chain amino acids
CGC46_RS13530	COG5002	protein histidine kinase activity
CGC46_RS13535	COG0745	RESPONSE REGULATOR receiver
CGC46_RS13540	COG0420	3'-5' exonuclease activity
CGC46_RS13545	COG0419	ATPase involved in DNA repair
CGC46_RS13550	COG2814	Major facilitator Superfamily
CGC46_RS13580	COG4126	flavin adenine dinucleotide binding
CGC46_RS13605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGC46_RS13610	COG3706	GGDEF domain
CGC46_RS13620	COG1785	Belongs to the alkaline phosphatase family
CGC46_RS13635	COG1181	Belongs to the D-alanine--D-alanine ligase family
CGC46_RS13660	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CGC46_RS13670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CGC46_RS13675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGC46_RS13680	COG3468	outer membrane autotransporter barrel domain protein
CGC46_RS13690	COG0113	porphobilinogen synthase activity
CGC46_RS13695	COG2175	clavaminate synthase activity
CGC46_RS13700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGC46_RS13710	COG4521	taurine ABC transporter
CGC46_RS13720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGC46_RS13725	COG1215	transferase activity, transferring glycosyl groups
CGC46_RS13755	COG3122	Protein conserved in bacteria
CGC46_RS13760	COG2814	Major facilitator Superfamily
CGC46_RS13795	COG1414	Transcriptional regulator
CGC46_RS13800	COG1609	Transcriptional regulator
CGC46_RS13820	COG2223	nitrite transmembrane transporter activity
CGC46_RS13825	COG0110	maltose O-acetyltransferase activity
CGC46_RS13830	COG2807	transmembrane transport
CGC46_RS13840	COG0288	reversible hydration of carbon dioxide
CGC46_RS13845	COG0583	DNA-binding transcription factor activity
CGC46_RS13850	COG0402	S-adenosylhomocysteine deaminase activity
CGC46_RS13855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CGC46_RS13860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CGC46_RS13865	COG2079	MmgE PrpD family protein
CGC46_RS13870	COG0372	Belongs to the citrate synthase family
CGC46_RS13875	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CGC46_RS13880	COG3829	transcription factor binding
CGC46_RS13890	COG1280	lysine exporter protein (LysE YggA)
CGC46_RS13905	COG1064	alcohol dehydrogenase
CGC46_RS13915	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGC46_RS13920	COG1129	ABC transporter
CGC46_RS13925	COG1879	ABC-type sugar transport system periplasmic component
CGC46_RS13935	COG0402	S-adenosylhomocysteine deaminase activity
CGC46_RS13940	COG0549	Belongs to the carbamate kinase family
CGC46_RS13945	COG1304	FMN binding
CGC46_RS13950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CGC46_RS13960	COG0666	response to abiotic stimulus
CGC46_RS13975	COG0583	DNA-binding transcription factor activity
CGC46_RS13980	COG2771	luxR family
CGC46_RS13980	COG2200	EAL domain
CGC46_RS13990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CGC46_RS14030	COG1556	Lactate utilization protein
CGC46_RS14035	COG1139	Iron-sulfur cluster binding protein
CGC46_RS14040	COG0247	lactate metabolic process
CGC46_RS14045	COG2207	Transcriptional regulator
CGC46_RS14050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGC46_RS14060	COG3059	membrane
CGC46_RS14065	COG0656	L-ascorbic acid biosynthetic process
CGC46_RS14070	COG2207	Transcriptional regulator
CGC46_RS14070	COG3708	Transcriptional regulator
CGC46_RS14075	COG1388	LysM domain
CGC46_RS14130	COG3188	usher protein
CGC46_RS14140	COG3121	Chaperone
CGC46_RS14145	COG0727	PFAM Uncharacterised protein family (UPF0153)
CGC46_RS14160	COG2080	2 iron, 2 sulfur cluster binding
CGC46_RS14165	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CGC46_RS14170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CGC46_RS14175	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CGC46_RS14180	COG0583	DNA-binding transcription factor activity
CGC46_RS14200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CGC46_RS14220	COG2195	Cleaves the N-terminal amino acid of tripeptides
CGC46_RS14225	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CGC46_RS14230	COG1690	Belongs to the RtcB family
CGC46_RS14240	COG0454	-acetyltransferase
CGC46_RS14270	COG0791	NLP P60 protein
CGC46_RS14275	COG3077	Addiction module antitoxin, RelB DinJ family
CGC46_RS14280	COG3041	Addiction module toxin RelE StbE family
CGC46_RS14285	COG3034	peptidoglycan biosynthetic process
CGC46_RS14290	COG0121	glutamine amidotransferase
CGC46_RS14300	COG1960	acyl-CoA dehydrogenase activity
CGC46_RS14310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGC46_RS14330	COG3209	COG3209 Rhs family protein
CGC46_RS14425	COG3157	Type VI secretion system effector, Hcp
CGC46_RS14455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CGC46_RS14465	COG2226	methyltransferase
CGC46_RS14475	COG1388	LysM domain
CGC46_RS14475	COG0741	lytic transglycosylase activity
CGC46_RS14480	COG2226	methyltransferase
CGC46_RS14490	COG0583	DNA-binding transcription factor activity
CGC46_RS14495	COG0656	L-ascorbic acid biosynthetic process
CGC46_RS14530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CGC46_RS14535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CGC46_RS14540	COG2011	ABC-type metal ion transport system permease component
CGC46_RS14545	COG1464	Belongs to the NlpA lipoprotein family
CGC46_RS14555	COG1720	tRNA m6t6A37 methyltransferase activity
CGC46_RS14570	COG3015	lipoprotein NlpE involved in copper resistance
CGC46_RS14575	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CGC46_RS14580	COG4681	YaeQ
CGC46_RS14590	COG4568	rho-dependent transcription termination
CGC46_RS14600	COG0346	lactoylglutathione lyase activity
CGC46_RS14605	COG1982	Orn Lys Arg decarboxylase major
CGC46_RS14615	COG0587	DNA-directed DNA polymerase activity
CGC46_RS14640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CGC46_RS14645	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CGC46_RS14655	COG0750	zinc metalloprotease
CGC46_RS14660	COG0575	Belongs to the CDS family
CGC46_RS14665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGC46_RS14670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CGC46_RS14705	COG0024	Methionine aminopeptidase
CGC46_RS14725	COG3835	regulator
CGC46_RS14730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGC46_RS14750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGC46_RS14755	COG2860	membrane
CGC46_RS14775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGC46_RS14780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGC46_RS14785	COG1120	ATPase activity
CGC46_RS14795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGC46_RS14805	COG1643	Atp-dependent helicase
CGC46_RS14810	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CGC46_RS14820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CGC46_RS14830	COG0617	tRNA 3'-terminal CCA addition
CGC46_RS14835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CGC46_RS14840	COG3539	Fimbrial protein
CGC46_RS14845	COG3121	Chaperone
CGC46_RS14850	COG3188	usher protein
CGC46_RS14855	COG3539	Fimbrial protein
CGC46_RS14860	COG3539	Fimbrial protein
CGC46_RS14865	COG3539	Fimbrial protein
CGC46_RS14900	COG5464	transposase or invertase
CGC46_RS14920	COG0726	polysaccharide deacetylase
CGC46_RS14925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS14930	COG0842	Transport permease protein
CGC46_RS14935	COG1131	(ABC) transporter
CGC46_RS14940	COG0288	reversible hydration of carbon dioxide
CGC46_RS14945	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CGC46_RS14950	COG4993	Dehydrogenase
CGC46_RS14955	COG2132	Multicopper oxidase
CGC46_RS14980	COG1049	propionate catabolic process, 2-methylcitrate cycle
CGC46_RS14990	COG3064	Membrane
CGC46_RS14995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGC46_RS15000	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGC46_RS15005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CGC46_RS15015	COG2186	Transcriptional regulator
CGC46_RS15020	COG1113	amino acid transport
CGC46_RS15025	COG3725	Membrane protein required for beta-lactamase induction
CGC46_RS15030	COG3023	N-Acetylmuramoyl-L-alanine amidase
CGC46_RS15035	COG0157	Belongs to the NadC ModD family
CGC46_RS15045	COG4969	Belongs to the N-Me-Phe pilin family
CGC46_RS15050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CGC46_RS15055	COG1459	type II secretion system
CGC46_RS15065	COG0237	dephospho-CoA kinase activity
CGC46_RS15080	COG0494	nUDIX hydrolase
CGC46_RS15100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CGC46_RS15105	COG0849	cell division
CGC46_RS15110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CGC46_RS15115	COG1181	Belongs to the D-alanine--D-alanine ligase family
CGC46_RS15130	COG0772	Belongs to the SEDS family
CGC46_RS15145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CGC46_RS15150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGC46_RS15155	COG0768	penicillin binding
CGC46_RS15160	COG3116	cell division
CGC46_RS15185	COG1609	Transcriptional regulator
CGC46_RS15195	COG0440	acetolactate synthase activity
CGC46_RS15200	COG0028	Belongs to the TPP enzyme family
CGC46_RS15205	COG0583	DNA-binding transcription factor activity
CGC46_RS15220	COG0473	3-isopropylmalate dehydrogenase activity
CGC46_RS15235	COG2814	Major facilitator Superfamily
CGC46_RS15250	COG4143	(ABC) transporter
CGC46_RS15255	COG1178	ABC-type Fe3 transport system permease component
CGC46_RS15265	COG0586	Pfam SNARE associated Golgi protein
CGC46_RS15270	COG4977	sequence-specific DNA binding
CGC46_RS15280	COG1069	ribulokinase activity
CGC46_RS15290	COG0235	Class ii aldolase
CGC46_RS15295	COG0417	DNA replication proofreading
CGC46_RS15305	COG0564	pseudouridine synthase activity
CGC46_RS15310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CGC46_RS15315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CGC46_RS15320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CGC46_RS15345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGC46_RS15360	COG2271	Major facilitator Superfamily
CGC46_RS15365	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CGC46_RS15370	COG0644	oxidoreductase
CGC46_RS15425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CGC46_RS15430	COG0505	Belongs to the CarA family
CGC46_RS15455	COG1047	Peptidyl-prolyl cis-trans
CGC46_RS15470	COG0196	riboflavin kinase activity
CGC46_RS15505	COG0583	DNA-binding transcription factor activity
CGC46_RS15520	COG3119	arylsulfatase activity
CGC46_RS15550	COG4735	regulation of single-species biofilm formation
CGC46_RS15555	COG1584	GPR1 FUN34 yaaH family protein
CGC46_RS15560	COG0521	Mo-molybdopterin cofactor biosynthetic process
CGC46_RS15565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGC46_RS15570	COG1115	amino acid carrier protein
CGC46_RS15585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CGC46_RS15595	COG0460	homoserine dehydrogenase
CGC46_RS15595	COG0527	aspartate kinase activity
CGC46_RS15605	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CGC46_RS15620	COG0745	RESPONSE REGULATOR receiver
CGC46_RS15625	COG4452	Inner membrane protein CreD
CGC46_RS15630	COG2205	protein histidine kinase activity
CGC46_RS15635	COG0745	RESPONSE REGULATOR receiver
CGC46_RS15640	COG3045	CreA protein
CGC46_RS15645	COG3708	Transcriptional regulator
CGC46_RS15645	COG2207	Transcriptional regulator
CGC46_RS15665	COG0741	lytic transglycosylase activity
CGC46_RS15675	COG0488	(ABC) transporter
CGC46_RS15680	COG3172	ATPase kinase involved in NAD metabolism
CGC46_RS15680	COG1056	cytidyltransferase-related domain
CGC46_RS15685	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CGC46_RS15690	COG0560	Phosphoserine phosphatase
CGC46_RS15695	COG3726	membrane protein affecting hemolysin expression
CGC46_RS15725	COG1328	CTP reductase activity
CGC46_RS15730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CGC46_RS15735	COG0084	hydrolase, TatD family'
CGC46_RS15740	COG4667	esterase of the alpha-beta hydrolase superfamily
CGC46_RS15750	COG2823	Periplasmic or secreted lipoprotein
CGC46_RS15795	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS15850	COG3772	lysozyme
CGC46_RS15920	COG1403	HNH endonuclease
CGC46_RS15945	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CGC46_RS15955	COG4725	Belongs to the MT-A70-like family
CGC46_RS16020	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CGC46_RS16055	COG1011	Hydrolase
CGC46_RS16060	COG0456	acetyltransferase
CGC46_RS16065	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CGC46_RS16095	COG4114	ferric iron reductase
CGC46_RS16100	COG2197	response regulator
CGC46_RS16105	COG2197	response regulator
CGC46_RS16110	COG2966	Psort location CytoplasmicMembrane, score
CGC46_RS16125	COG1484	DNA-dependent DNA replication
CGC46_RS16140	COG1063	alcohol dehydrogenase
CGC46_RS16145	COG1802	Transcriptional regulator
CGC46_RS16150	COG2271	Major facilitator Superfamily
CGC46_RS16155	COG0840	transmembrane signaling receptor activity
CGC46_RS16160	COG1846	Transcriptional regulator
CGC46_RS16165	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGC46_RS16170	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS16175	COG3384	dioxygenase
CGC46_RS16185	COG3971	2-oxopent-4-enoate hydratase activity
CGC46_RS16205	COG2368	4-hydroxyphenylacetate
CGC46_RS16210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGC46_RS16220	COG1966	Carbon starvation protein
CGC46_RS16225	COG2879	small protein
CGC46_RS16230	COG0523	cobalamin synthesis protein
CGC46_RS16240	COG5457	Domain of unknown function (DUF1127)
CGC46_RS16245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGC46_RS16255	COG2814	Major facilitator Superfamily
CGC46_RS16260	COG2733	membrane
CGC46_RS16265	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CGC46_RS16270	COG1924	4 iron, 4 sulfur cluster binding
CGC46_RS16285	COG0477	Major facilitator Superfamily
CGC46_RS16300	COG3366	ferrous iron transmembrane transporter activity
CGC46_RS16305	COG0700	Nucleoside recognition
CGC46_RS16310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CGC46_RS16315	COG0583	DNA-binding transcription factor activity
CGC46_RS16335	COG2186	Transcriptional regulator
CGC46_RS16345	COG0246	Mannitol dehydrogenase
CGC46_RS16360	COG3539	Fimbrial protein
CGC46_RS16365	COG3539	Fimbrial protein
CGC46_RS16370	COG3539	Fimbrial protein
CGC46_RS16375	COG3188	usher protein
CGC46_RS16380	COG3121	Chaperone
CGC46_RS16385	COG3539	Fimbrial protein
CGC46_RS16390	COG3539	Fimbrial protein
CGC46_RS16395	COG4974	Belongs to the 'phage' integrase family
CGC46_RS16400	COG0582	viral genome integration into host DNA
CGC46_RS16410	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CGC46_RS16415	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CGC46_RS16435	COG1401	restriction endodeoxyribonuclease activity
CGC46_RS16490	COG2815	serine threonine protein kinase
CGC46_RS16490	COG0515	serine threonine protein kinase
CGC46_RS16505	COG1064	alcohol dehydrogenase
CGC46_RS16510	COG3265	gluconokinase activity
CGC46_RS16515	COG1063	alcohol dehydrogenase
CGC46_RS16520	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS16525	COG2610	gluconate transmembrane transporter activity
CGC46_RS16530	COG1609	Transcriptional regulator
CGC46_RS16535	COG0433	COG0433 Predicted ATPase
CGC46_RS16540	COG0795	lipopolysaccharide-transporting ATPase activity
CGC46_RS16545	COG0795	lipopolysaccharide-transporting ATPase activity
CGC46_RS16555	COG2927	DNA polymerase III (CHI subunit)
CGC46_RS16560	COG0525	valine-tRNA ligase activity
CGC46_RS16570	COG0456	acetyltransferase
CGC46_RS16575	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CGC46_RS16590	COG2731	YhcH YjgK YiaL family protein
CGC46_RS16595	COG1309	transcriptional regulator
CGC46_RS16600	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS16605	COG0251	oxidation-reduction process
CGC46_RS16630	COG0251	oxidation-reduction process
CGC46_RS16635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CGC46_RS16645	COG1609	Transcriptional regulator
CGC46_RS16650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS16650	COG1263	PTS System
CGC46_RS16655	COG0366	Alpha amylase catalytic
CGC46_RS16660	COG1328	CTP reductase activity
CGC46_RS16665	COG0602	queuosine metabolic process
CGC46_RS16670	COG3783	Cytochrome b(562)
CGC46_RS16675	COG0312	modulator of DNA gyrase
CGC46_RS16685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CGC46_RS16695	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGC46_RS16700	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGC46_RS16705	COG1129	ABC transporter
CGC46_RS16710	COG1879	ABC-type sugar transport system periplasmic component
CGC46_RS16715	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CGC46_RS16720	COG2105	PFAM AIG2 family protein
CGC46_RS16725	COG2911	Protein conserved in bacteria
CGC46_RS16730	COG0729	surface antigen
CGC46_RS16745	COG1253	flavin adenine dinucleotide binding
CGC46_RS16755	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CGC46_RS16760	COG1218	3'(2'),5'-bisphosphate nucleotidase
CGC46_RS16765	COG0737	Belongs to the 5'-nucleotidase family
CGC46_RS16770	COG1733	regulation of RNA biosynthetic process
CGC46_RS16775	COG0702	epimerase
CGC46_RS16780	COG0697	spore germination
CGC46_RS16790	COG1113	amino acid transport
CGC46_RS16795	COG0545	Peptidyl-prolyl cis-trans isomerase
CGC46_RS16805	COG3061	Opacity-associated protein A
CGC46_RS16810	COG1309	transcriptional regulator
CGC46_RS16825	COG1024	Enoyl-CoA hydratase
CGC46_RS16830	COG4670	ketone body catabolic process
CGC46_RS16835	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CGC46_RS16840	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CGC46_RS16850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CGC46_RS16860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CGC46_RS16905	COG3037	sugar-specific permease SgaT UlaA
CGC46_RS16920	COG1073	alpha beta
CGC46_RS16925	COG3650	response to hydrogen peroxide
CGC46_RS16935	COG1960	acyl-CoA dehydrogenase activity
CGC46_RS16940	COG0754	glutathionylspermidine amidase activity
CGC46_RS16945	COG5463	Belongs to the UPF0441 family
CGC46_RS16950	COG3766	membrane
CGC46_RS16960	COG1842	Phage shock protein A
CGC46_RS16965	COG3789	protein conserved in bacteria
CGC46_RS16975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGC46_RS16980	COG0557	exoribonuclease II activity
CGC46_RS16995	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CGC46_RS17000	COG0330	HflC and HflK could
CGC46_RS17005	COG0330	HflC and HflK could
CGC46_RS17010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CGC46_RS17030	COG0860	N-Acetylmuramoyl-L-alanine amidase
CGC46_RS17035	COG0802	atpase or kinase
CGC46_RS17040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CGC46_RS17040	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CGC46_RS17045	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CGC46_RS17085	COG3264	Mechanosensitive ion channel
CGC46_RS17085	COG1511	domain protein
CGC46_RS17100	COG0531	amino acid
CGC46_RS17110	COG1053	succinate dehydrogenase
CGC46_RS17115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CGC46_RS17130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CGC46_RS17135	COG3040	lipid binding
CGC46_RS17140	COG2076	Multidrug Resistance protein
CGC46_RS17145	COG5510	response to toxic substance
CGC46_RS17150	COG5510	response to toxic substance
CGC46_RS17160	COG1509	lysine 2,3-aminomutase activity
CGC46_RS17185	COG0531	amino acid
CGC46_RS17190	COG3030	protein affecting phage T7 exclusion by the F plasmid
CGC46_RS17195	COG1027	Aspartate ammonia-lyase
CGC46_RS17200	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CGC46_RS17215	COG1309	transcriptional regulator
CGC46_RS17225	COG0582	viral genome integration into host DNA
CGC46_RS17245	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS17250	COG2433	Pfam Transposase IS66
CGC46_RS17350	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS17355	COG4372	Transposase
CGC46_RS17360	COG3710	Transcriptional regulator
CGC46_RS17365	COG0531	amino acid
CGC46_RS17370	COG1982	Orn Lys Arg decarboxylase major
CGC46_RS17375	COG3104	oligopeptide transport
CGC46_RS17380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CGC46_RS17400	COG2388	GCN5-related N-acetyl-transferase
CGC46_RS17405	COG3592	Divergent 4Fe-4S mono-cluster
CGC46_RS17410	COG3290	protein histidine kinase activity
CGC46_RS17415	COG4565	transcriptional regulatory protein
CGC46_RS17430	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CGC46_RS17435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CGC46_RS17435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CGC46_RS17440	COG3647	Membrane
CGC46_RS17450	COG2211	Major facilitator Superfamily
CGC46_RS17455	COG1486	melibiose metabolic process
CGC46_RS17460	COG2169	Transcriptional regulator
CGC46_RS17465	COG1982	Orn Lys Arg decarboxylase major
CGC46_RS17470	COG2207	Transcriptional regulator
CGC46_RS17475	COG0531	amino acid
CGC46_RS17480	COG2194	sulfuric ester hydrolase activity
CGC46_RS17485	COG0745	RESPONSE REGULATOR receiver
CGC46_RS17490	COG0642	Histidine kinase
CGC46_RS17500	COG0477	Major facilitator Superfamily
CGC46_RS17520	COG2824	Alkylphosphonate utilization operon protein PhnA
CGC46_RS17525	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CGC46_RS17535	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CGC46_RS17540	COG3639	organic phosphonate transmembrane transporter activity
CGC46_RS17545	COG2188	Transcriptional regulator
CGC46_RS17550	COG3624	Phosphonate C-P lyase system protein PhnG
CGC46_RS17555	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CGC46_RS17560	COG3626	phosphonate metabolism
CGC46_RS17565	COG3627	carbon phosphorus lyase activity
CGC46_RS17570	COG4107	phosphonate C-P lyase system protein PhnK
CGC46_RS17575	COG4778	phosphonate C-P lyase system protein PhnL
CGC46_RS17580	COG3454	Phosphonate metabolism
CGC46_RS17585	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CGC46_RS17590	COG0456	acetyltransferase
CGC46_RS17595	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CGC46_RS17605	COG0698	ribose 5-phosphate isomerase
CGC46_RS17615	COG1737	Transcriptional regulator
CGC46_RS17620	COG1879	ABC-type sugar transport system periplasmic component
CGC46_RS17625	COG1129	ABC transporter
CGC46_RS17630	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGC46_RS17635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CGC46_RS17640	COG1940	carbohydrate kinase activity
CGC46_RS17645	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CGC46_RS17655	COG1566	PFAM secretion protein HlyD family protein
CGC46_RS17660	COG1289	transmembrane transporter activity
CGC46_RS17675	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CGC46_RS17680	COG1301	dicarboxylic acid transport
CGC46_RS17690	COG4235	cytochrome complex assembly
CGC46_RS17695	COG3088	subunit of a heme lyase
CGC46_RS17700	COG1138	Cytochrome C-type biogenesis protein
CGC46_RS17705	COG3301	Polysulphide reductase, NrfD
CGC46_RS17710	COG0437	4 iron, 4 sulfur cluster binding
CGC46_RS17715	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CGC46_RS17730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CGC46_RS17735	COG3162	membrane
CGC46_RS17750	COG0025	NhaP-type Na H and K H
CGC46_RS17755	COG2252	PERMEase
CGC46_RS17775	COG0789	Transcriptional regulator
CGC46_RS17780	COG2207	Transcriptional regulator
CGC46_RS17785	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CGC46_RS17800	COG0629	single-stranded DNA binding
CGC46_RS17805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CGC46_RS17810	COG2315	Protein conserved in bacteria
CGC46_RS17815	COG0432	Pfam Uncharacterised protein family UPF0047
CGC46_RS17820	COG3700	Belongs to the class B bacterial acid phosphatase family
CGC46_RS17830	COG1448	Aminotransferase
CGC46_RS17835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGC46_RS17840	COG0305	Participates in initiation and elongation during chromosome replication
CGC46_RS17855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGC46_RS17995	COG1030	water channel activity
CGC46_RS18015	COG4220	transposase activity
CGC46_RS18050	COG3772	lysozyme
CGC46_RS18115	COG1403	HNH endonuclease
CGC46_RS18125	COG0305	Participates in initiation and elongation during chromosome replication
CGC46_RS18130	COG1484	DNA-dependent DNA replication
CGC46_RS18150	COG3646	Phage regulatory protein
CGC46_RS18180	COG5532	Uncharacterized conserved protein (DUF2303)
CGC46_RS18185	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CGC46_RS18195	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CGC46_RS18245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGC46_RS18255	COG0735	belongs to the Fur family
CGC46_RS18260	COG3237	CsbD-like
CGC46_RS18265	COG0534	Mate efflux family protein
CGC46_RS18275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CGC46_RS18320	COG3842	ATPase activity
CGC46_RS18330	COG2182	Extracellular solute-binding protein
CGC46_RS18335	COG1175	transmembrane transport
CGC46_RS18340	COG3833	ABC-type maltose transport systems, permease component
CGC46_RS18345	COG2814	Major facilitator Superfamily
CGC46_RS18345	COG0477	Major facilitator Superfamily
CGC46_RS18360	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CGC46_RS18390	COG0527	aspartate kinase activity
CGC46_RS18400	COG1187	pseudouridine synthase activity
CGC46_RS18445	COG1283	sodium-dependent phosphate transmembrane transporter activity
CGC46_RS18450	COG1410	methionine synthase
CGC46_RS18450	COG0646	methionine synthase
CGC46_RS18455	COG1414	Transcriptional regulator
CGC46_RS18470	COG2224	Isocitrate lyase
CGC46_RS18475	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CGC46_RS18485	COG0456	acetyltransferase
CGC46_RS18520	COG0151	Belongs to the GarS family
CGC46_RS18525	COG2204	response regulator
CGC46_RS18530	COG4191	Histidine kinase
CGC46_RS18540	COG3678	ATP-independent chaperone mediated protein folding
CGC46_RS18555	COG3068	Protein conserved in bacteria
CGC46_RS18595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CGC46_RS18600	COG2104	thiamine diphosphate biosynthetic process
CGC46_RS18610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CGC46_RS18655	COG0250	Participates in transcription elongation, termination and antitermination
CGC46_RS18660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGC46_RS18705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CGC46_RS18705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CGC46_RS18765	COG0583	DNA-binding transcription factor activity
CGC46_RS18780	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CGC46_RS18795	COG2194	sulfuric ester hydrolase activity
CGC46_RS18800	COG2207	Transcriptional regulator
CGC46_RS18805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS18810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CGC46_RS18815	COG1882	Formate acetyltransferase
CGC46_RS18820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS18825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS18830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS18830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGC46_RS18830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS18835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGC46_RS18840	COG0371	Dehydrogenase
CGC46_RS18845	COG3738	Protein conserved in bacteria
CGC46_RS18850	COG0697	spore germination
CGC46_RS18860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CGC46_RS18865	COG0527	aspartate kinase activity
CGC46_RS18865	COG0460	homoserine dehydrogenase
CGC46_RS18870	COG0626	cystathionine gamma-synthase activity
CGC46_RS18880	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CGC46_RS18890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CGC46_RS18895	COG1609	Transcriptional regulator
CGC46_RS18900	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CGC46_RS18915	COG1575	Belongs to the MenA family. Type 1 subfamily
CGC46_RS18930	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGC46_RS18940	COG1494	fructose-1,6-bisphosphatase
CGC46_RS18950	COG0589	response to stress
CGC46_RS18955	COG3691	Protein conserved in bacteria
CGC46_RS18960	COG3152	Membrane
CGC46_RS18980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CGC46_RS18995	COG3678	ATP-independent chaperone mediated protein folding
CGC46_RS19000	COG0745	RESPONSE REGULATOR receiver
CGC46_RS19005	COG2205	protein histidine kinase activity
CGC46_RS19010	COG2258	MOSC domain
CGC46_RS19030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CGC46_RS19070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS19075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS19075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS19080	COG1363	Peptidase, m42
CGC46_RS19085	COG3711	transcriptional antiterminator
CGC46_RS19085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS19105	COG3383	formate dehydrogenase (NAD+) activity
CGC46_RS19105	COG0243	molybdopterin cofactor binding
CGC46_RS19110	COG3383	formate dehydrogenase (NAD+) activity
CGC46_RS19110	COG0243	molybdopterin cofactor binding
CGC46_RS19115	COG0437	4 iron, 4 sulfur cluster binding
CGC46_RS19120	COG2864	formate dehydrogenase
CGC46_RS19130	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CGC46_RS19135	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CGC46_RS19150	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CGC46_RS19175	COG0456	acetyltransferase
CGC46_RS19190	COG1011	Hydrolase
CGC46_RS19200	COG0477	Major facilitator Superfamily
CGC46_RS19210	COG1063	alcohol dehydrogenase
CGC46_RS19215	COG3684	Belongs to the aldolase LacD family
CGC46_RS19225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC46_RS19230	COG1349	DNA-binding transcription factor activity
CGC46_RS19235	COG1217	gtp-binding protein TYPA
CGC46_RS19245	COG0174	glutamine synthetase
CGC46_RS19250	COG3852	Histidine kinase
CGC46_RS19255	COG2204	response regulator
CGC46_RS19265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CGC46_RS19280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGC46_RS19280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGC46_RS19290	COG0204	Acyl-transferase
CGC46_RS19295	COG5339	Protein conserved in bacteria
CGC46_RS19300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CGC46_RS19305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CGC46_RS19310	COG3084	Protein conserved in bacteria
CGC46_RS19315	COG0746	molybdenum cofactor guanylyltransferase activity
CGC46_RS19320	COG1763	Mo-molybdopterin cofactor biosynthetic process
CGC46_RS19350	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CGC46_RS19355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CGC46_RS19360	COG1739	Uncharacterized protein family UPF0029
CGC46_RS19380	COG0543	2 iron, 2 sulfur cluster binding
CGC46_RS19385	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CGC46_RS19390	COG0250	Participates in transcription elongation, termination and antitermination
CGC46_RS19400	COG0805	protein transport
CGC46_RS19405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGC46_RS19410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGC46_RS19420	COG3165	ubiquinone biosynthetic process from chorismate
CGC46_RS19430	COG1322	Protein conserved in bacteria
CGC46_RS19435	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CGC46_RS19440	COG0412	Dienelactone hydrolase
CGC46_RS19445	COG3157	Type VI secretion system effector, Hcp
CGC46_RS19465	COG0583	DNA-binding transcription factor activity
CGC46_RS19470	COG0697	spore germination
CGC46_RS19475	COG0561	phosphatase activity
CGC46_RS19480	COG2267	carboxylic ester hydrolase activity
CGC46_RS19485	COG1280	lysine exporter protein (LysE YggA)
CGC46_RS19490	COG1280	lysine exporter protein (LysE YggA)
CGC46_RS19495	COG0514	ATP-dependent DNA helicase (RecQ)
CGC46_RS19500	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CGC46_RS19505	COG2050	protein possibly involved in aromatic compounds catabolism
CGC46_RS19510	COG2962	Rard protein
CGC46_RS19540	COG0598	Magnesium transport protein CorA
CGC46_RS19545	COG3698	Phosphodiester glycosidase
CGC46_RS19550	COG0210	DNA helicase
CGC46_RS19555	COG1011	Hydrolase
CGC46_RS19565	COG3159	Protein conserved in bacteria
CGC46_RS19575	COG5567	small periplasmic lipoprotein
CGC46_RS19585	COG3072	Adenylate cyclase
CGC46_RS19600	COG1587	Uroporphyrinogen-III synthase
CGC46_RS19605	COG2959	enzyme of heme biosynthesis
CGC46_RS19610	COG3071	HemY protein
CGC46_RS19615	COG0641	radical SAM
CGC46_RS19640	COG1113	amino acid transport
CGC46_RS19660	COG2244	polysaccharide biosynthetic process
CGC46_RS19665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CGC46_RS19670	COG0456	acetyltransferase
CGC46_RS19675	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CGC46_RS19680	COG1088	dTDP-glucose 4,6-dehydratase activity
CGC46_RS19685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CGC46_RS19690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CGC46_RS19695	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CGC46_RS19700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGC46_RS19710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CGC46_RS19720	COG3118	belongs to the thioredoxin family
CGC46_RS19740	COG0210	DNA helicase
CGC46_RS19745	COG3692	DNA binding
CGC46_RS19750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CGC46_RS19760	COG0583	DNA-binding transcription factor activity
CGC46_RS19765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGC46_RS19775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGC46_RS19780	COG3978	acetolactate synthase activity
CGC46_RS19810	COG3085	chromosome segregation
CGC46_RS19850	COG2186	Transcriptional regulator
CGC46_RS19855	COG0477	Major facilitator Superfamily
CGC46_RS19860	COG1609	Transcriptional regulator
CGC46_RS19865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC46_RS19870	COG1879	ABC-type sugar transport system periplasmic component
CGC46_RS19875	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGC46_RS19880	COG1129	ABC transporter
CGC46_RS19910	COG1522	sequence-specific DNA binding
CGC46_RS19915	COG0716	FMN binding
CGC46_RS19930	COG3312	ion transport
CGC46_RS19985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGC46_RS20010	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CGC46_RS20015	COG0573	inorganic phosphate transmembrane transporter activity
CGC46_RS20020	COG0581	inorganic phosphate transmembrane transporter activity
CGC46_RS20025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CGC46_RS20030	COG0704	Plays a role in the regulation of phosphate uptake
CGC46_RS20035	COG3711	transcriptional antiterminator
CGC46_RS20040	COG2190	(PTS) system
CGC46_RS20040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS20040	COG1263	PTS System
CGC46_RS20045	COG2723	6-phospho-beta-galactosidase activity
CGC46_RS20055	COG2382	esterase
CGC46_RS20060	COG0363	glucosamine-6-phosphate deaminase activity
CGC46_RS20070	COG4372	Transposase
CGC46_RS20075	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS20095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGC46_RS20100	COG2252	PERMEase
CGC46_RS20105	COG0431	NADPH-dependent FMN reductase
CGC46_RS20110	COG2091	lysine biosynthetic process via aminoadipic acid
CGC46_RS20125	COG0814	amino acid
CGC46_RS20175	COG0592	DNA-directed DNA polymerase activity
CGC46_RS20185	COG0187	DNA topoisomerase II activity
CGC46_RS20190	COG3753	Protein conserved in bacteria
CGC46_RS20195	COG0561	phosphatase activity
CGC46_RS20205	COG2186	Transcriptional regulator
CGC46_RS20210	COG3734	2-keto-3-deoxy-galactonokinase
CGC46_RS20215	COG0800	Aldolase
CGC46_RS20225	COG2271	Major facilitator Superfamily
CGC46_RS20235	COG0823	Involved in the tonB-independent uptake of proteins
CGC46_RS20240	COG5645	(Lipo)protein
CGC46_RS20260	COG2188	Transcriptional regulator
CGC46_RS20275	COG2207	Transcriptional regulator
CGC46_RS20280	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGC46_RS20285	COG3119	arylsulfatase activity
CGC46_RS20295	COG2149	membrane
CGC46_RS20305	COG0641	radical SAM
CGC46_RS20310	COG2814	Major facilitator Superfamily
CGC46_RS20345	COG0028	Belongs to the TPP enzyme family
CGC46_RS20350	COG0440	acetolactate synthase activity
CGC46_RS20355	COG2197	response regulator
CGC46_RS20360	COG3851	Histidine kinase
CGC46_RS20365	COG2271	Major facilitator Superfamily
CGC46_RS20370	COG2271	Major facilitator Superfamily
CGC46_RS20380	COG2252	PERMEase
CGC46_RS20410	COG1464	Belongs to the NlpA lipoprotein family
CGC46_RS20415	COG0697	spore germination
CGC46_RS20420	COG2814	Major facilitator Superfamily
CGC46_RS20435	COG2211	Major facilitator Superfamily
CGC46_RS20440	COG1501	Belongs to the glycosyl hydrolase 31 family
CGC46_RS20445	COG2982	Protein involved in outer membrane biogenesis
CGC46_RS20450	COG2233	PERMEase
CGC46_RS20455	COG0786	glutamate:sodium symporter activity
CGC46_RS20465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CGC46_RS20470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGC46_RS20475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGC46_RS20485	COG0194	GDP metabolic process
CGC46_RS20495	COG2860	membrane
CGC46_RS20500	COG3645	SOS response
CGC46_RS20505	COG1561	YicC-like family, N-terminal region
CGC46_RS20535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CGC46_RS20565	COG1519	Transferase
CGC46_RS20570	COG0859	PFAM glycosyl transferase family 9
CGC46_RS20575	COG0438	transferase activity, transferring glycosyl groups
CGC46_RS20580	COG0515	serine threonine protein kinase
CGC46_RS20595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CGC46_RS20600	COG1442	glycosyl transferase family 8
CGC46_RS20605	COG1216	Glycosyl transferase, family 2
CGC46_RS20610	COG3307	-O-antigen
CGC46_RS20615	COG0859	PFAM glycosyl transferase family 9
CGC46_RS20620	COG0859	PFAM glycosyl transferase family 9
CGC46_RS20630	COG0156	8-amino-7-oxononanoate synthase activity
CGC46_RS20640	COG1216	Glycosyl transferase, family 2
CGC46_RS20645	COG2861	carbohydrate metabolic process
CGC46_RS20650	COG4942	peptidase
CGC46_RS20665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGC46_RS20670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CGC46_RS20685	COG1045	serine acetyltransferase
CGC46_RS20690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CGC46_RS20700	COG2186	Transcriptional regulator
CGC46_RS20705	COG1620	l-lactate permease
CGC46_RS20715	COG5295	Hep Hag repeat protein
CGC46_RS20740	COG3722	fumarate hydratase activity
CGC46_RS20750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS20750	COG2213	PTS system mannitol-specific
CGC46_RS20760	COG1566	PFAM secretion protein HlyD family protein
CGC46_RS20780	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CGC46_RS20785	COG3209	COG3209 Rhs family protein
CGC46_RS20795	COG3209	COG3209 Rhs family protein
CGC46_RS20800	COG0625	glutathione transferase activity
CGC46_RS20810	COG3276	selenocysteine insertion sequence binding
CGC46_RS20815	COG1454	alcohol dehydrogenase
CGC46_RS20820	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS20835	COG1566	PFAM secretion protein HlyD family protein
CGC46_RS20840	COG0583	DNA-binding transcription factor activity
CGC46_RS20845	COG3713	MltA-interacting MipA family protein
CGC46_RS20855	COG0235	Class ii aldolase
CGC46_RS20860	COG3623	hexulose-6-phosphate isomerase
CGC46_RS20865	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CGC46_RS20870	COG1070	Carbohydrate kinase
CGC46_RS20875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CGC46_RS20880	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CGC46_RS20885	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CGC46_RS20890	COG2731	YhcH YjgK YiaL family protein
CGC46_RS20900	COG1414	Transcriptional regulator
CGC46_RS20905	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS20910	COG3977	Valine--pyruvate aminotransferase
CGC46_RS20915	COG0366	Alpha amylase catalytic
CGC46_RS20920	COG2992	FlgJ-related protein
CGC46_RS20925	COG2207	Transcriptional regulator
CGC46_RS20925	COG1609	Transcriptional regulator
CGC46_RS20930	COG4214	carbohydrate transport
CGC46_RS20940	COG4213	ABC transporter substrate-binding protein
CGC46_RS20950	COG1070	Carbohydrate kinase
CGC46_RS20955	COG4682	membrane
CGC46_RS20960	COG4682	membrane
CGC46_RS20965	COG3274	enterobacterial common antigen metabolic process
CGC46_RS20990	COG1278	Cold shock
CGC46_RS20995	COG2944	sequence-specific DNA binding
CGC46_RS21010	COG2885	chlorophyll binding
CGC46_RS21015	COG0243	molybdopterin cofactor binding
CGC46_RS21020	COG0456	acetyltransferase
CGC46_RS21025	COG2818	Glycosylase
CGC46_RS21030	COG5571	outer membrane autotransporter
CGC46_RS21040	COG2223	nitrite transmembrane transporter activity
CGC46_RS21045	COG2194	sulfuric ester hydrolase activity
CGC46_RS21060	COG0747	negative chemotaxis
CGC46_RS21065	COG0601	transmembrane transport
CGC46_RS21070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGC46_RS21075	COG0444	Belongs to the ABC transporter superfamily
CGC46_RS21080	COG4608	Belongs to the ABC transporter superfamily
CGC46_RS21085	COG0814	amino acid
CGC46_RS21115	COG2194	sulfuric ester hydrolase activity
CGC46_RS21140	COG1215	transferase activity, transferring glycosyl groups
CGC46_RS21145	COG1215	transferase activity, transferring glycosyl groups
CGC46_RS21150	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CGC46_RS21155	COG3118	belongs to the thioredoxin family
CGC46_RS21155	COG0457	Tetratricopeptide repeat
CGC46_RS21160	COG2199	diguanylate cyclase activity
CGC46_RS21160	COG2200	EAL domain
CGC46_RS21175	COG0612	Peptidase, M16
CGC46_RS21190	COG2200	EAL domain
CGC46_RS21195	COG2982	Protein involved in outer membrane biogenesis
CGC46_RS21200	COG0477	Major facilitator Superfamily
CGC46_RS21205	COG1295	ribonuclease BN
CGC46_RS21210	COG0583	DNA-binding transcription factor activity
CGC46_RS21215	COG2197	response regulator
CGC46_RS21225	COG1858	cytochrome C peroxidase
CGC46_RS21230	COG0076	glutamate decarboxylase activity
CGC46_RS21240	COG2207	Transcriptional regulator
CGC46_RS21250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGC46_RS21255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC46_RS21265	COG2771	luxR family
CGC46_RS21270	COG3247	response to pH
CGC46_RS21285	COG1285	pathogenesis
CGC46_RS21290	COG2197	response regulator
CGC46_RS21300	COG3065	identical protein binding
CGC46_RS21320	COG1393	Belongs to the ArsC family
CGC46_RS21325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CGC46_RS21330	COG0640	Transcriptional regulator
CGC46_RS21345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGC46_RS21350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CGC46_RS21355	COG0339	signal peptide processing
CGC46_RS21365	COG3104	oligopeptide transport
CGC46_RS21375	COG0589	response to stress
CGC46_RS21385	COG0306	phosphate transporter
CGC46_RS21390	COG2081	HI0933 family
CGC46_RS21415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC46_RS21420	COG0842	Transport permease protein
CGC46_RS21420	COG1129	ABC transporter
CGC46_RS21425	COG0842	Transport permease protein
CGC46_RS21450	COG0444	Belongs to the ABC transporter superfamily
CGC46_RS21455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGC46_RS21460	COG0601	transmembrane transport
CGC46_RS21465	COG0747	negative chemotaxis
CGC46_RS21470	COG2091	lysine biosynthetic process via aminoadipic acid
CGC46_RS21475	COG0628	permease
CGC46_RS21490	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CGC46_RS21505	COG3714	YhhN family
CGC46_RS21515	COG3776	membrane
CGC46_RS21520	COG0742	ribosomal rna small subunit methyltransferase
CGC46_RS21525	COG0552	protein localization to endoplasmic reticulum
CGC46_RS21530	COG2884	Cell division ATP-binding protein ftsE
CGC46_RS21535	COG2177	Part of the ABC transporter FtsEX involved in
CGC46_RS21540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGC46_RS21545	COG0683	leucine binding
CGC46_RS21550	COG0456	acetyltransferase
CGC46_RS21560	COG0683	leucine binding
CGC46_RS21565	COG0559	Belongs to the binding-protein-dependent transport system permease family
CGC46_RS21570	COG4177	L-phenylalanine transmembrane transporter activity
CGC46_RS21575	COG0411	ABC transporter
CGC46_RS21580	COG0410	ABC transporter
CGC46_RS21585	COG1653	transport
CGC46_RS21590	COG1175	transmembrane transport
CGC46_RS21595	COG0395	ABC-type sugar transport system, permease component
CGC46_RS21600	COG3842	ATPase activity
CGC46_RS21605	COG0584	glycerophosphoryl diester phosphodiesterase
CGC46_RS21615	COG0405	Gamma-glutamyltransferase
CGC46_RS21635	COG3157	Type VI secretion system effector, Hcp
CGC46_RS21640	COG1247	-acetyltransferase
CGC46_RS21650	COG0673	inositol 2-dehydrogenase activity
CGC46_RS21655	COG1741	Belongs to the pirin family
CGC46_RS21660	COG1609	Transcriptional regulator
CGC46_RS21665	COG3265	gluconokinase activity
CGC46_RS21670	COG2610	gluconate transmembrane transporter activity
CGC46_RS21675	COG2095	MarC family integral membrane protein
CGC46_RS21680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CGC46_RS21705	COG0058	SHG alpha-glucan phosphorylase activity
CGC46_RS21730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGC46_RS21745	COG1349	DNA-binding transcription factor activity
CGC46_RS21750	COG4650	regulator
CGC46_RS21755	COG1690	Belongs to the RtcB family
CGC46_RS21770	COG0058	SHG alpha-glucan phosphorylase activity
CGC46_RS21775	COG1640	4-alpha-glucanotransferase
CGC46_RS21780	COG2610	gluconate transmembrane transporter activity
CGC46_RS21800	COG5464	transposase or invertase
CGC46_RS21815	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CGC46_RS21820	COG1918	ferrous iron import across plasma membrane
CGC46_RS21830	COG2183	response to ionizing radiation
CGC46_RS21835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CGC46_RS21865	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CGC46_RS21875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CGC46_RS21880	COG1011	Hydrolase
CGC46_RS21890	COG0494	nUDIX hydrolase
CGC46_RS21895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CGC46_RS21900	COG4972	Pilus assembly protein
CGC46_RS21905	COG3166	PFAM Fimbrial assembly family protein
CGC46_RS21920	COG4796	Type ii and iii secretion system protein
CGC46_RS21940	COG3266	domain, Protein
CGC46_RS21945	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CGC46_RS21950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CGC46_RS21960	COG0180	Tryptophanyl-tRNA synthetase
CGC46_RS21965	COG2188	Transcriptional regulator
CGC46_RS21975	COG3457	Alanine racemase
CGC46_RS21980	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CGC46_RS21985	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CGC46_RS22000	COG0626	cystathionine gamma-synthase activity
CGC46_RS22005	COG2188	Transcriptional regulator
CGC46_RS22015	COG1082	Xylose isomerase domain protein TIM barrel
CGC46_RS22025	COG2222	sugar isomerase
CGC46_RS22030	COG0531	amino acid
CGC46_RS22055	COG2116	formate transmembrane transporter activity
CGC46_RS22060	COG2146	nitrite reductase [NAD(P)H] activity
CGC46_RS22065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGC46_RS22075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CGC46_RS22085	COG2184	nucleotidyltransferase activity
CGC46_RS22090	COG0512	Glutamine amidotransferase of anthranilate synthase
CGC46_RS22095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CGC46_RS22100	COG1289	transmembrane transporter activity
CGC46_RS22105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGC46_RS22115	COG1765	OsmC-like protein
CGC46_RS22120	COG3954	Phosphoribulokinase
CGC46_RS22130	COG0429	hydrolase of the alpha beta-hydrolase fold
CGC46_RS22135	COG0488	(ABC) transporter
CGC46_RS22155	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CGC46_RS22160	COG1047	Peptidyl-prolyl cis-trans
CGC46_RS22170	COG0545	Peptidyl-prolyl cis-trans isomerase
CGC46_RS22175	COG2964	Protein conserved in bacteria
CGC46_RS22255	COG0089	rRNA binding
CGC46_RS22345	COG0201	protein transport
CGC46_RS22385	COG0789	Transcriptional regulator
CGC46_RS22390	COG3036	rescue of stalled ribosome
CGC46_RS22400	COG0569	domain protein
CGC46_RS22420	COG0758	DNA mediated transformation
CGC46_RS22430	COG0551	DNA topoisomerase type I activity
CGC46_RS22450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CGC46_RS22490	COG1126	abc transporter atp-binding protein
CGC46_RS22495	COG0765	amino acid transport
CGC46_RS22500	COG4597	amino acid ABC transporter
CGC46_RS22505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC46_RS22520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGC46_RS22525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC46_RS22535	COG1309	transcriptional regulator
CGC46_RS22545	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CGC46_RS22555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGC46_RS22565	COG4145	pantothenate transmembrane transporter activity
CGC46_RS22570	COG3924	membrane
CGC46_RS22575	COG0439	Biotin carboxylase
CGC46_RS22580	COG0511	ligase activity, forming carbon-carbon bonds
CGC46_RS22595	COG0604	alcohol dehydrogenase
CGC46_RS22615	COG1077	Cell shape determining protein MreB Mrl
CGC46_RS22620	COG1792	Involved in formation and maintenance of cell shape
CGC46_RS22625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CGC46_RS22635	COG1530	ribonuclease E activity
CGC46_RS22640	COG3164	Protein of unknown function
CGC46_RS22645	COG0312	modulator of DNA gyrase
CGC46_RS22650	COG0583	DNA-binding transcription factor activity
CGC46_RS22670	COG2732	(Barnase) inhibitor
CGC46_RS22690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGC46_RS22695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGC46_RS22700	COG3105	Protein conserved in bacteria
CGC46_RS22705	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CGC46_RS22725	COG0625	glutathione transferase activity
CGC46_RS22730	COG2969	positive regulation of protein catabolic process
CGC46_RS22735	COG3069	C4-dicarboxylate transmembrane transporter activity
CGC46_RS22770	COG2731	YhcH YjgK YiaL family protein
CGC46_RS22775	COG4804	nuclease activity
CGC46_RS22780	COG0493	'glutamate synthase
CGC46_RS22785	COG0070	glutamate synthase
CGC46_RS22785	COG0069	glutamate synthase activity
CGC46_RS22785	COG0067	glutamate synthase
CGC46_RS22800	COG1242	4 iron, 4 sulfur cluster binding
CGC46_RS22805	COG2198	Histidine kinase
CGC46_RS22805	COG5002	protein histidine kinase activity
CGC46_RS22805	COG0784	Response regulator, receiver
CGC46_RS22810	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CGC46_RS22820	COG0515	serine threonine protein kinase
CGC46_RS22825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS22840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CGC46_RS22845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CGC46_RS22850	COG1137	ATPase activity
CGC46_RS22855	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CGC46_RS22860	COG3117	lipopolysaccharide transmembrane transporter activity
CGC46_RS22865	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CGC46_RS22870	COG0517	IMP dehydrogenase activity
CGC46_RS22870	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CGC46_RS22875	COG0530	calcium, potassium:sodium antiporter activity
CGC46_RS22880	COG1127	ABC transporter
CGC46_RS22885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CGC46_RS22890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CGC46_RS22895	COG2854	intermembrane phospholipid transfer
CGC46_RS22900	COG3113	response to antibiotic
CGC46_RS22905	COG5007	Belongs to the BolA IbaG family
CGC46_RS22915	COG3423	Transcriptional regulator
CGC46_RS22920	COG0142	geranyltranstransferase activity
CGC46_RS22935	COG0697	spore germination
CGC46_RS22945	COG2027	D-alanyl-D-alanine carboxypeptidase
CGC46_RS22950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CGC46_RS22955	COG1534	Rna-binding protein
CGC46_RS22965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGC46_RS22970	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CGC46_RS22980	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGC46_RS22990	COG2194	sulfuric ester hydrolase activity
CGC46_RS23010	COG0195	Participates in both transcription termination and antitermination
CGC46_RS23050	COG0513	Belongs to the DEAD box helicase family
CGC46_RS23055	COG0814	amino acid
CGC46_RS23060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGC46_RS23065	COG0826	peptidase U32
CGC46_RS23070	COG0826	peptidase U32
CGC46_RS23075	COG3154	lipid carrier protein
CGC46_RS23080	COG3153	acetyltransferase
CGC46_RS23095	COG0693	protein deglycase activity
CGC46_RS23100	COG0702	epimerase
CGC46_RS23105	COG0701	Predicted permease
CGC46_RS23110	COG2823	Periplasmic or secreted lipoprotein
CGC46_RS23130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CGC46_RS23135	COG3539	Fimbrial protein
CGC46_RS23140	COG3188	usher protein
CGC46_RS23145	COG3121	Chaperone
CGC46_RS23150	COG3539	Fimbrial protein
CGC46_RS23155	COG0363	glucosamine-6-phosphate deaminase activity
CGC46_RS23160	COG3716	PTS system mannose fructose sorbose family IID component
CGC46_RS23165	COG3715	PTS system
CGC46_RS23170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS23180	COG2222	sugar isomerase
CGC46_RS23185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CGC46_RS23190	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS23195	COG3716	PTS system mannose fructose sorbose family IID component
CGC46_RS23205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS23220	COG1349	DNA-binding transcription factor activity
CGC46_RS23230	COG2002	toxin-antitoxin pair type II binding
CGC46_RS23235	COG2721	sulfolactate sulfo-lyase activity
CGC46_RS23240	COG2271	Major facilitator Superfamily
CGC46_RS23250	COG2084	Dehydrogenase
CGC46_RS23255	COG1929	Belongs to the glycerate kinase type-1 family
CGC46_RS23280	COG0583	DNA-binding transcription factor activity
CGC46_RS23290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGC46_RS23300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CGC46_RS23305	COG1882	Formate acetyltransferase
CGC46_RS23310	COG0251	oxidation-reduction process
CGC46_RS23315	COG1760	l-serine dehydratase
CGC46_RS23325	COG0814	amino acid
CGC46_RS23340	COG1741	Belongs to the pirin family
CGC46_RS23345	COG0583	DNA-binding transcription factor activity
CGC46_RS23355	COG3152	Membrane
CGC46_RS23360	COG3152	Membrane
CGC46_RS23365	COG0435	Glutathione S-transferase
CGC46_RS23370	COG2259	Doxx family
CGC46_RS23380	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CGC46_RS23385	COG4575	ribosome binding
CGC46_RS23390	COG1422	Protein of unknown function (DUF1090)
CGC46_RS23400	COG0586	Pfam SNARE associated Golgi protein
CGC46_RS23405	COG2186	Transcriptional regulator
CGC46_RS23435	COG2271	Major facilitator Superfamily
CGC46_RS23445	COG2721	sulfolactate sulfo-lyase activity
CGC46_RS23455	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CGC46_RS23460	COG0861	Integral membrane protein TerC family
CGC46_RS23465	COG0673	inositol 2-dehydrogenase activity
CGC46_RS23470	COG2949	membrane
CGC46_RS23475	COG1451	nucleotide metabolic process
CGC46_RS23490	COG4680	protein conserved in bacteria
CGC46_RS23495	COG5499	transcription regulator containing HTH domain
CGC46_RS23500	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGC46_RS23500	COG1902	pentaerythritol trinitrate reductase activity
CGC46_RS23505	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CGC46_RS23505	COG3408	Glycogen debranching enzyme
CGC46_RS23515	COG0531	amino acid
CGC46_RS23520	COG2731	YhcH YjgK YiaL family protein
CGC46_RS23525	COG3250	beta-galactosidase activity
CGC46_RS23530	COG1609	Transcriptional regulator
CGC46_RS23540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGC46_RS23555	COG0840	transmembrane signaling receptor activity
CGC46_RS23560	COG1695	Transcriptional regulator
CGC46_RS23570	COG2375	cellular response to nickel ion
CGC46_RS23595	COG4983	Phage plasmid primase, P4 family domain protein
CGC46_RS23615	COG4372	Transposase
CGC46_RS23620	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS23625	COG4372	Transposase
CGC46_RS23630	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS23695	COG1358	cellular component organization or biogenesis
CGC46_RS23730	COG4372	Transposase
CGC46_RS23775	COG0254	rRNA binding
CGC46_RS23805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CGC46_RS23810	COG2194	sulfuric ester hydrolase activity
CGC46_RS23850	COG0804	urea catabolic process
CGC46_RS23900	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS23905	COG4372	Transposase
CGC46_RS23995	COG2003	Belongs to the UPF0758 family
CGC46_RS24040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGC46_RS24050	COG0358	DNA primase activity
CGC46_RS24055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CGC46_RS24070	COG0471	metal ion transport
CGC46_RS24075	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CGC46_RS24080	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CGC46_RS24090	COG0583	DNA-binding transcription factor activity
CGC46_RS24100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CGC46_RS24115	COG4991	sh3 domain protein
CGC46_RS24125	COG3025	triphosphatase activity
CGC46_RS24150	COG2268	Band 7 protein
CGC46_RS24155	COG1585	Membrane protein implicated in regulation of membrane protease activity
CGC46_RS24165	COG3539	Fimbrial protein
CGC46_RS24185	COG3188	usher protein
CGC46_RS24190	COG3539	Fimbrial protein
CGC46_RS24195	COG2960	long-chain fatty acid transporting porin activity
CGC46_RS24215	COG3384	dioxygenase
CGC46_RS24220	COG0754	glutathionylspermidine amidase activity
CGC46_RS24235	COG1538	Outer membrane efflux protein
CGC46_RS24240	COG0494	nUDIX hydrolase
CGC46_RS24245	COG3151	Protein conserved in bacteria
CGC46_RS24250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CGC46_RS24255	COG3150	esterase
CGC46_RS24260	COG0187	DNA topoisomerase II activity
CGC46_RS24265	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CGC46_RS24270	COG2249	NAD(P)H dehydrogenase (quinone) activity
CGC46_RS24285	COG0642	Histidine kinase
CGC46_RS24290	COG0745	RESPONSE REGULATOR receiver
CGC46_RS24295	COG3111	PFAM Bacterial OB fold (BOF) protein
CGC46_RS24300	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CGC46_RS24310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGC46_RS24315	COG0204	Acyl-transferase
CGC46_RS24320	COG2132	Multicopper oxidase
CGC46_RS24325	COG1032	radical SAM domain protein
CGC46_RS24330	COG4238	major outer membrane lipoprotein
CGC46_RS24340	COG0656	L-ascorbic acid biosynthetic process
CGC46_RS24345	COG1979	alcohol dehydrogenase
CGC46_RS24350	COG2207	Transcriptional regulator
CGC46_RS24355	COG0586	Pfam SNARE associated Golgi protein
CGC46_RS24360	COG0626	cystathionine gamma-synthase activity
CGC46_RS24370	COG0811	peptide transport
CGC46_RS24375	COG0848	biopolymer transport protein
CGC46_RS24380	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS24390	COG0667	Aldo Keto reductase
CGC46_RS24410	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CGC46_RS24415	COG0437	4 iron, 4 sulfur cluster binding
CGC46_RS24420	COG5557	Pfam Polysulphide reductase, NrfD
CGC46_RS24425	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CGC46_RS24430	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CGC46_RS24435	COG1773	rubredoxin
CGC46_RS24445	COG0298	carbon dioxide binding
CGC46_RS24450	COG0625	glutathione transferase activity
CGC46_RS24455	COG0754	glutathionylspermidine amidase activity
CGC46_RS24460	COG0306	phosphate transporter
CGC46_RS24465	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGC46_RS24470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGC46_RS24475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGC46_RS24480	COG2244	polysaccharide biosynthetic process
CGC46_RS24490	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CGC46_RS24495	COG0795	lipopolysaccharide-transporting ATPase activity
CGC46_RS24535	COG0318	PFAM AMP-dependent synthetase and ligase
CGC46_RS24545	COG0456	acetyltransferase
CGC46_RS24550	COG2186	Transcriptional regulator
CGC46_RS24555	COG0277	FAD linked oxidase domain protein
CGC46_RS24560	COG0277	FAD linked oxidase domain protein
CGC46_RS24565	COG0247	lactate metabolic process
CGC46_RS24570	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CGC46_RS24575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CGC46_RS24580	COG1620	l-lactate permease
CGC46_RS24595	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CGC46_RS24615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CGC46_RS24620	COG1459	type II secretion system
CGC46_RS24625	COG2165	general secretion pathway protein
CGC46_RS24655	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CGC46_RS24690	COG2003	Belongs to the UPF0758 family
CGC46_RS24970	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS24975	COG4372	Transposase
CGC46_RS25005	COG2003	Belongs to the UPF0758 family
CGC46_RS25015	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS25040	COG4372	Transposase
CGC46_RS25045	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS25055	COG4372	Transposase
CGC46_RS25060	COG0582	viral genome integration into host DNA
CGC46_RS25070	COG1811	Na channel or pump
CGC46_RS25080	COG1982	Orn Lys Arg decarboxylase major
CGC46_RS25085	COG2211	Major facilitator Superfamily
CGC46_RS25100	COG1194	a g-specific adenine glycosylase
CGC46_RS25115	COG3171	Protein conserved in bacteria
CGC46_RS25125	COG0252	asparaginase activity
CGC46_RS25140	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CGC46_RS25145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CGC46_RS25150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CGC46_RS25165	COG0762	integral membrane protein
CGC46_RS25170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CGC46_RS25175	COG2805	Type II/IV secretion system protein
CGC46_RS25190	COG0189	ligase activity
CGC46_RS25195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CGC46_RS25200	COG2356	endonuclease I
CGC46_RS25210	COG2814	Major facilitator Superfamily
CGC46_RS25235	COG1166	arginine decarboxylase activity
CGC46_RS25250	COG0501	Belongs to the peptidase M48B family
CGC46_RS25255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CGC46_RS25260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS25265	COG2213	PTS system mannitol-specific
CGC46_RS25270	COG1063	alcohol dehydrogenase
CGC46_RS25275	COG1494	fructose-1,6-bisphosphatase
CGC46_RS25285	COG1072	(Pantothenic acid kinase))
CGC46_RS25290	COG1122	ATPase activity
CGC46_RS25295	COG1122	ATPase activity
CGC46_RS25330	COG0191	fructose-bisphosphate aldolase activity
CGC46_RS25340	COG0668	transmembrane transport
CGC46_RS25350	COG2968	Membrane
CGC46_RS25355	COG0583	DNA-binding transcription factor activity
CGC46_RS25360	COG0427	acetyl-CoA hydrolase
CGC46_RS25365	COG1024	Enoyl-CoA hydratase
CGC46_RS25370	COG1703	isobutyryl-CoA mutase activity
CGC46_RS25375	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGC46_RS25375	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGC46_RS25395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGC46_RS25415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CGC46_RS25440	COG0006	proline dipeptidase activity
CGC46_RS25445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGC46_RS25450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGC46_RS25470	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS25475	COG2723	6-phospho-beta-galactosidase activity
CGC46_RS25485	COG1272	protein, Hemolysin III
CGC46_RS25495	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CGC46_RS25505	COG0716	FMN binding
CGC46_RS25510	COG4974	Belongs to the 'phage' integrase family
CGC46_RS25515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CGC46_RS25520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CGC46_RS25545	COG2233	PERMEase
CGC46_RS25555	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS25555	COG0493	'glutamate synthase
CGC46_RS25560	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS25565	COG2252	PERMEase
CGC46_RS25570	COG0402	S-adenosylhomocysteine deaminase activity
CGC46_RS25575	COG2233	PERMEase
CGC46_RS25580	COG2080	2 iron, 2 sulfur cluster binding
CGC46_RS25580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CGC46_RS25585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CGC46_RS25590	COG0402	S-adenosylhomocysteine deaminase activity
CGC46_RS25595	COG0493	'glutamate synthase
CGC46_RS25595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS25600	COG2068	MobA-Related Protein
CGC46_RS25605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGC46_RS25610	COG3608	succinylglutamate desuccinylase aspartoacylase
CGC46_RS25610	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CGC46_RS25615	COG0549	Belongs to the carbamate kinase family
CGC46_RS25625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGC46_RS25630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGC46_RS25635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CGC46_RS25640	COG3829	transcription factor binding
CGC46_RS25645	COG2080	2 iron, 2 sulfur cluster binding
CGC46_RS25650	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CGC46_RS25655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CGC46_RS25665	COG4942	peptidase
CGC46_RS25685	COG0814	amino acid
CGC46_RS25690	COG0183	Belongs to the thiolase family
CGC46_RS25700	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS25705	COG2814	Major facilitator Superfamily
CGC46_RS25710	COG1794	racemase activity, acting on amino acids and derivatives
CGC46_RS25715	COG0583	DNA-binding transcription factor activity
CGC46_RS25725	COG1609	Transcriptional regulator
CGC46_RS25740	COG0667	Aldo Keto reductase
CGC46_RS25750	COG0861	Integral membrane protein TerC family
CGC46_RS25765	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CGC46_RS25780	COG2165	general secretion pathway protein
CGC46_RS25785	COG4795	General secretion pathway protein
CGC46_RS25795	COG4967	type IV pilus modification protein PilV
CGC46_RS25800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CGC46_RS25810	COG1074	ATP-dependent DNA helicase activity
CGC46_RS25815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CGC46_RS25820	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CGC46_RS25820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CGC46_RS25830	COG0860	N-Acetylmuramoyl-L-alanine amidase
CGC46_RS25855	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CGC46_RS25860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CGC46_RS25865	COG2166	iron-sulfur cluster assembly
CGC46_RS25870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CGC46_RS25880	COG0583	DNA-binding transcription factor activity
CGC46_RS25885	COG2363	Small membrane protein
CGC46_RS25895	COG1349	DNA-binding transcription factor activity
CGC46_RS25905	COG1070	Carbohydrate kinase
CGC46_RS25915	COG0738	Major facilitator superfamily
CGC46_RS25920	COG0235	Class ii aldolase
CGC46_RS25925	COG1454	alcohol dehydrogenase
CGC46_RS25935	COG1760	l-serine dehydratase
CGC46_RS25940	COG0814	amino acid
CGC46_RS25945	COG1611	Belongs to the LOG family
CGC46_RS25960	COG3098	single-species biofilm formation
CGC46_RS25965	COG0564	pseudouridine synthase activity
CGC46_RS25970	COG0716	FMN binding
CGC46_RS25975	COG2271	Major facilitator Superfamily
CGC46_RS25980	COG4948	Mandelate Racemase Muconate Lactonizing
CGC46_RS25985	COG4948	Mandelate Racemase Muconate Lactonizing
CGC46_RS25990	COG3437	response regulator, receiver
CGC46_RS25990	COG2205	protein histidine kinase activity
CGC46_RS25990	COG3850	Histidine kinase
CGC46_RS25990	COG4999	Histidine kinase
CGC46_RS26000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGC46_RS26005	COG2336	PFAM SpoVT AbrB
CGC46_RS26010	COG2337	Toxic component of a toxin-antitoxin (TA) module
CGC46_RS26015	COG3956	TIGRFAM MazG family protein
CGC46_RS26040	COG0602	queuosine metabolic process
CGC46_RS26045	COG1070	Carbohydrate kinase
CGC46_RS26050	COG2223	nitrite transmembrane transporter activity
CGC46_RS26055	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS26060	COG0277	FAD linked oxidase domain protein
CGC46_RS26065	COG0477	Major facilitator Superfamily
CGC46_RS26070	COG2086	electron transfer activity
CGC46_RS26075	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CGC46_RS26080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CGC46_RS26085	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CGC46_RS26090	COG0644	oxidoreductase
CGC46_RS26095	COG0720	synthase
CGC46_RS26105	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGC46_RS26150	COG1857	crispr-associated protein
CGC46_RS26165	COG1518	maintenance of DNA repeat elements
CGC46_RS26170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CGC46_RS26175	COG2234	aminopeptidase activity
CGC46_RS26230	COG4942	peptidase
CGC46_RS26230	COG1388	LysM domain
CGC46_RS26235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGC46_RS26250	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CGC46_RS26260	COG2610	gluconate transmembrane transporter activity
CGC46_RS26265	COG3622	Belongs to the hyi family
CGC46_RS26270	COG0235	Class ii aldolase
CGC46_RS26275	COG3395	kinase activity
CGC46_RS26280	COG2084	Dehydrogenase
CGC46_RS26285	COG1349	DNA-binding transcription factor activity
CGC46_RS26290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CGC46_RS26305	COG3604	Transcriptional regulator
CGC46_RS26310	COG0309	Hydrogenase expression formation protein (HypE)
CGC46_RS26315	COG0409	Hydrogenase expression formation protein
CGC46_RS26320	COG0298	carbon dioxide binding
CGC46_RS26325	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CGC46_RS26330	COG0375	protein maturation
CGC46_RS26340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS26345	COG0651	ATP synthesis coupled electron transport
CGC46_RS26350	COG0650	Formate hydrogenlyase subunit 4
CGC46_RS26355	COG3261	NADH dehydrogenase
CGC46_RS26355	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CGC46_RS26360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGC46_RS26365	COG3260	NADH ubiquinone oxidoreductase 20
CGC46_RS26375	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CGC46_RS26385	COG4680	protein conserved in bacteria
CGC46_RS26390	COG5499	transcription regulator containing HTH domain
CGC46_RS26395	COG2723	6-phospho-beta-galactosidase activity
CGC46_RS26400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS26400	COG1263	PTS System
CGC46_RS26405	COG1609	Transcriptional regulator
CGC46_RS26410	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS26415	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CGC46_RS26440	COG1349	DNA-binding transcription factor activity
CGC46_RS26445	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS26450	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS26460	COG3732	PTS system glucitol sorbitol-specific
CGC46_RS26465	COG3730	PTS system glucitol sorbitol-specific
CGC46_RS26470	COG2951	lytic endotransglycosylase activity
CGC46_RS26475	COG1546	Belongs to the CinA family
CGC46_RS26495	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CGC46_RS26525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGC46_RS26530	COG1238	metal cluster binding
CGC46_RS26545	COG2814	Major facilitator Superfamily
CGC46_RS26550	COG1566	PFAM secretion protein HlyD family protein
CGC46_RS26555	COG1846	Transcriptional regulator
CGC46_RS26565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CGC46_RS26570	COG2814	Major facilitator Superfamily
CGC46_RS26580	COG2113	Glycine betaine
CGC46_RS26585	COG4176	ABC-type proline glycine betaine transport system permease component
CGC46_RS26590	COG4175	Glycine betaine
CGC46_RS26595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGC46_RS26600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGC46_RS26610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CGC46_RS26615	COG4575	ribosome binding
CGC46_RS26630	COG2916	Histone family protein nucleoid-structuring protein H-NS
CGC46_RS26635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGC46_RS26640	COG0640	Transcriptional regulator
CGC46_RS26645	COG0401	homolog of Blt101
CGC46_RS26650	COG1652	LysM domain
CGC46_RS26655	COG1802	Transcriptional regulator
CGC46_RS26660	COG1113	amino acid transport
CGC46_RS26665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGC46_RS26670	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS26675	COG0579	oxidoreductase
CGC46_RS26685	COG0366	Alpha amylase catalytic
CGC46_RS26740	COG4974	Belongs to the 'phage' integrase family
CGC46_RS26880	COG3772	lysozyme
CGC46_RS27000	COG2032	superoxide dismutase activity
CGC46_RS27015	COG5301	cellulose 1,4-beta-cellobiosidase activity
CGC46_RS27060	COG2867	negative regulation of translational initiation
CGC46_RS27070	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CGC46_RS27075	COG0497	DNA recombination
CGC46_RS27095	COG4536	flavin adenine dinucleotide binding
CGC46_RS27100	COG4137	Cytochrome C assembly protein
CGC46_RS27105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CGC46_RS27130	COG2885	chlorophyll binding
CGC46_RS27150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CGC46_RS27155	COG0287	Prephenate dehydrogenase
CGC46_RS27155	COG1605	Chorismate mutase
CGC46_RS27160	COG1605	Chorismate mutase
CGC46_RS27160	COG0077	Prephenate dehydratase
CGC46_RS27170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CGC46_RS27180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CGC46_RS27185	COG0564	pseudouridine synthase activity
CGC46_RS27195	COG0542	response to heat
CGC46_RS27225	COG0477	Major facilitator Superfamily
CGC46_RS27230	COG5544	Lipoprotein
CGC46_RS27235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGC46_RS27240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGC46_RS27240	COG1042	CoA-binding domain protein
CGC46_RS27240	COG0045	succinate-CoA ligase (ADP-forming) activity
CGC46_RS27245	COG3148	PFAM DTW domain containing protein
CGC46_RS27250	COG3118	belongs to the thioredoxin family
CGC46_RS27260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGC46_RS27280	COG0583	DNA-binding transcription factor activity
CGC46_RS27285	COG0513	Belongs to the DEAD box helicase family
CGC46_RS27295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CGC46_RS27300	COG1595	DNA-templated transcription, initiation
CGC46_RS27305	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CGC46_RS27310	COG3026	antisigma factor binding
CGC46_RS27315	COG3086	response to oxidative stress
CGC46_RS27325	COG0681	Belongs to the peptidase S26 family
CGC46_RS27350	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CGC46_RS27375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS27380	COG1737	Transcriptional regulator
CGC46_RS27385	COG0560	Phosphoserine phosphatase
CGC46_RS27400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGC46_RS27400	COG0047	phosphoribosylformylglycinamidine synthase activity
CGC46_RS27405	COG2205	protein histidine kinase activity
CGC46_RS27410	COG3170	Tfp pilus assembly protein FimV
CGC46_RS27415	COG2204	response regulator
CGC46_RS27420	COG0347	Belongs to the P(II) protein family
CGC46_RS27425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGC46_RS27425	COG1017	nitric oxide dioxygenase activity
CGC46_RS27435	COG1940	carbohydrate kinase activity
CGC46_RS27440	COG0457	Tetratricopeptide repeat
CGC46_RS27445	COG1879	ABC-type sugar transport system periplasmic component
CGC46_RS27450	COG1129	ABC transporter
CGC46_RS27455	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGC46_RS27460	COG1063	alcohol dehydrogenase
CGC46_RS27465	COG2017	converts alpha-aldose to the beta-anomer
CGC46_RS27470	COG2259	Doxx family
CGC46_RS27495	COG4638	Rieske (2fe-2S)
CGC46_RS27500	COG0583	DNA-binding transcription factor activity
CGC46_RS27505	COG2814	Major facilitator Superfamily
CGC46_RS27510	COG3711	transcriptional antiterminator
CGC46_RS27515	COG1073	alpha beta
CGC46_RS27520	COG0483	inositol monophosphate 1-phosphatase activity
CGC46_RS27540	COG0822	iron-sulfur transferase activity
CGC46_RS27560	COG0633	Ferredoxin
CGC46_RS27565	COG2975	iron-sulfur cluster assembly
CGC46_RS27580	COG2897	thiosulfate sulfurtransferase activity
CGC46_RS27585	COG2373	Large extracellular alpha-helical protein
CGC46_RS27590	COG4953	penicillin-binding protein 1C
CGC46_RS27625	COG2976	Protein conserved in bacteria
CGC46_RS27640	COG1645	bacterial-type flagellum-dependent swarming motility
CGC46_RS27650	COG0516	GMP reductase activity
CGC46_RS27650	COG0517	IMP dehydrogenase activity
CGC46_RS27665	COG3133	Outer membrane lipoprotein
CGC46_RS27685	COG2200	EAL domain
CGC46_RS27690	COG0248	Ppx GppA phosphatase
CGC46_RS27695	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CGC46_RS27700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CGC46_RS27720	COG2233	PERMEase
CGC46_RS27730	COG1393	Belongs to the ArsC family
CGC46_RS27735	COG4783	chaperone-mediated protein folding
CGC46_RS27740	COG0628	permease
CGC46_RS27750	COG2116	formate transmembrane transporter activity
CGC46_RS27755	COG3604	Transcriptional regulator
CGC46_RS27765	COG3260	NADH ubiquinone oxidoreductase 20
CGC46_RS27770	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGC46_RS27775	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CGC46_RS27775	COG3261	NADH dehydrogenase
CGC46_RS27780	COG0651	ATP synthesis coupled electron transport
CGC46_RS27785	COG4237	Hydrogenase 4 membrane
CGC46_RS27795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CGC46_RS27800	COG0650	Formate hydrogenlyase subunit 4
CGC46_RS27810	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS27815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CGC46_RS27820	COG2716	regulation of RNA biosynthetic process
CGC46_RS27830	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CGC46_RS27850	COG2321	neutral zinc metallopeptidase
CGC46_RS27855	COG1444	tRNA N-acetyltransferase activity
CGC46_RS27875	COG1393	Belongs to the ArsC family
CGC46_RS27890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGC46_RS27895	COG3850	Histidine kinase
CGC46_RS27900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC46_RS27900	COG0493	'glutamate synthase
CGC46_RS27910	COG5342	invasion associated locus B
CGC46_RS27915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CGC46_RS27920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGC46_RS27925	COG0280	phosphate acetyltransferase
CGC46_RS27925	COG0281	malic enzyme
CGC46_RS27935	COG4810	utilization protein
CGC46_RS27940	COG4917	ethanolamine utilization protein
CGC46_RS27945	COG4766	ethanolamine catabolic process
CGC46_RS27950	COG4812	Cobalamin adenosyltransferase
CGC46_RS27955	COG0280	phosphate acetyltransferase
CGC46_RS27960	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CGC46_RS27965	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CGC46_RS27970	COG1012	belongs to the aldehyde dehydrogenase family
CGC46_RS27975	COG4820	ethanolamine utilization protein (EutJ)
CGC46_RS27980	COG1454	alcohol dehydrogenase
CGC46_RS27985	COG3192	ethanolamine utilization protein
CGC46_RS27990	COG4819	ethanolamine utilization protein
CGC46_RS27995	COG4303	Ethanolamine ammonia lyase large subunit
CGC46_RS28005	COG4816	utilization protein
CGC46_RS28010	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CGC46_RS28015	COG2207	Transcriptional regulator
CGC46_RS28025	COG0860	N-Acetylmuramoyl-L-alanine amidase
CGC46_RS28045	COG2837	iron assimilation
CGC46_RS28050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CGC46_RS28055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGC46_RS28055	COG1263	PTS System
CGC46_RS28070	COG1028	Short-chain dehydrogenase reductase Sdr
CGC46_RS28080	COG4150	thiosulfate binding
CGC46_RS28085	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CGC46_RS28090	COG4208	sulfate ABC transporter
CGC46_RS28095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CGC46_RS28100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CGC46_RS28115	COG2190	(PTS) system
CGC46_RS28120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGC46_RS28125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGC46_RS28130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CGC46_RS28150	COG3530	Putative quorum-sensing-regulated virulence factor
CGC46_RS28155	COG0385	Bile acid
CGC46_RS28160	COG0583	DNA-binding transcription factor activity
CGC46_RS28190	COG3415	Transposase
CGC46_RS28195	COG3415	Transposase
CGC46_RS28210	COG2199	diguanylate cyclase activity
CGC46_RS28210	COG2200	EAL domain
CGC46_RS28215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CGC46_RS28240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS28245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGC46_RS28250	COG0006	proline dipeptidase activity
CGC46_RS28255	COG1363	Peptidase, m42
CGC46_RS28265	COG2207	Transcriptional regulator
CGC46_RS28270	COG3279	Response regulator of the LytR AlgR family
CGC46_RS28275	COG3275	phosphorelay sensor kinase activity
CGC46_RS28280	COG0436	Aminotransferase
CGC46_RS28290	COG1560	Kdo2-lipid A biosynthetic process
CGC46_RS28320	COG0028	Belongs to the TPP enzyme family
CGC46_RS28325	COG0679	Auxin Efflux Carrier
CGC46_RS28330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGC46_RS28335	COG2198	Histidine kinase
CGC46_RS28335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC46_RS28335	COG2205	protein histidine kinase activity
CGC46_RS28335	COG0784	Response regulator, receiver
CGC46_RS28340	COG2197	response regulator
CGC46_RS28345	COG1566	PFAM secretion protein HlyD family protein
CGC46_RS28350	COG0477	Major facilitator Superfamily
CGC46_RS28360	COG2610	gluconate transmembrane transporter activity
CGC46_RS28365	COG0583	DNA-binding transcription factor activity
CGC46_RS28700	COG3772	lysozyme
CGC46_RS28740	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS28745	COG4372	Transposase
CGC46_RS28770	COG4372	Transposase
CGC46_RS28775	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS28905	COG2274	protein secretion by the type I secretion system
CGC46_RS28930	COG0726	polysaccharide deacetylase
CGC46_RS28935	COG0297	glycogen (starch) synthase activity
CGC46_RS28940	COG2194	sulfuric ester hydrolase activity
CGC46_RS28945	COG1560	Kdo2-lipid A biosynthetic process
CGC46_RS28955	COG4372	Transposase
CGC46_RS28960	COG3436	PFAM IS66 Orf2 family protein
CGC46_RS29090	COG1585	Membrane protein implicated in regulation of membrane protease activity
CGC46_RS29105	COG3468	outer membrane autotransporter barrel domain protein