locus-tag	class	description
COG34_RS00030	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COG34_RS00040	COG0659	secondary active sulfate transmembrane transporter activity
COG34_RS00055	COG0012	GTP binding
COG34_RS00070	COG3468	outer membrane autotransporter barrel domain protein
COG34_RS00075	COG3284	Transcriptional regulator
COG34_RS00080	COG2376	Dihydroxyacetone kinase
COG34_RS00085	COG1461	Dihydroxyacetone kinase
COG34_RS00090	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
COG34_RS00090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS00090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COG34_RS00115	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
COG34_RS00130	COG1619	proteins homologs of microcin C7 resistance protein MccF
COG34_RS00145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COG34_RS00155	COG2719	SpoVR family
COG34_RS00170	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
COG34_RS00175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COG34_RS00180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COG34_RS00195	COG0179	Fumarylacetoacetate (FAA) hydrolase
COG34_RS00225	COG2894	cell division
COG34_RS00285	COG2200	EAL domain
COG34_RS00310	COG2200	EAL domain
COG34_RS00315	COG0789	Transcriptional regulator
COG34_RS00320	COG5562	phage envelope protein
COG34_RS00330	COG0538	isocitrate dehydrogenase activity
COG34_RS00335	COG1187	pseudouridine synthase activity
COG34_RS00355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COG34_RS00365	COG2205	protein histidine kinase activity
COG34_RS00370	COG2850	peptidyl-arginine hydroxylation
COG34_RS00385	COG3842	ATPase activity
COG34_RS00395	COG1177	transmembrane transport
COG34_RS00400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
COG34_RS00410	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
COG34_RS00415	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
COG34_RS00420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COG34_RS00430	COG4591	ABC-type transport system involved in lipoprotein release permease component
COG34_RS00435	COG1136	(ABC) transporter
COG34_RS00440	COG4591	ABC-type transport system involved in lipoprotein release permease component
COG34_RS00445	COG4763	Acyl-transferase
COG34_RS00450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COG34_RS00455	COG1388	LysM domain
COG34_RS00455	COG1376	ErfK ybiS ycfS ynhG family protein
COG34_RS00465	COG1309	transcriptional regulator
COG34_RS00470	COG3134	Outer membrane lipoprotein
COG34_RS00480	COG1252	NADH dehydrogenase
COG34_RS00505	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
COG34_RS00510	COG5633	Lipoprotein
COG34_RS00515	COG0537	adenosine 5'-monophosphoramidase activity
COG34_RS00520	COG4773	Receptor
COG34_RS00525	COG1263	PTS System
COG34_RS00525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS00530	COG0084	hydrolase, TatD family'
COG34_RS00535	COG0470	DNA polymerase III
COG34_RS00545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
COG34_RS00550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
COG34_RS00555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
COG34_RS00565	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS00570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
COG34_RS00590	COG1399	metal-binding, possibly nucleic acid-binding protein
COG34_RS00595	COG0424	maF-like protein
COG34_RS00600	COG0564	pseudouridine synthase activity
COG34_RS00610	COG1530	ribonuclease E activity
COG34_RS00615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
COG34_RS00620	COG1256	bacterial-type flagellum assembly
COG34_RS00625	COG1705	Flagellar rod assembly protein muramidase FlgJ
COG34_RS00625	COG3951	Flagellar rod assembly protein muramidase FlgJ
COG34_RS00640	COG4786	Flagellar basal body rod
COG34_RS00645	COG4787	bacterial-type flagellum-dependent cell motility
COG34_RS00650	COG1749	Flagellar hook protein flgE
COG34_RS00655	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
COG34_RS00660	COG1558	bacterial-type flagellum-dependent cell motility
COG34_RS00665	COG1815	bacterial-type flagellum-dependent cell motility
COG34_RS00670	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
COG34_RS00675	COG2747	anti-sigma28 factor FlgM
COG34_RS00680	COG3418	PFAM FlgN family protein
COG34_RS00685	COG0728	peptidoglycan biosynthetic process
COG34_RS00690	COG0673	inositol 2-dehydrogenase activity
COG34_RS00700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COG34_RS00710	COG2999	glutathione oxidoreductase activity
COG34_RS00750	COG3038	cytochrome b561
COG34_RS00755	COG2353	YceI-like domain
COG34_RS00765	COG1560	Kdo2-lipid A biosynthetic process
COG34_RS00780	COG5645	(Lipo)protein
COG34_RS00785	COG2943	transferase activity, transferring hexosyl groups
COG34_RS00810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COG34_RS00815	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
COG34_RS00850	COG2197	response regulator
COG34_RS00865	COG1462	curli production assembly transport component CsgG
COG34_RS00875	COG3381	protein complex oligomerization
COG34_RS00910	COG3706	GGDEF domain
COG34_RS00915	COG0457	Tetratricopeptide repeat
COG34_RS00920	COG1649	PFAM Uncharacterised BCR, COG1649
COG34_RS00920	COG0726	polysaccharide deacetylase
COG34_RS00925	COG1215	transferase activity, transferring glycosyl groups
COG34_RS00930	COG3658	cytochrome
COG34_RS00935	COG1702	phosphate starvation-inducible protein PhoH
COG34_RS00950	COG2822	iron ion transport
COG34_RS00970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COG34_RS00985	COG0506	proline dehydrogenase activity
COG34_RS00985	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
COG34_RS00985	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
COG34_RS00990	COG1309	transcriptional regulator
COG34_RS01025	COG2233	PERMEase
COG34_RS01030	COG3729	General stress protein
COG34_RS01075	COG0243	molybdopterin cofactor binding
COG34_RS01080	COG3005	denitrification pathway
COG34_RS01085	COG0745	RESPONSE REGULATOR receiver
COG34_RS01090	COG1879	ABC-type sugar transport system periplasmic component
COG34_RS01095	COG2198	Histidine kinase
COG34_RS01095	COG0784	Response regulator, receiver
COG34_RS01095	COG2205	protein histidine kinase activity
COG34_RS01100	COG0348	domain, Protein
COG34_RS01120	COG1278	Cold shock
COG34_RS01125	COG1278	Cold shock
COG34_RS01145	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COG34_RS01150	COG1596	polysaccharide export
COG34_RS01155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COG34_RS01160	COG3206	protein involved in exopolysaccharide biosynthesis
COG34_RS01160	COG0489	protein tyrosine kinase activity
COG34_RS01175	COG1294	oxidase, subunit
COG34_RS01180	COG1271	oxidase subunit
COG34_RS01185	COG1773	rubredoxin
COG34_RS01190	COG1999	signal sequence binding
COG34_RS01195	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
COG34_RS01200	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
COG34_RS01205	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
COG34_RS01210	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
COG34_RS01220	COG0670	Belongs to the BI1 family
COG34_RS01225	COG2920	part of a sulfur-relay system
COG34_RS01230	COG1254	Belongs to the acylphosphatase family
COG34_RS01245	COG1832	CoA-binding protein
COG34_RS01260	COG0210	DNA helicase
COG34_RS01265	COG3304	Inner membrane component domain
COG34_RS01270	COG1289	transmembrane transporter activity
COG34_RS01275	COG3070	regulator of competence-specific genes
COG34_RS01300	COG1067	ATP-dependent peptidase activity
COG34_RS01310	COG3130	regulation of translation
COG34_RS01315	COG3009	Protein conserved in bacteria
COG34_RS01320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
COG34_RS01320	COG3008	intermembrane lipid transfer
COG34_RS01325	COG2995	paraquat-inducible protein a
COG34_RS01330	COG0488	(ABC) transporter
COG34_RS01340	COG0633	Ferredoxin
COG34_RS01340	COG3217	Mosc domain protein beta barrel domain protein
COG34_RS01355	COG3121	Chaperone
COG34_RS01360	COG3539	Fimbrial protein
COG34_RS01365	COG3539	Fimbrial protein
COG34_RS01370	COG3539	Fimbrial protein
COG34_RS01375	COG3188	usher protein
COG34_RS01380	COG3121	Chaperone
COG34_RS01385	COG3539	Fimbrial protein
COG34_RS01395	COG0431	NADPH-dependent FMN reductase
COG34_RS01400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
COG34_RS01410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
COG34_RS01420	COG0308	aminopeptidase N
COG34_RS01445	COG1448	Aminotransferase
COG34_RS01450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
COG34_RS01455	COG3108	Peptidase M15
COG34_RS01465	COG2989	Protein conserved in bacteria
COG34_RS01475	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
COG34_RS01485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
COG34_RS01495	COG1434	Gram-negative-bacterium-type cell wall biogenesis
COG34_RS01500	COG3173	Aminoglycoside phosphotransferase
COG34_RS01515	COG3214	Protein conserved in bacteria
COG34_RS01525	COG1132	(ABC) transporter
COG34_RS01530	COG0658	competence protein
COG34_RS01530	COG2333	competence protein COMEC
COG34_RS01540	COG0539	negative regulation of cytoplasmic translation
COG34_RS01550	COG0501	Belongs to the peptidase M48B family
COG34_RS01565	COG2323	membrane
COG34_RS01570	COG1944	ATP diphosphatase activity
COG34_RS01575	COG2116	formate transmembrane transporter activity
COG34_RS01580	COG1882	Formate acetyltransferase
COG34_RS01585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COG34_RS01590	COG2249	NAD(P)H dehydrogenase (quinone) activity
COG34_RS01595	COG0583	DNA-binding transcription factor activity
COG34_RS01600	COG0531	amino acid
COG34_RS01610	COG1335	isochorismatase
COG34_RS01615	COG3302	dmso reductase anchor subunit
COG34_RS01620	COG0437	4 iron, 4 sulfur cluster binding
COG34_RS01625	COG0243	molybdopterin cofactor binding
COG34_RS01635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
COG34_RS01650	COG1522	sequence-specific DNA binding
COG34_RS01660	COG0492	ferredoxin-NADP+ reductase activity
COG34_RS01665	COG4988	ABC transporter
COG34_RS01670	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
COG34_RS01690	COG0542	response to heat
COG34_RS01700	COG1278	Cold shock
COG34_RS01705	COG0577	efflux transmembrane transporter activity
COG34_RS01705	COG1136	(ABC) transporter
COG34_RS01710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COG34_RS01715	COG2990	Protein conserved in bacteria
COG34_RS01720	COG3593	DNA synthesis involved in DNA repair
COG34_RS01735	COG2431	L-lysine efflux transmembrane transporter activity
COG34_RS01745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
COG34_RS01750	COG0028	Belongs to the TPP enzyme family
COG34_RS01755	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
COG34_RS01760	COG0702	epimerase
COG34_RS01765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
COG34_RS01770	COG3023	N-Acetylmuramoyl-L-alanine amidase
COG34_RS01785	COG1126	abc transporter atp-binding protein
COG34_RS01790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
COG34_RS01795	COG4215	(ABC) transporter
COG34_RS01800	COG4160	amino acid transport
COG34_RS01805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
COG34_RS01820	COG1177	transmembrane transport
COG34_RS01825	COG1176	ABC-type spermidine putrescine transport system, permease component I
COG34_RS01830	COG3842	ATPase activity
COG34_RS01835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
COG34_RS01855	COG0778	Nitroreductase
COG34_RS01865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
COG34_RS01880	COG3226	Transcriptional regulator
COG34_RS01885	COG0738	Major facilitator superfamily
COG34_RS01890	COG0561	phosphatase activity
COG34_RS01900	COG2814	Major facilitator Superfamily
COG34_RS01905	COG0671	phosphoesterase, PA-phosphatase related
COG34_RS01910	COG1349	DNA-binding transcription factor activity
COG34_RS01915	COG1686	Belongs to the peptidase S11 family
COG34_RS01920	COG0625	glutathione transferase activity
COG34_RS01925	COG2133	pyrroloquinoline quinone binding
COG34_RS01940	COG2199	diguanylate cyclase activity
COG34_RS01945	COG2200	EAL domain
COG34_RS01970	COG1446	asparaginase
COG34_RS01975	COG0303	'Molybdopterin
COG34_RS01980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
COG34_RS01985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COG34_RS01990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COG34_RS01995	COG1882	Formate acetyltransferase
COG34_RS02000	COG0561	phosphatase activity
COG34_RS02010	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS02020	COG0488	(ABC) transporter
COG34_RS02025	COG1376	ErfK ybiS ycfS ynhG family protein
COG34_RS02030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
COG34_RS02035	COG1321	iron dependent repressor
COG34_RS02045	COG2194	sulfuric ester hydrolase activity
COG34_RS02050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
COG34_RS02055	COG5006	permease, DMT superfamily
COG34_RS02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
COG34_RS02085	COG0765	amino acid transport
COG34_RS02090	COG1126	abc transporter atp-binding protein
COG34_RS02095	COG0668	transmembrane transport
COG34_RS02110	COG4774	siderophore transport
COG34_RS02120	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
COG34_RS02130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
COG34_RS02135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COG34_RS02140	COG1199	ATP-dependent helicase activity
COG34_RS02150	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
COG34_RS02155	COG0513	Belongs to the DEAD box helicase family
COG34_RS02160	COG1309	transcriptional regulator
COG34_RS02170	COG1131	(ABC) transporter
COG34_RS02175	COG0842	Transport permease protein
COG34_RS02180	COG0842	Transport permease protein
COG34_RS02190	COG3568	Endonuclease Exonuclease Phosphatase
COG34_RS02195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COG34_RS02200	COG0392	lysyltransferase activity
COG34_RS02205	COG0670	Belongs to the BI1 family
COG34_RS02215	COG0670	Belongs to the BI1 family
COG34_RS02220	COG0314	molybdopterin synthase activity
COG34_RS02225	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
COG34_RS02235	COG0521	Mo-molybdopterin cofactor biosynthetic process
COG34_RS02245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
COG34_RS02255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
COG34_RS02260	COG2226	methyltransferase
COG34_RS02275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
COG34_RS02280	COG1881	PFAM PEBP family protein
COG34_RS02290	COG2199	diguanylate cyclase activity
COG34_RS02295	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
COG34_RS02300	COG5301	cellulose 1,4-beta-cellobiosidase activity
COG34_RS02335	COG1196	nuclear chromosome segregation
COG34_RS02385	COG1030	water channel activity
COG34_RS02405	COG4220	transposase activity
COG34_RS02430	COG3772	lysozyme
COG34_RS02490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
COG34_RS02495	COG2076	Multidrug Resistance protein
COG34_RS02610	COG0582	viral genome integration into host DNA
COG34_RS02615	COG4677	pectinesterase activity
COG34_RS02620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
COG34_RS02625	COG0471	metal ion transport
COG34_RS02630	COG2828	Protein conserved in bacteria
COG34_RS02635	COG0583	DNA-binding transcription factor activity
COG34_RS02645	COG0561	phosphatase activity
COG34_RS02655	COG4149	molybdate abc transporter
COG34_RS02660	COG0725	ABC transporter, periplasmic molybdate-binding protein
COG34_RS02675	COG3585	molybdate ion transport
COG34_RS02675	COG2005	Transcriptional regulator
COG34_RS02680	COG1119	ATPase activity
COG34_RS02685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
COG34_RS02690	COG1085	galactose-1-phosphate uridylyltransferase
COG34_RS02700	COG2017	converts alpha-aldose to the beta-anomer
COG34_RS02710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
COG34_RS02725	COG1230	cation diffusion facilitator family transporter
COG34_RS02730	COG3201	nicotinamide mononucleotide transporter
COG34_RS02780	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
COG34_RS02785	COG2885	chlorophyll binding
COG34_RS02795	COG3064	Membrane
COG34_RS02800	COG0848	biopolymer transport protein
COG34_RS02805	COG0811	peptide transport
COG34_RS02810	COG0824	Thioesterase
COG34_RS02815	COG3790	cyd operon protein YbgE
COG34_RS02820	COG4890	Cyd operon protein YbgT
COG34_RS02825	COG1294	oxidase, subunit
COG34_RS02830	COG1271	oxidase subunit
COG34_RS02840	COG0383	alpha-mannosidase activity
COG34_RS02845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS02845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS02845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS02850	COG2188	Transcriptional regulator
COG34_RS02855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
COG34_RS02865	COG0508	dehydrogenase complex catalyzes the overall conversion of
COG34_RS02870	COG0567	Dehydrogenase, E1 component
COG34_RS02875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
COG34_RS02880	COG1053	succinate dehydrogenase
COG34_RS02885	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
COG34_RS02890	COG2009	succinate dehydrogenase
COG34_RS02905	COG0372	Belongs to the citrate synthase family
COG34_RS02910	COG3539	Fimbrial protein
COG34_RS02915	COG3188	usher protein
COG34_RS02920	COG3121	Chaperone
COG34_RS02925	COG3539	Fimbrial protein
COG34_RS02930	COG3180	Ammonia monooxygenase
COG34_RS02945	COG1984	allophanate hydrolase subunit 2
COG34_RS02950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
COG34_RS02955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COG34_RS02965	COG0415	Belongs to the DNA photolyase family
COG34_RS02970	COG3272	Protein of unknown function (DUF1722)
COG34_RS03000	COG3209	COG3209 Rhs family protein
COG34_RS03030	COG2205	protein histidine kinase activity
COG34_RS03035	COG0745	RESPONSE REGULATOR receiver
COG34_RS03045	COG1982	Orn Lys Arg decarboxylase major
COG34_RS03050	COG0531	amino acid
COG34_RS03055	COG0033	Phosphoglucomutase
COG34_RS03060	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
COG34_RS03065	COG0596	Alpha beta hydrolase
COG34_RS03075	COG0716	FMN binding
COG34_RS03085	COG0735	belongs to the Fur family
COG34_RS03110	COG1263	PTS System
COG34_RS03110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS03110	COG2190	(PTS) system
COG34_RS03120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
COG34_RS03125	COG1940	carbohydrate kinase activity
COG34_RS03125	COG1846	Transcriptional regulator
COG34_RS03130	COG0647	UMP catabolic process
COG34_RS03140	COG0367	asparagine synthase
COG34_RS03185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
COG34_RS03195	COG1702	phosphate starvation-inducible protein PhoH
COG34_RS03205	COG4535	Mg2 and Co2 transporter CorC
COG34_RS03210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
COG34_RS03225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
COG34_RS03230	COG0765	amino acid transport
COG34_RS03235	COG0765	amino acid transport
COG34_RS03240	COG1126	abc transporter atp-binding protein
COG34_RS03250	COG0443	Heat shock 70 kDa protein
COG34_RS03255	COG2214	Heat shock protein DnaJ domain protein
COG34_RS03265	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
COG34_RS03270	COG2214	Heat shock protein DnaJ domain protein
COG34_RS03280	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
COG34_RS03285	COG2888	peptidyl-tyrosine sulfation
COG34_RS03300	COG1466	dna polymerase III delta subunit
COG34_RS03310	COG0406	alpha-ribazole phosphatase activity
COG34_RS03315	COG0799	negative regulation of ribosome biogenesis
COG34_RS03325	COG0768	penicillin binding
COG34_RS03330	COG0772	Belongs to the SEDS family
COG34_RS03335	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
COG34_RS03340	COG1686	Belongs to the peptidase S11 family
COG34_RS03360	COG0583	DNA-binding transcription factor activity
COG34_RS03375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
COG34_RS03380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
COG34_RS03405	COG3069	C4-dicarboxylate transmembrane transporter activity
COG34_RS03410	COG4565	transcriptional regulatory protein
COG34_RS03415	COG3290	protein histidine kinase activity
COG34_RS03420	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
COG34_RS03430	COG2301	Belongs to the HpcH HpaI aldolase family
COG34_RS03435	COG3051	citrate lyase alpha subunit
COG34_RS03450	COG0471	metal ion transport
COG34_RS03455	COG3719	Belongs to the RNase T2 family
COG34_RS03465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
COG34_RS03475	COG1063	alcohol dehydrogenase
COG34_RS03480	COG0589	response to stress
COG34_RS03485	COG3634	alkyl hydroperoxide reductase activity
COG34_RS03495	COG0450	alkyl hydroperoxide reductase
COG34_RS03500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
COG34_RS03505	COG0583	DNA-binding transcription factor activity
COG34_RS03510	COG3969	phosphoadenosine phosphosulfate
COG34_RS03515	COG1475	DNA binding
COG34_RS03520	COG0436	Aminotransferase
COG34_RS03525	COG0371	Dehydrogenase
COG34_RS03530	COG2879	small protein
COG34_RS03535	COG1966	Carbon starvation protein
COG34_RS03540	COG2050	protein possibly involved in aromatic compounds catabolism
COG34_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS03550	COG1535	isochorismatase
COG34_RS03550	COG3433	isochorismatase activity
COG34_RS03555	COG1021	2,3-dihydroxybenzoate-AMP ligase
COG34_RS03560	COG1169	isochorismate synthase
COG34_RS03570	COG4592	Periplasmic binding protein
COG34_RS03580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COG34_RS03585	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COG34_RS03590	COG1120	ATPase activity
COG34_RS03595	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
COG34_RS03600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
COG34_RS03600	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
COG34_RS03605	COG3251	PFAM MbtH domain protein
COG34_RS03610	COG2382	esterase
COG34_RS03620	COG4771	TonB-dependent receptor
COG34_RS03625	COG2977	Belongs to the P-Pant transferase superfamily
COG34_RS03655	COG2315	Protein conserved in bacteria
COG34_RS03660	COG0778	Nitroreductase
COG34_RS03665	COG0668	transmembrane transport
COG34_RS03670	COG1113	amino acid transport
COG34_RS03675	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COG34_RS03680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COG34_RS03685	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COG34_RS03690	COG1538	Outer membrane efflux protein
COG34_RS03700	COG0745	RESPONSE REGULATOR receiver
COG34_RS03705	COG5002	protein histidine kinase activity
COG34_RS03725	COG4104	PAAR repeat-containing protein
COG34_RS03725	COG3209	COG3209 Rhs family protein
COG34_RS03745	COG1215	transferase activity, transferring glycosyl groups
COG34_RS03765	COG2207	Transcriptional regulator
COG34_RS03780	COG2197	response regulator
COG34_RS03785	COG3539	Fimbrial protein
COG34_RS03790	COG3539	Fimbrial protein
COG34_RS03795	COG3188	usher protein
COG34_RS03800	COG3121	Chaperone
COG34_RS03805	COG3539	Fimbrial protein
COG34_RS03815	COG2501	S4 domain
COG34_RS03820	COG1988	membrane-bound metal-dependent
COG34_RS03830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COG34_RS03845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COG34_RS03850	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COG34_RS03855	COG0549	Belongs to the carbamate kinase family
COG34_RS03865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
COG34_RS03870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
COG34_RS03875	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
COG34_RS03880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
COG34_RS03885	COG3257	ureidoglycine aminohydrolase activity
COG34_RS03890	COG1929	Belongs to the glycerate kinase type-1 family
COG34_RS03895	COG2233	PERMEase
COG34_RS03905	COG1953	Uracil, thiamine, allantoin
COG34_RS03910	COG2084	Dehydrogenase
COG34_RS03915	COG3622	Belongs to the hyi family
COG34_RS03920	COG3960	tartronate-semialdehyde synthase activity
COG34_RS03925	COG1414	Transcriptional regulator
COG34_RS03935	COG0583	DNA-binding transcription factor activity
COG34_RS03945	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
COG34_RS03950	COG4181	ATPase activity
COG34_RS03955	COG2755	lipolytic protein G-D-S-L family
COG34_RS03960	COG0300	oxidoreductase activity
COG34_RS03965	COG3118	belongs to the thioredoxin family
COG34_RS03970	COG0390	transport system, permease component
COG34_RS03975	COG4619	ABC transporter
COG34_RS03980	COG0330	HflC and HflK could
COG34_RS03985	COG1585	Membrane protein implicated in regulation of membrane protease activity
COG34_RS03990	COG0789	Transcriptional regulator
COG34_RS03995	COG0531	amino acid
COG34_RS04000	COG2066	Belongs to the glutaminase family
COG34_RS04005	COG2217	Heavy metal translocating P-type atpase
COG34_RS04010	COG3093	addiction module antidote protein HigA
COG34_RS04020	COG3735	TraB family
COG34_RS04030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COG34_RS04035	COG0737	Belongs to the 5'-nucleotidase family
COG34_RS04045	COG2223	nitrite transmembrane transporter activity
COG34_RS04050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
COG34_RS04050	COG4651	solute:proton antiporter activity
COG34_RS04055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COG34_RS04095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COG34_RS04110	COG2832	Protein of unknown function (DUF454)
COG34_RS04115	COG3923	Primosomal replication protein n
COG34_RS04125	COG1196	nuclear chromosome segregation
COG34_RS04125	COG3264	Mechanosensitive ion channel
COG34_RS04135	COG1309	transcriptional regulator
COG34_RS04140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COG34_RS04145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COG34_RS04160	COG0110	maltose O-acetyltransferase activity
COG34_RS04170	COG4943	cyclic-guanylate-specific phosphodiesterase activity
COG34_RS04175	COG5507	3-demethylubiquinone-9 3-methyltransferase
COG34_RS04185	COG3695	enzyme binding
COG34_RS04190	COG3126	Type III secretion system lipoprotein chaperone (YscW)
COG34_RS04195	COG1946	Acyl-CoA thioesterase
COG34_RS04200	COG0004	ammonium transporteR
COG34_RS04205	COG0347	Belongs to the P(II) protein family
COG34_RS04210	COG1132	(ABC) transporter
COG34_RS04215	COG1132	(ABC) transporter
COG34_RS04220	COG1522	sequence-specific DNA binding
COG34_RS04230	COG4533	DNA binding
COG34_RS04240	COG0824	Thioesterase
COG34_RS04245	COG1555	photosystem II stabilization
COG34_RS04250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
COG34_RS04255	COG0776	regulation of translation
COG34_RS04260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
COG34_RS04285	COG0271	Belongs to the BolA IbaG family
COG34_RS04290	COG3056	Lipoprotein
COG34_RS04295	COG2223	nitrite transmembrane transporter activity
COG34_RS04300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
COG34_RS04305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
COG34_RS04310	COG1845	cytochrome c oxidase, subunit III
COG34_RS04315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
COG34_RS04340	COG2814	Major facilitator Superfamily
COG34_RS04350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COG34_RS04355	COG0693	protein deglycase activity
COG34_RS04370	COG0142	geranyltranstransferase activity
COG34_RS04380	COG0667	Aldo Keto reductase
COG34_RS04385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
COG34_RS04390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
COG34_RS04405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COG34_RS04405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COG34_RS04415	COG4238	major outer membrane lipoprotein
COG34_RS04425	COG3248	Nucleoside-binding outer membrane protein
COG34_RS04430	COG1403	HNH endonuclease
COG34_RS04435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
COG34_RS04440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
COG34_RS04445	COG1862	Preprotein translocase
COG34_RS04465	COG0366	Alpha amylase catalytic
COG34_RS04470	COG1113	amino acid transport
COG34_RS04475	COG1114	Component of the transport system for branched-chain amino acids
COG34_RS04480	COG5002	protein histidine kinase activity
COG34_RS04485	COG0745	RESPONSE REGULATOR receiver
COG34_RS04490	COG0420	3'-5' exonuclease activity
COG34_RS04495	COG0419	ATPase involved in DNA repair
COG34_RS04500	COG2814	Major facilitator Superfamily
COG34_RS04505	COG1940	carbohydrate kinase activity
COG34_RS04525	COG4126	flavin adenine dinucleotide binding
COG34_RS04550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COG34_RS04555	COG3706	GGDEF domain
COG34_RS04565	COG1785	Belongs to the alkaline phosphatase family
COG34_RS04580	COG1181	Belongs to the D-alanine--D-alanine ligase family
COG34_RS04600	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
COG34_RS04610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
COG34_RS04615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
COG34_RS04640	COG0113	porphobilinogen synthase activity
COG34_RS04645	COG2175	clavaminate synthase activity
COG34_RS04650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
COG34_RS04660	COG4521	taurine ABC transporter
COG34_RS04670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
COG34_RS04675	COG1215	transferase activity, transferring glycosyl groups
COG34_RS04705	COG3122	Protein conserved in bacteria
COG34_RS04710	COG2814	Major facilitator Superfamily
COG34_RS04745	COG1414	Transcriptional regulator
COG34_RS04750	COG1609	Transcriptional regulator
COG34_RS04760	COG3250	beta-galactosidase activity
COG34_RS04765	COG2223	nitrite transmembrane transporter activity
COG34_RS04770	COG0110	maltose O-acetyltransferase activity
COG34_RS04775	COG2807	transmembrane transport
COG34_RS04785	COG0288	reversible hydration of carbon dioxide
COG34_RS04790	COG0583	DNA-binding transcription factor activity
COG34_RS04795	COG0402	S-adenosylhomocysteine deaminase activity
COG34_RS04800	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
COG34_RS04805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
COG34_RS04810	COG2079	MmgE PrpD family protein
COG34_RS04815	COG0372	Belongs to the citrate synthase family
COG34_RS04820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
COG34_RS04825	COG3829	transcription factor binding
COG34_RS04835	COG1280	lysine exporter protein (LysE YggA)
COG34_RS04850	COG1064	alcohol dehydrogenase
COG34_RS04860	COG1172	Belongs to the binding-protein-dependent transport system permease family
COG34_RS04865	COG1129	ABC transporter
COG34_RS04870	COG1879	ABC-type sugar transport system periplasmic component
COG34_RS04880	COG0402	S-adenosylhomocysteine deaminase activity
COG34_RS04885	COG0549	Belongs to the carbamate kinase family
COG34_RS04890	COG1304	FMN binding
COG34_RS04895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
COG34_RS04905	COG0666	response to abiotic stimulus
COG34_RS04920	COG0583	DNA-binding transcription factor activity
COG34_RS04925	COG2771	luxR family
COG34_RS04925	COG2200	EAL domain
COG34_RS04935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
COG34_RS04965	COG0582	viral genome integration into host DNA
COG34_RS04970	COG2771	luxR family
COG34_RS04970	COG2200	EAL domain
COG34_RS04985	COG3468	outer membrane autotransporter barrel domain protein
COG34_RS05005	COG1556	Lactate utilization protein
COG34_RS05010	COG1139	Iron-sulfur cluster binding protein
COG34_RS05015	COG0247	lactate metabolic process
COG34_RS05020	COG2207	Transcriptional regulator
COG34_RS05025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COG34_RS05035	COG3059	membrane
COG34_RS05040	COG0656	L-ascorbic acid biosynthetic process
COG34_RS05045	COG3708	Transcriptional regulator
COG34_RS05045	COG2207	Transcriptional regulator
COG34_RS05050	COG1388	LysM domain
COG34_RS05105	COG3188	usher protein
COG34_RS05115	COG3121	Chaperone
COG34_RS05120	COG0727	PFAM Uncharacterised protein family (UPF0153)
COG34_RS05130	COG3477	response to acidic pH
COG34_RS05140	COG2080	2 iron, 2 sulfur cluster binding
COG34_RS05145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
COG34_RS05150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
COG34_RS05155	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
COG34_RS05160	COG0583	DNA-binding transcription factor activity
COG34_RS05255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
COG34_RS05280	COG3778	Protein conserved in bacteria
COG34_RS05285	COG3299	homolog of phage Mu protein gp47
COG34_RS05335	COG4386	tail sheath protein
COG34_RS05380	COG4695	Portal protein
COG34_RS05390	COG1802	Transcriptional regulator
COG34_RS05390	COG4626	Terminase
COG34_RS05425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
COG34_RS05440	COG1403	HNH endonuclease
COG34_RS05450	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
COG34_RS05460	COG4725	Belongs to the MT-A70-like family
COG34_RS05470	COG1846	Transcriptional regulator
COG34_RS05485	COG4197	protein conserved in bacteria, prophage-related
COG34_RS05490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COG34_RS05515	COG5532	Uncharacterized conserved protein (DUF2303)
COG34_RS05520	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
COG34_RS05545	COG0582	viral genome integration into host DNA
COG34_RS05565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
COG34_RS05585	COG2195	Cleaves the N-terminal amino acid of tripeptides
COG34_RS05590	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COG34_RS05595	COG1690	Belongs to the RtcB family
COG34_RS05605	COG0454	-acetyltransferase
COG34_RS05635	COG0791	NLP P60 protein
COG34_RS05640	COG3077	Addiction module antitoxin, RelB DinJ family
COG34_RS05645	COG3041	Addiction module toxin RelE StbE family
COG34_RS05650	COG3034	peptidoglycan biosynthetic process
COG34_RS05655	COG0121	glutamine amidotransferase
COG34_RS05665	COG1960	acyl-CoA dehydrogenase activity
COG34_RS05675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
COG34_RS05805	COG3157	Type VI secretion system effector, Hcp
COG34_RS05810	COG4104	PAAR repeat-containing protein
COG34_RS05835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
COG34_RS05845	COG2226	methyltransferase
COG34_RS05855	COG0741	lytic transglycosylase activity
COG34_RS05855	COG1388	LysM domain
COG34_RS05860	COG2226	methyltransferase
COG34_RS05870	COG0583	DNA-binding transcription factor activity
COG34_RS05875	COG0656	L-ascorbic acid biosynthetic process
COG34_RS05910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
COG34_RS05915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COG34_RS05920	COG2011	ABC-type metal ion transport system permease component
COG34_RS05925	COG1464	Belongs to the NlpA lipoprotein family
COG34_RS05935	COG1720	tRNA m6t6A37 methyltransferase activity
COG34_RS05950	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS05960	COG3015	lipoprotein NlpE involved in copper resistance
COG34_RS05965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COG34_RS05970	COG4681	YaeQ
COG34_RS05980	COG4568	rho-dependent transcription termination
COG34_RS05990	COG0346	lactoylglutathione lyase activity
COG34_RS05995	COG1982	Orn Lys Arg decarboxylase major
COG34_RS06005	COG0587	DNA-directed DNA polymerase activity
COG34_RS06030	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
COG34_RS06035	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
COG34_RS06045	COG0750	zinc metalloprotease
COG34_RS06050	COG0575	Belongs to the CDS family
COG34_RS06055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COG34_RS06060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
COG34_RS06095	COG0024	Methionine aminopeptidase
COG34_RS06115	COG3835	regulator
COG34_RS06120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COG34_RS06140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
COG34_RS06145	COG2860	membrane
COG34_RS06165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COG34_RS06170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
COG34_RS06175	COG1120	ATPase activity
COG34_RS06180	COG4774	siderophore transport
COG34_RS06185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
COG34_RS06195	COG1643	Atp-dependent helicase
COG34_RS06200	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
COG34_RS06210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
COG34_RS06220	COG0617	tRNA 3'-terminal CCA addition
COG34_RS06225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
COG34_RS06230	COG3539	Fimbrial protein
COG34_RS06235	COG3121	Chaperone
COG34_RS06240	COG3188	usher protein
COG34_RS06245	COG3539	Fimbrial protein
COG34_RS06250	COG3539	Fimbrial protein
COG34_RS06255	COG3539	Fimbrial protein
COG34_RS06260	COG3539	Fimbrial protein
COG34_RS06275	COG5464	transposase or invertase
COG34_RS06295	COG0726	polysaccharide deacetylase
COG34_RS06300	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS06305	COG0842	Transport permease protein
COG34_RS06310	COG1131	(ABC) transporter
COG34_RS06315	COG0288	reversible hydration of carbon dioxide
COG34_RS06320	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
COG34_RS06325	COG4993	Dehydrogenase
COG34_RS06330	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS06340	COG2132	Multicopper oxidase
COG34_RS06365	COG1049	propionate catabolic process, 2-methylcitrate cycle
COG34_RS06375	COG3064	Membrane
COG34_RS06380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COG34_RS06385	COG0508	dehydrogenase complex catalyzes the overall conversion of
COG34_RS06390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
COG34_RS06400	COG2186	Transcriptional regulator
COG34_RS06405	COG1113	amino acid transport
COG34_RS06410	COG3725	Membrane protein required for beta-lactamase induction
COG34_RS06415	COG3023	N-Acetylmuramoyl-L-alanine amidase
COG34_RS06420	COG0157	Belongs to the NadC ModD family
COG34_RS06430	COG4969	Belongs to the N-Me-Phe pilin family
COG34_RS06435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
COG34_RS06440	COG1459	type II secretion system
COG34_RS06450	COG0237	dephospho-CoA kinase activity
COG34_RS06465	COG0494	nUDIX hydrolase
COG34_RS06485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COG34_RS06490	COG0849	cell division
COG34_RS06495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
COG34_RS06500	COG1181	Belongs to the D-alanine--D-alanine ligase family
COG34_RS06515	COG0772	Belongs to the SEDS family
COG34_RS06530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
COG34_RS06535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COG34_RS06540	COG0768	penicillin binding
COG34_RS06545	COG3116	cell division
COG34_RS06570	COG1609	Transcriptional regulator
COG34_RS06580	COG0440	acetolactate synthase activity
COG34_RS06585	COG0028	Belongs to the TPP enzyme family
COG34_RS06590	COG0583	DNA-binding transcription factor activity
COG34_RS06605	COG0473	3-isopropylmalate dehydrogenase activity
COG34_RS06620	COG2814	Major facilitator Superfamily
COG34_RS06635	COG4143	(ABC) transporter
COG34_RS06640	COG1178	ABC-type Fe3 transport system permease component
COG34_RS06650	COG0586	Pfam SNARE associated Golgi protein
COG34_RS06655	COG4977	sequence-specific DNA binding
COG34_RS06675	COG0235	Class ii aldolase
COG34_RS06680	COG0417	DNA replication proofreading
COG34_RS06690	COG0564	pseudouridine synthase activity
COG34_RS06695	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
COG34_RS06700	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
COG34_RS06705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
COG34_RS06730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COG34_RS06745	COG2271	Major facilitator Superfamily
COG34_RS06750	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
COG34_RS06755	COG0644	oxidoreductase
COG34_RS06810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
COG34_RS06815	COG0505	Belongs to the CarA family
COG34_RS06840	COG1047	Peptidyl-prolyl cis-trans
COG34_RS06855	COG0196	riboflavin kinase activity
COG34_RS06890	COG0583	DNA-binding transcription factor activity
COG34_RS06920	COG4735	regulation of single-species biofilm formation
COG34_RS06925	COG1584	GPR1 FUN34 yaaH family protein
COG34_RS06930	COG0521	Mo-molybdopterin cofactor biosynthetic process
COG34_RS06935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COG34_RS06940	COG1115	amino acid carrier protein
COG34_RS06950	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS06965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
COG34_RS06975	COG0527	aspartate kinase activity
COG34_RS06975	COG0460	homoserine dehydrogenase
COG34_RS06985	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
COG34_RS06995	COG0745	RESPONSE REGULATOR receiver
COG34_RS07000	COG4452	Inner membrane protein CreD
COG34_RS07005	COG2205	protein histidine kinase activity
COG34_RS07010	COG0745	RESPONSE REGULATOR receiver
COG34_RS07015	COG3045	CreA protein
COG34_RS07020	COG3708	Transcriptional regulator
COG34_RS07020	COG2207	Transcriptional regulator
COG34_RS07040	COG0741	lytic transglycosylase activity
COG34_RS07050	COG0488	(ABC) transporter
COG34_RS07055	COG1056	cytidyltransferase-related domain
COG34_RS07055	COG3172	ATPase kinase involved in NAD metabolism
COG34_RS07060	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COG34_RS07065	COG0560	Phosphoserine phosphatase
COG34_RS07070	COG3726	membrane protein affecting hemolysin expression
COG34_RS07105	COG1328	CTP reductase activity
COG34_RS07110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COG34_RS07115	COG0084	hydrolase, TatD family'
COG34_RS07120	COG4667	esterase of the alpha-beta hydrolase superfamily
COG34_RS07130	COG2823	Periplasmic or secreted lipoprotein
COG34_RS07140	COG1011	Hydrolase
COG34_RS07145	COG0456	acetyltransferase
COG34_RS07150	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
COG34_RS07180	COG4114	ferric iron reductase
COG34_RS07185	COG2197	response regulator
COG34_RS07190	COG2197	response regulator
COG34_RS07195	COG2966	Psort location CytoplasmicMembrane, score
COG34_RS07210	COG1484	DNA-dependent DNA replication
COG34_RS07225	COG1063	alcohol dehydrogenase
COG34_RS07230	COG1802	Transcriptional regulator
COG34_RS07235	COG2271	Major facilitator Superfamily
COG34_RS07240	COG0840	transmembrane signaling receptor activity
COG34_RS07250	COG1966	Carbon starvation protein
COG34_RS07255	COG2879	small protein
COG34_RS07260	COG0523	cobalamin synthesis protein
COG34_RS07275	COG1715	Restriction endonuclease
COG34_RS07280	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
COG34_RS07285	COG0732	type I restriction modification DNA specificity domain
COG34_RS07290	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
COG34_RS07300	COG5457	Domain of unknown function (DUF1127)
COG34_RS07305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
COG34_RS07325	COG2814	Major facilitator Superfamily
COG34_RS07335	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
COG34_RS07340	COG1924	4 iron, 4 sulfur cluster binding
COG34_RS07355	COG0477	Major facilitator Superfamily
COG34_RS07365	COG3366	ferrous iron transmembrane transporter activity
COG34_RS07370	COG0700	Nucleoside recognition
COG34_RS07375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
COG34_RS07380	COG0583	DNA-binding transcription factor activity
COG34_RS07400	COG2186	Transcriptional regulator
COG34_RS07410	COG0246	Mannitol dehydrogenase
COG34_RS07425	COG2610	gluconate transmembrane transporter activity
COG34_RS07465	COG3436	PFAM IS66 Orf2 family protein
COG34_RS07470	COG4372	Transposase
COG34_RS07510	COG1595	DNA-templated transcription, initiation
COG34_RS07515	COG3712	iron ion homeostasis
COG34_RS07520	COG4772	TonB-dependent receptor
COG34_RS07525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
COG34_RS07530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COG34_RS07535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COG34_RS07540	COG1120	ATPase activity
COG34_RS07545	COG2085	NADP oxidoreductase coenzyme F420-dependent
COG34_RS07555	COG3344	reverse transcriptase
COG34_RS07570	COG0726	polysaccharide deacetylase
COG34_RS07575	COG0297	glycogen (starch) synthase activity
COG34_RS07580	COG2990	Protein conserved in bacteria
COG34_RS07595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
COG34_RS07620	COG0604	alcohol dehydrogenase
COG34_RS07640	COG0440	acetolactate synthase activity
COG34_RS07660	COG3177	Filamentation induced by cAMP protein fic
COG34_RS07675	COG3335	DDE superfamily endonuclease
COG34_RS07690	COG2205	protein histidine kinase activity
COG34_RS07710	COG4227	nucleotidyltransferase activity
COG34_RS07730	COG1064	alcohol dehydrogenase
COG34_RS07735	COG3265	gluconokinase activity
COG34_RS07740	COG1063	alcohol dehydrogenase
COG34_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS07750	COG2610	gluconate transmembrane transporter activity
COG34_RS07755	COG1609	Transcriptional regulator
COG34_RS07760	COG0433	COG0433 Predicted ATPase
COG34_RS07765	COG0795	lipopolysaccharide-transporting ATPase activity
COG34_RS07770	COG0795	lipopolysaccharide-transporting ATPase activity
COG34_RS07780	COG2927	DNA polymerase III (CHI subunit)
COG34_RS07785	COG0525	valine-tRNA ligase activity
COG34_RS07790	COG4269	membrane
COG34_RS07795	COG0456	acetyltransferase
COG34_RS07800	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
COG34_RS07835	COG2731	YhcH YjgK YiaL family protein
COG34_RS07840	COG1309	transcriptional regulator
COG34_RS07845	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS07850	COG0251	oxidation-reduction process
COG34_RS07875	COG0251	oxidation-reduction process
COG34_RS07885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
COG34_RS07895	COG1609	Transcriptional regulator
COG34_RS07900	COG1263	PTS System
COG34_RS07900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS07905	COG0366	Alpha amylase catalytic
COG34_RS07910	COG1328	CTP reductase activity
COG34_RS07915	COG0602	queuosine metabolic process
COG34_RS07920	COG3783	Cytochrome b(562)
COG34_RS07925	COG0312	modulator of DNA gyrase
COG34_RS07935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
COG34_RS07945	COG1172	Belongs to the binding-protein-dependent transport system permease family
COG34_RS07950	COG1172	Belongs to the binding-protein-dependent transport system permease family
COG34_RS07955	COG1129	ABC transporter
COG34_RS07965	COG1879	ABC-type sugar transport system periplasmic component
COG34_RS07970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
COG34_RS07975	COG2337	Toxic component of a toxin-antitoxin (TA) module
COG34_RS07980	COG2336	PFAM SpoVT AbrB
COG34_RS07985	COG2105	PFAM AIG2 family protein
COG34_RS07990	COG2911	Protein conserved in bacteria
COG34_RS07995	COG0729	surface antigen
COG34_RS08010	COG1253	flavin adenine dinucleotide binding
COG34_RS08020	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
COG34_RS08025	COG1218	3'(2'),5'-bisphosphate nucleotidase
COG34_RS08030	COG0737	Belongs to the 5'-nucleotidase family
COG34_RS08035	COG1733	regulation of RNA biosynthetic process
COG34_RS08040	COG0702	epimerase
COG34_RS08045	COG0697	spore germination
COG34_RS08055	COG1113	amino acid transport
COG34_RS08060	COG0545	Peptidyl-prolyl cis-trans isomerase
COG34_RS08065	COG3061	Opacity-associated protein A
COG34_RS08070	COG1309	transcriptional regulator
COG34_RS08085	COG1024	Enoyl-CoA hydratase
COG34_RS08090	COG4670	ketone body catabolic process
COG34_RS08095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
COG34_RS08110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
COG34_RS08120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COG34_RS08155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS08160	COG3414	Phosphotransferase system galactitol-specific IIB component
COG34_RS08165	COG3037	sugar-specific permease SgaT UlaA
COG34_RS08180	COG1073	alpha beta
COG34_RS08185	COG3650	response to hydrogen peroxide
COG34_RS08195	COG1960	acyl-CoA dehydrogenase activity
COG34_RS08200	COG0754	glutathionylspermidine amidase activity
COG34_RS08205	COG5463	Belongs to the UPF0441 family
COG34_RS08210	COG3766	membrane
COG34_RS08220	COG1842	Phage shock protein A
COG34_RS08225	COG3789	protein conserved in bacteria
COG34_RS08235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COG34_RS08240	COG0557	exoribonuclease II activity
COG34_RS08255	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
COG34_RS08260	COG0330	HflC and HflK could
COG34_RS08265	COG0330	HflC and HflK could
COG34_RS08270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COG34_RS08290	COG0860	N-Acetylmuramoyl-L-alanine amidase
COG34_RS08295	COG0802	atpase or kinase
COG34_RS08300	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COG34_RS08300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
COG34_RS08305	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
COG34_RS08345	COG3264	Mechanosensitive ion channel
COG34_RS08345	COG1511	domain protein
COG34_RS08350	COG0531	amino acid
COG34_RS08360	COG1053	succinate dehydrogenase
COG34_RS08365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
COG34_RS08380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
COG34_RS08385	COG3040	lipid binding
COG34_RS08390	COG2076	Multidrug Resistance protein
COG34_RS08395	COG5510	response to toxic substance
COG34_RS08400	COG5510	response to toxic substance
COG34_RS08410	COG1509	lysine 2,3-aminomutase activity
COG34_RS08420	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS08445	COG0531	amino acid
COG34_RS08450	COG3030	protein affecting phage T7 exclusion by the F plasmid
COG34_RS08455	COG1027	Aspartate ammonia-lyase
COG34_RS08460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
COG34_RS08475	COG1309	transcriptional regulator
COG34_RS08485	COG0582	viral genome integration into host DNA
COG34_RS08495	COG2194	sulfuric ester hydrolase activity
COG34_RS08535	COG0582	viral genome integration into host DNA
COG34_RS08540	COG4372	Transposase
COG34_RS08545	COG3436	PFAM IS66 Orf2 family protein
COG34_RS08620	COG3344	reverse transcriptase
COG34_RS08710	COG3596	GTP binding
COG34_RS08740	COG2003	Belongs to the UPF0758 family
COG34_RS08785	COG3609	addiction module antidote protein, CC2985 family
COG34_RS08800	COG3710	Transcriptional regulator
COG34_RS08810	COG0531	amino acid
COG34_RS08815	COG1982	Orn Lys Arg decarboxylase major
COG34_RS08820	COG3104	oligopeptide transport
COG34_RS08825	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
COG34_RS08850	COG3592	Divergent 4Fe-4S mono-cluster
COG34_RS08855	COG3290	protein histidine kinase activity
COG34_RS08860	COG4565	transcriptional regulatory protein
COG34_RS08870	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
COG34_RS08875	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
COG34_RS08875	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
COG34_RS08880	COG3647	Membrane
COG34_RS08890	COG2211	Major facilitator Superfamily
COG34_RS08895	COG1486	melibiose metabolic process
COG34_RS08905	COG2169	Transcriptional regulator
COG34_RS08910	COG1982	Orn Lys Arg decarboxylase major
COG34_RS08915	COG2207	Transcriptional regulator
COG34_RS08920	COG0531	amino acid
COG34_RS08925	COG2194	sulfuric ester hydrolase activity
COG34_RS08930	COG0745	RESPONSE REGULATOR receiver
COG34_RS08935	COG0642	Histidine kinase
COG34_RS08945	COG0477	Major facilitator Superfamily
COG34_RS08965	COG2824	Alkylphosphonate utilization operon protein PhnA
COG34_RS08970	COG2764	glyoxalase bleomycin resistance protein dioxygenase
COG34_RS08980	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
COG34_RS08990	COG3639	organic phosphonate transmembrane transporter activity
COG34_RS08995	COG2188	Transcriptional regulator
COG34_RS09000	COG3624	Phosphonate C-P lyase system protein PhnG
COG34_RS09005	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
COG34_RS09010	COG3626	phosphonate metabolism
COG34_RS09015	COG3627	carbon phosphorus lyase activity
COG34_RS09020	COG4107	phosphonate C-P lyase system protein PhnK
COG34_RS09025	COG4778	phosphonate C-P lyase system protein PhnL
COG34_RS09030	COG3454	Phosphonate metabolism
COG34_RS09035	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
COG34_RS09040	COG0456	acetyltransferase
COG34_RS09045	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
COG34_RS09055	COG0698	ribose 5-phosphate isomerase
COG34_RS09060	COG2015	COG2015, Alkyl sulfatase and related hydrolases
COG34_RS09070	COG1566	PFAM secretion protein HlyD family protein
COG34_RS09075	COG1289	transmembrane transporter activity
COG34_RS09090	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
COG34_RS09095	COG1301	dicarboxylic acid transport
COG34_RS09105	COG4235	cytochrome complex assembly
COG34_RS09110	COG3088	subunit of a heme lyase
COG34_RS09115	COG1138	Cytochrome C-type biogenesis protein
COG34_RS09120	COG3301	Polysulphide reductase, NrfD
COG34_RS09125	COG0437	4 iron, 4 sulfur cluster binding
COG34_RS09130	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
COG34_RS09145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
COG34_RS09150	COG3162	membrane
COG34_RS09160	COG1357	PFAM Pentapeptide repeats (8 copies)
COG34_RS09165	COG0025	NhaP-type Na H and K H
COG34_RS09170	COG2252	PERMEase
COG34_RS09190	COG0789	Transcriptional regulator
COG34_RS09195	COG2207	Transcriptional regulator
COG34_RS09200	COG4943	cyclic-guanylate-specific phosphodiesterase activity
COG34_RS09215	COG0629	single-stranded DNA binding
COG34_RS09220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
COG34_RS09225	COG2315	Protein conserved in bacteria
COG34_RS09230	COG0432	Pfam Uncharacterised protein family UPF0047
COG34_RS09235	COG3700	Belongs to the class B bacterial acid phosphatase family
COG34_RS09245	COG1448	Aminotransferase
COG34_RS09250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COG34_RS09255	COG0305	Participates in initiation and elongation during chromosome replication
COG34_RS09260	COG0604	alcohol dehydrogenase
COG34_RS09270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COG34_RS09285	COG0735	belongs to the Fur family
COG34_RS09290	COG3237	CsbD-like
COG34_RS09295	COG0534	Mate efflux family protein
COG34_RS09305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
COG34_RS09330	COG1357	PFAM Pentapeptide repeats (8 copies)
COG34_RS09350	COG3842	ATPase activity
COG34_RS09360	COG2182	Extracellular solute-binding protein
COG34_RS09365	COG1175	transmembrane transport
COG34_RS09370	COG3833	ABC-type maltose transport systems, permease component
COG34_RS09375	COG2814	Major facilitator Superfamily
COG34_RS09375	COG0477	Major facilitator Superfamily
COG34_RS09390	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COG34_RS09420	COG0527	aspartate kinase activity
COG34_RS09425	COG0542	response to heat
COG34_RS09430	COG3541	Predicted nucleotidyltransferase
COG34_RS09445	COG1187	pseudouridine synthase activity
COG34_RS09455	COG1283	sodium-dependent phosphate transmembrane transporter activity
COG34_RS09460	COG1410	methionine synthase
COG34_RS09460	COG0646	methionine synthase
COG34_RS09465	COG1414	Transcriptional regulator
COG34_RS09485	COG2224	Isocitrate lyase
COG34_RS09490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
COG34_RS09500	COG0456	acetyltransferase
COG34_RS09535	COG0151	Belongs to the GarS family
COG34_RS09540	COG2204	response regulator
COG34_RS09545	COG4191	Histidine kinase
COG34_RS09555	COG3678	ATP-independent chaperone mediated protein folding
COG34_RS09570	COG3068	Protein conserved in bacteria
COG34_RS09605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
COG34_RS09610	COG2104	thiamine diphosphate biosynthetic process
COG34_RS09620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
COG34_RS09665	COG0250	Participates in transcription elongation, termination and antitermination
COG34_RS09670	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
COG34_RS09715	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
COG34_RS09715	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
COG34_RS09780	COG0583	DNA-binding transcription factor activity
COG34_RS09785	COG2271	Major facilitator Superfamily
COG34_RS09790	COG4948	Mandelate Racemase Muconate Lactonizing
COG34_RS09810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
COG34_RS09825	COG2194	sulfuric ester hydrolase activity
COG34_RS09830	COG2207	Transcriptional regulator
COG34_RS09835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS09840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COG34_RS09845	COG1882	Formate acetyltransferase
COG34_RS09850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS09855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS09860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS09860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COG34_RS09860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS09865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COG34_RS09870	COG0371	Dehydrogenase
COG34_RS09875	COG3738	Protein conserved in bacteria
COG34_RS09880	COG0697	spore germination
COG34_RS09890	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
COG34_RS09895	COG0460	homoserine dehydrogenase
COG34_RS09895	COG0527	aspartate kinase activity
COG34_RS09900	COG0626	cystathionine gamma-synthase activity
COG34_RS09910	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
COG34_RS09925	COG3209	COG3209 Rhs family protein
COG34_RS09935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COG34_RS09940	COG1609	Transcriptional regulator
COG34_RS09945	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
COG34_RS09960	COG1575	Belongs to the MenA family. Type 1 subfamily
COG34_RS09975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
COG34_RS09985	COG1494	fructose-1,6-bisphosphatase
COG34_RS09995	COG0589	response to stress
COG34_RS10000	COG3691	Protein conserved in bacteria
COG34_RS10005	COG3152	Membrane
COG34_RS10025	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
COG34_RS10040	COG3678	ATP-independent chaperone mediated protein folding
COG34_RS10045	COG0745	RESPONSE REGULATOR receiver
COG34_RS10050	COG2205	protein histidine kinase activity
COG34_RS10055	COG2258	MOSC domain
COG34_RS10070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
COG34_RS10110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS10115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS10115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS10120	COG1363	Peptidase, m42
COG34_RS10125	COG3711	transcriptional antiterminator
COG34_RS10125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS10145	COG0243	molybdopterin cofactor binding
COG34_RS10145	COG3383	formate dehydrogenase (NAD+) activity
COG34_RS10150	COG0243	molybdopterin cofactor binding
COG34_RS10150	COG3383	formate dehydrogenase (NAD+) activity
COG34_RS10155	COG0437	4 iron, 4 sulfur cluster binding
COG34_RS10160	COG2864	formate dehydrogenase
COG34_RS10170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
COG34_RS10175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
COG34_RS10190	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
COG34_RS10200	COG0456	acetyltransferase
COG34_RS10215	COG1011	Hydrolase
COG34_RS10220	COG1349	DNA-binding transcription factor activity
COG34_RS10225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COG34_RS10230	COG2084	Dehydrogenase
COG34_RS10235	COG3684	Belongs to the aldolase LacD family
COG34_RS10240	COG2942	2-epimerase
COG34_RS10245	COG2017	converts alpha-aldose to the beta-anomer
COG34_RS10250	COG1501	Belongs to the glycosyl hydrolase 31 family
COG34_RS10255	COG2211	Major facilitator Superfamily
COG34_RS10260	COG2211	Major facilitator Superfamily
COG34_RS10265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
COG34_RS10270	COG2271	Major facilitator Superfamily
COG34_RS10275	COG1082	Xylose isomerase domain protein TIM barrel
COG34_RS10280	COG2188	Transcriptional regulator
COG34_RS10285	COG1217	gtp-binding protein TYPA
COG34_RS10295	COG0174	glutamine synthetase
COG34_RS10305	COG3852	Histidine kinase
COG34_RS10310	COG2204	response regulator
COG34_RS10320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
COG34_RS10340	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COG34_RS10340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COG34_RS10350	COG0204	Acyl-transferase
COG34_RS10355	COG5339	Protein conserved in bacteria
COG34_RS10360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
COG34_RS10365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
COG34_RS10370	COG3084	Protein conserved in bacteria
COG34_RS10375	COG0746	molybdenum cofactor guanylyltransferase activity
COG34_RS10380	COG1763	Mo-molybdopterin cofactor biosynthetic process
COG34_RS10410	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
COG34_RS10415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
COG34_RS10420	COG1739	Uncharacterized protein family UPF0029
COG34_RS10440	COG0543	2 iron, 2 sulfur cluster binding
COG34_RS10445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
COG34_RS10450	COG0250	Participates in transcription elongation, termination and antitermination
COG34_RS10460	COG0805	protein transport
COG34_RS10465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
COG34_RS10470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
COG34_RS10480	COG3165	ubiquinone biosynthetic process from chorismate
COG34_RS10490	COG1322	Protein conserved in bacteria
COG34_RS10495	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
COG34_RS10500	COG0412	Dienelactone hydrolase
COG34_RS10510	COG0583	DNA-binding transcription factor activity
COG34_RS10515	COG0697	spore germination
COG34_RS10520	COG0561	phosphatase activity
COG34_RS10525	COG2267	carboxylic ester hydrolase activity
COG34_RS10530	COG1280	lysine exporter protein (LysE YggA)
COG34_RS10535	COG1280	lysine exporter protein (LysE YggA)
COG34_RS10540	COG0514	ATP-dependent DNA helicase (RecQ)
COG34_RS10545	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
COG34_RS10550	COG2050	protein possibly involved in aromatic compounds catabolism
COG34_RS10555	COG2962	Rard protein
COG34_RS10585	COG0598	Magnesium transport protein CorA
COG34_RS10590	COG3698	Phosphodiester glycosidase
COG34_RS10595	COG0210	DNA helicase
COG34_RS10600	COG1011	Hydrolase
COG34_RS10610	COG3159	Protein conserved in bacteria
COG34_RS10620	COG5567	small periplasmic lipoprotein
COG34_RS10645	COG3072	Adenylate cyclase
COG34_RS10660	COG1587	Uroporphyrinogen-III synthase
COG34_RS10665	COG2959	enzyme of heme biosynthesis
COG34_RS10670	COG3071	HemY protein
COG34_RS10675	COG0641	radical SAM
COG34_RS10700	COG1113	amino acid transport
COG34_RS10720	COG2244	polysaccharide biosynthetic process
COG34_RS10725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
COG34_RS10730	COG0456	acetyltransferase
COG34_RS10735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COG34_RS10740	COG1088	dTDP-glucose 4,6-dehydratase activity
COG34_RS10745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
COG34_RS10750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
COG34_RS10755	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
COG34_RS10760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COG34_RS10770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
COG34_RS10780	COG3118	belongs to the thioredoxin family
COG34_RS10800	COG0210	DNA helicase
COG34_RS10805	COG3692	DNA binding
COG34_RS10810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
COG34_RS10820	COG0583	DNA-binding transcription factor activity
COG34_RS10825	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS10835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
COG34_RS10845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
COG34_RS10850	COG3978	acetolactate synthase activity
COG34_RS10870	COG0606	chelatase, subunit chli
COG34_RS10875	COG3085	chromosome segregation
COG34_RS10915	COG2186	Transcriptional regulator
COG34_RS10920	COG0477	Major facilitator Superfamily
COG34_RS10925	COG1609	Transcriptional regulator
COG34_RS10930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COG34_RS10935	COG1879	ABC-type sugar transport system periplasmic component
COG34_RS10940	COG1172	Belongs to the binding-protein-dependent transport system permease family
COG34_RS10945	COG1129	ABC transporter
COG34_RS10975	COG1522	sequence-specific DNA binding
COG34_RS10980	COG0716	FMN binding
COG34_RS10995	COG3312	ion transport
COG34_RS11050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
COG34_RS11065	COG3188	usher protein
COG34_RS11075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
COG34_RS11080	COG0573	inorganic phosphate transmembrane transporter activity
COG34_RS11085	COG0581	inorganic phosphate transmembrane transporter activity
COG34_RS11090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
COG34_RS11095	COG0704	Plays a role in the regulation of phosphate uptake
COG34_RS11100	COG3711	transcriptional antiterminator
COG34_RS11105	COG2190	(PTS) system
COG34_RS11105	COG1263	PTS System
COG34_RS11105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS11110	COG2723	6-phospho-beta-galactosidase activity
COG34_RS11120	COG2382	esterase
COG34_RS11125	COG0363	glucosamine-6-phosphate deaminase activity
COG34_RS11130	COG3196	Protein conserved in bacteria
COG34_RS11140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
COG34_RS11145	COG2252	PERMEase
COG34_RS11150	COG0431	NADPH-dependent FMN reductase
COG34_RS11155	COG2091	lysine biosynthetic process via aminoadipic acid
COG34_RS11170	COG0814	amino acid
COG34_RS11220	COG0592	DNA-directed DNA polymerase activity
COG34_RS11230	COG0187	DNA topoisomerase II activity
COG34_RS11235	COG3753	Protein conserved in bacteria
COG34_RS11240	COG0561	phosphatase activity
COG34_RS11250	COG2186	Transcriptional regulator
COG34_RS11255	COG3734	2-keto-3-deoxy-galactonokinase
COG34_RS11260	COG0800	Aldolase
COG34_RS11270	COG2271	Major facilitator Superfamily
COG34_RS11280	COG0823	Involved in the tonB-independent uptake of proteins
COG34_RS11285	COG5645	(Lipo)protein
COG34_RS11305	COG2188	Transcriptional regulator
COG34_RS11325	COG2207	Transcriptional regulator
COG34_RS11330	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COG34_RS11335	COG3119	arylsulfatase activity
COG34_RS11345	COG2149	membrane
COG34_RS11355	COG0641	radical SAM
COG34_RS11360	COG2814	Major facilitator Superfamily
COG34_RS11395	COG0028	Belongs to the TPP enzyme family
COG34_RS11400	COG0440	acetolactate synthase activity
COG34_RS11405	COG2197	response regulator
COG34_RS11410	COG3851	Histidine kinase
COG34_RS11415	COG2271	Major facilitator Superfamily
COG34_RS11420	COG2271	Major facilitator Superfamily
COG34_RS11430	COG2252	PERMEase
COG34_RS11460	COG1464	Belongs to the NlpA lipoprotein family
COG34_RS11465	COG0697	spore germination
COG34_RS11470	COG2814	Major facilitator Superfamily
COG34_RS11490	COG2211	Major facilitator Superfamily
COG34_RS11495	COG1501	Belongs to the glycosyl hydrolase 31 family
COG34_RS11500	COG2982	Protein involved in outer membrane biogenesis
COG34_RS11505	COG2233	PERMEase
COG34_RS11510	COG0786	glutamate:sodium symporter activity
COG34_RS11520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COG34_RS11525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COG34_RS11530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COG34_RS11540	COG0194	GDP metabolic process
COG34_RS11550	COG2860	membrane
COG34_RS11555	COG3645	SOS response
COG34_RS11560	COG1561	YicC-like family, N-terminal region
COG34_RS11590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COG34_RS11620	COG1519	Transferase
COG34_RS11625	COG0859	PFAM glycosyl transferase family 9
COG34_RS11630	COG0438	transferase activity, transferring glycosyl groups
COG34_RS11635	COG0515	serine threonine protein kinase
COG34_RS11650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
COG34_RS11655	COG1442	glycosyl transferase family 8
COG34_RS11660	COG1216	Glycosyl transferase, family 2
COG34_RS11665	COG3307	-O-antigen
COG34_RS11670	COG0859	PFAM glycosyl transferase family 9
COG34_RS11675	COG0859	PFAM glycosyl transferase family 9
COG34_RS11685	COG0156	8-amino-7-oxononanoate synthase activity
COG34_RS11695	COG1216	Glycosyl transferase, family 2
COG34_RS11700	COG2861	carbohydrate metabolic process
COG34_RS11705	COG4942	peptidase
COG34_RS11720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COG34_RS11725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
COG34_RS11740	COG1045	serine acetyltransferase
COG34_RS11745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
COG34_RS11755	COG2186	Transcriptional regulator
COG34_RS11760	COG1620	l-lactate permease
COG34_RS11770	COG5295	Hep Hag repeat protein
COG34_RS11795	COG3722	fumarate hydratase activity
COG34_RS11805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS11805	COG2213	PTS system mannitol-specific
COG34_RS11815	COG1566	PFAM secretion protein HlyD family protein
COG34_RS11835	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
COG34_RS11845	COG1413	lyase activity
COG34_RS11855	COG3209	COG3209 Rhs family protein
COG34_RS11860	COG0625	glutathione transferase activity
COG34_RS11870	COG3276	selenocysteine insertion sequence binding
COG34_RS11875	COG1454	alcohol dehydrogenase
COG34_RS11880	COG1012	belongs to the aldehyde dehydrogenase family
COG34_RS11900	COG1566	PFAM secretion protein HlyD family protein
COG34_RS11905	COG0583	DNA-binding transcription factor activity
COG34_RS11910	COG3713	MltA-interacting MipA family protein
COG34_RS11920	COG2211	Major facilitator Superfamily
COG34_RS11930	COG0235	Class ii aldolase
COG34_RS11935	COG3623	hexulose-6-phosphate isomerase
COG34_RS11940	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
COG34_RS11945	COG1070	Carbohydrate kinase
COG34_RS11950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
COG34_RS11955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
COG34_RS11960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
COG34_RS11965	COG2731	YhcH YjgK YiaL family protein
COG34_RS11975	COG1414	Transcriptional regulator
COG34_RS11980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS11985	COG3977	Valine--pyruvate aminotransferase
COG34_RS11990	COG0366	Alpha amylase catalytic
COG34_RS11995	COG2992	FlgJ-related protein
COG34_RS12000	COG1609	Transcriptional regulator
COG34_RS12000	COG2207	Transcriptional regulator
COG34_RS12005	COG4214	carbohydrate transport
COG34_RS12010	COG1129	ABC transporter
COG34_RS12015	COG4213	ABC transporter substrate-binding protein
COG34_RS12025	COG1070	Carbohydrate kinase
COG34_RS12030	COG4682	membrane
COG34_RS12035	COG4682	membrane
COG34_RS12040	COG3274	enterobacterial common antigen metabolic process
COG34_RS12065	COG1278	Cold shock
COG34_RS12070	COG2944	sequence-specific DNA binding
COG34_RS12085	COG2885	chlorophyll binding
COG34_RS12090	COG0243	molybdopterin cofactor binding
COG34_RS12095	COG0456	acetyltransferase
COG34_RS12100	COG2818	Glycosylase
COG34_RS12105	COG5571	outer membrane autotransporter
COG34_RS12115	COG2223	nitrite transmembrane transporter activity
COG34_RS12120	COG2194	sulfuric ester hydrolase activity
COG34_RS12140	COG0747	negative chemotaxis
COG34_RS12145	COG0601	transmembrane transport
COG34_RS12150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
COG34_RS12155	COG0444	Belongs to the ABC transporter superfamily
COG34_RS12160	COG4608	Belongs to the ABC transporter superfamily
COG34_RS12165	COG0814	amino acid
COG34_RS12205	COG2194	sulfuric ester hydrolase activity
COG34_RS12230	COG1215	transferase activity, transferring glycosyl groups
COG34_RS12235	COG1215	transferase activity, transferring glycosyl groups
COG34_RS12240	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
COG34_RS12245	COG3118	belongs to the thioredoxin family
COG34_RS12245	COG0457	Tetratricopeptide repeat
COG34_RS12250	COG2200	EAL domain
COG34_RS12250	COG2199	diguanylate cyclase activity
COG34_RS12265	COG0612	Peptidase, M16
COG34_RS12280	COG2200	EAL domain
COG34_RS12285	COG2982	Protein involved in outer membrane biogenesis
COG34_RS12290	COG0477	Major facilitator Superfamily
COG34_RS12295	COG1295	ribonuclease BN
COG34_RS12300	COG0583	DNA-binding transcription factor activity
COG34_RS12305	COG2197	response regulator
COG34_RS12315	COG1858	cytochrome C peroxidase
COG34_RS12320	COG0076	glutamate decarboxylase activity
COG34_RS12330	COG2207	Transcriptional regulator
COG34_RS12340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COG34_RS12345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COG34_RS12355	COG2771	luxR family
COG34_RS12360	COG3247	response to pH
COG34_RS12375	COG1285	pathogenesis
COG34_RS12380	COG2197	response regulator
COG34_RS12390	COG3065	identical protein binding
COG34_RS12410	COG1393	Belongs to the ArsC family
COG34_RS12415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
COG34_RS12420	COG0640	Transcriptional regulator
COG34_RS12435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COG34_RS12440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
COG34_RS12445	COG0339	signal peptide processing
COG34_RS12455	COG3104	oligopeptide transport
COG34_RS12465	COG0589	response to stress
COG34_RS12475	COG0306	phosphate transporter
COG34_RS12480	COG2081	HI0933 family
COG34_RS12545	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COG34_RS12580	COG4372	Transposase
COG34_RS12585	COG3436	PFAM IS66 Orf2 family protein
COG34_RS12595	COG0739	heme binding
COG34_RS12605	COG2132	Multicopper oxidase
COG34_RS12610	COG3667	copper resistance
COG34_RS12615	COG2372	response to copper ion
COG34_RS12620	COG1276	copper resistance
COG34_RS12625	COG0745	RESPONSE REGULATOR receiver
COG34_RS12630	COG2205	protein histidine kinase activity
COG34_RS12660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COG34_RS12665	COG0842	Transport permease protein
COG34_RS12665	COG1129	ABC transporter
COG34_RS12670	COG0842	Transport permease protein
COG34_RS12695	COG0444	Belongs to the ABC transporter superfamily
COG34_RS12700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
COG34_RS12705	COG0601	transmembrane transport
COG34_RS12710	COG0747	negative chemotaxis
COG34_RS12715	COG2091	lysine biosynthetic process via aminoadipic acid
COG34_RS12720	COG0628	permease
COG34_RS12735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
COG34_RS12750	COG3714	YhhN family
COG34_RS12760	COG3776	membrane
COG34_RS12765	COG0742	ribosomal rna small subunit methyltransferase
COG34_RS12770	COG0552	protein localization to endoplasmic reticulum
COG34_RS12775	COG2884	Cell division ATP-binding protein ftsE
COG34_RS12780	COG2177	Part of the ABC transporter FtsEX involved in
COG34_RS12785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COG34_RS12790	COG0683	leucine binding
COG34_RS12805	COG0456	acetyltransferase
COG34_RS12815	COG0683	leucine binding
COG34_RS12820	COG0559	Belongs to the binding-protein-dependent transport system permease family
COG34_RS12825	COG4177	L-phenylalanine transmembrane transporter activity
COG34_RS12830	COG0411	ABC transporter
COG34_RS12835	COG0410	ABC transporter
COG34_RS12840	COG1653	transport
COG34_RS12845	COG1175	transmembrane transport
COG34_RS12855	COG3842	ATPase activity
COG34_RS12860	COG0584	glycerophosphoryl diester phosphodiesterase
COG34_RS12870	COG0405	Gamma-glutamyltransferase
COG34_RS12890	COG3157	Type VI secretion system effector, Hcp
COG34_RS12895	COG1247	-acetyltransferase
COG34_RS12905	COG0673	inositol 2-dehydrogenase activity
COG34_RS12910	COG1741	Belongs to the pirin family
COG34_RS12915	COG1609	Transcriptional regulator
COG34_RS12920	COG3265	gluconokinase activity
COG34_RS12925	COG2610	gluconate transmembrane transporter activity
COG34_RS12930	COG2095	MarC family integral membrane protein
COG34_RS12935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COG34_RS12960	COG0058	SHG alpha-glucan phosphorylase activity
COG34_RS12970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
COG34_RS12990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
COG34_RS13005	COG1349	DNA-binding transcription factor activity
COG34_RS13010	COG4650	regulator
COG34_RS13015	COG1690	Belongs to the RtcB family
COG34_RS13030	COG1690	Belongs to the RtcB family
COG34_RS13045	COG0058	SHG alpha-glucan phosphorylase activity
COG34_RS13050	COG1640	4-alpha-glucanotransferase
COG34_RS13055	COG2610	gluconate transmembrane transporter activity
COG34_RS13075	COG5464	transposase or invertase
COG34_RS13090	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
COG34_RS13095	COG1918	ferrous iron import across plasma membrane
COG34_RS13105	COG2183	response to ionizing radiation
COG34_RS13110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
COG34_RS13150	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
COG34_RS13160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
COG34_RS13165	COG1011	Hydrolase
COG34_RS13175	COG0494	nUDIX hydrolase
COG34_RS13180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
COG34_RS13185	COG4972	Pilus assembly protein
COG34_RS13190	COG3166	PFAM Fimbrial assembly family protein
COG34_RS13205	COG4796	Type ii and iii secretion system protein
COG34_RS13225	COG3266	domain, Protein
COG34_RS13230	COG0338	D12 class N6 adenine-specific DNA methyltransferase
COG34_RS13235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
COG34_RS13240	COG0546	phosphoglycolate phosphatase activity
COG34_RS13245	COG0180	Tryptophanyl-tRNA synthetase
COG34_RS13250	COG2188	Transcriptional regulator
COG34_RS13260	COG3457	Alanine racemase
COG34_RS13265	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
COG34_RS13270	COG1735	metal-dependent hydrolase with the TIM-barrel fold
COG34_RS13285	COG0626	cystathionine gamma-synthase activity
COG34_RS13290	COG2188	Transcriptional regulator
COG34_RS13300	COG1082	Xylose isomerase domain protein TIM barrel
COG34_RS13310	COG2222	sugar isomerase
COG34_RS13315	COG0531	amino acid
COG34_RS13330	COG2116	formate transmembrane transporter activity
COG34_RS13335	COG2146	nitrite reductase [NAD(P)H] activity
COG34_RS13340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
COG34_RS13350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COG34_RS13360	COG2184	nucleotidyltransferase activity
COG34_RS13365	COG0512	Glutamine amidotransferase of anthranilate synthase
COG34_RS13370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
COG34_RS13375	COG1289	transmembrane transporter activity
COG34_RS13380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
COG34_RS13390	COG1765	OsmC-like protein
COG34_RS13395	COG3954	Phosphoribulokinase
COG34_RS13405	COG0429	hydrolase of the alpha beta-hydrolase fold
COG34_RS13410	COG0488	(ABC) transporter
COG34_RS13430	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
COG34_RS13435	COG1047	Peptidyl-prolyl cis-trans
COG34_RS13445	COG0545	Peptidyl-prolyl cis-trans isomerase
COG34_RS13450	COG2964	Protein conserved in bacteria
COG34_RS13530	COG0089	rRNA binding
COG34_RS13620	COG0201	protein transport
COG34_RS13660	COG0789	Transcriptional regulator
COG34_RS13665	COG3036	rescue of stalled ribosome
COG34_RS13675	COG0569	domain protein
COG34_RS13695	COG0758	DNA mediated transformation
COG34_RS13705	COG0551	DNA topoisomerase type I activity
COG34_RS13725	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
COG34_RS13765	COG1126	abc transporter atp-binding protein
COG34_RS13770	COG0765	amino acid transport
COG34_RS13775	COG4597	amino acid ABC transporter
COG34_RS13780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
COG34_RS13795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COG34_RS13800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COG34_RS13810	COG1309	transcriptional regulator
COG34_RS13820	COG2189	Belongs to the N(4) N(6)-methyltransferase family
COG34_RS13830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COG34_RS13840	COG4145	pantothenate transmembrane transporter activity
COG34_RS13845	COG3924	membrane
COG34_RS13850	COG0439	Biotin carboxylase
COG34_RS13855	COG0511	ligase activity, forming carbon-carbon bonds
COG34_RS13865	COG0604	alcohol dehydrogenase
COG34_RS13870	COG2199	diguanylate cyclase activity
COG34_RS13870	COG2200	EAL domain
COG34_RS13885	COG1077	Cell shape determining protein MreB Mrl
COG34_RS13890	COG1792	Involved in formation and maintenance of cell shape
COG34_RS13895	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
COG34_RS13905	COG1530	ribonuclease E activity
COG34_RS13910	COG3164	Protein of unknown function
COG34_RS13915	COG0312	modulator of DNA gyrase
COG34_RS13920	COG0583	DNA-binding transcription factor activity
COG34_RS13940	COG2732	(Barnase) inhibitor
COG34_RS13960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COG34_RS13965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COG34_RS13970	COG3105	Protein conserved in bacteria
COG34_RS13975	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
COG34_RS14005	COG0625	glutathione transferase activity
COG34_RS14010	COG2969	positive regulation of protein catabolic process
COG34_RS14015	COG3069	C4-dicarboxylate transmembrane transporter activity
COG34_RS14050	COG2731	YhcH YjgK YiaL family protein
COG34_RS14055	COG4804	nuclease activity
COG34_RS14060	COG0493	'glutamate synthase
COG34_RS14065	COG0067	glutamate synthase
COG34_RS14065	COG0069	glutamate synthase activity
COG34_RS14065	COG0070	glutamate synthase
COG34_RS14080	COG1242	4 iron, 4 sulfur cluster binding
COG34_RS14085	COG0784	Response regulator, receiver
COG34_RS14085	COG2198	Histidine kinase
COG34_RS14085	COG5002	protein histidine kinase activity
COG34_RS14090	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
COG34_RS14100	COG0515	serine threonine protein kinase
COG34_RS14105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS14120	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COG34_RS14125	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
COG34_RS14130	COG1137	ATPase activity
COG34_RS14135	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
COG34_RS14140	COG3117	lipopolysaccharide transmembrane transporter activity
COG34_RS14145	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
COG34_RS14150	COG0517	IMP dehydrogenase activity
COG34_RS14150	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
COG34_RS14155	COG0530	calcium, potassium:sodium antiporter activity
COG34_RS14160	COG1127	ABC transporter
COG34_RS14165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
COG34_RS14170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
COG34_RS14175	COG2854	intermembrane phospholipid transfer
COG34_RS14180	COG3113	response to antibiotic
COG34_RS14185	COG5007	Belongs to the BolA IbaG family
COG34_RS14195	COG3423	Transcriptional regulator
COG34_RS14200	COG0142	geranyltranstransferase activity
COG34_RS14215	COG0697	spore germination
COG34_RS14225	COG2027	D-alanyl-D-alanine carboxypeptidase
COG34_RS14230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
COG34_RS14235	COG1534	Rna-binding protein
COG34_RS14245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COG34_RS14250	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
COG34_RS14260	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
COG34_RS14270	COG2194	sulfuric ester hydrolase activity
COG34_RS14290	COG0195	Participates in both transcription termination and antitermination
COG34_RS14330	COG0513	Belongs to the DEAD box helicase family
COG34_RS14335	COG0814	amino acid
COG34_RS14345	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS14350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COG34_RS14355	COG0826	peptidase U32
COG34_RS14360	COG0826	peptidase U32
COG34_RS14365	COG3154	lipid carrier protein
COG34_RS14370	COG3153	acetyltransferase
COG34_RS14385	COG0693	protein deglycase activity
COG34_RS14390	COG0702	epimerase
COG34_RS14395	COG0701	Predicted permease
COG34_RS14400	COG2823	Periplasmic or secreted lipoprotein
COG34_RS14420	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COG34_RS14425	COG3539	Fimbrial protein
COG34_RS14430	COG3188	usher protein
COG34_RS14435	COG3121	Chaperone
COG34_RS14440	COG3539	Fimbrial protein
COG34_RS14445	COG0363	glucosamine-6-phosphate deaminase activity
COG34_RS14450	COG3716	PTS system mannose fructose sorbose family IID component
COG34_RS14455	COG3715	PTS system
COG34_RS14460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS14470	COG2222	sugar isomerase
COG34_RS14475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
COG34_RS14480	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS14485	COG3716	PTS system mannose fructose sorbose family IID component
COG34_RS14495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS14510	COG1349	DNA-binding transcription factor activity
COG34_RS14520	COG2002	toxin-antitoxin pair type II binding
COG34_RS14525	COG2721	sulfolactate sulfo-lyase activity
COG34_RS14530	COG2271	Major facilitator Superfamily
COG34_RS14540	COG2084	Dehydrogenase
COG34_RS14545	COG1929	Belongs to the glycerate kinase type-1 family
COG34_RS14570	COG0583	DNA-binding transcription factor activity
COG34_RS14580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
COG34_RS14590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COG34_RS14595	COG1882	Formate acetyltransferase
COG34_RS14600	COG0251	oxidation-reduction process
COG34_RS14605	COG1760	l-serine dehydratase
COG34_RS14615	COG0814	amino acid
COG34_RS14630	COG1741	Belongs to the pirin family
COG34_RS14635	COG0583	DNA-binding transcription factor activity
COG34_RS14645	COG3152	Membrane
COG34_RS14650	COG3152	Membrane
COG34_RS14655	COG0435	Glutathione S-transferase
COG34_RS14660	COG2259	Doxx family
COG34_RS14670	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
COG34_RS14675	COG4575	ribosome binding
COG34_RS14680	COG1422	Protein of unknown function (DUF1090)
COG34_RS14690	COG0586	Pfam SNARE associated Golgi protein
COG34_RS14695	COG2186	Transcriptional regulator
COG34_RS14725	COG2271	Major facilitator Superfamily
COG34_RS14735	COG2721	sulfolactate sulfo-lyase activity
COG34_RS14745	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
COG34_RS14755	COG0861	Integral membrane protein TerC family
COG34_RS14760	COG0673	inositol 2-dehydrogenase activity
COG34_RS14765	COG2949	membrane
COG34_RS14770	COG1451	nucleotide metabolic process
COG34_RS14780	COG4680	protein conserved in bacteria
COG34_RS14785	COG5499	transcription regulator containing HTH domain
COG34_RS14790	COG0446	pyridine nucleotide-disulphide oxidoreductase
COG34_RS14790	COG1902	pentaerythritol trinitrate reductase activity
COG34_RS14795	COG3408	Glycogen debranching enzyme
COG34_RS14795	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
COG34_RS14805	COG0531	amino acid
COG34_RS14810	COG2731	YhcH YjgK YiaL family protein
COG34_RS14815	COG3250	beta-galactosidase activity
COG34_RS14820	COG1609	Transcriptional regulator
COG34_RS14830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COG34_RS14845	COG0840	transmembrane signaling receptor activity
COG34_RS14850	COG1695	Transcriptional regulator
COG34_RS14855	COG2375	cellular response to nickel ion
COG34_RS14870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COG34_RS14880	COG0358	DNA primase activity
COG34_RS14885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
COG34_RS14895	COG0471	metal ion transport
COG34_RS14900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
COG34_RS14905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
COG34_RS14915	COG0583	DNA-binding transcription factor activity
COG34_RS14925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COG34_RS14940	COG4991	sh3 domain protein
COG34_RS14950	COG3025	triphosphatase activity
COG34_RS14970	COG2268	Band 7 protein
COG34_RS14975	COG1585	Membrane protein implicated in regulation of membrane protease activity
COG34_RS14985	COG3539	Fimbrial protein
COG34_RS14990	COG3121	Chaperone
COG34_RS14995	COG3188	usher protein
COG34_RS15000	COG3539	Fimbrial protein
COG34_RS15005	COG2960	long-chain fatty acid transporting porin activity
COG34_RS15025	COG3384	dioxygenase
COG34_RS15030	COG0754	glutathionylspermidine amidase activity
COG34_RS15045	COG1538	Outer membrane efflux protein
COG34_RS15050	COG0494	nUDIX hydrolase
COG34_RS15055	COG3151	Protein conserved in bacteria
COG34_RS15060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
COG34_RS15065	COG3150	esterase
COG34_RS15070	COG0187	DNA topoisomerase II activity
COG34_RS15090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COG34_RS15115	COG2211	Major facilitator Superfamily
COG34_RS15120	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
COG34_RS15125	COG2249	NAD(P)H dehydrogenase (quinone) activity
COG34_RS15135	COG0642	Histidine kinase
COG34_RS15140	COG0745	RESPONSE REGULATOR receiver
COG34_RS15145	COG3111	PFAM Bacterial OB fold (BOF) protein
COG34_RS15150	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
COG34_RS15160	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COG34_RS15165	COG0204	Acyl-transferase
COG34_RS15170	COG2132	Multicopper oxidase
COG34_RS15175	COG1032	radical SAM domain protein
COG34_RS15180	COG4238	major outer membrane lipoprotein
COG34_RS15190	COG0656	L-ascorbic acid biosynthetic process
COG34_RS15195	COG1979	alcohol dehydrogenase
COG34_RS15200	COG2207	Transcriptional regulator
COG34_RS15205	COG0586	Pfam SNARE associated Golgi protein
COG34_RS15210	COG0626	cystathionine gamma-synthase activity
COG34_RS15220	COG0811	peptide transport
COG34_RS15225	COG0848	biopolymer transport protein
COG34_RS15235	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS15240	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS15250	COG0667	Aldo Keto reductase
COG34_RS15270	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
COG34_RS15275	COG0437	4 iron, 4 sulfur cluster binding
COG34_RS15280	COG5557	Pfam Polysulphide reductase, NrfD
COG34_RS15285	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
COG34_RS15290	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
COG34_RS15295	COG1773	rubredoxin
COG34_RS15300	COG0375	protein maturation
COG34_RS15305	COG0298	carbon dioxide binding
COG34_RS15310	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS15320	COG0625	glutathione transferase activity
COG34_RS15325	COG0754	glutathionylspermidine amidase activity
COG34_RS15330	COG0306	phosphate transporter
COG34_RS15335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COG34_RS15340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COG34_RS15345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COG34_RS15350	COG2244	polysaccharide biosynthetic process
COG34_RS15360	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
COG34_RS15365	COG0795	lipopolysaccharide-transporting ATPase activity
COG34_RS15375	COG0156	8-amino-7-oxononanoate synthase activity
COG34_RS15380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COG34_RS15390	COG0318	PFAM AMP-dependent synthetase and ligase
COG34_RS15400	COG0456	acetyltransferase
COG34_RS15405	COG2186	Transcriptional regulator
COG34_RS15410	COG0277	FAD linked oxidase domain protein
COG34_RS15415	COG0277	FAD linked oxidase domain protein
COG34_RS15420	COG0247	lactate metabolic process
COG34_RS15425	COG3193	protein, possibly involved in utilization of glycolate and propanediol
COG34_RS15430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
COG34_RS15435	COG1620	l-lactate permease
COG34_RS15445	COG3064	Membrane
COG34_RS15470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
COG34_RS15480	COG2165	general secretion pathway protein
COG34_RS15510	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
COG34_RS15520	COG1811	Na channel or pump
COG34_RS15530	COG1982	Orn Lys Arg decarboxylase major
COG34_RS15535	COG2211	Major facilitator Superfamily
COG34_RS15550	COG1194	a g-specific adenine glycosylase
COG34_RS15565	COG3171	Protein conserved in bacteria
COG34_RS15575	COG0252	asparaginase activity
COG34_RS15585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
COG34_RS15600	COG0762	integral membrane protein
COG34_RS15605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COG34_RS15610	COG2805	Type II/IV secretion system protein
COG34_RS15620	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS15635	COG0189	ligase activity
COG34_RS15640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
COG34_RS15645	COG2356	endonuclease I
COG34_RS15655	COG2814	Major facilitator Superfamily
COG34_RS15680	COG1166	arginine decarboxylase activity
COG34_RS15695	COG0501	Belongs to the peptidase M48B family
COG34_RS15700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COG34_RS15705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS15710	COG2213	PTS system mannitol-specific
COG34_RS15715	COG1063	alcohol dehydrogenase
COG34_RS15720	COG1494	fructose-1,6-bisphosphatase
COG34_RS15730	COG1072	(Pantothenic acid kinase))
COG34_RS15735	COG1122	ATPase activity
COG34_RS15740	COG1122	ATPase activity
COG34_RS15775	COG0191	fructose-bisphosphate aldolase activity
COG34_RS15785	COG0668	transmembrane transport
COG34_RS15795	COG2968	Membrane
COG34_RS15800	COG0583	DNA-binding transcription factor activity
COG34_RS15805	COG0427	acetyl-CoA hydrolase
COG34_RS15815	COG1703	isobutyryl-CoA mutase activity
COG34_RS15820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
COG34_RS15820	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
COG34_RS15840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
COG34_RS15855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COG34_RS15880	COG0006	proline dipeptidase activity
COG34_RS15885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
COG34_RS15890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
COG34_RS15910	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS15915	COG2723	6-phospho-beta-galactosidase activity
COG34_RS15925	COG1272	protein, Hemolysin III
COG34_RS15935	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
COG34_RS15945	COG0716	FMN binding
COG34_RS15950	COG4974	Belongs to the 'phage' integrase family
COG34_RS15955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
COG34_RS15960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
COG34_RS15985	COG2233	PERMEase
COG34_RS15995	COG0493	'glutamate synthase
COG34_RS15995	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS16000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS16005	COG2252	PERMEase
COG34_RS16010	COG0402	S-adenosylhomocysteine deaminase activity
COG34_RS16015	COG2233	PERMEase
COG34_RS16020	COG2080	2 iron, 2 sulfur cluster binding
COG34_RS16020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
COG34_RS16025	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
COG34_RS16030	COG0402	S-adenosylhomocysteine deaminase activity
COG34_RS16035	COG0493	'glutamate synthase
COG34_RS16035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS16040	COG2068	MobA-Related Protein
COG34_RS16045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COG34_RS16050	COG3608	succinylglutamate desuccinylase aspartoacylase
COG34_RS16050	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
COG34_RS16055	COG0549	Belongs to the carbamate kinase family
COG34_RS16065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
COG34_RS16070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
COG34_RS16075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COG34_RS16080	COG3829	transcription factor binding
COG34_RS16085	COG2080	2 iron, 2 sulfur cluster binding
COG34_RS16090	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
COG34_RS16095	COG1529	Aldehyde oxidase and xanthine dehydrogenase
COG34_RS16105	COG4942	peptidase
COG34_RS16115	COG3387	PFAM Glycoside hydrolase 15-related
COG34_RS16205	COG2197	response regulator
COG34_RS16210	COG2197	response regulator
COG34_RS16225	COG0457	Tetratricopeptide repeat
COG34_RS16225	COG3710	Transcriptional regulator
COG34_RS16230	COG0457	Tetratricopeptide repeat
COG34_RS16260	COG3710	Transcriptional regulator
COG34_RS16265	COG2771	luxR family
COG34_RS16270	COG0814	amino acid
COG34_RS16275	COG0183	Belongs to the thiolase family
COG34_RS16285	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS16290	COG2814	Major facilitator Superfamily
COG34_RS16295	COG1794	racemase activity, acting on amino acids and derivatives
COG34_RS16300	COG0583	DNA-binding transcription factor activity
COG34_RS16310	COG1609	Transcriptional regulator
COG34_RS16325	COG0667	Aldo Keto reductase
COG34_RS16335	COG0861	Integral membrane protein TerC family
COG34_RS16350	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
COG34_RS16365	COG2165	general secretion pathway protein
COG34_RS16370	COG4795	General secretion pathway protein
COG34_RS16380	COG4967	type IV pilus modification protein PilV
COG34_RS16385	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
COG34_RS16390	COG1025	Belongs to the peptidase M16 family
COG34_RS16395	COG1074	ATP-dependent DNA helicase activity
COG34_RS16400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
COG34_RS16405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
COG34_RS16405	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
COG34_RS16410	COG0860	N-Acetylmuramoyl-L-alanine amidase
COG34_RS16435	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
COG34_RS16440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
COG34_RS16445	COG2166	iron-sulfur cluster assembly
COG34_RS16450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COG34_RS16460	COG0583	DNA-binding transcription factor activity
COG34_RS16465	COG2363	Small membrane protein
COG34_RS16475	COG1349	DNA-binding transcription factor activity
COG34_RS16485	COG1070	Carbohydrate kinase
COG34_RS16495	COG0738	Major facilitator superfamily
COG34_RS16500	COG0235	Class ii aldolase
COG34_RS16505	COG1454	alcohol dehydrogenase
COG34_RS16515	COG1760	l-serine dehydratase
COG34_RS16520	COG0814	amino acid
COG34_RS16525	COG1611	Belongs to the LOG family
COG34_RS16540	COG3098	single-species biofilm formation
COG34_RS16545	COG0564	pseudouridine synthase activity
COG34_RS16550	COG0716	FMN binding
COG34_RS16555	COG2271	Major facilitator Superfamily
COG34_RS16560	COG4948	Mandelate Racemase Muconate Lactonizing
COG34_RS16565	COG4948	Mandelate Racemase Muconate Lactonizing
COG34_RS16595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COG34_RS16600	COG2336	PFAM SpoVT AbrB
COG34_RS16605	COG2337	Toxic component of a toxin-antitoxin (TA) module
COG34_RS16610	COG3956	TIGRFAM MazG family protein
COG34_RS16630	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
COG34_RS16640	COG0602	queuosine metabolic process
COG34_RS16650	COG0720	synthase
COG34_RS16680	COG1203	CRISPR-associated helicase, Cas3
COG34_RS16695	COG1857	crispr-associated protein
COG34_RS16710	COG1518	maintenance of DNA repeat elements
COG34_RS16715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
COG34_RS16720	COG2234	aminopeptidase activity
COG34_RS16775	COG4942	peptidase
COG34_RS16775	COG1388	LysM domain
COG34_RS16780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COG34_RS16795	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
COG34_RS16805	COG2610	gluconate transmembrane transporter activity
COG34_RS16810	COG3622	Belongs to the hyi family
COG34_RS16815	COG0235	Class ii aldolase
COG34_RS16820	COG3395	kinase activity
COG34_RS16825	COG2084	Dehydrogenase
COG34_RS16830	COG1349	DNA-binding transcription factor activity
COG34_RS16835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
COG34_RS16855	COG3604	Transcriptional regulator
COG34_RS16860	COG0309	Hydrogenase expression formation protein (HypE)
COG34_RS16865	COG0409	Hydrogenase expression formation protein
COG34_RS16870	COG0298	carbon dioxide binding
COG34_RS16875	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
COG34_RS16880	COG0375	protein maturation
COG34_RS16890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS16895	COG0651	ATP synthesis coupled electron transport
COG34_RS16900	COG0650	Formate hydrogenlyase subunit 4
COG34_RS16905	COG3261	NADH dehydrogenase
COG34_RS16905	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
COG34_RS16910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
COG34_RS16915	COG3260	NADH ubiquinone oxidoreductase 20
COG34_RS16925	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
COG34_RS16930	COG2723	6-phospho-beta-galactosidase activity
COG34_RS16935	COG1263	PTS System
COG34_RS16935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS16940	COG1609	Transcriptional regulator
COG34_RS16945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS16950	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
COG34_RS16975	COG1349	DNA-binding transcription factor activity
COG34_RS16980	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS16985	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS16995	COG3732	PTS system glucitol sorbitol-specific
COG34_RS17000	COG3730	PTS system glucitol sorbitol-specific
COG34_RS17005	COG2951	lytic endotransglycosylase activity
COG34_RS17010	COG1546	Belongs to the CinA family
COG34_RS17030	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
COG34_RS17060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
COG34_RS17065	COG1238	metal cluster binding
COG34_RS17080	COG2814	Major facilitator Superfamily
COG34_RS17085	COG1566	PFAM secretion protein HlyD family protein
COG34_RS17090	COG1846	Transcriptional regulator
COG34_RS17100	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
COG34_RS17105	COG2814	Major facilitator Superfamily
COG34_RS17110	COG2113	Glycine betaine
COG34_RS17115	COG4176	ABC-type proline glycine betaine transport system permease component
COG34_RS17120	COG4175	Glycine betaine
COG34_RS17125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COG34_RS17130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COG34_RS17140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
COG34_RS17145	COG4575	ribosome binding
COG34_RS17160	COG2916	Histone family protein nucleoid-structuring protein H-NS
COG34_RS17165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COG34_RS17170	COG0640	Transcriptional regulator
COG34_RS17175	COG0401	homolog of Blt101
COG34_RS17180	COG1652	LysM domain
COG34_RS17185	COG1802	Transcriptional regulator
COG34_RS17190	COG1113	amino acid transport
COG34_RS17195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COG34_RS17200	COG1012	belongs to the aldehyde dehydrogenase family
COG34_RS17205	COG0579	oxidoreductase
COG34_RS17250	COG3468	outer membrane autotransporter barrel domain protein
COG34_RS17260	COG3596	GTP binding
COG34_RS17265	COG3311	Transcriptional regulator
COG34_RS17305	COG0582	viral genome integration into host DNA
COG34_RS17320	COG2867	negative regulation of translational initiation
COG34_RS17330	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COG34_RS17335	COG0497	DNA recombination
COG34_RS17355	COG4536	flavin adenine dinucleotide binding
COG34_RS17360	COG4137	Cytochrome C assembly protein
COG34_RS17365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COG34_RS17390	COG2885	chlorophyll binding
COG34_RS17395	COG2199	diguanylate cyclase activity
COG34_RS17410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
COG34_RS17415	COG0287	Prephenate dehydrogenase
COG34_RS17415	COG1605	Chorismate mutase
COG34_RS17420	COG0077	Prephenate dehydratase
COG34_RS17420	COG1605	Chorismate mutase
COG34_RS17425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COG34_RS17435	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COG34_RS17440	COG0564	pseudouridine synthase activity
COG34_RS17445	COG1496	oxidoreductase activity
COG34_RS17450	COG0542	response to heat
COG34_RS17480	COG0477	Major facilitator Superfamily
COG34_RS17485	COG5544	Lipoprotein
COG34_RS17490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COG34_RS17495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COG34_RS17495	COG1042	CoA-binding domain protein
COG34_RS17495	COG0045	succinate-CoA ligase (ADP-forming) activity
COG34_RS17500	COG3148	PFAM DTW domain containing protein
COG34_RS17505	COG3118	belongs to the thioredoxin family
COG34_RS17515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COG34_RS17535	COG0583	DNA-binding transcription factor activity
COG34_RS17540	COG0513	Belongs to the DEAD box helicase family
COG34_RS17550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
COG34_RS17555	COG1595	DNA-templated transcription, initiation
COG34_RS17560	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
COG34_RS17565	COG3026	antisigma factor binding
COG34_RS17570	COG3086	response to oxidative stress
COG34_RS17580	COG0681	Belongs to the peptidase S26 family
COG34_RS17605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
COG34_RS17630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS17635	COG1737	Transcriptional regulator
COG34_RS17640	COG0560	Phosphoserine phosphatase
COG34_RS17660	COG2205	protein histidine kinase activity
COG34_RS17665	COG3170	Tfp pilus assembly protein FimV
COG34_RS17670	COG2204	response regulator
COG34_RS17675	COG0347	Belongs to the P(II) protein family
COG34_RS17680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
COG34_RS17680	COG1017	nitric oxide dioxygenase activity
COG34_RS17690	COG1940	carbohydrate kinase activity
COG34_RS17695	COG0457	Tetratricopeptide repeat
COG34_RS17700	COG1879	ABC-type sugar transport system periplasmic component
COG34_RS17705	COG1129	ABC transporter
COG34_RS17710	COG1172	Belongs to the binding-protein-dependent transport system permease family
COG34_RS17715	COG1063	alcohol dehydrogenase
COG34_RS17720	COG2017	converts alpha-aldose to the beta-anomer
COG34_RS17725	COG2259	Doxx family
COG34_RS17750	COG4638	Rieske (2fe-2S)
COG34_RS17755	COG0583	DNA-binding transcription factor activity
COG34_RS17760	COG2814	Major facilitator Superfamily
COG34_RS17765	COG3711	transcriptional antiterminator
COG34_RS17770	COG1073	alpha beta
COG34_RS17775	COG0483	inositol monophosphate 1-phosphatase activity
COG34_RS17795	COG0822	iron-sulfur transferase activity
COG34_RS17815	COG0633	Ferredoxin
COG34_RS17820	COG2975	iron-sulfur cluster assembly
COG34_RS17835	COG2897	thiosulfate sulfurtransferase activity
COG34_RS17840	COG2373	Large extracellular alpha-helical protein
COG34_RS17845	COG4953	penicillin-binding protein 1C
COG34_RS17880	COG2976	Protein conserved in bacteria
COG34_RS17895	COG1645	bacterial-type flagellum-dependent swarming motility
COG34_RS17905	COG0516	GMP reductase activity
COG34_RS17905	COG0517	IMP dehydrogenase activity
COG34_RS17920	COG3133	Outer membrane lipoprotein
COG34_RS17940	COG2200	EAL domain
COG34_RS17945	COG0248	Ppx GppA phosphatase
COG34_RS17950	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COG34_RS17955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COG34_RS17975	COG2233	PERMEase
COG34_RS17985	COG1393	Belongs to the ArsC family
COG34_RS17990	COG4783	chaperone-mediated protein folding
COG34_RS17995	COG0628	permease
COG34_RS18025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
COG34_RS18030	COG3261	NADH dehydrogenase
COG34_RS18030	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
COG34_RS18035	COG0651	ATP synthesis coupled electron transport
COG34_RS18040	COG4237	Hydrogenase 4 membrane
COG34_RS18050	COG0650	Formate hydrogenlyase subunit 4
COG34_RS18055	COG0651	ATP synthesis coupled electron transport
COG34_RS18060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS18065	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
COG34_RS18070	COG2716	regulation of RNA biosynthetic process
COG34_RS18080	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
COG34_RS18100	COG2321	neutral zinc metallopeptidase
COG34_RS18110	COG0400	carboxylic ester hydrolase activity
COG34_RS18125	COG1393	Belongs to the ArsC family
COG34_RS18140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COG34_RS18145	COG3850	Histidine kinase
COG34_RS18150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS18150	COG0493	'glutamate synthase
COG34_RS18160	COG5342	invasion associated locus B
COG34_RS18165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COG34_RS18170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COG34_RS18175	COG0280	phosphate acetyltransferase
COG34_RS18175	COG0281	malic enzyme
COG34_RS18185	COG4810	utilization protein
COG34_RS18190	COG4917	ethanolamine utilization protein
COG34_RS18195	COG4766	ethanolamine catabolic process
COG34_RS18200	COG4812	Cobalamin adenosyltransferase
COG34_RS18205	COG0280	phosphate acetyltransferase
COG34_RS18210	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
COG34_RS18215	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
COG34_RS18220	COG1012	belongs to the aldehyde dehydrogenase family
COG34_RS18225	COG4820	ethanolamine utilization protein (EutJ)
COG34_RS18230	COG1454	alcohol dehydrogenase
COG34_RS18235	COG3192	ethanolamine utilization protein
COG34_RS18240	COG4819	ethanolamine utilization protein
COG34_RS18245	COG4303	Ethanolamine ammonia lyase large subunit
COG34_RS18255	COG4816	utilization protein
COG34_RS18260	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
COG34_RS18265	COG2207	Transcriptional regulator
COG34_RS18275	COG0860	N-Acetylmuramoyl-L-alanine amidase
COG34_RS18295	COG2837	iron assimilation
COG34_RS18300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
COG34_RS18305	COG1263	PTS System
COG34_RS18305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS18320	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS18325	COG4150	thiosulfate binding
COG34_RS18330	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
COG34_RS18335	COG4208	sulfate ABC transporter
COG34_RS18340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
COG34_RS18345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
COG34_RS18360	COG2190	(PTS) system
COG34_RS18365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COG34_RS18370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS18375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
COG34_RS18395	COG3530	Putative quorum-sensing-regulated virulence factor
COG34_RS18400	COG0385	Bile acid
COG34_RS18405	COG0583	DNA-binding transcription factor activity
COG34_RS18415	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
COG34_RS18420	COG2211	Major facilitator Superfamily
COG34_RS18430	COG0583	DNA-binding transcription factor activity
COG34_RS18470	COG3415	Transposase
COG34_RS18475	COG3415	Transposase
COG34_RS18490	COG2200	EAL domain
COG34_RS18490	COG2199	diguanylate cyclase activity
COG34_RS18495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COG34_RS18520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS18525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS18530	COG0006	proline dipeptidase activity
COG34_RS18535	COG1363	Peptidase, m42
COG34_RS18545	COG2207	Transcriptional regulator
COG34_RS18550	COG3279	Response regulator of the LytR AlgR family
COG34_RS18555	COG3275	phosphorelay sensor kinase activity
COG34_RS18560	COG0436	Aminotransferase
COG34_RS18570	COG1560	Kdo2-lipid A biosynthetic process
COG34_RS18600	COG0028	Belongs to the TPP enzyme family
COG34_RS18605	COG0679	Auxin Efflux Carrier
COG34_RS18610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
COG34_RS18615	COG0784	Response regulator, receiver
COG34_RS18615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
COG34_RS18615	COG2198	Histidine kinase
COG34_RS18615	COG2205	protein histidine kinase activity
COG34_RS18620	COG2197	response regulator
COG34_RS18625	COG1566	PFAM secretion protein HlyD family protein
COG34_RS18630	COG0477	Major facilitator Superfamily
COG34_RS18970	COG2246	polysaccharide biosynthetic process
COG34_RS18975	COG0582	viral genome integration into host DNA
COG34_RS18985	COG2116	formate transmembrane transporter activity
COG34_RS18995	COG2853	Lipoprotein
COG34_RS19010	COG2067	long-chain fatty acid transport protein
COG34_RS19020	COG3691	Protein conserved in bacteria
COG34_RS19035	COG2062	phosphohistidine phosphatase, SixA
COG34_RS19040	COG3539	Fimbrial protein
COG34_RS19045	COG3188	usher protein
COG34_RS19050	COG3121	Chaperone
COG34_RS19055	COG3539	Fimbrial protein
COG34_RS19060	COG3539	Fimbrial protein
COG34_RS19065	COG3539	Fimbrial protein
COG34_RS19095	COG0730	response to heat
COG34_RS19100	COG3101	peptidyl-lysine hydroxylation
COG34_RS19115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
COG34_RS19125	COG2814	Major facilitator Superfamily
COG34_RS19140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COG34_RS19150	COG0586	Pfam SNARE associated Golgi protein
COG34_RS19160	COG0285	dihydrofolate synthase activity
COG34_RS19165	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
COG34_RS19170	COG1286	toxin biosynthetic process
COG34_RS19175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COG34_RS19180	COG0163	prenyltransferase activity
COG34_RS19185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
COG34_RS19190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
COG34_RS19195	COG4215	(ABC) transporter
COG34_RS19200	COG4160	amino acid transport
COG34_RS19205	COG4598	ABC transporter
COG34_RS19210	COG5464	transposase or invertase
COG34_RS19215	COG1090	epimerase
COG34_RS19220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COG34_RS19225	COG0625	glutathione transferase activity
COG34_RS19230	COG0625	glutathione transferase activity
COG34_RS19235	COG0622	Phosphoesterase
COG34_RS19240	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
COG34_RS19245	COG1288	antiporter activity
COG34_RS19250	COG0280	phosphate acetyltransferase
COG34_RS19250	COG0857	belongs to the CobB CobQ family
COG34_RS19255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COG34_RS19270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
COG34_RS19275	COG0490	domain, Protein
COG34_RS19275	COG0471	metal ion transport
COG34_RS19285	COG0436	Aminotransferase
COG34_RS19295	COG0583	DNA-binding transcription factor activity
COG34_RS19315	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
COG34_RS19320	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
COG34_RS19325	COG1034	ATP synthesis coupled electron transport
COG34_RS19340	COG0839	Belongs to the complex I subunit 6 family
COG34_RS19350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
COG34_RS19355	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
COG34_RS19370	COG2234	aminopeptidase activity
COG34_RS19390	COG2153	protein acetylation
COG34_RS19395	COG4575	ribosome binding
COG34_RS19400	COG1169	isochorismate synthase
COG34_RS19415	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
COG34_RS19425	COG0318	PFAM AMP-dependent synthetase and ligase
COG34_RS19495	COG5464	transposase or invertase
COG34_RS19500	COG0247	lactate metabolic process
COG34_RS19510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
COG34_RS19515	COG2271	Major facilitator Superfamily
COG34_RS19520	COG0584	glycerophosphoryl diester phosphodiesterase
COG34_RS19525	COG0583	DNA-binding transcription factor activity
COG34_RS19530	COG3642	lipopolysaccharide core region biosynthetic process
COG34_RS19535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
COG34_RS19540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COG34_RS19545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COG34_RS19555	COG3468	outer membrane autotransporter barrel domain protein
COG34_RS19565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COG34_RS19570	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
COG34_RS19575	COG3234	Protein of unknown function (DUF1175)
COG34_RS19585	COG5445	Predicted secreted protein (DUF2300)
COG34_RS19590	COG4676	Protein conserved in bacteria
COG34_RS19595	COG0784	Response regulator, receiver
COG34_RS19595	COG2205	protein histidine kinase activity
COG34_RS19600	COG2197	response regulator
COG34_RS19605	COG0642	Histidine kinase
COG34_RS19605	COG2198	Histidine kinase
COG34_RS19625	COG1477	protein flavinylation
COG34_RS19630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COG34_RS19630	COG2169	Transcriptional regulator
COG34_RS19635	COG3145	DNA-N1-methyladenine dioxygenase activity
COG34_RS19640	COG4615	Cyclic peptide transporter
COG34_RS19660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS19660	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
COG34_RS19665	COG3062	negative regulation of establishment of protein localization
COG34_RS19675	COG0437	4 iron, 4 sulfur cluster binding
COG34_RS19680	COG0348	domain, Protein
COG34_RS19685	COG3043	anaerobic respiration
COG34_RS19690	COG3005	denitrification pathway
COG34_RS19695	COG4133	protoheme IX ABC transporter activity
COG34_RS19700	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
COG34_RS19705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
COG34_RS19710	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
COG34_RS19720	COG1138	Cytochrome C-type biogenesis protein
COG34_RS19725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
COG34_RS19730	COG3088	subunit of a heme lyase
COG34_RS19730	COG4235	cytochrome complex assembly
COG34_RS19735	COG2197	response regulator
COG34_RS19745	COG3468	outer membrane autotransporter barrel domain protein
COG34_RS19750	COG3468	outer membrane autotransporter barrel domain protein
COG34_RS19760	COG3083	sulfuric ester hydrolase activity
COG34_RS19780	COG1061	Type III restriction enzyme res subunit
COG34_RS19790	COG1187	pseudouridine synthase activity
COG34_RS19795	COG2814	Major facilitator Superfamily
COG34_RS19810	COG4172	Belongs to the ABC transporter superfamily
COG34_RS19815	COG4239	(ABC) transporter, permease
COG34_RS19820	COG4174	ABC transporter (Permease)
COG34_RS19825	COG4166	transmembrane transport
COG34_RS19830	COG2200	EAL domain
COG34_RS19835	COG0791	NLP P60 protein
COG34_RS19840	COG0671	phosphoesterase, PA-phosphatase related
COG34_RS19845	COG0523	cobalamin synthesis protein
COG34_RS19850	COG0246	Mannitol dehydrogenase
COG34_RS19865	COG2814	Major facilitator Superfamily
COG34_RS19870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS19870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS19875	COG1105	Belongs to the carbohydrate kinase PfkB family
COG34_RS19880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS19880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COG34_RS19880	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
COG34_RS19885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COG34_RS19890	COG2313	pseudouridylate synthase activity
COG34_RS19895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COG34_RS19900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
COG34_RS19910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COG34_RS19915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COG34_RS19915	COG1522	sequence-specific DNA binding
COG34_RS19925	COG2855	membrane
COG34_RS19930	COG0583	DNA-binding transcription factor activity
COG34_RS19940	COG0833	amino acid
COG34_RS19950	COG4771	TonB-dependent receptor
COG34_RS19975	COG2311	Membrane
COG34_RS19985	COG1609	Transcriptional regulator
COG34_RS19990	COG1879	ABC-type sugar transport system periplasmic component
COG34_RS19995	COG1129	ABC transporter
COG34_RS20000	COG4211	Belongs to the binding-protein-dependent transport system permease family
COG34_RS20005	COG0167	dihydroorotate dehydrogenase activity
COG34_RS20005	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
COG34_RS20010	COG0493	'glutamate synthase
COG34_RS20020	COG2949	membrane
COG34_RS20030	COG1346	cytolysis
COG34_RS20040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COG34_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS20070	COG0586	Pfam SNARE associated Golgi protein
COG34_RS20080	COG1686	Belongs to the peptidase S11 family
COG34_RS20085	COG0277	FAD linked oxidase domain protein
COG34_RS20090	COG1472	Belongs to the glycosyl hydrolase 3 family
COG34_RS20095	COG1732	Glycine betaine
COG34_RS20100	COG1174	glycine betaine transport
COG34_RS20105	COG1125	glycine betaine transport
COG34_RS20110	COG1174	glycine betaine transport
COG34_RS20120	COG0789	Transcriptional regulator
COG34_RS20125	COG3275	phosphorelay sensor kinase activity
COG34_RS20130	COG3279	Response regulator of the LytR AlgR family
COG34_RS20135	COG4807	Protein conserved in bacteria
COG34_RS20140	COG4808	Protein conserved in bacteria
COG34_RS20145	COG4715	Zinc finger, swim domain protein
COG34_RS20150	COG3552	Protein containing von Willebrand factor type A (VWA) domain
COG34_RS20155	COG2425	protein containing a von Willebrand factor type A (vWA) domain
COG34_RS20160	COG0714	Associated with various cellular activities
COG34_RS20170	COG3831	ATPase activity
COG34_RS20175	COG3831	ATPase activity
COG34_RS20185	COG0489	protein tyrosine kinase activity
COG34_RS20200	COG3539	Fimbrial protein
COG34_RS20205	COG3121	Chaperone
COG34_RS20210	COG3188	usher protein
COG34_RS20215	COG3539	Fimbrial protein
COG34_RS20220	COG5455	response to cobalt ion
COG34_RS20240	COG0351	phosphomethylpyrimidine kinase
COG34_RS20245	COG3757	hydrolase, family 25
COG34_RS20250	COG2188	Transcriptional regulator
COG34_RS20255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COG34_RS20260	COG1397	ADP-ribosylglycohydrolase
COG34_RS20265	COG2211	Major facilitator Superfamily
COG34_RS20270	COG1830	Aldolase
COG34_RS20285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS20290	COG3414	Phosphotransferase system galactitol-specific IIB component
COG34_RS20295	COG3775	system Galactitol-specific IIC component
COG34_RS20325	COG4974	Belongs to the 'phage' integrase family
COG34_RS20395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COG34_RS20400	COG4695	Portal protein
COG34_RS20510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
COG34_RS20555	COG0826	peptidase U32
COG34_RS20565	COG0745	RESPONSE REGULATOR receiver
COG34_RS20570	COG2205	protein histidine kinase activity
COG34_RS20600	COG4245	von Willebrand factor, type A
COG34_RS20605	COG0631	protein serine/threonine phosphatase activity
COG34_RS20610	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
COG34_RS20615	COG0443	Heat shock 70 kDa protein
COG34_RS20620	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
COG34_RS20625	COG3447	MASE1 domain protein
COG34_RS20625	COG5001	Diguanylate cyclase
COG34_RS20625	COG5002	protein histidine kinase activity
COG34_RS20630	COG0572	uridine kinase
COG34_RS20640	COG2982	Protein involved in outer membrane biogenesis
COG34_RS20645	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS20655	COG1253	flavin adenine dinucleotide binding
COG34_RS20660	COG1596	polysaccharide export
COG34_RS20665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COG34_RS20670	COG0489	protein tyrosine kinase activity
COG34_RS20670	COG3206	protein involved in exopolysaccharide biosynthesis
COG34_RS20675	COG0463	Glycosyl transferase, family 2
COG34_RS20680	COG1045	serine acetyltransferase
COG34_RS20685	COG0438	transferase activity, transferring glycosyl groups
COG34_RS20695	COG1216	Glycosyl transferase, family 2
COG34_RS20700	COG0110	maltose O-acetyltransferase activity
COG34_RS20705	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
COG34_RS20710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
COG34_RS20715	COG1051	belongs to the nudix hydrolase family
COG34_RS20720	COG0297	glycogen (starch) synthase activity
COG34_RS20725	COG0662	Cupin 2, conserved barrel domain protein
COG34_RS20725	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
COG34_RS20730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COG34_RS20735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
COG34_RS20740	COG2244	polysaccharide biosynthetic process
COG34_RS20745	COG2327	Polysaccharide pyruvyl transferase
COG34_RS20750	COG0438	transferase activity, transferring glycosyl groups
COG34_RS20760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
COG34_RS20765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
COG34_RS20770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
COG34_RS20780	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
COG34_RS20785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
COG34_RS20790	COG1051	belongs to the nudix hydrolase family
COG34_RS20795	COG0662	Cupin 2, conserved barrel domain protein
COG34_RS20795	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
COG34_RS20800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COG34_RS20840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
COG34_RS20845	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COG34_RS20850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COG34_RS20875	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
COG34_RS20880	COG0131	Imidazoleglycerol-phosphate dehydratase
COG34_RS20880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
COG34_RS20890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
COG34_RS20910	COG2161	toxin-antitoxin pair type II binding
COG34_RS20915	COG4115	mRNA cleavage
COG34_RS20920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
COG34_RS20925	COG0583	DNA-binding transcription factor activity
COG34_RS20935	COG0531	amino acid
COG34_RS20940	COG2391	methyltransferase activity
COG34_RS20945	COG0425	Belongs to the sulfur carrier protein TusA family
COG34_RS20950	COG2925	Exonuclease
COG34_RS20955	COG1686	Belongs to the peptidase S11 family
COG34_RS20985	COG4917	ethanolamine utilization protein
COG34_RS21010	COG3436	PFAM IS66 Orf2 family protein
COG34_RS21015	COG4372	Transposase
COG34_RS21020	COG3436	PFAM IS66 Orf2 family protein
COG34_RS21025	COG4372	Transposase
COG34_RS21035	COG2200	EAL domain
COG34_RS21035	COG2771	luxR family
COG34_RS21060	COG0582	viral genome integration into host DNA
COG34_RS21095	COG2003	Belongs to the UPF0758 family
COG34_RS21125	COG3468	outer membrane autotransporter barrel domain protein
COG34_RS21230	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
COG34_RS21245	COG1376	ErfK ybiS ycfS ynhG family protein
COG34_RS21285	COG2916	Histone family protein nucleoid-structuring protein H-NS
COG34_RS21380	COG0582	viral genome integration into host DNA
COG34_RS21390	COG0583	DNA-binding transcription factor activity
COG34_RS21395	COG0583	DNA-binding transcription factor activity
COG34_RS21405	COG0534	Mate efflux family protein
COG34_RS21425	COG0217	transcriptional regulatory protein
COG34_RS21430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COG34_RS21435	COG0477	Major facilitator Superfamily
COG34_RS21445	COG1388	LysM domain
COG34_RS21445	COG1470	cell adhesion involved in biofilm formation
COG34_RS21450	COG1470	cell adhesion involved in biofilm formation
COG34_RS21450	COG1388	LysM domain
COG34_RS21455	COG1388	LysM domain
COG34_RS21455	COG1470	cell adhesion involved in biofilm formation
COG34_RS21460	COG1388	LysM domain
COG34_RS21460	COG2373	Large extracellular alpha-helical protein
COG34_RS21460	COG4932	domain protein
COG34_RS21465	COG4771	TonB-dependent receptor
COG34_RS21470	COG1021	2,3-dihydroxybenzoate-AMP ligase
COG34_RS21505	COG1132	(ABC) transporter
COG34_RS21510	COG2814	Major facilitator Superfamily
COG34_RS21515	COG1169	isochorismate synthase
COG34_RS21520	COG0582	viral genome integration into host DNA
COG34_RS21670	COG0582	viral genome integration into host DNA
COG34_RS21695	COG3443	Belongs to the bacterial solute-binding protein 9 family
COG34_RS21710	COG2351	hydroxyisourate hydrolase activity
COG34_RS21715	COG0745	RESPONSE REGULATOR receiver
COG34_RS21720	COG2205	protein histidine kinase activity
COG34_RS21735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
COG34_RS21745	COG1418	mRNA catabolic process
COG34_RS21750	COG0270	DNA (cytosine-5-)-methyltransferase activity
COG34_RS21755	COG3727	T/G mismatch-specific endonuclease activity
COG34_RS21760	COG0697	spore germination
COG34_RS21765	COG2354	Protein conserved in bacteria
COG34_RS21770	COG5475	Uncharacterized small protein (DUF2158)
COG34_RS21800	COG2197	response regulator
COG34_RS21805	COG1684	flagellar biosynthetic protein fliR
COG34_RS21810	COG1987	bacterial-type flagellum assembly
COG34_RS21815	COG1338	Plays a role in the flagellum-specific transport system
COG34_RS21820	COG3190	flagellar
COG34_RS21825	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
COG34_RS21830	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
COG34_RS21835	COG1580	Controls the rotational direction of flagella during chemotaxis
COG34_RS21840	COG3144	bacterial-type flagellum assembly
COG34_RS21845	COG2882	bacterial-type flagellum organization
COG34_RS21850	COG1157	protein secretion by the type III secretion system
COG34_RS21855	COG1317	bacterial-type flagellum organization
COG34_RS21860	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
COG34_RS21865	COG1766	The M ring may be actively involved in energy transduction
COG34_RS21880	COG2135	peptidase activity
COG34_RS21885	COG0425	Belongs to the sulfur carrier protein TusA family
COG34_RS21890	COG2391	methyltransferase activity
COG34_RS21905	COG0366	Alpha amylase catalytic
COG34_RS21915	COG1516	flagellar protein fliS
COG34_RS21930	COG1191	sigma factor activity
COG34_RS21940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
COG34_RS21950	COG0765	amino acid transport
COG34_RS21955	COG1126	abc transporter atp-binding protein
COG34_RS21960	COG2197	response regulator
COG34_RS21970	COG2197	response regulator
COG34_RS22000	COG3318	Belongs to the UPF0149 family
COG34_RS22000	COG3012	SEC-C Motif Domain Protein
COG34_RS22005	COG0814	amino acid
COG34_RS22015	COG1528	Iron-storage protein
COG34_RS22040	COG1528	Iron-storage protein
COG34_RS22050	COG1879	ABC-type sugar transport system periplasmic component
COG34_RS22055	COG1129	ABC transporter
COG34_RS22060	COG1172	Belongs to the binding-protein-dependent transport system permease family
COG34_RS22065	COG1877	trehalose-phosphatase activity
COG34_RS22075	COG0589	response to stress
COG34_RS22090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
COG34_RS22095	COG1360	Flagellar Motor Protein
COG34_RS22100	COG0643	Histidine kinase
COG34_RS22100	COG2198	Histidine kinase
COG34_RS22105	COG0835	chemotaxis
COG34_RS22110	COG0840	transmembrane signaling receptor activity
COG34_RS22115	COG0840	transmembrane signaling receptor activity
COG34_RS22120	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
COG34_RS22130	COG0745	RESPONSE REGULATOR receiver
COG34_RS22135	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
COG34_RS22140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
COG34_RS22145	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
COG34_RS22155	COG3755	Protein conserved in bacteria
COG34_RS22170	COG3102	Protein conserved in bacteria
COG34_RS22180	COG3005	denitrification pathway
COG34_RS22185	COG0243	molybdopterin cofactor binding
COG34_RS22195	COG3547	Transposase (IS116 IS110 IS902 family)
COG34_RS22210	COG3788	relative of glutathione S-transferase, MAPEG superfamily
COG34_RS22215	COG1801	Protein of unknown function DUF72
COG34_RS22220	COG1335	isochorismatase
COG34_RS22230	COG0494	nUDIX hydrolase
COG34_RS22235	COG0217	transcriptional regulatory protein
COG34_RS22265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
COG34_RS22275	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
COG34_RS22280	COG0739	heme binding
COG34_RS22285	COG1560	Kdo2-lipid A biosynthetic process
COG34_RS22290	COG0469	pyruvate kinase activity
COG34_RS22295	COG1737	Transcriptional regulator
COG34_RS22300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COG34_RS22305	COG0129	dihydroxy-acid dehydratase activity
COG34_RS22310	COG0800	Aldolase
COG34_RS22320	COG3141	response to X-ray
COG34_RS22330	COG2979	Protein of unknown function (DUF533)
COG34_RS22335	COG1770	oligopeptidase
COG34_RS22340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
COG34_RS22345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
COG34_RS22355	COG2372	response to copper ion
COG34_RS22360	COG1276	copper resistance
COG34_RS22370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
COG34_RS22390	COG3008	intermembrane lipid transfer
COG34_RS22395	COG2995	paraquat-inducible protein a
COG34_RS22400	COG1956	GAF domain-containing protein
COG34_RS22410	COG0793	Belongs to the peptidase S41A family
COG34_RS22420	COG2814	Major facilitator Superfamily
COG34_RS22425	COG1414	Transcriptional regulator
COG34_RS22460	COG2226	methyltransferase
COG34_RS22480	COG3716	PTS system mannose fructose sorbose family IID component
COG34_RS22485	COG3715	PTS system
COG34_RS22490	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS22490	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
COG34_RS22505	COG1253	flavin adenine dinucleotide binding
COG34_RS22510	COG2200	EAL domain
COG34_RS22515	COG1760	l-serine dehydratase
COG34_RS22525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COG34_RS22540	COG0251	oxidation-reduction process
COG34_RS22545	COG1199	ATP-dependent helicase activity
COG34_RS22550	COG1214	PFAM Peptidase M22, glycoprotease
COG34_RS22555	COG3065	identical protein binding
COG34_RS22560	COG0318	PFAM AMP-dependent synthetase and ligase
COG34_RS22565	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
COG34_RS22570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
COG34_RS22575	COG4638	Rieske (2fe-2S)
COG34_RS22580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
COG34_RS22585	COG0473	3-isopropylmalate dehydrogenase activity
COG34_RS22590	COG0583	DNA-binding transcription factor activity
COG34_RS22600	COG3615	Tellurite resistance protein tehB
COG34_RS22615	COG0675	Transposase, IS605 OrfB family
COG34_RS22620	COG2261	transglycosylase associated protein
COG34_RS22635	COG2203	Gaf domain
COG34_RS22635	COG2199	diguanylate cyclase activity
COG34_RS22640	COG3042	response to heat
COG34_RS22645	COG3189	MarR family transcriptional regulator
COG34_RS22650	COG2807	transmembrane transport
COG34_RS22655	COG2207	Transcriptional regulator
COG34_RS22670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COG34_RS22675	COG2199	diguanylate cyclase activity
COG34_RS22680	COG2199	diguanylate cyclase activity
COG34_RS22690	COG2766	serine protein kinase
COG34_RS22695	COG3713	MltA-interacting MipA family protein
COG34_RS22700	COG0656	L-ascorbic acid biosynthetic process
COG34_RS22705	COG0676	glucose-6-phosphate 1-epimerase activity
COG34_RS22710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
COG34_RS22720	COG3139	Protein of unknown function (DUF1315)
COG34_RS22725	COG1335	isochorismatase
COG34_RS22730	COG0252	asparaginase activity
COG34_RS22735	COG0616	signal peptide processing
COG34_RS22745	COG0778	Nitroreductase
COG34_RS22760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COG34_RS22770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
COG34_RS22780	COG0494	nUDIX hydrolase
COG34_RS22785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COG34_RS22790	COG2897	thiosulfate sulfurtransferase activity
COG34_RS22795	COG4136	ATPase activity
COG34_RS22800	COG4135	transport system, permease component
COG34_RS22805	COG4134	Bacterial extracellular solute-binding protein
COG34_RS22810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COG34_RS22815	COG0398	Pfam SNARE associated Golgi protein
COG34_RS22825	COG0398	Pfam SNARE associated Golgi protein
COG34_RS22830	COG0708	Exodeoxyribonuclease III
COG34_RS22865	COG3678	ATP-independent chaperone mediated protein folding
COG34_RS22875	COG0322	excinuclease ABC activity
COG34_RS22885	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COG34_RS22895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
COG34_RS22900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
COG34_RS22905	COG1447	Phosphotransferase system cellobiose-specific component IIA
COG34_RS22910	COG2169	Transcriptional regulator
COG34_RS22910	COG1917	Cupin 2, conserved barrel domain protein
COG34_RS22915	COG1486	melibiose metabolic process
COG34_RS22925	COG0753	catalase activity
COG34_RS22945	COG1823	symporter activity
COG34_RS22950	COG1988	membrane-bound metal-dependent
COG34_RS22955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
COG34_RS22965	COG3001	Fructosamine kinase
COG34_RS22975	COG1105	Belongs to the carbohydrate kinase PfkB family
COG34_RS22980	COG3137	Salt-induced outer membrane protein
COG34_RS23040	COG0386	Belongs to the glutathione peroxidase family
COG34_RS23050	COG0791	NLP P60 protein
COG34_RS23055	COG2200	EAL domain
COG34_RS23065	COG4256	Hemin uptake protein
COG34_RS23070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
COG34_RS23085	COG0574	Belongs to the PEP-utilizing enzyme family
COG34_RS23085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COG34_RS23090	COG0318	PFAM AMP-dependent synthetase and ligase
COG34_RS23095	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
COG34_RS23100	COG0644	oxidoreductase
COG34_RS23105	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
COG34_RS23110	COG2086	electron transfer activity
COG34_RS23120	COG2207	Transcriptional regulator
COG34_RS23120	COG1917	Cupin 2, conserved barrel domain protein
COG34_RS23125	COG1960	acyl-CoA dehydrogenase activity
COG34_RS23130	COG4670	ketone body catabolic process
COG34_RS23145	COG2271	Major facilitator Superfamily
COG34_RS23150	COG0738	Major facilitator superfamily
COG34_RS23165	COG0628	permease
COG34_RS23175	COG0277	FAD linked oxidase domain protein
COG34_RS23175	COG0247	lactate metabolic process
COG34_RS23180	COG2050	protein possibly involved in aromatic compounds catabolism
COG34_RS23190	COG0316	Belongs to the HesB IscA family
COG34_RS23195	COG0719	Fe-S assembly protein
COG34_RS23200	COG0396	ATPase activity
COG34_RS23205	COG0719	Fe-S assembly protein
COG34_RS23220	COG1376	ErfK ybiS ycfS ynhG family protein
COG34_RS23225	COG4238	major outer membrane lipoprotein
COG34_RS23230	COG0469	pyruvate kinase activity
COG34_RS23240	COG0437	4 iron, 4 sulfur cluster binding
COG34_RS23245	COG2414	aldehyde ferredoxin oxidoreductase
COG34_RS23255	COG0437	4 iron, 4 sulfur cluster binding
COG34_RS23260	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
COG34_RS23270	COG4529	Protein conserved in bacteria
COG34_RS23290	COG3468	outer membrane autotransporter barrel domain protein
COG34_RS23300	COG0307	riboflavin synthase, alpha
COG34_RS23305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
COG34_RS23310	COG2814	Major facilitator Superfamily
COG34_RS23315	COG0583	DNA-binding transcription factor activity
COG34_RS23335	COG2814	Major facilitator Superfamily
COG34_RS23340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
COG34_RS23345	COG0791	NLP P60 protein
COG34_RS23350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
COG34_RS23355	COG1201	RNA secondary structure unwinding
COG34_RS23365	COG0346	lactoylglutathione lyase activity
COG34_RS23370	COG1902	pentaerythritol trinitrate reductase activity
COG34_RS23375	COG1309	transcriptional regulator
COG34_RS23380	COG3313	Fe-S protein
COG34_RS23385	COG4989	oxidoreductase activity
COG34_RS23390	COG2032	superoxide dismutase activity
COG34_RS23395	COG1289	transmembrane transporter activity
COG34_RS23400	COG1566	PFAM secretion protein HlyD family protein
COG34_RS23415	COG3133	Outer membrane lipoprotein
COG34_RS23425	COG3895	Periplasmic Protein
COG34_RS23440	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
COG34_RS23445	COG0625	glutathione transferase activity
COG34_RS23450	COG3104	oligopeptide transport
COG34_RS23460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COG34_RS23470	COG4659	FMN binding
COG34_RS23515	COG0673	inositol 2-dehydrogenase activity
COG34_RS23525	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
COG34_RS23530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
COG34_RS23530	COG1263	PTS System
COG34_RS23535	COG1609	Transcriptional regulator
COG34_RS23540	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS23545	COG1309	transcriptional regulator
COG34_RS23550	COG3250	beta-galactosidase activity
COG34_RS23565	COG5339	Protein conserved in bacteria
COG34_RS23570	COG1482	cell wall glycoprotein biosynthetic process
COG34_RS23575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
COG34_RS23575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
COG34_RS23580	COG0114	fumarate hydratase activity
COG34_RS23590	COG2205	protein histidine kinase activity
COG34_RS23595	COG0745	RESPONSE REGULATOR receiver
COG34_RS23600	COG3136	membrane protein required for alginate biosynthesis
COG34_RS23610	COG0531	amino acid
COG34_RS23625	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
COG34_RS23630	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
COG34_RS23635	COG0628	permease
COG34_RS23655	COG3591	Belongs to the peptidase S1B family
COG34_RS23675	COG2814	Major facilitator Superfamily
COG34_RS23680	COG0583	DNA-binding transcription factor activity
COG34_RS23685	COG1940	carbohydrate kinase activity
COG34_RS23690	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
COG34_RS23700	COG3381	protein complex oligomerization
COG34_RS23705	COG3302	dmso reductase anchor subunit
COG34_RS23710	COG0437	4 iron, 4 sulfur cluster binding
COG34_RS23715	COG0243	molybdopterin cofactor binding
COG34_RS23720	COG0243	molybdopterin cofactor binding
COG34_RS23735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COG34_RS23755	COG4948	Mandelate Racemase Muconate Lactonizing
COG34_RS23760	COG1063	alcohol dehydrogenase
COG34_RS23770	COG0582	viral genome integration into host DNA
COG34_RS23780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
COG34_RS23855	COG1403	HNH endonuclease
COG34_RS23860	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
COG34_RS23865	COG0484	heat shock protein binding
COG34_RS23895	COG3064	Membrane
COG34_RS23915	COG3772	lysozyme
COG34_RS23925	COG1278	Cold shock
COG34_RS23990	COG0740	serine-type endopeptidase activity
COG34_RS24065	COG5301	cellulose 1,4-beta-cellobiosidase activity
COG34_RS24070	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
COG34_RS24080	COG0477	Major facilitator Superfamily
COG34_RS24085	COG0246	Mannitol dehydrogenase
COG34_RS24095	COG1802	Transcriptional regulator
COG34_RS24100	COG4221	oxidoreductase activity
COG34_RS24110	COG0339	signal peptide processing
COG34_RS24120	COG1546	Belongs to the CinA family
COG34_RS24125	COG3111	PFAM Bacterial OB fold (BOF) protein
COG34_RS24130	COG3706	GGDEF domain
COG34_RS24140	COG2814	Major facilitator Superfamily
COG34_RS24145	COG0697	spore germination
COG34_RS24150	COG2188	Transcriptional regulator
COG34_RS24160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
COG34_RS24165	COG1447	Phosphotransferase system cellobiose-specific component IIA
COG34_RS24185	COG4977	sequence-specific DNA binding
COG34_RS24190	COG1846	Transcriptional regulator
COG34_RS24215	COG0583	DNA-binding transcription factor activity
COG34_RS24220	COG1012	belongs to the aldehyde dehydrogenase family
COG34_RS24225	COG2066	Belongs to the glutaminase family
COG34_RS24240	COG2199	diguanylate cyclase activity
COG34_RS24260	COG3781	membrane
COG34_RS24310	COG2911	Protein conserved in bacteria
COG34_RS24310	COG3210	domain, Protein
COG34_RS24315	COG1396	sequence-specific DNA binding
COG34_RS24320	COG3550	peptidyl-serine autophosphorylation
COG34_RS24340	COG3539	Fimbrial protein
COG34_RS24350	COG3188	usher protein
COG34_RS24355	COG3539	Fimbrial protein
COG34_RS24360	COG3539	Fimbrial protein
COG34_RS24365	COG3539	Fimbrial protein
COG34_RS24370	COG0243	molybdopterin cofactor binding
COG34_RS24385	COG3119	arylsulfatase activity
COG34_RS24395	COG4178	(ABC) transporter
COG34_RS24400	COG4771	TonB-dependent receptor
COG34_RS24405	COG0612	Peptidase, M16
COG34_RS24410	COG0076	glutamate decarboxylase activity
COG34_RS24415	COG0531	amino acid
COG34_RS24420	COG1649	PFAM Uncharacterised BCR, COG1649
COG34_RS24430	COG2199	diguanylate cyclase activity
COG34_RS24430	COG2200	EAL domain
COG34_RS24430	COG2202	Pas domain
COG34_RS24435	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
COG34_RS24440	COG0747	negative chemotaxis
COG34_RS24445	COG0601	transmembrane transport
COG34_RS24450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
COG34_RS24455	COG0444	Belongs to the ABC transporter superfamily
COG34_RS24460	COG4608	Belongs to the ABC transporter superfamily
COG34_RS24465	COG1764	response to oxidative stress
COG34_RS24490	COG1064	alcohol dehydrogenase
COG34_RS24495	COG3093	addiction module antidote protein HigA
COG34_RS24500	COG2864	formate dehydrogenase
COG34_RS24505	COG0437	4 iron, 4 sulfur cluster binding
COG34_RS24515	COG0697	spore germination
COG34_RS24520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
COG34_RS24525	COG4886	Leucine-rich repeat (LRR) protein
COG34_RS24530	COG2223	nitrite transmembrane transporter activity
COG34_RS24535	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COG34_RS24540	COG1140	nitrate reductase beta subunit
COG34_RS24545	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
COG34_RS24550	COG2181	nitrate reductase activity
COG34_RS24555	COG0384	phenazine biosynthesis protein PhzF
COG34_RS24560	COG2162	N-hydroxyarylamine O-acetyltransferase activity
COG34_RS24565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
COG34_RS24590	COG4372	Transposase
COG34_RS24595	COG3436	PFAM IS66 Orf2 family protein
COG34_RS24605	COG4372	Transposase
COG34_RS24610	COG3436	PFAM IS66 Orf2 family protein
COG34_RS24660	COG3209	COG3209 Rhs family protein
COG34_RS24675	COG0625	glutathione transferase activity
COG34_RS24680	COG1113	amino acid transport
COG34_RS24685	COG3391	amine dehydrogenase activity
COG34_RS24700	COG4772	TonB-dependent receptor
COG34_RS24705	COG1802	Transcriptional regulator
COG34_RS24710	COG2130	NADP-dependent
COG34_RS24720	COG1247	-acetyltransferase
COG34_RS24725	COG3238	Protein conserved in bacteria
COG34_RS24755	COG1177	transmembrane transport
COG34_RS24760	COG1176	ABC-type spermidine putrescine transport system, permease component I
COG34_RS24765	COG3842	ATPase activity
COG34_RS24785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
COG34_RS24790	COG1598	PFAM Uncharacterised protein family UPF0150
COG34_RS24795	COG1724	mRNA binding
COG34_RS24805	COG0826	peptidase U32
COG34_RS24810	COG1396	sequence-specific DNA binding
COG34_RS24815	COG3135	benzoate transporter
COG34_RS24820	COG0675	Transposase, IS605 OrfB family
COG34_RS24835	COG0500	methyltransferase
COG34_RS24840	COG1275	C4-dicarboxylate transporter malic acid transport protein
COG34_RS24845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
COG34_RS24850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COG34_RS24855	COG2841	Protein conserved in bacteria
COG34_RS24875	COG5383	Protein conserved in bacteria
COG34_RS24880	COG0583	DNA-binding transcription factor activity
COG34_RS24885	COG0840	transmembrane signaling receptor activity
COG34_RS24900	COG3038	cytochrome b561
COG34_RS24905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
COG34_RS24910	COG1012	belongs to the aldehyde dehydrogenase family
COG34_RS24915	COG1434	Gram-negative-bacterium-type cell wall biogenesis
COG34_RS24920	COG1643	Atp-dependent helicase
COG34_RS24930	COG2453	phosphatase
COG34_RS24930	COG0671	phosphoesterase, PA-phosphatase related
COG34_RS24935	COG2267	carboxylic ester hydrolase activity
COG34_RS24940	COG4589	Belongs to the CDS family
COG34_RS24945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COG34_RS24955	COG0667	Aldo Keto reductase
COG34_RS24960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
COG34_RS24965	COG3327	negative regulation of DNA-templated transcription, initiation
COG34_RS24970	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
COG34_RS24975	COG0183	Belongs to the thiolase family
COG34_RS24980	COG2050	protein possibly involved in aromatic compounds catabolism
COG34_RS24985	COG1250	3-hydroxyacyl-CoA dehydrogenase
COG34_RS24990	COG1024	Enoyl-CoA hydratase
COG34_RS24995	COG1024	Enoyl-CoA hydratase
COG34_RS25000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
COG34_RS25005	COG2151	metal-sulfur cluster biosynthetic enzyme
COG34_RS25010	COG3396	Phenylacetate-CoA oxygenase
COG34_RS25015	COG3460	Phenylacetate-CoA oxygenase
COG34_RS25020	COG3396	Phenylacetate-CoA oxygenase
COG34_RS25025	COG1012	belongs to the aldehyde dehydrogenase family
COG34_RS25025	COG2030	dehydratase
COG34_RS25030	COG3733	amine oxidase
COG34_RS25035	COG1012	belongs to the aldehyde dehydrogenase family
COG34_RS25040	COG2207	Transcriptional regulator
COG34_RS25045	COG3784	Protein of unknown function (DUF1318)
COG34_RS25055	COG2911	Protein conserved in bacteria
COG34_RS25060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COG34_RS25065	COG3187	Heat shock protein
COG34_RS25070	COG3042	response to heat
COG34_RS25075	COG0674	pyruvate-flavodoxin oxidoreductase activity
COG34_RS25075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
COG34_RS25075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
COG34_RS25075	COG1013	pyruvate-flavodoxin oxidoreductase activity
COG34_RS25080	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
COG34_RS25085	COG0589	response to stress
COG34_RS25095	COG0513	Belongs to the DEAD box helicase family
COG34_RS25110	COG3706	GGDEF domain
COG34_RS25115	COG2840	Smr protein MutS2
COG34_RS25125	COG0583	DNA-binding transcription factor activity
COG34_RS25130	COG1473	amidohydrolase
COG34_RS25135	COG1473	amidohydrolase
COG34_RS25150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COG34_RS25155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
COG34_RS25160	COG0589	response to stress
COG34_RS25165	COG3182	Iron-regulated membrane protein
COG34_RS25170	COG0668	transmembrane transport
COG34_RS25175	COG4166	transmembrane transport
COG34_RS25180	COG0583	DNA-binding transcription factor activity
COG34_RS25185	COG1073	alpha beta
COG34_RS25190	COG0702	epimerase
COG34_RS25195	COG2866	Carboxypeptidase
COG34_RS25200	COG4948	Mandelate Racemase Muconate Lactonizing
COG34_RS25205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COG34_RS25210	COG3283	Transcriptional regulator of aromatic amino acids metabolism
COG34_RS25220	COG3106	COG3106 Predicted ATPase
COG34_RS25225	COG1609	Transcriptional regulator
COG34_RS25235	COG3842	ATPase activity
COG34_RS25240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
COG34_RS25245	COG1554	hydrolase, family 65, central catalytic
COG34_RS25250	COG0673	inositol 2-dehydrogenase activity
COG34_RS25255	COG1082	Xylose isomerase domain protein TIM barrel
COG34_RS25260	COG1063	alcohol dehydrogenase
COG34_RS25265	COG0395	ABC-type sugar transport system, permease component
COG34_RS25270	COG1175	transmembrane transport
COG34_RS25275	COG1653	transport
COG34_RS25285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COG34_RS25295	COG1983	PspC domain protein
COG34_RS25305	COG1842	Phage shock protein A
COG34_RS25310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
COG34_RS25315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COG34_RS25320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
COG34_RS25325	COG1012	belongs to the aldehyde dehydrogenase family
COG34_RS25335	COG1396	sequence-specific DNA binding
COG34_RS25335	COG1917	Cupin 2, conserved barrel domain protein
COG34_RS25340	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
COG34_RS25345	COG0174	glutamine synthetase
COG34_RS25365	COG4166	transmembrane transport
COG34_RS25370	COG4168	peptide transport system, permease
COG34_RS25375	COG4171	peptide transport system, permease
COG34_RS25380	COG4172	Belongs to the ABC transporter superfamily
COG34_RS25385	COG4172	Belongs to the ABC transporter superfamily
COG34_RS25390	COG2852	Protein conserved in bacteria
COG34_RS25400	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
COG34_RS25405	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COG34_RS25405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COG34_RS25420	COG5001	Diguanylate cyclase
COG34_RS25430	COG1349	DNA-binding transcription factor activity
COG34_RS25440	COG0023	Translation Initiation Factor
COG34_RS25450	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
COG34_RS25455	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
COG34_RS25460	COG0671	phosphoesterase, PA-phosphatase related
COG34_RS25470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
COG34_RS25490	COG0583	DNA-binding transcription factor activity
COG34_RS25500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COG34_RS25515	COG0616	signal peptide processing
COG34_RS25520	COG1028	Short-chain dehydrogenase reductase Sdr
COG34_RS25525	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
COG34_RS25530	COG1187	pseudouridine synthase activity
COG34_RS25535	COG0009	L-threonylcarbamoyladenylate synthase
COG34_RS25540	COG0613	PHP domain protein
COG34_RS25550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COG34_RS25555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COG34_RS25555	COG0512	Glutamine amidotransferase of anthranilate synthase
COG34_RS25560	COG0134	indole-3-glycerol-phosphate synthase activity
COG34_RS25560	COG0135	phosphoribosylanthranilate isomerase activity
COG34_RS25575	COG3729	General stress protein
COG34_RS25580	COG3685	Protein conserved in bacteria
COG34_RS25585	COG3685	Protein conserved in bacteria
COG34_RS25590	COG3047	cAMP biosynthetic process
COG34_RS25610	COG1607	acyl-coa hydrolase
COG34_RS25615	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
COG34_RS25620	COG2350	Protein conserved in bacteria
COG34_RS25625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
COG34_RS25645	COG4608	Belongs to the ABC transporter superfamily
COG34_RS25650	COG0444	Belongs to the ABC transporter superfamily
COG34_RS25655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
COG34_RS25660	COG0601	transmembrane transport
COG34_RS25665	COG4166	transmembrane transport
COG34_RS25675	COG2095	MarC family integral membrane protein
COG34_RS25680	COG1454	alcohol dehydrogenase
COG34_RS25680	COG1012	belongs to the aldehyde dehydrogenase family
COG34_RS25685	COG1435	thymidine kinase activity
COG34_RS25695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
COG34_RS25700	COG0745	RESPONSE REGULATOR receiver
COG34_RS25705	COG1752	Esterase of the alpha-beta hydrolase superfamily
COG34_RS25715	COG0788	formyltetrahydrofolate deformylase activity
COG34_RS25735	COG2181	nitrate reductase activity
COG34_RS25740	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
COG34_RS25745	COG1140	nitrate reductase beta subunit
COG34_RS25750	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COG34_RS25755	COG2223	nitrite transmembrane transporter activity
COG34_RS25765	COG3850	Histidine kinase
COG34_RS25770	COG2197	response regulator
COG34_RS25775	COG4932	domain protein
COG34_RS25780	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
COG34_RS25785	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
COG34_RS25790	COG4572	Cation transport regulator
COG34_RS25795	COG0387	Pfam Sodium calcium exchanger
COG34_RS25820	COG2912	Transglutaminase-like superfamily
COG34_RS25825	COG3094	Invasion gene expression up-regulator, SirB
COG34_RS25830	COG2890	protein-(glutamine-N5) methyltransferase activity
COG34_RS25835	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
COG34_RS25860	COG4372	Transposase
COG34_RS25865	COG3436	PFAM IS66 Orf2 family protein
COG34_RS25885	COG4584	PFAM Integrase catalytic
COG34_RS25930	COG1136	(ABC) transporter
COG34_RS25965	COG1484	DNA-dependent DNA replication
COG34_RS25985	COG3436	PFAM IS66 Orf2 family protein
COG34_RS25995	COG3039	Transposase
COG34_RS26050	COG1475	DNA binding
COG34_RS26140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
COG34_RS26325	COG4372	Transposase
COG34_RS26330	COG3436	PFAM IS66 Orf2 family protein
COG34_RS26455	COG3609	addiction module antidote protein, CC2985 family
COG34_RS26635	COG3436	PFAM IS66 Orf2 family protein
COG34_RS26640	COG4372	Transposase
COG34_RS26795	COG2831	hemolysin activation secretion protein