locus-tag	class	description
DXE54_RS00015	COG2274	protein secretion by the type I secretion system
DXE54_RS00085	COG3436	PFAM IS66 Orf2 family protein
DXE54_RS00180	COG3436	PFAM IS66 Orf2 family protein
DXE54_RS00350	COG1585	Membrane protein implicated in regulation of membrane protease activity
DXE54_RS00360	COG3468	outer membrane autotransporter barrel domain protein
DXE54_RS00375	COG1585	Membrane protein implicated in regulation of membrane protease activity
DXE54_RS00385	COG3436	PFAM IS66 Orf2 family protein
DXE54_RS00405	COG3436	PFAM IS66 Orf2 family protein
DXE54_RS00410	COG4372	Transposase
DXE54_RS00420	COG1560	Kdo2-lipid A biosynthetic process
DXE54_RS00425	COG2194	sulfuric ester hydrolase activity
DXE54_RS00430	COG0297	glycogen (starch) synthase activity
DXE54_RS00435	COG0726	polysaccharide deacetylase
DXE54_RS00450	COG0527	aspartate kinase activity
DXE54_RS00450	COG0460	homoserine dehydrogenase
DXE54_RS00460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DXE54_RS00475	COG1115	amino acid carrier protein
DXE54_RS00480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DXE54_RS00485	COG0521	Mo-molybdopterin cofactor biosynthetic process
DXE54_RS00490	COG1584	GPR1 FUN34 yaaH family protein
DXE54_RS00495	COG4735	regulation of single-species biofilm formation
DXE54_RS00525	COG0583	DNA-binding transcription factor activity
DXE54_RS00540	COG3121	Chaperone
DXE54_RS00565	COG0196	riboflavin kinase activity
DXE54_RS00580	COG1047	Peptidyl-prolyl cis-trans
DXE54_RS00600	COG0505	Belongs to the CarA family
DXE54_RS00605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DXE54_RS00655	COG0644	oxidoreductase
DXE54_RS00660	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DXE54_RS00665	COG2271	Major facilitator Superfamily
DXE54_RS00680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DXE54_RS00715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DXE54_RS00725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DXE54_RS00730	COG1357	PFAM Pentapeptide repeats (8 copies)
DXE54_RS00740	COG0564	pseudouridine synthase activity
DXE54_RS00750	COG0417	DNA replication proofreading
DXE54_RS00755	COG0235	Class ii aldolase
DXE54_RS00765	COG1069	ribulokinase activity
DXE54_RS00770	COG4977	sequence-specific DNA binding
DXE54_RS00775	COG0586	Pfam SNARE associated Golgi protein
DXE54_RS00785	COG1178	ABC-type Fe3 transport system permease component
DXE54_RS00790	COG4143	(ABC) transporter
DXE54_RS00835	COG0583	DNA-binding transcription factor activity
DXE54_RS00845	COG0028	Belongs to the TPP enzyme family
DXE54_RS00850	COG0440	acetolactate synthase activity
DXE54_RS00860	COG1609	Transcriptional regulator
DXE54_RS00875	COG3116	cell division
DXE54_RS00880	COG0768	penicillin binding
DXE54_RS00885	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DXE54_RS00890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DXE54_RS00900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DXE54_RS00905	COG0772	Belongs to the SEDS family
DXE54_RS00920	COG1181	Belongs to the D-alanine--D-alanine ligase family
DXE54_RS00925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DXE54_RS00930	COG0849	cell division
DXE54_RS00935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DXE54_RS00955	COG0494	nUDIX hydrolase
DXE54_RS00970	COG0237	dephospho-CoA kinase activity
DXE54_RS00985	COG1459	type II secretion system
DXE54_RS00990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DXE54_RS00995	COG4969	Belongs to the N-Me-Phe pilin family
DXE54_RS01000	COG0157	Belongs to the NadC ModD family
DXE54_RS01005	COG3023	N-Acetylmuramoyl-L-alanine amidase
DXE54_RS01010	COG3725	Membrane protein required for beta-lactamase induction
DXE54_RS01020	COG2186	Transcriptional regulator
DXE54_RS01025	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DXE54_RS01030	COG0508	dehydrogenase complex catalyzes the overall conversion of
DXE54_RS01035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DXE54_RS01040	COG3064	Membrane
DXE54_RS01045	COG1049	propionate catabolic process, 2-methylcitrate cycle
DXE54_RS01070	COG2132	Multicopper oxidase
DXE54_RS01075	COG4993	Dehydrogenase
DXE54_RS01080	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DXE54_RS01085	COG0288	reversible hydration of carbon dioxide
DXE54_RS01090	COG1131	(ABC) transporter
DXE54_RS01095	COG0842	Transport permease protein
DXE54_RS01100	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS01105	COG0726	polysaccharide deacetylase
DXE54_RS01115	COG5464	transposase or invertase
DXE54_RS01145	COG3539	Fimbrial protein
DXE54_RS01150	COG3539	Fimbrial protein
DXE54_RS01155	COG3188	usher protein
DXE54_RS01160	COG3121	Chaperone
DXE54_RS01170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DXE54_RS01175	COG0617	tRNA 3'-terminal CCA addition
DXE54_RS01180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DXE54_RS01185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DXE54_RS01195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DXE54_RS01200	COG1643	Atp-dependent helicase
DXE54_RS01205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXE54_RS01210	COG4774	siderophore transport
DXE54_RS01215	COG1120	ATPase activity
DXE54_RS01220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DXE54_RS01225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXE54_RS01250	COG2860	membrane
DXE54_RS01255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DXE54_RS01270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXE54_RS01275	COG3835	regulator
DXE54_RS01285	COG1408	metallophosphoesterase
DXE54_RS01300	COG0024	Methionine aminopeptidase
DXE54_RS01325	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DXE54_RS01330	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DXE54_RS01335	COG0575	Belongs to the CDS family
DXE54_RS01340	COG0750	zinc metalloprotease
DXE54_RS01350	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
DXE54_RS01355	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DXE54_RS01380	COG0587	DNA-directed DNA polymerase activity
DXE54_RS01390	COG1982	Orn Lys Arg decarboxylase major
DXE54_RS01395	COG0346	lactoylglutathione lyase activity
DXE54_RS01400	COG0037	tRNA processing
DXE54_RS01405	COG4568	rho-dependent transcription termination
DXE54_RS01415	COG4681	YaeQ
DXE54_RS01420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DXE54_RS01425	COG3015	lipoprotein NlpE involved in copper resistance
DXE54_RS01430	COG0791	NLP P60 protein
DXE54_RS01440	COG1720	tRNA m6t6A37 methyltransferase activity
DXE54_RS01450	COG1464	Belongs to the NlpA lipoprotein family
DXE54_RS01455	COG2011	ABC-type metal ion transport system permease component
DXE54_RS01460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DXE54_RS01465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DXE54_RS01500	COG0656	L-ascorbic acid biosynthetic process
DXE54_RS01505	COG0583	DNA-binding transcription factor activity
DXE54_RS01520	COG0741	lytic transglycosylase activity
DXE54_RS01520	COG1388	LysM domain
DXE54_RS01530	COG2226	methyltransferase
DXE54_RS01540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXE54_RS01565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DXE54_RS01575	COG1960	acyl-CoA dehydrogenase activity
DXE54_RS01585	COG0121	glutamine amidotransferase
DXE54_RS01590	COG3034	peptidoglycan biosynthetic process
DXE54_RS01595	COG0791	NLP P60 protein
DXE54_RS01620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DXE54_RS01625	COG0454	-acetyltransferase
DXE54_RS01635	COG3547	Transposase (IS116 IS110 IS902 family)
DXE54_RS01645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DXE54_RS01650	COG2195	Cleaves the N-terminal amino acid of tripeptides
DXE54_RS01670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DXE54_RS01690	COG0583	DNA-binding transcription factor activity
DXE54_RS01695	COG4221	oxidoreductase activity
DXE54_RS01705	COG0583	DNA-binding transcription factor activity
DXE54_RS01720	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DXE54_RS01725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DXE54_RS01735	COG2080	2 iron, 2 sulfur cluster binding
DXE54_RS01745	COG3477	response to acidic pH
DXE54_RS01750	COG0727	PFAM Uncharacterised protein family (UPF0153)
DXE54_RS01755	COG3121	Chaperone
DXE54_RS01765	COG3188	usher protein
DXE54_RS01805	COG1902	pentaerythritol trinitrate reductase activity
DXE54_RS01810	COG1073	alpha beta
DXE54_RS01815	COG0583	DNA-binding transcription factor activity
DXE54_RS01825	COG0667	Aldo Keto reductase
DXE54_RS01830	COG0656	L-ascorbic acid biosynthetic process
DXE54_RS01835	COG1388	LysM domain
DXE54_RS01840	COG3708	Transcriptional regulator
DXE54_RS01840	COG2207	Transcriptional regulator
DXE54_RS01845	COG0656	L-ascorbic acid biosynthetic process
DXE54_RS01850	COG3059	membrane
DXE54_RS01860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DXE54_RS01865	COG2207	Transcriptional regulator
DXE54_RS01870	COG0247	lactate metabolic process
DXE54_RS01875	COG1139	Iron-sulfur cluster binding protein
DXE54_RS01880	COG1556	Lactate utilization protein
DXE54_RS01890	COG3468	outer membrane autotransporter barrel domain protein
DXE54_RS01915	COG2771	luxR family
DXE54_RS01915	COG2200	EAL domain
DXE54_RS01920	COG0582	viral genome integration into host DNA
DXE54_RS01945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DXE54_RS01955	COG2771	luxR family
DXE54_RS01955	COG2200	EAL domain
DXE54_RS01960	COG0583	DNA-binding transcription factor activity
DXE54_RS01970	COG0666	response to abiotic stimulus
DXE54_RS01975	COG0666	response to abiotic stimulus
DXE54_RS01985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DXE54_RS01990	COG1304	FMN binding
DXE54_RS02000	COG0549	Belongs to the carbamate kinase family
DXE54_RS02005	COG0402	S-adenosylhomocysteine deaminase activity
DXE54_RS02010	COG1064	alcohol dehydrogenase
DXE54_RS02025	COG1280	lysine exporter protein (LysE YggA)
DXE54_RS02035	COG3829	transcription factor binding
DXE54_RS02040	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DXE54_RS02045	COG0372	Belongs to the citrate synthase family
DXE54_RS02050	COG2079	MmgE PrpD family protein
DXE54_RS02055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXE54_RS02060	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DXE54_RS02065	COG0402	S-adenosylhomocysteine deaminase activity
DXE54_RS02070	COG0583	DNA-binding transcription factor activity
DXE54_RS02075	COG0288	reversible hydration of carbon dioxide
DXE54_RS02085	COG2807	transmembrane transport
DXE54_RS02090	COG0110	maltose O-acetyltransferase activity
DXE54_RS02095	COG2223	nitrite transmembrane transporter activity
DXE54_RS02100	COG3250	beta-galactosidase activity
DXE54_RS02105	COG1609	Transcriptional regulator
DXE54_RS02115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DXE54_RS02120	COG1414	Transcriptional regulator
DXE54_RS02135	COG0596	Alpha beta hydrolase
DXE54_RS02150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DXE54_RS02155	COG2814	Major facilitator Superfamily
DXE54_RS02160	COG3122	Protein conserved in bacteria
DXE54_RS02180	COG3842	ATPase activity
DXE54_RS02190	COG1840	ABC-type Fe3 transport system, periplasmic component
DXE54_RS02195	COG2271	Major facilitator Superfamily
DXE54_RS02210	COG4521	taurine ABC transporter
DXE54_RS02220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DXE54_RS02225	COG2175	clavaminate synthase activity
DXE54_RS02230	COG0113	porphobilinogen synthase activity
DXE54_RS02235	COG3468	outer membrane autotransporter barrel domain protein
DXE54_RS02240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXE54_RS02245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DXE54_RS02250	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DXE54_RS02270	COG1181	Belongs to the D-alanine--D-alanine ligase family
DXE54_RS02285	COG1785	Belongs to the alkaline phosphatase family
DXE54_RS02295	COG3706	GGDEF domain
DXE54_RS02300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DXE54_RS02320	COG4126	flavin adenine dinucleotide binding
DXE54_RS02345	COG1940	carbohydrate kinase activity
DXE54_RS02350	COG2814	Major facilitator Superfamily
DXE54_RS02355	COG0419	ATPase involved in DNA repair
DXE54_RS02360	COG0420	3'-5' exonuclease activity
DXE54_RS02365	COG0745	RESPONSE REGULATOR receiver
DXE54_RS02370	COG5002	protein histidine kinase activity
DXE54_RS02375	COG1114	Component of the transport system for branched-chain amino acids
DXE54_RS02380	COG1113	amino acid transport
DXE54_RS02385	COG0366	Alpha amylase catalytic
DXE54_RS02410	COG1862	Preprotein translocase
DXE54_RS02415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DXE54_RS02420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DXE54_RS02425	COG1403	HNH endonuclease
DXE54_RS02430	COG3248	Nucleoside-binding outer membrane protein
DXE54_RS02435	COG4238	major outer membrane lipoprotein
DXE54_RS02445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DXE54_RS02445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DXE54_RS02460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DXE54_RS02465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DXE54_RS02475	COG0667	Aldo Keto reductase
DXE54_RS02485	COG0142	geranyltranstransferase activity
DXE54_RS02500	COG0693	protein deglycase activity
DXE54_RS02505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DXE54_RS02515	COG2814	Major facilitator Superfamily
DXE54_RS02525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DXE54_RS02530	COG1845	cytochrome c oxidase, subunit III
DXE54_RS02535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DXE54_RS02540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DXE54_RS02545	COG2223	nitrite transmembrane transporter activity
DXE54_RS02550	COG3056	Lipoprotein
DXE54_RS02555	COG0271	Belongs to the BolA IbaG family
DXE54_RS02575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DXE54_RS02580	COG0776	regulation of translation
DXE54_RS02585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DXE54_RS02590	COG1555	photosystem II stabilization
DXE54_RS02595	COG0824	Thioesterase
DXE54_RS02605	COG4533	DNA binding
DXE54_RS02615	COG1522	sequence-specific DNA binding
DXE54_RS02620	COG1132	(ABC) transporter
DXE54_RS02625	COG1132	(ABC) transporter
DXE54_RS02630	COG0347	Belongs to the P(II) protein family
DXE54_RS02635	COG0004	ammonium transporteR
DXE54_RS02640	COG1946	Acyl-CoA thioesterase
DXE54_RS02645	COG3126	Type III secretion system lipoprotein chaperone (YscW)
DXE54_RS02650	COG3695	enzyme binding
DXE54_RS02660	COG5507	3-demethylubiquinone-9 3-methyltransferase
DXE54_RS02665	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DXE54_RS02675	COG0110	maltose O-acetyltransferase activity
DXE54_RS02690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DXE54_RS02695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXE54_RS02700	COG1309	transcriptional regulator
DXE54_RS02705	COG3264	Mechanosensitive ion channel
DXE54_RS02705	COG1196	nuclear chromosome segregation
DXE54_RS02715	COG3923	Primosomal replication protein n
DXE54_RS02720	COG2832	Protein of unknown function (DUF454)
DXE54_RS02730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DXE54_RS02765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXE54_RS02770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DXE54_RS02770	COG4651	solute:proton antiporter activity
DXE54_RS02775	COG2223	nitrite transmembrane transporter activity
DXE54_RS02780	COG0737	Belongs to the 5'-nucleotidase family
DXE54_RS02785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DXE54_RS02790	COG3735	TraB family
DXE54_RS02800	COG2217	Heavy metal translocating P-type atpase
DXE54_RS02805	COG2066	Belongs to the glutaminase family
DXE54_RS02810	COG0531	amino acid
DXE54_RS02840	COG0789	Transcriptional regulator
DXE54_RS02870	COG1585	Membrane protein implicated in regulation of membrane protease activity
DXE54_RS02875	COG0330	HflC and HflK could
DXE54_RS02880	COG4619	ABC transporter
DXE54_RS02885	COG0390	transport system, permease component
DXE54_RS02890	COG3118	belongs to the thioredoxin family
DXE54_RS02895	COG0300	oxidoreductase activity
DXE54_RS02900	COG2755	lipolytic protein G-D-S-L family
DXE54_RS02905	COG4181	ATPase activity
DXE54_RS02910	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DXE54_RS02920	COG0583	DNA-binding transcription factor activity
DXE54_RS02930	COG1414	Transcriptional regulator
DXE54_RS02935	COG3960	tartronate-semialdehyde synthase activity
DXE54_RS02940	COG3622	Belongs to the hyi family
DXE54_RS02945	COG2084	Dehydrogenase
DXE54_RS02950	COG1953	Uracil, thiamine, allantoin
DXE54_RS02960	COG2233	PERMEase
DXE54_RS02965	COG1929	Belongs to the glycerate kinase type-1 family
DXE54_RS02970	COG3257	ureidoglycine aminohydrolase activity
DXE54_RS02975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXE54_RS02980	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DXE54_RS02985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DXE54_RS02990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DXE54_RS03000	COG0549	Belongs to the carbamate kinase family
DXE54_RS03005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DXE54_RS03010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DXE54_RS03020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DXE54_RS03030	COG1988	membrane-bound metal-dependent
DXE54_RS03035	COG2501	S4 domain
DXE54_RS03045	COG3539	Fimbrial protein
DXE54_RS03050	COG3121	Chaperone
DXE54_RS03055	COG3188	usher protein
DXE54_RS03060	COG3539	Fimbrial protein
DXE54_RS03065	COG3539	Fimbrial protein
DXE54_RS03070	COG2197	response regulator
DXE54_RS03095	COG3772	lysozyme
DXE54_RS03115	COG4220	transposase activity
DXE54_RS03135	COG1030	water channel activity
DXE54_RS03185	COG1196	nuclear chromosome segregation
DXE54_RS03220	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS03225	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DXE54_RS03230	COG0500	methyltransferase
DXE54_RS03245	COG4571	Outer membrane protease
DXE54_RS03260	COG4783	chaperone-mediated protein folding
DXE54_RS03265	COG1215	transferase activity, transferring glycosyl groups
DXE54_RS03270	COG5002	protein histidine kinase activity
DXE54_RS03275	COG0745	RESPONSE REGULATOR receiver
DXE54_RS03280	COG1538	Outer membrane efflux protein
DXE54_RS03285	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXE54_RS03290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXE54_RS03295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DXE54_RS03300	COG1113	amino acid transport
DXE54_RS03305	COG0668	transmembrane transport
DXE54_RS03310	COG0778	Nitroreductase
DXE54_RS03315	COG2315	Protein conserved in bacteria
DXE54_RS03345	COG2977	Belongs to the P-Pant transferase superfamily
DXE54_RS03350	COG4771	TonB-dependent receptor
DXE54_RS03355	COG2382	esterase
DXE54_RS03360	COG3251	PFAM MbtH domain protein
DXE54_RS03365	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DXE54_RS03365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXE54_RS03370	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
DXE54_RS03375	COG1120	ATPase activity
DXE54_RS03380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXE54_RS03385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXE54_RS03395	COG4592	Periplasmic binding protein
DXE54_RS03400	COG1169	isochorismate synthase
DXE54_RS03405	COG1021	2,3-dihydroxybenzoate-AMP ligase
DXE54_RS03410	COG1535	isochorismatase
DXE54_RS03410	COG3433	isochorismatase activity
DXE54_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS03420	COG2050	protein possibly involved in aromatic compounds catabolism
DXE54_RS03430	COG1966	Carbon starvation protein
DXE54_RS03435	COG2879	small protein
DXE54_RS03440	COG0371	Dehydrogenase
DXE54_RS03445	COG0436	Aminotransferase
DXE54_RS03450	COG1475	DNA binding
DXE54_RS03455	COG3969	phosphoadenosine phosphosulfate
DXE54_RS03460	COG0583	DNA-binding transcription factor activity
DXE54_RS03465	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DXE54_RS03470	COG0450	alkyl hydroperoxide reductase
DXE54_RS03475	COG3634	alkyl hydroperoxide reductase activity
DXE54_RS03480	COG0589	response to stress
DXE54_RS03485	COG1063	alcohol dehydrogenase
DXE54_RS03490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DXE54_RS03495	COG3719	Belongs to the RNase T2 family
DXE54_RS03500	COG0471	metal ion transport
DXE54_RS03515	COG3051	citrate lyase alpha subunit
DXE54_RS03520	COG2301	Belongs to the HpcH HpaI aldolase family
DXE54_RS03530	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DXE54_RS03535	COG3290	protein histidine kinase activity
DXE54_RS03540	COG4565	transcriptional regulatory protein
DXE54_RS03545	COG3069	C4-dicarboxylate transmembrane transporter activity
DXE54_RS03565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DXE54_RS03570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DXE54_RS03580	COG0583	DNA-binding transcription factor activity
DXE54_RS03595	COG1686	Belongs to the peptidase S11 family
DXE54_RS03600	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DXE54_RS03605	COG0772	Belongs to the SEDS family
DXE54_RS03610	COG0768	penicillin binding
DXE54_RS03620	COG0799	negative regulation of ribosome biogenesis
DXE54_RS03625	COG0406	alpha-ribazole phosphatase activity
DXE54_RS03635	COG1466	dna polymerase III delta subunit
DXE54_RS03650	COG2888	peptidyl-tyrosine sulfation
DXE54_RS03655	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
DXE54_RS03665	COG2214	Heat shock protein DnaJ domain protein
DXE54_RS03670	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
DXE54_RS03680	COG2214	Heat shock protein DnaJ domain protein
DXE54_RS03685	COG0443	Heat shock 70 kDa protein
DXE54_RS03695	COG1126	abc transporter atp-binding protein
DXE54_RS03700	COG0765	amino acid transport
DXE54_RS03705	COG0765	amino acid transport
DXE54_RS03710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXE54_RS03715	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DXE54_RS03720	COG4535	Mg2 and Co2 transporter CorC
DXE54_RS03730	COG1702	phosphate starvation-inducible protein PhoH
DXE54_RS03740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DXE54_RS03780	COG0367	asparagine synthase
DXE54_RS03785	COG0647	UMP catabolic process
DXE54_RS03790	COG1940	carbohydrate kinase activity
DXE54_RS03790	COG1846	Transcriptional regulator
DXE54_RS03795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DXE54_RS03805	COG2190	(PTS) system
DXE54_RS03805	COG1263	PTS System
DXE54_RS03805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXE54_RS03825	COG0735	belongs to the Fur family
DXE54_RS03835	COG0716	FMN binding
DXE54_RS03845	COG0596	Alpha beta hydrolase
DXE54_RS03850	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
DXE54_RS03855	COG0033	Phosphoglucomutase
DXE54_RS03860	COG0745	RESPONSE REGULATOR receiver
DXE54_RS03865	COG2205	protein histidine kinase activity
DXE54_RS03895	COG3272	Protein of unknown function (DUF1722)
DXE54_RS03900	COG0415	Belongs to the DNA photolyase family
DXE54_RS03910	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DXE54_RS03915	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DXE54_RS03920	COG1984	allophanate hydrolase subunit 2
DXE54_RS03930	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DXE54_RS03935	COG3180	Ammonia monooxygenase
DXE54_RS03940	COG3539	Fimbrial protein
DXE54_RS03945	COG3121	Chaperone
DXE54_RS03950	COG3188	usher protein
DXE54_RS03955	COG3539	Fimbrial protein
DXE54_RS03960	COG0372	Belongs to the citrate synthase family
DXE54_RS03970	COG2009	succinate dehydrogenase
DXE54_RS03975	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DXE54_RS03980	COG1053	succinate dehydrogenase
DXE54_RS03985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DXE54_RS03990	COG0567	Dehydrogenase, E1 component
DXE54_RS03995	COG0508	dehydrogenase complex catalyzes the overall conversion of
DXE54_RS04005	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DXE54_RS04010	COG0583	DNA-binding transcription factor activity
DXE54_RS04015	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DXE54_RS04020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DXE54_RS04020	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DXE54_RS04025	COG1301	dicarboxylic acid transport
DXE54_RS04045	COG4865	methylaspartate mutase activity
DXE54_RS04055	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXE54_RS04070	COG1271	oxidase subunit
DXE54_RS04075	COG1294	oxidase, subunit
DXE54_RS04080	COG4890	Cyd operon protein YbgT
DXE54_RS04085	COG3790	cyd operon protein YbgE
DXE54_RS04090	COG0824	Thioesterase
DXE54_RS04095	COG0811	peptide transport
DXE54_RS04100	COG0848	biopolymer transport protein
DXE54_RS04105	COG3064	Membrane
DXE54_RS04115	COG2885	chlorophyll binding
DXE54_RS04120	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DXE54_RS04170	COG3201	nicotinamide mononucleotide transporter
DXE54_RS04175	COG1230	cation diffusion facilitator family transporter
DXE54_RS04185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DXE54_RS04195	COG2017	converts alpha-aldose to the beta-anomer
DXE54_RS04205	COG1085	galactose-1-phosphate uridylyltransferase
DXE54_RS04210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DXE54_RS04215	COG1119	ATPase activity
DXE54_RS04220	COG2005	Transcriptional regulator
DXE54_RS04220	COG3585	molybdate ion transport
DXE54_RS04230	COG0725	ABC transporter, periplasmic molybdate-binding protein
DXE54_RS04235	COG4149	molybdate abc transporter
DXE54_RS04245	COG0561	phosphatase activity
DXE54_RS04255	COG0583	DNA-binding transcription factor activity
DXE54_RS04275	COG0471	metal ion transport
DXE54_RS04280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DXE54_RS04285	COG4677	pectinesterase activity
DXE54_RS04290	COG0582	viral genome integration into host DNA
DXE54_RS04340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DXE54_RS04380	COG3547	Transposase (IS116 IS110 IS902 family)
DXE54_RS04430	COG4220	transposase activity
DXE54_RS04480	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS04530	COG1881	PFAM PEBP family protein
DXE54_RS04535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DXE54_RS04550	COG2226	methyltransferase
DXE54_RS04555	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DXE54_RS04565	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DXE54_RS04575	COG0521	Mo-molybdopterin cofactor biosynthetic process
DXE54_RS04585	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DXE54_RS04590	COG0314	molybdopterin synthase activity
DXE54_RS04595	COG0670	Belongs to the BI1 family
DXE54_RS04600	COG0670	Belongs to the BI1 family
DXE54_RS04605	COG0392	lysyltransferase activity
DXE54_RS04610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DXE54_RS04615	COG3568	Endonuclease Exonuclease Phosphatase
DXE54_RS04625	COG0842	Transport permease protein
DXE54_RS04630	COG0842	Transport permease protein
DXE54_RS04635	COG1131	(ABC) transporter
DXE54_RS04645	COG1309	transcriptional regulator
DXE54_RS04650	COG0513	Belongs to the DEAD box helicase family
DXE54_RS04660	COG1199	ATP-dependent helicase activity
DXE54_RS04665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DXE54_RS04670	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DXE54_RS04680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DXE54_RS04690	COG4774	siderophore transport
DXE54_RS04705	COG0668	transmembrane transport
DXE54_RS04710	COG1126	abc transporter atp-binding protein
DXE54_RS04715	COG0765	amino acid transport
DXE54_RS04720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXE54_RS04730	COG5006	permease, DMT superfamily
DXE54_RS04740	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DXE54_RS04745	COG2194	sulfuric ester hydrolase activity
DXE54_RS04755	COG1321	iron dependent repressor
DXE54_RS04760	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DXE54_RS04765	COG1376	ErfK ybiS ycfS ynhG family protein
DXE54_RS04770	COG0488	(ABC) transporter
DXE54_RS04780	COG0561	phosphatase activity
DXE54_RS04785	COG1882	Formate acetyltransferase
DXE54_RS04790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DXE54_RS04795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DXE54_RS04800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DXE54_RS04805	COG0303	'Molybdopterin
DXE54_RS04810	COG1446	asparaginase
DXE54_RS04820	COG0747	negative chemotaxis
DXE54_RS04835	COG2200	EAL domain
DXE54_RS04840	COG2199	diguanylate cyclase activity
DXE54_RS04855	COG2133	pyrroloquinoline quinone binding
DXE54_RS04860	COG0625	glutathione transferase activity
DXE54_RS04865	COG1686	Belongs to the peptidase S11 family
DXE54_RS04870	COG1349	DNA-binding transcription factor activity
DXE54_RS04875	COG0671	phosphoesterase, PA-phosphatase related
DXE54_RS04880	COG2814	Major facilitator Superfamily
DXE54_RS04890	COG0561	phosphatase activity
DXE54_RS04895	COG0738	Major facilitator superfamily
DXE54_RS04900	COG3226	Transcriptional regulator
DXE54_RS04920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DXE54_RS04930	COG0778	Nitroreductase
DXE54_RS04945	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DXE54_RS04950	COG3842	ATPase activity
DXE54_RS04960	COG1177	transmembrane transport
DXE54_RS04990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXE54_RS04995	COG4160	amino acid transport
DXE54_RS05000	COG4215	(ABC) transporter
DXE54_RS05005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXE54_RS05010	COG1126	abc transporter atp-binding protein
DXE54_RS05030	COG3023	N-Acetylmuramoyl-L-alanine amidase
DXE54_RS05035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXE54_RS05040	COG0702	epimerase
DXE54_RS05045	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DXE54_RS05050	COG0028	Belongs to the TPP enzyme family
DXE54_RS05055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DXE54_RS05065	COG2431	L-lysine efflux transmembrane transporter activity
DXE54_RS05070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DXE54_RS05075	COG3593	DNA synthesis involved in DNA repair
DXE54_RS05080	COG2990	Protein conserved in bacteria
DXE54_RS05085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXE54_RS05090	COG1136	(ABC) transporter
DXE54_RS05090	COG0577	efflux transmembrane transporter activity
DXE54_RS05095	COG1278	Cold shock
DXE54_RS05105	COG0542	response to heat
DXE54_RS05130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DXE54_RS05135	COG4988	ABC transporter
DXE54_RS05140	COG0492	ferredoxin-NADP+ reductase activity
DXE54_RS05145	COG1522	sequence-specific DNA binding
DXE54_RS05160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DXE54_RS05170	COG0243	molybdopterin cofactor binding
DXE54_RS05175	COG0437	4 iron, 4 sulfur cluster binding
DXE54_RS05180	COG3302	dmso reductase anchor subunit
DXE54_RS05185	COG1335	isochorismatase
DXE54_RS05195	COG0531	amino acid
DXE54_RS05205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DXE54_RS05210	COG1882	Formate acetyltransferase
DXE54_RS05215	COG2116	formate transmembrane transporter activity
DXE54_RS05220	COG1944	ATP diphosphatase activity
DXE54_RS05225	COG2323	membrane
DXE54_RS05240	COG0501	Belongs to the peptidase M48B family
DXE54_RS05250	COG0539	negative regulation of cytoplasmic translation
DXE54_RS05260	COG2333	competence protein COMEC
DXE54_RS05260	COG0658	competence protein
DXE54_RS05265	COG1132	(ABC) transporter
DXE54_RS05275	COG3214	Protein conserved in bacteria
DXE54_RS05290	COG3173	Aminoglycoside phosphotransferase
DXE54_RS05295	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DXE54_RS05300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DXE54_RS05310	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
DXE54_RS05320	COG2989	Protein conserved in bacteria
DXE54_RS05325	COG3108	Peptidase M15
DXE54_RS05330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DXE54_RS05335	COG1448	Aminotransferase
DXE54_RS05355	COG0308	aminopeptidase N
DXE54_RS05360	COG1116	anion transmembrane transporter activity
DXE54_RS05365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DXE54_RS05375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DXE54_RS05380	COG0431	NADPH-dependent FMN reductase
DXE54_RS05385	COG3539	Fimbrial protein
DXE54_RS05390	COG3121	Chaperone
DXE54_RS05395	COG3188	usher protein
DXE54_RS05400	COG3539	Fimbrial protein
DXE54_RS05405	COG3539	Fimbrial protein
DXE54_RS05410	COG3539	Fimbrial protein
DXE54_RS05415	COG3121	Chaperone
DXE54_RS05430	COG0633	Ferredoxin
DXE54_RS05430	COG3217	Mosc domain protein beta barrel domain protein
DXE54_RS05440	COG0488	(ABC) transporter
DXE54_RS05445	COG2995	paraquat-inducible protein a
DXE54_RS05450	COG3008	intermembrane lipid transfer
DXE54_RS05450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DXE54_RS05455	COG3009	Protein conserved in bacteria
DXE54_RS05460	COG3130	regulation of translation
DXE54_RS05470	COG1067	ATP-dependent peptidase activity
DXE54_RS05490	COG3070	regulator of competence-specific genes
DXE54_RS05495	COG1289	transmembrane transporter activity
DXE54_RS05500	COG3304	Inner membrane component domain
DXE54_RS05505	COG0210	DNA helicase
DXE54_RS05520	COG1832	CoA-binding protein
DXE54_RS05535	COG1254	Belongs to the acylphosphatase family
DXE54_RS05540	COG2920	part of a sulfur-relay system
DXE54_RS05545	COG0670	Belongs to the BI1 family
DXE54_RS05560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXE54_RS05590	COG1484	DNA-dependent DNA replication
DXE54_RS05595	COG1846	Transcriptional regulator
DXE54_RS05620	COG1403	HNH endonuclease
DXE54_RS05625	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DXE54_RS05645	COG2207	Transcriptional regulator
DXE54_RS05680	COG3772	lysozyme
DXE54_RS05710	COG4220	transposase activity
DXE54_RS05805	COG2032	superoxide dismutase activity
DXE54_RS05820	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS05860	COG3038	cytochrome b561
DXE54_RS05865	COG3443	Belongs to the bacterial solute-binding protein 9 family
DXE54_RS05880	COG2351	hydroxyisourate hydrolase activity
DXE54_RS05885	COG0745	RESPONSE REGULATOR receiver
DXE54_RS05890	COG2205	protein histidine kinase activity
DXE54_RS05900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DXE54_RS05910	COG1418	mRNA catabolic process
DXE54_RS05915	COG0270	DNA (cytosine-5-)-methyltransferase activity
DXE54_RS05920	COG3727	T/G mismatch-specific endonuclease activity
DXE54_RS05925	COG0697	spore germination
DXE54_RS05930	COG2354	Protein conserved in bacteria
DXE54_RS05935	COG5475	Uncharacterized small protein (DUF2158)
DXE54_RS05940	COG3706	GGDEF domain
DXE54_RS05960	COG2197	response regulator
DXE54_RS05965	COG1684	flagellar biosynthetic protein fliR
DXE54_RS05970	COG1987	bacterial-type flagellum assembly
DXE54_RS05975	COG1338	Plays a role in the flagellum-specific transport system
DXE54_RS05980	COG3190	flagellar
DXE54_RS05985	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DXE54_RS05990	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DXE54_RS05995	COG1580	Controls the rotational direction of flagella during chemotaxis
DXE54_RS06000	COG3144	bacterial-type flagellum assembly
DXE54_RS06005	COG2882	bacterial-type flagellum organization
DXE54_RS06010	COG1157	protein secretion by the type III secretion system
DXE54_RS06015	COG1317	bacterial-type flagellum organization
DXE54_RS06020	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DXE54_RS06025	COG1766	The M ring may be actively involved in energy transduction
DXE54_RS06040	COG0454	-acetyltransferase
DXE54_RS06045	COG2135	peptidase activity
DXE54_RS06050	COG0425	Belongs to the sulfur carrier protein TusA family
DXE54_RS06055	COG2391	methyltransferase activity
DXE54_RS06065	COG0366	Alpha amylase catalytic
DXE54_RS06075	COG1516	flagellar protein fliS
DXE54_RS06080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DXE54_RS06090	COG1191	sigma factor activity
DXE54_RS06100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXE54_RS06110	COG0765	amino acid transport
DXE54_RS06115	COG1126	abc transporter atp-binding protein
DXE54_RS06120	COG2197	response regulator
DXE54_RS06135	COG2197	response regulator
DXE54_RS06220	COG3012	SEC-C Motif Domain Protein
DXE54_RS06220	COG3318	Belongs to the UPF0149 family
DXE54_RS06230	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DXE54_RS06260	COG3012	SEC-C Motif Domain Protein
DXE54_RS06260	COG3318	Belongs to the UPF0149 family
DXE54_RS06265	COG0814	amino acid
DXE54_RS06275	COG1528	Iron-storage protein
DXE54_RS06295	COG1528	Iron-storage protein
DXE54_RS06300	COG1879	ABC-type sugar transport system periplasmic component
DXE54_RS06305	COG1129	ABC transporter
DXE54_RS06310	COG1172	Belongs to the binding-protein-dependent transport system permease family
DXE54_RS06315	COG1877	trehalose-phosphatase activity
DXE54_RS06325	COG0589	response to stress
DXE54_RS06340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DXE54_RS06345	COG1360	Flagellar Motor Protein
DXE54_RS06350	COG2198	Histidine kinase
DXE54_RS06350	COG0643	Histidine kinase
DXE54_RS06355	COG0835	chemotaxis
DXE54_RS06360	COG0840	transmembrane signaling receptor activity
DXE54_RS06370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DXE54_RS06380	COG0745	RESPONSE REGULATOR receiver
DXE54_RS06385	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DXE54_RS06390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DXE54_RS06395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DXE54_RS06405	COG3755	Protein conserved in bacteria
DXE54_RS06415	COG3102	Protein conserved in bacteria
DXE54_RS06425	COG3005	denitrification pathway
DXE54_RS06430	COG0243	molybdopterin cofactor binding
DXE54_RS06445	COG3788	relative of glutathione S-transferase, MAPEG superfamily
DXE54_RS06450	COG1801	Protein of unknown function DUF72
DXE54_RS06455	COG0582	viral genome integration into host DNA
DXE54_RS06535	COG1484	DNA-dependent DNA replication
DXE54_RS06540	COG0305	Participates in initiation and elongation during chromosome replication
DXE54_RS06550	COG1403	HNH endonuclease
DXE54_RS06620	COG3772	lysozyme
DXE54_RS06650	COG0740	serine-type endopeptidase activity
DXE54_RS06725	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS06750	COG1335	isochorismatase
DXE54_RS06760	COG0494	nUDIX hydrolase
DXE54_RS06765	COG0217	transcriptional regulatory protein
DXE54_RS06795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DXE54_RS06805	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
DXE54_RS06810	COG0739	heme binding
DXE54_RS06815	COG1560	Kdo2-lipid A biosynthetic process
DXE54_RS06820	COG0469	pyruvate kinase activity
DXE54_RS06825	COG1737	Transcriptional regulator
DXE54_RS06830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DXE54_RS06835	COG0129	dihydroxy-acid dehydratase activity
DXE54_RS06840	COG0800	Aldolase
DXE54_RS06850	COG3141	response to X-ray
DXE54_RS06860	COG2979	Protein of unknown function (DUF533)
DXE54_RS06865	COG1770	oligopeptidase
DXE54_RS06870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXE54_RS06875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DXE54_RS06885	COG2372	response to copper ion
DXE54_RS06890	COG1276	copper resistance
DXE54_RS06900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DXE54_RS06920	COG3008	intermembrane lipid transfer
DXE54_RS06925	COG2995	paraquat-inducible protein a
DXE54_RS06930	COG1956	GAF domain-containing protein
DXE54_RS06940	COG0793	Belongs to the peptidase S41A family
DXE54_RS06950	COG2814	Major facilitator Superfamily
DXE54_RS06955	COG1414	Transcriptional regulator
DXE54_RS06985	COG2226	methyltransferase
DXE54_RS07000	COG3716	PTS system mannose fructose sorbose family IID component
DXE54_RS07005	COG3715	PTS system
DXE54_RS07010	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXE54_RS07010	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS07020	COG2200	EAL domain
DXE54_RS07025	COG1760	l-serine dehydratase
DXE54_RS07035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DXE54_RS07050	COG0251	oxidation-reduction process
DXE54_RS07055	COG1199	ATP-dependent helicase activity
DXE54_RS07060	COG1214	PFAM Peptidase M22, glycoprotease
DXE54_RS07065	COG3065	identical protein binding
DXE54_RS07070	COG0318	PFAM AMP-dependent synthetase and ligase
DXE54_RS07075	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DXE54_RS07080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DXE54_RS07085	COG4638	Rieske (2fe-2S)
DXE54_RS07090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DXE54_RS07095	COG0473	3-isopropylmalate dehydrogenase activity
DXE54_RS07100	COG0583	DNA-binding transcription factor activity
DXE54_RS07110	COG3615	Tellurite resistance protein tehB
DXE54_RS07120	COG2261	transglycosylase associated protein
DXE54_RS07135	COG2199	diguanylate cyclase activity
DXE54_RS07135	COG2203	Gaf domain
DXE54_RS07140	COG3042	response to heat
DXE54_RS07145	COG3189	MarR family transcriptional regulator
DXE54_RS07150	COG2807	transmembrane transport
DXE54_RS07155	COG2207	Transcriptional regulator
DXE54_RS07170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DXE54_RS07175	COG2199	diguanylate cyclase activity
DXE54_RS07180	COG2199	diguanylate cyclase activity
DXE54_RS07190	COG2766	serine protein kinase
DXE54_RS07195	COG3713	MltA-interacting MipA family protein
DXE54_RS07200	COG0656	L-ascorbic acid biosynthetic process
DXE54_RS07205	COG0676	glucose-6-phosphate 1-epimerase activity
DXE54_RS07210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DXE54_RS07220	COG3139	Protein of unknown function (DUF1315)
DXE54_RS07225	COG1063	alcohol dehydrogenase
DXE54_RS07230	COG2271	Major facilitator Superfamily
DXE54_RS07235	COG1063	alcohol dehydrogenase
DXE54_RS07240	COG0191	fructose-bisphosphate aldolase activity
DXE54_RS07245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXE54_RS07250	COG0667	Aldo Keto reductase
DXE54_RS07255	COG1349	DNA-binding transcription factor activity
DXE54_RS07260	COG2814	Major facilitator Superfamily
DXE54_RS07265	COG1335	isochorismatase
DXE54_RS07270	COG0252	asparaginase activity
DXE54_RS07280	COG0616	signal peptide processing
DXE54_RS07285	COG0778	Nitroreductase
DXE54_RS07290	COG0709	Synthesizes selenophosphate from selenide and ATP
DXE54_RS07295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DXE54_RS07305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DXE54_RS07315	COG0494	nUDIX hydrolase
DXE54_RS07320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DXE54_RS07325	COG2897	thiosulfate sulfurtransferase activity
DXE54_RS07330	COG4136	ATPase activity
DXE54_RS07335	COG4135	transport system, permease component
DXE54_RS07340	COG4134	Bacterial extracellular solute-binding protein
DXE54_RS07345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DXE54_RS07350	COG0398	Pfam SNARE associated Golgi protein
DXE54_RS07360	COG0398	Pfam SNARE associated Golgi protein
DXE54_RS07365	COG0708	Exodeoxyribonuclease III
DXE54_RS07395	COG3678	ATP-independent chaperone mediated protein folding
DXE54_RS07405	COG0322	excinuclease ABC activity
DXE54_RS07415	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DXE54_RS07420	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DXE54_RS07430	COG1447	Phosphotransferase system cellobiose-specific component IIA
DXE54_RS07435	COG1917	Cupin 2, conserved barrel domain protein
DXE54_RS07435	COG2169	Transcriptional regulator
DXE54_RS07440	COG1486	melibiose metabolic process
DXE54_RS07450	COG0753	catalase activity
DXE54_RS07465	COG1823	symporter activity
DXE54_RS07470	COG1988	membrane-bound metal-dependent
DXE54_RS07475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXE54_RS07485	COG3001	Fructosamine kinase
DXE54_RS07495	COG1105	Belongs to the carbohydrate kinase PfkB family
DXE54_RS07500	COG3137	Salt-induced outer membrane protein
DXE54_RS07545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DXE54_RS07545	COG0072	phenylalanine-tRNA ligase activity
DXE54_RS07605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DXE54_RS07610	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS07625	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS07705	COG4695	Portal protein
DXE54_RS07790	COG4974	Belongs to the 'phage' integrase family
DXE54_RS07810	COG0386	Belongs to the glutathione peroxidase family
DXE54_RS07820	COG0791	NLP P60 protein
DXE54_RS07835	COG4256	Hemin uptake protein
DXE54_RS07840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DXE54_RS07850	COG0574	Belongs to the PEP-utilizing enzyme family
DXE54_RS07850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DXE54_RS07855	COG0318	PFAM AMP-dependent synthetase and ligase
DXE54_RS07860	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DXE54_RS07865	COG0644	oxidoreductase
DXE54_RS07870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DXE54_RS07875	COG2086	electron transfer activity
DXE54_RS07880	COG1917	Cupin 2, conserved barrel domain protein
DXE54_RS07880	COG2207	Transcriptional regulator
DXE54_RS07890	COG4670	ketone body catabolic process
DXE54_RS07905	COG2271	Major facilitator Superfamily
DXE54_RS07910	COG0738	Major facilitator superfamily
DXE54_RS07925	COG0628	permease
DXE54_RS07930	COG0277	FAD linked oxidase domain protein
DXE54_RS07930	COG0247	lactate metabolic process
DXE54_RS07935	COG2050	protein possibly involved in aromatic compounds catabolism
DXE54_RS07945	COG0316	Belongs to the HesB IscA family
DXE54_RS07950	COG0719	Fe-S assembly protein
DXE54_RS07955	COG0396	ATPase activity
DXE54_RS07960	COG0719	Fe-S assembly protein
DXE54_RS07975	COG1376	ErfK ybiS ycfS ynhG family protein
DXE54_RS07980	COG4238	major outer membrane lipoprotein
DXE54_RS07985	COG0469	pyruvate kinase activity
DXE54_RS07995	COG0437	4 iron, 4 sulfur cluster binding
DXE54_RS08000	COG2414	aldehyde ferredoxin oxidoreductase
DXE54_RS08010	COG0437	4 iron, 4 sulfur cluster binding
DXE54_RS08015	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DXE54_RS08025	COG4529	Protein conserved in bacteria
DXE54_RS08045	COG3468	outer membrane autotransporter barrel domain protein
DXE54_RS08055	COG0307	riboflavin synthase, alpha
DXE54_RS08060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DXE54_RS08065	COG2814	Major facilitator Superfamily
DXE54_RS08070	COG0583	DNA-binding transcription factor activity
DXE54_RS08085	COG2814	Major facilitator Superfamily
DXE54_RS08090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DXE54_RS08095	COG0791	NLP P60 protein
DXE54_RS08100	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DXE54_RS08105	COG1201	RNA secondary structure unwinding
DXE54_RS08115	COG0346	lactoylglutathione lyase activity
DXE54_RS08120	COG1902	pentaerythritol trinitrate reductase activity
DXE54_RS08125	COG1309	transcriptional regulator
DXE54_RS08130	COG3313	Fe-S protein
DXE54_RS08135	COG4989	oxidoreductase activity
DXE54_RS08140	COG2032	superoxide dismutase activity
DXE54_RS08145	COG1289	transmembrane transporter activity
DXE54_RS08150	COG1566	PFAM secretion protein HlyD family protein
DXE54_RS08165	COG3133	Outer membrane lipoprotein
DXE54_RS08175	COG3895	Periplasmic Protein
DXE54_RS08190	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DXE54_RS08195	COG0625	glutathione transferase activity
DXE54_RS08200	COG3104	oligopeptide transport
DXE54_RS08205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DXE54_RS08215	COG4659	FMN binding
DXE54_RS08255	COG0673	inositol 2-dehydrogenase activity
DXE54_RS08265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DXE54_RS08270	COG1263	PTS System
DXE54_RS08270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXE54_RS08275	COG1609	Transcriptional regulator
DXE54_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS08285	COG1309	transcriptional regulator
DXE54_RS08290	COG3250	beta-galactosidase activity
DXE54_RS08305	COG5339	Protein conserved in bacteria
DXE54_RS08315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DXE54_RS08315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DXE54_RS08320	COG0114	fumarate hydratase activity
DXE54_RS08330	COG2205	protein histidine kinase activity
DXE54_RS08335	COG0745	RESPONSE REGULATOR receiver
DXE54_RS08340	COG3136	membrane protein required for alginate biosynthesis
DXE54_RS08350	COG0531	amino acid
DXE54_RS08360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DXE54_RS08365	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DXE54_RS08370	COG0628	permease
DXE54_RS08385	COG3591	Belongs to the peptidase S1B family
DXE54_RS08400	COG2814	Major facilitator Superfamily
DXE54_RS08405	COG0583	DNA-binding transcription factor activity
DXE54_RS08410	COG1940	carbohydrate kinase activity
DXE54_RS08415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DXE54_RS08425	COG3381	protein complex oligomerization
DXE54_RS08430	COG3302	dmso reductase anchor subunit
DXE54_RS08435	COG0437	4 iron, 4 sulfur cluster binding
DXE54_RS08450	COG0243	molybdopterin cofactor binding
DXE54_RS08455	COG0243	molybdopterin cofactor binding
DXE54_RS08470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXE54_RS08485	COG4948	Mandelate Racemase Muconate Lactonizing
DXE54_RS08490	COG1063	alcohol dehydrogenase
DXE54_RS08500	COG0582	viral genome integration into host DNA
DXE54_RS08510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXE54_RS08540	COG1396	sequence-specific DNA binding
DXE54_RS08570	COG1846	Transcriptional regulator
DXE54_RS08660	COG1403	HNH endonuclease
DXE54_RS08665	COG0484	heat shock protein binding
DXE54_RS08725	COG3772	lysozyme
DXE54_RS08750	COG4220	transposase activity
DXE54_RS08855	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS08875	COG0589	response to stress
DXE54_RS08880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DXE54_RS08885	COG1013	pyruvate-flavodoxin oxidoreductase activity
DXE54_RS08885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXE54_RS08885	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DXE54_RS08885	COG0674	pyruvate-flavodoxin oxidoreductase activity
DXE54_RS08890	COG3042	response to heat
DXE54_RS08895	COG3187	Heat shock protein
DXE54_RS08900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DXE54_RS08905	COG2911	Protein conserved in bacteria
DXE54_RS08915	COG3784	Protein of unknown function (DUF1318)
DXE54_RS08930	COG3733	amine oxidase
DXE54_RS08935	COG1012	belongs to the aldehyde dehydrogenase family
DXE54_RS08935	COG2030	dehydratase
DXE54_RS08940	COG3396	Phenylacetate-CoA oxygenase
DXE54_RS08945	COG3460	Phenylacetate-CoA oxygenase
DXE54_RS08955	COG2151	metal-sulfur cluster biosynthetic enzyme
DXE54_RS08960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DXE54_RS08965	COG1024	Enoyl-CoA hydratase
DXE54_RS08975	COG3327	negative regulation of DNA-templated transcription, initiation
DXE54_RS08980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DXE54_RS08985	COG0667	Aldo Keto reductase
DXE54_RS08995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DXE54_RS09000	COG4589	Belongs to the CDS family
DXE54_RS09005	COG2267	carboxylic ester hydrolase activity
DXE54_RS09010	COG0671	phosphoesterase, PA-phosphatase related
DXE54_RS09010	COG2453	phosphatase
DXE54_RS09020	COG1643	Atp-dependent helicase
DXE54_RS09025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DXE54_RS09030	COG1012	belongs to the aldehyde dehydrogenase family
DXE54_RS09035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DXE54_RS09040	COG3038	cytochrome b561
DXE54_RS09055	COG0840	transmembrane signaling receptor activity
DXE54_RS09060	COG0583	DNA-binding transcription factor activity
DXE54_RS09065	COG5383	Protein conserved in bacteria
DXE54_RS09075	COG2841	Protein conserved in bacteria
DXE54_RS09080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXE54_RS09085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DXE54_RS09090	COG1275	C4-dicarboxylate transporter malic acid transport protein
DXE54_RS09095	COG0500	methyltransferase
DXE54_RS09105	COG3135	benzoate transporter
DXE54_RS09110	COG1396	sequence-specific DNA binding
DXE54_RS09115	COG0826	peptidase U32
DXE54_RS09125	COG1724	mRNA binding
DXE54_RS09130	COG1598	PFAM Uncharacterised protein family UPF0150
DXE54_RS09135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DXE54_RS09140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DXE54_RS09145	COG3842	ATPase activity
DXE54_RS09150	COG1176	ABC-type spermidine putrescine transport system, permease component I
DXE54_RS09155	COG1177	transmembrane transport
DXE54_RS09180	COG3238	Protein conserved in bacteria
DXE54_RS09185	COG1247	-acetyltransferase
DXE54_RS09190	COG2130	NADP-dependent
DXE54_RS09195	COG1802	Transcriptional regulator
DXE54_RS09200	COG4772	TonB-dependent receptor
DXE54_RS09205	COG3391	amine dehydrogenase activity
DXE54_RS09210	COG1113	amino acid transport
DXE54_RS09215	COG0625	glutathione transferase activity
DXE54_RS09265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DXE54_RS09270	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DXE54_RS09275	COG0384	phenazine biosynthesis protein PhzF
DXE54_RS09280	COG2181	nitrate reductase activity
DXE54_RS09285	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DXE54_RS09290	COG1140	nitrate reductase beta subunit
DXE54_RS09295	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DXE54_RS09300	COG2223	nitrite transmembrane transporter activity
DXE54_RS09305	COG4886	Leucine-rich repeat (LRR) protein
DXE54_RS09310	COG4886	Leucine-rich repeat (LRR) protein
DXE54_RS09320	COG0697	spore germination
DXE54_RS09330	COG0437	4 iron, 4 sulfur cluster binding
DXE54_RS09335	COG2864	formate dehydrogenase
DXE54_RS09340	COG3093	addiction module antidote protein HigA
DXE54_RS09345	COG1064	alcohol dehydrogenase
DXE54_RS09365	COG1764	response to oxidative stress
DXE54_RS09370	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS09375	COG2610	gluconate transmembrane transporter activity
DXE54_RS09380	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXE54_RS09390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DXE54_RS09395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DXE54_RS09405	COG4608	Belongs to the ABC transporter superfamily
DXE54_RS09410	COG0444	Belongs to the ABC transporter superfamily
DXE54_RS09415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXE54_RS09420	COG0601	transmembrane transport
DXE54_RS09425	COG0747	negative chemotaxis
DXE54_RS09430	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DXE54_RS09435	COG2202	Pas domain
DXE54_RS09435	COG2200	EAL domain
DXE54_RS09435	COG2199	diguanylate cyclase activity
DXE54_RS09440	COG3706	GGDEF domain
DXE54_RS09445	COG1649	PFAM Uncharacterised BCR, COG1649
DXE54_RS09450	COG0531	amino acid
DXE54_RS09455	COG0076	glutamate decarboxylase activity
DXE54_RS09460	COG0612	Peptidase, M16
DXE54_RS09465	COG4771	TonB-dependent receptor
DXE54_RS09470	COG4178	(ABC) transporter
DXE54_RS09480	COG0641	radical SAM
DXE54_RS09485	COG3119	arylsulfatase activity
DXE54_RS09500	COG0243	molybdopterin cofactor binding
DXE54_RS09505	COG3539	Fimbrial protein
DXE54_RS09510	COG3539	Fimbrial protein
DXE54_RS09515	COG3539	Fimbrial protein
DXE54_RS09520	COG3188	usher protein
DXE54_RS09530	COG3539	Fimbrial protein
DXE54_RS09540	COG3550	peptidyl-serine autophosphorylation
DXE54_RS09545	COG1396	sequence-specific DNA binding
DXE54_RS09560	COG1070	Carbohydrate kinase
DXE54_RS09570	COG1129	ABC transporter
DXE54_RS09605	COG3781	membrane
DXE54_RS09615	COG2199	diguanylate cyclase activity
DXE54_RS09625	COG2066	Belongs to the glutaminase family
DXE54_RS09630	COG1012	belongs to the aldehyde dehydrogenase family
DXE54_RS09635	COG0583	DNA-binding transcription factor activity
DXE54_RS09655	COG1846	Transcriptional regulator
DXE54_RS09660	COG4977	sequence-specific DNA binding
DXE54_RS09670	COG0697	spore germination
DXE54_RS09675	COG2814	Major facilitator Superfamily
DXE54_RS09685	COG3706	GGDEF domain
DXE54_RS09695	COG1546	Belongs to the CinA family
DXE54_RS09700	COG0339	signal peptide processing
DXE54_RS09705	COG4221	oxidoreductase activity
DXE54_RS09710	COG1802	Transcriptional regulator
DXE54_RS09720	COG0246	Mannitol dehydrogenase
DXE54_RS09770	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS09855	COG1030	water channel activity
DXE54_RS09875	COG4220	transposase activity
DXE54_RS10030	COG1846	Transcriptional regulator
DXE54_RS10035	COG1484	DNA-dependent DNA replication
DXE54_RS10040	COG3756	Protein conserved in bacteria
DXE54_RS10090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXE54_RS10115	COG0582	viral genome integration into host DNA
DXE54_RS10125	COG0513	Belongs to the DEAD box helicase family
DXE54_RS10135	COG3706	GGDEF domain
DXE54_RS10140	COG2840	Smr protein MutS2
DXE54_RS10145	COG0583	DNA-binding transcription factor activity
DXE54_RS10150	COG1473	amidohydrolase
DXE54_RS10155	COG1473	amidohydrolase
DXE54_RS10160	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DXE54_RS10165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DXE54_RS10170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXE54_RS10175	COG0589	response to stress
DXE54_RS10180	COG3182	Iron-regulated membrane protein
DXE54_RS10185	COG0668	transmembrane transport
DXE54_RS10190	COG4166	transmembrane transport
DXE54_RS10195	COG0583	DNA-binding transcription factor activity
DXE54_RS10200	COG1073	alpha beta
DXE54_RS10210	COG0702	epimerase
DXE54_RS10215	COG2866	Carboxypeptidase
DXE54_RS10220	COG4948	Mandelate Racemase Muconate Lactonizing
DXE54_RS10225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DXE54_RS10230	COG3283	Transcriptional regulator of aromatic amino acids metabolism
DXE54_RS10240	COG3106	COG3106 Predicted ATPase
DXE54_RS10245	COG1609	Transcriptional regulator
DXE54_RS10255	COG3842	ATPase activity
DXE54_RS10260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXE54_RS10265	COG1554	hydrolase, family 65, central catalytic
DXE54_RS10270	COG0673	inositol 2-dehydrogenase activity
DXE54_RS10275	COG1082	Xylose isomerase domain protein TIM barrel
DXE54_RS10280	COG1063	alcohol dehydrogenase
DXE54_RS10285	COG0395	ABC-type sugar transport system, permease component
DXE54_RS10290	COG1175	transmembrane transport
DXE54_RS10295	COG1653	transport
DXE54_RS10300	COG0366	Alpha amylase catalytic
DXE54_RS10305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DXE54_RS10315	COG1983	PspC domain protein
DXE54_RS10325	COG1842	Phage shock protein A
DXE54_RS10330	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DXE54_RS10335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DXE54_RS10340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DXE54_RS10345	COG1012	belongs to the aldehyde dehydrogenase family
DXE54_RS10350	COG1396	sequence-specific DNA binding
DXE54_RS10350	COG1917	Cupin 2, conserved barrel domain protein
DXE54_RS10355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DXE54_RS10360	COG0174	glutamine synthetase
DXE54_RS10370	COG0531	amino acid
DXE54_RS10380	COG4166	transmembrane transport
DXE54_RS10385	COG4168	peptide transport system, permease
DXE54_RS10390	COG4171	peptide transport system, permease
DXE54_RS10395	COG4172	Belongs to the ABC transporter superfamily
DXE54_RS10400	COG4172	Belongs to the ABC transporter superfamily
DXE54_RS10405	COG2814	Major facilitator Superfamily
DXE54_RS10415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DXE54_RS10420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXE54_RS10430	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DXE54_RS10435	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DXE54_RS10435	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DXE54_RS10450	COG5001	Diguanylate cyclase
DXE54_RS10460	COG1349	DNA-binding transcription factor activity
DXE54_RS10470	COG0023	Translation Initiation Factor
DXE54_RS10480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DXE54_RS10485	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
DXE54_RS10490	COG0671	phosphoesterase, PA-phosphatase related
DXE54_RS10500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DXE54_RS10520	COG0583	DNA-binding transcription factor activity
DXE54_RS10525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DXE54_RS10535	COG0616	signal peptide processing
DXE54_RS10540	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS10545	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DXE54_RS10550	COG1187	pseudouridine synthase activity
DXE54_RS10555	COG4907	membrane protein (DUF2207)
DXE54_RS10560	COG0009	L-threonylcarbamoyladenylate synthase
DXE54_RS10565	COG0613	PHP domain protein
DXE54_RS10575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DXE54_RS10580	COG0512	Glutamine amidotransferase of anthranilate synthase
DXE54_RS10580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DXE54_RS10585	COG0135	phosphoribosylanthranilate isomerase activity
DXE54_RS10585	COG0134	indole-3-glycerol-phosphate synthase activity
DXE54_RS10595	COG0159	tryptophan synthase activity
DXE54_RS10600	COG3729	General stress protein
DXE54_RS10605	COG3685	Protein conserved in bacteria
DXE54_RS10610	COG3685	Protein conserved in bacteria
DXE54_RS10755	COG3547	Transposase (IS116 IS110 IS902 family)
DXE54_RS10775	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DXE54_RS10780	COG1403	HNH endonuclease
DXE54_RS10810	COG1846	Transcriptional regulator
DXE54_RS10835	COG1396	sequence-specific DNA binding
DXE54_RS10880	COG0582	viral genome integration into host DNA
DXE54_RS10885	COG3047	cAMP biosynthetic process
DXE54_RS10905	COG1607	acyl-coa hydrolase
DXE54_RS10910	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DXE54_RS10915	COG2350	Protein conserved in bacteria
DXE54_RS10920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DXE54_RS10940	COG4608	Belongs to the ABC transporter superfamily
DXE54_RS10945	COG0444	Belongs to the ABC transporter superfamily
DXE54_RS10950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXE54_RS10955	COG0601	transmembrane transport
DXE54_RS10960	COG4166	transmembrane transport
DXE54_RS10965	COG2095	MarC family integral membrane protein
DXE54_RS10970	COG1454	alcohol dehydrogenase
DXE54_RS10970	COG1012	belongs to the aldehyde dehydrogenase family
DXE54_RS10975	COG1435	thymidine kinase activity
DXE54_RS10985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DXE54_RS10990	COG0745	RESPONSE REGULATOR receiver
DXE54_RS10995	COG1752	Esterase of the alpha-beta hydrolase superfamily
DXE54_RS11005	COG0788	formyltetrahydrofolate deformylase activity
DXE54_RS11025	COG2181	nitrate reductase activity
DXE54_RS11030	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DXE54_RS11035	COG1140	nitrate reductase beta subunit
DXE54_RS11040	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DXE54_RS11045	COG2223	nitrite transmembrane transporter activity
DXE54_RS11050	COG3850	Histidine kinase
DXE54_RS11055	COG2197	response regulator
DXE54_RS11060	COG4932	domain protein
DXE54_RS11065	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DXE54_RS11070	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DXE54_RS11075	COG4572	Cation transport regulator
DXE54_RS11080	COG0387	Pfam Sodium calcium exchanger
DXE54_RS11100	COG2912	Transglutaminase-like superfamily
DXE54_RS11105	COG3094	Invasion gene expression up-regulator, SirB
DXE54_RS11110	COG2890	protein-(glutamine-N5) methyltransferase activity
DXE54_RS11135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DXE54_RS11140	COG0659	secondary active sulfate transmembrane transporter activity
DXE54_RS11155	COG0012	GTP binding
DXE54_RS11175	COG3284	Transcriptional regulator
DXE54_RS11180	COG2376	Dihydroxyacetone kinase
DXE54_RS11185	COG1461	Dihydroxyacetone kinase
DXE54_RS11190	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DXE54_RS11190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DXE54_RS11190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS11200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DXE54_RS11205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXE54_RS11210	COG1120	ATPase activity
DXE54_RS11215	COG0500	methyltransferase
DXE54_RS11220	COG0157	Belongs to the NadC ModD family
DXE54_RS11235	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DXE54_RS11245	COG1619	proteins homologs of microcin C7 resistance protein MccF
DXE54_RS11270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DXE54_RS11280	COG2719	SpoVR family
DXE54_RS11295	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DXE54_RS11300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DXE54_RS11305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DXE54_RS11320	COG0179	Fumarylacetoacetate (FAA) hydrolase
DXE54_RS11345	COG2894	cell division
DXE54_RS11400	COG2200	EAL domain
DXE54_RS11425	COG2200	EAL domain
DXE54_RS11430	COG0789	Transcriptional regulator
DXE54_RS11435	COG5562	phage envelope protein
DXE54_RS11455	COG0538	isocitrate dehydrogenase activity
DXE54_RS11460	COG1187	pseudouridine synthase activity
DXE54_RS11480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DXE54_RS11490	COG2205	protein histidine kinase activity
DXE54_RS11500	COG4220	transposase activity
DXE54_RS11590	COG2850	peptidyl-arginine hydroxylation
DXE54_RS11600	COG3842	ATPase activity
DXE54_RS11640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXE54_RS11650	COG0582	viral genome integration into host DNA
DXE54_RS11655	COG1177	transmembrane transport
DXE54_RS11660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DXE54_RS11665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DXE54_RS11675	COG4591	ABC-type transport system involved in lipoprotein release permease component
DXE54_RS11680	COG1136	(ABC) transporter
DXE54_RS11685	COG4591	ABC-type transport system involved in lipoprotein release permease component
DXE54_RS11690	COG4763	Acyl-transferase
DXE54_RS11695	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DXE54_RS11700	COG1376	ErfK ybiS ycfS ynhG family protein
DXE54_RS11700	COG1388	LysM domain
DXE54_RS11710	COG1309	transcriptional regulator
DXE54_RS11715	COG3134	Outer membrane lipoprotein
DXE54_RS11720	COG1252	NADH dehydrogenase
DXE54_RS11740	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
DXE54_RS11745	COG5633	Lipoprotein
DXE54_RS11750	COG0537	adenosine 5'-monophosphoramidase activity
DXE54_RS11755	COG4773	Receptor
DXE54_RS11760	COG1263	PTS System
DXE54_RS11760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXE54_RS11765	COG0084	hydrolase, TatD family'
DXE54_RS11770	COG0470	DNA polymerase III
DXE54_RS11780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DXE54_RS11785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DXE54_RS11790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXE54_RS11800	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS11805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DXE54_RS11825	COG1399	metal-binding, possibly nucleic acid-binding protein
DXE54_RS11830	COG0424	maF-like protein
DXE54_RS11835	COG0564	pseudouridine synthase activity
DXE54_RS11840	COG1530	ribonuclease E activity
DXE54_RS11845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DXE54_RS11850	COG1256	bacterial-type flagellum assembly
DXE54_RS11855	COG3951	Flagellar rod assembly protein muramidase FlgJ
DXE54_RS11855	COG1705	Flagellar rod assembly protein muramidase FlgJ
DXE54_RS11870	COG4786	Flagellar basal body rod
DXE54_RS11875	COG4787	bacterial-type flagellum-dependent cell motility
DXE54_RS11880	COG1749	Flagellar hook protein flgE
DXE54_RS11885	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DXE54_RS11890	COG1558	bacterial-type flagellum-dependent cell motility
DXE54_RS11895	COG1815	bacterial-type flagellum-dependent cell motility
DXE54_RS11900	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
DXE54_RS11905	COG2747	anti-sigma28 factor FlgM
DXE54_RS11910	COG3418	PFAM FlgN family protein
DXE54_RS11915	COG0728	peptidoglycan biosynthetic process
DXE54_RS11920	COG0673	inositol 2-dehydrogenase activity
DXE54_RS11930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXE54_RS11940	COG2999	glutathione oxidoreductase activity
DXE54_RS11975	COG3038	cytochrome b561
DXE54_RS11980	COG2353	YceI-like domain
DXE54_RS11990	COG1560	Kdo2-lipid A biosynthetic process
DXE54_RS12005	COG5645	(Lipo)protein
DXE54_RS12010	COG2943	transferase activity, transferring hexosyl groups
DXE54_RS12025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DXE54_RS12030	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DXE54_RS12055	COG2197	response regulator
DXE54_RS12070	COG1462	curli production assembly transport component CsgG
DXE54_RS12080	COG3381	protein complex oligomerization
DXE54_RS12130	COG2003	Belongs to the UPF0758 family
DXE54_RS12160	COG3468	outer membrane autotransporter barrel domain protein
DXE54_RS12240	COG1475	DNA binding
DXE54_RS12245	COG3969	phosphoadenosine phosphosulfate
DXE54_RS12250	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DXE54_RS12255	COG2831	hemolysin activation secretion protein
DXE54_RS12335	COG4771	TonB-dependent receptor
DXE54_RS12395	COG1358	cellular component organization or biogenesis
DXE54_RS12430	COG4372	Transposase
DXE54_RS12435	COG3436	PFAM IS66 Orf2 family protein
DXE54_RS12460	COG0254	rRNA binding
DXE54_RS12505	COG0829	nickel cation binding
DXE54_RS12515	COG2194	sulfuric ester hydrolase activity
DXE54_RS12520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DXE54_RS12545	COG3121	Chaperone
DXE54_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS12555	COG3710	Transcriptional regulator
DXE54_RS12565	COG2200	EAL domain
DXE54_RS12570	COG0457	Tetratricopeptide repeat
DXE54_RS12580	COG1215	transferase activity, transferring glycosyl groups
DXE54_RS12585	COG3658	cytochrome
DXE54_RS12590	COG1702	phosphate starvation-inducible protein PhoH
DXE54_RS12600	COG2822	iron ion transport
DXE54_RS12615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DXE54_RS12625	COG0506	proline dehydrogenase activity
DXE54_RS12625	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DXE54_RS12625	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DXE54_RS12630	COG1309	transcriptional regulator
DXE54_RS12665	COG2233	PERMEase
DXE54_RS12670	COG3729	General stress protein
DXE54_RS12710	COG0243	molybdopterin cofactor binding
DXE54_RS12715	COG3005	denitrification pathway
DXE54_RS12720	COG0745	RESPONSE REGULATOR receiver
DXE54_RS12725	COG1879	ABC-type sugar transport system periplasmic component
DXE54_RS12730	COG2205	protein histidine kinase activity
DXE54_RS12730	COG0784	Response regulator, receiver
DXE54_RS12730	COG2198	Histidine kinase
DXE54_RS12735	COG0348	domain, Protein
DXE54_RS12755	COG1278	Cold shock
DXE54_RS12760	COG1278	Cold shock
DXE54_RS12780	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DXE54_RS12785	COG1596	polysaccharide export
DXE54_RS12790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DXE54_RS12795	COG0489	protein tyrosine kinase activity
DXE54_RS12795	COG3206	protein involved in exopolysaccharide biosynthesis
DXE54_RS12810	COG1294	oxidase, subunit
DXE54_RS12815	COG1271	oxidase subunit
DXE54_RS12820	COG1773	rubredoxin
DXE54_RS12825	COG1999	signal sequence binding
DXE54_RS12830	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DXE54_RS12835	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
DXE54_RS12840	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DXE54_RS12845	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DXE54_RS12870	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS12885	COG2032	superoxide dismutase activity
DXE54_RS12980	COG4220	transposase activity
DXE54_RS13010	COG3772	lysozyme
DXE54_RS13055	COG2207	Transcriptional regulator
DXE54_RS13070	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DXE54_RS13075	COG1403	HNH endonuclease
DXE54_RS13085	COG3111	PFAM Bacterial OB fold (BOF) protein
DXE54_RS13120	COG1846	Transcriptional regulator
DXE54_RS13165	COG0582	viral genome integration into host DNA
DXE54_RS13180	COG3093	addiction module antidote protein HigA
DXE54_RS13185	COG3423	Transcriptional regulator
DXE54_RS13230	COG2373	Large extracellular alpha-helical protein
DXE54_RS13230	COG1388	LysM domain
DXE54_RS13230	COG4932	domain protein
DXE54_RS13250	COG0477	Major facilitator Superfamily
DXE54_RS13255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DXE54_RS13260	COG0217	transcriptional regulatory protein
DXE54_RS13270	COG0534	Mate efflux family protein
DXE54_RS13280	COG0583	DNA-binding transcription factor activity
DXE54_RS13285	COG0583	DNA-binding transcription factor activity
DXE54_RS13295	COG1376	ErfK ybiS ycfS ynhG family protein
DXE54_RS13310	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
DXE54_RS13320	COG3436	PFAM IS66 Orf2 family protein
DXE54_RS13400	COG2003	Belongs to the UPF0758 family
DXE54_RS13445	COG1289	transmembrane transporter activity
DXE54_RS13455	COG1686	Belongs to the peptidase S11 family
DXE54_RS13460	COG2925	Exonuclease
DXE54_RS13465	COG0425	Belongs to the sulfur carrier protein TusA family
DXE54_RS13470	COG2391	methyltransferase activity
DXE54_RS13475	COG0531	amino acid
DXE54_RS13485	COG0583	DNA-binding transcription factor activity
DXE54_RS13490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXE54_RS13495	COG4115	mRNA cleavage
DXE54_RS13500	COG2161	toxin-antitoxin pair type II binding
DXE54_RS13515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DXE54_RS13525	COG0131	Imidazoleglycerol-phosphate dehydratase
DXE54_RS13525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DXE54_RS13530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DXE54_RS13555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DXE54_RS13560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DXE54_RS13630	COG2089	acid synthase
DXE54_RS13640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DXE54_RS13650	COG0438	transferase activity, transferring glycosyl groups
DXE54_RS13655	COG2327	Polysaccharide pyruvyl transferase
DXE54_RS13660	COG2244	polysaccharide biosynthetic process
DXE54_RS13665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DXE54_RS13670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DXE54_RS13675	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DXE54_RS13675	COG0662	Cupin 2, conserved barrel domain protein
DXE54_RS13680	COG0297	glycogen (starch) synthase activity
DXE54_RS13685	COG1051	belongs to the nudix hydrolase family
DXE54_RS13690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXE54_RS13695	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DXE54_RS13700	COG0110	maltose O-acetyltransferase activity
DXE54_RS13705	COG1216	Glycosyl transferase, family 2
DXE54_RS13715	COG0438	transferase activity, transferring glycosyl groups
DXE54_RS13720	COG1045	serine acetyltransferase
DXE54_RS13725	COG0463	Glycosyl transferase, family 2
DXE54_RS13730	COG3206	protein involved in exopolysaccharide biosynthesis
DXE54_RS13730	COG0489	protein tyrosine kinase activity
DXE54_RS13735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DXE54_RS13740	COG1596	polysaccharide export
DXE54_RS13750	COG1253	flavin adenine dinucleotide binding
DXE54_RS13755	COG2982	Protein involved in outer membrane biogenesis
DXE54_RS13765	COG0572	uridine kinase
DXE54_RS13770	COG3447	MASE1 domain protein
DXE54_RS13770	COG5001	Diguanylate cyclase
DXE54_RS13770	COG5002	protein histidine kinase activity
DXE54_RS13775	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DXE54_RS13780	COG0443	Heat shock 70 kDa protein
DXE54_RS13785	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
DXE54_RS13790	COG0631	protein serine/threonine phosphatase activity
DXE54_RS13795	COG4245	von Willebrand factor, type A
DXE54_RS13840	COG2205	protein histidine kinase activity
DXE54_RS13845	COG0745	RESPONSE REGULATOR receiver
DXE54_RS13855	COG0826	peptidase U32
DXE54_RS13880	COG3775	system Galactitol-specific IIC component
DXE54_RS13885	COG3414	Phosphotransferase system galactitol-specific IIB component
DXE54_RS13890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS13905	COG1830	Aldolase
DXE54_RS13910	COG2211	Major facilitator Superfamily
DXE54_RS13915	COG1397	ADP-ribosylglycohydrolase
DXE54_RS13920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXE54_RS13925	COG2188	Transcriptional regulator
DXE54_RS13930	COG3757	hydrolase, family 25
DXE54_RS13935	COG0351	phosphomethylpyrimidine kinase
DXE54_RS13955	COG5455	response to cobalt ion
DXE54_RS13960	COG3539	Fimbrial protein
DXE54_RS13965	COG3188	usher protein
DXE54_RS13970	COG3121	Chaperone
DXE54_RS13975	COG3539	Fimbrial protein
DXE54_RS13985	COG0489	protein tyrosine kinase activity
DXE54_RS14005	COG3831	ATPase activity
DXE54_RS14015	COG0714	Associated with various cellular activities
DXE54_RS14020	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DXE54_RS14025	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DXE54_RS14030	COG4715	Zinc finger, swim domain protein
DXE54_RS14035	COG4808	Protein conserved in bacteria
DXE54_RS14040	COG4807	Protein conserved in bacteria
DXE54_RS14045	COG3279	Response regulator of the LytR AlgR family
DXE54_RS14050	COG3275	phosphorelay sensor kinase activity
DXE54_RS14100	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS14235	COG3772	lysozyme
DXE54_RS14285	COG1174	glycine betaine transport
DXE54_RS14290	COG1125	glycine betaine transport
DXE54_RS14295	COG1174	glycine betaine transport
DXE54_RS14300	COG1732	Glycine betaine
DXE54_RS14305	COG1472	Belongs to the glycosyl hydrolase 3 family
DXE54_RS14310	COG0277	FAD linked oxidase domain protein
DXE54_RS14315	COG1686	Belongs to the peptidase S11 family
DXE54_RS14325	COG0586	Pfam SNARE associated Golgi protein
DXE54_RS14330	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS14345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DXE54_RS14355	COG1346	cytolysis
DXE54_RS14365	COG2949	membrane
DXE54_RS14375	COG0493	'glutamate synthase
DXE54_RS14380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DXE54_RS14380	COG0167	dihydroorotate dehydrogenase activity
DXE54_RS14385	COG4211	Belongs to the binding-protein-dependent transport system permease family
DXE54_RS14390	COG1129	ABC transporter
DXE54_RS14395	COG1879	ABC-type sugar transport system periplasmic component
DXE54_RS14400	COG1609	Transcriptional regulator
DXE54_RS14405	COG2311	Membrane
DXE54_RS14415	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DXE54_RS14420	COG4771	TonB-dependent receptor
DXE54_RS14425	COG0833	amino acid
DXE54_RS14430	COG0583	DNA-binding transcription factor activity
DXE54_RS14435	COG2855	membrane
DXE54_RS14445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXE54_RS14445	COG1522	sequence-specific DNA binding
DXE54_RS14450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DXE54_RS14460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXE54_RS14465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DXE54_RS14470	COG2313	pseudouridylate synthase activity
DXE54_RS14475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXE54_RS14480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXE54_RS14480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXE54_RS14480	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DXE54_RS14485	COG1105	Belongs to the carbohydrate kinase PfkB family
DXE54_RS14490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS14490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS14495	COG2814	Major facilitator Superfamily
DXE54_RS14510	COG0246	Mannitol dehydrogenase
DXE54_RS14515	COG0523	cobalamin synthesis protein
DXE54_RS14520	COG0671	phosphoesterase, PA-phosphatase related
DXE54_RS14525	COG0791	NLP P60 protein
DXE54_RS14530	COG2200	EAL domain
DXE54_RS14535	COG4166	transmembrane transport
DXE54_RS14540	COG4174	ABC transporter (Permease)
DXE54_RS14545	COG4239	(ABC) transporter, permease
DXE54_RS14550	COG4172	Belongs to the ABC transporter superfamily
DXE54_RS14560	COG2814	Major facilitator Superfamily
DXE54_RS14565	COG1187	pseudouridine synthase activity
DXE54_RS14570	COG1061	Type III restriction enzyme res subunit
DXE54_RS14590	COG3083	sulfuric ester hydrolase activity
DXE54_RS14600	COG3468	outer membrane autotransporter barrel domain protein
DXE54_RS14605	COG2197	response regulator
DXE54_RS14610	COG4235	cytochrome complex assembly
DXE54_RS14610	COG3088	subunit of a heme lyase
DXE54_RS14615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXE54_RS14620	COG1138	Cytochrome C-type biogenesis protein
DXE54_RS14630	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DXE54_RS14635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DXE54_RS14640	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DXE54_RS14645	COG4133	protoheme IX ABC transporter activity
DXE54_RS14650	COG3005	denitrification pathway
DXE54_RS14655	COG3043	anaerobic respiration
DXE54_RS14660	COG0348	domain, Protein
DXE54_RS14665	COG0437	4 iron, 4 sulfur cluster binding
DXE54_RS14675	COG3062	negative regulation of establishment of protein localization
DXE54_RS14680	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS14680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS14695	COG4615	Cyclic peptide transporter
DXE54_RS14700	COG3145	DNA-N1-methyladenine dioxygenase activity
DXE54_RS14705	COG2169	Transcriptional regulator
DXE54_RS14705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DXE54_RS14710	COG1477	protein flavinylation
DXE54_RS14715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DXE54_RS14720	COG0642	Histidine kinase
DXE54_RS14720	COG2198	Histidine kinase
DXE54_RS14725	COG2197	response regulator
DXE54_RS14730	COG0784	Response regulator, receiver
DXE54_RS14730	COG2205	protein histidine kinase activity
DXE54_RS14735	COG4676	Protein conserved in bacteria
DXE54_RS14740	COG5445	Predicted secreted protein (DUF2300)
DXE54_RS14745	COG5445	Predicted secreted protein (DUF2300)
DXE54_RS14755	COG3234	Protein of unknown function (DUF1175)
DXE54_RS14760	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
DXE54_RS14765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DXE54_RS14775	COG3468	outer membrane autotransporter barrel domain protein
DXE54_RS14780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXE54_RS14785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXE54_RS14790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DXE54_RS14795	COG3642	lipopolysaccharide core region biosynthetic process
DXE54_RS14800	COG2814	Major facilitator Superfamily
DXE54_RS14805	COG0583	DNA-binding transcription factor activity
DXE54_RS14810	COG0584	glycerophosphoryl diester phosphodiesterase
DXE54_RS14815	COG2271	Major facilitator Superfamily
DXE54_RS14820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DXE54_RS14830	COG0247	lactate metabolic process
DXE54_RS14835	COG5464	transposase or invertase
DXE54_RS14845	COG3836	Belongs to the HpcH HpaI aldolase family
DXE54_RS14850	COG2271	Major facilitator Superfamily
DXE54_RS14860	COG1414	Transcriptional regulator
DXE54_RS14925	COG0318	PFAM AMP-dependent synthetase and ligase
DXE54_RS14935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DXE54_RS14950	COG1169	isochorismate synthase
DXE54_RS14955	COG4575	ribosome binding
DXE54_RS14960	COG2153	protein acetylation
DXE54_RS14970	COG5160	protein modification by small protein removal
DXE54_RS14990	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXE54_RS14995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DXE54_RS15005	COG0839	Belongs to the complex I subunit 6 family
DXE54_RS15020	COG1034	ATP synthesis coupled electron transport
DXE54_RS15025	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DXE54_RS15030	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DXE54_RS15050	COG0583	DNA-binding transcription factor activity
DXE54_RS15055	COG0436	Aminotransferase
DXE54_RS15065	COG0471	metal ion transport
DXE54_RS15065	COG0490	domain, Protein
DXE54_RS15070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXE54_RS15085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DXE54_RS15090	COG0857	belongs to the CobB CobQ family
DXE54_RS15090	COG0280	phosphate acetyltransferase
DXE54_RS15095	COG1288	antiporter activity
DXE54_RS15100	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DXE54_RS15105	COG0622	Phosphoesterase
DXE54_RS15110	COG0625	glutathione transferase activity
DXE54_RS15115	COG0625	glutathione transferase activity
DXE54_RS15120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DXE54_RS15125	COG1090	epimerase
DXE54_RS15130	COG5464	transposase or invertase
DXE54_RS15135	COG4598	ABC transporter
DXE54_RS15140	COG4160	amino acid transport
DXE54_RS15145	COG4215	(ABC) transporter
DXE54_RS15150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXE54_RS15155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXE54_RS15160	COG0163	prenyltransferase activity
DXE54_RS15165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DXE54_RS15170	COG1286	toxin biosynthetic process
DXE54_RS15175	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
DXE54_RS15180	COG0285	dihydrofolate synthase activity
DXE54_RS15190	COG0586	Pfam SNARE associated Golgi protein
DXE54_RS15200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DXE54_RS15215	COG2814	Major facilitator Superfamily
DXE54_RS15220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXE54_RS15235	COG3101	peptidyl-lysine hydroxylation
DXE54_RS15240	COG0730	response to heat
DXE54_RS15255	COG2890	protein-(glutamine-N5) methyltransferase activity
DXE54_RS15270	COG3539	Fimbrial protein
DXE54_RS15275	COG3539	Fimbrial protein
DXE54_RS15280	COG3539	Fimbrial protein
DXE54_RS15285	COG3121	Chaperone
DXE54_RS15290	COG3188	usher protein
DXE54_RS15295	COG3539	Fimbrial protein
DXE54_RS15300	COG2062	phosphohistidine phosphatase, SixA
DXE54_RS15315	COG3691	Protein conserved in bacteria
DXE54_RS15320	COG2067	long-chain fatty acid transport protein
DXE54_RS15330	COG2853	Lipoprotein
DXE54_RS15335	COG2116	formate transmembrane transporter activity
DXE54_RS15345	COG0583	DNA-binding transcription factor activity
DXE54_RS15350	COG2610	gluconate transmembrane transporter activity
DXE54_RS15360	COG0477	Major facilitator Superfamily
DXE54_RS15365	COG1566	PFAM secretion protein HlyD family protein
DXE54_RS15370	COG2197	response regulator
DXE54_RS15375	COG0784	Response regulator, receiver
DXE54_RS15375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXE54_RS15375	COG2205	protein histidine kinase activity
DXE54_RS15375	COG2198	Histidine kinase
DXE54_RS15380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DXE54_RS15385	COG0679	Auxin Efflux Carrier
DXE54_RS15390	COG0028	Belongs to the TPP enzyme family
DXE54_RS15415	COG1560	Kdo2-lipid A biosynthetic process
DXE54_RS15425	COG0436	Aminotransferase
DXE54_RS15430	COG3275	phosphorelay sensor kinase activity
DXE54_RS15435	COG3279	Response regulator of the LytR AlgR family
DXE54_RS15440	COG2207	Transcriptional regulator
DXE54_RS15445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS15445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS15445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DXE54_RS15450	COG1363	Peptidase, m42
DXE54_RS15455	COG0006	proline dipeptidase activity
DXE54_RS15460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXE54_RS15465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXE54_RS15490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DXE54_RS15495	COG2199	diguanylate cyclase activity
DXE54_RS15495	COG2200	EAL domain
DXE54_RS15510	COG3415	Transposase
DXE54_RS15515	COG3415	Transposase
DXE54_RS15520	COG0675	Transposase, IS605 OrfB family
DXE54_RS15565	COG0583	DNA-binding transcription factor activity
DXE54_RS15570	COG0385	Bile acid
DXE54_RS15575	COG3530	Putative quorum-sensing-regulated virulence factor
DXE54_RS15595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DXE54_RS15600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS15605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DXE54_RS15610	COG2190	(PTS) system
DXE54_RS15625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DXE54_RS15630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DXE54_RS15635	COG4208	sulfate ABC transporter
DXE54_RS15640	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DXE54_RS15645	COG4150	thiosulfate binding
DXE54_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS15665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXE54_RS15665	COG1263	PTS System
DXE54_RS15670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DXE54_RS15675	COG2837	iron assimilation
DXE54_RS15695	COG0860	N-Acetylmuramoyl-L-alanine amidase
DXE54_RS15705	COG2207	Transcriptional regulator
DXE54_RS15710	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DXE54_RS15715	COG4816	utilization protein
DXE54_RS15730	COG4819	ethanolamine utilization protein
DXE54_RS15735	COG3192	ethanolamine utilization protein
DXE54_RS15740	COG1454	alcohol dehydrogenase
DXE54_RS15745	COG4820	ethanolamine utilization protein (EutJ)
DXE54_RS15750	COG1012	belongs to the aldehyde dehydrogenase family
DXE54_RS15755	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
DXE54_RS15760	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DXE54_RS15765	COG0280	phosphate acetyltransferase
DXE54_RS15770	COG4812	Cobalamin adenosyltransferase
DXE54_RS15775	COG4766	ethanolamine catabolic process
DXE54_RS15780	COG4917	ethanolamine utilization protein
DXE54_RS15785	COG4810	utilization protein
DXE54_RS15790	COG0281	malic enzyme
DXE54_RS15790	COG0280	phosphate acetyltransferase
DXE54_RS15795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DXE54_RS15800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DXE54_RS15805	COG5342	invasion associated locus B
DXE54_RS15815	COG0493	'glutamate synthase
DXE54_RS15815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS15825	COG3850	Histidine kinase
DXE54_RS15830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DXE54_RS15840	COG1393	Belongs to the ArsC family
DXE54_RS15855	COG0400	carboxylic ester hydrolase activity
DXE54_RS15865	COG2321	neutral zinc metallopeptidase
DXE54_RS15875	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DXE54_RS15885	COG2716	regulation of RNA biosynthetic process
DXE54_RS15890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DXE54_RS15895	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS15900	COG0651	ATP synthesis coupled electron transport
DXE54_RS15905	COG0650	Formate hydrogenlyase subunit 4
DXE54_RS15910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DXE54_RS15915	COG4237	Hydrogenase 4 membrane
DXE54_RS15925	COG3261	NADH dehydrogenase
DXE54_RS15925	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DXE54_RS15930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXE54_RS15935	COG3260	NADH ubiquinone oxidoreductase 20
DXE54_RS15945	COG3604	Transcriptional regulator
DXE54_RS15955	COG3547	Transposase (IS116 IS110 IS902 family)
DXE54_RS15965	COG0628	permease
DXE54_RS15970	COG4783	chaperone-mediated protein folding
DXE54_RS15975	COG1393	Belongs to the ArsC family
DXE54_RS15985	COG2233	PERMEase
DXE54_RS16000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DXE54_RS16005	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DXE54_RS16010	COG0248	Ppx GppA phosphatase
DXE54_RS16015	COG2200	EAL domain
DXE54_RS16030	COG3133	Outer membrane lipoprotein
DXE54_RS16045	COG0517	IMP dehydrogenase activity
DXE54_RS16045	COG0516	GMP reductase activity
DXE54_RS16070	COG1645	bacterial-type flagellum-dependent swarming motility
DXE54_RS16085	COG2976	Protein conserved in bacteria
DXE54_RS16115	COG4953	penicillin-binding protein 1C
DXE54_RS16120	COG2373	Large extracellular alpha-helical protein
DXE54_RS16125	COG2897	thiosulfate sulfurtransferase activity
DXE54_RS16140	COG2975	iron-sulfur cluster assembly
DXE54_RS16145	COG0633	Ferredoxin
DXE54_RS16165	COG0822	iron-sulfur transferase activity
DXE54_RS16185	COG0483	inositol monophosphate 1-phosphatase activity
DXE54_RS16190	COG1073	alpha beta
DXE54_RS16195	COG3711	transcriptional antiterminator
DXE54_RS16200	COG2814	Major facilitator Superfamily
DXE54_RS16205	COG0583	DNA-binding transcription factor activity
DXE54_RS16210	COG4638	Rieske (2fe-2S)
DXE54_RS16235	COG1879	ABC-type sugar transport system periplasmic component
DXE54_RS16240	COG0457	Tetratricopeptide repeat
DXE54_RS16245	COG1940	carbohydrate kinase activity
DXE54_RS16255	COG1017	nitric oxide dioxygenase activity
DXE54_RS16255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DXE54_RS16260	COG0347	Belongs to the P(II) protein family
DXE54_RS16265	COG2204	response regulator
DXE54_RS16270	COG3170	Tfp pilus assembly protein FimV
DXE54_RS16275	COG2205	protein histidine kinase activity
DXE54_RS16280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DXE54_RS16280	COG0047	phosphoribosylformylglycinamidine synthase activity
DXE54_RS16290	COG0590	tRNA wobble adenosine to inosine editing
DXE54_RS16295	COG0560	Phosphoserine phosphatase
DXE54_RS16300	COG1737	Transcriptional regulator
DXE54_RS16305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS16320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DXE54_RS16340	COG0681	Belongs to the peptidase S26 family
DXE54_RS16350	COG3086	response to oxidative stress
DXE54_RS16355	COG3026	antisigma factor binding
DXE54_RS16360	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
DXE54_RS16365	COG1595	DNA-templated transcription, initiation
DXE54_RS16375	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DXE54_RS16385	COG0513	Belongs to the DEAD box helicase family
DXE54_RS16390	COG0583	DNA-binding transcription factor activity
DXE54_RS16410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DXE54_RS16415	COG3118	belongs to the thioredoxin family
DXE54_RS16420	COG3148	PFAM DTW domain containing protein
DXE54_RS16425	COG1042	CoA-binding domain protein
DXE54_RS16425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXE54_RS16425	COG0045	succinate-CoA ligase (ADP-forming) activity
DXE54_RS16430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DXE54_RS16435	COG5544	Lipoprotein
DXE54_RS16465	COG0542	response to heat
DXE54_RS16475	COG0564	pseudouridine synthase activity
DXE54_RS16480	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DXE54_RS16485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DXE54_RS16495	COG0077	Prephenate dehydratase
DXE54_RS16495	COG1605	Chorismate mutase
DXE54_RS16500	COG1605	Chorismate mutase
DXE54_RS16500	COG0287	Prephenate dehydrogenase
DXE54_RS16505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DXE54_RS16520	COG2199	diguanylate cyclase activity
DXE54_RS16525	COG2885	chlorophyll binding
DXE54_RS16550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DXE54_RS16555	COG4137	Cytochrome C assembly protein
DXE54_RS16560	COG4536	flavin adenine dinucleotide binding
DXE54_RS16575	COG0497	DNA recombination
DXE54_RS16580	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DXE54_RS16590	COG2867	negative regulation of translational initiation
DXE54_RS16630	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS16705	COG0579	oxidoreductase
DXE54_RS16715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DXE54_RS16720	COG1113	amino acid transport
DXE54_RS16725	COG1802	Transcriptional regulator
DXE54_RS16730	COG1652	LysM domain
DXE54_RS16735	COG0401	homolog of Blt101
DXE54_RS16740	COG0640	Transcriptional regulator
DXE54_RS16745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DXE54_RS16750	COG2916	Histone family protein nucleoid-structuring protein H-NS
DXE54_RS16765	COG4575	ribosome binding
DXE54_RS16775	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DXE54_RS16780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DXE54_RS16790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXE54_RS16795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXE54_RS16800	COG4175	Glycine betaine
DXE54_RS16805	COG4176	ABC-type proline glycine betaine transport system permease component
DXE54_RS16810	COG2113	Glycine betaine
DXE54_RS16815	COG2814	Major facilitator Superfamily
DXE54_RS16820	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DXE54_RS16830	COG1846	Transcriptional regulator
DXE54_RS16835	COG1566	PFAM secretion protein HlyD family protein
DXE54_RS16840	COG2814	Major facilitator Superfamily
DXE54_RS16865	COG1238	metal cluster binding
DXE54_RS16870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXE54_RS16900	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DXE54_RS16920	COG1546	Belongs to the CinA family
DXE54_RS16925	COG2951	lytic endotransglycosylase activity
DXE54_RS16930	COG3730	PTS system glucitol sorbitol-specific
DXE54_RS16935	COG3732	PTS system glucitol sorbitol-specific
DXE54_RS16945	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS16950	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS16955	COG1349	DNA-binding transcription factor activity
DXE54_RS16980	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DXE54_RS16985	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS16990	COG1609	Transcriptional regulator
DXE54_RS16995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXE54_RS16995	COG1263	PTS System
DXE54_RS17000	COG2723	6-phospho-beta-galactosidase activity
DXE54_RS17005	COG5499	transcription regulator containing HTH domain
DXE54_RS17010	COG4680	protein conserved in bacteria
DXE54_RS17020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DXE54_RS17030	COG3260	NADH ubiquinone oxidoreductase 20
DXE54_RS17035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXE54_RS17040	COG3261	NADH dehydrogenase
DXE54_RS17040	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DXE54_RS17045	COG0650	Formate hydrogenlyase subunit 4
DXE54_RS17050	COG0651	ATP synthesis coupled electron transport
DXE54_RS17055	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS17065	COG0375	protein maturation
DXE54_RS17070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DXE54_RS17075	COG0298	carbon dioxide binding
DXE54_RS17080	COG0409	Hydrogenase expression formation protein
DXE54_RS17085	COG0309	Hydrogenase expression formation protein (HypE)
DXE54_RS17090	COG3604	Transcriptional regulator
DXE54_RS17110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DXE54_RS17125	COG0163	prenyltransferase activity
DXE54_RS17135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DXE54_RS17140	COG1388	LysM domain
DXE54_RS17140	COG4942	peptidase
DXE54_RS17195	COG2234	aminopeptidase activity
DXE54_RS17200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXE54_RS17205	COG1518	maintenance of DNA repeat elements
DXE54_RS17230	COG1203	CRISPR-associated helicase, Cas3
DXE54_RS17250	COG0720	synthase
DXE54_RS17255	COG0644	oxidoreductase
DXE54_RS17260	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DXE54_RS17265	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DXE54_RS17270	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DXE54_RS17275	COG2086	electron transfer activity
DXE54_RS17280	COG0477	Major facilitator Superfamily
DXE54_RS17285	COG0277	FAD linked oxidase domain protein
DXE54_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS17295	COG2223	nitrite transmembrane transporter activity
DXE54_RS17300	COG1070	Carbohydrate kinase
DXE54_RS17305	COG0602	queuosine metabolic process
DXE54_RS17315	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DXE54_RS17325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DXE54_RS17340	COG3956	TIGRFAM MazG family protein
DXE54_RS17345	COG2337	Toxic component of a toxin-antitoxin (TA) module
DXE54_RS17350	COG2336	PFAM SpoVT AbrB
DXE54_RS17355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DXE54_RS17365	COG4999	Histidine kinase
DXE54_RS17365	COG3850	Histidine kinase
DXE54_RS17365	COG3437	response regulator, receiver
DXE54_RS17365	COG2205	protein histidine kinase activity
DXE54_RS17370	COG4948	Mandelate Racemase Muconate Lactonizing
DXE54_RS17375	COG4948	Mandelate Racemase Muconate Lactonizing
DXE54_RS17380	COG2271	Major facilitator Superfamily
DXE54_RS17385	COG0716	FMN binding
DXE54_RS17390	COG0564	pseudouridine synthase activity
DXE54_RS17395	COG3098	single-species biofilm formation
DXE54_RS17410	COG1611	Belongs to the LOG family
DXE54_RS17415	COG0814	amino acid
DXE54_RS17420	COG1760	l-serine dehydratase
DXE54_RS17430	COG1454	alcohol dehydrogenase
DXE54_RS17435	COG0235	Class ii aldolase
DXE54_RS17440	COG0738	Major facilitator superfamily
DXE54_RS17450	COG1070	Carbohydrate kinase
DXE54_RS17460	COG1349	DNA-binding transcription factor activity
DXE54_RS17470	COG2363	Small membrane protein
DXE54_RS17475	COG0583	DNA-binding transcription factor activity
DXE54_RS17485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DXE54_RS17490	COG2166	iron-sulfur cluster assembly
DXE54_RS17495	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DXE54_RS17500	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DXE54_RS17520	COG0860	N-Acetylmuramoyl-L-alanine amidase
DXE54_RS17525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DXE54_RS17525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DXE54_RS17530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DXE54_RS17535	COG1074	ATP-dependent DNA helicase activity
DXE54_RS17540	COG1025	Belongs to the peptidase M16 family
DXE54_RS17545	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DXE54_RS17550	COG4967	type IV pilus modification protein PilV
DXE54_RS17560	COG4795	General secretion pathway protein
DXE54_RS17565	COG2165	general secretion pathway protein
DXE54_RS17580	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
DXE54_RS17595	COG0861	Integral membrane protein TerC family
DXE54_RS17605	COG0667	Aldo Keto reductase
DXE54_RS17620	COG1609	Transcriptional regulator
DXE54_RS17630	COG0583	DNA-binding transcription factor activity
DXE54_RS17635	COG1794	racemase activity, acting on amino acids and derivatives
DXE54_RS17640	COG2814	Major facilitator Superfamily
DXE54_RS17645	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS17655	COG0183	Belongs to the thiolase family
DXE54_RS17660	COG0814	amino acid
DXE54_RS17665	COG2771	luxR family
DXE54_RS17695	COG2207	Transcriptional regulator
DXE54_RS17705	COG3387	PFAM Glycoside hydrolase 15-related
DXE54_RS17715	COG4942	peptidase
DXE54_RS17720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DXE54_RS17725	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DXE54_RS17730	COG2080	2 iron, 2 sulfur cluster binding
DXE54_RS17735	COG3829	transcription factor binding
DXE54_RS17740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DXE54_RS17745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DXE54_RS17750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXE54_RS17760	COG0549	Belongs to the carbamate kinase family
DXE54_RS17765	COG3608	succinylglutamate desuccinylase aspartoacylase
DXE54_RS17765	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DXE54_RS17770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DXE54_RS17775	COG2068	MobA-Related Protein
DXE54_RS17780	COG0493	'glutamate synthase
DXE54_RS17780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS17785	COG0402	S-adenosylhomocysteine deaminase activity
DXE54_RS17790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DXE54_RS17795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DXE54_RS17795	COG2080	2 iron, 2 sulfur cluster binding
DXE54_RS17800	COG2233	PERMEase
DXE54_RS17805	COG0402	S-adenosylhomocysteine deaminase activity
DXE54_RS17810	COG2252	PERMEase
DXE54_RS17815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS17820	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS17820	COG0493	'glutamate synthase
DXE54_RS17825	COG2233	PERMEase
DXE54_RS17845	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DXE54_RS17855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DXE54_RS17860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DXE54_RS17865	COG4974	Belongs to the 'phage' integrase family
DXE54_RS17870	COG0716	FMN binding
DXE54_RS17880	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DXE54_RS17890	COG1272	protein, Hemolysin III
DXE54_RS17900	COG2723	6-phospho-beta-galactosidase activity
DXE54_RS17925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DXE54_RS17930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DXE54_RS17935	COG0006	proline dipeptidase activity
DXE54_RS17955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DXE54_RS17970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DXE54_RS18000	COG1024	Enoyl-CoA hydratase
DXE54_RS18005	COG0427	acetyl-CoA hydrolase
DXE54_RS18015	COG2968	Membrane
DXE54_RS18020	COG1279	arginine transmembrane transporter activity
DXE54_RS18085	COG0582	viral genome integration into host DNA
DXE54_RS18105	COG0668	transmembrane transport
DXE54_RS18110	COG0191	fructose-bisphosphate aldolase activity
DXE54_RS18140	COG1122	ATPase activity
DXE54_RS18145	COG1122	ATPase activity
DXE54_RS18150	COG1072	(Pantothenic acid kinase))
DXE54_RS18155	COG3722	fumarate hydratase activity
DXE54_RS18160	COG1494	fructose-1,6-bisphosphatase
DXE54_RS18165	COG1063	alcohol dehydrogenase
DXE54_RS18170	COG2213	PTS system mannitol-specific
DXE54_RS18175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS18180	COG0330	HflC and HflK could
DXE54_RS18185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DXE54_RS18190	COG0501	Belongs to the peptidase M48B family
DXE54_RS18205	COG1166	arginine decarboxylase activity
DXE54_RS18225	COG2814	Major facilitator Superfamily
DXE54_RS18235	COG2356	endonuclease I
DXE54_RS18240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DXE54_RS18245	COG0189	ligase activity
DXE54_RS18260	COG2805	Type II/IV secretion system protein
DXE54_RS18265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DXE54_RS18270	COG0762	integral membrane protein
DXE54_RS18285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DXE54_RS18295	COG0252	asparaginase activity
DXE54_RS18305	COG3171	Protein conserved in bacteria
DXE54_RS18315	COG1194	a g-specific adenine glycosylase
DXE54_RS18330	COG2211	Major facilitator Superfamily
DXE54_RS18335	COG1982	Orn Lys Arg decarboxylase major
DXE54_RS18340	COG1811	Na channel or pump
DXE54_RS18350	COG0582	viral genome integration into host DNA
DXE54_RS18360	COG1595	DNA-templated transcription, initiation
DXE54_RS18365	COG3712	iron ion homeostasis
DXE54_RS18370	COG4772	TonB-dependent receptor
DXE54_RS18375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DXE54_RS18380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXE54_RS18385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXE54_RS18390	COG1120	ATPase activity
DXE54_RS18395	COG2085	NADP oxidoreductase coenzyme F420-dependent
DXE54_RS18435	COG4964	Belongs to the GSP D family
DXE54_RS18460	COG1620	l-lactate permease
DXE54_RS18465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DXE54_RS18470	COG3193	protein, possibly involved in utilization of glycolate and propanediol
DXE54_RS18475	COG0247	lactate metabolic process
DXE54_RS18480	COG0277	FAD linked oxidase domain protein
DXE54_RS18485	COG0277	FAD linked oxidase domain protein
DXE54_RS18490	COG2186	Transcriptional regulator
DXE54_RS18500	COG0318	PFAM AMP-dependent synthetase and ligase
DXE54_RS18510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXE54_RS18515	COG0156	8-amino-7-oxononanoate synthase activity
DXE54_RS18525	COG0795	lipopolysaccharide-transporting ATPase activity
DXE54_RS18530	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
DXE54_RS18540	COG2244	polysaccharide biosynthetic process
DXE54_RS18545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DXE54_RS18550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DXE54_RS18555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DXE54_RS18560	COG0306	phosphate transporter
DXE54_RS18565	COG0754	glutathionylspermidine amidase activity
DXE54_RS18570	COG0625	glutathione transferase activity
DXE54_RS18575	COG0298	carbon dioxide binding
DXE54_RS18585	COG1773	rubredoxin
DXE54_RS18590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DXE54_RS18595	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DXE54_RS18600	COG5557	Pfam Polysulphide reductase, NrfD
DXE54_RS18605	COG0437	4 iron, 4 sulfur cluster binding
DXE54_RS18610	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DXE54_RS18625	COG0667	Aldo Keto reductase
DXE54_RS18635	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS18640	COG0848	biopolymer transport protein
DXE54_RS18645	COG0811	peptide transport
DXE54_RS18650	COG0626	cystathionine gamma-synthase activity
DXE54_RS18655	COG0586	Pfam SNARE associated Golgi protein
DXE54_RS18660	COG2207	Transcriptional regulator
DXE54_RS18665	COG1979	alcohol dehydrogenase
DXE54_RS18670	COG0656	L-ascorbic acid biosynthetic process
DXE54_RS18680	COG4238	major outer membrane lipoprotein
DXE54_RS18685	COG1032	radical SAM domain protein
DXE54_RS18690	COG2132	Multicopper oxidase
DXE54_RS18695	COG0204	Acyl-transferase
DXE54_RS18700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DXE54_RS18705	COG4166	transmembrane transport
DXE54_RS18710	COG2944	sequence-specific DNA binding
DXE54_RS18720	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DXE54_RS18725	COG3111	PFAM Bacterial OB fold (BOF) protein
DXE54_RS18730	COG0745	RESPONSE REGULATOR receiver
DXE54_RS18735	COG0642	Histidine kinase
DXE54_RS18745	COG2249	NAD(P)H dehydrogenase (quinone) activity
DXE54_RS18750	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DXE54_RS18755	COG0187	DNA topoisomerase II activity
DXE54_RS18760	COG3150	esterase
DXE54_RS18765	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DXE54_RS18770	COG3151	Protein conserved in bacteria
DXE54_RS18780	COG1538	Outer membrane efflux protein
DXE54_RS18790	COG0754	glutathionylspermidine amidase activity
DXE54_RS18795	COG3384	dioxygenase
DXE54_RS18830	COG2268	Band 7 protein
DXE54_RS18855	COG3025	triphosphatase activity
DXE54_RS18860	COG4991	sh3 domain protein
DXE54_RS18875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DXE54_RS18885	COG0583	DNA-binding transcription factor activity
DXE54_RS18890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DXE54_RS18895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DXE54_RS18900	COG0471	metal ion transport
DXE54_RS18910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DXE54_RS18915	COG0358	DNA primase activity
DXE54_RS18920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DXE54_RS18935	COG2375	cellular response to nickel ion
DXE54_RS18940	COG1695	Transcriptional regulator
DXE54_RS18945	COG0840	transmembrane signaling receptor activity
DXE54_RS18955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DXE54_RS18960	COG1609	Transcriptional regulator
DXE54_RS18970	COG2731	YhcH YjgK YiaL family protein
DXE54_RS18975	COG0531	amino acid
DXE54_RS18985	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DXE54_RS18985	COG3408	Glycogen debranching enzyme
DXE54_RS18995	COG1902	pentaerythritol trinitrate reductase activity
DXE54_RS18995	COG0446	pyridine nucleotide-disulphide oxidoreductase
DXE54_RS19000	COG5499	transcription regulator containing HTH domain
DXE54_RS19005	COG4680	protein conserved in bacteria
DXE54_RS19015	COG1451	nucleotide metabolic process
DXE54_RS19020	COG2949	membrane
DXE54_RS19025	COG0673	inositol 2-dehydrogenase activity
DXE54_RS19030	COG0861	Integral membrane protein TerC family
DXE54_RS19035	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DXE54_RS19045	COG2721	sulfolactate sulfo-lyase activity
DXE54_RS19055	COG2271	Major facilitator Superfamily
DXE54_RS19060	COG2186	Transcriptional regulator
DXE54_RS19065	COG0586	Pfam SNARE associated Golgi protein
DXE54_RS19075	COG1422	Protein of unknown function (DUF1090)
DXE54_RS19080	COG4575	ribosome binding
DXE54_RS19085	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
DXE54_RS19095	COG2259	Doxx family
DXE54_RS19100	COG0435	Glutathione S-transferase
DXE54_RS19105	COG3152	Membrane
DXE54_RS19110	COG3152	Membrane
DXE54_RS19115	COG0583	DNA-binding transcription factor activity
DXE54_RS19120	COG1741	Belongs to the pirin family
DXE54_RS19135	COG0814	amino acid
DXE54_RS19140	COG1760	l-serine dehydratase
DXE54_RS19145	COG0251	oxidation-reduction process
DXE54_RS19150	COG1882	Formate acetyltransferase
DXE54_RS19155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DXE54_RS19165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DXE54_RS19170	COG0583	DNA-binding transcription factor activity
DXE54_RS19195	COG1929	Belongs to the glycerate kinase type-1 family
DXE54_RS19200	COG2084	Dehydrogenase
DXE54_RS19210	COG2271	Major facilitator Superfamily
DXE54_RS19215	COG2721	sulfolactate sulfo-lyase activity
DXE54_RS19220	COG2002	toxin-antitoxin pair type II binding
DXE54_RS19230	COG1349	DNA-binding transcription factor activity
DXE54_RS19240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXE54_RS19250	COG3716	PTS system mannose fructose sorbose family IID component
DXE54_RS19255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS19260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DXE54_RS19265	COG2222	sugar isomerase
DXE54_RS19275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXE54_RS19275	COG1263	PTS System
DXE54_RS19280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DXE54_RS19300	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DXE54_RS19320	COG2823	Periplasmic or secreted lipoprotein
DXE54_RS19325	COG0701	Predicted permease
DXE54_RS19330	COG0702	epimerase
DXE54_RS19335	COG0693	protein deglycase activity
DXE54_RS19350	COG3153	acetyltransferase
DXE54_RS19355	COG3154	lipid carrier protein
DXE54_RS19360	COG0826	peptidase U32
DXE54_RS19365	COG0826	peptidase U32
DXE54_RS19370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXE54_RS19375	COG0814	amino acid
DXE54_RS19380	COG0513	Belongs to the DEAD box helicase family
DXE54_RS19420	COG0195	Participates in both transcription termination and antitermination
DXE54_RS19450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DXE54_RS19460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DXE54_RS19465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DXE54_RS19475	COG1534	Rna-binding protein
DXE54_RS19480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DXE54_RS19485	COG2027	D-alanyl-D-alanine carboxypeptidase
DXE54_RS19495	COG0697	spore germination
DXE54_RS19510	COG0142	geranyltranstransferase activity
DXE54_RS19515	COG3423	Transcriptional regulator
DXE54_RS19525	COG5007	Belongs to the BolA IbaG family
DXE54_RS19530	COG3113	response to antibiotic
DXE54_RS19535	COG2854	intermembrane phospholipid transfer
DXE54_RS19540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DXE54_RS19545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DXE54_RS19550	COG1127	ABC transporter
DXE54_RS19555	COG0530	calcium, potassium:sodium antiporter activity
DXE54_RS19560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DXE54_RS19560	COG0517	IMP dehydrogenase activity
DXE54_RS19565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DXE54_RS19570	COG3117	lipopolysaccharide transmembrane transporter activity
DXE54_RS19575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DXE54_RS19580	COG1137	ATPase activity
DXE54_RS19585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DXE54_RS19590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DXE54_RS19605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS19610	COG0515	serine threonine protein kinase
DXE54_RS19620	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DXE54_RS19625	COG2198	Histidine kinase
DXE54_RS19625	COG5002	protein histidine kinase activity
DXE54_RS19625	COG0784	Response regulator, receiver
DXE54_RS19630	COG1242	4 iron, 4 sulfur cluster binding
DXE54_RS19635	COG0067	glutamate synthase
DXE54_RS19635	COG0069	glutamate synthase activity
DXE54_RS19635	COG0070	glutamate synthase
DXE54_RS19640	COG0493	'glutamate synthase
DXE54_RS19645	COG4804	nuclease activity
DXE54_RS19650	COG2731	YhcH YjgK YiaL family protein
DXE54_RS19680	COG3069	C4-dicarboxylate transmembrane transporter activity
DXE54_RS19685	COG2969	positive regulation of protein catabolic process
DXE54_RS19690	COG0625	glutathione transferase activity
DXE54_RS19705	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DXE54_RS19710	COG3105	Protein conserved in bacteria
DXE54_RS19715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXE54_RS19720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXE54_RS19760	COG0583	DNA-binding transcription factor activity
DXE54_RS19765	COG0312	modulator of DNA gyrase
DXE54_RS19770	COG3164	Protein of unknown function
DXE54_RS19775	COG1530	ribonuclease E activity
DXE54_RS19780	COG0424	maF-like protein
DXE54_RS19785	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DXE54_RS19790	COG1792	Involved in formation and maintenance of cell shape
DXE54_RS19795	COG1077	Cell shape determining protein MreB Mrl
DXE54_RS19800	COG2200	EAL domain
DXE54_RS19800	COG2199	diguanylate cyclase activity
DXE54_RS19805	COG0604	alcohol dehydrogenase
DXE54_RS19815	COG0511	ligase activity, forming carbon-carbon bonds
DXE54_RS19820	COG0439	Biotin carboxylase
DXE54_RS19825	COG3924	membrane
DXE54_RS19830	COG4145	pantothenate transmembrane transporter activity
DXE54_RS19840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DXE54_RS19850	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DXE54_RS19860	COG1309	transcriptional regulator
DXE54_RS19865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXE54_RS19875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXE54_RS19880	COG4597	amino acid ABC transporter
DXE54_RS19885	COG0765	amino acid transport
DXE54_RS19890	COG1126	abc transporter atp-binding protein
DXE54_RS19930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DXE54_RS19945	COG0009	L-threonylcarbamoyladenylate synthase
DXE54_RS19950	COG0551	DNA topoisomerase type I activity
DXE54_RS19960	COG0758	DNA mediated transformation
DXE54_RS19980	COG0569	domain protein
DXE54_RS19990	COG3036	rescue of stalled ribosome
DXE54_RS19995	COG0789	Transcriptional regulator
DXE54_RS20035	COG0201	protein transport
DXE54_RS20125	COG0089	rRNA binding
DXE54_RS20195	COG2964	Protein conserved in bacteria
DXE54_RS20200	COG0545	Peptidyl-prolyl cis-trans isomerase
DXE54_RS20210	COG1047	Peptidyl-prolyl cis-trans
DXE54_RS20215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DXE54_RS20230	COG0488	(ABC) transporter
DXE54_RS20235	COG0429	hydrolase of the alpha beta-hydrolase fold
DXE54_RS20245	COG3954	Phosphoribulokinase
DXE54_RS20250	COG1765	OsmC-like protein
DXE54_RS20255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXE54_RS20260	COG1289	transmembrane transporter activity
DXE54_RS20265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DXE54_RS20270	COG0512	Glutamine amidotransferase of anthranilate synthase
DXE54_RS20275	COG2184	nucleotidyltransferase activity
DXE54_RS20285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DXE54_RS20295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DXE54_RS20300	COG2146	nitrite reductase [NAD(P)H] activity
DXE54_RS20305	COG2116	formate transmembrane transporter activity
DXE54_RS20320	COG0626	cystathionine gamma-synthase activity
DXE54_RS20335	COG1735	metal-dependent hydrolase with the TIM-barrel fold
DXE54_RS20340	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DXE54_RS20345	COG3457	Alanine racemase
DXE54_RS20355	COG2188	Transcriptional regulator
DXE54_RS20360	COG0180	Tryptophanyl-tRNA synthetase
DXE54_RS20365	COG0546	phosphoglycolate phosphatase activity
DXE54_RS20370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DXE54_RS20375	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DXE54_RS20380	COG3266	domain, Protein
DXE54_RS20395	COG4796	Type ii and iii secretion system protein
DXE54_RS20410	COG3166	PFAM Fimbrial assembly family protein
DXE54_RS20415	COG4972	Pilus assembly protein
DXE54_RS20420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DXE54_RS20425	COG0494	nUDIX hydrolase
DXE54_RS20435	COG1011	Hydrolase
DXE54_RS20440	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DXE54_RS20450	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DXE54_RS20470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DXE54_RS20475	COG2183	response to ionizing radiation
DXE54_RS20480	COG1918	ferrous iron import across plasma membrane
DXE54_RS20485	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DXE54_RS20495	COG5464	transposase or invertase
DXE54_RS20515	COG1040	competence protein
DXE54_RS20525	COG2610	gluconate transmembrane transporter activity
DXE54_RS20530	COG1640	4-alpha-glucanotransferase
DXE54_RS20535	COG0058	SHG alpha-glucan phosphorylase activity
DXE54_RS20560	COG1690	Belongs to the RtcB family
DXE54_RS20565	COG4650	regulator
DXE54_RS20570	COG1349	DNA-binding transcription factor activity
DXE54_RS20585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DXE54_RS20605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DXE54_RS20610	COG0058	SHG alpha-glucan phosphorylase activity
DXE54_RS20630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DXE54_RS20635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DXE54_RS20640	COG2095	MarC family integral membrane protein
DXE54_RS20645	COG2610	gluconate transmembrane transporter activity
DXE54_RS20650	COG3265	gluconokinase activity
DXE54_RS20655	COG1609	Transcriptional regulator
DXE54_RS20660	COG1741	Belongs to the pirin family
DXE54_RS20665	COG0673	inositol 2-dehydrogenase activity
DXE54_RS20670	COG1247	-acetyltransferase
DXE54_RS20675	COG3157	Type VI secretion system effector, Hcp
DXE54_RS20700	COG0405	Gamma-glutamyltransferase
DXE54_RS20710	COG0584	glycerophosphoryl diester phosphodiesterase
DXE54_RS20725	COG1175	transmembrane transport
DXE54_RS20730	COG1653	transport
DXE54_RS20740	COG0410	ABC transporter
DXE54_RS20745	COG0411	ABC transporter
DXE54_RS20750	COG4177	L-phenylalanine transmembrane transporter activity
DXE54_RS20755	COG0559	Belongs to the binding-protein-dependent transport system permease family
DXE54_RS20760	COG0683	leucine binding
DXE54_RS20765	COG0456	acetyltransferase
DXE54_RS20780	COG0683	leucine binding
DXE54_RS20785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DXE54_RS20790	COG2177	Part of the ABC transporter FtsEX involved in
DXE54_RS20795	COG2884	Cell division ATP-binding protein ftsE
DXE54_RS20800	COG0552	protein localization to endoplasmic reticulum
DXE54_RS20805	COG0742	ribosomal rna small subunit methyltransferase
DXE54_RS20810	COG3776	membrane
DXE54_RS20820	COG3714	YhhN family
DXE54_RS20840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DXE54_RS20855	COG0628	permease
DXE54_RS20875	COG0204	Acyl-transferase
DXE54_RS20885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXE54_RS20905	COG1216	Glycosyl transferase, family 2
DXE54_RS20930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXE54_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS20945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXE54_RS20950	COG2091	lysine biosynthetic process via aminoadipic acid
DXE54_RS20955	COG0747	negative chemotaxis
DXE54_RS20960	COG0601	transmembrane transport
DXE54_RS20965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXE54_RS20970	COG0444	Belongs to the ABC transporter superfamily
DXE54_RS20985	COG2188	Transcriptional regulator
DXE54_RS20995	COG3414	Phosphotransferase system galactitol-specific IIB component
DXE54_RS21000	COG3775	system Galactitol-specific IIC component
DXE54_RS21015	COG0191	fructose-bisphosphate aldolase activity
DXE54_RS21030	COG0842	Transport permease protein
DXE54_RS21035	COG1129	ABC transporter
DXE54_RS21035	COG0842	Transport permease protein
DXE54_RS21040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXE54_RS21060	COG2081	HI0933 family
DXE54_RS21065	COG0306	phosphate transporter
DXE54_RS21075	COG0589	response to stress
DXE54_RS21080	COG3104	oligopeptide transport
DXE54_RS21090	COG0339	signal peptide processing
DXE54_RS21095	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DXE54_RS21100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DXE54_RS21110	COG1393	Belongs to the ArsC family
DXE54_RS21120	COG3065	identical protein binding
DXE54_RS21125	COG2197	response regulator
DXE54_RS21130	COG3720	iron ion transport
DXE54_RS21135	COG4771	TonB-dependent receptor
DXE54_RS21140	COG4558	Periplasmic binding protein
DXE54_RS21150	COG3721	Heme iron utilization protein
DXE54_RS21160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXE54_RS21170	COG1285	pathogenesis
DXE54_RS21185	COG3247	response to pH
DXE54_RS21190	COG2771	luxR family
DXE54_RS21200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXE54_RS21205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DXE54_RS21210	COG2207	Transcriptional regulator
DXE54_RS21215	COG2207	Transcriptional regulator
DXE54_RS21220	COG0076	glutamate decarboxylase activity
DXE54_RS21225	COG1858	cytochrome C peroxidase
DXE54_RS21235	COG2197	response regulator
DXE54_RS21240	COG0583	DNA-binding transcription factor activity
DXE54_RS21245	COG1295	ribonuclease BN
DXE54_RS21250	COG0477	Major facilitator Superfamily
DXE54_RS21255	COG2982	Protein involved in outer membrane biogenesis
DXE54_RS21260	COG2200	EAL domain
DXE54_RS21270	COG0612	Peptidase, M16
DXE54_RS21280	COG2200	EAL domain
DXE54_RS21280	COG2199	diguanylate cyclase activity
DXE54_RS21285	COG0457	Tetratricopeptide repeat
DXE54_RS21285	COG3118	belongs to the thioredoxin family
DXE54_RS21290	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DXE54_RS21295	COG1215	transferase activity, transferring glycosyl groups
DXE54_RS21300	COG1215	transferase activity, transferring glycosyl groups
DXE54_RS21320	COG2194	sulfuric ester hydrolase activity
DXE54_RS21330	COG0814	amino acid
DXE54_RS21335	COG4608	Belongs to the ABC transporter superfamily
DXE54_RS21340	COG0444	Belongs to the ABC transporter superfamily
DXE54_RS21345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXE54_RS21350	COG0601	transmembrane transport
DXE54_RS21355	COG0747	negative chemotaxis
DXE54_RS21365	COG2194	sulfuric ester hydrolase activity
DXE54_RS21370	COG3539	Fimbrial protein
DXE54_RS21375	COG3539	Fimbrial protein
DXE54_RS21385	COG3121	Chaperone
DXE54_RS21390	COG3539	Fimbrial protein
DXE54_RS21395	COG2223	nitrite transmembrane transporter activity
DXE54_RS21400	COG5571	outer membrane autotransporter
DXE54_RS21405	COG2818	Glycosylase
DXE54_RS21410	COG0456	acetyltransferase
DXE54_RS21415	COG0243	molybdopterin cofactor binding
DXE54_RS21420	COG2885	chlorophyll binding
DXE54_RS21435	COG2944	sequence-specific DNA binding
DXE54_RS21440	COG1278	Cold shock
DXE54_RS21465	COG3274	enterobacterial common antigen metabolic process
DXE54_RS21470	COG4682	membrane
DXE54_RS21475	COG4682	membrane
DXE54_RS21480	COG1070	Carbohydrate kinase
DXE54_RS21490	COG4213	ABC transporter substrate-binding protein
DXE54_RS21500	COG4214	carbohydrate transport
DXE54_RS21505	COG2207	Transcriptional regulator
DXE54_RS21505	COG1609	Transcriptional regulator
DXE54_RS21510	COG2992	FlgJ-related protein
DXE54_RS21515	COG0366	Alpha amylase catalytic
DXE54_RS21520	COG3977	Valine--pyruvate aminotransferase
DXE54_RS21525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXE54_RS21530	COG1414	Transcriptional regulator
DXE54_RS21540	COG2211	Major facilitator Superfamily
DXE54_RS21550	COG3713	MltA-interacting MipA family protein
DXE54_RS21555	COG0583	DNA-binding transcription factor activity
DXE54_RS21560	COG1566	PFAM secretion protein HlyD family protein
DXE54_RS21570	COG1012	belongs to the aldehyde dehydrogenase family
DXE54_RS21580	COG1454	alcohol dehydrogenase
DXE54_RS21585	COG3276	selenocysteine insertion sequence binding
DXE54_RS21595	COG0625	glutathione transferase activity
DXE54_RS21600	COG1566	PFAM secretion protein HlyD family protein
DXE54_RS21610	COG2213	PTS system mannitol-specific
DXE54_RS21610	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS21620	COG3722	fumarate hydratase activity
DXE54_RS21640	COG5295	Hep Hag repeat protein
DXE54_RS21645	COG1620	l-lactate permease
DXE54_RS21650	COG2186	Transcriptional regulator
DXE54_RS21660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DXE54_RS21665	COG1045	serine acetyltransferase
DXE54_RS21680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DXE54_RS21685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DXE54_RS21695	COG4942	peptidase
DXE54_RS21700	COG2861	carbohydrate metabolic process
DXE54_RS21705	COG1216	Glycosyl transferase, family 2
DXE54_RS21715	COG0156	8-amino-7-oxononanoate synthase activity
DXE54_RS21725	COG0859	PFAM glycosyl transferase family 9
DXE54_RS21730	COG0859	PFAM glycosyl transferase family 9
DXE54_RS21735	COG3307	-O-antigen
DXE54_RS21745	COG1442	glycosyl transferase family 8
DXE54_RS21750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DXE54_RS21765	COG0515	serine threonine protein kinase
DXE54_RS21770	COG0438	transferase activity, transferring glycosyl groups
DXE54_RS21775	COG0859	PFAM glycosyl transferase family 9
DXE54_RS21780	COG1519	Transferase
DXE54_RS21810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DXE54_RS21835	COG1561	YicC-like family, N-terminal region
DXE54_RS21845	COG2860	membrane
DXE54_RS21855	COG0194	GDP metabolic process
DXE54_RS21865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DXE54_RS21870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DXE54_RS21875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DXE54_RS21885	COG0786	glutamate:sodium symporter activity
DXE54_RS21890	COG2233	PERMEase
DXE54_RS21895	COG2982	Protein involved in outer membrane biogenesis
DXE54_RS21900	COG1501	Belongs to the glycosyl hydrolase 31 family
DXE54_RS21905	COG2211	Major facilitator Superfamily
DXE54_RS21915	COG0582	viral genome integration into host DNA
DXE54_RS22025	COG5492	domain, Protein
DXE54_RS22190	COG2814	Major facilitator Superfamily
DXE54_RS22195	COG0697	spore germination
DXE54_RS22200	COG1464	Belongs to the NlpA lipoprotein family
DXE54_RS22210	COG2814	Major facilitator Superfamily
DXE54_RS22240	COG2271	Major facilitator Superfamily
DXE54_RS22245	COG2271	Major facilitator Superfamily
DXE54_RS22250	COG3851	Histidine kinase
DXE54_RS22255	COG2197	response regulator
DXE54_RS22280	COG0440	acetolactate synthase activity
DXE54_RS22285	COG0028	Belongs to the TPP enzyme family
DXE54_RS22300	COG2814	Major facilitator Superfamily
DXE54_RS22305	COG0641	radical SAM
DXE54_RS22315	COG2149	membrane
DXE54_RS22325	COG3119	arylsulfatase activity
DXE54_RS22330	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DXE54_RS22335	COG2207	Transcriptional regulator
DXE54_RS22350	COG2188	Transcriptional regulator
DXE54_RS22370	COG5645	(Lipo)protein
DXE54_RS22375	COG0823	Involved in the tonB-independent uptake of proteins
DXE54_RS22390	COG0561	phosphatase activity
DXE54_RS22395	COG3753	Protein conserved in bacteria
DXE54_RS22400	COG0187	DNA topoisomerase II activity
DXE54_RS22410	COG0592	DNA-directed DNA polymerase activity
DXE54_RS22460	COG0814	amino acid
DXE54_RS22475	COG2091	lysine biosynthetic process via aminoadipic acid
DXE54_RS22480	COG0431	NADPH-dependent FMN reductase
DXE54_RS22485	COG2252	PERMEase
DXE54_RS22490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXE54_RS22525	COG0704	Plays a role in the regulation of phosphate uptake
DXE54_RS22530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DXE54_RS22535	COG0581	inorganic phosphate transmembrane transporter activity
DXE54_RS22540	COG0573	inorganic phosphate transmembrane transporter activity
DXE54_RS22545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DXE54_RS22550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DXE54_RS22600	COG3312	ion transport
DXE54_RS22615	COG0716	FMN binding
DXE54_RS22620	COG1522	sequence-specific DNA binding
DXE54_RS22650	COG1129	ABC transporter
DXE54_RS22655	COG1172	Belongs to the binding-protein-dependent transport system permease family
DXE54_RS22660	COG1879	ABC-type sugar transport system periplasmic component
DXE54_RS22665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXE54_RS22670	COG1609	Transcriptional regulator
DXE54_RS22675	COG0477	Major facilitator Superfamily
DXE54_RS22680	COG2186	Transcriptional regulator
DXE54_RS22720	COG3085	chromosome segregation
DXE54_RS22725	COG0606	chelatase, subunit chli
DXE54_RS22745	COG3978	acetolactate synthase activity
DXE54_RS22750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DXE54_RS22760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DXE54_RS22765	COG0583	DNA-binding transcription factor activity
DXE54_RS22775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DXE54_RS22780	COG3692	DNA binding
DXE54_RS22785	COG0210	DNA helicase
DXE54_RS22800	COG3118	belongs to the thioredoxin family
DXE54_RS22810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DXE54_RS22815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXE54_RS22820	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
DXE54_RS22825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DXE54_RS22830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DXE54_RS22835	COG1088	dTDP-glucose 4,6-dehydratase activity
DXE54_RS22840	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DXE54_RS22845	COG0456	acetyltransferase
DXE54_RS22850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DXE54_RS22855	COG2244	polysaccharide biosynthetic process
DXE54_RS22875	COG1113	amino acid transport
DXE54_RS22900	COG0641	radical SAM
DXE54_RS22905	COG3119	arylsulfatase activity
DXE54_RS22910	COG3071	HemY protein
DXE54_RS22915	COG2959	enzyme of heme biosynthesis
DXE54_RS22920	COG1587	Uroporphyrinogen-III synthase
DXE54_RS22930	COG3072	Adenylate cyclase
DXE54_RS22950	COG5567	small periplasmic lipoprotein
DXE54_RS22960	COG3159	Protein conserved in bacteria
DXE54_RS22970	COG1011	Hydrolase
DXE54_RS22975	COG0210	DNA helicase
DXE54_RS22980	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
DXE54_RS22985	COG3698	Phosphodiester glycosidase
DXE54_RS22990	COG0598	Magnesium transport protein CorA
DXE54_RS23010	COG2962	Rard protein
DXE54_RS23015	COG2050	protein possibly involved in aromatic compounds catabolism
DXE54_RS23020	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
DXE54_RS23025	COG0514	ATP-dependent DNA helicase (RecQ)
DXE54_RS23030	COG1280	lysine exporter protein (LysE YggA)
DXE54_RS23035	COG1280	lysine exporter protein (LysE YggA)
DXE54_RS23040	COG2267	carboxylic ester hydrolase activity
DXE54_RS23045	COG0561	phosphatase activity
DXE54_RS23050	COG0697	spore germination
DXE54_RS23055	COG0583	DNA-binding transcription factor activity
DXE54_RS23085	COG0412	Dienelactone hydrolase
DXE54_RS23090	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DXE54_RS23095	COG1322	Protein conserved in bacteria
DXE54_RS23105	COG3165	ubiquinone biosynthetic process from chorismate
DXE54_RS23115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DXE54_RS23120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DXE54_RS23125	COG0805	protein transport
DXE54_RS23135	COG0250	Participates in transcription elongation, termination and antitermination
DXE54_RS23140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DXE54_RS23145	COG0543	2 iron, 2 sulfur cluster binding
DXE54_RS23165	COG1739	Uncharacterized protein family UPF0029
DXE54_RS23170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DXE54_RS23175	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
DXE54_RS23205	COG1763	Mo-molybdopterin cofactor biosynthetic process
DXE54_RS23210	COG0746	molybdenum cofactor guanylyltransferase activity
DXE54_RS23215	COG3084	Protein conserved in bacteria
DXE54_RS23220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DXE54_RS23225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DXE54_RS23230	COG5339	Protein conserved in bacteria
DXE54_RS23235	COG0204	Acyl-transferase
DXE54_RS23240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXE54_RS23240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXE54_RS23250	COG3078	GTPase activator activity
DXE54_RS23255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DXE54_RS23265	COG2204	response regulator
DXE54_RS23270	COG3852	Histidine kinase
DXE54_RS23275	COG0174	glutamine synthetase
DXE54_RS23280	COG1217	gtp-binding protein TYPA
DXE54_RS23285	COG2188	Transcriptional regulator
DXE54_RS23290	COG1082	Xylose isomerase domain protein TIM barrel
DXE54_RS23295	COG2271	Major facilitator Superfamily
DXE54_RS23305	COG1011	Hydrolase
DXE54_RS23320	COG0456	acetyltransferase
DXE54_RS23330	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DXE54_RS23335	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DXE54_RS23345	COG2864	formate dehydrogenase
DXE54_RS23350	COG0437	4 iron, 4 sulfur cluster binding
DXE54_RS23370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS23370	COG3711	transcriptional antiterminator
DXE54_RS23375	COG1363	Peptidase, m42
DXE54_RS23380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXE54_RS23380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXE54_RS23385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS23420	COG1917	Cupin 2, conserved barrel domain protein
DXE54_RS23420	COG4977	sequence-specific DNA binding
DXE54_RS23430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DXE54_RS23440	COG2258	MOSC domain
DXE54_RS23445	COG2205	protein histidine kinase activity
DXE54_RS23450	COG0745	RESPONSE REGULATOR receiver
DXE54_RS23455	COG3678	ATP-independent chaperone mediated protein folding
DXE54_RS23460	COG4974	Belongs to the 'phage' integrase family
DXE54_RS23530	COG4695	Portal protein
DXE54_RS23620	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS23620	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS23685	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DXE54_RS23705	COG3152	Membrane
DXE54_RS23710	COG3691	Protein conserved in bacteria
DXE54_RS23715	COG0589	response to stress
DXE54_RS23725	COG1494	fructose-1,6-bisphosphatase
DXE54_RS23735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DXE54_RS23760	COG1575	Belongs to the MenA family. Type 1 subfamily
DXE54_RS23775	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DXE54_RS23780	COG1609	Transcriptional regulator
DXE54_RS23785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DXE54_RS23795	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DXE54_RS23805	COG0626	cystathionine gamma-synthase activity
DXE54_RS23810	COG0527	aspartate kinase activity
DXE54_RS23810	COG0460	homoserine dehydrogenase
DXE54_RS23820	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DXE54_RS23830	COG0697	spore germination
DXE54_RS23835	COG3738	Protein conserved in bacteria
DXE54_RS23840	COG0371	Dehydrogenase
DXE54_RS23845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DXE54_RS23850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS23850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS23850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DXE54_RS23855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXE54_RS23860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXE54_RS23865	COG1882	Formate acetyltransferase
DXE54_RS23870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DXE54_RS23875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXE54_RS23880	COG2207	Transcriptional regulator
DXE54_RS23885	COG2194	sulfuric ester hydrolase activity
DXE54_RS23915	COG0583	DNA-binding transcription factor activity
DXE54_RS23925	COG1473	amidohydrolase
DXE54_RS23930	COG0477	Major facilitator Superfamily
DXE54_RS23935	COG1309	transcriptional regulator
DXE54_RS23945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DXE54_RS23950	COG4206	TonB-dependent receptor
DXE54_RS23955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DXE54_RS23980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DXE54_RS23985	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DXE54_RS23985	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DXE54_RS24020	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DXE54_RS24025	COG0250	Participates in transcription elongation, termination and antitermination
DXE54_RS24065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DXE54_RS24075	COG2104	thiamine diphosphate biosynthetic process
DXE54_RS24080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DXE54_RS24115	COG3068	Protein conserved in bacteria
DXE54_RS24130	COG3678	ATP-independent chaperone mediated protein folding
DXE54_RS24135	COG4191	Histidine kinase
DXE54_RS24140	COG2204	response regulator
DXE54_RS24145	COG0151	Belongs to the GarS family
DXE54_RS24175	COG0456	acetyltransferase
DXE54_RS24185	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DXE54_RS24190	COG2224	Isocitrate lyase
DXE54_RS24205	COG1414	Transcriptional regulator
DXE54_RS24210	COG0646	methionine synthase
DXE54_RS24210	COG1410	methionine synthase
DXE54_RS24215	COG1283	sodium-dependent phosphate transmembrane transporter activity
DXE54_RS24260	COG1187	pseudouridine synthase activity
DXE54_RS24275	COG3541	Predicted nucleotidyltransferase
DXE54_RS24285	COG0527	aspartate kinase activity
DXE54_RS24310	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DXE54_RS24330	COG2814	Major facilitator Superfamily
DXE54_RS24330	COG0477	Major facilitator Superfamily
DXE54_RS24335	COG3833	ABC-type maltose transport systems, permease component
DXE54_RS24340	COG1175	transmembrane transport
DXE54_RS24345	COG2182	Extracellular solute-binding protein
DXE54_RS24350	COG3842	ATPase activity
DXE54_RS24365	COG1357	PFAM Pentapeptide repeats (8 copies)
DXE54_RS24385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DXE54_RS24395	COG0534	Mate efflux family protein
DXE54_RS24400	COG3237	CsbD-like
DXE54_RS24405	COG0735	belongs to the Fur family
DXE54_RS24415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DXE54_RS24425	COG0604	alcohol dehydrogenase
DXE54_RS24430	COG0305	Participates in initiation and elongation during chromosome replication
DXE54_RS24435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DXE54_RS24440	COG1448	Aminotransferase
DXE54_RS24450	COG3700	Belongs to the class B bacterial acid phosphatase family
DXE54_RS24455	COG0432	Pfam Uncharacterised protein family UPF0047
DXE54_RS24460	COG2315	Protein conserved in bacteria
DXE54_RS24465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DXE54_RS24470	COG0629	single-stranded DNA binding
DXE54_RS24480	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DXE54_RS24485	COG2207	Transcriptional regulator
DXE54_RS24490	COG0789	Transcriptional regulator
DXE54_RS24495	COG2252	PERMEase
DXE54_RS24500	COG0025	NhaP-type Na H and K H
DXE54_RS24505	COG1357	PFAM Pentapeptide repeats (8 copies)
DXE54_RS24515	COG3162	membrane
DXE54_RS24520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXE54_RS24530	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DXE54_RS24535	COG0437	4 iron, 4 sulfur cluster binding
DXE54_RS24540	COG3301	Polysulphide reductase, NrfD
DXE54_RS24545	COG1138	Cytochrome C-type biogenesis protein
DXE54_RS24550	COG3088	subunit of a heme lyase
DXE54_RS24555	COG4235	cytochrome complex assembly
DXE54_RS24560	COG1301	dicarboxylic acid transport
DXE54_RS24565	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
DXE54_RS24580	COG1289	transmembrane transporter activity
DXE54_RS24585	COG1566	PFAM secretion protein HlyD family protein
DXE54_RS24595	COG2015	COG2015, Alkyl sulfatase and related hydrolases
DXE54_RS24605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXE54_RS24625	COG1172	Belongs to the binding-protein-dependent transport system permease family
DXE54_RS24630	COG1129	ABC transporter
DXE54_RS24650	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DXE54_RS24655	COG0456	acetyltransferase
DXE54_RS24660	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DXE54_RS24665	COG3454	Phosphonate metabolism
DXE54_RS24670	COG4778	phosphonate C-P lyase system protein PhnL
DXE54_RS24675	COG4107	phosphonate C-P lyase system protein PhnK
DXE54_RS24680	COG3627	carbon phosphorus lyase activity
DXE54_RS24685	COG3626	phosphonate metabolism
DXE54_RS24690	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
DXE54_RS24695	COG3624	Phosphonate C-P lyase system protein PhnG
DXE54_RS24700	COG2188	Transcriptional regulator
DXE54_RS24705	COG3639	organic phosphonate transmembrane transporter activity
DXE54_RS24710	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DXE54_RS24715	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DXE54_RS24720	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DXE54_RS24725	COG2824	Alkylphosphonate utilization operon protein PhnA
DXE54_RS24730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DXE54_RS24740	COG0477	Major facilitator Superfamily
DXE54_RS24750	COG0642	Histidine kinase
DXE54_RS24755	COG0745	RESPONSE REGULATOR receiver
DXE54_RS24760	COG2194	sulfuric ester hydrolase activity
DXE54_RS24765	COG0531	amino acid
DXE54_RS24770	COG2207	Transcriptional regulator
DXE54_RS24775	COG1982	Orn Lys Arg decarboxylase major
DXE54_RS24780	COG2169	Transcriptional regulator
DXE54_RS24785	COG1486	melibiose metabolic process
DXE54_RS24800	COG3647	Membrane
DXE54_RS24805	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DXE54_RS24805	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DXE54_RS24810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DXE54_RS24815	COG4565	transcriptional regulatory protein
DXE54_RS24820	COG3290	protein histidine kinase activity
DXE54_RS24825	COG3592	Divergent 4Fe-4S mono-cluster
DXE54_RS24830	COG2388	GCN5-related N-acetyl-transferase
DXE54_RS24845	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DXE54_RS24850	COG3104	oligopeptide transport
DXE54_RS24855	COG1982	Orn Lys Arg decarboxylase major
DXE54_RS24860	COG0531	amino acid
DXE54_RS24865	COG3710	Transcriptional regulator
DXE54_RS24875	COG2020	methyltransferase activity
DXE54_RS24880	COG3468	outer membrane autotransporter barrel domain protein
DXE54_RS24890	COG4983	Phage plasmid primase, P4 family domain protein
DXE54_RS24940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DXE54_RS24945	COG0625	glutathione transferase activity
DXE54_RS24960	COG2271	Major facilitator Superfamily
DXE54_RS25030	COG4372	Transposase
DXE54_RS25035	COG0582	viral genome integration into host DNA
DXE54_RS25045	COG1309	transcriptional regulator
DXE54_RS25050	COG4232	protein-disulfide reductase activity
DXE54_RS25060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DXE54_RS25065	COG1027	Aspartate ammonia-lyase
DXE54_RS25070	COG3030	protein affecting phage T7 exclusion by the F plasmid
DXE54_RS25075	COG0531	amino acid
DXE54_RS25100	COG1509	lysine 2,3-aminomutase activity
DXE54_RS25110	COG5510	response to toxic substance
DXE54_RS25115	COG5510	response to toxic substance
DXE54_RS25120	COG2076	Multidrug Resistance protein
DXE54_RS25125	COG3040	lipid binding
DXE54_RS25145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DXE54_RS25150	COG1053	succinate dehydrogenase
DXE54_RS25160	COG0531	amino acid
DXE54_RS25165	COG1511	domain protein
DXE54_RS25165	COG3264	Mechanosensitive ion channel
DXE54_RS25210	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DXE54_RS25210	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DXE54_RS25215	COG0802	atpase or kinase
DXE54_RS25220	COG0860	N-Acetylmuramoyl-L-alanine amidase
DXE54_RS25240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DXE54_RS25245	COG0330	HflC and HflK could
DXE54_RS25250	COG0330	HflC and HflK could
DXE54_RS25255	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
DXE54_RS25270	COG0557	exoribonuclease II activity
DXE54_RS25275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DXE54_RS25280	COG3789	protein conserved in bacteria
DXE54_RS25285	COG1842	Phage shock protein A
DXE54_RS25295	COG3766	membrane
DXE54_RS25300	COG5463	Belongs to the UPF0441 family
DXE54_RS25305	COG0754	glutathionylspermidine amidase activity
DXE54_RS25310	COG1960	acyl-CoA dehydrogenase activity
DXE54_RS25320	COG3650	response to hydrogen peroxide
DXE54_RS25325	COG1073	alpha beta
DXE54_RS25340	COG3037	sugar-specific permease SgaT UlaA
DXE54_RS25345	COG3414	Phosphotransferase system galactitol-specific IIB component
DXE54_RS25350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXE54_RS25385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DXE54_RS25410	COG0675	Transposase, IS605 OrfB family
DXE54_RS25420	COG3061	Opacity-associated protein A
DXE54_RS25425	COG0545	Peptidyl-prolyl cis-trans isomerase
DXE54_RS25430	COG1113	amino acid transport
DXE54_RS25440	COG0697	spore germination
DXE54_RS25445	COG0702	epimerase
DXE54_RS25450	COG1733	regulation of RNA biosynthetic process
DXE54_RS25455	COG0737	Belongs to the 5'-nucleotidase family
DXE54_RS25460	COG1218	3'(2'),5'-bisphosphate nucleotidase
DXE54_RS25470	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
DXE54_RS25480	COG1253	flavin adenine dinucleotide binding
DXE54_RS25490	COG0729	surface antigen
DXE54_RS25495	COG2911	Protein conserved in bacteria
DXE54_RS25500	COG2105	PFAM AIG2 family protein
DXE54_RS25505	COG2336	PFAM SpoVT AbrB
DXE54_RS25510	COG2337	Toxic component of a toxin-antitoxin (TA) module
DXE54_RS25515	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DXE54_RS25520	COG1879	ABC-type sugar transport system periplasmic component
DXE54_RS25525	COG1129	ABC transporter
DXE54_RS25530	COG1172	Belongs to the binding-protein-dependent transport system permease family
DXE54_RS25535	COG1172	Belongs to the binding-protein-dependent transport system permease family
DXE54_RS25545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DXE54_RS25555	COG0312	modulator of DNA gyrase
DXE54_RS25560	COG3783	Cytochrome b(562)
DXE54_RS25565	COG3077	Addiction module antitoxin, RelB DinJ family
DXE54_RS25570	COG0602	queuosine metabolic process
DXE54_RS25575	COG1328	CTP reductase activity
DXE54_RS25580	COG0366	Alpha amylase catalytic
DXE54_RS25585	COG1263	PTS System
DXE54_RS25585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXE54_RS25590	COG1609	Transcriptional regulator
DXE54_RS25600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DXE54_RS25605	COG0251	oxidation-reduction process
DXE54_RS25625	COG0251	oxidation-reduction process
DXE54_RS25630	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS25635	COG1309	transcriptional regulator
DXE54_RS25640	COG2731	YhcH YjgK YiaL family protein
DXE54_RS25655	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
DXE54_RS25660	COG0456	acetyltransferase
DXE54_RS25665	COG4269	membrane
DXE54_RS25675	COG2927	DNA polymerase III (CHI subunit)
DXE54_RS25685	COG0795	lipopolysaccharide-transporting ATPase activity
DXE54_RS25690	COG0795	lipopolysaccharide-transporting ATPase activity
DXE54_RS25695	COG0433	COG0433 Predicted ATPase
DXE54_RS25700	COG1064	alcohol dehydrogenase
DXE54_RS25755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DXE54_RS25765	COG1205	dead DEAH box helicase
DXE54_RS25765	COG1111	helicase
DXE54_RS25770	COG0210	DNA helicase
DXE54_RS25785	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DXE54_RS25790	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DXE54_RS25795	COG0582	viral genome integration into host DNA
DXE54_RS25800	COG4974	Belongs to the 'phage' integrase family
DXE54_RS25805	COG3539	Fimbrial protein
DXE54_RS25810	COG3539	Fimbrial protein
DXE54_RS25815	COG3121	Chaperone
DXE54_RS25820	COG3188	usher protein
DXE54_RS25825	COG3539	Fimbrial protein
DXE54_RS25830	COG3539	Fimbrial protein
DXE54_RS25835	COG3539	Fimbrial protein
DXE54_RS25840	COG2610	gluconate transmembrane transporter activity
DXE54_RS25850	COG0246	Mannitol dehydrogenase
DXE54_RS25855	COG2186	Transcriptional regulator
DXE54_RS25875	COG0583	DNA-binding transcription factor activity
DXE54_RS25880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DXE54_RS25885	COG0700	Nucleoside recognition
DXE54_RS25890	COG3366	ferrous iron transmembrane transporter activity
DXE54_RS25900	COG1388	LysM domain
DXE54_RS25900	COG1470	cell adhesion involved in biofilm formation
DXE54_RS25905	COG0477	Major facilitator Superfamily
DXE54_RS25910	COG3204	pilus organization
DXE54_RS25925	COG1924	4 iron, 4 sulfur cluster binding
DXE54_RS25930	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DXE54_RS25935	COG2733	membrane
DXE54_RS25940	COG2814	Major facilitator Superfamily
DXE54_RS25950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DXE54_RS25955	COG5457	Domain of unknown function (DUF1127)
DXE54_RS25965	COG0523	cobalamin synthesis protein
DXE54_RS25970	COG2879	small protein
DXE54_RS25975	COG1966	Carbon starvation protein
DXE54_RS25980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DXE54_RS25985	COG2368	4-hydroxyphenylacetate
DXE54_RS26005	COG3971	2-oxopent-4-enoate hydratase activity
DXE54_RS26015	COG3384	dioxygenase
DXE54_RS26020	COG1012	belongs to the aldehyde dehydrogenase family
DXE54_RS26025	COG0179	Fumarylacetoacetate (FAA) hydrolase
DXE54_RS26030	COG1846	Transcriptional regulator
DXE54_RS26035	COG0840	transmembrane signaling receptor activity
DXE54_RS26050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DXE54_RS26055	COG0025	NhaP-type Na H and K H
DXE54_RS26060	COG1802	Transcriptional regulator
DXE54_RS26065	COG1063	alcohol dehydrogenase
DXE54_RS26080	COG1484	DNA-dependent DNA replication
DXE54_RS26095	COG2966	Psort location CytoplasmicMembrane, score
DXE54_RS26100	COG2197	response regulator
DXE54_RS26105	COG2197	response regulator
DXE54_RS26110	COG4114	ferric iron reductase
DXE54_RS26140	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
DXE54_RS26145	COG0456	acetyltransferase
DXE54_RS26150	COG1011	Hydrolase
DXE54_RS26200	COG0740	serine-type endopeptidase activity
DXE54_RS26275	COG5301	cellulose 1,4-beta-cellobiosidase activity
DXE54_RS26280	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DXE54_RS26285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DXE54_RS26310	COG2823	Periplasmic or secreted lipoprotein
DXE54_RS26320	COG4667	esterase of the alpha-beta hydrolase superfamily
DXE54_RS26325	COG0084	hydrolase, TatD family'
DXE54_RS26330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DXE54_RS26335	COG1328	CTP reductase activity
DXE54_RS26370	COG3726	membrane protein affecting hemolysin expression
DXE54_RS26375	COG0560	Phosphoserine phosphatase
DXE54_RS26380	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DXE54_RS26385	COG3172	ATPase kinase involved in NAD metabolism
DXE54_RS26385	COG1056	cytidyltransferase-related domain
DXE54_RS26390	COG1902	pentaerythritol trinitrate reductase activity
DXE54_RS26405	COG1028	Short-chain dehydrogenase reductase Sdr
DXE54_RS26415	COG0583	DNA-binding transcription factor activity
DXE54_RS26420	COG0488	(ABC) transporter
DXE54_RS26425	COG0741	lytic transglycosylase activity
DXE54_RS26445	COG2207	Transcriptional regulator
DXE54_RS26445	COG3708	Transcriptional regulator
DXE54_RS26450	COG3045	CreA protein
DXE54_RS26455	COG0745	RESPONSE REGULATOR receiver
DXE54_RS26460	COG2205	protein histidine kinase activity
DXE54_RS26465	COG4452	Inner membrane protein CreD
DXE54_RS26470	COG0745	RESPONSE REGULATOR receiver
DXE54_RS26480	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA