locus-tag	class	description
GIX96_RS00035	COG0656	L-ascorbic acid biosynthetic process
GIX96_RS00040	COG0583	DNA-binding transcription factor activity
GIX96_RS00050	COG2226	methyltransferase
GIX96_RS00055	COG0741	lytic transglycosylase activity
GIX96_RS00055	COG1388	LysM domain
GIX96_RS00065	COG2226	methyltransferase
GIX96_RS00075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIX96_RS00205	COG5433	transposase activity
GIX96_RS00210	COG3209	COG3209 Rhs family protein
GIX96_RS00225	COG5433	transposase activity
GIX96_RS00230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GIX96_RS00240	COG1960	acyl-CoA dehydrogenase activity
GIX96_RS00250	COG0121	glutamine amidotransferase
GIX96_RS00255	COG3034	peptidoglycan biosynthetic process
GIX96_RS00260	COG3041	Addiction module toxin RelE StbE family
GIX96_RS00265	COG3077	Addiction module antitoxin, RelB DinJ family
GIX96_RS00270	COG0791	NLP P60 protein
GIX96_RS00290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GIX96_RS00295	COG2161	toxin-antitoxin pair type II binding
GIX96_RS00305	COG0454	-acetyltransferase
GIX96_RS00310	COG1690	Belongs to the RtcB family
GIX96_RS00315	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GIX96_RS00320	COG2195	Cleaves the N-terminal amino acid of tripeptides
GIX96_RS00340	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GIX96_RS00410	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GIX96_RS00420	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GIX96_RS00450	COG0582	viral genome integration into host DNA
GIX96_RS00535	COG0583	DNA-binding transcription factor activity
GIX96_RS00540	COG4221	oxidoreductase activity
GIX96_RS00550	COG0583	DNA-binding transcription factor activity
GIX96_RS00565	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GIX96_RS00570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GIX96_RS00575	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GIX96_RS00580	COG2080	2 iron, 2 sulfur cluster binding
GIX96_RS00585	COG3477	response to acidic pH
GIX96_RS00590	COG0727	PFAM Uncharacterised protein family (UPF0153)
GIX96_RS00595	COG3121	Chaperone
GIX96_RS00605	COG3188	usher protein
GIX96_RS00645	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS00650	COG4372	Transposase
GIX96_RS00660	COG1902	pentaerythritol trinitrate reductase activity
GIX96_RS00665	COG1073	alpha beta
GIX96_RS00670	COG0583	DNA-binding transcription factor activity
GIX96_RS00685	COG1388	LysM domain
GIX96_RS00690	COG2207	Transcriptional regulator
GIX96_RS00690	COG3708	Transcriptional regulator
GIX96_RS00700	COG3059	membrane
GIX96_RS00710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GIX96_RS00715	COG2207	Transcriptional regulator
GIX96_RS00720	COG0247	lactate metabolic process
GIX96_RS00725	COG1139	Iron-sulfur cluster binding protein
GIX96_RS00730	COG1556	Lactate utilization protein
GIX96_RS00755	COG2200	EAL domain
GIX96_RS00755	COG2771	luxR family
GIX96_RS00785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GIX96_RS00795	COG2771	luxR family
GIX96_RS00795	COG2200	EAL domain
GIX96_RS00810	COG0666	response to abiotic stimulus
GIX96_RS00820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GIX96_RS00825	COG1304	FMN binding
GIX96_RS00835	COG0549	Belongs to the carbamate kinase family
GIX96_RS00840	COG0402	S-adenosylhomocysteine deaminase activity
GIX96_RS00850	COG1879	ABC-type sugar transport system periplasmic component
GIX96_RS00855	COG1129	ABC transporter
GIX96_RS00860	COG1129	ABC transporter
GIX96_RS00865	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS00875	COG1064	alcohol dehydrogenase
GIX96_RS00890	COG1280	lysine exporter protein (LysE YggA)
GIX96_RS00900	COG3829	transcription factor binding
GIX96_RS00905	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GIX96_RS00910	COG0372	Belongs to the citrate synthase family
GIX96_RS00915	COG2079	MmgE PrpD family protein
GIX96_RS00920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GIX96_RS00925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GIX96_RS00930	COG0402	S-adenosylhomocysteine deaminase activity
GIX96_RS00935	COG0583	DNA-binding transcription factor activity
GIX96_RS00940	COG0288	reversible hydration of carbon dioxide
GIX96_RS00950	COG2807	transmembrane transport
GIX96_RS00955	COG0110	maltose O-acetyltransferase activity
GIX96_RS00960	COG2223	nitrite transmembrane transporter activity
GIX96_RS00965	COG3250	beta-galactosidase activity
GIX96_RS00970	COG1609	Transcriptional regulator
GIX96_RS00980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GIX96_RS00985	COG1414	Transcriptional regulator
GIX96_RS01000	COG0596	Alpha beta hydrolase
GIX96_RS01015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GIX96_RS01020	COG2814	Major facilitator Superfamily
GIX96_RS01025	COG3122	Protein conserved in bacteria
GIX96_RS01030	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GIX96_RS01045	COG3842	ATPase activity
GIX96_RS01055	COG1840	ABC-type Fe3 transport system, periplasmic component
GIX96_RS01060	COG2271	Major facilitator Superfamily
GIX96_RS01075	COG4521	taurine ABC transporter
GIX96_RS01080	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GIX96_RS01085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GIX96_RS01090	COG2175	clavaminate synthase activity
GIX96_RS01095	COG0113	porphobilinogen synthase activity
GIX96_RS01100	COG3468	outer membrane autotransporter barrel domain protein
GIX96_RS01105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GIX96_RS01110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GIX96_RS01115	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GIX96_RS01135	COG1181	Belongs to the D-alanine--D-alanine ligase family
GIX96_RS01145	COG1785	Belongs to the alkaline phosphatase family
GIX96_RS01155	COG3706	GGDEF domain
GIX96_RS01160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GIX96_RS01180	COG4126	flavin adenine dinucleotide binding
GIX96_RS01205	COG1940	carbohydrate kinase activity
GIX96_RS01210	COG2814	Major facilitator Superfamily
GIX96_RS01215	COG0419	ATPase involved in DNA repair
GIX96_RS01220	COG0420	3'-5' exonuclease activity
GIX96_RS01225	COG0745	RESPONSE REGULATOR receiver
GIX96_RS01230	COG5002	protein histidine kinase activity
GIX96_RS01235	COG1114	Component of the transport system for branched-chain amino acids
GIX96_RS01240	COG1113	amino acid transport
GIX96_RS01245	COG0366	Alpha amylase catalytic
GIX96_RS01270	COG1862	Preprotein translocase
GIX96_RS01275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GIX96_RS01280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GIX96_RS01285	COG3609	addiction module antidote protein, CC2985 family
GIX96_RS01295	COG1403	HNH endonuclease
GIX96_RS01300	COG3248	Nucleoside-binding outer membrane protein
GIX96_RS01305	COG4238	major outer membrane lipoprotein
GIX96_RS01315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GIX96_RS01315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GIX96_RS01330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GIX96_RS01335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GIX96_RS01345	COG0667	Aldo Keto reductase
GIX96_RS01355	COG0142	geranyltranstransferase activity
GIX96_RS01370	COG0693	protein deglycase activity
GIX96_RS01375	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GIX96_RS01385	COG2814	Major facilitator Superfamily
GIX96_RS01395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GIX96_RS01400	COG1845	cytochrome c oxidase, subunit III
GIX96_RS01405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GIX96_RS01410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GIX96_RS01415	COG2223	nitrite transmembrane transporter activity
GIX96_RS01420	COG3056	Lipoprotein
GIX96_RS01425	COG0271	Belongs to the BolA IbaG family
GIX96_RS01445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GIX96_RS01450	COG0776	regulation of translation
GIX96_RS01455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GIX96_RS01460	COG1555	photosystem II stabilization
GIX96_RS01465	COG0824	Thioesterase
GIX96_RS01475	COG4533	DNA binding
GIX96_RS01485	COG1522	sequence-specific DNA binding
GIX96_RS01490	COG1132	(ABC) transporter
GIX96_RS01495	COG1132	(ABC) transporter
GIX96_RS01500	COG0347	Belongs to the P(II) protein family
GIX96_RS01505	COG0004	ammonium transporteR
GIX96_RS01510	COG1946	Acyl-CoA thioesterase
GIX96_RS01515	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GIX96_RS01520	COG3695	enzyme binding
GIX96_RS01530	COG5507	3-demethylubiquinone-9 3-methyltransferase
GIX96_RS01535	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GIX96_RS01545	COG0110	maltose O-acetyltransferase activity
GIX96_RS01560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIX96_RS01565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIX96_RS01570	COG1309	transcriptional regulator
GIX96_RS01575	COG3264	Mechanosensitive ion channel
GIX96_RS01575	COG1196	nuclear chromosome segregation
GIX96_RS01585	COG3923	Primosomal replication protein n
GIX96_RS01590	COG2832	Protein of unknown function (DUF454)
GIX96_RS01600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GIX96_RS01635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS01640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GIX96_RS01640	COG4651	solute:proton antiporter activity
GIX96_RS01645	COG2223	nitrite transmembrane transporter activity
GIX96_RS01650	COG0737	Belongs to the 5'-nucleotidase family
GIX96_RS01655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GIX96_RS01660	COG3735	TraB family
GIX96_RS01665	COG3093	addiction module antidote protein HigA
GIX96_RS01670	COG2217	Heavy metal translocating P-type atpase
GIX96_RS01675	COG2066	Belongs to the glutaminase family
GIX96_RS01680	COG0531	amino acid
GIX96_RS01710	COG0789	Transcriptional regulator
GIX96_RS01730	COG1585	Membrane protein implicated in regulation of membrane protease activity
GIX96_RS01735	COG0330	HflC and HflK could
GIX96_RS01740	COG4619	ABC transporter
GIX96_RS01745	COG0390	transport system, permease component
GIX96_RS01750	COG3118	belongs to the thioredoxin family
GIX96_RS01755	COG0300	oxidoreductase activity
GIX96_RS01760	COG2755	lipolytic protein G-D-S-L family
GIX96_RS01765	COG4181	ATPase activity
GIX96_RS01770	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GIX96_RS01775	COG3209	COG3209 Rhs family protein
GIX96_RS01795	COG0583	DNA-binding transcription factor activity
GIX96_RS01805	COG1414	Transcriptional regulator
GIX96_RS01810	COG3960	tartronate-semialdehyde synthase activity
GIX96_RS01815	COG3622	Belongs to the hyi family
GIX96_RS01820	COG2084	Dehydrogenase
GIX96_RS01825	COG1953	Uracil, thiamine, allantoin
GIX96_RS01835	COG2233	PERMEase
GIX96_RS01840	COG1929	Belongs to the glycerate kinase type-1 family
GIX96_RS01845	COG3257	ureidoglycine aminohydrolase activity
GIX96_RS01850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GIX96_RS01855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GIX96_RS01860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GIX96_RS01865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GIX96_RS01875	COG0549	Belongs to the carbamate kinase family
GIX96_RS01880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GIX96_RS01885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GIX96_RS01895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GIX96_RS01905	COG1988	membrane-bound metal-dependent
GIX96_RS01910	COG2501	S4 domain
GIX96_RS01920	COG3539	Fimbrial protein
GIX96_RS01925	COG3121	Chaperone
GIX96_RS01930	COG3188	usher protein
GIX96_RS01935	COG3539	Fimbrial protein
GIX96_RS01940	COG3539	Fimbrial protein
GIX96_RS01945	COG2197	response regulator
GIX96_RS01955	COG2207	Transcriptional regulator
GIX96_RS01965	COG4783	chaperone-mediated protein folding
GIX96_RS01970	COG1215	transferase activity, transferring glycosyl groups
GIX96_RS01975	COG5433	transposase activity
GIX96_RS01985	COG4104	PAAR repeat-containing protein
GIX96_RS01985	COG3209	COG3209 Rhs family protein
GIX96_RS01995	COG4104	PAAR repeat-containing protein
GIX96_RS01995	COG3209	COG3209 Rhs family protein
GIX96_RS02010	COG5002	protein histidine kinase activity
GIX96_RS02015	COG0745	RESPONSE REGULATOR receiver
GIX96_RS02020	COG1538	Outer membrane efflux protein
GIX96_RS02025	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIX96_RS02030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIX96_RS02035	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIX96_RS02040	COG1113	amino acid transport
GIX96_RS02045	COG0668	transmembrane transport
GIX96_RS02050	COG0778	Nitroreductase
GIX96_RS02055	COG2315	Protein conserved in bacteria
GIX96_RS02080	COG2977	Belongs to the P-Pant transferase superfamily
GIX96_RS02085	COG4771	TonB-dependent receptor
GIX96_RS02090	COG2382	esterase
GIX96_RS02095	COG3251	PFAM MbtH domain protein
GIX96_RS02100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GIX96_RS02100	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GIX96_RS02105	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GIX96_RS02110	COG1120	ATPase activity
GIX96_RS02115	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIX96_RS02120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIX96_RS02130	COG4592	Periplasmic binding protein
GIX96_RS02135	COG1169	isochorismate synthase
GIX96_RS02140	COG1021	2,3-dihydroxybenzoate-AMP ligase
GIX96_RS02145	COG1535	isochorismatase
GIX96_RS02145	COG3433	isochorismatase activity
GIX96_RS02150	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS02160	COG1966	Carbon starvation protein
GIX96_RS02165	COG2879	small protein
GIX96_RS02170	COG0371	Dehydrogenase
GIX96_RS02175	COG0436	Aminotransferase
GIX96_RS02180	COG1475	DNA binding
GIX96_RS02185	COG3969	phosphoadenosine phosphosulfate
GIX96_RS02190	COG0583	DNA-binding transcription factor activity
GIX96_RS02195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GIX96_RS02200	COG0450	alkyl hydroperoxide reductase
GIX96_RS02205	COG3634	alkyl hydroperoxide reductase activity
GIX96_RS02210	COG0589	response to stress
GIX96_RS02215	COG1063	alcohol dehydrogenase
GIX96_RS02220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GIX96_RS02225	COG3719	Belongs to the RNase T2 family
GIX96_RS02230	COG0471	metal ion transport
GIX96_RS02235	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GIX96_RS02245	COG3051	citrate lyase alpha subunit
GIX96_RS02250	COG2301	Belongs to the HpcH HpaI aldolase family
GIX96_RS02260	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GIX96_RS02265	COG3290	protein histidine kinase activity
GIX96_RS02270	COG4565	transcriptional regulatory protein
GIX96_RS02275	COG3069	C4-dicarboxylate transmembrane transporter activity
GIX96_RS02295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GIX96_RS02300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GIX96_RS02310	COG0583	DNA-binding transcription factor activity
GIX96_RS02325	COG1686	Belongs to the peptidase S11 family
GIX96_RS02330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GIX96_RS02335	COG0772	Belongs to the SEDS family
GIX96_RS02340	COG0768	penicillin binding
GIX96_RS02350	COG0799	negative regulation of ribosome biogenesis
GIX96_RS02355	COG0406	alpha-ribazole phosphatase activity
GIX96_RS02365	COG1466	dna polymerase III delta subunit
GIX96_RS02380	COG2888	peptidyl-tyrosine sulfation
GIX96_RS02395	COG2214	Heat shock protein DnaJ domain protein
GIX96_RS02400	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GIX96_RS02415	COG0443	Heat shock 70 kDa protein
GIX96_RS02425	COG1126	abc transporter atp-binding protein
GIX96_RS02430	COG0765	amino acid transport
GIX96_RS02435	COG0765	amino acid transport
GIX96_RS02440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIX96_RS02445	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GIX96_RS02450	COG4535	Mg2 and Co2 transporter CorC
GIX96_RS02460	COG1702	phosphate starvation-inducible protein PhoH
GIX96_RS02470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GIX96_RS02510	COG0367	asparagine synthase
GIX96_RS02515	COG0647	UMP catabolic process
GIX96_RS02520	COG1846	Transcriptional regulator
GIX96_RS02520	COG1940	carbohydrate kinase activity
GIX96_RS02525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GIX96_RS02535	COG1263	PTS System
GIX96_RS02535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIX96_RS02535	COG2190	(PTS) system
GIX96_RS02555	COG0735	belongs to the Fur family
GIX96_RS02565	COG0716	FMN binding
GIX96_RS02575	COG0596	Alpha beta hydrolase
GIX96_RS02580	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GIX96_RS02585	COG0033	Phosphoglucomutase
GIX96_RS02590	COG0531	amino acid
GIX96_RS02595	COG1982	Orn Lys Arg decarboxylase major
GIX96_RS02605	COG0745	RESPONSE REGULATOR receiver
GIX96_RS02610	COG2205	protein histidine kinase activity
GIX96_RS02640	COG3209	COG3209 Rhs family protein
GIX96_RS02660	COG3272	Protein of unknown function (DUF1722)
GIX96_RS02665	COG0415	Belongs to the DNA photolyase family
GIX96_RS02670	COG3104	oligopeptide transport
GIX96_RS02675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GIX96_RS02680	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GIX96_RS02685	COG1984	allophanate hydrolase subunit 2
GIX96_RS02695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GIX96_RS02700	COG3180	Ammonia monooxygenase
GIX96_RS02705	COG3539	Fimbrial protein
GIX96_RS02710	COG3121	Chaperone
GIX96_RS02720	COG3539	Fimbrial protein
GIX96_RS02725	COG0372	Belongs to the citrate synthase family
GIX96_RS02735	COG2009	succinate dehydrogenase
GIX96_RS02740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GIX96_RS02745	COG1053	succinate dehydrogenase
GIX96_RS02750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GIX96_RS02755	COG0567	Dehydrogenase, E1 component
GIX96_RS02760	COG0508	dehydrogenase complex catalyzes the overall conversion of
GIX96_RS02770	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GIX96_RS02775	COG0583	DNA-binding transcription factor activity
GIX96_RS02780	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GIX96_RS02785	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GIX96_RS02785	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GIX96_RS02790	COG1301	dicarboxylic acid transport
GIX96_RS02805	COG3799	methylaspartate ammonia-lyase activity
GIX96_RS02810	COG4865	methylaspartate mutase activity
GIX96_RS02820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GIX96_RS02835	COG1271	oxidase subunit
GIX96_RS02840	COG1294	oxidase, subunit
GIX96_RS02845	COG4890	Cyd operon protein YbgT
GIX96_RS02850	COG3790	cyd operon protein YbgE
GIX96_RS02855	COG0824	Thioesterase
GIX96_RS02860	COG0811	peptide transport
GIX96_RS02865	COG0848	biopolymer transport protein
GIX96_RS02870	COG3064	Membrane
GIX96_RS02880	COG2885	chlorophyll binding
GIX96_RS02885	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GIX96_RS02920	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GIX96_RS02925	COG3201	nicotinamide mononucleotide transporter
GIX96_RS02930	COG1230	cation diffusion facilitator family transporter
GIX96_RS02940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GIX96_RS02950	COG2017	converts alpha-aldose to the beta-anomer
GIX96_RS02960	COG1085	galactose-1-phosphate uridylyltransferase
GIX96_RS02965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GIX96_RS02970	COG1119	ATPase activity
GIX96_RS02975	COG2005	Transcriptional regulator
GIX96_RS02975	COG3585	molybdate ion transport
GIX96_RS02985	COG0725	ABC transporter, periplasmic molybdate-binding protein
GIX96_RS02990	COG4149	molybdate abc transporter
GIX96_RS03000	COG0561	phosphatase activity
GIX96_RS03010	COG0583	DNA-binding transcription factor activity
GIX96_RS03015	COG2828	Protein conserved in bacteria
GIX96_RS03020	COG0471	metal ion transport
GIX96_RS03025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GIX96_RS03030	COG4677	pectinesterase activity
GIX96_RS03035	COG0582	viral genome integration into host DNA
GIX96_RS03145	COG3772	lysozyme
GIX96_RS03185	COG0740	serine-type endopeptidase activity
GIX96_RS03260	COG5301	cellulose 1,4-beta-cellobiosidase activity
GIX96_RS03305	COG1881	PFAM PEBP family protein
GIX96_RS03310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GIX96_RS03325	COG2226	methyltransferase
GIX96_RS03330	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GIX96_RS03340	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GIX96_RS03350	COG0521	Mo-molybdopterin cofactor biosynthetic process
GIX96_RS03360	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GIX96_RS03365	COG0314	molybdopterin synthase activity
GIX96_RS03370	COG0670	Belongs to the BI1 family
GIX96_RS03375	COG0670	Belongs to the BI1 family
GIX96_RS03380	COG0392	lysyltransferase activity
GIX96_RS03385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GIX96_RS03390	COG3568	Endonuclease Exonuclease Phosphatase
GIX96_RS03400	COG0842	Transport permease protein
GIX96_RS03405	COG0842	Transport permease protein
GIX96_RS03410	COG1131	(ABC) transporter
GIX96_RS03420	COG1309	transcriptional regulator
GIX96_RS03425	COG0513	Belongs to the DEAD box helicase family
GIX96_RS03435	COG1199	ATP-dependent helicase activity
GIX96_RS03440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GIX96_RS03445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GIX96_RS03455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GIX96_RS03465	COG4774	siderophore transport
GIX96_RS03480	COG0668	transmembrane transport
GIX96_RS03485	COG1126	abc transporter atp-binding protein
GIX96_RS03490	COG0765	amino acid transport
GIX96_RS03495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIX96_RS03505	COG5006	permease, DMT superfamily
GIX96_RS03515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GIX96_RS03520	COG2194	sulfuric ester hydrolase activity
GIX96_RS03530	COG1321	iron dependent repressor
GIX96_RS03535	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GIX96_RS03540	COG1376	ErfK ybiS ycfS ynhG family protein
GIX96_RS03545	COG0488	(ABC) transporter
GIX96_RS03555	COG0561	phosphatase activity
GIX96_RS03565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIX96_RS03570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GIX96_RS03575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GIX96_RS03580	COG0303	'Molybdopterin
GIX96_RS03585	COG1446	asparaginase
GIX96_RS03590	COG1446	asparaginase
GIX96_RS03595	COG4172	Belongs to the ABC transporter superfamily
GIX96_RS03600	COG0747	negative chemotaxis
GIX96_RS03605	COG0601	transmembrane transport
GIX96_RS03615	COG2200	EAL domain
GIX96_RS03620	COG2199	diguanylate cyclase activity
GIX96_RS03645	COG2133	pyrroloquinoline quinone binding
GIX96_RS03650	COG0625	glutathione transferase activity
GIX96_RS03655	COG1686	Belongs to the peptidase S11 family
GIX96_RS03660	COG1349	DNA-binding transcription factor activity
GIX96_RS03665	COG0671	phosphoesterase, PA-phosphatase related
GIX96_RS03670	COG2814	Major facilitator Superfamily
GIX96_RS03680	COG0561	phosphatase activity
GIX96_RS03685	COG0738	Major facilitator superfamily
GIX96_RS03690	COG3226	Transcriptional regulator
GIX96_RS03705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GIX96_RS03715	COG0778	Nitroreductase
GIX96_RS03730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GIX96_RS03735	COG3842	ATPase activity
GIX96_RS03740	COG1176	ABC-type spermidine putrescine transport system, permease component I
GIX96_RS03745	COG1177	transmembrane transport
GIX96_RS03775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIX96_RS03780	COG4160	amino acid transport
GIX96_RS03785	COG4215	(ABC) transporter
GIX96_RS03790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIX96_RS03795	COG1126	abc transporter atp-binding protein
GIX96_RS03820	COG3023	N-Acetylmuramoyl-L-alanine amidase
GIX96_RS03825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GIX96_RS03830	COG0702	epimerase
GIX96_RS03835	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GIX96_RS03840	COG0028	Belongs to the TPP enzyme family
GIX96_RS03845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GIX96_RS03855	COG2431	L-lysine efflux transmembrane transporter activity
GIX96_RS03860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GIX96_RS03865	COG3593	DNA synthesis involved in DNA repair
GIX96_RS03870	COG2990	Protein conserved in bacteria
GIX96_RS03875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIX96_RS03880	COG0577	efflux transmembrane transporter activity
GIX96_RS03880	COG1136	(ABC) transporter
GIX96_RS03885	COG1278	Cold shock
GIX96_RS03895	COG0542	response to heat
GIX96_RS03915	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GIX96_RS03920	COG4988	ABC transporter
GIX96_RS03925	COG0492	ferredoxin-NADP+ reductase activity
GIX96_RS03930	COG1522	sequence-specific DNA binding
GIX96_RS03935	COG1178	ABC-type Fe3 transport system permease component
GIX96_RS03935	COG1674	ftsk spoiiie
GIX96_RS03945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GIX96_RS03955	COG0243	molybdopterin cofactor binding
GIX96_RS03960	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS03965	COG3302	dmso reductase anchor subunit
GIX96_RS03970	COG1335	isochorismatase
GIX96_RS03980	COG0531	amino acid
GIX96_RS03990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIX96_RS03995	COG1882	Formate acetyltransferase
GIX96_RS04000	COG2116	formate transmembrane transporter activity
GIX96_RS04005	COG1944	ATP diphosphatase activity
GIX96_RS04010	COG2323	membrane
GIX96_RS04025	COG0501	Belongs to the peptidase M48B family
GIX96_RS04035	COG0539	negative regulation of cytoplasmic translation
GIX96_RS04045	COG2333	competence protein COMEC
GIX96_RS04045	COG0658	competence protein
GIX96_RS04050	COG1132	(ABC) transporter
GIX96_RS04060	COG3214	Protein conserved in bacteria
GIX96_RS04075	COG3173	Aminoglycoside phosphotransferase
GIX96_RS04080	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GIX96_RS04085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GIX96_RS04095	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GIX96_RS04105	COG2989	Protein conserved in bacteria
GIX96_RS04110	COG3108	Peptidase M15
GIX96_RS04115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GIX96_RS04120	COG1448	Aminotransferase
GIX96_RS04130	COG0017	Asparaginyl-tRNA synthetase
GIX96_RS04140	COG0308	aminopeptidase N
GIX96_RS04145	COG1116	anion transmembrane transporter activity
GIX96_RS04150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GIX96_RS04160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GIX96_RS04165	COG0431	NADPH-dependent FMN reductase
GIX96_RS04170	COG3539	Fimbrial protein
GIX96_RS04175	COG3121	Chaperone
GIX96_RS04185	COG3539	Fimbrial protein
GIX96_RS04190	COG3539	Fimbrial protein
GIX96_RS04195	COG3539	Fimbrial protein
GIX96_RS04215	COG0633	Ferredoxin
GIX96_RS04215	COG3217	Mosc domain protein beta barrel domain protein
GIX96_RS04225	COG0488	(ABC) transporter
GIX96_RS04230	COG2995	paraquat-inducible protein a
GIX96_RS04235	COG3008	intermembrane lipid transfer
GIX96_RS04235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GIX96_RS04240	COG3009	Protein conserved in bacteria
GIX96_RS04245	COG3130	regulation of translation
GIX96_RS04255	COG1067	ATP-dependent peptidase activity
GIX96_RS04265	COG2885	chlorophyll binding
GIX96_RS04265	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GIX96_RS04275	COG3070	regulator of competence-specific genes
GIX96_RS04280	COG1289	transmembrane transporter activity
GIX96_RS04285	COG3304	Inner membrane component domain
GIX96_RS04290	COG0210	DNA helicase
GIX96_RS04305	COG1832	CoA-binding protein
GIX96_RS04320	COG1254	Belongs to the acylphosphatase family
GIX96_RS04325	COG2920	part of a sulfur-relay system
GIX96_RS04330	COG0670	Belongs to the BI1 family
GIX96_RS04410	COG1484	DNA-dependent DNA replication
GIX96_RS04415	COG1846	Transcriptional regulator
GIX96_RS04445	COG1403	HNH endonuclease
GIX96_RS04450	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GIX96_RS04470	COG2207	Transcriptional regulator
GIX96_RS04520	COG3772	lysozyme
GIX96_RS04545	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS04550	COG4372	Transposase
GIX96_RS04555	COG4220	transposase activity
GIX96_RS04630	COG2032	superoxide dismutase activity
GIX96_RS04665	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GIX96_RS04670	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GIX96_RS04675	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
GIX96_RS04680	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GIX96_RS04685	COG1999	signal sequence binding
GIX96_RS04690	COG1773	rubredoxin
GIX96_RS04695	COG1271	oxidase subunit
GIX96_RS04700	COG1294	oxidase, subunit
GIX96_RS04715	COG3206	protein involved in exopolysaccharide biosynthesis
GIX96_RS04715	COG0489	protein tyrosine kinase activity
GIX96_RS04720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GIX96_RS04725	COG1596	polysaccharide export
GIX96_RS04730	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GIX96_RS04750	COG1278	Cold shock
GIX96_RS04755	COG1278	Cold shock
GIX96_RS04775	COG0348	domain, Protein
GIX96_RS04785	COG1879	ABC-type sugar transport system periplasmic component
GIX96_RS04790	COG0745	RESPONSE REGULATOR receiver
GIX96_RS04795	COG3005	denitrification pathway
GIX96_RS04800	COG0243	molybdopterin cofactor binding
GIX96_RS04840	COG3729	General stress protein
GIX96_RS04845	COG2233	PERMEase
GIX96_RS04880	COG1309	transcriptional regulator
GIX96_RS04885	COG0506	proline dehydrogenase activity
GIX96_RS04885	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GIX96_RS04885	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GIX96_RS04895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GIX96_RS04910	COG2822	iron ion transport
GIX96_RS04915	COG2837	iron assimilation
GIX96_RS04920	COG1702	phosphate starvation-inducible protein PhoH
GIX96_RS04925	COG3658	cytochrome
GIX96_RS04930	COG1215	transferase activity, transferring glycosyl groups
GIX96_RS04935	COG1649	PFAM Uncharacterised BCR, COG1649
GIX96_RS04935	COG0726	polysaccharide deacetylase
GIX96_RS04940	COG0457	Tetratricopeptide repeat
GIX96_RS04945	COG3706	GGDEF domain
GIX96_RS04950	COG2200	EAL domain
GIX96_RS04960	COG3710	Transcriptional regulator
GIX96_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS04970	COG3121	Chaperone
GIX96_RS04980	COG3188	usher protein
GIX96_RS04990	COG3539	Fimbrial protein
GIX96_RS05000	COG3210	domain, Protein
GIX96_RS05005	COG2831	hemolysin activation secretion protein
GIX96_RS05010	COG0736	holo-[acyl-carrier-protein] synthase activity
GIX96_RS05020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GIX96_RS05030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GIX96_RS05035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIX96_RS05085	COG0582	viral genome integration into host DNA
GIX96_RS05110	COG4983	Phage plasmid primase, P4 family domain protein
GIX96_RS05130	COG4372	Transposase
GIX96_RS05135	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS05170	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GIX96_RS05175	COG2194	sulfuric ester hydrolase activity
GIX96_RS05185	COG0829	nickel cation binding
GIX96_RS05230	COG0254	rRNA binding
GIX96_RS05255	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS05260	COG4372	Transposase
GIX96_RS05295	COG1358	cellular component organization or biogenesis
GIX96_RS05355	COG4771	TonB-dependent receptor
GIX96_RS05440	COG2831	hemolysin activation secretion protein
GIX96_RS05450	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GIX96_RS05455	COG3969	phosphoadenosine phosphosulfate
GIX96_RS05460	COG1475	DNA binding
GIX96_RS05505	COG3468	outer membrane autotransporter barrel domain protein
GIX96_RS05535	COG2003	Belongs to the UPF0758 family
GIX96_RS05585	COG3381	protein complex oligomerization
GIX96_RS05595	COG1462	curli production assembly transport component CsgG
GIX96_RS05610	COG2197	response regulator
GIX96_RS05635	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GIX96_RS05640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GIX96_RS05655	COG2943	transferase activity, transferring hexosyl groups
GIX96_RS05660	COG5645	(Lipo)protein
GIX96_RS05675	COG1560	Kdo2-lipid A biosynthetic process
GIX96_RS05685	COG2353	YceI-like domain
GIX96_RS05690	COG3038	cytochrome b561
GIX96_RS05725	COG2999	glutathione oxidoreductase activity
GIX96_RS05735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GIX96_RS05745	COG0673	inositol 2-dehydrogenase activity
GIX96_RS05750	COG0728	peptidoglycan biosynthetic process
GIX96_RS05755	COG3418	PFAM FlgN family protein
GIX96_RS05760	COG2747	anti-sigma28 factor FlgM
GIX96_RS05765	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GIX96_RS05770	COG1815	bacterial-type flagellum-dependent cell motility
GIX96_RS05775	COG1558	bacterial-type flagellum-dependent cell motility
GIX96_RS05780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GIX96_RS05785	COG1749	Flagellar hook protein flgE
GIX96_RS05790	COG4787	bacterial-type flagellum-dependent cell motility
GIX96_RS05795	COG4786	Flagellar basal body rod
GIX96_RS05810	COG1705	Flagellar rod assembly protein muramidase FlgJ
GIX96_RS05810	COG3951	Flagellar rod assembly protein muramidase FlgJ
GIX96_RS05815	COG1256	bacterial-type flagellum assembly
GIX96_RS05820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GIX96_RS05825	COG1530	ribonuclease E activity
GIX96_RS05830	COG0564	pseudouridine synthase activity
GIX96_RS05835	COG0424	maF-like protein
GIX96_RS05840	COG1399	metal-binding, possibly nucleic acid-binding protein
GIX96_RS05860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GIX96_RS05865	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS05875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIX96_RS05880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GIX96_RS05885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GIX96_RS05895	COG0470	DNA polymerase III
GIX96_RS05900	COG0084	hydrolase, TatD family'
GIX96_RS05905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIX96_RS05905	COG1263	PTS System
GIX96_RS05910	COG4773	Receptor
GIX96_RS05920	COG0537	adenosine 5'-monophosphoramidase activity
GIX96_RS05925	COG5633	Lipoprotein
GIX96_RS05930	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GIX96_RS05935	COG0510	thiamine kinase activity
GIX96_RS05950	COG1252	NADH dehydrogenase
GIX96_RS05955	COG3134	Outer membrane lipoprotein
GIX96_RS05960	COG1309	transcriptional regulator
GIX96_RS05970	COG1388	LysM domain
GIX96_RS05970	COG1376	ErfK ybiS ycfS ynhG family protein
GIX96_RS05975	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GIX96_RS05980	COG4763	Acyl-transferase
GIX96_RS05985	COG4591	ABC-type transport system involved in lipoprotein release permease component
GIX96_RS05990	COG1136	(ABC) transporter
GIX96_RS05995	COG4591	ABC-type transport system involved in lipoprotein release permease component
GIX96_RS06005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GIX96_RS06010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GIX96_RS06015	COG1177	transmembrane transport
GIX96_RS06025	COG3842	ATPase activity
GIX96_RS06035	COG2850	peptidyl-arginine hydroxylation
GIX96_RS06140	COG1802	Transcriptional regulator
GIX96_RS06140	COG4626	Terminase
GIX96_RS06150	COG2205	protein histidine kinase activity
GIX96_RS06155	COG0745	RESPONSE REGULATOR receiver
GIX96_RS06160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GIX96_RS06170	COG0482	sulfurtransferase activity
GIX96_RS06180	COG1187	pseudouridine synthase activity
GIX96_RS06185	COG0538	isocitrate dehydrogenase activity
GIX96_RS06190	COG0582	viral genome integration into host DNA
GIX96_RS06215	COG2076	Multidrug Resistance protein
GIX96_RS06225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GIX96_RS06245	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GIX96_RS06280	COG5562	phage envelope protein
GIX96_RS06295	COG4220	transposase activity
GIX96_RS06315	COG1030	water channel activity
GIX96_RS06365	COG1196	nuclear chromosome segregation
GIX96_RS06400	COG5301	cellulose 1,4-beta-cellobiosidase activity
GIX96_RS06405	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GIX96_RS06410	COG3546	catalase activity
GIX96_RS06415	COG3685	Protein conserved in bacteria
GIX96_RS06420	COG3685	Protein conserved in bacteria
GIX96_RS06425	COG3729	General stress protein
GIX96_RS06430	COG0500	methyltransferase
GIX96_RS06445	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS06450	COG4372	Transposase
GIX96_RS06460	COG4571	Outer membrane protease
GIX96_RS06490	COG2894	cell division
GIX96_RS06520	COG0179	Fumarylacetoacetate (FAA) hydrolase
GIX96_RS06535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GIX96_RS06540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GIX96_RS06545	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GIX96_RS06560	COG2719	SpoVR family
GIX96_RS06570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GIX96_RS06580	COG1619	proteins homologs of microcin C7 resistance protein MccF
GIX96_RS06595	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GIX96_RS06610	COG0157	Belongs to the NadC ModD family
GIX96_RS06615	COG0500	methyltransferase
GIX96_RS06620	COG1120	ATPase activity
GIX96_RS06625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIX96_RS06630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GIX96_RS06640	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GIX96_RS06650	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GIX96_RS06650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS06650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GIX96_RS06655	COG1461	Dihydroxyacetone kinase
GIX96_RS06660	COG2376	Dihydroxyacetone kinase
GIX96_RS06670	COG0012	GTP binding
GIX96_RS06685	COG0659	secondary active sulfate transmembrane transporter activity
GIX96_RS06690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GIX96_RS06720	COG3094	Invasion gene expression up-regulator, SirB
GIX96_RS06725	COG2912	Transglutaminase-like superfamily
GIX96_RS06745	COG0387	Pfam Sodium calcium exchanger
GIX96_RS06750	COG4572	Cation transport regulator
GIX96_RS06755	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GIX96_RS06760	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GIX96_RS06765	COG4932	domain protein
GIX96_RS06770	COG2197	response regulator
GIX96_RS06775	COG3850	Histidine kinase
GIX96_RS06780	COG2223	nitrite transmembrane transporter activity
GIX96_RS06785	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GIX96_RS06790	COG1140	nitrate reductase beta subunit
GIX96_RS06795	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GIX96_RS06800	COG2181	nitrate reductase activity
GIX96_RS06820	COG0788	formyltetrahydrofolate deformylase activity
GIX96_RS06830	COG1752	Esterase of the alpha-beta hydrolase superfamily
GIX96_RS06835	COG0745	RESPONSE REGULATOR receiver
GIX96_RS06840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GIX96_RS06850	COG1435	thymidine kinase activity
GIX96_RS06855	COG1454	alcohol dehydrogenase
GIX96_RS06855	COG1012	belongs to the aldehyde dehydrogenase family
GIX96_RS06860	COG2095	MarC family integral membrane protein
GIX96_RS06865	COG4166	transmembrane transport
GIX96_RS06870	COG0601	transmembrane transport
GIX96_RS06875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIX96_RS06880	COG0444	Belongs to the ABC transporter superfamily
GIX96_RS06885	COG4608	Belongs to the ABC transporter superfamily
GIX96_RS06905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GIX96_RS06910	COG2350	Protein conserved in bacteria
GIX96_RS06915	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GIX96_RS06920	COG1607	acyl-coa hydrolase
GIX96_RS06940	COG3047	cAMP biosynthetic process
GIX96_RS06945	COG0582	viral genome integration into host DNA
GIX96_RS06955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIX96_RS06995	COG1396	sequence-specific DNA binding
GIX96_RS07020	COG1846	Transcriptional regulator
GIX96_RS07050	COG1403	HNH endonuclease
GIX96_RS07055	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GIX96_RS07100	COG3772	lysozyme
GIX96_RS07245	COG5301	cellulose 1,4-beta-cellobiosidase activity
GIX96_RS07290	COG4372	Transposase
GIX96_RS07295	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS07350	COG3685	Protein conserved in bacteria
GIX96_RS07355	COG3685	Protein conserved in bacteria
GIX96_RS07360	COG3729	General stress protein
GIX96_RS07375	COG0135	phosphoribosylanthranilate isomerase activity
GIX96_RS07375	COG0134	indole-3-glycerol-phosphate synthase activity
GIX96_RS07380	COG0512	Glutamine amidotransferase of anthranilate synthase
GIX96_RS07380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GIX96_RS07385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GIX96_RS07395	COG0613	PHP domain protein
GIX96_RS07400	COG0009	L-threonylcarbamoyladenylate synthase
GIX96_RS07405	COG4907	membrane protein (DUF2207)
GIX96_RS07410	COG1187	pseudouridine synthase activity
GIX96_RS07415	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GIX96_RS07420	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS07425	COG0616	signal peptide processing
GIX96_RS07435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GIX96_RS07440	COG0583	DNA-binding transcription factor activity
GIX96_RS07460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GIX96_RS07470	COG0671	phosphoesterase, PA-phosphatase related
GIX96_RS07475	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GIX96_RS07480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GIX96_RS07490	COG0023	Translation Initiation Factor
GIX96_RS07500	COG1349	DNA-binding transcription factor activity
GIX96_RS07510	COG5001	Diguanylate cyclase
GIX96_RS07520	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GIX96_RS07520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GIX96_RS07525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GIX96_RS07535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIX96_RS07540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIX96_RS07550	COG2814	Major facilitator Superfamily
GIX96_RS07555	COG4172	Belongs to the ABC transporter superfamily
GIX96_RS07560	COG4172	Belongs to the ABC transporter superfamily
GIX96_RS07565	COG4171	peptide transport system, permease
GIX96_RS07570	COG4168	peptide transport system, permease
GIX96_RS07575	COG4166	transmembrane transport
GIX96_RS07585	COG0531	amino acid
GIX96_RS07595	COG0174	glutamine synthetase
GIX96_RS07600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GIX96_RS07605	COG1917	Cupin 2, conserved barrel domain protein
GIX96_RS07605	COG1396	sequence-specific DNA binding
GIX96_RS07610	COG1012	belongs to the aldehyde dehydrogenase family
GIX96_RS07615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GIX96_RS07620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GIX96_RS07625	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GIX96_RS07630	COG1842	Phage shock protein A
GIX96_RS07640	COG1983	PspC domain protein
GIX96_RS07650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GIX96_RS07665	COG1175	transmembrane transport
GIX96_RS07670	COG0395	ABC-type sugar transport system, permease component
GIX96_RS07675	COG1063	alcohol dehydrogenase
GIX96_RS07680	COG1082	Xylose isomerase domain protein TIM barrel
GIX96_RS07685	COG0673	inositol 2-dehydrogenase activity
GIX96_RS07690	COG1554	hydrolase, family 65, central catalytic
GIX96_RS07695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GIX96_RS07700	COG3842	ATPase activity
GIX96_RS07710	COG1609	Transcriptional regulator
GIX96_RS07715	COG3106	COG3106 Predicted ATPase
GIX96_RS07725	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GIX96_RS07730	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GIX96_RS07735	COG4948	Mandelate Racemase Muconate Lactonizing
GIX96_RS07740	COG2866	Carboxypeptidase
GIX96_RS07745	COG0702	epimerase
GIX96_RS07755	COG1073	alpha beta
GIX96_RS07760	COG1073	alpha beta
GIX96_RS07765	COG0583	DNA-binding transcription factor activity
GIX96_RS07770	COG4166	transmembrane transport
GIX96_RS07775	COG0668	transmembrane transport
GIX96_RS07780	COG3182	Iron-regulated membrane protein
GIX96_RS07785	COG0589	response to stress
GIX96_RS07790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GIX96_RS07795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GIX96_RS07815	COG1473	amidohydrolase
GIX96_RS07820	COG1473	amidohydrolase
GIX96_RS07825	COG0583	DNA-binding transcription factor activity
GIX96_RS07830	COG2840	Smr protein MutS2
GIX96_RS07835	COG3706	GGDEF domain
GIX96_RS07850	COG0513	Belongs to the DEAD box helicase family
GIX96_RS07860	COG0582	viral genome integration into host DNA
GIX96_RS07880	COG3723	Recombinational DNA repair protein, rece pathway
GIX96_RS07885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIX96_RS07935	COG3756	Protein conserved in bacteria
GIX96_RS07940	COG1484	DNA-dependent DNA replication
GIX96_RS07945	COG1846	Transcriptional regulator
GIX96_RS08045	COG3772	lysozyme
GIX96_RS08170	COG2032	superoxide dismutase activity
GIX96_RS08185	COG5301	cellulose 1,4-beta-cellobiosidase activity
GIX96_RS08210	COG0589	response to stress
GIX96_RS08220	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GIX96_RS08220	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GIX96_RS08220	COG1013	pyruvate-flavodoxin oxidoreductase activity
GIX96_RS08220	COG0674	pyruvate-flavodoxin oxidoreductase activity
GIX96_RS08225	COG3042	response to heat
GIX96_RS08230	COG3187	Heat shock protein
GIX96_RS08235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GIX96_RS08240	COG2911	Protein conserved in bacteria
GIX96_RS08250	COG3784	Protein of unknown function (DUF1318)
GIX96_RS08265	COG0667	Aldo Keto reductase
GIX96_RS08275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GIX96_RS08280	COG4589	Belongs to the CDS family
GIX96_RS08285	COG2267	carboxylic ester hydrolase activity
GIX96_RS08290	COG2453	phosphatase
GIX96_RS08290	COG0671	phosphoesterase, PA-phosphatase related
GIX96_RS08295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GIX96_RS08300	COG1643	Atp-dependent helicase
GIX96_RS08325	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GIX96_RS08330	COG1012	belongs to the aldehyde dehydrogenase family
GIX96_RS08335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GIX96_RS08340	COG3038	cytochrome b561
GIX96_RS08355	COG0840	transmembrane signaling receptor activity
GIX96_RS08360	COG0583	DNA-binding transcription factor activity
GIX96_RS08365	COG5383	Protein conserved in bacteria
GIX96_RS08375	COG2841	Protein conserved in bacteria
GIX96_RS08385	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GIX96_RS08390	COG1275	C4-dicarboxylate transporter malic acid transport protein
GIX96_RS08395	COG0500	methyltransferase
GIX96_RS08405	COG3135	benzoate transporter
GIX96_RS08410	COG1396	sequence-specific DNA binding
GIX96_RS08415	COG0826	peptidase U32
GIX96_RS08425	COG1724	mRNA binding
GIX96_RS08430	COG1598	PFAM Uncharacterised protein family UPF0150
GIX96_RS08435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GIX96_RS08440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GIX96_RS08445	COG3842	ATPase activity
GIX96_RS08450	COG1176	ABC-type spermidine putrescine transport system, permease component I
GIX96_RS08455	COG1177	transmembrane transport
GIX96_RS08480	COG3238	Protein conserved in bacteria
GIX96_RS08485	COG1247	-acetyltransferase
GIX96_RS08490	COG2130	NADP-dependent
GIX96_RS08495	COG1802	Transcriptional regulator
GIX96_RS08500	COG4772	TonB-dependent receptor
GIX96_RS08505	COG3391	amine dehydrogenase activity
GIX96_RS08510	COG1113	amino acid transport
GIX96_RS08515	COG0625	glutathione transferase activity
GIX96_RS08530	COG3209	COG3209 Rhs family protein
GIX96_RS08560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GIX96_RS08570	COG0384	phenazine biosynthesis protein PhzF
GIX96_RS08575	COG2181	nitrate reductase activity
GIX96_RS08580	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GIX96_RS08585	COG1140	nitrate reductase beta subunit
GIX96_RS08590	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GIX96_RS08595	COG2223	nitrite transmembrane transporter activity
GIX96_RS08600	COG4886	Leucine-rich repeat (LRR) protein
GIX96_RS08605	COG4886	Leucine-rich repeat (LRR) protein
GIX96_RS08620	COG0697	spore germination
GIX96_RS08630	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS08635	COG2864	formate dehydrogenase
GIX96_RS08640	COG3093	addiction module antidote protein HigA
GIX96_RS08645	COG1064	alcohol dehydrogenase
GIX96_RS08665	COG1764	response to oxidative stress
GIX96_RS08670	COG4608	Belongs to the ABC transporter superfamily
GIX96_RS08675	COG0444	Belongs to the ABC transporter superfamily
GIX96_RS08680	COG3706	GGDEF domain
GIX96_RS08685	COG1649	PFAM Uncharacterised BCR, COG1649
GIX96_RS08690	COG0531	amino acid
GIX96_RS08695	COG0076	glutamate decarboxylase activity
GIX96_RS08700	COG0612	Peptidase, M16
GIX96_RS08705	COG4771	TonB-dependent receptor
GIX96_RS08710	COG4178	(ABC) transporter
GIX96_RS08720	COG0641	radical SAM
GIX96_RS08725	COG3119	arylsulfatase activity
GIX96_RS08730	COG2207	Transcriptional regulator
GIX96_RS08740	COG0243	molybdopterin cofactor binding
GIX96_RS08745	COG3539	Fimbrial protein
GIX96_RS08750	COG3539	Fimbrial protein
GIX96_RS08755	COG3539	Fimbrial protein
GIX96_RS08760	COG3188	usher protein
GIX96_RS08770	COG3539	Fimbrial protein
GIX96_RS08790	COG2911	Protein conserved in bacteria
GIX96_RS08790	COG3210	domain, Protein
GIX96_RS08795	COG1070	Carbohydrate kinase
GIX96_RS08805	COG1129	ABC transporter
GIX96_RS08810	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS08815	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS08825	COG1830	Aldolase
GIX96_RS08840	COG3781	membrane
GIX96_RS08850	COG2199	diguanylate cyclase activity
GIX96_RS08860	COG2066	Belongs to the glutaminase family
GIX96_RS08865	COG1012	belongs to the aldehyde dehydrogenase family
GIX96_RS08870	COG0583	DNA-binding transcription factor activity
GIX96_RS08885	COG2814	Major facilitator Superfamily
GIX96_RS08890	COG2095	MarC family integral membrane protein
GIX96_RS08895	COG1846	Transcriptional regulator
GIX96_RS08900	COG4977	sequence-specific DNA binding
GIX96_RS08910	COG0697	spore germination
GIX96_RS08915	COG2814	Major facilitator Superfamily
GIX96_RS08935	COG3706	GGDEF domain
GIX96_RS08940	COG3111	PFAM Bacterial OB fold (BOF) protein
GIX96_RS08945	COG1546	Belongs to the CinA family
GIX96_RS08950	COG0339	signal peptide processing
GIX96_RS08955	COG4221	oxidoreductase activity
GIX96_RS08960	COG1802	Transcriptional regulator
GIX96_RS08970	COG0246	Mannitol dehydrogenase
GIX96_RS08975	COG0477	Major facilitator Superfamily
GIX96_RS09005	COG5301	cellulose 1,4-beta-cellobiosidase activity
GIX96_RS09095	COG1030	water channel activity
GIX96_RS09115	COG4220	transposase activity
GIX96_RS09145	COG3772	lysozyme
GIX96_RS09185	COG2207	Transcriptional regulator
GIX96_RS09200	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GIX96_RS09205	COG1403	HNH endonuclease
GIX96_RS09215	COG3111	PFAM Bacterial OB fold (BOF) protein
GIX96_RS09250	COG1846	Transcriptional regulator
GIX96_RS09310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIX96_RS09335	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS09340	COG4372	Transposase
GIX96_RS09365	COG5301	cellulose 1,4-beta-cellobiosidase activity
GIX96_RS09485	COG3772	lysozyme
GIX96_RS09535	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GIX96_RS09540	COG1403	HNH endonuclease
GIX96_RS09575	COG1484	DNA-dependent DNA replication
GIX96_RS09580	COG1846	Transcriptional regulator
GIX96_RS09635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIX96_RS09665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GIX96_RS09680	COG0243	molybdopterin cofactor binding
GIX96_RS09685	COG0243	molybdopterin cofactor binding
GIX96_RS09690	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS09695	COG3302	dmso reductase anchor subunit
GIX96_RS09700	COG3381	protein complex oligomerization
GIX96_RS09710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GIX96_RS09715	COG1940	carbohydrate kinase activity
GIX96_RS09720	COG0583	DNA-binding transcription factor activity
GIX96_RS09725	COG2814	Major facilitator Superfamily
GIX96_RS09740	COG3591	Belongs to the peptidase S1B family
GIX96_RS09760	COG0628	permease
GIX96_RS09765	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GIX96_RS09770	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GIX96_RS09780	COG0531	amino acid
GIX96_RS09790	COG3136	membrane protein required for alginate biosynthesis
GIX96_RS09795	COG0745	RESPONSE REGULATOR receiver
GIX96_RS09800	COG2205	protein histidine kinase activity
GIX96_RS09810	COG0114	fumarate hydratase activity
GIX96_RS09815	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GIX96_RS09815	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GIX96_RS09820	COG1482	cell wall glycoprotein biosynthetic process
GIX96_RS09825	COG5339	Protein conserved in bacteria
GIX96_RS09845	COG1309	transcriptional regulator
GIX96_RS09850	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS09855	COG1609	Transcriptional regulator
GIX96_RS09860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIX96_RS09860	COG1263	PTS System
GIX96_RS09865	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GIX96_RS09875	COG0673	inositol 2-dehydrogenase activity
GIX96_RS09905	COG4656	Part of a membrane complex involved in electron transport
GIX96_RS09915	COG4659	FMN binding
GIX96_RS09925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GIX96_RS09930	COG3104	oligopeptide transport
GIX96_RS09935	COG0625	glutathione transferase activity
GIX96_RS09940	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GIX96_RS09955	COG3895	Periplasmic Protein
GIX96_RS09965	COG3133	Outer membrane lipoprotein
GIX96_RS09980	COG1566	PFAM secretion protein HlyD family protein
GIX96_RS09985	COG1289	transmembrane transporter activity
GIX96_RS09990	COG2032	superoxide dismutase activity
GIX96_RS09995	COG4989	oxidoreductase activity
GIX96_RS10000	COG3313	Fe-S protein
GIX96_RS10005	COG1309	transcriptional regulator
GIX96_RS10010	COG1902	pentaerythritol trinitrate reductase activity
GIX96_RS10015	COG0346	lactoylglutathione lyase activity
GIX96_RS10025	COG1201	RNA secondary structure unwinding
GIX96_RS10030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GIX96_RS10035	COG0791	NLP P60 protein
GIX96_RS10040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GIX96_RS10045	COG2814	Major facilitator Superfamily
GIX96_RS10060	COG0583	DNA-binding transcription factor activity
GIX96_RS10065	COG2814	Major facilitator Superfamily
GIX96_RS10070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GIX96_RS10075	COG0307	riboflavin synthase, alpha
GIX96_RS10085	COG3468	outer membrane autotransporter barrel domain protein
GIX96_RS10105	COG4529	Protein conserved in bacteria
GIX96_RS10115	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GIX96_RS10120	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS10130	COG2414	aldehyde ferredoxin oxidoreductase
GIX96_RS10135	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS10145	COG0469	pyruvate kinase activity
GIX96_RS10150	COG4238	major outer membrane lipoprotein
GIX96_RS10155	COG1376	ErfK ybiS ycfS ynhG family protein
GIX96_RS10170	COG0719	Fe-S assembly protein
GIX96_RS10175	COG0396	ATPase activity
GIX96_RS10180	COG0719	Fe-S assembly protein
GIX96_RS10185	COG0316	Belongs to the HesB IscA family
GIX96_RS10195	COG2050	protein possibly involved in aromatic compounds catabolism
GIX96_RS10200	COG0247	lactate metabolic process
GIX96_RS10200	COG0277	FAD linked oxidase domain protein
GIX96_RS10205	COG0628	permease
GIX96_RS10220	COG0738	Major facilitator superfamily
GIX96_RS10225	COG2271	Major facilitator Superfamily
GIX96_RS10240	COG4670	ketone body catabolic process
GIX96_RS10245	COG1960	acyl-CoA dehydrogenase activity
GIX96_RS10250	COG2207	Transcriptional regulator
GIX96_RS10250	COG1917	Cupin 2, conserved barrel domain protein
GIX96_RS10255	COG2086	electron transfer activity
GIX96_RS10260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GIX96_RS10265	COG0644	oxidoreductase
GIX96_RS10270	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GIX96_RS10275	COG0318	PFAM AMP-dependent synthetase and ligase
GIX96_RS10280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GIX96_RS10280	COG0574	Belongs to the PEP-utilizing enzyme family
GIX96_RS10290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GIX96_RS10295	COG4256	Hemin uptake protein
GIX96_RS10305	COG2200	EAL domain
GIX96_RS10310	COG0791	NLP P60 protein
GIX96_RS10320	COG0386	Belongs to the glutathione peroxidase family
GIX96_RS10335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GIX96_RS10335	COG0072	phenylalanine-tRNA ligase activity
GIX96_RS10380	COG3137	Salt-induced outer membrane protein
GIX96_RS10385	COG1105	Belongs to the carbohydrate kinase PfkB family
GIX96_RS10395	COG3001	Fructosamine kinase
GIX96_RS10405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GIX96_RS10410	COG1988	membrane-bound metal-dependent
GIX96_RS10415	COG1823	symporter activity
GIX96_RS10430	COG0753	catalase activity
GIX96_RS10440	COG1486	melibiose metabolic process
GIX96_RS10445	COG1917	Cupin 2, conserved barrel domain protein
GIX96_RS10445	COG2169	Transcriptional regulator
GIX96_RS10450	COG1447	Phosphotransferase system cellobiose-specific component IIA
GIX96_RS10455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIX96_RS10460	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIX96_RS10465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GIX96_RS10475	COG0322	excinuclease ABC activity
GIX96_RS10485	COG3678	ATP-independent chaperone mediated protein folding
GIX96_RS10515	COG0708	Exodeoxyribonuclease III
GIX96_RS10520	COG0398	Pfam SNARE associated Golgi protein
GIX96_RS10530	COG0398	Pfam SNARE associated Golgi protein
GIX96_RS10535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GIX96_RS10540	COG4134	Bacterial extracellular solute-binding protein
GIX96_RS10545	COG4135	transport system, permease component
GIX96_RS10550	COG4136	ATPase activity
GIX96_RS10555	COG2897	thiosulfate sulfurtransferase activity
GIX96_RS10560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GIX96_RS10565	COG0494	nUDIX hydrolase
GIX96_RS10575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GIX96_RS10585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GIX96_RS10590	COG0709	Synthesizes selenophosphate from selenide and ATP
GIX96_RS10595	COG0778	Nitroreductase
GIX96_RS10600	COG0616	signal peptide processing
GIX96_RS10610	COG0252	asparaginase activity
GIX96_RS10615	COG1335	isochorismatase
GIX96_RS10620	COG2814	Major facilitator Superfamily
GIX96_RS10630	COG1349	DNA-binding transcription factor activity
GIX96_RS10635	COG0667	Aldo Keto reductase
GIX96_RS10640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS10645	COG0191	fructose-bisphosphate aldolase activity
GIX96_RS10650	COG1063	alcohol dehydrogenase
GIX96_RS10655	COG2271	Major facilitator Superfamily
GIX96_RS10660	COG1063	alcohol dehydrogenase
GIX96_RS10665	COG3139	Protein of unknown function (DUF1315)
GIX96_RS10675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GIX96_RS10680	COG0676	glucose-6-phosphate 1-epimerase activity
GIX96_RS10685	COG0656	L-ascorbic acid biosynthetic process
GIX96_RS10690	COG3713	MltA-interacting MipA family protein
GIX96_RS10695	COG2766	serine protein kinase
GIX96_RS10705	COG2199	diguanylate cyclase activity
GIX96_RS10710	COG2199	diguanylate cyclase activity
GIX96_RS10715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GIX96_RS10730	COG2207	Transcriptional regulator
GIX96_RS10735	COG2807	transmembrane transport
GIX96_RS10740	COG3189	MarR family transcriptional regulator
GIX96_RS10745	COG3042	response to heat
GIX96_RS10765	COG2261	transglycosylase associated protein
GIX96_RS10775	COG3615	Tellurite resistance protein tehB
GIX96_RS10780	COG1280	lysine exporter protein (LysE YggA)
GIX96_RS10785	COG0583	DNA-binding transcription factor activity
GIX96_RS10790	COG0473	3-isopropylmalate dehydrogenase activity
GIX96_RS10795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GIX96_RS10800	COG4638	Rieske (2fe-2S)
GIX96_RS10805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GIX96_RS10810	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GIX96_RS10815	COG0318	PFAM AMP-dependent synthetase and ligase
GIX96_RS10820	COG3065	identical protein binding
GIX96_RS10825	COG1214	PFAM Peptidase M22, glycoprotease
GIX96_RS10830	COG1199	ATP-dependent helicase activity
GIX96_RS10835	COG0251	oxidation-reduction process
GIX96_RS10850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GIX96_RS10860	COG1760	l-serine dehydratase
GIX96_RS10865	COG2200	EAL domain
GIX96_RS10870	COG1253	flavin adenine dinucleotide binding
GIX96_RS10875	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIX96_RS10875	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS10880	COG3715	PTS system
GIX96_RS10885	COG3716	PTS system mannose fructose sorbose family IID component
GIX96_RS10900	COG2226	methyltransferase
GIX96_RS10930	COG1414	Transcriptional regulator
GIX96_RS10935	COG2814	Major facilitator Superfamily
GIX96_RS10945	COG0793	Belongs to the peptidase S41A family
GIX96_RS10955	COG1956	GAF domain-containing protein
GIX96_RS10960	COG2995	paraquat-inducible protein a
GIX96_RS10965	COG3008	intermembrane lipid transfer
GIX96_RS10985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GIX96_RS10995	COG1276	copper resistance
GIX96_RS11000	COG2372	response to copper ion
GIX96_RS11010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GIX96_RS11015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIX96_RS11020	COG1770	oligopeptidase
GIX96_RS11025	COG2979	Protein of unknown function (DUF533)
GIX96_RS11035	COG3141	response to X-ray
GIX96_RS11040	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GIX96_RS11045	COG0800	Aldolase
GIX96_RS11050	COG0129	dihydroxy-acid dehydratase activity
GIX96_RS11055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GIX96_RS11060	COG1737	Transcriptional regulator
GIX96_RS11065	COG0469	pyruvate kinase activity
GIX96_RS11070	COG1560	Kdo2-lipid A biosynthetic process
GIX96_RS11075	COG0739	heme binding
GIX96_RS11080	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GIX96_RS11090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GIX96_RS11120	COG0217	transcriptional regulatory protein
GIX96_RS11125	COG0494	nUDIX hydrolase
GIX96_RS11130	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GIX96_RS11135	COG1335	isochorismatase
GIX96_RS11140	COG1801	Protein of unknown function DUF72
GIX96_RS11145	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GIX96_RS11160	COG0243	molybdopterin cofactor binding
GIX96_RS11165	COG3005	denitrification pathway
GIX96_RS11175	COG3102	Protein conserved in bacteria
GIX96_RS11185	COG3755	Protein conserved in bacteria
GIX96_RS11195	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GIX96_RS11200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GIX96_RS11210	COG0745	RESPONSE REGULATOR receiver
GIX96_RS11215	COG2201	protein-glutamate methylesterase activity
GIX96_RS11220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GIX96_RS11225	COG0840	transmembrane signaling receptor activity
GIX96_RS11230	COG0840	transmembrane signaling receptor activity
GIX96_RS11235	COG0835	chemotaxis
GIX96_RS11240	COG0643	Histidine kinase
GIX96_RS11240	COG2198	Histidine kinase
GIX96_RS11245	COG1360	Flagellar Motor Protein
GIX96_RS11250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GIX96_RS11265	COG0589	response to stress
GIX96_RS11270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GIX96_RS11275	COG1877	trehalose-phosphatase activity
GIX96_RS11285	COG1129	ABC transporter
GIX96_RS11290	COG1879	ABC-type sugar transport system periplasmic component
GIX96_RS11295	COG1528	Iron-storage protein
GIX96_RS11315	COG1528	Iron-storage protein
GIX96_RS11325	COG0814	amino acid
GIX96_RS11330	COG3318	Belongs to the UPF0149 family
GIX96_RS11330	COG3012	SEC-C Motif Domain Protein
GIX96_RS11360	COG2197	response regulator
GIX96_RS11375	COG2197	response regulator
GIX96_RS11380	COG1126	abc transporter atp-binding protein
GIX96_RS11385	COG0765	amino acid transport
GIX96_RS11395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIX96_RS11405	COG1191	sigma factor activity
GIX96_RS11415	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GIX96_RS11420	COG1516	flagellar protein fliS
GIX96_RS11430	COG0366	Alpha amylase catalytic
GIX96_RS11440	COG2391	methyltransferase activity
GIX96_RS11445	COG0425	Belongs to the sulfur carrier protein TusA family
GIX96_RS11450	COG2135	peptidase activity
GIX96_RS11455	COG0454	-acetyltransferase
GIX96_RS11465	COG0454	-acetyltransferase
GIX96_RS11480	COG1766	The M ring may be actively involved in energy transduction
GIX96_RS11485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GIX96_RS11490	COG1317	bacterial-type flagellum organization
GIX96_RS11495	COG1157	protein secretion by the type III secretion system
GIX96_RS11500	COG2882	bacterial-type flagellum organization
GIX96_RS11505	COG3144	bacterial-type flagellum assembly
GIX96_RS11510	COG1580	Controls the rotational direction of flagella during chemotaxis
GIX96_RS11515	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GIX96_RS11520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GIX96_RS11525	COG3190	flagellar
GIX96_RS11530	COG1338	Plays a role in the flagellum-specific transport system
GIX96_RS11535	COG1987	bacterial-type flagellum assembly
GIX96_RS11540	COG1684	flagellar biosynthetic protein fliR
GIX96_RS11545	COG2197	response regulator
GIX96_RS11565	COG3706	GGDEF domain
GIX96_RS11570	COG5475	Uncharacterized small protein (DUF2158)
GIX96_RS11575	COG2354	Protein conserved in bacteria
GIX96_RS11580	COG0697	spore germination
GIX96_RS11585	COG3727	T/G mismatch-specific endonuclease activity
GIX96_RS11590	COG0270	DNA (cytosine-5-)-methyltransferase activity
GIX96_RS11595	COG1418	mRNA catabolic process
GIX96_RS11615	COG2205	protein histidine kinase activity
GIX96_RS11620	COG0745	RESPONSE REGULATOR receiver
GIX96_RS11625	COG2351	hydroxyisourate hydrolase activity
GIX96_RS11640	COG3443	Belongs to the bacterial solute-binding protein 9 family
GIX96_RS11645	COG3038	cytochrome b561
GIX96_RS11665	COG5301	cellulose 1,4-beta-cellobiosidase activity
GIX96_RS11755	COG4220	transposase activity
GIX96_RS11785	COG3772	lysozyme
GIX96_RS11840	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GIX96_RS11845	COG1403	HNH endonuclease
GIX96_RS11890	COG1846	Transcriptional regulator
GIX96_RS11935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIX96_RS11985	COG0477	Major facilitator Superfamily
GIX96_RS11990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GIX96_RS11995	COG0217	transcriptional regulatory protein
GIX96_RS12015	COG0583	DNA-binding transcription factor activity
GIX96_RS12020	COG0583	DNA-binding transcription factor activity
GIX96_RS12030	COG1376	ErfK ybiS ycfS ynhG family protein
GIX96_RS12045	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
GIX96_RS12055	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS12060	COG4372	Transposase
GIX96_RS12065	COG4771	TonB-dependent receptor
GIX96_RS12105	COG2003	Belongs to the UPF0758 family
GIX96_RS12140	COG4917	ethanolamine utilization protein
GIX96_RS12150	COG1289	transmembrane transporter activity
GIX96_RS12160	COG1686	Belongs to the peptidase S11 family
GIX96_RS12165	COG2925	Exonuclease
GIX96_RS12170	COG0425	Belongs to the sulfur carrier protein TusA family
GIX96_RS12175	COG2391	methyltransferase activity
GIX96_RS12180	COG0531	amino acid
GIX96_RS12190	COG0583	DNA-binding transcription factor activity
GIX96_RS12195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GIX96_RS12210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GIX96_RS12220	COG0131	Imidazoleglycerol-phosphate dehydratase
GIX96_RS12220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GIX96_RS12225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GIX96_RS12250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GIX96_RS12255	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GIX96_RS12265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GIX96_RS12270	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GIX96_RS12270	COG0662	Cupin 2, conserved barrel domain protein
GIX96_RS12275	COG1051	belongs to the nudix hydrolase family
GIX96_RS12280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GIX96_RS12285	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GIX96_RS12295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GIX96_RS12320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GIX96_RS12325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GIX96_RS12335	COG0438	transferase activity, transferring glycosyl groups
GIX96_RS12340	COG2327	Polysaccharide pyruvyl transferase
GIX96_RS12345	COG2244	polysaccharide biosynthetic process
GIX96_RS12350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GIX96_RS12355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GIX96_RS12360	COG0662	Cupin 2, conserved barrel domain protein
GIX96_RS12360	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GIX96_RS12365	COG0297	glycogen (starch) synthase activity
GIX96_RS12370	COG1051	belongs to the nudix hydrolase family
GIX96_RS12375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GIX96_RS12380	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GIX96_RS12385	COG0110	maltose O-acetyltransferase activity
GIX96_RS12390	COG1216	Glycosyl transferase, family 2
GIX96_RS12400	COG0438	transferase activity, transferring glycosyl groups
GIX96_RS12405	COG1045	serine acetyltransferase
GIX96_RS12410	COG0463	Glycosyl transferase, family 2
GIX96_RS12415	COG3206	protein involved in exopolysaccharide biosynthesis
GIX96_RS12415	COG0489	protein tyrosine kinase activity
GIX96_RS12420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GIX96_RS12425	COG1596	polysaccharide export
GIX96_RS12430	COG1253	flavin adenine dinucleotide binding
GIX96_RS12445	COG2982	Protein involved in outer membrane biogenesis
GIX96_RS12455	COG0572	uridine kinase
GIX96_RS12465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GIX96_RS12470	COG0443	Heat shock 70 kDa protein
GIX96_RS12475	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
GIX96_RS12480	COG0631	protein serine/threonine phosphatase activity
GIX96_RS12485	COG4245	von Willebrand factor, type A
GIX96_RS12510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIX96_RS12525	COG2205	protein histidine kinase activity
GIX96_RS12530	COG0745	RESPONSE REGULATOR receiver
GIX96_RS12535	COG3422	double-strand break repair
GIX96_RS12540	COG0826	peptidase U32
GIX96_RS12585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GIX96_RS12600	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GIX96_RS12695	COG4695	Portal protein
GIX96_RS12760	COG4974	Belongs to the 'phage' integrase family
GIX96_RS12780	COG1063	alcohol dehydrogenase
GIX96_RS12785	COG3775	system Galactitol-specific IIC component
GIX96_RS12790	COG3414	Phosphotransferase system galactitol-specific IIB component
GIX96_RS12795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS12810	COG1830	Aldolase
GIX96_RS12815	COG2211	Major facilitator Superfamily
GIX96_RS12820	COG1397	ADP-ribosylglycohydrolase
GIX96_RS12825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS12830	COG2188	Transcriptional regulator
GIX96_RS12835	COG3757	hydrolase, family 25
GIX96_RS12840	COG0351	phosphomethylpyrimidine kinase
GIX96_RS12875	COG5455	response to cobalt ion
GIX96_RS12880	COG3539	Fimbrial protein
GIX96_RS12890	COG3121	Chaperone
GIX96_RS12895	COG3539	Fimbrial protein
GIX96_RS12905	COG0489	protein tyrosine kinase activity
GIX96_RS12920	COG3831	ATPase activity
GIX96_RS12925	COG3831	ATPase activity
GIX96_RS12930	COG3831	ATPase activity
GIX96_RS12940	COG0714	Associated with various cellular activities
GIX96_RS12945	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GIX96_RS12950	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GIX96_RS12955	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GIX96_RS12960	COG4715	Zinc finger, swim domain protein
GIX96_RS12965	COG4808	Protein conserved in bacteria
GIX96_RS12970	COG4807	Protein conserved in bacteria
GIX96_RS12975	COG3279	Response regulator of the LytR AlgR family
GIX96_RS12980	COG3275	phosphorelay sensor kinase activity
GIX96_RS12995	COG5301	cellulose 1,4-beta-cellobiosidase activity
GIX96_RS13075	COG0740	serine-type endopeptidase activity
GIX96_RS13125	COG3772	lysozyme
GIX96_RS13350	COG0582	viral genome integration into host DNA
GIX96_RS13355	COG0789	Transcriptional regulator
GIX96_RS13365	COG1174	glycine betaine transport
GIX96_RS13370	COG1125	glycine betaine transport
GIX96_RS13375	COG1174	glycine betaine transport
GIX96_RS13380	COG1732	Glycine betaine
GIX96_RS13385	COG1472	Belongs to the glycosyl hydrolase 3 family
GIX96_RS13390	COG0277	FAD linked oxidase domain protein
GIX96_RS13395	COG1686	Belongs to the peptidase S11 family
GIX96_RS13405	COG0586	Pfam SNARE associated Golgi protein
GIX96_RS13410	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS13415	COG1538	Outer membrane efflux protein
GIX96_RS13425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GIX96_RS13430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GIX96_RS13435	COG0625	glutathione transferase activity
GIX96_RS13450	COG2271	Major facilitator Superfamily
GIX96_RS13465	COG1346	cytolysis
GIX96_RS13475	COG2949	membrane
GIX96_RS13485	COG0493	'glutamate synthase
GIX96_RS13490	COG0167	dihydroorotate dehydrogenase activity
GIX96_RS13490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GIX96_RS13495	COG4211	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS13500	COG1129	ABC transporter
GIX96_RS13505	COG1879	ABC-type sugar transport system periplasmic component
GIX96_RS13510	COG1609	Transcriptional regulator
GIX96_RS13515	COG2311	Membrane
GIX96_RS13525	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GIX96_RS13530	COG4771	TonB-dependent receptor
GIX96_RS13535	COG0833	amino acid
GIX96_RS13540	COG0583	DNA-binding transcription factor activity
GIX96_RS13545	COG2855	membrane
GIX96_RS13555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS13555	COG1522	sequence-specific DNA binding
GIX96_RS13560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GIX96_RS13570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GIX96_RS13575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GIX96_RS13580	COG2313	pseudouridylate synthase activity
GIX96_RS13585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS13590	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GIX96_RS13590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIX96_RS13590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIX96_RS13595	COG1105	Belongs to the carbohydrate kinase PfkB family
GIX96_RS13600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS13600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS13605	COG2814	Major facilitator Superfamily
GIX96_RS13620	COG0246	Mannitol dehydrogenase
GIX96_RS13625	COG0523	cobalamin synthesis protein
GIX96_RS13630	COG0671	phosphoesterase, PA-phosphatase related
GIX96_RS13635	COG0791	NLP P60 protein
GIX96_RS13640	COG2200	EAL domain
GIX96_RS13645	COG4166	transmembrane transport
GIX96_RS13650	COG4174	ABC transporter (Permease)
GIX96_RS13655	COG4239	(ABC) transporter, permease
GIX96_RS13660	COG4172	Belongs to the ABC transporter superfamily
GIX96_RS13670	COG2814	Major facilitator Superfamily
GIX96_RS13675	COG1187	pseudouridine synthase activity
GIX96_RS13680	COG1061	Type III restriction enzyme res subunit
GIX96_RS13700	COG3083	sulfuric ester hydrolase activity
GIX96_RS13710	COG3468	outer membrane autotransporter barrel domain protein
GIX96_RS13715	COG2197	response regulator
GIX96_RS13720	COG4235	cytochrome complex assembly
GIX96_RS13720	COG3088	subunit of a heme lyase
GIX96_RS13725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GIX96_RS13730	COG1138	Cytochrome C-type biogenesis protein
GIX96_RS13740	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GIX96_RS13745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GIX96_RS13750	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GIX96_RS13755	COG4133	protoheme IX ABC transporter activity
GIX96_RS13760	COG3005	denitrification pathway
GIX96_RS13765	COG3043	anaerobic respiration
GIX96_RS13770	COG0348	domain, Protein
GIX96_RS13775	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS13785	COG3062	negative regulation of establishment of protein localization
GIX96_RS13790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS13790	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS13805	COG4615	Cyclic peptide transporter
GIX96_RS13810	COG3145	DNA-N1-methyladenine dioxygenase activity
GIX96_RS13815	COG2169	Transcriptional regulator
GIX96_RS13815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GIX96_RS13820	COG1477	protein flavinylation
GIX96_RS13825	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GIX96_RS13830	COG0642	Histidine kinase
GIX96_RS13830	COG2198	Histidine kinase
GIX96_RS13835	COG2197	response regulator
GIX96_RS13840	COG2205	protein histidine kinase activity
GIX96_RS13840	COG0784	Response regulator, receiver
GIX96_RS13845	COG4676	Protein conserved in bacteria
GIX96_RS13855	COG2373	Large extracellular alpha-helical protein
GIX96_RS13860	COG3234	Protein of unknown function (DUF1175)
GIX96_RS13865	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
GIX96_RS13870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GIX96_RS13880	COG3468	outer membrane autotransporter barrel domain protein
GIX96_RS13885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GIX96_RS13890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GIX96_RS13895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GIX96_RS13900	COG3642	lipopolysaccharide core region biosynthetic process
GIX96_RS13905	COG2814	Major facilitator Superfamily
GIX96_RS13910	COG0583	DNA-binding transcription factor activity
GIX96_RS13920	COG0584	glycerophosphoryl diester phosphodiesterase
GIX96_RS13925	COG2271	Major facilitator Superfamily
GIX96_RS13930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GIX96_RS13940	COG0247	lactate metabolic process
GIX96_RS13945	COG5464	transposase or invertase
GIX96_RS13950	COG3836	Belongs to the HpcH HpaI aldolase family
GIX96_RS13965	COG2271	Major facilitator Superfamily
GIX96_RS13970	COG4948	Mandelate Racemase Muconate Lactonizing
GIX96_RS13975	COG1414	Transcriptional regulator
GIX96_RS13995	COG0406	alpha-ribazole phosphatase activity
GIX96_RS14040	COG0318	PFAM AMP-dependent synthetase and ligase
GIX96_RS14050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GIX96_RS14065	COG1169	isochorismate synthase
GIX96_RS14070	COG4575	ribosome binding
GIX96_RS14075	COG2153	protein acetylation
GIX96_RS14080	COG1234	tRNA 3'-trailer cleavage
GIX96_RS14085	COG5160	protein modification by small protein removal
GIX96_RS14105	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GIX96_RS14110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GIX96_RS14120	COG0839	Belongs to the complex I subunit 6 family
GIX96_RS14135	COG1034	ATP synthesis coupled electron transport
GIX96_RS14140	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GIX96_RS14145	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GIX96_RS14165	COG0583	DNA-binding transcription factor activity
GIX96_RS14170	COG0436	Aminotransferase
GIX96_RS14180	COG0471	metal ion transport
GIX96_RS14180	COG0490	domain, Protein
GIX96_RS14185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GIX96_RS14200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GIX96_RS14205	COG0280	phosphate acetyltransferase
GIX96_RS14205	COG0857	belongs to the CobB CobQ family
GIX96_RS14210	COG1288	antiporter activity
GIX96_RS14215	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GIX96_RS14220	COG0622	Phosphoesterase
GIX96_RS14225	COG0625	glutathione transferase activity
GIX96_RS14230	COG0625	glutathione transferase activity
GIX96_RS14235	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GIX96_RS14240	COG1090	epimerase
GIX96_RS14245	COG5464	transposase or invertase
GIX96_RS14250	COG4598	ABC transporter
GIX96_RS14255	COG4160	amino acid transport
GIX96_RS14260	COG4215	(ABC) transporter
GIX96_RS14265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIX96_RS14270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIX96_RS14275	COG0163	prenyltransferase activity
GIX96_RS14280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GIX96_RS14285	COG1286	toxin biosynthetic process
GIX96_RS14290	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GIX96_RS14295	COG0285	dihydrofolate synthase activity
GIX96_RS14305	COG0586	Pfam SNARE associated Golgi protein
GIX96_RS14315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GIX96_RS14330	COG2814	Major facilitator Superfamily
GIX96_RS14335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIX96_RS14340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GIX96_RS14340	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GIX96_RS14350	COG3101	peptidyl-lysine hydroxylation
GIX96_RS14355	COG0730	response to heat
GIX96_RS14385	COG3539	Fimbrial protein
GIX96_RS14390	COG3539	Fimbrial protein
GIX96_RS14395	COG3539	Fimbrial protein
GIX96_RS14400	COG3121	Chaperone
GIX96_RS14405	COG3188	usher protein
GIX96_RS14410	COG3539	Fimbrial protein
GIX96_RS14415	COG2062	phosphohistidine phosphatase, SixA
GIX96_RS14420	COG1024	Enoyl-CoA hydratase
GIX96_RS14420	COG1250	3-hydroxyacyl-CoA dehydrogenase
GIX96_RS14430	COG3691	Protein conserved in bacteria
GIX96_RS14435	COG2067	long-chain fatty acid transport protein
GIX96_RS14445	COG2853	Lipoprotein
GIX96_RS14450	COG2116	formate transmembrane transporter activity
GIX96_RS14460	COG0582	viral genome integration into host DNA
GIX96_RS14535	COG0477	Major facilitator Superfamily
GIX96_RS14540	COG1566	PFAM secretion protein HlyD family protein
GIX96_RS14545	COG2197	response regulator
GIX96_RS14550	COG2198	Histidine kinase
GIX96_RS14550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIX96_RS14550	COG0784	Response regulator, receiver
GIX96_RS14550	COG2205	protein histidine kinase activity
GIX96_RS14560	COG0679	Auxin Efflux Carrier
GIX96_RS14565	COG0028	Belongs to the TPP enzyme family
GIX96_RS14590	COG1560	Kdo2-lipid A biosynthetic process
GIX96_RS14600	COG0436	Aminotransferase
GIX96_RS14605	COG3275	phosphorelay sensor kinase activity
GIX96_RS14610	COG3279	Response regulator of the LytR AlgR family
GIX96_RS14615	COG2207	Transcriptional regulator
GIX96_RS14620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS14620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS14620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GIX96_RS14625	COG1363	Peptidase, m42
GIX96_RS14630	COG0006	proline dipeptidase activity
GIX96_RS14635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIX96_RS14640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIX96_RS14665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GIX96_RS14670	COG2199	diguanylate cyclase activity
GIX96_RS14670	COG2200	EAL domain
GIX96_RS14685	COG3415	Transposase
GIX96_RS14690	COG3415	Transposase
GIX96_RS14695	COG0675	Transposase, IS605 OrfB family
GIX96_RS14740	COG0385	Bile acid
GIX96_RS14745	COG3530	Putative quorum-sensing-regulated virulence factor
GIX96_RS14765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GIX96_RS14770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS14775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GIX96_RS14780	COG2190	(PTS) system
GIX96_RS14795	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GIX96_RS14800	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GIX96_RS14805	COG4208	sulfate ABC transporter
GIX96_RS14810	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GIX96_RS14815	COG4150	thiosulfate binding
GIX96_RS14820	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS14835	COG1263	PTS System
GIX96_RS14835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIX96_RS14840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GIX96_RS14845	COG2837	iron assimilation
GIX96_RS14865	COG0860	N-Acetylmuramoyl-L-alanine amidase
GIX96_RS14875	COG2207	Transcriptional regulator
GIX96_RS14880	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GIX96_RS14885	COG4816	utilization protein
GIX96_RS14895	COG4303	Ethanolamine ammonia lyase large subunit
GIX96_RS14900	COG4819	ethanolamine utilization protein
GIX96_RS14905	COG3192	ethanolamine utilization protein
GIX96_RS14910	COG1454	alcohol dehydrogenase
GIX96_RS14915	COG4820	ethanolamine utilization protein (EutJ)
GIX96_RS14920	COG1012	belongs to the aldehyde dehydrogenase family
GIX96_RS14925	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
GIX96_RS14930	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GIX96_RS14935	COG0280	phosphate acetyltransferase
GIX96_RS14940	COG4812	Cobalamin adenosyltransferase
GIX96_RS14945	COG4766	ethanolamine catabolic process
GIX96_RS14950	COG4917	ethanolamine utilization protein
GIX96_RS14955	COG4810	utilization protein
GIX96_RS14960	COG0280	phosphate acetyltransferase
GIX96_RS14960	COG0281	malic enzyme
GIX96_RS14965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GIX96_RS14970	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GIX96_RS14975	COG5342	invasion associated locus B
GIX96_RS14985	COG0493	'glutamate synthase
GIX96_RS14985	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS14990	COG3850	Histidine kinase
GIX96_RS14995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIX96_RS15005	COG1393	Belongs to the ArsC family
GIX96_RS15020	COG0400	carboxylic ester hydrolase activity
GIX96_RS15030	COG2321	neutral zinc metallopeptidase
GIX96_RS15040	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GIX96_RS15050	COG2716	regulation of RNA biosynthetic process
GIX96_RS15055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GIX96_RS15060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS15065	COG0651	ATP synthesis coupled electron transport
GIX96_RS15070	COG0650	Formate hydrogenlyase subunit 4
GIX96_RS15075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GIX96_RS15080	COG4237	Hydrogenase 4 membrane
GIX96_RS15085	COG0651	ATP synthesis coupled electron transport
GIX96_RS15090	COG3261	NADH dehydrogenase
GIX96_RS15090	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GIX96_RS15095	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GIX96_RS15100	COG3260	NADH ubiquinone oxidoreductase 20
GIX96_RS15110	COG3604	Transcriptional regulator
GIX96_RS15115	COG2116	formate transmembrane transporter activity
GIX96_RS15120	COG0628	permease
GIX96_RS15125	COG4783	chaperone-mediated protein folding
GIX96_RS15130	COG1393	Belongs to the ArsC family
GIX96_RS15140	COG2233	PERMEase
GIX96_RS15155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GIX96_RS15160	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GIX96_RS15165	COG0248	Ppx GppA phosphatase
GIX96_RS15170	COG2200	EAL domain
GIX96_RS15180	COG3133	Outer membrane lipoprotein
GIX96_RS15195	COG0516	GMP reductase activity
GIX96_RS15195	COG0517	IMP dehydrogenase activity
GIX96_RS15205	COG1645	bacterial-type flagellum-dependent swarming motility
GIX96_RS15220	COG2976	Protein conserved in bacteria
GIX96_RS15255	COG3302	dmso reductase anchor subunit
GIX96_RS15260	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS15265	COG0243	molybdopterin cofactor binding
GIX96_RS15270	COG4953	penicillin-binding protein 1C
GIX96_RS15275	COG2373	Large extracellular alpha-helical protein
GIX96_RS15280	COG2897	thiosulfate sulfurtransferase activity
GIX96_RS15295	COG2975	iron-sulfur cluster assembly
GIX96_RS15300	COG0633	Ferredoxin
GIX96_RS15320	COG0822	iron-sulfur transferase activity
GIX96_RS15340	COG0483	inositol monophosphate 1-phosphatase activity
GIX96_RS15345	COG1073	alpha beta
GIX96_RS15350	COG3711	transcriptional antiterminator
GIX96_RS15355	COG2814	Major facilitator Superfamily
GIX96_RS15360	COG0583	DNA-binding transcription factor activity
GIX96_RS15365	COG4638	Rieske (2fe-2S)
GIX96_RS15390	COG2259	Doxx family
GIX96_RS15395	COG2017	converts alpha-aldose to the beta-anomer
GIX96_RS15405	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS15410	COG1129	ABC transporter
GIX96_RS15415	COG1879	ABC-type sugar transport system periplasmic component
GIX96_RS15420	COG0457	Tetratricopeptide repeat
GIX96_RS15425	COG1940	carbohydrate kinase activity
GIX96_RS15435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GIX96_RS15435	COG1017	nitric oxide dioxygenase activity
GIX96_RS15440	COG0347	Belongs to the P(II) protein family
GIX96_RS15445	COG2204	response regulator
GIX96_RS15450	COG3170	Tfp pilus assembly protein FimV
GIX96_RS15455	COG2205	protein histidine kinase activity
GIX96_RS15460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GIX96_RS15460	COG0047	phosphoribosylformylglycinamidine synthase activity
GIX96_RS15465	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GIX96_RS15470	COG0590	tRNA wobble adenosine to inosine editing
GIX96_RS15475	COG0560	Phosphoserine phosphatase
GIX96_RS15480	COG1737	Transcriptional regulator
GIX96_RS15485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS15500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GIX96_RS15520	COG0681	Belongs to the peptidase S26 family
GIX96_RS15530	COG3086	response to oxidative stress
GIX96_RS15535	COG3026	antisigma factor binding
GIX96_RS15540	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GIX96_RS15545	COG1595	DNA-templated transcription, initiation
GIX96_RS15555	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GIX96_RS15560	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GIX96_RS15565	COG0513	Belongs to the DEAD box helicase family
GIX96_RS15570	COG0583	DNA-binding transcription factor activity
GIX96_RS15575	COG1280	lysine exporter protein (LysE YggA)
GIX96_RS15590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GIX96_RS15595	COG3118	belongs to the thioredoxin family
GIX96_RS15600	COG3148	PFAM DTW domain containing protein
GIX96_RS15605	COG0045	succinate-CoA ligase (ADP-forming) activity
GIX96_RS15605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GIX96_RS15605	COG1042	CoA-binding domain protein
GIX96_RS15610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GIX96_RS15615	COG5544	Lipoprotein
GIX96_RS15620	COG0477	Major facilitator Superfamily
GIX96_RS15645	COG0542	response to heat
GIX96_RS15655	COG0564	pseudouridine synthase activity
GIX96_RS15660	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GIX96_RS15665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GIX96_RS15675	COG0077	Prephenate dehydratase
GIX96_RS15675	COG1605	Chorismate mutase
GIX96_RS15680	COG1605	Chorismate mutase
GIX96_RS15680	COG0287	Prephenate dehydrogenase
GIX96_RS15685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GIX96_RS15700	COG2199	diguanylate cyclase activity
GIX96_RS15705	COG2885	chlorophyll binding
GIX96_RS15730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GIX96_RS15735	COG4137	Cytochrome C assembly protein
GIX96_RS15740	COG4536	flavin adenine dinucleotide binding
GIX96_RS15755	COG0497	DNA recombination
GIX96_RS15760	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GIX96_RS15770	COG2867	negative regulation of translational initiation
GIX96_RS15840	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS15900	COG2826	transposase and inactivated derivatives, IS30 family
GIX96_RS15950	COG3468	outer membrane autotransporter barrel domain protein
GIX96_RS15990	COG0579	oxidoreductase
GIX96_RS15995	COG1012	belongs to the aldehyde dehydrogenase family
GIX96_RS16000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GIX96_RS16005	COG1113	amino acid transport
GIX96_RS16010	COG1802	Transcriptional regulator
GIX96_RS16015	COG1652	LysM domain
GIX96_RS16020	COG0401	homolog of Blt101
GIX96_RS16025	COG0640	Transcriptional regulator
GIX96_RS16030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GIX96_RS16035	COG2916	Histone family protein nucleoid-structuring protein H-NS
GIX96_RS16050	COG4575	ribosome binding
GIX96_RS16060	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GIX96_RS16065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GIX96_RS16075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GIX96_RS16080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GIX96_RS16085	COG4175	Glycine betaine
GIX96_RS16090	COG4176	ABC-type proline glycine betaine transport system permease component
GIX96_RS16095	COG2113	Glycine betaine
GIX96_RS16100	COG2814	Major facilitator Superfamily
GIX96_RS16105	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GIX96_RS16115	COG1846	Transcriptional regulator
GIX96_RS16120	COG1566	PFAM secretion protein HlyD family protein
GIX96_RS16125	COG2814	Major facilitator Superfamily
GIX96_RS16140	COG1238	metal cluster binding
GIX96_RS16145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GIX96_RS16175	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GIX96_RS16180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GIX96_RS16195	COG1546	Belongs to the CinA family
GIX96_RS16200	COG2951	lytic endotransglycosylase activity
GIX96_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS16225	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS16230	COG1349	DNA-binding transcription factor activity
GIX96_RS16235	COG0517	IMP dehydrogenase activity
GIX96_RS16235	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GIX96_RS16245	COG1773	rubredoxin
GIX96_RS16245	COG0426	domain, Protein
GIX96_RS16255	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GIX96_RS16260	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS16265	COG1609	Transcriptional regulator
GIX96_RS16270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIX96_RS16270	COG1263	PTS System
GIX96_RS16275	COG2723	6-phospho-beta-galactosidase activity
GIX96_RS16280	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GIX96_RS16290	COG3260	NADH ubiquinone oxidoreductase 20
GIX96_RS16295	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GIX96_RS16300	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GIX96_RS16300	COG3261	NADH dehydrogenase
GIX96_RS16305	COG0650	Formate hydrogenlyase subunit 4
GIX96_RS16310	COG0651	ATP synthesis coupled electron transport
GIX96_RS16315	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS16325	COG0375	protein maturation
GIX96_RS16330	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GIX96_RS16335	COG0298	carbon dioxide binding
GIX96_RS16340	COG0409	Hydrogenase expression formation protein
GIX96_RS16345	COG0309	Hydrogenase expression formation protein (HypE)
GIX96_RS16350	COG3604	Transcriptional regulator
GIX96_RS16365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GIX96_RS16375	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GIX96_RS16380	COG0163	prenyltransferase activity
GIX96_RS16385	COG1846	Transcriptional regulator
GIX96_RS16390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GIX96_RS16395	COG1388	LysM domain
GIX96_RS16395	COG4942	peptidase
GIX96_RS16450	COG2234	aminopeptidase activity
GIX96_RS16455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIX96_RS16460	COG1518	maintenance of DNA repeat elements
GIX96_RS16475	COG1857	crispr-associated protein
GIX96_RS16490	COG1203	CRISPR-associated helicase, Cas3
GIX96_RS16510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GIX96_RS16515	COG0720	synthase
GIX96_RS16520	COG0644	oxidoreductase
GIX96_RS16525	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GIX96_RS16530	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GIX96_RS16540	COG2086	electron transfer activity
GIX96_RS16550	COG0277	FAD linked oxidase domain protein
GIX96_RS16555	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS16560	COG2223	nitrite transmembrane transporter activity
GIX96_RS16565	COG1070	Carbohydrate kinase
GIX96_RS16570	COG0602	queuosine metabolic process
GIX96_RS16580	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GIX96_RS16590	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GIX96_RS16605	COG3956	TIGRFAM MazG family protein
GIX96_RS16610	COG2337	Toxic component of a toxin-antitoxin (TA) module
GIX96_RS16615	COG2336	PFAM SpoVT AbrB
GIX96_RS16620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GIX96_RS16625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GIX96_RS16635	COG4948	Mandelate Racemase Muconate Lactonizing
GIX96_RS16640	COG4948	Mandelate Racemase Muconate Lactonizing
GIX96_RS16645	COG4948	Mandelate Racemase Muconate Lactonizing
GIX96_RS16650	COG2271	Major facilitator Superfamily
GIX96_RS16655	COG0716	FMN binding
GIX96_RS16660	COG0564	pseudouridine synthase activity
GIX96_RS16665	COG3098	single-species biofilm formation
GIX96_RS16680	COG1611	Belongs to the LOG family
GIX96_RS16685	COG0814	amino acid
GIX96_RS16690	COG1760	l-serine dehydratase
GIX96_RS16700	COG1454	alcohol dehydrogenase
GIX96_RS16705	COG0235	Class ii aldolase
GIX96_RS16710	COG0738	Major facilitator superfamily
GIX96_RS16720	COG1070	Carbohydrate kinase
GIX96_RS16730	COG1349	DNA-binding transcription factor activity
GIX96_RS16740	COG2363	Small membrane protein
GIX96_RS16745	COG0583	DNA-binding transcription factor activity
GIX96_RS16755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GIX96_RS16760	COG2166	iron-sulfur cluster assembly
GIX96_RS16765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GIX96_RS16770	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GIX96_RS16790	COG0860	N-Acetylmuramoyl-L-alanine amidase
GIX96_RS16795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GIX96_RS16795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GIX96_RS16800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GIX96_RS16805	COG1074	ATP-dependent DNA helicase activity
GIX96_RS16810	COG1025	Belongs to the peptidase M16 family
GIX96_RS16815	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GIX96_RS16820	COG4967	type IV pilus modification protein PilV
GIX96_RS16830	COG4795	General secretion pathway protein
GIX96_RS16835	COG2165	general secretion pathway protein
GIX96_RS16850	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GIX96_RS16865	COG0861	Integral membrane protein TerC family
GIX96_RS16875	COG0667	Aldo Keto reductase
GIX96_RS16890	COG1609	Transcriptional regulator
GIX96_RS16900	COG0583	DNA-binding transcription factor activity
GIX96_RS16905	COG1794	racemase activity, acting on amino acids and derivatives
GIX96_RS16910	COG2814	Major facilitator Superfamily
GIX96_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS16925	COG0183	Belongs to the thiolase family
GIX96_RS16930	COG0814	amino acid
GIX96_RS16935	COG2771	luxR family
GIX96_RS16940	COG3710	Transcriptional regulator
GIX96_RS16965	COG0457	Tetratricopeptide repeat
GIX96_RS16970	COG0457	Tetratricopeptide repeat
GIX96_RS16970	COG3710	Transcriptional regulator
GIX96_RS16980	COG0741	lytic transglycosylase activity
GIX96_RS16985	COG2197	response regulator
GIX96_RS17095	COG2207	Transcriptional regulator
GIX96_RS17115	COG4942	peptidase
GIX96_RS17120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GIX96_RS17125	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GIX96_RS17130	COG2080	2 iron, 2 sulfur cluster binding
GIX96_RS17135	COG3829	transcription factor binding
GIX96_RS17140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GIX96_RS17145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GIX96_RS17150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GIX96_RS17160	COG0549	Belongs to the carbamate kinase family
GIX96_RS17165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GIX96_RS17165	COG3608	succinylglutamate desuccinylase aspartoacylase
GIX96_RS17170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GIX96_RS17175	COG2068	MobA-Related Protein
GIX96_RS17180	COG0493	'glutamate synthase
GIX96_RS17180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS17185	COG0402	S-adenosylhomocysteine deaminase activity
GIX96_RS17190	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GIX96_RS17195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GIX96_RS17195	COG2080	2 iron, 2 sulfur cluster binding
GIX96_RS17200	COG2233	PERMEase
GIX96_RS17205	COG0402	S-adenosylhomocysteine deaminase activity
GIX96_RS17210	COG2252	PERMEase
GIX96_RS17220	COG0493	'glutamate synthase
GIX96_RS17220	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS17225	COG2233	PERMEase
GIX96_RS17245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GIX96_RS17255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GIX96_RS17260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GIX96_RS17265	COG4974	Belongs to the 'phage' integrase family
GIX96_RS17270	COG0716	FMN binding
GIX96_RS17280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GIX96_RS17290	COG1272	protein, Hemolysin III
GIX96_RS17300	COG2723	6-phospho-beta-galactosidase activity
GIX96_RS17325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GIX96_RS17330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GIX96_RS17335	COG0006	proline dipeptidase activity
GIX96_RS17355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GIX96_RS17370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GIX96_RS17385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GIX96_RS17385	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GIX96_RS17390	COG1703	isobutyryl-CoA mutase activity
GIX96_RS17395	COG1024	Enoyl-CoA hydratase
GIX96_RS17400	COG0427	acetyl-CoA hydrolase
GIX96_RS17405	COG0583	DNA-binding transcription factor activity
GIX96_RS17410	COG0583	DNA-binding transcription factor activity
GIX96_RS17415	COG2968	Membrane
GIX96_RS17425	COG0668	transmembrane transport
GIX96_RS17430	COG0191	fructose-bisphosphate aldolase activity
GIX96_RS17435	COG0126	phosphoglycerate kinase activity
GIX96_RS17460	COG1122	ATPase activity
GIX96_RS17465	COG1122	ATPase activity
GIX96_RS17470	COG1072	(Pantothenic acid kinase))
GIX96_RS17480	COG1494	fructose-1,6-bisphosphatase
GIX96_RS17485	COG1063	alcohol dehydrogenase
GIX96_RS17490	COG2213	PTS system mannitol-specific
GIX96_RS17495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS17500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GIX96_RS17505	COG0501	Belongs to the peptidase M48B family
GIX96_RS17520	COG1166	arginine decarboxylase activity
GIX96_RS17535	COG2814	Major facilitator Superfamily
GIX96_RS17540	COG3091	SprT-like family
GIX96_RS17545	COG2356	endonuclease I
GIX96_RS17550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GIX96_RS17555	COG0189	ligase activity
GIX96_RS17570	COG2805	Type II/IV secretion system protein
GIX96_RS17575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GIX96_RS17580	COG0762	integral membrane protein
GIX96_RS17590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GIX96_RS17595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GIX96_RS17605	COG0252	asparaginase activity
GIX96_RS17615	COG3171	Protein conserved in bacteria
GIX96_RS17625	COG1194	a g-specific adenine glycosylase
GIX96_RS17640	COG2211	Major facilitator Superfamily
GIX96_RS17645	COG1982	Orn Lys Arg decarboxylase major
GIX96_RS17650	COG1811	Na channel or pump
GIX96_RS17660	COG0582	viral genome integration into host DNA
GIX96_RS17675	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS17740	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS17745	COG4372	Transposase
GIX96_RS17750	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS17775	COG0754	glutathionylspermidine amidase activity
GIX96_RS17780	COG0625	glutathione transferase activity
GIX96_RS17785	COG0298	carbon dioxide binding
GIX96_RS17790	COG0375	protein maturation
GIX96_RS17795	COG1773	rubredoxin
GIX96_RS17800	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GIX96_RS17805	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GIX96_RS17810	COG5557	Pfam Polysulphide reductase, NrfD
GIX96_RS17815	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS17820	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GIX96_RS17835	COG0667	Aldo Keto reductase
GIX96_RS17845	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS17850	COG0848	biopolymer transport protein
GIX96_RS17855	COG0811	peptide transport
GIX96_RS17860	COG0626	cystathionine gamma-synthase activity
GIX96_RS17865	COG0586	Pfam SNARE associated Golgi protein
GIX96_RS17870	COG2207	Transcriptional regulator
GIX96_RS17875	COG1979	alcohol dehydrogenase
GIX96_RS17880	COG0656	L-ascorbic acid biosynthetic process
GIX96_RS17890	COG4238	major outer membrane lipoprotein
GIX96_RS17895	COG1032	radical SAM domain protein
GIX96_RS17900	COG2132	Multicopper oxidase
GIX96_RS17905	COG0204	Acyl-transferase
GIX96_RS17910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GIX96_RS17915	COG4166	transmembrane transport
GIX96_RS17920	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GIX96_RS17925	COG3111	PFAM Bacterial OB fold (BOF) protein
GIX96_RS17930	COG0745	RESPONSE REGULATOR receiver
GIX96_RS17935	COG0642	Histidine kinase
GIX96_RS17940	COG2249	NAD(P)H dehydrogenase (quinone) activity
GIX96_RS17945	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GIX96_RS17950	COG1737	Transcriptional regulator
GIX96_RS17960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIX96_RS17965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIX96_RS17970	COG1120	ATPase activity
GIX96_RS17975	COG4774	siderophore transport
GIX96_RS17980	COG0187	DNA topoisomerase II activity
GIX96_RS17985	COG3150	esterase
GIX96_RS17990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GIX96_RS17995	COG3151	Protein conserved in bacteria
GIX96_RS18000	COG0494	nUDIX hydrolase
GIX96_RS18005	COG1538	Outer membrane efflux protein
GIX96_RS18015	COG0754	glutathionylspermidine amidase activity
GIX96_RS18020	COG3384	dioxygenase
GIX96_RS18050	COG1585	Membrane protein implicated in regulation of membrane protease activity
GIX96_RS18080	COG3025	triphosphatase activity
GIX96_RS18085	COG4991	sh3 domain protein
GIX96_RS18100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GIX96_RS18110	COG0583	DNA-binding transcription factor activity
GIX96_RS18115	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GIX96_RS18120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GIX96_RS18125	COG0471	metal ion transport
GIX96_RS18130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GIX96_RS18135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GIX96_RS18140	COG0358	DNA primase activity
GIX96_RS18145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GIX96_RS18160	COG2375	cellular response to nickel ion
GIX96_RS18165	COG1695	Transcriptional regulator
GIX96_RS18170	COG0840	transmembrane signaling receptor activity
GIX96_RS18180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GIX96_RS18185	COG1609	Transcriptional regulator
GIX96_RS18190	COG3250	beta-galactosidase activity
GIX96_RS18195	COG2731	YhcH YjgK YiaL family protein
GIX96_RS18200	COG0531	amino acid
GIX96_RS18210	COG3408	Glycogen debranching enzyme
GIX96_RS18210	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GIX96_RS18215	COG1902	pentaerythritol trinitrate reductase activity
GIX96_RS18215	COG0446	pyridine nucleotide-disulphide oxidoreductase
GIX96_RS18220	COG5499	transcription regulator containing HTH domain
GIX96_RS18225	COG4680	protein conserved in bacteria
GIX96_RS18235	COG1451	nucleotide metabolic process
GIX96_RS18240	COG2949	membrane
GIX96_RS18245	COG0673	inositol 2-dehydrogenase activity
GIX96_RS18250	COG0861	Integral membrane protein TerC family
GIX96_RS18255	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GIX96_RS18265	COG2721	sulfolactate sulfo-lyase activity
GIX96_RS18275	COG2271	Major facilitator Superfamily
GIX96_RS18280	COG2186	Transcriptional regulator
GIX96_RS18285	COG0586	Pfam SNARE associated Golgi protein
GIX96_RS18295	COG1422	Protein of unknown function (DUF1090)
GIX96_RS18300	COG4575	ribosome binding
GIX96_RS18305	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GIX96_RS18315	COG2259	Doxx family
GIX96_RS18320	COG0435	Glutathione S-transferase
GIX96_RS18325	COG3152	Membrane
GIX96_RS18330	COG3152	Membrane
GIX96_RS18335	COG0583	DNA-binding transcription factor activity
GIX96_RS18340	COG1741	Belongs to the pirin family
GIX96_RS18355	COG0814	amino acid
GIX96_RS18360	COG1760	l-serine dehydratase
GIX96_RS18365	COG0251	oxidation-reduction process
GIX96_RS18370	COG1882	Formate acetyltransferase
GIX96_RS18375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GIX96_RS18385	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GIX96_RS18390	COG0583	DNA-binding transcription factor activity
GIX96_RS18415	COG1929	Belongs to the glycerate kinase type-1 family
GIX96_RS18420	COG2084	Dehydrogenase
GIX96_RS18430	COG2271	Major facilitator Superfamily
GIX96_RS18435	COG2721	sulfolactate sulfo-lyase activity
GIX96_RS18440	COG2002	toxin-antitoxin pair type II binding
GIX96_RS18450	COG1349	DNA-binding transcription factor activity
GIX96_RS18460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIX96_RS18470	COG3716	PTS system mannose fructose sorbose family IID component
GIX96_RS18475	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS18480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GIX96_RS18485	COG2222	sugar isomerase
GIX96_RS18495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIX96_RS18505	COG3716	PTS system mannose fructose sorbose family IID component
GIX96_RS18515	COG3539	Fimbrial protein
GIX96_RS18520	COG3121	Chaperone
GIX96_RS18525	COG3188	usher protein
GIX96_RS18530	COG3539	Fimbrial protein
GIX96_RS18540	COG3539	Fimbrial protein
GIX96_RS18545	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GIX96_RS18565	COG2823	Periplasmic or secreted lipoprotein
GIX96_RS18570	COG0701	Predicted permease
GIX96_RS18575	COG0702	epimerase
GIX96_RS18580	COG0693	protein deglycase activity
GIX96_RS18585	COG3787	Belongs to the UPF0306 family
GIX96_RS18595	COG3153	acetyltransferase
GIX96_RS18600	COG3154	lipid carrier protein
GIX96_RS18605	COG0826	peptidase U32
GIX96_RS18610	COG0826	peptidase U32
GIX96_RS18615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GIX96_RS18620	COG0814	amino acid
GIX96_RS18625	COG0513	Belongs to the DEAD box helicase family
GIX96_RS18665	COG0195	Participates in both transcription termination and antitermination
GIX96_RS18685	COG2194	sulfuric ester hydrolase activity
GIX96_RS18695	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GIX96_RS18705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GIX96_RS18710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GIX96_RS18720	COG1534	Rna-binding protein
GIX96_RS18725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GIX96_RS18730	COG2027	D-alanyl-D-alanine carboxypeptidase
GIX96_RS18740	COG0697	spore germination
GIX96_RS18755	COG0142	geranyltranstransferase activity
GIX96_RS18760	COG3423	Transcriptional regulator
GIX96_RS18770	COG5007	Belongs to the BolA IbaG family
GIX96_RS18775	COG3113	response to antibiotic
GIX96_RS18780	COG2854	intermembrane phospholipid transfer
GIX96_RS18785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GIX96_RS18790	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GIX96_RS18795	COG1127	ABC transporter
GIX96_RS18800	COG0530	calcium, potassium:sodium antiporter activity
GIX96_RS18805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GIX96_RS18805	COG0517	IMP dehydrogenase activity
GIX96_RS18810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GIX96_RS18815	COG3117	lipopolysaccharide transmembrane transporter activity
GIX96_RS18820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GIX96_RS18825	COG1137	ATPase activity
GIX96_RS18830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GIX96_RS18835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GIX96_RS18850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS18855	COG0515	serine threonine protein kinase
GIX96_RS18865	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GIX96_RS18870	COG0784	Response regulator, receiver
GIX96_RS18870	COG2198	Histidine kinase
GIX96_RS18870	COG5002	protein histidine kinase activity
GIX96_RS18875	COG1242	4 iron, 4 sulfur cluster binding
GIX96_RS18880	COG0067	glutamate synthase
GIX96_RS18880	COG0069	glutamate synthase activity
GIX96_RS18880	COG0070	glutamate synthase
GIX96_RS18885	COG0493	'glutamate synthase
GIX96_RS18890	COG4804	nuclease activity
GIX96_RS18895	COG2731	YhcH YjgK YiaL family protein
GIX96_RS18925	COG3069	C4-dicarboxylate transmembrane transporter activity
GIX96_RS18930	COG2969	positive regulation of protein catabolic process
GIX96_RS18935	COG0625	glutathione transferase activity
GIX96_RS18950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GIX96_RS18955	COG3105	Protein conserved in bacteria
GIX96_RS18960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GIX96_RS18965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GIX96_RS18985	COG2732	(Barnase) inhibitor
GIX96_RS19005	COG0583	DNA-binding transcription factor activity
GIX96_RS19010	COG0312	modulator of DNA gyrase
GIX96_RS19015	COG3164	Protein of unknown function
GIX96_RS19020	COG1530	ribonuclease E activity
GIX96_RS19025	COG0424	maF-like protein
GIX96_RS19030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GIX96_RS19035	COG1792	Involved in formation and maintenance of cell shape
GIX96_RS19040	COG1077	Cell shape determining protein MreB Mrl
GIX96_RS19045	COG2200	EAL domain
GIX96_RS19045	COG2199	diguanylate cyclase activity
GIX96_RS19050	COG0604	alcohol dehydrogenase
GIX96_RS19055	COG0511	ligase activity, forming carbon-carbon bonds
GIX96_RS19060	COG0439	Biotin carboxylase
GIX96_RS19065	COG3924	membrane
GIX96_RS19070	COG4145	pantothenate transmembrane transporter activity
GIX96_RS19080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GIX96_RS19090	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GIX96_RS19100	COG1309	transcriptional regulator
GIX96_RS19105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIX96_RS19120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIX96_RS19125	COG4597	amino acid ABC transporter
GIX96_RS19130	COG0765	amino acid transport
GIX96_RS19135	COG1126	abc transporter atp-binding protein
GIX96_RS19175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GIX96_RS19190	COG0009	L-threonylcarbamoyladenylate synthase
GIX96_RS19195	COG0551	DNA topoisomerase type I activity
GIX96_RS19205	COG0758	DNA mediated transformation
GIX96_RS19225	COG0569	domain protein
GIX96_RS19235	COG3036	rescue of stalled ribosome
GIX96_RS19240	COG0789	Transcriptional regulator
GIX96_RS19280	COG0201	protein transport
GIX96_RS19370	COG0089	rRNA binding
GIX96_RS19440	COG2964	Protein conserved in bacteria
GIX96_RS19445	COG0545	Peptidyl-prolyl cis-trans isomerase
GIX96_RS19455	COG1047	Peptidyl-prolyl cis-trans
GIX96_RS19460	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GIX96_RS19475	COG0488	(ABC) transporter
GIX96_RS19480	COG0429	hydrolase of the alpha beta-hydrolase fold
GIX96_RS19490	COG3954	Phosphoribulokinase
GIX96_RS19495	COG1765	OsmC-like protein
GIX96_RS19500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GIX96_RS19505	COG1289	transmembrane transporter activity
GIX96_RS19510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GIX96_RS19515	COG0512	Glutamine amidotransferase of anthranilate synthase
GIX96_RS19520	COG2184	nucleotidyltransferase activity
GIX96_RS19530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GIX96_RS19540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GIX96_RS19545	COG2146	nitrite reductase [NAD(P)H] activity
GIX96_RS19550	COG2116	formate transmembrane transporter activity
GIX96_RS19565	COG0531	amino acid
GIX96_RS19570	COG2222	sugar isomerase
GIX96_RS19575	COG1082	Xylose isomerase domain protein TIM barrel
GIX96_RS19580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS19585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS19590	COG2188	Transcriptional regulator
GIX96_RS19595	COG0180	Tryptophanyl-tRNA synthetase
GIX96_RS19600	COG0546	phosphoglycolate phosphatase activity
GIX96_RS19605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GIX96_RS19610	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GIX96_RS19615	COG3266	domain, Protein
GIX96_RS19630	COG4796	Type ii and iii secretion system protein
GIX96_RS19645	COG3166	PFAM Fimbrial assembly family protein
GIX96_RS19650	COG4972	Pilus assembly protein
GIX96_RS19655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GIX96_RS19660	COG0494	nUDIX hydrolase
GIX96_RS19670	COG1011	Hydrolase
GIX96_RS19675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GIX96_RS19685	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GIX96_RS19705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GIX96_RS19710	COG2183	response to ionizing radiation
GIX96_RS19715	COG1918	ferrous iron import across plasma membrane
GIX96_RS19720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GIX96_RS19730	COG5464	transposase or invertase
GIX96_RS19740	COG1040	competence protein
GIX96_RS19750	COG2610	gluconate transmembrane transporter activity
GIX96_RS19755	COG1640	4-alpha-glucanotransferase
GIX96_RS19760	COG0058	SHG alpha-glucan phosphorylase activity
GIX96_RS19785	COG1690	Belongs to the RtcB family
GIX96_RS19790	COG4650	regulator
GIX96_RS19795	COG1349	DNA-binding transcription factor activity
GIX96_RS19810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GIX96_RS19825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GIX96_RS19830	COG0058	SHG alpha-glucan phosphorylase activity
GIX96_RS19850	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GIX96_RS19855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GIX96_RS19860	COG2095	MarC family integral membrane protein
GIX96_RS19880	COG0514	ATP-dependent DNA helicase (RecQ)
GIX96_RS19885	COG2610	gluconate transmembrane transporter activity
GIX96_RS19890	COG3265	gluconokinase activity
GIX96_RS19895	COG1609	Transcriptional regulator
GIX96_RS19905	COG1741	Belongs to the pirin family
GIX96_RS19910	COG0673	inositol 2-dehydrogenase activity
GIX96_RS19915	COG1247	-acetyltransferase
GIX96_RS19925	COG0405	Gamma-glutamyltransferase
GIX96_RS19935	COG0584	glycerophosphoryl diester phosphodiesterase
GIX96_RS19940	COG3842	ATPase activity
GIX96_RS19950	COG1175	transmembrane transport
GIX96_RS19955	COG1653	transport
GIX96_RS19965	COG0410	ABC transporter
GIX96_RS19970	COG0411	ABC transporter
GIX96_RS19975	COG4177	L-phenylalanine transmembrane transporter activity
GIX96_RS19980	COG0559	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS19985	COG0683	leucine binding
GIX96_RS19990	COG0456	acetyltransferase
GIX96_RS20005	COG0683	leucine binding
GIX96_RS20010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GIX96_RS20015	COG2177	Part of the ABC transporter FtsEX involved in
GIX96_RS20020	COG2884	Cell division ATP-binding protein ftsE
GIX96_RS20025	COG0552	protein localization to endoplasmic reticulum
GIX96_RS20030	COG0742	ribosomal rna small subunit methyltransferase
GIX96_RS20035	COG3776	membrane
GIX96_RS20045	COG3714	YhhN family
GIX96_RS20060	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GIX96_RS20070	COG0477	Major facilitator Superfamily
GIX96_RS20075	COG0628	permease
GIX96_RS20105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GIX96_RS20125	COG1216	Glycosyl transferase, family 2
GIX96_RS20150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIX96_RS20160	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS20165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIX96_RS20170	COG2091	lysine biosynthetic process via aminoadipic acid
GIX96_RS20175	COG0747	negative chemotaxis
GIX96_RS20180	COG0601	transmembrane transport
GIX96_RS20185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIX96_RS20190	COG0444	Belongs to the ABC transporter superfamily
GIX96_RS20195	COG1124	(ABC) transporter
GIX96_RS20205	COG2188	Transcriptional regulator
GIX96_RS20215	COG3414	Phosphotransferase system galactitol-specific IIB component
GIX96_RS20220	COG3775	system Galactitol-specific IIC component
GIX96_RS20235	COG0191	fructose-bisphosphate aldolase activity
GIX96_RS20250	COG0842	Transport permease protein
GIX96_RS20255	COG1129	ABC transporter
GIX96_RS20255	COG0842	Transport permease protein
GIX96_RS20260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIX96_RS20280	COG2081	HI0933 family
GIX96_RS20285	COG0306	phosphate transporter
GIX96_RS20295	COG0589	response to stress
GIX96_RS20300	COG3104	oligopeptide transport
GIX96_RS20310	COG0339	signal peptide processing
GIX96_RS20315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GIX96_RS20320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GIX96_RS20330	COG0640	Transcriptional regulator
GIX96_RS20335	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GIX96_RS20340	COG1393	Belongs to the ArsC family
GIX96_RS20350	COG3065	identical protein binding
GIX96_RS20355	COG2197	response regulator
GIX96_RS20360	COG3720	iron ion transport
GIX96_RS20365	COG4771	TonB-dependent receptor
GIX96_RS20375	COG4558	Periplasmic binding protein
GIX96_RS20385	COG3721	Heme iron utilization protein
GIX96_RS20395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIX96_RS20400	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GIX96_RS20405	COG1285	pathogenesis
GIX96_RS20415	COG0076	glutamate decarboxylase activity
GIX96_RS20420	COG1858	cytochrome C peroxidase
GIX96_RS20430	COG2197	response regulator
GIX96_RS20435	COG0583	DNA-binding transcription factor activity
GIX96_RS20440	COG1295	ribonuclease BN
GIX96_RS20445	COG0477	Major facilitator Superfamily
GIX96_RS20450	COG2982	Protein involved in outer membrane biogenesis
GIX96_RS20455	COG2200	EAL domain
GIX96_RS20465	COG0612	Peptidase, M16
GIX96_RS20475	COG2199	diguanylate cyclase activity
GIX96_RS20475	COG2200	EAL domain
GIX96_RS20485	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GIX96_RS20490	COG1215	transferase activity, transferring glycosyl groups
GIX96_RS20495	COG1215	transferase activity, transferring glycosyl groups
GIX96_RS20520	COG2194	sulfuric ester hydrolase activity
GIX96_RS20530	COG0814	amino acid
GIX96_RS20535	COG4608	Belongs to the ABC transporter superfamily
GIX96_RS20540	COG0444	Belongs to the ABC transporter superfamily
GIX96_RS20545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIX96_RS20550	COG0601	transmembrane transport
GIX96_RS20555	COG0747	negative chemotaxis
GIX96_RS20565	COG2194	sulfuric ester hydrolase activity
GIX96_RS20570	COG3539	Fimbrial protein
GIX96_RS20575	COG3539	Fimbrial protein
GIX96_RS20585	COG3121	Chaperone
GIX96_RS20590	COG3539	Fimbrial protein
GIX96_RS20595	COG2223	nitrite transmembrane transporter activity
GIX96_RS20600	COG5571	outer membrane autotransporter
GIX96_RS20605	COG2818	Glycosylase
GIX96_RS20610	COG0456	acetyltransferase
GIX96_RS20615	COG0243	molybdopterin cofactor binding
GIX96_RS20620	COG2885	chlorophyll binding
GIX96_RS20635	COG2944	sequence-specific DNA binding
GIX96_RS20640	COG1278	Cold shock
GIX96_RS20665	COG3274	enterobacterial common antigen metabolic process
GIX96_RS20670	COG4682	membrane
GIX96_RS20675	COG4682	membrane
GIX96_RS20680	COG1070	Carbohydrate kinase
GIX96_RS20690	COG4213	ABC transporter substrate-binding protein
GIX96_RS20700	COG4214	carbohydrate transport
GIX96_RS20705	COG2207	Transcriptional regulator
GIX96_RS20705	COG1609	Transcriptional regulator
GIX96_RS20710	COG2992	FlgJ-related protein
GIX96_RS20715	COG0366	Alpha amylase catalytic
GIX96_RS20720	COG3977	Valine--pyruvate aminotransferase
GIX96_RS20725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIX96_RS20730	COG1414	Transcriptional regulator
GIX96_RS20740	COG2211	Major facilitator Superfamily
GIX96_RS20750	COG3713	MltA-interacting MipA family protein
GIX96_RS20755	COG0583	DNA-binding transcription factor activity
GIX96_RS20760	COG1566	PFAM secretion protein HlyD family protein
GIX96_RS20770	COG1012	belongs to the aldehyde dehydrogenase family
GIX96_RS20780	COG1454	alcohol dehydrogenase
GIX96_RS20785	COG3276	selenocysteine insertion sequence binding
GIX96_RS20795	COG0625	glutathione transferase activity
GIX96_RS20800	COG3209	COG3209 Rhs family protein
GIX96_RS20805	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GIX96_RS20815	COG1566	PFAM secretion protein HlyD family protein
GIX96_RS20825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS20825	COG2213	PTS system mannitol-specific
GIX96_RS20835	COG3722	fumarate hydratase activity
GIX96_RS20855	COG5295	Hep Hag repeat protein
GIX96_RS20860	COG1620	l-lactate permease
GIX96_RS20865	COG2186	Transcriptional regulator
GIX96_RS20875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GIX96_RS20880	COG1045	serine acetyltransferase
GIX96_RS20895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GIX96_RS20900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GIX96_RS20910	COG4942	peptidase
GIX96_RS20915	COG2861	carbohydrate metabolic process
GIX96_RS20920	COG1216	Glycosyl transferase, family 2
GIX96_RS20930	COG0156	8-amino-7-oxononanoate synthase activity
GIX96_RS20945	COG0859	PFAM glycosyl transferase family 9
GIX96_RS20950	COG0859	PFAM glycosyl transferase family 9
GIX96_RS20970	COG3642	lipopolysaccharide core region biosynthetic process
GIX96_RS20980	COG0515	serine threonine protein kinase
GIX96_RS20985	COG0438	transferase activity, transferring glycosyl groups
GIX96_RS20990	COG0859	PFAM glycosyl transferase family 9
GIX96_RS20995	COG1519	Transferase
GIX96_RS21025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GIX96_RS21050	COG1561	YicC-like family, N-terminal region
GIX96_RS21055	COG3645	SOS response
GIX96_RS21060	COG2860	membrane
GIX96_RS21070	COG0194	GDP metabolic process
GIX96_RS21080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GIX96_RS21085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GIX96_RS21090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GIX96_RS21100	COG0786	glutamate:sodium symporter activity
GIX96_RS21105	COG2233	PERMEase
GIX96_RS21110	COG2982	Protein involved in outer membrane biogenesis
GIX96_RS21115	COG1501	Belongs to the glycosyl hydrolase 31 family
GIX96_RS21120	COG2211	Major facilitator Superfamily
GIX96_RS21130	COG0582	viral genome integration into host DNA
GIX96_RS21170	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS21175	COG4372	Transposase
GIX96_RS21230	COG5492	domain, Protein
GIX96_RS21400	COG0697	spore germination
GIX96_RS21405	COG1464	Belongs to the NlpA lipoprotein family
GIX96_RS21415	COG2814	Major facilitator Superfamily
GIX96_RS21445	COG2271	Major facilitator Superfamily
GIX96_RS21450	COG2271	Major facilitator Superfamily
GIX96_RS21455	COG3851	Histidine kinase
GIX96_RS21460	COG2197	response regulator
GIX96_RS21480	COG0440	acetolactate synthase activity
GIX96_RS21485	COG0028	Belongs to the TPP enzyme family
GIX96_RS21500	COG2814	Major facilitator Superfamily
GIX96_RS21505	COG0641	radical SAM
GIX96_RS21515	COG2149	membrane
GIX96_RS21525	COG3119	arylsulfatase activity
GIX96_RS21530	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GIX96_RS21535	COG2207	Transcriptional regulator
GIX96_RS21550	COG2188	Transcriptional regulator
GIX96_RS21570	COG5645	(Lipo)protein
GIX96_RS21575	COG0823	Involved in the tonB-independent uptake of proteins
GIX96_RS21580	COG0644	oxidoreductase
GIX96_RS21590	COG0561	phosphatase activity
GIX96_RS21595	COG3753	Protein conserved in bacteria
GIX96_RS21600	COG0187	DNA topoisomerase II activity
GIX96_RS21610	COG0592	DNA-directed DNA polymerase activity
GIX96_RS21665	COG0814	amino acid
GIX96_RS21680	COG2091	lysine biosynthetic process via aminoadipic acid
GIX96_RS21685	COG0431	NADPH-dependent FMN reductase
GIX96_RS21690	COG2252	PERMEase
GIX96_RS21695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GIX96_RS21720	COG0704	Plays a role in the regulation of phosphate uptake
GIX96_RS21725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GIX96_RS21730	COG0581	inorganic phosphate transmembrane transporter activity
GIX96_RS21735	COG0573	inorganic phosphate transmembrane transporter activity
GIX96_RS21740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GIX96_RS21750	COG3539	Fimbrial protein
GIX96_RS21775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GIX96_RS21785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GIX96_RS21825	COG3312	ion transport
GIX96_RS21840	COG0716	FMN binding
GIX96_RS21845	COG1522	sequence-specific DNA binding
GIX96_RS21865	COG3158	transport of potassium into the cell
GIX96_RS21875	COG1129	ABC transporter
GIX96_RS21880	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS21885	COG1879	ABC-type sugar transport system periplasmic component
GIX96_RS21890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS21895	COG1609	Transcriptional regulator
GIX96_RS21900	COG0477	Major facilitator Superfamily
GIX96_RS21905	COG2186	Transcriptional regulator
GIX96_RS21945	COG3085	chromosome segregation
GIX96_RS21950	COG0606	chelatase, subunit chli
GIX96_RS21970	COG3978	acetolactate synthase activity
GIX96_RS21975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GIX96_RS21985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GIX96_RS21990	COG0583	DNA-binding transcription factor activity
GIX96_RS22000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GIX96_RS22005	COG3692	DNA binding
GIX96_RS22010	COG0210	DNA helicase
GIX96_RS22020	COG0513	Belongs to the DEAD box helicase family
GIX96_RS22025	COG3118	belongs to the thioredoxin family
GIX96_RS22035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GIX96_RS22040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GIX96_RS22045	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GIX96_RS22050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GIX96_RS22055	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GIX96_RS22060	COG1088	dTDP-glucose 4,6-dehydratase activity
GIX96_RS22065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GIX96_RS22070	COG0456	acetyltransferase
GIX96_RS22075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GIX96_RS22080	COG2244	polysaccharide biosynthetic process
GIX96_RS22085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GIX96_RS22100	COG1113	amino acid transport
GIX96_RS22130	COG0641	radical SAM
GIX96_RS22135	COG3119	arylsulfatase activity
GIX96_RS22140	COG3071	HemY protein
GIX96_RS22145	COG2959	enzyme of heme biosynthesis
GIX96_RS22150	COG1587	Uroporphyrinogen-III synthase
GIX96_RS22160	COG3072	Adenylate cyclase
GIX96_RS22170	COG5567	small periplasmic lipoprotein
GIX96_RS22180	COG3159	Protein conserved in bacteria
GIX96_RS22190	COG1011	Hydrolase
GIX96_RS22195	COG0210	DNA helicase
GIX96_RS22200	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
GIX96_RS22205	COG3698	Phosphodiester glycosidase
GIX96_RS22210	COG0598	Magnesium transport protein CorA
GIX96_RS22235	COG2962	Rard protein
GIX96_RS22240	COG2050	protein possibly involved in aromatic compounds catabolism
GIX96_RS22245	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GIX96_RS22250	COG0514	ATP-dependent DNA helicase (RecQ)
GIX96_RS22255	COG1280	lysine exporter protein (LysE YggA)
GIX96_RS22260	COG1280	lysine exporter protein (LysE YggA)
GIX96_RS22265	COG2267	carboxylic ester hydrolase activity
GIX96_RS22270	COG0561	phosphatase activity
GIX96_RS22275	COG0697	spore germination
GIX96_RS22280	COG0583	DNA-binding transcription factor activity
GIX96_RS22285	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GIX96_RS22290	COG0412	Dienelactone hydrolase
GIX96_RS22295	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GIX96_RS22300	COG1322	Protein conserved in bacteria
GIX96_RS22310	COG3165	ubiquinone biosynthetic process from chorismate
GIX96_RS22320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GIX96_RS22325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GIX96_RS22330	COG0805	protein transport
GIX96_RS22335	COG0084	hydrolase, TatD family'
GIX96_RS22340	COG0250	Participates in transcription elongation, termination and antitermination
GIX96_RS22345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GIX96_RS22350	COG0543	2 iron, 2 sulfur cluster binding
GIX96_RS22355	COG0183	Belongs to the thiolase family
GIX96_RS22370	COG1739	Uncharacterized protein family UPF0029
GIX96_RS22375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GIX96_RS22380	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GIX96_RS22410	COG1763	Mo-molybdopterin cofactor biosynthetic process
GIX96_RS22415	COG0746	molybdenum cofactor guanylyltransferase activity
GIX96_RS22420	COG3084	Protein conserved in bacteria
GIX96_RS22425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GIX96_RS22430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GIX96_RS22435	COG5339	Protein conserved in bacteria
GIX96_RS22440	COG0204	Acyl-transferase
GIX96_RS22450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GIX96_RS22450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GIX96_RS22460	COG3078	GTPase activator activity
GIX96_RS22465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GIX96_RS22475	COG2204	response regulator
GIX96_RS22480	COG3852	Histidine kinase
GIX96_RS22485	COG0174	glutamine synthetase
GIX96_RS22490	COG1217	gtp-binding protein TYPA
GIX96_RS22495	COG2188	Transcriptional regulator
GIX96_RS22500	COG1082	Xylose isomerase domain protein TIM barrel
GIX96_RS22505	COG2271	Major facilitator Superfamily
GIX96_RS22510	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GIX96_RS22515	COG2211	Major facilitator Superfamily
GIX96_RS22520	COG2211	Major facilitator Superfamily
GIX96_RS22525	COG1501	Belongs to the glycosyl hydrolase 31 family
GIX96_RS22535	COG2017	converts alpha-aldose to the beta-anomer
GIX96_RS22540	COG2942	2-epimerase
GIX96_RS22545	COG3684	Belongs to the aldolase LacD family
GIX96_RS22550	COG2084	Dehydrogenase
GIX96_RS22555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS22560	COG1349	DNA-binding transcription factor activity
GIX96_RS22565	COG1011	Hydrolase
GIX96_RS22580	COG0456	acetyltransferase
GIX96_RS22595	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GIX96_RS22600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GIX96_RS22610	COG2864	formate dehydrogenase
GIX96_RS22615	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS22635	COG3711	transcriptional antiterminator
GIX96_RS22635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS22640	COG1363	Peptidase, m42
GIX96_RS22645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIX96_RS22645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIX96_RS22650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS22685	COG4977	sequence-specific DNA binding
GIX96_RS22685	COG1917	Cupin 2, conserved barrel domain protein
GIX96_RS22695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GIX96_RS22705	COG2258	MOSC domain
GIX96_RS22710	COG2205	protein histidine kinase activity
GIX96_RS22715	COG0745	RESPONSE REGULATOR receiver
GIX96_RS22720	COG3678	ATP-independent chaperone mediated protein folding
GIX96_RS22735	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GIX96_RS22755	COG3152	Membrane
GIX96_RS22760	COG3691	Protein conserved in bacteria
GIX96_RS22765	COG0589	response to stress
GIX96_RS22775	COG1494	fructose-1,6-bisphosphatase
GIX96_RS22785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GIX96_RS22810	COG1575	Belongs to the MenA family. Type 1 subfamily
GIX96_RS22825	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GIX96_RS22830	COG1609	Transcriptional regulator
GIX96_RS22835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GIX96_RS22845	COG3209	COG3209 Rhs family protein
GIX96_RS22860	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GIX96_RS22870	COG0626	cystathionine gamma-synthase activity
GIX96_RS22875	COG0527	aspartate kinase activity
GIX96_RS22875	COG0460	homoserine dehydrogenase
GIX96_RS22880	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GIX96_RS22890	COG0697	spore germination
GIX96_RS22895	COG3738	Protein conserved in bacteria
GIX96_RS22900	COG0371	Dehydrogenase
GIX96_RS22905	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GIX96_RS22910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GIX96_RS22910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS22910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS22920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIX96_RS22925	COG1882	Formate acetyltransferase
GIX96_RS22930	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIX96_RS22935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIX96_RS22940	COG2207	Transcriptional regulator
GIX96_RS22945	COG2194	sulfuric ester hydrolase activity
GIX96_RS22960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GIX96_RS22970	COG0165	Argininosuccinate lyase
GIX96_RS22975	COG0583	DNA-binding transcription factor activity
GIX96_RS22980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GIX96_RS22985	COG1473	amidohydrolase
GIX96_RS22990	COG0477	Major facilitator Superfamily
GIX96_RS22995	COG1309	transcriptional regulator
GIX96_RS23005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GIX96_RS23010	COG4206	TonB-dependent receptor
GIX96_RS23015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GIX96_RS23040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GIX96_RS23045	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GIX96_RS23045	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GIX96_RS23080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GIX96_RS23085	COG0250	Participates in transcription elongation, termination and antitermination
GIX96_RS23125	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GIX96_RS23130	COG2022	thiamine diphosphate biosynthetic process
GIX96_RS23135	COG2104	thiamine diphosphate biosynthetic process
GIX96_RS23140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GIX96_RS23175	COG3068	Protein conserved in bacteria
GIX96_RS23190	COG3678	ATP-independent chaperone mediated protein folding
GIX96_RS23195	COG4191	Histidine kinase
GIX96_RS23200	COG2204	response regulator
GIX96_RS23205	COG0151	Belongs to the GarS family
GIX96_RS23235	COG0456	acetyltransferase
GIX96_RS23245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GIX96_RS23250	COG2224	Isocitrate lyase
GIX96_RS23265	COG1414	Transcriptional regulator
GIX96_RS23270	COG1410	methionine synthase
GIX96_RS23270	COG0646	methionine synthase
GIX96_RS23275	COG1283	sodium-dependent phosphate transmembrane transporter activity
GIX96_RS23320	COG1187	pseudouridine synthase activity
GIX96_RS23330	COG0527	aspartate kinase activity
GIX96_RS23355	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GIX96_RS23375	COG0477	Major facilitator Superfamily
GIX96_RS23375	COG2814	Major facilitator Superfamily
GIX96_RS23380	COG3833	ABC-type maltose transport systems, permease component
GIX96_RS23385	COG1175	transmembrane transport
GIX96_RS23390	COG2182	Extracellular solute-binding protein
GIX96_RS23395	COG3842	ATPase activity
GIX96_RS23410	COG1357	PFAM Pentapeptide repeats (8 copies)
GIX96_RS23430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GIX96_RS23440	COG0534	Mate efflux family protein
GIX96_RS23445	COG3237	CsbD-like
GIX96_RS23450	COG0735	belongs to the Fur family
GIX96_RS23460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GIX96_RS23470	COG0604	alcohol dehydrogenase
GIX96_RS23475	COG0305	Participates in initiation and elongation during chromosome replication
GIX96_RS23480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GIX96_RS23485	COG1448	Aminotransferase
GIX96_RS23495	COG3700	Belongs to the class B bacterial acid phosphatase family
GIX96_RS23500	COG0432	Pfam Uncharacterised protein family UPF0047
GIX96_RS23505	COG2315	Protein conserved in bacteria
GIX96_RS23510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GIX96_RS23515	COG0629	single-stranded DNA binding
GIX96_RS23525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GIX96_RS23530	COG2207	Transcriptional regulator
GIX96_RS23535	COG0789	Transcriptional regulator
GIX96_RS23540	COG2252	PERMEase
GIX96_RS23545	COG0025	NhaP-type Na H and K H
GIX96_RS23550	COG1357	PFAM Pentapeptide repeats (8 copies)
GIX96_RS23560	COG3162	membrane
GIX96_RS23565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GIX96_RS23575	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GIX96_RS23580	COG0437	4 iron, 4 sulfur cluster binding
GIX96_RS23585	COG3301	Polysulphide reductase, NrfD
GIX96_RS23590	COG1138	Cytochrome C-type biogenesis protein
GIX96_RS23595	COG3088	subunit of a heme lyase
GIX96_RS23600	COG4235	cytochrome complex assembly
GIX96_RS23605	COG1301	dicarboxylic acid transport
GIX96_RS23610	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GIX96_RS23620	COG1538	Outer membrane efflux protein
GIX96_RS23625	COG1289	transmembrane transporter activity
GIX96_RS23630	COG1566	PFAM secretion protein HlyD family protein
GIX96_RS23640	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GIX96_RS23650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIX96_RS23670	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS23675	COG1129	ABC transporter
GIX96_RS23690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GIX96_RS23695	COG0456	acetyltransferase
GIX96_RS23700	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GIX96_RS23705	COG3454	Phosphonate metabolism
GIX96_RS23710	COG4778	phosphonate C-P lyase system protein PhnL
GIX96_RS23715	COG4107	phosphonate C-P lyase system protein PhnK
GIX96_RS23720	COG3627	carbon phosphorus lyase activity
GIX96_RS23725	COG3626	phosphonate metabolism
GIX96_RS23730	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GIX96_RS23735	COG3624	Phosphonate C-P lyase system protein PhnG
GIX96_RS23740	COG2188	Transcriptional regulator
GIX96_RS23745	COG3639	organic phosphonate transmembrane transporter activity
GIX96_RS23750	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GIX96_RS23755	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GIX96_RS23760	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GIX96_RS23765	COG2824	Alkylphosphonate utilization operon protein PhnA
GIX96_RS23770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GIX96_RS23780	COG0477	Major facilitator Superfamily
GIX96_RS23790	COG0642	Histidine kinase
GIX96_RS23795	COG0745	RESPONSE REGULATOR receiver
GIX96_RS23800	COG2194	sulfuric ester hydrolase activity
GIX96_RS23805	COG0531	amino acid
GIX96_RS23810	COG2207	Transcriptional regulator
GIX96_RS23815	COG1982	Orn Lys Arg decarboxylase major
GIX96_RS23820	COG2169	Transcriptional regulator
GIX96_RS23825	COG1486	melibiose metabolic process
GIX96_RS23830	COG2211	Major facilitator Superfamily
GIX96_RS23835	COG3647	Membrane
GIX96_RS23840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GIX96_RS23840	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GIX96_RS23845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GIX96_RS23850	COG4565	transcriptional regulatory protein
GIX96_RS23855	COG3290	protein histidine kinase activity
GIX96_RS23860	COG3592	Divergent 4Fe-4S mono-cluster
GIX96_RS23865	COG2388	GCN5-related N-acetyl-transferase
GIX96_RS23880	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GIX96_RS23885	COG3104	oligopeptide transport
GIX96_RS23890	COG1982	Orn Lys Arg decarboxylase major
GIX96_RS23895	COG0531	amino acid
GIX96_RS23900	COG3710	Transcriptional regulator
GIX96_RS23910	COG1309	transcriptional regulator
GIX96_RS23915	COG4232	protein-disulfide reductase activity
GIX96_RS23925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GIX96_RS23930	COG1027	Aspartate ammonia-lyase
GIX96_RS23935	COG3030	protein affecting phage T7 exclusion by the F plasmid
GIX96_RS23940	COG0531	amino acid
GIX96_RS23965	COG1509	lysine 2,3-aminomutase activity
GIX96_RS23975	COG5510	response to toxic substance
GIX96_RS23980	COG5510	response to toxic substance
GIX96_RS23985	COG2076	Multidrug Resistance protein
GIX96_RS23990	COG3040	lipid binding
GIX96_RS23995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GIX96_RS24010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GIX96_RS24015	COG1053	succinate dehydrogenase
GIX96_RS24025	COG0531	amino acid
GIX96_RS24030	COG1511	domain protein
GIX96_RS24030	COG3264	Mechanosensitive ion channel
GIX96_RS24045	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GIX96_RS24075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GIX96_RS24075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GIX96_RS24080	COG0802	atpase or kinase
GIX96_RS24085	COG0860	N-Acetylmuramoyl-L-alanine amidase
GIX96_RS24090	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GIX96_RS24105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GIX96_RS24110	COG0330	HflC and HflK could
GIX96_RS24115	COG0330	HflC and HflK could
GIX96_RS24120	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GIX96_RS24135	COG0557	exoribonuclease II activity
GIX96_RS24140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GIX96_RS24145	COG3789	protein conserved in bacteria
GIX96_RS24150	COG1842	Phage shock protein A
GIX96_RS24160	COG3766	membrane
GIX96_RS24165	COG5463	Belongs to the UPF0441 family
GIX96_RS24170	COG0754	glutathionylspermidine amidase activity
GIX96_RS24175	COG1960	acyl-CoA dehydrogenase activity
GIX96_RS24185	COG3650	response to hydrogen peroxide
GIX96_RS24190	COG1073	alpha beta
GIX96_RS24205	COG3037	sugar-specific permease SgaT UlaA
GIX96_RS24210	COG3414	Phosphotransferase system galactitol-specific IIB component
GIX96_RS24215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS24250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GIX96_RS24275	COG0675	Transposase, IS605 OrfB family
GIX96_RS24285	COG3061	Opacity-associated protein A
GIX96_RS24290	COG0545	Peptidyl-prolyl cis-trans isomerase
GIX96_RS24295	COG1113	amino acid transport
GIX96_RS24305	COG0697	spore germination
GIX96_RS24310	COG0702	epimerase
GIX96_RS24315	COG1733	regulation of RNA biosynthetic process
GIX96_RS24320	COG0737	Belongs to the 5'-nucleotidase family
GIX96_RS24325	COG1218	3'(2'),5'-bisphosphate nucleotidase
GIX96_RS24335	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GIX96_RS24345	COG1253	flavin adenine dinucleotide binding
GIX96_RS24355	COG0729	surface antigen
GIX96_RS24360	COG2911	Protein conserved in bacteria
GIX96_RS24365	COG2105	PFAM AIG2 family protein
GIX96_RS24370	COG2336	PFAM SpoVT AbrB
GIX96_RS24375	COG2337	Toxic component of a toxin-antitoxin (TA) module
GIX96_RS24380	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GIX96_RS24385	COG1879	ABC-type sugar transport system periplasmic component
GIX96_RS24390	COG1129	ABC transporter
GIX96_RS24395	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS24400	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIX96_RS24410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GIX96_RS24420	COG0312	modulator of DNA gyrase
GIX96_RS24425	COG3783	Cytochrome b(562)
GIX96_RS24430	COG0602	queuosine metabolic process
GIX96_RS24435	COG1328	CTP reductase activity
GIX96_RS24440	COG0366	Alpha amylase catalytic
GIX96_RS24445	COG1263	PTS System
GIX96_RS24445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIX96_RS24450	COG1609	Transcriptional regulator
GIX96_RS24460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GIX96_RS24465	COG0251	oxidation-reduction process
GIX96_RS24485	COG0251	oxidation-reduction process
GIX96_RS24490	COG1028	Short-chain dehydrogenase reductase Sdr
GIX96_RS24495	COG1309	transcriptional regulator
GIX96_RS24500	COG2731	YhcH YjgK YiaL family protein
GIX96_RS24510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GIX96_RS24515	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GIX96_RS24520	COG0456	acetyltransferase
GIX96_RS24525	COG4269	membrane
GIX96_RS24535	COG2927	DNA polymerase III (CHI subunit)
GIX96_RS24545	COG0795	lipopolysaccharide-transporting ATPase activity
GIX96_RS24550	COG0795	lipopolysaccharide-transporting ATPase activity
GIX96_RS24555	COG0433	COG0433 Predicted ATPase
GIX96_RS24560	COG1064	alcohol dehydrogenase
GIX96_RS24615	COG0582	viral genome integration into host DNA
GIX96_RS24660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GIX96_RS24670	COG1111	helicase
GIX96_RS24670	COG1205	dead DEAH box helicase
GIX96_RS24675	COG0210	DNA helicase
GIX96_RS24690	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GIX96_RS24695	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GIX96_RS24700	COG0582	viral genome integration into host DNA
GIX96_RS24705	COG4974	Belongs to the 'phage' integrase family
GIX96_RS24710	COG3539	Fimbrial protein
GIX96_RS24715	COG3539	Fimbrial protein
GIX96_RS24720	COG3121	Chaperone
GIX96_RS24725	COG3188	usher protein
GIX96_RS24730	COG3539	Fimbrial protein
GIX96_RS24735	COG3539	Fimbrial protein
GIX96_RS24740	COG3539	Fimbrial protein
GIX96_RS24745	COG2610	gluconate transmembrane transporter activity
GIX96_RS24755	COG0246	Mannitol dehydrogenase
GIX96_RS24760	COG2186	Transcriptional regulator
GIX96_RS24785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GIX96_RS24790	COG0700	Nucleoside recognition
GIX96_RS24795	COG3366	ferrous iron transmembrane transporter activity
GIX96_RS24805	COG1470	cell adhesion involved in biofilm formation
GIX96_RS24805	COG1388	LysM domain
GIX96_RS24810	COG1388	LysM domain
GIX96_RS24810	COG2373	Large extracellular alpha-helical protein
GIX96_RS24810	COG4932	domain protein
GIX96_RS24815	COG0477	Major facilitator Superfamily
GIX96_RS24820	COG3204	pilus organization
GIX96_RS24835	COG1924	4 iron, 4 sulfur cluster binding
GIX96_RS24840	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GIX96_RS24845	COG2733	membrane
GIX96_RS24850	COG2814	Major facilitator Superfamily
GIX96_RS24860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GIX96_RS24865	COG5457	Domain of unknown function (DUF1127)
GIX96_RS24885	COG0732	type I restriction modification DNA specificity domain
GIX96_RS24910	COG0523	cobalamin synthesis protein
GIX96_RS24915	COG2879	small protein
GIX96_RS24920	COG1966	Carbon starvation protein
GIX96_RS24930	COG0840	transmembrane signaling receptor activity
GIX96_RS24935	COG2271	Major facilitator Superfamily
GIX96_RS24940	COG1802	Transcriptional regulator
GIX96_RS24945	COG1063	alcohol dehydrogenase
GIX96_RS24960	COG1484	DNA-dependent DNA replication
GIX96_RS24975	COG2966	Psort location CytoplasmicMembrane, score
GIX96_RS24980	COG2197	response regulator
GIX96_RS24985	COG2197	response regulator
GIX96_RS24990	COG4114	ferric iron reductase
GIX96_RS25010	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GIX96_RS25015	COG0456	acetyltransferase
GIX96_RS25020	COG1011	Hydrolase
GIX96_RS25030	COG2823	Periplasmic or secreted lipoprotein
GIX96_RS25040	COG4667	esterase of the alpha-beta hydrolase superfamily
GIX96_RS25045	COG0084	hydrolase, TatD family'
GIX96_RS25050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIX96_RS25085	COG3726	membrane protein affecting hemolysin expression
GIX96_RS25085	COG0095	Lipoate-protein ligase
GIX96_RS25095	COG0560	Phosphoserine phosphatase
GIX96_RS25100	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GIX96_RS25105	COG3172	ATPase kinase involved in NAD metabolism
GIX96_RS25105	COG1056	cytidyltransferase-related domain
GIX96_RS25110	COG0488	(ABC) transporter
GIX96_RS25115	COG0741	lytic transglycosylase activity
GIX96_RS25125	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GIX96_RS25135	COG2207	Transcriptional regulator
GIX96_RS25135	COG3708	Transcriptional regulator
GIX96_RS25140	COG3045	CreA protein
GIX96_RS25145	COG0745	RESPONSE REGULATOR receiver
GIX96_RS25150	COG2205	protein histidine kinase activity
GIX96_RS25155	COG4452	Inner membrane protein CreD
GIX96_RS25160	COG0745	RESPONSE REGULATOR receiver
GIX96_RS25170	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GIX96_RS25180	COG0460	homoserine dehydrogenase
GIX96_RS25180	COG0527	aspartate kinase activity
GIX96_RS25190	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GIX96_RS25205	COG1115	amino acid carrier protein
GIX96_RS25210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GIX96_RS25215	COG0521	Mo-molybdopterin cofactor biosynthetic process
GIX96_RS25220	COG1584	GPR1 FUN34 yaaH family protein
GIX96_RS25225	COG4735	regulation of single-species biofilm formation
GIX96_RS25255	COG0583	DNA-binding transcription factor activity
GIX96_RS25265	COG3188	usher protein
GIX96_RS25270	COG3121	Chaperone
GIX96_RS25295	COG0196	riboflavin kinase activity
GIX96_RS25310	COG1047	Peptidyl-prolyl cis-trans
GIX96_RS25330	COG0505	Belongs to the CarA family
GIX96_RS25335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GIX96_RS25350	COG1024	Enoyl-CoA hydratase
GIX96_RS25385	COG0644	oxidoreductase
GIX96_RS25390	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GIX96_RS25395	COG2271	Major facilitator Superfamily
GIX96_RS25410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GIX96_RS25445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GIX96_RS25450	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GIX96_RS25455	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GIX96_RS25460	COG1357	PFAM Pentapeptide repeats (8 copies)
GIX96_RS25470	COG0564	pseudouridine synthase activity
GIX96_RS25480	COG0417	DNA replication proofreading
GIX96_RS25485	COG0235	Class ii aldolase
GIX96_RS25500	COG4977	sequence-specific DNA binding
GIX96_RS25505	COG0586	Pfam SNARE associated Golgi protein
GIX96_RS25510	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GIX96_RS25515	COG1178	ABC-type Fe3 transport system permease component
GIX96_RS25520	COG4143	(ABC) transporter
GIX96_RS25530	COG4533	DNA binding
GIX96_RS25550	COG0473	3-isopropylmalate dehydrogenase activity
GIX96_RS25565	COG0583	DNA-binding transcription factor activity
GIX96_RS25570	COG0028	Belongs to the TPP enzyme family
GIX96_RS25575	COG0440	acetolactate synthase activity
GIX96_RS25585	COG1609	Transcriptional regulator
GIX96_RS25600	COG3116	cell division
GIX96_RS25605	COG0768	penicillin binding
GIX96_RS25610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GIX96_RS25615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GIX96_RS25625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GIX96_RS25630	COG0772	Belongs to the SEDS family
GIX96_RS25645	COG1181	Belongs to the D-alanine--D-alanine ligase family
GIX96_RS25650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GIX96_RS25655	COG0849	cell division
GIX96_RS25660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GIX96_RS25680	COG0494	nUDIX hydrolase
GIX96_RS25695	COG0237	dephospho-CoA kinase activity
GIX96_RS25705	COG1459	type II secretion system
GIX96_RS25710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GIX96_RS25715	COG4969	Belongs to the N-Me-Phe pilin family
GIX96_RS25720	COG0157	Belongs to the NadC ModD family
GIX96_RS25725	COG3023	N-Acetylmuramoyl-L-alanine amidase
GIX96_RS25730	COG3725	Membrane protein required for beta-lactamase induction
GIX96_RS25735	COG1113	amino acid transport
GIX96_RS25740	COG2186	Transcriptional regulator
GIX96_RS25745	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GIX96_RS25750	COG0508	dehydrogenase complex catalyzes the overall conversion of
GIX96_RS25755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GIX96_RS25760	COG3064	Membrane
GIX96_RS25765	COG1049	propionate catabolic process, 2-methylcitrate cycle
GIX96_RS25790	COG2132	Multicopper oxidase
GIX96_RS25795	COG4993	Dehydrogenase
GIX96_RS25800	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GIX96_RS25805	COG0288	reversible hydration of carbon dioxide
GIX96_RS25810	COG1131	(ABC) transporter
GIX96_RS25815	COG0842	Transport permease protein
GIX96_RS25820	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIX96_RS25825	COG0726	polysaccharide deacetylase
GIX96_RS25835	COG5464	transposase or invertase
GIX96_RS25860	COG3539	Fimbrial protein
GIX96_RS25865	COG3539	Fimbrial protein
GIX96_RS25870	COG3188	usher protein
GIX96_RS25875	COG3121	Chaperone
GIX96_RS25885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GIX96_RS25890	COG0617	tRNA 3'-terminal CCA addition
GIX96_RS25895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GIX96_RS25900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GIX96_RS25910	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GIX96_RS25915	COG1643	Atp-dependent helicase
GIX96_RS25920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GIX96_RS25925	COG4774	siderophore transport
GIX96_RS25930	COG1120	ATPase activity
GIX96_RS25935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GIX96_RS25940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIX96_RS25965	COG2860	membrane
GIX96_RS25970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GIX96_RS25985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GIX96_RS25990	COG3835	regulator
GIX96_RS26010	COG0024	Methionine aminopeptidase
GIX96_RS26035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GIX96_RS26040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GIX96_RS26045	COG0575	Belongs to the CDS family
GIX96_RS26050	COG0750	zinc metalloprotease
GIX96_RS26060	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GIX96_RS26065	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GIX96_RS26090	COG0587	DNA-directed DNA polymerase activity
GIX96_RS26100	COG1982	Orn Lys Arg decarboxylase major
GIX96_RS26105	COG0346	lactoylglutathione lyase activity
GIX96_RS26110	COG0037	tRNA processing
GIX96_RS26115	COG4568	rho-dependent transcription termination
GIX96_RS26130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GIX96_RS26135	COG3015	lipoprotein NlpE involved in copper resistance
GIX96_RS26140	COG0791	NLP P60 protein
GIX96_RS26150	COG1720	tRNA m6t6A37 methyltransferase activity
GIX96_RS26160	COG1464	Belongs to the NlpA lipoprotein family
GIX96_RS26165	COG2011	ABC-type metal ion transport system permease component
GIX96_RS26170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GIX96_RS26175	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GIX96_RS26245	COG1475	DNA binding
GIX96_RS26430	COG2274	protein secretion by the type I secretion system
GIX96_RS26500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GIX96_RS26525	COG3436	PFAM IS66 Orf2 family protein
GIX96_RS26530	COG4372	Transposase
GIX96_RS26540	COG1560	Kdo2-lipid A biosynthetic process
GIX96_RS26545	COG2194	sulfuric ester hydrolase activity
GIX96_RS26550	COG0297	glycogen (starch) synthase activity
GIX96_RS26555	COG0726	polysaccharide deacetylase
GIX96_RS26570	COG3468	outer membrane autotransporter barrel domain protein
GIX96_RS26655	COG1525	nuclease
GIX96_RS26665	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities