locus-tag	class	description
E3162_RS00015	COG3312	ion transport
E3162_RS00065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E3162_RS00090	COG3539	Fimbrial protein
E3162_RS00100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E3162_RS00105	COG0573	inorganic phosphate transmembrane transporter activity
E3162_RS00110	COG0581	inorganic phosphate transmembrane transporter activity
E3162_RS00115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E3162_RS00120	COG0704	Plays a role in the regulation of phosphate uptake
E3162_RS00145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3162_RS00150	COG2252	PERMEase
E3162_RS00155	COG0431	NADPH-dependent FMN reductase
E3162_RS00160	COG2091	lysine biosynthetic process via aminoadipic acid
E3162_RS00175	COG0814	amino acid
E3162_RS00230	COG0592	DNA-directed DNA polymerase activity
E3162_RS00240	COG0187	DNA topoisomerase II activity
E3162_RS00245	COG3753	Protein conserved in bacteria
E3162_RS00250	COG0561	phosphatase activity
E3162_RS00260	COG0644	oxidoreductase
E3162_RS00265	COG0823	Involved in the tonB-independent uptake of proteins
E3162_RS00270	COG5645	(Lipo)protein
E3162_RS00290	COG2188	Transcriptional regulator
E3162_RS00305	COG2207	Transcriptional regulator
E3162_RS00310	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3162_RS00315	COG3119	arylsulfatase activity
E3162_RS00325	COG2149	membrane
E3162_RS00335	COG0641	radical SAM
E3162_RS00340	COG2814	Major facilitator Superfamily
E3162_RS00355	COG0028	Belongs to the TPP enzyme family
E3162_RS00360	COG0440	acetolactate synthase activity
E3162_RS00380	COG2197	response regulator
E3162_RS00385	COG3851	Histidine kinase
E3162_RS00390	COG2271	Major facilitator Superfamily
E3162_RS00395	COG2271	Major facilitator Superfamily
E3162_RS00425	COG2814	Major facilitator Superfamily
E3162_RS00435	COG1464	Belongs to the NlpA lipoprotein family
E3162_RS00440	COG0697	spore germination
E3162_RS00445	COG2814	Major facilitator Superfamily
E3162_RS00610	COG5492	domain, Protein
E3162_RS00665	COG4372	Transposase
E3162_RS00670	COG3436	PFAM IS66 Orf2 family protein
E3162_RS00715	COG0582	viral genome integration into host DNA
E3162_RS00725	COG2211	Major facilitator Superfamily
E3162_RS00730	COG1501	Belongs to the glycosyl hydrolase 31 family
E3162_RS00735	COG2982	Protein involved in outer membrane biogenesis
E3162_RS00740	COG2233	PERMEase
E3162_RS00745	COG0786	glutamate:sodium symporter activity
E3162_RS00755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E3162_RS00760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3162_RS00765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3162_RS00775	COG0194	GDP metabolic process
E3162_RS00785	COG2860	membrane
E3162_RS00790	COG3645	SOS response
E3162_RS00795	COG1561	YicC-like family, N-terminal region
E3162_RS00820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3162_RS00850	COG1519	Transferase
E3162_RS00855	COG0859	PFAM glycosyl transferase family 9
E3162_RS00860	COG0438	transferase activity, transferring glycosyl groups
E3162_RS00865	COG0515	serine threonine protein kinase
E3162_RS00875	COG3642	lipopolysaccharide core region biosynthetic process
E3162_RS00895	COG0859	PFAM glycosyl transferase family 9
E3162_RS00900	COG0859	PFAM glycosyl transferase family 9
E3162_RS00915	COG0156	8-amino-7-oxononanoate synthase activity
E3162_RS00925	COG1216	Glycosyl transferase, family 2
E3162_RS00930	COG2861	carbohydrate metabolic process
E3162_RS00935	COG4942	peptidase
E3162_RS00945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3162_RS00950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3162_RS00965	COG1045	serine acetyltransferase
E3162_RS00970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E3162_RS00980	COG2186	Transcriptional regulator
E3162_RS00985	COG1620	l-lactate permease
E3162_RS00990	COG5295	Hep Hag repeat protein
E3162_RS01010	COG3722	fumarate hydratase activity
E3162_RS01020	COG2213	PTS system mannitol-specific
E3162_RS01020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS01030	COG1566	PFAM secretion protein HlyD family protein
E3162_RS01040	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E3162_RS01045	COG3209	COG3209 Rhs family protein
E3162_RS01050	COG0625	glutathione transferase activity
E3162_RS01060	COG3276	selenocysteine insertion sequence binding
E3162_RS01065	COG1454	alcohol dehydrogenase
E3162_RS01075	COG1012	belongs to the aldehyde dehydrogenase family
E3162_RS01085	COG1566	PFAM secretion protein HlyD family protein
E3162_RS01090	COG0583	DNA-binding transcription factor activity
E3162_RS01095	COG3713	MltA-interacting MipA family protein
E3162_RS01105	COG2211	Major facilitator Superfamily
E3162_RS01115	COG1414	Transcriptional regulator
E3162_RS01120	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3162_RS01125	COG3977	Valine--pyruvate aminotransferase
E3162_RS01130	COG0366	Alpha amylase catalytic
E3162_RS01135	COG2992	FlgJ-related protein
E3162_RS01140	COG1609	Transcriptional regulator
E3162_RS01140	COG2207	Transcriptional regulator
E3162_RS01145	COG4214	carbohydrate transport
E3162_RS01155	COG4213	ABC transporter substrate-binding protein
E3162_RS01165	COG1070	Carbohydrate kinase
E3162_RS01170	COG4682	membrane
E3162_RS01175	COG4682	membrane
E3162_RS01180	COG3274	enterobacterial common antigen metabolic process
E3162_RS01205	COG1278	Cold shock
E3162_RS01210	COG2944	sequence-specific DNA binding
E3162_RS01225	COG2885	chlorophyll binding
E3162_RS01230	COG0243	molybdopterin cofactor binding
E3162_RS01235	COG0456	acetyltransferase
E3162_RS01240	COG2818	Glycosylase
E3162_RS01245	COG5571	outer membrane autotransporter
E3162_RS01250	COG2223	nitrite transmembrane transporter activity
E3162_RS01255	COG3539	Fimbrial protein
E3162_RS01260	COG3121	Chaperone
E3162_RS01270	COG3539	Fimbrial protein
E3162_RS01275	COG3539	Fimbrial protein
E3162_RS01280	COG2194	sulfuric ester hydrolase activity
E3162_RS01290	COG0747	negative chemotaxis
E3162_RS01295	COG0601	transmembrane transport
E3162_RS01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3162_RS01305	COG0444	Belongs to the ABC transporter superfamily
E3162_RS01310	COG4608	Belongs to the ABC transporter superfamily
E3162_RS01315	COG0814	amino acid
E3162_RS01325	COG2194	sulfuric ester hydrolase activity
E3162_RS01355	COG1215	transferase activity, transferring glycosyl groups
E3162_RS01360	COG1215	transferase activity, transferring glycosyl groups
E3162_RS01365	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
E3162_RS01370	COG3118	belongs to the thioredoxin family
E3162_RS01370	COG0457	Tetratricopeptide repeat
E3162_RS01375	COG2200	EAL domain
E3162_RS01375	COG2199	diguanylate cyclase activity
E3162_RS01385	COG0612	Peptidase, M16
E3162_RS01395	COG2200	EAL domain
E3162_RS01400	COG2982	Protein involved in outer membrane biogenesis
E3162_RS01405	COG0477	Major facilitator Superfamily
E3162_RS01410	COG1295	ribonuclease BN
E3162_RS01415	COG0583	DNA-binding transcription factor activity
E3162_RS01420	COG2197	response regulator
E3162_RS01430	COG1858	cytochrome C peroxidase
E3162_RS01435	COG0076	glutamate decarboxylase activity
E3162_RS01440	COG2207	Transcriptional regulator
E3162_RS01445	COG2207	Transcriptional regulator
E3162_RS01450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3162_RS01455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3162_RS01465	COG2771	luxR family
E3162_RS01470	COG3247	response to pH
E3162_RS01485	COG1285	pathogenesis
E3162_RS01490	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
E3162_RS01495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3162_RS01505	COG3721	Heme iron utilization protein
E3162_RS01515	COG4558	Periplasmic binding protein
E3162_RS01525	COG4771	TonB-dependent receptor
E3162_RS01530	COG3720	iron ion transport
E3162_RS01535	COG2197	response regulator
E3162_RS01540	COG3065	identical protein binding
E3162_RS01550	COG1393	Belongs to the ArsC family
E3162_RS01555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E3162_RS01560	COG0640	Transcriptional regulator
E3162_RS01570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3162_RS01575	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E3162_RS01580	COG0339	signal peptide processing
E3162_RS01590	COG3104	oligopeptide transport
E3162_RS01595	COG0589	response to stress
E3162_RS01605	COG0306	phosphate transporter
E3162_RS01610	COG2081	HI0933 family
E3162_RS01630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3162_RS01635	COG1129	ABC transporter
E3162_RS01635	COG0842	Transport permease protein
E3162_RS01640	COG0842	Transport permease protein
E3162_RS01655	COG0191	fructose-bisphosphate aldolase activity
E3162_RS01670	COG3775	system Galactitol-specific IIC component
E3162_RS01675	COG3414	Phosphotransferase system galactitol-specific IIB component
E3162_RS01685	COG2188	Transcriptional regulator
E3162_RS01695	COG1124	(ABC) transporter
E3162_RS01700	COG0444	Belongs to the ABC transporter superfamily
E3162_RS01705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3162_RS01710	COG0601	transmembrane transport
E3162_RS01715	COG0747	negative chemotaxis
E3162_RS01720	COG2091	lysine biosynthetic process via aminoadipic acid
E3162_RS01725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3162_RS01730	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS01740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3162_RS01765	COG1216	Glycosyl transferase, family 2
E3162_RS01785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E3162_RS01795	COG0204	Acyl-transferase
E3162_RS01815	COG0628	permease
E3162_RS01830	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3162_RS01845	COG3714	YhhN family
E3162_RS01855	COG3776	membrane
E3162_RS01860	COG0742	ribosomal rna small subunit methyltransferase
E3162_RS01865	COG0552	protein localization to endoplasmic reticulum
E3162_RS01870	COG2884	Cell division ATP-binding protein ftsE
E3162_RS01875	COG2177	Part of the ABC transporter FtsEX involved in
E3162_RS01880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3162_RS01885	COG0683	leucine binding
E3162_RS01900	COG0456	acetyltransferase
E3162_RS01905	COG0683	leucine binding
E3162_RS01910	COG0559	Belongs to the binding-protein-dependent transport system permease family
E3162_RS01915	COG4177	L-phenylalanine transmembrane transporter activity
E3162_RS01920	COG0411	ABC transporter
E3162_RS01925	COG0410	ABC transporter
E3162_RS01935	COG1653	transport
E3162_RS01940	COG1175	transmembrane transport
E3162_RS01950	COG3842	ATPase activity
E3162_RS01955	COG0584	glycerophosphoryl diester phosphodiesterase
E3162_RS01965	COG0405	Gamma-glutamyltransferase
E3162_RS01975	COG1247	-acetyltransferase
E3162_RS01980	COG0673	inositol 2-dehydrogenase activity
E3162_RS01985	COG1741	Belongs to the pirin family
E3162_RS01990	COG1609	Transcriptional regulator
E3162_RS01995	COG3265	gluconokinase activity
E3162_RS02000	COG2610	gluconate transmembrane transporter activity
E3162_RS02005	COG0514	ATP-dependent DNA helicase (RecQ)
E3162_RS02025	COG2095	MarC family integral membrane protein
E3162_RS02030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3162_RS02035	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E3162_RS02055	COG0058	SHG alpha-glucan phosphorylase activity
E3162_RS02060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E3162_RS02075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E3162_RS02090	COG1349	DNA-binding transcription factor activity
E3162_RS02095	COG4650	regulator
E3162_RS02100	COG1690	Belongs to the RtcB family
E3162_RS02125	COG0058	SHG alpha-glucan phosphorylase activity
E3162_RS02130	COG1640	4-alpha-glucanotransferase
E3162_RS02135	COG2610	gluconate transmembrane transporter activity
E3162_RS02145	COG1040	competence protein
E3162_RS02155	COG5464	transposase or invertase
E3162_RS02165	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
E3162_RS02170	COG1918	ferrous iron import across plasma membrane
E3162_RS02175	COG2183	response to ionizing radiation
E3162_RS02180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3162_RS02185	COG0745	RESPONSE REGULATOR receiver
E3162_RS02190	COG2205	protein histidine kinase activity
E3162_RS02200	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E3162_RS02210	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3162_RS02215	COG1011	Hydrolase
E3162_RS02225	COG0494	nUDIX hydrolase
E3162_RS02230	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E3162_RS02235	COG4972	Pilus assembly protein
E3162_RS02240	COG3166	PFAM Fimbrial assembly family protein
E3162_RS02255	COG4796	Type ii and iii secretion system protein
E3162_RS02270	COG3266	domain, Protein
E3162_RS02275	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E3162_RS02280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3162_RS02285	COG0546	phosphoglycolate phosphatase activity
E3162_RS02290	COG0180	Tryptophanyl-tRNA synthetase
E3162_RS02295	COG2188	Transcriptional regulator
E3162_RS02305	COG1082	Xylose isomerase domain protein TIM barrel
E3162_RS02310	COG2222	sugar isomerase
E3162_RS02315	COG0531	amino acid
E3162_RS02330	COG2116	formate transmembrane transporter activity
E3162_RS02335	COG2146	nitrite reductase [NAD(P)H] activity
E3162_RS02340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3162_RS02350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E3162_RS02360	COG2184	nucleotidyltransferase activity
E3162_RS02365	COG0512	Glutamine amidotransferase of anthranilate synthase
E3162_RS02370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E3162_RS02375	COG1289	transmembrane transporter activity
E3162_RS02380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3162_RS02385	COG1765	OsmC-like protein
E3162_RS02390	COG3954	Phosphoribulokinase
E3162_RS02400	COG0429	hydrolase of the alpha beta-hydrolase fold
E3162_RS02405	COG0488	(ABC) transporter
E3162_RS02420	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E3162_RS02425	COG1047	Peptidyl-prolyl cis-trans
E3162_RS02435	COG0545	Peptidyl-prolyl cis-trans isomerase
E3162_RS02440	COG2964	Protein conserved in bacteria
E3162_RS02510	COG0089	rRNA binding
E3162_RS02600	COG0201	protein transport
E3162_RS02640	COG0789	Transcriptional regulator
E3162_RS02645	COG3036	rescue of stalled ribosome
E3162_RS02655	COG0569	domain protein
E3162_RS02685	COG0551	DNA topoisomerase type I activity
E3162_RS02690	COG0009	L-threonylcarbamoyladenylate synthase
E3162_RS02705	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E3162_RS02745	COG1126	abc transporter atp-binding protein
E3162_RS02750	COG0765	amino acid transport
E3162_RS02755	COG4597	amino acid ABC transporter
E3162_RS02760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3162_RS02775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3162_RS02780	COG1309	transcriptional regulator
E3162_RS02790	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E3162_RS02800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3162_RS02810	COG4145	pantothenate transmembrane transporter activity
E3162_RS02815	COG3924	membrane
E3162_RS02820	COG0439	Biotin carboxylase
E3162_RS02825	COG0511	ligase activity, forming carbon-carbon bonds
E3162_RS02830	COG0604	alcohol dehydrogenase
E3162_RS02835	COG2199	diguanylate cyclase activity
E3162_RS02835	COG2200	EAL domain
E3162_RS02840	COG1077	Cell shape determining protein MreB Mrl
E3162_RS02845	COG1792	Involved in formation and maintenance of cell shape
E3162_RS02850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E3162_RS02855	COG0424	maF-like protein
E3162_RS02860	COG1530	ribonuclease E activity
E3162_RS02865	COG3164	Protein of unknown function
E3162_RS02870	COG0312	modulator of DNA gyrase
E3162_RS02875	COG0583	DNA-binding transcription factor activity
E3162_RS02895	COG2732	(Barnase) inhibitor
E3162_RS02915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3162_RS02920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3162_RS02925	COG3105	Protein conserved in bacteria
E3162_RS02930	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E3162_RS02945	COG0625	glutathione transferase activity
E3162_RS02950	COG2969	positive regulation of protein catabolic process
E3162_RS02955	COG3069	C4-dicarboxylate transmembrane transporter activity
E3162_RS02985	COG2731	YhcH YjgK YiaL family protein
E3162_RS02995	COG0493	'glutamate synthase
E3162_RS03000	COG0070	glutamate synthase
E3162_RS03000	COG0069	glutamate synthase activity
E3162_RS03000	COG0067	glutamate synthase
E3162_RS03005	COG1242	4 iron, 4 sulfur cluster binding
E3162_RS03010	COG5002	protein histidine kinase activity
E3162_RS03010	COG0784	Response regulator, receiver
E3162_RS03010	COG2198	Histidine kinase
E3162_RS03015	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E3162_RS03025	COG0515	serine threonine protein kinase
E3162_RS03030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS03045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E3162_RS03050	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
E3162_RS03055	COG1137	ATPase activity
E3162_RS03060	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E3162_RS03065	COG3117	lipopolysaccharide transmembrane transporter activity
E3162_RS03070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E3162_RS03075	COG0517	IMP dehydrogenase activity
E3162_RS03075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E3162_RS03080	COG0530	calcium, potassium:sodium antiporter activity
E3162_RS03085	COG1127	ABC transporter
E3162_RS03090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3162_RS03095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3162_RS03100	COG2854	intermembrane phospholipid transfer
E3162_RS03105	COG3113	response to antibiotic
E3162_RS03110	COG5007	Belongs to the BolA IbaG family
E3162_RS03120	COG3423	Transcriptional regulator
E3162_RS03125	COG0142	geranyltranstransferase activity
E3162_RS03140	COG0697	spore germination
E3162_RS03150	COG2027	D-alanyl-D-alanine carboxypeptidase
E3162_RS03155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3162_RS03160	COG1534	Rna-binding protein
E3162_RS03170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3162_RS03175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E3162_RS03185	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3162_RS03195	COG2194	sulfuric ester hydrolase activity
E3162_RS03215	COG0195	Participates in both transcription termination and antitermination
E3162_RS03255	COG0513	Belongs to the DEAD box helicase family
E3162_RS03260	COG0814	amino acid
E3162_RS03265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3162_RS03270	COG0826	peptidase U32
E3162_RS03275	COG0826	peptidase U32
E3162_RS03280	COG3154	lipid carrier protein
E3162_RS03285	COG3153	acetyltransferase
E3162_RS03295	COG3787	Belongs to the UPF0306 family
E3162_RS03300	COG0693	protein deglycase activity
E3162_RS03305	COG0702	epimerase
E3162_RS03310	COG0701	Predicted permease
E3162_RS03315	COG2823	Periplasmic or secreted lipoprotein
E3162_RS03335	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3162_RS03355	COG3121	Chaperone
E3162_RS03360	COG3539	Fimbrial protein
E3162_RS03370	COG3716	PTS system mannose fructose sorbose family IID component
E3162_RS03380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3162_RS03390	COG2222	sugar isomerase
E3162_RS03395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3162_RS03400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS03405	COG3716	PTS system mannose fructose sorbose family IID component
E3162_RS03415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3162_RS03425	COG1349	DNA-binding transcription factor activity
E3162_RS03435	COG2002	toxin-antitoxin pair type II binding
E3162_RS03440	COG2721	sulfolactate sulfo-lyase activity
E3162_RS03445	COG2271	Major facilitator Superfamily
E3162_RS03455	COG2084	Dehydrogenase
E3162_RS03460	COG1929	Belongs to the glycerate kinase type-1 family
E3162_RS03485	COG0583	DNA-binding transcription factor activity
E3162_RS03490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E3162_RS03500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E3162_RS03505	COG1882	Formate acetyltransferase
E3162_RS03510	COG0251	oxidation-reduction process
E3162_RS03515	COG1760	l-serine dehydratase
E3162_RS03520	COG0814	amino acid
E3162_RS03535	COG1741	Belongs to the pirin family
E3162_RS03540	COG0583	DNA-binding transcription factor activity
E3162_RS03545	COG3152	Membrane
E3162_RS03550	COG3152	Membrane
E3162_RS03555	COG0435	Glutathione S-transferase
E3162_RS03560	COG2259	Doxx family
E3162_RS03570	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E3162_RS03575	COG4575	ribosome binding
E3162_RS03580	COG1422	Protein of unknown function (DUF1090)
E3162_RS03590	COG0586	Pfam SNARE associated Golgi protein
E3162_RS03595	COG2186	Transcriptional regulator
E3162_RS03600	COG2271	Major facilitator Superfamily
E3162_RS03610	COG2721	sulfolactate sulfo-lyase activity
E3162_RS03620	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
E3162_RS03625	COG0861	Integral membrane protein TerC family
E3162_RS03630	COG0673	inositol 2-dehydrogenase activity
E3162_RS03635	COG2949	membrane
E3162_RS03640	COG1451	nucleotide metabolic process
E3162_RS03650	COG4680	protein conserved in bacteria
E3162_RS03655	COG5499	transcription regulator containing HTH domain
E3162_RS03660	COG1902	pentaerythritol trinitrate reductase activity
E3162_RS03660	COG0446	pyridine nucleotide-disulphide oxidoreductase
E3162_RS03665	COG3408	Glycogen debranching enzyme
E3162_RS03665	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
E3162_RS03675	COG0531	amino acid
E3162_RS03680	COG2731	YhcH YjgK YiaL family protein
E3162_RS03685	COG3250	beta-galactosidase activity
E3162_RS03690	COG1609	Transcriptional regulator
E3162_RS03695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3162_RS03705	COG0840	transmembrane signaling receptor activity
E3162_RS03710	COG1695	Transcriptional regulator
E3162_RS03715	COG2375	cellular response to nickel ion
E3162_RS03730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E3162_RS03735	COG0358	DNA primase activity
E3162_RS03740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E3162_RS03750	COG0471	metal ion transport
E3162_RS03755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3162_RS03760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3162_RS03765	COG0583	DNA-binding transcription factor activity
E3162_RS03775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E3162_RS03790	COG4991	sh3 domain protein
E3162_RS03795	COG3025	triphosphatase activity
E3162_RS03820	COG2268	Band 7 protein
E3162_RS03825	COG1585	Membrane protein implicated in regulation of membrane protease activity
E3162_RS03855	COG3384	dioxygenase
E3162_RS03860	COG0754	glutathionylspermidine amidase activity
E3162_RS03870	COG1538	Outer membrane efflux protein
E3162_RS03875	COG0494	nUDIX hydrolase
E3162_RS03880	COG3151	Protein conserved in bacteria
E3162_RS03885	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E3162_RS03890	COG3150	esterase
E3162_RS03895	COG0187	DNA topoisomerase II activity
E3162_RS03900	COG4774	siderophore transport
E3162_RS03905	COG1120	ATPase activity
E3162_RS03910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3162_RS03915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3162_RS03925	COG1737	Transcriptional regulator
E3162_RS03930	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E3162_RS03935	COG2249	NAD(P)H dehydrogenase (quinone) activity
E3162_RS03940	COG0642	Histidine kinase
E3162_RS03945	COG0745	RESPONSE REGULATOR receiver
E3162_RS03950	COG3111	PFAM Bacterial OB fold (BOF) protein
E3162_RS03955	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E3162_RS03960	COG4166	transmembrane transport
E3162_RS03965	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E3162_RS03970	COG0204	Acyl-transferase
E3162_RS03975	COG2132	Multicopper oxidase
E3162_RS03980	COG1032	radical SAM domain protein
E3162_RS03985	COG4238	major outer membrane lipoprotein
E3162_RS03995	COG0656	L-ascorbic acid biosynthetic process
E3162_RS04000	COG1979	alcohol dehydrogenase
E3162_RS04005	COG2207	Transcriptional regulator
E3162_RS04010	COG0586	Pfam SNARE associated Golgi protein
E3162_RS04015	COG0626	cystathionine gamma-synthase activity
E3162_RS04020	COG0811	peptide transport
E3162_RS04025	COG0848	biopolymer transport protein
E3162_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS04040	COG0667	Aldo Keto reductase
E3162_RS04055	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3162_RS04060	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS04065	COG5557	Pfam Polysulphide reductase, NrfD
E3162_RS04070	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E3162_RS04075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3162_RS04080	COG1773	rubredoxin
E3162_RS04085	COG0375	protein maturation
E3162_RS04090	COG0298	carbon dioxide binding
E3162_RS04095	COG0625	glutathione transferase activity
E3162_RS04100	COG0754	glutathionylspermidine amidase activity
E3162_RS04125	COG3436	PFAM IS66 Orf2 family protein
E3162_RS04130	COG4372	Transposase
E3162_RS04135	COG3436	PFAM IS66 Orf2 family protein
E3162_RS04200	COG3436	PFAM IS66 Orf2 family protein
E3162_RS04215	COG0582	viral genome integration into host DNA
E3162_RS04225	COG1811	Na channel or pump
E3162_RS04230	COG1982	Orn Lys Arg decarboxylase major
E3162_RS04235	COG2211	Major facilitator Superfamily
E3162_RS04250	COG1194	a g-specific adenine glycosylase
E3162_RS04260	COG3171	Protein conserved in bacteria
E3162_RS04270	COG0252	asparaginase activity
E3162_RS04280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3162_RS04285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
E3162_RS04295	COG0762	integral membrane protein
E3162_RS04300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3162_RS04305	COG2805	Type II/IV secretion system protein
E3162_RS04320	COG0189	ligase activity
E3162_RS04325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3162_RS04330	COG2356	endonuclease I
E3162_RS04335	COG3091	SprT-like family
E3162_RS04340	COG2814	Major facilitator Superfamily
E3162_RS04360	COG1166	arginine decarboxylase activity
E3162_RS04375	COG0501	Belongs to the peptidase M48B family
E3162_RS04380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E3162_RS04385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS04390	COG2213	PTS system mannitol-specific
E3162_RS04395	COG1063	alcohol dehydrogenase
E3162_RS04400	COG1494	fructose-1,6-bisphosphatase
E3162_RS04410	COG1072	(Pantothenic acid kinase))
E3162_RS04415	COG1122	ATPase activity
E3162_RS04420	COG1122	ATPase activity
E3162_RS04445	COG0126	phosphoglycerate kinase activity
E3162_RS04450	COG0191	fructose-bisphosphate aldolase activity
E3162_RS04455	COG0668	transmembrane transport
E3162_RS04465	COG2968	Membrane
E3162_RS04475	COG0427	acetyl-CoA hydrolase
E3162_RS04480	COG1024	Enoyl-CoA hydratase
E3162_RS04485	COG1703	isobutyryl-CoA mutase activity
E3162_RS04490	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E3162_RS04490	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E3162_RS04505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3162_RS04520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3162_RS04540	COG0006	proline dipeptidase activity
E3162_RS04545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3162_RS04550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3162_RS04575	COG2723	6-phospho-beta-galactosidase activity
E3162_RS04585	COG1272	protein, Hemolysin III
E3162_RS04595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
E3162_RS04605	COG0716	FMN binding
E3162_RS04610	COG4974	Belongs to the 'phage' integrase family
E3162_RS04615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3162_RS04620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3162_RS04630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E3162_RS04650	COG2233	PERMEase
E3162_RS04660	COG2252	PERMEase
E3162_RS04665	COG0402	S-adenosylhomocysteine deaminase activity
E3162_RS04670	COG2233	PERMEase
E3162_RS04675	COG2080	2 iron, 2 sulfur cluster binding
E3162_RS04675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E3162_RS04680	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E3162_RS04685	COG0402	S-adenosylhomocysteine deaminase activity
E3162_RS04690	COG0493	'glutamate synthase
E3162_RS04690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3162_RS04695	COG2068	MobA-Related Protein
E3162_RS04700	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E3162_RS04705	COG3608	succinylglutamate desuccinylase aspartoacylase
E3162_RS04705	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
E3162_RS04710	COG0549	Belongs to the carbamate kinase family
E3162_RS04720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3162_RS04725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E3162_RS04730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E3162_RS04740	COG2080	2 iron, 2 sulfur cluster binding
E3162_RS04745	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E3162_RS04750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E3162_RS04755	COG4942	peptidase
E3162_RS04775	COG2207	Transcriptional regulator
E3162_RS04880	COG2197	response regulator
E3162_RS04885	COG0741	lytic transglycosylase activity
E3162_RS04895	COG0457	Tetratricopeptide repeat
E3162_RS04895	COG3710	Transcriptional regulator
E3162_RS04900	COG0457	Tetratricopeptide repeat
E3162_RS04925	COG3710	Transcriptional regulator
E3162_RS04930	COG2771	luxR family
E3162_RS04935	COG0814	amino acid
E3162_RS04940	COG0183	Belongs to the thiolase family
E3162_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS04955	COG2814	Major facilitator Superfamily
E3162_RS04960	COG1794	racemase activity, acting on amino acids and derivatives
E3162_RS04965	COG0583	DNA-binding transcription factor activity
E3162_RS04975	COG1609	Transcriptional regulator
E3162_RS04990	COG0667	Aldo Keto reductase
E3162_RS05000	COG0861	Integral membrane protein TerC family
E3162_RS05015	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
E3162_RS05030	COG2165	general secretion pathway protein
E3162_RS05035	COG4795	General secretion pathway protein
E3162_RS05045	COG4967	type IV pilus modification protein PilV
E3162_RS05050	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E3162_RS05055	COG1025	Belongs to the peptidase M16 family
E3162_RS05060	COG1074	ATP-dependent DNA helicase activity
E3162_RS05065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3162_RS05070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E3162_RS05070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
E3162_RS05075	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3162_RS05095	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E3162_RS05100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3162_RS05105	COG2166	iron-sulfur cluster assembly
E3162_RS05110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3162_RS05120	COG0583	DNA-binding transcription factor activity
E3162_RS05125	COG2363	Small membrane protein
E3162_RS05135	COG1349	DNA-binding transcription factor activity
E3162_RS05145	COG1070	Carbohydrate kinase
E3162_RS05155	COG0738	Major facilitator superfamily
E3162_RS05160	COG0235	Class ii aldolase
E3162_RS05165	COG1454	alcohol dehydrogenase
E3162_RS05175	COG1760	l-serine dehydratase
E3162_RS05180	COG0814	amino acid
E3162_RS05185	COG1611	Belongs to the LOG family
E3162_RS05200	COG3098	single-species biofilm formation
E3162_RS05205	COG0564	pseudouridine synthase activity
E3162_RS05210	COG0716	FMN binding
E3162_RS05215	COG2271	Major facilitator Superfamily
E3162_RS05225	COG4948	Mandelate Racemase Muconate Lactonizing
E3162_RS05230	COG3437	response regulator, receiver
E3162_RS05230	COG4999	Histidine kinase
E3162_RS05230	COG2205	protein histidine kinase activity
E3162_RS05230	COG3850	Histidine kinase
E3162_RS05235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E3162_RS05240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3162_RS05245	COG2336	PFAM SpoVT AbrB
E3162_RS05250	COG2337	Toxic component of a toxin-antitoxin (TA) module
E3162_RS05255	COG3956	TIGRFAM MazG family protein
E3162_RS05270	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
E3162_RS05280	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
E3162_RS05290	COG0602	queuosine metabolic process
E3162_RS05295	COG1070	Carbohydrate kinase
E3162_RS05300	COG2223	nitrite transmembrane transporter activity
E3162_RS05305	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS05310	COG0277	FAD linked oxidase domain protein
E3162_RS05320	COG2086	electron transfer activity
E3162_RS05330	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3162_RS05335	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3162_RS05340	COG0644	oxidoreductase
E3162_RS05345	COG0720	synthase
E3162_RS05350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3162_RS05370	COG1203	CRISPR-associated helicase, Cas3
E3162_RS05385	COG1857	crispr-associated protein
E3162_RS05400	COG1518	maintenance of DNA repeat elements
E3162_RS05405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3162_RS05410	COG2234	aminopeptidase activity
E3162_RS05465	COG1388	LysM domain
E3162_RS05465	COG4942	peptidase
E3162_RS05475	COG1846	Transcriptional regulator
E3162_RS05480	COG0163	prenyltransferase activity
E3162_RS05485	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E3162_RS05495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E3162_RS05515	COG3604	Transcriptional regulator
E3162_RS05520	COG0309	Hydrogenase expression formation protein (HypE)
E3162_RS05525	COG0409	Hydrogenase expression formation protein
E3162_RS05530	COG0298	carbon dioxide binding
E3162_RS05535	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E3162_RS05540	COG0375	protein maturation
E3162_RS05550	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3162_RS05555	COG0651	ATP synthesis coupled electron transport
E3162_RS05560	COG0650	Formate hydrogenlyase subunit 4
E3162_RS05565	COG3261	NADH dehydrogenase
E3162_RS05565	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E3162_RS05570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3162_RS05575	COG3260	NADH ubiquinone oxidoreductase 20
E3162_RS05585	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3162_RS05590	COG2723	6-phospho-beta-galactosidase activity
E3162_RS05595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3162_RS05595	COG1263	PTS System
E3162_RS05600	COG1609	Transcriptional regulator
E3162_RS05605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3162_RS05610	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E3162_RS05630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E3162_RS05630	COG0517	IMP dehydrogenase activity
E3162_RS05635	COG1349	DNA-binding transcription factor activity
E3162_RS05640	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS05645	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS05665	COG2951	lytic endotransglycosylase activity
E3162_RS05670	COG1546	Belongs to the CinA family
E3162_RS05685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E3162_RS05690	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E3162_RS05720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3162_RS05725	COG1238	metal cluster binding
E3162_RS05740	COG2814	Major facilitator Superfamily
E3162_RS05745	COG1566	PFAM secretion protein HlyD family protein
E3162_RS05750	COG1846	Transcriptional regulator
E3162_RS05760	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E3162_RS05765	COG2814	Major facilitator Superfamily
E3162_RS05770	COG2113	Glycine betaine
E3162_RS05775	COG4176	ABC-type proline glycine betaine transport system permease component
E3162_RS05780	COG4175	Glycine betaine
E3162_RS05785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3162_RS05790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3162_RS05800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3162_RS05805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3162_RS05815	COG4575	ribosome binding
E3162_RS05830	COG2916	Histone family protein nucleoid-structuring protein H-NS
E3162_RS05835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3162_RS05840	COG0640	Transcriptional regulator
E3162_RS05845	COG0401	homolog of Blt101
E3162_RS05850	COG1652	LysM domain
E3162_RS05855	COG1802	Transcriptional regulator
E3162_RS05860	COG1113	amino acid transport
E3162_RS05865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3162_RS05870	COG1012	belongs to the aldehyde dehydrogenase family
E3162_RS05875	COG0579	oxidoreductase
E3162_RS05910	COG3468	outer membrane autotransporter barrel domain protein
E3162_RS05960	COG2826	transposase and inactivated derivatives, IS30 family
E3162_RS06020	COG3436	PFAM IS66 Orf2 family protein
E3162_RS06080	COG2867	negative regulation of translational initiation
E3162_RS06090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3162_RS06095	COG0497	DNA recombination
E3162_RS06110	COG4536	flavin adenine dinucleotide binding
E3162_RS06115	COG4137	Cytochrome C assembly protein
E3162_RS06120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3162_RS06145	COG2885	chlorophyll binding
E3162_RS06150	COG2199	diguanylate cyclase activity
E3162_RS06165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E3162_RS06170	COG0287	Prephenate dehydrogenase
E3162_RS06170	COG1605	Chorismate mutase
E3162_RS06175	COG0077	Prephenate dehydratase
E3162_RS06175	COG1605	Chorismate mutase
E3162_RS06185	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E3162_RS06190	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3162_RS06195	COG0564	pseudouridine synthase activity
E3162_RS06205	COG0542	response to heat
E3162_RS06230	COG0477	Major facilitator Superfamily
E3162_RS06235	COG5544	Lipoprotein
E3162_RS06240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3162_RS06245	COG0045	succinate-CoA ligase (ADP-forming) activity
E3162_RS06245	COG1042	CoA-binding domain protein
E3162_RS06245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3162_RS06255	COG3118	belongs to the thioredoxin family
E3162_RS06260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3162_RS06275	COG1280	lysine exporter protein (LysE YggA)
E3162_RS06280	COG0583	DNA-binding transcription factor activity
E3162_RS06285	COG0513	Belongs to the DEAD box helicase family
E3162_RS06290	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3162_RS06295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E3162_RS06305	COG1595	DNA-templated transcription, initiation
E3162_RS06310	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
E3162_RS06315	COG3026	antisigma factor binding
E3162_RS06320	COG3086	response to oxidative stress
E3162_RS06330	COG0681	Belongs to the peptidase S26 family
E3162_RS06350	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
E3162_RS06365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3162_RS06370	COG1737	Transcriptional regulator
E3162_RS06375	COG0560	Phosphoserine phosphatase
E3162_RS06380	COG0590	tRNA wobble adenosine to inosine editing
E3162_RS06385	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
E3162_RS06390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3162_RS06390	COG0047	phosphoribosylformylglycinamidine synthase activity
E3162_RS06395	COG2205	protein histidine kinase activity
E3162_RS06400	COG3170	Tfp pilus assembly protein FimV
E3162_RS06405	COG2204	response regulator
E3162_RS06410	COG0347	Belongs to the P(II) protein family
E3162_RS06415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3162_RS06415	COG1017	nitric oxide dioxygenase activity
E3162_RS06425	COG1940	carbohydrate kinase activity
E3162_RS06430	COG0457	Tetratricopeptide repeat
E3162_RS06435	COG1879	ABC-type sugar transport system periplasmic component
E3162_RS06440	COG1129	ABC transporter
E3162_RS06445	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3162_RS06450	COG1063	alcohol dehydrogenase
E3162_RS06455	COG1063	alcohol dehydrogenase
E3162_RS06460	COG2017	converts alpha-aldose to the beta-anomer
E3162_RS06465	COG2259	Doxx family
E3162_RS06490	COG4638	Rieske (2fe-2S)
E3162_RS06495	COG0583	DNA-binding transcription factor activity
E3162_RS06500	COG2814	Major facilitator Superfamily
E3162_RS06505	COG3711	transcriptional antiterminator
E3162_RS06510	COG1073	alpha beta
E3162_RS06515	COG0483	inositol monophosphate 1-phosphatase activity
E3162_RS06535	COG0822	iron-sulfur transferase activity
E3162_RS06555	COG0633	Ferredoxin
E3162_RS06560	COG2975	iron-sulfur cluster assembly
E3162_RS06575	COG2897	thiosulfate sulfurtransferase activity
E3162_RS06580	COG2373	Large extracellular alpha-helical protein
E3162_RS06585	COG4953	penicillin-binding protein 1C
E3162_RS06590	COG0243	molybdopterin cofactor binding
E3162_RS06595	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS06600	COG3302	dmso reductase anchor subunit
E3162_RS06635	COG2976	Protein conserved in bacteria
E3162_RS06650	COG1645	bacterial-type flagellum-dependent swarming motility
E3162_RS06660	COG0516	GMP reductase activity
E3162_RS06660	COG0517	IMP dehydrogenase activity
E3162_RS06675	COG3133	Outer membrane lipoprotein
E3162_RS06690	COG2200	EAL domain
E3162_RS06695	COG0248	Ppx GppA phosphatase
E3162_RS06700	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
E3162_RS06705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E3162_RS06720	COG2233	PERMEase
E3162_RS06730	COG1393	Belongs to the ArsC family
E3162_RS06735	COG4783	chaperone-mediated protein folding
E3162_RS06740	COG0628	permease
E3162_RS06745	COG2116	formate transmembrane transporter activity
E3162_RS06750	COG3604	Transcriptional regulator
E3162_RS06760	COG3260	NADH ubiquinone oxidoreductase 20
E3162_RS06765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3162_RS06770	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E3162_RS06770	COG3261	NADH dehydrogenase
E3162_RS06775	COG0651	ATP synthesis coupled electron transport
E3162_RS06780	COG4237	Hydrogenase 4 membrane
E3162_RS06785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3162_RS06790	COG0650	Formate hydrogenlyase subunit 4
E3162_RS06795	COG0651	ATP synthesis coupled electron transport
E3162_RS06800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3162_RS06805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3162_RS06810	COG2716	regulation of RNA biosynthetic process
E3162_RS06820	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E3162_RS06830	COG2321	neutral zinc metallopeptidase
E3162_RS06840	COG0400	carboxylic ester hydrolase activity
E3162_RS06855	COG1393	Belongs to the ArsC family
E3162_RS06865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3162_RS06870	COG3850	Histidine kinase
E3162_RS06875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3162_RS06875	COG0493	'glutamate synthase
E3162_RS06885	COG5342	invasion associated locus B
E3162_RS06890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E3162_RS06895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3162_RS06900	COG0281	malic enzyme
E3162_RS06900	COG0280	phosphate acetyltransferase
E3162_RS06905	COG4810	utilization protein
E3162_RS06910	COG4917	ethanolamine utilization protein
E3162_RS06915	COG4766	ethanolamine catabolic process
E3162_RS06920	COG4812	Cobalamin adenosyltransferase
E3162_RS06925	COG0280	phosphate acetyltransferase
E3162_RS06930	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E3162_RS06935	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
E3162_RS06940	COG1012	belongs to the aldehyde dehydrogenase family
E3162_RS06945	COG4820	ethanolamine utilization protein (EutJ)
E3162_RS06950	COG1454	alcohol dehydrogenase
E3162_RS06955	COG3192	ethanolamine utilization protein
E3162_RS06960	COG4819	ethanolamine utilization protein
E3162_RS06965	COG4303	Ethanolamine ammonia lyase large subunit
E3162_RS06975	COG4816	utilization protein
E3162_RS06980	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E3162_RS06985	COG2207	Transcriptional regulator
E3162_RS06995	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3162_RS07015	COG2837	iron assimilation
E3162_RS07020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3162_RS07025	COG1263	PTS System
E3162_RS07025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3162_RS07040	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS07045	COG4150	thiosulfate binding
E3162_RS07050	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
E3162_RS07055	COG4208	sulfate ABC transporter
E3162_RS07060	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
E3162_RS07065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3162_RS07080	COG2190	(PTS) system
E3162_RS07085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3162_RS07090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS07095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3162_RS07115	COG3530	Putative quorum-sensing-regulated virulence factor
E3162_RS07120	COG0385	Bile acid
E3162_RS07125	COG0583	DNA-binding transcription factor activity
E3162_RS07165	COG0675	Transposase, IS605 OrfB family
E3162_RS07170	COG3415	Transposase
E3162_RS07175	COG3415	Transposase
E3162_RS07190	COG2200	EAL domain
E3162_RS07190	COG2199	diguanylate cyclase activity
E3162_RS07195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3162_RS07220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3162_RS07225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3162_RS07230	COG0006	proline dipeptidase activity
E3162_RS07235	COG1363	Peptidase, m42
E3162_RS07240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3162_RS07240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS07240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS07245	COG2207	Transcriptional regulator
E3162_RS07250	COG3279	Response regulator of the LytR AlgR family
E3162_RS07255	COG3275	phosphorelay sensor kinase activity
E3162_RS07260	COG0436	Aminotransferase
E3162_RS07270	COG1560	Kdo2-lipid A biosynthetic process
E3162_RS07295	COG0028	Belongs to the TPP enzyme family
E3162_RS07300	COG0679	Auxin Efflux Carrier
E3162_RS07305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E3162_RS07310	COG2205	protein histidine kinase activity
E3162_RS07310	COG0784	Response regulator, receiver
E3162_RS07310	COG2198	Histidine kinase
E3162_RS07310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3162_RS07315	COG2197	response regulator
E3162_RS07320	COG1566	PFAM secretion protein HlyD family protein
E3162_RS07325	COG0477	Major facilitator Superfamily
E3162_RS07400	COG0582	viral genome integration into host DNA
E3162_RS07610	COG3772	lysozyme
E3162_RS07770	COG2116	formate transmembrane transporter activity
E3162_RS07775	COG2853	Lipoprotein
E3162_RS07785	COG2067	long-chain fatty acid transport protein
E3162_RS07790	COG3691	Protein conserved in bacteria
E3162_RS07805	COG2062	phosphohistidine phosphatase, SixA
E3162_RS07810	COG3539	Fimbrial protein
E3162_RS07815	COG3188	usher protein
E3162_RS07820	COG3121	Chaperone
E3162_RS07825	COG3539	Fimbrial protein
E3162_RS07830	COG3539	Fimbrial protein
E3162_RS07835	COG3539	Fimbrial protein
E3162_RS07865	COG0730	response to heat
E3162_RS07870	COG3101	peptidyl-lysine hydroxylation
E3162_RS07880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E3162_RS07880	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
E3162_RS07885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3162_RS07890	COG2814	Major facilitator Superfamily
E3162_RS07905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3162_RS07915	COG0586	Pfam SNARE associated Golgi protein
E3162_RS07925	COG0285	dihydrofolate synthase activity
E3162_RS07930	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E3162_RS07935	COG1286	toxin biosynthetic process
E3162_RS07940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E3162_RS07945	COG0163	prenyltransferase activity
E3162_RS07950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3162_RS07955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3162_RS07960	COG4215	(ABC) transporter
E3162_RS07965	COG4160	amino acid transport
E3162_RS07970	COG4598	ABC transporter
E3162_RS07975	COG5464	transposase or invertase
E3162_RS07980	COG1090	epimerase
E3162_RS07985	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E3162_RS07990	COG0625	glutathione transferase activity
E3162_RS07995	COG0625	glutathione transferase activity
E3162_RS08000	COG0622	Phosphoesterase
E3162_RS08005	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
E3162_RS08010	COG1288	antiporter activity
E3162_RS08015	COG0280	phosphate acetyltransferase
E3162_RS08015	COG0857	belongs to the CobB CobQ family
E3162_RS08020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E3162_RS08035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3162_RS08040	COG0471	metal ion transport
E3162_RS08040	COG0490	domain, Protein
E3162_RS08050	COG0436	Aminotransferase
E3162_RS08055	COG0583	DNA-binding transcription factor activity
E3162_RS08075	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
E3162_RS08080	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E3162_RS08085	COG1034	ATP synthesis coupled electron transport
E3162_RS08100	COG0839	Belongs to the complex I subunit 6 family
E3162_RS08110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3162_RS08115	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3162_RS08140	COG5160	protein modification by small protein removal
E3162_RS08145	COG1234	tRNA 3'-trailer cleavage
E3162_RS08150	COG2153	protein acetylation
E3162_RS08155	COG4575	ribosome binding
E3162_RS08160	COG1169	isochorismate synthase
E3162_RS08175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
E3162_RS08185	COG0318	PFAM AMP-dependent synthetase and ligase
E3162_RS08230	COG0406	alpha-ribazole phosphatase activity
E3162_RS08250	COG1414	Transcriptional regulator
E3162_RS08255	COG4948	Mandelate Racemase Muconate Lactonizing
E3162_RS08260	COG2271	Major facilitator Superfamily
E3162_RS08265	COG2271	Major facilitator Superfamily
E3162_RS08270	COG3836	Belongs to the HpcH HpaI aldolase family
E3162_RS08275	COG5464	transposase or invertase
E3162_RS08280	COG0247	lactate metabolic process
E3162_RS08290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E3162_RS08295	COG2271	Major facilitator Superfamily
E3162_RS08300	COG0584	glycerophosphoryl diester phosphodiesterase
E3162_RS08310	COG0583	DNA-binding transcription factor activity
E3162_RS08315	COG2814	Major facilitator Superfamily
E3162_RS08320	COG3642	lipopolysaccharide core region biosynthetic process
E3162_RS08325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3162_RS08330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3162_RS08335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3162_RS08340	COG3468	outer membrane autotransporter barrel domain protein
E3162_RS08350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E3162_RS08355	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
E3162_RS08360	COG3234	Protein of unknown function (DUF1175)
E3162_RS08365	COG2373	Large extracellular alpha-helical protein
E3162_RS08370	COG5445	Predicted secreted protein (DUF2300)
E3162_RS08375	COG5445	Predicted secreted protein (DUF2300)
E3162_RS08380	COG4676	Protein conserved in bacteria
E3162_RS08385	COG0784	Response regulator, receiver
E3162_RS08385	COG2205	protein histidine kinase activity
E3162_RS08390	COG2197	response regulator
E3162_RS08395	COG2198	Histidine kinase
E3162_RS08395	COG0642	Histidine kinase
E3162_RS08400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3162_RS08405	COG1477	protein flavinylation
E3162_RS08410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3162_RS08410	COG2169	Transcriptional regulator
E3162_RS08415	COG3145	DNA-N1-methyladenine dioxygenase activity
E3162_RS08420	COG4615	Cyclic peptide transporter
E3162_RS08435	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3162_RS08435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3162_RS08440	COG3062	negative regulation of establishment of protein localization
E3162_RS08450	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS08455	COG0348	domain, Protein
E3162_RS08460	COG3043	anaerobic respiration
E3162_RS08465	COG3005	denitrification pathway
E3162_RS08470	COG4133	protoheme IX ABC transporter activity
E3162_RS08475	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3162_RS08480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3162_RS08485	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3162_RS08495	COG1138	Cytochrome C-type biogenesis protein
E3162_RS08500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3162_RS08505	COG3088	subunit of a heme lyase
E3162_RS08505	COG4235	cytochrome complex assembly
E3162_RS08510	COG2197	response regulator
E3162_RS08515	COG3468	outer membrane autotransporter barrel domain protein
E3162_RS08525	COG3083	sulfuric ester hydrolase activity
E3162_RS08545	COG1061	Type III restriction enzyme res subunit
E3162_RS08550	COG1187	pseudouridine synthase activity
E3162_RS08555	COG2814	Major facilitator Superfamily
E3162_RS08565	COG4172	Belongs to the ABC transporter superfamily
E3162_RS08570	COG4239	(ABC) transporter, permease
E3162_RS08575	COG4174	ABC transporter (Permease)
E3162_RS08580	COG4166	transmembrane transport
E3162_RS08585	COG2200	EAL domain
E3162_RS08590	COG0791	NLP P60 protein
E3162_RS08595	COG0671	phosphoesterase, PA-phosphatase related
E3162_RS08600	COG0523	cobalamin synthesis protein
E3162_RS08620	COG2814	Major facilitator Superfamily
E3162_RS08625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS08625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS08630	COG1105	Belongs to the carbohydrate kinase PfkB family
E3162_RS08635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3162_RS08635	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E3162_RS08635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3162_RS08640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3162_RS08645	COG2313	pseudouridylate synthase activity
E3162_RS08650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3162_RS08655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3162_RS08665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3162_RS08670	COG1522	sequence-specific DNA binding
E3162_RS08670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3162_RS08680	COG2855	membrane
E3162_RS08685	COG0583	DNA-binding transcription factor activity
E3162_RS08690	COG0833	amino acid
E3162_RS08695	COG4771	TonB-dependent receptor
E3162_RS08700	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
E3162_RS08710	COG2311	Membrane
E3162_RS08715	COG1609	Transcriptional regulator
E3162_RS08720	COG1879	ABC-type sugar transport system periplasmic component
E3162_RS08725	COG1129	ABC transporter
E3162_RS08730	COG4211	Belongs to the binding-protein-dependent transport system permease family
E3162_RS08735	COG0167	dihydroorotate dehydrogenase activity
E3162_RS08735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
E3162_RS08740	COG0493	'glutamate synthase
E3162_RS08750	COG2949	membrane
E3162_RS08760	COG1346	cytolysis
E3162_RS08775	COG2271	Major facilitator Superfamily
E3162_RS08790	COG0625	glutathione transferase activity
E3162_RS08795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3162_RS08800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3162_RS08810	COG1538	Outer membrane efflux protein
E3162_RS08815	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS08830	COG1686	Belongs to the peptidase S11 family
E3162_RS08835	COG0277	FAD linked oxidase domain protein
E3162_RS08840	COG1472	Belongs to the glycosyl hydrolase 3 family
E3162_RS08845	COG1732	Glycine betaine
E3162_RS08850	COG1174	glycine betaine transport
E3162_RS08855	COG1125	glycine betaine transport
E3162_RS08860	COG1174	glycine betaine transport
E3162_RS08870	COG0789	Transcriptional regulator
E3162_RS08875	COG0582	viral genome integration into host DNA
E3162_RS09120	COG0740	serine-type endopeptidase activity
E3162_RS09160	COG4372	Transposase
E3162_RS09165	COG3436	PFAM IS66 Orf2 family protein
E3162_RS09215	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS09240	COG3275	phosphorelay sensor kinase activity
E3162_RS09245	COG3279	Response regulator of the LytR AlgR family
E3162_RS09250	COG4807	Protein conserved in bacteria
E3162_RS09255	COG4808	Protein conserved in bacteria
E3162_RS09260	COG4715	Zinc finger, swim domain protein
E3162_RS09265	COG3552	Protein containing von Willebrand factor type A (VWA) domain
E3162_RS09270	COG2425	protein containing a von Willebrand factor type A (vWA) domain
E3162_RS09275	COG2425	protein containing a von Willebrand factor type A (vWA) domain
E3162_RS09280	COG0714	Associated with various cellular activities
E3162_RS09290	COG3831	ATPase activity
E3162_RS09320	COG0489	protein tyrosine kinase activity
E3162_RS09330	COG3539	Fimbrial protein
E3162_RS09335	COG3121	Chaperone
E3162_RS09340	COG3188	usher protein
E3162_RS09345	COG3539	Fimbrial protein
E3162_RS09350	COG5455	response to cobalt ion
E3162_RS09355	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E3162_RS09385	COG0351	phosphomethylpyrimidine kinase
E3162_RS09390	COG3757	hydrolase, family 25
E3162_RS09395	COG2188	Transcriptional regulator
E3162_RS09400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3162_RS09405	COG1397	ADP-ribosylglycohydrolase
E3162_RS09410	COG2211	Major facilitator Superfamily
E3162_RS09415	COG1830	Aldolase
E3162_RS09430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS09435	COG3414	Phosphotransferase system galactitol-specific IIB component
E3162_RS09440	COG3775	system Galactitol-specific IIC component
E3162_RS09445	COG1063	alcohol dehydrogenase
E3162_RS09465	COG4974	Belongs to the 'phage' integrase family
E3162_RS09530	COG4695	Portal protein
E3162_RS09625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E3162_RS09640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E3162_RS09690	COG3422	double-strand break repair
E3162_RS09695	COG0745	RESPONSE REGULATOR receiver
E3162_RS09700	COG2205	protein histidine kinase activity
E3162_RS09715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3162_RS09740	COG4245	von Willebrand factor, type A
E3162_RS09745	COG0631	protein serine/threonine phosphatase activity
E3162_RS09750	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
E3162_RS09755	COG0443	Heat shock 70 kDa protein
E3162_RS09760	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E3162_RS09770	COG0572	uridine kinase
E3162_RS09780	COG2982	Protein involved in outer membrane biogenesis
E3162_RS09795	COG1253	flavin adenine dinucleotide binding
E3162_RS09805	COG1596	polysaccharide export
E3162_RS09810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E3162_RS09815	COG0489	protein tyrosine kinase activity
E3162_RS09815	COG3206	protein involved in exopolysaccharide biosynthesis
E3162_RS09820	COG0463	Glycosyl transferase, family 2
E3162_RS09825	COG1045	serine acetyltransferase
E3162_RS09830	COG0438	transferase activity, transferring glycosyl groups
E3162_RS09840	COG1216	Glycosyl transferase, family 2
E3162_RS09845	COG0110	maltose O-acetyltransferase activity
E3162_RS09850	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E3162_RS09855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3162_RS09860	COG1051	belongs to the nudix hydrolase family
E3162_RS09865	COG0297	glycogen (starch) synthase activity
E3162_RS09870	COG0662	Cupin 2, conserved barrel domain protein
E3162_RS09870	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
E3162_RS09875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E3162_RS09880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3162_RS09885	COG2244	polysaccharide biosynthetic process
E3162_RS09890	COG2327	Polysaccharide pyruvyl transferase
E3162_RS09895	COG0438	transferase activity, transferring glycosyl groups
E3162_RS09905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3162_RS09910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E3162_RS09935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3162_RS09945	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E3162_RS09950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3162_RS09955	COG1051	belongs to the nudix hydrolase family
E3162_RS09960	COG0662	Cupin 2, conserved barrel domain protein
E3162_RS09960	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
E3162_RS09965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E3162_RS09975	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
E3162_RS09980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
E3162_RS10005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
E3162_RS10010	COG0131	Imidazoleglycerol-phosphate dehydratase
E3162_RS10010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3162_RS10020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
E3162_RS10035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3162_RS10040	COG0583	DNA-binding transcription factor activity
E3162_RS10050	COG0531	amino acid
E3162_RS10055	COG2391	methyltransferase activity
E3162_RS10060	COG0425	Belongs to the sulfur carrier protein TusA family
E3162_RS10065	COG2925	Exonuclease
E3162_RS10070	COG0582	viral genome integration into host DNA
E3162_RS10325	COG3772	lysozyme
E3162_RS10430	COG1185	polyribonucleotide nucleotidyltransferase activity
E3162_RS10465	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS10475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
E3162_RS10485	COG1686	Belongs to the peptidase S11 family
E3162_RS10495	COG1289	transmembrane transporter activity
E3162_RS10505	COG4917	ethanolamine utilization protein
E3162_RS10540	COG2003	Belongs to the UPF0758 family
E3162_RS10585	COG4771	TonB-dependent receptor
E3162_RS10590	COG4372	Transposase
E3162_RS10595	COG3436	PFAM IS66 Orf2 family protein
E3162_RS10605	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
E3162_RS10620	COG1376	ErfK ybiS ycfS ynhG family protein
E3162_RS10630	COG0583	DNA-binding transcription factor activity
E3162_RS10635	COG0583	DNA-binding transcription factor activity
E3162_RS10645	COG0534	Mate efflux family protein
E3162_RS10655	COG0217	transcriptional regulatory protein
E3162_RS10660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E3162_RS10665	COG0477	Major facilitator Superfamily
E3162_RS10675	COG4932	domain protein
E3162_RS10675	COG1388	LysM domain
E3162_RS10675	COG2373	Large extracellular alpha-helical protein
E3162_RS10705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3162_RS10750	COG1846	Transcriptional regulator
E3162_RS10795	COG1403	HNH endonuclease
E3162_RS10800	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3162_RS10855	COG3772	lysozyme
E3162_RS10895	COG3436	PFAM IS66 Orf2 family protein
E3162_RS10900	COG4372	Transposase
E3162_RS10995	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS11015	COG3038	cytochrome b561
E3162_RS11020	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3162_RS11035	COG2351	hydroxyisourate hydrolase activity
E3162_RS11040	COG0745	RESPONSE REGULATOR receiver
E3162_RS11045	COG2205	protein histidine kinase activity
E3162_RS11065	COG1418	mRNA catabolic process
E3162_RS11070	COG0270	DNA (cytosine-5-)-methyltransferase activity
E3162_RS11075	COG3727	T/G mismatch-specific endonuclease activity
E3162_RS11080	COG0697	spore germination
E3162_RS11085	COG2354	Protein conserved in bacteria
E3162_RS11090	COG5475	Uncharacterized small protein (DUF2158)
E3162_RS11095	COG3706	GGDEF domain
E3162_RS11115	COG2197	response regulator
E3162_RS11120	COG1684	flagellar biosynthetic protein fliR
E3162_RS11125	COG1987	bacterial-type flagellum assembly
E3162_RS11130	COG1338	Plays a role in the flagellum-specific transport system
E3162_RS11135	COG3190	flagellar
E3162_RS11140	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E3162_RS11145	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E3162_RS11150	COG1580	Controls the rotational direction of flagella during chemotaxis
E3162_RS11155	COG3144	bacterial-type flagellum assembly
E3162_RS11160	COG2882	bacterial-type flagellum organization
E3162_RS11165	COG1157	protein secretion by the type III secretion system
E3162_RS11170	COG1317	bacterial-type flagellum organization
E3162_RS11175	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E3162_RS11180	COG1766	The M ring may be actively involved in energy transduction
E3162_RS11195	COG0454	-acetyltransferase
E3162_RS11205	COG0454	-acetyltransferase
E3162_RS11210	COG2135	peptidase activity
E3162_RS11215	COG0425	Belongs to the sulfur carrier protein TusA family
E3162_RS11220	COG2391	methyltransferase activity
E3162_RS11230	COG0366	Alpha amylase catalytic
E3162_RS11240	COG1516	flagellar protein fliS
E3162_RS11245	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
E3162_RS11255	COG1191	sigma factor activity
E3162_RS11285	COG2197	response regulator
E3162_RS11300	COG2197	response regulator
E3162_RS11340	COG2826	transposase and inactivated derivatives, IS30 family
E3162_RS11385	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E3162_RS11485	COG4974	Belongs to the 'phage' integrase family
E3162_RS11490	COG3012	SEC-C Motif Domain Protein
E3162_RS11490	COG3318	Belongs to the UPF0149 family
E3162_RS11495	COG0814	amino acid
E3162_RS11505	COG1528	Iron-storage protein
E3162_RS11525	COG1528	Iron-storage protein
E3162_RS11530	COG1879	ABC-type sugar transport system periplasmic component
E3162_RS11535	COG1129	ABC transporter
E3162_RS11540	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3162_RS11545	COG1877	trehalose-phosphatase activity
E3162_RS11555	COG0589	response to stress
E3162_RS11570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E3162_RS11575	COG1360	Flagellar Motor Protein
E3162_RS11580	COG0643	Histidine kinase
E3162_RS11580	COG2198	Histidine kinase
E3162_RS11585	COG0835	chemotaxis
E3162_RS11590	COG0840	transmembrane signaling receptor activity
E3162_RS11595	COG0840	transmembrane signaling receptor activity
E3162_RS11600	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
E3162_RS11605	COG2201	protein-glutamate methylesterase activity
E3162_RS11610	COG0745	RESPONSE REGULATOR receiver
E3162_RS11620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E3162_RS11625	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E3162_RS11635	COG3755	Protein conserved in bacteria
E3162_RS11645	COG3102	Protein conserved in bacteria
E3162_RS11655	COG3005	denitrification pathway
E3162_RS11660	COG0243	molybdopterin cofactor binding
E3162_RS11675	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E3162_RS11680	COG1801	Protein of unknown function DUF72
E3162_RS11685	COG1335	isochorismatase
E3162_RS11695	COG0494	nUDIX hydrolase
E3162_RS11700	COG0217	transcriptional regulatory protein
E3162_RS11730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3162_RS11740	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E3162_RS11745	COG0739	heme binding
E3162_RS11750	COG1560	Kdo2-lipid A biosynthetic process
E3162_RS11755	COG0469	pyruvate kinase activity
E3162_RS11760	COG1737	Transcriptional regulator
E3162_RS11765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3162_RS11770	COG0129	dihydroxy-acid dehydratase activity
E3162_RS11775	COG0800	Aldolase
E3162_RS11780	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
E3162_RS11785	COG3141	response to X-ray
E3162_RS11795	COG2979	Protein of unknown function (DUF533)
E3162_RS11800	COG1770	oligopeptidase
E3162_RS11805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3162_RS11810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3162_RS11820	COG2372	response to copper ion
E3162_RS11825	COG1276	copper resistance
E3162_RS11835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E3162_RS11855	COG3008	intermembrane lipid transfer
E3162_RS11860	COG2995	paraquat-inducible protein a
E3162_RS11865	COG1956	GAF domain-containing protein
E3162_RS11875	COG0793	Belongs to the peptidase S41A family
E3162_RS11885	COG2814	Major facilitator Superfamily
E3162_RS11890	COG1414	Transcriptional regulator
E3162_RS11920	COG2226	methyltransferase
E3162_RS11935	COG3716	PTS system mannose fructose sorbose family IID component
E3162_RS11940	COG3715	PTS system
E3162_RS11945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS11945	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3162_RS11950	COG1253	flavin adenine dinucleotide binding
E3162_RS11955	COG2200	EAL domain
E3162_RS11960	COG1760	l-serine dehydratase
E3162_RS11970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3162_RS11985	COG0251	oxidation-reduction process
E3162_RS11990	COG1199	ATP-dependent helicase activity
E3162_RS11995	COG1214	PFAM Peptidase M22, glycoprotease
E3162_RS12000	COG3065	identical protein binding
E3162_RS12005	COG0318	PFAM AMP-dependent synthetase and ligase
E3162_RS12010	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E3162_RS12015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3162_RS12020	COG4638	Rieske (2fe-2S)
E3162_RS12025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3162_RS12030	COG0473	3-isopropylmalate dehydrogenase activity
E3162_RS12035	COG0583	DNA-binding transcription factor activity
E3162_RS12040	COG1280	lysine exporter protein (LysE YggA)
E3162_RS12045	COG3615	Tellurite resistance protein tehB
E3162_RS12055	COG2261	transglycosylase associated protein
E3162_RS12070	COG2203	Gaf domain
E3162_RS12070	COG2199	diguanylate cyclase activity
E3162_RS12075	COG3042	response to heat
E3162_RS12080	COG3189	MarR family transcriptional regulator
E3162_RS12085	COG2807	transmembrane transport
E3162_RS12090	COG2207	Transcriptional regulator
E3162_RS12105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3162_RS12110	COG2199	diguanylate cyclase activity
E3162_RS12115	COG2199	diguanylate cyclase activity
E3162_RS12125	COG2766	serine protein kinase
E3162_RS12130	COG3713	MltA-interacting MipA family protein
E3162_RS12135	COG0656	L-ascorbic acid biosynthetic process
E3162_RS12140	COG0676	glucose-6-phosphate 1-epimerase activity
E3162_RS12145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E3162_RS12155	COG3139	Protein of unknown function (DUF1315)
E3162_RS12160	COG1063	alcohol dehydrogenase
E3162_RS12165	COG2271	Major facilitator Superfamily
E3162_RS12170	COG1063	alcohol dehydrogenase
E3162_RS12175	COG0191	fructose-bisphosphate aldolase activity
E3162_RS12180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3162_RS12185	COG0667	Aldo Keto reductase
E3162_RS12190	COG1349	DNA-binding transcription factor activity
E3162_RS12200	COG1335	isochorismatase
E3162_RS12205	COG0252	asparaginase activity
E3162_RS12215	COG0616	signal peptide processing
E3162_RS12220	COG0778	Nitroreductase
E3162_RS12225	COG0709	Synthesizes selenophosphate from selenide and ATP
E3162_RS12230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E3162_RS12240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E3162_RS12250	COG0494	nUDIX hydrolase
E3162_RS12255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E3162_RS12260	COG2897	thiosulfate sulfurtransferase activity
E3162_RS12265	COG4136	ATPase activity
E3162_RS12270	COG4135	transport system, permease component
E3162_RS12275	COG4134	Bacterial extracellular solute-binding protein
E3162_RS12280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3162_RS12285	COG0398	Pfam SNARE associated Golgi protein
E3162_RS12295	COG0398	Pfam SNARE associated Golgi protein
E3162_RS12300	COG0708	Exodeoxyribonuclease III
E3162_RS12330	COG3678	ATP-independent chaperone mediated protein folding
E3162_RS12340	COG0322	excinuclease ABC activity
E3162_RS12350	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3162_RS12355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E3162_RS12360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E3162_RS12365	COG1447	Phosphotransferase system cellobiose-specific component IIA
E3162_RS12370	COG1917	Cupin 2, conserved barrel domain protein
E3162_RS12370	COG2169	Transcriptional regulator
E3162_RS12375	COG1486	melibiose metabolic process
E3162_RS12385	COG0753	catalase activity
E3162_RS12405	COG1988	membrane-bound metal-dependent
E3162_RS12410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3162_RS12420	COG3001	Fructosamine kinase
E3162_RS12430	COG1105	Belongs to the carbohydrate kinase PfkB family
E3162_RS12435	COG3137	Salt-induced outer membrane protein
E3162_RS12480	COG0072	phenylalanine-tRNA ligase activity
E3162_RS12480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3162_RS12495	COG0386	Belongs to the glutathione peroxidase family
E3162_RS12505	COG0791	NLP P60 protein
E3162_RS12510	COG2200	EAL domain
E3162_RS12520	COG4256	Hemin uptake protein
E3162_RS12525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E3162_RS12535	COG0574	Belongs to the PEP-utilizing enzyme family
E3162_RS12535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3162_RS12540	COG0318	PFAM AMP-dependent synthetase and ligase
E3162_RS12545	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3162_RS12550	COG0644	oxidoreductase
E3162_RS12555	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E3162_RS12560	COG2086	electron transfer activity
E3162_RS12565	COG2207	Transcriptional regulator
E3162_RS12565	COG1917	Cupin 2, conserved barrel domain protein
E3162_RS12570	COG1960	acyl-CoA dehydrogenase activity
E3162_RS12575	COG4670	ketone body catabolic process
E3162_RS12590	COG2271	Major facilitator Superfamily
E3162_RS12610	COG0628	permease
E3162_RS12615	COG0277	FAD linked oxidase domain protein
E3162_RS12615	COG0247	lactate metabolic process
E3162_RS12620	COG2050	protein possibly involved in aromatic compounds catabolism
E3162_RS12630	COG0316	Belongs to the HesB IscA family
E3162_RS12635	COG0719	Fe-S assembly protein
E3162_RS12640	COG0396	ATPase activity
E3162_RS12645	COG0719	Fe-S assembly protein
E3162_RS12660	COG1376	ErfK ybiS ycfS ynhG family protein
E3162_RS12665	COG4238	major outer membrane lipoprotein
E3162_RS12670	COG0469	pyruvate kinase activity
E3162_RS12680	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS12685	COG2414	aldehyde ferredoxin oxidoreductase
E3162_RS12695	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS12700	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
E3162_RS12710	COG4529	Protein conserved in bacteria
E3162_RS12730	COG3468	outer membrane autotransporter barrel domain protein
E3162_RS12740	COG0307	riboflavin synthase, alpha
E3162_RS12750	COG2814	Major facilitator Superfamily
E3162_RS12755	COG0583	DNA-binding transcription factor activity
E3162_RS12770	COG2814	Major facilitator Superfamily
E3162_RS12775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E3162_RS12780	COG0791	NLP P60 protein
E3162_RS12785	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E3162_RS12790	COG1201	RNA secondary structure unwinding
E3162_RS12800	COG0346	lactoylglutathione lyase activity
E3162_RS12805	COG1902	pentaerythritol trinitrate reductase activity
E3162_RS12810	COG1309	transcriptional regulator
E3162_RS12815	COG3313	Fe-S protein
E3162_RS12825	COG2032	superoxide dismutase activity
E3162_RS12830	COG1289	transmembrane transporter activity
E3162_RS12835	COG1566	PFAM secretion protein HlyD family protein
E3162_RS12850	COG3133	Outer membrane lipoprotein
E3162_RS12860	COG3895	Periplasmic Protein
E3162_RS12875	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
E3162_RS12880	COG0625	glutathione transferase activity
E3162_RS12885	COG3104	oligopeptide transport
E3162_RS12890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3162_RS12900	COG4659	FMN binding
E3162_RS12940	COG0673	inositol 2-dehydrogenase activity
E3162_RS12950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E3162_RS12955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3162_RS12955	COG1263	PTS System
E3162_RS12960	COG1609	Transcriptional regulator
E3162_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS12970	COG1309	transcriptional regulator
E3162_RS12990	COG5339	Protein conserved in bacteria
E3162_RS12995	COG1482	cell wall glycoprotein biosynthetic process
E3162_RS13000	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3162_RS13000	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3162_RS13005	COG0114	fumarate hydratase activity
E3162_RS13015	COG2205	protein histidine kinase activity
E3162_RS13020	COG0745	RESPONSE REGULATOR receiver
E3162_RS13025	COG3136	membrane protein required for alginate biosynthesis
E3162_RS13035	COG0531	amino acid
E3162_RS13045	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E3162_RS13050	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E3162_RS13055	COG0628	permease
E3162_RS13070	COG3591	Belongs to the peptidase S1B family
E3162_RS13085	COG2814	Major facilitator Superfamily
E3162_RS13090	COG0583	DNA-binding transcription factor activity
E3162_RS13095	COG1940	carbohydrate kinase activity
E3162_RS13100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3162_RS13110	COG3381	protein complex oligomerization
E3162_RS13115	COG3302	dmso reductase anchor subunit
E3162_RS13120	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS13125	COG0243	molybdopterin cofactor binding
E3162_RS13130	COG0243	molybdopterin cofactor binding
E3162_RS13145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3162_RS13170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3162_RS13225	COG1846	Transcriptional regulator
E3162_RS13230	COG1484	DNA-dependent DNA replication
E3162_RS13265	COG1403	HNH endonuclease
E3162_RS13270	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3162_RS13320	COG3772	lysozyme
E3162_RS13450	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS13470	COG0589	response to stress
E3162_RS13480	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3162_RS13480	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3162_RS13480	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3162_RS13480	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3162_RS13485	COG3042	response to heat
E3162_RS13490	COG3187	Heat shock protein
E3162_RS13495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E3162_RS13500	COG2911	Protein conserved in bacteria
E3162_RS13510	COG3784	Protein of unknown function (DUF1318)
E3162_RS13525	COG0667	Aldo Keto reductase
E3162_RS13535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E3162_RS13540	COG4589	Belongs to the CDS family
E3162_RS13545	COG2267	carboxylic ester hydrolase activity
E3162_RS13550	COG2453	phosphatase
E3162_RS13550	COG0671	phosphoesterase, PA-phosphatase related
E3162_RS13555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
E3162_RS13560	COG1643	Atp-dependent helicase
E3162_RS13585	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E3162_RS13590	COG1012	belongs to the aldehyde dehydrogenase family
E3162_RS13595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E3162_RS13600	COG3038	cytochrome b561
E3162_RS13615	COG0840	transmembrane signaling receptor activity
E3162_RS13620	COG0583	DNA-binding transcription factor activity
E3162_RS13625	COG5383	Protein conserved in bacteria
E3162_RS13635	COG2841	Protein conserved in bacteria
E3162_RS13645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E3162_RS13650	COG1275	C4-dicarboxylate transporter malic acid transport protein
E3162_RS13655	COG0500	methyltransferase
E3162_RS13665	COG3135	benzoate transporter
E3162_RS13670	COG1396	sequence-specific DNA binding
E3162_RS13675	COG0826	peptidase U32
E3162_RS13685	COG1724	mRNA binding
E3162_RS13690	COG1598	PFAM Uncharacterised protein family UPF0150
E3162_RS13695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3162_RS13700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3162_RS13705	COG3842	ATPase activity
E3162_RS13710	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3162_RS13715	COG1177	transmembrane transport
E3162_RS13740	COG3238	Protein conserved in bacteria
E3162_RS13745	COG1247	-acetyltransferase
E3162_RS13750	COG2130	NADP-dependent
E3162_RS13755	COG1802	Transcriptional regulator
E3162_RS13760	COG4772	TonB-dependent receptor
E3162_RS13765	COG3391	amine dehydrogenase activity
E3162_RS13770	COG1113	amino acid transport
E3162_RS13775	COG0625	glutathione transferase activity
E3162_RS13785	COG3501	Rhs element vgr protein
E3162_RS13790	COG3209	COG3209 Rhs family protein
E3162_RS13820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3162_RS13830	COG0384	phenazine biosynthesis protein PhzF
E3162_RS13835	COG2181	nitrate reductase activity
E3162_RS13840	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E3162_RS13845	COG1140	nitrate reductase beta subunit
E3162_RS13850	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3162_RS13855	COG2223	nitrite transmembrane transporter activity
E3162_RS13860	COG4886	Leucine-rich repeat (LRR) protein
E3162_RS13865	COG4886	Leucine-rich repeat (LRR) protein
E3162_RS13880	COG0697	spore germination
E3162_RS13890	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS13895	COG2864	formate dehydrogenase
E3162_RS13900	COG3093	addiction module antidote protein HigA
E3162_RS13905	COG1064	alcohol dehydrogenase
E3162_RS13925	COG1764	response to oxidative stress
E3162_RS13930	COG4608	Belongs to the ABC transporter superfamily
E3162_RS13935	COG0444	Belongs to the ABC transporter superfamily
E3162_RS13940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3162_RS13945	COG0601	transmembrane transport
E3162_RS13950	COG0747	negative chemotaxis
E3162_RS13955	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E3162_RS13975	COG0531	amino acid
E3162_RS13980	COG0076	glutamate decarboxylase activity
E3162_RS13985	COG0612	Peptidase, M16
E3162_RS13990	COG4771	TonB-dependent receptor
E3162_RS13995	COG4178	(ABC) transporter
E3162_RS14005	COG0641	radical SAM
E3162_RS14010	COG3119	arylsulfatase activity
E3162_RS14015	COG2207	Transcriptional regulator
E3162_RS14025	COG0243	molybdopterin cofactor binding
E3162_RS14030	COG3539	Fimbrial protein
E3162_RS14035	COG3539	Fimbrial protein
E3162_RS14040	COG3539	Fimbrial protein
E3162_RS14045	COG3188	usher protein
E3162_RS14055	COG3539	Fimbrial protein
E3162_RS14075	COG3210	domain, Protein
E3162_RS14075	COG2911	Protein conserved in bacteria
E3162_RS14080	COG1070	Carbohydrate kinase
E3162_RS14090	COG1129	ABC transporter
E3162_RS14095	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3162_RS14100	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3162_RS14110	COG1830	Aldolase
E3162_RS14125	COG3781	membrane
E3162_RS14135	COG2199	diguanylate cyclase activity
E3162_RS14145	COG2066	Belongs to the glutaminase family
E3162_RS14150	COG1012	belongs to the aldehyde dehydrogenase family
E3162_RS14155	COG0583	DNA-binding transcription factor activity
E3162_RS14170	COG2814	Major facilitator Superfamily
E3162_RS14175	COG2095	MarC family integral membrane protein
E3162_RS14180	COG1846	Transcriptional regulator
E3162_RS14185	COG4977	sequence-specific DNA binding
E3162_RS14195	COG0697	spore germination
E3162_RS14200	COG2814	Major facilitator Superfamily
E3162_RS14220	COG3706	GGDEF domain
E3162_RS14225	COG3111	PFAM Bacterial OB fold (BOF) protein
E3162_RS14230	COG1546	Belongs to the CinA family
E3162_RS14235	COG0339	signal peptide processing
E3162_RS14240	COG4221	oxidoreductase activity
E3162_RS14245	COG1802	Transcriptional regulator
E3162_RS14255	COG0246	Mannitol dehydrogenase
E3162_RS14260	COG0477	Major facilitator Superfamily
E3162_RS14290	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS14375	COG1030	water channel activity
E3162_RS14395	COG4220	transposase activity
E3162_RS14410	COG5562	phage envelope protein
E3162_RS14445	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3162_RS14465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E3162_RS14475	COG2076	Multidrug Resistance protein
E3162_RS14500	COG0582	viral genome integration into host DNA
E3162_RS14505	COG0538	isocitrate dehydrogenase activity
E3162_RS14510	COG1187	pseudouridine synthase activity
E3162_RS14520	COG0482	sulfurtransferase activity
E3162_RS14530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E3162_RS14535	COG0745	RESPONSE REGULATOR receiver
E3162_RS14540	COG2205	protein histidine kinase activity
E3162_RS14550	COG4626	Terminase
E3162_RS14550	COG1802	Transcriptional regulator
E3162_RS14670	COG2850	peptidyl-arginine hydroxylation
E3162_RS14680	COG3842	ATPase activity
E3162_RS14865	COG3772	lysozyme
E3162_RS14985	COG1846	Transcriptional regulator
E3162_RS14990	COG1484	DNA-dependent DNA replication
E3162_RS14995	COG3756	Protein conserved in bacteria
E3162_RS15030	COG3646	Phage regulatory protein
E3162_RS15050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3162_RS15055	COG3723	Recombinational DNA repair protein, rece pathway
E3162_RS15075	COG0582	viral genome integration into host DNA
E3162_RS15085	COG0513	Belongs to the DEAD box helicase family
E3162_RS15100	COG3706	GGDEF domain
E3162_RS15105	COG2840	Smr protein MutS2
E3162_RS15110	COG0583	DNA-binding transcription factor activity
E3162_RS15115	COG1473	amidohydrolase
E3162_RS15120	COG1473	amidohydrolase
E3162_RS15125	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3162_RS15130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3162_RS15135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3162_RS15140	COG0589	response to stress
E3162_RS15145	COG3182	Iron-regulated membrane protein
E3162_RS15150	COG0668	transmembrane transport
E3162_RS15155	COG4166	transmembrane transport
E3162_RS15160	COG0583	DNA-binding transcription factor activity
E3162_RS15165	COG1073	alpha beta
E3162_RS15170	COG1073	alpha beta
E3162_RS15175	COG1073	alpha beta
E3162_RS15180	COG0702	epimerase
E3162_RS15185	COG2866	Carboxypeptidase
E3162_RS15190	COG4948	Mandelate Racemase Muconate Lactonizing
E3162_RS15195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E3162_RS15200	COG3283	Transcriptional regulator of aromatic amino acids metabolism
E3162_RS15210	COG3106	COG3106 Predicted ATPase
E3162_RS15215	COG1609	Transcriptional regulator
E3162_RS15225	COG3842	ATPase activity
E3162_RS15230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3162_RS15240	COG0673	inositol 2-dehydrogenase activity
E3162_RS15245	COG1082	Xylose isomerase domain protein TIM barrel
E3162_RS15250	COG1063	alcohol dehydrogenase
E3162_RS15255	COG0395	ABC-type sugar transport system, permease component
E3162_RS15260	COG1175	transmembrane transport
E3162_RS15275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3162_RS15285	COG1983	PspC domain protein
E3162_RS15295	COG1842	Phage shock protein A
E3162_RS15300	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E3162_RS15305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3162_RS15310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E3162_RS15315	COG1012	belongs to the aldehyde dehydrogenase family
E3162_RS15320	COG1396	sequence-specific DNA binding
E3162_RS15320	COG1917	Cupin 2, conserved barrel domain protein
E3162_RS15325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
E3162_RS15330	COG0174	glutamine synthetase
E3162_RS15340	COG0531	amino acid
E3162_RS15350	COG4166	transmembrane transport
E3162_RS15355	COG4168	peptide transport system, permease
E3162_RS15360	COG4171	peptide transport system, permease
E3162_RS15365	COG4172	Belongs to the ABC transporter superfamily
E3162_RS15370	COG4172	Belongs to the ABC transporter superfamily
E3162_RS15375	COG2814	Major facilitator Superfamily
E3162_RS15390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3162_RS15400	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E3162_RS15405	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3162_RS15405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3162_RS15415	COG5001	Diguanylate cyclase
E3162_RS15425	COG1349	DNA-binding transcription factor activity
E3162_RS15435	COG0023	Translation Initiation Factor
E3162_RS15445	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E3162_RS15450	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E3162_RS15455	COG0671	phosphoesterase, PA-phosphatase related
E3162_RS15465	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E3162_RS15485	COG0583	DNA-binding transcription factor activity
E3162_RS15490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E3162_RS15500	COG0616	signal peptide processing
E3162_RS15505	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS15510	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
E3162_RS15515	COG1187	pseudouridine synthase activity
E3162_RS15520	COG4907	membrane protein (DUF2207)
E3162_RS15525	COG0009	L-threonylcarbamoyladenylate synthase
E3162_RS15530	COG0613	PHP domain protein
E3162_RS15540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3162_RS15545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3162_RS15545	COG0512	Glutamine amidotransferase of anthranilate synthase
E3162_RS15550	COG0134	indole-3-glycerol-phosphate synthase activity
E3162_RS15550	COG0135	phosphoribosylanthranilate isomerase activity
E3162_RS15565	COG3729	General stress protein
E3162_RS15570	COG3685	Protein conserved in bacteria
E3162_RS15575	COG3685	Protein conserved in bacteria
E3162_RS15625	COG3436	PFAM IS66 Orf2 family protein
E3162_RS15630	COG4372	Transposase
E3162_RS15675	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS15810	COG3772	lysozyme
E3162_RS15855	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3162_RS15860	COG1403	HNH endonuclease
E3162_RS15890	COG1846	Transcriptional regulator
E3162_RS15915	COG1396	sequence-specific DNA binding
E3162_RS15955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3162_RS15965	COG0582	viral genome integration into host DNA
E3162_RS15970	COG3047	cAMP biosynthetic process
E3162_RS15990	COG1607	acyl-coa hydrolase
E3162_RS15995	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
E3162_RS16000	COG2350	Protein conserved in bacteria
E3162_RS16005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E3162_RS16025	COG4608	Belongs to the ABC transporter superfamily
E3162_RS16030	COG0444	Belongs to the ABC transporter superfamily
E3162_RS16035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3162_RS16040	COG0601	transmembrane transport
E3162_RS16045	COG4166	transmembrane transport
E3162_RS16050	COG2095	MarC family integral membrane protein
E3162_RS16055	COG1012	belongs to the aldehyde dehydrogenase family
E3162_RS16055	COG1454	alcohol dehydrogenase
E3162_RS16060	COG1435	thymidine kinase activity
E3162_RS16070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E3162_RS16075	COG0745	RESPONSE REGULATOR receiver
E3162_RS16080	COG1752	Esterase of the alpha-beta hydrolase superfamily
E3162_RS16090	COG0788	formyltetrahydrofolate deformylase activity
E3162_RS16125	COG2181	nitrate reductase activity
E3162_RS16130	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E3162_RS16135	COG1140	nitrate reductase beta subunit
E3162_RS16140	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3162_RS16145	COG2223	nitrite transmembrane transporter activity
E3162_RS16150	COG3850	Histidine kinase
E3162_RS16155	COG2197	response regulator
E3162_RS16160	COG4932	domain protein
E3162_RS16165	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E3162_RS16170	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
E3162_RS16175	COG4572	Cation transport regulator
E3162_RS16180	COG0387	Pfam Sodium calcium exchanger
E3162_RS16200	COG2912	Transglutaminase-like superfamily
E3162_RS16205	COG3094	Invasion gene expression up-regulator, SirB
E3162_RS16235	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E3162_RS16240	COG0659	secondary active sulfate transmembrane transporter activity
E3162_RS16255	COG0012	GTP binding
E3162_RS16260	COG3468	outer membrane autotransporter barrel domain protein
E3162_RS16265	COG3284	Transcriptional regulator
E3162_RS16270	COG2376	Dihydroxyacetone kinase
E3162_RS16275	COG1461	Dihydroxyacetone kinase
E3162_RS16280	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
E3162_RS16280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS16280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3162_RS16305	COG1120	ATPase activity
E3162_RS16315	COG0157	Belongs to the NadC ModD family
E3162_RS16350	COG1619	proteins homologs of microcin C7 resistance protein MccF
E3162_RS16365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E3162_RS16375	COG2719	SpoVR family
E3162_RS16390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
E3162_RS16395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3162_RS16400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E3162_RS16415	COG0179	Fumarylacetoacetate (FAA) hydrolase
E3162_RS16445	COG2894	cell division
E3162_RS16470	COG4571	Outer membrane protease
E3162_RS16480	COG4372	Transposase
E3162_RS16485	COG3436	PFAM IS66 Orf2 family protein
E3162_RS16500	COG0500	methyltransferase
E3162_RS16505	COG3729	General stress protein
E3162_RS16510	COG3685	Protein conserved in bacteria
E3162_RS16515	COG3685	Protein conserved in bacteria
E3162_RS16520	COG3546	catalase activity
E3162_RS16525	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E3162_RS16530	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS16580	COG1196	nuclear chromosome segregation
E3162_RS16630	COG1030	water channel activity
E3162_RS16650	COG4220	transposase activity
E3162_RS16680	COG3772	lysozyme
E3162_RS16720	COG2207	Transcriptional regulator
E3162_RS16735	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3162_RS16740	COG1403	HNH endonuclease
E3162_RS16750	COG3111	PFAM Bacterial OB fold (BOF) protein
E3162_RS16785	COG1846	Transcriptional regulator
E3162_RS16820	COG3436	PFAM IS66 Orf2 family protein
E3162_RS16825	COG4372	Transposase
E3162_RS16850	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS16980	COG3772	lysozyme
E3162_RS17020	COG0484	heat shock protein binding
E3162_RS17025	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3162_RS17030	COG1403	HNH endonuclease
E3162_RS17085	COG1846	Transcriptional regulator
E3162_RS17105	COG4197	protein conserved in bacteria, prophage-related
E3162_RS17135	COG0582	viral genome integration into host DNA
E3162_RS17140	COG1177	transmembrane transport
E3162_RS17145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3162_RS17150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E3162_RS17160	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3162_RS17165	COG1136	(ABC) transporter
E3162_RS17170	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3162_RS17175	COG4763	Acyl-transferase
E3162_RS17180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E3162_RS17185	COG1388	LysM domain
E3162_RS17185	COG1376	ErfK ybiS ycfS ynhG family protein
E3162_RS17195	COG1309	transcriptional regulator
E3162_RS17200	COG3134	Outer membrane lipoprotein
E3162_RS17205	COG1252	NADH dehydrogenase
E3162_RS17220	COG0510	thiamine kinase activity
E3162_RS17225	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
E3162_RS17230	COG5633	Lipoprotein
E3162_RS17235	COG0537	adenosine 5'-monophosphoramidase activity
E3162_RS17245	COG4773	Receptor
E3162_RS17250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3162_RS17250	COG1263	PTS System
E3162_RS17255	COG0084	hydrolase, TatD family'
E3162_RS17260	COG0470	DNA polymerase III
E3162_RS17270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E3162_RS17275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E3162_RS17280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3162_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS17295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E3162_RS17315	COG1399	metal-binding, possibly nucleic acid-binding protein
E3162_RS17320	COG0424	maF-like protein
E3162_RS17325	COG0564	pseudouridine synthase activity
E3162_RS17330	COG1530	ribonuclease E activity
E3162_RS17335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E3162_RS17345	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3162_RS17345	COG3951	Flagellar rod assembly protein muramidase FlgJ
E3162_RS17360	COG4786	Flagellar basal body rod
E3162_RS17370	COG1749	Flagellar hook protein flgE
E3162_RS17375	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
E3162_RS17380	COG1558	bacterial-type flagellum-dependent cell motility
E3162_RS17385	COG1815	bacterial-type flagellum-dependent cell motility
E3162_RS17390	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
E3162_RS17395	COG2747	anti-sigma28 factor FlgM
E3162_RS17400	COG3418	PFAM FlgN family protein
E3162_RS17405	COG0728	peptidoglycan biosynthetic process
E3162_RS17410	COG0673	inositol 2-dehydrogenase activity
E3162_RS17420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3162_RS17430	COG2999	glutathione oxidoreductase activity
E3162_RS17465	COG3038	cytochrome b561
E3162_RS17470	COG2353	YceI-like domain
E3162_RS17480	COG1560	Kdo2-lipid A biosynthetic process
E3162_RS17495	COG5645	(Lipo)protein
E3162_RS17500	COG2943	transferase activity, transferring hexosyl groups
E3162_RS17515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3162_RS17520	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E3162_RS17545	COG2197	response regulator
E3162_RS17560	COG1462	curli production assembly transport component CsgG
E3162_RS17570	COG3381	protein complex oligomerization
E3162_RS17620	COG2003	Belongs to the UPF0758 family
E3162_RS17650	COG3468	outer membrane autotransporter barrel domain protein
E3162_RS17695	COG1475	DNA binding
E3162_RS17700	COG3969	phosphoadenosine phosphosulfate
E3162_RS17705	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E3162_RS17715	COG2831	hemolysin activation secretion protein
E3162_RS17775	COG4771	TonB-dependent receptor
E3162_RS17835	COG1358	cellular component organization or biogenesis
E3162_RS17870	COG4372	Transposase
E3162_RS17875	COG3436	PFAM IS66 Orf2 family protein
E3162_RS17900	COG0254	rRNA binding
E3162_RS17945	COG0829	nickel cation binding
E3162_RS17955	COG2194	sulfuric ester hydrolase activity
E3162_RS17960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E3162_RS17995	COG3436	PFAM IS66 Orf2 family protein
E3162_RS18000	COG4372	Transposase
E3162_RS18025	COG4983	Phage plasmid primase, P4 family domain protein
E3162_RS18050	COG0582	viral genome integration into host DNA
E3162_RS18100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3162_RS18105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
E3162_RS18115	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E3162_RS18125	COG0736	holo-[acyl-carrier-protein] synthase activity
E3162_RS18130	COG2831	hemolysin activation secretion protein
E3162_RS18135	COG3210	domain, Protein
E3162_RS18145	COG3539	Fimbrial protein
E3162_RS18155	COG3188	usher protein
E3162_RS18165	COG3121	Chaperone
E3162_RS18170	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS18175	COG3710	Transcriptional regulator
E3162_RS18185	COG2200	EAL domain
E3162_RS18190	COG3706	GGDEF domain
E3162_RS18195	COG0457	Tetratricopeptide repeat
E3162_RS18200	COG0726	polysaccharide deacetylase
E3162_RS18200	COG1649	PFAM Uncharacterised BCR, COG1649
E3162_RS18205	COG1215	transferase activity, transferring glycosyl groups
E3162_RS18210	COG3658	cytochrome
E3162_RS18215	COG1702	phosphate starvation-inducible protein PhoH
E3162_RS18220	COG2837	iron assimilation
E3162_RS18225	COG2822	iron ion transport
E3162_RS18240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3162_RS18250	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E3162_RS18250	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E3162_RS18250	COG0506	proline dehydrogenase activity
E3162_RS18255	COG1309	transcriptional regulator
E3162_RS18290	COG2233	PERMEase
E3162_RS18295	COG3729	General stress protein
E3162_RS18335	COG0243	molybdopterin cofactor binding
E3162_RS18340	COG3005	denitrification pathway
E3162_RS18345	COG0745	RESPONSE REGULATOR receiver
E3162_RS18350	COG1879	ABC-type sugar transport system periplasmic component
E3162_RS18355	COG0784	Response regulator, receiver
E3162_RS18355	COG2205	protein histidine kinase activity
E3162_RS18355	COG2198	Histidine kinase
E3162_RS18360	COG0348	domain, Protein
E3162_RS18380	COG1278	Cold shock
E3162_RS18385	COG1278	Cold shock
E3162_RS18405	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3162_RS18410	COG1596	polysaccharide export
E3162_RS18415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E3162_RS18420	COG0489	protein tyrosine kinase activity
E3162_RS18420	COG3206	protein involved in exopolysaccharide biosynthesis
E3162_RS18435	COG1294	oxidase, subunit
E3162_RS18440	COG1271	oxidase subunit
E3162_RS18445	COG1773	rubredoxin
E3162_RS18450	COG1999	signal sequence binding
E3162_RS18455	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3162_RS18460	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E3162_RS18465	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E3162_RS18470	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3162_RS18490	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS18505	COG2032	superoxide dismutase activity
E3162_RS18585	COG4220	transposase activity
E3162_RS18600	COG3772	lysozyme
E3162_RS18650	COG2207	Transcriptional regulator
E3162_RS18670	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E3162_RS18675	COG1403	HNH endonuclease
E3162_RS18705	COG1846	Transcriptional regulator
E3162_RS18710	COG1484	DNA-dependent DNA replication
E3162_RS18775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3162_RS18790	COG0670	Belongs to the BI1 family
E3162_RS18795	COG2920	part of a sulfur-relay system
E3162_RS18800	COG1254	Belongs to the acylphosphatase family
E3162_RS18815	COG1832	CoA-binding protein
E3162_RS18830	COG0210	DNA helicase
E3162_RS18835	COG3304	Inner membrane component domain
E3162_RS18840	COG1289	transmembrane transporter activity
E3162_RS18845	COG3070	regulator of competence-specific genes
E3162_RS18855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E3162_RS18855	COG2885	chlorophyll binding
E3162_RS18865	COG1067	ATP-dependent peptidase activity
E3162_RS18875	COG3130	regulation of translation
E3162_RS18880	COG3009	Protein conserved in bacteria
E3162_RS18885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3162_RS18885	COG3008	intermembrane lipid transfer
E3162_RS18890	COG2995	paraquat-inducible protein a
E3162_RS18895	COG0488	(ABC) transporter
E3162_RS18905	COG3217	Mosc domain protein beta barrel domain protein
E3162_RS18905	COG0633	Ferredoxin
E3162_RS18925	COG3539	Fimbrial protein
E3162_RS18930	COG3539	Fimbrial protein
E3162_RS18935	COG3539	Fimbrial protein
E3162_RS18945	COG3121	Chaperone
E3162_RS18950	COG3539	Fimbrial protein
E3162_RS18955	COG0431	NADPH-dependent FMN reductase
E3162_RS18960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E3162_RS18970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3162_RS18975	COG1116	anion transmembrane transporter activity
E3162_RS18980	COG0308	aminopeptidase N
E3162_RS18990	COG0017	Asparaginyl-tRNA synthetase
E3162_RS18995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3162_RS19000	COG1448	Aminotransferase
E3162_RS19005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3162_RS19010	COG3108	Peptidase M15
E3162_RS19015	COG2989	Protein conserved in bacteria
E3162_RS19025	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E3162_RS19035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3162_RS19040	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E3162_RS19045	COG3173	Aminoglycoside phosphotransferase
E3162_RS19060	COG3214	Protein conserved in bacteria
E3162_RS19070	COG1132	(ABC) transporter
E3162_RS19085	COG0539	negative regulation of cytoplasmic translation
E3162_RS19095	COG0501	Belongs to the peptidase M48B family
E3162_RS19110	COG2323	membrane
E3162_RS19115	COG1944	ATP diphosphatase activity
E3162_RS19120	COG2116	formate transmembrane transporter activity
E3162_RS19125	COG1882	Formate acetyltransferase
E3162_RS19130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3162_RS19140	COG0531	amino acid
E3162_RS19150	COG1335	isochorismatase
E3162_RS19155	COG3302	dmso reductase anchor subunit
E3162_RS19160	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS19165	COG0243	molybdopterin cofactor binding
E3162_RS19175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3162_RS19185	COG1674	ftsk spoiiie
E3162_RS19185	COG1178	ABC-type Fe3 transport system permease component
E3162_RS19190	COG1522	sequence-specific DNA binding
E3162_RS19195	COG0492	ferredoxin-NADP+ reductase activity
E3162_RS19200	COG4988	ABC transporter
E3162_RS19205	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3162_RS19225	COG0542	response to heat
E3162_RS19310	COG1278	Cold shock
E3162_RS19315	COG1136	(ABC) transporter
E3162_RS19315	COG0577	efflux transmembrane transporter activity
E3162_RS19320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3162_RS19325	COG2990	Protein conserved in bacteria
E3162_RS19330	COG3593	DNA synthesis involved in DNA repair
E3162_RS19335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3162_RS19340	COG2431	L-lysine efflux transmembrane transporter activity
E3162_RS19350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3162_RS19355	COG0028	Belongs to the TPP enzyme family
E3162_RS19360	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E3162_RS19365	COG0702	epimerase
E3162_RS19370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3162_RS19375	COG3023	N-Acetylmuramoyl-L-alanine amidase
E3162_RS19395	COG1126	abc transporter atp-binding protein
E3162_RS19400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3162_RS19405	COG4215	(ABC) transporter
E3162_RS19410	COG4160	amino acid transport
E3162_RS19415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3162_RS19445	COG1177	transmembrane transport
E3162_RS19450	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3162_RS19455	COG3842	ATPase activity
E3162_RS19460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3162_RS19475	COG0778	Nitroreductase
E3162_RS19485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3162_RS19500	COG3226	Transcriptional regulator
E3162_RS19505	COG0738	Major facilitator superfamily
E3162_RS19510	COG0561	phosphatase activity
E3162_RS19525	COG0671	phosphoesterase, PA-phosphatase related
E3162_RS19530	COG1349	DNA-binding transcription factor activity
E3162_RS19535	COG1686	Belongs to the peptidase S11 family
E3162_RS19540	COG0625	glutathione transferase activity
E3162_RS19545	COG2133	pyrroloquinoline quinone binding
E3162_RS19570	COG2199	diguanylate cyclase activity
E3162_RS19575	COG2200	EAL domain
E3162_RS19585	COG0601	transmembrane transport
E3162_RS19590	COG0747	negative chemotaxis
E3162_RS19595	COG4172	Belongs to the ABC transporter superfamily
E3162_RS19605	COG0303	'Molybdopterin
E3162_RS19610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3162_RS19615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3162_RS19620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3162_RS19630	COG0561	phosphatase activity
E3162_RS19640	COG0488	(ABC) transporter
E3162_RS19645	COG1376	ErfK ybiS ycfS ynhG family protein
E3162_RS19650	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E3162_RS19655	COG1321	iron dependent repressor
E3162_RS19665	COG2194	sulfuric ester hydrolase activity
E3162_RS19670	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E3162_RS19680	COG5006	permease, DMT superfamily
E3162_RS19690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3162_RS19695	COG0765	amino acid transport
E3162_RS19700	COG1126	abc transporter atp-binding protein
E3162_RS19705	COG0668	transmembrane transport
E3162_RS19720	COG4774	siderophore transport
E3162_RS19730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3162_RS19740	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E3162_RS19745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3162_RS19750	COG1199	ATP-dependent helicase activity
E3162_RS19760	COG0513	Belongs to the DEAD box helicase family
E3162_RS19765	COG1309	transcriptional regulator
E3162_RS19775	COG1131	(ABC) transporter
E3162_RS19780	COG0842	Transport permease protein
E3162_RS19785	COG0842	Transport permease protein
E3162_RS19795	COG3568	Endonuclease Exonuclease Phosphatase
E3162_RS19800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3162_RS19805	COG0392	lysyltransferase activity
E3162_RS19810	COG0670	Belongs to the BI1 family
E3162_RS19815	COG0670	Belongs to the BI1 family
E3162_RS19820	COG0314	molybdopterin synthase activity
E3162_RS19825	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E3162_RS19835	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3162_RS19845	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3162_RS19855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3162_RS19860	COG2226	methyltransferase
E3162_RS19875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3162_RS19880	COG1881	PFAM PEBP family protein
E3162_RS19995	COG0740	serine-type endopeptidase activity
E3162_RS20035	COG3772	lysozyme
E3162_RS20150	COG0582	viral genome integration into host DNA
E3162_RS20155	COG4677	pectinesterase activity
E3162_RS20160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E3162_RS20165	COG0471	metal ion transport
E3162_RS20170	COG2828	Protein conserved in bacteria
E3162_RS20175	COG0583	DNA-binding transcription factor activity
E3162_RS20185	COG0561	phosphatase activity
E3162_RS20195	COG4149	molybdate abc transporter
E3162_RS20200	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3162_RS20210	COG2005	Transcriptional regulator
E3162_RS20210	COG3585	molybdate ion transport
E3162_RS20215	COG1119	ATPase activity
E3162_RS20220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E3162_RS20225	COG1085	galactose-1-phosphate uridylyltransferase
E3162_RS20235	COG2017	converts alpha-aldose to the beta-anomer
E3162_RS20245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E3162_RS20255	COG1230	cation diffusion facilitator family transporter
E3162_RS20260	COG3201	nicotinamide mononucleotide transporter
E3162_RS20265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
E3162_RS20300	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E3162_RS20305	COG2885	chlorophyll binding
E3162_RS20315	COG3064	Membrane
E3162_RS20320	COG0848	biopolymer transport protein
E3162_RS20325	COG0811	peptide transport
E3162_RS20330	COG0824	Thioesterase
E3162_RS20335	COG3790	cyd operon protein YbgE
E3162_RS20340	COG4890	Cyd operon protein YbgT
E3162_RS20345	COG1294	oxidase, subunit
E3162_RS20350	COG1271	oxidase subunit
E3162_RS20365	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E3162_RS20375	COG4865	methylaspartate mutase activity
E3162_RS20380	COG3799	methylaspartate ammonia-lyase activity
E3162_RS20395	COG1301	dicarboxylic acid transport
E3162_RS20400	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3162_RS20400	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3162_RS20405	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
E3162_RS20410	COG0583	DNA-binding transcription factor activity
E3162_RS20415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3162_RS20425	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3162_RS20430	COG0567	Dehydrogenase, E1 component
E3162_RS20435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3162_RS20440	COG1053	succinate dehydrogenase
E3162_RS20445	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E3162_RS20450	COG2009	succinate dehydrogenase
E3162_RS20460	COG0372	Belongs to the citrate synthase family
E3162_RS20465	COG3539	Fimbrial protein
E3162_RS20470	COG3188	usher protein
E3162_RS20475	COG3121	Chaperone
E3162_RS20480	COG3539	Fimbrial protein
E3162_RS20485	COG3180	Ammonia monooxygenase
E3162_RS20490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3162_RS20500	COG1984	allophanate hydrolase subunit 2
E3162_RS20505	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3162_RS20510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E3162_RS20515	COG3104	oligopeptide transport
E3162_RS20520	COG0415	Belongs to the DNA photolyase family
E3162_RS20525	COG3272	Protein of unknown function (DUF1722)
E3162_RS20530	COG5433	transposase activity
E3162_RS20545	COG3209	COG3209 Rhs family protein
E3162_RS20575	COG2205	protein histidine kinase activity
E3162_RS20580	COG0745	RESPONSE REGULATOR receiver
E3162_RS20590	COG1982	Orn Lys Arg decarboxylase major
E3162_RS20595	COG0531	amino acid
E3162_RS20600	COG0033	Phosphoglucomutase
E3162_RS20605	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
E3162_RS20610	COG0596	Alpha beta hydrolase
E3162_RS20620	COG0716	FMN binding
E3162_RS20630	COG0735	belongs to the Fur family
E3162_RS20650	COG2190	(PTS) system
E3162_RS20650	COG1263	PTS System
E3162_RS20650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3162_RS20660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3162_RS20665	COG1846	Transcriptional regulator
E3162_RS20665	COG1940	carbohydrate kinase activity
E3162_RS20670	COG0647	UMP catabolic process
E3162_RS20675	COG0367	asparagine synthase
E3162_RS20715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3162_RS20725	COG1702	phosphate starvation-inducible protein PhoH
E3162_RS20735	COG4535	Mg2 and Co2 transporter CorC
E3162_RS20740	COG0815	Transfers the fatty acyl group on membrane lipoproteins
E3162_RS20745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3162_RS20750	COG0765	amino acid transport
E3162_RS20755	COG0765	amino acid transport
E3162_RS20760	COG1126	abc transporter atp-binding protein
E3162_RS20770	COG0443	Heat shock 70 kDa protein
E3162_RS20785	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E3162_RS20790	COG2214	Heat shock protein DnaJ domain protein
E3162_RS20805	COG2888	peptidyl-tyrosine sulfation
E3162_RS20820	COG1466	dna polymerase III delta subunit
E3162_RS20830	COG0406	alpha-ribazole phosphatase activity
E3162_RS20835	COG0799	negative regulation of ribosome biogenesis
E3162_RS20845	COG0768	penicillin binding
E3162_RS20850	COG0772	Belongs to the SEDS family
E3162_RS20855	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3162_RS20860	COG1686	Belongs to the peptidase S11 family
E3162_RS20875	COG0583	DNA-binding transcription factor activity
E3162_RS20885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3162_RS20890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3162_RS20910	COG3069	C4-dicarboxylate transmembrane transporter activity
E3162_RS20915	COG4565	transcriptional regulatory protein
E3162_RS20920	COG3290	protein histidine kinase activity
E3162_RS20925	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E3162_RS20935	COG2301	Belongs to the HpcH HpaI aldolase family
E3162_RS20940	COG3051	citrate lyase alpha subunit
E3162_RS20950	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
E3162_RS20955	COG0471	metal ion transport
E3162_RS20960	COG3719	Belongs to the RNase T2 family
E3162_RS20965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3162_RS20970	COG1063	alcohol dehydrogenase
E3162_RS20975	COG0589	response to stress
E3162_RS20980	COG3634	alkyl hydroperoxide reductase activity
E3162_RS20985	COG0450	alkyl hydroperoxide reductase
E3162_RS20990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3162_RS20995	COG0583	DNA-binding transcription factor activity
E3162_RS21000	COG3969	phosphoadenosine phosphosulfate
E3162_RS21005	COG1475	DNA binding
E3162_RS21010	COG0436	Aminotransferase
E3162_RS21015	COG0371	Dehydrogenase
E3162_RS21020	COG2879	small protein
E3162_RS21025	COG1966	Carbon starvation protein
E3162_RS21035	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS21040	COG1535	isochorismatase
E3162_RS21040	COG3433	isochorismatase activity
E3162_RS21045	COG1021	2,3-dihydroxybenzoate-AMP ligase
E3162_RS21050	COG1169	isochorismate synthase
E3162_RS21055	COG4592	Periplasmic binding protein
E3162_RS21065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3162_RS21070	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3162_RS21075	COG1120	ATPase activity
E3162_RS21080	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E3162_RS21085	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E3162_RS21085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E3162_RS21090	COG3251	PFAM MbtH domain protein
E3162_RS21095	COG2382	esterase
E3162_RS21100	COG4771	TonB-dependent receptor
E3162_RS21105	COG2977	Belongs to the P-Pant transferase superfamily
E3162_RS21130	COG2315	Protein conserved in bacteria
E3162_RS21135	COG0778	Nitroreductase
E3162_RS21140	COG0668	transmembrane transport
E3162_RS21145	COG1113	amino acid transport
E3162_RS21150	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3162_RS21155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3162_RS21160	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3162_RS21165	COG1538	Outer membrane efflux protein
E3162_RS21170	COG0745	RESPONSE REGULATOR receiver
E3162_RS21175	COG5002	protein histidine kinase activity
E3162_RS21180	COG3501	Rhs element vgr protein
E3162_RS21190	COG4104	PAAR repeat-containing protein
E3162_RS21190	COG3209	COG3209 Rhs family protein
E3162_RS21200	COG4104	PAAR repeat-containing protein
E3162_RS21200	COG3209	COG3209 Rhs family protein
E3162_RS21210	COG5433	transposase activity
E3162_RS21215	COG1215	transferase activity, transferring glycosyl groups
E3162_RS21220	COG4783	chaperone-mediated protein folding
E3162_RS21230	COG2207	Transcriptional regulator
E3162_RS21240	COG2197	response regulator
E3162_RS21245	COG3539	Fimbrial protein
E3162_RS21250	COG3539	Fimbrial protein
E3162_RS21255	COG3188	usher protein
E3162_RS21260	COG3121	Chaperone
E3162_RS21265	COG3539	Fimbrial protein
E3162_RS21275	COG2501	S4 domain
E3162_RS21280	COG1988	membrane-bound metal-dependent
E3162_RS21290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E3162_RS21300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3162_RS21305	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E3162_RS21310	COG0549	Belongs to the carbamate kinase family
E3162_RS21320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3162_RS21325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3162_RS21330	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E3162_RS21335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3162_RS21340	COG3257	ureidoglycine aminohydrolase activity
E3162_RS21345	COG1929	Belongs to the glycerate kinase type-1 family
E3162_RS21350	COG2233	PERMEase
E3162_RS21360	COG1953	Uracil, thiamine, allantoin
E3162_RS21365	COG2084	Dehydrogenase
E3162_RS21370	COG3622	Belongs to the hyi family
E3162_RS21375	COG3960	tartronate-semialdehyde synthase activity
E3162_RS21380	COG1414	Transcriptional regulator
E3162_RS21390	COG0583	DNA-binding transcription factor activity
E3162_RS21410	COG3209	COG3209 Rhs family protein
E3162_RS21415	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E3162_RS21420	COG4181	ATPase activity
E3162_RS21425	COG2755	lipolytic protein G-D-S-L family
E3162_RS21430	COG0300	oxidoreductase activity
E3162_RS21435	COG3118	belongs to the thioredoxin family
E3162_RS21440	COG0390	transport system, permease component
E3162_RS21445	COG4619	ABC transporter
E3162_RS21450	COG0330	HflC and HflK could
E3162_RS21455	COG1585	Membrane protein implicated in regulation of membrane protease activity
E3162_RS21475	COG0789	Transcriptional regulator
E3162_RS21500	COG0531	amino acid
E3162_RS21505	COG2066	Belongs to the glutaminase family
E3162_RS21510	COG2217	Heavy metal translocating P-type atpase
E3162_RS21515	COG3093	addiction module antidote protein HigA
E3162_RS21520	COG3735	TraB family
E3162_RS21525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3162_RS21530	COG0737	Belongs to the 5'-nucleotidase family
E3162_RS21535	COG2223	nitrite transmembrane transporter activity
E3162_RS21540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E3162_RS21540	COG4651	solute:proton antiporter activity
E3162_RS21545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3162_RS21580	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3162_RS21590	COG2832	Protein of unknown function (DUF454)
E3162_RS21595	COG3923	Primosomal replication protein n
E3162_RS21605	COG3264	Mechanosensitive ion channel
E3162_RS21605	COG1196	nuclear chromosome segregation
E3162_RS21610	COG1309	transcriptional regulator
E3162_RS21615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3162_RS21620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3162_RS21635	COG0110	maltose O-acetyltransferase activity
E3162_RS21645	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E3162_RS21650	COG5507	3-demethylubiquinone-9 3-methyltransferase
E3162_RS21660	COG3695	enzyme binding
E3162_RS21665	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E3162_RS21670	COG1946	Acyl-CoA thioesterase
E3162_RS21675	COG0004	ammonium transporteR
E3162_RS21680	COG0347	Belongs to the P(II) protein family
E3162_RS21685	COG1132	(ABC) transporter
E3162_RS21690	COG1132	(ABC) transporter
E3162_RS21695	COG1522	sequence-specific DNA binding
E3162_RS21705	COG4533	DNA binding
E3162_RS21715	COG0824	Thioesterase
E3162_RS21720	COG1555	photosystem II stabilization
E3162_RS21725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3162_RS21730	COG0776	regulation of translation
E3162_RS21735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E3162_RS21755	COG0271	Belongs to the BolA IbaG family
E3162_RS21760	COG3056	Lipoprotein
E3162_RS21765	COG2223	nitrite transmembrane transporter activity
E3162_RS21770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E3162_RS21775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E3162_RS21780	COG1845	cytochrome c oxidase, subunit III
E3162_RS21785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E3162_RS21795	COG2814	Major facilitator Superfamily
E3162_RS21805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3162_RS21810	COG0693	protein deglycase activity
E3162_RS21825	COG0142	geranyltranstransferase activity
E3162_RS21835	COG0667	Aldo Keto reductase
E3162_RS21845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E3162_RS21850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E3162_RS21865	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3162_RS21865	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3162_RS21875	COG4238	major outer membrane lipoprotein
E3162_RS21880	COG3248	Nucleoside-binding outer membrane protein
E3162_RS21885	COG1403	HNH endonuclease
E3162_RS21895	COG3609	addiction module antidote protein, CC2985 family
E3162_RS21900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3162_RS21905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3162_RS21910	COG1862	Preprotein translocase
E3162_RS21935	COG0366	Alpha amylase catalytic
E3162_RS21940	COG1113	amino acid transport
E3162_RS21945	COG1114	Component of the transport system for branched-chain amino acids
E3162_RS21950	COG5002	protein histidine kinase activity
E3162_RS21955	COG0745	RESPONSE REGULATOR receiver
E3162_RS21960	COG0420	3'-5' exonuclease activity
E3162_RS21965	COG0419	ATPase involved in DNA repair
E3162_RS21970	COG2814	Major facilitator Superfamily
E3162_RS21975	COG1940	carbohydrate kinase activity
E3162_RS22000	COG4126	flavin adenine dinucleotide binding
E3162_RS22020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E3162_RS22025	COG3706	GGDEF domain
E3162_RS22035	COG1785	Belongs to the alkaline phosphatase family
E3162_RS22050	COG1181	Belongs to the D-alanine--D-alanine ligase family
E3162_RS22070	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E3162_RS22075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3162_RS22080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3162_RS22085	COG3468	outer membrane autotransporter barrel domain protein
E3162_RS22090	COG0113	porphobilinogen synthase activity
E3162_RS22095	COG2175	clavaminate synthase activity
E3162_RS22100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3162_RS22105	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E3162_RS22110	COG4521	taurine ABC transporter
E3162_RS22125	COG2271	Major facilitator Superfamily
E3162_RS22130	COG1840	ABC-type Fe3 transport system, periplasmic component
E3162_RS22140	COG3842	ATPase activity
E3162_RS22155	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
E3162_RS22160	COG3122	Protein conserved in bacteria
E3162_RS22170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E3162_RS22185	COG0596	Alpha beta hydrolase
E3162_RS22200	COG1414	Transcriptional regulator
E3162_RS22205	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3162_RS22215	COG1609	Transcriptional regulator
E3162_RS22220	COG3250	beta-galactosidase activity
E3162_RS22225	COG2223	nitrite transmembrane transporter activity
E3162_RS22230	COG0110	maltose O-acetyltransferase activity
E3162_RS22235	COG2807	transmembrane transport
E3162_RS22245	COG0288	reversible hydration of carbon dioxide
E3162_RS22250	COG0583	DNA-binding transcription factor activity
E3162_RS22255	COG0402	S-adenosylhomocysteine deaminase activity
E3162_RS22260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E3162_RS22265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3162_RS22270	COG2079	MmgE PrpD family protein
E3162_RS22275	COG0372	Belongs to the citrate synthase family
E3162_RS22280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
E3162_RS22285	COG3829	transcription factor binding
E3162_RS22295	COG1280	lysine exporter protein (LysE YggA)
E3162_RS22310	COG1064	alcohol dehydrogenase
E3162_RS22320	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3162_RS22325	COG1129	ABC transporter
E3162_RS22330	COG1879	ABC-type sugar transport system periplasmic component
E3162_RS22340	COG0402	S-adenosylhomocysteine deaminase activity
E3162_RS22345	COG0549	Belongs to the carbamate kinase family
E3162_RS22355	COG1304	FMN binding
E3162_RS22360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3162_RS22370	COG0666	response to abiotic stimulus
E3162_RS22385	COG2200	EAL domain
E3162_RS22385	COG2771	luxR family
E3162_RS22395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3162_RS22430	COG2200	EAL domain
E3162_RS22430	COG2771	luxR family
E3162_RS22455	COG1556	Lactate utilization protein
E3162_RS22460	COG1139	Iron-sulfur cluster binding protein
E3162_RS22465	COG0247	lactate metabolic process
E3162_RS22470	COG2207	Transcriptional regulator
E3162_RS22475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3162_RS22485	COG3059	membrane
E3162_RS22490	COG0656	L-ascorbic acid biosynthetic process
E3162_RS22495	COG2207	Transcriptional regulator
E3162_RS22495	COG3708	Transcriptional regulator
E3162_RS22500	COG1388	LysM domain
E3162_RS22515	COG0583	DNA-binding transcription factor activity
E3162_RS22520	COG1073	alpha beta
E3162_RS22525	COG1902	pentaerythritol trinitrate reductase activity
E3162_RS22535	COG4372	Transposase
E3162_RS22540	COG3436	PFAM IS66 Orf2 family protein
E3162_RS22580	COG3188	usher protein
E3162_RS22590	COG3121	Chaperone
E3162_RS22595	COG0727	PFAM Uncharacterised protein family (UPF0153)
E3162_RS22600	COG3477	response to acidic pH
E3162_RS22605	COG2080	2 iron, 2 sulfur cluster binding
E3162_RS22610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E3162_RS22615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E3162_RS22620	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
E3162_RS22635	COG0583	DNA-binding transcription factor activity
E3162_RS22695	COG0582	viral genome integration into host DNA
E3162_RS22715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3162_RS22735	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3162_RS22740	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E3162_RS22745	COG1690	Belongs to the RtcB family
E3162_RS22750	COG0454	-acetyltransferase
E3162_RS22760	COG2161	toxin-antitoxin pair type II binding
E3162_RS22765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3162_RS22785	COG0791	NLP P60 protein
E3162_RS22790	COG3077	Addiction module antitoxin, RelB DinJ family
E3162_RS22795	COG3041	Addiction module toxin RelE StbE family
E3162_RS22800	COG3034	peptidoglycan biosynthetic process
E3162_RS22805	COG0121	glutamine amidotransferase
E3162_RS22815	COG1960	acyl-CoA dehydrogenase activity
E3162_RS22825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3162_RS22830	COG5433	transposase activity
E3162_RS22845	COG3209	COG3209 Rhs family protein
E3162_RS22850	COG5433	transposase activity
E3162_RS22860	COG3209	COG3209 Rhs family protein
E3162_RS22870	COG3209	COG3209 Rhs family protein
E3162_RS22875	COG3501	Rhs element vgr protein
E3162_RS22990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3162_RS23000	COG2226	methyltransferase
E3162_RS23010	COG1388	LysM domain
E3162_RS23010	COG0741	lytic transglycosylase activity
E3162_RS23015	COG2226	methyltransferase
E3162_RS23025	COG0583	DNA-binding transcription factor activity
E3162_RS23030	COG0656	L-ascorbic acid biosynthetic process
E3162_RS23065	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3162_RS23070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E3162_RS23075	COG2011	ABC-type metal ion transport system permease component
E3162_RS23080	COG1464	Belongs to the NlpA lipoprotein family
E3162_RS23090	COG1720	tRNA m6t6A37 methyltransferase activity
E3162_RS23100	COG0791	NLP P60 protein
E3162_RS23105	COG3015	lipoprotein NlpE involved in copper resistance
E3162_RS23110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E3162_RS23115	COG4681	YaeQ
E3162_RS23125	COG4568	rho-dependent transcription termination
E3162_RS23130	COG0037	tRNA processing
E3162_RS23135	COG0346	lactoylglutathione lyase activity
E3162_RS23150	COG0587	DNA-directed DNA polymerase activity
E3162_RS23175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E3162_RS23180	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
E3162_RS23190	COG0750	zinc metalloprotease
E3162_RS23195	COG0575	Belongs to the CDS family
E3162_RS23200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E3162_RS23205	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
E3162_RS23230	COG0024	Methionine aminopeptidase
E3162_RS23250	COG3835	regulator
E3162_RS23255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3162_RS23270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3162_RS23275	COG2860	membrane
E3162_RS23300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3162_RS23305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3162_RS23310	COG1120	ATPase activity
E3162_RS23315	COG4774	siderophore transport
E3162_RS23320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3162_RS23325	COG1643	Atp-dependent helicase
E3162_RS23330	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E3162_RS23340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3162_RS23345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E3162_RS23350	COG0617	tRNA 3'-terminal CCA addition
E3162_RS23355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3162_RS23365	COG3121	Chaperone
E3162_RS23370	COG3188	usher protein
E3162_RS23375	COG3539	Fimbrial protein
E3162_RS23380	COG3539	Fimbrial protein
E3162_RS23405	COG5464	transposase or invertase
E3162_RS23415	COG0726	polysaccharide deacetylase
E3162_RS23420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS23425	COG0842	Transport permease protein
E3162_RS23430	COG1131	(ABC) transporter
E3162_RS23435	COG0288	reversible hydration of carbon dioxide
E3162_RS23440	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E3162_RS23445	COG4993	Dehydrogenase
E3162_RS23450	COG2132	Multicopper oxidase
E3162_RS23475	COG1049	propionate catabolic process, 2-methylcitrate cycle
E3162_RS23480	COG3064	Membrane
E3162_RS23485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3162_RS23490	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3162_RS23495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E3162_RS23500	COG2186	Transcriptional regulator
E3162_RS23505	COG1113	amino acid transport
E3162_RS23510	COG3725	Membrane protein required for beta-lactamase induction
E3162_RS23515	COG3023	N-Acetylmuramoyl-L-alanine amidase
E3162_RS23520	COG0157	Belongs to the NadC ModD family
E3162_RS23525	COG4969	Belongs to the N-Me-Phe pilin family
E3162_RS23530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3162_RS23535	COG1459	type II secretion system
E3162_RS23545	COG0237	dephospho-CoA kinase activity
E3162_RS23560	COG0494	nUDIX hydrolase
E3162_RS23580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3162_RS23585	COG0849	cell division
E3162_RS23590	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E3162_RS23595	COG1181	Belongs to the D-alanine--D-alanine ligase family
E3162_RS23610	COG0772	Belongs to the SEDS family
E3162_RS23615	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E3162_RS23625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3162_RS23630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E3162_RS23635	COG0768	penicillin binding
E3162_RS23640	COG3116	cell division
E3162_RS23655	COG1609	Transcriptional regulator
E3162_RS23665	COG0440	acetolactate synthase activity
E3162_RS23670	COG0028	Belongs to the TPP enzyme family
E3162_RS23675	COG0583	DNA-binding transcription factor activity
E3162_RS23690	COG0473	3-isopropylmalate dehydrogenase activity
E3162_RS23710	COG4533	DNA binding
E3162_RS23720	COG4143	(ABC) transporter
E3162_RS23725	COG1178	ABC-type Fe3 transport system permease component
E3162_RS23730	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
E3162_RS23735	COG0586	Pfam SNARE associated Golgi protein
E3162_RS23740	COG4977	sequence-specific DNA binding
E3162_RS23755	COG0235	Class ii aldolase
E3162_RS23760	COG0417	DNA replication proofreading
E3162_RS23770	COG0564	pseudouridine synthase activity
E3162_RS23780	COG1357	PFAM Pentapeptide repeats (8 copies)
E3162_RS23785	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E3162_RS23790	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E3162_RS23795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3162_RS23830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
E3162_RS23845	COG2271	Major facilitator Superfamily
E3162_RS23850	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3162_RS23855	COG0644	oxidoreductase
E3162_RS23905	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E3162_RS23910	COG0505	Belongs to the CarA family
E3162_RS23930	COG1047	Peptidyl-prolyl cis-trans
E3162_RS23945	COG0196	riboflavin kinase activity
E3162_RS23970	COG3121	Chaperone
E3162_RS23975	COG3188	usher protein
E3162_RS23985	COG0583	DNA-binding transcription factor activity
E3162_RS24015	COG4735	regulation of single-species biofilm formation
E3162_RS24020	COG1584	GPR1 FUN34 yaaH family protein
E3162_RS24025	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3162_RS24030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3162_RS24035	COG1115	amino acid carrier protein
E3162_RS24050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3162_RS24060	COG0460	homoserine dehydrogenase
E3162_RS24060	COG0527	aspartate kinase activity
E3162_RS24070	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E3162_RS24080	COG0745	RESPONSE REGULATOR receiver
E3162_RS24085	COG4452	Inner membrane protein CreD
E3162_RS24090	COG2205	protein histidine kinase activity
E3162_RS24095	COG0745	RESPONSE REGULATOR receiver
E3162_RS24100	COG3045	CreA protein
E3162_RS24105	COG2207	Transcriptional regulator
E3162_RS24105	COG3708	Transcriptional regulator
E3162_RS24115	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
E3162_RS24125	COG0741	lytic transglycosylase activity
E3162_RS24130	COG0488	(ABC) transporter
E3162_RS24140	COG1056	cytidyltransferase-related domain
E3162_RS24140	COG3172	ATPase kinase involved in NAD metabolism
E3162_RS24145	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3162_RS24150	COG0560	Phosphoserine phosphatase
E3162_RS24160	COG3726	membrane protein affecting hemolysin expression
E3162_RS24160	COG0095	Lipoate-protein ligase
E3162_RS24195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3162_RS24200	COG0084	hydrolase, TatD family'
E3162_RS24205	COG4667	esterase of the alpha-beta hydrolase superfamily
E3162_RS24215	COG2823	Periplasmic or secreted lipoprotein
E3162_RS24225	COG1011	Hydrolase
E3162_RS24230	COG0456	acetyltransferase
E3162_RS24235	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E3162_RS24255	COG4114	ferric iron reductase
E3162_RS24260	COG2197	response regulator
E3162_RS24265	COG2197	response regulator
E3162_RS24270	COG2966	Psort location CytoplasmicMembrane, score
E3162_RS24285	COG1484	DNA-dependent DNA replication
E3162_RS24300	COG1063	alcohol dehydrogenase
E3162_RS24305	COG1802	Transcriptional regulator
E3162_RS24310	COG2271	Major facilitator Superfamily
E3162_RS24315	COG0840	transmembrane signaling receptor activity
E3162_RS24325	COG1966	Carbon starvation protein
E3162_RS24330	COG2879	small protein
E3162_RS24335	COG0523	cobalamin synthesis protein
E3162_RS24360	COG0732	type I restriction modification DNA specificity domain
E3162_RS24380	COG5457	Domain of unknown function (DUF1127)
E3162_RS24385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3162_RS24395	COG2814	Major facilitator Superfamily
E3162_RS24400	COG2733	membrane
E3162_RS24405	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
E3162_RS24410	COG1924	4 iron, 4 sulfur cluster binding
E3162_RS24425	COG3204	pilus organization
E3162_RS24430	COG0477	Major facilitator Superfamily
E3162_RS24445	COG3366	ferrous iron transmembrane transporter activity
E3162_RS24450	COG0700	Nucleoside recognition
E3162_RS24455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3162_RS24480	COG2186	Transcriptional regulator
E3162_RS24485	COG0246	Mannitol dehydrogenase
E3162_RS24495	COG2610	gluconate transmembrane transporter activity
E3162_RS24500	COG3539	Fimbrial protein
E3162_RS24505	COG3539	Fimbrial protein
E3162_RS24510	COG3539	Fimbrial protein
E3162_RS24515	COG3188	usher protein
E3162_RS24520	COG3121	Chaperone
E3162_RS24525	COG3539	Fimbrial protein
E3162_RS24530	COG3539	Fimbrial protein
E3162_RS24535	COG4974	Belongs to the 'phage' integrase family
E3162_RS24540	COG0582	viral genome integration into host DNA
E3162_RS24545	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E3162_RS24550	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
E3162_RS24565	COG0210	DNA helicase
E3162_RS24570	COG1111	helicase
E3162_RS24570	COG1205	dead DEAH box helicase
E3162_RS24580	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
E3162_RS24625	COG0582	viral genome integration into host DNA
E3162_RS24680	COG1064	alcohol dehydrogenase
E3162_RS24685	COG0433	COG0433 Predicted ATPase
E3162_RS24690	COG0795	lipopolysaccharide-transporting ATPase activity
E3162_RS24695	COG0795	lipopolysaccharide-transporting ATPase activity
E3162_RS24705	COG2927	DNA polymerase III (CHI subunit)
E3162_RS24715	COG4269	membrane
E3162_RS24720	COG0456	acetyltransferase
E3162_RS24725	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
E3162_RS24730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E3162_RS24740	COG2731	YhcH YjgK YiaL family protein
E3162_RS24745	COG1309	transcriptional regulator
E3162_RS24750	COG1028	Short-chain dehydrogenase reductase Sdr
E3162_RS24755	COG0251	oxidation-reduction process
E3162_RS24775	COG0251	oxidation-reduction process
E3162_RS24780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E3162_RS24790	COG1609	Transcriptional regulator
E3162_RS24795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3162_RS24795	COG1263	PTS System
E3162_RS24800	COG0366	Alpha amylase catalytic
E3162_RS24805	COG1328	CTP reductase activity
E3162_RS24810	COG0602	queuosine metabolic process
E3162_RS24815	COG3783	Cytochrome b(562)
E3162_RS24820	COG0312	modulator of DNA gyrase
E3162_RS24830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E3162_RS24840	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3162_RS24845	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3162_RS24850	COG1129	ABC transporter
E3162_RS24855	COG1879	ABC-type sugar transport system periplasmic component
E3162_RS24860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E3162_RS24865	COG2337	Toxic component of a toxin-antitoxin (TA) module
E3162_RS24870	COG2336	PFAM SpoVT AbrB
E3162_RS24875	COG2105	PFAM AIG2 family protein
E3162_RS24880	COG2911	Protein conserved in bacteria
E3162_RS24885	COG0729	surface antigen
E3162_RS24895	COG1253	flavin adenine dinucleotide binding
E3162_RS24905	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E3162_RS24915	COG1218	3'(2'),5'-bisphosphate nucleotidase
E3162_RS24920	COG0737	Belongs to the 5'-nucleotidase family
E3162_RS24925	COG1733	regulation of RNA biosynthetic process
E3162_RS24930	COG0702	epimerase
E3162_RS24935	COG0697	spore germination
E3162_RS24945	COG1113	amino acid transport
E3162_RS24950	COG0545	Peptidyl-prolyl cis-trans isomerase
E3162_RS24955	COG3061	Opacity-associated protein A
E3162_RS24965	COG0675	Transposase, IS605 OrfB family
E3162_RS24990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E3162_RS25025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS25030	COG3414	Phosphotransferase system galactitol-specific IIB component
E3162_RS25035	COG3037	sugar-specific permease SgaT UlaA
E3162_RS25050	COG1073	alpha beta
E3162_RS25055	COG3650	response to hydrogen peroxide
E3162_RS25065	COG1960	acyl-CoA dehydrogenase activity
E3162_RS25070	COG0754	glutathionylspermidine amidase activity
E3162_RS25075	COG5463	Belongs to the UPF0441 family
E3162_RS25080	COG3766	membrane
E3162_RS25090	COG1842	Phage shock protein A
E3162_RS25095	COG3789	protein conserved in bacteria
E3162_RS25100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3162_RS25105	COG0557	exoribonuclease II activity
E3162_RS25120	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E3162_RS25125	COG0330	HflC and HflK could
E3162_RS25130	COG0330	HflC and HflK could
E3162_RS25135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E3162_RS25155	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3162_RS25160	COG0802	atpase or kinase
E3162_RS25165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3162_RS25165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E3162_RS25195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
E3162_RS25210	COG3264	Mechanosensitive ion channel
E3162_RS25210	COG1511	domain protein
E3162_RS25215	COG0531	amino acid
E3162_RS25225	COG1053	succinate dehydrogenase
E3162_RS25230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3162_RS25245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3162_RS25250	COG3040	lipid binding
E3162_RS25255	COG2076	Multidrug Resistance protein
E3162_RS25260	COG5510	response to toxic substance
E3162_RS25265	COG5510	response to toxic substance
E3162_RS25275	COG1509	lysine 2,3-aminomutase activity
E3162_RS25300	COG0531	amino acid
E3162_RS25305	COG3030	protein affecting phage T7 exclusion by the F plasmid
E3162_RS25310	COG1027	Aspartate ammonia-lyase
E3162_RS25315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3162_RS25325	COG4232	protein-disulfide reductase activity
E3162_RS25330	COG1309	transcriptional regulator
E3162_RS25340	COG3710	Transcriptional regulator
E3162_RS25345	COG0531	amino acid
E3162_RS25350	COG1982	Orn Lys Arg decarboxylase major
E3162_RS25355	COG3104	oligopeptide transport
E3162_RS25360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E3162_RS25375	COG2388	GCN5-related N-acetyl-transferase
E3162_RS25380	COG3592	Divergent 4Fe-4S mono-cluster
E3162_RS25385	COG3290	protein histidine kinase activity
E3162_RS25390	COG4565	transcriptional regulatory protein
E3162_RS25395	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3162_RS25400	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3162_RS25400	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3162_RS25405	COG3647	Membrane
E3162_RS25410	COG2211	Major facilitator Superfamily
E3162_RS25415	COG1486	melibiose metabolic process
E3162_RS25420	COG2169	Transcriptional regulator
E3162_RS25425	COG1982	Orn Lys Arg decarboxylase major
E3162_RS25430	COG2207	Transcriptional regulator
E3162_RS25435	COG0531	amino acid
E3162_RS25440	COG2194	sulfuric ester hydrolase activity
E3162_RS25445	COG0745	RESPONSE REGULATOR receiver
E3162_RS25450	COG0642	Histidine kinase
E3162_RS25460	COG0477	Major facilitator Superfamily
E3162_RS25470	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3162_RS25475	COG2824	Alkylphosphonate utilization operon protein PhnA
E3162_RS25480	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E3162_RS25485	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
E3162_RS25490	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
E3162_RS25495	COG3639	organic phosphonate transmembrane transporter activity
E3162_RS25500	COG2188	Transcriptional regulator
E3162_RS25505	COG3624	Phosphonate C-P lyase system protein PhnG
E3162_RS25510	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
E3162_RS25515	COG3626	phosphonate metabolism
E3162_RS25520	COG3627	carbon phosphorus lyase activity
E3162_RS25525	COG4107	phosphonate C-P lyase system protein PhnK
E3162_RS25530	COG4778	phosphonate C-P lyase system protein PhnL
E3162_RS25535	COG3454	Phosphonate metabolism
E3162_RS25540	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
E3162_RS25545	COG0456	acetyltransferase
E3162_RS25550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3162_RS25565	COG1129	ABC transporter
E3162_RS25570	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3162_RS25590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3162_RS25600	COG2015	COG2015, Alkyl sulfatase and related hydrolases
E3162_RS25610	COG1566	PFAM secretion protein HlyD family protein
E3162_RS25615	COG1289	transmembrane transporter activity
E3162_RS25620	COG1538	Outer membrane efflux protein
E3162_RS25630	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E3162_RS25635	COG1301	dicarboxylic acid transport
E3162_RS25640	COG4235	cytochrome complex assembly
E3162_RS25645	COG3088	subunit of a heme lyase
E3162_RS25650	COG1138	Cytochrome C-type biogenesis protein
E3162_RS25655	COG3301	Polysulphide reductase, NrfD
E3162_RS25660	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS25665	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E3162_RS25675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3162_RS25680	COG3162	membrane
E3162_RS25690	COG1357	PFAM Pentapeptide repeats (8 copies)
E3162_RS25695	COG0025	NhaP-type Na H and K H
E3162_RS25700	COG2252	PERMEase
E3162_RS25705	COG0789	Transcriptional regulator
E3162_RS25710	COG2207	Transcriptional regulator
E3162_RS25715	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E3162_RS25725	COG0629	single-stranded DNA binding
E3162_RS25730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E3162_RS25735	COG2315	Protein conserved in bacteria
E3162_RS25740	COG0432	Pfam Uncharacterised protein family UPF0047
E3162_RS25745	COG3700	Belongs to the class B bacterial acid phosphatase family
E3162_RS25755	COG1448	Aminotransferase
E3162_RS25760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E3162_RS25765	COG0305	Participates in initiation and elongation during chromosome replication
E3162_RS25780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3162_RS25820	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3162_RS25840	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E3162_RS25880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3162_RS25890	COG0735	belongs to the Fur family
E3162_RS25895	COG3237	CsbD-like
E3162_RS25900	COG0534	Mate efflux family protein
E3162_RS25910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E3162_RS25930	COG1357	PFAM Pentapeptide repeats (8 copies)
E3162_RS25945	COG3842	ATPase activity
E3162_RS25950	COG2182	Extracellular solute-binding protein
E3162_RS25955	COG1175	transmembrane transport
E3162_RS25960	COG3833	ABC-type maltose transport systems, permease component
E3162_RS25970	COG2814	Major facilitator Superfamily
E3162_RS25970	COG0477	Major facilitator Superfamily
E3162_RS25990	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3162_RS26015	COG0527	aspartate kinase activity
E3162_RS26025	COG1187	pseudouridine synthase activity
E3162_RS26070	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3162_RS26075	COG0646	methionine synthase
E3162_RS26075	COG1410	methionine synthase
E3162_RS26080	COG1414	Transcriptional regulator
E3162_RS26095	COG2224	Isocitrate lyase
E3162_RS26100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E3162_RS26110	COG0456	acetyltransferase
E3162_RS26140	COG0151	Belongs to the GarS family
E3162_RS26145	COG2204	response regulator
E3162_RS26150	COG4191	Histidine kinase
E3162_RS26155	COG3678	ATP-independent chaperone mediated protein folding
E3162_RS26170	COG3068	Protein conserved in bacteria
E3162_RS26205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3162_RS26210	COG2104	thiamine diphosphate biosynthetic process
E3162_RS26215	COG2022	thiamine diphosphate biosynthetic process
E3162_RS26220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
E3162_RS26260	COG0250	Participates in transcription elongation, termination and antitermination
E3162_RS26265	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3162_RS26300	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
E3162_RS26300	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
E3162_RS26305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E3162_RS26330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
E3162_RS26335	COG4206	TonB-dependent receptor
E3162_RS26340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E3162_RS26350	COG1309	transcriptional regulator
E3162_RS26355	COG0477	Major facilitator Superfamily
E3162_RS26360	COG1473	amidohydrolase
E3162_RS26370	COG0583	DNA-binding transcription factor activity
E3162_RS26385	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E3162_RS26400	COG2194	sulfuric ester hydrolase activity
E3162_RS26405	COG2207	Transcriptional regulator
E3162_RS26410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3162_RS26415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3162_RS26420	COG1882	Formate acetyltransferase
E3162_RS26425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3162_RS26430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3162_RS26435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS26435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS26435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3162_RS26440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3162_RS26445	COG0371	Dehydrogenase
E3162_RS26450	COG3738	Protein conserved in bacteria
E3162_RS26455	COG0697	spore germination
E3162_RS26465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3162_RS26470	COG0527	aspartate kinase activity
E3162_RS26470	COG0460	homoserine dehydrogenase
E3162_RS26475	COG0626	cystathionine gamma-synthase activity
E3162_RS26485	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
E3162_RS26500	COG3209	COG3209 Rhs family protein
E3162_RS26510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3162_RS26515	COG1609	Transcriptional regulator
E3162_RS26520	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3162_RS26535	COG1575	Belongs to the MenA family. Type 1 subfamily
E3162_RS26560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3162_RS26570	COG1494	fructose-1,6-bisphosphatase
E3162_RS26580	COG0589	response to stress
E3162_RS26585	COG3691	Protein conserved in bacteria
E3162_RS26590	COG3152	Membrane
E3162_RS26610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
E3162_RS26625	COG3678	ATP-independent chaperone mediated protein folding
E3162_RS26630	COG0745	RESPONSE REGULATOR receiver
E3162_RS26635	COG2205	protein histidine kinase activity
E3162_RS26640	COG2258	MOSC domain
E3162_RS26650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E3162_RS26660	COG4977	sequence-specific DNA binding
E3162_RS26660	COG1917	Cupin 2, conserved barrel domain protein
E3162_RS26695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS26700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3162_RS26700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3162_RS26705	COG1363	Peptidase, m42
E3162_RS26710	COG3711	transcriptional antiterminator
E3162_RS26710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3162_RS26730	COG0437	4 iron, 4 sulfur cluster binding
E3162_RS26735	COG2864	formate dehydrogenase
E3162_RS26745	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E3162_RS26750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E3162_RS26765	COG0456	acetyltransferase
E3162_RS26780	COG1011	Hydrolase
E3162_RS26785	COG1349	DNA-binding transcription factor activity
E3162_RS26790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3162_RS26795	COG2084	Dehydrogenase
E3162_RS26800	COG3684	Belongs to the aldolase LacD family
E3162_RS26805	COG2942	2-epimerase
E3162_RS26810	COG2017	converts alpha-aldose to the beta-anomer
E3162_RS26820	COG1501	Belongs to the glycosyl hydrolase 31 family
E3162_RS26825	COG2211	Major facilitator Superfamily
E3162_RS26830	COG2211	Major facilitator Superfamily
E3162_RS26835	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E3162_RS26840	COG2271	Major facilitator Superfamily
E3162_RS26845	COG1082	Xylose isomerase domain protein TIM barrel
E3162_RS26850	COG2188	Transcriptional regulator
E3162_RS26860	COG0174	glutamine synthetase
E3162_RS26865	COG3852	Histidine kinase
E3162_RS26870	COG2204	response regulator
E3162_RS26880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3162_RS26885	COG3078	GTPase activator activity
E3162_RS26895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3162_RS26895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3162_RS26900	COG0204	Acyl-transferase
E3162_RS26905	COG5339	Protein conserved in bacteria
E3162_RS26910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3162_RS26915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
E3162_RS26920	COG3084	Protein conserved in bacteria
E3162_RS26925	COG0746	molybdenum cofactor guanylyltransferase activity
E3162_RS26930	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3162_RS26960	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
E3162_RS26965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3162_RS26970	COG1739	Uncharacterized protein family UPF0029
E3162_RS26985	COG0183	Belongs to the thiolase family
E3162_RS26990	COG0543	2 iron, 2 sulfur cluster binding
E3162_RS26995	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E3162_RS27000	COG0250	Participates in transcription elongation, termination and antitermination
E3162_RS27005	COG0084	hydrolase, TatD family'
E3162_RS27010	COG0805	protein transport
E3162_RS27015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3162_RS27020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3162_RS27030	COG3165	ubiquinone biosynthetic process from chorismate
E3162_RS27040	COG1322	Protein conserved in bacteria
E3162_RS27045	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
E3162_RS27050	COG0412	Dienelactone hydrolase
E3162_RS27060	COG0583	DNA-binding transcription factor activity
E3162_RS27065	COG0697	spore germination
E3162_RS27070	COG0561	phosphatase activity
E3162_RS27075	COG2267	carboxylic ester hydrolase activity
E3162_RS27080	COG1280	lysine exporter protein (LysE YggA)
E3162_RS27085	COG1280	lysine exporter protein (LysE YggA)
E3162_RS27090	COG0514	ATP-dependent DNA helicase (RecQ)
E3162_RS27095	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
E3162_RS27100	COG2050	protein possibly involved in aromatic compounds catabolism
E3162_RS27105	COG2962	Rard protein
E3162_RS27130	COG0598	Magnesium transport protein CorA
E3162_RS27135	COG3698	Phosphodiester glycosidase
E3162_RS27140	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
E3162_RS27145	COG0210	DNA helicase
E3162_RS27150	COG1011	Hydrolase
E3162_RS27160	COG3159	Protein conserved in bacteria
E3162_RS27170	COG5567	small periplasmic lipoprotein
E3162_RS27180	COG3072	Adenylate cyclase
E3162_RS27190	COG1587	Uroporphyrinogen-III synthase
E3162_RS27195	COG2959	enzyme of heme biosynthesis
E3162_RS27200	COG3071	HemY protein
E3162_RS27205	COG3119	arylsulfatase activity
E3162_RS27210	COG0641	radical SAM
E3162_RS27240	COG1113	amino acid transport
E3162_RS27260	COG2244	polysaccharide biosynthetic process
E3162_RS27265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3162_RS27270	COG0456	acetyltransferase
E3162_RS27275	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E3162_RS27280	COG1088	dTDP-glucose 4,6-dehydratase activity
E3162_RS27285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3162_RS27290	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3162_RS27295	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E3162_RS27300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3162_RS27305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3162_RS27315	COG3118	belongs to the thioredoxin family
E3162_RS27330	COG0210	DNA helicase
E3162_RS27335	COG3692	DNA binding
E3162_RS27340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3162_RS27350	COG0583	DNA-binding transcription factor activity
E3162_RS27355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E3162_RS27365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E3162_RS27370	COG3978	acetolactate synthase activity
E3162_RS27390	COG0606	chelatase, subunit chli
E3162_RS27395	COG3085	chromosome segregation
E3162_RS27435	COG2186	Transcriptional regulator
E3162_RS27440	COG0477	Major facilitator Superfamily
E3162_RS27445	COG1609	Transcriptional regulator
E3162_RS27450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3162_RS27455	COG1879	ABC-type sugar transport system periplasmic component
E3162_RS27460	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3162_RS27465	COG1129	ABC transporter
E3162_RS27475	COG3158	transport of potassium into the cell
E3162_RS27495	COG1522	sequence-specific DNA binding
E3162_RS27500	COG0716	FMN binding
E3162_RS27605	COG2274	protein secretion by the type I secretion system
E3162_RS27775	COG1475	DNA binding
E3162_RS27860	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
E3162_RS27870	COG1525	nuclease
E3162_RS27950	COG3468	outer membrane autotransporter barrel domain protein
E3162_RS27960	COG0726	polysaccharide deacetylase
E3162_RS27965	COG0297	glycogen (starch) synthase activity
E3162_RS27970	COG2194	sulfuric ester hydrolase activity
E3162_RS27975	COG1560	Kdo2-lipid A biosynthetic process
E3162_RS27995	COG3436	PFAM IS66 Orf2 family protein
E3162_RS28000	COG4372	Transposase