locus-tag class description FDZ86_RS00015 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation FDZ86_RS00065 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FDZ86_RS00070 ENOG4108ZI2 Fimbrial protein FDZ86_RS00075 ENOG4108VCD Chaperone FDZ86_RS00085 ENOG4105CW0 outer membrane usher protein FDZ86_RS00090 ENOG4105I74 Fimbrial protein FDZ86_RS00095 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) FDZ86_RS00100 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) FDZ86_RS00105 ENOG4105C8U phosphate abc transporter FDZ86_RS00110 ENOG4105E2Z phosphate ABC transporter (Permease FDZ86_RS00115 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS00120 ENOG4108UTW Plays a role in the regulation of phosphate uptake FDZ86_RS00145 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 FDZ86_RS00150 ENOG4105C7N Xanthine uracil vitamin C permease FDZ86_RS00155 ENOG4108YYH Nadph-dependent fmn reductase FDZ86_RS00160 ENOG4105E8Q phosphopantetheinyl transferase FDZ86_RS00175 ENOG4108P6C Tryptophan transporter of low affinity FDZ86_RS00215 ENOG4105VG0 50S ribosomal protein l34 FDZ86_RS00230 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FDZ86_RS00240 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDZ86_RS00245 ENOG4105VP5 Bacterial protein of unknown function (DUF937) FDZ86_RS00250 ENOG410667J hydrolase FDZ86_RS00255 ENOG410657R replicase EC 2.7 FDZ86_RS00260 ENOG4107WAP fad NAD(P)-binding domain FDZ86_RS00265 ENOG4105D99 atp gtp-binding protein FDZ86_RS00270 ENOG4105R2A (LipO)protein FDZ86_RS00290 ENOG4105FDP GntR family transcriptional regulator FDZ86_RS00295 ENOG4105CI1 PTS System FDZ86_RS00300 ENOG4105F8D glycoside hydrolase family 4 FDZ86_RS00305 ENOG4108AHD Transcriptional regulator FDZ86_RS00310 ENOG4107RUZ Sss sodium solute transporter superfamily FDZ86_RS00315 ENOG4105CBG Sulfatase FDZ86_RS00320 ENOG4106DRA Inner membrane protein YidI FDZ86_RS00325 ENOG4105VG5 Membrane FDZ86_RS00330 ENOG4105JP4 Inner membrane protein yidG FDZ86_RS00335 ENOG4105J13 transcriptional regulator FDZ86_RS00340 ENOG4105E5M Multidrug resistance protein D FDZ86_RS00355 ENOG4105C7K acetolactate synthase FDZ86_RS00360 ENOG4105M71 acetolactate synthase 1 regulatory subunit FDZ86_RS00380 ENOG4108KX4 response regulator FDZ86_RS00385 ENOG4105BZU Histidine kinase FDZ86_RS00390 ENOG4105CXY transporter FDZ86_RS00395 ENOG4105CXY transporter FDZ86_RS00410 ENOG4108SAJ Protein of unknown function (DUF1198) FDZ86_RS00425 ENOG4107RTG Major Facilitator superfamily FDZ86_RS00430 ENOG4105T8A Uncharacterized protein YicS FDZ86_RS00435 ENOG4105D01 (LipO)protein FDZ86_RS00440 ENOG4108UZ3 Transporter FDZ86_RS00445 ENOG4105S8Q sugar efflux transporter FDZ86_RS00490 ENOG4108HHI Type III secretion system protein FDZ86_RS00495 ENOG41083GP type iii secretion FDZ86_RS00500 ENOG4108TN6 type iii secretion FDZ86_RS00505 ENOG4108IUF type iii secretion FDZ86_RS00565 ENOG4108JIR Flagellum-specific ATP synthase FDZ86_RS00605 ENOG41090V3 Tir chaperone protein (CesT) family FDZ86_RS00610 ENOG4105TNG K13735 adhesin invasin FDZ86_RS00620 ENOG4105UQF type iii secretion FDZ86_RS00665 ENOG4105E5H Transposase FDZ86_RS00670 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS00710 ENOG4105DFP Integrase FDZ86_RS00720 ENOG4105CT4 transporter FDZ86_RS00725 ENOG4105CJQ hydrolase, family 31 FDZ86_RS00730 ENOG4105JV1 AsmA family FDZ86_RS00735 ENOG4105C2W permease FDZ86_RS00740 ENOG4105D6U Sodium Glutamate Symporter FDZ86_RS00750 ENOG4105CB5 ATP-dependent DNA helicase recG FDZ86_RS00755 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase FDZ86_RS00760 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FDZ86_RS00770 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FDZ86_RS00780 ENOG4105EN6 Membrane FDZ86_RS00785 ENOG4105F5P DNA-damage-inducible protein d FDZ86_RS00790 ENOG4105DSJ YicC domain protein FDZ86_RS00810 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FDZ86_RS00815 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FDZ86_RS00825 ENOG4105KDC 50s ribosomal protein l28 FDZ86_RS00845 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FDZ86_RS00850 ENOG4105DKP glycosyl transferase, family 9 FDZ86_RS00855 ENOG4107RJ7 Glycosyl transferase (Group 1 FDZ86_RS00860 ENOG4107543 (lipo)polysaccharide FDZ86_RS00865 ENOG4106AH0 Glycosyl Transferase FDZ86_RS00870 ENOG4108PDR lipopolysaccharide core biosynthesis protein FDZ86_RS00875 ENOG4105X1N Glycosyl transferase family 8 FDZ86_RS00880 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase FDZ86_RS00885 ENOG4108FRV O-antigen ligase FDZ86_RS00890 ENOG4105D16 lipopolysaccharide heptosyltransferase i FDZ86_RS00895 ENOG4105XA0 heptosyltransferase ii FDZ86_RS00905 ENOG4108SEH involved in lipopolysaccharide biosynthesis FDZ86_RS00910 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FDZ86_RS00920 ENOG4105K64 Glycosyl transferase, family 2 FDZ86_RS00925 ENOG4105PXI polysaccharide deacetylase FDZ86_RS00930 ENOG41063SB peptidase FDZ86_RS00940 ENOG4107YZP Rhodanese domain protein FDZ86_RS00945 ENOG4105VW4 glutaredoxin 3 FDZ86_RS00960 ENOG4105D7W serine acetyltransferase FDZ86_RS00965 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FDZ86_RS00975 ENOG41073TP transcriptional regulator FDZ86_RS00980 ENOG4105DAA L-lactate FDZ86_RS00985 ENOG4105EUR Domain-Containing protein FDZ86_RS00990 ENOG4108WY4 inner membrane lipoprotein FDZ86_RS00995 ENOG4108YYI Protein of unknown function (DUF2810) FDZ86_RS01005 ENOG4105E61 Mannitol repressor protein FDZ86_RS01015 ENOG4105CTS PTS system mannitol-specific FDZ86_RS01020 ENOG4105FP6 Protein of unknown function (DUF3302) FDZ86_RS01025 ENOG4105EFX secretion protein, HlyD family FDZ86_RS01040 ENOG4105CNA YD repeat protein FDZ86_RS01045 ENOG4108U78 Glutathione S-transferase FDZ86_RS01055 ENOG4105EM7 Selenocysteine-specific translation elongation factor FDZ86_RS01060 ENOG4105C0A alcohol dehydrogenase FDZ86_RS01070 ENOG4105C26 Dehydrogenase FDZ86_RS01075 ENOG4105KK7 inner membrane protein YiaW FDZ86_RS01080 ENOG4105EFX secretion protein, HlyD family FDZ86_RS01085 ENOG4108Q2M Transcriptional regulator FDZ86_RS01090 ENOG4105GNX MltA-interacting MipA family protein FDZ86_RS01100 ENOG4105CT4 transporter FDZ86_RS01110 ENOG4105J4Q Transcriptional regulator FDZ86_RS01115 ENOG4108XIB electron transport protein ysaA FDZ86_RS01120 ENOG4105JKW Valine--pyruvate aminotransferase FDZ86_RS01125 ENOG4107T9C Alpha amylase catalytic region FDZ86_RS01130 ENOG4108UR8 BAX protein FDZ86_RS01135 ENOG4105T16 Transcriptional regulator (AraC family) FDZ86_RS01140 ENOG4108HWW ABC transporter FDZ86_RS01150 ENOG4105DFW ABC transporter FDZ86_RS01160 ENOG4105CMG Carbohydrate kinase FDZ86_RS01165 ENOG410688U Inner membrane protein yiaB FDZ86_RS01170 ENOG4108Z12 YiaAB two helix domain-containing protein FDZ86_RS01175 ENOG4105MEV Acyl-transferase FDZ86_RS01195 ENOG41060TC Hok gef cell toxic protein FDZ86_RS01205 ENOG4105MVF Transcriptional regulator FDZ86_RS01210 ENOG4106JH6 (LipO)protein FDZ86_RS01220 ENOG4108ZG0 Ompa motb domain protein FDZ86_RS01225 ENOG4107QY8 reductase FDZ86_RS01230 ENOG4105HNP -acetyltransferase FDZ86_RS01235 ENOG4108R3E Dna-3-methyladenine glycosylase i FDZ86_RS01240 ENOG4105EAX Putative lipase FDZ86_RS01245 ENOG4105FCD Major Facilitator FDZ86_RS01250 ENOG4106EAR Fimbrial protein FDZ86_RS01255 ENOG4108VCD Chaperone FDZ86_RS01265 ENOG4105MHR Fimbrial protein FDZ86_RS01275 ENOG4105DIJ Phosphoethanolamine transferase FDZ86_RS01285 ENOG4105DEF Extracellular solute-binding protein, family 5 FDZ86_RS01290 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FDZ86_RS01295 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FDZ86_RS01300 ENOG4105C3U ABC transporter FDZ86_RS01305 ENOG4108JQ7 (ABC) transporter FDZ86_RS01310 ENOG4105C44 Serine transporter FDZ86_RS01320 ENOG4105D1V cellulose synthase operon protein YhjU FDZ86_RS01325 ENOG4105WQA Cellulose biosynthesis protein BcsF FDZ86_RS01330 ENOG4105U74 cellulose biosynthesis protein BcsE FDZ86_RS01335 ENOG410661M cytoplasmic protein FDZ86_RS01350 ENOG4107QZ7 Cellulose synthase catalytic subunit FDZ86_RS01355 ENOG4107EEX Cellulose synthase regulator protein FDZ86_RS01360 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) FDZ86_RS01365 ENOG4105EJG cellulose synthase FDZ86_RS01370 ENOG4105BZU Histidine kinase FDZ86_RS01380 ENOG4105CS0 peptidase FDZ86_RS01390 ENOG4105CMB EAL domain-containing protein FDZ86_RS01395 ENOG41066T0 asmA family FDZ86_RS01400 ENOG4105CSH Transporter FDZ86_RS01405 ENOG4107H3J ribonuclease FDZ86_RS01410 ENOG4105CBN LysR family transcriptional regulator FDZ86_RS01415 ENOG4106S2D Transcriptional regulator FDZ86_RS01425 ENOG4105CA0 peroxidase FDZ86_RS01430 ENOG4105CVK Glutamate decarboxylase FDZ86_RS01435 ENOG4108NKV transcriptional regulator FDZ86_RS01445 ENOG4105BZS acriflavin resistance protein FDZ86_RS01450 ENOG4105C1P efflux transporter, rnd family, mfp subunit FDZ86_RS01460 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci FDZ86_RS01465 ENOG4108YK4 Acid-resistance membrane protein FDZ86_RS01470 ENOG41060V2 Acid-resistance protein FDZ86_RS01475 ENOG4105XXV Acid-resistance protein FDZ86_RS01480 ENOG4105KT7 mgtC SapB transporter FDZ86_RS01485 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS01490 ENOG4105EHG Permease protein FDZ86_RS01500 ENOG41090JE Utilization Protein FDZ86_RS01505 ENOG4105D4P Coproporphyrinogen iii oxidase FDZ86_RS01510 ENOG4107R4I Periplasmic binding protein FDZ86_RS01520 ENOG4107ENK receptor FDZ86_RS01525 ENOG4106QJH hemin transport protein FDZ86_RS01535 ENOG4105Y4Z Outer Membrane Lipoprotein FDZ86_RS01545 ENOG4105K89 arsenate reductase FDZ86_RS01550 ENOG4107R5R arsenical pump membrane protein FDZ86_RS01555 ENOG4105KBH arsR family transcriptional regulator FDZ86_RS01565 ENOG4105DC8 reductase FDZ86_RS01570 ENOG4105D6S protein involved in catabolism of external DNA FDZ86_RS01575 ENOG4105DGW oligopeptidase A FDZ86_RS01585 ENOG4105DUX Transporter FDZ86_RS01600 ENOG4105CJ3 phosphate transporter FDZ86_RS01605 ENOG4105CBX hi0933 family FDZ86_RS01610 ENOG4107UNS conserved inner membrane protein FDZ86_RS01625 ENOG4105D0S secretion protein (HlyD FDZ86_RS01630 ENOG4105CJ1 ABC, transporter FDZ86_RS01635 ENOG4105CMI transporter FDZ86_RS01650 ENOG4105D2N Aldolase FDZ86_RS01665 ENOG4105DT3 PTS system, galactitol-specific IIc component FDZ86_RS01670 ENOG41090UW PTS System FDZ86_RS01690 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS01695 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS01700 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FDZ86_RS01705 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FDZ86_RS01710 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FDZ86_RS01715 ENOG4107YAK holo-(acyl carrier protein) synthase 2 FDZ86_RS01720 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FDZ86_RS01725 ENOG4105C2D reductase FDZ86_RS01735 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FDZ86_RS01760 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) FDZ86_RS01790 ENOG4105E9Q Acyl-transferase FDZ86_RS01810 ENOG4105DSF transport protein FDZ86_RS01815 ENOG4105F9N Major Facilitator Superfamily FDZ86_RS01820 ENOG4108W1V Lipoprotein FDZ86_RS01825 ENOG4105EX9 Membrane FDZ86_RS01840 ENOG4107FS9 Membrane FDZ86_RS01850 ENOG4105MG3 Membrane FDZ86_RS01855 ENOG4106H78 methyltransferase FDZ86_RS01860 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FDZ86_RS01865 ENOG4105CAK Cell division ATP-binding protein ftsE FDZ86_RS01870 ENOG4105CRP Part of the ABC transporter FtsEX involved in FDZ86_RS01875 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FDZ86_RS01880 ENOG4105CP9 extracellular ligand-binding receptor FDZ86_RS01895 ENOG4105U59 -acetyltransferase FDZ86_RS01900 ENOG4105CP9 extracellular ligand-binding receptor FDZ86_RS01905 ENOG4105C32 Amino acid ABC transporter (Permease) FDZ86_RS01910 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FDZ86_RS01915 ENOG4105C0Z ABC transporter FDZ86_RS01920 ENOG4108IV0 ABC, transporter FDZ86_RS01930 ENOG4105BZ7 extracellular solute-binding protein family 1 FDZ86_RS01935 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component FDZ86_RS01940 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FDZ86_RS01945 ENOG4108IJ9 (ABC) transporter FDZ86_RS01950 ENOG4107T6V glycerophosphoryl diester phosphodiesterase FDZ86_RS01955 ENOG4105WC8 Conserved Protein FDZ86_RS01960 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FDZ86_RS01970 ENOG4105WCN acetyltransferase FDZ86_RS01975 ENOG4105D9R oxidoreductase FDZ86_RS01980 ENOG4105C2I pirin domain protein FDZ86_RS01985 ENOG4105DIQ Transcriptional regulator FDZ86_RS01990 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FDZ86_RS01995 ENOG4105C6Z Gluconate FDZ86_RS02000 ENOG4105C9U ATP-dependent DNA helicase RecQ FDZ86_RS02005 ENOG4105C9U ATP-dependent DNA helicase RecQ FDZ86_RS02020 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FDZ86_RS02025 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FDZ86_RS02030 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) FDZ86_RS02050 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FDZ86_RS02070 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FDZ86_RS02085 ENOG4105E98 transcriptional regulator DeoR family FDZ86_RS02090 ENOG4105CYB regulatoR FDZ86_RS02095 ENOG4105E0Y RtcB Protein FDZ86_RS02120 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FDZ86_RS02125 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) FDZ86_RS02130 ENOG4105C6Z Gluconate FDZ86_RS02140 ENOG4105MJ2 Competence protein FDZ86_RS02150 ENOG4105DNE Transposase FDZ86_RS02160 ENOG4105CE1 Ferrous iron transport protein b FDZ86_RS02165 ENOG4105XFK Ferrous iron transport protein A FDZ86_RS02170 ENOG4105BZM domain protein FDZ86_RS02175 ENOG4108RRZ Transcription elongation factor GreB FDZ86_RS02185 ENOG4105E0F Histidine kinase FDZ86_RS02195 ENOG4108MAJ Membrane FDZ86_RS02205 ENOG4105VEJ Heat shock protein FDZ86_RS02210 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FDZ86_RS02215 ENOG4105DQY intracellular growth attenuator FDZ86_RS02220 ENOG4107RK2 ADP-ribose diphosphatase NudE FDZ86_RS02225 ENOG4108JQC penicillin-binding protein 1A FDZ86_RS02230 ENOG4108U1Q Pilus assembly protein FDZ86_RS02235 ENOG41065NF Fimbrial assembly family protein FDZ86_RS02240 ENOG4105XPX DNA utilization protein HofO FDZ86_RS02245 ENOG4105ITY Required for the use of extracellular DNA as a nutrient FDZ86_RS02250 ENOG4105E4G Type IV pilus FDZ86_RS02265 ENOG4105EGB membrane protein DamX FDZ86_RS02270 ENOG4105DFE Dna adenine methylase FDZ86_RS02275 ENOG4105DJV ribulose-phosphate 3-epimerase FDZ86_RS02280 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FDZ86_RS02285 ENOG4105C31 Tryptophanyl-tRNA synthetase FDZ86_RS02290 ENOG4105FDP GntR family transcriptional regulator FDZ86_RS02300 ENOG4107Y0V Not clear, may be involved in an isomerization step FDZ86_RS02305 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine FDZ86_RS02310 ENOG4107QHQ amino acid FDZ86_RS02315 ENOG4105VYH FDZ86_RS02325 ENOG4107V9H nitrite transporter FDZ86_RS02330 ENOG4105WZK nitrite reductase NADPH small subunit FDZ86_RS02335 ENOG4107QZF nitrite reductase NADPH large subunit FDZ86_RS02345 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FDZ86_RS02355 ENOG4105MZU cell filamentation protein FDZ86_RS02360 ENOG4105DDQ anthranilate synthase FDZ86_RS02365 ENOG4105C8Y Acetylornithine aminotransferase FDZ86_RS02370 ENOG410613R integral membrane protein, YccS YhfK family FDZ86_RS02380 ENOG4108UKZ OsmC family FDZ86_RS02385 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) FDZ86_RS02395 ENOG4105DNZ Alpha Beta Hydrolase FDZ86_RS02400 ENOG4105C5H ABC transporter FDZ86_RS02415 ENOG4105VKU nucleicacid-binding protein FDZ86_RS02420 ENOG4108YZY peptidylprolyl cis-trans isomerase FDZ86_RS02430 ENOG4108V1T peptidylprolyl cis-trans isomerase FDZ86_RS02435 ENOG4105WWK YheO domain protein FDZ86_RS02475 ENOG4105W53 bacterioferritin-associated ferredoxin FDZ86_RS02480 ENOG4108UQY Iron-storage protein FDZ86_RS02505 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FDZ86_RS02550 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FDZ86_RS02595 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FDZ86_RS02600 ENOG41067V7 50S ribosomal protein L36 FDZ86_RS02630 ENOG4105VTS DnaJ-like, subfamily C FDZ86_RS02635 ENOG4105W1Y Transcriptional regulator FDZ86_RS02640 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system FDZ86_RS02650 ENOG4105C1A potassium transporter peripheral membrane FDZ86_RS02670 ENOG4105C79 DNA protecting protein DprA FDZ86_RS02680 ENOG4108WI1 Dna topoisomerase FDZ86_RS02685 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FDZ86_RS02695 ENOG4105SG3 Protein of unknown function (DUF1488) FDZ86_RS02700 ENOG4108Z0R Transferase FDZ86_RS02740 ENOG4105CDA abc transporter atp-binding protein FDZ86_RS02750 ENOG4105EZ7 amino acid ABC transporter FDZ86_RS02760 ENOG4105XCM membrane LIPOPROTEIN FDZ86_RS02770 ENOG4105C1P efflux transporter, rnd family, mfp subunit FDZ86_RS02775 ENOG4108XG4 DNA-binding transcriptional regulator FDZ86_RS02780 ENOG41061ME transport protein FDZ86_RS02785 ENOG4105CEC DNA methylase N-4 N-6 FDZ86_RS02795 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FDZ86_RS02805 ENOG4108IA2 Sodium pantothenate symporter FDZ86_RS02810 ENOG4105RG0 Membrane FDZ86_RS02815 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FDZ86_RS02820 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FDZ86_RS02825 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family FDZ86_RS02830 ENOG41062P1 Diguanylate cyclase phosphodiesterase FDZ86_RS02840 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FDZ86_RS02845 ENOG4105VQ7 Rod shape-determining protein MreD FDZ86_RS02850 ENOG4108Z03 MAF-like protein FDZ86_RS02855 ENOG4105C03 ribonuclease FDZ86_RS02860 ENOG4105QD6 exported protein FDZ86_RS02865 ENOG4105D1U peptidase U62 modulator of DNA gyrase FDZ86_RS02870 ENOG4105CR8 Transcriptional regulator FDZ86_RS02875 ENOG4105ZQC membrane protein AaeX FDZ86_RS02890 ENOG4105UNR (Barnase) inhibitor FDZ86_RS02895 ENOG4105RID UPF0379 protein yhcN FDZ86_RS02910 ENOG4105C0H protease FDZ86_RS02915 ENOG4105C0H protease FDZ86_RS02920 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III FDZ86_RS02925 ENOG4105D6Z AFG1 family ATPase FDZ86_RS02940 ENOG4107MKT Stringent starvation protein a FDZ86_RS02945 ENOG4105KB2 stringent starvation protein b FDZ86_RS02950 ENOG4105CEE C4-dicarboxylate transporter FDZ86_RS02980 ENOG4108R66 Conserved Protein FDZ86_RS02985 ENOG4105DFS Conserved Protein FDZ86_RS02990 ENOG4105BZ8 glutamate synthase FDZ86_RS02995 ENOG4105CBC glutamate synthase FDZ86_RS03000 ENOG4105N5T Radical SAM Protein FDZ86_RS03005 ENOG4105BZU Histidine kinase FDZ86_RS03010 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain FDZ86_RS03020 ENOG4108NIH transferase activity, transferring phosphorus-containing groups FDZ86_RS03025 ENOG41080Z8 PHOSPHOCARRIER protein FDZ86_RS03035 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN FDZ86_RS03040 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA FDZ86_RS03045 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FDZ86_RS03050 ENOG4108IUZ ABC transporter FDZ86_RS03055 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FDZ86_RS03060 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) FDZ86_RS03065 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase FDZ86_RS03070 ENOG4105C2X Arabinose 5-phosphate isomerase FDZ86_RS03075 ENOG4105FEU K -dependent Na -Ca exchanger FDZ86_RS03080 ENOG4105DHJ ABC, transporter FDZ86_RS03085 ENOG4105CY3 ABC transporter, permease FDZ86_RS03090 ENOG4107PE3 Mammalian cell entry related domain protein FDZ86_RS03095 ENOG4105E3I toluene tolerance FDZ86_RS03100 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane FDZ86_RS03105 ENOG4105VFK BolA family FDZ86_RS03115 ENOG4105HVQ Regulatory factor of maltose metabolism FDZ86_RS03120 ENOG4105EAH synthase FDZ86_RS03135 ENOG4105QYV Membrane FDZ86_RS03145 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase FDZ86_RS03150 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FDZ86_RS03155 ENOG4105HBR Rna-binding protein FDZ86_RS03165 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FDZ86_RS03170 ENOG4105EEI dihydropteroate synthase FDZ86_RS03180 ENOG4105NTZ Preprotein translocase subunit SecG FDZ86_RS03190 ENOG4105DIJ Phosphoethanolamine transferase FDZ86_RS03210 ENOG4105CHV Transcription elongation factor NusA FDZ86_RS03250 ENOG4105C1J atp-dependent rna helicase FDZ86_RS03255 ENOG4105CIC tryptophan-specific transport protein FDZ86_RS03260 ENOG4105DEN Luciferase family FDZ86_RS03280 ENOG4108YYD acetyltransferase FDZ86_RS03290 ENOG4108ZPB UPF0306 protein FDZ86_RS03295 ENOG4107R7Y intracellular protease Pfpi family FDZ86_RS03300 ENOG4105K4T epimerase FDZ86_RS03305 ENOG4107S21 permease FDZ86_RS03310 ENOG4105W4M Transport-associated protein FDZ86_RS03330 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FDZ86_RS03345 ENOG4105CW0 outer membrane usher protein FDZ86_RS03350 ENOG4108VCD Chaperone FDZ86_RS03355 ENOG4105Q10 Fimbrial-like protein FDZ86_RS03365 ENOG4105F3R pts system mannose fructose sorbose family iid FDZ86_RS03375 ENOG4108UZY PTS System FDZ86_RS03385 ENOG4105E70 isomerase FDZ86_RS03390 ENOG4105CE4 GlcNAc 6-P deacetylase FDZ86_RS03395 ENOG4108YTN IIa component FDZ86_RS03400 ENOG4105F3R pts system mannose fructose sorbose family iid FDZ86_RS03410 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB FDZ86_RS03420 ENOG4105E98 transcriptional regulator DeoR family FDZ86_RS03425 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression FDZ86_RS03430 ENOG4105ZEG Suppressor protein FDZ86_RS03435 ENOG4105CTX dehydratase FDZ86_RS03440 ENOG4105DJB Major Facilitator Superfamily FDZ86_RS03450 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FDZ86_RS03455 ENOG4105BZW Glycerate kinase FDZ86_RS03480 ENOG410811B TRANSCRIPTIONal FDZ86_RS03485 ENOG4105C7B Threonine dehydratase FDZ86_RS03495 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FDZ86_RS03500 ENOG4105C6N Formate acetyltransferase FDZ86_RS03505 ENOG4105KME endoribonuclease L-psp FDZ86_RS03510 ENOG4105EJQ L-serine dehydratase FDZ86_RS03515 ENOG4105C44 Serine transporter FDZ86_RS03525 ENOG4106D80 Uncharacterized protein YhaL FDZ86_RS03530 ENOG4108CNN domain protein FDZ86_RS03535 ENOG4105CWB LysR family transcriptional Regulator FDZ86_RS03540 ENOG4105KAF membrAne FDZ86_RS03545 ENOG4105KAF membrAne FDZ86_RS03550 ENOG4105CHF Glutathione S-transferase FDZ86_RS03555 ENOG4108VBZ doxx family FDZ86_RS03560 ENOG4105YJD FDZ86_RS03565 ENOG41090KG Inner membrane protein YqjE FDZ86_RS03570 ENOG4105NE1 Conserved Protein FDZ86_RS03575 ENOG4105WAY exported protein FDZ86_RS03580 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) FDZ86_RS03585 ENOG4106W5V Membrane FDZ86_RS03590 ENOG4107YCY Transcriptional regulator FDZ86_RS03595 ENOG4105DPW Major facilitator superfamily MFS_1 FDZ86_RS03605 ENOG4105CTX dehydratase FDZ86_RS03610 ENOG4105P66 Membrane FDZ86_RS03615 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) FDZ86_RS03620 ENOG4105DU1 integral membrane protein, terc FDZ86_RS03625 ENOG4105EE0 oxidoreductase FDZ86_RS03630 ENOG4108UB4 uncharacterized protein ygjQ FDZ86_RS03635 ENOG4108VKG metal-dependent hydrolase FDZ86_RS03645 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase FDZ86_RS03650 ENOG4108Z3N Transcriptional regulator FDZ86_RS03655 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDZ86_RS03660 ENOG4107WCA isomerase FDZ86_RS03665 ENOG4107W6W Conserved Protein FDZ86_RS03670 ENOG4105E5D amino acid FDZ86_RS03675 ENOG4105FK9 beta-D-galactosidase beta subunit FDZ86_RS03680 ENOG4105CNT hydrolase family 2 FDZ86_RS03685 ENOG4105CQ4 Transcriptional regulator FDZ86_RS03690 ENOG4108Y51 tRNA-binding protein FDZ86_RS03700 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor FDZ86_RS03705 ENOG4105NTW Transcriptional regulator FDZ86_RS03710 ENOG4105Q26 Siderophore-interacting protein FDZ86_RS03725 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FDZ86_RS03730 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FDZ86_RS03745 ENOG4107QPK )-transporter FDZ86_RS03750 ENOG4107GFK fumarate FDZ86_RS03755 ENOG4106DSS Tartrate dehydratase subunit alpha FDZ86_RS03760 ENOG4105EJC lysr family transcriptional regulator FDZ86_RS03770 ENOG4107ZVW dihydroneopterin aldolase FDZ86_RS03785 ENOG4106MWK domain protein FDZ86_RS03790 ENOG4105I7R Adenylate cyclase FDZ86_RS03815 ENOG4107S78 Band 7 protein FDZ86_RS03820 ENOG4105PV3 Inner membrane protein yqiJ FDZ86_RS03830 ENOG4105W0Z cytoplasmic protein FDZ86_RS03850 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FDZ86_RS03855 ENOG4106032 Glutathionylspermidine synthase FDZ86_RS03865 ENOG4105DFG type I secretion outer membrane protein FDZ86_RS03870 ENOG41087AY ADP-Ribose pyrophosphatase FDZ86_RS03875 ENOG4108SX3 cytoplasmic protein FDZ86_RS03880 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FDZ86_RS03885 ENOG4105IPS esterase FDZ86_RS03890 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDZ86_RS03900 ENOG4105E0A ABC, transporter FDZ86_RS03905 ENOG4105DQ5 transport system permease protein FDZ86_RS03910 ENOG4105EHG Permease protein FDZ86_RS03920 ENOG4106KNT transcriptional regulator FDZ86_RS03925 ENOG4105VRH Antibiotic biosynthesis monooxygenase FDZ86_RS03930 ENOG4105NF4 modulator of drug activity FDZ86_RS03935 ENOG4105DHQ Histidine kinase FDZ86_RS03940 ENOG4105XJC Two component transcriptional regulator (Winged helix family FDZ86_RS03945 ENOG4105H4F exported protein FDZ86_RS03950 ENOG4105F4I Transcriptional regulator FDZ86_RS03955 ENOG4108J59 Extracellular solute-binding protein, family 5 FDZ86_RS03960 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDZ86_RS03965 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase FDZ86_RS03970 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) FDZ86_RS03975 ENOG4105CCT upf0313 protein FDZ86_RS03990 ENOG4105CV8 reductase FDZ86_RS03995 ENOG4108I6A alcohol dehydrogenase FDZ86_RS04000 ENOG4105CF7 AraC family transcriptional regulator FDZ86_RS04005 ENOG4108K81 inner membrane protein YghB FDZ86_RS04010 ENOG4105C28 cystathionine FDZ86_RS04015 ENOG4105CWK Biopolymer transport protein, ExbB FDZ86_RS04020 ENOG4108ZZF transport protein (ExbD) FDZ86_RS04025 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FDZ86_RS04035 ENOG4105CPC Aldo Keto reductase FDZ86_RS04045 ENOG410900S Protein of unknown function (DUF2623) FDZ86_RS04050 ENOG4105E3S small subunit FDZ86_RS04055 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FDZ86_RS04060 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit FDZ86_RS04065 ENOG4105DPX Hydrogenase, large subunit FDZ86_RS04070 ENOG4108USZ hydrogenase FDZ86_RS04075 ENOG4108WGS hydrogenase 2-specific chaperone FDZ86_RS04080 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FDZ86_RS04085 ENOG41082MF Hydrogenase assembly chaperone hypC hupF FDZ86_RS04090 ENOG4105CYM Glutathione S-transferase FDZ86_RS04095 ENOG4106032 Glutathionylspermidine synthase FDZ86_RS04120 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS04125 ENOG4105E5H Transposase FDZ86_RS04130 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS04180 ENOG4105H38 Membrane FDZ86_RS04195 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS04220 ENOG4108UQV Membrane FDZ86_RS04225 ENOG4105CXN decarboxylase FDZ86_RS04230 ENOG4105EAA nucleoside FDZ86_RS04245 ENOG4105CEN a g-specific adenine glycosylase FDZ86_RS04255 ENOG41090ED Protein with unknown function (DUF469) FDZ86_RS04260 ENOG4105K33 Periplasmic Protein FDZ86_RS04265 ENOG4105HDK L-asparaginase FDZ86_RS04270 ENOG4106MH3 alpha helix chain FDZ86_RS04275 ENOG4105CSA Coproporphyrinogen iii oxidase FDZ86_RS04280 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FDZ86_RS04290 ENOG4108VIA integral membrane protein FDZ86_RS04295 ENOG4105DFA alanine racemase domain protein FDZ86_RS04300 ENOG4105CZX twitching motility protein FDZ86_RS04315 ENOG4105D7Z glutathione synthase FDZ86_RS04320 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FDZ86_RS04325 ENOG4105RWS endonuclease I FDZ86_RS04330 ENOG4105GPY SprT protein FDZ86_RS04335 ENOG4107QNK )-transporter FDZ86_RS04355 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) FDZ86_RS04370 ENOG4108K0D peptidase, M48 FDZ86_RS04375 ENOG4105CV1 Transketolase (EC 2.2.1.1) FDZ86_RS04380 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia FDZ86_RS04385 ENOG4105CTS PTS system mannitol-specific FDZ86_RS04390 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FDZ86_RS04395 ENOG4108Q8A Fructose-1,6-bisphosphatase FDZ86_RS04400 ENOG4108R4K DNA-binding, transcriptional regulator FDZ86_RS04405 ENOG4107Z1W Fructose transport system kinase FDZ86_RS04410 ENOG4108JJB ABC transporter FDZ86_RS04415 ENOG4108JJB ABC transporter FDZ86_RS04440 ENOG4105BZA Phosphoglycerate kinase FDZ86_RS04445 ENOG4105D2N Aldolase FDZ86_RS04450 ENOG4105D64 Mechanosensitive ion channel FDZ86_RS04455 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FDZ86_RS04460 ENOG4105MPN Membrane FDZ86_RS04470 ENOG4105CYC Transferase FDZ86_RS04480 ENOG4105DJT lAO AO transport system ATPase FDZ86_RS04485 ENOG4105D5P Methylmalonyl-coA mutase FDZ86_RS04500 ENOG4108JQ1 Dehydrogenase FDZ86_RS04515 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FDZ86_RS04535 ENOG4107RAQ aminopeptidase FDZ86_RS04540 ENOG4105D0A hydroxylase FDZ86_RS04545 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FDZ86_RS04570 ENOG4105CS2 ec 3.2.1.21 FDZ86_RS04575 ENOG4105N5Z UPF0267 protein FDZ86_RS04580 ENOG4108UT2 hemolysin iii FDZ86_RS04590 ENOG4105Y75 tpr repeat protein FDZ86_RS04595 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB FDZ86_RS04600 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) FDZ86_RS04605 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FDZ86_RS04610 ENOG4105T95 Thiol disulfide interChange protein FDZ86_RS04615 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FDZ86_RS04625 ENOG4105CRK lysyL-tRNA synthetase FDZ86_RS04645 ENOG4105C2W permease FDZ86_RS04650 ENOG4105BZ8 glutamate synthase FDZ86_RS04660 ENOG4105C7N Xanthine uracil vitamin C permease FDZ86_RS04665 ENOG4107QUY Guanine deaminase FDZ86_RS04670 ENOG4105C2W permease FDZ86_RS04675 ENOG4105C7W Xanthine dehydrogenase FDZ86_RS04680 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase FDZ86_RS04685 ENOG4107UUR Chlorohydrolase aminohydrolase FDZ86_RS04690 ENOG4105BZ8 glutamate synthase FDZ86_RS04695 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase FDZ86_RS04700 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC FDZ86_RS04705 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FDZ86_RS04710 ENOG4105C5B carbamate kinase FDZ86_RS04720 ENOG4107S4Y M20 DapE family protein YgeY FDZ86_RS04725 ENOG4107RCH Diaminopropionate ammonia-lyase FDZ86_RS04730 ENOG4105IW6 Carbamoyltransferase FDZ86_RS04735 ENOG4108JUB Transcriptional regulator FDZ86_RS04740 ENOG4108UTP (2Fe-2S)-binding domain protein FDZ86_RS04745 ENOG4108HR6 Dehydrogenase FDZ86_RS04750 ENOG4105C7W Xanthine dehydrogenase FDZ86_RS04755 ENOG4108K5P (LipO)protein FDZ86_RS04775 ENOG41090HZ type iii secretion FDZ86_RS04785 ENOG4108N8R Invasion protein FDZ86_RS04790 ENOG4108HR8 type iii secretion FDZ86_RS04795 ENOG4108JIR Flagellum-specific ATP synthase FDZ86_RS04810 ENOG4105T85 surface presentation of antigens protein FDZ86_RS04815 ENOG41075IY surface presentation of antigens protein SpaP FDZ86_RS04820 ENOG4105U07 type iii secretion FDZ86_RS04830 ENOG4108M6W surface presentation of antigens protein SpaS FDZ86_RS04850 ENOG4105Y7Q type iii secretion FDZ86_RS04855 ENOG4106BTR FDZ86_RS04860 ENOG4108RBT type iii secretion FDZ86_RS04885 ENOG4105K5T PilT protein FDZ86_RS04895 ENOG4108YAB Invasion protein FDZ86_RS04925 ENOG4105FV3 FDZ86_RS04930 ENOG4108TC1 Transcriptional regulator FDZ86_RS04935 ENOG4105ISV protein with bipartite regulator domain FDZ86_RS04940 ENOG4108MHD transport protein FDZ86_RS04945 ENOG4105CHU acetyl-coa acetyltransferase FDZ86_RS04955 ENOG4105CHR reductase FDZ86_RS04960 ENOG4107QNK )-transporter FDZ86_RS04970 ENOG4105RQF LysR family Transcriptional regulator FDZ86_RS04980 ENOG41060NJ transcriptional regulator FDZ86_RS04995 ENOG4105CPC Aldo Keto reductase FDZ86_RS05000 ENOG4105SUV lipoprotein YgdR FDZ86_RS05005 ENOG4105EE5 Membrane protein terC FDZ86_RS05020 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FDZ86_RS05035 ENOG4105IPU prepilin peptidase dependent protein A FDZ86_RS05040 ENOG4105JCS prepilin peptidase dependent protein FDZ86_RS05045 ENOG4105SEN Protein of unknown function (DUF2509) FDZ86_RS05050 ENOG4105RVB Prepilin peptidase dependent protein c FDZ86_RS05055 ENOG4105DSY exodeoxyribonuclease V, gamma FDZ86_RS05060 ENOG4107QXK peptidase FDZ86_RS05065 ENOG4107QKA exodeoxyribonuclease V beta FDZ86_RS05070 ENOG4107QYX exodeoxyribonuclease v alpha FDZ86_RS05075 ENOG4108EKC n-acetylglutamate synthase FDZ86_RS05080 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FDZ86_RS05100 ENOG4105CA3 membrane-bound lytic murein transglycosylase FDZ86_RS05105 ENOG4105CUZ uba thif-type nad fad binding protein FDZ86_RS05110 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) FDZ86_RS05115 ENOG4105C9B Cysteine desulfurase FDZ86_RS05120 ENOG4105M5B (LipO)protein FDZ86_RS05125 ENOG4105ETT transcriptional Regulator, LysR family FDZ86_RS05130 ENOG4105M08 Membrane FDZ86_RS05140 ENOG4107EDW L-fucose operon activator FDZ86_RS05150 ENOG4105CMG Carbohydrate kinase FDZ86_RS05160 ENOG4105EDR glucose galactose transporter FDZ86_RS05165 ENOG4107W7X Aldolase FDZ86_RS05170 ENOG4105C0A alcohol dehydrogenase FDZ86_RS05180 ENOG4105EJQ L-serine dehydratase FDZ86_RS05185 ENOG4105C44 Serine transporter FDZ86_RS05190 ENOG4105EWT decarboxylase family FDZ86_RS05205 ENOG4105WP7 tRNA pseudouridine synthase C FDZ86_RS05210 ENOG4105DR9 pseudouridine synthase FDZ86_RS05215 ENOG4105QDK Flavodoxin FDZ86_RS05220 ENOG4105DJB Major Facilitator Superfamily FDZ86_RS05230 ENOG4105EQX glucarate dehydratase FDZ86_RS05235 ENOG4105BZU Histidine kinase FDZ86_RS05240 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FDZ86_RS05245 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FDZ86_RS05250 ENOG4106A2Z transcriptional regulator antitoxin, MazE FDZ86_RS05255 ENOG4105MZG transcriptional modulator of maze toxin, mazf FDZ86_RS05260 ENOG4105DXN mazG family FDZ86_RS05275 ENOG4105HA9 of methanol dehydrogenase type FDZ86_RS05285 ENOG4105HA9 of methanol dehydrogenase type FDZ86_RS05295 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FDZ86_RS05300 ENOG4108CWB sugar kinase ygcE FDZ86_RS05305 ENOG4108ITV Inner membrane protein yqcE FDZ86_RS05310 ENOG4105CHR reductase FDZ86_RS05325 ENOG4106IKH Electron transfer flavoprotein FDZ86_RS05335 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FDZ86_RS05340 ENOG4105WQV ferredoxin-like protein FDZ86_RS05345 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FDZ86_RS05350 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FDZ86_RS05355 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FDZ86_RS05370 ENOG4107635 Hok Gef family protein FDZ86_RS05375 ENOG4105DTT CRISPR-associated helicase, cas3 FDZ86_RS05380 ENOG4105CYR Crispr-associated protein, cse1 family FDZ86_RS05390 ENOG41060M0 Crispr-associated protein, cse4 family FDZ86_RS05395 ENOG4108VWQ crispr-associated protein FDZ86_RS05405 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) FDZ86_RS05410 ENOG4105PWE CRISPR-associated protein cas2 FDZ86_RS05415 ENOG4108MXK alkaline phosphatase isozyme conversion FDZ86_RS05435 ENOG4105N0Z inner membrane protein ygbE FDZ86_RS05470 ENOG4108K5P (LipO)protein FDZ86_RS05475 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FDZ86_RS05480 ENOG4105PX9 Transcriptional regulator, MarR family FDZ86_RS05485 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FDZ86_RS05490 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FDZ86_RS05495 ENOG4105KZM cytoplasmic protein FDZ86_RS05500 ENOG4105MEW serine threonine protein phosphatase FDZ86_RS05515 ENOG4105VXR cytoplasmic protein FDZ86_RS05520 ENOG4108JUA Transcriptional regulator FDZ86_RS05525 ENOG4105C45 hydrogenase expression formation protein (HypE) FDZ86_RS05530 ENOG4105CQS hydrogenase expression formation protein HypD FDZ86_RS05535 ENOG41083WG hydrogenase assembly chaperone FDZ86_RS05540 ENOG4107RSS Hydrogenase accessory protein HypB FDZ86_RS05545 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FDZ86_RS05550 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA FDZ86_RS05555 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FDZ86_RS05560 ENOG4107R30 NADH dehydrogenase FDZ86_RS05565 ENOG4107TDF Formate hydrogenlyase subunit 4 FDZ86_RS05570 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FDZ86_RS05575 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit FDZ86_RS05580 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FDZ86_RS05585 ENOG4105I6X formate hydrogenlyase maturation FDZ86_RS05590 ENOG4108MG9 hydrogenase 3 maturation protease FDZ86_RS05595 ENOG4105CS2 ec 3.2.1.21 FDZ86_RS05600 ENOG4105C5Y PTS System FDZ86_RS05605 ENOG4105DDV Transcriptional regulator (LacI family FDZ86_RS05610 ENOG4108RC0 Electron transport protein FDZ86_RS05615 ENOG4105C8H hydrogenase maturation protein Hypf FDZ86_RS05635 ENOG4105C2X Arabinose 5-phosphate isomerase FDZ86_RS05640 ENOG410804X Transcriptional regulator FDZ86_RS05645 ENOG4105J92 DNA-binding transcriptional activator GutM FDZ86_RS05650 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase FDZ86_RS05655 ENOG4105VI0 Pts system, glucitol sorbitol-specific FDZ86_RS05670 ENOG4105CVE Lytic murein transglycosylase FDZ86_RS05675 ENOG4107TH8 cina domain protein FDZ86_RS05690 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FDZ86_RS05695 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FDZ86_RS05725 ENOG4107VXZ Hydrolase FDZ86_RS05730 ENOG4105W39 Membrane FDZ86_RS05745 ENOG4105C0R drug resistance transporter emrb qaca subfamily FDZ86_RS05750 ENOG4105CW7 secretion protein, HlyD family FDZ86_RS05755 ENOG4105NTK Transcriptional repressor Mpra FDZ86_RS05760 ENOG4105ZED uncharacterized protein ygaH FDZ86_RS05765 ENOG4108UMN azlc family FDZ86_RS05770 ENOG4105EQ0 Major Facilitator superfamily FDZ86_RS05775 ENOG4105GIJ Glycine betaine FDZ86_RS05780 ENOG4108HQS Glycine betaine FDZ86_RS05785 ENOG4108IJ7 Glycine betaine FDZ86_RS05790 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FDZ86_RS05795 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FDZ86_RS05805 ENOG4105WAZ (Glutaredoxin-like protein) NrdH FDZ86_RS05810 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FDZ86_RS05820 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) FDZ86_RS05825 ENOG4108WMJ Protein of unknown function (DUF2002) FDZ86_RS05830 ENOG4108RNS Exports L-alanine (By similarity) FDZ86_RS05835 ENOG4108X73 DNA- binding protein FDZ86_RS05840 ENOG4108V62 Rhodanese domain protein FDZ86_RS05845 ENOG41080HT Transcriptional regulator, arsr family FDZ86_RS05850 ENOG4105VPI YqaE family transport protein FDZ86_RS05855 ENOG4109066 lysm domain bon superfamily protein FDZ86_RS05860 ENOG4108PVQ transcriptional regulator FDZ86_RS05865 ENOG4105C85 amino acid FDZ86_RS05870 ENOG4108JPW Aminotransferase FDZ86_RS05875 ENOG4105C26 Dehydrogenase FDZ86_RS05880 ENOG4105D5U fad dependent oxidoreductase FDZ86_RS05980 ENOG4108R1E Serine threonine protein phosphatase 1 FDZ86_RS06005 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS06025 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS06070 ENOG4106FE3 DNA repair FDZ86_RS06085 ENOG4108Z1B Cyclase dehydrase FDZ86_RS06095 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FDZ86_RS06100 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FDZ86_RS06115 ENOG4108JU6 CBS domain protein FDZ86_RS06120 ENOG4106KVJ cytochrome C assembly protein FDZ86_RS06125 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FDZ86_RS06150 ENOG41090EK ompa motb domain protein FDZ86_RS06155 ENOG4108KHX Diguanylate cyclase FDZ86_RS06160 ENOG4108WS1 FDZ86_RS06165 ENOG4105QP9 Protein of unknown function (DUF2799) FDZ86_RS06170 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FDZ86_RS06175 ENOG4105EHE chorismate mutase- prephenate dehydrogenase FDZ86_RS06180 ENOG4105CQC Prephenate dehydratase FDZ86_RS06190 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA FDZ86_RS06195 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FDZ86_RS06200 ENOG4105C34 Pseudouridine synthase FDZ86_RS06205 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FDZ86_RS06210 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FDZ86_RS06235 ENOG4105CSH Transporter FDZ86_RS06240 ENOG4105T42 (LipO)protein FDZ86_RS06245 ENOG4105JIM Phosphatidylserine synthase FDZ86_RS06250 ENOG4105CD5 CoA-binding domain protein FDZ86_RS06255 ENOG4106IUH DTW domain containing protein FDZ86_RS06260 ENOG4105K63 Thioredoxin FDZ86_RS06265 ENOG4105EIB trna rrna methyltransferase FDZ86_RS06280 ENOG4108VP3 Lysine exporter protein (LysE YggA) FDZ86_RS06285 ENOG41090KR LysR family transcriptional Regulator FDZ86_RS06290 ENOG4105C1J atp-dependent rna helicase FDZ86_RS06295 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) FDZ86_RS06300 ENOG4108IYU L-aspartate oxidase FDZ86_RS06310 ENOG4105EMN RNA polymerase sigma factor FDZ86_RS06315 ENOG41069PW sigma-e factor negative regulatory protein FDZ86_RS06320 ENOG4105VQK sigma E regulatory protein, MucB RseB FDZ86_RS06325 ENOG4105WMJ Positive regulator of sigma E, RseC MucC FDZ86_RS06335 ENOG4105C3F Signal peptidase i FDZ86_RS06355 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FDZ86_RS06370 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FDZ86_RS06375 ENOG4106G6Q Transcriptional regulator FDZ86_RS06380 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB FDZ86_RS06385 ENOG4108Z6B deaminase FDZ86_RS06390 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) FDZ86_RS06395 ENOG4108ETH Formylglycinamide ribotide synthetase FDZ86_RS06400 ENOG4107WP9 Histidine kinase FDZ86_RS06405 ENOG4108SKK alpha helix protein FDZ86_RS06410 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FDZ86_RS06420 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FDZ86_RS06445 ENOG4107HQ7 repeat protein FDZ86_RS06450 ENOG4105FCA ABC transporter periplasmic-binding protein YphF FDZ86_RS06455 ENOG4108F37 ATP-binding component of a transport system FDZ86_RS06460 ENOG4105CNN ABC, transporter FDZ86_RS06465 ENOG4105CPQ Dehydrogenase FDZ86_RS06470 ENOG4105CPQ Dehydrogenase FDZ86_RS06475 ENOG4108ZKT aldose 1-epimerase FDZ86_RS06480 ENOG4108SB3 DoxX Family FDZ86_RS06505 ENOG4105FUY alpha subunit FDZ86_RS06510 ENOG4108W5M transcriptional regulator FDZ86_RS06515 ENOG4105D8G Major Facilitator superfamily FDZ86_RS06520 ENOG4108MN2 Stationary phase inducible protein CsiE FDZ86_RS06525 ENOG4107XM9 (LipO)protein FDZ86_RS06530 ENOG4105ECY inositol monophosphatase FDZ86_RS06550 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FDZ86_RS06570 ENOG4108ZIT Ferredoxin, 2FE-2S FDZ86_RS06575 ENOG4105WVQ Fe-S assembly protein IscX FDZ86_RS06585 ENOG4105YYA enhanced serine sensitivity protein SseB FDZ86_RS06590 ENOG4105KHC sulfurtransferase FDZ86_RS06595 ENOG4105DN3 alpha-2-macroglobulin domain protein FDZ86_RS06600 ENOG4108JQB penicillin-binding protein 1C FDZ86_RS06605 ENOG4107QY8 reductase FDZ86_RS06610 ENOG4105QAX Iron-sulfur FDZ86_RS06615 ENOG4107KGK dmso reductase anchor subunit FDZ86_RS06650 ENOG4105N21 Membrane FDZ86_RS06665 ENOG4105VPD cellular component movement FDZ86_RS06675 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FDZ86_RS06685 ENOG41066DY Membrane FDZ86_RS06690 ENOG4108ZMA Outer membrane lipoprotein FDZ86_RS06695 ENOG41062G3 Protein of unknown function (DUF2633) FDZ86_RS06705 ENOG4105BZU Histidine kinase FDZ86_RS06710 ENOG4105C9X ppx gppa phosphatase FDZ86_RS06715 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FDZ86_RS06720 ENOG4108V3E phosphoribosylglycinamide formyltransferase FDZ86_RS06735 ENOG4105C2W permease FDZ86_RS06740 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) FDZ86_RS06745 ENOG4105K89 arsenate reductase FDZ86_RS06750 ENOG4105ERG peptidase m48, ste24p FDZ86_RS06755 ENOG4105C02 permease FDZ86_RS06760 ENOG4105TMB Formate nitrite transporter FDZ86_RS06765 ENOG4108JUA Transcriptional regulator FDZ86_RS06770 ENOG4105I6X formate hydrogenlyase maturation FDZ86_RS06775 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FDZ86_RS06785 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FDZ86_RS06790 ENOG4108JPZ Monovalent cation H antiporter subunit D FDZ86_RS06795 ENOG4107WQX hydrogenase 4 membrane subunit FDZ86_RS06800 ENOG4105D65 subunit l FDZ86_RS06805 ENOG4107TDF Formate hydrogenlyase subunit 4 FDZ86_RS06810 ENOG4108JPZ Monovalent cation H antiporter subunit D FDZ86_RS06815 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FDZ86_RS06820 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FDZ86_RS06825 ENOG4105RH4 Glycine cleavage system transcriptional repressor FDZ86_RS06835 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FDZ86_RS06845 ENOG4105CGZ zinc metallopeptidase FDZ86_RS06855 ENOG4106KED esterase YpfH FDZ86_RS06870 ENOG4105KUZ arsenate reductase FDZ86_RS06880 ENOG4105BZS acriflavin resistance protein FDZ86_RS06885 ENOG4105BZU Histidine kinase FDZ86_RS06890 ENOG4105BZ8 glutamate synthase FDZ86_RS06900 ENOG4108PVD exported protein FDZ86_RS06905 ENOG4105CV1 Transketolase (EC 2.2.1.1) FDZ86_RS06910 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FDZ86_RS06915 ENOG4105C6K Malic enzyme FDZ86_RS06920 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place FDZ86_RS06925 ENOG4106S4J ethanolamine utilization protein EutP FDZ86_RS06930 ENOG4105NDK ethanolamine utilization protein FDZ86_RS06935 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase FDZ86_RS06940 ENOG4107WUY phosphate acetyltransferase FDZ86_RS06945 ENOG4105KNY Microcompartments protein FDZ86_RS06950 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml FDZ86_RS06955 ENOG4108EKI Dehydrogenase FDZ86_RS06960 ENOG4107RWI ethanolamine utilization protein eutJ FDZ86_RS06965 ENOG4105C0A alcohol dehydrogenase FDZ86_RS06970 ENOG4105ENY Ethanolamine utilization protein eutH FDZ86_RS06975 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase FDZ86_RS06980 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase FDZ86_RS06985 ENOG4105CPD ethanolamine ammonia-lyase FDZ86_RS06995 ENOG4106D67 ethanolamine utilization protein FDZ86_RS07000 ENOG4108X49 Ethanolamine utilization protein EutK FDZ86_RS07005 ENOG4108K3Z AraC family transcriptional regulator FDZ86_RS07015 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase FDZ86_RS07025 ENOG4105QZU Inner membrane protein YfeZ FDZ86_RS07030 ENOG4105E7K (LipO)protein FDZ86_RS07035 ENOG4105EZR dyp-type peroxidase family protein FDZ86_RS07040 ENOG4107QK9 Beta-lactamase FDZ86_RS07045 ENOG4105C5Y PTS System FDZ86_RS07060 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FDZ86_RS07065 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein FDZ86_RS07070 ENOG4108I5D sulfate abc transporter FDZ86_RS07075 ENOG4105ECW sulfate abc transporter FDZ86_RS07080 ENOG4108IJ6 ABC transporter FDZ86_RS07085 ENOG4105C6T cysteine synthase FDZ86_RS07100 ENOG4105C5Y PTS System FDZ86_RS07105 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FDZ86_RS07115 ENOG4105C6T cysteine synthase FDZ86_RS07135 ENOG4105VRT cytoplasmic protein FDZ86_RS07140 ENOG4105DHU Bile acid FDZ86_RS07145 ENOG4108M0I Transcriptional regulator FDZ86_RS07185 ENOG4105D7V transposase FDZ86_RS07190 ENOG4105GXM Putative transcription regulator (DUF1323) FDZ86_RS07195 ENOG4105HZG regulatoR FDZ86_RS07210 ENOG4108KMM Diguanylate cyclase FDZ86_RS07215 ENOG4105D9N nucleoside FDZ86_RS07225 ENOG4109076 Conserved Protein FDZ86_RS07230 ENOG4105VCT ion-transport protein YfeO FDZ86_RS07240 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) FDZ86_RS07245 ENOG410863U PTS System FDZ86_RS07250 ENOG4105DC7 peptidase M24 FDZ86_RS07255 ENOG4105CN9 Peptidase m42 family protein FDZ86_RS07260 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FDZ86_RS07265 ENOG4108CIP transcriptional regulator FDZ86_RS07270 ENOG4105DY9 regulatoR FDZ86_RS07275 ENOG4108HRK Histidine kinase FDZ86_RS07280 ENOG4105CHM Aminotransferase FDZ86_RS07290 ENOG4105D1S lipid A biosynthesis FDZ86_RS07295 ENOG4105W9M Membrane FDZ86_RS07305 ENOG4108V08 YfdX protein FDZ86_RS07315 ENOG4105CFN oxalyl-CoA decarboxylase FDZ86_RS07320 ENOG4108N2Y auxin Efflux FDZ86_RS07325 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FDZ86_RS07330 ENOG4105BZU Histidine kinase FDZ86_RS07335 ENOG4108WQH regulatoR FDZ86_RS07340 ENOG4105CW7 secretion protein, HlyD family FDZ86_RS07345 ENOG4105C0R drug resistance transporter emrb qaca subfamily FDZ86_RS07360 ENOG4106NDP Transcriptional regulator FDZ86_RS07365 ENOG4108HKT sucrose-6-phosphate hydrolase FDZ86_RS07370 ENOG4105D7K pfkb domain protein FDZ86_RS07375 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FDZ86_RS07420 ENOG4105DFP Integrase FDZ86_RS07430 ENOG4105S64 Formate nitrite transporter FDZ86_RS07435 ENOG410903C (LipO)protein FDZ86_RS07445 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation FDZ86_RS07450 ENOG4105KZW UPF0381 protein FDZ86_RS07465 ENOG4108BY2 phosphohistidine phosphatase FDZ86_RS07475 ENOG4106PG1 outer membrane usher protein FDZ86_RS07480 ENOG4108FZ9 Chaperone FDZ86_RS07485 ENOG4105NEV Fimbrial FDZ86_RS07490 ENOG4105UGQ Fimbrial FDZ86_RS07495 ENOG4105US4 fimbrial-like protein yfcP FDZ86_RS07515 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase FDZ86_RS07525 ENOG4105EJ9 Membrane FDZ86_RS07530 ENOG4108BPE -transporting atpase FDZ86_RS07535 ENOG4105MH2 YfcL protein FDZ86_RS07540 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) FDZ86_RS07545 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FDZ86_RS07550 ENOG4105F9N Major Facilitator Superfamily FDZ86_RS07555 ENOG4106WZ1 flagella biosynthesis regulator FDZ86_RS07565 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FDZ86_RS07575 ENOG4105DQR SNARE associated Golgi FDZ86_RS07585 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FDZ86_RS07590 ENOG4108S3P Sporulation domain protein FDZ86_RS07595 ENOG4105E96 Colicin v production protein FDZ86_RS07600 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FDZ86_RS07605 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FDZ86_RS07610 ENOG4105E89 ABC transporter FDZ86_RS07615 ENOG4105E89 ABC transporter FDZ86_RS07620 ENOG4105DSP amino acid AbC transporter FDZ86_RS07625 ENOG4106YG3 ABC transporter FDZ86_RS07630 ENOG4108JEH abc transporter atp-binding protein FDZ86_RS07635 ENOG4105DNE Transposase FDZ86_RS07640 ENOG4105ECP epimerase FDZ86_RS07645 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase FDZ86_RS07650 ENOG4105CYM Glutathione S-transferase FDZ86_RS07655 ENOG4108SHQ Glutathione S-transferase FDZ86_RS07660 ENOG4108RE9 Phosphodiesterase FDZ86_RS07665 ENOG4105PTV Nudix Hydrolase FDZ86_RS07670 ENOG4105CSX c4-dicarboxylate anaerobic carrier FDZ86_RS07675 ENOG4105C6K Malic enzyme FDZ86_RS07680 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FDZ86_RS07690 ENOG4105XWI UPF0304 protein FDZ86_RS07695 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 FDZ86_RS07700 ENOG4107QWE )-transporter FDZ86_RS07710 ENOG4105CHM Aminotransferase FDZ86_RS07715 ENOG4107NQ8 LysR family Transcriptional regulator FDZ86_RS07735 ENOG4105GKE subunit e FDZ86_RS07740 ENOG4107QIZ NADH dehydrogenase FDZ86_RS07745 ENOG4108IEH NADH dehydrogenase subunit g FDZ86_RS07760 ENOG4107UFS subunit j FDZ86_RS07770 ENOG4105D65 subunit l FDZ86_RS07775 ENOG4105C8S subunit m FDZ86_RS07785 ENOG4105GDX Domain of unknown function (DUF1877) FDZ86_RS07800 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is FDZ86_RS07805 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FDZ86_RS07810 ENOG4107YB6 acetyltransferase, (GNAT) family FDZ86_RS07815 ENOG4105TNS Conserved Protein FDZ86_RS07820 ENOG4105E4F Isochorismate synthase FDZ86_RS07835 ENOG4108IPT Naphthoate synthase FDZ86_RS07845 ENOG4105CEY Amp-dependent synthetase and ligase FDZ86_RS07850 ENOG4106GZG polymyxin resistance protein B FDZ86_RS07890 ENOG4108WMR Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core (By similarity) FDZ86_RS07900 ENOG4108UII YfaZ family FDZ86_RS07905 ENOG4108EWA cinA-like protein FDZ86_RS07910 ENOG4107258 Transcriptional regulator FDZ86_RS07915 ENOG4105CXK mandelate racemase muconate lactonizing FDZ86_RS07920 ENOG4105CSP Major Facilitator Superfamily FDZ86_RS07925 ENOG4105CNV Aldolase FDZ86_RS07930 ENOG4105DNE Transposase FDZ86_RS07935 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FDZ86_RS07945 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A FDZ86_RS07950 ENOG4105CXY transporter FDZ86_RS07965 ENOG4105GZI Transcriptional regulator FDZ86_RS07970 ENOG4105CZM Major Facilitator FDZ86_RS07975 ENOG4105FQR PH-inducible protein involved in stress response FDZ86_RS07980 ENOG4105XPH Ferredoxin FDZ86_RS07985 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FDZ86_RS07990 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FDZ86_RS07995 ENOG4107GHC outer membrane autotransporter FDZ86_RS08005 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDZ86_RS08010 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) FDZ86_RS08015 ENOG4108QJJ Protein of unknown function (DUF1175) FDZ86_RS08020 ENOG4107S52 alpha-2-macroglobulin domain protein FDZ86_RS08025 ENOG41081SK signal peptide protein FDZ86_RS08030 ENOG41081SK signal peptide protein FDZ86_RS08035 ENOG4105EDV vault protein FDZ86_RS08040 ENOG4105BZU Histidine kinase FDZ86_RS08045 ENOG41068CG regulatoR FDZ86_RS08050 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC FDZ86_RS08055 ENOG4105FCK Membrane FDZ86_RS08060 ENOG4105CJ2 (LipO)protein FDZ86_RS08065 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FDZ86_RS08070 ENOG4105CF1 Alkylated DNA repair protein FDZ86_RS08075 ENOG4105IBP Cyclic peptide transporter FDZ86_RS08090 ENOG4108ZNS ferredoxin-type protein NapF FDZ86_RS08095 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase FDZ86_RS08105 ENOG4108BGM Quinol dehydrogenase periplasmic component FDZ86_RS08110 ENOG4105GXZ Ferredoxin-type protein NapH FDZ86_RS08115 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) FDZ86_RS08120 ENOG4105CUW cytochrome C-TYPE protein FDZ86_RS08125 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS08130 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) FDZ86_RS08135 ENOG41060IM Heme exporter protein FDZ86_RS08140 ENOG4105X3C heme exporter protein FDZ86_RS08150 ENOG4105DA4 cytochrome c-type biogenesis protein FDZ86_RS08155 ENOG4107QX9 Thiol disulfide interChange protein FDZ86_RS08160 ENOG4105KWW Biogenesis protein FDZ86_RS08165 ENOG4105WH1 Two component transcriptional regulator luxr family FDZ86_RS08170 ENOG4108MGN ATP-binding component of a transport system FDZ86_RS08180 ENOG4105E68 Sulfatase FDZ86_RS08200 ENOG4105CFI type iii restriction protein res subunit FDZ86_RS08205 ENOG4105I08 Pseudouridine synthase FDZ86_RS08210 ENOG4105C2C drug resistance transporter, Bcr CflA FDZ86_RS08215 ENOG4105HG6 FDZ86_RS08220 ENOG4108JQ5 ABC transporter FDZ86_RS08225 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FDZ86_RS08230 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FDZ86_RS08235 ENOG4105E43 Extracellular solute-binding protein, family 5 FDZ86_RS08240 ENOG4105CXC rtn protein FDZ86_RS08245 ENOG4107TT5 NLP P60 protein FDZ86_RS08250 ENOG41076MN Phosphoesterase, PA-phosphatase related FDZ86_RS08255 ENOG4105CKI cobalamin synthesis protein FDZ86_RS08260 ENOG4105DEI Mannitol dehydrogenase FDZ86_RS08270 ENOG4105KRS Proteinase inhibitor FDZ86_RS08275 ENOG4105S8Q sugar efflux transporter FDZ86_RS08280 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FDZ86_RS08285 ENOG4105DE4 1-phosphofructokinase FDZ86_RS08290 ENOG4105DM4 PTS System FDZ86_RS08295 ENOG4105DD7 kinase (PfkB family FDZ86_RS08300 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) FDZ86_RS08305 ENOG4105D9N nucleoside FDZ86_RS08310 ENOG4108Y4K DNA-binding transcriptional activator FDZ86_RS08320 ENOG4105D9N nucleoside FDZ86_RS08325 ENOG4105DD7 kinase (PfkB family FDZ86_RS08330 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) FDZ86_RS08335 ENOG4105HMI Membrane FDZ86_RS08340 ENOG4105DUM transcriptional regulator, lysR family FDZ86_RS08345 ENOG4108IQI permease FDZ86_RS08350 ENOG4105D05 Receptor FDZ86_RS08355 ENOG4105C4W S-formylglutathione hydrolase FDZ86_RS08365 ENOG4105DHF Membrane FDZ86_RS08370 ENOG41060NJ transcriptional regulator FDZ86_RS08375 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FDZ86_RS08380 ENOG4105C2J ABC transporter FDZ86_RS08385 ENOG4108HWV )-transporter FDZ86_RS08390 ENOG4107SJI Dehydrogenase FDZ86_RS08395 ENOG4105BZ8 glutamate synthase FDZ86_RS08400 ENOG4105Y9N Membrane FDZ86_RS08405 ENOG4107GZ4 SanA protein FDZ86_RS08415 ENOG41067MG lrgb family FDZ86_RS08445 ENOG4108RXX maleylacetoacetate isomerase FDZ86_RS08450 ENOG4105MSY salicylate hydroxylase FDZ86_RS08455 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FDZ86_RS08470 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FDZ86_RS08475 ENOG4105KHU inner membrane protein YohD FDZ86_RS08480 ENOG41069YE inner membrane protein yohC FDZ86_RS08485 ENOG41061WM D-Alanyl-D-Alanine FDZ86_RS08490 ENOG4105CXG d-lactate dehydrogenase FDZ86_RS08495 ENOG4107QK4 glycoside hydrolase, family 3 domain protein FDZ86_RS08500 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system FDZ86_RS08505 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component FDZ86_RS08510 ENOG4108IJ8 ABC transporter FDZ86_RS08515 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component FDZ86_RS08525 ENOG4108XDN Transcriptional regulator FDZ86_RS08530 ENOG4107R08 Integrase FDZ86_RS08660 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi FDZ86_RS08665 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 FDZ86_RS08670 ENOG4105RWQ Protein of unknown function (DUF1364) FDZ86_RS08685 ENOG4105HRS Antitermination protein FDZ86_RS08725 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS08775 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FDZ86_RS08850 ENOG4108X9F tail fiber protein FDZ86_RS08870 ENOG4106FE3 DNA repair FDZ86_RS08875 ENOG4108HRK Histidine kinase FDZ86_RS08880 ENOG4108NEV two component transcriptional regulator, LytTR family FDZ86_RS08885 ENOG4108W15 Protein of unknown function (DUF1456) FDZ86_RS08890 ENOG4108YCW (LipO)protein FDZ86_RS08895 ENOG410903U zinc ion binding FDZ86_RS08900 ENOG4105DEG Vwa containing coxe family protein FDZ86_RS08905 ENOG4105RD5 FDZ86_RS08910 ENOG4105RD5 FDZ86_RS08915 ENOG4105KKX ATPase associated with various cellular activities aaa_5 FDZ86_RS08925 ENOG4108KDT Molybdate metabolism regulator FDZ86_RS08945 ENOG4105D1F ATP-binding protein FDZ86_RS08950 ENOG41067AK Protein of unknown function (DUF2574) FDZ86_RS08955 ENOG41063W2 Fimbrial protein FDZ86_RS08960 ENOG4108MQF Chaperone FDZ86_RS08965 ENOG4105CW0 outer membrane usher protein FDZ86_RS08970 ENOG410662B Type-1 fimbrial protein FDZ86_RS08975 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly FDZ86_RS09010 ENOG4105DWF phosphomethylpyrimidine kinase FDZ86_RS09015 ENOG4108UQ1 hydrolase, family 25 FDZ86_RS09020 ENOG4105FDP GntR family transcriptional regulator FDZ86_RS09025 ENOG4108TFM Kinase, PfkB family FDZ86_RS09030 ENOG4108KD5 ADP-ribosylation crystallin J1 FDZ86_RS09035 ENOG4105EAA nucleoside FDZ86_RS09040 ENOG4105EIE fructose-bisphosphate aldolase FDZ86_RS09055 ENOG41082GB PTS system galactitol-specific transporter subunit IIA FDZ86_RS09060 ENOG41090UW PTS System FDZ86_RS09065 ENOG4105DT3 PTS system, galactitol-specific IIc component FDZ86_RS09070 ENOG4107WTH Galactitol-1-phosphate dehydrogenase FDZ86_RS09085 ENOG41076Z6 Uncharacterized protein yegR FDZ86_RS09090 ENOG4105CFP Peptidase U32 FDZ86_RS09095 ENOG4105KWI UPF0339 protein FDZ86_RS09100 ENOG4105E3W Two component transcriptional regulator (Winged helix family FDZ86_RS09105 ENOG4105EB3 Histidine kinase FDZ86_RS09120 ENOG4105BZS acriflavin resistance protein FDZ86_RS09145 ENOG4108M24 von Willebrand factor, type A FDZ86_RS09150 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase FDZ86_RS09155 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding FDZ86_RS09160 ENOG4105R8A Heat shock protein FDZ86_RS09165 ENOG4105D03 DNA-3-methyladenine glycosylase II FDZ86_RS09175 ENOG4105DBI uridine monophosphokinase FDZ86_RS09185 ENOG4108GAE asmA family FDZ86_RS09200 ENOG4105EE5 Membrane protein terC FDZ86_RS09210 ENOG4105DAY polysaccharide export protein FDZ86_RS09215 ENOG4105KJF protein tyrosine phosphatase FDZ86_RS09220 ENOG4105D75 Capsular exopolysaccharide family FDZ86_RS09225 ENOG41090RK glycosyl transferase FDZ86_RS09230 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB FDZ86_RS09235 ENOG4107RXY Glycosyl transferase FDZ86_RS09240 ENOG4108NYJ Colanic acid FDZ86_RS09245 ENOG4105ECJ Glycosyl Transferase FDZ86_RS09250 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF FDZ86_RS09255 ENOG4105C0K Gdp-mannose 4,6-dehydratase FDZ86_RS09260 ENOG4105C30 Nad-dependent epimerase dehydratase FDZ86_RS09265 ENOG4105FGF GDP-mannose mannosyl hydrolase FDZ86_RS09270 ENOG4106CD9 glycosyl transferase group 1 FDZ86_RS09275 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FDZ86_RS09280 ENOG4107QKV phosphomannomutase FDZ86_RS09285 ENOG4105D3Q Sugar transferase FDZ86_RS09290 ENOG4105PSV Polysaccharide Biosynthesis Protein FDZ86_RS09295 ENOG4105C74 pyruvyl transferase FDZ86_RS09300 ENOG4107T8Q Glycosyl transferase (Group 1 FDZ86_RS09305 ENOG4105G1A colanic acid biosynthesis protein FDZ86_RS09310 ENOG4105DMT epimerase dehydratase FDZ86_RS09315 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FDZ86_RS09320 ENOG4105JEU Glycosyl transferase, family 2 FDZ86_RS09340 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FDZ86_RS09350 ENOG4105C0K Gdp-mannose 4,6-dehydratase FDZ86_RS09355 ENOG4105C30 Nad-dependent epimerase dehydratase FDZ86_RS09360 ENOG4105FGF GDP-mannose mannosyl hydrolase FDZ86_RS09365 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FDZ86_RS09370 ENOG4107QKV phosphomannomutase FDZ86_RS09375 ENOG4107WZ3 Transferase FDZ86_RS09380 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FDZ86_RS09385 ENOG4105C6Y Udp-glucose 6-dehydrogenase FDZ86_RS09410 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FDZ86_RS09415 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FDZ86_RS09425 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FDZ86_RS09440 ENOG4107SRH Nad-dependent epimerase dehydratase FDZ86_RS09445 ENOG4105EQ1 Transcriptional regulator FDZ86_RS09455 ENOG4105CUB amino acid FDZ86_RS09460 ENOG4105CUC YeeE YedE family protein FDZ86_RS09470 ENOG4105CJB Exodeoxyribonuclease I FDZ86_RS09475 ENOG4105DFP Integrase FDZ86_RS09605 ENOG4105CDU Replicative dna helicase FDZ86_RS09660 ENOG4108R1E Serine threonine protein phosphatase 1 FDZ86_RS09715 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS09720 ENOG4105KUS lysozyme FDZ86_RS09725 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FDZ86_RS09740 ENOG4106YSC FDZ86_RS09835 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FDZ86_RS09870 ENOG4108X9F tail fiber protein FDZ86_RS09880 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FDZ86_RS09890 ENOG4105DFP Integrase FDZ86_RS10020 ENOG4105CDU Replicative dna helicase FDZ86_RS10075 ENOG4108R1E Serine threonine protein phosphatase 1 FDZ86_RS10130 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS10135 ENOG4105KUS lysozyme FDZ86_RS10140 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FDZ86_RS10155 ENOG4106YSC FDZ86_RS10250 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FDZ86_RS10285 ENOG4108X9F tail fiber protein FDZ86_RS10295 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FDZ86_RS10305 ENOG4105DZ1 carboxypeptidase FDZ86_RS10315 ENOG4105DR8 Membrane FDZ86_RS10350 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FDZ86_RS10360 ENOG4108YGG dna repair protein FDZ86_RS10365 ENOG4105MFG Antirestriction protein FDZ86_RS10370 ENOG4106H6R UPF0380 protein FDZ86_RS10390 ENOG4108YIV FDZ86_RS10410 ENOG4105E5H Transposase FDZ86_RS10415 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS10425 ENOG4108YZT Adenosylcobinamide kinase FDZ86_RS10440 ENOG4108PXI ErfK YbiS YcfS YnhG FDZ86_RS10450 ENOG4106P55 Transcriptional regulator FDZ86_RS10455 ENOG4107R11 Transcriptional regulator FDZ86_RS10465 ENOG4105UQX Mate efflux family protein FDZ86_RS10475 ENOG4105CDY transcriptional regulatory protein FDZ86_RS10480 ENOG4105FYV Amp nucleosidase FDZ86_RS10485 ENOG4105CSH Transporter FDZ86_RS10495 ENOG4105TNG K13735 adhesin invasin FDZ86_RS10505 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) FDZ86_RS10530 ENOG4106G8A Qin prophage FDZ86_RS10615 ENOG4108MXB Protein of unknown function (DUF968) FDZ86_RS10620 ENOG4105KSK (crossover) junction endodeoxyribonuclease FDZ86_RS10665 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS10700 ENOG4106YSC FDZ86_RS10735 ENOG4105IM0 capsid protein FDZ86_RS10790 ENOG4108X9F tail fiber protein FDZ86_RS10810 ENOG4108VKM cytochrome b561 FDZ86_RS10815 ENOG4108MEK Metal-binding protein YodA FDZ86_RS10830 ENOG4105VT2 5-hydroxyisourate hydrolase FDZ86_RS10835 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FDZ86_RS10840 ENOG4107ZY3 Histidine kinase FDZ86_RS10860 ENOG4105EST Metal Dependent Phosphohydrolase FDZ86_RS10865 ENOG4105DVF Cytosine-specific methyltransferase FDZ86_RS10870 ENOG41090BB DNA mismatch endonuclease (vsr) FDZ86_RS10875 ENOG4105FDR Membrane FDZ86_RS10880 ENOG4105CKW Inner membrane protein yedI FDZ86_RS10885 ENOG4105VNZ cytoplasmic protein FDZ86_RS10890 ENOG4105BZU Histidine kinase FDZ86_RS10900 ENOG4105YX3 cellular response to acidity FDZ86_RS10910 ENOG4107TKS colanic acid capsular biosynthesis activation protein A FDZ86_RS10915 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FDZ86_RS10925 ENOG4105CN7 Flagellar biosynthetic protein FliP FDZ86_RS10930 ENOG4105K0P flagellar biosynthesis protein FDZ86_RS10935 ENOG4105DD5 Flagellar motor switch protein FDZ86_RS10940 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FDZ86_RS10945 ENOG4107ZI8 flagellar basal body-associated protein flil FDZ86_RS10950 ENOG4105WF4 Flagellar hook-length control protein FDZ86_RS10955 ENOG4105GSA Flagellar export protein flij FDZ86_RS10960 ENOG4108JIR Flagellum-specific ATP synthase FDZ86_RS10965 ENOG41090PJ Flagellar assembly protein FDZ86_RS10970 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FDZ86_RS10975 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) FDZ86_RS10980 ENOG4105VQ0 flagellar hook-basal body complex protein fliE FDZ86_RS10990 ENOG4108HF7 Gcn5-related n-acetyltransferase FDZ86_RS11000 ENOG4108HF7 Gcn5-related n-acetyltransferase FDZ86_RS11005 ENOG4108RAV Conserved protein FDZ86_RS11015 ENOG41066VF YeeE YedE family protein FDZ86_RS11020 ENOG4108W9D (LipO)protein FDZ86_RS11025 ENOG4105E5K Alpha-amylase FDZ86_RS11030 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) FDZ86_RS11035 ENOG4105MQ3 flagellar protein FliS FDZ86_RS11040 ENOG4105DTS flagellar hook-associated FDZ86_RS11045 ENOG4105I03 Flagellin FDZ86_RS11050 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FDZ86_RS11055 ENOG4108M9K flagella biosynthesis protein FliZ FDZ86_RS11060 ENOG4105EAB amino acid AbC transporter FDZ86_RS11070 ENOG4105E5Q amino acid AbC transporter FDZ86_RS11075 ENOG4105CDA abc transporter atp-binding protein FDZ86_RS11080 ENOG4105VJY transcriptional regulator FDZ86_RS11085 ENOG4105XVG cytoplasmic protein FDZ86_RS11095 ENOG4105WH1 Two component transcriptional regulator luxr family FDZ86_RS11135 ENOG4105F9F transposase FDZ86_RS11180 ENOG4105UZW Tail fiber assembly protein FDZ86_RS11280 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FDZ86_RS11285 ENOG4106RHG Yeca family FDZ86_RS11290 ENOG4105E0U tyrosine-specific transport protein FDZ86_RS11295 ENOG4105VVZ metal-binding protein FDZ86_RS11300 ENOG41090A1 ferritin FDZ86_RS11305 ENOG4105P23 (LipO)protein FDZ86_RS11315 ENOG4105N4N Protein of unknown function (DUF2766) FDZ86_RS11320 ENOG4108UEC Ferritin-like protein FDZ86_RS11325 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator FDZ86_RS11330 ENOG4105C2J ABC transporter FDZ86_RS11335 ENOG4105CNN ABC, transporter FDZ86_RS11340 ENOG4108K4C ec 3.1.3.12 FDZ86_RS11350 ENOG4108VA4 Universal stress protein FDZ86_RS11360 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region FDZ86_RS11365 ENOG4107RD7 Flagellar Motor Protein, MotA FDZ86_RS11370 ENOG4105ER2 Ompa motb domain protein FDZ86_RS11375 ENOG4105CBS Chea signal transduction histidine kinase FDZ86_RS11380 ENOG4108V3W Chemotaxis protein, CheW FDZ86_RS11385 ENOG4105C8Q Methyl-accepting chemotaxis FDZ86_RS11390 ENOG4105C8Q Methyl-accepting chemotaxis FDZ86_RS11395 ENOG4105BZU Histidine kinase FDZ86_RS11400 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FDZ86_RS11405 ENOG4108VYJ response regulator receiver protein FDZ86_RS11415 ENOG4105D00 flagellar biosynthetic protein flhB FDZ86_RS11420 ENOG4105D7B Flagellar biosynthesis protein flha FDZ86_RS11425 ENOG4105W13 flagellar protein FDZ86_RS11440 ENOG4106ZCM YecM protein FDZ86_RS11450 ENOG4105CUW cytochrome C-TYPE protein FDZ86_RS11455 ENOG4108J2R molybdopterin oxidoreductase FDZ86_RS11470 ENOG4105WJG Glutathione FDZ86_RS11475 ENOG41081XQ Conserved Protein FDZ86_RS11480 ENOG4105D3W isochorismatase FDZ86_RS11490 ENOG4108TIT dATP pyrophosphohydrolase FDZ86_RS11495 ENOG4105CDY transcriptional regulatory protein FDZ86_RS11505 ENOG4107S01 Repressor protein MetJ FDZ86_RS11525 ENOG4105FAV ABC, transporter FDZ86_RS11535 ENOG4105NXV High-affinity zinc uptake system protein FDZ86_RS11540 ENOG4105DR5 peptidase FDZ86_RS11545 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase FDZ86_RS11550 ENOG4105CA9 Pyruvate kinase FDZ86_RS11555 ENOG4106KNT transcriptional regulator FDZ86_RS11560 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FDZ86_RS11565 ENOG4105C01 Dihydroxy-acid dehydratase FDZ86_RS11570 ENOG4108UHU Aldolase FDZ86_RS11575 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR FDZ86_RS11580 ENOG4105X2V dna damage-inducible protein FDZ86_RS11590 ENOG4108Q2J Inner membrane protein YebE FDZ86_RS11595 ENOG4105CUG Oligopeptidase b FDZ86_RS11600 ENOG4105UMD exodeoxyribonuclease X FDZ86_RS11605 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FDZ86_RS11610 ENOG4105MPK DNA polymerase III subunit theta FDZ86_RS11615 ENOG4105FXM Copper resistance protein FDZ86_RS11620 ENOG4108PNC copper resistance FDZ86_RS11625 ENOG4105NKT exported protein FDZ86_RS11630 ENOG4108R1E Serine threonine protein phosphatase 1 FDZ86_RS11635 ENOG4105UVW uncharacterized protein yebW FDZ86_RS11640 ENOG4105WT8 Protein of unknown function (DUF1480) FDZ86_RS11650 ENOG4105DY2 Paraquat-inducible protein b FDZ86_RS11655 ENOG4105H2K paraquat-inducible protein a FDZ86_RS11660 ENOG4108ZGC gaf domain protein FDZ86_RS11670 ENOG4105CN1 protease FDZ86_RS11680 ENOG4105C0R drug resistance transporter emrb qaca subfamily FDZ86_RS11685 ENOG4105J4Q Transcriptional regulator FDZ86_RS11690 ENOG4105TIK FDZ86_RS11700 ENOG4105Q3Y exported protein FDZ86_RS11715 ENOG4105DHI Methyltransferase FDZ86_RS11730 ENOG4105F3R pts system mannose fructose sorbose family iid FDZ86_RS11735 ENOG4105ETZ PTS System FDZ86_RS11740 ENOG4105DAS pts system FDZ86_RS11745 ENOG4105EE5 Membrane protein terC FDZ86_RS11750 ENOG4107XTP (EAL) domain protein FDZ86_RS11755 ENOG4105EJQ L-serine dehydratase FDZ86_RS11765 ENOG4105CRQ synthase (Component I) FDZ86_RS11775 ENOG4105V2F Uncharacterized protein yoac FDZ86_RS11780 ENOG4105M4H endoribonuclease L-psp FDZ86_RS11785 ENOG4105DVT helicase FDZ86_RS11790 ENOG41072GX Peptidase M22 Glycoprotease FDZ86_RS11795 ENOG4105Y4Z Outer Membrane Lipoprotein FDZ86_RS11800 ENOG4105CEY Amp-dependent synthetase and ligase FDZ86_RS11805 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FDZ86_RS11810 ENOG4105E3J oxidoreductase FDZ86_RS11815 ENOG4105DVW rieske (2Fe-2S) FDZ86_RS11820 ENOG4105C94 Transporter FDZ86_RS11825 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FDZ86_RS11830 ENOG4105EJC lysr family transcriptional regulator FDZ86_RS11835 ENOG4108NIW Leucine export protein LeuE FDZ86_RS11840 ENOG4108YS1 cytoplasmic protein FDZ86_RS11845 ENOG4105YP6 Domain of unknown function (DUF1869) FDZ86_RS11850 ENOG4105Y3U Transglycosylase-associated protein FDZ86_RS11860 ENOG4106G4W FDZ86_RS11865 ENOG410620I Diguanylate cyclase FDZ86_RS11870 ENOG4105UCG Domain of unknown function (DUF333) FDZ86_RS11875 ENOG4105K78 MarR family Transcriptional regulator FDZ86_RS11880 ENOG4105DJ2 Major Facilitator Superfamily FDZ86_RS11885 ENOG4105R1U AraC Family Transcriptional Regulator FDZ86_RS11900 ENOG4108KXH Ybak prolyl-tRNA synthetase associated FDZ86_RS11905 ENOG4108KHP Diguanylate cyclase FDZ86_RS11910 ENOG4106KTS Inner membrane protein yeaI FDZ86_RS11920 ENOG4105CYN Serine protein kinase FDZ86_RS11925 ENOG4105GNX MltA-interacting MipA family protein FDZ86_RS11930 ENOG4105CV8 reductase FDZ86_RS11935 ENOG4105DSB aldose 1-epimerase FDZ86_RS11940 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FDZ86_RS11950 ENOG4105VUT cytoplasmic protein FDZ86_RS11955 ENOG4105CPQ Dehydrogenase FDZ86_RS11960 ENOG4107TE1 transport protein FDZ86_RS11965 ENOG4105CPQ Dehydrogenase FDZ86_RS11970 ENOG4105D2N Aldolase FDZ86_RS11975 ENOG4107UH8 sugar kinase FDZ86_RS11980 ENOG4105CPC Aldo Keto reductase FDZ86_RS11985 ENOG4105E98 transcriptional regulator DeoR family FDZ86_RS12000 ENOG4108RWI nicotinamidase FDZ86_RS12005 ENOG4105HDK L-asparaginase FDZ86_RS12015 ENOG4105D07 Signal peptide peptidase, SppA FDZ86_RS12020 ENOG41069NU Nitroreductase FDZ86_RS12025 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) FDZ86_RS12030 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FDZ86_RS12035 ENOG41065FB inner membrane protein ynji FDZ86_RS12040 ENOG4105D82 Glutamate dehydrogenase FDZ86_RS12045 ENOG4105MTM Protein of unknown function (DUF1496) FDZ86_RS12050 ENOG4105M6F mutator MutT protein FDZ86_RS12055 ENOG4108T9J Cdp-alcohol phosphatidyltransferase FDZ86_RS12060 ENOG4107RM6 sulfurtransferase FDZ86_RS12065 ENOG4108VGW abc transporter atp-binding protein FDZ86_RS12070 ENOG4105CXZ ABC transporter, permease FDZ86_RS12075 ENOG4105VNH ABC transporter solute-binding protein FDZ86_RS12080 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FDZ86_RS12085 ENOG4108N5C SNARE associated Golgi protein-related protein FDZ86_RS12090 ENOG4108KCW iron-sulfur cluster binding FDZ86_RS12095 ENOG4108RSN SNARE associated Golgi FDZ86_RS12100 ENOG4105CGK Exodeoxyribonuclease III FDZ86_RS12130 ENOG4108SPG Periplasmic Protein FDZ86_RS12140 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) FDZ86_RS12150 ENOG4105KKI DNA-binding transcriptional activator OsmE FDZ86_RS12155 ENOG4105VZJ PTS System FDZ86_RS12160 ENOG4105CK1 PTS System FDZ86_RS12165 ENOG4105VCP PTS System FDZ86_RS12170 ENOG4105EZV Transcriptional regulator FDZ86_RS12175 ENOG4105F8D glycoside hydrolase family 4 FDZ86_RS12185 ENOG4105CH6 catalase FDZ86_RS12200 ENOG4108ETY sodium dicarboxylate symporter FDZ86_RS12205 ENOG4107K5X Membrane-bound metal-dependent hydrolase FDZ86_RS12210 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 FDZ86_RS12215 ENOG4107PN8 YfeABCD locus regulator FDZ86_RS12225 ENOG4105P10 Uncharacterized protein ydiZ FDZ86_RS12230 ENOG4105DE4 1-phosphofructokinase FDZ86_RS12235 ENOG4108NE3 Salt-induced outer membrane protein FDZ86_RS12255 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FDZ86_RS12260 ENOG41082NX 50s ribosomal protein l35 FDZ86_RS12280 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FDZ86_RS12295 ENOG4108V06 Glutathione peroxidase FDZ86_RS12305 ENOG4108QBX (LipO)protein FDZ86_RS12310 ENOG4108TC0 Diguanylate phosphodiesterase FDZ86_RS12325 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FDZ86_RS12335 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FDZ86_RS12340 ENOG4105CEY Amp-dependent synthetase and ligase FDZ86_RS12345 ENOG41090P5 ferredoxin-like protein FDZ86_RS12350 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FDZ86_RS12355 ENOG4105C10 Electron transfer flavoprotein FDZ86_RS12360 ENOG4105CV7 Electron transfer flavoprotein FDZ86_RS12365 ENOG4105W4W Transcriptional regulator FDZ86_RS12370 ENOG4105C1G acyl-Coa dehydrogenase FDZ86_RS12375 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FDZ86_RS12390 ENOG4105EMV Major Facilitator FDZ86_RS12395 ENOG4105EMV Major Facilitator FDZ86_RS12400 ENOG4105SUA Ydil protein FDZ86_RS12410 ENOG4105IPI Membrane FDZ86_RS12415 ENOG4105CQB FAD linked oxidase domain protein FDZ86_RS12420 ENOG4105KA0 thioesterase Superfamily protein FDZ86_RS12425 ENOG410671Z uncharacterized protein ydiH FDZ86_RS12430 ENOG4108Z4V iron-sulfur cluster assembly FDZ86_RS12435 ENOG4105DIW FeS assembly protein SUFB FDZ86_RS12440 ENOG4105C3K feS assembly ATPase SufC FDZ86_RS12445 ENOG4105JRK feS assembly protein SufD FDZ86_RS12460 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FDZ86_RS12465 ENOG4105KMX major outer membrane lipoprotein FDZ86_RS12470 ENOG4105CA9 Pyruvate kinase FDZ86_RS12475 ENOG4105RFR Protein of unknown function (DUF2767) FDZ86_RS12480 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein FDZ86_RS12485 ENOG4105WE2 aldehyde ferredoxin oxidoreductase FDZ86_RS12490 ENOG4105JVW FDZ86_RS12495 ENOG4108393 oxidoreductase Fe-S subunit FDZ86_RS12500 ENOG4108NWD Cytochrome FDZ86_RS12505 ENOG4108Y7C Conserved Protein FDZ86_RS12510 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain FDZ86_RS12515 ENOG4105N0V mono-oxygenase ydhR FDZ86_RS12540 ENOG4108R6K riboflavin synthase, subunit alpha FDZ86_RS12545 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FDZ86_RS12550 ENOG4105CZQ inner membrane transport protein YdhC FDZ86_RS12555 ENOG4105F52 Transcriptional regulator FDZ86_RS12570 ENOG4105F27 Major Facilitator FDZ86_RS12575 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FDZ86_RS12580 ENOG4105K4H Nlp p60 protein FDZ86_RS12585 ENOG4105M2J Glutaredoxin FDZ86_RS12590 ENOG4107QRT dEAD DEAH box helicase FDZ86_RS12600 ENOG4108UYE Lactoylglutathione lyase FDZ86_RS12605 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDZ86_RS12610 ENOG4108WUH Transcriptional regulator, TetR family FDZ86_RS12615 ENOG4105XZD Fe-S protein FDZ86_RS12625 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FDZ86_RS12630 ENOG4105DSW Fusaric acid resistance protein FDZ86_RS12635 ENOG4105Y49 secretion protein, HlyD family FDZ86_RS12650 ENOG4108XTF Outer Membrane Lipoprotein FDZ86_RS12660 ENOG410642K Lysozyme inhibitor FDZ86_RS12675 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) FDZ86_RS12680 ENOG4108K3A Glutathione S-transferase FDZ86_RS12685 ENOG4105DUX Transporter FDZ86_RS12690 ENOG4105CSM endonuclease III FDZ86_RS12700 ENOG4108UQQ Electron transport complex FDZ86_RS12725 ENOG4105M9B inner membrane protein ydgK FDZ86_RS12730 ENOG4105QZ5 OriC-binding nucleoid-associated protein FDZ86_RS12735 ENOG4106C6R beta-lactam resistance protein FDZ86_RS12740 ENOG4105D9R oxidoreductase FDZ86_RS12750 ENOG4105C87 Aminotransferase class I and II FDZ86_RS12755 ENOG4105CI1 PTS System FDZ86_RS12760 ENOG4107P2S Transcriptional regulator FDZ86_RS12765 ENOG4107ZQV short-chain dehydrogenase reductase FDZ86_RS12770 ENOG4105XEA Tetr family transcriptional regulator FDZ86_RS12780 ENOG4105CT4 transporter FDZ86_RS12790 ENOG4106J39 exported protein FDZ86_RS12795 ENOG4105EIP mannose-6-phosphate isomerase FDZ86_RS12800 ENOG4107GFK fumarate FDZ86_RS12805 ENOG4105C9Q fumarate hydratase class II FDZ86_RS12810 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) FDZ86_RS12815 ENOG4105JJR Histidine kinase FDZ86_RS12820 ENOG4107EXC regulatoR FDZ86_RS12825 ENOG4105RA2 Membrane FDZ86_RS12835 ENOG4105D5Q Arginine ornithine antiporter FDZ86_RS12840 ENOG4105C5D exported protein FDZ86_RS12845 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FDZ86_RS12850 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FDZ86_RS12855 ENOG4105DSF transport protein FDZ86_RS12870 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap FDZ86_RS12885 ENOG4105D94 Major Facilitator Superfamily FDZ86_RS12890 ENOG4106NZI LysR family Transcriptional regulator FDZ86_RS12895 ENOG4105DAG ROK family FDZ86_RS12900 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FDZ86_RS12910 ENOG4108NEM leader-binding protein dmsD FDZ86_RS12915 ENOG4107KGK dmso reductase anchor subunit FDZ86_RS12920 ENOG4105QAX Iron-sulfur FDZ86_RS12925 ENOG4105C3J Cysteine desulfurase FDZ86_RS12930 ENOG4107QY8 reductase FDZ86_RS12935 ENOG4105KBG Protein of unknown function (DUF1161) FDZ86_RS12940 ENOG4105D69 UPF0257 lipoprotein ynfC FDZ86_RS12945 ENOG4108MK9 spermidine N(1)-acetyltransferase FDZ86_RS12975 ENOG4106G8A Qin prophage FDZ86_RS13030 ENOG4105JBR DNA replication protein FDZ86_RS13055 ENOG4105WI6 cell killing protein encoded within cryptic prophage FDZ86_RS13065 ENOG4108MXB Protein of unknown function (DUF968) FDZ86_RS13070 ENOG4105KSK (crossover) junction endodeoxyribonuclease FDZ86_RS13110 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS13145 ENOG4106YSC FDZ86_RS13250 ENOG4108X9F tail fiber protein FDZ86_RS13290 ENOG4108N8X transition metal ion binding FDZ86_RS13295 ENOG4108Z9Z response to DNA damage stimulus FDZ86_RS13315 ENOG4105DK0 Indole-3-glycerol phosphate synthase FDZ86_RS13320 ENOG4108EFP Anthranilate synthase component II FDZ86_RS13325 ENOG4105CRQ synthase (Component I) FDZ86_RS13335 ENOG4105DB7 PHP domain protein FDZ86_RS13340 ENOG4107RTD sua5 ycio yrdc ywlc family protein FDZ86_RS13345 ENOG4105EG3 transmembrane signal peptide protein FDZ86_RS13350 ENOG4105FE9 pseudouridine synthase FDZ86_RS13355 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FDZ86_RS13360 ENOG4105UBK short-chain dehydrogenase reductase FDZ86_RS13365 ENOG4105ERU peptidase FDZ86_RS13370 ENOG4105RKX Protein of unknown function (DUF2498) FDZ86_RS13375 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FDZ86_RS13380 ENOG4107R11 Transcriptional regulator FDZ86_RS13400 ENOG4107QM5 aconitate hydratase FDZ86_RS13410 ENOG4105EYK Phosphatidylglycerophosphatase B FDZ86_RS13415 ENOG4105Q4A inner membrane protein yciS FDZ86_RS13420 ENOG4105CFV Tetratricopeptide repeat protein FDZ86_RS13430 ENOG4108ZJT translation initiation factor, Sui1 FDZ86_RS13440 ENOG4105N2W Transcriptional regulator FDZ86_RS13450 ENOG4105BZU Histidine kinase FDZ86_RS13460 ENOG4105Q4T oxidoreductase FDZ86_RS13465 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FDZ86_RS13470 ENOG41067SE Tetr family transcriptional regulator FDZ86_RS13475 ENOG4105C1P efflux transporter, rnd family, mfp subunit FDZ86_RS13485 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDZ86_RS13490 ENOG4105C2C drug resistance transporter, Bcr CflA FDZ86_RS13495 ENOG4108JQ2 peptide transport system atp-binding protein FDZ86_RS13500 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein FDZ86_RS13505 ENOG4108EU3 peptide transport system, permease FDZ86_RS13510 ENOG4108I5W peptide transport system, permease protein FDZ86_RS13515 ENOG4108HIY periplasmic FDZ86_RS13520 ENOG4105N0E Protein of unknown function (DUF2543) FDZ86_RS13525 ENOG4105CUB amino acid FDZ86_RS13535 ENOG4105CFQ glutamine synthetase FDZ86_RS13540 ENOG4108Z86 Glutamine amidotransferase FDZ86_RS13545 ENOG4107VRI Transcriptional regulator FDZ86_RS13550 ENOG4105C26 Dehydrogenase FDZ86_RS13555 ENOG4105CJP fad dependent oxidoreductase FDZ86_RS13560 ENOG4108JPW Aminotransferase FDZ86_RS13565 ENOG4105E51 psp operon transcriptional activator FDZ86_RS13570 ENOG41087YS Phage shock protein A FDZ86_RS13575 ENOG4105YYT phage shock protein B FDZ86_RS13580 ENOG4105FM1 phage shock protein C FDZ86_RS13585 ENOG4105NNG Peripheral inner membrane phage-shock protein FDZ86_RS13590 ENOG4105K8Z Phage shock protein FDZ86_RS13605 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component FDZ86_RS13610 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FDZ86_RS13615 ENOG4107RRD Dehydrogenase FDZ86_RS13620 ENOG4107TYA transient receptor potential locus FDZ86_RS13625 ENOG4105CK5 oxidoreductase FDZ86_RS13630 ENOG4105C71 hydrolase family 65, central catalytic FDZ86_RS13635 ENOG4107URF beta-phospho-glucomutase FDZ86_RS13640 ENOG4108IJ9 (ABC) transporter FDZ86_RS13645 ENOG4107EFV Outer membrane protein G FDZ86_RS13650 ENOG4105FKQ transcriptional regulator FDZ86_RS13655 ENOG4105CM6 amino acid regulated cytosolic protein FDZ86_RS13665 ENOG4108JU8 Transcriptional regulator FDZ86_RS13670 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FDZ86_RS13675 ENOG4107S8C mandelate racemase muconate lactonizing FDZ86_RS13680 ENOG4105KXI murein peptide amidase A FDZ86_RS13695 ENOG4105ENX hydrolase FDZ86_RS13700 ENOG4105EQ2 LysR family Transcriptional regulator FDZ86_RS13705 ENOG4107QSI ABC, transporter FDZ86_RS13710 ENOG4105D64 Mechanosensitive ion channel FDZ86_RS13715 ENOG4105S5I Membrane FDZ86_RS13720 ENOG4105Q9Y Universal stress protein FDZ86_RS13725 ENOG4105DS0 Transcriptional regulator, Crp Fnr family FDZ86_RS13730 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FDZ86_RS13735 ENOG4105CFC Transporter FDZ86_RS13740 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B FDZ86_RS13745 ENOG4105CH2 amidohydrolase FDZ86_RS13750 ENOG4106KR7 LysR family Transcriptional regulator FDZ86_RS13755 ENOG4108DG9 Smr protein MutS2 FDZ86_RS13760 ENOG4105BZU Histidine kinase FDZ86_RS13775 ENOG4105C1J atp-dependent rna helicase FDZ86_RS13785 ENOG4107R08 Integrase FDZ86_RS13790 ENOG4107160 Rac prophage FDZ86_RS13795 ENOG41070YT Rac prophage FDZ86_RS13800 ENOG4106YAH restriction alleviation and modification enhancement FDZ86_RS13805 ENOG4108PNI recT protein FDZ86_RS13810 ENOG41076J9 exonuclease VIII FDZ86_RS13815 ENOG4107C82 Rac prophage FDZ86_RS13825 ENOG4106050 phage regulatory protein, rha family FDZ86_RS13850 ENOG4105ZTP Protein of unknown function (DUF1376) FDZ86_RS13855 ENOG4105JBR DNA replication protein FDZ86_RS13895 ENOG4105RWQ Protein of unknown function (DUF1364) FDZ86_RS13925 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS13980 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FDZ86_RS14055 ENOG4108X9F tail fiber protein FDZ86_RS14080 ENOG4108RW8 Universal stress protein F FDZ86_RS14090 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FDZ86_RS14095 ENOG4105IKK cytoplasmic protein FDZ86_RS14100 ENOG41090X5 Heat shock protein hslJ FDZ86_RS14105 ENOG4105C5I Dehydrogenase FDZ86_RS14110 ENOG4107H52 Dicarboxylate transport FDZ86_RS14115 ENOG410689M (LipO)protein FDZ86_RS14120 ENOG4105WXT Conserved Protein FDZ86_RS14130 ENOG4107EF2 surface-exposed virulence protein FDZ86_RS14135 ENOG4107S5I aldo keto reductase FDZ86_RS14145 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase FDZ86_RS14150 ENOG4108HPI phosphatidate Cytidylyltransferase FDZ86_RS14155 ENOG4105E8V Alpha Beta Hydrolase Fold protein FDZ86_RS14160 ENOG41077RS Phosphatase FDZ86_RS14165 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FDZ86_RS14170 ENOG4105CQ7 ATP-dependent helicase FDZ86_RS14195 ENOG4107DB1 DUF218 domain FDZ86_RS14200 ENOG4105C26 Dehydrogenase FDZ86_RS14205 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FDZ86_RS14210 ENOG4105CPW cytochrome b561 FDZ86_RS14215 ENOG4105UPP uncharacterized protein ydcA FDZ86_RS14220 ENOG4107NK6 Hok/gef family FDZ86_RS14225 ENOG4105C8Q Methyl-accepting chemotaxis FDZ86_RS14230 ENOG4105DDW LysR family Transcriptional regulator FDZ86_RS14235 ENOG4105E32 cytoplasmic protein FDZ86_RS14245 ENOG4105Z2P Protein of unknown function (DUF465) FDZ86_RS14255 ENOG4107WE3 acetyltransferase YdcK FDZ86_RS14260 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein FDZ86_RS14265 ENOG41088CC tellurite resistance protein tehB FDZ86_RS14270 ENOG4108KKZ (LipO)protein FDZ86_RS14275 ENOG4105DKK Benzoate FDZ86_RS14280 ENOG4108JCI Transcriptional regulator FDZ86_RS14285 ENOG4105CFP Peptidase U32 FDZ86_RS14290 ENOG4105RR0 Protein of unknown function (DUF2554) FDZ86_RS14300 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin FDZ86_RS14305 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDZ86_RS14310 ENOG4107TYH extracellular solute-binding protein family 1 FDZ86_RS14315 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS14320 ENOG4105D81 ABC transporter, permease FDZ86_RS14325 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component FDZ86_RS14340 ENOG410654E Membrane FDZ86_RS14345 ENOG4105R71 cytoplasmic protein FDZ86_RS14350 ENOG4108T9Y Inner membrane protein ydcZ FDZ86_RS14355 ENOG4108Z7F N-acetyltransferase FDZ86_RS14360 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FDZ86_RS14365 ENOG4108WYP Transcriptional regulator FDZ86_RS14370 ENOG4105CHB tonB-dependent Receptor FDZ86_RS14375 ENOG4108NS2 receptor FDZ86_RS14380 ENOG4105C85 amino acid FDZ86_RS14385 ENOG4108N27 Glutathione S-transferase FDZ86_RS14395 ENOG4105CS6 Rhs element vgr protein FDZ86_RS14400 ENOG4105CNA YD repeat protein FDZ86_RS14425 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS14430 ENOG4105E5H Transposase FDZ86_RS14445 ENOG4108MEJ flavin reductase domain protein FDZ86_RS14455 ENOG4105JAB phenazine biosynthesis protein, phzf family FDZ86_RS14460 ENOG4105D0D Nitrate reductase 2, gamma subunit FDZ86_RS14465 ENOG4108NZN Respiratory nitrate reductase 2 delta chain FDZ86_RS14470 ENOG4108IUE nitrate reductase beta subunit FDZ86_RS14475 ENOG4105CRU nitrate reductase, alpha subunit FDZ86_RS14480 ENOG4107QND Nitrite extrusion protein FDZ86_RS14490 ENOG4108UI3 Leucine Rich repeat FDZ86_RS14505 ENOG4105RPH Inner membrane protein YddG FDZ86_RS14515 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FDZ86_RS14520 ENOG4108MG3 formate dehydrogenase FDZ86_RS14525 ENOG41084S7 Plasmid maintenance system antidote protein FDZ86_RS14530 ENOG4105DQ4 alcohol dehydrogenase FDZ86_RS14540 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein FDZ86_RS14545 ENOG4105TPS biofilm-dependent modulation protein FDZ86_RS14550 ENOG4108Z9K Osmotically inducible protein FDZ86_RS14555 ENOG4107H6U ABC transporter FDZ86_RS14560 ENOG4105C3U ABC transporter FDZ86_RS14565 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FDZ86_RS14570 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FDZ86_RS14575 ENOG4105DEF Extracellular solute-binding protein, family 5 FDZ86_RS14580 ENOG4108UQS dipeptidase FDZ86_RS14590 ENOG4105BZU Histidine kinase FDZ86_RS14595 ENOG4105F32 YngK protein FDZ86_RS14600 ENOG4105E5D amino acid FDZ86_RS14605 ENOG4105CVK Glutamate decarboxylase FDZ86_RS14610 ENOG4107RAN Peptidase, M16 FDZ86_RS14615 ENOG4105PE1 Receptor FDZ86_RS14620 ENOG4105CQ0 ABC transporter FDZ86_RS14630 ENOG4105C4X radical SAM domain protein FDZ86_RS14635 ENOG4105ENH Sulfatase FDZ86_RS14640 ENOG4108NKV transcriptional regulator FDZ86_RS14650 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit FDZ86_RS14655 ENOG4106PIH fimbrial-like protein ydeQ FDZ86_RS14660 ENOG4106318 fimbrial-like protein YdeR FDZ86_RS14665 ENOG4108WDE Fimbrial protein FDZ86_RS14670 ENOG4105CW0 outer membrane usher protein FDZ86_RS14680 ENOG4108RQP Major type 1 subunit fimbrin FDZ86_RS14705 ENOG4107RYS Autoinducer-2 (AI-2) kinase FDZ86_RS14715 ENOG4105C2J ABC transporter FDZ86_RS14720 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane FDZ86_RS14725 ENOG4105F5R ABC transporter FDZ86_RS14735 ENOG41061GT Aldolase FDZ86_RS14740 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound FDZ86_RS14755 ENOG4105BZU Histidine kinase FDZ86_RS14760 ENOG4105M0C cytoplasmic protein FDZ86_RS14765 ENOG4105CSV Glutaminase FDZ86_RS14770 ENOG4105C26 Dehydrogenase FDZ86_RS14775 ENOG4105EGI Transcriptional regulator FDZ86_RS14790 ENOG4105F27 Major Facilitator FDZ86_RS14795 ENOG41082NP Multiple antibiotic resistance FDZ86_RS14800 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FDZ86_RS14805 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF FDZ86_RS14810 ENOG4106DNR multiple antibiotic resistance protein FDZ86_RS14815 ENOG4108594 Permease of the drug metabolite transporter FDZ86_RS14820 ENOG4105E5W Transporter FDZ86_RS14840 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria FDZ86_RS14845 ENOG4108YDI single-species biofilm formation on inanimate substrate FDZ86_RS14850 ENOG4108WTK competence damage-inducible protein FDZ86_RS14855 ENOG4105DGW oligopeptidase A FDZ86_RS14860 ENOG4105EMU Dehydrogenase FDZ86_RS14865 ENOG4107XBN GntR Family Transcriptional Regulator FDZ86_RS14870 ENOG41061EV selenium-binding protein YdfZ FDZ86_RS14875 ENOG4105DEI Mannitol dehydrogenase FDZ86_RS14910 ENOG4108X9F tail fiber protein FDZ86_RS14985 ENOG4105IM0 capsid protein FDZ86_RS14995 ENOG4105F7J membrane-bound serine protease FDZ86_RS15005 ENOG4107DE1 head-to-tail joining protein FDZ86_RS15010 ENOG4105UZW Tail fiber assembly protein FDZ86_RS15015 ENOG4105FKG DNA packaging protein FDZ86_RS15020 ENOG4106YSC FDZ86_RS15055 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS15100 ENOG4105KSK (crossover) junction endodeoxyribonuclease FDZ86_RS15105 ENOG4108MXB Protein of unknown function (DUF968) FDZ86_RS15115 ENOG4105H4F exported protein FDZ86_RS15120 ENOG4105WI6 cell killing protein encoded within cryptic prophage FDZ86_RS15200 ENOG4106G8A Qin prophage FDZ86_RS15205 ENOG41076J9 exonuclease VIII FDZ86_RS15215 ENOG4108I1J Integrase FDZ86_RS15265 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS15270 ENOG4105E5H Transposase FDZ86_RS15305 ENOG4108X9F tail fiber protein FDZ86_RS15415 ENOG4106YSC FDZ86_RS15450 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS15485 ENOG4105KSK (crossover) junction endodeoxyribonuclease FDZ86_RS15490 ENOG4108MXB Protein of unknown function (DUF968) FDZ86_RS15505 ENOG4105WI6 cell killing protein encoded within cryptic prophage FDZ86_RS15545 ENOG41087BU transcriptional repressor DicA FDZ86_RS15580 ENOG4106G8A Qin prophage FDZ86_RS15595 ENOG4108I1J Integrase FDZ86_RS15600 ENOG4105EIF outer membrane protein W FDZ86_RS15610 ENOG4108S3I UPF0259 membrane protein FDZ86_RS15620 ENOG4105NAU thioesterase Superfamily protein FDZ86_RS15625 ENOG410822N TonB family FDZ86_RS15630 ENOG4105K9H YciI-like protein FDZ86_RS15635 ENOG4107SVH Potassium channel protein FDZ86_RS15655 ENOG4108JQ7 (ABC) transporter FDZ86_RS15660 ENOG4105C3U ABC transporter FDZ86_RS15665 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FDZ86_RS15670 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FDZ86_RS15675 ENOG4108J59 Extracellular solute-binding protein, family 5 FDZ86_RS15680 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FDZ86_RS15685 ENOG4105C0A alcohol dehydrogenase FDZ86_RS15690 ENOG4107104 thymidine kinase FDZ86_RS15695 ENOG4108SAU DNA-binding protein H-ns FDZ86_RS15700 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FDZ86_RS15705 ENOG4105I93 response regulator FDZ86_RS15710 ENOG4105D78 K07001 NTE family protein FDZ86_RS15720 ENOG4105CIY formyltetrahydrofolate deformylase FDZ86_RS15750 ENOG41076YT nitrate reductase, gamma subunit FDZ86_RS15755 ENOG4105R3A Nitrate reductase FDZ86_RS15760 ENOG4108IUE nitrate reductase beta subunit FDZ86_RS15765 ENOG4105CRU nitrate reductase, alpha subunit FDZ86_RS15770 ENOG4105DQQ Major facilitator superfamily MFS_1 FDZ86_RS15775 ENOG4105BZU Histidine kinase FDZ86_RS15780 ENOG4105WH1 Two component transcriptional regulator luxr family FDZ86_RS15785 ENOG4105ID0 Putative invasin FDZ86_RS15790 ENOG41090EX DsrE family FDZ86_RS15795 ENOG4108NH8 Cation transport protein FDZ86_RS15800 ENOG4105WS7 Cation transport regulator FDZ86_RS15805 ENOG4105EWV Sodium calcium exchanger membrane region FDZ86_RS15825 ENOG41063JG Transcriptional regulator FDZ86_RS15830 ENOG4108YY7 Invasion gene expression up-regulator SirB FDZ86_RS15845 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) FDZ86_RS15855 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FDZ86_RS15860 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FDZ86_RS15865 ENOG4105CHH sulfate transporter FDZ86_RS15870 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria FDZ86_RS15880 ENOG4105C3G gtp-binding protein FDZ86_RS15885 ENOG4105I1J Autotransporter FDZ86_RS15890 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FDZ86_RS15910 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FDZ86_RS15925 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FDZ86_RS15935 ENOG4105ED1 spovr family FDZ86_RS15950 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) FDZ86_RS15955 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FDZ86_RS15960 ENOG4105KT5 UmuD protein FDZ86_RS15965 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells FDZ86_RS15975 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FDZ86_RS15990 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium FDZ86_RS15995 ENOG4105S66 prophage protein FDZ86_RS16005 ENOG4107QMS site-determining protein FDZ86_RS16025 ENOG4108NC2 Outer membrane protease FDZ86_RS16035 ENOG4105E5H Transposase FDZ86_RS16040 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS16055 ENOG4108WF3 methyltransferase FDZ86_RS16065 ENOG4108Z9Z response to DNA damage stimulus FDZ86_RS16070 ENOG4108N8X transition metal ion binding FDZ86_RS16075 ENOG4105WEF catalase FDZ86_RS16080 ENOG4105UZW Tail fiber assembly protein FDZ86_RS16085 ENOG4108X9F tail fiber protein FDZ86_RS16165 ENOG4105IM0 capsid protein FDZ86_RS16175 ENOG4105F7J membrane-bound serine protease FDZ86_RS16185 ENOG4107DE1 head-to-tail joining protein FDZ86_RS16190 ENOG4105UZW Tail fiber assembly protein FDZ86_RS16195 ENOG4105FKG DNA packaging protein FDZ86_RS16200 ENOG4106YSC FDZ86_RS16215 ENOG4105QYK bacteriophage lambda Bor protein homolog FDZ86_RS16245 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) FDZ86_RS16250 ENOG4105RWQ Protein of unknown function (DUF1364) FDZ86_RS16255 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 FDZ86_RS16260 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi FDZ86_RS16265 ENOG4107TII Recombinase FDZ86_RS16275 ENOG410814C multidrug resistance protein FDZ86_RS16300 ENOG4108I1J Integrase FDZ86_RS16305 ENOG4108HMX isocitrate dehydrogenase (NADP) FDZ86_RS16310 ENOG4108R99 pseudouridine synthase FDZ86_RS16320 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FDZ86_RS16330 ENOG4107QTF adenylosuccinate lyase FDZ86_RS16335 ENOG4105XJC Two component transcriptional regulator (Winged helix family FDZ86_RS16340 ENOG4105IFJ Histidine kinase FDZ86_RS16350 ENOG4105FKG DNA packaging protein FDZ86_RS16365 ENOG4105IM0 capsid protein FDZ86_RS16445 ENOG4105EZE Cupin 4 family protein FDZ86_RS16455 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS16615 ENOG4106YSC FDZ86_RS16660 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS16690 ENOG4105HGD Antitermination protein FDZ86_RS16695 ENOG4105KSK (crossover) junction endodeoxyribonuclease FDZ86_RS16700 ENOG4108MXB Protein of unknown function (DUF968) FDZ86_RS16710 ENOG4105WI6 cell killing protein encoded within cryptic prophage FDZ86_RS16775 ENOG4105W7J DNA binding FDZ86_RS16780 ENOG410649Z repressor FDZ86_RS16805 ENOG4108I1J Integrase FDZ86_RS16810 ENOG4105D38 putrescine abc transporter FDZ86_RS16815 ENOG4107RUE extracellular solute-binding protein family 1 FDZ86_RS16820 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FDZ86_RS16830 ENOG4105D60 lipoprotein releasing system transmembrane protein FDZ86_RS16835 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FDZ86_RS16840 ENOG4105D60 lipoprotein releasing system transmembrane protein FDZ86_RS16845 ENOG4105IQC Inner membrane protein YcfT FDZ86_RS16850 ENOG4108JA2 transcriptioN-repair coupling factor FDZ86_RS16855 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FDZ86_RS16860 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction FDZ86_RS16865 ENOG4108IND Tetr family transcriptional regulator FDZ86_RS16870 ENOG4107MBR 17 kDa surface antigen FDZ86_RS16875 ENOG4105CEP NADH dehydrogenase FDZ86_RS16890 ENOG4108RUM thiamine kinase FDZ86_RS16895 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) FDZ86_RS16900 ENOG41090DQ Lipoprotein FDZ86_RS16905 ENOG4105K59 histidine triad (HIT) protein FDZ86_RS16915 ENOG4105CNM Receptor FDZ86_RS16920 ENOG4105CI1 PTS System FDZ86_RS16925 ENOG4105F8V Hydrolase, tatD family FDZ86_RS16930 ENOG4107QRG dna polymerase iii FDZ86_RS16940 ENOG4105HHA aminodeoxychorismate lyase FDZ86_RS16945 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FDZ86_RS16950 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FDZ86_RS16955 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FDZ86_RS16960 ENOG4105CHR reductase FDZ86_RS16965 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FDZ86_RS16985 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FDZ86_RS16990 ENOG4108UHJ MAF-like protein FDZ86_RS16995 ENOG4105EI2 Pseudouridine synthase FDZ86_RS17000 ENOG4107QQB Ribonuclease E FDZ86_RS17005 ENOG4105DTJ flagellar hook-associated protein FDZ86_RS17010 ENOG4105E1Q flagellar hook-associated protein FDZ86_RS17015 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FDZ86_RS17030 ENOG4105CGA flagellar basal-body rod protein FlgG FDZ86_RS17035 ENOG4108KPB Flagellar basal-body rod protein FlgF FDZ86_RS17040 ENOG4105BZE flagellar hook protein, FlgE FDZ86_RS17045 ENOG4105W00 Flagellar hook capping protein FDZ86_RS17050 ENOG4108ZC9 flagellar basal-body rod protein flgc FDZ86_RS17055 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FDZ86_RS17060 ENOG4105CKS Flagella basal body P-ring formation protein flgA FDZ86_RS17065 ENOG4105M9M anti-sigma28 factor FlgM FDZ86_RS17070 ENOG4105QVD Flagella synthesis protein FlgN FDZ86_RS17075 ENOG4105CJR Integral membrane protein (MviN FDZ86_RS17080 ENOG4105EP9 oxidoreductase FDZ86_RS17090 ENOG4105D9U N-acetyltransferase FDZ86_RS17100 ENOG4105E9S glutaredoxin 2 FDZ86_RS17105 ENOG4105F3T (LipO)protein FDZ86_RS17115 ENOG4105MEA DNA damage-inducible protein i FDZ86_RS17120 ENOG4105PVA Biofilm formation regulatory protein BssS FDZ86_RS17130 ENOG4106974 biofilm formation FDZ86_RS17135 ENOG4105DS1 cytochrome b561 FDZ86_RS17140 ENOG4108YYC ycei family FDZ86_RS17150 ENOG4105D1S lipid A biosynthesis FDZ86_RS17160 ENOG4108W47 Acidic protein msyB FDZ86_RS17165 ENOG4105NAC (LipO)protein FDZ86_RS17170 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) FDZ86_RS17185 ENOG4107RZC phospholipase d FDZ86_RS17190 ENOG4108UVJ appr-1-p processing domain protein FDZ86_RS17205 ENOG41090QH cryptic curlin major subunit FDZ86_RS17210 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers FDZ86_RS17215 ENOG41086KC Transcriptional regulator FDZ86_RS17220 ENOG4108XDW curli assembly protein CsgE FDZ86_RS17225 ENOG4108WYR Curli production assembly transport component, CsgF FDZ86_RS17230 ENOG4105P8Q Curli production assembly transport component CsgG FDZ86_RS17235 ENOG4108UQ5 membrane protein YcdZ FDZ86_RS17240 ENOG4107XHZ cytoplasmic chaperone TorD family protein FDZ86_RS17280 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FDZ86_RS17290 ENOG4108YGG dna repair protein FDZ86_RS17295 ENOG4106549 Antirestriction protein FDZ86_RS17300 ENOG4106H6R UPF0380 protein FDZ86_RS17310 ENOG4108YIV FDZ86_RS17315 ENOG4108F5E vimentin FDZ86_RS17320 ENOG4105F4K antigen 43 FDZ86_RS17415 ENOG4105D05 Receptor FDZ86_RS17475 ENOG4105DAX Pfam:DUF2983 FDZ86_RS17510 ENOG4105E5H Transposase FDZ86_RS17515 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS17540 ENOG4105NRA 50s ribosomal protein l31 type b FDZ86_RS17585 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) FDZ86_RS17595 ENOG4105DIJ Phosphoethanolamine transferase FDZ86_RS17600 ENOG41080IJ Diacylglycerol kinase FDZ86_RS17640 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS17645 ENOG4105E5H Transposase FDZ86_RS17670 ENOG4108P8R FDZ86_RS17695 ENOG4105DFP Integrase FDZ86_RS17700 ENOG4108T85 Membrane FDZ86_RS17745 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FDZ86_RS17750 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) FDZ86_RS17760 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) FDZ86_RS17770 ENOG41081XD Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) FDZ86_RS17775 ENOG4105D5K Hemolysin activator protein FDZ86_RS17780 ENOG4105CKT filamentous hemagglutinin FDZ86_RS17790 ENOG4105X0I Fimbrial FDZ86_RS17795 ENOG4108AF8 Chaperone FDZ86_RS17800 ENOG4105CW0 outer membrane usher protein FDZ86_RS17810 ENOG4108MQF Chaperone FDZ86_RS17815 ENOG4105CHR reductase FDZ86_RS17820 ENOG4108TC1 Transcriptional regulator FDZ86_RS17830 ENOG4105CXC rtn protein FDZ86_RS17835 ENOG4105BZU Histidine kinase FDZ86_RS17840 ENOG4108TUY outer membrane protein PgaA FDZ86_RS17845 ENOG4107BJW polysaccharide deacetylase FDZ86_RS17850 ENOG4105CND Glycosyl transferase, family 2 FDZ86_RS17860 ENOG4105D5M phosphate starvation-inducible protein FDZ86_RS17865 ENOG4105DBE peroxidase FDZ86_RS17870 ENOG410650H (LipO)protein FDZ86_RS17885 ENOG4105CK7 Sodium proline symporter FDZ86_RS17895 ENOG4105C26 Dehydrogenase FDZ86_RS17900 ENOG4108R86 Transcriptional regulator FDZ86_RS17935 ENOG4105C2W permease FDZ86_RS17940 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 FDZ86_RS17950 ENOG4105XH3 FDZ86_RS17955 ENOG4105D6F Phosphatase FDZ86_RS17980 ENOG4108J2R molybdopterin oxidoreductase FDZ86_RS17985 ENOG4105CUW cytochrome C-TYPE protein FDZ86_RS17990 ENOG4106WF9 DNA-binding transcriptional regulator TorR FDZ86_RS17995 ENOG4108SV3 Tmao reductase system periplasmic protein tort FDZ86_RS18000 ENOG4105BZU Histidine kinase FDZ86_RS18005 ENOG4105HEE Binding Domain protein FDZ86_RS18010 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation FDZ86_RS18025 ENOG4105VEQ Cold shock protein FDZ86_RS18030 ENOG41060EU Cold shock-like protein FDZ86_RS18040 ENOG4108Y9B (LipO)protein FDZ86_RS18045 ENOG4108W78 Pfam:DUF1017 FDZ86_RS18050 ENOG4105E3R (LipO)protein FDZ86_RS18055 ENOG4105DAY polysaccharide export protein FDZ86_RS18060 ENOG4107ZF2 Phosphatase FDZ86_RS18065 ENOG4108F2G Chain length determinant protein FDZ86_RS18070 ENOG4105D6F Phosphatase FDZ86_RS18080 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FDZ86_RS18085 ENOG4105C4M (Ubiquinol oxidase) subunit I FDZ86_RS18090 ENOG4105MVP hydrogenase-1 operon protein HyaF FDZ86_RS18095 ENOG4108VXY Hydrogenase-1 operon protein HyaE FDZ86_RS18100 ENOG4108USZ hydrogenase FDZ86_RS18105 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit FDZ86_RS18110 ENOG4105DPX Hydrogenase, large subunit FDZ86_RS18115 ENOG4105E3S small subunit FDZ86_RS18135 ENOG4108X9F tail fiber protein FDZ86_RS18150 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FDZ86_RS18195 ENOG4105IM0 capsid protein FDZ86_RS18230 ENOG4105E5H Transposase FDZ86_RS18235 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS18250 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS18325 ENOG4105HRS Antitermination protein FDZ86_RS18330 ENOG4105KSK (crossover) junction endodeoxyribonuclease FDZ86_RS18335 ENOG4108MXB Protein of unknown function (DUF968) FDZ86_RS18370 ENOG4105JBR DNA replication protein FDZ86_RS18430 ENOG4106G8A Qin prophage FDZ86_RS18450 ENOG4108MN8 Membrane FDZ86_RS18455 ENOG4108Z0T Part of a sulfur-relay system (By similarity) FDZ86_RS18460 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FDZ86_RS18475 ENOG4105K4P CoA-binding domain protein FDZ86_RS18490 ENOG41088T4 Helicase IV FDZ86_RS18495 ENOG410901E Membrane FDZ86_RS18500 ENOG4105EM2 membrane FDZ86_RS18505 ENOG4108RZ1 DNA transformation protein FDZ86_RS18515 ENOG4105UYK outer membrane protein a FDZ86_RS18525 ENOG4105DAN ATP-dependent protease FDZ86_RS18535 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) FDZ86_RS18540 ENOG4108Q2G (LipO)protein FDZ86_RS18545 ENOG4105DY2 Paraquat-inducible protein b FDZ86_RS18550 ENOG4105F1S paraquat-inducible protein a FDZ86_RS18555 ENOG4105C5H ABC transporter FDZ86_RS18565 ENOG4105QVC MOSC domain-containing protein FDZ86_RS18570 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) FDZ86_RS18585 ENOG4105MX3 Fimbrial FDZ86_RS18590 ENOG4105Q7J Fimbrial FDZ86_RS18595 ENOG4108MDY Fimbrial FDZ86_RS18605 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae FDZ86_RS18610 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon FDZ86_RS18615 ENOG4108UZX fmn reductase FDZ86_RS18620 ENOG4105GVF (ABC) transporter FDZ86_RS18630 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FDZ86_RS18635 ENOG4105E2Y ABC, transporter FDZ86_RS18640 ENOG4105CD8 aminopeptidase N FDZ86_RS18650 ENOG4105C5S asparaginyl-tRNA synthetase FDZ86_RS18655 ENOG4105FCK Membrane FDZ86_RS18660 ENOG4105CGF Aromatic amino acid aminotransferase FDZ86_RS18665 ENOG4105C5X domain protein FDZ86_RS18670 ENOG4105EAQ (twin-arginine translocation) pathway signal FDZ86_RS18675 ENOG4105DIT ErfK YbiS YcfS YnhG family protein FDZ86_RS18685 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) FDZ86_RS18695 ENOG4106371 Methyltransferase FDZ86_RS18700 ENOG4107S90 membrAne FDZ86_RS18705 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups FDZ86_RS18720 ENOG4105T0Z Conserved Protein FDZ86_RS18730 ENOG4105BZ1 (ABC) transporter FDZ86_RS18735 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 FDZ86_RS18745 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FDZ86_RS18755 ENOG4108K0D peptidase, M48 FDZ86_RS18770 ENOG4107VMU Membrane FDZ86_RS18775 ENOG4105DDY UPF0142 protein ycaO FDZ86_RS18780 ENOG4105TMB Formate nitrite transporter FDZ86_RS18785 ENOG4105C6N Formate acetyltransferase FDZ86_RS18790 ENOG4105F1A Pyruvate formate-lyase FDZ86_RS18800 ENOG4105E5D amino acid FDZ86_RS18810 ENOG4105CHJ isochorismatase hydrolase FDZ86_RS18815 ENOG4107KGK dmso reductase anchor subunit FDZ86_RS18820 ENOG4105QAX Iron-sulfur FDZ86_RS18825 ENOG4107QY8 reductase FDZ86_RS18835 ENOG4105D1H recombination factor protein RarA FDZ86_RS18845 ENOG4105CNU cell division protein FtsK FDZ86_RS18855 ENOG4105C3M thioredoxin reductase FDZ86_RS18860 ENOG4108JJ9 ABC, transporter FDZ86_RS18865 ENOG4108JJ8 (ABC) transporter FDZ86_RS18875 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FDZ86_RS18885 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FDZ86_RS18895 ENOG4105VEQ Cold shock protein FDZ86_RS18900 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FDZ86_RS18905 ENOG4105DJY efflux transporter, rnd family, mfp subunit FDZ86_RS18910 ENOG4108MJ5 VirK protein FDZ86_RS18915 ENOG4105CPB ATP-dependent endonuclease of the OLD family FDZ86_RS18925 ENOG4105DWU Membrane FDZ86_RS18935 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FDZ86_RS18940 ENOG4105C7K acetolactate synthase FDZ86_RS18945 ENOG4105C5W Aldolase FDZ86_RS18950 ENOG4105CGD Nad-dependent epimerase dehydratase FDZ86_RS18955 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FDZ86_RS18960 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FDZ86_RS18975 ENOG41064MM (LipO)protein FDZ86_RS18980 ENOG4105E5Z arginine transporter ATP-binding subunit FDZ86_RS18985 ENOG4106PMH Extracellular solute-binding protein family 3 FDZ86_RS18990 ENOG4105GBT ABC transporter FDZ86_RS18995 ENOG4105DMR ABC, transporter FDZ86_RS19000 ENOG4106TNF Periplasmic binding protein FDZ86_RS19025 ENOG4105RBQ inner membrane protein ybjO FDZ86_RS19030 ENOG4105D38 putrescine abc transporter FDZ86_RS19035 ENOG4105F38 ABC transporter, permease FDZ86_RS19040 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS19045 ENOG4107RUE extracellular solute-binding protein family 1 FDZ86_RS19050 ENOG4108RMJ sensory transduction regulator FDZ86_RS19060 ENOG4108DBC nitroreductase FDZ86_RS19065 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress FDZ86_RS19070 ENOG41090BQ Glutaredoxin FDZ86_RS19075 ENOG4105GWF inner membrane protein YbjM FDZ86_RS19085 ENOG4108RFG Tetr family transcriptional regulator FDZ86_RS19090 ENOG4106UW1 Major Facilitator superfamily FDZ86_RS19095 ENOG4108HCJ Hydrolase FDZ86_RS19105 ENOG4107QF7 multi-drug FDZ86_RS19110 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FDZ86_RS19115 ENOG4107FB0 transcriptional regulator DeoR family FDZ86_RS19120 ENOG4105DZ1 carboxypeptidase FDZ86_RS19125 ENOG4108TGY Glutathione S-transferase FDZ86_RS19130 ENOG4105D8V Glucose sorbosone dehydrogenase FDZ86_RS19135 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway FDZ86_RS19155 ENOG41064RH membrane protein YliF FDZ86_RS19160 ENOG4105BZU Histidine kinase FDZ86_RS19170 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FDZ86_RS19175 ENOG4105DEF Extracellular solute-binding protein, family 5 FDZ86_RS19180 ENOG4108JQ6 ABC transporter FDZ86_RS19190 ENOG4105CVM Molybdenum cofactor synthesis domain protein FDZ86_RS19195 ENOG4105D06 uba thif-type nad fad binding protein FDZ86_RS19200 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FDZ86_RS19205 ENOG4105F1A Pyruvate formate-lyase FDZ86_RS19215 ENOG4108HCJ Hydrolase FDZ86_RS19220 ENOG41072TH Protein of unknown function (DUF1479) FDZ86_RS19225 ENOG4105C5H ABC transporter FDZ86_RS19230 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FDZ86_RS19235 ENOG4105F4P )-transporter FDZ86_RS19240 ENOG4105KST dependent repressor FDZ86_RS19250 ENOG4108I6E Sulfatase FDZ86_RS19255 ENOG4108T1M outer membrane protein x FDZ86_RS19265 ENOG4107AQZ Membrane FDZ86_RS19275 ENOG4107R0W ABC transporter FDZ86_RS19280 ENOG4105E5Q amino acid AbC transporter FDZ86_RS19285 ENOG4105CDA abc transporter atp-binding protein FDZ86_RS19290 ENOG4105D8X mechanosensitive ion channel FDZ86_RS19300 ENOG4105ZY9 UPF0379 protein ybiM FDZ86_RS19305 ENOG4108ESX Receptor FDZ86_RS19315 ENOG4105KSC Transcriptional regulator, TraR DksA family FDZ86_RS19320 ENOG4105VR4 UPF0379 protein ybiJ FDZ86_RS19325 ENOG4105DG4 malate L-lactate dehydrogenase FDZ86_RS19330 ENOG4108MTB glycosyl transferase family FDZ86_RS19335 ENOG4105DVT helicase FDZ86_RS19345 ENOG4105C1J atp-dependent rna helicase FDZ86_RS19350 ENOG4107MVR Transcriptional regulator FDZ86_RS19360 ENOG4105CJ1 ABC, transporter FDZ86_RS19365 ENOG4107QWP ABC-2 type transporter FDZ86_RS19370 ENOG4107QWP ABC-2 type transporter FDZ86_RS19375 ENOG4105I9U inner membrane protein ybhQ FDZ86_RS19380 ENOG4105X23 Endonuclease Exonuclease phosphatase FDZ86_RS19385 ENOG4105DZQ phospholipase D Transphosphatidylase FDZ86_RS19390 ENOG4107UXM Membrane FDZ86_RS19395 ENOG410733J conserved inner membrane protein FDZ86_RS19400 ENOG4105HFZ Membrane FDZ86_RS19405 ENOG4108ZAF Molybdopterin FDZ86_RS19410 ENOG4105M00 molybdopterin converting factor, subunit 1 FDZ86_RS19420 ENOG4108RIR Molybdenum cofactor biosynthesis protein FDZ86_RS19430 ENOG4105CHW UPF0052 protein FDZ86_RS19440 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FDZ86_RS19445 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FDZ86_RS19460 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FDZ86_RS19465 ENOG4108V1U phospholipid-binding protein FDZ86_RS19485 ENOG4105UZW Tail fiber assembly protein FDZ86_RS19510 ENOG4108X9F tail fiber protein FDZ86_RS19585 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FDZ86_RS19620 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FDZ86_RS19625 ENOG4105KUS lysozyme FDZ86_RS19630 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FDZ86_RS19670 ENOG4108R1E Serine threonine protein phosphatase 1 FDZ86_RS19735 ENOG4108I1J Integrase FDZ86_RS19740 ENOG4105NBR Pectinesterase FDZ86_RS19745 ENOG4107QM5 aconitate hydratase FDZ86_RS19750 ENOG4107QPK )-transporter FDZ86_RS19755 ENOG4105C7F AcnD-accessory protein PrpF FDZ86_RS19760 ENOG4105F04 LysR family Transcriptional regulator FDZ86_RS19770 ENOG4108K4B hydrolase FDZ86_RS19780 ENOG4105E0C molybdate abc transporter FDZ86_RS19785 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FDZ86_RS19795 ENOG4105F4R Transcriptional regulator mode FDZ86_RS19800 ENOG4105DKW ABC transporter FDZ86_RS19805 ENOG4105CMR udp-glucose 4-epimerase FDZ86_RS19810 ENOG4105F0Z galactose-1-phosphate uridylyltransferase FDZ86_RS19820 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FDZ86_RS19830 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FDZ86_RS19835 ENOG4105JND homeobox protein FDZ86_RS19840 ENOG4105PGM cation diffusion facilitator family transporter FDZ86_RS19845 ENOG4106Z1T Nicotinamide Mononucleotide Transporter FDZ86_RS19850 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FDZ86_RS19885 ENOG4105UFD tol-pal system protein YbgF FDZ86_RS19890 ENOG4105KCK Peptidoglycan-associated lipoprotein FDZ86_RS19900 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA FDZ86_RS19910 ENOG4105E02 MotA TolQ exbB proton channel FDZ86_RS19915 ENOG4107YD3 Thioesterase FDZ86_RS19920 ENOG4105KJB cyd operon protein YbgE FDZ86_RS19930 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FDZ86_RS19935 ENOG4105C4M (Ubiquinol oxidase) subunit I FDZ86_RS19950 ENOG4107WFU Glutamate mutase subunit sigma FDZ86_RS19960 ENOG4105DJI Methylaspartate mutase, E subunit FDZ86_RS19985 ENOG4107GFK fumarate FDZ86_RS19990 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FDZ86_RS19995 ENOG4105ETT transcriptional Regulator, LysR family FDZ86_RS20000 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FDZ86_RS20010 ENOG4105C7S Dehydrogenase FDZ86_RS20015 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FDZ86_RS20020 ENOG4105E33 succinate dehydrogenase FDZ86_RS20025 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FDZ86_RS20030 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FDZ86_RS20035 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FDZ86_RS20045 ENOG4105BZN citrate synthase FDZ86_RS20050 ENOG4106UBK fimbrial-like adhesin protein FDZ86_RS20055 ENOG4106PG1 outer membrane usher protein FDZ86_RS20060 ENOG4108TTM chaperone FDZ86_RS20065 ENOG4108MY7 Fimbrial FDZ86_RS20070 ENOG4108KK1 membrane protein AbrB duplication FDZ86_RS20075 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) FDZ86_RS20085 ENOG4107R7A Allophanate hydrolase subunit 2 FDZ86_RS20090 ENOG4105P4J Allophanate hydrolase, subunit 1 FDZ86_RS20095 ENOG4107QNR UPF0135 protein FDZ86_RS20100 ENOG4105DUX Transporter FDZ86_RS20105 ENOG4105CVP deoxyribo-dipyrimidine photolyase FDZ86_RS20110 ENOG4107SEY Conserved Protein FDZ86_RS20115 ENOG410600T transposase FDZ86_RS20125 ENOG4106R09 FDZ86_RS20130 ENOG4105CNA YD repeat protein FDZ86_RS20135 ENOG4105XIQ Protein of unknown function (DUF2517) FDZ86_RS20160 ENOG4105C08 Histidine kinase FDZ86_RS20165 ENOG4105EEX Two component transcriptional regulator (Winged helix family FDZ86_RS20175 ENOG4105CXN decarboxylase FDZ86_RS20180 ENOG4105D5Q Arginine ornithine antiporter FDZ86_RS20185 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 FDZ86_RS20190 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) FDZ86_RS20195 ENOG4105EV9 Alpha Beta Hydrolase FDZ86_RS20200 ENOG4105NNH LexA regulated protein FDZ86_RS20205 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) FDZ86_RS20215 ENOG41090R7 Ferric uptake FDZ86_RS20220 ENOG4105GX6 (LipO)protein FDZ86_RS20235 ENOG4105CI1 PTS System FDZ86_RS20245 ENOG4105CE4 GlcNAc 6-P deacetylase FDZ86_RS20250 ENOG4105E2R ROK family FDZ86_RS20255 ENOG4105D4U had-superfamily hydrolase, subfamily iia FDZ86_RS20260 ENOG4105CAQ asparagine synthetase FDZ86_RS20300 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FDZ86_RS20310 ENOG4105C9A Phoh family FDZ86_RS20320 ENOG4108JU5 Magnesium and cobalt efflux protein FDZ86_RS20325 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FDZ86_RS20330 ENOG4107RP9 extracellular solute-binding protein, family 3 FDZ86_RS20335 ENOG4105EAD ABC transporter FDZ86_RS20340 ENOG4105DRP amino acid AbC transporter FDZ86_RS20345 ENOG4105CDA abc transporter atp-binding protein FDZ86_RS20355 ENOG4105F7F Chaperone FDZ86_RS20365 ENOG41069CF Protein of unknown function (DUF1266) FDZ86_RS20370 ENOG4107JFD Sel1 repeat FDZ86_RS20375 ENOG4105QFC Hsc56 co-chaperone of HscC FDZ86_RS20380 ENOG41069CF Protein of unknown function (DUF1266) FDZ86_RS20390 ENOG4107PAI alpha helical protein FDZ86_RS20405 ENOG4105DJF DNA polymerase III, delta' subunit FDZ86_RS20415 ENOG4108TGR phosphatase FDZ86_RS20420 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) FDZ86_RS20430 ENOG4105CJN penicillin-binding protein FDZ86_RS20435 ENOG4105CNI cell division protein FtsW FDZ86_RS20440 ENOG4105K6T rare lipoprotein A FDZ86_RS20445 ENOG4105DZ1 carboxypeptidase FDZ86_RS20460 ENOG41064T2 transcriptional regulator, lysR family FDZ86_RS20470 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) FDZ86_RS20490 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) FDZ86_RS20495 ENOG4105CEE C4-dicarboxylate transporter FDZ86_RS20500 ENOG4106YYS transcriptional regulatory protein FDZ86_RS20505 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FDZ86_RS20510 ENOG4105DUA (citrate (pro-3S)-lyase ligase FDZ86_RS20520 ENOG4105CI0 Citrate lyase FDZ86_RS20525 ENOG4105CHY citrate lyase, alpha FDZ86_RS20535 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FDZ86_RS20540 ENOG4107QPK )-transporter FDZ86_RS20545 ENOG4105KTS ribonuclease FDZ86_RS20550 ENOG4105NXH GreA GreB family elongation factor FDZ86_RS20555 ENOG4105E2A Dehydrogenase FDZ86_RS20560 ENOG4108U51 Universal stress protein FDZ86_RS20565 ENOG4108JU3 Alkyl hydroperoxide reductase FDZ86_RS20570 ENOG4105D3R alkyl hydroperoxide reductase FDZ86_RS20575 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase FDZ86_RS20580 ENOG4105DQS Transcriptional regulator FDZ86_RS20585 ENOG4105BZV Phosphoadenosine phosphosulfate reductase FDZ86_RS20590 ENOG4105GTN ParB Domain Protein Nuclease FDZ86_RS20595 ENOG4105CHM Aminotransferase FDZ86_RS20600 ENOG4107SCQ Iron-containing alcohol dehydrogenase FDZ86_RS20605 ENOG4105VCD cytoplasmic protein FDZ86_RS20610 ENOG4105D22 carbon starvation protein FDZ86_RS20620 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FDZ86_RS20625 ENOG4105WQI isochorismatase FDZ86_RS20630 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FDZ86_RS20635 ENOG4105E4F Isochorismate synthase FDZ86_RS20640 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein FDZ86_RS20650 ENOG4105DQ5 transport system permease protein FDZ86_RS20655 ENOG4105TVJ transport system, permease FDZ86_RS20660 ENOG4105E0A ABC, transporter FDZ86_RS20665 ENOG4108QY5 Ferric enterobactin transport protein FDZ86_RS20670 ENOG4105C0W non-ribosomal peptide synthetase FDZ86_RS20675 ENOG41085A6 mbth domain-containing protein FDZ86_RS20680 ENOG4105E93 esterase FDZ86_RS20685 ENOG4107RNH Outer membrane receptor FepA FDZ86_RS20690 ENOG4108TSE Transferase FDZ86_RS20700 ENOG4107635 Hok Gef family protein FDZ86_RS20710 ENOG4105WQ6 Membrane FDZ86_RS20715 ENOG4105MSB protein, conserved in bacteria FDZ86_RS20720 ENOG4108RCM Nitroreductase FDZ86_RS20725 ENOG4105CUY Mechanosensitive ion channel FDZ86_RS20730 ENOG4105C85 amino acid FDZ86_RS20735 ENOG4108IJF Heavy metal efflux pump, CzcA FDZ86_RS20740 ENOG4105EP1 Efflux transporter rnd family, mfp subunit FDZ86_RS20745 ENOG410624V efflux system protein FDZ86_RS20750 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDZ86_RS20755 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FDZ86_RS20760 ENOG4105GR3 Histidine kinase FDZ86_RS20765 ENOG4105CS6 Rhs element vgr protein FDZ86_RS20775 ENOG4105CNA YD repeat protein FDZ86_RS20785 ENOG4105CNA YD repeat protein FDZ86_RS20795 ENOG410600T transposase FDZ86_RS20800 ENOG410802X bacteriophage n4 adsorption protein b FDZ86_RS20810 ENOG4105QUW FDZ86_RS20825 ENOG4108Q9V regulatoR FDZ86_RS20830 ENOG4108ZI2 Fimbrial protein FDZ86_RS20835 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) FDZ86_RS20840 ENOG4105CW0 outer membrane usher protein FDZ86_RS20845 ENOG4108AF8 Chaperone FDZ86_RS20850 ENOG4108WDE Fimbrial protein FDZ86_RS20860 ENOG4105WQ3 Rna-binding protein FDZ86_RS20865 ENOG4105S2T inner membrane protein YbcI FDZ86_RS20875 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FDZ86_RS20885 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FDZ86_RS20890 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FDZ86_RS20895 ENOG4105C5B carbamate kinase FDZ86_RS20900 ENOG4105G5A Protein of unknown function (DUF2877) FDZ86_RS20905 ENOG4107REC cytoplasmic protein FDZ86_RS20910 ENOG4107R1Q Membrane protein FdrA FDZ86_RS20915 ENOG4105DG4 malate L-lactate dehydrogenase FDZ86_RS20920 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FDZ86_RS20925 ENOG4105S0E allantoin catabolism protein FDZ86_RS20930 ENOG4105BZW Glycerate kinase FDZ86_RS20935 ENOG4105DTE Xanthine uracil vitamin C permease FDZ86_RS20945 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FDZ86_RS20950 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FDZ86_RS20955 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FDZ86_RS20960 ENOG41060W2 glyoxylate carboligase FDZ86_RS20965 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region FDZ86_RS20975 ENOG4107653 Transcriptional regulator FDZ86_RS20995 ENOG4105CNA YD repeat protein FDZ86_RS21000 ENOG4105CV6 ABC transporter, permease FDZ86_RS21005 ENOG4108I0Y (ABC) transporter FDZ86_RS21010 ENOG4108UJV acyl-CoA thioesterase i FDZ86_RS21015 ENOG4105E1F short-chain dehydrogenase reductase FDZ86_RS21020 ENOG4107QR8 Thioredoxin FDZ86_RS21025 ENOG4105C4B ABC transporter, permease FDZ86_RS21030 ENOG41083J0 (ABC) transporter FDZ86_RS21035 ENOG4107QX8 SPFH domain, Band 7 family protein FDZ86_RS21040 ENOG4105G5H Membrane FDZ86_RS21065 ENOG4107QZV Type I secretion membrane fusion protein FDZ86_RS21085 ENOG4107RY6 amino acid FDZ86_RS21090 ENOG4105CSV Glutaminase FDZ86_RS21095 ENOG4105C59 p-type ATPase FDZ86_RS21100 ENOG41081XE plasmid maintenance system antidote protein, xre family FDZ86_RS21105 ENOG4105MBR gumn family FDZ86_RS21110 ENOG4108Z66 YbaK ebsC protein FDZ86_RS21115 ENOG4105CGH 5'-nucleotidase FDZ86_RS21120 ENOG4105EU0 Major facilitator Superfamily FDZ86_RS21125 ENOG4105CKD glutathione-regulated potassium-efflux system protein FDZ86_RS21130 ENOG4107RE1 Inosine-guanosine kinase FDZ86_RS21165 ENOG4107QMP dna polymerase iii subunits gamma and tau FDZ86_RS21175 ENOG4105WD1 Membrane FDZ86_RS21180 ENOG4108URS primosomal replication protein n'' FDZ86_RS21185 ENOG4106428 Protein of unknown function (DUF2496) FDZ86_RS21190 ENOG4105EGS Mechanosensitive ion channel FDZ86_RS21195 ENOG4107XI7 Tetr family transcriptional regulator FDZ86_RS21200 ENOG4105C1P efflux transporter, rnd family, mfp subunit FDZ86_RS21205 ENOG4105BZS acriflavin resistance protein FDZ86_RS21210 ENOG4108UKR Biofilm formation regulator YbaJ FDZ86_RS21215 ENOG4105KF5 hemolysin expression-modulating protein FDZ86_RS21220 ENOG4108UW5 maltose o-acetyltransferase FDZ86_RS21225 ENOG4105GSJ Inner membrane protein ylaC FDZ86_RS21230 ENOG41066DG (EAL) domain protein FDZ86_RS21235 ENOG4105KCV RNA signal recognition particle 4.5S RNA FDZ86_RS21245 ENOG41080UX Methyltransferase FDZ86_RS21250 ENOG4108MNP Glycoprotein polysaccharide metabolism FDZ86_RS21255 ENOG4105C29 acyl-CoA thioesterase FDZ86_RS21260 ENOG4105BZU Histidine kinase FDZ86_RS21265 ENOG4108YZA Nitrogen regulatory protein pii FDZ86_RS21270 ENOG4105BZ1 (ABC) transporter FDZ86_RS21275 ENOG4105BZ1 (ABC) transporter FDZ86_RS21280 ENOG4108XM1 transcriptional regulator AsnC family FDZ86_RS21290 ENOG4108NFA extracellular solute-binding protein FDZ86_RS21300 ENOG4108TGP Thioesterase superfamily protein FDZ86_RS21305 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FDZ86_RS21310 ENOG4105EIN peptidylprolyl cis-trans isomerase FDZ86_RS21315 ENOG4105K70 DNA-binding protein FDZ86_RS21320 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FDZ86_RS21340 ENOG4105M85 Bola protein FDZ86_RS21345 ENOG4105IEY (LipO)protein FDZ86_RS21350 ENOG4105EYM Major Facilitator superfamily FDZ86_RS21355 ENOG4105E2S oxidase) subunit II FDZ86_RS21360 ENOG4105BZ9 Cytochrome C oxidase, subunit I FDZ86_RS21365 ENOG4105CCU oxidase (Subunit III) FDZ86_RS21370 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FDZ86_RS21380 ENOG4107RDB Major Facilitator FDZ86_RS21390 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FDZ86_RS21395 ENOG4107S0N DJ-1 family FDZ86_RS21410 ENOG4105CTB Polyprenyl synthetase FDZ86_RS21420 ENOG4105CPC Aldo Keto reductase FDZ86_RS21430 ENOG4108ZAI phosphatidylglycerophosphatase a FDZ86_RS21435 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FDZ86_RS21445 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FDZ86_RS21450 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FDZ86_RS21460 ENOG4108KIC (LipO)protein FDZ86_RS21465 ENOG4105DRB nucleoside-specific channel-forming protein FDZ86_RS21470 ENOG4105N1F Hnh endonuclease FDZ86_RS21480 ENOG4105X54 addiction module antidote protein FDZ86_RS21485 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FDZ86_RS21490 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FDZ86_RS21495 ENOG4105VIE preprotein translocase, subunit YajC FDZ86_RS21520 ENOG4107R28 alpha amylase, catalytic region FDZ86_RS21525 ENOG4105C85 amino acid FDZ86_RS21530 ENOG4105CWM branched-chain amino acid transport system II carrier protein FDZ86_RS21535 ENOG4105BZU Histidine kinase FDZ86_RS21540 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FDZ86_RS21545 ENOG4107RH8 nuclease SbcCD subunit D FDZ86_RS21550 ENOG4105EYH Exonuclease FDZ86_RS21555 ENOG4105F27 Major Facilitator FDZ86_RS21560 ENOG4105DKQ ROK family FDZ86_RS21585 ENOG4105HBA AroM protein FDZ86_RS21590 ENOG4105SS3 FDZ86_RS21605 ENOG4105II7 pyrroline-5-carboxylate reductase FDZ86_RS21610 ENOG4105BZU Histidine kinase FDZ86_RS21615 ENOG4105VIF phosphate starvation-inducible protein FDZ86_RS21620 ENOG4105G6Z alkaline phosphatase FDZ86_RS21635 ENOG4105CPF Cell wall formation (By similarity) FDZ86_RS21640 ENOG4105UNH Membrane FDZ86_RS21645 ENOG4105FR5 inner membrane protein YaiY FDZ86_RS21650 ENOG4107QS8 (LipO)protein FDZ86_RS21655 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 FDZ86_RS21660 ENOG4107R6D beta-lactam binding protein AmpH FDZ86_RS21665 ENOG4108PNB DNA-binding transcriptional regulator FDZ86_RS21675 ENOG4105D52 delta-aminolevulinic acid dehydratase FDZ86_RS21680 ENOG4105E2B Taurine dioxygenase FDZ86_RS21685 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FDZ86_RS21690 ENOG4108ETV ABC transporter FDZ86_RS21695 ENOG4106FTQ Taurine ABC transporter, periplasmic FDZ86_RS21700 ENOG4108KX4 response regulator FDZ86_RS21705 ENOG4105BZU Histidine kinase FDZ86_RS21710 ENOG4105CXY transporter FDZ86_RS21715 ENOG4105C4Y ABC transporter FDZ86_RS21720 ENOG4107RCV ABC transporter, permease FDZ86_RS21725 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS21740 ENOG4105C4W S-formylglutathione hydrolase FDZ86_RS21745 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FDZ86_RS21750 ENOG4108SC4 )-transporter FDZ86_RS21755 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) FDZ86_RS21770 ENOG4106HB6 Alpha beta hydrolase FDZ86_RS21785 ENOG4108K2P TRANSCRIPTIONal FDZ86_RS21790 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein FDZ86_RS21800 ENOG4105ETE Transcriptional regulator (LacI family FDZ86_RS21805 ENOG4105CNT hydrolase family 2 FDZ86_RS21810 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FDZ86_RS21815 ENOG4108UW5 maltose o-acetyltransferase FDZ86_RS21820 ENOG4105DJ2 Major Facilitator Superfamily FDZ86_RS21830 ENOG4107B2H carbonic anhydrase FDZ86_RS21835 ENOG4105DND Transcriptional regulator FDZ86_RS21840 ENOG4105DZC cytosine deaminase FDZ86_RS21845 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin FDZ86_RS21850 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FDZ86_RS21855 ENOG4105DXD 2-methylcitrate dehydratase FDZ86_RS21860 ENOG4105BZN citrate synthase FDZ86_RS21865 ENOG4105CR4 methylisocitrate lyase FDZ86_RS21870 ENOG4108JU7 Transcriptional regulator FDZ86_RS21875 ENOG4105TDT uncharacterized protein yahO FDZ86_RS21880 ENOG4105E82 cytochrome subunit of dehydrogenase FDZ86_RS21895 ENOG4105DQ4 alcohol dehydrogenase FDZ86_RS21900 ENOG4105CNN ABC, transporter FDZ86_RS21905 ENOG4105CNN ABC, transporter FDZ86_RS21910 ENOG4105C2J ABC transporter FDZ86_RS21915 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FDZ86_RS21925 ENOG4105DZC cytosine deaminase FDZ86_RS21930 ENOG4105C5B carbamate kinase FDZ86_RS21940 ENOG4107REC cytoplasmic protein FDZ86_RS21945 ENOG4107R1Q Membrane protein FdrA FDZ86_RS21950 ENOG4105N16 Protein of unknown function (DUF2877) FDZ86_RS21955 ENOG4107SNB ankyrin repeat protein YahD FDZ86_RS21970 ENOG4105BZU Histidine kinase FDZ86_RS21980 ENOG4105C94 Transporter FDZ86_RS22015 ENOG4105BZU Histidine kinase FDZ86_RS22040 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) FDZ86_RS22045 ENOG4107QR9 Iron-sulfur cluster binding protein FDZ86_RS22050 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FDZ86_RS22055 ENOG4108K01 transcriptional regulator FDZ86_RS22060 ENOG4107QN2 dihydrolipoyl dehydrogenase FDZ86_RS22065 ENOG41066GK UPF0379 protein ykgI FDZ86_RS22070 ENOG4108KBJ Inner membrane protein YkgB FDZ86_RS22075 ENOG4105CV8 reductase FDZ86_RS22100 ENOG410642W LysR family Transcriptional regulator FDZ86_RS22105 ENOG4105ENX hydrolase FDZ86_RS22110 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDZ86_RS22120 ENOG4105E5H Transposase FDZ86_RS22125 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS22155 ENOG4108GWT fimbrillin MatB FDZ86_RS22165 ENOG4108N3D putative enzyme FDZ86_RS22170 ENOG4106PYX Receptor FDZ86_RS22175 ENOG4108UD7 cell wall organization FDZ86_RS22180 ENOG4105PI0 Ferredoxin FDZ86_RS22185 ENOG4105R3P Inner membrane protein yagU FDZ86_RS22190 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit FDZ86_RS22195 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding FDZ86_RS22200 ENOG4105C7W Xanthine dehydrogenase FDZ86_RS22205 ENOG4107XAN XdhC and CoxI family FDZ86_RS22210 ENOG4107RTG Major Facilitator superfamily FDZ86_RS22215 ENOG4105ENX hydrolase FDZ86_RS22220 ENOG4105EQ2 LysR family Transcriptional regulator FDZ86_RS22230 ENOG4105EMU Dehydrogenase FDZ86_RS22315 ENOG4105DFP Integrase FDZ86_RS22335 ENOG4108C33 Resolvase FDZ86_RS22345 ENOG4108US3 tail fiber assembly FDZ86_RS22350 ENOG4105PTU response to oxidative stress FDZ86_RS22360 ENOG4105Y0G tail protein FDZ86_RS22365 ENOG4108T86 baseplate J family protein FDZ86_RS22385 ENOG4108NKR DNA circulation protein FDZ86_RS22405 ENOG4105TKZ Tail Sheath FDZ86_RS22455 ENOG4105CAR Terminase, large subunit FDZ86_RS22480 ENOG4105QYK bacteriophage lambda Bor protein homolog FDZ86_RS22515 ENOG4105HGD Antitermination protein FDZ86_RS22520 ENOG4108MXB Protein of unknown function (DUF968) FDZ86_RS22530 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) FDZ86_RS22560 ENOG4108S1U FDZ86_RS22580 ENOG4108R7K Metal Dependent Phosphohydrolase FDZ86_RS22585 ENOG41077V0 CPS-53 (KpLE1) prophage FDZ86_RS22595 ENOG4108KU3 Integrase FDZ86_RS22615 ENOG4105FCK Membrane FDZ86_RS22635 ENOG4105CIN aminoacyl-histidine dipeptidase FDZ86_RS22640 ENOG4108S2Y peptide Chain Release factor FDZ86_RS22650 ENOG4108HYG acetyltransferase FDZ86_RS22655 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome FDZ86_RS22660 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system FDZ86_RS22665 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FDZ86_RS22685 ENOG4108YS0 lipoprotein YafL FDZ86_RS22695 ENOG4105VXN addiction module toxin, RelE StbE family FDZ86_RS22700 ENOG4105F7V ErfK ybiS ycfS ynhG family protein FDZ86_RS22705 ENOG4105E7A Glutamine amidotransferase FDZ86_RS22715 ENOG4107QPN acyl-Coa dehydrogenase FDZ86_RS22720 ENOG4108WN0 inhibitor of vertebrate lysozyme FDZ86_RS22725 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FDZ86_RS22730 ENOG410600T transposase FDZ86_RS22745 ENOG4105CNA YD repeat protein FDZ86_RS22750 ENOG4105CS6 Rhs element vgr protein FDZ86_RS22755 ENOG4108WC9 type VI secretion system effector, hcp1 family FDZ86_RS22810 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FDZ86_RS22855 ENOG410600K aminopeptidase FDZ86_RS22865 ENOG4107RZZ dna polymerase iii epsilon subunit FDZ86_RS22875 ENOG4105D1A Methyltransferase FDZ86_RS22880 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FDZ86_RS22885 ENOG4105E9H Lytic Murein transglycosylase FDZ86_RS22890 ENOG4105F2W methyltransferase FDZ86_RS22900 ENOG4105HEI LysR family (Transcriptional regulator FDZ86_RS22905 ENOG4105CV8 reductase FDZ86_RS22940 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FDZ86_RS22945 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FDZ86_RS22950 ENOG4108UMI ABC transporter, permease FDZ86_RS22955 ENOG4105D01 (LipO)protein FDZ86_RS22960 ENOG4108R8X outer membrane lipoprotein FDZ86_RS22965 ENOG4108R96 Methyltransferase, YaeB family FDZ86_RS22975 ENOG4108UY0 (LipO)protein FDZ86_RS22980 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion FDZ86_RS22985 ENOG4108YZN class I peptide chain release factor FDZ86_RS22990 ENOG4108VWS Yaeq family FDZ86_RS23000 ENOG4105M1T rho-binding antiterminator FDZ86_RS23005 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FDZ86_RS23010 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FDZ86_RS23015 ENOG4105CXN decarboxylase FDZ86_RS23025 ENOG4105C0B DNA polymerase III (alpha subunit) FDZ86_RS23050 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FDZ86_RS23055 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) FDZ86_RS23065 ENOG4105DZP Membrane-associated zinc metalloprotease FDZ86_RS23070 ENOG4105KNE Phosphatidate cytidylyltransferase FDZ86_RS23075 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FDZ86_RS23080 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FDZ86_RS23105 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FDZ86_RS23125 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR FDZ86_RS23130 ENOG4105C0H protease FDZ86_RS23145 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FDZ86_RS23150 ENOG4105EN6 Membrane FDZ86_RS23175 ENOG4105S6R Iron-hydroxamate transporter permease subunit FDZ86_RS23180 ENOG4105J76 Periplasmic binding protein FDZ86_RS23185 ENOG4105E0A ABC, transporter FDZ86_RS23190 ENOG4105E0K tonB-dependent siderophore receptor FDZ86_RS23195 ENOG4105BZ4 penicillin-binding protein FDZ86_RS23200 ENOG4105CQ7 ATP-dependent helicase FDZ86_RS23205 ENOG4107XID 2'-5' rna ligase FDZ86_RS23220 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) FDZ86_RS23225 ENOG4105DJ0 Poly(A) Polymerase FDZ86_RS23230 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FDZ86_RS23240 ENOG4108VEV chaperone FDZ86_RS23245 ENOG4105CW0 outer membrane usher protein FDZ86_RS23250 ENOG4108XEY fimbrial-like adhesin protein FDZ86_RS23255 ENOG4105SYG Fimbrial protein FDZ86_RS23280 ENOG4108A32 Transposase FDZ86_RS23290 ENOG4107BJW polysaccharide deacetylase FDZ86_RS23295 ENOG4108YTN IIa component FDZ86_RS23300 ENOG4105E3A (ABC) transporter FDZ86_RS23305 ENOG4105DA5 (ABC) transporter FDZ86_RS23310 ENOG41077A9 carbonic anhydrase FDZ86_RS23315 ENOG4108UGV hypoxanthine phosphoribosyltransferase FDZ86_RS23320 ENOG4105DZG Dehydrogenase FDZ86_RS23325 ENOG4105E3B Multicopper oxidase FDZ86_RS23330 ENOG4108ZRK uncharacterized protein yacC FDZ86_RS23350 ENOG4107QIJ Aconitate hydratase 2 FDZ86_RS23355 ENOG4108NST exported protein FDZ86_RS23360 ENOG4107QN2 dihydrolipoyl dehydrogenase FDZ86_RS23365 ENOG4107QSN dihydrolipoamide acetyltransferase FDZ86_RS23370 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FDZ86_RS23375 ENOG41073TP transcriptional regulator FDZ86_RS23380 ENOG4105C85 amino acid FDZ86_RS23385 ENOG4106A72 regulatory protein AmpE FDZ86_RS23390 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FDZ86_RS23395 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FDZ86_RS23400 ENOG4108ZUW Major pilin subunit FDZ86_RS23405 ENOG4107QHF type ii secretion system protein e FDZ86_RS23410 ENOG4105D7Q type ii secretion system FDZ86_RS23420 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FDZ86_RS23435 ENOG4105M6F mutator MutT protein FDZ86_RS23455 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FDZ86_RS23460 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FDZ86_RS23465 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FDZ86_RS23470 ENOG4105CPF Cell wall formation (By similarity) FDZ86_RS23485 ENOG4105CNI cell division protein FtsW FDZ86_RS23490 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FDZ86_RS23500 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FDZ86_RS23505 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FDZ86_RS23510 ENOG4105CJN penicillin-binding protein FDZ86_RS23515 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FDZ86_RS23530 ENOG4107B7Y DNA-binding transcriptional regulator FruR FDZ86_RS23540 ENOG4108ZP8 Acetolactate synthase small subunit FDZ86_RS23545 ENOG4105C7K acetolactate synthase FDZ86_RS23550 ENOG41064T2 transcriptional regulator, lysR family FDZ86_RS23565 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FDZ86_RS23585 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FDZ86_RS23595 ENOG4105DP9 ABC transporter FDZ86_RS23600 ENOG4106SMU thiamine transporter membrane protein FDZ86_RS23605 ENOG4107T0D ABC, transporter FDZ86_RS23610 ENOG4108KF1 Membrane FDZ86_RS23615 ENOG41063TF transcriptional regulator (AraC FDZ86_RS23630 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FDZ86_RS23635 ENOG4105CQ2 DNA polymerase FDZ86_RS23640 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FDZ86_RS23645 ENOG4105D3G Pseudouridine synthase FDZ86_RS23660 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) FDZ86_RS23665 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FDZ86_RS23670 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FDZ86_RS23705 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FDZ86_RS23720 ENOG4105C54 Major Facilitator superfamily FDZ86_RS23725 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein FDZ86_RS23730 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FDZ86_RS23765 ENOG4106YT9 Enoyl-CoA hydratase FDZ86_RS23775 ENOG4108XNW Transcriptional activatory protein CaiF FDZ86_RS23780 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FDZ86_RS23785 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FDZ86_RS23805 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FDZ86_RS23820 ENOG4105DTN riboflavin biosynthesis protein ribF FDZ86_RS23825 ENOG410647N response to DNA damage stimulus FDZ86_RS23845 ENOG4108MQF Chaperone FDZ86_RS23850 ENOG4105CW0 outer membrane usher protein FDZ86_RS23860 ENOG41063Z6 transcriptional regulator, lysR family FDZ86_RS23870 ENOG4105WI6 cell killing protein encoded within cryptic prophage FDZ86_RS23890 ENOG4108QUJ UPF0174 protein YaaW FDZ86_RS23895 ENOG4106HK8 GPR1 FUN34 yaaH family protein FDZ86_RS23900 ENOG4108RIR Molybdenum cofactor biosynthesis protein FDZ86_RS23905 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FDZ86_RS23910 ENOG4105BZG amino acid carrier protein FDZ86_RS23920 ENOG41062C6 Protein of unknown function (DUF2502) FDZ86_RS23925 ENOG4105D98 threonine synthase FDZ86_RS23935 ENOG4105CFH Aspartokinase FDZ86_RS23945 ENOG4106FVC RNA methyltransferase FDZ86_RS23950 ENOG410759A FDZ86_RS23955 ENOG41065U4 response regulator FDZ86_RS23960 ENOG4105CT7 inner membrane cred family protein FDZ86_RS23965 ENOG4105EB3 Histidine kinase FDZ86_RS23970 ENOG4105E3W Two component transcriptional regulator (Winged helix family FDZ86_RS23975 ENOG4108RH0 Crea protein FDZ86_RS23980 ENOG4105UEI Transcriptional Regulator AraC Family FDZ86_RS23990 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FDZ86_RS24000 ENOG4107SC1 transglycosylase FDZ86_RS24005 ENOG4105C5H ABC transporter FDZ86_RS24015 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase FDZ86_RS24020 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FDZ86_RS24025 ENOG4105EAC phosphoserine phosphatase FDZ86_RS24035 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) FDZ86_RS24070 ENOG41076CZ activating enzyme FDZ86_RS24075 ENOG4105EYA deoxyribonuclease FDZ86_RS24080 ENOG4108NRW Phospholipase, patatin family FDZ86_RS24090 ENOG4105K3G Periplasmic Protein FDZ86_RS24100 ENOG4105PAD Hydrolase FDZ86_RS24105 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FDZ86_RS24110 ENOG4108WPU DNA polymerase III subunit psi FDZ86_RS24125 ENOG4105YBH Protein of unknown function (DUF1435) FDZ86_RS24130 ENOG4108819 ferric iron reductase FDZ86_RS24135 ENOG4108T94 DNA-binding transcriptional activator BglJ FDZ86_RS24140 ENOG4108N8T regulatoR FDZ86_RS24145 ENOG4105DWK Membrane FDZ86_RS24160 ENOG4106CVF DNA replication protein FDZ86_RS24165 ENOG4105RI1 glycoprotein receptor FDZ86_RS24175 ENOG4105CPQ Dehydrogenase FDZ86_RS24180 ENOG410617M Transcriptional regulator FDZ86_RS24185 ENOG4108I5G Major Facilitator superfamily FDZ86_RS24190 ENOG4105C8Q Methyl-accepting chemotaxis FDZ86_RS24200 ENOG4105D22 carbon starvation protein FDZ86_RS24205 ENOG4105VCD cytoplasmic protein FDZ86_RS24210 ENOG4105CKI cobalamin synthesis protein FDZ86_RS24225 ENOG4108F3G Type I restriction-modification system, R subunit FDZ86_RS24235 ENOG4107QTH restriction modification system DNA specificity domain FDZ86_RS24255 ENOG4106DIZ Domain of unknown function (DUF1127) FDZ86_RS24260 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDZ86_RS24270 ENOG41083G8 Multidrug resistance protein MdtM FDZ86_RS24275 ENOG4106BRA Membrane FDZ86_RS24280 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase FDZ86_RS24285 ENOG4105CIZ coA-substrate-specific enzyme activase FDZ86_RS24300 ENOG4108ZK4 sdia-regulated domain-containing protein FDZ86_RS24305 ENOG4105CBP Major Facilitator FDZ86_RS24320 ENOG41074DU domain protein FDZ86_RS24325 ENOG4108P2H Inner membrane protein YjiG FDZ86_RS24330 ENOG4105DYB Isoaspartyl dipeptidase FDZ86_RS24355 ENOG4105C6F GntR Family Transcriptional Regulator FDZ86_RS24360 ENOG4105DEI Mannitol dehydrogenase FDZ86_RS24370 ENOG4107EFN gluconate transport system permease 3 FDZ86_RS24375 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin FDZ86_RS24380 ENOG4108T65 Fimbrial FDZ86_RS24385 ENOG4108SQA Fimbrial FDZ86_RS24390 ENOG4105CW0 outer membrane usher protein FDZ86_RS24395 ENOG4108NAE Fimbrial chaperone protein FDZ86_RS24400 ENOG4108S54 Fimbrial protein FDZ86_RS24405 ENOG4108RQP Major type 1 subunit fimbrin FDZ86_RS24410 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off FDZ86_RS24415 ENOG4108W9T type 1 fimbriae regulatory protein FDZ86_RS24420 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria FDZ86_RS24425 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) FDZ86_RS24440 ENOG4105C4R Atp-dependent dna helicase FDZ86_RS24445 ENOG4108I5C dEAD DEAH box helicase FDZ86_RS24455 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FDZ86_RS24465 ENOG4108I5C dEAD DEAH box helicase FDZ86_RS24585 ENOG4105DQ4 alcohol dehydrogenase FDZ86_RS24590 ENOG4105D7A ATP-binding protein FDZ86_RS24595 ENOG4108K5H permease YjgP YjgQ family protein FDZ86_RS24600 ENOG4108M8S permease YjgP YjgQ family protein FDZ86_RS24610 ENOG4105MYG DNA polymerase iii, chi subunit FDZ86_RS24620 ENOG4108M3P Membrane FDZ86_RS24625 ENOG4108MJ3 acetyltransferase FDZ86_RS24630 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) FDZ86_RS24635 ENOG4105DBV ornithine carbamoyltransferase FDZ86_RS24645 ENOG4105XEP YhcH YjgK YiaL family protein FDZ86_RS24650 ENOG4108XFH Transcriptional regulator FDZ86_RS24655 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FDZ86_RS24660 ENOG4108UQ8 endoribonuclease L-psp FDZ86_RS24665 ENOG4107C93 pyrBI operon leader peptide FDZ86_RS24680 ENOG4105KME endoribonuclease L-psp FDZ86_RS24685 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FDZ86_RS24695 ENOG4105D4X repressor FDZ86_RS24700 ENOG4105C5Y PTS System FDZ86_RS24705 ENOG4105CG3 alpha amylase, catalytic region FDZ86_RS24710 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FDZ86_RS24715 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) FDZ86_RS24725 ENOG4105CMS peptidase U62, modulator of DNA gyrase FDZ86_RS24735 ENOG4105DFU Cell wall formation (By similarity) FDZ86_RS24745 ENOG41062B0 ABC transporter, permease FDZ86_RS24750 ENOG4107R9N ABC transporter FDZ86_RS24755 ENOG4105C2J ABC transporter FDZ86_RS24760 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator FDZ86_RS24765 ENOG4105F0N pyrophosphate phospho-hydrolase FDZ86_RS24770 ENOG4105MZG transcriptional modulator of maze toxin, mazf FDZ86_RS24775 ENOG41087RY SpoVT_AbrB FDZ86_RS24780 ENOG4108ZHD aig2 family FDZ86_RS24785 ENOG4105MA0 exported protein FDZ86_RS24790 ENOG4105CFU surface antigen FDZ86_RS24800 ENOG4105C37 (CBS) domain FDZ86_RS24805 ENOG41061GZ Protein of unknown function (DUF1107) FDZ86_RS24810 ENOG4108UUE Transcriptional regulator FDZ86_RS24820 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FDZ86_RS24825 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic FDZ86_RS24830 ENOG4105KVH Transcriptional regulator FDZ86_RS24835 ENOG4105ECR NmrA family FDZ86_RS24840 ENOG4105DXC membrane FDZ86_RS24850 ENOG4105C85 amino acid FDZ86_RS24855 ENOG4108V1T peptidylprolyl cis-trans isomerase FDZ86_RS24860 ENOG4105FHY Opacity-associated protein A FDZ86_RS24870 ENOG4105D7V transposase FDZ86_RS24875 ENOG4108RS6 transposase FDZ86_RS24895 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FDZ86_RS24910 ENOG4105KIT UPF0379 protein yjfY FDZ86_RS24930 ENOG4106ETB IIa component FDZ86_RS24935 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport FDZ86_RS24940 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FDZ86_RS24955 ENOG4108MXZ Esterase FDZ86_RS24960 ENOG4105WSB biofilm stress and motility protein A FDZ86_RS24965 ENOG4105S17 UPF0379 protein yjfN FDZ86_RS24970 ENOG4105CSU acyl-Coa dehydrogenase FDZ86_RS24975 ENOG4106032 Glutathionylspermidine synthase FDZ86_RS24980 ENOG4108KXT Conserved Protein FDZ86_RS24985 ENOG4105Z6B inner membrane protein yjfl FDZ86_RS24990 ENOG4107VNS Protein of unknown function (DUF2491) FDZ86_RS24995 ENOG4108P9J Phage shock protein A FDZ86_RS25000 ENOG4105FUX Conserved Protein FDZ86_RS25005 ENOG4105C2N RNA methyltransferase TrmH family group 3 FDZ86_RS25010 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FDZ86_RS25030 ENOG4105EPW hflc protein FDZ86_RS25035 ENOG4107QJR hflk protein FDZ86_RS25040 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FDZ86_RS25060 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FDZ86_RS25065 ENOG4105K8N protein family UPF0079, ATPase FDZ86_RS25070 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FDZ86_RS25100 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) FDZ86_RS25115 ENOG4105EGS Mechanosensitive ion channel FDZ86_RS25120 ENOG4107SC7 Inner membrane transporter yjeM FDZ86_RS25130 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FDZ86_RS25135 ENOG4105E33 succinate dehydrogenase FDZ86_RS25150 ENOG41066YJ Beta-lactamase FDZ86_RS25155 ENOG4105QNF Outer membrane lipoprotein FDZ86_RS25160 ENOG4105KPY Small multidrug resistance protein FDZ86_RS25165 ENOG4106BSU Entericidin B FDZ86_RS25170 ENOG4107PEH Entericidin EcnA/B family FDZ86_RS25180 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FDZ86_RS25185 ENOG4105MTB Uncharacterized protein YjeJ FDZ86_RS25190 ENOG4108ZVF (LipO)protein FDZ86_RS25205 ENOG4105DVH amino acid FDZ86_RS25210 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 FDZ86_RS25215 ENOG4108IJ0 Aspartate ammonia-lyase FDZ86_RS25220 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FDZ86_RS25230 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FDZ86_RS25235 ENOG4108SIC Transcriptional regulator FDZ86_RS25245 ENOG4108M3R transcriptional activator CadC FDZ86_RS25250 ENOG4105D5Q Arginine ornithine antiporter FDZ86_RS25255 ENOG4105CXN decarboxylase FDZ86_RS25260 ENOG4105DUX Transporter FDZ86_RS25265 ENOG4105CRK lysyL-tRNA synthetase FDZ86_RS25280 ENOG410830R acetyltransferase FDZ86_RS25285 ENOG4105VR1 Pfam:DUF1271 FDZ86_RS25290 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FDZ86_RS25295 ENOG4108MRH transcriptional regulatory protein FDZ86_RS25300 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FDZ86_RS25305 ENOG4107GFK fumarate FDZ86_RS25310 ENOG4108R5S membrane FDZ86_RS25315 ENOG4105CT4 transporter FDZ86_RS25320 ENOG4105F8D glycoside hydrolase family 4 FDZ86_RS25325 ENOG4108K2B transcriptional regulator FDZ86_RS25330 ENOG4105CXN decarboxylase FDZ86_RS25335 ENOG4106ZGR Transcriptional regulator FDZ86_RS25340 ENOG4105D5Q Arginine ornithine antiporter FDZ86_RS25345 ENOG4105DIJ Phosphoethanolamine transferase FDZ86_RS25350 ENOG4105XJC Two component transcriptional regulator (Winged helix family FDZ86_RS25355 ENOG4105ECM Sensor protein basS pmrB FDZ86_RS25365 ENOG4105CSH Transporter FDZ86_RS25370 ENOG4108YIV FDZ86_RS25375 ENOG4108F5E vimentin FDZ86_RS25380 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FDZ86_RS25385 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase FDZ86_RS25390 ENOG4105D5T phosphonate abc transporter FDZ86_RS25395 ENOG4105EHI Phosphonate ABC transporter, periplasmic FDZ86_RS25405 ENOG4107RJJ Transcriptional regulator FDZ86_RS25410 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG FDZ86_RS25415 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH FDZ86_RS25420 ENOG4105EKV Phosphonate metabolism protein FDZ86_RS25425 ENOG4105FT8 Phosphonate metabolism FDZ86_RS25430 ENOG4105ENV phosphonate C-P lyase system protein PhnK FDZ86_RS25435 ENOG4105HRV phosphonate c-p lyase system protein phnl FDZ86_RS25440 ENOG4105FD8 phosphonate metabolism protein PhnM FDZ86_RS25445 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) FDZ86_RS25450 ENOG410849A acetyltransferase, (GNAT) family FDZ86_RS25455 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein FDZ86_RS25460 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 FDZ86_RS25470 ENOG4105C2J ABC transporter FDZ86_RS25475 ENOG4105CNN ABC, transporter FDZ86_RS25480 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FDZ86_RS25490 ENOG4105D2N Aldolase FDZ86_RS25505 ENOG4105EUZ Beta-lactamase domain protein FDZ86_RS25515 ENOG4105J12 Multidrug resistance protein mdtN FDZ86_RS25520 ENOG4108MI0 Resistance protein FDZ86_RS25525 ENOG4105ETP RND efflux system, outer membrane lipoprotein FDZ86_RS25535 ENOG41082ND Uncharacterized protein yjcO FDZ86_RS25540 ENOG4105CK2 sodium dicarboxylate symporter FDZ86_RS25545 ENOG4108W0S formate-dependent nitrite reductase complex FDZ86_RS25555 ENOG4108QKW cytochrome c-type biogenesis protein FDZ86_RS25560 ENOG4105DVI reductase, NrfD FDZ86_RS25565 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FDZ86_RS25570 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit FDZ86_RS25580 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FDZ86_RS25585 ENOG41062QD Membrane FDZ86_RS25600 ENOG4105EEQ Na H antiporter FDZ86_RS25605 ENOG4105C7N Xanthine uracil vitamin C permease FDZ86_RS25610 ENOG4108Z4X TRANSCRIPTIONal FDZ86_RS25615 ENOG4108W3Q Transcriptional regulator FDZ86_RS25620 ENOG4108M8H domain protein FDZ86_RS25625 ENOG4105PMV Membrane FDZ86_RS25630 ENOG4108UUM single-stranded DNA-binding protein FDZ86_RS25635 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FDZ86_RS25640 ENOG4105MSB protein, conserved in bacteria FDZ86_RS25645 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FDZ86_RS25650 ENOG4105F0S class B acid phosphatase FDZ86_RS25660 ENOG4105CGF Aromatic amino acid aminotransferase FDZ86_RS25665 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FDZ86_RS25670 ENOG4105CDU Replicative dna helicase FDZ86_RS25675 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FDZ86_RS25680 ENOG4105P4Z Phage shock protein G FDZ86_RS25685 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FDZ86_RS25695 ENOG4106FE3 DNA repair FDZ86_RS25725 ENOG4108X9F tail fiber protein FDZ86_RS25745 ENOG4108R7K Metal Dependent Phosphohydrolase FDZ86_RS25750 ENOG41077V0 CPS-53 (KpLE1) prophage FDZ86_RS25785 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FDZ86_RS25795 ENOG4105MYN Zinc uptake regulation protein FDZ86_RS25800 ENOG4105VDW Csbd family FDZ86_RS25805 ENOG4107R73 Mate efflux family protein FDZ86_RS25815 ENOG41080IJ Diacylglycerol kinase FDZ86_RS25840 ENOG4107W52 maltose operon periplasmic protein FDZ86_RS25850 ENOG4108IJ9 (ABC) transporter FDZ86_RS25855 ENOG4107FKK extracellular solute-binding protein family 1 FDZ86_RS25860 ENOG4105D56 permease protein FDZ86_RS25865 ENOG4105EG2 ABC transporter, permease FDZ86_RS25890 ENOG4105E3R (LipO)protein FDZ86_RS25895 ENOG4108Q9C Periplasmic Protein FDZ86_RS25900 ENOG4108MDC (LipO)protein FDZ86_RS25910 ENOG4107QP8 phosphohexose isomerase FDZ86_RS25915 ENOG4105CFH Aspartokinase FDZ86_RS25920 ENOG4108ZR5 Conserved Protein FDZ86_RS25925 ENOG4105FE9 pseudouridine synthase FDZ86_RS25930 ENOG4105DKT Transcriptional regulator FDZ86_RS25935 ENOG4105CHR reductase FDZ86_RS25940 ENOG4108XCU pts system FDZ86_RS25945 ENOG4105KPI PTS system sorbose subfamily IIB component FDZ86_RS25950 ENOG4105ETZ PTS System FDZ86_RS25955 ENOG4105F3R pts system mannose fructose sorbose family iid FDZ86_RS25960 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FDZ86_RS25970 ENOG4105EAM Na Pi-cotransporter FDZ86_RS25975 ENOG4105C3R Methionine synthase FDZ86_RS25980 ENOG41069M3 Transcriptional regulator FDZ86_RS25995 ENOG4108I9X Isocitrate lyase FDZ86_RS26000 ENOG4107QP3 malate synthase g FDZ86_RS26010 ENOG4105K5X acetyltransferase FDZ86_RS26040 ENOG4105C12 Phosphoribosylglycinamide synthetase FDZ86_RS26045 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FDZ86_RS26050 ENOG4105BZU Histidine kinase FDZ86_RS26055 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism FDZ86_RS26060 ENOG4108T8B Protein of unknown function (DUF1481) FDZ86_RS26070 ENOG4105R2J Conserved Protein FDZ86_RS26105 ENOG4105D06 uba thif-type nad fad binding protein FDZ86_RS26110 ENOG4105WHD thiamine biosynthesis protein ThiS FDZ86_RS26115 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) FDZ86_RS26120 ENOG4105D41 biosynthesis protein thiH FDZ86_RS26125 ENOG410645W Thiamin biosynthesis protein ThiH FDZ86_RS26160 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FDZ86_RS26165 ENOG4105PM1 preprotein translocase subunit SecE FDZ86_RS26200 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase FDZ86_RS26205 ENOG4105D4A Cell wall formation (By similarity) FDZ86_RS26230 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FDZ86_RS26235 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) FDZ86_RS26240 ENOG4107R9T Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity) FDZ86_RS26245 ENOG4108Y73 Membrane FDZ86_RS26250 ENOG4105EJ2 Transcriptional regulator FDZ86_RS26260 ENOG4105CH2 amidohydrolase FDZ86_RS26270 ENOG4105C5Q Transcriptional regulator FDZ86_RS26285 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FDZ86_RS26300 ENOG4105DIJ Phosphoethanolamine transferase FDZ86_RS26305 ENOG4106R3P AraC family transcriptional regulator FDZ86_RS26310 ENOG4108XCZ PTS System FDZ86_RS26315 ENOG4108AHH pyruvate formate lyase II activase FDZ86_RS26325 ENOG4108YRF PTS System FDZ86_RS26330 ENOG4105DM4 PTS System FDZ86_RS26335 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FDZ86_RS26340 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FDZ86_RS26345 ENOG4105DCT glycerol dehydrogenase FDZ86_RS26350 ENOG4108XC3 NADH ubiquinone oxidoreductase FDZ86_RS26355 ENOG4108Q5Y Membrane FDZ86_RS26365 ENOG4105SYT Methylenetetrahydrofolate reductase FDZ86_RS26370 ENOG4105CFH Aspartokinase FDZ86_RS26375 ENOG4105C28 cystathionine FDZ86_RS26385 ENOG4107S01 Repressor protein MetJ FDZ86_RS26400 ENOG4105CNA YD repeat protein FDZ86_RS26410 ENOG4105C25 Primosomal protein n' FDZ86_RS26415 ENOG4105ETE Transcriptional regulator (LacI family FDZ86_RS26420 ENOG41063M6 Cell Division Protein FDZ86_RS26435 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FDZ86_RS26480 ENOG4105CBT Fructose-1,6-bisphosphatase FDZ86_RS26485 ENOG4105DP0 ferredoxin-NADP reductase FDZ86_RS26495 ENOG41065TG regulatoR FDZ86_RS26500 ENOG4108VTS Membrane FDZ86_RS26505 ENOG4105EBK exported protein FDZ86_RS26520 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FDZ86_RS26535 ENOG4105FMW periplasmic FDZ86_RS26540 ENOG4105E3W Two component transcriptional regulator (Winged helix family FDZ86_RS26545 ENOG4105E0F Histidine kinase FDZ86_RS26550 ENOG4108RPX mosc domain containing protein FDZ86_RS26560 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FDZ86_RS26570 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) FDZ86_RS26605 ENOG41064BA PTS system, fructose-specific, IIA component FDZ86_RS26610 ENOG4105DM4 PTS System FDZ86_RS26615 ENOG4105CN9 Peptidase m42 family protein FDZ86_RS26620 ENOG4106C3V frv operon regulatory protein FDZ86_RS26625 ENOG4108V87 frv operon regulatory protein FDZ86_RS26640 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FDZ86_RS26645 ENOG4108MG3 formate dehydrogenase FDZ86_RS26655 ENOG41068KX affects formate dehydrogenase-N FDZ86_RS26675 ENOG4105SUU thioesterase domain FDZ86_RS26690 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 FDZ86_RS26695 ENOG4105E98 transcriptional regulator DeoR family FDZ86_RS26700 ENOG4108MGF sugar kinase FDZ86_RS26705 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FDZ86_RS26710 ENOG4105D2M Aldolase FDZ86_RS26715 ENOG4107QKS N-acylglucosamine 2-epimerase FDZ86_RS26720 ENOG4107WI4 Aldose-1-epimerase FDZ86_RS26730 ENOG4105CJQ hydrolase, family 31 FDZ86_RS26735 ENOG4105CT4 transporter FDZ86_RS26740 ENOG4105CT4 transporter FDZ86_RS26745 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is FDZ86_RS26750 ENOG4105R9B Major Facilitator FDZ86_RS26755 ENOG4108KHF Resistance protein FDZ86_RS26760 ENOG4108K85 Transcriptional regulator FDZ86_RS26765 ENOG4105CI3 gtp-binding protein typa FDZ86_RS26770 ENOG4105C5F glutamine synthetase FDZ86_RS26775 ENOG4105CUX Signal transduction histidine kinase FDZ86_RS26780 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FDZ86_RS26785 ENOG4106FIY FDZ86_RS26790 ENOG4105D4P Coproporphyrinogen iii oxidase FDZ86_RS26795 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) FDZ86_RS26805 ENOG4105C2M dna polymerase I FDZ86_RS26810 ENOG4106HNH Acyl-transferase FDZ86_RS26820 ENOG4108Z33 Thiol disulfide Interchange Protein FDZ86_RS26825 ENOG4105E27 serine threonine protein kinase FDZ86_RS26830 ENOG4105PC1 Conserved Protein FDZ86_RS26835 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FDZ86_RS26840 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b FDZ86_RS26870 ENOG4108RR8 protoporphyrinogen oxidase FDZ86_RS26875 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FDZ86_RS26880 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FDZ86_RS26895 ENOG4105CHU acetyl-coa acetyltransferase FDZ86_RS26900 ENOG4108EX3 reductase FDZ86_RS26905 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FDZ86_RS26910 ENOG4105MDZ Transcriptional activator rfaH FDZ86_RS26915 ENOG4105F8V Hydrolase, tatD family FDZ86_RS26920 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FDZ86_RS26925 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) FDZ86_RS26930 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FDZ86_RS26940 ENOG4105JC1 sterol-binding domain protein FDZ86_RS26950 ENOG4105CGY Dna recombination protein FDZ86_RS26955 ENOG4108I5U Uridine phosphorylase FDZ86_RS26960 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) FDZ86_RS26970 ENOG4105DZ2 Transcriptional regulator FDZ86_RS26975 ENOG4105EMK carboxylate amino acid amine transporter FDZ86_RS26980 ENOG4105DQF Hydrolase FDZ86_RS26985 ENOG4108EUD Lysophospholipase FDZ86_RS26990 ENOG410829K Lysine exporter protein (Lyse ygga) FDZ86_RS26995 ENOG4105CCF Lysine exporter protein (Lyse ygga) FDZ86_RS27000 ENOG4105C9U ATP-dependent DNA helicase RecQ FDZ86_RS27005 ENOG4105HDD phospholipase FDZ86_RS27010 ENOG4108VUY thioesterase Superfamily protein FDZ86_RS27015 ENOG4105FR1 rard protein FDZ86_RS27025 ENOG4107QUT magnesium and cobalt transport protein CorA FDZ86_RS27040 ENOG4107QUT magnesium and cobalt transport protein CorA FDZ86_RS27045 ENOG4108T58 Mg2 transport protein CorA FDZ86_RS27050 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase FDZ86_RS27055 ENOG4105C4R Atp-dependent dna helicase FDZ86_RS27060 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant FDZ86_RS27070 ENOG4105CT0 Protein of unknown function, DUF484 FDZ86_RS27080 ENOG4105S7Z (LipO)protein FDZ86_RS27090 ENOG4107T0K Adenylate cyclase FDZ86_RS27100 ENOG41076E6 Uroporphyrinogen-III Synthase FDZ86_RS27105 ENOG4105ECF c-methyltransferase FDZ86_RS27110 ENOG410601J HemY protein FDZ86_RS27115 ENOG4105ENH Sulfatase FDZ86_RS27120 ENOG4105C4X radical SAM domain protein FDZ86_RS27145 ENOG4105C85 amino acid FDZ86_RS27165 ENOG4105EGZ biosynthesis protein FDZ86_RS27170 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FDZ86_RS27175 ENOG4108WJ1 acetyltransferase FDZ86_RS27180 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FDZ86_RS27185 ENOG4105C1B dTDP-glucose 4-6-dehydratase FDZ86_RS27190 ENOG4107QQG Dehydrogenase FDZ86_RS27195 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FDZ86_RS27200 ENOG4105SFE lipopolysaccharide biosynthesis protein FDZ86_RS27205 ENOG4105ESV Glycosyl transferase, family 4 FDZ86_RS27210 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FDZ86_RS27235 ENOG4105C4R Atp-dependent dna helicase FDZ86_RS27245 ENOG4105KQ5 peptidylprolyl cis-trans isomerase FDZ86_RS27255 ENOG4105EMY transcriptional regulator FDZ86_RS27260 ENOG4105C7B Threonine dehydratase FDZ86_RS27270 ENOG4105CM2 brancheD-chain amino acid aminotransferase FDZ86_RS27275 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit FDZ86_RS27295 ENOG4105C0P Mg chelatase subunit ChlI FDZ86_RS27300 ENOG4108WFC UPF0438 protein yifE FDZ86_RS27340 ENOG4107EJG GntR family transcriptional regulator FDZ86_RS27345 ENOG4105C0R drug resistance transporter emrb qaca subfamily FDZ86_RS27350 ENOG4105ETE Transcriptional regulator (LacI family FDZ86_RS27355 ENOG4108RVA ribokinase FDZ86_RS27360 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FDZ86_RS27365 ENOG4105CNN ABC, transporter FDZ86_RS27370 ENOG4105C2J ABC transporter FDZ86_RS27375 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) FDZ86_RS27380 ENOG4105DFH Transport of potassium into the cell (By similarity) FDZ86_RS27390 ENOG4105EV2 VWA domain protein interacting with AAA ATPase FDZ86_RS27400 ENOG4108VVK transcriptional Regulator, AsnC FDZ86_RS27405 ENOG4105QTB Flavodoxin FDZ86_RS27410 ENOG4108MA4 Peptidase M66 FDZ86_RS27425 ENOG4107QHF type ii secretion system protein e FDZ86_RS27430 ENOG4105D7Q type ii secretion system FDZ86_RS27440 ENOG4105PBE general secretion pathway protein h FDZ86_RS27485 ENOG4108RC6 RTX toxin FDZ86_RS27490 ENOG4107V48 Hemolysin-type calcium-binding FDZ86_RS27495 ENOG4108JJA ABC, transporter FDZ86_RS27500 ENOG4105C42 Type I secretion membrane fusion protein (HlyD FDZ86_RS27520 ENOG4106JVB Replication Protein FDZ86_RS27595 ENOG41073YN Protein of unknown function (DUF1380) FDZ86_RS27665 ENOG4105FEQ ParB domain protein nuclease FDZ86_RS27715 ENOG4108N67 choline binding protein FDZ86_RS27740 ENOG4108YXQ IS66 Orf2 family protein FDZ86_RS27745 ENOG4105E5H Transposase FDZ86_RS27760 ENOG4107U2T alpha beta FDZ86_RS27765 ENOG4107CBI conjugal transfer fertility inhibition protein FDZ86_RS27775 ENOG4105KK6 nuclease FDZ86_RS27790 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) FDZ86_RS27800 ENOG4106CQM replication FDZ86_RS27840 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) FDZ86_RS27855 ENOG4105I1J Autotransporter FDZ86_RS27865 ENOG4107BJW polysaccharide deacetylase FDZ86_RS27870 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FDZ86_RS27875 ENOG4105DIJ Phosphoethanolamine transferase FDZ86_RS27880 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase FDZ86_RS28015 ENOG4108V42 Type IV secretion system protein VirB8 FDZ86_RS28060 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)