locus-tag	class	description
IMX21_RS00195	COG3842	ATPase activity
IMX21_RS00205	COG2850	peptidyl-arginine hydroxylation
IMX21_RS00315	COG1802	Transcriptional regulator
IMX21_RS00315	COG4626	Terminase
IMX21_RS00325	COG2205	protein histidine kinase activity
IMX21_RS00330	COG0745	RESPONSE REGULATOR receiver
IMX21_RS00335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMX21_RS00345	COG0482	sulfurtransferase activity
IMX21_RS00355	COG1187	pseudouridine synthase activity
IMX21_RS00360	COG0538	isocitrate dehydrogenase activity
IMX21_RS00365	COG0582	viral genome integration into host DNA
IMX21_RS00390	COG2076	Multidrug Resistance protein
IMX21_RS00400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IMX21_RS00420	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IMX21_RS00455	COG5562	phage envelope protein
IMX21_RS00470	COG4220	transposase activity
IMX21_RS00490	COG1030	water channel activity
IMX21_RS00540	COG1196	nuclear chromosome segregation
IMX21_RS00575	COG5301	cellulose 1,4-beta-cellobiosidase activity
IMX21_RS00580	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IMX21_RS00585	COG3546	catalase activity
IMX21_RS00590	COG3685	Protein conserved in bacteria
IMX21_RS00595	COG3685	Protein conserved in bacteria
IMX21_RS00600	COG3729	General stress protein
IMX21_RS00605	COG0500	methyltransferase
IMX21_RS00620	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS00625	COG4372	Transposase
IMX21_RS00635	COG4571	Outer membrane protease
IMX21_RS00665	COG2894	cell division
IMX21_RS00695	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMX21_RS00710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMX21_RS00715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMX21_RS00720	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IMX21_RS00735	COG2719	SpoVR family
IMX21_RS00745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMX21_RS00755	COG1619	proteins homologs of microcin C7 resistance protein MccF
IMX21_RS00790	COG0157	Belongs to the NadC ModD family
IMX21_RS00800	COG1120	ATPase activity
IMX21_RS00805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMX21_RS00810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMX21_RS00820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMX21_RS00820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS00820	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IMX21_RS00825	COG1461	Dihydroxyacetone kinase
IMX21_RS00830	COG2376	Dihydroxyacetone kinase
IMX21_RS00840	COG0012	GTP binding
IMX21_RS00855	COG0659	secondary active sulfate transmembrane transporter activity
IMX21_RS00860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMX21_RS00890	COG3094	Invasion gene expression up-regulator, SirB
IMX21_RS00895	COG2912	Transglutaminase-like superfamily
IMX21_RS00915	COG0387	Pfam Sodium calcium exchanger
IMX21_RS00920	COG4572	Cation transport regulator
IMX21_RS00925	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IMX21_RS00930	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IMX21_RS00935	COG4932	domain protein
IMX21_RS00940	COG2197	response regulator
IMX21_RS00945	COG3850	Histidine kinase
IMX21_RS00950	COG2223	nitrite transmembrane transporter activity
IMX21_RS00955	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IMX21_RS00960	COG1140	nitrate reductase beta subunit
IMX21_RS00965	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IMX21_RS00970	COG2181	nitrate reductase activity
IMX21_RS01000	COG0788	formyltetrahydrofolate deformylase activity
IMX21_RS01010	COG1752	Esterase of the alpha-beta hydrolase superfamily
IMX21_RS01015	COG0745	RESPONSE REGULATOR receiver
IMX21_RS01020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMX21_RS01030	COG1435	thymidine kinase activity
IMX21_RS01035	COG1012	belongs to the aldehyde dehydrogenase family
IMX21_RS01035	COG1454	alcohol dehydrogenase
IMX21_RS01040	COG2095	MarC family integral membrane protein
IMX21_RS01045	COG4166	transmembrane transport
IMX21_RS01050	COG0601	transmembrane transport
IMX21_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMX21_RS01060	COG0444	Belongs to the ABC transporter superfamily
IMX21_RS01065	COG4608	Belongs to the ABC transporter superfamily
IMX21_RS01085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IMX21_RS01090	COG2350	Protein conserved in bacteria
IMX21_RS01095	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IMX21_RS01100	COG1607	acyl-coa hydrolase
IMX21_RS01120	COG3047	cAMP biosynthetic process
IMX21_RS01125	COG0582	viral genome integration into host DNA
IMX21_RS01135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX21_RS01170	COG1396	sequence-specific DNA binding
IMX21_RS01195	COG1846	Transcriptional regulator
IMX21_RS01225	COG1403	HNH endonuclease
IMX21_RS01230	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IMX21_RS01275	COG3772	lysozyme
IMX21_RS01400	COG5301	cellulose 1,4-beta-cellobiosidase activity
IMX21_RS01445	COG4372	Transposase
IMX21_RS01450	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS01500	COG3685	Protein conserved in bacteria
IMX21_RS01505	COG3685	Protein conserved in bacteria
IMX21_RS01510	COG3729	General stress protein
IMX21_RS01525	COG0134	indole-3-glycerol-phosphate synthase activity
IMX21_RS01525	COG0135	phosphoribosylanthranilate isomerase activity
IMX21_RS01530	COG0512	Glutamine amidotransferase of anthranilate synthase
IMX21_RS01530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMX21_RS01535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMX21_RS01545	COG0613	PHP domain protein
IMX21_RS01550	COG0009	L-threonylcarbamoyladenylate synthase
IMX21_RS01555	COG4907	membrane protein (DUF2207)
IMX21_RS01560	COG1187	pseudouridine synthase activity
IMX21_RS01565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IMX21_RS01570	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS01575	COG0616	signal peptide processing
IMX21_RS01585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMX21_RS01590	COG0583	DNA-binding transcription factor activity
IMX21_RS01610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMX21_RS01620	COG0671	phosphoesterase, PA-phosphatase related
IMX21_RS01625	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IMX21_RS01630	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IMX21_RS01640	COG0023	Translation Initiation Factor
IMX21_RS01650	COG1349	DNA-binding transcription factor activity
IMX21_RS01660	COG5001	Diguanylate cyclase
IMX21_RS01670	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMX21_RS01670	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMX21_RS01675	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMX21_RS01685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMX21_RS01700	COG2814	Major facilitator Superfamily
IMX21_RS01705	COG4172	Belongs to the ABC transporter superfamily
IMX21_RS01710	COG4172	Belongs to the ABC transporter superfamily
IMX21_RS01715	COG4171	peptide transport system, permease
IMX21_RS01720	COG4168	peptide transport system, permease
IMX21_RS01725	COG4166	transmembrane transport
IMX21_RS01735	COG0531	amino acid
IMX21_RS01745	COG0174	glutamine synthetase
IMX21_RS01750	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IMX21_RS01755	COG1396	sequence-specific DNA binding
IMX21_RS01755	COG1917	Cupin 2, conserved barrel domain protein
IMX21_RS01760	COG1012	belongs to the aldehyde dehydrogenase family
IMX21_RS01765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMX21_RS01770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMX21_RS01775	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IMX21_RS01780	COG1842	Phage shock protein A
IMX21_RS01790	COG1983	PspC domain protein
IMX21_RS01800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMX21_RS01815	COG1175	transmembrane transport
IMX21_RS01820	COG0395	ABC-type sugar transport system, permease component
IMX21_RS01825	COG1063	alcohol dehydrogenase
IMX21_RS01830	COG1082	Xylose isomerase domain protein TIM barrel
IMX21_RS01835	COG0673	inositol 2-dehydrogenase activity
IMX21_RS01840	COG1554	hydrolase, family 65, central catalytic
IMX21_RS01845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMX21_RS01850	COG3842	ATPase activity
IMX21_RS01860	COG1609	Transcriptional regulator
IMX21_RS01865	COG3106	COG3106 Predicted ATPase
IMX21_RS01875	COG3283	Transcriptional regulator of aromatic amino acids metabolism
IMX21_RS01880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMX21_RS01885	COG4948	Mandelate Racemase Muconate Lactonizing
IMX21_RS01890	COG2866	Carboxypeptidase
IMX21_RS01895	COG0702	epimerase
IMX21_RS01905	COG1073	alpha beta
IMX21_RS01910	COG0583	DNA-binding transcription factor activity
IMX21_RS01915	COG4166	transmembrane transport
IMX21_RS01920	COG0668	transmembrane transport
IMX21_RS01925	COG3182	Iron-regulated membrane protein
IMX21_RS01930	COG0589	response to stress
IMX21_RS01935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMX21_RS01940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMX21_RS01960	COG1473	amidohydrolase
IMX21_RS01965	COG1473	amidohydrolase
IMX21_RS01970	COG0583	DNA-binding transcription factor activity
IMX21_RS01975	COG2840	Smr protein MutS2
IMX21_RS01980	COG3706	GGDEF domain
IMX21_RS01995	COG0513	Belongs to the DEAD box helicase family
IMX21_RS02005	COG0582	viral genome integration into host DNA
IMX21_RS02025	COG3723	Recombinational DNA repair protein, rece pathway
IMX21_RS02030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX21_RS02080	COG3756	Protein conserved in bacteria
IMX21_RS02085	COG1484	DNA-dependent DNA replication
IMX21_RS02090	COG1846	Transcriptional regulator
IMX21_RS02190	COG3772	lysozyme
IMX21_RS02320	COG5301	cellulose 1,4-beta-cellobiosidase activity
IMX21_RS02345	COG4372	Transposase
IMX21_RS02350	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS02440	COG1846	Transcriptional regulator
IMX21_RS02475	COG3111	PFAM Bacterial OB fold (BOF) protein
IMX21_RS02485	COG1403	HNH endonuclease
IMX21_RS02490	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IMX21_RS02505	COG2207	Transcriptional regulator
IMX21_RS02545	COG3772	lysozyme
IMX21_RS02575	COG4220	transposase activity
IMX21_RS02595	COG1030	water channel activity
IMX21_RS02685	COG5301	cellulose 1,4-beta-cellobiosidase activity
IMX21_RS02720	COG0246	Mannitol dehydrogenase
IMX21_RS02730	COG1802	Transcriptional regulator
IMX21_RS02735	COG4221	oxidoreductase activity
IMX21_RS02740	COG0339	signal peptide processing
IMX21_RS02745	COG1546	Belongs to the CinA family
IMX21_RS02750	COG3111	PFAM Bacterial OB fold (BOF) protein
IMX21_RS02755	COG3706	GGDEF domain
IMX21_RS02775	COG2814	Major facilitator Superfamily
IMX21_RS02780	COG0697	spore germination
IMX21_RS02790	COG4977	sequence-specific DNA binding
IMX21_RS02795	COG1846	Transcriptional regulator
IMX21_RS02800	COG2095	MarC family integral membrane protein
IMX21_RS02805	COG2814	Major facilitator Superfamily
IMX21_RS02815	COG0583	DNA-binding transcription factor activity
IMX21_RS02820	COG1012	belongs to the aldehyde dehydrogenase family
IMX21_RS02825	COG2066	Belongs to the glutaminase family
IMX21_RS02835	COG2199	diguanylate cyclase activity
IMX21_RS02845	COG3781	membrane
IMX21_RS02860	COG1830	Aldolase
IMX21_RS02870	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS02875	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS02880	COG1129	ABC transporter
IMX21_RS02890	COG1070	Carbohydrate kinase
IMX21_RS02895	COG3210	domain, Protein
IMX21_RS02895	COG2911	Protein conserved in bacteria
IMX21_RS02915	COG3539	Fimbrial protein
IMX21_RS02925	COG3188	usher protein
IMX21_RS02930	COG3539	Fimbrial protein
IMX21_RS02935	COG3539	Fimbrial protein
IMX21_RS02940	COG3539	Fimbrial protein
IMX21_RS02945	COG0243	molybdopterin cofactor binding
IMX21_RS02955	COG2207	Transcriptional regulator
IMX21_RS02960	COG3119	arylsulfatase activity
IMX21_RS02965	COG0641	radical SAM
IMX21_RS02975	COG4178	(ABC) transporter
IMX21_RS02980	COG4771	TonB-dependent receptor
IMX21_RS02985	COG0612	Peptidase, M16
IMX21_RS02990	COG0076	glutamate decarboxylase activity
IMX21_RS02995	COG0531	amino acid
IMX21_RS03000	COG1649	PFAM Uncharacterised BCR, COG1649
IMX21_RS03010	COG3706	GGDEF domain
IMX21_RS03020	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IMX21_RS03025	COG0747	negative chemotaxis
IMX21_RS03030	COG0601	transmembrane transport
IMX21_RS03035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMX21_RS03040	COG0444	Belongs to the ABC transporter superfamily
IMX21_RS03045	COG4608	Belongs to the ABC transporter superfamily
IMX21_RS03050	COG1764	response to oxidative stress
IMX21_RS03070	COG1064	alcohol dehydrogenase
IMX21_RS03075	COG3093	addiction module antidote protein HigA
IMX21_RS03080	COG2864	formate dehydrogenase
IMX21_RS03085	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS03095	COG0697	spore germination
IMX21_RS03110	COG4886	Leucine-rich repeat (LRR) protein
IMX21_RS03115	COG4886	Leucine-rich repeat (LRR) protein
IMX21_RS03120	COG2223	nitrite transmembrane transporter activity
IMX21_RS03125	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IMX21_RS03130	COG1140	nitrate reductase beta subunit
IMX21_RS03135	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IMX21_RS03140	COG2181	nitrate reductase activity
IMX21_RS03145	COG0384	phenazine biosynthesis protein PhzF
IMX21_RS03155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMX21_RS03185	COG3209	COG3209 Rhs family protein
IMX21_RS03200	COG0625	glutathione transferase activity
IMX21_RS03205	COG1113	amino acid transport
IMX21_RS03210	COG3391	amine dehydrogenase activity
IMX21_RS03215	COG4772	TonB-dependent receptor
IMX21_RS03220	COG1802	Transcriptional regulator
IMX21_RS03225	COG2130	NADP-dependent
IMX21_RS03230	COG1247	-acetyltransferase
IMX21_RS03235	COG3238	Protein conserved in bacteria
IMX21_RS03260	COG1177	transmembrane transport
IMX21_RS03265	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMX21_RS03270	COG3842	ATPase activity
IMX21_RS03275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IMX21_RS03280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMX21_RS03285	COG1598	PFAM Uncharacterised protein family UPF0150
IMX21_RS03290	COG1724	mRNA binding
IMX21_RS03300	COG0826	peptidase U32
IMX21_RS03305	COG1396	sequence-specific DNA binding
IMX21_RS03310	COG3135	benzoate transporter
IMX21_RS03320	COG0500	methyltransferase
IMX21_RS03325	COG1275	C4-dicarboxylate transporter malic acid transport protein
IMX21_RS03330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IMX21_RS03340	COG2841	Protein conserved in bacteria
IMX21_RS03350	COG5383	Protein conserved in bacteria
IMX21_RS03355	COG0583	DNA-binding transcription factor activity
IMX21_RS03360	COG0840	transmembrane signaling receptor activity
IMX21_RS03375	COG3038	cytochrome b561
IMX21_RS03380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMX21_RS03385	COG1012	belongs to the aldehyde dehydrogenase family
IMX21_RS03390	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IMX21_RS03415	COG1643	Atp-dependent helicase
IMX21_RS03420	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IMX21_RS03425	COG2453	phosphatase
IMX21_RS03425	COG0671	phosphoesterase, PA-phosphatase related
IMX21_RS03430	COG2267	carboxylic ester hydrolase activity
IMX21_RS03435	COG4589	Belongs to the CDS family
IMX21_RS03440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMX21_RS03450	COG0667	Aldo Keto reductase
IMX21_RS03465	COG3784	Protein of unknown function (DUF1318)
IMX21_RS03475	COG2911	Protein conserved in bacteria
IMX21_RS03480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMX21_RS03485	COG3187	Heat shock protein
IMX21_RS03490	COG3042	response to heat
IMX21_RS03495	COG1013	pyruvate-flavodoxin oxidoreductase activity
IMX21_RS03495	COG0674	pyruvate-flavodoxin oxidoreductase activity
IMX21_RS03495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMX21_RS03495	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IMX21_RS03505	COG0589	response to stress
IMX21_RS03530	COG5301	cellulose 1,4-beta-cellobiosidase activity
IMX21_RS03545	COG2032	superoxide dismutase activity
IMX21_RS03660	COG3772	lysozyme
IMX21_RS03710	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IMX21_RS03715	COG1403	HNH endonuclease
IMX21_RS03750	COG1484	DNA-dependent DNA replication
IMX21_RS03755	COG1846	Transcriptional regulator
IMX21_RS03805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX21_RS03830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMX21_RS03845	COG0243	molybdopterin cofactor binding
IMX21_RS03850	COG0243	molybdopterin cofactor binding
IMX21_RS03855	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS03860	COG3302	dmso reductase anchor subunit
IMX21_RS03865	COG3381	protein complex oligomerization
IMX21_RS03875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IMX21_RS03880	COG1940	carbohydrate kinase activity
IMX21_RS03885	COG0583	DNA-binding transcription factor activity
IMX21_RS03890	COG2814	Major facilitator Superfamily
IMX21_RS03905	COG3591	Belongs to the peptidase S1B family
IMX21_RS03920	COG0628	permease
IMX21_RS03925	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IMX21_RS03930	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IMX21_RS03940	COG0531	amino acid
IMX21_RS03950	COG3136	membrane protein required for alginate biosynthesis
IMX21_RS03955	COG0745	RESPONSE REGULATOR receiver
IMX21_RS03960	COG2205	protein histidine kinase activity
IMX21_RS03970	COG0114	fumarate hydratase activity
IMX21_RS03975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IMX21_RS03975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IMX21_RS03980	COG1482	cell wall glycoprotein biosynthetic process
IMX21_RS03985	COG5339	Protein conserved in bacteria
IMX21_RS04005	COG1309	transcriptional regulator
IMX21_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS04015	COG1609	Transcriptional regulator
IMX21_RS04020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX21_RS04020	COG1263	PTS System
IMX21_RS04025	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IMX21_RS04035	COG0673	inositol 2-dehydrogenase activity
IMX21_RS04065	COG4656	Part of a membrane complex involved in electron transport
IMX21_RS04075	COG4659	FMN binding
IMX21_RS04085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMX21_RS04090	COG3104	oligopeptide transport
IMX21_RS04095	COG0625	glutathione transferase activity
IMX21_RS04100	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IMX21_RS04115	COG3895	Periplasmic Protein
IMX21_RS04125	COG3133	Outer membrane lipoprotein
IMX21_RS04140	COG1566	PFAM secretion protein HlyD family protein
IMX21_RS04145	COG1289	transmembrane transporter activity
IMX21_RS04150	COG2032	superoxide dismutase activity
IMX21_RS04160	COG3313	Fe-S protein
IMX21_RS04165	COG1309	transcriptional regulator
IMX21_RS04170	COG1902	pentaerythritol trinitrate reductase activity
IMX21_RS04175	COG0346	lactoylglutathione lyase activity
IMX21_RS04185	COG1201	RNA secondary structure unwinding
IMX21_RS04190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IMX21_RS04195	COG0791	NLP P60 protein
IMX21_RS04200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMX21_RS04205	COG2814	Major facilitator Superfamily
IMX21_RS04220	COG0583	DNA-binding transcription factor activity
IMX21_RS04225	COG2814	Major facilitator Superfamily
IMX21_RS04230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IMX21_RS04235	COG0307	riboflavin synthase, alpha
IMX21_RS04245	COG3468	outer membrane autotransporter barrel domain protein
IMX21_RS04265	COG4529	Protein conserved in bacteria
IMX21_RS04275	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IMX21_RS04280	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS04290	COG2414	aldehyde ferredoxin oxidoreductase
IMX21_RS04295	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS04305	COG0469	pyruvate kinase activity
IMX21_RS04310	COG4238	major outer membrane lipoprotein
IMX21_RS04315	COG1376	ErfK ybiS ycfS ynhG family protein
IMX21_RS04330	COG0719	Fe-S assembly protein
IMX21_RS04335	COG0396	ATPase activity
IMX21_RS04340	COG0719	Fe-S assembly protein
IMX21_RS04345	COG0316	Belongs to the HesB IscA family
IMX21_RS04355	COG2050	protein possibly involved in aromatic compounds catabolism
IMX21_RS04360	COG0277	FAD linked oxidase domain protein
IMX21_RS04360	COG0247	lactate metabolic process
IMX21_RS04365	COG0628	permease
IMX21_RS04380	COG0738	Major facilitator superfamily
IMX21_RS04385	COG2271	Major facilitator Superfamily
IMX21_RS04400	COG4670	ketone body catabolic process
IMX21_RS04405	COG1960	acyl-CoA dehydrogenase activity
IMX21_RS04410	COG2207	Transcriptional regulator
IMX21_RS04410	COG1917	Cupin 2, conserved barrel domain protein
IMX21_RS04415	COG2086	electron transfer activity
IMX21_RS04420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IMX21_RS04425	COG0644	oxidoreductase
IMX21_RS04430	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IMX21_RS04435	COG0318	PFAM AMP-dependent synthetase and ligase
IMX21_RS04440	COG0574	Belongs to the PEP-utilizing enzyme family
IMX21_RS04440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMX21_RS04450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMX21_RS04455	COG4256	Hemin uptake protein
IMX21_RS04465	COG2200	EAL domain
IMX21_RS04470	COG0791	NLP P60 protein
IMX21_RS04480	COG0386	Belongs to the glutathione peroxidase family
IMX21_RS04495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMX21_RS04495	COG0072	phenylalanine-tRNA ligase activity
IMX21_RS04540	COG3137	Salt-induced outer membrane protein
IMX21_RS04545	COG1105	Belongs to the carbohydrate kinase PfkB family
IMX21_RS04555	COG3001	Fructosamine kinase
IMX21_RS04565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMX21_RS04570	COG1988	membrane-bound metal-dependent
IMX21_RS04575	COG1823	symporter activity
IMX21_RS04590	COG0753	catalase activity
IMX21_RS04600	COG1486	melibiose metabolic process
IMX21_RS04605	COG2169	Transcriptional regulator
IMX21_RS04605	COG1917	Cupin 2, conserved barrel domain protein
IMX21_RS04610	COG1447	Phosphotransferase system cellobiose-specific component IIA
IMX21_RS04615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX21_RS04620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX21_RS04625	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMX21_RS04635	COG0322	excinuclease ABC activity
IMX21_RS04645	COG3678	ATP-independent chaperone mediated protein folding
IMX21_RS04675	COG0708	Exodeoxyribonuclease III
IMX21_RS04680	COG0398	Pfam SNARE associated Golgi protein
IMX21_RS04690	COG0398	Pfam SNARE associated Golgi protein
IMX21_RS04695	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMX21_RS04700	COG4134	Bacterial extracellular solute-binding protein
IMX21_RS04705	COG4135	transport system, permease component
IMX21_RS04710	COG4136	ATPase activity
IMX21_RS04715	COG2897	thiosulfate sulfurtransferase activity
IMX21_RS04720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMX21_RS04725	COG0494	nUDIX hydrolase
IMX21_RS04735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMX21_RS04745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMX21_RS04750	COG0709	Synthesizes selenophosphate from selenide and ATP
IMX21_RS04755	COG0778	Nitroreductase
IMX21_RS04760	COG0616	signal peptide processing
IMX21_RS04770	COG0252	asparaginase activity
IMX21_RS04775	COG1335	isochorismatase
IMX21_RS04790	COG1349	DNA-binding transcription factor activity
IMX21_RS04795	COG0667	Aldo Keto reductase
IMX21_RS04800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX21_RS04805	COG0191	fructose-bisphosphate aldolase activity
IMX21_RS04810	COG1063	alcohol dehydrogenase
IMX21_RS04815	COG2271	Major facilitator Superfamily
IMX21_RS04820	COG1063	alcohol dehydrogenase
IMX21_RS04825	COG3139	Protein of unknown function (DUF1315)
IMX21_RS04835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMX21_RS04840	COG0676	glucose-6-phosphate 1-epimerase activity
IMX21_RS04845	COG0656	L-ascorbic acid biosynthetic process
IMX21_RS04850	COG3713	MltA-interacting MipA family protein
IMX21_RS04855	COG2766	serine protein kinase
IMX21_RS04865	COG2199	diguanylate cyclase activity
IMX21_RS04870	COG2199	diguanylate cyclase activity
IMX21_RS04875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMX21_RS04890	COG2207	Transcriptional regulator
IMX21_RS04895	COG2807	transmembrane transport
IMX21_RS04900	COG3189	MarR family transcriptional regulator
IMX21_RS04905	COG3042	response to heat
IMX21_RS04925	COG2261	transglycosylase associated protein
IMX21_RS04935	COG3615	Tellurite resistance protein tehB
IMX21_RS04940	COG1280	lysine exporter protein (LysE YggA)
IMX21_RS04945	COG0583	DNA-binding transcription factor activity
IMX21_RS04950	COG0473	3-isopropylmalate dehydrogenase activity
IMX21_RS04955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IMX21_RS04960	COG4638	Rieske (2fe-2S)
IMX21_RS04965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMX21_RS04970	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IMX21_RS04975	COG0318	PFAM AMP-dependent synthetase and ligase
IMX21_RS04980	COG3065	identical protein binding
IMX21_RS04985	COG1214	PFAM Peptidase M22, glycoprotease
IMX21_RS04990	COG1199	ATP-dependent helicase activity
IMX21_RS04995	COG0251	oxidation-reduction process
IMX21_RS05010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMX21_RS05020	COG1760	l-serine dehydratase
IMX21_RS05025	COG2200	EAL domain
IMX21_RS05035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX21_RS05035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS05040	COG3715	PTS system
IMX21_RS05045	COG3716	PTS system mannose fructose sorbose family IID component
IMX21_RS05060	COG2226	methyltransferase
IMX21_RS05090	COG1414	Transcriptional regulator
IMX21_RS05105	COG0793	Belongs to the peptidase S41A family
IMX21_RS05115	COG1956	GAF domain-containing protein
IMX21_RS05120	COG2995	paraquat-inducible protein a
IMX21_RS05125	COG3008	intermembrane lipid transfer
IMX21_RS05145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IMX21_RS05155	COG1276	copper resistance
IMX21_RS05160	COG2372	response to copper ion
IMX21_RS05170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMX21_RS05175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX21_RS05180	COG1770	oligopeptidase
IMX21_RS05185	COG2979	Protein of unknown function (DUF533)
IMX21_RS05195	COG3141	response to X-ray
IMX21_RS05200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IMX21_RS05205	COG0800	Aldolase
IMX21_RS05210	COG0129	dihydroxy-acid dehydratase activity
IMX21_RS05215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IMX21_RS05220	COG1737	Transcriptional regulator
IMX21_RS05225	COG0469	pyruvate kinase activity
IMX21_RS05230	COG1560	Kdo2-lipid A biosynthetic process
IMX21_RS05235	COG0739	heme binding
IMX21_RS05240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IMX21_RS05250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMX21_RS05280	COG0217	transcriptional regulatory protein
IMX21_RS05285	COG0494	nUDIX hydrolase
IMX21_RS05290	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMX21_RS05295	COG1335	isochorismatase
IMX21_RS05300	COG1801	Protein of unknown function DUF72
IMX21_RS05305	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IMX21_RS05320	COG0243	molybdopterin cofactor binding
IMX21_RS05325	COG3005	denitrification pathway
IMX21_RS05335	COG3102	Protein conserved in bacteria
IMX21_RS05345	COG3755	Protein conserved in bacteria
IMX21_RS05355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMX21_RS05360	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMX21_RS05370	COG0745	RESPONSE REGULATOR receiver
IMX21_RS05375	COG2201	protein-glutamate methylesterase activity
IMX21_RS05380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IMX21_RS05385	COG0840	transmembrane signaling receptor activity
IMX21_RS05390	COG0840	transmembrane signaling receptor activity
IMX21_RS05395	COG0835	chemotaxis
IMX21_RS05400	COG0643	Histidine kinase
IMX21_RS05400	COG2198	Histidine kinase
IMX21_RS05405	COG1360	Flagellar Motor Protein
IMX21_RS05410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IMX21_RS05425	COG0589	response to stress
IMX21_RS05430	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IMX21_RS05435	COG1877	trehalose-phosphatase activity
IMX21_RS05445	COG1129	ABC transporter
IMX21_RS05450	COG1879	ABC-type sugar transport system periplasmic component
IMX21_RS05455	COG1528	Iron-storage protein
IMX21_RS05475	COG1528	Iron-storage protein
IMX21_RS05485	COG0814	amino acid
IMX21_RS05490	COG3012	SEC-C Motif Domain Protein
IMX21_RS05490	COG3318	Belongs to the UPF0149 family
IMX21_RS05495	COG4974	Belongs to the 'phage' integrase family
IMX21_RS05595	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IMX21_RS05640	COG2826	transposase and inactivated derivatives, IS30 family
IMX21_RS05680	COG2197	response regulator
IMX21_RS05695	COG2197	response regulator
IMX21_RS05700	COG1126	abc transporter atp-binding protein
IMX21_RS05705	COG0765	amino acid transport
IMX21_RS05715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX21_RS05725	COG1191	sigma factor activity
IMX21_RS05735	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IMX21_RS05740	COG1516	flagellar protein fliS
IMX21_RS05750	COG0366	Alpha amylase catalytic
IMX21_RS05760	COG2391	methyltransferase activity
IMX21_RS05765	COG0425	Belongs to the sulfur carrier protein TusA family
IMX21_RS05770	COG2135	peptidase activity
IMX21_RS05775	COG0454	-acetyltransferase
IMX21_RS05785	COG0454	-acetyltransferase
IMX21_RS05800	COG1766	The M ring may be actively involved in energy transduction
IMX21_RS05805	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMX21_RS05810	COG1317	bacterial-type flagellum organization
IMX21_RS05815	COG1157	protein secretion by the type III secretion system
IMX21_RS05820	COG2882	bacterial-type flagellum organization
IMX21_RS05825	COG3144	bacterial-type flagellum assembly
IMX21_RS05830	COG1580	Controls the rotational direction of flagella during chemotaxis
IMX21_RS05835	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMX21_RS05840	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMX21_RS05845	COG3190	flagellar
IMX21_RS05850	COG1338	Plays a role in the flagellum-specific transport system
IMX21_RS05855	COG1987	bacterial-type flagellum assembly
IMX21_RS05860	COG1684	flagellar biosynthetic protein fliR
IMX21_RS05865	COG2197	response regulator
IMX21_RS05885	COG3706	GGDEF domain
IMX21_RS05890	COG5475	Uncharacterized small protein (DUF2158)
IMX21_RS05895	COG2354	Protein conserved in bacteria
IMX21_RS05900	COG0697	spore germination
IMX21_RS05905	COG3727	T/G mismatch-specific endonuclease activity
IMX21_RS05910	COG0270	DNA (cytosine-5-)-methyltransferase activity
IMX21_RS05915	COG1418	mRNA catabolic process
IMX21_RS05935	COG2205	protein histidine kinase activity
IMX21_RS05940	COG0745	RESPONSE REGULATOR receiver
IMX21_RS05945	COG2351	hydroxyisourate hydrolase activity
IMX21_RS05960	COG3443	Belongs to the bacterial solute-binding protein 9 family
IMX21_RS05965	COG3038	cytochrome b561
IMX21_RS05985	COG5301	cellulose 1,4-beta-cellobiosidase activity
IMX21_RS06085	COG4372	Transposase
IMX21_RS06090	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS06115	COG3772	lysozyme
IMX21_RS06160	COG2207	Transcriptional regulator
IMX21_RS06180	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IMX21_RS06185	COG1403	HNH endonuclease
IMX21_RS06210	COG1846	Transcriptional regulator
IMX21_RS06215	COG1484	DNA-dependent DNA replication
IMX21_RS06280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX21_RS06295	COG0670	Belongs to the BI1 family
IMX21_RS06300	COG2920	part of a sulfur-relay system
IMX21_RS06305	COG1254	Belongs to the acylphosphatase family
IMX21_RS06320	COG1832	CoA-binding protein
IMX21_RS06335	COG0210	DNA helicase
IMX21_RS06340	COG3304	Inner membrane component domain
IMX21_RS06345	COG1289	transmembrane transporter activity
IMX21_RS06350	COG3070	regulator of competence-specific genes
IMX21_RS06360	COG2885	chlorophyll binding
IMX21_RS06360	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IMX21_RS06370	COG1067	ATP-dependent peptidase activity
IMX21_RS06380	COG3130	regulation of translation
IMX21_RS06385	COG3009	Protein conserved in bacteria
IMX21_RS06390	COG3008	intermembrane lipid transfer
IMX21_RS06390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IMX21_RS06395	COG2995	paraquat-inducible protein a
IMX21_RS06400	COG0488	(ABC) transporter
IMX21_RS06410	COG0633	Ferredoxin
IMX21_RS06410	COG3217	Mosc domain protein beta barrel domain protein
IMX21_RS06430	COG3539	Fimbrial protein
IMX21_RS06435	COG3539	Fimbrial protein
IMX21_RS06440	COG3539	Fimbrial protein
IMX21_RS06450	COG3121	Chaperone
IMX21_RS06455	COG3539	Fimbrial protein
IMX21_RS06460	COG0431	NADPH-dependent FMN reductase
IMX21_RS06465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMX21_RS06475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMX21_RS06480	COG1116	anion transmembrane transporter activity
IMX21_RS06485	COG0308	aminopeptidase N
IMX21_RS06495	COG0017	Asparaginyl-tRNA synthetase
IMX21_RS06505	COG1448	Aminotransferase
IMX21_RS06510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMX21_RS06515	COG3108	Peptidase M15
IMX21_RS06520	COG2989	Protein conserved in bacteria
IMX21_RS06530	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IMX21_RS06540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMX21_RS06545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IMX21_RS06550	COG3173	Aminoglycoside phosphotransferase
IMX21_RS06565	COG3214	Protein conserved in bacteria
IMX21_RS06575	COG1132	(ABC) transporter
IMX21_RS06580	COG2333	competence protein COMEC
IMX21_RS06580	COG0658	competence protein
IMX21_RS06590	COG0539	negative regulation of cytoplasmic translation
IMX21_RS06600	COG0501	Belongs to the peptidase M48B family
IMX21_RS06615	COG2323	membrane
IMX21_RS06620	COG1944	ATP diphosphatase activity
IMX21_RS06625	COG2116	formate transmembrane transporter activity
IMX21_RS06630	COG1882	Formate acetyltransferase
IMX21_RS06635	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMX21_RS06645	COG0531	amino acid
IMX21_RS06655	COG1335	isochorismatase
IMX21_RS06660	COG3302	dmso reductase anchor subunit
IMX21_RS06665	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS06670	COG0243	molybdopterin cofactor binding
IMX21_RS06680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IMX21_RS06690	COG1674	ftsk spoiiie
IMX21_RS06690	COG1178	ABC-type Fe3 transport system permease component
IMX21_RS06695	COG1522	sequence-specific DNA binding
IMX21_RS06700	COG0492	ferredoxin-NADP+ reductase activity
IMX21_RS06705	COG4988	ABC transporter
IMX21_RS06710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IMX21_RS06730	COG0542	response to heat
IMX21_RS06740	COG1278	Cold shock
IMX21_RS06745	COG0577	efflux transmembrane transporter activity
IMX21_RS06745	COG1136	(ABC) transporter
IMX21_RS06750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMX21_RS06755	COG2990	Protein conserved in bacteria
IMX21_RS06760	COG3593	DNA synthesis involved in DNA repair
IMX21_RS06765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IMX21_RS06770	COG2431	L-lysine efflux transmembrane transporter activity
IMX21_RS06780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMX21_RS06785	COG0028	Belongs to the TPP enzyme family
IMX21_RS06790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IMX21_RS06795	COG0702	epimerase
IMX21_RS06800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMX21_RS06805	COG3023	N-Acetylmuramoyl-L-alanine amidase
IMX21_RS06825	COG1126	abc transporter atp-binding protein
IMX21_RS06830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX21_RS06835	COG4215	(ABC) transporter
IMX21_RS06840	COG4160	amino acid transport
IMX21_RS06845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX21_RS06875	COG1177	transmembrane transport
IMX21_RS06880	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMX21_RS06885	COG3842	ATPase activity
IMX21_RS06890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IMX21_RS06905	COG0778	Nitroreductase
IMX21_RS06915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IMX21_RS06930	COG3226	Transcriptional regulator
IMX21_RS06935	COG0738	Major facilitator superfamily
IMX21_RS06940	COG0561	phosphatase activity
IMX21_RS06950	COG2814	Major facilitator Superfamily
IMX21_RS06955	COG0671	phosphoesterase, PA-phosphatase related
IMX21_RS06960	COG1349	DNA-binding transcription factor activity
IMX21_RS06965	COG1686	Belongs to the peptidase S11 family
IMX21_RS06970	COG0625	glutathione transferase activity
IMX21_RS06975	COG2133	pyrroloquinoline quinone binding
IMX21_RS07000	COG2199	diguanylate cyclase activity
IMX21_RS07005	COG2200	EAL domain
IMX21_RS07015	COG0601	transmembrane transport
IMX21_RS07020	COG0747	negative chemotaxis
IMX21_RS07025	COG4172	Belongs to the ABC transporter superfamily
IMX21_RS07035	COG0303	'Molybdopterin
IMX21_RS07040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMX21_RS07045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMX21_RS07050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMX21_RS07060	COG0561	phosphatase activity
IMX21_RS07070	COG0488	(ABC) transporter
IMX21_RS07075	COG1376	ErfK ybiS ycfS ynhG family protein
IMX21_RS07080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IMX21_RS07085	COG1321	iron dependent repressor
IMX21_RS07095	COG2194	sulfuric ester hydrolase activity
IMX21_RS07100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IMX21_RS07110	COG5006	permease, DMT superfamily
IMX21_RS07120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX21_RS07125	COG0765	amino acid transport
IMX21_RS07130	COG1126	abc transporter atp-binding protein
IMX21_RS07135	COG0668	transmembrane transport
IMX21_RS07150	COG4774	siderophore transport
IMX21_RS07160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IMX21_RS07170	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IMX21_RS07175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMX21_RS07180	COG1199	ATP-dependent helicase activity
IMX21_RS07190	COG0513	Belongs to the DEAD box helicase family
IMX21_RS07195	COG1309	transcriptional regulator
IMX21_RS07205	COG1131	(ABC) transporter
IMX21_RS07210	COG0842	Transport permease protein
IMX21_RS07215	COG0842	Transport permease protein
IMX21_RS07225	COG3568	Endonuclease Exonuclease Phosphatase
IMX21_RS07230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMX21_RS07235	COG0392	lysyltransferase activity
IMX21_RS07240	COG0670	Belongs to the BI1 family
IMX21_RS07245	COG0670	Belongs to the BI1 family
IMX21_RS07250	COG0314	molybdopterin synthase activity
IMX21_RS07255	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IMX21_RS07265	COG0521	Mo-molybdopterin cofactor biosynthetic process
IMX21_RS07275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IMX21_RS07285	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IMX21_RS07290	COG2226	methyltransferase
IMX21_RS07305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMX21_RS07310	COG1881	PFAM PEBP family protein
IMX21_RS07350	COG5301	cellulose 1,4-beta-cellobiosidase activity
IMX21_RS07425	COG0740	serine-type endopeptidase activity
IMX21_RS07465	COG3772	lysozyme
IMX21_RS07575	COG0582	viral genome integration into host DNA
IMX21_RS07580	COG4677	pectinesterase activity
IMX21_RS07585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMX21_RS07590	COG0471	metal ion transport
IMX21_RS07595	COG2828	Protein conserved in bacteria
IMX21_RS07600	COG0583	DNA-binding transcription factor activity
IMX21_RS07610	COG0561	phosphatase activity
IMX21_RS07620	COG4149	molybdate abc transporter
IMX21_RS07625	COG0725	ABC transporter, periplasmic molybdate-binding protein
IMX21_RS07635	COG3585	molybdate ion transport
IMX21_RS07635	COG2005	Transcriptional regulator
IMX21_RS07640	COG1119	ATPase activity
IMX21_RS07645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMX21_RS07650	COG1085	galactose-1-phosphate uridylyltransferase
IMX21_RS07660	COG2017	converts alpha-aldose to the beta-anomer
IMX21_RS07670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMX21_RS07680	COG1230	cation diffusion facilitator family transporter
IMX21_RS07685	COG3201	nicotinamide mononucleotide transporter
IMX21_RS07690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IMX21_RS07725	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IMX21_RS07730	COG2885	chlorophyll binding
IMX21_RS07740	COG3064	Membrane
IMX21_RS07745	COG0848	biopolymer transport protein
IMX21_RS07750	COG0811	peptide transport
IMX21_RS07755	COG0824	Thioesterase
IMX21_RS07760	COG3790	cyd operon protein YbgE
IMX21_RS07765	COG4890	Cyd operon protein YbgT
IMX21_RS07770	COG1294	oxidase, subunit
IMX21_RS07775	COG1271	oxidase subunit
IMX21_RS07790	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMX21_RS07800	COG4865	methylaspartate mutase activity
IMX21_RS07805	COG3799	methylaspartate ammonia-lyase activity
IMX21_RS07820	COG1301	dicarboxylic acid transport
IMX21_RS07825	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IMX21_RS07825	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IMX21_RS07830	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IMX21_RS07835	COG0583	DNA-binding transcription factor activity
IMX21_RS07840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMX21_RS07850	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMX21_RS07855	COG0567	Dehydrogenase, E1 component
IMX21_RS07860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IMX21_RS07865	COG1053	succinate dehydrogenase
IMX21_RS07870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IMX21_RS07875	COG2009	succinate dehydrogenase
IMX21_RS07885	COG0372	Belongs to the citrate synthase family
IMX21_RS07890	COG3539	Fimbrial protein
IMX21_RS07900	COG3121	Chaperone
IMX21_RS07905	COG3539	Fimbrial protein
IMX21_RS07910	COG3180	Ammonia monooxygenase
IMX21_RS07915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IMX21_RS07925	COG1984	allophanate hydrolase subunit 2
IMX21_RS07930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IMX21_RS07935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMX21_RS07940	COG3104	oligopeptide transport
IMX21_RS07945	COG0415	Belongs to the DNA photolyase family
IMX21_RS07950	COG3272	Protein of unknown function (DUF1722)
IMX21_RS07970	COG3209	COG3209 Rhs family protein
IMX21_RS08000	COG2205	protein histidine kinase activity
IMX21_RS08005	COG0745	RESPONSE REGULATOR receiver
IMX21_RS08015	COG1982	Orn Lys Arg decarboxylase major
IMX21_RS08020	COG0531	amino acid
IMX21_RS08025	COG0033	Phosphoglucomutase
IMX21_RS08030	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IMX21_RS08035	COG0596	Alpha beta hydrolase
IMX21_RS08045	COG0716	FMN binding
IMX21_RS08055	COG0735	belongs to the Fur family
IMX21_RS08075	COG2190	(PTS) system
IMX21_RS08075	COG1263	PTS System
IMX21_RS08075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX21_RS08085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMX21_RS08090	COG1846	Transcriptional regulator
IMX21_RS08090	COG1940	carbohydrate kinase activity
IMX21_RS08095	COG0647	UMP catabolic process
IMX21_RS08100	COG0367	asparagine synthase
IMX21_RS08140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMX21_RS08150	COG1702	phosphate starvation-inducible protein PhoH
IMX21_RS08160	COG4535	Mg2 and Co2 transporter CorC
IMX21_RS08165	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IMX21_RS08170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX21_RS08175	COG0765	amino acid transport
IMX21_RS08180	COG0765	amino acid transport
IMX21_RS08185	COG1126	abc transporter atp-binding protein
IMX21_RS08195	COG0443	Heat shock 70 kDa protein
IMX21_RS08210	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IMX21_RS08215	COG2214	Heat shock protein DnaJ domain protein
IMX21_RS08230	COG2888	peptidyl-tyrosine sulfation
IMX21_RS08245	COG1466	dna polymerase III delta subunit
IMX21_RS08255	COG0406	alpha-ribazole phosphatase activity
IMX21_RS08260	COG0799	negative regulation of ribosome biogenesis
IMX21_RS08270	COG0768	penicillin binding
IMX21_RS08275	COG0772	Belongs to the SEDS family
IMX21_RS08280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IMX21_RS08285	COG1686	Belongs to the peptidase S11 family
IMX21_RS08300	COG0583	DNA-binding transcription factor activity
IMX21_RS08310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMX21_RS08315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMX21_RS08335	COG3069	C4-dicarboxylate transmembrane transporter activity
IMX21_RS08340	COG4565	transcriptional regulatory protein
IMX21_RS08345	COG3290	protein histidine kinase activity
IMX21_RS08350	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IMX21_RS08360	COG2301	Belongs to the HpcH HpaI aldolase family
IMX21_RS08365	COG3051	citrate lyase alpha subunit
IMX21_RS08375	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IMX21_RS08380	COG0471	metal ion transport
IMX21_RS08385	COG3719	Belongs to the RNase T2 family
IMX21_RS08390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMX21_RS08395	COG1063	alcohol dehydrogenase
IMX21_RS08400	COG0589	response to stress
IMX21_RS08405	COG3634	alkyl hydroperoxide reductase activity
IMX21_RS08410	COG0450	alkyl hydroperoxide reductase
IMX21_RS08415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IMX21_RS08420	COG0583	DNA-binding transcription factor activity
IMX21_RS08425	COG3969	phosphoadenosine phosphosulfate
IMX21_RS08430	COG1475	DNA binding
IMX21_RS08435	COG0436	Aminotransferase
IMX21_RS08440	COG0371	Dehydrogenase
IMX21_RS08445	COG2879	small protein
IMX21_RS08450	COG1966	Carbon starvation protein
IMX21_RS08460	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS08465	COG1535	isochorismatase
IMX21_RS08465	COG3433	isochorismatase activity
IMX21_RS08470	COG1021	2,3-dihydroxybenzoate-AMP ligase
IMX21_RS08475	COG1169	isochorismate synthase
IMX21_RS08480	COG4592	Periplasmic binding protein
IMX21_RS08490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMX21_RS08495	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMX21_RS08500	COG1120	ATPase activity
IMX21_RS08505	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IMX21_RS08510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMX21_RS08510	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IMX21_RS08515	COG3251	PFAM MbtH domain protein
IMX21_RS08520	COG2382	esterase
IMX21_RS08525	COG4771	TonB-dependent receptor
IMX21_RS08530	COG2977	Belongs to the P-Pant transferase superfamily
IMX21_RS08555	COG2315	Protein conserved in bacteria
IMX21_RS08560	COG0778	Nitroreductase
IMX21_RS08565	COG0668	transmembrane transport
IMX21_RS08570	COG1113	amino acid transport
IMX21_RS08575	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMX21_RS08580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMX21_RS08585	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMX21_RS08590	COG1538	Outer membrane efflux protein
IMX21_RS08595	COG0745	RESPONSE REGULATOR receiver
IMX21_RS08600	COG5002	protein histidine kinase activity
IMX21_RS08615	COG4104	PAAR repeat-containing protein
IMX21_RS08615	COG3209	COG3209 Rhs family protein
IMX21_RS08625	COG4104	PAAR repeat-containing protein
IMX21_RS08625	COG3209	COG3209 Rhs family protein
IMX21_RS08635	COG5433	transposase activity
IMX21_RS08640	COG1215	transferase activity, transferring glycosyl groups
IMX21_RS08645	COG4783	chaperone-mediated protein folding
IMX21_RS08655	COG2207	Transcriptional regulator
IMX21_RS08665	COG2197	response regulator
IMX21_RS08670	COG3539	Fimbrial protein
IMX21_RS08675	COG3539	Fimbrial protein
IMX21_RS08680	COG3188	usher protein
IMX21_RS08685	COG3121	Chaperone
IMX21_RS08690	COG3539	Fimbrial protein
IMX21_RS08700	COG2501	S4 domain
IMX21_RS08705	COG1988	membrane-bound metal-dependent
IMX21_RS08715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMX21_RS08725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMX21_RS08730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMX21_RS08735	COG0549	Belongs to the carbamate kinase family
IMX21_RS08745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMX21_RS08750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMX21_RS08755	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IMX21_RS08760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMX21_RS08765	COG3257	ureidoglycine aminohydrolase activity
IMX21_RS08770	COG1929	Belongs to the glycerate kinase type-1 family
IMX21_RS08775	COG2233	PERMEase
IMX21_RS08785	COG1953	Uracil, thiamine, allantoin
IMX21_RS08790	COG2084	Dehydrogenase
IMX21_RS08795	COG3622	Belongs to the hyi family
IMX21_RS08800	COG3960	tartronate-semialdehyde synthase activity
IMX21_RS08805	COG1414	Transcriptional regulator
IMX21_RS08815	COG0583	DNA-binding transcription factor activity
IMX21_RS08835	COG3209	COG3209 Rhs family protein
IMX21_RS08840	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IMX21_RS08845	COG4181	ATPase activity
IMX21_RS08850	COG2755	lipolytic protein G-D-S-L family
IMX21_RS08855	COG0300	oxidoreductase activity
IMX21_RS08860	COG3118	belongs to the thioredoxin family
IMX21_RS08865	COG0390	transport system, permease component
IMX21_RS08870	COG4619	ABC transporter
IMX21_RS08875	COG0330	HflC and HflK could
IMX21_RS08880	COG1585	Membrane protein implicated in regulation of membrane protease activity
IMX21_RS08900	COG0789	Transcriptional regulator
IMX21_RS08925	COG0531	amino acid
IMX21_RS08930	COG2066	Belongs to the glutaminase family
IMX21_RS08935	COG2217	Heavy metal translocating P-type atpase
IMX21_RS08940	COG3093	addiction module antidote protein HigA
IMX21_RS08945	COG3735	TraB family
IMX21_RS08950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMX21_RS08955	COG0737	Belongs to the 5'-nucleotidase family
IMX21_RS08960	COG2223	nitrite transmembrane transporter activity
IMX21_RS08965	COG4651	solute:proton antiporter activity
IMX21_RS08965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IMX21_RS08970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX21_RS09005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMX21_RS09015	COG2832	Protein of unknown function (DUF454)
IMX21_RS09020	COG3923	Primosomal replication protein n
IMX21_RS09030	COG1196	nuclear chromosome segregation
IMX21_RS09030	COG3264	Mechanosensitive ion channel
IMX21_RS09035	COG1309	transcriptional regulator
IMX21_RS09040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMX21_RS09045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMX21_RS09060	COG0110	maltose O-acetyltransferase activity
IMX21_RS09070	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IMX21_RS09075	COG5507	3-demethylubiquinone-9 3-methyltransferase
IMX21_RS09085	COG3695	enzyme binding
IMX21_RS09090	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IMX21_RS09095	COG1946	Acyl-CoA thioesterase
IMX21_RS09100	COG0004	ammonium transporteR
IMX21_RS09105	COG0347	Belongs to the P(II) protein family
IMX21_RS09110	COG1132	(ABC) transporter
IMX21_RS09115	COG1132	(ABC) transporter
IMX21_RS09120	COG1522	sequence-specific DNA binding
IMX21_RS09130	COG4533	DNA binding
IMX21_RS09140	COG0824	Thioesterase
IMX21_RS09145	COG1555	photosystem II stabilization
IMX21_RS09150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMX21_RS09155	COG0776	regulation of translation
IMX21_RS09160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IMX21_RS09180	COG0271	Belongs to the BolA IbaG family
IMX21_RS09185	COG3056	Lipoprotein
IMX21_RS09190	COG2223	nitrite transmembrane transporter activity
IMX21_RS09195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMX21_RS09200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMX21_RS09205	COG1845	cytochrome c oxidase, subunit III
IMX21_RS09210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IMX21_RS09220	COG2814	Major facilitator Superfamily
IMX21_RS09230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMX21_RS09235	COG0693	protein deglycase activity
IMX21_RS09250	COG0142	geranyltranstransferase activity
IMX21_RS09260	COG0667	Aldo Keto reductase
IMX21_RS09270	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IMX21_RS09275	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IMX21_RS09290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMX21_RS09290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMX21_RS09300	COG4238	major outer membrane lipoprotein
IMX21_RS09305	COG3248	Nucleoside-binding outer membrane protein
IMX21_RS09310	COG1403	HNH endonuclease
IMX21_RS09320	COG3609	addiction module antidote protein, CC2985 family
IMX21_RS09325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMX21_RS09330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMX21_RS09335	COG1862	Preprotein translocase
IMX21_RS09360	COG0366	Alpha amylase catalytic
IMX21_RS09365	COG1113	amino acid transport
IMX21_RS09370	COG1114	Component of the transport system for branched-chain amino acids
IMX21_RS09375	COG5002	protein histidine kinase activity
IMX21_RS09380	COG0745	RESPONSE REGULATOR receiver
IMX21_RS09385	COG0420	3'-5' exonuclease activity
IMX21_RS09390	COG0419	ATPase involved in DNA repair
IMX21_RS09395	COG2814	Major facilitator Superfamily
IMX21_RS09400	COG1940	carbohydrate kinase activity
IMX21_RS09425	COG4126	flavin adenine dinucleotide binding
IMX21_RS09445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMX21_RS09450	COG3706	GGDEF domain
IMX21_RS09460	COG1785	Belongs to the alkaline phosphatase family
IMX21_RS09475	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMX21_RS09495	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IMX21_RS09500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IMX21_RS09505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMX21_RS09510	COG3468	outer membrane autotransporter barrel domain protein
IMX21_RS09515	COG0113	porphobilinogen synthase activity
IMX21_RS09520	COG2175	clavaminate synthase activity
IMX21_RS09525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMX21_RS09530	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IMX21_RS09535	COG4521	taurine ABC transporter
IMX21_RS09550	COG2271	Major facilitator Superfamily
IMX21_RS09555	COG1840	ABC-type Fe3 transport system, periplasmic component
IMX21_RS09565	COG3842	ATPase activity
IMX21_RS09580	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IMX21_RS09585	COG3122	Protein conserved in bacteria
IMX21_RS09590	COG2814	Major facilitator Superfamily
IMX21_RS09595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMX21_RS09610	COG0596	Alpha beta hydrolase
IMX21_RS09625	COG1414	Transcriptional regulator
IMX21_RS09630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IMX21_RS09640	COG1609	Transcriptional regulator
IMX21_RS09645	COG3250	beta-galactosidase activity
IMX21_RS09650	COG2223	nitrite transmembrane transporter activity
IMX21_RS09655	COG0110	maltose O-acetyltransferase activity
IMX21_RS09660	COG2807	transmembrane transport
IMX21_RS09670	COG0288	reversible hydration of carbon dioxide
IMX21_RS09675	COG0583	DNA-binding transcription factor activity
IMX21_RS09680	COG0402	S-adenosylhomocysteine deaminase activity
IMX21_RS09685	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IMX21_RS09690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMX21_RS09695	COG2079	MmgE PrpD family protein
IMX21_RS09700	COG0372	Belongs to the citrate synthase family
IMX21_RS09705	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IMX21_RS09710	COG3829	transcription factor binding
IMX21_RS09720	COG1280	lysine exporter protein (LysE YggA)
IMX21_RS09735	COG1064	alcohol dehydrogenase
IMX21_RS09745	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS09755	COG1879	ABC-type sugar transport system periplasmic component
IMX21_RS09765	COG0402	S-adenosylhomocysteine deaminase activity
IMX21_RS09770	COG0549	Belongs to the carbamate kinase family
IMX21_RS09780	COG1304	FMN binding
IMX21_RS09785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMX21_RS09795	COG0666	response to abiotic stimulus
IMX21_RS09810	COG2771	luxR family
IMX21_RS09810	COG2200	EAL domain
IMX21_RS09820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IMX21_RS09875	COG1556	Lactate utilization protein
IMX21_RS09880	COG1139	Iron-sulfur cluster binding protein
IMX21_RS09885	COG0247	lactate metabolic process
IMX21_RS09890	COG2207	Transcriptional regulator
IMX21_RS09895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMX21_RS09905	COG3059	membrane
IMX21_RS09910	COG0656	L-ascorbic acid biosynthetic process
IMX21_RS09915	COG3708	Transcriptional regulator
IMX21_RS09915	COG2207	Transcriptional regulator
IMX21_RS09920	COG1388	LysM domain
IMX21_RS09935	COG0583	DNA-binding transcription factor activity
IMX21_RS09940	COG1073	alpha beta
IMX21_RS09945	COG1902	pentaerythritol trinitrate reductase activity
IMX21_RS09955	COG4372	Transposase
IMX21_RS09960	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS10000	COG3188	usher protein
IMX21_RS10010	COG3121	Chaperone
IMX21_RS10015	COG0727	PFAM Uncharacterised protein family (UPF0153)
IMX21_RS10020	COG3477	response to acidic pH
IMX21_RS10025	COG2080	2 iron, 2 sulfur cluster binding
IMX21_RS10030	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IMX21_RS10035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IMX21_RS10040	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IMX21_RS10055	COG0583	DNA-binding transcription factor activity
IMX21_RS10065	COG4221	oxidoreductase activity
IMX21_RS10070	COG0583	DNA-binding transcription factor activity
IMX21_RS10150	COG0582	viral genome integration into host DNA
IMX21_RS10170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IMX21_RS10180	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IMX21_RS10250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IMX21_RS10270	COG2195	Cleaves the N-terminal amino acid of tripeptides
IMX21_RS10285	COG0454	-acetyltransferase
IMX21_RS10295	COG2161	toxin-antitoxin pair type II binding
IMX21_RS10300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMX21_RS10320	COG0791	NLP P60 protein
IMX21_RS10325	COG3077	Addiction module antitoxin, RelB DinJ family
IMX21_RS10330	COG3041	Addiction module toxin RelE StbE family
IMX21_RS10335	COG3034	peptidoglycan biosynthetic process
IMX21_RS10340	COG0121	glutamine amidotransferase
IMX21_RS10350	COG1960	acyl-CoA dehydrogenase activity
IMX21_RS10360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMX21_RS10365	COG5433	transposase activity
IMX21_RS10385	COG5433	transposase activity
IMX21_RS10395	COG3209	COG3209 Rhs family protein
IMX21_RS10515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX21_RS10525	COG2226	methyltransferase
IMX21_RS10535	COG1388	LysM domain
IMX21_RS10535	COG0741	lytic transglycosylase activity
IMX21_RS10540	COG2226	methyltransferase
IMX21_RS10550	COG0583	DNA-binding transcription factor activity
IMX21_RS10555	COG0656	L-ascorbic acid biosynthetic process
IMX21_RS10590	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IMX21_RS10595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMX21_RS10600	COG2011	ABC-type metal ion transport system permease component
IMX21_RS10605	COG1464	Belongs to the NlpA lipoprotein family
IMX21_RS10615	COG1720	tRNA m6t6A37 methyltransferase activity
IMX21_RS10625	COG0791	NLP P60 protein
IMX21_RS10630	COG3015	lipoprotein NlpE involved in copper resistance
IMX21_RS10635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IMX21_RS10650	COG4568	rho-dependent transcription termination
IMX21_RS10655	COG0037	tRNA processing
IMX21_RS10660	COG0346	lactoylglutathione lyase activity
IMX21_RS10665	COG1982	Orn Lys Arg decarboxylase major
IMX21_RS10675	COG0587	DNA-directed DNA polymerase activity
IMX21_RS10700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IMX21_RS10705	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IMX21_RS10715	COG0750	zinc metalloprotease
IMX21_RS10720	COG0575	Belongs to the CDS family
IMX21_RS10725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMX21_RS10730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IMX21_RS10755	COG0024	Methionine aminopeptidase
IMX21_RS10775	COG3835	regulator
IMX21_RS10780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMX21_RS10795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMX21_RS10800	COG2860	membrane
IMX21_RS10825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMX21_RS10830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMX21_RS10835	COG1120	ATPase activity
IMX21_RS10840	COG4774	siderophore transport
IMX21_RS10845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMX21_RS10850	COG1643	Atp-dependent helicase
IMX21_RS10855	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IMX21_RS10865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IMX21_RS10870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMX21_RS10875	COG0617	tRNA 3'-terminal CCA addition
IMX21_RS10880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMX21_RS10890	COG3121	Chaperone
IMX21_RS10895	COG3188	usher protein
IMX21_RS10900	COG3539	Fimbrial protein
IMX21_RS10905	COG3539	Fimbrial protein
IMX21_RS10930	COG5464	transposase or invertase
IMX21_RS10940	COG0726	polysaccharide deacetylase
IMX21_RS10945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS10950	COG0842	Transport permease protein
IMX21_RS10955	COG1131	(ABC) transporter
IMX21_RS10960	COG0288	reversible hydration of carbon dioxide
IMX21_RS10965	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IMX21_RS10970	COG4993	Dehydrogenase
IMX21_RS10975	COG2132	Multicopper oxidase
IMX21_RS11000	COG1049	propionate catabolic process, 2-methylcitrate cycle
IMX21_RS11005	COG3064	Membrane
IMX21_RS11010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMX21_RS11015	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMX21_RS11020	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IMX21_RS11025	COG2186	Transcriptional regulator
IMX21_RS11030	COG1113	amino acid transport
IMX21_RS11035	COG3725	Membrane protein required for beta-lactamase induction
IMX21_RS11040	COG3023	N-Acetylmuramoyl-L-alanine amidase
IMX21_RS11045	COG0157	Belongs to the NadC ModD family
IMX21_RS11050	COG4969	Belongs to the N-Me-Phe pilin family
IMX21_RS11055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMX21_RS11060	COG1459	type II secretion system
IMX21_RS11075	COG0237	dephospho-CoA kinase activity
IMX21_RS11090	COG0494	nUDIX hydrolase
IMX21_RS11110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMX21_RS11115	COG0849	cell division
IMX21_RS11120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IMX21_RS11125	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMX21_RS11140	COG0772	Belongs to the SEDS family
IMX21_RS11145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMX21_RS11155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMX21_RS11160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMX21_RS11165	COG0768	penicillin binding
IMX21_RS11170	COG3116	cell division
IMX21_RS11185	COG1609	Transcriptional regulator
IMX21_RS11195	COG0440	acetolactate synthase activity
IMX21_RS11200	COG0028	Belongs to the TPP enzyme family
IMX21_RS11205	COG0583	DNA-binding transcription factor activity
IMX21_RS11220	COG0473	3-isopropylmalate dehydrogenase activity
IMX21_RS11240	COG4533	DNA binding
IMX21_RS11250	COG4143	(ABC) transporter
IMX21_RS11255	COG1178	ABC-type Fe3 transport system permease component
IMX21_RS11260	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IMX21_RS11265	COG0586	Pfam SNARE associated Golgi protein
IMX21_RS11270	COG4977	sequence-specific DNA binding
IMX21_RS11285	COG0235	Class ii aldolase
IMX21_RS11290	COG0417	DNA replication proofreading
IMX21_RS11300	COG0564	pseudouridine synthase activity
IMX21_RS11310	COG1357	PFAM Pentapeptide repeats (8 copies)
IMX21_RS11315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IMX21_RS11320	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IMX21_RS11325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMX21_RS11360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMX21_RS11375	COG2271	Major facilitator Superfamily
IMX21_RS11380	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IMX21_RS11385	COG0644	oxidoreductase
IMX21_RS11420	COG1024	Enoyl-CoA hydratase
IMX21_RS11435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMX21_RS11440	COG0505	Belongs to the CarA family
IMX21_RS11460	COG1047	Peptidyl-prolyl cis-trans
IMX21_RS11475	COG0196	riboflavin kinase activity
IMX21_RS11500	COG3121	Chaperone
IMX21_RS11505	COG3188	usher protein
IMX21_RS11515	COG0583	DNA-binding transcription factor activity
IMX21_RS11545	COG4735	regulation of single-species biofilm formation
IMX21_RS11550	COG1584	GPR1 FUN34 yaaH family protein
IMX21_RS11555	COG0521	Mo-molybdopterin cofactor biosynthetic process
IMX21_RS11560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMX21_RS11565	COG1115	amino acid carrier protein
IMX21_RS11580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMX21_RS11590	COG0527	aspartate kinase activity
IMX21_RS11590	COG0460	homoserine dehydrogenase
IMX21_RS11600	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IMX21_RS11610	COG0745	RESPONSE REGULATOR receiver
IMX21_RS11615	COG4452	Inner membrane protein CreD
IMX21_RS11620	COG2205	protein histidine kinase activity
IMX21_RS11625	COG0745	RESPONSE REGULATOR receiver
IMX21_RS11630	COG3045	CreA protein
IMX21_RS11635	COG3708	Transcriptional regulator
IMX21_RS11635	COG2207	Transcriptional regulator
IMX21_RS11645	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IMX21_RS11655	COG0741	lytic transglycosylase activity
IMX21_RS11660	COG0488	(ABC) transporter
IMX21_RS11670	COG3172	ATPase kinase involved in NAD metabolism
IMX21_RS11670	COG1056	cytidyltransferase-related domain
IMX21_RS11675	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMX21_RS11680	COG0560	Phosphoserine phosphatase
IMX21_RS11690	COG3726	membrane protein affecting hemolysin expression
IMX21_RS11690	COG0095	Lipoate-protein ligase
IMX21_RS11725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMX21_RS11730	COG0084	hydrolase, TatD family'
IMX21_RS11735	COG4667	esterase of the alpha-beta hydrolase superfamily
IMX21_RS11745	COG2823	Periplasmic or secreted lipoprotein
IMX21_RS11755	COG1011	Hydrolase
IMX21_RS11760	COG0456	acetyltransferase
IMX21_RS11765	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IMX21_RS11785	COG4114	ferric iron reductase
IMX21_RS11790	COG2197	response regulator
IMX21_RS11795	COG2197	response regulator
IMX21_RS11800	COG2966	Psort location CytoplasmicMembrane, score
IMX21_RS11815	COG1484	DNA-dependent DNA replication
IMX21_RS11830	COG1063	alcohol dehydrogenase
IMX21_RS11835	COG1802	Transcriptional regulator
IMX21_RS11840	COG2271	Major facilitator Superfamily
IMX21_RS11845	COG0840	transmembrane signaling receptor activity
IMX21_RS11855	COG1966	Carbon starvation protein
IMX21_RS11860	COG2879	small protein
IMX21_RS11865	COG0523	cobalamin synthesis protein
IMX21_RS11890	COG0732	type I restriction modification DNA specificity domain
IMX21_RS11910	COG5457	Domain of unknown function (DUF1127)
IMX21_RS11915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMX21_RS11930	COG2814	Major facilitator Superfamily
IMX21_RS11935	COG2733	membrane
IMX21_RS11940	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
IMX21_RS11945	COG1924	4 iron, 4 sulfur cluster binding
IMX21_RS11960	COG3204	pilus organization
IMX21_RS11965	COG0477	Major facilitator Superfamily
IMX21_RS11980	COG3366	ferrous iron transmembrane transporter activity
IMX21_RS11985	COG0700	Nucleoside recognition
IMX21_RS11990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMX21_RS12015	COG2186	Transcriptional regulator
IMX21_RS12020	COG0246	Mannitol dehydrogenase
IMX21_RS12030	COG2610	gluconate transmembrane transporter activity
IMX21_RS12035	COG3539	Fimbrial protein
IMX21_RS12040	COG3539	Fimbrial protein
IMX21_RS12045	COG3539	Fimbrial protein
IMX21_RS12050	COG3188	usher protein
IMX21_RS12055	COG3121	Chaperone
IMX21_RS12060	COG3539	Fimbrial protein
IMX21_RS12065	COG3539	Fimbrial protein
IMX21_RS12070	COG4974	Belongs to the 'phage' integrase family
IMX21_RS12075	COG0582	viral genome integration into host DNA
IMX21_RS12080	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IMX21_RS12085	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IMX21_RS12100	COG0210	DNA helicase
IMX21_RS12105	COG1205	dead DEAH box helicase
IMX21_RS12105	COG1111	helicase
IMX21_RS12115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMX21_RS12160	COG0582	viral genome integration into host DNA
IMX21_RS12215	COG1064	alcohol dehydrogenase
IMX21_RS12220	COG0433	COG0433 Predicted ATPase
IMX21_RS12225	COG0795	lipopolysaccharide-transporting ATPase activity
IMX21_RS12230	COG0795	lipopolysaccharide-transporting ATPase activity
IMX21_RS12240	COG2927	DNA polymerase III (CHI subunit)
IMX21_RS12250	COG4269	membrane
IMX21_RS12255	COG0456	acetyltransferase
IMX21_RS12260	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IMX21_RS12265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMX21_RS12275	COG2731	YhcH YjgK YiaL family protein
IMX21_RS12280	COG1309	transcriptional regulator
IMX21_RS12285	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS12290	COG0251	oxidation-reduction process
IMX21_RS12310	COG0251	oxidation-reduction process
IMX21_RS12315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMX21_RS12325	COG1609	Transcriptional regulator
IMX21_RS12330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX21_RS12330	COG1263	PTS System
IMX21_RS12335	COG0366	Alpha amylase catalytic
IMX21_RS12340	COG1328	CTP reductase activity
IMX21_RS12345	COG0602	queuosine metabolic process
IMX21_RS12350	COG3783	Cytochrome b(562)
IMX21_RS12355	COG0312	modulator of DNA gyrase
IMX21_RS12365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMX21_RS12375	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS12380	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS12385	COG1129	ABC transporter
IMX21_RS12390	COG1879	ABC-type sugar transport system periplasmic component
IMX21_RS12395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IMX21_RS12400	COG2337	Toxic component of a toxin-antitoxin (TA) module
IMX21_RS12405	COG2336	PFAM SpoVT AbrB
IMX21_RS12410	COG2105	PFAM AIG2 family protein
IMX21_RS12415	COG2911	Protein conserved in bacteria
IMX21_RS12420	COG0729	surface antigen
IMX21_RS12430	COG1253	flavin adenine dinucleotide binding
IMX21_RS12440	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IMX21_RS12450	COG1218	3'(2'),5'-bisphosphate nucleotidase
IMX21_RS12455	COG0737	Belongs to the 5'-nucleotidase family
IMX21_RS12460	COG1733	regulation of RNA biosynthetic process
IMX21_RS12465	COG0702	epimerase
IMX21_RS12470	COG0697	spore germination
IMX21_RS12480	COG1113	amino acid transport
IMX21_RS12485	COG0545	Peptidyl-prolyl cis-trans isomerase
IMX21_RS12490	COG3061	Opacity-associated protein A
IMX21_RS12500	COG0675	Transposase, IS605 OrfB family
IMX21_RS12525	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMX21_RS12560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS12565	COG3414	Phosphotransferase system galactitol-specific IIB component
IMX21_RS12570	COG3037	sugar-specific permease SgaT UlaA
IMX21_RS12585	COG1073	alpha beta
IMX21_RS12590	COG3650	response to hydrogen peroxide
IMX21_RS12600	COG1960	acyl-CoA dehydrogenase activity
IMX21_RS12605	COG0754	glutathionylspermidine amidase activity
IMX21_RS12610	COG5463	Belongs to the UPF0441 family
IMX21_RS12615	COG3766	membrane
IMX21_RS12625	COG1842	Phage shock protein A
IMX21_RS12630	COG3789	protein conserved in bacteria
IMX21_RS12635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMX21_RS12640	COG0557	exoribonuclease II activity
IMX21_RS12655	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IMX21_RS12660	COG0330	HflC and HflK could
IMX21_RS12665	COG0330	HflC and HflK could
IMX21_RS12670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMX21_RS12685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMX21_RS12690	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMX21_RS12695	COG0802	atpase or kinase
IMX21_RS12700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMX21_RS12700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMX21_RS12730	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IMX21_RS12745	COG1511	domain protein
IMX21_RS12745	COG3264	Mechanosensitive ion channel
IMX21_RS12750	COG0531	amino acid
IMX21_RS12760	COG1053	succinate dehydrogenase
IMX21_RS12765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IMX21_RS12780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IMX21_RS12785	COG3040	lipid binding
IMX21_RS12790	COG2076	Multidrug Resistance protein
IMX21_RS12795	COG5510	response to toxic substance
IMX21_RS12800	COG5510	response to toxic substance
IMX21_RS12810	COG1509	lysine 2,3-aminomutase activity
IMX21_RS12835	COG0531	amino acid
IMX21_RS12840	COG3030	protein affecting phage T7 exclusion by the F plasmid
IMX21_RS12845	COG1027	Aspartate ammonia-lyase
IMX21_RS12850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IMX21_RS12860	COG4232	protein-disulfide reductase activity
IMX21_RS12865	COG1309	transcriptional regulator
IMX21_RS12875	COG3710	Transcriptional regulator
IMX21_RS12880	COG0531	amino acid
IMX21_RS12885	COG1982	Orn Lys Arg decarboxylase major
IMX21_RS12890	COG3104	oligopeptide transport
IMX21_RS12895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMX21_RS12910	COG2388	GCN5-related N-acetyl-transferase
IMX21_RS12915	COG3592	Divergent 4Fe-4S mono-cluster
IMX21_RS12920	COG3290	protein histidine kinase activity
IMX21_RS12925	COG4565	transcriptional regulatory protein
IMX21_RS12930	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IMX21_RS12935	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IMX21_RS12935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IMX21_RS12940	COG3647	Membrane
IMX21_RS12945	COG2211	Major facilitator Superfamily
IMX21_RS12950	COG1486	melibiose metabolic process
IMX21_RS12955	COG2169	Transcriptional regulator
IMX21_RS12960	COG1982	Orn Lys Arg decarboxylase major
IMX21_RS12965	COG2207	Transcriptional regulator
IMX21_RS12970	COG0531	amino acid
IMX21_RS12975	COG2194	sulfuric ester hydrolase activity
IMX21_RS12980	COG0745	RESPONSE REGULATOR receiver
IMX21_RS12985	COG0642	Histidine kinase
IMX21_RS12995	COG0477	Major facilitator Superfamily
IMX21_RS13005	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IMX21_RS13010	COG2824	Alkylphosphonate utilization operon protein PhnA
IMX21_RS13015	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IMX21_RS13020	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IMX21_RS13025	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IMX21_RS13030	COG3639	organic phosphonate transmembrane transporter activity
IMX21_RS13035	COG2188	Transcriptional regulator
IMX21_RS13040	COG3624	Phosphonate C-P lyase system protein PhnG
IMX21_RS13045	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IMX21_RS13050	COG3626	phosphonate metabolism
IMX21_RS13055	COG3627	carbon phosphorus lyase activity
IMX21_RS13060	COG4107	phosphonate C-P lyase system protein PhnK
IMX21_RS13065	COG4778	phosphonate C-P lyase system protein PhnL
IMX21_RS13070	COG3454	Phosphonate metabolism
IMX21_RS13075	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IMX21_RS13080	COG0456	acetyltransferase
IMX21_RS13085	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IMX21_RS13100	COG1129	ABC transporter
IMX21_RS13105	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS13125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX21_RS13135	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IMX21_RS13145	COG1566	PFAM secretion protein HlyD family protein
IMX21_RS13150	COG1289	transmembrane transporter activity
IMX21_RS13155	COG1538	Outer membrane efflux protein
IMX21_RS13165	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IMX21_RS13170	COG1301	dicarboxylic acid transport
IMX21_RS13175	COG4235	cytochrome complex assembly
IMX21_RS13180	COG3088	subunit of a heme lyase
IMX21_RS13185	COG1138	Cytochrome C-type biogenesis protein
IMX21_RS13190	COG3301	Polysulphide reductase, NrfD
IMX21_RS13195	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS13200	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IMX21_RS13210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMX21_RS13215	COG3162	membrane
IMX21_RS13225	COG1357	PFAM Pentapeptide repeats (8 copies)
IMX21_RS13230	COG0025	NhaP-type Na H and K H
IMX21_RS13235	COG2252	PERMEase
IMX21_RS13240	COG0789	Transcriptional regulator
IMX21_RS13245	COG2207	Transcriptional regulator
IMX21_RS13250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IMX21_RS13260	COG0629	single-stranded DNA binding
IMX21_RS13265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMX21_RS13270	COG2315	Protein conserved in bacteria
IMX21_RS13275	COG0432	Pfam Uncharacterised protein family UPF0047
IMX21_RS13280	COG3700	Belongs to the class B bacterial acid phosphatase family
IMX21_RS13290	COG1448	Aminotransferase
IMX21_RS13295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMX21_RS13300	COG0305	Participates in initiation and elongation during chromosome replication
IMX21_RS13305	COG0604	alcohol dehydrogenase
IMX21_RS13315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMX21_RS13325	COG0735	belongs to the Fur family
IMX21_RS13330	COG3237	CsbD-like
IMX21_RS13335	COG0534	Mate efflux family protein
IMX21_RS13345	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IMX21_RS13365	COG1357	PFAM Pentapeptide repeats (8 copies)
IMX21_RS13380	COG3842	ATPase activity
IMX21_RS13385	COG2182	Extracellular solute-binding protein
IMX21_RS13390	COG1175	transmembrane transport
IMX21_RS13395	COG3833	ABC-type maltose transport systems, permease component
IMX21_RS13400	COG0477	Major facilitator Superfamily
IMX21_RS13400	COG2814	Major facilitator Superfamily
IMX21_RS13420	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMX21_RS13445	COG0527	aspartate kinase activity
IMX21_RS13455	COG1187	pseudouridine synthase activity
IMX21_RS13500	COG1283	sodium-dependent phosphate transmembrane transporter activity
IMX21_RS13505	COG1410	methionine synthase
IMX21_RS13505	COG0646	methionine synthase
IMX21_RS13510	COG1414	Transcriptional regulator
IMX21_RS13525	COG2224	Isocitrate lyase
IMX21_RS13530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IMX21_RS13540	COG0456	acetyltransferase
IMX21_RS13570	COG0151	Belongs to the GarS family
IMX21_RS13575	COG2204	response regulator
IMX21_RS13580	COG4191	Histidine kinase
IMX21_RS13585	COG3678	ATP-independent chaperone mediated protein folding
IMX21_RS13600	COG3068	Protein conserved in bacteria
IMX21_RS13635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMX21_RS13640	COG2104	thiamine diphosphate biosynthetic process
IMX21_RS13645	COG2022	thiamine diphosphate biosynthetic process
IMX21_RS13650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IMX21_RS13690	COG0250	Participates in transcription elongation, termination and antitermination
IMX21_RS13695	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMX21_RS13730	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IMX21_RS13730	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IMX21_RS13735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMX21_RS13760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMX21_RS13765	COG4206	TonB-dependent receptor
IMX21_RS13770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMX21_RS13780	COG1309	transcriptional regulator
IMX21_RS13785	COG0477	Major facilitator Superfamily
IMX21_RS13790	COG1473	amidohydrolase
IMX21_RS13795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMX21_RS13800	COG0583	DNA-binding transcription factor activity
IMX21_RS13805	COG0165	Argininosuccinate lyase
IMX21_RS13815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMX21_RS13830	COG2194	sulfuric ester hydrolase activity
IMX21_RS13835	COG2207	Transcriptional regulator
IMX21_RS13840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX21_RS13845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMX21_RS13850	COG1882	Formate acetyltransferase
IMX21_RS13855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX21_RS13865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS13865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS13865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMX21_RS13870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMX21_RS13875	COG0371	Dehydrogenase
IMX21_RS13880	COG3738	Protein conserved in bacteria
IMX21_RS13885	COG0697	spore germination
IMX21_RS13895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IMX21_RS13900	COG0527	aspartate kinase activity
IMX21_RS13900	COG0460	homoserine dehydrogenase
IMX21_RS13905	COG0626	cystathionine gamma-synthase activity
IMX21_RS13915	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IMX21_RS13930	COG3209	COG3209 Rhs family protein
IMX21_RS13940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMX21_RS13945	COG1609	Transcriptional regulator
IMX21_RS13950	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IMX21_RS13965	COG1575	Belongs to the MenA family. Type 1 subfamily
IMX21_RS13990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IMX21_RS14000	COG1494	fructose-1,6-bisphosphatase
IMX21_RS14010	COG0589	response to stress
IMX21_RS14015	COG3691	Protein conserved in bacteria
IMX21_RS14020	COG3152	Membrane
IMX21_RS14040	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IMX21_RS14055	COG3678	ATP-independent chaperone mediated protein folding
IMX21_RS14060	COG0745	RESPONSE REGULATOR receiver
IMX21_RS14065	COG2205	protein histidine kinase activity
IMX21_RS14070	COG2258	MOSC domain
IMX21_RS14080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMX21_RS14090	COG1917	Cupin 2, conserved barrel domain protein
IMX21_RS14090	COG4977	sequence-specific DNA binding
IMX21_RS14125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS14130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX21_RS14130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX21_RS14135	COG1363	Peptidase, m42
IMX21_RS14140	COG3711	transcriptional antiterminator
IMX21_RS14140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS14160	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS14165	COG2864	formate dehydrogenase
IMX21_RS14175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IMX21_RS14180	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IMX21_RS14195	COG0456	acetyltransferase
IMX21_RS14210	COG1011	Hydrolase
IMX21_RS14215	COG1349	DNA-binding transcription factor activity
IMX21_RS14220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX21_RS14225	COG2084	Dehydrogenase
IMX21_RS14230	COG3684	Belongs to the aldolase LacD family
IMX21_RS14235	COG2942	2-epimerase
IMX21_RS14240	COG2017	converts alpha-aldose to the beta-anomer
IMX21_RS14250	COG1501	Belongs to the glycosyl hydrolase 31 family
IMX21_RS14255	COG2211	Major facilitator Superfamily
IMX21_RS14260	COG2211	Major facilitator Superfamily
IMX21_RS14265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IMX21_RS14270	COG2271	Major facilitator Superfamily
IMX21_RS14275	COG1082	Xylose isomerase domain protein TIM barrel
IMX21_RS14280	COG2188	Transcriptional regulator
IMX21_RS14285	COG1217	gtp-binding protein TYPA
IMX21_RS14290	COG0174	glutamine synthetase
IMX21_RS14295	COG3852	Histidine kinase
IMX21_RS14300	COG2204	response regulator
IMX21_RS14310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMX21_RS14315	COG3078	GTPase activator activity
IMX21_RS14325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMX21_RS14325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMX21_RS14330	COG0204	Acyl-transferase
IMX21_RS14335	COG5339	Protein conserved in bacteria
IMX21_RS14340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IMX21_RS14345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMX21_RS14350	COG3084	Protein conserved in bacteria
IMX21_RS14355	COG0746	molybdenum cofactor guanylyltransferase activity
IMX21_RS14360	COG1763	Mo-molybdopterin cofactor biosynthetic process
IMX21_RS14390	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IMX21_RS14395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMX21_RS14400	COG1739	Uncharacterized protein family UPF0029
IMX21_RS14415	COG0183	Belongs to the thiolase family
IMX21_RS14420	COG0543	2 iron, 2 sulfur cluster binding
IMX21_RS14425	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IMX21_RS14430	COG0250	Participates in transcription elongation, termination and antitermination
IMX21_RS14435	COG0084	hydrolase, TatD family'
IMX21_RS14440	COG0805	protein transport
IMX21_RS14445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMX21_RS14450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMX21_RS14460	COG3165	ubiquinone biosynthetic process from chorismate
IMX21_RS14470	COG1322	Protein conserved in bacteria
IMX21_RS14475	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IMX21_RS14480	COG0412	Dienelactone hydrolase
IMX21_RS14485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMX21_RS14490	COG0583	DNA-binding transcription factor activity
IMX21_RS14495	COG0697	spore germination
IMX21_RS14500	COG0561	phosphatase activity
IMX21_RS14505	COG2267	carboxylic ester hydrolase activity
IMX21_RS14510	COG1280	lysine exporter protein (LysE YggA)
IMX21_RS14515	COG1280	lysine exporter protein (LysE YggA)
IMX21_RS14520	COG0514	ATP-dependent DNA helicase (RecQ)
IMX21_RS14525	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IMX21_RS14530	COG2050	protein possibly involved in aromatic compounds catabolism
IMX21_RS14535	COG2962	Rard protein
IMX21_RS14560	COG0598	Magnesium transport protein CorA
IMX21_RS14565	COG3698	Phosphodiester glycosidase
IMX21_RS14570	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
IMX21_RS14575	COG0210	DNA helicase
IMX21_RS14580	COG1011	Hydrolase
IMX21_RS14590	COG3159	Protein conserved in bacteria
IMX21_RS14600	COG5567	small periplasmic lipoprotein
IMX21_RS14615	COG3072	Adenylate cyclase
IMX21_RS14625	COG1587	Uroporphyrinogen-III synthase
IMX21_RS14630	COG2959	enzyme of heme biosynthesis
IMX21_RS14635	COG3071	HemY protein
IMX21_RS14640	COG3119	arylsulfatase activity
IMX21_RS14645	COG0641	radical SAM
IMX21_RS14675	COG1113	amino acid transport
IMX21_RS14690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMX21_RS14695	COG2244	polysaccharide biosynthetic process
IMX21_RS14700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMX21_RS14705	COG0456	acetyltransferase
IMX21_RS14710	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IMX21_RS14715	COG1088	dTDP-glucose 4,6-dehydratase activity
IMX21_RS14720	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IMX21_RS14725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IMX21_RS14730	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IMX21_RS14735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMX21_RS14740	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IMX21_RS14750	COG3118	belongs to the thioredoxin family
IMX21_RS14755	COG0513	Belongs to the DEAD box helicase family
IMX21_RS14765	COG0210	DNA helicase
IMX21_RS14770	COG3692	DNA binding
IMX21_RS14775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMX21_RS14785	COG0583	DNA-binding transcription factor activity
IMX21_RS14790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMX21_RS14800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMX21_RS14805	COG3978	acetolactate synthase activity
IMX21_RS14825	COG0606	chelatase, subunit chli
IMX21_RS14830	COG3085	chromosome segregation
IMX21_RS14870	COG2186	Transcriptional regulator
IMX21_RS14875	COG0477	Major facilitator Superfamily
IMX21_RS14880	COG1609	Transcriptional regulator
IMX21_RS14885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX21_RS14890	COG1879	ABC-type sugar transport system periplasmic component
IMX21_RS14895	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS14900	COG1129	ABC transporter
IMX21_RS14910	COG3158	transport of potassium into the cell
IMX21_RS14930	COG1522	sequence-specific DNA binding
IMX21_RS14935	COG0716	FMN binding
IMX21_RS14950	COG3312	ion transport
IMX21_RS14990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IMX21_RS15000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMX21_RS15025	COG3539	Fimbrial protein
IMX21_RS15035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IMX21_RS15040	COG0573	inorganic phosphate transmembrane transporter activity
IMX21_RS15045	COG0581	inorganic phosphate transmembrane transporter activity
IMX21_RS15050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMX21_RS15055	COG0704	Plays a role in the regulation of phosphate uptake
IMX21_RS15080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMX21_RS15085	COG2252	PERMEase
IMX21_RS15090	COG0431	NADPH-dependent FMN reductase
IMX21_RS15095	COG2091	lysine biosynthetic process via aminoadipic acid
IMX21_RS15110	COG0814	amino acid
IMX21_RS15165	COG0592	DNA-directed DNA polymerase activity
IMX21_RS15175	COG0187	DNA topoisomerase II activity
IMX21_RS15180	COG3753	Protein conserved in bacteria
IMX21_RS15185	COG0561	phosphatase activity
IMX21_RS15195	COG0644	oxidoreductase
IMX21_RS15200	COG0823	Involved in the tonB-independent uptake of proteins
IMX21_RS15205	COG5645	(Lipo)protein
IMX21_RS15225	COG2188	Transcriptional regulator
IMX21_RS15240	COG2207	Transcriptional regulator
IMX21_RS15245	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMX21_RS15250	COG3119	arylsulfatase activity
IMX21_RS15260	COG2149	membrane
IMX21_RS15270	COG0641	radical SAM
IMX21_RS15275	COG2814	Major facilitator Superfamily
IMX21_RS15290	COG0028	Belongs to the TPP enzyme family
IMX21_RS15295	COG0440	acetolactate synthase activity
IMX21_RS15315	COG2197	response regulator
IMX21_RS15320	COG3851	Histidine kinase
IMX21_RS15325	COG2271	Major facilitator Superfamily
IMX21_RS15330	COG2271	Major facilitator Superfamily
IMX21_RS15360	COG2814	Major facilitator Superfamily
IMX21_RS15370	COG1464	Belongs to the NlpA lipoprotein family
IMX21_RS15375	COG0697	spore germination
IMX21_RS15380	COG2814	Major facilitator Superfamily
IMX21_RS15550	COG5492	domain, Protein
IMX21_RS15605	COG4372	Transposase
IMX21_RS15610	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS15650	COG0582	viral genome integration into host DNA
IMX21_RS15660	COG2211	Major facilitator Superfamily
IMX21_RS15665	COG1501	Belongs to the glycosyl hydrolase 31 family
IMX21_RS15670	COG2982	Protein involved in outer membrane biogenesis
IMX21_RS15675	COG2233	PERMEase
IMX21_RS15680	COG0786	glutamate:sodium symporter activity
IMX21_RS15690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMX21_RS15695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMX21_RS15700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMX21_RS15710	COG0194	GDP metabolic process
IMX21_RS15720	COG2860	membrane
IMX21_RS15725	COG3645	SOS response
IMX21_RS15730	COG1561	YicC-like family, N-terminal region
IMX21_RS15755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMX21_RS15785	COG1519	Transferase
IMX21_RS15790	COG0859	PFAM glycosyl transferase family 9
IMX21_RS15795	COG0438	transferase activity, transferring glycosyl groups
IMX21_RS15800	COG0515	serine threonine protein kinase
IMX21_RS15810	COG3642	lipopolysaccharide core region biosynthetic process
IMX21_RS15830	COG0859	PFAM glycosyl transferase family 9
IMX21_RS15835	COG0859	PFAM glycosyl transferase family 9
IMX21_RS15850	COG0156	8-amino-7-oxononanoate synthase activity
IMX21_RS15860	COG1216	Glycosyl transferase, family 2
IMX21_RS15865	COG2861	carbohydrate metabolic process
IMX21_RS15870	COG4942	peptidase
IMX21_RS15880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMX21_RS15885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IMX21_RS15900	COG1045	serine acetyltransferase
IMX21_RS15905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IMX21_RS15915	COG2186	Transcriptional regulator
IMX21_RS15920	COG1620	l-lactate permease
IMX21_RS15925	COG5295	Hep Hag repeat protein
IMX21_RS15945	COG3722	fumarate hydratase activity
IMX21_RS15955	COG2213	PTS system mannitol-specific
IMX21_RS15955	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS15965	COG1566	PFAM secretion protein HlyD family protein
IMX21_RS15975	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IMX21_RS15980	COG3209	COG3209 Rhs family protein
IMX21_RS15985	COG0625	glutathione transferase activity
IMX21_RS15995	COG3276	selenocysteine insertion sequence binding
IMX21_RS16000	COG1454	alcohol dehydrogenase
IMX21_RS16010	COG1012	belongs to the aldehyde dehydrogenase family
IMX21_RS16020	COG1566	PFAM secretion protein HlyD family protein
IMX21_RS16025	COG0583	DNA-binding transcription factor activity
IMX21_RS16030	COG3713	MltA-interacting MipA family protein
IMX21_RS16040	COG2211	Major facilitator Superfamily
IMX21_RS16050	COG1414	Transcriptional regulator
IMX21_RS16055	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS16060	COG3977	Valine--pyruvate aminotransferase
IMX21_RS16065	COG0366	Alpha amylase catalytic
IMX21_RS16070	COG2992	FlgJ-related protein
IMX21_RS16075	COG1609	Transcriptional regulator
IMX21_RS16075	COG2207	Transcriptional regulator
IMX21_RS16080	COG4214	carbohydrate transport
IMX21_RS16090	COG4213	ABC transporter substrate-binding protein
IMX21_RS16100	COG1070	Carbohydrate kinase
IMX21_RS16105	COG4682	membrane
IMX21_RS16110	COG4682	membrane
IMX21_RS16115	COG3274	enterobacterial common antigen metabolic process
IMX21_RS16140	COG1278	Cold shock
IMX21_RS16145	COG2944	sequence-specific DNA binding
IMX21_RS16160	COG2885	chlorophyll binding
IMX21_RS16165	COG0243	molybdopterin cofactor binding
IMX21_RS16170	COG0456	acetyltransferase
IMX21_RS16175	COG2818	Glycosylase
IMX21_RS16180	COG5571	outer membrane autotransporter
IMX21_RS16185	COG2223	nitrite transmembrane transporter activity
IMX21_RS16190	COG3539	Fimbrial protein
IMX21_RS16195	COG3121	Chaperone
IMX21_RS16205	COG3539	Fimbrial protein
IMX21_RS16210	COG3539	Fimbrial protein
IMX21_RS16215	COG2194	sulfuric ester hydrolase activity
IMX21_RS16225	COG0747	negative chemotaxis
IMX21_RS16230	COG0601	transmembrane transport
IMX21_RS16235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMX21_RS16240	COG0444	Belongs to the ABC transporter superfamily
IMX21_RS16245	COG4608	Belongs to the ABC transporter superfamily
IMX21_RS16250	COG0814	amino acid
IMX21_RS16260	COG2194	sulfuric ester hydrolase activity
IMX21_RS16290	COG1215	transferase activity, transferring glycosyl groups
IMX21_RS16295	COG1215	transferase activity, transferring glycosyl groups
IMX21_RS16300	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IMX21_RS16310	COG2199	diguanylate cyclase activity
IMX21_RS16310	COG2200	EAL domain
IMX21_RS16320	COG0612	Peptidase, M16
IMX21_RS16330	COG2200	EAL domain
IMX21_RS16335	COG2982	Protein involved in outer membrane biogenesis
IMX21_RS16340	COG0477	Major facilitator Superfamily
IMX21_RS16345	COG1295	ribonuclease BN
IMX21_RS16350	COG0583	DNA-binding transcription factor activity
IMX21_RS16355	COG2197	response regulator
IMX21_RS16365	COG1858	cytochrome C peroxidase
IMX21_RS16370	COG0076	glutamate decarboxylase activity
IMX21_RS16375	COG2207	Transcriptional regulator
IMX21_RS16380	COG2207	Transcriptional regulator
IMX21_RS16400	COG4558	Periplasmic binding protein
IMX21_RS16405	COG4771	TonB-dependent receptor
IMX21_RS16410	COG3720	iron ion transport
IMX21_RS16415	COG2197	response regulator
IMX21_RS16420	COG3065	identical protein binding
IMX21_RS16430	COG1393	Belongs to the ArsC family
IMX21_RS16435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IMX21_RS16440	COG0640	Transcriptional regulator
IMX21_RS16450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMX21_RS16455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IMX21_RS16460	COG0339	signal peptide processing
IMX21_RS16470	COG3104	oligopeptide transport
IMX21_RS16475	COG0589	response to stress
IMX21_RS16485	COG0306	phosphate transporter
IMX21_RS16490	COG2081	HI0933 family
IMX21_RS16510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMX21_RS16515	COG0842	Transport permease protein
IMX21_RS16515	COG1129	ABC transporter
IMX21_RS16520	COG0842	Transport permease protein
IMX21_RS16535	COG0191	fructose-bisphosphate aldolase activity
IMX21_RS16550	COG3775	system Galactitol-specific IIC component
IMX21_RS16555	COG3414	Phosphotransferase system galactitol-specific IIB component
IMX21_RS16565	COG2188	Transcriptional regulator
IMX21_RS16575	COG1124	(ABC) transporter
IMX21_RS16580	COG0444	Belongs to the ABC transporter superfamily
IMX21_RS16585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMX21_RS16590	COG0601	transmembrane transport
IMX21_RS16595	COG0747	negative chemotaxis
IMX21_RS16600	COG2091	lysine biosynthetic process via aminoadipic acid
IMX21_RS16605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMX21_RS16610	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS16620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMX21_RS16645	COG1216	Glycosyl transferase, family 2
IMX21_RS16665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMX21_RS16675	COG0204	Acyl-transferase
IMX21_RS16695	COG0628	permease
IMX21_RS16700	COG0477	Major facilitator Superfamily
IMX21_RS16710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IMX21_RS16725	COG3714	YhhN family
IMX21_RS16735	COG3776	membrane
IMX21_RS16740	COG0742	ribosomal rna small subunit methyltransferase
IMX21_RS16745	COG0552	protein localization to endoplasmic reticulum
IMX21_RS16750	COG2884	Cell division ATP-binding protein ftsE
IMX21_RS16755	COG2177	Part of the ABC transporter FtsEX involved in
IMX21_RS16760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMX21_RS16765	COG0683	leucine binding
IMX21_RS16780	COG0456	acetyltransferase
IMX21_RS16785	COG0683	leucine binding
IMX21_RS16790	COG0559	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS16795	COG4177	L-phenylalanine transmembrane transporter activity
IMX21_RS16800	COG0411	ABC transporter
IMX21_RS16805	COG0410	ABC transporter
IMX21_RS16815	COG1653	transport
IMX21_RS16820	COG1175	transmembrane transport
IMX21_RS16830	COG3842	ATPase activity
IMX21_RS16835	COG0584	glycerophosphoryl diester phosphodiesterase
IMX21_RS16845	COG0405	Gamma-glutamyltransferase
IMX21_RS16855	COG1247	-acetyltransferase
IMX21_RS16860	COG0673	inositol 2-dehydrogenase activity
IMX21_RS16865	COG1741	Belongs to the pirin family
IMX21_RS16870	COG1609	Transcriptional regulator
IMX21_RS16875	COG3265	gluconokinase activity
IMX21_RS16880	COG2610	gluconate transmembrane transporter activity
IMX21_RS16885	COG0514	ATP-dependent DNA helicase (RecQ)
IMX21_RS16905	COG2095	MarC family integral membrane protein
IMX21_RS16910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMX21_RS16915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IMX21_RS16935	COG0058	SHG alpha-glucan phosphorylase activity
IMX21_RS16940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IMX21_RS16955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMX21_RS16970	COG1349	DNA-binding transcription factor activity
IMX21_RS16975	COG4650	regulator
IMX21_RS16980	COG1690	Belongs to the RtcB family
IMX21_RS17005	COG0058	SHG alpha-glucan phosphorylase activity
IMX21_RS17010	COG1640	4-alpha-glucanotransferase
IMX21_RS17015	COG2610	gluconate transmembrane transporter activity
IMX21_RS17025	COG1040	competence protein
IMX21_RS17035	COG5464	transposase or invertase
IMX21_RS17045	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IMX21_RS17050	COG1918	ferrous iron import across plasma membrane
IMX21_RS17055	COG2183	response to ionizing radiation
IMX21_RS17060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMX21_RS17080	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IMX21_RS17090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IMX21_RS17095	COG1011	Hydrolase
IMX21_RS17105	COG0494	nUDIX hydrolase
IMX21_RS17110	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IMX21_RS17115	COG4972	Pilus assembly protein
IMX21_RS17120	COG3166	PFAM Fimbrial assembly family protein
IMX21_RS17135	COG4796	Type ii and iii secretion system protein
IMX21_RS17150	COG3266	domain, Protein
IMX21_RS17155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IMX21_RS17160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IMX21_RS17165	COG0546	phosphoglycolate phosphatase activity
IMX21_RS17170	COG0180	Tryptophanyl-tRNA synthetase
IMX21_RS17175	COG2188	Transcriptional regulator
IMX21_RS17185	COG1082	Xylose isomerase domain protein TIM barrel
IMX21_RS17190	COG2222	sugar isomerase
IMX21_RS17195	COG0531	amino acid
IMX21_RS17210	COG2116	formate transmembrane transporter activity
IMX21_RS17215	COG2146	nitrite reductase [NAD(P)H] activity
IMX21_RS17220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMX21_RS17230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMX21_RS17240	COG2184	nucleotidyltransferase activity
IMX21_RS17245	COG0512	Glutamine amidotransferase of anthranilate synthase
IMX21_RS17250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMX21_RS17255	COG1289	transmembrane transporter activity
IMX21_RS17260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMX21_RS17265	COG1765	OsmC-like protein
IMX21_RS17270	COG3954	Phosphoribulokinase
IMX21_RS17280	COG0429	hydrolase of the alpha beta-hydrolase fold
IMX21_RS17285	COG0488	(ABC) transporter
IMX21_RS17300	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IMX21_RS17305	COG1047	Peptidyl-prolyl cis-trans
IMX21_RS17315	COG0545	Peptidyl-prolyl cis-trans isomerase
IMX21_RS17320	COG2964	Protein conserved in bacteria
IMX21_RS17390	COG0089	rRNA binding
IMX21_RS17480	COG0201	protein transport
IMX21_RS17520	COG0789	Transcriptional regulator
IMX21_RS17525	COG3036	rescue of stalled ribosome
IMX21_RS17535	COG0569	domain protein
IMX21_RS17555	COG0758	DNA mediated transformation
IMX21_RS17565	COG0551	DNA topoisomerase type I activity
IMX21_RS17570	COG0009	L-threonylcarbamoyladenylate synthase
IMX21_RS17585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IMX21_RS17625	COG1126	abc transporter atp-binding protein
IMX21_RS17630	COG0765	amino acid transport
IMX21_RS17635	COG4597	amino acid ABC transporter
IMX21_RS17640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX21_RS17655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMX21_RS17660	COG1309	transcriptional regulator
IMX21_RS17670	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IMX21_RS17680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMX21_RS17690	COG4145	pantothenate transmembrane transporter activity
IMX21_RS17695	COG3924	membrane
IMX21_RS17700	COG0439	Biotin carboxylase
IMX21_RS17705	COG0511	ligase activity, forming carbon-carbon bonds
IMX21_RS17710	COG0604	alcohol dehydrogenase
IMX21_RS17715	COG2199	diguanylate cyclase activity
IMX21_RS17715	COG2200	EAL domain
IMX21_RS17720	COG1077	Cell shape determining protein MreB Mrl
IMX21_RS17725	COG1792	Involved in formation and maintenance of cell shape
IMX21_RS17730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IMX21_RS17735	COG0424	maF-like protein
IMX21_RS17740	COG1530	ribonuclease E activity
IMX21_RS17745	COG3164	Protein of unknown function
IMX21_RS17750	COG0312	modulator of DNA gyrase
IMX21_RS17755	COG0583	DNA-binding transcription factor activity
IMX21_RS17775	COG2732	(Barnase) inhibitor
IMX21_RS17795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMX21_RS17800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMX21_RS17805	COG3105	Protein conserved in bacteria
IMX21_RS17810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IMX21_RS17825	COG0625	glutathione transferase activity
IMX21_RS17830	COG2969	positive regulation of protein catabolic process
IMX21_RS17835	COG3069	C4-dicarboxylate transmembrane transporter activity
IMX21_RS17865	COG2731	YhcH YjgK YiaL family protein
IMX21_RS17870	COG4804	nuclease activity
IMX21_RS17875	COG0493	'glutamate synthase
IMX21_RS17880	COG0067	glutamate synthase
IMX21_RS17880	COG0069	glutamate synthase activity
IMX21_RS17880	COG0070	glutamate synthase
IMX21_RS17885	COG1242	4 iron, 4 sulfur cluster binding
IMX21_RS17890	COG5002	protein histidine kinase activity
IMX21_RS17890	COG2198	Histidine kinase
IMX21_RS17890	COG0784	Response regulator, receiver
IMX21_RS17895	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IMX21_RS17905	COG0515	serine threonine protein kinase
IMX21_RS17910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS17925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMX21_RS17930	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IMX21_RS17935	COG1137	ATPase activity
IMX21_RS17940	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IMX21_RS17945	COG3117	lipopolysaccharide transmembrane transporter activity
IMX21_RS17950	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IMX21_RS17955	COG0517	IMP dehydrogenase activity
IMX21_RS17955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IMX21_RS17960	COG0530	calcium, potassium:sodium antiporter activity
IMX21_RS17965	COG1127	ABC transporter
IMX21_RS17970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IMX21_RS17975	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IMX21_RS17980	COG2854	intermembrane phospholipid transfer
IMX21_RS17985	COG3113	response to antibiotic
IMX21_RS17990	COG5007	Belongs to the BolA IbaG family
IMX21_RS18000	COG3423	Transcriptional regulator
IMX21_RS18005	COG0142	geranyltranstransferase activity
IMX21_RS18020	COG0697	spore germination
IMX21_RS18030	COG2027	D-alanyl-D-alanine carboxypeptidase
IMX21_RS18035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMX21_RS18040	COG1534	Rna-binding protein
IMX21_RS18050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMX21_RS18055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMX21_RS18065	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMX21_RS18075	COG2194	sulfuric ester hydrolase activity
IMX21_RS18095	COG0195	Participates in both transcription termination and antitermination
IMX21_RS18135	COG0513	Belongs to the DEAD box helicase family
IMX21_RS18140	COG0814	amino acid
IMX21_RS18145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX21_RS18150	COG0826	peptidase U32
IMX21_RS18155	COG0826	peptidase U32
IMX21_RS18160	COG3154	lipid carrier protein
IMX21_RS18165	COG3153	acetyltransferase
IMX21_RS18175	COG3787	Belongs to the UPF0306 family
IMX21_RS18180	COG0693	protein deglycase activity
IMX21_RS18185	COG0702	epimerase
IMX21_RS18190	COG0701	Predicted permease
IMX21_RS18195	COG2823	Periplasmic or secreted lipoprotein
IMX21_RS18215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMX21_RS18235	COG3188	usher protein
IMX21_RS18240	COG3121	Chaperone
IMX21_RS18245	COG3539	Fimbrial protein
IMX21_RS18255	COG3716	PTS system mannose fructose sorbose family IID component
IMX21_RS18265	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX21_RS18275	COG2222	sugar isomerase
IMX21_RS18280	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMX21_RS18305	COG2842	Transposition protein
IMX21_RS18335	COG4396	Host-nuclease inhibitor protein Gam
IMX21_RS18390	COG5566	PFAM Mor transcription activator
IMX21_RS18430	COG4373	Mu-like prophage FluMu protein gp28
IMX21_RS18435	COG4383	Mu-like prophage protein gp29
IMX21_RS18440	COG2369	cell adhesion
IMX21_RS18445	COG5005	Phage virion morphogenesis
IMX21_RS18450	COG4388	Caudovirus prohead serine protease
IMX21_RS18455	COG4397	Mu-like prophage major head subunit gpT
IMX21_RS18480	COG4386	tail sheath protein
IMX21_RS18490	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
IMX21_RS18510	COG4384	Bacteriophage Mu Gp45 protein
IMX21_RS18520	COG3299	homolog of phage Mu protein gp47
IMX21_RS18545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IMX21_RS18585	COG3716	PTS system mannose fructose sorbose family IID component
IMX21_RS18595	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX21_RS18605	COG1349	DNA-binding transcription factor activity
IMX21_RS18615	COG2002	toxin-antitoxin pair type II binding
IMX21_RS18620	COG2721	sulfolactate sulfo-lyase activity
IMX21_RS18625	COG2271	Major facilitator Superfamily
IMX21_RS18635	COG2084	Dehydrogenase
IMX21_RS18640	COG1929	Belongs to the glycerate kinase type-1 family
IMX21_RS18665	COG0583	DNA-binding transcription factor activity
IMX21_RS18670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMX21_RS18680	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMX21_RS18685	COG1882	Formate acetyltransferase
IMX21_RS18690	COG0251	oxidation-reduction process
IMX21_RS18695	COG1760	l-serine dehydratase
IMX21_RS18700	COG0814	amino acid
IMX21_RS18715	COG1741	Belongs to the pirin family
IMX21_RS18720	COG0583	DNA-binding transcription factor activity
IMX21_RS18725	COG3152	Membrane
IMX21_RS18730	COG3152	Membrane
IMX21_RS18735	COG0435	Glutathione S-transferase
IMX21_RS18740	COG2259	Doxx family
IMX21_RS18750	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IMX21_RS18755	COG4575	ribosome binding
IMX21_RS18760	COG1422	Protein of unknown function (DUF1090)
IMX21_RS18770	COG0586	Pfam SNARE associated Golgi protein
IMX21_RS18775	COG2186	Transcriptional regulator
IMX21_RS18780	COG2271	Major facilitator Superfamily
IMX21_RS18790	COG2721	sulfolactate sulfo-lyase activity
IMX21_RS18800	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IMX21_RS18805	COG0861	Integral membrane protein TerC family
IMX21_RS18810	COG0673	inositol 2-dehydrogenase activity
IMX21_RS18815	COG2949	membrane
IMX21_RS18820	COG1451	nucleotide metabolic process
IMX21_RS18830	COG4680	protein conserved in bacteria
IMX21_RS18835	COG5499	transcription regulator containing HTH domain
IMX21_RS18840	COG1902	pentaerythritol trinitrate reductase activity
IMX21_RS18840	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMX21_RS18845	COG3408	Glycogen debranching enzyme
IMX21_RS18845	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IMX21_RS18855	COG0531	amino acid
IMX21_RS18860	COG2731	YhcH YjgK YiaL family protein
IMX21_RS18865	COG3250	beta-galactosidase activity
IMX21_RS18870	COG1609	Transcriptional regulator
IMX21_RS18875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMX21_RS18885	COG0840	transmembrane signaling receptor activity
IMX21_RS18890	COG1695	Transcriptional regulator
IMX21_RS18895	COG2375	cellular response to nickel ion
IMX21_RS18910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMX21_RS18915	COG0358	DNA primase activity
IMX21_RS18920	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IMX21_RS18925	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMX21_RS18930	COG0471	metal ion transport
IMX21_RS18935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IMX21_RS18940	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IMX21_RS18945	COG0583	DNA-binding transcription factor activity
IMX21_RS18955	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMX21_RS18970	COG4991	sh3 domain protein
IMX21_RS18975	COG3025	triphosphatase activity
IMX21_RS19000	COG2268	Band 7 protein
IMX21_RS19005	COG1585	Membrane protein implicated in regulation of membrane protease activity
IMX21_RS19035	COG3384	dioxygenase
IMX21_RS19040	COG0754	glutathionylspermidine amidase activity
IMX21_RS19050	COG1538	Outer membrane efflux protein
IMX21_RS19055	COG0494	nUDIX hydrolase
IMX21_RS19060	COG3151	Protein conserved in bacteria
IMX21_RS19065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IMX21_RS19070	COG3150	esterase
IMX21_RS19075	COG0187	DNA topoisomerase II activity
IMX21_RS19080	COG4774	siderophore transport
IMX21_RS19085	COG1120	ATPase activity
IMX21_RS19090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMX21_RS19095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMX21_RS19105	COG1737	Transcriptional regulator
IMX21_RS19110	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IMX21_RS19115	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMX21_RS19120	COG0642	Histidine kinase
IMX21_RS19125	COG0745	RESPONSE REGULATOR receiver
IMX21_RS19130	COG3111	PFAM Bacterial OB fold (BOF) protein
IMX21_RS19135	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IMX21_RS19140	COG4166	transmembrane transport
IMX21_RS19145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMX21_RS19150	COG0204	Acyl-transferase
IMX21_RS19155	COG2132	Multicopper oxidase
IMX21_RS19160	COG1032	radical SAM domain protein
IMX21_RS19165	COG4238	major outer membrane lipoprotein
IMX21_RS19175	COG0656	L-ascorbic acid biosynthetic process
IMX21_RS19180	COG1979	alcohol dehydrogenase
IMX21_RS19185	COG2207	Transcriptional regulator
IMX21_RS19190	COG0586	Pfam SNARE associated Golgi protein
IMX21_RS19195	COG0626	cystathionine gamma-synthase activity
IMX21_RS19200	COG0811	peptide transport
IMX21_RS19205	COG0848	biopolymer transport protein
IMX21_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS19220	COG0667	Aldo Keto reductase
IMX21_RS19235	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IMX21_RS19240	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS19245	COG5557	Pfam Polysulphide reductase, NrfD
IMX21_RS19250	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IMX21_RS19255	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IMX21_RS19260	COG1773	rubredoxin
IMX21_RS19265	COG0375	protein maturation
IMX21_RS19270	COG0298	carbon dioxide binding
IMX21_RS19275	COG0625	glutathione transferase activity
IMX21_RS19280	COG0754	glutathionylspermidine amidase activity
IMX21_RS19305	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS19310	COG4372	Transposase
IMX21_RS19315	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS19385	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS19400	COG0582	viral genome integration into host DNA
IMX21_RS19410	COG1811	Na channel or pump
IMX21_RS19415	COG1982	Orn Lys Arg decarboxylase major
IMX21_RS19420	COG2211	Major facilitator Superfamily
IMX21_RS19435	COG1194	a g-specific adenine glycosylase
IMX21_RS19445	COG3171	Protein conserved in bacteria
IMX21_RS19455	COG0252	asparaginase activity
IMX21_RS19465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMX21_RS19470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMX21_RS19480	COG0762	integral membrane protein
IMX21_RS19485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMX21_RS19490	COG2805	Type II/IV secretion system protein
IMX21_RS19505	COG0189	ligase activity
IMX21_RS19510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMX21_RS19515	COG2356	endonuclease I
IMX21_RS19520	COG3091	SprT-like family
IMX21_RS19525	COG2814	Major facilitator Superfamily
IMX21_RS19545	COG1166	arginine decarboxylase activity
IMX21_RS19560	COG0501	Belongs to the peptidase M48B family
IMX21_RS19565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMX21_RS19570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS19575	COG2213	PTS system mannitol-specific
IMX21_RS19580	COG1063	alcohol dehydrogenase
IMX21_RS19585	COG1494	fructose-1,6-bisphosphatase
IMX21_RS19595	COG1072	(Pantothenic acid kinase))
IMX21_RS19600	COG1122	ATPase activity
IMX21_RS19605	COG1122	ATPase activity
IMX21_RS19630	COG0126	phosphoglycerate kinase activity
IMX21_RS19635	COG0191	fructose-bisphosphate aldolase activity
IMX21_RS19640	COG0668	transmembrane transport
IMX21_RS19650	COG2968	Membrane
IMX21_RS19660	COG0427	acetyl-CoA hydrolase
IMX21_RS19665	COG1024	Enoyl-CoA hydratase
IMX21_RS19670	COG1703	isobutyryl-CoA mutase activity
IMX21_RS19675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMX21_RS19675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMX21_RS19690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMX21_RS19705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMX21_RS19725	COG0006	proline dipeptidase activity
IMX21_RS19730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMX21_RS19735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMX21_RS19760	COG2723	6-phospho-beta-galactosidase activity
IMX21_RS19770	COG1272	protein, Hemolysin III
IMX21_RS19780	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IMX21_RS19790	COG0716	FMN binding
IMX21_RS19795	COG4974	Belongs to the 'phage' integrase family
IMX21_RS19800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IMX21_RS19805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IMX21_RS19815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMX21_RS19835	COG2233	PERMEase
IMX21_RS19840	COG0493	'glutamate synthase
IMX21_RS19840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS19850	COG2252	PERMEase
IMX21_RS19855	COG0402	S-adenosylhomocysteine deaminase activity
IMX21_RS19860	COG2233	PERMEase
IMX21_RS19865	COG2080	2 iron, 2 sulfur cluster binding
IMX21_RS19865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IMX21_RS19870	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IMX21_RS19875	COG0402	S-adenosylhomocysteine deaminase activity
IMX21_RS19880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS19880	COG0493	'glutamate synthase
IMX21_RS19885	COG2068	MobA-Related Protein
IMX21_RS19890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMX21_RS19895	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IMX21_RS19895	COG3608	succinylglutamate desuccinylase aspartoacylase
IMX21_RS19900	COG0549	Belongs to the carbamate kinase family
IMX21_RS19910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMX21_RS19915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMX21_RS19920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMX21_RS19925	COG3829	transcription factor binding
IMX21_RS19930	COG2080	2 iron, 2 sulfur cluster binding
IMX21_RS19935	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IMX21_RS19940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IMX21_RS19945	COG4942	peptidase
IMX21_RS19965	COG2207	Transcriptional regulator
IMX21_RS20070	COG2197	response regulator
IMX21_RS20075	COG0741	lytic transglycosylase activity
IMX21_RS20085	COG0457	Tetratricopeptide repeat
IMX21_RS20085	COG3710	Transcriptional regulator
IMX21_RS20090	COG0457	Tetratricopeptide repeat
IMX21_RS20115	COG3710	Transcriptional regulator
IMX21_RS20120	COG2771	luxR family
IMX21_RS20125	COG0814	amino acid
IMX21_RS20130	COG0183	Belongs to the thiolase family
IMX21_RS20140	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS20145	COG2814	Major facilitator Superfamily
IMX21_RS20150	COG1794	racemase activity, acting on amino acids and derivatives
IMX21_RS20155	COG0583	DNA-binding transcription factor activity
IMX21_RS20165	COG1609	Transcriptional regulator
IMX21_RS20180	COG0667	Aldo Keto reductase
IMX21_RS20190	COG0861	Integral membrane protein TerC family
IMX21_RS20205	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
IMX21_RS20220	COG2165	general secretion pathway protein
IMX21_RS20225	COG4795	General secretion pathway protein
IMX21_RS20235	COG4967	type IV pilus modification protein PilV
IMX21_RS20240	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IMX21_RS20245	COG1025	Belongs to the peptidase M16 family
IMX21_RS20250	COG1074	ATP-dependent DNA helicase activity
IMX21_RS20255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMX21_RS20260	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IMX21_RS20260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMX21_RS20265	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMX21_RS20285	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IMX21_RS20290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IMX21_RS20295	COG2166	iron-sulfur cluster assembly
IMX21_RS20300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMX21_RS20310	COG0583	DNA-binding transcription factor activity
IMX21_RS20315	COG2363	Small membrane protein
IMX21_RS20325	COG1349	DNA-binding transcription factor activity
IMX21_RS20335	COG1070	Carbohydrate kinase
IMX21_RS20345	COG0738	Major facilitator superfamily
IMX21_RS20350	COG0235	Class ii aldolase
IMX21_RS20355	COG1454	alcohol dehydrogenase
IMX21_RS20365	COG1760	l-serine dehydratase
IMX21_RS20370	COG0814	amino acid
IMX21_RS20375	COG1611	Belongs to the LOG family
IMX21_RS20390	COG3098	single-species biofilm formation
IMX21_RS20395	COG0564	pseudouridine synthase activity
IMX21_RS20400	COG0716	FMN binding
IMX21_RS20405	COG2271	Major facilitator Superfamily
IMX21_RS20415	COG4948	Mandelate Racemase Muconate Lactonizing
IMX21_RS20420	COG2205	protein histidine kinase activity
IMX21_RS20420	COG4999	Histidine kinase
IMX21_RS20420	COG3850	Histidine kinase
IMX21_RS20420	COG3437	response regulator, receiver
IMX21_RS20425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMX21_RS20430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMX21_RS20435	COG2336	PFAM SpoVT AbrB
IMX21_RS20440	COG2337	Toxic component of a toxin-antitoxin (TA) module
IMX21_RS20445	COG3956	TIGRFAM MazG family protein
IMX21_RS20460	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IMX21_RS20470	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IMX21_RS20480	COG0602	queuosine metabolic process
IMX21_RS20485	COG1070	Carbohydrate kinase
IMX21_RS20490	COG2223	nitrite transmembrane transporter activity
IMX21_RS20495	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS20500	COG0277	FAD linked oxidase domain protein
IMX21_RS20510	COG2086	electron transfer activity
IMX21_RS20520	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IMX21_RS20525	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IMX21_RS20530	COG0644	oxidoreductase
IMX21_RS20535	COG0720	synthase
IMX21_RS20540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IMX21_RS20560	COG1203	CRISPR-associated helicase, Cas3
IMX21_RS20575	COG1857	crispr-associated protein
IMX21_RS20590	COG1518	maintenance of DNA repeat elements
IMX21_RS20595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX21_RS20600	COG2234	aminopeptidase activity
IMX21_RS20655	COG1388	LysM domain
IMX21_RS20655	COG4942	peptidase
IMX21_RS20660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMX21_RS20665	COG1846	Transcriptional regulator
IMX21_RS20670	COG0163	prenyltransferase activity
IMX21_RS20675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IMX21_RS20685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IMX21_RS20705	COG3604	Transcriptional regulator
IMX21_RS20710	COG0309	Hydrogenase expression formation protein (HypE)
IMX21_RS20715	COG0409	Hydrogenase expression formation protein
IMX21_RS20720	COG0298	carbon dioxide binding
IMX21_RS20725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IMX21_RS20730	COG0375	protein maturation
IMX21_RS20740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS20745	COG0651	ATP synthesis coupled electron transport
IMX21_RS20750	COG0650	Formate hydrogenlyase subunit 4
IMX21_RS20755	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IMX21_RS20755	COG3261	NADH dehydrogenase
IMX21_RS20760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMX21_RS20765	COG3260	NADH ubiquinone oxidoreductase 20
IMX21_RS20775	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IMX21_RS20780	COG2723	6-phospho-beta-galactosidase activity
IMX21_RS20785	COG1263	PTS System
IMX21_RS20785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX21_RS20790	COG1609	Transcriptional regulator
IMX21_RS20795	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS20800	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IMX21_RS20810	COG0426	domain, Protein
IMX21_RS20810	COG1773	rubredoxin
IMX21_RS20820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IMX21_RS20820	COG0517	IMP dehydrogenase activity
IMX21_RS20825	COG1349	DNA-binding transcription factor activity
IMX21_RS20830	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS20835	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS20855	COG2951	lytic endotransglycosylase activity
IMX21_RS20860	COG1546	Belongs to the CinA family
IMX21_RS20875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMX21_RS20880	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IMX21_RS20910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMX21_RS20915	COG1238	metal cluster binding
IMX21_RS20930	COG2814	Major facilitator Superfamily
IMX21_RS20935	COG1566	PFAM secretion protein HlyD family protein
IMX21_RS20940	COG1846	Transcriptional regulator
IMX21_RS20950	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IMX21_RS20955	COG2814	Major facilitator Superfamily
IMX21_RS20960	COG2113	Glycine betaine
IMX21_RS20965	COG4176	ABC-type proline glycine betaine transport system permease component
IMX21_RS20970	COG4175	Glycine betaine
IMX21_RS20975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMX21_RS20980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMX21_RS20990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IMX21_RS20995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMX21_RS21005	COG4575	ribosome binding
IMX21_RS21020	COG2916	Histone family protein nucleoid-structuring protein H-NS
IMX21_RS21025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMX21_RS21030	COG0640	Transcriptional regulator
IMX21_RS21035	COG0401	homolog of Blt101
IMX21_RS21040	COG1652	LysM domain
IMX21_RS21045	COG1802	Transcriptional regulator
IMX21_RS21050	COG1113	amino acid transport
IMX21_RS21055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMX21_RS21060	COG1012	belongs to the aldehyde dehydrogenase family
IMX21_RS21065	COG0579	oxidoreductase
IMX21_RS21100	COG3468	outer membrane autotransporter barrel domain protein
IMX21_RS21210	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS21275	COG2867	negative regulation of translational initiation
IMX21_RS21285	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMX21_RS21290	COG0497	DNA recombination
IMX21_RS21305	COG4536	flavin adenine dinucleotide binding
IMX21_RS21310	COG4137	Cytochrome C assembly protein
IMX21_RS21315	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMX21_RS21340	COG2885	chlorophyll binding
IMX21_RS21345	COG2199	diguanylate cyclase activity
IMX21_RS21360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMX21_RS21365	COG0287	Prephenate dehydrogenase
IMX21_RS21365	COG1605	Chorismate mutase
IMX21_RS21370	COG0077	Prephenate dehydratase
IMX21_RS21370	COG1605	Chorismate mutase
IMX21_RS21380	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMX21_RS21385	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMX21_RS21390	COG0564	pseudouridine synthase activity
IMX21_RS21400	COG0542	response to heat
IMX21_RS21425	COG0477	Major facilitator Superfamily
IMX21_RS21430	COG5544	Lipoprotein
IMX21_RS21435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMX21_RS21440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMX21_RS21440	COG0045	succinate-CoA ligase (ADP-forming) activity
IMX21_RS21440	COG1042	CoA-binding domain protein
IMX21_RS21445	COG3148	PFAM DTW domain containing protein
IMX21_RS21450	COG3118	belongs to the thioredoxin family
IMX21_RS21455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMX21_RS21470	COG1280	lysine exporter protein (LysE YggA)
IMX21_RS21475	COG0583	DNA-binding transcription factor activity
IMX21_RS21480	COG0513	Belongs to the DEAD box helicase family
IMX21_RS21485	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IMX21_RS21490	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IMX21_RS21500	COG1595	DNA-templated transcription, initiation
IMX21_RS21505	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IMX21_RS21510	COG3026	antisigma factor binding
IMX21_RS21515	COG3086	response to oxidative stress
IMX21_RS21525	COG0681	Belongs to the peptidase S26 family
IMX21_RS21545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IMX21_RS21560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS21565	COG1737	Transcriptional regulator
IMX21_RS21570	COG0560	Phosphoserine phosphatase
IMX21_RS21575	COG0590	tRNA wobble adenosine to inosine editing
IMX21_RS21580	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IMX21_RS21585	COG0047	phosphoribosylformylglycinamidine synthase activity
IMX21_RS21585	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMX21_RS21590	COG2205	protein histidine kinase activity
IMX21_RS21595	COG3170	Tfp pilus assembly protein FimV
IMX21_RS21600	COG2204	response regulator
IMX21_RS21605	COG0347	Belongs to the P(II) protein family
IMX21_RS21610	COG1017	nitric oxide dioxygenase activity
IMX21_RS21610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMX21_RS21620	COG1940	carbohydrate kinase activity
IMX21_RS21625	COG0457	Tetratricopeptide repeat
IMX21_RS21630	COG1879	ABC-type sugar transport system periplasmic component
IMX21_RS21635	COG1129	ABC transporter
IMX21_RS21640	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS21645	COG1063	alcohol dehydrogenase
IMX21_RS21650	COG1063	alcohol dehydrogenase
IMX21_RS21655	COG2017	converts alpha-aldose to the beta-anomer
IMX21_RS21660	COG2259	Doxx family
IMX21_RS21685	COG4638	Rieske (2fe-2S)
IMX21_RS21690	COG0583	DNA-binding transcription factor activity
IMX21_RS21695	COG2814	Major facilitator Superfamily
IMX21_RS21700	COG3711	transcriptional antiterminator
IMX21_RS21705	COG1073	alpha beta
IMX21_RS21710	COG0483	inositol monophosphate 1-phosphatase activity
IMX21_RS21730	COG0822	iron-sulfur transferase activity
IMX21_RS21750	COG0633	Ferredoxin
IMX21_RS21755	COG2975	iron-sulfur cluster assembly
IMX21_RS21770	COG2897	thiosulfate sulfurtransferase activity
IMX21_RS21775	COG2373	Large extracellular alpha-helical protein
IMX21_RS21780	COG4953	penicillin-binding protein 1C
IMX21_RS21785	COG0243	molybdopterin cofactor binding
IMX21_RS21790	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS21795	COG3302	dmso reductase anchor subunit
IMX21_RS21830	COG2976	Protein conserved in bacteria
IMX21_RS21845	COG1645	bacterial-type flagellum-dependent swarming motility
IMX21_RS21855	COG0517	IMP dehydrogenase activity
IMX21_RS21855	COG0516	GMP reductase activity
IMX21_RS21870	COG3133	Outer membrane lipoprotein
IMX21_RS21885	COG2200	EAL domain
IMX21_RS21890	COG0248	Ppx GppA phosphatase
IMX21_RS21895	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMX21_RS21900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMX21_RS21915	COG2233	PERMEase
IMX21_RS21925	COG1393	Belongs to the ArsC family
IMX21_RS21930	COG4783	chaperone-mediated protein folding
IMX21_RS21935	COG0628	permease
IMX21_RS21940	COG2116	formate transmembrane transporter activity
IMX21_RS21945	COG3604	Transcriptional regulator
IMX21_RS21955	COG3260	NADH ubiquinone oxidoreductase 20
IMX21_RS21960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMX21_RS21965	COG3261	NADH dehydrogenase
IMX21_RS21965	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IMX21_RS21970	COG0651	ATP synthesis coupled electron transport
IMX21_RS21975	COG4237	Hydrogenase 4 membrane
IMX21_RS21980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMX21_RS21985	COG0650	Formate hydrogenlyase subunit 4
IMX21_RS21990	COG0651	ATP synthesis coupled electron transport
IMX21_RS21995	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS22000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IMX21_RS22005	COG2716	regulation of RNA biosynthetic process
IMX21_RS22015	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IMX21_RS22025	COG2321	neutral zinc metallopeptidase
IMX21_RS22035	COG0400	carboxylic ester hydrolase activity
IMX21_RS22050	COG1393	Belongs to the ArsC family
IMX21_RS22060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMX21_RS22065	COG3850	Histidine kinase
IMX21_RS22070	COG0493	'glutamate synthase
IMX21_RS22070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS22080	COG5342	invasion associated locus B
IMX21_RS22085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMX21_RS22090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMX21_RS22095	COG0280	phosphate acetyltransferase
IMX21_RS22095	COG0281	malic enzyme
IMX21_RS22100	COG4810	utilization protein
IMX21_RS22105	COG4917	ethanolamine utilization protein
IMX21_RS22110	COG4766	ethanolamine catabolic process
IMX21_RS22115	COG4812	Cobalamin adenosyltransferase
IMX21_RS22120	COG0280	phosphate acetyltransferase
IMX21_RS22125	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IMX21_RS22130	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IMX21_RS22135	COG1012	belongs to the aldehyde dehydrogenase family
IMX21_RS22140	COG4820	ethanolamine utilization protein (EutJ)
IMX21_RS22145	COG1454	alcohol dehydrogenase
IMX21_RS22150	COG3192	ethanolamine utilization protein
IMX21_RS22155	COG4819	ethanolamine utilization protein
IMX21_RS22160	COG4303	Ethanolamine ammonia lyase large subunit
IMX21_RS22170	COG4816	utilization protein
IMX21_RS22175	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IMX21_RS22180	COG2207	Transcriptional regulator
IMX21_RS22190	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMX21_RS22210	COG2837	iron assimilation
IMX21_RS22215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IMX21_RS22220	COG1263	PTS System
IMX21_RS22220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX21_RS22235	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS22240	COG4150	thiosulfate binding
IMX21_RS22245	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IMX21_RS22250	COG4208	sulfate ABC transporter
IMX21_RS22255	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IMX21_RS22260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMX21_RS22275	COG2190	(PTS) system
IMX21_RS22280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMX21_RS22285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS22290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMX21_RS22310	COG3530	Putative quorum-sensing-regulated virulence factor
IMX21_RS22315	COG0385	Bile acid
IMX21_RS22360	COG0675	Transposase, IS605 OrfB family
IMX21_RS22365	COG3415	Transposase
IMX21_RS22370	COG3415	Transposase
IMX21_RS22385	COG2199	diguanylate cyclase activity
IMX21_RS22385	COG2200	EAL domain
IMX21_RS22390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMX21_RS22415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX21_RS22420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX21_RS22425	COG0006	proline dipeptidase activity
IMX21_RS22430	COG1363	Peptidase, m42
IMX21_RS22435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS22435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMX21_RS22435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS22440	COG2207	Transcriptional regulator
IMX21_RS22445	COG3279	Response regulator of the LytR AlgR family
IMX21_RS22450	COG3275	phosphorelay sensor kinase activity
IMX21_RS22455	COG0436	Aminotransferase
IMX21_RS22465	COG1560	Kdo2-lipid A biosynthetic process
IMX21_RS22490	COG0028	Belongs to the TPP enzyme family
IMX21_RS22495	COG0679	Auxin Efflux Carrier
IMX21_RS22505	COG0784	Response regulator, receiver
IMX21_RS22505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX21_RS22505	COG2198	Histidine kinase
IMX21_RS22505	COG2205	protein histidine kinase activity
IMX21_RS22510	COG2197	response regulator
IMX21_RS22515	COG1566	PFAM secretion protein HlyD family protein
IMX21_RS22520	COG0477	Major facilitator Superfamily
IMX21_RS22595	COG0582	viral genome integration into host DNA
IMX21_RS22605	COG2116	formate transmembrane transporter activity
IMX21_RS22610	COG2853	Lipoprotein
IMX21_RS22620	COG2067	long-chain fatty acid transport protein
IMX21_RS22625	COG3691	Protein conserved in bacteria
IMX21_RS22635	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMX21_RS22635	COG1024	Enoyl-CoA hydratase
IMX21_RS22640	COG2062	phosphohistidine phosphatase, SixA
IMX21_RS22645	COG3539	Fimbrial protein
IMX21_RS22650	COG3188	usher protein
IMX21_RS22655	COG3121	Chaperone
IMX21_RS22660	COG3539	Fimbrial protein
IMX21_RS22665	COG3539	Fimbrial protein
IMX21_RS22670	COG3539	Fimbrial protein
IMX21_RS22700	COG0730	response to heat
IMX21_RS22705	COG3101	peptidyl-lysine hydroxylation
IMX21_RS22715	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IMX21_RS22715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMX21_RS22720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMX21_RS22725	COG2814	Major facilitator Superfamily
IMX21_RS22740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMX21_RS22750	COG0586	Pfam SNARE associated Golgi protein
IMX21_RS22760	COG0285	dihydrofolate synthase activity
IMX21_RS22765	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IMX21_RS22770	COG1286	toxin biosynthetic process
IMX21_RS22775	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMX21_RS22780	COG0163	prenyltransferase activity
IMX21_RS22785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX21_RS22790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX21_RS22795	COG4215	(ABC) transporter
IMX21_RS22800	COG4160	amino acid transport
IMX21_RS22805	COG4598	ABC transporter
IMX21_RS22810	COG5464	transposase or invertase
IMX21_RS22815	COG1090	epimerase
IMX21_RS22820	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMX21_RS22825	COG0625	glutathione transferase activity
IMX21_RS22830	COG0625	glutathione transferase activity
IMX21_RS22835	COG0622	Phosphoesterase
IMX21_RS22840	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IMX21_RS22845	COG1288	antiporter activity
IMX21_RS22850	COG0857	belongs to the CobB CobQ family
IMX21_RS22850	COG0280	phosphate acetyltransferase
IMX21_RS22855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMX21_RS22870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMX21_RS22875	COG0471	metal ion transport
IMX21_RS22875	COG0490	domain, Protein
IMX21_RS22885	COG0436	Aminotransferase
IMX21_RS22890	COG0583	DNA-binding transcription factor activity
IMX21_RS22910	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IMX21_RS22915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IMX21_RS22920	COG1034	ATP synthesis coupled electron transport
IMX21_RS22935	COG0839	Belongs to the complex I subunit 6 family
IMX21_RS22945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMX21_RS22950	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMX21_RS22970	COG5160	protein modification by small protein removal
IMX21_RS22975	COG1234	tRNA 3'-trailer cleavage
IMX21_RS22980	COG2153	protein acetylation
IMX21_RS22985	COG4575	ribosome binding
IMX21_RS22990	COG1169	isochorismate synthase
IMX21_RS23005	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IMX21_RS23015	COG0318	PFAM AMP-dependent synthetase and ligase
IMX21_RS23060	COG0406	alpha-ribazole phosphatase activity
IMX21_RS23080	COG1414	Transcriptional regulator
IMX21_RS23085	COG4948	Mandelate Racemase Muconate Lactonizing
IMX21_RS23090	COG2271	Major facilitator Superfamily
IMX21_RS23105	COG3836	Belongs to the HpcH HpaI aldolase family
IMX21_RS23110	COG5464	transposase or invertase
IMX21_RS23115	COG0247	lactate metabolic process
IMX21_RS23125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMX21_RS23130	COG2271	Major facilitator Superfamily
IMX21_RS23135	COG0584	glycerophosphoryl diester phosphodiesterase
IMX21_RS23145	COG0583	DNA-binding transcription factor activity
IMX21_RS23150	COG2814	Major facilitator Superfamily
IMX21_RS23155	COG3642	lipopolysaccharide core region biosynthetic process
IMX21_RS23160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMX21_RS23165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMX21_RS23170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMX21_RS23175	COG3468	outer membrane autotransporter barrel domain protein
IMX21_RS23185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMX21_RS23190	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
IMX21_RS23195	COG3234	Protein of unknown function (DUF1175)
IMX21_RS23200	COG2373	Large extracellular alpha-helical protein
IMX21_RS23205	COG5445	Predicted secreted protein (DUF2300)
IMX21_RS23210	COG5445	Predicted secreted protein (DUF2300)
IMX21_RS23215	COG4676	Protein conserved in bacteria
IMX21_RS23220	COG2205	protein histidine kinase activity
IMX21_RS23220	COG0784	Response regulator, receiver
IMX21_RS23225	COG2197	response regulator
IMX21_RS23230	COG0642	Histidine kinase
IMX21_RS23230	COG2198	Histidine kinase
IMX21_RS23235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IMX21_RS23240	COG1477	protein flavinylation
IMX21_RS23245	COG2169	Transcriptional regulator
IMX21_RS23245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMX21_RS23250	COG3145	DNA-N1-methyladenine dioxygenase activity
IMX21_RS23255	COG4615	Cyclic peptide transporter
IMX21_RS23270	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS23270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMX21_RS23275	COG3062	negative regulation of establishment of protein localization
IMX21_RS23285	COG0437	4 iron, 4 sulfur cluster binding
IMX21_RS23290	COG0348	domain, Protein
IMX21_RS23295	COG3043	anaerobic respiration
IMX21_RS23300	COG3005	denitrification pathway
IMX21_RS23305	COG4133	protoheme IX ABC transporter activity
IMX21_RS23310	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMX21_RS23315	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMX21_RS23320	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMX21_RS23330	COG1138	Cytochrome C-type biogenesis protein
IMX21_RS23335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMX21_RS23340	COG3088	subunit of a heme lyase
IMX21_RS23340	COG4235	cytochrome complex assembly
IMX21_RS23345	COG2197	response regulator
IMX21_RS23350	COG3468	outer membrane autotransporter barrel domain protein
IMX21_RS23360	COG3083	sulfuric ester hydrolase activity
IMX21_RS23380	COG1061	Type III restriction enzyme res subunit
IMX21_RS23385	COG1187	pseudouridine synthase activity
IMX21_RS23390	COG2814	Major facilitator Superfamily
IMX21_RS23400	COG4172	Belongs to the ABC transporter superfamily
IMX21_RS23405	COG4239	(ABC) transporter, permease
IMX21_RS23410	COG4174	ABC transporter (Permease)
IMX21_RS23415	COG4166	transmembrane transport
IMX21_RS23420	COG2200	EAL domain
IMX21_RS23425	COG0791	NLP P60 protein
IMX21_RS23430	COG0671	phosphoesterase, PA-phosphatase related
IMX21_RS23435	COG0523	cobalamin synthesis protein
IMX21_RS23440	COG0246	Mannitol dehydrogenase
IMX21_RS23455	COG2814	Major facilitator Superfamily
IMX21_RS23460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS23460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS23465	COG1105	Belongs to the carbohydrate kinase PfkB family
IMX21_RS23470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX21_RS23470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX21_RS23470	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IMX21_RS23475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX21_RS23480	COG2313	pseudouridylate synthase activity
IMX21_RS23485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMX21_RS23490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMX21_RS23500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMX21_RS23505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX21_RS23505	COG1522	sequence-specific DNA binding
IMX21_RS23515	COG2855	membrane
IMX21_RS23520	COG0583	DNA-binding transcription factor activity
IMX21_RS23525	COG0833	amino acid
IMX21_RS23530	COG4771	TonB-dependent receptor
IMX21_RS23535	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IMX21_RS23545	COG2311	Membrane
IMX21_RS23550	COG1609	Transcriptional regulator
IMX21_RS23555	COG1879	ABC-type sugar transport system periplasmic component
IMX21_RS23560	COG1129	ABC transporter
IMX21_RS23565	COG4211	Belongs to the binding-protein-dependent transport system permease family
IMX21_RS23570	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IMX21_RS23570	COG0167	dihydroorotate dehydrogenase activity
IMX21_RS23575	COG0493	'glutamate synthase
IMX21_RS23585	COG2949	membrane
IMX21_RS23595	COG1346	cytolysis
IMX21_RS23610	COG2271	Major facilitator Superfamily
IMX21_RS23625	COG0625	glutathione transferase activity
IMX21_RS23630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMX21_RS23635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMX21_RS23645	COG1538	Outer membrane efflux protein
IMX21_RS23650	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS23655	COG0586	Pfam SNARE associated Golgi protein
IMX21_RS23665	COG1686	Belongs to the peptidase S11 family
IMX21_RS23670	COG0277	FAD linked oxidase domain protein
IMX21_RS23675	COG1472	Belongs to the glycosyl hydrolase 3 family
IMX21_RS23680	COG1732	Glycine betaine
IMX21_RS23685	COG1174	glycine betaine transport
IMX21_RS23690	COG1125	glycine betaine transport
IMX21_RS23695	COG1174	glycine betaine transport
IMX21_RS23705	COG0789	Transcriptional regulator
IMX21_RS23710	COG0582	viral genome integration into host DNA
IMX21_RS23935	COG3772	lysozyme
IMX21_RS24075	COG5301	cellulose 1,4-beta-cellobiosidase activity
IMX21_RS24090	COG3275	phosphorelay sensor kinase activity
IMX21_RS24095	COG3279	Response regulator of the LytR AlgR family
IMX21_RS24100	COG4807	Protein conserved in bacteria
IMX21_RS24105	COG4808	Protein conserved in bacteria
IMX21_RS24110	COG4715	Zinc finger, swim domain protein
IMX21_RS24115	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IMX21_RS24120	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IMX21_RS24125	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IMX21_RS24130	COG0714	Associated with various cellular activities
IMX21_RS24140	COG3831	ATPase activity
IMX21_RS24160	COG0489	protein tyrosine kinase activity
IMX21_RS24170	COG3539	Fimbrial protein
IMX21_RS24175	COG3121	Chaperone
IMX21_RS24180	COG3188	usher protein
IMX21_RS24185	COG3539	Fimbrial protein
IMX21_RS24190	COG5455	response to cobalt ion
IMX21_RS24195	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IMX21_RS24225	COG0351	phosphomethylpyrimidine kinase
IMX21_RS24230	COG3757	hydrolase, family 25
IMX21_RS24235	COG2188	Transcriptional regulator
IMX21_RS24240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX21_RS24245	COG1397	ADP-ribosylglycohydrolase
IMX21_RS24250	COG2211	Major facilitator Superfamily
IMX21_RS24255	COG1830	Aldolase
IMX21_RS24270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX21_RS24275	COG3414	Phosphotransferase system galactitol-specific IIB component
IMX21_RS24280	COG3775	system Galactitol-specific IIC component
IMX21_RS24285	COG1063	alcohol dehydrogenase
IMX21_RS24305	COG0826	peptidase U32
IMX21_RS24310	COG3422	double-strand break repair
IMX21_RS24315	COG0745	RESPONSE REGULATOR receiver
IMX21_RS24320	COG2205	protein histidine kinase activity
IMX21_RS24335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMX21_RS24360	COG4245	von Willebrand factor, type A
IMX21_RS24365	COG0631	protein serine/threonine phosphatase activity
IMX21_RS24370	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
IMX21_RS24375	COG0443	Heat shock 70 kDa protein
IMX21_RS24380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IMX21_RS24390	COG0572	uridine kinase
IMX21_RS24400	COG2982	Protein involved in outer membrane biogenesis
IMX21_RS24415	COG1253	flavin adenine dinucleotide binding
IMX21_RS24425	COG1596	polysaccharide export
IMX21_RS24430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMX21_RS24435	COG3206	protein involved in exopolysaccharide biosynthesis
IMX21_RS24435	COG0489	protein tyrosine kinase activity
IMX21_RS24440	COG0463	Glycosyl transferase, family 2
IMX21_RS24445	COG1045	serine acetyltransferase
IMX21_RS24450	COG0438	transferase activity, transferring glycosyl groups
IMX21_RS24460	COG1216	Glycosyl transferase, family 2
IMX21_RS24465	COG0110	maltose O-acetyltransferase activity
IMX21_RS24470	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IMX21_RS24475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMX21_RS24480	COG1051	belongs to the nudix hydrolase family
IMX21_RS24485	COG0297	glycogen (starch) synthase activity
IMX21_RS24490	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IMX21_RS24490	COG0662	Cupin 2, conserved barrel domain protein
IMX21_RS24495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMX21_RS24500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMX21_RS24505	COG2244	polysaccharide biosynthetic process
IMX21_RS24510	COG2327	Polysaccharide pyruvyl transferase
IMX21_RS24515	COG0438	transferase activity, transferring glycosyl groups
IMX21_RS24525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMX21_RS24530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMX21_RS24555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMX21_RS24565	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IMX21_RS24570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMX21_RS24575	COG1051	belongs to the nudix hydrolase family
IMX21_RS24580	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IMX21_RS24580	COG0662	Cupin 2, conserved barrel domain protein
IMX21_RS24585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMX21_RS24595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IMX21_RS24600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMX21_RS24625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMX21_RS24630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IMX21_RS24630	COG0131	Imidazoleglycerol-phosphate dehydratase
IMX21_RS24640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMX21_RS24655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMX21_RS24660	COG0583	DNA-binding transcription factor activity
IMX21_RS24670	COG0531	amino acid
IMX21_RS24675	COG2391	methyltransferase activity
IMX21_RS24680	COG0425	Belongs to the sulfur carrier protein TusA family
IMX21_RS24685	COG2925	Exonuclease
IMX21_RS24690	COG1686	Belongs to the peptidase S11 family
IMX21_RS24700	COG1289	transmembrane transporter activity
IMX21_RS24710	COG4917	ethanolamine utilization protein
IMX21_RS24745	COG2003	Belongs to the UPF0758 family
IMX21_RS24790	COG4771	TonB-dependent receptor
IMX21_RS24795	COG4372	Transposase
IMX21_RS24800	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS24810	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
IMX21_RS24825	COG1376	ErfK ybiS ycfS ynhG family protein
IMX21_RS24835	COG0583	DNA-binding transcription factor activity
IMX21_RS24840	COG0583	DNA-binding transcription factor activity
IMX21_RS24860	COG0217	transcriptional regulatory protein
IMX21_RS24865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMX21_RS24870	COG0477	Major facilitator Superfamily
IMX21_RS24910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX21_RS24955	COG1846	Transcriptional regulator
IMX21_RS25000	COG1403	HNH endonuclease
IMX21_RS25005	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IMX21_RS25060	COG3772	lysozyme
IMX21_RS25090	COG4220	transposase activity
IMX21_RS25165	COG2032	superoxide dismutase activity
IMX21_RS25180	COG5301	cellulose 1,4-beta-cellobiosidase activity
IMX21_RS25200	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IMX21_RS25205	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IMX21_RS25210	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
IMX21_RS25215	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IMX21_RS25220	COG1999	signal sequence binding
IMX21_RS25225	COG1773	rubredoxin
IMX21_RS25230	COG1271	oxidase subunit
IMX21_RS25235	COG1294	oxidase, subunit
IMX21_RS25250	COG0489	protein tyrosine kinase activity
IMX21_RS25250	COG3206	protein involved in exopolysaccharide biosynthesis
IMX21_RS25255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMX21_RS25260	COG1596	polysaccharide export
IMX21_RS25265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMX21_RS25285	COG1278	Cold shock
IMX21_RS25290	COG1278	Cold shock
IMX21_RS25310	COG0348	domain, Protein
IMX21_RS25315	COG0784	Response regulator, receiver
IMX21_RS25315	COG2198	Histidine kinase
IMX21_RS25315	COG2205	protein histidine kinase activity
IMX21_RS25320	COG1879	ABC-type sugar transport system periplasmic component
IMX21_RS25325	COG0745	RESPONSE REGULATOR receiver
IMX21_RS25330	COG3005	denitrification pathway
IMX21_RS25335	COG0243	molybdopterin cofactor binding
IMX21_RS25375	COG0582	viral genome integration into host DNA
IMX21_RS25515	COG0305	Participates in initiation and elongation during chromosome replication
IMX21_RS25635	COG3772	lysozyme
IMX21_RS25785	COG3111	PFAM Bacterial OB fold (BOF) protein
IMX21_RS25820	COG3561	AntA/AntB antirepressor
IMX21_RS25825	COG3729	General stress protein
IMX21_RS25830	COG2233	PERMEase
IMX21_RS25865	COG1309	transcriptional regulator
IMX21_RS25870	COG0506	proline dehydrogenase activity
IMX21_RS25870	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IMX21_RS25870	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IMX21_RS25880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMX21_RS25895	COG2822	iron ion transport
IMX21_RS25900	COG2837	iron assimilation
IMX21_RS25905	COG1702	phosphate starvation-inducible protein PhoH
IMX21_RS25910	COG3658	cytochrome
IMX21_RS25915	COG1215	transferase activity, transferring glycosyl groups
IMX21_RS25920	COG0726	polysaccharide deacetylase
IMX21_RS25920	COG1649	PFAM Uncharacterised BCR, COG1649
IMX21_RS25925	COG0457	Tetratricopeptide repeat
IMX21_RS25930	COG3706	GGDEF domain
IMX21_RS25935	COG2200	EAL domain
IMX21_RS25945	COG3710	Transcriptional regulator
IMX21_RS25950	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS25955	COG3121	Chaperone
IMX21_RS25965	COG3188	usher protein
IMX21_RS25975	COG3539	Fimbrial protein
IMX21_RS25985	COG3210	domain, Protein
IMX21_RS25990	COG2831	hemolysin activation secretion protein
IMX21_RS25995	COG0736	holo-[acyl-carrier-protein] synthase activity
IMX21_RS26005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMX21_RS26015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMX21_RS26020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMX21_RS26070	COG0582	viral genome integration into host DNA
IMX21_RS26095	COG4983	Phage plasmid primase, P4 family domain protein
IMX21_RS26120	COG4372	Transposase
IMX21_RS26125	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS26160	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IMX21_RS26165	COG2194	sulfuric ester hydrolase activity
IMX21_RS26175	COG0829	nickel cation binding
IMX21_RS26220	COG0254	rRNA binding
IMX21_RS26250	COG3436	PFAM IS66 Orf2 family protein
IMX21_RS26255	COG4372	Transposase
IMX21_RS26290	COG1358	cellular component organization or biogenesis
IMX21_RS26350	COG4771	TonB-dependent receptor
IMX21_RS26435	COG2831	hemolysin activation secretion protein
IMX21_RS26445	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IMX21_RS26450	COG3969	phosphoadenosine phosphosulfate
IMX21_RS26455	COG1475	DNA binding
IMX21_RS26495	COG3468	outer membrane autotransporter barrel domain protein
IMX21_RS26525	COG2003	Belongs to the UPF0758 family
IMX21_RS26575	COG3381	protein complex oligomerization
IMX21_RS26585	COG1462	curli production assembly transport component CsgG
IMX21_RS26600	COG2197	response regulator
IMX21_RS26625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IMX21_RS26630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMX21_RS26645	COG2943	transferase activity, transferring hexosyl groups
IMX21_RS26650	COG5645	(Lipo)protein
IMX21_RS26665	COG1560	Kdo2-lipid A biosynthetic process
IMX21_RS26675	COG2353	YceI-like domain
IMX21_RS26680	COG3038	cytochrome b561
IMX21_RS26715	COG2999	glutathione oxidoreductase activity
IMX21_RS26725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMX21_RS26735	COG0673	inositol 2-dehydrogenase activity
IMX21_RS26740	COG0728	peptidoglycan biosynthetic process
IMX21_RS26745	COG3418	PFAM FlgN family protein
IMX21_RS26750	COG2747	anti-sigma28 factor FlgM
IMX21_RS26755	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IMX21_RS26760	COG1815	bacterial-type flagellum-dependent cell motility
IMX21_RS26765	COG1558	bacterial-type flagellum-dependent cell motility
IMX21_RS26770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IMX21_RS26775	COG1749	Flagellar hook protein flgE
IMX21_RS26780	COG4787	bacterial-type flagellum-dependent cell motility
IMX21_RS26785	COG4786	Flagellar basal body rod
IMX21_RS26800	COG3951	Flagellar rod assembly protein muramidase FlgJ
IMX21_RS26800	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMX21_RS26805	COG1256	bacterial-type flagellum assembly
IMX21_RS26810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMX21_RS26815	COG1530	ribonuclease E activity
IMX21_RS26820	COG0564	pseudouridine synthase activity
IMX21_RS26825	COG0424	maF-like protein
IMX21_RS26830	COG1399	metal-binding, possibly nucleic acid-binding protein
IMX21_RS26850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IMX21_RS26855	COG1028	Short-chain dehydrogenase reductase Sdr
IMX21_RS26865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMX21_RS26870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMX21_RS26875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMX21_RS26885	COG0470	DNA polymerase III
IMX21_RS26890	COG0084	hydrolase, TatD family'
IMX21_RS26895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX21_RS26895	COG1263	PTS System
IMX21_RS26900	COG4773	Receptor
IMX21_RS26910	COG0537	adenosine 5'-monophosphoramidase activity
IMX21_RS26915	COG5633	Lipoprotein
IMX21_RS26920	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
IMX21_RS26925	COG0510	thiamine kinase activity
IMX21_RS26940	COG1252	NADH dehydrogenase
IMX21_RS26945	COG3134	Outer membrane lipoprotein
IMX21_RS26950	COG1309	transcriptional regulator
IMX21_RS26960	COG1388	LysM domain
IMX21_RS26960	COG1376	ErfK ybiS ycfS ynhG family protein
IMX21_RS26965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMX21_RS26970	COG4763	Acyl-transferase
IMX21_RS26975	COG4591	ABC-type transport system involved in lipoprotein release permease component
IMX21_RS26980	COG1136	(ABC) transporter
IMX21_RS26985	COG4591	ABC-type transport system involved in lipoprotein release permease component
IMX21_RS26995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IMX21_RS27000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IMX21_RS27005	COG1177	transmembrane transport
IMX21_RS27010	COG0582	viral genome integration into host DNA
IMX21_RS27040	COG4197	protein conserved in bacteria, prophage-related
IMX21_RS27060	COG1846	Transcriptional regulator
IMX21_RS27115	COG1403	HNH endonuclease
IMX21_RS27120	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IMX21_RS27125	COG0484	heat shock protein binding
IMX21_RS27165	COG3772	lysozyme
IMX21_RS27240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMX21_RS27270	COG1560	Kdo2-lipid A biosynthetic process
IMX21_RS27275	COG2194	sulfuric ester hydrolase activity
IMX21_RS27280	COG0297	glycogen (starch) synthase activity
IMX21_RS27285	COG0726	polysaccharide deacetylase
IMX21_RS27305	COG3468	outer membrane autotransporter barrel domain protein
IMX21_RS27385	COG1525	nuclease
IMX21_RS27395	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IMX21_RS27480	COG1475	DNA binding
IMX21_RS27655	COG2274	protein secretion by the type I secretion system