locus-tag	class	description
EC958_RS00010	COG0460	homoserine dehydrogenase
EC958_RS00010	COG0527	aspartate kinase activity
EC958_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EC958_RS00040	COG1115	amino acid carrier protein
EC958_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
EC958_RS00055	COG1584	GPR1 FUN34 yaaH family protein
EC958_RS00060	COG4735	regulation of single-species biofilm formation
EC958_RS00090	COG3119	arylsulfatase activity
EC958_RS00105	COG0583	DNA-binding transcription factor activity
EC958_RS00130	COG0196	riboflavin kinase activity
EC958_RS00145	COG1047	Peptidyl-prolyl cis-trans
EC958_RS00180	COG0505	Belongs to the CarA family
EC958_RS00185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EC958_RS00240	COG0644	oxidoreductase
EC958_RS00245	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EC958_RS00250	COG2271	Major facilitator Superfamily
EC958_RS00265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EC958_RS00295	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EC958_RS00300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC958_RS00310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EC958_RS00315	COG0564	pseudouridine synthase activity
EC958_RS00325	COG0417	DNA replication proofreading
EC958_RS00330	COG0235	Class ii aldolase
EC958_RS00345	COG4977	sequence-specific DNA binding
EC958_RS00350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS00355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC958_RS00360	COG3181	Tripartite tricarboxylate transporter family receptor
EC958_RS00375	COG0586	Pfam SNARE associated Golgi protein
EC958_RS00385	COG1178	ABC-type Fe3 transport system permease component
EC958_RS00390	COG4143	(ABC) transporter
EC958_RS00430	COG0583	DNA-binding transcription factor activity
EC958_RS00435	COG0028	Belongs to the TPP enzyme family
EC958_RS00440	COG0440	acetolactate synthase activity
EC958_RS00450	COG1609	Transcriptional regulator
EC958_RS00465	COG3116	cell division
EC958_RS00470	COG0768	penicillin binding
EC958_RS00475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EC958_RS00480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EC958_RS00495	COG0772	Belongs to the SEDS family
EC958_RS00510	COG1181	Belongs to the D-alanine--D-alanine ligase family
EC958_RS00515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EC958_RS00520	COG0849	cell division
EC958_RS00525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EC958_RS00545	COG0494	nUDIX hydrolase
EC958_RS00560	COG0237	dephospho-CoA kinase activity
EC958_RS00570	COG1459	type II secretion system
EC958_RS00580	COG4969	Belongs to the N-Me-Phe pilin family
EC958_RS00590	COG0157	Belongs to the NadC ModD family
EC958_RS00595	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC958_RS00600	COG3725	Membrane protein required for beta-lactamase induction
EC958_RS00605	COG1113	amino acid transport
EC958_RS00610	COG3157	Type VI secretion system effector, Hcp
EC958_RS00650	COG2186	Transcriptional regulator
EC958_RS00655	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EC958_RS00660	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC958_RS00665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC958_RS00670	COG3064	Membrane
EC958_RS00670	COG3064	Membrane
EC958_RS00675	COG1049	propionate catabolic process, 2-methylcitrate cycle
EC958_RS00700	COG2132	Multicopper oxidase
EC958_RS00705	COG4993	Dehydrogenase
EC958_RS00710	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EC958_RS00715	COG0288	reversible hydration of carbon dioxide
EC958_RS00720	COG1131	(ABC) transporter
EC958_RS00725	COG0842	Transport permease protein
EC958_RS00730	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS00735	COG0726	polysaccharide deacetylase
EC958_RS00745	COG5464	transposase or invertase
EC958_RS00750	COG5464	transposase or invertase
EC958_RS00755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EC958_RS00765	COG3539	Fimbrial protein
EC958_RS00770	COG3539	Fimbrial protein
EC958_RS00775	COG3539	Fimbrial protein
EC958_RS00780	COG3539	Fimbrial protein
EC958_RS00785	COG3188	usher protein
EC958_RS00790	COG3121	Chaperone
EC958_RS00795	COG3539	Fimbrial protein
EC958_RS00800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EC958_RS00805	COG0617	tRNA 3'-terminal CCA addition
EC958_RS00810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EC958_RS00815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EC958_RS00825	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EC958_RS00830	COG1643	Atp-dependent helicase
EC958_RS00835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EC958_RS00845	COG3121	Chaperone
EC958_RS00860	COG4774	siderophore transport
EC958_RS00865	COG1120	ATPase activity
EC958_RS00870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EC958_RS00875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC958_RS00895	COG2860	membrane
EC958_RS00900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EC958_RS00915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC958_RS00920	COG3835	regulator
EC958_RS00940	COG0024	Methionine aminopeptidase
EC958_RS00965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EC958_RS00970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EC958_RS00975	COG0575	Belongs to the CDS family
EC958_RS00980	COG0750	zinc metalloprotease
EC958_RS00990	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EC958_RS00995	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC958_RS01020	COG0587	DNA-directed DNA polymerase activity
EC958_RS01030	COG1982	Orn Lys Arg decarboxylase major
EC958_RS01035	COG0346	lactoylglutathione lyase activity
EC958_RS01040	COG0037	tRNA processing
EC958_RS01045	COG4568	rho-dependent transcription termination
EC958_RS01055	COG4681	YaeQ
EC958_RS01060	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EC958_RS01065	COG3015	lipoprotein NlpE involved in copper resistance
EC958_RS01080	COG3436	PFAM IS66 Orf2 family protein
EC958_RS01085	COG4372	Transposase
EC958_RS01100	COG1720	tRNA m6t6A37 methyltransferase activity
EC958_RS01110	COG1464	Belongs to the NlpA lipoprotein family
EC958_RS01115	COG2011	ABC-type metal ion transport system permease component
EC958_RS01120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EC958_RS01125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EC958_RS01160	COG0656	L-ascorbic acid biosynthetic process
EC958_RS01165	COG0583	DNA-binding transcription factor activity
EC958_RS01175	COG2226	methyltransferase
EC958_RS01180	COG1388	LysM domain
EC958_RS01180	COG0741	lytic transglycosylase activity
EC958_RS01190	COG2226	methyltransferase
EC958_RS01200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC958_RS01210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC958_RS01220	COG1960	acyl-CoA dehydrogenase activity
EC958_RS01230	COG0121	glutamine amidotransferase
EC958_RS01235	COG3034	peptidoglycan biosynthetic process
EC958_RS01240	COG0791	NLP P60 protein
EC958_RS01245	COG1943	Transposase
EC958_RS01265	COG1987	bacterial-type flagellum assembly
EC958_RS01290	COG1677	Flagellar hook-basal body complex protein FliE
EC958_RS01300	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EC958_RS01320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EC958_RS01360	COG1815	bacterial-type flagellum-dependent cell motility
EC958_RS01365	COG1558	bacterial-type flagellum-dependent cell motility
EC958_RS01375	COG1749	Flagellar hook protein flgE
EC958_RS01380	COG4787	bacterial-type flagellum-dependent cell motility
EC958_RS01385	COG4786	Flagellar basal body rod
EC958_RS01410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EC958_RS01425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EC958_RS01430	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EC958_RS01455	COG1191	sigma factor activity
EC958_RS01460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EC958_RS01475	COG0454	-acetyltransferase
EC958_RS01480	COG1690	Belongs to the RtcB family
EC958_RS01485	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EC958_RS01490	COG2195	Cleaves the N-terminal amino acid of tripeptides
EC958_RS01510	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC958_RS01535	COG0732	type I restriction modification DNA specificity domain
EC958_RS01575	COG3477	response to acidic pH
EC958_RS01580	COG0727	PFAM Uncharacterised protein family (UPF0153)
EC958_RS01630	COG1902	pentaerythritol trinitrate reductase activity
EC958_RS01635	COG1073	alpha beta
EC958_RS01640	COG0583	DNA-binding transcription factor activity
EC958_RS01650	COG0667	Aldo Keto reductase
EC958_RS01655	COG0656	L-ascorbic acid biosynthetic process
EC958_RS01660	COG1388	LysM domain
EC958_RS01660	COG2373	Large extracellular alpha-helical protein
EC958_RS01660	COG4932	domain protein
EC958_RS01665	COG2207	Transcriptional regulator
EC958_RS01665	COG3708	Transcriptional regulator
EC958_RS01670	COG0656	L-ascorbic acid biosynthetic process
EC958_RS01675	COG3059	membrane
EC958_RS01685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC958_RS01690	COG2207	Transcriptional regulator
EC958_RS01695	COG0247	lactate metabolic process
EC958_RS01700	COG1139	Iron-sulfur cluster binding protein
EC958_RS01705	COG1556	Lactate utilization protein
EC958_RS01730	COG2200	EAL domain
EC958_RS01730	COG2771	luxR family
EC958_RS01735	COG0582	viral genome integration into host DNA
EC958_RS01750	COG1012	belongs to the aldehyde dehydrogenase family
EC958_RS01760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EC958_RS01770	COG2771	luxR family
EC958_RS01770	COG2200	EAL domain
EC958_RS01775	COG0583	DNA-binding transcription factor activity
EC958_RS01785	COG0666	response to abiotic stimulus
EC958_RS01795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EC958_RS01800	COG1304	FMN binding
EC958_RS01805	COG0549	Belongs to the carbamate kinase family
EC958_RS01810	COG0402	S-adenosylhomocysteine deaminase activity
EC958_RS01815	COG1064	alcohol dehydrogenase
EC958_RS01820	COG1280	lysine exporter protein (LysE YggA)
EC958_RS01830	COG3829	transcription factor binding
EC958_RS01835	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EC958_RS01840	COG0372	Belongs to the citrate synthase family
EC958_RS01845	COG2079	MmgE PrpD family protein
EC958_RS01850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EC958_RS01855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EC958_RS01860	COG0402	S-adenosylhomocysteine deaminase activity
EC958_RS01865	COG0110	maltose O-acetyltransferase activity
EC958_RS01870	COG2223	nitrite transmembrane transporter activity
EC958_RS01880	COG1609	Transcriptional regulator
EC958_RS01885	COG1414	Transcriptional regulator
EC958_RS01915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EC958_RS01920	COG2814	Major facilitator Superfamily
EC958_RS01925	COG3122	Protein conserved in bacteria
EC958_RS01945	COG4521	taurine ABC transporter
EC958_RS01955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC958_RS01960	COG2175	clavaminate synthase activity
EC958_RS01965	COG0113	porphobilinogen synthase activity
EC958_RS01970	COG3468	outer membrane autotransporter barrel domain protein
EC958_RS01975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC958_RS01980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EC958_RS01990	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EC958_RS02010	COG1181	Belongs to the D-alanine--D-alanine ligase family
EC958_RS02020	COG1785	Belongs to the alkaline phosphatase family
EC958_RS02030	COG3706	GGDEF domain
EC958_RS02035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EC958_RS02060	COG4126	flavin adenine dinucleotide binding
EC958_RS02080	COG1940	carbohydrate kinase activity
EC958_RS02085	COG2814	Major facilitator Superfamily
EC958_RS02090	COG0419	ATPase involved in DNA repair
EC958_RS02095	COG0420	3'-5' exonuclease activity
EC958_RS02100	COG0745	RESPONSE REGULATOR receiver
EC958_RS02105	COG5002	protein histidine kinase activity
EC958_RS02110	COG1114	Component of the transport system for branched-chain amino acids
EC958_RS02115	COG1113	amino acid transport
EC958_RS02120	COG0366	Alpha amylase catalytic
EC958_RS02140	COG1862	Preprotein translocase
EC958_RS02145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EC958_RS02150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EC958_RS02155	COG1403	HNH endonuclease
EC958_RS02160	COG3248	Nucleoside-binding outer membrane protein
EC958_RS02165	COG4238	major outer membrane lipoprotein
EC958_RS02175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC958_RS02175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC958_RS02190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EC958_RS02195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EC958_RS02200	COG0667	Aldo Keto reductase
EC958_RS02210	COG0142	geranyltranstransferase activity
EC958_RS02225	COG0693	protein deglycase activity
EC958_RS02230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EC958_RS02240	COG2814	Major facilitator Superfamily
EC958_RS02250	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EC958_RS02255	COG1845	cytochrome c oxidase, subunit III
EC958_RS02260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EC958_RS02265	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EC958_RS02270	COG2223	nitrite transmembrane transporter activity
EC958_RS02275	COG3056	Lipoprotein
EC958_RS02280	COG0271	Belongs to the BolA IbaG family
EC958_RS02305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EC958_RS02310	COG0776	regulation of translation
EC958_RS02315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC958_RS02320	COG1555	photosystem II stabilization
EC958_RS02325	COG0824	Thioesterase
EC958_RS02335	COG4533	DNA binding
EC958_RS02345	COG1522	sequence-specific DNA binding
EC958_RS02350	COG1132	(ABC) transporter
EC958_RS02355	COG1132	(ABC) transporter
EC958_RS02360	COG0347	Belongs to the P(II) protein family
EC958_RS02365	COG0004	ammonium transporteR
EC958_RS02370	COG1946	Acyl-CoA thioesterase
EC958_RS02375	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EC958_RS02380	COG3695	enzyme binding
EC958_RS02385	COG5507	3-demethylubiquinone-9 3-methyltransferase
EC958_RS02390	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EC958_RS02400	COG0110	maltose O-acetyltransferase activity
EC958_RS02415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC958_RS02420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC958_RS02430	COG1196	nuclear chromosome segregation
EC958_RS02430	COG3264	Mechanosensitive ion channel
EC958_RS02440	COG3923	Primosomal replication protein n
EC958_RS02445	COG2832	Protein of unknown function (DUF454)
EC958_RS02455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EC958_RS02490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS02495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC958_RS02495	COG4651	solute:proton antiporter activity
EC958_RS02500	COG2223	nitrite transmembrane transporter activity
EC958_RS02505	COG0737	Belongs to the 5'-nucleotidase family
EC958_RS02520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EC958_RS02525	COG3735	TraB family
EC958_RS02530	COG3549	Plasmid maintenance system killer
EC958_RS02535	COG3093	addiction module antidote protein HigA
EC958_RS02540	COG2217	Heavy metal translocating P-type atpase
EC958_RS02545	COG2066	Belongs to the glutaminase family
EC958_RS02550	COG0531	amino acid
EC958_RS02555	COG0789	Transcriptional regulator
EC958_RS02570	COG1585	Membrane protein implicated in regulation of membrane protease activity
EC958_RS02575	COG0330	HflC and HflK could
EC958_RS02580	COG4619	ABC transporter
EC958_RS02585	COG0390	transport system, permease component
EC958_RS02590	COG3118	belongs to the thioredoxin family
EC958_RS02595	COG0300	oxidoreductase activity
EC958_RS02600	COG2755	lipolytic protein G-D-S-L family
EC958_RS02605	COG4181	ATPase activity
EC958_RS02610	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EC958_RS02615	COG3157	Type VI secretion system effector, Hcp
EC958_RS02655	COG3960	tartronate-semialdehyde synthase activity
EC958_RS02660	COG3622	Belongs to the hyi family
EC958_RS02665	COG2084	Dehydrogenase
EC958_RS02670	COG1953	Uracil, thiamine, allantoin
EC958_RS02680	COG2233	PERMEase
EC958_RS02685	COG1929	Belongs to the glycerate kinase type-1 family
EC958_RS02690	COG3257	ureidoglycine aminohydrolase activity
EC958_RS02695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EC958_RS02700	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EC958_RS02705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EC958_RS02710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EC958_RS02720	COG0549	Belongs to the carbamate kinase family
EC958_RS02725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EC958_RS02730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EC958_RS02745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EC958_RS02755	COG1988	membrane-bound metal-dependent
EC958_RS02760	COG2501	S4 domain
EC958_RS02795	COG0500	methyltransferase
EC958_RS02800	COG4571	Outer membrane protease
EC958_RS02810	COG4783	chaperone-mediated protein folding
EC958_RS02815	COG1215	transferase activity, transferring glycosyl groups
EC958_RS02820	COG5002	protein histidine kinase activity
EC958_RS02825	COG0745	RESPONSE REGULATOR receiver
EC958_RS02830	COG1538	Outer membrane efflux protein
EC958_RS02835	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC958_RS02840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC958_RS02845	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC958_RS02850	COG1113	amino acid transport
EC958_RS02855	COG0668	transmembrane transport
EC958_RS02860	COG0778	Nitroreductase
EC958_RS02865	COG2315	Protein conserved in bacteria
EC958_RS02900	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS02910	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC958_RS02915	COG1129	ABC transporter
EC958_RS02925	COG1879	ABC-type sugar transport system periplasmic component
EC958_RS02930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EC958_RS02935	COG2390	Transcriptional regulator
EC958_RS02940	COG3959	Transketolase, thiamine diphosphate binding domain
EC958_RS02945	COG3958	Transketolase
EC958_RS02960	COG4771	TonB-dependent receptor
EC958_RS02965	COG2382	esterase
EC958_RS02970	COG3251	PFAM MbtH domain protein
EC958_RS02975	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EC958_RS02975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EC958_RS02980	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EC958_RS02985	COG1120	ATPase activity
EC958_RS02990	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC958_RS02995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC958_RS03005	COG4592	Periplasmic binding protein
EC958_RS03010	COG1169	isochorismate synthase
EC958_RS03015	COG1021	2,3-dihydroxybenzoate-AMP ligase
EC958_RS03020	COG1535	isochorismatase
EC958_RS03020	COG3433	isochorismatase activity
EC958_RS03025	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS03030	COG2050	protein possibly involved in aromatic compounds catabolism
EC958_RS03035	COG1966	Carbon starvation protein
EC958_RS03040	COG2879	small protein
EC958_RS03045	COG0371	Dehydrogenase
EC958_RS03050	COG0436	Aminotransferase
EC958_RS03055	COG1475	DNA binding
EC958_RS03060	COG3969	phosphoadenosine phosphosulfate
EC958_RS03065	COG0583	DNA-binding transcription factor activity
EC958_RS03070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EC958_RS03075	COG0450	alkyl hydroperoxide reductase
EC958_RS03080	COG3634	alkyl hydroperoxide reductase activity
EC958_RS03085	COG0589	response to stress
EC958_RS03090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EC958_RS03095	COG3719	Belongs to the RNase T2 family
EC958_RS03100	COG0471	metal ion transport
EC958_RS03115	COG3051	citrate lyase alpha subunit
EC958_RS03120	COG2301	Belongs to the HpcH HpaI aldolase family
EC958_RS03130	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EC958_RS03135	COG3290	protein histidine kinase activity
EC958_RS03140	COG4565	transcriptional regulatory protein
EC958_RS03145	COG3069	C4-dicarboxylate transmembrane transporter activity
EC958_RS03165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC958_RS03170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EC958_RS03200	COG1686	Belongs to the peptidase S11 family
EC958_RS03205	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EC958_RS03210	COG0772	Belongs to the SEDS family
EC958_RS03215	COG0768	penicillin binding
EC958_RS03225	COG0799	negative regulation of ribosome biogenesis
EC958_RS03230	COG0406	alpha-ribazole phosphatase activity
EC958_RS03240	COG1466	dna polymerase III delta subunit
EC958_RS03255	COG2888	peptidyl-tyrosine sulfation
EC958_RS03265	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EC958_RS03275	COG2214	Heat shock protein DnaJ domain protein
EC958_RS03280	COG0443	Heat shock 70 kDa protein
EC958_RS03290	COG1126	abc transporter atp-binding protein
EC958_RS03295	COG0765	amino acid transport
EC958_RS03300	COG0765	amino acid transport
EC958_RS03305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC958_RS03315	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EC958_RS03320	COG4535	Mg2 and Co2 transporter CorC
EC958_RS03330	COG1702	phosphate starvation-inducible protein PhoH
EC958_RS03340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC958_RS03385	COG0367	asparagine synthase
EC958_RS03390	COG0647	UMP catabolic process
EC958_RS03395	COG1846	Transcriptional regulator
EC958_RS03395	COG1940	carbohydrate kinase activity
EC958_RS03400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EC958_RS03410	COG1263	PTS System
EC958_RS03410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS03410	COG2190	(PTS) system
EC958_RS03430	COG0861	Integral membrane protein TerC family
EC958_RS03435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC958_RS03445	COG3395	kinase activity
EC958_RS03450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EC958_RS03455	COG1349	DNA-binding transcription factor activity
EC958_RS03475	COG0735	belongs to the Fur family
EC958_RS03490	COG0716	FMN binding
EC958_RS03500	COG0596	Alpha beta hydrolase
EC958_RS03505	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EC958_RS03510	COG0033	Phosphoglucomutase
EC958_RS03515	COG0531	amino acid
EC958_RS03520	COG1982	Orn Lys Arg decarboxylase major
EC958_RS03530	COG0745	RESPONSE REGULATOR receiver
EC958_RS03535	COG2205	protein histidine kinase activity
EC958_RS03565	COG3272	Protein of unknown function (DUF1722)
EC958_RS03570	COG0415	Belongs to the DNA photolyase family
EC958_RS03580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EC958_RS03585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EC958_RS03590	COG1984	allophanate hydrolase subunit 2
EC958_RS03595	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EC958_RS03605	COG3180	Ammonia monooxygenase
EC958_RS03610	COG2186	Transcriptional regulator
EC958_RS03615	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC958_RS03615	COG0473	3-isopropylmalate dehydrogenase activity
EC958_RS03620	COG1063	alcohol dehydrogenase
EC958_RS03625	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS03635	COG2721	sulfolactate sulfo-lyase activity
EC958_RS03640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EC958_RS03650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EC958_RS03655	COG0372	Belongs to the citrate synthase family
EC958_RS03665	COG2009	succinate dehydrogenase
EC958_RS03670	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EC958_RS03675	COG1053	succinate dehydrogenase
EC958_RS03680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EC958_RS03690	COG0567	Dehydrogenase, E1 component
EC958_RS03695	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC958_RS03705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EC958_RS03710	COG2188	Transcriptional regulator
EC958_RS03715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS03715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS03715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS03720	COG0383	alpha-mannosidase activity
EC958_RS03735	COG1271	oxidase subunit
EC958_RS03740	COG1294	oxidase, subunit
EC958_RS03745	COG4890	Cyd operon protein YbgT
EC958_RS03750	COG3790	cyd operon protein YbgE
EC958_RS03755	COG0824	Thioesterase
EC958_RS03760	COG0811	peptide transport
EC958_RS03765	COG0848	biopolymer transport protein
EC958_RS03770	COG3064	Membrane
EC958_RS03780	COG2885	chlorophyll binding
EC958_RS03785	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EC958_RS03825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EC958_RS03830	COG3201	nicotinamide mononucleotide transporter
EC958_RS03835	COG1230	cation diffusion facilitator family transporter
EC958_RS03850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EC958_RS03860	COG2017	converts alpha-aldose to the beta-anomer
EC958_RS03870	COG1085	galactose-1-phosphate uridylyltransferase
EC958_RS03875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EC958_RS03880	COG1119	ATPase activity
EC958_RS03890	COG2005	Transcriptional regulator
EC958_RS03890	COG3585	molybdate ion transport
EC958_RS03900	COG0725	ABC transporter, periplasmic molybdate-binding protein
EC958_RS03905	COG4149	molybdate abc transporter
EC958_RS03910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EC958_RS03915	COG0561	phosphatase activity
EC958_RS03925	COG0583	DNA-binding transcription factor activity
EC958_RS03930	COG2828	Protein conserved in bacteria
EC958_RS03935	COG0471	metal ion transport
EC958_RS03940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EC958_RS03945	COG4677	pectinesterase activity
EC958_RS03950	COG1881	PFAM PEBP family protein
EC958_RS03955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EC958_RS03970	COG2226	methyltransferase
EC958_RS03975	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EC958_RS03985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EC958_RS04000	COG0521	Mo-molybdopterin cofactor biosynthetic process
EC958_RS04010	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EC958_RS04015	COG0314	molybdopterin synthase activity
EC958_RS04020	COG0670	Belongs to the BI1 family
EC958_RS04025	COG0670	Belongs to the BI1 family
EC958_RS04030	COG0392	lysyltransferase activity
EC958_RS04035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC958_RS04040	COG3568	Endonuclease Exonuclease Phosphatase
EC958_RS04050	COG0842	Transport permease protein
EC958_RS04055	COG0842	Transport permease protein
EC958_RS04060	COG1131	(ABC) transporter
EC958_RS04070	COG1309	transcriptional regulator
EC958_RS04075	COG0513	Belongs to the DEAD box helicase family
EC958_RS04090	COG1199	ATP-dependent helicase activity
EC958_RS04095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EC958_RS04100	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EC958_RS04110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EC958_RS04115	COG3128	pkhd-type hydroxylase
EC958_RS04135	COG0668	transmembrane transport
EC958_RS04140	COG1126	abc transporter atp-binding protein
EC958_RS04145	COG0765	amino acid transport
EC958_RS04150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC958_RS04165	COG5006	permease, DMT superfamily
EC958_RS04170	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EC958_RS04175	COG2194	sulfuric ester hydrolase activity
EC958_RS04185	COG1321	iron dependent repressor
EC958_RS04190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EC958_RS04195	COG1376	ErfK ybiS ycfS ynhG family protein
EC958_RS04200	COG0488	(ABC) transporter
EC958_RS04205	COG0561	phosphatase activity
EC958_RS04210	COG1882	Formate acetyltransferase
EC958_RS04215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC958_RS04220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EC958_RS04225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EC958_RS04230	COG0303	'Molybdopterin
EC958_RS04235	COG1446	asparaginase
EC958_RS04260	COG2200	EAL domain
EC958_RS04265	COG2199	diguanylate cyclase activity
EC958_RS04280	COG2133	pyrroloquinoline quinone binding
EC958_RS04285	COG0625	glutathione transferase activity
EC958_RS04290	COG1686	Belongs to the peptidase S11 family
EC958_RS04295	COG1349	DNA-binding transcription factor activity
EC958_RS04300	COG0671	phosphoesterase, PA-phosphatase related
EC958_RS04305	COG2814	Major facilitator Superfamily
EC958_RS04315	COG0561	phosphatase activity
EC958_RS04320	COG0738	Major facilitator superfamily
EC958_RS04325	COG3226	Transcriptional regulator
EC958_RS04340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EC958_RS04350	COG0778	Nitroreductase
EC958_RS04370	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EC958_RS04375	COG3842	ATPase activity
EC958_RS04380	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC958_RS04385	COG1177	transmembrane transport
EC958_RS04400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC958_RS04405	COG4160	amino acid transport
EC958_RS04410	COG4215	(ABC) transporter
EC958_RS04415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC958_RS04420	COG1126	abc transporter atp-binding protein
EC958_RS04435	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC958_RS04440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC958_RS04445	COG0702	epimerase
EC958_RS04450	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EC958_RS04455	COG0028	Belongs to the TPP enzyme family
EC958_RS04460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC958_RS04465	COG1151	hydroxylamine reductase activity
EC958_RS04470	COG2431	L-lysine efflux transmembrane transporter activity
EC958_RS04475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EC958_RS04485	COG3593	DNA synthesis involved in DNA repair
EC958_RS04490	COG2990	Protein conserved in bacteria
EC958_RS04495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC958_RS04505	COG1278	Cold shock
EC958_RS04515	COG0542	response to heat
EC958_RS04535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EC958_RS04540	COG4988	ABC transporter
EC958_RS04545	COG0492	ferredoxin-NADP+ reductase activity
EC958_RS04550	COG1522	sequence-specific DNA binding
EC958_RS04565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EC958_RS04835	COG0243	molybdopterin cofactor binding
EC958_RS04840	COG0437	4 iron, 4 sulfur cluster binding
EC958_RS04845	COG3302	dmso reductase anchor subunit
EC958_RS04850	COG1335	isochorismatase
EC958_RS04860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC958_RS04865	COG1882	Formate acetyltransferase
EC958_RS04875	COG1944	ATP diphosphatase activity
EC958_RS04880	COG2323	membrane
EC958_RS05015	COG2369	cell adhesion
EC958_RS05110	COG3267	Type II secretory pathway component ExeA
EC958_RS05110	COG3409	Peptidoglycan-binding domain 1 protein
EC958_RS05170	COG0501	Belongs to the peptidase M48B family
EC958_RS05180	COG0539	negative regulation of cytoplasmic translation
EC958_RS05190	COG2333	competence protein COMEC
EC958_RS05190	COG0658	competence protein
EC958_RS05205	COG3214	Protein conserved in bacteria
EC958_RS05220	COG3173	Aminoglycoside phosphotransferase
EC958_RS05225	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EC958_RS05230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EC958_RS05240	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EC958_RS05250	COG2989	Protein conserved in bacteria
EC958_RS05255	COG3108	Peptidase M15
EC958_RS05260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EC958_RS05265	COG1448	Aminotransferase
EC958_RS05290	COG0308	aminopeptidase N
EC958_RS05295	COG1116	anion transmembrane transporter activity
EC958_RS05300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC958_RS05310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EC958_RS05315	COG0431	NADPH-dependent FMN reductase
EC958_RS05330	COG0633	Ferredoxin
EC958_RS05330	COG3217	Mosc domain protein beta barrel domain protein
EC958_RS05340	COG0488	(ABC) transporter
EC958_RS05345	COG2995	paraquat-inducible protein a
EC958_RS05350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EC958_RS05350	COG3008	intermembrane lipid transfer
EC958_RS05355	COG3009	Protein conserved in bacteria
EC958_RS05360	COG3130	regulation of translation
EC958_RS05370	COG1067	ATP-dependent peptidase activity
EC958_RS05395	COG3070	regulator of competence-specific genes
EC958_RS05400	COG1289	transmembrane transporter activity
EC958_RS05405	COG3304	Inner membrane component domain
EC958_RS05410	COG0210	DNA helicase
EC958_RS05430	COG1832	CoA-binding protein
EC958_RS05445	COG1254	Belongs to the acylphosphatase family
EC958_RS05450	COG2920	part of a sulfur-relay system
EC958_RS05455	COG0670	Belongs to the BI1 family
EC958_RS05465	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EC958_RS05470	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EC958_RS05475	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
EC958_RS05480	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EC958_RS05485	COG1999	signal sequence binding
EC958_RS05490	COG1773	rubredoxin
EC958_RS05495	COG1271	oxidase subunit
EC958_RS05500	COG1294	oxidase, subunit
EC958_RS05515	COG1278	Cold shock
EC958_RS05520	COG1278	Cold shock
EC958_RS05535	COG0348	domain, Protein
EC958_RS05545	COG1879	ABC-type sugar transport system periplasmic component
EC958_RS05550	COG0745	RESPONSE REGULATOR receiver
EC958_RS05555	COG3005	denitrification pathway
EC958_RS05560	COG0243	molybdopterin cofactor binding
EC958_RS05600	COG3729	General stress protein
EC958_RS05605	COG2233	PERMEase
EC958_RS05640	COG1309	transcriptional regulator
EC958_RS05645	COG0506	proline dehydrogenase activity
EC958_RS05645	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EC958_RS05645	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EC958_RS05655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC958_RS05675	COG1702	phosphate starvation-inducible protein PhoH
EC958_RS05680	COG3658	cytochrome
EC958_RS05685	COG1215	transferase activity, transferring glycosyl groups
EC958_RS05690	COG0726	polysaccharide deacetylase
EC958_RS05690	COG1649	PFAM Uncharacterised BCR, COG1649
EC958_RS05695	COG0457	Tetratricopeptide repeat
EC958_RS05700	COG3706	GGDEF domain
EC958_RS05725	COG3381	protein complex oligomerization
EC958_RS05735	COG1462	curli production assembly transport component CsgG
EC958_RS05750	COG2197	response regulator
EC958_RS05780	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EC958_RS05785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC958_RS05810	COG2943	transferase activity, transferring hexosyl groups
EC958_RS05815	COG5645	(Lipo)protein
EC958_RS05835	COG1560	Kdo2-lipid A biosynthetic process
EC958_RS05845	COG2353	YceI-like domain
EC958_RS05850	COG3038	cytochrome b561
EC958_RS05885	COG2999	glutathione oxidoreductase activity
EC958_RS05895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC958_RS05905	COG0673	inositol 2-dehydrogenase activity
EC958_RS05910	COG0728	peptidoglycan biosynthetic process
EC958_RS05915	COG3418	PFAM FlgN family protein
EC958_RS05920	COG2747	anti-sigma28 factor FlgM
EC958_RS05925	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EC958_RS05930	COG1815	bacterial-type flagellum-dependent cell motility
EC958_RS05935	COG1558	bacterial-type flagellum-dependent cell motility
EC958_RS05940	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EC958_RS05945	COG1749	Flagellar hook protein flgE
EC958_RS05950	COG4787	bacterial-type flagellum-dependent cell motility
EC958_RS05955	COG4786	Flagellar basal body rod
EC958_RS05970	COG3951	Flagellar rod assembly protein muramidase FlgJ
EC958_RS05970	COG1705	Flagellar rod assembly protein muramidase FlgJ
EC958_RS05975	COG1256	bacterial-type flagellum assembly
EC958_RS05980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EC958_RS05985	COG1530	ribonuclease E activity
EC958_RS05995	COG0564	pseudouridine synthase activity
EC958_RS06000	COG0424	maF-like protein
EC958_RS06005	COG1399	metal-binding, possibly nucleic acid-binding protein
EC958_RS06025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EC958_RS06030	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS06040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EC958_RS06045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EC958_RS06050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EC958_RS06060	COG0470	DNA polymerase III
EC958_RS06065	COG0084	hydrolase, TatD family'
EC958_RS06070	COG1263	PTS System
EC958_RS06070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS06075	COG4773	Receptor
EC958_RS06080	COG0537	adenosine 5'-monophosphoramidase activity
EC958_RS06085	COG5633	Lipoprotein
EC958_RS06090	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
EC958_RS06095	COG0510	thiamine kinase activity
EC958_RS06110	COG1252	NADH dehydrogenase
EC958_RS06115	COG3134	Outer membrane lipoprotein
EC958_RS06120	COG1309	transcriptional regulator
EC958_RS06130	COG1376	ErfK ybiS ycfS ynhG family protein
EC958_RS06130	COG1388	LysM domain
EC958_RS06135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EC958_RS06140	COG4763	Acyl-transferase
EC958_RS06145	COG4591	ABC-type transport system involved in lipoprotein release permease component
EC958_RS06155	COG4591	ABC-type transport system involved in lipoprotein release permease component
EC958_RS06165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EC958_RS06170	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EC958_RS06180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EC958_RS06185	COG1177	transmembrane transport
EC958_RS06195	COG3842	ATPase activity
EC958_RS06210	COG2850	peptidyl-arginine hydroxylation
EC958_RS06215	COG2205	protein histidine kinase activity
EC958_RS06225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EC958_RS06245	COG1187	pseudouridine synthase activity
EC958_RS06250	COG0538	isocitrate dehydrogenase activity
EC958_RS06345	COG1388	LysM domain
EC958_RS06345	COG1470	cell adhesion involved in biofilm formation
EC958_RS06530	COG5301	cellulose 1,4-beta-cellobiosidase activity
EC958_RS06545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EC958_RS06550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EC958_RS06555	COG1121	(ABC) transporter
EC958_RS06585	COG5562	phage envelope protein
EC958_RS06590	COG0789	Transcriptional regulator
EC958_RS06595	COG2200	EAL domain
EC958_RS06675	COG2894	cell division
EC958_RS06705	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC958_RS06720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EC958_RS06725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EC958_RS06735	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EC958_RS06745	COG2719	SpoVR family
EC958_RS06755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EC958_RS06765	COG1619	proteins homologs of microcin C7 resistance protein MccF
EC958_RS06775	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EC958_RS06790	COG0157	Belongs to the NadC ModD family
EC958_RS06795	COG0500	methyltransferase
EC958_RS06800	COG1120	ATPase activity
EC958_RS06805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC958_RS06810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EC958_RS06820	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EC958_RS06820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS06820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EC958_RS06825	COG1461	Dihydroxyacetone kinase
EC958_RS06830	COG2376	Dihydroxyacetone kinase
EC958_RS06835	COG3284	Transcriptional regulator
EC958_RS06900	COG2003	Belongs to the UPF0758 family
EC958_RS06975	COG0582	viral genome integration into host DNA
EC958_RS06980	COG0012	GTP binding
EC958_RS06995	COG0659	secondary active sulfate transmembrane transporter activity
EC958_RS07000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EC958_RS07025	COG2890	protein-(glutamine-N5) methyltransferase activity
EC958_RS07030	COG3094	Invasion gene expression up-regulator, SirB
EC958_RS07035	COG2912	Transglutaminase-like superfamily
EC958_RS07050	COG0387	Pfam Sodium calcium exchanger
EC958_RS07055	COG4572	Cation transport regulator
EC958_RS07060	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EC958_RS07065	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EC958_RS07070	COG4932	domain protein
EC958_RS07075	COG2197	response regulator
EC958_RS07080	COG3850	Histidine kinase
EC958_RS07090	COG2223	nitrite transmembrane transporter activity
EC958_RS07095	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EC958_RS07100	COG1140	nitrate reductase beta subunit
EC958_RS07105	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EC958_RS07110	COG2181	nitrate reductase activity
EC958_RS07115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EC958_RS07120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC958_RS07155	COG0788	formyltetrahydrofolate deformylase activity
EC958_RS07165	COG1752	Esterase of the alpha-beta hydrolase superfamily
EC958_RS07170	COG0745	RESPONSE REGULATOR receiver
EC958_RS07175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EC958_RS07185	COG1435	thymidine kinase activity
EC958_RS07200	COG1012	belongs to the aldehyde dehydrogenase family
EC958_RS07200	COG1454	alcohol dehydrogenase
EC958_RS07205	COG2095	MarC family integral membrane protein
EC958_RS07210	COG4166	transmembrane transport
EC958_RS07215	COG0601	transmembrane transport
EC958_RS07220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC958_RS07225	COG0444	Belongs to the ABC transporter superfamily
EC958_RS07230	COG4608	Belongs to the ABC transporter superfamily
EC958_RS07250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC958_RS07255	COG2350	Protein conserved in bacteria
EC958_RS07265	COG1607	acyl-coa hydrolase
EC958_RS07280	COG3047	cAMP biosynthetic process
EC958_RS07295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC958_RS07340	COG1846	Transcriptional regulator
EC958_RS07345	COG1484	DNA-dependent DNA replication
EC958_RS07350	COG1846	Transcriptional regulator
EC958_RS07360	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EC958_RS07380	COG1403	HNH endonuclease
EC958_RS07390	COG0484	heat shock protein binding
EC958_RS07590	COG4584	PFAM Integrase catalytic
EC958_RS07595	COG1484	DNA-dependent DNA replication
EC958_RS07630	COG0500	methyltransferase
EC958_RS07665	COG0512	Glutamine amidotransferase of anthranilate synthase
EC958_RS07665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EC958_RS07670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EC958_RS07675	COG0613	PHP domain protein
EC958_RS07680	COG0009	L-threonylcarbamoyladenylate synthase
EC958_RS07685	COG4907	membrane protein (DUF2207)
EC958_RS07690	COG1187	pseudouridine synthase activity
EC958_RS07705	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EC958_RS07710	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS07720	COG0616	signal peptide processing
EC958_RS07735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC958_RS07740	COG0583	DNA-binding transcription factor activity
EC958_RS07760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EC958_RS07770	COG0671	phosphoesterase, PA-phosphatase related
EC958_RS07775	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EC958_RS07780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EC958_RS07790	COG0023	Translation Initiation Factor
EC958_RS07800	COG1349	DNA-binding transcription factor activity
EC958_RS07810	COG5001	Diguanylate cyclase
EC958_RS07825	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC958_RS07825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC958_RS07830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EC958_RS07840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC958_RS07845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC958_RS07855	COG2814	Major facilitator Superfamily
EC958_RS07860	COG4172	Belongs to the ABC transporter superfamily
EC958_RS07865	COG4172	Belongs to the ABC transporter superfamily
EC958_RS07870	COG4171	peptide transport system, permease
EC958_RS07875	COG4168	peptide transport system, permease
EC958_RS07880	COG4166	transmembrane transport
EC958_RS07895	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EC958_RS07900	COG1842	Phage shock protein A
EC958_RS07910	COG1983	PspC domain protein
EC958_RS07920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EC958_RS07925	COG0366	Alpha amylase catalytic
EC958_RS07930	COG1653	transport
EC958_RS07935	COG1175	transmembrane transport
EC958_RS07940	COG0395	ABC-type sugar transport system, permease component
EC958_RS07945	COG1063	alcohol dehydrogenase
EC958_RS07950	COG1082	Xylose isomerase domain protein TIM barrel
EC958_RS07955	COG0673	inositol 2-dehydrogenase activity
EC958_RS07960	COG1554	hydrolase, family 65, central catalytic
EC958_RS07965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC958_RS07980	COG1609	Transcriptional regulator
EC958_RS07985	COG3106	COG3106 Predicted ATPase
EC958_RS07995	COG3283	Transcriptional regulator of aromatic amino acids metabolism
EC958_RS08000	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EC958_RS08005	COG4948	Mandelate Racemase Muconate Lactonizing
EC958_RS08010	COG2866	Carboxypeptidase
EC958_RS08015	COG0702	epimerase
EC958_RS08020	COG1073	alpha beta
EC958_RS08025	COG0583	DNA-binding transcription factor activity
EC958_RS08035	COG4166	transmembrane transport
EC958_RS08040	COG0668	transmembrane transport
EC958_RS08045	COG3182	Iron-regulated membrane protein
EC958_RS08050	COG0589	response to stress
EC958_RS08055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC958_RS08060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC958_RS08075	COG2207	Transcriptional regulator
EC958_RS08090	COG2840	Smr protein MutS2
EC958_RS08095	COG3706	GGDEF domain
EC958_RS08110	COG0513	Belongs to the DEAD box helicase family
EC958_RS08135	COG0589	response to stress
EC958_RS08140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC958_RS08145	COG1013	pyruvate-flavodoxin oxidoreductase activity
EC958_RS08145	COG0674	pyruvate-flavodoxin oxidoreductase activity
EC958_RS08145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC958_RS08145	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EC958_RS08150	COG3042	response to heat
EC958_RS08155	COG3187	Heat shock protein
EC958_RS08160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC958_RS08165	COG2911	Protein conserved in bacteria
EC958_RS08175	COG3784	Protein of unknown function (DUF1318)
EC958_RS08200	COG0667	Aldo Keto reductase
EC958_RS08210	COG1643	Atp-dependent helicase
EC958_RS08215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EC958_RS08220	COG1012	belongs to the aldehyde dehydrogenase family
EC958_RS08225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EC958_RS08230	COG3038	cytochrome b561
EC958_RS08255	COG0583	DNA-binding transcription factor activity
EC958_RS08260	COG5383	Protein conserved in bacteria
EC958_RS08275	COG2841	Protein conserved in bacteria
EC958_RS08280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC958_RS08285	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EC958_RS08290	COG1275	C4-dicarboxylate transporter malic acid transport protein
EC958_RS08295	COG0500	methyltransferase
EC958_RS08305	COG3135	benzoate transporter
EC958_RS08310	COG1396	sequence-specific DNA binding
EC958_RS08315	COG0826	peptidase U32
EC958_RS08330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC958_RS08335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EC958_RS08340	COG3842	ATPase activity
EC958_RS08345	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC958_RS08350	COG1177	transmembrane transport
EC958_RS08375	COG3238	Protein conserved in bacteria
EC958_RS08380	COG1247	-acetyltransferase
EC958_RS08390	COG4772	TonB-dependent receptor
EC958_RS08400	COG1113	amino acid transport
EC958_RS08405	COG5433	transposase activity
EC958_RS08410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC958_RS08415	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EC958_RS08420	COG0384	phenazine biosynthesis protein PhzF
EC958_RS08425	COG2181	nitrate reductase activity
EC958_RS08430	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EC958_RS08435	COG1140	nitrate reductase beta subunit
EC958_RS08440	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EC958_RS08445	COG2223	nitrite transmembrane transporter activity
EC958_RS08450	COG0697	spore germination
EC958_RS08465	COG0437	4 iron, 4 sulfur cluster binding
EC958_RS08470	COG2864	formate dehydrogenase
EC958_RS08475	COG3093	addiction module antidote protein HigA
EC958_RS08485	COG1064	alcohol dehydrogenase
EC958_RS08505	COG1764	response to oxidative stress
EC958_RS08510	COG2199	diguanylate cyclase activity
EC958_RS08510	COG2200	EAL domain
EC958_RS08510	COG2202	Pas domain
EC958_RS08520	COG1649	PFAM Uncharacterised BCR, COG1649
EC958_RS08525	COG0531	amino acid
EC958_RS08530	COG0076	glutamate decarboxylase activity
EC958_RS08545	COG0641	radical SAM
EC958_RS08550	COG3119	arylsulfatase activity
EC958_RS08555	COG2207	Transcriptional regulator
EC958_RS08565	COG0243	molybdopterin cofactor binding
EC958_RS08570	COG3539	Fimbrial protein
EC958_RS08575	COG3539	Fimbrial protein
EC958_RS08580	COG3539	Fimbrial protein
EC958_RS08585	COG3188	usher protein
EC958_RS08595	COG3539	Fimbrial protein
EC958_RS08600	COG3550	peptidyl-serine autophosphorylation
EC958_RS08605	COG1396	sequence-specific DNA binding
EC958_RS08615	COG3781	membrane
EC958_RS08630	COG2199	diguanylate cyclase activity
EC958_RS08640	COG2066	Belongs to the glutaminase family
EC958_RS08645	COG1012	belongs to the aldehyde dehydrogenase family
EC958_RS08650	COG0583	DNA-binding transcription factor activity
EC958_RS08665	COG1846	Transcriptional regulator
EC958_RS08670	COG4977	sequence-specific DNA binding
EC958_RS08680	COG0697	spore germination
EC958_RS08685	COG2814	Major facilitator Superfamily
EC958_RS08695	COG3706	GGDEF domain
EC958_RS08705	COG0339	signal peptide processing
EC958_RS08710	COG4221	oxidoreductase activity
EC958_RS08715	COG1802	Transcriptional regulator
EC958_RS08725	COG0246	Mannitol dehydrogenase
EC958_RS08730	COG0477	Major facilitator Superfamily
EC958_RS08735	COG1063	alcohol dehydrogenase
EC958_RS08740	COG4948	Mandelate Racemase Muconate Lactonizing
EC958_RS08755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC958_RS08770	COG0243	molybdopterin cofactor binding
EC958_RS08780	COG0437	4 iron, 4 sulfur cluster binding
EC958_RS08785	COG3302	dmso reductase anchor subunit
EC958_RS08790	COG3381	protein complex oligomerization
EC958_RS08800	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EC958_RS08805	COG1940	carbohydrate kinase activity
EC958_RS08810	COG0583	DNA-binding transcription factor activity
EC958_RS08815	COG2814	Major facilitator Superfamily
EC958_RS08830	COG3591	Belongs to the peptidase S1B family
EC958_RS08845	COG0628	permease
EC958_RS08850	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EC958_RS08855	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EC958_RS08865	COG0531	amino acid
EC958_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS08875	COG3136	membrane protein required for alginate biosynthesis
EC958_RS08880	COG0745	RESPONSE REGULATOR receiver
EC958_RS08885	COG2205	protein histidine kinase activity
EC958_RS08895	COG0114	fumarate hydratase activity
EC958_RS08900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EC958_RS08900	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EC958_RS08905	COG1482	cell wall glycoprotein biosynthetic process
EC958_RS08910	COG5339	Protein conserved in bacteria
EC958_RS08930	COG3250	beta-galactosidase activity
EC958_RS08935	COG1309	transcriptional regulator
EC958_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS08945	COG1609	Transcriptional regulator
EC958_RS08950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS08950	COG1263	PTS System
EC958_RS08955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EC958_RS08965	COG0673	inositol 2-dehydrogenase activity
EC958_RS09005	COG4659	FMN binding
EC958_RS09015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EC958_RS09025	COG3104	oligopeptide transport
EC958_RS09030	COG0625	glutathione transferase activity
EC958_RS09050	COG3895	Periplasmic Protein
EC958_RS09060	COG3133	Outer membrane lipoprotein
EC958_RS09075	COG1566	PFAM secretion protein HlyD family protein
EC958_RS09080	COG1289	transmembrane transporter activity
EC958_RS09085	COG2032	superoxide dismutase activity
EC958_RS09090	COG4989	oxidoreductase activity
EC958_RS09095	COG3313	Fe-S protein
EC958_RS09100	COG1309	transcriptional regulator
EC958_RS09105	COG1902	pentaerythritol trinitrate reductase activity
EC958_RS09110	COG0346	lactoylglutathione lyase activity
EC958_RS09125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EC958_RS09130	COG0791	NLP P60 protein
EC958_RS09135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EC958_RS09140	COG2814	Major facilitator Superfamily
EC958_RS09155	COG0583	DNA-binding transcription factor activity
EC958_RS09160	COG2814	Major facilitator Superfamily
EC958_RS09165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EC958_RS09170	COG0307	riboflavin synthase, alpha
EC958_RS09180	COG3468	outer membrane autotransporter barrel domain protein
EC958_RS09200	COG4529	Protein conserved in bacteria
EC958_RS09210	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EC958_RS09215	COG0437	4 iron, 4 sulfur cluster binding
EC958_RS09225	COG2414	aldehyde ferredoxin oxidoreductase
EC958_RS09230	COG0437	4 iron, 4 sulfur cluster binding
EC958_RS09240	COG0469	pyruvate kinase activity
EC958_RS09245	COG4238	major outer membrane lipoprotein
EC958_RS09250	COG1376	ErfK ybiS ycfS ynhG family protein
EC958_RS09265	COG0719	Fe-S assembly protein
EC958_RS09270	COG0396	ATPase activity
EC958_RS09275	COG0719	Fe-S assembly protein
EC958_RS09280	COG0316	Belongs to the HesB IscA family
EC958_RS09290	COG2050	protein possibly involved in aromatic compounds catabolism
EC958_RS09295	COG0247	lactate metabolic process
EC958_RS09295	COG0277	FAD linked oxidase domain protein
EC958_RS09300	COG0628	permease
EC958_RS09310	COG0738	Major facilitator superfamily
EC958_RS09315	COG2271	Major facilitator Superfamily
EC958_RS09330	COG4670	ketone body catabolic process
EC958_RS09335	COG1960	acyl-CoA dehydrogenase activity
EC958_RS09340	COG2207	Transcriptional regulator
EC958_RS09340	COG1917	Cupin 2, conserved barrel domain protein
EC958_RS09350	COG2086	electron transfer activity
EC958_RS09355	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EC958_RS09360	COG0644	oxidoreductase
EC958_RS09365	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EC958_RS09370	COG0318	PFAM AMP-dependent synthetase and ligase
EC958_RS09375	COG0574	Belongs to the PEP-utilizing enzyme family
EC958_RS09375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EC958_RS09390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EC958_RS09395	COG4256	Hemin uptake protein
EC958_RS09405	COG2200	EAL domain
EC958_RS09410	COG0791	NLP P60 protein
EC958_RS09420	COG0386	Belongs to the glutathione peroxidase family
EC958_RS09480	COG3137	Salt-induced outer membrane protein
EC958_RS09485	COG1105	Belongs to the carbohydrate kinase PfkB family
EC958_RS09495	COG3001	Fructosamine kinase
EC958_RS09505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC958_RS09510	COG1988	membrane-bound metal-dependent
EC958_RS09515	COG1823	symporter activity
EC958_RS09525	COG0753	catalase activity
EC958_RS09530	COG3394	polysaccharide catabolic process
EC958_RS09535	COG1486	melibiose metabolic process
EC958_RS09540	COG2169	Transcriptional regulator
EC958_RS09540	COG1917	Cupin 2, conserved barrel domain protein
EC958_RS09545	COG1447	Phosphotransferase system cellobiose-specific component IIA
EC958_RS09550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC958_RS09555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC958_RS09560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC958_RS09575	COG0322	excinuclease ABC activity
EC958_RS09585	COG3678	ATP-independent chaperone mediated protein folding
EC958_RS09615	COG0708	Exodeoxyribonuclease III
EC958_RS09620	COG0398	Pfam SNARE associated Golgi protein
EC958_RS09630	COG0398	Pfam SNARE associated Golgi protein
EC958_RS09635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC958_RS09640	COG4134	Bacterial extracellular solute-binding protein
EC958_RS09645	COG4135	transport system, permease component
EC958_RS09650	COG4136	ATPase activity
EC958_RS09655	COG2897	thiosulfate sulfurtransferase activity
EC958_RS09660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EC958_RS09665	COG0494	nUDIX hydrolase
EC958_RS09675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EC958_RS09680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC958_RS09685	COG0709	Synthesizes selenophosphate from selenide and ATP
EC958_RS09695	COG0778	Nitroreductase
EC958_RS09705	COG0616	signal peptide processing
EC958_RS09715	COG0252	asparaginase activity
EC958_RS09720	COG1335	isochorismatase
EC958_RS09725	COG2814	Major facilitator Superfamily
EC958_RS09730	COG1349	DNA-binding transcription factor activity
EC958_RS09735	COG0667	Aldo Keto reductase
EC958_RS09740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS09745	COG0191	fructose-bisphosphate aldolase activity
EC958_RS09750	COG1063	alcohol dehydrogenase
EC958_RS09755	COG2271	Major facilitator Superfamily
EC958_RS09760	COG1063	alcohol dehydrogenase
EC958_RS09765	COG3139	Protein of unknown function (DUF1315)
EC958_RS09775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EC958_RS09780	COG0676	glucose-6-phosphate 1-epimerase activity
EC958_RS09785	COG0656	L-ascorbic acid biosynthetic process
EC958_RS09790	COG3713	MltA-interacting MipA family protein
EC958_RS09795	COG2766	serine protein kinase
EC958_RS09805	COG2199	diguanylate cyclase activity
EC958_RS09810	COG2199	diguanylate cyclase activity
EC958_RS09815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EC958_RS09830	COG2207	Transcriptional regulator
EC958_RS09835	COG2807	transmembrane transport
EC958_RS09840	COG3189	MarR family transcriptional regulator
EC958_RS09845	COG3042	response to heat
EC958_RS09850	COG2199	diguanylate cyclase activity
EC958_RS09850	COG2203	Gaf domain
EC958_RS09860	COG2261	transglycosylase associated protein
EC958_RS09870	COG3615	Tellurite resistance protein tehB
EC958_RS09890	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EC958_RS09895	COG0318	PFAM AMP-dependent synthetase and ligase
EC958_RS09900	COG3065	identical protein binding
EC958_RS09905	COG1214	PFAM Peptidase M22, glycoprotease
EC958_RS09910	COG1199	ATP-dependent helicase activity
EC958_RS09915	COG0251	oxidation-reduction process
EC958_RS09935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EC958_RS09945	COG1760	l-serine dehydratase
EC958_RS09950	COG2200	EAL domain
EC958_RS09955	COG1253	flavin adenine dinucleotide binding
EC958_RS09965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS09965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS09970	COG3715	PTS system
EC958_RS09975	COG3716	PTS system mannose fructose sorbose family IID component
EC958_RS09995	COG2226	methyltransferase
EC958_RS10030	COG1414	Transcriptional regulator
EC958_RS10035	COG2814	Major facilitator Superfamily
EC958_RS10045	COG0793	Belongs to the peptidase S41A family
EC958_RS10055	COG1956	GAF domain-containing protein
EC958_RS10060	COG2995	paraquat-inducible protein a
EC958_RS10065	COG3008	intermembrane lipid transfer
EC958_RS10085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EC958_RS10100	COG1276	copper resistance
EC958_RS10105	COG2372	response to copper ion
EC958_RS10115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC958_RS10120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC958_RS10125	COG1770	oligopeptidase
EC958_RS10130	COG2979	Protein of unknown function (DUF533)
EC958_RS10145	COG3141	response to X-ray
EC958_RS10155	COG0800	Aldolase
EC958_RS10160	COG0129	dihydroxy-acid dehydratase activity
EC958_RS10165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EC958_RS10175	COG1737	Transcriptional regulator
EC958_RS10180	COG0469	pyruvate kinase activity
EC958_RS10185	COG1560	Kdo2-lipid A biosynthetic process
EC958_RS10190	COG0739	heme binding
EC958_RS10195	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EC958_RS10205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EC958_RS10245	COG0217	transcriptional regulatory protein
EC958_RS10250	COG0494	nUDIX hydrolase
EC958_RS10260	COG1335	isochorismatase
EC958_RS10265	COG1801	Protein of unknown function DUF72
EC958_RS10270	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EC958_RS10285	COG0243	molybdopterin cofactor binding
EC958_RS10290	COG3005	denitrification pathway
EC958_RS10300	COG3102	Protein conserved in bacteria
EC958_RS10315	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EC958_RS10320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EC958_RS10325	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EC958_RS10330	COG0745	RESPONSE REGULATOR receiver
EC958_RS10340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EC958_RS10350	COG0840	transmembrane signaling receptor activity
EC958_RS10355	COG0835	chemotaxis
EC958_RS10360	COG0643	Histidine kinase
EC958_RS10360	COG2198	Histidine kinase
EC958_RS10365	COG1360	Flagellar Motor Protein
EC958_RS10370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EC958_RS10385	COG0589	response to stress
EC958_RS10395	COG1877	trehalose-phosphatase activity
EC958_RS10400	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC958_RS10405	COG1129	ABC transporter
EC958_RS10410	COG1879	ABC-type sugar transport system periplasmic component
EC958_RS10415	COG1528	Iron-storage protein
EC958_RS10435	COG1528	Iron-storage protein
EC958_RS10445	COG0814	amino acid
EC958_RS10450	COG3318	Belongs to the UPF0149 family
EC958_RS10450	COG3012	SEC-C Motif Domain Protein
EC958_RS10685	COG0305	Participates in initiation and elongation during chromosome replication
EC958_RS10770	COG2197	response regulator
EC958_RS10785	COG2197	response regulator
EC958_RS10790	COG1126	abc transporter atp-binding protein
EC958_RS10795	COG0765	amino acid transport
EC958_RS10805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC958_RS10815	COG1191	sigma factor activity
EC958_RS10820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EC958_RS10825	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EC958_RS10830	COG1516	flagellar protein fliS
EC958_RS10840	COG0366	Alpha amylase catalytic
EC958_RS10850	COG2391	methyltransferase activity
EC958_RS10855	COG0425	Belongs to the sulfur carrier protein TusA family
EC958_RS10870	COG2207	Transcriptional regulator
EC958_RS10875	COG1881	PFAM PEBP family protein
EC958_RS10880	COG2076	Multidrug Resistance protein
EC958_RS10895	COG1766	The M ring may be actively involved in energy transduction
EC958_RS10900	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EC958_RS10905	COG1317	bacterial-type flagellum organization
EC958_RS10910	COG1157	protein secretion by the type III secretion system
EC958_RS10915	COG2882	bacterial-type flagellum organization
EC958_RS10920	COG3144	bacterial-type flagellum assembly
EC958_RS10925	COG1580	Controls the rotational direction of flagella during chemotaxis
EC958_RS10930	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EC958_RS10935	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EC958_RS10940	COG3190	flagellar
EC958_RS10945	COG1338	Plays a role in the flagellum-specific transport system
EC958_RS10950	COG1987	bacterial-type flagellum assembly
EC958_RS10955	COG1684	flagellar biosynthetic protein fliR
EC958_RS10960	COG2197	response regulator
EC958_RS10985	COG5475	Uncharacterized small protein (DUF2158)
EC958_RS10990	COG2354	Protein conserved in bacteria
EC958_RS10995	COG0697	spore germination
EC958_RS11000	COG3727	T/G mismatch-specific endonuclease activity
EC958_RS11005	COG0270	DNA (cytosine-5-)-methyltransferase activity
EC958_RS11010	COG1418	mRNA catabolic process
EC958_RS11025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC958_RS11040	COG2205	protein histidine kinase activity
EC958_RS11045	COG0745	RESPONSE REGULATOR receiver
EC958_RS11050	COG2351	hydroxyisourate hydrolase activity
EC958_RS11080	COG3443	Belongs to the bacterial solute-binding protein 9 family
EC958_RS11105	COG5301	cellulose 1,4-beta-cellobiosidase activity
EC958_RS11230	COG3772	lysozyme
EC958_RS11270	COG0484	heat shock protein binding
EC958_RS11280	COG1403	HNH endonuclease
EC958_RS11325	COG1846	Transcriptional regulator
EC958_RS11365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC958_RS11395	COG0582	viral genome integration into host DNA
EC958_RS11400	COG1169	isochorismate synthase
EC958_RS11405	COG2814	Major facilitator Superfamily
EC958_RS11410	COG1132	(ABC) transporter
EC958_RS11415	COG1132	(ABC) transporter
EC958_RS11415	COG2375	cellular response to nickel ion
EC958_RS11425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EC958_RS11425	COG3433	isochorismatase activity
EC958_RS11425	COG2226	methyltransferase
EC958_RS11445	COG1021	2,3-dihydroxybenzoate-AMP ligase
EC958_RS11450	COG4771	TonB-dependent receptor
EC958_RS11455	COG2373	Large extracellular alpha-helical protein
EC958_RS11455	COG4932	domain protein
EC958_RS11455	COG1388	LysM domain
EC958_RS11480	COG0477	Major facilitator Superfamily
EC958_RS11485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EC958_RS11490	COG0217	transcriptional regulatory protein
EC958_RS11500	COG0534	Mate efflux family protein
EC958_RS11510	COG0583	DNA-binding transcription factor activity
EC958_RS11515	COG0583	DNA-binding transcription factor activity
EC958_RS11525	COG1376	ErfK ybiS ycfS ynhG family protein
EC958_RS11540	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
EC958_RS11555	COG4771	TonB-dependent receptor
EC958_RS11560	COG1475	DNA binding
EC958_RS11565	COG3969	phosphoadenosine phosphosulfate
EC958_RS11570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EC958_RS11575	COG1215	transferase activity, transferring glycosyl groups
EC958_RS11595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS11610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EC958_RS11665	COG3547	Transposase (IS116 IS110 IS902 family)
EC958_RS11705	COG1120	ATPase activity
EC958_RS11740	COG3436	PFAM IS66 Orf2 family protein
EC958_RS11745	COG4372	Transposase
EC958_RS11770	COG4584	PFAM Integrase catalytic
EC958_RS11775	COG1484	DNA-dependent DNA replication
EC958_RS11805	COG2003	Belongs to the UPF0758 family
EC958_RS11850	COG1289	transmembrane transporter activity
EC958_RS11860	COG1686	Belongs to the peptidase S11 family
EC958_RS11865	COG2925	Exonuclease
EC958_RS11880	COG0531	amino acid
EC958_RS11885	COG0583	DNA-binding transcription factor activity
EC958_RS11890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC958_RS11895	COG4115	mRNA cleavage
EC958_RS11900	COG2161	toxin-antitoxin pair type II binding
EC958_RS11910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EC958_RS11920	COG0131	Imidazoleglycerol-phosphate dehydratase
EC958_RS11920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EC958_RS11925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EC958_RS11945	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EC958_RS11950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EC958_RS11955	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EC958_RS11965	COG0438	transferase activity, transferring glycosyl groups
EC958_RS11970	COG0110	maltose O-acetyltransferase activity
EC958_RS11980	COG0438	transferase activity, transferring glycosyl groups
EC958_RS12000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC958_RS12005	COG1091	dTDP-4-dehydrorhamnose reductase activity
EC958_RS12010	COG1088	dTDP-glucose 4,6-dehydratase activity
EC958_RS12015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EC958_RS12025	COG0438	transferase activity, transferring glycosyl groups
EC958_RS12030	COG2327	Polysaccharide pyruvyl transferase
EC958_RS12035	COG2244	polysaccharide biosynthetic process
EC958_RS12040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EC958_RS12045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EC958_RS12050	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EC958_RS12050	COG0662	Cupin 2, conserved barrel domain protein
EC958_RS12055	COG0297	glycogen (starch) synthase activity
EC958_RS12060	COG1051	belongs to the nudix hydrolase family
EC958_RS12065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC958_RS12070	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EC958_RS12075	COG0110	maltose O-acetyltransferase activity
EC958_RS12080	COG1216	Glycosyl transferase, family 2
EC958_RS12090	COG0438	transferase activity, transferring glycosyl groups
EC958_RS12095	COG1045	serine acetyltransferase
EC958_RS12100	COG0463	Glycosyl transferase, family 2
EC958_RS12105	COG0489	protein tyrosine kinase activity
EC958_RS12105	COG3206	protein involved in exopolysaccharide biosynthesis
EC958_RS12110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EC958_RS12115	COG1596	polysaccharide export
EC958_RS12120	COG1253	flavin adenine dinucleotide binding
EC958_RS12125	COG2982	Protein involved in outer membrane biogenesis
EC958_RS12135	COG0572	uridine kinase
EC958_RS12140	COG3447	MASE1 domain protein
EC958_RS12140	COG5001	Diguanylate cyclase
EC958_RS12140	COG5002	protein histidine kinase activity
EC958_RS12145	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EC958_RS12150	COG0443	Heat shock 70 kDa protein
EC958_RS12155	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
EC958_RS12160	COG0631	protein serine/threonine phosphatase activity
EC958_RS12165	COG4245	von Willebrand factor, type A
EC958_RS12190	COG2205	protein histidine kinase activity
EC958_RS12195	COG0745	RESPONSE REGULATOR receiver
EC958_RS12205	COG0826	peptidase U32
EC958_RS12225	COG1063	alcohol dehydrogenase
EC958_RS12235	COG3414	Phosphotransferase system galactitol-specific IIB component
EC958_RS12240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS12255	COG1830	Aldolase
EC958_RS12260	COG2211	Major facilitator Superfamily
EC958_RS12265	COG1397	ADP-ribosylglycohydrolase
EC958_RS12270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS12275	COG2188	Transcriptional regulator
EC958_RS12280	COG3757	hydrolase, family 25
EC958_RS12285	COG0351	phosphomethylpyrimidine kinase
EC958_RS12305	COG5455	response to cobalt ion
EC958_RS12330	COG3188	usher protein
EC958_RS12335	COG3121	Chaperone
EC958_RS12340	COG3539	Fimbrial protein
EC958_RS12355	COG0489	protein tyrosine kinase activity
EC958_RS12365	COG3831	ATPase activity
EC958_RS12370	COG3831	ATPase activity
EC958_RS12375	COG3831	ATPase activity
EC958_RS12390	COG0714	Associated with various cellular activities
EC958_RS12395	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EC958_RS12400	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EC958_RS12405	COG4715	Zinc finger, swim domain protein
EC958_RS12410	COG4808	Protein conserved in bacteria
EC958_RS12415	COG4807	Protein conserved in bacteria
EC958_RS12420	COG3279	Response regulator of the LytR AlgR family
EC958_RS12425	COG3275	phosphorelay sensor kinase activity
EC958_RS12430	COG0789	Transcriptional regulator
EC958_RS12440	COG1174	glycine betaine transport
EC958_RS12445	COG1125	glycine betaine transport
EC958_RS12450	COG1174	glycine betaine transport
EC958_RS12455	COG1732	Glycine betaine
EC958_RS12460	COG1472	Belongs to the glycosyl hydrolase 3 family
EC958_RS12465	COG0277	FAD linked oxidase domain protein
EC958_RS12470	COG1686	Belongs to the peptidase S11 family
EC958_RS12480	COG0586	Pfam SNARE associated Golgi protein
EC958_RS12485	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS12500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EC958_RS12510	COG1346	cytolysis
EC958_RS12520	COG2949	membrane
EC958_RS12530	COG0493	'glutamate synthase
EC958_RS12535	COG0167	dihydroorotate dehydrogenase activity
EC958_RS12535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EC958_RS12540	COG4211	Belongs to the binding-protein-dependent transport system permease family
EC958_RS12550	COG1879	ABC-type sugar transport system periplasmic component
EC958_RS12555	COG1609	Transcriptional regulator
EC958_RS12565	COG2311	Membrane
EC958_RS12585	COG4771	TonB-dependent receptor
EC958_RS12595	COG0833	amino acid
EC958_RS12600	COG0583	DNA-binding transcription factor activity
EC958_RS12605	COG2855	membrane
EC958_RS12615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS12615	COG1522	sequence-specific DNA binding
EC958_RS12625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC958_RS12630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EC958_RS12635	COG2313	pseudouridylate synthase activity
EC958_RS12640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS12645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS12645	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EC958_RS12645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS12650	COG1105	Belongs to the carbohydrate kinase PfkB family
EC958_RS12655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS12655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS12660	COG2814	Major facilitator Superfamily
EC958_RS12675	COG0246	Mannitol dehydrogenase
EC958_RS12680	COG0523	cobalamin synthesis protein
EC958_RS12685	COG0671	phosphoesterase, PA-phosphatase related
EC958_RS12690	COG0791	NLP P60 protein
EC958_RS12695	COG2200	EAL domain
EC958_RS12700	COG4166	transmembrane transport
EC958_RS12705	COG4174	ABC transporter (Permease)
EC958_RS12710	COG4239	(ABC) transporter, permease
EC958_RS12715	COG4172	Belongs to the ABC transporter superfamily
EC958_RS12725	COG2814	Major facilitator Superfamily
EC958_RS12730	COG1187	pseudouridine synthase activity
EC958_RS12735	COG1061	Type III restriction enzyme res subunit
EC958_RS12755	COG3083	sulfuric ester hydrolase activity
EC958_RS12790	COG2197	response regulator
EC958_RS12795	COG4235	cytochrome complex assembly
EC958_RS12795	COG3088	subunit of a heme lyase
EC958_RS12800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC958_RS12805	COG1138	Cytochrome C-type biogenesis protein
EC958_RS12815	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC958_RS12820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC958_RS12825	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC958_RS12830	COG4133	protoheme IX ABC transporter activity
EC958_RS12835	COG3005	denitrification pathway
EC958_RS12840	COG3043	anaerobic respiration
EC958_RS12845	COG0348	domain, Protein
EC958_RS12850	COG0437	4 iron, 4 sulfur cluster binding
EC958_RS12860	COG3062	negative regulation of establishment of protein localization
EC958_RS12865	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS12865	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS12885	COG4615	Cyclic peptide transporter
EC958_RS12890	COG3145	DNA-N1-methyladenine dioxygenase activity
EC958_RS12895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC958_RS12895	COG2169	Transcriptional regulator
EC958_RS12900	COG1477	protein flavinylation
EC958_RS12920	COG0642	Histidine kinase
EC958_RS12920	COG2198	Histidine kinase
EC958_RS12925	COG2197	response regulator
EC958_RS12930	COG0784	Response regulator, receiver
EC958_RS12930	COG2205	protein histidine kinase activity
EC958_RS12935	COG3852	Histidine kinase
EC958_RS12940	COG2204	response regulator
EC958_RS12945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EC958_RS12950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC958_RS12955	COG2031	fatty acid transporter
EC958_RS12960	COG0183	Belongs to the thiolase family
EC958_RS12965	COG4676	Protein conserved in bacteria
EC958_RS12970	COG5445	Predicted secreted protein (DUF2300)
EC958_RS12975	COG2373	Large extracellular alpha-helical protein
EC958_RS12980	COG3234	Protein of unknown function (DUF1175)
EC958_RS12985	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
EC958_RS12990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EC958_RS13000	COG3468	outer membrane autotransporter barrel domain protein
EC958_RS13010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC958_RS13015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC958_RS13020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC958_RS13025	COG3642	lipopolysaccharide core region biosynthetic process
EC958_RS13030	COG0584	glycerophosphoryl diester phosphodiesterase
EC958_RS13035	COG2271	Major facilitator Superfamily
EC958_RS13040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EC958_RS13050	COG0247	lactate metabolic process
EC958_RS13055	COG5464	transposase or invertase
EC958_RS13065	COG3836	Belongs to the HpcH HpaI aldolase family
EC958_RS13070	COG2271	Major facilitator Superfamily
EC958_RS13075	COG4948	Mandelate Racemase Muconate Lactonizing
EC958_RS13080	COG1414	Transcriptional regulator
EC958_RS13125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EC958_RS13145	COG0318	PFAM AMP-dependent synthetase and ligase
EC958_RS13155	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EC958_RS13170	COG1169	isochorismate synthase
EC958_RS13175	COG4575	ribosome binding
EC958_RS13180	COG2153	protein acetylation
EC958_RS13190	COG2304	oxidoreductase activity
EC958_RS13195	COG2234	aminopeptidase activity
EC958_RS13210	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC958_RS13215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EC958_RS13225	COG0839	Belongs to the complex I subunit 6 family
EC958_RS13240	COG1034	ATP synthesis coupled electron transport
EC958_RS13245	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EC958_RS13250	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EC958_RS13270	COG0583	DNA-binding transcription factor activity
EC958_RS13275	COG0436	Aminotransferase
EC958_RS13285	COG0471	metal ion transport
EC958_RS13285	COG0490	domain, Protein
EC958_RS13290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC958_RS13310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EC958_RS13315	COG0280	phosphate acetyltransferase
EC958_RS13315	COG0857	belongs to the CobB CobQ family
EC958_RS13320	COG1288	antiporter activity
EC958_RS13325	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EC958_RS13330	COG0622	Phosphoesterase
EC958_RS13335	COG0625	glutathione transferase activity
EC958_RS13340	COG0625	glutathione transferase activity
EC958_RS13345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EC958_RS13350	COG1090	epimerase
EC958_RS13355	COG4598	ABC transporter
EC958_RS13360	COG4160	amino acid transport
EC958_RS13365	COG4215	(ABC) transporter
EC958_RS13370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC958_RS13375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC958_RS13380	COG0163	prenyltransferase activity
EC958_RS13385	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EC958_RS13390	COG1286	toxin biosynthetic process
EC958_RS13395	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EC958_RS13400	COG0285	dihydrofolate synthase activity
EC958_RS13410	COG0586	Pfam SNARE associated Golgi protein
EC958_RS13420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EC958_RS13435	COG2814	Major facilitator Superfamily
EC958_RS13440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EC958_RS13455	COG3101	peptidyl-lysine hydroxylation
EC958_RS13460	COG0730	response to heat
EC958_RS13490	COG3539	Fimbrial protein
EC958_RS13495	COG3539	Fimbrial protein
EC958_RS13500	COG3539	Fimbrial protein
EC958_RS13505	COG3121	Chaperone
EC958_RS13510	COG3188	usher protein
EC958_RS13515	COG3539	Fimbrial protein
EC958_RS13520	COG2062	phosphohistidine phosphatase, SixA
EC958_RS13535	COG3691	Protein conserved in bacteria
EC958_RS13540	COG2067	long-chain fatty acid transport protein
EC958_RS13550	COG2116	formate transmembrane transporter activity
EC958_RS13620	COG0583	DNA-binding transcription factor activity
EC958_RS13625	COG2610	gluconate transmembrane transporter activity
EC958_RS13635	COG0477	Major facilitator Superfamily
EC958_RS13640	COG1566	PFAM secretion protein HlyD family protein
EC958_RS13645	COG2197	response regulator
EC958_RS13650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC958_RS13650	COG2205	protein histidine kinase activity
EC958_RS13650	COG2198	Histidine kinase
EC958_RS13650	COG0784	Response regulator, receiver
EC958_RS13655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EC958_RS13660	COG0679	Auxin Efflux Carrier
EC958_RS13665	COG0028	Belongs to the TPP enzyme family
EC958_RS13695	COG1560	Kdo2-lipid A biosynthetic process
EC958_RS13700	COG0436	Aminotransferase
EC958_RS13705	COG3275	phosphorelay sensor kinase activity
EC958_RS13710	COG3279	Response regulator of the LytR AlgR family
EC958_RS13715	COG2207	Transcriptional regulator
EC958_RS13720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS13720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS13720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EC958_RS13725	COG1363	Peptidase, m42
EC958_RS13730	COG0006	proline dipeptidase activity
EC958_RS13735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS13740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS13770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EC958_RS13775	COG2199	diguanylate cyclase activity
EC958_RS13775	COG2200	EAL domain
EC958_RS13790	COG3415	Transposase
EC958_RS13795	COG3415	Transposase
EC958_RS13800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EC958_RS13825	COG0583	DNA-binding transcription factor activity
EC958_RS13835	COG2211	Major facilitator Superfamily
EC958_RS13840	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EC958_RS13850	COG0583	DNA-binding transcription factor activity
EC958_RS13855	COG0385	Bile acid
EC958_RS13860	COG3530	Putative quorum-sensing-regulated virulence factor
EC958_RS13880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EC958_RS13885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS13890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EC958_RS13895	COG2190	(PTS) system
EC958_RS13910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EC958_RS13915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EC958_RS13920	COG4208	sulfate ABC transporter
EC958_RS13925	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EC958_RS13930	COG4150	thiosulfate binding
EC958_RS13935	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS13945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS13945	COG1263	PTS System
EC958_RS13950	COG2837	iron assimilation
EC958_RS13970	COG0860	N-Acetylmuramoyl-L-alanine amidase
EC958_RS13980	COG2207	Transcriptional regulator
EC958_RS13985	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EC958_RS13990	COG4816	utilization protein
EC958_RS14000	COG4303	Ethanolamine ammonia lyase large subunit
EC958_RS14005	COG4819	ethanolamine utilization protein
EC958_RS14010	COG3192	ethanolamine utilization protein
EC958_RS14015	COG1454	alcohol dehydrogenase
EC958_RS14020	COG4820	ethanolamine utilization protein (EutJ)
EC958_RS14025	COG1012	belongs to the aldehyde dehydrogenase family
EC958_RS14030	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EC958_RS14035	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EC958_RS14040	COG0280	phosphate acetyltransferase
EC958_RS14045	COG4812	Cobalamin adenosyltransferase
EC958_RS14050	COG4766	ethanolamine catabolic process
EC958_RS14055	COG4917	ethanolamine utilization protein
EC958_RS14060	COG4810	utilization protein
EC958_RS14065	COG0281	malic enzyme
EC958_RS14065	COG0280	phosphate acetyltransferase
EC958_RS14070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EC958_RS14075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EC958_RS14080	COG5342	invasion associated locus B
EC958_RS14090	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS14090	COG0493	'glutamate synthase
EC958_RS14095	COG3850	Histidine kinase
EC958_RS14100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC958_RS14110	COG1393	Belongs to the ArsC family
EC958_RS14125	COG0400	carboxylic ester hydrolase activity
EC958_RS14135	COG2321	neutral zinc metallopeptidase
EC958_RS14150	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EC958_RS14160	COG2716	regulation of RNA biosynthetic process
EC958_RS14165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EC958_RS14170	COG0628	permease
EC958_RS14175	COG4783	chaperone-mediated protein folding
EC958_RS14180	COG1393	Belongs to the ArsC family
EC958_RS14190	COG2233	PERMEase
EC958_RS14205	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EC958_RS14210	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EC958_RS14215	COG0248	Ppx GppA phosphatase
EC958_RS14220	COG2200	EAL domain
EC958_RS14235	COG3133	Outer membrane lipoprotein
EC958_RS14250	COG0516	GMP reductase activity
EC958_RS14250	COG0517	IMP dehydrogenase activity
EC958_RS14275	COG1645	bacterial-type flagellum-dependent swarming motility
EC958_RS14290	COG2976	Protein conserved in bacteria
EC958_RS14320	COG4953	penicillin-binding protein 1C
EC958_RS14325	COG2373	Large extracellular alpha-helical protein
EC958_RS14330	COG2897	thiosulfate sulfurtransferase activity
EC958_RS14345	COG2975	iron-sulfur cluster assembly
EC958_RS14350	COG0633	Ferredoxin
EC958_RS14370	COG0822	iron-sulfur transferase activity
EC958_RS14390	COG0483	inositol monophosphate 1-phosphatase activity
EC958_RS14395	COG1073	alpha beta
EC958_RS14400	COG3711	transcriptional antiterminator
EC958_RS14405	COG2814	Major facilitator Superfamily
EC958_RS14410	COG2259	Doxx family
EC958_RS14415	COG2017	converts alpha-aldose to the beta-anomer
EC958_RS14420	COG1063	alcohol dehydrogenase
EC958_RS14425	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC958_RS14430	COG1129	ABC transporter
EC958_RS14435	COG1879	ABC-type sugar transport system periplasmic component
EC958_RS14440	COG0457	Tetratricopeptide repeat
EC958_RS14445	COG1940	carbohydrate kinase activity
EC958_RS14455	COG1017	nitric oxide dioxygenase activity
EC958_RS14455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC958_RS14460	COG0347	Belongs to the P(II) protein family
EC958_RS14465	COG2204	response regulator
EC958_RS14470	COG3170	Tfp pilus assembly protein FimV
EC958_RS14475	COG2205	protein histidine kinase activity
EC958_RS14490	COG0590	tRNA wobble adenosine to inosine editing
EC958_RS14495	COG0560	Phosphoserine phosphatase
EC958_RS14500	COG1737	Transcriptional regulator
EC958_RS14505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS14525	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EC958_RS14545	COG0681	Belongs to the peptidase S26 family
EC958_RS14555	COG3086	response to oxidative stress
EC958_RS14560	COG3026	antisigma factor binding
EC958_RS14565	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EC958_RS14570	COG1595	DNA-templated transcription, initiation
EC958_RS14580	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EC958_RS14590	COG0513	Belongs to the DEAD box helicase family
EC958_RS14595	COG0583	DNA-binding transcription factor activity
EC958_RS14615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC958_RS14625	COG3118	belongs to the thioredoxin family
EC958_RS14630	COG3148	PFAM DTW domain containing protein
EC958_RS14635	COG0045	succinate-CoA ligase (ADP-forming) activity
EC958_RS14635	COG1042	CoA-binding domain protein
EC958_RS14635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC958_RS14640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC958_RS14645	COG5544	Lipoprotein
EC958_RS14650	COG0477	Major facilitator Superfamily
EC958_RS14675	COG0542	response to heat
EC958_RS14685	COG0564	pseudouridine synthase activity
EC958_RS14690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC958_RS14700	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EC958_RS14705	COG0077	Prephenate dehydratase
EC958_RS14705	COG1605	Chorismate mutase
EC958_RS14710	COG0287	Prephenate dehydrogenase
EC958_RS14710	COG1605	Chorismate mutase
EC958_RS14715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EC958_RS14730	COG2199	diguanylate cyclase activity
EC958_RS14735	COG2885	chlorophyll binding
EC958_RS14760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EC958_RS14765	COG4137	Cytochrome C assembly protein
EC958_RS14770	COG4536	flavin adenine dinucleotide binding
EC958_RS14785	COG0497	DNA recombination
EC958_RS14790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC958_RS14800	COG2867	negative regulation of translational initiation
EC958_RS14820	COG1012	belongs to the aldehyde dehydrogenase family
EC958_RS14825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EC958_RS14830	COG1113	amino acid transport
EC958_RS14835	COG1802	Transcriptional regulator
EC958_RS14840	COG1652	LysM domain
EC958_RS14845	COG0401	homolog of Blt101
EC958_RS14850	COG0640	Transcriptional regulator
EC958_RS14855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EC958_RS14860	COG2916	Histone family protein nucleoid-structuring protein H-NS
EC958_RS14875	COG4575	ribosome binding
EC958_RS14880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EC958_RS14890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC958_RS14895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC958_RS14900	COG4175	Glycine betaine
EC958_RS14905	COG4176	ABC-type proline glycine betaine transport system permease component
EC958_RS14910	COG2113	Glycine betaine
EC958_RS14915	COG2814	Major facilitator Superfamily
EC958_RS14920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EC958_RS14930	COG1846	Transcriptional regulator
EC958_RS14935	COG1566	PFAM secretion protein HlyD family protein
EC958_RS14940	COG2814	Major facilitator Superfamily
EC958_RS14965	COG1238	metal cluster binding
EC958_RS14970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC958_RS15005	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EC958_RS15030	COG1546	Belongs to the CinA family
EC958_RS15040	COG2951	lytic endotransglycosylase activity
EC958_RS15045	COG3730	PTS system glucitol sorbitol-specific
EC958_RS15050	COG3732	PTS system glucitol sorbitol-specific
EC958_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS15065	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS15070	COG1349	DNA-binding transcription factor activity
EC958_RS15075	COG0517	IMP dehydrogenase activity
EC958_RS15075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EC958_RS15095	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EC958_RS15100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS15115	COG5499	transcription regulator containing HTH domain
EC958_RS15120	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EC958_RS15130	COG3260	NADH ubiquinone oxidoreductase 20
EC958_RS15135	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC958_RS15140	COG3261	NADH dehydrogenase
EC958_RS15140	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EC958_RS15145	COG0650	Formate hydrogenlyase subunit 4
EC958_RS15150	COG0651	ATP synthesis coupled electron transport
EC958_RS15155	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS15170	COG0375	protein maturation
EC958_RS15175	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EC958_RS15180	COG0298	carbon dioxide binding
EC958_RS15185	COG0409	Hydrogenase expression formation protein
EC958_RS15190	COG0309	Hydrogenase expression formation protein (HypE)
EC958_RS15195	COG3604	Transcriptional regulator
EC958_RS15210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EC958_RS15215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EC958_RS15220	COG1349	DNA-binding transcription factor activity
EC958_RS15225	COG2084	Dehydrogenase
EC958_RS15230	COG3395	kinase activity
EC958_RS15235	COG0235	Class ii aldolase
EC958_RS15240	COG3622	Belongs to the hyi family
EC958_RS15245	COG2610	gluconate transmembrane transporter activity
EC958_RS15260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EC958_RS15265	COG1388	LysM domain
EC958_RS15265	COG4942	peptidase
EC958_RS15280	COG0585	pseudouridine synthase activity
EC958_RS15320	COG2234	aminopeptidase activity
EC958_RS15345	COG0720	synthase
EC958_RS15350	COG0644	oxidoreductase
EC958_RS15355	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EC958_RS15360	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EC958_RS15365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EC958_RS15370	COG2086	electron transfer activity
EC958_RS15375	COG0477	Major facilitator Superfamily
EC958_RS15380	COG0277	FAD linked oxidase domain protein
EC958_RS15385	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS15390	COG2223	nitrite transmembrane transporter activity
EC958_RS15395	COG1070	Carbohydrate kinase
EC958_RS15425	COG0602	queuosine metabolic process
EC958_RS15435	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EC958_RS15450	COG3956	TIGRFAM MazG family protein
EC958_RS15455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC958_RS15465	COG2205	protein histidine kinase activity
EC958_RS15465	COG3437	response regulator, receiver
EC958_RS15465	COG3850	Histidine kinase
EC958_RS15465	COG4999	Histidine kinase
EC958_RS15470	COG4948	Mandelate Racemase Muconate Lactonizing
EC958_RS15475	COG4948	Mandelate Racemase Muconate Lactonizing
EC958_RS15480	COG2271	Major facilitator Superfamily
EC958_RS15485	COG0716	FMN binding
EC958_RS15490	COG0564	pseudouridine synthase activity
EC958_RS15495	COG3098	single-species biofilm formation
EC958_RS15515	COG1611	Belongs to the LOG family
EC958_RS15520	COG0814	amino acid
EC958_RS15525	COG1760	l-serine dehydratase
EC958_RS15535	COG1454	alcohol dehydrogenase
EC958_RS15540	COG0235	Class ii aldolase
EC958_RS15545	COG0738	Major facilitator superfamily
EC958_RS15555	COG1070	Carbohydrate kinase
EC958_RS15565	COG1349	DNA-binding transcription factor activity
EC958_RS15575	COG2363	Small membrane protein
EC958_RS15580	COG0583	DNA-binding transcription factor activity
EC958_RS15590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EC958_RS15595	COG2166	iron-sulfur cluster assembly
EC958_RS15600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EC958_RS15605	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EC958_RS15645	COG2885	chlorophyll binding
EC958_RS15720	COG4584	PFAM Integrase catalytic
EC958_RS15725	COG1484	DNA-dependent DNA replication
EC958_RS15785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EC958_RS15790	COG1263	PTS System
EC958_RS15790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS15795	COG3711	transcriptional antiterminator
EC958_RS15800	COG0860	N-Acetylmuramoyl-L-alanine amidase
EC958_RS15805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EC958_RS15805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EC958_RS15810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EC958_RS15815	COG1074	ATP-dependent DNA helicase activity
EC958_RS15820	COG1025	Belongs to the peptidase M16 family
EC958_RS15825	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EC958_RS15830	COG4967	type IV pilus modification protein PilV
EC958_RS15840	COG4795	General secretion pathway protein
EC958_RS15845	COG2165	general secretion pathway protein
EC958_RS15860	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
EC958_RS15885	COG0861	Integral membrane protein TerC family
EC958_RS15895	COG0667	Aldo Keto reductase
EC958_RS15910	COG1609	Transcriptional regulator
EC958_RS15920	COG0583	DNA-binding transcription factor activity
EC958_RS15925	COG1794	racemase activity, acting on amino acids and derivatives
EC958_RS15930	COG2814	Major facilitator Superfamily
EC958_RS15935	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS15945	COG0183	Belongs to the thiolase family
EC958_RS15950	COG0814	amino acid
EC958_RS15960	COG4942	peptidase
EC958_RS15965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EC958_RS15970	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EC958_RS15975	COG2080	2 iron, 2 sulfur cluster binding
EC958_RS15980	COG3829	transcription factor binding
EC958_RS15985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EC958_RS15990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EC958_RS15995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EC958_RS16005	COG0549	Belongs to the carbamate kinase family
EC958_RS16010	COG3608	succinylglutamate desuccinylase aspartoacylase
EC958_RS16010	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EC958_RS16015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EC958_RS16020	COG2068	MobA-Related Protein
EC958_RS16025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS16025	COG0493	'glutamate synthase
EC958_RS16030	COG0402	S-adenosylhomocysteine deaminase activity
EC958_RS16035	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EC958_RS16040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EC958_RS16040	COG2080	2 iron, 2 sulfur cluster binding
EC958_RS16045	COG2233	PERMEase
EC958_RS16050	COG0402	S-adenosylhomocysteine deaminase activity
EC958_RS16055	COG2252	PERMEase
EC958_RS16060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS16065	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS16065	COG0493	'glutamate synthase
EC958_RS16075	COG2233	PERMEase
EC958_RS16090	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EC958_RS16100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EC958_RS16105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EC958_RS16110	COG4974	Belongs to the 'phage' integrase family
EC958_RS16115	COG0716	FMN binding
EC958_RS16125	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EC958_RS16135	COG1272	protein, Hemolysin III
EC958_RS16145	COG2723	6-phospho-beta-galactosidase activity
EC958_RS16165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC958_RS16170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC958_RS16175	COG0006	proline dipeptidase activity
EC958_RS16190	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EC958_RS16195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC958_RS16215	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EC958_RS16215	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EC958_RS16230	COG2968	Membrane
EC958_RS16235	COG1279	arginine transmembrane transporter activity
EC958_RS16240	COG0668	transmembrane transport
EC958_RS16245	COG0191	fructose-bisphosphate aldolase activity
EC958_RS16285	COG1072	(Pantothenic acid kinase))
EC958_RS16295	COG1494	fructose-1,6-bisphosphatase
EC958_RS16300	COG1063	alcohol dehydrogenase
EC958_RS16305	COG2213	PTS system mannitol-specific
EC958_RS16310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS16315	COG0330	HflC and HflK could
EC958_RS16320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EC958_RS16325	COG0501	Belongs to the peptidase M48B family
EC958_RS16340	COG1166	arginine decarboxylase activity
EC958_RS16370	COG2814	Major facilitator Superfamily
EC958_RS16380	COG2356	endonuclease I
EC958_RS16385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EC958_RS16390	COG0189	ligase activity
EC958_RS16405	COG2805	Type II/IV secretion system protein
EC958_RS16410	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EC958_RS16415	COG0762	integral membrane protein
EC958_RS16425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EC958_RS16430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC958_RS16435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EC958_RS16440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EC958_RS16455	COG0252	asparaginase activity
EC958_RS16470	COG3171	Protein conserved in bacteria
EC958_RS16480	COG1194	a g-specific adenine glycosylase
EC958_RS16495	COG2211	Major facilitator Superfamily
EC958_RS16500	COG1982	Orn Lys Arg decarboxylase major
EC958_RS16505	COG1811	Na channel or pump
EC958_RS16515	COG0582	viral genome integration into host DNA
EC958_RS16640	COG3468	outer membrane autotransporter barrel domain protein
EC958_RS16650	COG2826	transposase and inactivated derivatives, IS30 family
EC958_RS16715	COG4771	TonB-dependent receptor
EC958_RS16750	COG0657	acetylesterase activity
EC958_RS16750	COG2755	lipolytic protein G-D-S-L family
EC958_RS16755	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
EC958_RS16760	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EC958_RS16770	COG2814	Major facilitator Superfamily
EC958_RS16780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC958_RS16800	COG3436	PFAM IS66 Orf2 family protein
EC958_RS16810	COG4372	Transposase
EC958_RS16850	COG4983	Phage plasmid primase, P4 family domain protein
EC958_RS16865	COG3468	outer membrane autotransporter barrel domain protein
EC958_RS16870	COG2020	methyltransferase activity
EC958_RS16895	COG2003	Belongs to the UPF0758 family
EC958_RS16950	COG4584	PFAM Integrase catalytic
EC958_RS17015	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EC958_RS17045	COG2165	general secretion pathway protein
EC958_RS17050	COG1459	type II secretion system
EC958_RS17055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EC958_RS17075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EC958_RS17080	COG3064	Membrane
EC958_RS17090	COG1620	l-lactate permease
EC958_RS17095	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EC958_RS17100	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EC958_RS17105	COG0247	lactate metabolic process
EC958_RS17110	COG0277	FAD linked oxidase domain protein
EC958_RS17115	COG0277	FAD linked oxidase domain protein
EC958_RS17120	COG2186	Transcriptional regulator
EC958_RS17155	COG0795	lipopolysaccharide-transporting ATPase activity
EC958_RS17160	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EC958_RS17170	COG2244	polysaccharide biosynthetic process
EC958_RS17175	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EC958_RS17180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EC958_RS17185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EC958_RS17190	COG0306	phosphate transporter
EC958_RS17195	COG0754	glutathionylspermidine amidase activity
EC958_RS17200	COG0625	glutathione transferase activity
EC958_RS17205	COG0298	carbon dioxide binding
EC958_RS17215	COG1773	rubredoxin
EC958_RS17220	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EC958_RS17225	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EC958_RS17230	COG5557	Pfam Polysulphide reductase, NrfD
EC958_RS17235	COG0437	4 iron, 4 sulfur cluster binding
EC958_RS17240	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EC958_RS17260	COG0667	Aldo Keto reductase
EC958_RS17270	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS17275	COG0848	biopolymer transport protein
EC958_RS17280	COG0811	peptide transport
EC958_RS17290	COG0626	cystathionine gamma-synthase activity
EC958_RS17295	COG0586	Pfam SNARE associated Golgi protein
EC958_RS17300	COG2207	Transcriptional regulator
EC958_RS17310	COG1979	alcohol dehydrogenase
EC958_RS17315	COG0656	L-ascorbic acid biosynthetic process
EC958_RS17325	COG4238	major outer membrane lipoprotein
EC958_RS17330	COG1032	radical SAM domain protein
EC958_RS17335	COG2186	Transcriptional regulator
EC958_RS17340	COG0246	Mannitol dehydrogenase
EC958_RS17345	COG1063	alcohol dehydrogenase
EC958_RS17350	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EC958_RS17370	COG2132	Multicopper oxidase
EC958_RS17375	COG0204	Acyl-transferase
EC958_RS17380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EC958_RS17385	COG4166	transmembrane transport
EC958_RS17390	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EC958_RS17395	COG3111	PFAM Bacterial OB fold (BOF) protein
EC958_RS17400	COG0745	RESPONSE REGULATOR receiver
EC958_RS17405	COG0642	Histidine kinase
EC958_RS17425	COG2249	NAD(P)H dehydrogenase (quinone) activity
EC958_RS17430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EC958_RS17435	COG1737	Transcriptional regulator
EC958_RS17445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC958_RS17450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC958_RS17455	COG1120	ATPase activity
EC958_RS17465	COG4774	siderophore transport
EC958_RS17470	COG0187	DNA topoisomerase II activity
EC958_RS17475	COG3150	esterase
EC958_RS17480	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EC958_RS17485	COG3151	Protein conserved in bacteria
EC958_RS17490	COG0494	nUDIX hydrolase
EC958_RS17495	COG1538	Outer membrane efflux protein
EC958_RS17510	COG0754	glutathionylspermidine amidase activity
EC958_RS17520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EC958_RS17530	COG3384	dioxygenase
EC958_RS17545	COG3539	Fimbrial protein
EC958_RS17550	COG3188	usher protein
EC958_RS17555	COG3121	Chaperone
EC958_RS17560	COG3539	Fimbrial protein
EC958_RS17580	COG1585	Membrane protein implicated in regulation of membrane protease activity
EC958_RS17585	COG2268	Band 7 protein
EC958_RS17605	COG3025	triphosphatase activity
EC958_RS17615	COG4991	sh3 domain protein
EC958_RS17630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EC958_RS17645	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EC958_RS17650	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EC958_RS17655	COG0471	metal ion transport
EC958_RS17665	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EC958_RS17670	COG0358	DNA primase activity
EC958_RS17675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EC958_RS17690	COG2375	cellular response to nickel ion
EC958_RS17695	COG1695	Transcriptional regulator
EC958_RS17700	COG0840	transmembrane signaling receptor activity
EC958_RS17710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EC958_RS17715	COG1609	Transcriptional regulator
EC958_RS17720	COG3250	beta-galactosidase activity
EC958_RS17725	COG2731	YhcH YjgK YiaL family protein
EC958_RS17730	COG0531	amino acid
EC958_RS17740	COG3408	Glycogen debranching enzyme
EC958_RS17740	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EC958_RS17745	COG0446	pyridine nucleotide-disulphide oxidoreductase
EC958_RS17745	COG1902	pentaerythritol trinitrate reductase activity
EC958_RS17750	COG5499	transcription regulator containing HTH domain
EC958_RS17755	COG4680	protein conserved in bacteria
EC958_RS17770	COG1451	nucleotide metabolic process
EC958_RS17775	COG2949	membrane
EC958_RS17780	COG0673	inositol 2-dehydrogenase activity
EC958_RS17785	COG0861	Integral membrane protein TerC family
EC958_RS17800	COG2721	sulfolactate sulfo-lyase activity
EC958_RS17810	COG2271	Major facilitator Superfamily
EC958_RS17815	COG2186	Transcriptional regulator
EC958_RS17820	COG0586	Pfam SNARE associated Golgi protein
EC958_RS17830	COG1422	Protein of unknown function (DUF1090)
EC958_RS17835	COG4575	ribosome binding
EC958_RS17840	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EC958_RS17850	COG2259	Doxx family
EC958_RS17855	COG0435	Glutathione S-transferase
EC958_RS17865	COG3152	Membrane
EC958_RS17870	COG0583	DNA-binding transcription factor activity
EC958_RS17875	COG1741	Belongs to the pirin family
EC958_RS17910	COG1760	l-serine dehydratase
EC958_RS17915	COG0251	oxidation-reduction process
EC958_RS17920	COG1882	Formate acetyltransferase
EC958_RS17925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EC958_RS17935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EC958_RS17940	COG0583	DNA-binding transcription factor activity
EC958_RS17950	COG1929	Belongs to the glycerate kinase type-1 family
EC958_RS17955	COG2084	Dehydrogenase
EC958_RS17965	COG2271	Major facilitator Superfamily
EC958_RS17970	COG2721	sulfolactate sulfo-lyase activity
EC958_RS17975	COG2002	toxin-antitoxin pair type II binding
EC958_RS17985	COG1349	DNA-binding transcription factor activity
EC958_RS17995	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS18005	COG3716	PTS system mannose fructose sorbose family IID component
EC958_RS18010	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS18015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EC958_RS18020	COG2222	sugar isomerase
EC958_RS18030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS18035	COG3715	PTS system
EC958_RS18040	COG3716	PTS system mannose fructose sorbose family IID component
EC958_RS18045	COG0363	glucosamine-6-phosphate deaminase activity
EC958_RS18050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EC958_RS18070	COG2823	Periplasmic or secreted lipoprotein
EC958_RS18075	COG0701	Predicted permease
EC958_RS18080	COG0702	epimerase
EC958_RS18085	COG0693	protein deglycase activity
EC958_RS18100	COG3153	acetyltransferase
EC958_RS18105	COG3154	lipid carrier protein
EC958_RS18110	COG0826	peptidase U32
EC958_RS18115	COG0826	peptidase U32
EC958_RS18120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC958_RS18125	COG0814	amino acid
EC958_RS18135	COG0513	Belongs to the DEAD box helicase family
EC958_RS18170	COG0195	Participates in both transcription termination and antitermination
EC958_RS18190	COG2194	sulfuric ester hydrolase activity
EC958_RS18205	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EC958_RS18215	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EC958_RS18220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EC958_RS18230	COG1534	Rna-binding protein
EC958_RS18235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EC958_RS18240	COG2027	D-alanyl-D-alanine carboxypeptidase
EC958_RS18250	COG0697	spore germination
EC958_RS18265	COG0142	geranyltranstransferase activity
EC958_RS18270	COG3423	Transcriptional regulator
EC958_RS18280	COG5007	Belongs to the BolA IbaG family
EC958_RS18285	COG3113	response to antibiotic
EC958_RS18290	COG2854	intermembrane phospholipid transfer
EC958_RS18295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EC958_RS18300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EC958_RS18305	COG1127	ABC transporter
EC958_RS18310	COG0530	calcium, potassium:sodium antiporter activity
EC958_RS18315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EC958_RS18315	COG0517	IMP dehydrogenase activity
EC958_RS18320	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EC958_RS18325	COG3117	lipopolysaccharide transmembrane transporter activity
EC958_RS18330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EC958_RS18335	COG1137	ATPase activity
EC958_RS18340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EC958_RS18345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EC958_RS18360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS18365	COG0515	serine threonine protein kinase
EC958_RS18375	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EC958_RS18380	COG0784	Response regulator, receiver
EC958_RS18380	COG5002	protein histidine kinase activity
EC958_RS18380	COG2198	Histidine kinase
EC958_RS18385	COG1242	4 iron, 4 sulfur cluster binding
EC958_RS18390	COG0067	glutamate synthase
EC958_RS18390	COG0069	glutamate synthase activity
EC958_RS18390	COG0070	glutamate synthase
EC958_RS18395	COG0493	'glutamate synthase
EC958_RS18400	COG2731	YhcH YjgK YiaL family protein
EC958_RS18405	COG1940	carbohydrate kinase activity
EC958_RS18415	COG2814	Major facilitator Superfamily
EC958_RS18430	COG2969	positive regulation of protein catabolic process
EC958_RS18435	COG0625	glutathione transferase activity
EC958_RS18450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EC958_RS18455	COG3105	Protein conserved in bacteria
EC958_RS18460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC958_RS18465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC958_RS18485	COG2732	(Barnase) inhibitor
EC958_RS18505	COG0583	DNA-binding transcription factor activity
EC958_RS18510	COG0312	modulator of DNA gyrase
EC958_RS18515	COG3164	Protein of unknown function
EC958_RS18520	COG1530	ribonuclease E activity
EC958_RS18530	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EC958_RS18535	COG1792	Involved in formation and maintenance of cell shape
EC958_RS18540	COG1077	Cell shape determining protein MreB Mrl
EC958_RS18550	COG2199	diguanylate cyclase activity
EC958_RS18550	COG2200	EAL domain
EC958_RS18555	COG0604	alcohol dehydrogenase
EC958_RS18570	COG0511	ligase activity, forming carbon-carbon bonds
EC958_RS18575	COG0439	Biotin carboxylase
EC958_RS18585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS18590	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC958_RS18595	COG1129	ABC transporter
EC958_RS18600	COG1879	ABC-type sugar transport system periplasmic component
EC958_RS18610	COG1349	DNA-binding transcription factor activity
EC958_RS18615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS18620	COG3924	membrane
EC958_RS18625	COG4145	pantothenate transmembrane transporter activity
EC958_RS18635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EC958_RS18645	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EC958_RS18655	COG1309	transcriptional regulator
EC958_RS18660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC958_RS18665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC958_RS18680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC958_RS18685	COG4597	amino acid ABC transporter
EC958_RS18690	COG0765	amino acid transport
EC958_RS18695	COG1126	abc transporter atp-binding protein
EC958_RS18735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EC958_RS18750	COG0009	L-threonylcarbamoyladenylate synthase
EC958_RS18755	COG0551	DNA topoisomerase type I activity
EC958_RS18765	COG0758	DNA mediated transformation
EC958_RS18785	COG0569	domain protein
EC958_RS18795	COG3036	rescue of stalled ribosome
EC958_RS18800	COG0789	Transcriptional regulator
EC958_RS18840	COG0201	protein transport
EC958_RS18930	COG0089	rRNA binding
EC958_RS18955	COG3267	Type II secretory pathway component ExeA
EC958_RS18955	COG3409	Peptidoglycan-binding domain 1 protein
EC958_RS18960	COG3031	protein transport across the cell outer membrane
EC958_RS18965	COG1450	Type ii and iii secretion system protein
EC958_RS18970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EC958_RS18975	COG1459	type II secretion system
EC958_RS18980	COG2165	general secretion pathway protein
EC958_RS18985	COG2165	general secretion pathway protein
EC958_RS18990	COG2165	general secretion pathway protein
EC958_RS18995	COG4795	General secretion pathway protein
EC958_RS19000	COG3156	type II secretion system protein K
EC958_RS19005	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EC958_RS19010	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EC958_RS19020	COG2193	ferroxidase activity
EC958_RS19025	COG2906	2 iron, 2 sulfur cluster binding
EC958_RS19030	COG3979	chitinase
EC958_RS19070	COG2964	Protein conserved in bacteria
EC958_RS19075	COG0545	Peptidyl-prolyl cis-trans isomerase
EC958_RS19085	COG1047	Peptidyl-prolyl cis-trans
EC958_RS19090	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EC958_RS19105	COG0488	(ABC) transporter
EC958_RS19110	COG0429	hydrolase of the alpha beta-hydrolase fold
EC958_RS19120	COG3954	Phosphoribulokinase
EC958_RS19125	COG1765	OsmC-like protein
EC958_RS19135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC958_RS19140	COG1289	transmembrane transporter activity
EC958_RS19145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EC958_RS19150	COG0512	Glutamine amidotransferase of anthranilate synthase
EC958_RS19155	COG2184	nucleotidyltransferase activity
EC958_RS19165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EC958_RS19175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EC958_RS19180	COG2146	nitrite reductase [NAD(P)H] activity
EC958_RS19185	COG2116	formate transmembrane transporter activity
EC958_RS19200	COG0626	cystathionine gamma-synthase activity
EC958_RS19215	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EC958_RS19220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EC958_RS19225	COG3457	Alanine racemase
EC958_RS19235	COG2188	Transcriptional regulator
EC958_RS19240	COG0180	Tryptophanyl-tRNA synthetase
EC958_RS19250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EC958_RS19255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EC958_RS19260	COG3266	domain, Protein
EC958_RS19275	COG4796	Type ii and iii secretion system protein
EC958_RS19290	COG3166	PFAM Fimbrial assembly family protein
EC958_RS19295	COG4972	Pilus assembly protein
EC958_RS19300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EC958_RS19305	COG0494	nUDIX hydrolase
EC958_RS19315	COG1011	Hydrolase
EC958_RS19320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EC958_RS19330	COG0675	Transposase, IS605 OrfB family
EC958_RS19340	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EC958_RS19365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EC958_RS19370	COG2183	response to ionizing radiation
EC958_RS19375	COG1918	ferrous iron import across plasma membrane
EC958_RS19380	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EC958_RS19390	COG5464	transposase or invertase
EC958_RS19395	COG0596	Alpha beta hydrolase
EC958_RS19410	COG2610	gluconate transmembrane transporter activity
EC958_RS19415	COG1640	4-alpha-glucanotransferase
EC958_RS19420	COG0058	SHG alpha-glucan phosphorylase activity
EC958_RS19440	COG1349	DNA-binding transcription factor activity
EC958_RS19455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EC958_RS19470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EC958_RS19475	COG0058	SHG alpha-glucan phosphorylase activity
EC958_RS19500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EC958_RS19505	COG2095	MarC family integral membrane protein
EC958_RS19515	COG0514	ATP-dependent DNA helicase (RecQ)
EC958_RS19520	COG2610	gluconate transmembrane transporter activity
EC958_RS19525	COG3265	gluconokinase activity
EC958_RS19530	COG1609	Transcriptional regulator
EC958_RS19535	COG1741	Belongs to the pirin family
EC958_RS19540	COG0673	inositol 2-dehydrogenase activity
EC958_RS19550	COG1247	-acetyltransferase
EC958_RS19555	COG0405	Gamma-glutamyltransferase
EC958_RS19565	COG0584	glycerophosphoryl diester phosphodiesterase
EC958_RS19595	COG0410	ABC transporter
EC958_RS19600	COG0411	ABC transporter
EC958_RS19605	COG4177	L-phenylalanine transmembrane transporter activity
EC958_RS19610	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC958_RS19615	COG0683	leucine binding
EC958_RS19620	COG0456	acetyltransferase
EC958_RS19635	COG0683	leucine binding
EC958_RS19640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EC958_RS19645	COG2177	Part of the ABC transporter FtsEX involved in
EC958_RS19650	COG2884	Cell division ATP-binding protein ftsE
EC958_RS19655	COG0552	protein localization to endoplasmic reticulum
EC958_RS19660	COG0742	ribosomal rna small subunit methyltransferase
EC958_RS19665	COG3776	membrane
EC958_RS19675	COG3714	YhhN family
EC958_RS19690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EC958_RS19700	COG0477	Major facilitator Superfamily
EC958_RS19705	COG0628	permease
EC958_RS19710	COG2091	lysine biosynthetic process via aminoadipic acid
EC958_RS19715	COG0747	negative chemotaxis
EC958_RS19720	COG0601	transmembrane transport
EC958_RS19725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC958_RS19745	COG2188	Transcriptional regulator
EC958_RS19755	COG3414	Phosphotransferase system galactitol-specific IIB component
EC958_RS19760	COG3775	system Galactitol-specific IIC component
EC958_RS19775	COG0191	fructose-bisphosphate aldolase activity
EC958_RS19780	COG0842	Transport permease protein
EC958_RS19785	COG0842	Transport permease protein
EC958_RS19785	COG1129	ABC transporter
EC958_RS19790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC958_RS19800	COG2081	HI0933 family
EC958_RS19805	COG0306	phosphate transporter
EC958_RS19815	COG0589	response to stress
EC958_RS19820	COG3104	oligopeptide transport
EC958_RS19830	COG0339	signal peptide processing
EC958_RS19835	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EC958_RS19840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC958_RS19855	COG1393	Belongs to the ArsC family
EC958_RS19860	COG3065	identical protein binding
EC958_RS19865	COG2197	response regulator
EC958_RS19870	COG3720	iron ion transport
EC958_RS19875	COG4771	TonB-dependent receptor
EC958_RS19895	COG3721	Heme iron utilization protein
EC958_RS19905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC958_RS19915	COG1285	pathogenesis
EC958_RS19930	COG3247	response to pH
EC958_RS19935	COG2771	luxR family
EC958_RS19945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC958_RS19950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC958_RS19955	COG2207	Transcriptional regulator
EC958_RS19960	COG2207	Transcriptional regulator
EC958_RS19965	COG0076	glutamate decarboxylase activity
EC958_RS19970	COG1858	cytochrome C peroxidase
EC958_RS19980	COG2197	response regulator
EC958_RS19985	COG0583	DNA-binding transcription factor activity
EC958_RS19990	COG1295	ribonuclease BN
EC958_RS19995	COG0477	Major facilitator Superfamily
EC958_RS20000	COG2982	Protein involved in outer membrane biogenesis
EC958_RS20005	COG2200	EAL domain
EC958_RS20015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS20020	COG0612	Peptidase, M16
EC958_RS20030	COG2199	diguanylate cyclase activity
EC958_RS20030	COG2200	EAL domain
EC958_RS20035	COG3118	belongs to the thioredoxin family
EC958_RS20035	COG0457	Tetratricopeptide repeat
EC958_RS20040	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EC958_RS20045	COG1215	transferase activity, transferring glycosyl groups
EC958_RS20050	COG1215	transferase activity, transferring glycosyl groups
EC958_RS20075	COG2194	sulfuric ester hydrolase activity
EC958_RS20100	COG0814	amino acid
EC958_RS20105	COG4608	Belongs to the ABC transporter superfamily
EC958_RS20110	COG0444	Belongs to the ABC transporter superfamily
EC958_RS20115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC958_RS20120	COG0601	transmembrane transport
EC958_RS20130	COG0747	negative chemotaxis
EC958_RS20145	COG2194	sulfuric ester hydrolase activity
EC958_RS20150	COG2223	nitrite transmembrane transporter activity
EC958_RS20155	COG5571	outer membrane autotransporter
EC958_RS20160	COG2818	Glycosylase
EC958_RS20165	COG0456	acetyltransferase
EC958_RS20170	COG0243	molybdopterin cofactor binding
EC958_RS20175	COG2885	chlorophyll binding
EC958_RS20190	COG2944	sequence-specific DNA binding
EC958_RS20195	COG1278	Cold shock
EC958_RS20220	COG3274	enterobacterial common antigen metabolic process
EC958_RS20225	COG4682	membrane
EC958_RS20230	COG4682	membrane
EC958_RS20235	COG1070	Carbohydrate kinase
EC958_RS20245	COG4213	ABC transporter substrate-binding protein
EC958_RS20255	COG4214	carbohydrate transport
EC958_RS20260	COG1609	Transcriptional regulator
EC958_RS20260	COG2207	Transcriptional regulator
EC958_RS20265	COG2992	FlgJ-related protein
EC958_RS20270	COG0366	Alpha amylase catalytic
EC958_RS20275	COG3977	Valine--pyruvate aminotransferase
EC958_RS20280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC958_RS20285	COG1414	Transcriptional regulator
EC958_RS20295	COG2731	YhcH YjgK YiaL family protein
EC958_RS20305	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EC958_RS20310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EC958_RS20315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EC958_RS20320	COG1070	Carbohydrate kinase
EC958_RS20325	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EC958_RS20330	COG3623	hexulose-6-phosphate isomerase
EC958_RS20335	COG0235	Class ii aldolase
EC958_RS20345	COG2211	Major facilitator Superfamily
EC958_RS20355	COG1012	belongs to the aldehyde dehydrogenase family
EC958_RS20365	COG1454	alcohol dehydrogenase
EC958_RS20370	COG3276	selenocysteine insertion sequence binding
EC958_RS20380	COG0625	glutathione transferase activity
EC958_RS20385	COG1566	PFAM secretion protein HlyD family protein
EC958_RS20395	COG2213	PTS system mannitol-specific
EC958_RS20395	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS20405	COG3722	fumarate hydratase activity
EC958_RS20425	COG5295	Hep Hag repeat protein
EC958_RS20430	COG1620	l-lactate permease
EC958_RS20435	COG2186	Transcriptional regulator
EC958_RS20445	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EC958_RS20450	COG1045	serine acetyltransferase
EC958_RS20465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EC958_RS20470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EC958_RS20480	COG4942	peptidase
EC958_RS20485	COG2861	carbohydrate metabolic process
EC958_RS20490	COG1216	Glycosyl transferase, family 2
EC958_RS20500	COG0156	8-amino-7-oxononanoate synthase activity
EC958_RS20510	COG0859	PFAM glycosyl transferase family 9
EC958_RS20515	COG0859	PFAM glycosyl transferase family 9
EC958_RS20520	COG3307	-O-antigen
EC958_RS20525	COG0859	PFAM glycosyl transferase family 9
EC958_RS20535	COG3642	lipopolysaccharide core region biosynthetic process
EC958_RS20540	COG1442	glycosyl transferase family 8
EC958_RS20545	COG1442	glycosyl transferase family 8
EC958_RS20550	COG0438	transferase activity, transferring glycosyl groups
EC958_RS20555	COG4641	Protein conserved in bacteria
EC958_RS20555	COG0438	transferase activity, transferring glycosyl groups
EC958_RS20560	COG0515	serine threonine protein kinase
EC958_RS20565	COG0438	transferase activity, transferring glycosyl groups
EC958_RS20570	COG0859	PFAM glycosyl transferase family 9
EC958_RS20575	COG1519	Transferase
EC958_RS20605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EC958_RS20630	COG1561	YicC-like family, N-terminal region
EC958_RS20635	COG2860	membrane
EC958_RS20640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EC958_RS20645	COG0194	GDP metabolic process
EC958_RS20655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC958_RS20660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC958_RS20670	COG0786	glutamate:sodium symporter activity
EC958_RS20675	COG2233	PERMEase
EC958_RS20680	COG2982	Protein involved in outer membrane biogenesis
EC958_RS20690	COG1940	carbohydrate kinase activity
EC958_RS20705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS20705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS20710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS20715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS20715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS20715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS20720	COG3711	transcriptional antiterminator
EC958_RS20725	COG1501	Belongs to the glycosyl hydrolase 31 family
EC958_RS20730	COG2211	Major facilitator Superfamily
EC958_RS20750	COG1609	Transcriptional regulator
EC958_RS20755	COG2271	Major facilitator Superfamily
EC958_RS20830	COG3344	reverse transcriptase
EC958_RS20930	COG3436	PFAM IS66 Orf2 family protein
EC958_RS20935	COG4372	Transposase
EC958_RS21030	COG3468	outer membrane autotransporter barrel domain protein
EC958_RS21050	COG2003	Belongs to the UPF0758 family
EC958_RS21095	COG0697	spore germination
EC958_RS21100	COG1464	Belongs to the NlpA lipoprotein family
EC958_RS21140	COG2252	PERMEase
EC958_RS21150	COG2271	Major facilitator Superfamily
EC958_RS21155	COG2271	Major facilitator Superfamily
EC958_RS21160	COG3851	Histidine kinase
EC958_RS21165	COG2197	response regulator
EC958_RS21180	COG0440	acetolactate synthase activity
EC958_RS21185	COG0028	Belongs to the TPP enzyme family
EC958_RS21195	COG2814	Major facilitator Superfamily
EC958_RS21200	COG0641	radical SAM
EC958_RS21210	COG2149	membrane
EC958_RS21215	COG3119	arylsulfatase activity
EC958_RS21220	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC958_RS21225	COG2207	Transcriptional regulator
EC958_RS21250	COG5645	(Lipo)protein
EC958_RS21255	COG0823	Involved in the tonB-independent uptake of proteins
EC958_RS21265	COG2271	Major facilitator Superfamily
EC958_RS21275	COG0800	Aldolase
EC958_RS21280	COG3734	2-keto-3-deoxy-galactonokinase
EC958_RS21285	COG2186	Transcriptional regulator
EC958_RS21295	COG0561	phosphatase activity
EC958_RS21300	COG3753	Protein conserved in bacteria
EC958_RS21310	COG0187	DNA topoisomerase II activity
EC958_RS21320	COG0592	DNA-directed DNA polymerase activity
EC958_RS21365	COG0814	amino acid
EC958_RS21375	COG0583	DNA-binding transcription factor activity
EC958_RS21380	COG2091	lysine biosynthetic process via aminoadipic acid
EC958_RS21385	COG0431	NADPH-dependent FMN reductase
EC958_RS21390	COG2252	PERMEase
EC958_RS21395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC958_RS21405	COG3196	Protein conserved in bacteria
EC958_RS21410	COG0363	glucosamine-6-phosphate deaminase activity
EC958_RS21415	COG2382	esterase
EC958_RS21420	COG4580	involved in the transport of maltose and maltodextrins
EC958_RS21425	COG2723	6-phospho-beta-galactosidase activity
EC958_RS21430	COG1263	PTS System
EC958_RS21430	COG2190	(PTS) system
EC958_RS21430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS21440	COG0704	Plays a role in the regulation of phosphate uptake
EC958_RS21445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EC958_RS21450	COG0581	inorganic phosphate transmembrane transporter activity
EC958_RS21455	COG0573	inorganic phosphate transmembrane transporter activity
EC958_RS21460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EC958_RS21470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EC958_RS21515	COG3312	ion transport
EC958_RS21530	COG0716	FMN binding
EC958_RS21535	COG1522	sequence-specific DNA binding
EC958_RS21560	COG1869	D-ribose catabolic process
EC958_RS21565	COG1129	ABC transporter
EC958_RS21570	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC958_RS21575	COG1879	ABC-type sugar transport system periplasmic component
EC958_RS21580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS21585	COG1609	Transcriptional regulator
EC958_RS21590	COG0477	Major facilitator Superfamily
EC958_RS21595	COG2186	Transcriptional regulator
EC958_RS21635	COG3085	chromosome segregation
EC958_RS21640	COG0606	chelatase, subunit chli
EC958_RS21655	COG3978	acetolactate synthase activity
EC958_RS21660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EC958_RS21670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EC958_RS21675	COG0583	DNA-binding transcription factor activity
EC958_RS21685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC958_RS21690	COG0210	DNA helicase
EC958_RS21705	COG3118	belongs to the thioredoxin family
EC958_RS21715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EC958_RS21725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC958_RS21730	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EC958_RS21735	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EC958_RS21740	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EC958_RS21745	COG1088	dTDP-glucose 4,6-dehydratase activity
EC958_RS21750	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC958_RS21755	COG0456	acetyltransferase
EC958_RS21760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EC958_RS21765	COG2244	polysaccharide biosynthetic process
EC958_RS21785	COG1113	amino acid transport
EC958_RS21810	COG0641	radical SAM
EC958_RS21815	COG3119	arylsulfatase activity
EC958_RS21825	COG3071	HemY protein
EC958_RS21830	COG2959	enzyme of heme biosynthesis
EC958_RS21835	COG1587	Uroporphyrinogen-III synthase
EC958_RS21845	COG3072	Adenylate cyclase
EC958_RS21855	COG5567	small periplasmic lipoprotein
EC958_RS21865	COG3159	Protein conserved in bacteria
EC958_RS21875	COG1011	Hydrolase
EC958_RS21880	COG0210	DNA helicase
EC958_RS21885	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
EC958_RS21890	COG3698	Phosphodiester glycosidase
EC958_RS21900	COG0598	Magnesium transport protein CorA
EC958_RS21915	COG2962	Rard protein
EC958_RS21920	COG2050	protein possibly involved in aromatic compounds catabolism
EC958_RS21925	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EC958_RS21930	COG0514	ATP-dependent DNA helicase (RecQ)
EC958_RS21935	COG1280	lysine exporter protein (LysE YggA)
EC958_RS21945	COG1280	lysine exporter protein (LysE YggA)
EC958_RS21950	COG2267	carboxylic ester hydrolase activity
EC958_RS21955	COG0561	phosphatase activity
EC958_RS21960	COG0697	spore germination
EC958_RS21965	COG0583	DNA-binding transcription factor activity
EC958_RS21980	COG1263	PTS System
EC958_RS21980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS21980	COG2190	(PTS) system
EC958_RS21985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EC958_RS21990	COG1737	Transcriptional regulator
EC958_RS21995	COG0583	DNA-binding transcription factor activity
EC958_RS22000	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EC958_RS22010	COG0549	Belongs to the carbamate kinase family
EC958_RS22015	COG1304	FMN binding
EC958_RS22020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EC958_RS22040	COG0412	Dienelactone hydrolase
EC958_RS22045	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EC958_RS22065	COG0800	Aldolase
EC958_RS22070	COG3734	2-keto-3-deoxy-galactonokinase
EC958_RS22075	COG1414	Transcriptional regulator
EC958_RS22080	COG1322	Protein conserved in bacteria
EC958_RS22090	COG3165	ubiquinone biosynthetic process from chorismate
EC958_RS22100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EC958_RS22110	COG0805	protein transport
EC958_RS22125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EC958_RS22130	COG0543	2 iron, 2 sulfur cluster binding
EC958_RS22150	COG1739	Uncharacterized protein family UPF0029
EC958_RS22155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EC958_RS22160	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EC958_RS22185	COG1763	Mo-molybdopterin cofactor biosynthetic process
EC958_RS22190	COG0746	molybdenum cofactor guanylyltransferase activity
EC958_RS22195	COG3084	Protein conserved in bacteria
EC958_RS22200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EC958_RS22205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EC958_RS22215	COG0204	Acyl-transferase
EC958_RS22225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EC958_RS22225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EC958_RS22240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC958_RS22250	COG2204	response regulator
EC958_RS22255	COG3852	Histidine kinase
EC958_RS22260	COG0174	glutamine synthetase
EC958_RS22270	COG1217	gtp-binding protein TYPA
EC958_RS22275	COG1349	DNA-binding transcription factor activity
EC958_RS22280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC958_RS22285	COG2084	Dehydrogenase
EC958_RS22290	COG3684	Belongs to the aldolase LacD family
EC958_RS22295	COG1063	alcohol dehydrogenase
EC958_RS22305	COG0477	Major facilitator Superfamily
EC958_RS22315	COG1011	Hydrolase
EC958_RS22330	COG0456	acetyltransferase
EC958_RS22340	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
EC958_RS22360	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EC958_RS22375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EC958_RS22385	COG2864	formate dehydrogenase
EC958_RS22390	COG0437	4 iron, 4 sulfur cluster binding
EC958_RS22460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EC958_RS22475	COG2258	MOSC domain
EC958_RS22480	COG2205	protein histidine kinase activity
EC958_RS22485	COG0745	RESPONSE REGULATOR receiver
EC958_RS22490	COG3678	ATP-independent chaperone mediated protein folding
EC958_RS22510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EC958_RS22530	COG3152	Membrane
EC958_RS22535	COG3691	Protein conserved in bacteria
EC958_RS22540	COG0589	response to stress
EC958_RS22550	COG1494	fructose-1,6-bisphosphatase
EC958_RS22560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EC958_RS22575	COG1575	Belongs to the MenA family. Type 1 subfamily
EC958_RS22590	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EC958_RS22595	COG1609	Transcriptional regulator
EC958_RS22600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EC958_RS22610	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EC958_RS22620	COG0626	cystathionine gamma-synthase activity
EC958_RS22625	COG0460	homoserine dehydrogenase
EC958_RS22625	COG0527	aspartate kinase activity
EC958_RS22635	COG0737	Belongs to the 5'-nucleotidase family
EC958_RS22640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EC958_RS22650	COG0697	spore germination
EC958_RS22655	COG3738	Protein conserved in bacteria
EC958_RS22665	COG0371	Dehydrogenase
EC958_RS22670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EC958_RS22675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS22675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EC958_RS22675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS22680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS22685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS22690	COG1882	Formate acetyltransferase
EC958_RS22695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC958_RS22700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC958_RS22705	COG2207	Transcriptional regulator
EC958_RS22710	COG2194	sulfuric ester hydrolase activity
EC958_RS22725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EC958_RS22740	COG0583	DNA-binding transcription factor activity
EC958_RS22750	COG1473	amidohydrolase
EC958_RS22755	COG0477	Major facilitator Superfamily
EC958_RS22760	COG1309	transcriptional regulator
EC958_RS22815	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EC958_RS22815	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EC958_RS22855	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EC958_RS22860	COG0250	Participates in transcription elongation, termination and antitermination
EC958_RS22895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EC958_RS22905	COG2104	thiamine diphosphate biosynthetic process
EC958_RS22910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EC958_RS22945	COG3068	Protein conserved in bacteria
EC958_RS22960	COG3678	ATP-independent chaperone mediated protein folding
EC958_RS22965	COG4191	Histidine kinase
EC958_RS22970	COG2204	response regulator
EC958_RS22975	COG0151	Belongs to the GarS family
EC958_RS23020	COG0456	acetyltransferase
EC958_RS23030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EC958_RS23035	COG2224	Isocitrate lyase
EC958_RS23045	COG1414	Transcriptional regulator
EC958_RS23050	COG0646	methionine synthase
EC958_RS23050	COG1410	methionine synthase
EC958_RS23060	COG1283	sodium-dependent phosphate transmembrane transporter activity
EC958_RS23110	COG1187	pseudouridine synthase activity
EC958_RS23120	COG0527	aspartate kinase activity
EC958_RS23145	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC958_RS23165	COG3833	ABC-type maltose transport systems, permease component
EC958_RS23170	COG1175	transmembrane transport
EC958_RS23175	COG2182	Extracellular solute-binding protein
EC958_RS23185	COG3842	ATPase activity
EC958_RS23215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EC958_RS23225	COG0534	Mate efflux family protein
EC958_RS23230	COG3237	CsbD-like
EC958_RS23235	COG0735	belongs to the Fur family
EC958_RS23240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EC958_RS23250	COG0604	alcohol dehydrogenase
EC958_RS23260	COG1914	H( )-stimulated, divalent metal cation uptake system
EC958_RS23265	COG1024	Enoyl-CoA hydratase
EC958_RS23275	COG1609	Transcriptional regulator
EC958_RS23280	COG0305	Participates in initiation and elongation during chromosome replication
EC958_RS23285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EC958_RS23290	COG3201	nicotinamide mononucleotide transporter
EC958_RS23300	COG1448	Aminotransferase
EC958_RS23305	COG0567	Dehydrogenase, E1 component
EC958_RS23315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC958_RS23320	COG0045	succinate-CoA ligase (ADP-forming) activity
EC958_RS23325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EC958_RS23330	COG0471	metal ion transport
EC958_RS23335	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EC958_RS23340	COG2204	response regulator
EC958_RS23350	COG3700	Belongs to the class B bacterial acid phosphatase family
EC958_RS23355	COG0432	Pfam Uncharacterised protein family UPF0047
EC958_RS23360	COG2315	Protein conserved in bacteria
EC958_RS23370	COG0629	single-stranded DNA binding
EC958_RS23380	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EC958_RS23385	COG2207	Transcriptional regulator
EC958_RS23390	COG0789	Transcriptional regulator
EC958_RS23395	COG2252	PERMEase
EC958_RS23400	COG0025	NhaP-type Na H and K H
EC958_RS23405	COG0583	DNA-binding transcription factor activity
EC958_RS23410	COG1380	Effector of murein hydrolase LrgA
EC958_RS23415	COG1346	cytolysis
EC958_RS23425	COG3162	membrane
EC958_RS23430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EC958_RS23440	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EC958_RS23445	COG0437	4 iron, 4 sulfur cluster binding
EC958_RS23450	COG3301	Polysulphide reductase, NrfD
EC958_RS23455	COG1138	Cytochrome C-type biogenesis protein
EC958_RS23460	COG3088	subunit of a heme lyase
EC958_RS23465	COG4235	cytochrome complex assembly
EC958_RS23470	COG1301	dicarboxylic acid transport
EC958_RS23475	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EC958_RS23480	COG4608	Belongs to the ABC transporter superfamily
EC958_RS23490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC958_RS23495	COG0601	transmembrane transport
EC958_RS23520	COG1289	transmembrane transporter activity
EC958_RS23525	COG1566	PFAM secretion protein HlyD family protein
EC958_RS23535	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EC958_RS23540	COG1940	carbohydrate kinase activity
EC958_RS23545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EC958_RS23550	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC958_RS23555	COG1129	ABC transporter
EC958_RS23560	COG1879	ABC-type sugar transport system periplasmic component
EC958_RS23565	COG1737	Transcriptional regulator
EC958_RS23570	COG0698	ribose 5-phosphate isomerase
EC958_RS23580	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EC958_RS23585	COG0456	acetyltransferase
EC958_RS23595	COG3454	Phosphonate metabolism
EC958_RS23600	COG4778	phosphonate C-P lyase system protein PhnL
EC958_RS23605	COG4107	phosphonate C-P lyase system protein PhnK
EC958_RS23610	COG3627	carbon phosphorus lyase activity
EC958_RS23615	COG3626	phosphonate metabolism
EC958_RS23620	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EC958_RS23625	COG3624	Phosphonate C-P lyase system protein PhnG
EC958_RS23630	COG2188	Transcriptional regulator
EC958_RS23635	COG3639	organic phosphonate transmembrane transporter activity
EC958_RS23640	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EC958_RS23650	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EC958_RS23655	COG2824	Alkylphosphonate utilization operon protein PhnA
EC958_RS23670	COG0477	Major facilitator Superfamily
EC958_RS23680	COG0642	Histidine kinase
EC958_RS23685	COG0745	RESPONSE REGULATOR receiver
EC958_RS23690	COG2194	sulfuric ester hydrolase activity
EC958_RS23695	COG0531	amino acid
EC958_RS23700	COG2207	Transcriptional regulator
EC958_RS23705	COG1982	Orn Lys Arg decarboxylase major
EC958_RS23710	COG2169	Transcriptional regulator
EC958_RS23720	COG1486	melibiose metabolic process
EC958_RS23725	COG3647	Membrane
EC958_RS23730	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EC958_RS23730	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EC958_RS23735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EC958_RS23745	COG4565	transcriptional regulatory protein
EC958_RS23750	COG3290	protein histidine kinase activity
EC958_RS23755	COG3592	Divergent 4Fe-4S mono-cluster
EC958_RS23760	COG2388	GCN5-related N-acetyl-transferase
EC958_RS23770	COG3121	Chaperone
EC958_RS23780	COG3210	domain, Protein
EC958_RS23780	COG3468	outer membrane autotransporter barrel domain protein
EC958_RS23795	COG2388	GCN5-related N-acetyl-transferase
EC958_RS23810	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EC958_RS23815	COG3104	oligopeptide transport
EC958_RS23820	COG1982	Orn Lys Arg decarboxylase major
EC958_RS23825	COG0531	amino acid
EC958_RS23830	COG3710	Transcriptional regulator
EC958_RS23840	COG1309	transcriptional regulator
EC958_RS23845	COG4232	protein-disulfide reductase activity
EC958_RS23855	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EC958_RS23860	COG1027	Aspartate ammonia-lyase
EC958_RS23865	COG3030	protein affecting phage T7 exclusion by the F plasmid
EC958_RS23870	COG0531	amino acid
EC958_RS23895	COG1509	lysine 2,3-aminomutase activity
EC958_RS23905	COG5510	response to toxic substance
EC958_RS23910	COG5510	response to toxic substance
EC958_RS23915	COG2076	Multidrug Resistance protein
EC958_RS23920	COG3040	lipid binding
EC958_RS23925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EC958_RS23940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EC958_RS23945	COG1053	succinate dehydrogenase
EC958_RS23955	COG0531	amino acid
EC958_RS23965	COG3264	Mechanosensitive ion channel
EC958_RS23965	COG1511	domain protein
EC958_RS24000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EC958_RS24005	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EC958_RS24005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EC958_RS24010	COG0802	atpase or kinase
EC958_RS24015	COG0860	N-Acetylmuramoyl-L-alanine amidase
EC958_RS24035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EC958_RS24040	COG0330	HflC and HflK could
EC958_RS24045	COG0330	HflC and HflK could
EC958_RS24050	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EC958_RS24065	COG0557	exoribonuclease II activity
EC958_RS24070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC958_RS24075	COG3789	protein conserved in bacteria
EC958_RS24080	COG1842	Phage shock protein A
EC958_RS24090	COG3766	membrane
EC958_RS24095	COG5463	Belongs to the UPF0441 family
EC958_RS24100	COG0754	glutathionylspermidine amidase activity
EC958_RS24105	COG1960	acyl-CoA dehydrogenase activity
EC958_RS24115	COG3650	response to hydrogen peroxide
EC958_RS24120	COG1073	alpha beta
EC958_RS24135	COG3037	sugar-specific permease SgaT UlaA
EC958_RS24140	COG3414	Phosphotransferase system galactitol-specific IIB component
EC958_RS24160	COG0235	Class ii aldolase
EC958_RS24185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EC958_RS24205	COG2271	Major facilitator Superfamily
EC958_RS24215	COG4670	ketone body catabolic process
EC958_RS24235	COG1309	transcriptional regulator
EC958_RS24240	COG3061	Opacity-associated protein A
EC958_RS24245	COG0545	Peptidyl-prolyl cis-trans isomerase
EC958_RS24250	COG1113	amino acid transport
EC958_RS24260	COG0697	spore germination
EC958_RS24265	COG0702	epimerase
EC958_RS24270	COG1733	regulation of RNA biosynthetic process
EC958_RS24275	COG0737	Belongs to the 5'-nucleotidase family
EC958_RS24280	COG1218	3'(2'),5'-bisphosphate nucleotidase
EC958_RS24285	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EC958_RS24295	COG1253	flavin adenine dinucleotide binding
EC958_RS24310	COG0729	surface antigen
EC958_RS24315	COG2911	Protein conserved in bacteria
EC958_RS24320	COG2105	PFAM AIG2 family protein
EC958_RS24325	COG2336	PFAM SpoVT AbrB
EC958_RS24330	COG2337	Toxic component of a toxin-antitoxin (TA) module
EC958_RS24335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EC958_RS24340	COG1879	ABC-type sugar transport system periplasmic component
EC958_RS24345	COG1129	ABC transporter
EC958_RS24350	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC958_RS24355	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC958_RS24365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EC958_RS24375	COG0312	modulator of DNA gyrase
EC958_RS24380	COG3783	Cytochrome b(562)
EC958_RS24385	COG0602	queuosine metabolic process
EC958_RS24390	COG1328	CTP reductase activity
EC958_RS24395	COG0366	Alpha amylase catalytic
EC958_RS24400	COG1263	PTS System
EC958_RS24400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC958_RS24405	COG1609	Transcriptional regulator
EC958_RS24410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EC958_RS24415	COG0251	oxidation-reduction process
EC958_RS24440	COG0251	oxidation-reduction process
EC958_RS24445	COG1028	Short-chain dehydrogenase reductase Sdr
EC958_RS24450	COG1309	transcriptional regulator
EC958_RS24455	COG2731	YhcH YjgK YiaL family protein
EC958_RS24470	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EC958_RS24475	COG0456	acetyltransferase
EC958_RS24480	COG4269	membrane
EC958_RS24490	COG2927	DNA polymerase III (CHI subunit)
EC958_RS24500	COG0795	lipopolysaccharide-transporting ATPase activity
EC958_RS24505	COG0795	lipopolysaccharide-transporting ATPase activity
EC958_RS24510	COG0433	COG0433 Predicted ATPase
EC958_RS24515	COG1064	alcohol dehydrogenase
EC958_RS24555	COG1414	Transcriptional regulator
EC958_RS24560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC958_RS24565	COG2721	sulfolactate sulfo-lyase activity
EC958_RS24570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EC958_RS24575	COG2271	Major facilitator Superfamily
EC958_RS24605	COG3436	PFAM IS66 Orf2 family protein
EC958_RS24610	COG4372	Transposase
EC958_RS24620	COG0738	Major facilitator superfamily
EC958_RS24630	COG1349	DNA-binding transcription factor activity
EC958_RS24670	COG3039	Transposase
EC958_RS24700	COG1120	ATPase activity
EC958_RS24705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC958_RS24710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC958_RS24715	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EC958_RS24720	COG4772	TonB-dependent receptor
EC958_RS24725	COG3712	iron ion homeostasis
EC958_RS24730	COG1595	DNA-templated transcription, initiation
EC958_RS24760	COG4372	Transposase
EC958_RS24765	COG3436	PFAM IS66 Orf2 family protein
EC958_RS24820	COG3468	outer membrane autotransporter barrel domain protein
EC958_RS24840	COG2003	Belongs to the UPF0758 family
EC958_RS24850	COG4584	PFAM Integrase catalytic
EC958_RS24855	COG1484	DNA-dependent DNA replication
EC958_RS24910	COG1401	restriction endodeoxyribonuclease activity
EC958_RS24940	COG2390	Transcriptional regulator
EC958_RS24950	COG2610	gluconate transmembrane transporter activity
EC958_RS24955	COG0129	dihydroxy-acid dehydratase activity
EC958_RS24960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC958_RS24965	COG1414	Transcriptional regulator
EC958_RS24970	COG1349	DNA-binding transcription factor activity
EC958_RS24975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EC958_RS24980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC958_RS24985	COG0434	BtpA family
EC958_RS24990	COG3775	system Galactitol-specific IIC component
EC958_RS24995	COG3414	Phosphotransferase system galactitol-specific IIB component
EC958_RS25000	COG1363	Peptidase, m42
EC958_RS25010	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EC958_RS25045	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
EC958_RS25050	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EC958_RS25085	COG4974	Belongs to the 'phage' integrase family
EC958_RS25100	COG3539	Fimbrial protein
EC958_RS25105	COG3121	Chaperone
EC958_RS25110	COG3188	usher protein
EC958_RS25115	COG3539	Fimbrial protein
EC958_RS25120	COG3539	Fimbrial protein
EC958_RS25125	COG3539	Fimbrial protein
EC958_RS25130	COG2610	gluconate transmembrane transporter activity
EC958_RS25145	COG0246	Mannitol dehydrogenase
EC958_RS25155	COG2186	Transcriptional regulator
EC958_RS25175	COG0583	DNA-binding transcription factor activity
EC958_RS25180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EC958_RS25185	COG0700	Nucleoside recognition
EC958_RS25190	COG3366	ferrous iron transmembrane transporter activity
EC958_RS25200	COG0477	Major facilitator Superfamily
EC958_RS25215	COG1924	4 iron, 4 sulfur cluster binding
EC958_RS25220	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
EC958_RS25225	COG2733	membrane
EC958_RS25230	COG2814	Major facilitator Superfamily
EC958_RS25240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC958_RS25245	COG5457	Domain of unknown function (DUF1127)
EC958_RS25255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EC958_RS25260	COG0732	type I restriction modification DNA specificity domain
EC958_RS25265	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EC958_RS25270	COG1715	Restriction endonuclease
EC958_RS25285	COG0523	cobalamin synthesis protein
EC958_RS25290	COG2879	small protein
EC958_RS25295	COG1966	Carbon starvation protein
EC958_RS25305	COG0840	transmembrane signaling receptor activity
EC958_RS25310	COG2271	Major facilitator Superfamily
EC958_RS25315	COG1802	Transcriptional regulator
EC958_RS25320	COG1063	alcohol dehydrogenase
EC958_RS25335	COG1484	DNA-dependent DNA replication
EC958_RS25350	COG2966	Psort location CytoplasmicMembrane, score
EC958_RS25355	COG2197	response regulator
EC958_RS25360	COG2197	response regulator
EC958_RS25365	COG4114	ferric iron reductase
EC958_RS25395	COG2813	Specifically methylates the guanine in position
EC958_RS25400	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EC958_RS25405	COG0456	acetyltransferase
EC958_RS25410	COG1011	Hydrolase
EC958_RS25420	COG2823	Periplasmic or secreted lipoprotein
EC958_RS25430	COG4667	esterase of the alpha-beta hydrolase superfamily
EC958_RS25435	COG0084	hydrolase, TatD family'
EC958_RS25440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC958_RS25445	COG1328	CTP reductase activity
EC958_RS25475	COG3550	peptidyl-serine autophosphorylation
EC958_RS25490	COG0560	Phosphoserine phosphatase
EC958_RS25495	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EC958_RS25500	COG3172	ATPase kinase involved in NAD metabolism
EC958_RS25500	COG1056	cytidyltransferase-related domain
EC958_RS25505	COG0488	(ABC) transporter
EC958_RS25510	COG0741	lytic transglycosylase activity
EC958_RS25530	COG2207	Transcriptional regulator
EC958_RS25530	COG3708	Transcriptional regulator
EC958_RS25535	COG3045	CreA protein
EC958_RS25540	COG0745	RESPONSE REGULATOR receiver
EC958_RS25545	COG2205	protein histidine kinase activity
EC958_RS25550	COG4452	Inner membrane protein CreD
EC958_RS25555	COG0745	RESPONSE REGULATOR receiver
EC958_RS25565	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EC958_RS25715	COG1475	DNA binding
EC958_RS26055	COG0577	efflux transmembrane transporter activity
EC958_RS26055	COG1136	(ABC) transporter
EC958_RS26075	COG0672	)-iron permease
EC958_RS26080	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EC958_RS26135	COG1695	Transcriptional regulator
EC958_RS26160	COG3173	Aminoglycoside phosphotransferase
EC958_RS26225	COG0697	spore germination
EC958_RS26260	COG1414	Transcriptional regulator
EC958_RS26320	COG5290	Psort location Cytoplasmic, score
EC958_RS26345	COG4372	Transposase
EC958_RS26350	COG3436	PFAM IS66 Orf2 family protein
EC958_RS28955	COG0604	alcohol dehydrogenase
EC958_RS29125	COG2116	formate transmembrane transporter activity
EC958_RS29425	COG2085	NADP oxidoreductase coenzyme F420-dependent
EC958_RS29460	COG3726	membrane protein affecting hemolysin expression
EC958_RS29755	COG4974	Belongs to the 'phage' integrase family
EC958_RS30080	COG3119	arylsulfatase activity
EC958_RS30195	COG3468	outer membrane autotransporter barrel domain protein