locus-tag	class	description
B9S25_RS00010	COG0592	DNA-directed DNA polymerase activity
B9S25_RS00020	COG0187	DNA topoisomerase II activity
B9S25_RS00025	COG3753	Protein conserved in bacteria
B9S25_RS00030	COG0561	phosphatase activity
B9S25_RS00040	COG2186	Transcriptional regulator
B9S25_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
B9S25_RS00050	COG0800	Aldolase
B9S25_RS00060	COG2271	Major facilitator Superfamily
B9S25_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
B9S25_RS00075	COG5645	(Lipo)protein
B9S25_RS00095	COG2188	Transcriptional regulator
B9S25_RS00110	COG2207	Transcriptional regulator
B9S25_RS00115	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9S25_RS00120	COG3119	arylsulfatase activity
B9S25_RS00130	COG2149	membrane
B9S25_RS00140	COG0641	radical SAM
B9S25_RS00145	COG2814	Major facilitator Superfamily
B9S25_RS00160	COG0028	Belongs to the TPP enzyme family
B9S25_RS00165	COG0440	acetolactate synthase activity
B9S25_RS00170	COG2197	response regulator
B9S25_RS00175	COG3851	Histidine kinase
B9S25_RS00180	COG2271	Major facilitator Superfamily
B9S25_RS00185	COG2271	Major facilitator Superfamily
B9S25_RS00195	COG2252	PERMEase
B9S25_RS00215	COG1464	Belongs to the NlpA lipoprotein family
B9S25_RS00220	COG0697	spore germination
B9S25_RS00225	COG2814	Major facilitator Superfamily
B9S25_RS00240	COG2211	Major facilitator Superfamily
B9S25_RS00245	COG1501	Belongs to the glycosyl hydrolase 31 family
B9S25_RS00250	COG2982	Protein involved in outer membrane biogenesis
B9S25_RS00255	COG2233	PERMEase
B9S25_RS00260	COG0786	glutamate:sodium symporter activity
B9S25_RS00270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B9S25_RS00275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9S25_RS00280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9S25_RS00290	COG0194	GDP metabolic process
B9S25_RS00300	COG2860	membrane
B9S25_RS00305	COG3645	SOS response
B9S25_RS00310	COG1561	YicC-like family, N-terminal region
B9S25_RS00335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B9S25_RS00365	COG1519	Transferase
B9S25_RS00370	COG0859	PFAM glycosyl transferase family 9
B9S25_RS00375	COG0438	transferase activity, transferring glycosyl groups
B9S25_RS00380	COG0515	serine threonine protein kinase
B9S25_RS00390	COG3642	lipopolysaccharide core region biosynthetic process
B9S25_RS00410	COG0859	PFAM glycosyl transferase family 9
B9S25_RS00415	COG0859	PFAM glycosyl transferase family 9
B9S25_RS00430	COG0156	8-amino-7-oxononanoate synthase activity
B9S25_RS00440	COG1216	Glycosyl transferase, family 2
B9S25_RS00445	COG2861	carbohydrate metabolic process
B9S25_RS00450	COG4942	peptidase
B9S25_RS00460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9S25_RS00465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B9S25_RS00480	COG1045	serine acetyltransferase
B9S25_RS00485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B9S25_RS00495	COG2186	Transcriptional regulator
B9S25_RS00500	COG1620	l-lactate permease
B9S25_RS00505	COG5295	Hep Hag repeat protein
B9S25_RS00530	COG3722	fumarate hydratase activity
B9S25_RS00540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS00540	COG2213	PTS system mannitol-specific
B9S25_RS00550	COG1566	PFAM secretion protein HlyD family protein
B9S25_RS00570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B9S25_RS00575	COG3209	COG3209 Rhs family protein
B9S25_RS00580	COG1413	lyase activity
B9S25_RS00585	COG3209	COG3209 Rhs family protein
B9S25_RS00590	COG0625	glutathione transferase activity
B9S25_RS00600	COG3276	selenocysteine insertion sequence binding
B9S25_RS00605	COG1454	alcohol dehydrogenase
B9S25_RS00610	COG1012	belongs to the aldehyde dehydrogenase family
B9S25_RS00620	COG1566	PFAM secretion protein HlyD family protein
B9S25_RS00625	COG0583	DNA-binding transcription factor activity
B9S25_RS00630	COG3713	MltA-interacting MipA family protein
B9S25_RS00640	COG0235	Class ii aldolase
B9S25_RS00645	COG3623	hexulose-6-phosphate isomerase
B9S25_RS00650	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B9S25_RS00655	COG1070	Carbohydrate kinase
B9S25_RS00660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B9S25_RS00665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B9S25_RS00670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B9S25_RS00675	COG2731	YhcH YjgK YiaL family protein
B9S25_RS00685	COG1414	Transcriptional regulator
B9S25_RS00690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS00695	COG3977	Valine--pyruvate aminotransferase
B9S25_RS00700	COG0366	Alpha amylase catalytic
B9S25_RS00705	COG2992	FlgJ-related protein
B9S25_RS00710	COG1609	Transcriptional regulator
B9S25_RS00710	COG2207	Transcriptional regulator
B9S25_RS00715	COG4214	carbohydrate transport
B9S25_RS00720	COG1129	ABC transporter
B9S25_RS00725	COG4213	ABC transporter substrate-binding protein
B9S25_RS00735	COG1070	Carbohydrate kinase
B9S25_RS00740	COG4682	membrane
B9S25_RS00745	COG4682	membrane
B9S25_RS00750	COG3274	enterobacterial common antigen metabolic process
B9S25_RS00775	COG1278	Cold shock
B9S25_RS00780	COG2944	sequence-specific DNA binding
B9S25_RS00795	COG2885	chlorophyll binding
B9S25_RS00800	COG0243	molybdopterin cofactor binding
B9S25_RS00805	COG0456	acetyltransferase
B9S25_RS00810	COG2818	Glycosylase
B9S25_RS00815	COG5571	outer membrane autotransporter
B9S25_RS00820	COG2223	nitrite transmembrane transporter activity
B9S25_RS00850	COG2194	sulfuric ester hydrolase activity
B9S25_RS00870	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS00880	COG0747	negative chemotaxis
B9S25_RS00890	COG0601	transmembrane transport
B9S25_RS00895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S25_RS00900	COG0444	Belongs to the ABC transporter superfamily
B9S25_RS00905	COG4608	Belongs to the ABC transporter superfamily
B9S25_RS00910	COG0814	amino acid
B9S25_RS00955	COG2194	sulfuric ester hydrolase activity
B9S25_RS00980	COG1215	transferase activity, transferring glycosyl groups
B9S25_RS00985	COG1215	transferase activity, transferring glycosyl groups
B9S25_RS00990	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B9S25_RS00995	COG0457	Tetratricopeptide repeat
B9S25_RS00995	COG3118	belongs to the thioredoxin family
B9S25_RS01000	COG2199	diguanylate cyclase activity
B9S25_RS01000	COG2200	EAL domain
B9S25_RS01010	COG0612	Peptidase, M16
B9S25_RS01020	COG2200	EAL domain
B9S25_RS01025	COG2982	Protein involved in outer membrane biogenesis
B9S25_RS01030	COG0477	Major facilitator Superfamily
B9S25_RS01035	COG1295	ribonuclease BN
B9S25_RS01040	COG0583	DNA-binding transcription factor activity
B9S25_RS01045	COG2197	response regulator
B9S25_RS01055	COG1858	cytochrome C peroxidase
B9S25_RS01060	COG0076	glutamate decarboxylase activity
B9S25_RS01070	COG2207	Transcriptional regulator
B9S25_RS01075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9S25_RS01080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9S25_RS01090	COG2771	luxR family
B9S25_RS01095	COG3247	response to pH
B9S25_RS01110	COG1285	pathogenesis
B9S25_RS01120	COG3065	identical protein binding
B9S25_RS01140	COG1393	Belongs to the ArsC family
B9S25_RS01145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B9S25_RS01150	COG0640	Transcriptional regulator
B9S25_RS01160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9S25_RS01165	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B9S25_RS01170	COG0339	signal peptide processing
B9S25_RS01180	COG3104	oligopeptide transport
B9S25_RS01190	COG0589	response to stress
B9S25_RS01200	COG0306	phosphate transporter
B9S25_RS01205	COG2081	HI0933 family
B9S25_RS01225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9S25_RS01230	COG1129	ABC transporter
B9S25_RS01230	COG0842	Transport permease protein
B9S25_RS01235	COG0842	Transport permease protein
B9S25_RS01245	COG1413	lyase activity
B9S25_RS01255	COG3209	COG3209 Rhs family protein
B9S25_RS01270	COG0444	Belongs to the ABC transporter superfamily
B9S25_RS01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S25_RS01280	COG0601	transmembrane transport
B9S25_RS01285	COG0747	negative chemotaxis
B9S25_RS01290	COG2091	lysine biosynthetic process via aminoadipic acid
B9S25_RS01295	COG0628	permease
B9S25_RS01310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B9S25_RS01325	COG3714	YhhN family
B9S25_RS01335	COG3776	membrane
B9S25_RS01340	COG0742	ribosomal rna small subunit methyltransferase
B9S25_RS01345	COG0552	protein localization to endoplasmic reticulum
B9S25_RS01350	COG2884	Cell division ATP-binding protein ftsE
B9S25_RS01355	COG2177	Part of the ABC transporter FtsEX involved in
B9S25_RS01360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9S25_RS01365	COG0683	leucine binding
B9S25_RS01370	COG0456	acetyltransferase
B9S25_RS01375	COG0683	leucine binding
B9S25_RS01380	COG0559	Belongs to the binding-protein-dependent transport system permease family
B9S25_RS01385	COG4177	L-phenylalanine transmembrane transporter activity
B9S25_RS01390	COG0411	ABC transporter
B9S25_RS01395	COG0410	ABC transporter
B9S25_RS01400	COG1653	transport
B9S25_RS01405	COG1175	transmembrane transport
B9S25_RS01415	COG3842	ATPase activity
B9S25_RS01420	COG0584	glycerophosphoryl diester phosphodiesterase
B9S25_RS01430	COG0405	Gamma-glutamyltransferase
B9S25_RS01455	COG3157	Type VI secretion system effector, Hcp
B9S25_RS01460	COG1247	-acetyltransferase
B9S25_RS01465	COG0673	inositol 2-dehydrogenase activity
B9S25_RS01470	COG1741	Belongs to the pirin family
B9S25_RS01475	COG1609	Transcriptional regulator
B9S25_RS01480	COG3265	gluconokinase activity
B9S25_RS01485	COG2610	gluconate transmembrane transporter activity
B9S25_RS01490	COG2095	MarC family integral membrane protein
B9S25_RS01495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B9S25_RS01520	COG0058	SHG alpha-glucan phosphorylase activity
B9S25_RS01525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B9S25_RS01545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B9S25_RS01560	COG1349	DNA-binding transcription factor activity
B9S25_RS01565	COG4650	regulator
B9S25_RS01570	COG1690	Belongs to the RtcB family
B9S25_RS01585	COG0058	SHG alpha-glucan phosphorylase activity
B9S25_RS01590	COG1640	4-alpha-glucanotransferase
B9S25_RS01595	COG2610	gluconate transmembrane transporter activity
B9S25_RS01615	COG5464	transposase or invertase
B9S25_RS01625	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B9S25_RS01630	COG1918	ferrous iron import across plasma membrane
B9S25_RS01635	COG2183	response to ionizing radiation
B9S25_RS01640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9S25_RS01660	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B9S25_RS01670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B9S25_RS01675	COG1011	Hydrolase
B9S25_RS01685	COG0494	nUDIX hydrolase
B9S25_RS01690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B9S25_RS01695	COG4972	Pilus assembly protein
B9S25_RS01700	COG3166	PFAM Fimbrial assembly family protein
B9S25_RS01715	COG4796	Type ii and iii secretion system protein
B9S25_RS01730	COG3266	domain, Protein
B9S25_RS01735	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B9S25_RS01740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B9S25_RS01745	COG0546	phosphoglycolate phosphatase activity
B9S25_RS01750	COG0180	Tryptophanyl-tRNA synthetase
B9S25_RS01755	COG2188	Transcriptional regulator
B9S25_RS01765	COG3457	Alanine racemase
B9S25_RS01770	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B9S25_RS01775	COG1735	metal-dependent hydrolase with the TIM-barrel fold
B9S25_RS01790	COG0626	cystathionine gamma-synthase activity
B9S25_RS01795	COG2188	Transcriptional regulator
B9S25_RS01805	COG1082	Xylose isomerase domain protein TIM barrel
B9S25_RS01810	COG2222	sugar isomerase
B9S25_RS01815	COG0531	amino acid
B9S25_RS01830	COG2116	formate transmembrane transporter activity
B9S25_RS01835	COG2146	nitrite reductase [NAD(P)H] activity
B9S25_RS01840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B9S25_RS01855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B9S25_RS01865	COG2184	nucleotidyltransferase activity
B9S25_RS01870	COG0512	Glutamine amidotransferase of anthranilate synthase
B9S25_RS01875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9S25_RS01880	COG1289	transmembrane transporter activity
B9S25_RS01885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9S25_RS01890	COG1765	OsmC-like protein
B9S25_RS01895	COG3954	Phosphoribulokinase
B9S25_RS01905	COG0429	hydrolase of the alpha beta-hydrolase fold
B9S25_RS01910	COG0488	(ABC) transporter
B9S25_RS01925	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
B9S25_RS01930	COG1047	Peptidyl-prolyl cis-trans
B9S25_RS01940	COG0545	Peptidyl-prolyl cis-trans isomerase
B9S25_RS01945	COG2964	Protein conserved in bacteria
B9S25_RS02015	COG0089	rRNA binding
B9S25_RS02105	COG0201	protein transport
B9S25_RS02145	COG0789	Transcriptional regulator
B9S25_RS02150	COG3036	rescue of stalled ribosome
B9S25_RS02160	COG0569	domain protein
B9S25_RS02180	COG0758	DNA mediated transformation
B9S25_RS02190	COG0551	DNA topoisomerase type I activity
B9S25_RS02210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B9S25_RS02250	COG1126	abc transporter atp-binding protein
B9S25_RS02255	COG0765	amino acid transport
B9S25_RS02275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S25_RS02285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9S25_RS02290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9S25_RS02295	COG1309	transcriptional regulator
B9S25_RS02305	COG2189	Belongs to the N(4) N(6)-methyltransferase family
B9S25_RS02315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B9S25_RS02325	COG4145	pantothenate transmembrane transporter activity
B9S25_RS02330	COG3924	membrane
B9S25_RS02335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S25_RS02340	COG1349	DNA-binding transcription factor activity
B9S25_RS02350	COG1879	ABC-type sugar transport system periplasmic component
B9S25_RS02355	COG1129	ABC transporter
B9S25_RS02360	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S25_RS02365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S25_RS02375	COG0439	Biotin carboxylase
B9S25_RS02380	COG0511	ligase activity, forming carbon-carbon bonds
B9S25_RS02390	COG0604	alcohol dehydrogenase
B9S25_RS02395	COG2200	EAL domain
B9S25_RS02395	COG2199	diguanylate cyclase activity
B9S25_RS02400	COG1077	Cell shape determining protein MreB Mrl
B9S25_RS02405	COG1792	Involved in formation and maintenance of cell shape
B9S25_RS02410	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B9S25_RS02420	COG1530	ribonuclease E activity
B9S25_RS02425	COG3164	Protein of unknown function
B9S25_RS02430	COG0312	modulator of DNA gyrase
B9S25_RS02435	COG0583	DNA-binding transcription factor activity
B9S25_RS02455	COG2732	(Barnase) inhibitor
B9S25_RS02475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9S25_RS02480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9S25_RS02485	COG3105	Protein conserved in bacteria
B9S25_RS02490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B9S25_RS02510	COG0625	glutathione transferase activity
B9S25_RS02515	COG2969	positive regulation of protein catabolic process
B9S25_RS02520	COG3069	C4-dicarboxylate transmembrane transporter activity
B9S25_RS02550	COG2731	YhcH YjgK YiaL family protein
B9S25_RS02560	COG0493	'glutamate synthase
B9S25_RS02565	COG0067	glutamate synthase
B9S25_RS02565	COG0070	glutamate synthase
B9S25_RS02565	COG0069	glutamate synthase activity
B9S25_RS02570	COG1242	4 iron, 4 sulfur cluster binding
B9S25_RS02575	COG5002	protein histidine kinase activity
B9S25_RS02575	COG2198	Histidine kinase
B9S25_RS02575	COG0784	Response regulator, receiver
B9S25_RS02580	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
B9S25_RS02590	COG0515	serine threonine protein kinase
B9S25_RS02595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS02610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B9S25_RS02615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B9S25_RS02620	COG1137	ATPase activity
B9S25_RS02625	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B9S25_RS02630	COG3117	lipopolysaccharide transmembrane transporter activity
B9S25_RS02635	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B9S25_RS02640	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B9S25_RS02640	COG0517	IMP dehydrogenase activity
B9S25_RS02645	COG0530	calcium, potassium:sodium antiporter activity
B9S25_RS02650	COG1127	ABC transporter
B9S25_RS02655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B9S25_RS02660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B9S25_RS02665	COG2854	intermembrane phospholipid transfer
B9S25_RS02670	COG3113	response to antibiotic
B9S25_RS02675	COG5007	Belongs to the BolA IbaG family
B9S25_RS02685	COG3423	Transcriptional regulator
B9S25_RS02690	COG0142	geranyltranstransferase activity
B9S25_RS02705	COG0697	spore germination
B9S25_RS02715	COG2027	D-alanyl-D-alanine carboxypeptidase
B9S25_RS02720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9S25_RS02725	COG1534	Rna-binding protein
B9S25_RS02735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B9S25_RS02740	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B9S25_RS02750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B9S25_RS02760	COG2194	sulfuric ester hydrolase activity
B9S25_RS02780	COG0195	Participates in both transcription termination and antitermination
B9S25_RS02820	COG0513	Belongs to the DEAD box helicase family
B9S25_RS02825	COG0814	amino acid
B9S25_RS02835	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS02840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9S25_RS02845	COG0826	peptidase U32
B9S25_RS02850	COG0826	peptidase U32
B9S25_RS02855	COG3154	lipid carrier protein
B9S25_RS02860	COG3153	acetyltransferase
B9S25_RS02875	COG0693	protein deglycase activity
B9S25_RS02880	COG0702	epimerase
B9S25_RS02885	COG0701	Predicted permease
B9S25_RS02890	COG2823	Periplasmic or secreted lipoprotein
B9S25_RS02910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B9S25_RS02915	COG3539	Fimbrial protein
B9S25_RS02920	COG3188	usher protein
B9S25_RS02925	COG3121	Chaperone
B9S25_RS02930	COG3539	Fimbrial protein
B9S25_RS02935	COG0363	glucosamine-6-phosphate deaminase activity
B9S25_RS02940	COG3716	PTS system mannose fructose sorbose family IID component
B9S25_RS02945	COG3715	PTS system
B9S25_RS02950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS02960	COG2222	sugar isomerase
B9S25_RS02965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B9S25_RS02970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS02975	COG3716	PTS system mannose fructose sorbose family IID component
B9S25_RS02985	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS02995	COG1349	DNA-binding transcription factor activity
B9S25_RS03005	COG2002	toxin-antitoxin pair type II binding
B9S25_RS03010	COG2721	sulfolactate sulfo-lyase activity
B9S25_RS03015	COG2271	Major facilitator Superfamily
B9S25_RS03025	COG2084	Dehydrogenase
B9S25_RS03030	COG1929	Belongs to the glycerate kinase type-1 family
B9S25_RS03055	COG0583	DNA-binding transcription factor activity
B9S25_RS03060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B9S25_RS03070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B9S25_RS03075	COG1882	Formate acetyltransferase
B9S25_RS03080	COG0251	oxidation-reduction process
B9S25_RS03085	COG1760	l-serine dehydratase
B9S25_RS03090	COG0814	amino acid
B9S25_RS03105	COG1741	Belongs to the pirin family
B9S25_RS03110	COG0583	DNA-binding transcription factor activity
B9S25_RS03115	COG3152	Membrane
B9S25_RS03120	COG3152	Membrane
B9S25_RS03125	COG0435	Glutathione S-transferase
B9S25_RS03130	COG2259	Doxx family
B9S25_RS03140	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
B9S25_RS03145	COG4575	ribosome binding
B9S25_RS03150	COG1422	Protein of unknown function (DUF1090)
B9S25_RS03160	COG0586	Pfam SNARE associated Golgi protein
B9S25_RS03165	COG2186	Transcriptional regulator
B9S25_RS03190	COG2271	Major facilitator Superfamily
B9S25_RS03200	COG2721	sulfolactate sulfo-lyase activity
B9S25_RS03210	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
B9S25_RS03215	COG0861	Integral membrane protein TerC family
B9S25_RS03220	COG0673	inositol 2-dehydrogenase activity
B9S25_RS03230	COG1451	nucleotide metabolic process
B9S25_RS03245	COG5499	transcription regulator containing HTH domain
B9S25_RS03250	COG0446	pyridine nucleotide-disulphide oxidoreductase
B9S25_RS03250	COG1902	pentaerythritol trinitrate reductase activity
B9S25_RS03265	COG0531	amino acid
B9S25_RS03270	COG2731	YhcH YjgK YiaL family protein
B9S25_RS03275	COG3250	beta-galactosidase activity
B9S25_RS03280	COG1609	Transcriptional regulator
B9S25_RS03285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9S25_RS03295	COG0840	transmembrane signaling receptor activity
B9S25_RS03300	COG1695	Transcriptional regulator
B9S25_RS03310	COG2375	cellular response to nickel ion
B9S25_RS03325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9S25_RS03330	COG0358	DNA primase activity
B9S25_RS03335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B9S25_RS03345	COG0471	metal ion transport
B9S25_RS03350	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B9S25_RS03355	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B9S25_RS03360	COG0583	DNA-binding transcription factor activity
B9S25_RS03370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B9S25_RS03385	COG4991	sh3 domain protein
B9S25_RS03390	COG3025	triphosphatase activity
B9S25_RS03420	COG1585	Membrane protein implicated in regulation of membrane protease activity
B9S25_RS03435	COG3121	Chaperone
B9S25_RS03440	COG3188	usher protein
B9S25_RS03445	COG3539	Fimbrial protein
B9S25_RS03450	COG2960	long-chain fatty acid transporting porin activity
B9S25_RS03465	COG3384	dioxygenase
B9S25_RS03470	COG0754	glutathionylspermidine amidase activity
B9S25_RS03480	COG1538	Outer membrane efflux protein
B9S25_RS03485	COG0494	nUDIX hydrolase
B9S25_RS03490	COG3151	Protein conserved in bacteria
B9S25_RS03495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B9S25_RS03500	COG3150	esterase
B9S25_RS03505	COG0187	DNA topoisomerase II activity
B9S25_RS03510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B9S25_RS03515	COG2249	NAD(P)H dehydrogenase (quinone) activity
B9S25_RS03525	COG0642	Histidine kinase
B9S25_RS03530	COG0745	RESPONSE REGULATOR receiver
B9S25_RS03535	COG3111	PFAM Bacterial OB fold (BOF) protein
B9S25_RS03540	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B9S25_RS03545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B9S25_RS03550	COG0204	Acyl-transferase
B9S25_RS03555	COG2132	Multicopper oxidase
B9S25_RS03560	COG1032	radical SAM domain protein
B9S25_RS03565	COG4238	major outer membrane lipoprotein
B9S25_RS03575	COG0656	L-ascorbic acid biosynthetic process
B9S25_RS03580	COG1979	alcohol dehydrogenase
B9S25_RS03585	COG2207	Transcriptional regulator
B9S25_RS03590	COG0586	Pfam SNARE associated Golgi protein
B9S25_RS03595	COG0626	cystathionine gamma-synthase activity
B9S25_RS03600	COG0811	peptide transport
B9S25_RS03605	COG0848	biopolymer transport protein
B9S25_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS03620	COG0667	Aldo Keto reductase
B9S25_RS03635	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
B9S25_RS03640	COG0437	4 iron, 4 sulfur cluster binding
B9S25_RS03645	COG5557	Pfam Polysulphide reductase, NrfD
B9S25_RS03650	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B9S25_RS03655	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B9S25_RS03660	COG1773	rubredoxin
B9S25_RS03670	COG0298	carbon dioxide binding
B9S25_RS03675	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS03685	COG0625	glutathione transferase activity
B9S25_RS03690	COG0754	glutathionylspermidine amidase activity
B9S25_RS03695	COG0306	phosphate transporter
B9S25_RS03700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B9S25_RS03705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B9S25_RS03710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B9S25_RS03715	COG2244	polysaccharide biosynthetic process
B9S25_RS03725	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
B9S25_RS03730	COG0795	lipopolysaccharide-transporting ATPase activity
B9S25_RS03740	COG0156	8-amino-7-oxononanoate synthase activity
B9S25_RS03745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9S25_RS03755	COG0318	PFAM AMP-dependent synthetase and ligase
B9S25_RS03760	COG0456	acetyltransferase
B9S25_RS03765	COG2186	Transcriptional regulator
B9S25_RS03770	COG0277	FAD linked oxidase domain protein
B9S25_RS03775	COG0277	FAD linked oxidase domain protein
B9S25_RS03780	COG0247	lactate metabolic process
B9S25_RS03785	COG3193	protein, possibly involved in utilization of glycolate and propanediol
B9S25_RS03790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B9S25_RS03800	COG2194	sulfuric ester hydrolase activity
B9S25_RS03820	COG4771	TonB-dependent receptor
B9S25_RS03840	COG0582	viral genome integration into host DNA
B9S25_RS03850	COG1811	Na channel or pump
B9S25_RS03855	COG1982	Orn Lys Arg decarboxylase major
B9S25_RS03860	COG2211	Major facilitator Superfamily
B9S25_RS03875	COG1194	a g-specific adenine glycosylase
B9S25_RS03885	COG3171	Protein conserved in bacteria
B9S25_RS03895	COG0252	asparaginase activity
B9S25_RS03910	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B9S25_RS03915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B9S25_RS03920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B9S25_RS03935	COG0762	integral membrane protein
B9S25_RS03940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B9S25_RS03945	COG2805	Type II/IV secretion system protein
B9S25_RS03960	COG0189	ligase activity
B9S25_RS03965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B9S25_RS03970	COG2356	endonuclease I
B9S25_RS03980	COG2814	Major facilitator Superfamily
B9S25_RS03995	COG1166	arginine decarboxylase activity
B9S25_RS04020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS04020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS04025	COG3715	PTS system
B9S25_RS04030	COG3716	PTS system mannose fructose sorbose family IID component
B9S25_RS04045	COG0501	Belongs to the peptidase M48B family
B9S25_RS04050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B9S25_RS04055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS04060	COG2213	PTS system mannitol-specific
B9S25_RS04065	COG1063	alcohol dehydrogenase
B9S25_RS04070	COG1494	fructose-1,6-bisphosphatase
B9S25_RS04080	COG1072	(Pantothenic acid kinase))
B9S25_RS04085	COG1122	ATPase activity
B9S25_RS04090	COG1122	ATPase activity
B9S25_RS04120	COG0191	fructose-bisphosphate aldolase activity
B9S25_RS04125	COG0668	transmembrane transport
B9S25_RS04135	COG2968	Membrane
B9S25_RS04140	COG0583	DNA-binding transcription factor activity
B9S25_RS04145	COG0427	acetyl-CoA hydrolase
B9S25_RS04150	COG1024	Enoyl-CoA hydratase
B9S25_RS04155	COG1703	isobutyryl-CoA mutase activity
B9S25_RS04160	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9S25_RS04160	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9S25_RS04180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B9S25_RS04195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B9S25_RS04215	COG0006	proline dipeptidase activity
B9S25_RS04220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9S25_RS04225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9S25_RS04250	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS04255	COG2723	6-phospho-beta-galactosidase activity
B9S25_RS04265	COG1272	protein, Hemolysin III
B9S25_RS04275	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B9S25_RS04285	COG0716	FMN binding
B9S25_RS04290	COG4974	Belongs to the 'phage' integrase family
B9S25_RS04295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B9S25_RS04300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B9S25_RS04330	COG2233	PERMEase
B9S25_RS04335	COG0493	'glutamate synthase
B9S25_RS04335	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS04340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS04345	COG2252	PERMEase
B9S25_RS04350	COG0402	S-adenosylhomocysteine deaminase activity
B9S25_RS04355	COG2233	PERMEase
B9S25_RS04360	COG2080	2 iron, 2 sulfur cluster binding
B9S25_RS04360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B9S25_RS04365	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B9S25_RS04370	COG0402	S-adenosylhomocysteine deaminase activity
B9S25_RS04375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS04375	COG0493	'glutamate synthase
B9S25_RS04380	COG2068	MobA-Related Protein
B9S25_RS04385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B9S25_RS04390	COG3608	succinylglutamate desuccinylase aspartoacylase
B9S25_RS04390	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B9S25_RS04395	COG0549	Belongs to the carbamate kinase family
B9S25_RS04405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9S25_RS04410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B9S25_RS04415	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B9S25_RS04420	COG3829	transcription factor binding
B9S25_RS04425	COG2080	2 iron, 2 sulfur cluster binding
B9S25_RS04430	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B9S25_RS04435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B9S25_RS04440	COG4942	peptidase
B9S25_RS04535	COG4974	Belongs to the 'phage' integrase family
B9S25_RS04570	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS04575	COG4372	Transposase
B9S25_RS04590	COG3387	PFAM Glycoside hydrolase 15-related
B9S25_RS04695	COG0457	Tetratricopeptide repeat
B9S25_RS04695	COG3710	Transcriptional regulator
B9S25_RS04700	COG0457	Tetratricopeptide repeat
B9S25_RS04725	COG3710	Transcriptional regulator
B9S25_RS04730	COG2771	luxR family
B9S25_RS04735	COG0814	amino acid
B9S25_RS04740	COG0183	Belongs to the thiolase family
B9S25_RS04750	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS04755	COG2814	Major facilitator Superfamily
B9S25_RS04760	COG1794	racemase activity, acting on amino acids and derivatives
B9S25_RS04765	COG0583	DNA-binding transcription factor activity
B9S25_RS04775	COG1609	Transcriptional regulator
B9S25_RS04795	COG0667	Aldo Keto reductase
B9S25_RS04805	COG0861	Integral membrane protein TerC family
B9S25_RS04825	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
B9S25_RS04840	COG2165	general secretion pathway protein
B9S25_RS04845	COG4795	General secretion pathway protein
B9S25_RS04855	COG4967	type IV pilus modification protein PilV
B9S25_RS04860	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B9S25_RS04865	COG1025	Belongs to the peptidase M16 family
B9S25_RS04870	COG1074	ATP-dependent DNA helicase activity
B9S25_RS04875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B9S25_RS04880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B9S25_RS04880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B9S25_RS04885	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9S25_RS04890	COG3711	transcriptional antiterminator
B9S25_RS04895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS04895	COG1263	PTS System
B9S25_RS04900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B9S25_RS04930	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B9S25_RS04935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B9S25_RS04940	COG2166	iron-sulfur cluster assembly
B9S25_RS04945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9S25_RS04955	COG0583	DNA-binding transcription factor activity
B9S25_RS04960	COG2363	Small membrane protein
B9S25_RS04970	COG1349	DNA-binding transcription factor activity
B9S25_RS04980	COG1070	Carbohydrate kinase
B9S25_RS04990	COG0738	Major facilitator superfamily
B9S25_RS04995	COG0235	Class ii aldolase
B9S25_RS05000	COG1454	alcohol dehydrogenase
B9S25_RS05010	COG1760	l-serine dehydratase
B9S25_RS05015	COG0814	amino acid
B9S25_RS05020	COG1611	Belongs to the LOG family
B9S25_RS05035	COG3098	single-species biofilm formation
B9S25_RS05040	COG0564	pseudouridine synthase activity
B9S25_RS05045	COG0716	FMN binding
B9S25_RS05050	COG2271	Major facilitator Superfamily
B9S25_RS05055	COG4948	Mandelate Racemase Muconate Lactonizing
B9S25_RS05060	COG4948	Mandelate Racemase Muconate Lactonizing
B9S25_RS05065	COG3437	response regulator, receiver
B9S25_RS05065	COG3850	Histidine kinase
B9S25_RS05065	COG2205	protein histidine kinase activity
B9S25_RS05065	COG4999	Histidine kinase
B9S25_RS05075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9S25_RS05080	COG2336	PFAM SpoVT AbrB
B9S25_RS05085	COG2337	Toxic component of a toxin-antitoxin (TA) module
B9S25_RS05090	COG3956	TIGRFAM MazG family protein
B9S25_RS05105	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B9S25_RS05115	COG0602	queuosine metabolic process
B9S25_RS05120	COG1070	Carbohydrate kinase
B9S25_RS05125	COG2223	nitrite transmembrane transporter activity
B9S25_RS05130	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS05135	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS05140	COG0277	FAD linked oxidase domain protein
B9S25_RS05145	COG0477	Major facilitator Superfamily
B9S25_RS05150	COG2086	electron transfer activity
B9S25_RS05155	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B9S25_RS05160	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B9S25_RS05165	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B9S25_RS05170	COG0644	oxidoreductase
B9S25_RS05175	COG0720	synthase
B9S25_RS05205	COG1203	CRISPR-associated helicase, Cas3
B9S25_RS05220	COG1857	crispr-associated protein
B9S25_RS05235	COG1518	maintenance of DNA repeat elements
B9S25_RS05240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS05245	COG2234	aminopeptidase activity
B9S25_RS05300	COG1388	LysM domain
B9S25_RS05300	COG4942	peptidase
B9S25_RS05305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9S25_RS05320	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B9S25_RS05330	COG2610	gluconate transmembrane transporter activity
B9S25_RS05335	COG3622	Belongs to the hyi family
B9S25_RS05340	COG0235	Class ii aldolase
B9S25_RS05345	COG3395	kinase activity
B9S25_RS05350	COG2084	Dehydrogenase
B9S25_RS05355	COG1349	DNA-binding transcription factor activity
B9S25_RS05360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B9S25_RS05380	COG0309	Hydrogenase expression formation protein (HypE)
B9S25_RS05385	COG0409	Hydrogenase expression formation protein
B9S25_RS05390	COG0298	carbon dioxide binding
B9S25_RS05395	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B9S25_RS05400	COG0375	protein maturation
B9S25_RS05415	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS05420	COG0651	ATP synthesis coupled electron transport
B9S25_RS05425	COG0650	Formate hydrogenlyase subunit 4
B9S25_RS05430	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
B9S25_RS05430	COG3261	NADH dehydrogenase
B9S25_RS05435	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S25_RS05440	COG3260	NADH ubiquinone oxidoreductase 20
B9S25_RS05450	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B9S25_RS05460	COG4680	protein conserved in bacteria
B9S25_RS05465	COG5499	transcription regulator containing HTH domain
B9S25_RS05470	COG2723	6-phospho-beta-galactosidase activity
B9S25_RS05475	COG1263	PTS System
B9S25_RS05475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS05480	COG1609	Transcriptional regulator
B9S25_RS05485	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS05490	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B9S25_RS05515	COG1349	DNA-binding transcription factor activity
B9S25_RS05520	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS05525	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS05535	COG3732	PTS system glucitol sorbitol-specific
B9S25_RS05540	COG3730	PTS system glucitol sorbitol-specific
B9S25_RS05545	COG2951	lytic endotransglycosylase activity
B9S25_RS05550	COG1546	Belongs to the CinA family
B9S25_RS05570	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B9S25_RS05600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9S25_RS05605	COG1238	metal cluster binding
B9S25_RS05620	COG2814	Major facilitator Superfamily
B9S25_RS05625	COG1566	PFAM secretion protein HlyD family protein
B9S25_RS05630	COG1846	Transcriptional regulator
B9S25_RS05640	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B9S25_RS05645	COG2814	Major facilitator Superfamily
B9S25_RS05650	COG2113	Glycine betaine
B9S25_RS05655	COG4176	ABC-type proline glycine betaine transport system permease component
B9S25_RS05660	COG4175	Glycine betaine
B9S25_RS05665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9S25_RS05670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9S25_RS05680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B9S25_RS05685	COG4575	ribosome binding
B9S25_RS05700	COG2916	Histone family protein nucleoid-structuring protein H-NS
B9S25_RS05705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9S25_RS05710	COG0640	Transcriptional regulator
B9S25_RS05715	COG0401	homolog of Blt101
B9S25_RS05720	COG1652	LysM domain
B9S25_RS05725	COG1802	Transcriptional regulator
B9S25_RS05730	COG1113	amino acid transport
B9S25_RS05735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B9S25_RS05740	COG1012	belongs to the aldehyde dehydrogenase family
B9S25_RS05745	COG0579	oxidoreductase
B9S25_RS05780	COG0582	viral genome integration into host DNA
B9S25_RS05790	COG0582	viral genome integration into host DNA
B9S25_RS05835	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
B9S25_RS05840	COG5532	Uncharacterized conserved protein (DUF2303)
B9S25_RS05885	COG1846	Transcriptional regulator
B9S25_RS05895	COG4725	Belongs to the MT-A70-like family
B9S25_RS05905	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B9S25_RS05915	COG1403	HNH endonuclease
B9S25_RS05970	COG3772	lysozyme
B9S25_RS06090	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS06140	COG2867	negative regulation of translational initiation
B9S25_RS06150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9S25_RS06155	COG0497	DNA recombination
B9S25_RS06170	COG4536	flavin adenine dinucleotide binding
B9S25_RS06175	COG4137	Cytochrome C assembly protein
B9S25_RS06180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B9S25_RS06205	COG2885	chlorophyll binding
B9S25_RS06210	COG2199	diguanylate cyclase activity
B9S25_RS06225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B9S25_RS06230	COG0287	Prephenate dehydrogenase
B9S25_RS06230	COG1605	Chorismate mutase
B9S25_RS06235	COG0077	Prephenate dehydratase
B9S25_RS06235	COG1605	Chorismate mutase
B9S25_RS06245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B9S25_RS06250	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9S25_RS06255	COG0564	pseudouridine synthase activity
B9S25_RS06260	COG1496	oxidoreductase activity
B9S25_RS06265	COG0542	response to heat
B9S25_RS06290	COG0477	Major facilitator Superfamily
B9S25_RS06295	COG5544	Lipoprotein
B9S25_RS06300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9S25_RS06305	COG0045	succinate-CoA ligase (ADP-forming) activity
B9S25_RS06305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9S25_RS06305	COG1042	CoA-binding domain protein
B9S25_RS06310	COG3148	PFAM DTW domain containing protein
B9S25_RS06315	COG3118	belongs to the thioredoxin family
B9S25_RS06320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9S25_RS06340	COG0583	DNA-binding transcription factor activity
B9S25_RS06345	COG0513	Belongs to the DEAD box helicase family
B9S25_RS06355	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B9S25_RS06365	COG1595	DNA-templated transcription, initiation
B9S25_RS06370	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
B9S25_RS06375	COG3026	antisigma factor binding
B9S25_RS06380	COG3086	response to oxidative stress
B9S25_RS06390	COG0681	Belongs to the peptidase S26 family
B9S25_RS06410	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B9S25_RS06425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS06430	COG1737	Transcriptional regulator
B9S25_RS06435	COG0560	Phosphoserine phosphatase
B9S25_RS06450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B9S25_RS06450	COG0047	phosphoribosylformylglycinamidine synthase activity
B9S25_RS06455	COG2205	protein histidine kinase activity
B9S25_RS06460	COG3170	Tfp pilus assembly protein FimV
B9S25_RS06465	COG2204	response regulator
B9S25_RS06470	COG0347	Belongs to the P(II) protein family
B9S25_RS06475	COG1017	nitric oxide dioxygenase activity
B9S25_RS06475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B9S25_RS06485	COG1940	carbohydrate kinase activity
B9S25_RS06490	COG0457	Tetratricopeptide repeat
B9S25_RS06495	COG1879	ABC-type sugar transport system periplasmic component
B9S25_RS06500	COG1129	ABC transporter
B9S25_RS06505	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S25_RS06510	COG1063	alcohol dehydrogenase
B9S25_RS06515	COG2017	converts alpha-aldose to the beta-anomer
B9S25_RS06520	COG2259	Doxx family
B9S25_RS06545	COG4638	Rieske (2fe-2S)
B9S25_RS06550	COG0583	DNA-binding transcription factor activity
B9S25_RS06555	COG2814	Major facilitator Superfamily
B9S25_RS06560	COG3711	transcriptional antiterminator
B9S25_RS06565	COG1073	alpha beta
B9S25_RS06570	COG0483	inositol monophosphate 1-phosphatase activity
B9S25_RS06590	COG0822	iron-sulfur transferase activity
B9S25_RS06610	COG0633	Ferredoxin
B9S25_RS06615	COG2975	iron-sulfur cluster assembly
B9S25_RS06630	COG2897	thiosulfate sulfurtransferase activity
B9S25_RS06635	COG2373	Large extracellular alpha-helical protein
B9S25_RS06640	COG4953	penicillin-binding protein 1C
B9S25_RS06670	COG2976	Protein conserved in bacteria
B9S25_RS06685	COG1645	bacterial-type flagellum-dependent swarming motility
B9S25_RS06695	COG0517	IMP dehydrogenase activity
B9S25_RS06695	COG0516	GMP reductase activity
B9S25_RS06710	COG3133	Outer membrane lipoprotein
B9S25_RS06720	COG2200	EAL domain
B9S25_RS06725	COG0248	Ppx GppA phosphatase
B9S25_RS06730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B9S25_RS06735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B9S25_RS06750	COG2233	PERMEase
B9S25_RS06760	COG1393	Belongs to the ArsC family
B9S25_RS06765	COG4783	chaperone-mediated protein folding
B9S25_RS06770	COG0628	permease
B9S25_RS06775	COG2116	formate transmembrane transporter activity
B9S25_RS06780	COG3604	Transcriptional regulator
B9S25_RS06795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S25_RS06800	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
B9S25_RS06800	COG3261	NADH dehydrogenase
B9S25_RS06805	COG0651	ATP synthesis coupled electron transport
B9S25_RS06810	COG4237	Hydrogenase 4 membrane
B9S25_RS06815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B9S25_RS06820	COG0650	Formate hydrogenlyase subunit 4
B9S25_RS06825	COG0651	ATP synthesis coupled electron transport
B9S25_RS06830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS06835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B9S25_RS06840	COG2716	regulation of RNA biosynthetic process
B9S25_RS06850	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B9S25_RS06870	COG2321	neutral zinc metallopeptidase
B9S25_RS06880	COG0400	carboxylic ester hydrolase activity
B9S25_RS06895	COG1393	Belongs to the ArsC family
B9S25_RS06910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9S25_RS06915	COG3850	Histidine kinase
B9S25_RS06920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS06920	COG0493	'glutamate synthase
B9S25_RS06930	COG5342	invasion associated locus B
B9S25_RS06935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B9S25_RS06940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B9S25_RS06945	COG0281	malic enzyme
B9S25_RS06945	COG0280	phosphate acetyltransferase
B9S25_RS06950	COG4810	utilization protein
B9S25_RS06955	COG4917	ethanolamine utilization protein
B9S25_RS06960	COG4766	ethanolamine catabolic process
B9S25_RS06965	COG4812	Cobalamin adenosyltransferase
B9S25_RS06970	COG0280	phosphate acetyltransferase
B9S25_RS06975	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
B9S25_RS06980	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
B9S25_RS06990	COG4820	ethanolamine utilization protein (EutJ)
B9S25_RS06995	COG1454	alcohol dehydrogenase
B9S25_RS07000	COG3192	ethanolamine utilization protein
B9S25_RS07005	COG4819	ethanolamine utilization protein
B9S25_RS07010	COG4303	Ethanolamine ammonia lyase large subunit
B9S25_RS07020	COG4816	utilization protein
B9S25_RS07025	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
B9S25_RS07030	COG2207	Transcriptional regulator
B9S25_RS07040	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9S25_RS07060	COG2837	iron assimilation
B9S25_RS07065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B9S25_RS07070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS07070	COG1263	PTS System
B9S25_RS07085	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS07090	COG4150	thiosulfate binding
B9S25_RS07095	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B9S25_RS07100	COG4208	sulfate ABC transporter
B9S25_RS07105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B9S25_RS07110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B9S25_RS07125	COG2190	(PTS) system
B9S25_RS07130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9S25_RS07135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS07140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B9S25_RS07160	COG3530	Putative quorum-sensing-regulated virulence factor
B9S25_RS07165	COG0385	Bile acid
B9S25_RS07170	COG0583	DNA-binding transcription factor activity
B9S25_RS07180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B9S25_RS07185	COG2211	Major facilitator Superfamily
B9S25_RS07195	COG0583	DNA-binding transcription factor activity
B9S25_RS07230	COG3415	Transposase
B9S25_RS07235	COG3415	Transposase
B9S25_RS07250	COG2199	diguanylate cyclase activity
B9S25_RS07250	COG2200	EAL domain
B9S25_RS07255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B9S25_RS07280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS07285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS07290	COG0006	proline dipeptidase activity
B9S25_RS07295	COG1363	Peptidase, m42
B9S25_RS07305	COG2207	Transcriptional regulator
B9S25_RS07310	COG3279	Response regulator of the LytR AlgR family
B9S25_RS07315	COG3275	phosphorelay sensor kinase activity
B9S25_RS07320	COG0436	Aminotransferase
B9S25_RS07330	COG1560	Kdo2-lipid A biosynthetic process
B9S25_RS07355	COG0028	Belongs to the TPP enzyme family
B9S25_RS07360	COG0679	Auxin Efflux Carrier
B9S25_RS07365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B9S25_RS07370	COG2198	Histidine kinase
B9S25_RS07370	COG0784	Response regulator, receiver
B9S25_RS07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S25_RS07370	COG2205	protein histidine kinase activity
B9S25_RS07375	COG2197	response regulator
B9S25_RS07380	COG1566	PFAM secretion protein HlyD family protein
B9S25_RS07385	COG0477	Major facilitator Superfamily
B9S25_RS07430	COG2003	Belongs to the UPF0758 family
B9S25_RS07450	COG3468	outer membrane autotransporter barrel domain protein
B9S25_RS07510	COG4372	Transposase
B9S25_RS07515	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS07690	COG0305	Participates in initiation and elongation during chromosome replication
B9S25_RS07765	COG3646	Phage regulatory protein
B9S25_RS07785	COG1783	phage Terminase large subunit
B9S25_RS07860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B9S25_RS07865	COG0582	viral genome integration into host DNA
B9S25_RS07875	COG2116	formate transmembrane transporter activity
B9S25_RS07880	COG2853	Lipoprotein
B9S25_RS07890	COG2067	long-chain fatty acid transport protein
B9S25_RS07895	COG3691	Protein conserved in bacteria
B9S25_RS07910	COG2062	phosphohistidine phosphatase, SixA
B9S25_RS07915	COG3539	Fimbrial protein
B9S25_RS07920	COG3188	usher protein
B9S25_RS07925	COG3121	Chaperone
B9S25_RS07930	COG3539	Fimbrial protein
B9S25_RS07935	COG3539	Fimbrial protein
B9S25_RS07940	COG3539	Fimbrial protein
B9S25_RS07970	COG0730	response to heat
B9S25_RS07975	COG3101	peptidyl-lysine hydroxylation
B9S25_RS07990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9S25_RS07995	COG2814	Major facilitator Superfamily
B9S25_RS08010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B9S25_RS08020	COG0586	Pfam SNARE associated Golgi protein
B9S25_RS08030	COG0285	dihydrofolate synthase activity
B9S25_RS08035	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
B9S25_RS08040	COG1286	toxin biosynthetic process
B9S25_RS08045	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B9S25_RS08050	COG0163	prenyltransferase activity
B9S25_RS08055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S25_RS08060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S25_RS08065	COG4215	(ABC) transporter
B9S25_RS08070	COG4160	amino acid transport
B9S25_RS08075	COG4598	ABC transporter
B9S25_RS08080	COG5464	transposase or invertase
B9S25_RS08085	COG1090	epimerase
B9S25_RS08090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B9S25_RS08095	COG0625	glutathione transferase activity
B9S25_RS08100	COG0625	glutathione transferase activity
B9S25_RS08105	COG0622	Phosphoesterase
B9S25_RS08110	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B9S25_RS08115	COG1288	antiporter activity
B9S25_RS08120	COG0280	phosphate acetyltransferase
B9S25_RS08120	COG0857	belongs to the CobB CobQ family
B9S25_RS08125	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B9S25_RS08140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9S25_RS08145	COG0471	metal ion transport
B9S25_RS08145	COG0490	domain, Protein
B9S25_RS08155	COG0436	Aminotransferase
B9S25_RS08160	COG0583	DNA-binding transcription factor activity
B9S25_RS08180	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B9S25_RS08185	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B9S25_RS08190	COG1034	ATP synthesis coupled electron transport
B9S25_RS08205	COG0839	Belongs to the complex I subunit 6 family
B9S25_RS08215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B9S25_RS08220	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S25_RS08235	COG2234	aminopeptidase activity
B9S25_RS08240	COG2304	oxidoreductase activity
B9S25_RS08255	COG2153	protein acetylation
B9S25_RS08260	COG4575	ribosome binding
B9S25_RS08265	COG1169	isochorismate synthase
B9S25_RS08280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B9S25_RS08290	COG0318	PFAM AMP-dependent synthetase and ligase
B9S25_RS08360	COG5464	transposase or invertase
B9S25_RS08365	COG0247	lactate metabolic process
B9S25_RS08375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B9S25_RS08380	COG2271	Major facilitator Superfamily
B9S25_RS08385	COG0584	glycerophosphoryl diester phosphodiesterase
B9S25_RS08395	COG3642	lipopolysaccharide core region biosynthetic process
B9S25_RS08400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B9S25_RS08405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9S25_RS08410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9S25_RS08415	COG3468	outer membrane autotransporter barrel domain protein
B9S25_RS08425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B9S25_RS08430	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
B9S25_RS08435	COG3234	Protein of unknown function (DUF1175)
B9S25_RS08440	COG0582	viral genome integration into host DNA
B9S25_RS08650	COG3772	lysozyme
B9S25_RS08670	COG4220	transposase activity
B9S25_RS08775	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS08780	COG4372	Transposase
B9S25_RS08795	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS08830	COG2373	Large extracellular alpha-helical protein
B9S25_RS08835	COG5445	Predicted secreted protein (DUF2300)
B9S25_RS08840	COG4676	Protein conserved in bacteria
B9S25_RS08845	COG0784	Response regulator, receiver
B9S25_RS08845	COG2205	protein histidine kinase activity
B9S25_RS08850	COG2197	response regulator
B9S25_RS08855	COG0642	Histidine kinase
B9S25_RS08855	COG2198	Histidine kinase
B9S25_RS08860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B9S25_RS08865	COG1477	protein flavinylation
B9S25_RS08870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B9S25_RS08870	COG2169	Transcriptional regulator
B9S25_RS08875	COG3145	DNA-N1-methyladenine dioxygenase activity
B9S25_RS08880	COG4615	Cyclic peptide transporter
B9S25_RS08895	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS08895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9S25_RS08900	COG3062	negative regulation of establishment of protein localization
B9S25_RS08910	COG0437	4 iron, 4 sulfur cluster binding
B9S25_RS08915	COG0348	domain, Protein
B9S25_RS08920	COG3043	anaerobic respiration
B9S25_RS08925	COG3005	denitrification pathway
B9S25_RS08930	COG4133	protoheme IX ABC transporter activity
B9S25_RS08935	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9S25_RS08940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9S25_RS08945	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9S25_RS08955	COG1138	Cytochrome C-type biogenesis protein
B9S25_RS08960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9S25_RS08965	COG3088	subunit of a heme lyase
B9S25_RS08965	COG4235	cytochrome complex assembly
B9S25_RS08970	COG2197	response regulator
B9S25_RS09055	COG0582	viral genome integration into host DNA
B9S25_RS09065	COG3083	sulfuric ester hydrolase activity
B9S25_RS09085	COG1061	Type III restriction enzyme res subunit
B9S25_RS09090	COG1187	pseudouridine synthase activity
B9S25_RS09095	COG2814	Major facilitator Superfamily
B9S25_RS09105	COG4172	Belongs to the ABC transporter superfamily
B9S25_RS09110	COG4239	(ABC) transporter, permease
B9S25_RS09115	COG4174	ABC transporter (Permease)
B9S25_RS09120	COG4166	transmembrane transport
B9S25_RS09125	COG2200	EAL domain
B9S25_RS09130	COG0791	NLP P60 protein
B9S25_RS09135	COG0671	phosphoesterase, PA-phosphatase related
B9S25_RS09140	COG0523	cobalamin synthesis protein
B9S25_RS09145	COG0246	Mannitol dehydrogenase
B9S25_RS09160	COG2814	Major facilitator Superfamily
B9S25_RS09165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS09165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS09170	COG1105	Belongs to the carbohydrate kinase PfkB family
B9S25_RS09175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B9S25_RS09175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS09175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS09180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S25_RS09185	COG2313	pseudouridylate synthase activity
B9S25_RS09190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B9S25_RS09195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9S25_RS09205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B9S25_RS09210	COG1522	sequence-specific DNA binding
B9S25_RS09210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S25_RS09220	COG2855	membrane
B9S25_RS09225	COG0583	DNA-binding transcription factor activity
B9S25_RS09230	COG0833	amino acid
B9S25_RS09235	COG4771	TonB-dependent receptor
B9S25_RS09250	COG2311	Membrane
B9S25_RS09255	COG1609	Transcriptional regulator
B9S25_RS09260	COG1879	ABC-type sugar transport system periplasmic component
B9S25_RS09265	COG1129	ABC transporter
B9S25_RS09270	COG4211	Belongs to the binding-protein-dependent transport system permease family
B9S25_RS09275	COG0167	dihydroorotate dehydrogenase activity
B9S25_RS09275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B9S25_RS09280	COG0493	'glutamate synthase
B9S25_RS09290	COG2949	membrane
B9S25_RS09300	COG1346	cytolysis
B9S25_RS09310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B9S25_RS09325	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS09330	COG0586	Pfam SNARE associated Golgi protein
B9S25_RS09340	COG1686	Belongs to the peptidase S11 family
B9S25_RS09345	COG0277	FAD linked oxidase domain protein
B9S25_RS09350	COG1472	Belongs to the glycosyl hydrolase 3 family
B9S25_RS09355	COG1732	Glycine betaine
B9S25_RS09360	COG1174	glycine betaine transport
B9S25_RS09365	COG1125	glycine betaine transport
B9S25_RS09370	COG1174	glycine betaine transport
B9S25_RS09380	COG0789	Transcriptional regulator
B9S25_RS09385	COG0582	viral genome integration into host DNA
B9S25_RS09420	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
B9S25_RS09425	COG5532	Uncharacterized conserved protein (DUF2303)
B9S25_RS09445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B9S25_RS09450	COG4197	protein conserved in bacteria, prophage-related
B9S25_RS09465	COG1846	Transcriptional regulator
B9S25_RS09480	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B9S25_RS09490	COG1403	HNH endonuclease
B9S25_RS09495	COG0484	heat shock protein binding
B9S25_RS09535	COG3772	lysozyme
B9S25_RS09660	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS09665	COG4372	Transposase
B9S25_RS09670	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS09695	COG3275	phosphorelay sensor kinase activity
B9S25_RS09700	COG3279	Response regulator of the LytR AlgR family
B9S25_RS09705	COG4807	Protein conserved in bacteria
B9S25_RS09715	COG4372	Transposase
B9S25_RS09720	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS09730	COG4715	Zinc finger, swim domain protein
B9S25_RS09735	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B9S25_RS09740	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B9S25_RS09745	COG0714	Associated with various cellular activities
B9S25_RS09755	COG3831	ATPase activity
B9S25_RS09770	COG0489	protein tyrosine kinase activity
B9S25_RS09780	COG3539	Fimbrial protein
B9S25_RS09785	COG3121	Chaperone
B9S25_RS09790	COG3188	usher protein
B9S25_RS09795	COG3539	Fimbrial protein
B9S25_RS09800	COG5455	response to cobalt ion
B9S25_RS09805	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
B9S25_RS09820	COG0351	phosphomethylpyrimidine kinase
B9S25_RS09825	COG3757	hydrolase, family 25
B9S25_RS09830	COG2188	Transcriptional regulator
B9S25_RS09835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S25_RS09840	COG1397	ADP-ribosylglycohydrolase
B9S25_RS09845	COG2211	Major facilitator Superfamily
B9S25_RS09850	COG1830	Aldolase
B9S25_RS09870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS09875	COG3414	Phosphotransferase system galactitol-specific IIB component
B9S25_RS09880	COG3775	system Galactitol-specific IIC component
B9S25_RS09905	COG0826	peptidase U32
B9S25_RS09915	COG3609	addiction module antidote protein, CC2985 family
B9S25_RS09925	COG0745	RESPONSE REGULATOR receiver
B9S25_RS09930	COG2205	protein histidine kinase activity
B9S25_RS09970	COG4245	von Willebrand factor, type A
B9S25_RS09975	COG0631	protein serine/threonine phosphatase activity
B9S25_RS09980	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
B9S25_RS09985	COG0443	Heat shock 70 kDa protein
B9S25_RS09990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B9S25_RS10000	COG0572	uridine kinase
B9S25_RS10010	COG2982	Protein involved in outer membrane biogenesis
B9S25_RS10015	COG1253	flavin adenine dinucleotide binding
B9S25_RS10020	COG1596	polysaccharide export
B9S25_RS10025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B9S25_RS10030	COG0489	protein tyrosine kinase activity
B9S25_RS10030	COG3206	protein involved in exopolysaccharide biosynthesis
B9S25_RS10035	COG0463	Glycosyl transferase, family 2
B9S25_RS10040	COG1045	serine acetyltransferase
B9S25_RS10045	COG0438	transferase activity, transferring glycosyl groups
B9S25_RS10055	COG1216	Glycosyl transferase, family 2
B9S25_RS10060	COG0110	maltose O-acetyltransferase activity
B9S25_RS10065	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B9S25_RS10070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9S25_RS10075	COG1051	belongs to the nudix hydrolase family
B9S25_RS10080	COG0297	glycogen (starch) synthase activity
B9S25_RS10085	COG0662	Cupin 2, conserved barrel domain protein
B9S25_RS10085	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
B9S25_RS10090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9S25_RS10095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B9S25_RS10100	COG2244	polysaccharide biosynthetic process
B9S25_RS10105	COG2327	Polysaccharide pyruvyl transferase
B9S25_RS10110	COG0438	transferase activity, transferring glycosyl groups
B9S25_RS10120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B9S25_RS10125	COG1088	dTDP-glucose 4,6-dehydratase activity
B9S25_RS10130	COG1091	dTDP-4-dehydrorhamnose reductase activity
B9S25_RS10170	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B9S25_RS10185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B9S25_RS10190	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B9S25_RS10220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B9S25_RS10225	COG0131	Imidazoleglycerol-phosphate dehydratase
B9S25_RS10225	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B9S25_RS10235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B9S25_RS10250	COG2161	toxin-antitoxin pair type II binding
B9S25_RS10255	COG4115	mRNA cleavage
B9S25_RS10260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9S25_RS10265	COG0583	DNA-binding transcription factor activity
B9S25_RS10275	COG0531	amino acid
B9S25_RS10280	COG2391	methyltransferase activity
B9S25_RS10285	COG0425	Belongs to the sulfur carrier protein TusA family
B9S25_RS10290	COG2925	Exonuclease
B9S25_RS10295	COG1686	Belongs to the peptidase S11 family
B9S25_RS10305	COG1289	transmembrane transporter activity
B9S25_RS10315	COG4917	ethanolamine utilization protein
B9S25_RS10355	COG2003	Belongs to the UPF0758 family
B9S25_RS10390	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS10395	COG4372	Transposase
B9S25_RS10405	COG2020	methyltransferase activity
B9S25_RS10410	COG3468	outer membrane autotransporter barrel domain protein
B9S25_RS10430	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS10435	COG4372	Transposase
B9S25_RS10500	COG1735	metal-dependent hydrolase with the TIM-barrel fold
B9S25_RS10520	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
B9S25_RS10535	COG1376	ErfK ybiS ycfS ynhG family protein
B9S25_RS10545	COG0583	DNA-binding transcription factor activity
B9S25_RS10560	COG0534	Mate efflux family protein
B9S25_RS10570	COG0217	transcriptional regulatory protein
B9S25_RS10575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B9S25_RS10580	COG0477	Major facilitator Superfamily
B9S25_RS10595	COG1388	LysM domain
B9S25_RS10595	COG1470	cell adhesion involved in biofilm formation
B9S25_RS10600	COG4932	domain protein
B9S25_RS10600	COG2373	Large extracellular alpha-helical protein
B9S25_RS10600	COG1388	LysM domain
B9S25_RS10605	COG4771	TonB-dependent receptor
B9S25_RS10610	COG1021	2,3-dihydroxybenzoate-AMP ligase
B9S25_RS10630	COG2226	methyltransferase
B9S25_RS10630	COG3433	isochorismatase activity
B9S25_RS10630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S25_RS10645	COG1132	(ABC) transporter
B9S25_RS10650	COG2814	Major facilitator Superfamily
B9S25_RS10655	COG1169	isochorismate synthase
B9S25_RS10680	COG3443	Belongs to the bacterial solute-binding protein 9 family
B9S25_RS10695	COG2351	hydroxyisourate hydrolase activity
B9S25_RS10700	COG0745	RESPONSE REGULATOR receiver
B9S25_RS10705	COG2205	protein histidine kinase activity
B9S25_RS10725	COG0270	DNA (cytosine-5-)-methyltransferase activity
B9S25_RS10730	COG3727	T/G mismatch-specific endonuclease activity
B9S25_RS10735	COG0697	spore germination
B9S25_RS10740	COG2354	Protein conserved in bacteria
B9S25_RS10745	COG5475	Uncharacterized small protein (DUF2158)
B9S25_RS10780	COG2197	response regulator
B9S25_RS10785	COG1684	flagellar biosynthetic protein fliR
B9S25_RS10790	COG1987	bacterial-type flagellum assembly
B9S25_RS10795	COG1338	Plays a role in the flagellum-specific transport system
B9S25_RS10800	COG3190	flagellar
B9S25_RS10805	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B9S25_RS10810	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B9S25_RS10815	COG1580	Controls the rotational direction of flagella during chemotaxis
B9S25_RS10820	COG3144	bacterial-type flagellum assembly
B9S25_RS10825	COG2882	bacterial-type flagellum organization
B9S25_RS10830	COG1157	protein secretion by the type III secretion system
B9S25_RS10835	COG1317	bacterial-type flagellum organization
B9S25_RS10840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B9S25_RS10845	COG1766	The M ring may be actively involved in energy transduction
B9S25_RS10860	COG2135	peptidase activity
B9S25_RS10865	COG0425	Belongs to the sulfur carrier protein TusA family
B9S25_RS10870	COG2391	methyltransferase activity
B9S25_RS10880	COG0366	Alpha amylase catalytic
B9S25_RS10890	COG1516	flagellar protein fliS
B9S25_RS10905	COG1191	sigma factor activity
B9S25_RS10915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S25_RS10925	COG0765	amino acid transport
B9S25_RS10930	COG1126	abc transporter atp-binding protein
B9S25_RS10935	COG2197	response regulator
B9S25_RS10955	COG2197	response regulator
B9S25_RS11055	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B9S25_RS11060	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS11145	COG4695	Portal protein
B9S25_RS11230	COG4974	Belongs to the 'phage' integrase family
B9S25_RS11235	COG3318	Belongs to the UPF0149 family
B9S25_RS11235	COG3012	SEC-C Motif Domain Protein
B9S25_RS11240	COG0814	amino acid
B9S25_RS11250	COG1528	Iron-storage protein
B9S25_RS11270	COG1528	Iron-storage protein
B9S25_RS11275	COG1879	ABC-type sugar transport system periplasmic component
B9S25_RS11280	COG1129	ABC transporter
B9S25_RS11285	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S25_RS11290	COG1877	trehalose-phosphatase activity
B9S25_RS11300	COG0589	response to stress
B9S25_RS11315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B9S25_RS11320	COG1360	Flagellar Motor Protein
B9S25_RS11325	COG2198	Histidine kinase
B9S25_RS11325	COG0643	Histidine kinase
B9S25_RS11330	COG0835	chemotaxis
B9S25_RS11335	COG0840	transmembrane signaling receptor activity
B9S25_RS11340	COG0840	transmembrane signaling receptor activity
B9S25_RS11345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B9S25_RS11350	COG2201	protein-glutamate methylesterase activity
B9S25_RS11355	COG0745	RESPONSE REGULATOR receiver
B9S25_RS11360	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B9S25_RS11365	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B9S25_RS11370	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B9S25_RS11380	COG3755	Protein conserved in bacteria
B9S25_RS11390	COG3102	Protein conserved in bacteria
B9S25_RS11400	COG3005	denitrification pathway
B9S25_RS11405	COG0243	molybdopterin cofactor binding
B9S25_RS11420	COG3788	relative of glutathione S-transferase, MAPEG superfamily
B9S25_RS11425	COG1801	Protein of unknown function DUF72
B9S25_RS11430	COG0582	viral genome integration into host DNA
B9S25_RS11480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B9S25_RS11510	COG1484	DNA-dependent DNA replication
B9S25_RS11515	COG0305	Participates in initiation and elongation during chromosome replication
B9S25_RS11525	COG1403	HNH endonuclease
B9S25_RS11595	COG3772	lysozyme
B9S25_RS11715	COG2032	superoxide dismutase activity
B9S25_RS11730	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS11760	COG1335	isochorismatase
B9S25_RS11770	COG0494	nUDIX hydrolase
B9S25_RS11775	COG0217	transcriptional regulatory protein
B9S25_RS11805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B9S25_RS11815	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
B9S25_RS11820	COG0739	heme binding
B9S25_RS11825	COG1560	Kdo2-lipid A biosynthetic process
B9S25_RS11845	COG3842	ATPase activity
B9S25_RS11855	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9S25_RS11865	COG2182	Extracellular solute-binding protein
B9S25_RS11870	COG1175	transmembrane transport
B9S25_RS11875	COG3833	ABC-type maltose transport systems, permease component
B9S25_RS11900	COG0469	pyruvate kinase activity
B9S25_RS11905	COG1737	Transcriptional regulator
B9S25_RS11910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B9S25_RS11915	COG0129	dihydroxy-acid dehydratase activity
B9S25_RS11920	COG0800	Aldolase
B9S25_RS11930	COG3141	response to X-ray
B9S25_RS11940	COG2979	Protein of unknown function (DUF533)
B9S25_RS11945	COG1770	oligopeptidase
B9S25_RS11950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS11955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9S25_RS11965	COG2372	response to copper ion
B9S25_RS11970	COG1276	copper resistance
B9S25_RS11980	COG0582	viral genome integration into host DNA
B9S25_RS12000	COG3723	Recombinational DNA repair protein, rece pathway
B9S25_RS12005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS12055	COG1846	Transcriptional regulator
B9S25_RS12065	COG1846	Transcriptional regulator
B9S25_RS12100	COG3111	PFAM Bacterial OB fold (BOF) protein
B9S25_RS12110	COG1403	HNH endonuclease
B9S25_RS12115	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B9S25_RS12120	COG0484	heat shock protein binding
B9S25_RS12145	COG3772	lysozyme
B9S25_RS12165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS12220	COG1484	DNA-dependent DNA replication
B9S25_RS12225	COG1846	Transcriptional regulator
B9S25_RS12270	COG1403	HNH endonuclease
B9S25_RS12275	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B9S25_RS12295	COG2207	Transcriptional regulator
B9S25_RS12345	COG3772	lysozyme
B9S25_RS12375	COG4220	transposase activity
B9S25_RS12395	COG1030	water channel activity
B9S25_RS12475	COG2032	superoxide dismutase activity
B9S25_RS12490	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS12520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B9S25_RS12540	COG3008	intermembrane lipid transfer
B9S25_RS12545	COG2995	paraquat-inducible protein a
B9S25_RS12550	COG1956	GAF domain-containing protein
B9S25_RS12560	COG0793	Belongs to the peptidase S41A family
B9S25_RS12570	COG2814	Major facilitator Superfamily
B9S25_RS12575	COG1414	Transcriptional regulator
B9S25_RS12605	COG2226	methyltransferase
B9S25_RS12620	COG3716	PTS system mannose fructose sorbose family IID component
B9S25_RS12625	COG3715	PTS system
B9S25_RS12630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS12630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS12635	COG1253	flavin adenine dinucleotide binding
B9S25_RS12640	COG2200	EAL domain
B9S25_RS12645	COG1760	l-serine dehydratase
B9S25_RS12655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B9S25_RS12670	COG0251	oxidation-reduction process
B9S25_RS12675	COG1199	ATP-dependent helicase activity
B9S25_RS12680	COG1214	PFAM Peptidase M22, glycoprotease
B9S25_RS12685	COG3065	identical protein binding
B9S25_RS12690	COG0318	PFAM AMP-dependent synthetase and ligase
B9S25_RS12695	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B9S25_RS12700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B9S25_RS12705	COG4638	Rieske (2fe-2S)
B9S25_RS12710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B9S25_RS12715	COG0473	3-isopropylmalate dehydrogenase activity
B9S25_RS12720	COG0583	DNA-binding transcription factor activity
B9S25_RS12730	COG3615	Tellurite resistance protein tehB
B9S25_RS12745	COG0675	Transposase, IS605 OrfB family
B9S25_RS12750	COG2261	transglycosylase associated protein
B9S25_RS12765	COG2203	Gaf domain
B9S25_RS12765	COG2199	diguanylate cyclase activity
B9S25_RS12770	COG3042	response to heat
B9S25_RS12775	COG3189	MarR family transcriptional regulator
B9S25_RS12780	COG2807	transmembrane transport
B9S25_RS12785	COG2207	Transcriptional regulator
B9S25_RS12800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B9S25_RS12805	COG2199	diguanylate cyclase activity
B9S25_RS12810	COG2199	diguanylate cyclase activity
B9S25_RS12820	COG2766	serine protein kinase
B9S25_RS12825	COG3713	MltA-interacting MipA family protein
B9S25_RS12830	COG0656	L-ascorbic acid biosynthetic process
B9S25_RS12835	COG0676	glucose-6-phosphate 1-epimerase activity
B9S25_RS12840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B9S25_RS12850	COG3139	Protein of unknown function (DUF1315)
B9S25_RS12855	COG1335	isochorismatase
B9S25_RS12860	COG0252	asparaginase activity
B9S25_RS12865	COG0616	signal peptide processing
B9S25_RS12870	COG0778	Nitroreductase
B9S25_RS12880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B9S25_RS12890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B9S25_RS12900	COG0494	nUDIX hydrolase
B9S25_RS12905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B9S25_RS12910	COG2897	thiosulfate sulfurtransferase activity
B9S25_RS12915	COG4136	ATPase activity
B9S25_RS12920	COG4135	transport system, permease component
B9S25_RS12925	COG4134	Bacterial extracellular solute-binding protein
B9S25_RS12930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B9S25_RS12935	COG0398	Pfam SNARE associated Golgi protein
B9S25_RS12945	COG0398	Pfam SNARE associated Golgi protein
B9S25_RS12950	COG0708	Exodeoxyribonuclease III
B9S25_RS12980	COG3678	ATP-independent chaperone mediated protein folding
B9S25_RS12990	COG0322	excinuclease ABC activity
B9S25_RS13000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9S25_RS13010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B9S25_RS13015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B9S25_RS13020	COG1447	Phosphotransferase system cellobiose-specific component IIA
B9S25_RS13025	COG2169	Transcriptional regulator
B9S25_RS13025	COG1917	Cupin 2, conserved barrel domain protein
B9S25_RS13030	COG1486	melibiose metabolic process
B9S25_RS13045	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS13050	COG0753	catalase activity
B9S25_RS13070	COG1823	symporter activity
B9S25_RS13075	COG1988	membrane-bound metal-dependent
B9S25_RS13080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9S25_RS13090	COG3001	Fructosamine kinase
B9S25_RS13100	COG1105	Belongs to the carbohydrate kinase PfkB family
B9S25_RS13105	COG3137	Salt-induced outer membrane protein
B9S25_RS13165	COG0386	Belongs to the glutathione peroxidase family
B9S25_RS13175	COG0791	NLP P60 protein
B9S25_RS13180	COG2200	EAL domain
B9S25_RS13190	COG4256	Hemin uptake protein
B9S25_RS13195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B9S25_RS13205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9S25_RS13205	COG0574	Belongs to the PEP-utilizing enzyme family
B9S25_RS13210	COG0318	PFAM AMP-dependent synthetase and ligase
B9S25_RS13215	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B9S25_RS13220	COG0644	oxidoreductase
B9S25_RS13225	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B9S25_RS13230	COG2086	electron transfer activity
B9S25_RS13235	COG2207	Transcriptional regulator
B9S25_RS13235	COG1917	Cupin 2, conserved barrel domain protein
B9S25_RS13240	COG1960	acyl-CoA dehydrogenase activity
B9S25_RS13260	COG2271	Major facilitator Superfamily
B9S25_RS13265	COG0738	Major facilitator superfamily
B9S25_RS13280	COG0628	permease
B9S25_RS13285	COG0247	lactate metabolic process
B9S25_RS13285	COG0277	FAD linked oxidase domain protein
B9S25_RS13290	COG2050	protein possibly involved in aromatic compounds catabolism
B9S25_RS13300	COG0316	Belongs to the HesB IscA family
B9S25_RS13305	COG0719	Fe-S assembly protein
B9S25_RS13310	COG0396	ATPase activity
B9S25_RS13315	COG0719	Fe-S assembly protein
B9S25_RS13330	COG1376	ErfK ybiS ycfS ynhG family protein
B9S25_RS13335	COG4238	major outer membrane lipoprotein
B9S25_RS13340	COG0469	pyruvate kinase activity
B9S25_RS13350	COG0437	4 iron, 4 sulfur cluster binding
B9S25_RS13355	COG2414	aldehyde ferredoxin oxidoreductase
B9S25_RS13365	COG0437	4 iron, 4 sulfur cluster binding
B9S25_RS13370	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
B9S25_RS13380	COG4529	Protein conserved in bacteria
B9S25_RS13400	COG3468	outer membrane autotransporter barrel domain protein
B9S25_RS13410	COG0307	riboflavin synthase, alpha
B9S25_RS13415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B9S25_RS13420	COG2814	Major facilitator Superfamily
B9S25_RS13425	COG0583	DNA-binding transcription factor activity
B9S25_RS13440	COG2814	Major facilitator Superfamily
B9S25_RS13445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B9S25_RS13450	COG0791	NLP P60 protein
B9S25_RS13455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B9S25_RS13460	COG1201	RNA secondary structure unwinding
B9S25_RS13470	COG0346	lactoylglutathione lyase activity
B9S25_RS13475	COG1902	pentaerythritol trinitrate reductase activity
B9S25_RS13480	COG1309	transcriptional regulator
B9S25_RS13485	COG3313	Fe-S protein
B9S25_RS13490	COG4989	oxidoreductase activity
B9S25_RS13495	COG2032	superoxide dismutase activity
B9S25_RS13500	COG1289	transmembrane transporter activity
B9S25_RS13505	COG1566	PFAM secretion protein HlyD family protein
B9S25_RS13520	COG3133	Outer membrane lipoprotein
B9S25_RS13530	COG3895	Periplasmic Protein
B9S25_RS13545	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B9S25_RS13550	COG0625	glutathione transferase activity
B9S25_RS13555	COG3104	oligopeptide transport
B9S25_RS13560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B9S25_RS13570	COG4659	FMN binding
B9S25_RS13610	COG0673	inositol 2-dehydrogenase activity
B9S25_RS13620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B9S25_RS13625	COG1263	PTS System
B9S25_RS13625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS13630	COG1609	Transcriptional regulator
B9S25_RS13635	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS13640	COG1309	transcriptional regulator
B9S25_RS13645	COG3250	beta-galactosidase activity
B9S25_RS13660	COG5339	Protein conserved in bacteria
B9S25_RS13665	COG1482	cell wall glycoprotein biosynthetic process
B9S25_RS13670	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B9S25_RS13670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B9S25_RS13675	COG0114	fumarate hydratase activity
B9S25_RS13685	COG2205	protein histidine kinase activity
B9S25_RS13690	COG0745	RESPONSE REGULATOR receiver
B9S25_RS13695	COG3136	membrane protein required for alginate biosynthesis
B9S25_RS13705	COG0531	amino acid
B9S25_RS13715	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B9S25_RS13720	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B9S25_RS13840	COG4626	Terminase
B9S25_RS13840	COG1802	Transcriptional regulator
B9S25_RS13870	COG3591	Belongs to the peptidase S1B family
B9S25_RS13885	COG2814	Major facilitator Superfamily
B9S25_RS13890	COG0583	DNA-binding transcription factor activity
B9S25_RS13895	COG1940	carbohydrate kinase activity
B9S25_RS13900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B9S25_RS13910	COG3381	protein complex oligomerization
B9S25_RS13915	COG3302	dmso reductase anchor subunit
B9S25_RS13920	COG0437	4 iron, 4 sulfur cluster binding
B9S25_RS13925	COG0243	molybdopterin cofactor binding
B9S25_RS13945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9S25_RS13960	COG4948	Mandelate Racemase Muconate Lactonizing
B9S25_RS13965	COG1063	alcohol dehydrogenase
B9S25_RS13975	COG0582	viral genome integration into host DNA
B9S25_RS13990	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS13995	COG4372	Transposase
B9S25_RS14005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS14030	COG1396	sequence-specific DNA binding
B9S25_RS14045	COG1846	Transcriptional regulator
B9S25_RS14055	COG2801	Transposase and inactivated derivatives
B9S25_RS14070	COG3077	Addiction module antitoxin, RelB DinJ family
B9S25_RS14075	COG2026	Addiction module toxin, RelE StbE family
B9S25_RS14095	COG1403	HNH endonuclease
B9S25_RS14110	COG1278	Cold shock
B9S25_RS14115	COG1278	Cold shock
B9S25_RS14130	COG3772	lysozyme
B9S25_RS14140	COG1278	Cold shock
B9S25_RS14165	COG5562	phage envelope protein
B9S25_RS14195	COG0740	serine-type endopeptidase activity
B9S25_RS14270	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS14275	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B9S25_RS14280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B9S25_RS14300	COG0477	Major facilitator Superfamily
B9S25_RS14305	COG0246	Mannitol dehydrogenase
B9S25_RS14315	COG1802	Transcriptional regulator
B9S25_RS14320	COG4221	oxidoreductase activity
B9S25_RS14325	COG0339	signal peptide processing
B9S25_RS14330	COG1546	Belongs to the CinA family
B9S25_RS14335	COG3111	PFAM Bacterial OB fold (BOF) protein
B9S25_RS14360	COG2814	Major facilitator Superfamily
B9S25_RS14365	COG0697	spore germination
B9S25_RS14370	COG2188	Transcriptional regulator
B9S25_RS14380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B9S25_RS14385	COG1447	Phosphotransferase system cellobiose-specific component IIA
B9S25_RS14395	COG2723	6-phospho-beta-galactosidase activity
B9S25_RS14405	COG4977	sequence-specific DNA binding
B9S25_RS14410	COG1846	Transcriptional regulator
B9S25_RS14435	COG0583	DNA-binding transcription factor activity
B9S25_RS14440	COG1012	belongs to the aldehyde dehydrogenase family
B9S25_RS14445	COG2066	Belongs to the glutaminase family
B9S25_RS14455	COG2199	diguanylate cyclase activity
B9S25_RS14465	COG3781	membrane
B9S25_RS14510	COG2911	Protein conserved in bacteria
B9S25_RS14510	COG3210	domain, Protein
B9S25_RS14525	COG1396	sequence-specific DNA binding
B9S25_RS14530	COG3550	peptidyl-serine autophosphorylation
B9S25_RS14540	COG3539	Fimbrial protein
B9S25_RS14550	COG3188	usher protein
B9S25_RS14555	COG3539	Fimbrial protein
B9S25_RS14560	COG3539	Fimbrial protein
B9S25_RS14565	COG3539	Fimbrial protein
B9S25_RS14575	COG0243	molybdopterin cofactor binding
B9S25_RS14585	COG2207	Transcriptional regulator
B9S25_RS14590	COG3119	arylsulfatase activity
B9S25_RS14595	COG0641	radical SAM
B9S25_RS14605	COG4178	(ABC) transporter
B9S25_RS14610	COG4771	TonB-dependent receptor
B9S25_RS14615	COG0612	Peptidase, M16
B9S25_RS14620	COG0076	glutamate decarboxylase activity
B9S25_RS14625	COG0531	amino acid
B9S25_RS14630	COG1649	PFAM Uncharacterised BCR, COG1649
B9S25_RS14640	COG2200	EAL domain
B9S25_RS14640	COG2202	Pas domain
B9S25_RS14640	COG2199	diguanylate cyclase activity
B9S25_RS14645	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B9S25_RS14650	COG0747	negative chemotaxis
B9S25_RS14655	COG0601	transmembrane transport
B9S25_RS14660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S25_RS14665	COG0444	Belongs to the ABC transporter superfamily
B9S25_RS14670	COG4608	Belongs to the ABC transporter superfamily
B9S25_RS14675	COG1764	response to oxidative stress
B9S25_RS14695	COG1064	alcohol dehydrogenase
B9S25_RS14700	COG3093	addiction module antidote protein HigA
B9S25_RS14705	COG2864	formate dehydrogenase
B9S25_RS14710	COG0437	4 iron, 4 sulfur cluster binding
B9S25_RS14720	COG0697	spore germination
B9S25_RS14725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B9S25_RS14730	COG4886	Leucine-rich repeat (LRR) protein
B9S25_RS14735	COG2223	nitrite transmembrane transporter activity
B9S25_RS14740	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B9S25_RS14745	COG1140	nitrate reductase beta subunit
B9S25_RS14750	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B9S25_RS14755	COG2181	nitrate reductase activity
B9S25_RS14760	COG0384	phenazine biosynthesis protein PhzF
B9S25_RS14765	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B9S25_RS14770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B9S25_RS14800	COG3209	COG3209 Rhs family protein
B9S25_RS14815	COG0625	glutathione transferase activity
B9S25_RS14820	COG1113	amino acid transport
B9S25_RS14825	COG3391	amine dehydrogenase activity
B9S25_RS14830	COG4772	TonB-dependent receptor
B9S25_RS14835	COG1802	Transcriptional regulator
B9S25_RS14840	COG2130	NADP-dependent
B9S25_RS14845	COG1247	-acetyltransferase
B9S25_RS14850	COG3238	Protein conserved in bacteria
B9S25_RS14880	COG1177	transmembrane transport
B9S25_RS14885	COG1176	ABC-type spermidine putrescine transport system, permease component I
B9S25_RS14890	COG3842	ATPase activity
B9S25_RS14895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B9S25_RS14905	COG1598	PFAM Uncharacterised protein family UPF0150
B9S25_RS14910	COG1724	mRNA binding
B9S25_RS14920	COG0826	peptidase U32
B9S25_RS14925	COG1396	sequence-specific DNA binding
B9S25_RS14930	COG3135	benzoate transporter
B9S25_RS14935	COG0675	Transposase, IS605 OrfB family
B9S25_RS14950	COG0500	methyltransferase
B9S25_RS14955	COG1275	C4-dicarboxylate transporter malic acid transport protein
B9S25_RS14960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B9S25_RS14965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9S25_RS14970	COG2841	Protein conserved in bacteria
B9S25_RS14980	COG5383	Protein conserved in bacteria
B9S25_RS14985	COG0583	DNA-binding transcription factor activity
B9S25_RS14990	COG0840	transmembrane signaling receptor activity
B9S25_RS15005	COG3038	cytochrome b561
B9S25_RS15010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B9S25_RS15015	COG1012	belongs to the aldehyde dehydrogenase family
B9S25_RS15020	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B9S25_RS15025	COG1643	Atp-dependent helicase
B9S25_RS15035	COG2453	phosphatase
B9S25_RS15035	COG0671	phosphoesterase, PA-phosphatase related
B9S25_RS15040	COG2267	carboxylic ester hydrolase activity
B9S25_RS15045	COG4589	Belongs to the CDS family
B9S25_RS15050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B9S25_RS15060	COG0667	Aldo Keto reductase
B9S25_RS15065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B9S25_RS15070	COG3327	negative regulation of DNA-templated transcription, initiation
B9S25_RS15075	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
B9S25_RS15080	COG0183	Belongs to the thiolase family
B9S25_RS15085	COG2050	protein possibly involved in aromatic compounds catabolism
B9S25_RS15090	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9S25_RS15095	COG1024	Enoyl-CoA hydratase
B9S25_RS15100	COG1024	Enoyl-CoA hydratase
B9S25_RS15105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B9S25_RS15110	COG2151	metal-sulfur cluster biosynthetic enzyme
B9S25_RS15115	COG3396	Phenylacetate-CoA oxygenase
B9S25_RS15120	COG3460	Phenylacetate-CoA oxygenase
B9S25_RS15125	COG3396	Phenylacetate-CoA oxygenase
B9S25_RS15130	COG1012	belongs to the aldehyde dehydrogenase family
B9S25_RS15130	COG2030	dehydratase
B9S25_RS15135	COG3733	amine oxidase
B9S25_RS15140	COG1012	belongs to the aldehyde dehydrogenase family
B9S25_RS15145	COG2207	Transcriptional regulator
B9S25_RS15150	COG3784	Protein of unknown function (DUF1318)
B9S25_RS15160	COG2911	Protein conserved in bacteria
B9S25_RS15165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B9S25_RS15170	COG3187	Heat shock protein
B9S25_RS15175	COG3042	response to heat
B9S25_RS15180	COG0674	pyruvate-flavodoxin oxidoreductase activity
B9S25_RS15180	COG1013	pyruvate-flavodoxin oxidoreductase activity
B9S25_RS15180	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9S25_RS15180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B9S25_RS15185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B9S25_RS15190	COG0589	response to stress
B9S25_RS15220	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS15305	COG1030	water channel activity
B9S25_RS15325	COG4220	transposase activity
B9S25_RS15345	COG3772	lysozyme
B9S25_RS15370	COG0484	heat shock protein binding
B9S25_RS15375	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B9S25_RS15380	COG1403	HNH endonuclease
B9S25_RS15440	COG1846	Transcriptional regulator
B9S25_RS15445	COG1484	DNA-dependent DNA replication
B9S25_RS15450	COG3756	Protein conserved in bacteria
B9S25_RS15495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS15500	COG3723	Recombinational DNA repair protein, rece pathway
B9S25_RS15520	COG0582	viral genome integration into host DNA
B9S25_RS15530	COG0513	Belongs to the DEAD box helicase family
B9S25_RS15540	COG3706	GGDEF domain
B9S25_RS15545	COG2840	Smr protein MutS2
B9S25_RS15550	COG0583	DNA-binding transcription factor activity
B9S25_RS15555	COG1473	amidohydrolase
B9S25_RS15560	COG1473	amidohydrolase
B9S25_RS15565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B9S25_RS15570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B9S25_RS15575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9S25_RS15580	COG0589	response to stress
B9S25_RS15585	COG3182	Iron-regulated membrane protein
B9S25_RS15590	COG0668	transmembrane transport
B9S25_RS15595	COG4166	transmembrane transport
B9S25_RS15600	COG0583	DNA-binding transcription factor activity
B9S25_RS15605	COG1073	alpha beta
B9S25_RS15610	COG1073	alpha beta
B9S25_RS15615	COG0702	epimerase
B9S25_RS15620	COG2866	Carboxypeptidase
B9S25_RS15625	COG4948	Mandelate Racemase Muconate Lactonizing
B9S25_RS15630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B9S25_RS15635	COG3283	Transcriptional regulator of aromatic amino acids metabolism
B9S25_RS15645	COG3106	COG3106 Predicted ATPase
B9S25_RS15650	COG1609	Transcriptional regulator
B9S25_RS15660	COG3842	ATPase activity
B9S25_RS15665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9S25_RS15670	COG1554	hydrolase, family 65, central catalytic
B9S25_RS15675	COG0673	inositol 2-dehydrogenase activity
B9S25_RS15680	COG1082	Xylose isomerase domain protein TIM barrel
B9S25_RS15685	COG1063	alcohol dehydrogenase
B9S25_RS15690	COG0395	ABC-type sugar transport system, permease component
B9S25_RS15695	COG1175	transmembrane transport
B9S25_RS15700	COG1653	transport
B9S25_RS15710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9S25_RS15720	COG1983	PspC domain protein
B9S25_RS15730	COG1842	Phage shock protein A
B9S25_RS15735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B9S25_RS15745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9S25_RS15750	COG1012	belongs to the aldehyde dehydrogenase family
B9S25_RS15755	COG1917	Cupin 2, conserved barrel domain protein
B9S25_RS15755	COG1396	sequence-specific DNA binding
B9S25_RS15760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B9S25_RS15765	COG0174	glutamine synthetase
B9S25_RS15775	COG0531	amino acid
B9S25_RS15785	COG4166	transmembrane transport
B9S25_RS15790	COG4168	peptide transport system, permease
B9S25_RS15795	COG4171	peptide transport system, permease
B9S25_RS15800	COG4172	Belongs to the ABC transporter superfamily
B9S25_RS15805	COG4172	Belongs to the ABC transporter superfamily
B9S25_RS15810	COG2852	Protein conserved in bacteria
B9S25_RS15815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B9S25_RS15835	COG5001	Diguanylate cyclase
B9S25_RS15845	COG1349	DNA-binding transcription factor activity
B9S25_RS15855	COG0023	Translation Initiation Factor
B9S25_RS15865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B9S25_RS15870	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
B9S25_RS15875	COG0671	phosphoesterase, PA-phosphatase related
B9S25_RS15885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B9S25_RS15905	COG0583	DNA-binding transcription factor activity
B9S25_RS15910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B9S25_RS15920	COG0616	signal peptide processing
B9S25_RS15925	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS15930	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
B9S25_RS15935	COG1187	pseudouridine synthase activity
B9S25_RS15940	COG0009	L-threonylcarbamoyladenylate synthase
B9S25_RS15945	COG0613	PHP domain protein
B9S25_RS15955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B9S25_RS15960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B9S25_RS15960	COG0512	Glutamine amidotransferase of anthranilate synthase
B9S25_RS15965	COG0135	phosphoribosylanthranilate isomerase activity
B9S25_RS15965	COG0134	indole-3-glycerol-phosphate synthase activity
B9S25_RS15980	COG3729	General stress protein
B9S25_RS15985	COG3685	Protein conserved in bacteria
B9S25_RS15990	COG3685	Protein conserved in bacteria
B9S25_RS16090	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS16095	COG4372	Transposase
B9S25_RS16100	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS16115	COG4372	Transposase
B9S25_RS16120	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS16255	COG3772	lysozyme
B9S25_RS16320	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B9S25_RS16325	COG1403	HNH endonuclease
B9S25_RS16370	COG1846	Transcriptional regulator
B9S25_RS16420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS16430	COG0582	viral genome integration into host DNA
B9S25_RS16435	COG1177	transmembrane transport
B9S25_RS16440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B9S25_RS16450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B9S25_RS16455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B9S25_RS16465	COG4591	ABC-type transport system involved in lipoprotein release permease component
B9S25_RS16470	COG1136	(ABC) transporter
B9S25_RS16475	COG4591	ABC-type transport system involved in lipoprotein release permease component
B9S25_RS16480	COG4763	Acyl-transferase
B9S25_RS16485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B9S25_RS16490	COG1388	LysM domain
B9S25_RS16490	COG1376	ErfK ybiS ycfS ynhG family protein
B9S25_RS16500	COG1309	transcriptional regulator
B9S25_RS16505	COG3134	Outer membrane lipoprotein
B9S25_RS16510	COG1252	NADH dehydrogenase
B9S25_RS16530	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
B9S25_RS16535	COG5633	Lipoprotein
B9S25_RS16540	COG0537	adenosine 5'-monophosphoramidase activity
B9S25_RS16545	COG4773	Receptor
B9S25_RS16550	COG1263	PTS System
B9S25_RS16550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS16555	COG0084	hydrolase, TatD family'
B9S25_RS16560	COG0470	DNA polymerase III
B9S25_RS16570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B9S25_RS16575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9S25_RS16580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9S25_RS16590	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS16595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B9S25_RS16615	COG1399	metal-binding, possibly nucleic acid-binding protein
B9S25_RS16620	COG0424	maF-like protein
B9S25_RS16625	COG0564	pseudouridine synthase activity
B9S25_RS16630	COG1530	ribonuclease E activity
B9S25_RS16635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B9S25_RS16640	COG1256	bacterial-type flagellum assembly
B9S25_RS16645	COG3951	Flagellar rod assembly protein muramidase FlgJ
B9S25_RS16645	COG1705	Flagellar rod assembly protein muramidase FlgJ
B9S25_RS16660	COG4786	Flagellar basal body rod
B9S25_RS16665	COG4787	bacterial-type flagellum-dependent cell motility
B9S25_RS16670	COG1749	Flagellar hook protein flgE
B9S25_RS16675	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B9S25_RS16680	COG1558	bacterial-type flagellum-dependent cell motility
B9S25_RS16685	COG1815	bacterial-type flagellum-dependent cell motility
B9S25_RS16690	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
B9S25_RS16695	COG2747	anti-sigma28 factor FlgM
B9S25_RS16700	COG3418	PFAM FlgN family protein
B9S25_RS16705	COG0728	peptidoglycan biosynthetic process
B9S25_RS16710	COG0673	inositol 2-dehydrogenase activity
B9S25_RS16720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9S25_RS16730	COG2999	glutathione oxidoreductase activity
B9S25_RS16765	COG3038	cytochrome b561
B9S25_RS16770	COG2353	YceI-like domain
B9S25_RS16780	COG1560	Kdo2-lipid A biosynthetic process
B9S25_RS16795	COG5645	(Lipo)protein
B9S25_RS16800	COG2943	transferase activity, transferring hexosyl groups
B9S25_RS16815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9S25_RS16820	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B9S25_RS16845	COG2197	response regulator
B9S25_RS16860	COG1462	curli production assembly transport component CsgG
B9S25_RS16870	COG3381	protein complex oligomerization
B9S25_RS16920	COG2003	Belongs to the UPF0758 family
B9S25_RS16955	COG3468	outer membrane autotransporter barrel domain protein
B9S25_RS17045	COG1475	DNA binding
B9S25_RS17050	COG3969	phosphoadenosine phosphosulfate
B9S25_RS17055	COG3969	phosphoadenosine phosphosulfate
B9S25_RS17065	COG2831	hemolysin activation secretion protein
B9S25_RS17160	COG4771	TonB-dependent receptor
B9S25_RS17225	COG1358	cellular component organization or biogenesis
B9S25_RS17260	COG4372	Transposase
B9S25_RS17265	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS17310	COG0254	rRNA binding
B9S25_RS17355	COG0829	nickel cation binding
B9S25_RS17365	COG2194	sulfuric ester hydrolase activity
B9S25_RS17370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B9S25_RS17415	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS17420	COG4372	Transposase
B9S25_RS17435	COG2826	transposase and inactivated derivatives, IS30 family
B9S25_RS17455	COG4983	Phage plasmid primase, P4 family domain protein
B9S25_RS17485	COG0582	viral genome integration into host DNA
B9S25_RS17510	COG1702	phosphate starvation-inducible protein PhoH
B9S25_RS17530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9S25_RS17540	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B9S25_RS17540	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B9S25_RS17540	COG0506	proline dehydrogenase activity
B9S25_RS17545	COG1309	transcriptional regulator
B9S25_RS17580	COG2233	PERMEase
B9S25_RS17585	COG3729	General stress protein
B9S25_RS17625	COG0243	molybdopterin cofactor binding
B9S25_RS17630	COG3005	denitrification pathway
B9S25_RS17635	COG0745	RESPONSE REGULATOR receiver
B9S25_RS17640	COG1879	ABC-type sugar transport system periplasmic component
B9S25_RS17670	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS17705	COG1185	polyribonucleotide nucleotidyltransferase activity
B9S25_RS17810	COG3772	lysozyme
B9S25_RS17930	COG4680	protein conserved in bacteria
B9S25_RS18055	COG0582	viral genome integration into host DNA
B9S25_RS18060	COG0784	Response regulator, receiver
B9S25_RS18060	COG2198	Histidine kinase
B9S25_RS18060	COG2205	protein histidine kinase activity
B9S25_RS18065	COG0348	domain, Protein
B9S25_RS18085	COG1278	Cold shock
B9S25_RS18090	COG1278	Cold shock
B9S25_RS18110	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9S25_RS18115	COG1596	polysaccharide export
B9S25_RS18120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B9S25_RS18125	COG3206	protein involved in exopolysaccharide biosynthesis
B9S25_RS18125	COG0489	protein tyrosine kinase activity
B9S25_RS18140	COG1294	oxidase, subunit
B9S25_RS18145	COG1271	oxidase subunit
B9S25_RS18150	COG1773	rubredoxin
B9S25_RS18155	COG1999	signal sequence binding
B9S25_RS18160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B9S25_RS18165	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
B9S25_RS18170	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B9S25_RS18175	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
B9S25_RS18205	COG4372	Transposase
B9S25_RS18210	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS18225	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS18365	COG3772	lysozyme
B9S25_RS18415	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B9S25_RS18420	COG1403	HNH endonuclease
B9S25_RS18480	COG1396	sequence-specific DNA binding
B9S25_RS18535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS18545	COG0582	viral genome integration into host DNA
B9S25_RS18550	COG3047	cAMP biosynthetic process
B9S25_RS18570	COG1607	acyl-coa hydrolase
B9S25_RS18580	COG2350	Protein conserved in bacteria
B9S25_RS18585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B9S25_RS18605	COG4608	Belongs to the ABC transporter superfamily
B9S25_RS18610	COG0444	Belongs to the ABC transporter superfamily
B9S25_RS18615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9S25_RS18620	COG0601	transmembrane transport
B9S25_RS18625	COG4166	transmembrane transport
B9S25_RS18630	COG2095	MarC family integral membrane protein
B9S25_RS18635	COG1454	alcohol dehydrogenase
B9S25_RS18635	COG1012	belongs to the aldehyde dehydrogenase family
B9S25_RS18645	COG1435	thymidine kinase activity
B9S25_RS18655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B9S25_RS18660	COG0745	RESPONSE REGULATOR receiver
B9S25_RS18665	COG1752	Esterase of the alpha-beta hydrolase superfamily
B9S25_RS18675	COG0788	formyltetrahydrofolate deformylase activity
B9S25_RS18695	COG2181	nitrate reductase activity
B9S25_RS18700	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B9S25_RS18705	COG1140	nitrate reductase beta subunit
B9S25_RS18710	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B9S25_RS18715	COG2223	nitrite transmembrane transporter activity
B9S25_RS18720	COG3850	Histidine kinase
B9S25_RS18725	COG2197	response regulator
B9S25_RS18730	COG4932	domain protein
B9S25_RS18735	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B9S25_RS18740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B9S25_RS18745	COG4572	Cation transport regulator
B9S25_RS18750	COG0387	Pfam Sodium calcium exchanger
B9S25_RS18790	COG2912	Transglutaminase-like superfamily
B9S25_RS18795	COG3094	Invasion gene expression up-regulator, SirB
B9S25_RS18800	COG2890	protein-(glutamine-N5) methyltransferase activity
B9S25_RS18825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B9S25_RS18830	COG0659	secondary active sulfate transmembrane transporter activity
B9S25_RS18845	COG0012	GTP binding
B9S25_RS18850	COG3468	outer membrane autotransporter barrel domain protein
B9S25_RS18855	COG3284	Transcriptional regulator
B9S25_RS18860	COG2376	Dihydroxyacetone kinase
B9S25_RS18865	COG1461	Dihydroxyacetone kinase
B9S25_RS18870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS18870	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
B9S25_RS18870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9S25_RS18890	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B9S25_RS18900	COG1619	proteins homologs of microcin C7 resistance protein MccF
B9S25_RS18910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B9S25_RS18920	COG2719	SpoVR family
B9S25_RS18945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B9S25_RS18960	COG0179	Fumarylacetoacetate (FAA) hydrolase
B9S25_RS18985	COG2894	cell division
B9S25_RS19040	COG2200	EAL domain
B9S25_RS19065	COG2200	EAL domain
B9S25_RS19070	COG0789	Transcriptional regulator
B9S25_RS19075	COG5562	phage envelope protein
B9S25_RS19090	COG0538	isocitrate dehydrogenase activity
B9S25_RS19095	COG1187	pseudouridine synthase activity
B9S25_RS19115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B9S25_RS19125	COG2205	protein histidine kinase activity
B9S25_RS19135	COG4220	transposase activity
B9S25_RS19225	COG2850	peptidyl-arginine hydroxylation
B9S25_RS19285	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS19415	COG3772	lysozyme
B9S25_RS19465	COG2207	Transcriptional regulator
B9S25_RS19480	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B9S25_RS19485	COG1403	HNH endonuclease
B9S25_RS19560	COG1846	Transcriptional regulator
B9S25_RS19570	COG3756	Protein conserved in bacteria
B9S25_RS19630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS19645	COG0670	Belongs to the BI1 family
B9S25_RS19650	COG2920	part of a sulfur-relay system
B9S25_RS19655	COG1254	Belongs to the acylphosphatase family
B9S25_RS19670	COG1832	CoA-binding protein
B9S25_RS19685	COG0210	DNA helicase
B9S25_RS19690	COG3304	Inner membrane component domain
B9S25_RS19695	COG1289	transmembrane transporter activity
B9S25_RS19700	COG3070	regulator of competence-specific genes
B9S25_RS19710	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B9S25_RS19710	COG2885	chlorophyll binding
B9S25_RS19720	COG1067	ATP-dependent peptidase activity
B9S25_RS19730	COG3130	regulation of translation
B9S25_RS19735	COG3009	Protein conserved in bacteria
B9S25_RS19740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B9S25_RS19740	COG3008	intermembrane lipid transfer
B9S25_RS19745	COG2995	paraquat-inducible protein a
B9S25_RS19750	COG0488	(ABC) transporter
B9S25_RS19760	COG0633	Ferredoxin
B9S25_RS19760	COG3217	Mosc domain protein beta barrel domain protein
B9S25_RS19775	COG3121	Chaperone
B9S25_RS19780	COG3539	Fimbrial protein
B9S25_RS19785	COG3539	Fimbrial protein
B9S25_RS19790	COG3539	Fimbrial protein
B9S25_RS19795	COG3188	usher protein
B9S25_RS19800	COG3121	Chaperone
B9S25_RS19805	COG3539	Fimbrial protein
B9S25_RS19810	COG0431	NADPH-dependent FMN reductase
B9S25_RS19815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B9S25_RS19825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B9S25_RS19835	COG0308	aminopeptidase N
B9S25_RS19855	COG1448	Aminotransferase
B9S25_RS19865	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS19870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9S25_RS19875	COG3108	Peptidase M15
B9S25_RS19880	COG2989	Protein conserved in bacteria
B9S25_RS19890	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
B9S25_RS19900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9S25_RS19905	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B9S25_RS19910	COG3173	Aminoglycoside phosphotransferase
B9S25_RS19925	COG3214	Protein conserved in bacteria
B9S25_RS19935	COG1132	(ABC) transporter
B9S25_RS19940	COG2333	competence protein COMEC
B9S25_RS19940	COG0658	competence protein
B9S25_RS19950	COG0539	negative regulation of cytoplasmic translation
B9S25_RS19960	COG0501	Belongs to the peptidase M48B family
B9S25_RS19975	COG2323	membrane
B9S25_RS19980	COG1944	ATP diphosphatase activity
B9S25_RS19985	COG2116	formate transmembrane transporter activity
B9S25_RS19990	COG1882	Formate acetyltransferase
B9S25_RS19995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B9S25_RS20000	COG2249	NAD(P)H dehydrogenase (quinone) activity
B9S25_RS20005	COG0583	DNA-binding transcription factor activity
B9S25_RS20010	COG0531	amino acid
B9S25_RS20020	COG1335	isochorismatase
B9S25_RS20025	COG3302	dmso reductase anchor subunit
B9S25_RS20030	COG0437	4 iron, 4 sulfur cluster binding
B9S25_RS20035	COG0243	molybdopterin cofactor binding
B9S25_RS20045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B9S25_RS20060	COG1522	sequence-specific DNA binding
B9S25_RS20065	COG0492	ferredoxin-NADP+ reductase activity
B9S25_RS20070	COG4988	ABC transporter
B9S25_RS20075	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B9S25_RS20100	COG0542	response to heat
B9S25_RS20110	COG1278	Cold shock
B9S25_RS20115	COG1136	(ABC) transporter
B9S25_RS20115	COG0577	efflux transmembrane transporter activity
B9S25_RS20120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9S25_RS20125	COG2990	Protein conserved in bacteria
B9S25_RS20130	COG3593	DNA synthesis involved in DNA repair
B9S25_RS20140	COG2431	L-lysine efflux transmembrane transporter activity
B9S25_RS20150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B9S25_RS20155	COG0028	Belongs to the TPP enzyme family
B9S25_RS20160	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
B9S25_RS20165	COG0702	epimerase
B9S25_RS20170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9S25_RS20175	COG3023	N-Acetylmuramoyl-L-alanine amidase
B9S25_RS20190	COG1126	abc transporter atp-binding protein
B9S25_RS20195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S25_RS20200	COG4215	(ABC) transporter
B9S25_RS20205	COG4160	amino acid transport
B9S25_RS20210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S25_RS20225	COG1177	transmembrane transport
B9S25_RS20230	COG1176	ABC-type spermidine putrescine transport system, permease component I
B9S25_RS20235	COG3842	ATPase activity
B9S25_RS20240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B9S25_RS20255	COG0778	Nitroreductase
B9S25_RS20265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B9S25_RS20280	COG3226	Transcriptional regulator
B9S25_RS20285	COG0738	Major facilitator superfamily
B9S25_RS20290	COG0561	phosphatase activity
B9S25_RS20300	COG2814	Major facilitator Superfamily
B9S25_RS20305	COG0671	phosphoesterase, PA-phosphatase related
B9S25_RS20310	COG1349	DNA-binding transcription factor activity
B9S25_RS20315	COG1686	Belongs to the peptidase S11 family
B9S25_RS20320	COG0625	glutathione transferase activity
B9S25_RS20325	COG2133	pyrroloquinoline quinone binding
B9S25_RS20340	COG2199	diguanylate cyclase activity
B9S25_RS20345	COG2200	EAL domain
B9S25_RS20370	COG1446	asparaginase
B9S25_RS20375	COG0303	'Molybdopterin
B9S25_RS20380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B9S25_RS20385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B9S25_RS20390	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B9S25_RS20395	COG1882	Formate acetyltransferase
B9S25_RS20400	COG0561	phosphatase activity
B9S25_RS20410	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS20420	COG0488	(ABC) transporter
B9S25_RS20425	COG1376	ErfK ybiS ycfS ynhG family protein
B9S25_RS20430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B9S25_RS20435	COG1321	iron dependent repressor
B9S25_RS20445	COG2194	sulfuric ester hydrolase activity
B9S25_RS20450	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B9S25_RS20460	COG5006	permease, DMT superfamily
B9S25_RS20470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S25_RS20475	COG0765	amino acid transport
B9S25_RS20480	COG1126	abc transporter atp-binding protein
B9S25_RS20485	COG0668	transmembrane transport
B9S25_RS20500	COG4774	siderophore transport
B9S25_RS20510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B9S25_RS20525	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS20530	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
B9S25_RS20535	COG1199	ATP-dependent helicase activity
B9S25_RS20540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B9S25_RS20545	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B9S25_RS20550	COG0513	Belongs to the DEAD box helicase family
B9S25_RS20555	COG1309	transcriptional regulator
B9S25_RS20565	COG1131	(ABC) transporter
B9S25_RS20570	COG0842	Transport permease protein
B9S25_RS20575	COG0842	Transport permease protein
B9S25_RS20585	COG3568	Endonuclease Exonuclease Phosphatase
B9S25_RS20590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9S25_RS20595	COG0392	lysyltransferase activity
B9S25_RS20600	COG0670	Belongs to the BI1 family
B9S25_RS20605	COG0670	Belongs to the BI1 family
B9S25_RS20610	COG0314	molybdopterin synthase activity
B9S25_RS20615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B9S25_RS20625	COG0521	Mo-molybdopterin cofactor biosynthetic process
B9S25_RS20635	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B9S25_RS20645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B9S25_RS20650	COG2226	methyltransferase
B9S25_RS20665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B9S25_RS20670	COG1881	PFAM PEBP family protein
B9S25_RS20700	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS20705	COG4372	Transposase
B9S25_RS20830	COG4372	Transposase
B9S25_RS20835	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS20865	COG4220	transposase activity
B9S25_RS20885	COG3772	lysozyme
B9S25_RS21110	COG0582	viral genome integration into host DNA
B9S25_RS21115	COG4677	pectinesterase activity
B9S25_RS21120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B9S25_RS21125	COG0471	metal ion transport
B9S25_RS21130	COG2828	Protein conserved in bacteria
B9S25_RS21135	COG0583	DNA-binding transcription factor activity
B9S25_RS21145	COG0561	phosphatase activity
B9S25_RS21155	COG4149	molybdate abc transporter
B9S25_RS21160	COG0725	ABC transporter, periplasmic molybdate-binding protein
B9S25_RS21170	COG3585	molybdate ion transport
B9S25_RS21170	COG2005	Transcriptional regulator
B9S25_RS21175	COG1119	ATPase activity
B9S25_RS21180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B9S25_RS21185	COG1085	galactose-1-phosphate uridylyltransferase
B9S25_RS21195	COG2017	converts alpha-aldose to the beta-anomer
B9S25_RS21205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B9S25_RS21215	COG1230	cation diffusion facilitator family transporter
B9S25_RS21220	COG3201	nicotinamide mononucleotide transporter
B9S25_RS21270	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
B9S25_RS21275	COG2885	chlorophyll binding
B9S25_RS21285	COG3064	Membrane
B9S25_RS21290	COG0848	biopolymer transport protein
B9S25_RS21295	COG0811	peptide transport
B9S25_RS21300	COG0824	Thioesterase
B9S25_RS21305	COG3790	cyd operon protein YbgE
B9S25_RS21310	COG4890	Cyd operon protein YbgT
B9S25_RS21315	COG1294	oxidase, subunit
B9S25_RS21320	COG1271	oxidase subunit
B9S25_RS21325	COG0383	alpha-mannosidase activity
B9S25_RS21330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS21330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS21330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS21335	COG2188	Transcriptional regulator
B9S25_RS21340	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B9S25_RS21350	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9S25_RS21355	COG0567	Dehydrogenase, E1 component
B9S25_RS21360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B9S25_RS21365	COG1053	succinate dehydrogenase
B9S25_RS21370	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B9S25_RS21375	COG2009	succinate dehydrogenase
B9S25_RS21385	COG0372	Belongs to the citrate synthase family
B9S25_RS21390	COG3539	Fimbrial protein
B9S25_RS21395	COG3188	usher protein
B9S25_RS21400	COG3121	Chaperone
B9S25_RS21405	COG3539	Fimbrial protein
B9S25_RS21410	COG3180	Ammonia monooxygenase
B9S25_RS21425	COG1984	allophanate hydrolase subunit 2
B9S25_RS21430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B9S25_RS21435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B9S25_RS21445	COG0415	Belongs to the DNA photolyase family
B9S25_RS21450	COG3272	Protein of unknown function (DUF1722)
B9S25_RS21475	COG3209	COG3209 Rhs family protein
B9S25_RS21505	COG2205	protein histidine kinase activity
B9S25_RS21510	COG0745	RESPONSE REGULATOR receiver
B9S25_RS21525	COG1982	Orn Lys Arg decarboxylase major
B9S25_RS21530	COG0531	amino acid
B9S25_RS21535	COG0033	Phosphoglucomutase
B9S25_RS21540	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
B9S25_RS21545	COG0596	Alpha beta hydrolase
B9S25_RS21555	COG0716	FMN binding
B9S25_RS21565	COG0735	belongs to the Fur family
B9S25_RS21585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS21585	COG2190	(PTS) system
B9S25_RS21585	COG1263	PTS System
B9S25_RS21595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B9S25_RS21600	COG1846	Transcriptional regulator
B9S25_RS21600	COG1940	carbohydrate kinase activity
B9S25_RS21605	COG0647	UMP catabolic process
B9S25_RS21610	COG0367	asparagine synthase
B9S25_RS21650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9S25_RS21660	COG1702	phosphate starvation-inducible protein PhoH
B9S25_RS21670	COG4535	Mg2 and Co2 transporter CorC
B9S25_RS21675	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B9S25_RS21690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9S25_RS21695	COG0765	amino acid transport
B9S25_RS21700	COG0765	amino acid transport
B9S25_RS21705	COG1126	abc transporter atp-binding protein
B9S25_RS21715	COG0443	Heat shock 70 kDa protein
B9S25_RS21720	COG2214	Heat shock protein DnaJ domain protein
B9S25_RS21730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B9S25_RS21735	COG2214	Heat shock protein DnaJ domain protein
B9S25_RS21745	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B9S25_RS21750	COG2888	peptidyl-tyrosine sulfation
B9S25_RS21765	COG1466	dna polymerase III delta subunit
B9S25_RS21775	COG0406	alpha-ribazole phosphatase activity
B9S25_RS21780	COG0799	negative regulation of ribosome biogenesis
B9S25_RS21790	COG0768	penicillin binding
B9S25_RS21795	COG0772	Belongs to the SEDS family
B9S25_RS21800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B9S25_RS21805	COG1686	Belongs to the peptidase S11 family
B9S25_RS21820	COG0583	DNA-binding transcription factor activity
B9S25_RS21830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9S25_RS21835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9S25_RS21855	COG3069	C4-dicarboxylate transmembrane transporter activity
B9S25_RS21860	COG4565	transcriptional regulatory protein
B9S25_RS21865	COG3290	protein histidine kinase activity
B9S25_RS21870	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
B9S25_RS21880	COG2301	Belongs to the HpcH HpaI aldolase family
B9S25_RS21885	COG3051	citrate lyase alpha subunit
B9S25_RS21900	COG0471	metal ion transport
B9S25_RS21905	COG3719	Belongs to the RNase T2 family
B9S25_RS21910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9S25_RS21915	COG1063	alcohol dehydrogenase
B9S25_RS21920	COG0589	response to stress
B9S25_RS21925	COG3634	alkyl hydroperoxide reductase activity
B9S25_RS21930	COG0450	alkyl hydroperoxide reductase
B9S25_RS21935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B9S25_RS21940	COG0583	DNA-binding transcription factor activity
B9S25_RS21945	COG3969	phosphoadenosine phosphosulfate
B9S25_RS21950	COG1475	DNA binding
B9S25_RS21955	COG0436	Aminotransferase
B9S25_RS21960	COG0371	Dehydrogenase
B9S25_RS21965	COG2879	small protein
B9S25_RS21970	COG1966	Carbon starvation protein
B9S25_RS21975	COG2050	protein possibly involved in aromatic compounds catabolism
B9S25_RS21980	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS21985	COG1535	isochorismatase
B9S25_RS21985	COG3433	isochorismatase activity
B9S25_RS21990	COG1021	2,3-dihydroxybenzoate-AMP ligase
B9S25_RS21995	COG1169	isochorismate synthase
B9S25_RS22000	COG4592	Periplasmic binding protein
B9S25_RS22010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S25_RS22015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S25_RS22020	COG1120	ATPase activity
B9S25_RS22025	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
B9S25_RS22030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9S25_RS22030	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B9S25_RS22035	COG3251	PFAM MbtH domain protein
B9S25_RS22040	COG2382	esterase
B9S25_RS22045	COG4771	TonB-dependent receptor
B9S25_RS22050	COG2977	Belongs to the P-Pant transferase superfamily
B9S25_RS22085	COG2315	Protein conserved in bacteria
B9S25_RS22090	COG0778	Nitroreductase
B9S25_RS22095	COG0668	transmembrane transport
B9S25_RS22100	COG1113	amino acid transport
B9S25_RS22105	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9S25_RS22110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9S25_RS22115	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9S25_RS22120	COG1538	Outer membrane efflux protein
B9S25_RS22125	COG0745	RESPONSE REGULATOR receiver
B9S25_RS22130	COG5002	protein histidine kinase activity
B9S25_RS22135	COG3501	Rhs element vgr protein
B9S25_RS22145	COG3209	COG3209 Rhs family protein
B9S25_RS22145	COG4104	PAAR repeat-containing protein
B9S25_RS22160	COG4104	PAAR repeat-containing protein
B9S25_RS22160	COG3209	COG3209 Rhs family protein
B9S25_RS22165	COG5433	transposase activity
B9S25_RS22170	COG1215	transferase activity, transferring glycosyl groups
B9S25_RS22175	COG4783	chaperone-mediated protein folding
B9S25_RS22185	COG2207	Transcriptional regulator
B9S25_RS22190	COG4571	Outer membrane protease
B9S25_RS22205	COG0500	methyltransferase
B9S25_RS22215	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B9S25_RS22220	COG5301	cellulose 1,4-beta-cellobiosidase activity
B9S25_RS22255	COG1196	nuclear chromosome segregation
B9S25_RS22315	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS22320	COG4372	Transposase
B9S25_RS22345	COG4220	transposase activity
B9S25_RS22370	COG3772	lysozyme
B9S25_RS22535	COG0582	viral genome integration into host DNA
B9S25_RS22545	COG2197	response regulator
B9S25_RS22550	COG3539	Fimbrial protein
B9S25_RS22555	COG3539	Fimbrial protein
B9S25_RS22560	COG3188	usher protein
B9S25_RS22565	COG3121	Chaperone
B9S25_RS22570	COG3539	Fimbrial protein
B9S25_RS22580	COG2501	S4 domain
B9S25_RS22585	COG1988	membrane-bound metal-dependent
B9S25_RS22595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B9S25_RS22605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B9S25_RS22610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B9S25_RS22615	COG0549	Belongs to the carbamate kinase family
B9S25_RS22625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B9S25_RS22630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B9S25_RS22635	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B9S25_RS22640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9S25_RS22645	COG3257	ureidoglycine aminohydrolase activity
B9S25_RS22650	COG1929	Belongs to the glycerate kinase type-1 family
B9S25_RS22665	COG1953	Uracil, thiamine, allantoin
B9S25_RS22670	COG2084	Dehydrogenase
B9S25_RS22675	COG3622	Belongs to the hyi family
B9S25_RS22680	COG3960	tartronate-semialdehyde synthase activity
B9S25_RS22685	COG1414	Transcriptional regulator
B9S25_RS22695	COG0583	DNA-binding transcription factor activity
B9S25_RS22720	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B9S25_RS22725	COG4181	ATPase activity
B9S25_RS22730	COG2755	lipolytic protein G-D-S-L family
B9S25_RS22735	COG0300	oxidoreductase activity
B9S25_RS22740	COG3118	belongs to the thioredoxin family
B9S25_RS22745	COG0390	transport system, permease component
B9S25_RS22750	COG4619	ABC transporter
B9S25_RS22755	COG0330	HflC and HflK could
B9S25_RS22760	COG1585	Membrane protein implicated in regulation of membrane protease activity
B9S25_RS22765	COG0789	Transcriptional regulator
B9S25_RS22770	COG0531	amino acid
B9S25_RS22780	COG2217	Heavy metal translocating P-type atpase
B9S25_RS22785	COG3093	addiction module antidote protein HigA
B9S25_RS22795	COG3735	TraB family
B9S25_RS22800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B9S25_RS22805	COG0737	Belongs to the 5'-nucleotidase family
B9S25_RS22810	COG2223	nitrite transmembrane transporter activity
B9S25_RS22815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B9S25_RS22815	COG4651	solute:proton antiporter activity
B9S25_RS22820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S25_RS22855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B9S25_RS22865	COG2832	Protein of unknown function (DUF454)
B9S25_RS22870	COG3923	Primosomal replication protein n
B9S25_RS22880	COG3264	Mechanosensitive ion channel
B9S25_RS22880	COG1196	nuclear chromosome segregation
B9S25_RS22885	COG1309	transcriptional regulator
B9S25_RS22890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9S25_RS22895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9S25_RS22910	COG0110	maltose O-acetyltransferase activity
B9S25_RS22920	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B9S25_RS22925	COG5507	3-demethylubiquinone-9 3-methyltransferase
B9S25_RS22935	COG3695	enzyme binding
B9S25_RS22940	COG3126	Type III secretion system lipoprotein chaperone (YscW)
B9S25_RS22945	COG1946	Acyl-CoA thioesterase
B9S25_RS22950	COG0004	ammonium transporteR
B9S25_RS22955	COG0347	Belongs to the P(II) protein family
B9S25_RS22960	COG1132	(ABC) transporter
B9S25_RS22965	COG1132	(ABC) transporter
B9S25_RS22970	COG1522	sequence-specific DNA binding
B9S25_RS22980	COG4533	DNA binding
B9S25_RS22990	COG0824	Thioesterase
B9S25_RS22995	COG1555	photosystem II stabilization
B9S25_RS23000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B9S25_RS23005	COG0776	regulation of translation
B9S25_RS23010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B9S25_RS23030	COG0271	Belongs to the BolA IbaG family
B9S25_RS23035	COG3056	Lipoprotein
B9S25_RS23040	COG2223	nitrite transmembrane transporter activity
B9S25_RS23045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B9S25_RS23050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9S25_RS23055	COG1845	cytochrome c oxidase, subunit III
B9S25_RS23060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B9S25_RS23085	COG2814	Major facilitator Superfamily
B9S25_RS23095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B9S25_RS23100	COG0693	protein deglycase activity
B9S25_RS23115	COG0142	geranyltranstransferase activity
B9S25_RS23125	COG0667	Aldo Keto reductase
B9S25_RS23130	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B9S25_RS23135	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B9S25_RS23150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9S25_RS23150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9S25_RS23160	COG4238	major outer membrane lipoprotein
B9S25_RS23165	COG3248	Nucleoside-binding outer membrane protein
B9S25_RS23170	COG1403	HNH endonuclease
B9S25_RS23175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9S25_RS23180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9S25_RS23185	COG1862	Preprotein translocase
B9S25_RS23205	COG0366	Alpha amylase catalytic
B9S25_RS23210	COG1113	amino acid transport
B9S25_RS23215	COG1114	Component of the transport system for branched-chain amino acids
B9S25_RS23220	COG5002	protein histidine kinase activity
B9S25_RS23225	COG0745	RESPONSE REGULATOR receiver
B9S25_RS23230	COG0420	3'-5' exonuclease activity
B9S25_RS23235	COG0419	ATPase involved in DNA repair
B9S25_RS23240	COG2814	Major facilitator Superfamily
B9S25_RS23245	COG1940	carbohydrate kinase activity
B9S25_RS23270	COG4126	flavin adenine dinucleotide binding
B9S25_RS23290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B9S25_RS23295	COG3706	GGDEF domain
B9S25_RS23305	COG1785	Belongs to the alkaline phosphatase family
B9S25_RS23315	COG1181	Belongs to the D-alanine--D-alanine ligase family
B9S25_RS23340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B9S25_RS23345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9S25_RS23365	COG0113	porphobilinogen synthase activity
B9S25_RS23370	COG2175	clavaminate synthase activity
B9S25_RS23375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B9S25_RS23380	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B9S25_RS23385	COG4521	taurine ABC transporter
B9S25_RS23390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B9S25_RS23395	COG1215	transferase activity, transferring glycosyl groups
B9S25_RS23425	COG3122	Protein conserved in bacteria
B9S25_RS23430	COG2814	Major facilitator Superfamily
B9S25_RS23465	COG1414	Transcriptional regulator
B9S25_RS23470	COG1609	Transcriptional regulator
B9S25_RS23475	COG3250	beta-galactosidase activity
B9S25_RS23480	COG2223	nitrite transmembrane transporter activity
B9S25_RS23485	COG2807	transmembrane transport
B9S25_RS23495	COG0288	reversible hydration of carbon dioxide
B9S25_RS23500	COG0583	DNA-binding transcription factor activity
B9S25_RS23505	COG0402	S-adenosylhomocysteine deaminase activity
B9S25_RS23510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B9S25_RS23515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9S25_RS23520	COG2079	MmgE PrpD family protein
B9S25_RS23525	COG0372	Belongs to the citrate synthase family
B9S25_RS23530	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B9S25_RS23535	COG3829	transcription factor binding
B9S25_RS23545	COG1280	lysine exporter protein (LysE YggA)
B9S25_RS23560	COG1064	alcohol dehydrogenase
B9S25_RS23570	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S25_RS23575	COG1129	ABC transporter
B9S25_RS23580	COG1879	ABC-type sugar transport system periplasmic component
B9S25_RS23590	COG0402	S-adenosylhomocysteine deaminase activity
B9S25_RS23595	COG0549	Belongs to the carbamate kinase family
B9S25_RS23600	COG1304	FMN binding
B9S25_RS23605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B9S25_RS23615	COG0666	response to abiotic stimulus
B9S25_RS23625	COG0583	DNA-binding transcription factor activity
B9S25_RS23630	COG2200	EAL domain
B9S25_RS23630	COG2771	luxR family
B9S25_RS23640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B9S25_RS23665	COG1556	Lactate utilization protein
B9S25_RS23670	COG1139	Iron-sulfur cluster binding protein
B9S25_RS23675	COG0247	lactate metabolic process
B9S25_RS23680	COG2207	Transcriptional regulator
B9S25_RS23685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9S25_RS23695	COG3059	membrane
B9S25_RS23700	COG0656	L-ascorbic acid biosynthetic process
B9S25_RS23705	COG2207	Transcriptional regulator
B9S25_RS23705	COG3708	Transcriptional regulator
B9S25_RS23710	COG1388	LysM domain
B9S25_RS23755	COG3188	usher protein
B9S25_RS23765	COG3121	Chaperone
B9S25_RS23770	COG0727	PFAM Uncharacterised protein family (UPF0153)
B9S25_RS23850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B9S25_RS23870	COG2195	Cleaves the N-terminal amino acid of tripeptides
B9S25_RS23875	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B9S25_RS23880	COG1690	Belongs to the RtcB family
B9S25_RS23885	COG0454	-acetyltransferase
B9S25_RS23900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B9S25_RS23905	COG1191	sigma factor activity
B9S25_RS23930	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B9S25_RS23940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B9S25_RS23955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B9S25_RS23980	COG4786	Flagellar basal body rod
B9S25_RS23985	COG4787	bacterial-type flagellum-dependent cell motility
B9S25_RS23990	COG1749	Flagellar hook protein flgE
B9S25_RS24000	COG1558	bacterial-type flagellum-dependent cell motility
B9S25_RS24005	COG1815	bacterial-type flagellum-dependent cell motility
B9S25_RS24035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B9S25_RS24055	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B9S25_RS24065	COG1677	Flagellar hook-basal body complex protein FliE
B9S25_RS24090	COG1987	bacterial-type flagellum assembly
B9S25_RS24120	COG0791	NLP P60 protein
B9S25_RS24125	COG3077	Addiction module antitoxin, RelB DinJ family
B9S25_RS24130	COG3041	Addiction module toxin RelE StbE family
B9S25_RS24135	COG3034	peptidoglycan biosynthetic process
B9S25_RS24140	COG0121	glutamine amidotransferase
B9S25_RS24150	COG1960	acyl-CoA dehydrogenase activity
B9S25_RS24160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9S25_RS24235	COG3157	Type VI secretion system effector, Hcp
B9S25_RS24240	COG4104	PAAR repeat-containing protein
B9S25_RS24260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9S25_RS24270	COG2226	methyltransferase
B9S25_RS24280	COG1388	LysM domain
B9S25_RS24280	COG0741	lytic transglycosylase activity
B9S25_RS24285	COG2226	methyltransferase
B9S25_RS24295	COG0583	DNA-binding transcription factor activity
B9S25_RS24300	COG0656	L-ascorbic acid biosynthetic process
B9S25_RS24335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B9S25_RS24340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B9S25_RS24345	COG2011	ABC-type metal ion transport system permease component
B9S25_RS24350	COG1464	Belongs to the NlpA lipoprotein family
B9S25_RS24360	COG1720	tRNA m6t6A37 methyltransferase activity
B9S25_RS24375	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS24385	COG3015	lipoprotein NlpE involved in copper resistance
B9S25_RS24390	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B9S25_RS24395	COG4681	YaeQ
B9S25_RS24405	COG4568	rho-dependent transcription termination
B9S25_RS24415	COG0346	lactoylglutathione lyase activity
B9S25_RS24420	COG1982	Orn Lys Arg decarboxylase major
B9S25_RS24430	COG0587	DNA-directed DNA polymerase activity
B9S25_RS24455	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9S25_RS24460	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B9S25_RS24470	COG0750	zinc metalloprotease
B9S25_RS24475	COG0575	Belongs to the CDS family
B9S25_RS24480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B9S25_RS24485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B9S25_RS24510	COG0024	Methionine aminopeptidase
B9S25_RS24525	COG1408	metallophosphoesterase
B9S25_RS24540	COG3835	regulator
B9S25_RS24545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9S25_RS24560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9S25_RS24565	COG2860	membrane
B9S25_RS24590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S25_RS24595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9S25_RS24600	COG1120	ATPase activity
B9S25_RS24605	COG4774	siderophore transport
B9S25_RS24610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9S25_RS24615	COG1643	Atp-dependent helicase
B9S25_RS24620	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B9S25_RS24630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B9S25_RS24640	COG0617	tRNA 3'-terminal CCA addition
B9S25_RS24645	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B9S25_RS24650	COG3539	Fimbrial protein
B9S25_RS24655	COG3121	Chaperone
B9S25_RS24660	COG3188	usher protein
B9S25_RS24665	COG3539	Fimbrial protein
B9S25_RS24670	COG3539	Fimbrial protein
B9S25_RS24675	COG3539	Fimbrial protein
B9S25_RS24695	COG5464	transposase or invertase
B9S25_RS24705	COG0726	polysaccharide deacetylase
B9S25_RS24710	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS24715	COG0842	Transport permease protein
B9S25_RS24720	COG1131	(ABC) transporter
B9S25_RS24725	COG0288	reversible hydration of carbon dioxide
B9S25_RS24730	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B9S25_RS24735	COG4993	Dehydrogenase
B9S25_RS24740	COG2132	Multicopper oxidase
B9S25_RS24765	COG1049	propionate catabolic process, 2-methylcitrate cycle
B9S25_RS24770	COG3064	Membrane
B9S25_RS24775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9S25_RS24780	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9S25_RS24785	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B9S25_RS24790	COG2186	Transcriptional regulator
B9S25_RS24795	COG1113	amino acid transport
B9S25_RS24800	COG3725	Membrane protein required for beta-lactamase induction
B9S25_RS24805	COG3023	N-Acetylmuramoyl-L-alanine amidase
B9S25_RS24810	COG0157	Belongs to the NadC ModD family
B9S25_RS24815	COG4969	Belongs to the N-Me-Phe pilin family
B9S25_RS24820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B9S25_RS24825	COG1459	type II secretion system
B9S25_RS24835	COG0237	dephospho-CoA kinase activity
B9S25_RS24850	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS24860	COG0494	nUDIX hydrolase
B9S25_RS24880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B9S25_RS24885	COG0849	cell division
B9S25_RS24890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B9S25_RS24895	COG1181	Belongs to the D-alanine--D-alanine ligase family
B9S25_RS24910	COG0772	Belongs to the SEDS family
B9S25_RS24925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B9S25_RS24930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B9S25_RS24935	COG0768	penicillin binding
B9S25_RS24940	COG3116	cell division
B9S25_RS24955	COG1609	Transcriptional regulator
B9S25_RS24965	COG0440	acetolactate synthase activity
B9S25_RS24970	COG0028	Belongs to the TPP enzyme family
B9S25_RS24975	COG0583	DNA-binding transcription factor activity
B9S25_RS24990	COG0473	3-isopropylmalate dehydrogenase activity
B9S25_RS25005	COG2814	Major facilitator Superfamily
B9S25_RS25020	COG4143	(ABC) transporter
B9S25_RS25025	COG1178	ABC-type Fe3 transport system permease component
B9S25_RS25035	COG0586	Pfam SNARE associated Golgi protein
B9S25_RS25040	COG4977	sequence-specific DNA binding
B9S25_RS25055	COG0235	Class ii aldolase
B9S25_RS25060	COG0417	DNA replication proofreading
B9S25_RS25070	COG0564	pseudouridine synthase activity
B9S25_RS25075	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B9S25_RS25080	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B9S25_RS25085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B9S25_RS25125	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B9S25_RS25140	COG2271	Major facilitator Superfamily
B9S25_RS25145	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B9S25_RS25150	COG0644	oxidoreductase
B9S25_RS25200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B9S25_RS25205	COG0505	Belongs to the CarA family
B9S25_RS25225	COG1047	Peptidyl-prolyl cis-trans
B9S25_RS25240	COG0196	riboflavin kinase activity
B9S25_RS25270	COG0583	DNA-binding transcription factor activity
B9S25_RS25300	COG4735	regulation of single-species biofilm formation
B9S25_RS25305	COG1584	GPR1 FUN34 yaaH family protein
B9S25_RS25310	COG0521	Mo-molybdopterin cofactor biosynthetic process
B9S25_RS25320	COG1115	amino acid carrier protein
B9S25_RS25335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B9S25_RS25345	COG0527	aspartate kinase activity
B9S25_RS25345	COG0460	homoserine dehydrogenase
B9S25_RS25355	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
B9S25_RS25365	COG0745	RESPONSE REGULATOR receiver
B9S25_RS25370	COG4452	Inner membrane protein CreD
B9S25_RS25375	COG2205	protein histidine kinase activity
B9S25_RS25380	COG0745	RESPONSE REGULATOR receiver
B9S25_RS25385	COG3045	CreA protein
B9S25_RS25390	COG2207	Transcriptional regulator
B9S25_RS25390	COG3708	Transcriptional regulator
B9S25_RS25410	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS25420	COG0741	lytic transglycosylase activity
B9S25_RS25425	COG0488	(ABC) transporter
B9S25_RS25430	COG3172	ATPase kinase involved in NAD metabolism
B9S25_RS25430	COG1056	cytidyltransferase-related domain
B9S25_RS25435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B9S25_RS25440	COG0560	Phosphoserine phosphatase
B9S25_RS25445	COG3726	membrane protein affecting hemolysin expression
B9S25_RS25480	COG1328	CTP reductase activity
B9S25_RS25485	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B9S25_RS25490	COG0084	hydrolase, TatD family'
B9S25_RS25495	COG4667	esterase of the alpha-beta hydrolase superfamily
B9S25_RS25505	COG2823	Periplasmic or secreted lipoprotein
B9S25_RS25515	COG1011	Hydrolase
B9S25_RS25520	COG0456	acetyltransferase
B9S25_RS25525	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
B9S25_RS25555	COG4114	ferric iron reductase
B9S25_RS25560	COG2197	response regulator
B9S25_RS25565	COG2197	response regulator
B9S25_RS25570	COG2966	Psort location CytoplasmicMembrane, score
B9S25_RS25585	COG1484	DNA-dependent DNA replication
B9S25_RS25600	COG1063	alcohol dehydrogenase
B9S25_RS25605	COG1802	Transcriptional regulator
B9S25_RS25610	COG0025	NhaP-type Na H and K H
B9S25_RS25615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B9S25_RS25625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B9S25_RS25630	COG0840	transmembrane signaling receptor activity
B9S25_RS25635	COG1846	Transcriptional regulator
B9S25_RS25640	COG0179	Fumarylacetoacetate (FAA) hydrolase
B9S25_RS25645	COG1012	belongs to the aldehyde dehydrogenase family
B9S25_RS25650	COG3384	dioxygenase
B9S25_RS25660	COG3971	2-oxopent-4-enoate hydratase activity
B9S25_RS25680	COG2368	4-hydroxyphenylacetate
B9S25_RS25685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B9S25_RS25690	COG1966	Carbon starvation protein
B9S25_RS25695	COG2879	small protein
B9S25_RS25700	COG0523	cobalamin synthesis protein
B9S25_RS25725	COG0732	type I restriction modification DNA specificity domain
B9S25_RS25740	COG5457	Domain of unknown function (DUF1127)
B9S25_RS25745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9S25_RS25755	COG2814	Major facilitator Superfamily
B9S25_RS25760	COG2733	membrane
B9S25_RS25765	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
B9S25_RS25770	COG1924	4 iron, 4 sulfur cluster binding
B9S25_RS25785	COG0477	Major facilitator Superfamily
B9S25_RS25795	COG3366	ferrous iron transmembrane transporter activity
B9S25_RS25800	COG0700	Nucleoside recognition
B9S25_RS25805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B9S25_RS25830	COG2186	Transcriptional regulator
B9S25_RS25835	COG0246	Mannitol dehydrogenase
B9S25_RS25850	COG3539	Fimbrial protein
B9S25_RS25855	COG3539	Fimbrial protein
B9S25_RS25860	COG3539	Fimbrial protein
B9S25_RS25865	COG3188	usher protein
B9S25_RS25870	COG3121	Chaperone
B9S25_RS25875	COG3539	Fimbrial protein
B9S25_RS25885	COG4974	Belongs to the 'phage' integrase family
B9S25_RS25890	COG0582	viral genome integration into host DNA
B9S25_RS25895	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B9S25_RS25900	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
B9S25_RS25960	COG2003	Belongs to the UPF0758 family
B9S25_RS25990	COG2020	methyltransferase activity
B9S25_RS25995	COG3468	outer membrane autotransporter barrel domain protein
B9S25_RS26010	COG4983	Phage plasmid primase, P4 family domain protein
B9S25_RS26030	COG4372	Transposase
B9S25_RS26035	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS26050	COG0602	queuosine metabolic process
B9S25_RS26055	COG1328	CTP reductase activity
B9S25_RS26060	COG0366	Alpha amylase catalytic
B9S25_RS26065	COG1263	PTS System
B9S25_RS26065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS26070	COG1609	Transcriptional regulator
B9S25_RS26080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B9S25_RS26085	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS26095	COG0251	oxidation-reduction process
B9S25_RS26115	COG0251	oxidation-reduction process
B9S25_RS26120	COG1028	Short-chain dehydrogenase reductase Sdr
B9S25_RS26125	COG1309	transcriptional regulator
B9S25_RS26130	COG2731	YhcH YjgK YiaL family protein
B9S25_RS26150	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
B9S25_RS26155	COG0456	acetyltransferase
B9S25_RS26170	COG2927	DNA polymerase III (CHI subunit)
B9S25_RS26180	COG0795	lipopolysaccharide-transporting ATPase activity
B9S25_RS26185	COG0795	lipopolysaccharide-transporting ATPase activity
B9S25_RS26190	COG0433	COG0433 Predicted ATPase
B9S25_RS26195	COG1064	alcohol dehydrogenase
B9S25_RS26205	COG0582	viral genome integration into host DNA
B9S25_RS26230	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS26235	COG4372	Transposase
B9S25_RS26295	COG2085	NADP oxidoreductase coenzyme F420-dependent
B9S25_RS26300	COG1120	ATPase activity
B9S25_RS26305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S25_RS26310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9S25_RS26315	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B9S25_RS26320	COG4772	TonB-dependent receptor
B9S25_RS26325	COG3712	iron ion homeostasis
B9S25_RS26330	COG1595	DNA-templated transcription, initiation
B9S25_RS26370	COG4372	Transposase
B9S25_RS26375	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS26405	COG4372	Transposase
B9S25_RS26410	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS26455	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS26460	COG4372	Transposase
B9S25_RS26470	COG0312	modulator of DNA gyrase
B9S25_RS26480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B9S25_RS26490	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S25_RS26495	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S25_RS26500	COG1129	ABC transporter
B9S25_RS26505	COG1879	ABC-type sugar transport system periplasmic component
B9S25_RS26510	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B9S25_RS26515	COG2337	Toxic component of a toxin-antitoxin (TA) module
B9S25_RS26520	COG2336	PFAM SpoVT AbrB
B9S25_RS26525	COG2105	PFAM AIG2 family protein
B9S25_RS26530	COG2911	Protein conserved in bacteria
B9S25_RS26535	COG0729	surface antigen
B9S25_RS26545	COG1253	flavin adenine dinucleotide binding
B9S25_RS26555	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
B9S25_RS26560	COG1218	3'(2'),5'-bisphosphate nucleotidase
B9S25_RS26565	COG0737	Belongs to the 5'-nucleotidase family
B9S25_RS26570	COG1733	regulation of RNA biosynthetic process
B9S25_RS26575	COG0702	epimerase
B9S25_RS26580	COG0697	spore germination
B9S25_RS26600	COG1113	amino acid transport
B9S25_RS26605	COG0545	Peptidyl-prolyl cis-trans isomerase
B9S25_RS26615	COG3061	Opacity-associated protein A
B9S25_RS26625	COG0675	Transposase, IS605 OrfB family
B9S25_RS26645	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B9S25_RS26690	COG3037	sugar-specific permease SgaT UlaA
B9S25_RS26705	COG1073	alpha beta
B9S25_RS26710	COG3650	response to hydrogen peroxide
B9S25_RS26720	COG1960	acyl-CoA dehydrogenase activity
B9S25_RS26725	COG0754	glutathionylspermidine amidase activity
B9S25_RS26730	COG5463	Belongs to the UPF0441 family
B9S25_RS26735	COG3766	membrane
B9S25_RS26745	COG1842	Phage shock protein A
B9S25_RS26750	COG3789	protein conserved in bacteria
B9S25_RS26755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9S25_RS26760	COG0557	exoribonuclease II activity
B9S25_RS26775	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
B9S25_RS26780	COG0330	HflC and HflK could
B9S25_RS26785	COG0330	HflC and HflK could
B9S25_RS26790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B9S25_RS26810	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9S25_RS26815	COG0802	atpase or kinase
B9S25_RS26820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B9S25_RS26820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B9S25_RS26865	COG1511	domain protein
B9S25_RS26865	COG3264	Mechanosensitive ion channel
B9S25_RS26880	COG0531	amino acid
B9S25_RS26890	COG1053	succinate dehydrogenase
B9S25_RS26895	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B9S25_RS26910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B9S25_RS26915	COG3040	lipid binding
B9S25_RS26920	COG2076	Multidrug Resistance protein
B9S25_RS26925	COG5510	response to toxic substance
B9S25_RS26930	COG5510	response to toxic substance
B9S25_RS26940	COG1509	lysine 2,3-aminomutase activity
B9S25_RS26950	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS26975	COG0531	amino acid
B9S25_RS26980	COG3030	protein affecting phage T7 exclusion by the F plasmid
B9S25_RS26985	COG1027	Aspartate ammonia-lyase
B9S25_RS26990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B9S25_RS27005	COG1309	transcriptional regulator
B9S25_RS27015	COG0582	viral genome integration into host DNA
B9S25_RS27020	COG4372	Transposase
B9S25_RS27300	COG3710	Transcriptional regulator
B9S25_RS27310	COG0531	amino acid
B9S25_RS27315	COG1982	Orn Lys Arg decarboxylase major
B9S25_RS27320	COG3104	oligopeptide transport
B9S25_RS27325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B9S25_RS27340	COG2388	GCN5-related N-acetyl-transferase
B9S25_RS27345	COG3592	Divergent 4Fe-4S mono-cluster
B9S25_RS27350	COG3290	protein histidine kinase activity
B9S25_RS27355	COG4565	transcriptional regulatory protein
B9S25_RS27360	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B9S25_RS27365	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B9S25_RS27365	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B9S25_RS27370	COG3647	Membrane
B9S25_RS27380	COG2211	Major facilitator Superfamily
B9S25_RS27385	COG1486	melibiose metabolic process
B9S25_RS27390	COG2169	Transcriptional regulator
B9S25_RS27395	COG1982	Orn Lys Arg decarboxylase major
B9S25_RS27400	COG2207	Transcriptional regulator
B9S25_RS27405	COG0531	amino acid
B9S25_RS27410	COG2194	sulfuric ester hydrolase activity
B9S25_RS27415	COG0745	RESPONSE REGULATOR receiver
B9S25_RS27420	COG0642	Histidine kinase
B9S25_RS27430	COG0477	Major facilitator Superfamily
B9S25_RS27440	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B9S25_RS27445	COG2824	Alkylphosphonate utilization operon protein PhnA
B9S25_RS27450	COG2764	glyoxalase bleomycin resistance protein dioxygenase
B9S25_RS27460	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B9S25_RS27465	COG3639	organic phosphonate transmembrane transporter activity
B9S25_RS27470	COG2188	Transcriptional regulator
B9S25_RS27475	COG3624	Phosphonate C-P lyase system protein PhnG
B9S25_RS27480	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
B9S25_RS27485	COG3626	phosphonate metabolism
B9S25_RS27490	COG3627	carbon phosphorus lyase activity
B9S25_RS27495	COG4107	phosphonate C-P lyase system protein PhnK
B9S25_RS27500	COG4778	phosphonate C-P lyase system protein PhnL
B9S25_RS27505	COG3454	Phosphonate metabolism
B9S25_RS27510	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
B9S25_RS27515	COG0456	acetyltransferase
B9S25_RS27520	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B9S25_RS27530	COG0698	ribose 5-phosphate isomerase
B9S25_RS27535	COG2015	COG2015, Alkyl sulfatase and related hydrolases
B9S25_RS27545	COG1566	PFAM secretion protein HlyD family protein
B9S25_RS27550	COG1289	transmembrane transporter activity
B9S25_RS27565	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B9S25_RS27570	COG1301	dicarboxylic acid transport
B9S25_RS27575	COG4235	cytochrome complex assembly
B9S25_RS27580	COG3088	subunit of a heme lyase
B9S25_RS27585	COG1138	Cytochrome C-type biogenesis protein
B9S25_RS27590	COG3301	Polysulphide reductase, NrfD
B9S25_RS27595	COG0437	4 iron, 4 sulfur cluster binding
B9S25_RS27600	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
B9S25_RS27610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9S25_RS27615	COG3162	membrane
B9S25_RS27630	COG0025	NhaP-type Na H and K H
B9S25_RS27635	COG2252	PERMEase
B9S25_RS27640	COG0789	Transcriptional regulator
B9S25_RS27645	COG2207	Transcriptional regulator
B9S25_RS27650	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B9S25_RS27660	COG0629	single-stranded DNA binding
B9S25_RS27665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B9S25_RS27670	COG2315	Protein conserved in bacteria
B9S25_RS27675	COG0432	Pfam Uncharacterised protein family UPF0047
B9S25_RS27680	COG3700	Belongs to the class B bacterial acid phosphatase family
B9S25_RS27690	COG1448	Aminotransferase
B9S25_RS27695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B9S25_RS27700	COG0305	Participates in initiation and elongation during chromosome replication
B9S25_RS27705	COG0604	alcohol dehydrogenase
B9S25_RS27715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B9S25_RS27730	COG0735	belongs to the Fur family
B9S25_RS27735	COG3237	CsbD-like
B9S25_RS27740	COG0534	Mate efflux family protein
B9S25_RS27750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B9S25_RS27785	COG3842	ATPase activity
B9S25_RS27795	COG2182	Extracellular solute-binding protein
B9S25_RS27800	COG1175	transmembrane transport
B9S25_RS27805	COG3833	ABC-type maltose transport systems, permease component
B9S25_RS27810	COG0477	Major facilitator Superfamily
B9S25_RS27810	COG2814	Major facilitator Superfamily
B9S25_RS27825	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9S25_RS27855	COG0527	aspartate kinase activity
B9S25_RS27860	COG0542	response to heat
B9S25_RS27865	COG3541	Predicted nucleotidyltransferase
B9S25_RS27925	COG1283	sodium-dependent phosphate transmembrane transporter activity
B9S25_RS27930	COG0646	methionine synthase
B9S25_RS27930	COG1410	methionine synthase
B9S25_RS27935	COG1414	Transcriptional regulator
B9S25_RS27950	COG2224	Isocitrate lyase
B9S25_RS27955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B9S25_RS27965	COG0456	acetyltransferase
B9S25_RS27995	COG0151	Belongs to the GarS family
B9S25_RS28000	COG2204	response regulator
B9S25_RS28005	COG4191	Histidine kinase
B9S25_RS28010	COG3678	ATP-independent chaperone mediated protein folding
B9S25_RS28025	COG3068	Protein conserved in bacteria
B9S25_RS28060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B9S25_RS28065	COG2104	thiamine diphosphate biosynthetic process
B9S25_RS28075	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B9S25_RS28115	COG0250	Participates in transcription elongation, termination and antitermination
B9S25_RS28120	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B9S25_RS28155	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B9S25_RS28155	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B9S25_RS28210	COG1309	transcriptional regulator
B9S25_RS28220	COG0583	DNA-binding transcription factor activity
B9S25_RS28235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B9S25_RS28250	COG2194	sulfuric ester hydrolase activity
B9S25_RS28255	COG2207	Transcriptional regulator
B9S25_RS28260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS28265	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B9S25_RS28270	COG1882	Formate acetyltransferase
B9S25_RS28275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS28280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS28285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9S25_RS28285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS28285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS28290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS28290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS28290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9S25_RS28295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B9S25_RS28300	COG0371	Dehydrogenase
B9S25_RS28305	COG3738	Protein conserved in bacteria
B9S25_RS28310	COG0697	spore germination
B9S25_RS28320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B9S25_RS28325	COG0527	aspartate kinase activity
B9S25_RS28325	COG0460	homoserine dehydrogenase
B9S25_RS28330	COG0626	cystathionine gamma-synthase activity
B9S25_RS28340	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
B9S25_RS28355	COG3209	COG3209 Rhs family protein
B9S25_RS28365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B9S25_RS28370	COG1609	Transcriptional regulator
B9S25_RS28375	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B9S25_RS28390	COG1575	Belongs to the MenA family. Type 1 subfamily
B9S25_RS28405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B9S25_RS28415	COG1494	fructose-1,6-bisphosphatase
B9S25_RS28425	COG0589	response to stress
B9S25_RS28430	COG3691	Protein conserved in bacteria
B9S25_RS28435	COG3152	Membrane
B9S25_RS28455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B9S25_RS28470	COG3678	ATP-independent chaperone mediated protein folding
B9S25_RS28475	COG0745	RESPONSE REGULATOR receiver
B9S25_RS28480	COG2205	protein histidine kinase activity
B9S25_RS28485	COG2258	MOSC domain
B9S25_RS28495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B9S25_RS28535	COG1454	alcohol dehydrogenase
B9S25_RS28545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS28550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS28550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9S25_RS28555	COG1363	Peptidase, m42
B9S25_RS28560	COG3711	transcriptional antiterminator
B9S25_RS28560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9S25_RS28580	COG0437	4 iron, 4 sulfur cluster binding
B9S25_RS28585	COG2864	formate dehydrogenase
B9S25_RS28600	COG3547	Transposase (IS116 IS110 IS902 family)
B9S25_RS28605	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B9S25_RS28610	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B9S25_RS28620	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
B9S25_RS28630	COG0456	acetyltransferase
B9S25_RS28645	COG1011	Hydrolase
B9S25_RS28650	COG1349	DNA-binding transcription factor activity
B9S25_RS28655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S25_RS28660	COG2084	Dehydrogenase
B9S25_RS28665	COG3684	Belongs to the aldolase LacD family
B9S25_RS28670	COG2942	2-epimerase
B9S25_RS28675	COG2017	converts alpha-aldose to the beta-anomer
B9S25_RS28680	COG1501	Belongs to the glycosyl hydrolase 31 family
B9S25_RS28685	COG2211	Major facilitator Superfamily
B9S25_RS28690	COG2211	Major facilitator Superfamily
B9S25_RS28695	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B9S25_RS28700	COG2271	Major facilitator Superfamily
B9S25_RS28705	COG1082	Xylose isomerase domain protein TIM barrel
B9S25_RS28710	COG2188	Transcriptional regulator
B9S25_RS28715	COG1217	gtp-binding protein TYPA
B9S25_RS28720	COG0174	glutamine synthetase
B9S25_RS28725	COG3852	Histidine kinase
B9S25_RS28730	COG2204	response regulator
B9S25_RS28740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B9S25_RS28755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9S25_RS28755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9S25_RS28765	COG0204	Acyl-transferase
B9S25_RS28770	COG5339	Protein conserved in bacteria
B9S25_RS28775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B9S25_RS28780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B9S25_RS28785	COG3084	Protein conserved in bacteria
B9S25_RS28790	COG0746	molybdenum cofactor guanylyltransferase activity
B9S25_RS28795	COG1763	Mo-molybdopterin cofactor biosynthetic process
B9S25_RS28825	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
B9S25_RS28830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B9S25_RS28835	COG1739	Uncharacterized protein family UPF0029
B9S25_RS28855	COG0543	2 iron, 2 sulfur cluster binding
B9S25_RS28860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B9S25_RS28865	COG0250	Participates in transcription elongation, termination and antitermination
B9S25_RS28875	COG0805	protein transport
B9S25_RS28880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9S25_RS28885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9S25_RS28895	COG3165	ubiquinone biosynthetic process from chorismate
B9S25_RS28905	COG1322	Protein conserved in bacteria
B9S25_RS28910	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
B9S25_RS28915	COG0412	Dienelactone hydrolase
B9S25_RS28925	COG0583	DNA-binding transcription factor activity
B9S25_RS28930	COG0697	spore germination
B9S25_RS28935	COG0561	phosphatase activity
B9S25_RS28940	COG2267	carboxylic ester hydrolase activity
B9S25_RS28945	COG1280	lysine exporter protein (LysE YggA)
B9S25_RS28950	COG1280	lysine exporter protein (LysE YggA)
B9S25_RS28955	COG0514	ATP-dependent DNA helicase (RecQ)
B9S25_RS28960	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
B9S25_RS28965	COG2050	protein possibly involved in aromatic compounds catabolism
B9S25_RS28970	COG2962	Rard protein
B9S25_RS29000	COG0598	Magnesium transport protein CorA
B9S25_RS29005	COG3698	Phosphodiester glycosidase
B9S25_RS29010	COG0210	DNA helicase
B9S25_RS29015	COG1011	Hydrolase
B9S25_RS29025	COG3159	Protein conserved in bacteria
B9S25_RS29035	COG5567	small periplasmic lipoprotein
B9S25_RS29060	COG3072	Adenylate cyclase
B9S25_RS29070	COG1587	Uroporphyrinogen-III synthase
B9S25_RS29075	COG2959	enzyme of heme biosynthesis
B9S25_RS29080	COG3071	HemY protein
B9S25_RS29085	COG0641	radical SAM
B9S25_RS29110	COG1113	amino acid transport
B9S25_RS29130	COG2244	polysaccharide biosynthetic process
B9S25_RS29135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B9S25_RS29140	COG0456	acetyltransferase
B9S25_RS29145	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B9S25_RS29150	COG1088	dTDP-glucose 4,6-dehydratase activity
B9S25_RS29155	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B9S25_RS29160	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B9S25_RS29165	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
B9S25_RS29170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B9S25_RS29175	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B9S25_RS29185	COG3118	belongs to the thioredoxin family
B9S25_RS29200	COG0210	DNA helicase
B9S25_RS29205	COG3692	DNA binding
B9S25_RS29210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B9S25_RS29220	COG0583	DNA-binding transcription factor activity
B9S25_RS29225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B9S25_RS29235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9S25_RS29240	COG3978	acetolactate synthase activity
B9S25_RS29260	COG0606	chelatase, subunit chli
B9S25_RS29265	COG3085	chromosome segregation
B9S25_RS29305	COG2186	Transcriptional regulator
B9S25_RS29310	COG0477	Major facilitator Superfamily
B9S25_RS29315	COG1609	Transcriptional regulator
B9S25_RS29320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9S25_RS29325	COG1879	ABC-type sugar transport system periplasmic component
B9S25_RS29330	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9S25_RS29335	COG1129	ABC transporter
B9S25_RS29365	COG1522	sequence-specific DNA binding
B9S25_RS29370	COG0716	FMN binding
B9S25_RS29385	COG3312	ion transport
B9S25_RS29435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9S25_RS29450	COG3188	usher protein
B9S25_RS29460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B9S25_RS29465	COG0573	inorganic phosphate transmembrane transporter activity
B9S25_RS29470	COG0581	inorganic phosphate transmembrane transporter activity
B9S25_RS29475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B9S25_RS29480	COG0704	Plays a role in the regulation of phosphate uptake
B9S25_RS29485	COG3711	transcriptional antiterminator
B9S25_RS29490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9S25_RS29490	COG1263	PTS System
B9S25_RS29490	COG2190	(PTS) system
B9S25_RS29495	COG2723	6-phospho-beta-galactosidase activity
B9S25_RS29505	COG2382	esterase
B9S25_RS29510	COG0363	glucosamine-6-phosphate deaminase activity
B9S25_RS29515	COG3196	Protein conserved in bacteria
B9S25_RS29525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9S25_RS29530	COG2252	PERMEase
B9S25_RS29535	COG0431	NADPH-dependent FMN reductase
B9S25_RS29540	COG2091	lysine biosynthetic process via aminoadipic acid
B9S25_RS29555	COG0814	amino acid
B9S25_RS29605	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS29610	COG4372	Transposase
B9S25_RS29630	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS29635	COG4372	Transposase
B9S25_RS29645	COG1560	Kdo2-lipid A biosynthetic process
B9S25_RS29650	COG2194	sulfuric ester hydrolase activity
B9S25_RS29655	COG0297	glycogen (starch) synthase activity
B9S25_RS29660	COG0726	polysaccharide deacetylase
B9S25_RS29690	COG2274	protein secretion by the type I secretion system
B9S25_RS29775	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS29780	COG4372	Transposase
B9S25_RS29895	COG4372	Transposase
B9S25_RS29900	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS29910	COG4372	Transposase
B9S25_RS29915	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS30100	COG4372	Transposase
B9S25_RS30105	COG3436	PFAM IS66 Orf2 family protein
B9S25_RS30125	COG1585	Membrane protein implicated in regulation of membrane protease activity
B9S25_RS30140	COG3468	outer membrane autotransporter barrel domain protein
B9S25_RS30155	COG1585	Membrane protein implicated in regulation of membrane protease activity
B9S25_RS30160	COG0270	DNA (cytosine-5-)-methyltransferase activity
B9S25_RS30215	COG1278	Cold shock