locus-tag	class	description
PCN061_RS00010	COG0460	homoserine dehydrogenase
PCN061_RS00010	COG0527	aspartate kinase activity
PCN061_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PCN061_RS00040	COG1115	amino acid carrier protein
PCN061_RS00045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PCN061_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
PCN061_RS00055	COG1584	GPR1 FUN34 yaaH family protein
PCN061_RS00060	COG4735	regulation of single-species biofilm formation
PCN061_RS00080	COG3385	transposase activity
PCN061_RS00085	COG3385	transposase activity
PCN061_RS00095	COG2801	Transposase and inactivated derivatives
PCN061_RS00100	COG2963	transposase activity
PCN061_RS00110	COG0583	DNA-binding transcription factor activity
PCN061_RS00125	COG3188	usher protein
PCN061_RS00145	COG0196	riboflavin kinase activity
PCN061_RS00160	COG1047	Peptidyl-prolyl cis-trans
PCN061_RS00190	COG0505	Belongs to the CarA family
PCN061_RS00195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PCN061_RS00250	COG0644	oxidoreductase
PCN061_RS00255	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
PCN061_RS00260	COG2271	Major facilitator Superfamily
PCN061_RS00275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PCN061_RS00300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PCN061_RS00305	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PCN061_RS00310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PCN061_RS00315	COG0564	pseudouridine synthase activity
PCN061_RS00325	COG0417	DNA replication proofreading
PCN061_RS00330	COG0235	Class ii aldolase
PCN061_RS00345	COG4977	sequence-specific DNA binding
PCN061_RS00350	COG0586	Pfam SNARE associated Golgi protein
PCN061_RS00360	COG1178	ABC-type Fe3 transport system permease component
PCN061_RS00365	COG4143	(ABC) transporter
PCN061_RS00380	COG2814	Major facilitator Superfamily
PCN061_RS00395	COG0473	3-isopropylmalate dehydrogenase activity
PCN061_RS00410	COG0583	DNA-binding transcription factor activity
PCN061_RS00415	COG0028	Belongs to the TPP enzyme family
PCN061_RS00420	COG0440	acetolactate synthase activity
PCN061_RS00430	COG1609	Transcriptional regulator
PCN061_RS00435	COG2001	Belongs to the MraZ family
PCN061_RS00445	COG3116	cell division
PCN061_RS00450	COG0768	penicillin binding
PCN061_RS00455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PCN061_RS00460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PCN061_RS00470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PCN061_RS00475	COG0772	Belongs to the SEDS family
PCN061_RS00490	COG1181	Belongs to the D-alanine--D-alanine ligase family
PCN061_RS00495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PCN061_RS00500	COG0849	cell division
PCN061_RS00505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PCN061_RS00525	COG0494	nUDIX hydrolase
PCN061_RS00545	COG0237	dephospho-CoA kinase activity
PCN061_RS00555	COG1459	type II secretion system
PCN061_RS00560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PCN061_RS00565	COG4969	Belongs to the N-Me-Phe pilin family
PCN061_RS00575	COG0157	Belongs to the NadC ModD family
PCN061_RS00580	COG3023	N-Acetylmuramoyl-L-alanine amidase
PCN061_RS00585	COG3725	Membrane protein required for beta-lactamase induction
PCN061_RS00595	COG2186	Transcriptional regulator
PCN061_RS00600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PCN061_RS00605	COG0508	dehydrogenase complex catalyzes the overall conversion of
PCN061_RS00610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCN061_RS00615	COG3064	Membrane
PCN061_RS00620	COG1049	propionate catabolic process, 2-methylcitrate cycle
PCN061_RS00645	COG2132	Multicopper oxidase
PCN061_RS00650	COG4993	Dehydrogenase
PCN061_RS00655	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PCN061_RS00660	COG0288	reversible hydration of carbon dioxide
PCN061_RS00665	COG1131	(ABC) transporter
PCN061_RS00670	COG0842	Transport permease protein
PCN061_RS00675	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS00680	COG0726	polysaccharide deacetylase
PCN061_RS00690	COG5464	transposase or invertase
PCN061_RS00725	COG3539	Fimbrial protein
PCN061_RS00730	COG3539	Fimbrial protein
PCN061_RS00735	COG3188	usher protein
PCN061_RS00740	COG1662	PFAM IS1 transposase
PCN061_RS00745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PCN061_RS00750	COG0617	tRNA 3'-terminal CCA addition
PCN061_RS00760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PCN061_RS00770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PCN061_RS00775	COG1643	Atp-dependent helicase
PCN061_RS00785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PCN061_RS00790	COG4774	siderophore transport
PCN061_RS00795	COG1120	ATPase activity
PCN061_RS00800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PCN061_RS00805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCN061_RS00825	COG2860	membrane
PCN061_RS00830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PCN061_RS00845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PCN061_RS00850	COG3835	regulator
PCN061_RS00860	COG1408	metallophosphoesterase
PCN061_RS00875	COG0024	Methionine aminopeptidase
PCN061_RS00900	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PCN061_RS00905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PCN061_RS00910	COG0575	Belongs to the CDS family
PCN061_RS00915	COG0750	zinc metalloprotease
PCN061_RS00925	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
PCN061_RS00930	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCN061_RS00955	COG0587	DNA-directed DNA polymerase activity
PCN061_RS00965	COG1982	Orn Lys Arg decarboxylase major
PCN061_RS00970	COG0346	lactoylglutathione lyase activity
PCN061_RS00975	COG0037	tRNA processing
PCN061_RS00980	COG4568	rho-dependent transcription termination
PCN061_RS00990	COG4681	YaeQ
PCN061_RS00995	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PCN061_RS01000	COG3015	lipoprotein NlpE involved in copper resistance
PCN061_RS01005	COG0791	NLP P60 protein
PCN061_RS01010	COG0791	NLP P60 protein
PCN061_RS01020	COG1720	tRNA m6t6A37 methyltransferase activity
PCN061_RS01030	COG1464	Belongs to the NlpA lipoprotein family
PCN061_RS01035	COG2011	ABC-type metal ion transport system permease component
PCN061_RS01040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCN061_RS01045	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PCN061_RS01080	COG0656	L-ascorbic acid biosynthetic process
PCN061_RS01085	COG0583	DNA-binding transcription factor activity
PCN061_RS01095	COG2226	methyltransferase
PCN061_RS01100	COG1388	LysM domain
PCN061_RS01100	COG0741	lytic transglycosylase activity
PCN061_RS01110	COG2226	methyltransferase
PCN061_RS01120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PCN061_RS01145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PCN061_RS01155	COG1960	acyl-CoA dehydrogenase activity
PCN061_RS01165	COG0121	glutamine amidotransferase
PCN061_RS01170	COG3034	peptidoglycan biosynthetic process
PCN061_RS01175	COG3041	Addiction module toxin RelE StbE family
PCN061_RS01180	COG3077	Addiction module antitoxin, RelB DinJ family
PCN061_RS01185	COG0791	NLP P60 protein
PCN061_RS01190	COG1943	Transposase
PCN061_RS01210	COG2161	toxin-antitoxin pair type II binding
PCN061_RS01220	COG0454	-acetyltransferase
PCN061_RS01225	COG1690	Belongs to the RtcB family
PCN061_RS01235	COG2195	Cleaves the N-terminal amino acid of tripeptides
PCN061_RS01255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PCN061_RS01275	COG0582	viral genome integration into host DNA
PCN061_RS01290	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PCN061_RS01335	COG1846	Transcriptional regulator
PCN061_RS01350	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
PCN061_RS01360	COG1403	HNH endonuclease
PCN061_RS01415	COG1802	Transcriptional regulator
PCN061_RS01415	COG4626	Terminase
PCN061_RS01425	COG4695	Portal protein
PCN061_RS01470	COG4386	tail sheath protein
PCN061_RS01490	COG4228	DNA circulation
PCN061_RS01510	COG3299	homolog of phage Mu protein gp47
PCN061_RS01515	COG3778	Protein conserved in bacteria
PCN061_RS01540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PCN061_RS01565	COG1192	Involved in chromosome partitioning
PCN061_RS01575	COG2801	Transposase and inactivated derivatives
PCN061_RS01605	COG0823	Involved in the tonB-independent uptake of proteins
PCN061_RS01610	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS01615	COG1917	Cupin 2, conserved barrel domain protein
PCN061_RS01620	COG2211	Major facilitator Superfamily
PCN061_RS01645	COG3039	Transposase
PCN061_RS01670	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS01695	COG4626	Terminase
PCN061_RS01695	COG1802	Transcriptional regulator
PCN061_RS01730	COG1388	LysM domain
PCN061_RS01735	COG3708	Transcriptional regulator
PCN061_RS01735	COG2207	Transcriptional regulator
PCN061_RS01745	COG3436	PFAM IS66 Orf2 family protein
PCN061_RS01750	COG4372	Transposase
PCN061_RS01755	COG3708	Transcriptional regulator
PCN061_RS01755	COG2207	Transcriptional regulator
PCN061_RS01760	COG3059	membrane
PCN061_RS01770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCN061_RS01775	COG2207	Transcriptional regulator
PCN061_RS01780	COG0247	lactate metabolic process
PCN061_RS01785	COG1139	Iron-sulfur cluster binding protein
PCN061_RS01790	COG1556	Lactate utilization protein
PCN061_RS01830	COG0640	Transcriptional regulator
PCN061_RS01845	COG0786	glutamate:sodium symporter activity
PCN061_RS01870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PCN061_RS01885	COG2801	Transposase and inactivated derivatives
PCN061_RS01890	COG2200	EAL domain
PCN061_RS01890	COG2771	luxR family
PCN061_RS01895	COG0583	DNA-binding transcription factor activity
PCN061_RS01905	COG1662	PFAM IS1 transposase
PCN061_RS01910	COG0666	response to abiotic stimulus
PCN061_RS01935	COG1280	lysine exporter protein (LysE YggA)
PCN061_RS01945	COG3829	transcription factor binding
PCN061_RS01950	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PCN061_RS01955	COG0372	Belongs to the citrate synthase family
PCN061_RS01960	COG2079	MmgE PrpD family protein
PCN061_RS01965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PCN061_RS01970	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PCN061_RS01975	COG0402	S-adenosylhomocysteine deaminase activity
PCN061_RS01980	COG0583	DNA-binding transcription factor activity
PCN061_RS01985	COG0288	reversible hydration of carbon dioxide
PCN061_RS01995	COG2807	transmembrane transport
PCN061_RS02000	COG0110	maltose O-acetyltransferase activity
PCN061_RS02005	COG2223	nitrite transmembrane transporter activity
PCN061_RS02015	COG1609	Transcriptional regulator
PCN061_RS02020	COG1414	Transcriptional regulator
PCN061_RS02055	COG2814	Major facilitator Superfamily
PCN061_RS02060	COG3122	Protein conserved in bacteria
PCN061_RS02090	COG1215	transferase activity, transferring glycosyl groups
PCN061_RS02095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PCN061_RS02100	COG4521	taurine ABC transporter
PCN061_RS02105	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PCN061_RS02110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PCN061_RS02115	COG2175	clavaminate synthase activity
PCN061_RS02120	COG0113	porphobilinogen synthase activity
PCN061_RS02145	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS02150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCN061_RS02155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PCN061_RS02165	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
PCN061_RS02185	COG1181	Belongs to the D-alanine--D-alanine ligase family
PCN061_RS02200	COG1785	Belongs to the alkaline phosphatase family
PCN061_RS02210	COG3706	GGDEF domain
PCN061_RS02215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PCN061_RS02240	COG4126	flavin adenine dinucleotide binding
PCN061_RS02260	COG1940	carbohydrate kinase activity
PCN061_RS02265	COG2814	Major facilitator Superfamily
PCN061_RS02270	COG0419	ATPase involved in DNA repair
PCN061_RS02275	COG0420	3'-5' exonuclease activity
PCN061_RS02280	COG0745	RESPONSE REGULATOR receiver
PCN061_RS02285	COG5002	protein histidine kinase activity
PCN061_RS02290	COG1114	Component of the transport system for branched-chain amino acids
PCN061_RS02295	COG1113	amino acid transport
PCN061_RS02300	COG0366	Alpha amylase catalytic
PCN061_RS02320	COG1862	Preprotein translocase
PCN061_RS02325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PCN061_RS02330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PCN061_RS02335	COG1403	HNH endonuclease
PCN061_RS02345	COG3248	Nucleoside-binding outer membrane protein
PCN061_RS02350	COG4238	major outer membrane lipoprotein
PCN061_RS02360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PCN061_RS02360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PCN061_RS02375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PCN061_RS02380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PCN061_RS02385	COG0667	Aldo Keto reductase
PCN061_RS02395	COG0142	geranyltranstransferase activity
PCN061_RS02410	COG0693	protein deglycase activity
PCN061_RS02415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PCN061_RS02425	COG2814	Major facilitator Superfamily
PCN061_RS02435	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PCN061_RS02440	COG1845	cytochrome c oxidase, subunit III
PCN061_RS02445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PCN061_RS02450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PCN061_RS02455	COG2223	nitrite transmembrane transporter activity
PCN061_RS02460	COG3056	Lipoprotein
PCN061_RS02465	COG0271	Belongs to the BolA IbaG family
PCN061_RS02490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PCN061_RS02495	COG0776	regulation of translation
PCN061_RS02500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PCN061_RS02505	COG1555	photosystem II stabilization
PCN061_RS02510	COG0824	Thioesterase
PCN061_RS02520	COG4533	DNA binding
PCN061_RS02530	COG1522	sequence-specific DNA binding
PCN061_RS02535	COG1132	(ABC) transporter
PCN061_RS02540	COG1132	(ABC) transporter
PCN061_RS02545	COG0347	Belongs to the P(II) protein family
PCN061_RS02550	COG0004	ammonium transporteR
PCN061_RS02555	COG1946	Acyl-CoA thioesterase
PCN061_RS02560	COG3126	Type III secretion system lipoprotein chaperone (YscW)
PCN061_RS02565	COG3695	enzyme binding
PCN061_RS02570	COG5507	3-demethylubiquinone-9 3-methyltransferase
PCN061_RS02575	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PCN061_RS02590	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PCN061_RS02600	COG0110	maltose O-acetyltransferase activity
PCN061_RS02615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PCN061_RS02620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCN061_RS02625	COG1309	transcriptional regulator
PCN061_RS02630	COG3264	Mechanosensitive ion channel
PCN061_RS02630	COG1196	nuclear chromosome segregation
PCN061_RS02645	COG3923	Primosomal replication protein n
PCN061_RS02650	COG2832	Protein of unknown function (DUF454)
PCN061_RS02660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PCN061_RS02695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS02700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PCN061_RS02700	COG4651	solute:proton antiporter activity
PCN061_RS02705	COG2223	nitrite transmembrane transporter activity
PCN061_RS02710	COG0737	Belongs to the 5'-nucleotidase family
PCN061_RS02715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PCN061_RS02720	COG3735	TraB family
PCN061_RS02725	COG3093	addiction module antidote protein HigA
PCN061_RS02730	COG2217	Heavy metal translocating P-type atpase
PCN061_RS02740	COG0531	amino acid
PCN061_RS02745	COG0789	Transcriptional regulator
PCN061_RS02750	COG1585	Membrane protein implicated in regulation of membrane protease activity
PCN061_RS02755	COG0330	HflC and HflK could
PCN061_RS02760	COG4619	ABC transporter
PCN061_RS02765	COG0390	transport system, permease component
PCN061_RS02770	COG3118	belongs to the thioredoxin family
PCN061_RS02775	COG0300	oxidoreductase activity
PCN061_RS02780	COG2755	lipolytic protein G-D-S-L family
PCN061_RS02785	COG4181	ATPase activity
PCN061_RS02790	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PCN061_RS02800	COG0583	DNA-binding transcription factor activity
PCN061_RS02810	COG1414	Transcriptional regulator
PCN061_RS02815	COG3960	tartronate-semialdehyde synthase activity
PCN061_RS02820	COG3622	Belongs to the hyi family
PCN061_RS02825	COG2084	Dehydrogenase
PCN061_RS02830	COG1953	Uracil, thiamine, allantoin
PCN061_RS02840	COG2233	PERMEase
PCN061_RS02845	COG1929	Belongs to the glycerate kinase type-1 family
PCN061_RS02850	COG3257	ureidoglycine aminohydrolase activity
PCN061_RS02860	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PCN061_RS02865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PCN061_RS02870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PCN061_RS02880	COG0549	Belongs to the carbamate kinase family
PCN061_RS02885	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PCN061_RS02890	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PCN061_RS02900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PCN061_RS02910	COG1988	membrane-bound metal-dependent
PCN061_RS02915	COG2501	S4 domain
PCN061_RS02925	COG3539	Fimbrial protein
PCN061_RS02930	COG3121	Chaperone
PCN061_RS02935	COG3188	usher protein
PCN061_RS02940	COG3539	Fimbrial protein
PCN061_RS02945	COG3539	Fimbrial protein
PCN061_RS02950	COG2197	response regulator
PCN061_RS02995	COG5002	protein histidine kinase activity
PCN061_RS03000	COG0745	RESPONSE REGULATOR receiver
PCN061_RS03005	COG1538	Outer membrane efflux protein
PCN061_RS03010	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCN061_RS03015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCN061_RS03020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PCN061_RS03025	COG1113	amino acid transport
PCN061_RS03030	COG0668	transmembrane transport
PCN061_RS03035	COG0778	Nitroreductase
PCN061_RS03040	COG2315	Protein conserved in bacteria
PCN061_RS03060	COG2963	transposase activity
PCN061_RS03065	COG2801	Transposase and inactivated derivatives
PCN061_RS03075	COG3385	transposase activity
PCN061_RS03080	COG2977	Belongs to the P-Pant transferase superfamily
PCN061_RS03085	COG4771	TonB-dependent receptor
PCN061_RS03090	COG2382	esterase
PCN061_RS03095	COG3251	PFAM MbtH domain protein
PCN061_RS03100	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
PCN061_RS03100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PCN061_RS03105	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
PCN061_RS03110	COG1120	ATPase activity
PCN061_RS03115	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCN061_RS03120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCN061_RS03130	COG4592	Periplasmic binding protein
PCN061_RS03135	COG1169	isochorismate synthase
PCN061_RS03140	COG1021	2,3-dihydroxybenzoate-AMP ligase
PCN061_RS03145	COG1535	isochorismatase
PCN061_RS03145	COG3433	isochorismatase activity
PCN061_RS03150	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS03155	COG2050	protein possibly involved in aromatic compounds catabolism
PCN061_RS03160	COG1966	Carbon starvation protein
PCN061_RS03165	COG2879	small protein
PCN061_RS03170	COG0371	Dehydrogenase
PCN061_RS03175	COG0436	Aminotransferase
PCN061_RS03180	COG1475	DNA binding
PCN061_RS03185	COG3969	phosphoadenosine phosphosulfate
PCN061_RS03190	COG0583	DNA-binding transcription factor activity
PCN061_RS03195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PCN061_RS03200	COG0450	alkyl hydroperoxide reductase
PCN061_RS03205	COG3634	alkyl hydroperoxide reductase activity
PCN061_RS03210	COG0589	response to stress
PCN061_RS03215	COG1063	alcohol dehydrogenase
PCN061_RS03225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PCN061_RS03230	COG3719	Belongs to the RNase T2 family
PCN061_RS03235	COG0471	metal ion transport
PCN061_RS03250	COG3051	citrate lyase alpha subunit
PCN061_RS03255	COG2301	Belongs to the HpcH HpaI aldolase family
PCN061_RS03265	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PCN061_RS03270	COG3290	protein histidine kinase activity
PCN061_RS03275	COG4565	transcriptional regulatory protein
PCN061_RS03280	COG3069	C4-dicarboxylate transmembrane transporter activity
PCN061_RS03300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PCN061_RS03305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PCN061_RS03315	COG0583	DNA-binding transcription factor activity
PCN061_RS03335	COG1686	Belongs to the peptidase S11 family
PCN061_RS03340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PCN061_RS03345	COG0772	Belongs to the SEDS family
PCN061_RS03350	COG0768	penicillin binding
PCN061_RS03360	COG0799	negative regulation of ribosome biogenesis
PCN061_RS03365	COG0406	alpha-ribazole phosphatase activity
PCN061_RS03375	COG1466	dna polymerase III delta subunit
PCN061_RS03390	COG2888	peptidyl-tyrosine sulfation
PCN061_RS03400	COG1126	abc transporter atp-binding protein
PCN061_RS03405	COG0765	amino acid transport
PCN061_RS03410	COG0765	amino acid transport
PCN061_RS03415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCN061_RS03425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PCN061_RS03430	COG4535	Mg2 and Co2 transporter CorC
PCN061_RS03440	COG1702	phosphate starvation-inducible protein PhoH
PCN061_RS03450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PCN061_RS03490	COG0367	asparagine synthase
PCN061_RS03495	COG0647	UMP catabolic process
PCN061_RS03500	COG1846	Transcriptional regulator
PCN061_RS03500	COG1940	carbohydrate kinase activity
PCN061_RS03505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PCN061_RS03515	COG1263	PTS System
PCN061_RS03515	COG2190	(PTS) system
PCN061_RS03515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS03545	COG0735	belongs to the Fur family
PCN061_RS03560	COG0716	FMN binding
PCN061_RS03570	COG0596	Alpha beta hydrolase
PCN061_RS03575	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PCN061_RS03580	COG0033	Phosphoglucomutase
PCN061_RS03600	COG0531	amino acid
PCN061_RS03605	COG1982	Orn Lys Arg decarboxylase major
PCN061_RS03615	COG0745	RESPONSE REGULATOR receiver
PCN061_RS03620	COG2205	protein histidine kinase activity
PCN061_RS03650	COG3209	COG3209 Rhs family protein
PCN061_RS03660	COG3209	COG3209 Rhs family protein
PCN061_RS03675	COG5433	transposase activity
PCN061_RS03680	COG3272	Protein of unknown function (DUF1722)
PCN061_RS03685	COG0415	Belongs to the DNA photolyase family
PCN061_RS03690	COG3104	oligopeptide transport
PCN061_RS03695	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PCN061_RS03700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PCN061_RS03705	COG1984	allophanate hydrolase subunit 2
PCN061_RS03720	COG3180	Ammonia monooxygenase
PCN061_RS03725	COG3539	Fimbrial protein
PCN061_RS03730	COG3121	Chaperone
PCN061_RS03740	COG3539	Fimbrial protein
PCN061_RS03750	COG3539	Fimbrial protein
PCN061_RS03755	COG0372	Belongs to the citrate synthase family
PCN061_RS03765	COG2009	succinate dehydrogenase
PCN061_RS03770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PCN061_RS03775	COG1053	succinate dehydrogenase
PCN061_RS03780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PCN061_RS03790	COG0567	Dehydrogenase, E1 component
PCN061_RS03795	COG0508	dehydrogenase complex catalyzes the overall conversion of
PCN061_RS03805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PCN061_RS03810	COG2188	Transcriptional regulator
PCN061_RS03815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCN061_RS03815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS03815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCN061_RS03820	COG0383	alpha-mannosidase activity
PCN061_RS03830	COG0383	alpha-mannosidase activity
PCN061_RS03840	COG1271	oxidase subunit
PCN061_RS03845	COG1294	oxidase, subunit
PCN061_RS03850	COG4890	Cyd operon protein YbgT
PCN061_RS03855	COG3790	cyd operon protein YbgE
PCN061_RS03860	COG0824	Thioesterase
PCN061_RS03865	COG0811	peptide transport
PCN061_RS03870	COG0848	biopolymer transport protein
PCN061_RS03875	COG3064	Membrane
PCN061_RS03885	COG2885	chlorophyll binding
PCN061_RS03890	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PCN061_RS03935	COG3201	nicotinamide mononucleotide transporter
PCN061_RS03940	COG1230	cation diffusion facilitator family transporter
PCN061_RS03955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PCN061_RS03965	COG2017	converts alpha-aldose to the beta-anomer
PCN061_RS03975	COG1085	galactose-1-phosphate uridylyltransferase
PCN061_RS03980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PCN061_RS03985	COG1119	ATPase activity
PCN061_RS03990	COG3585	molybdate ion transport
PCN061_RS03990	COG2005	Transcriptional regulator
PCN061_RS04000	COG0725	ABC transporter, periplasmic molybdate-binding protein
PCN061_RS04005	COG4149	molybdate abc transporter
PCN061_RS04010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PCN061_RS04015	COG0561	phosphatase activity
PCN061_RS04025	COG0583	DNA-binding transcription factor activity
PCN061_RS04030	COG2828	Protein conserved in bacteria
PCN061_RS04045	COG0471	metal ion transport
PCN061_RS04050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PCN061_RS04055	COG4677	pectinesterase activity
PCN061_RS04060	COG1881	PFAM PEBP family protein
PCN061_RS04065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PCN061_RS04080	COG2226	methyltransferase
PCN061_RS04085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PCN061_RS04095	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PCN061_RS04110	COG0521	Mo-molybdopterin cofactor biosynthetic process
PCN061_RS04120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PCN061_RS04125	COG0314	molybdopterin synthase activity
PCN061_RS04130	COG0670	Belongs to the BI1 family
PCN061_RS04135	COG0670	Belongs to the BI1 family
PCN061_RS04140	COG0392	lysyltransferase activity
PCN061_RS04145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCN061_RS04150	COG3568	Endonuclease Exonuclease Phosphatase
PCN061_RS04160	COG0842	Transport permease protein
PCN061_RS04165	COG0842	Transport permease protein
PCN061_RS04170	COG1131	(ABC) transporter
PCN061_RS04180	COG1309	transcriptional regulator
PCN061_RS04185	COG0513	Belongs to the DEAD box helicase family
PCN061_RS04190	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
PCN061_RS04195	COG1199	ATP-dependent helicase activity
PCN061_RS04200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PCN061_RS04205	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PCN061_RS04215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PCN061_RS04225	COG4774	siderophore transport
PCN061_RS04240	COG0668	transmembrane transport
PCN061_RS04245	COG1126	abc transporter atp-binding protein
PCN061_RS04250	COG0765	amino acid transport
PCN061_RS04255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCN061_RS04270	COG5006	permease, DMT superfamily
PCN061_RS04275	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PCN061_RS04280	COG2194	sulfuric ester hydrolase activity
PCN061_RS04290	COG1321	iron dependent repressor
PCN061_RS04295	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PCN061_RS04300	COG1376	ErfK ybiS ycfS ynhG family protein
PCN061_RS04305	COG0488	(ABC) transporter
PCN061_RS04315	COG0561	phosphatase activity
PCN061_RS04320	COG1882	Formate acetyltransferase
PCN061_RS04325	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCN061_RS04330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PCN061_RS04335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PCN061_RS04340	COG0303	'Molybdopterin
PCN061_RS04345	COG1446	asparaginase
PCN061_RS04355	COG0747	negative chemotaxis
PCN061_RS04370	COG2200	EAL domain
PCN061_RS04375	COG2199	diguanylate cyclase activity
PCN061_RS04400	COG2133	pyrroloquinoline quinone binding
PCN061_RS04405	COG0625	glutathione transferase activity
PCN061_RS04410	COG1686	Belongs to the peptidase S11 family
PCN061_RS04415	COG1349	DNA-binding transcription factor activity
PCN061_RS04420	COG0671	phosphoesterase, PA-phosphatase related
PCN061_RS04425	COG2814	Major facilitator Superfamily
PCN061_RS04435	COG0561	phosphatase activity
PCN061_RS04440	COG0738	Major facilitator superfamily
PCN061_RS04445	COG3226	Transcriptional regulator
PCN061_RS04460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PCN061_RS04490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PCN061_RS04495	COG3842	ATPase activity
PCN061_RS04500	COG1176	ABC-type spermidine putrescine transport system, permease component I
PCN061_RS04505	COG1177	transmembrane transport
PCN061_RS04520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCN061_RS04525	COG4160	amino acid transport
PCN061_RS04530	COG4215	(ABC) transporter
PCN061_RS04535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCN061_RS04540	COG1126	abc transporter atp-binding protein
PCN061_RS04555	COG3023	N-Acetylmuramoyl-L-alanine amidase
PCN061_RS04560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PCN061_RS04565	COG0702	epimerase
PCN061_RS04570	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PCN061_RS04575	COG0028	Belongs to the TPP enzyme family
PCN061_RS04580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PCN061_RS04590	COG2431	L-lysine efflux transmembrane transporter activity
PCN061_RS04605	COG3593	DNA synthesis involved in DNA repair
PCN061_RS04610	COG2990	Protein conserved in bacteria
PCN061_RS04615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCN061_RS04620	COG0577	efflux transmembrane transporter activity
PCN061_RS04620	COG1136	(ABC) transporter
PCN061_RS04625	COG1278	Cold shock
PCN061_RS04635	COG0542	response to heat
PCN061_RS04655	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PCN061_RS04665	COG0492	ferredoxin-NADP+ reductase activity
PCN061_RS04670	COG1522	sequence-specific DNA binding
PCN061_RS04675	COG1674	ftsk spoiiie
PCN061_RS04675	COG1178	ABC-type Fe3 transport system permease component
PCN061_RS04685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PCN061_RS04695	COG0243	molybdopterin cofactor binding
PCN061_RS04700	COG0437	4 iron, 4 sulfur cluster binding
PCN061_RS04705	COG3302	dmso reductase anchor subunit
PCN061_RS04710	COG1335	isochorismatase
PCN061_RS04720	COG0531	amino acid
PCN061_RS04725	COG0583	DNA-binding transcription factor activity
PCN061_RS04735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCN061_RS04740	COG1882	Formate acetyltransferase
PCN061_RS04745	COG2116	formate transmembrane transporter activity
PCN061_RS04750	COG1944	ATP diphosphatase activity
PCN061_RS04755	COG2323	membrane
PCN061_RS04770	COG0501	Belongs to the peptidase M48B family
PCN061_RS04780	COG0539	negative regulation of cytoplasmic translation
PCN061_RS04790	COG2333	competence protein COMEC
PCN061_RS04790	COG0658	competence protein
PCN061_RS04795	COG1132	(ABC) transporter
PCN061_RS04805	COG3214	Protein conserved in bacteria
PCN061_RS04820	COG3173	Aminoglycoside phosphotransferase
PCN061_RS04825	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PCN061_RS04830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PCN061_RS04840	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
PCN061_RS04850	COG2989	Protein conserved in bacteria
PCN061_RS04855	COG3108	Peptidase M15
PCN061_RS04860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PCN061_RS04865	COG1448	Aminotransferase
PCN061_RS04890	COG0308	aminopeptidase N
PCN061_RS04895	COG1116	anion transmembrane transporter activity
PCN061_RS04900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PCN061_RS04910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PCN061_RS04915	COG0431	NADPH-dependent FMN reductase
PCN061_RS04925	COG3121	Chaperone
PCN061_RS04930	COG3188	usher protein
PCN061_RS04935	COG3539	Fimbrial protein
PCN061_RS04940	COG3539	Fimbrial protein
PCN061_RS04945	COG3539	Fimbrial protein
PCN061_RS04950	COG3121	Chaperone
PCN061_RS04965	COG0633	Ferredoxin
PCN061_RS04965	COG3217	Mosc domain protein beta barrel domain protein
PCN061_RS04975	COG0488	(ABC) transporter
PCN061_RS04980	COG2995	paraquat-inducible protein a
PCN061_RS04985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PCN061_RS04985	COG3008	intermembrane lipid transfer
PCN061_RS04990	COG3009	Protein conserved in bacteria
PCN061_RS04995	COG3130	regulation of translation
PCN061_RS05005	COG1067	ATP-dependent peptidase activity
PCN061_RS05015	COG2885	chlorophyll binding
PCN061_RS05015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PCN061_RS05030	COG3070	regulator of competence-specific genes
PCN061_RS05035	COG1289	transmembrane transporter activity
PCN061_RS05040	COG3304	Inner membrane component domain
PCN061_RS05045	COG0210	DNA helicase
PCN061_RS05065	COG1832	CoA-binding protein
PCN061_RS05080	COG1254	Belongs to the acylphosphatase family
PCN061_RS05085	COG2920	part of a sulfur-relay system
PCN061_RS05090	COG0670	Belongs to the BI1 family
PCN061_RS05100	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
PCN061_RS05105	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
PCN061_RS05110	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
PCN061_RS05115	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PCN061_RS05120	COG1999	signal sequence binding
PCN061_RS05125	COG1773	rubredoxin
PCN061_RS05130	COG1271	oxidase subunit
PCN061_RS05135	COG1294	oxidase, subunit
PCN061_RS05150	COG0489	protein tyrosine kinase activity
PCN061_RS05150	COG3206	protein involved in exopolysaccharide biosynthesis
PCN061_RS05160	COG0489	protein tyrosine kinase activity
PCN061_RS05160	COG3206	protein involved in exopolysaccharide biosynthesis
PCN061_RS05165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PCN061_RS05170	COG1596	polysaccharide export
PCN061_RS05175	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PCN061_RS05195	COG1278	Cold shock
PCN061_RS05200	COG1278	Cold shock
PCN061_RS05215	COG0348	domain, Protein
PCN061_RS05220	COG0784	Response regulator, receiver
PCN061_RS05220	COG2198	Histidine kinase
PCN061_RS05220	COG2205	protein histidine kinase activity
PCN061_RS05225	COG1879	ABC-type sugar transport system periplasmic component
PCN061_RS05230	COG0745	RESPONSE REGULATOR receiver
PCN061_RS05235	COG3005	denitrification pathway
PCN061_RS05240	COG0243	molybdopterin cofactor binding
PCN061_RS05285	COG3729	General stress protein
PCN061_RS05290	COG2233	PERMEase
PCN061_RS05325	COG1309	transcriptional regulator
PCN061_RS05330	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PCN061_RS05330	COG0506	proline dehydrogenase activity
PCN061_RS05330	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PCN061_RS05340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PCN061_RS05355	COG2822	iron ion transport
PCN061_RS05360	COG2837	iron assimilation
PCN061_RS05370	COG1702	phosphate starvation-inducible protein PhoH
PCN061_RS05375	COG3658	cytochrome
PCN061_RS05380	COG1215	transferase activity, transferring glycosyl groups
PCN061_RS05385	COG1649	PFAM Uncharacterised BCR, COG1649
PCN061_RS05385	COG0726	polysaccharide deacetylase
PCN061_RS05390	COG0457	Tetratricopeptide repeat
PCN061_RS05395	COG3706	GGDEF domain
PCN061_RS05400	COG2801	Transposase and inactivated derivatives
PCN061_RS05440	COG3381	protein complex oligomerization
PCN061_RS05450	COG1462	curli production assembly transport component CsgG
PCN061_RS05465	COG2197	response regulator
PCN061_RS05495	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
PCN061_RS05500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCN061_RS05525	COG2943	transferase activity, transferring hexosyl groups
PCN061_RS05530	COG5645	(Lipo)protein
PCN061_RS05550	COG1560	Kdo2-lipid A biosynthetic process
PCN061_RS05560	COG2353	YceI-like domain
PCN061_RS05565	COG3038	cytochrome b561
PCN061_RS05600	COG2999	glutathione oxidoreductase activity
PCN061_RS05610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PCN061_RS05620	COG0673	inositol 2-dehydrogenase activity
PCN061_RS05625	COG0728	peptidoglycan biosynthetic process
PCN061_RS05630	COG3418	PFAM FlgN family protein
PCN061_RS05635	COG2747	anti-sigma28 factor FlgM
PCN061_RS05640	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
PCN061_RS05645	COG1815	bacterial-type flagellum-dependent cell motility
PCN061_RS05650	COG1558	bacterial-type flagellum-dependent cell motility
PCN061_RS05655	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PCN061_RS05660	COG1749	Flagellar hook protein flgE
PCN061_RS05665	COG4787	bacterial-type flagellum-dependent cell motility
PCN061_RS05670	COG4786	Flagellar basal body rod
PCN061_RS05685	COG3951	Flagellar rod assembly protein muramidase FlgJ
PCN061_RS05685	COG1705	Flagellar rod assembly protein muramidase FlgJ
PCN061_RS05690	COG1256	bacterial-type flagellum assembly
PCN061_RS05695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PCN061_RS05700	COG1530	ribonuclease E activity
PCN061_RS05710	COG0564	pseudouridine synthase activity
PCN061_RS05715	COG0424	maF-like protein
PCN061_RS05720	COG1399	metal-binding, possibly nucleic acid-binding protein
PCN061_RS05740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PCN061_RS05745	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS05755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PCN061_RS05760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PCN061_RS05765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PCN061_RS05775	COG0470	DNA polymerase III
PCN061_RS05780	COG0084	hydrolase, TatD family'
PCN061_RS05785	COG1263	PTS System
PCN061_RS05785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS05790	COG4773	Receptor
PCN061_RS05795	COG0537	adenosine 5'-monophosphoramidase activity
PCN061_RS05800	COG5633	Lipoprotein
PCN061_RS05805	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
PCN061_RS05825	COG1252	NADH dehydrogenase
PCN061_RS05830	COG3134	Outer membrane lipoprotein
PCN061_RS05835	COG1309	transcriptional regulator
PCN061_RS05845	COG1376	ErfK ybiS ycfS ynhG family protein
PCN061_RS05845	COG1388	LysM domain
PCN061_RS05850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PCN061_RS05855	COG4763	Acyl-transferase
PCN061_RS05860	COG4591	ABC-type transport system involved in lipoprotein release permease component
PCN061_RS05865	COG1136	(ABC) transporter
PCN061_RS05870	COG4591	ABC-type transport system involved in lipoprotein release permease component
PCN061_RS05880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PCN061_RS05885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PCN061_RS05890	COG1177	transmembrane transport
PCN061_RS05915	COG2850	peptidyl-arginine hydroxylation
PCN061_RS05920	COG2205	protein histidine kinase activity
PCN061_RS05925	COG0745	RESPONSE REGULATOR receiver
PCN061_RS05930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PCN061_RS05950	COG1187	pseudouridine synthase activity
PCN061_RS05955	COG0538	isocitrate dehydrogenase activity
PCN061_RS05970	COG5562	phage envelope protein
PCN061_RS05975	COG0789	Transcriptional regulator
PCN061_RS05980	COG2200	EAL domain
PCN061_RS06005	COG2200	EAL domain
PCN061_RS06055	COG2894	cell division
PCN061_RS06080	COG0179	Fumarylacetoacetate (FAA) hydrolase
PCN061_RS06100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PCN061_RS06105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PCN061_RS06110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PCN061_RS06125	COG2719	SpoVR family
PCN061_RS06135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PCN061_RS06145	COG1619	proteins homologs of microcin C7 resistance protein MccF
PCN061_RS06155	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PCN061_RS06175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCN061_RS06175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS06175	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
PCN061_RS06180	COG1461	Dihydroxyacetone kinase
PCN061_RS06185	COG2376	Dihydroxyacetone kinase
PCN061_RS06190	COG3284	Transcriptional regulator
PCN061_RS06195	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS06205	COG0012	GTP binding
PCN061_RS06220	COG0659	secondary active sulfate transmembrane transporter activity
PCN061_RS06225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PCN061_RS06250	COG2890	protein-(glutamine-N5) methyltransferase activity
PCN061_RS06255	COG3094	Invasion gene expression up-regulator, SirB
PCN061_RS06260	COG2912	Transglutaminase-like superfamily
PCN061_RS06285	COG0387	Pfam Sodium calcium exchanger
PCN061_RS06290	COG4572	Cation transport regulator
PCN061_RS06295	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
PCN061_RS06300	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PCN061_RS06305	COG4932	domain protein
PCN061_RS06310	COG2197	response regulator
PCN061_RS06315	COG3850	Histidine kinase
PCN061_RS06325	COG2223	nitrite transmembrane transporter activity
PCN061_RS06330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PCN061_RS06335	COG1140	nitrate reductase beta subunit
PCN061_RS06340	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PCN061_RS06345	COG2181	nitrate reductase activity
PCN061_RS06365	COG0788	formyltetrahydrofolate deformylase activity
PCN061_RS06375	COG1752	Esterase of the alpha-beta hydrolase superfamily
PCN061_RS06380	COG0745	RESPONSE REGULATOR receiver
PCN061_RS06385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PCN061_RS06395	COG1435	thymidine kinase activity
PCN061_RS06410	COG1012	belongs to the aldehyde dehydrogenase family
PCN061_RS06410	COG1454	alcohol dehydrogenase
PCN061_RS06415	COG2095	MarC family integral membrane protein
PCN061_RS06420	COG4166	transmembrane transport
PCN061_RS06425	COG0601	transmembrane transport
PCN061_RS06430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCN061_RS06435	COG0444	Belongs to the ABC transporter superfamily
PCN061_RS06440	COG4608	Belongs to the ABC transporter superfamily
PCN061_RS06460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PCN061_RS06465	COG2350	Protein conserved in bacteria
PCN061_RS06470	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PCN061_RS06475	COG1607	acyl-coa hydrolase
PCN061_RS06490	COG3047	cAMP biosynthetic process
PCN061_RS06495	COG3685	Protein conserved in bacteria
PCN061_RS06500	COG3685	Protein conserved in bacteria
PCN061_RS06505	COG3729	General stress protein
PCN061_RS06520	COG0134	indole-3-glycerol-phosphate synthase activity
PCN061_RS06520	COG0135	phosphoribosylanthranilate isomerase activity
PCN061_RS06525	COG0512	Glutamine amidotransferase of anthranilate synthase
PCN061_RS06525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PCN061_RS06530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PCN061_RS06535	COG0613	PHP domain protein
PCN061_RS06540	COG0009	L-threonylcarbamoyladenylate synthase
PCN061_RS06545	COG4907	membrane protein (DUF2207)
PCN061_RS06550	COG1187	pseudouridine synthase activity
PCN061_RS06555	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
PCN061_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS06570	COG0616	signal peptide processing
PCN061_RS06585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PCN061_RS06590	COG0583	DNA-binding transcription factor activity
PCN061_RS06615	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PCN061_RS06625	COG0671	phosphoesterase, PA-phosphatase related
PCN061_RS06630	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
PCN061_RS06635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PCN061_RS06645	COG0023	Translation Initiation Factor
PCN061_RS06655	COG1349	DNA-binding transcription factor activity
PCN061_RS06665	COG5001	Diguanylate cyclase
PCN061_RS06680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PCN061_RS06680	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PCN061_RS06685	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PCN061_RS06690	COG2852	Protein conserved in bacteria
PCN061_RS06695	COG4172	Belongs to the ABC transporter superfamily
PCN061_RS06700	COG4172	Belongs to the ABC transporter superfamily
PCN061_RS06705	COG4171	peptide transport system, permease
PCN061_RS06710	COG4168	peptide transport system, permease
PCN061_RS06715	COG4166	transmembrane transport
PCN061_RS06730	COG0531	amino acid
PCN061_RS06735	COG0174	glutamine synthetase
PCN061_RS06740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PCN061_RS06745	COG1396	sequence-specific DNA binding
PCN061_RS06745	COG1917	Cupin 2, conserved barrel domain protein
PCN061_RS06750	COG1012	belongs to the aldehyde dehydrogenase family
PCN061_RS06755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PCN061_RS06760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PCN061_RS06765	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PCN061_RS06770	COG1842	Phage shock protein A
PCN061_RS06780	COG1983	PspC domain protein
PCN061_RS06790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCN061_RS06805	COG1653	transport
PCN061_RS06810	COG1175	transmembrane transport
PCN061_RS06815	COG0395	ABC-type sugar transport system, permease component
PCN061_RS06820	COG1063	alcohol dehydrogenase
PCN061_RS06825	COG1082	Xylose isomerase domain protein TIM barrel
PCN061_RS06830	COG0673	inositol 2-dehydrogenase activity
PCN061_RS06835	COG1554	hydrolase, family 65, central catalytic
PCN061_RS06840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PCN061_RS06845	COG3842	ATPase activity
PCN061_RS06855	COG1609	Transcriptional regulator
PCN061_RS06860	COG3106	COG3106 Predicted ATPase
PCN061_RS06870	COG3283	Transcriptional regulator of aromatic amino acids metabolism
PCN061_RS06875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PCN061_RS06880	COG4948	Mandelate Racemase Muconate Lactonizing
PCN061_RS06885	COG2866	Carboxypeptidase
PCN061_RS06890	COG0702	epimerase
PCN061_RS06895	COG1073	alpha beta
PCN061_RS06900	COG0583	DNA-binding transcription factor activity
PCN061_RS06910	COG4166	transmembrane transport
PCN061_RS06915	COG0668	transmembrane transport
PCN061_RS06920	COG3182	Iron-regulated membrane protein
PCN061_RS06925	COG0589	response to stress
PCN061_RS06930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCN061_RS06935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PCN061_RS06940	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
PCN061_RS06950	COG1473	amidohydrolase
PCN061_RS06955	COG1473	amidohydrolase
PCN061_RS06960	COG0583	DNA-binding transcription factor activity
PCN061_RS06970	COG2840	Smr protein MutS2
PCN061_RS06975	COG3706	GGDEF domain
PCN061_RS06990	COG0513	Belongs to the DEAD box helicase family
PCN061_RS07000	COG0589	response to stress
PCN061_RS07005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PCN061_RS07020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PCN061_RS07025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCN061_RS07025	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PCN061_RS07025	COG1013	pyruvate-flavodoxin oxidoreductase activity
PCN061_RS07025	COG0674	pyruvate-flavodoxin oxidoreductase activity
PCN061_RS07030	COG3042	response to heat
PCN061_RS07035	COG3187	Heat shock protein
PCN061_RS07040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCN061_RS07045	COG2911	Protein conserved in bacteria
PCN061_RS07055	COG3784	Protein of unknown function (DUF1318)
PCN061_RS07065	COG2267	carboxylic ester hydrolase activity
PCN061_RS07070	COG0671	phosphoesterase, PA-phosphatase related
PCN061_RS07070	COG2453	phosphatase
PCN061_RS07080	COG1643	Atp-dependent helicase
PCN061_RS07085	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PCN061_RS07090	COG1012	belongs to the aldehyde dehydrogenase family
PCN061_RS07095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PCN061_RS07100	COG3038	cytochrome b561
PCN061_RS07115	COG2801	Transposase and inactivated derivatives
PCN061_RS07120	COG2963	transposase activity
PCN061_RS07125	COG0840	transmembrane signaling receptor activity
PCN061_RS07130	COG0583	DNA-binding transcription factor activity
PCN061_RS07135	COG5383	Protein conserved in bacteria
PCN061_RS07150	COG2841	Protein conserved in bacteria
PCN061_RS07155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PCN061_RS07160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PCN061_RS07165	COG1275	C4-dicarboxylate transporter malic acid transport protein
PCN061_RS07170	COG0500	methyltransferase
PCN061_RS07195	COG0675	Transposase, IS605 OrfB family
PCN061_RS07200	COG3135	benzoate transporter
PCN061_RS07205	COG1396	sequence-specific DNA binding
PCN061_RS07210	COG0826	peptidase U32
PCN061_RS07220	COG1724	mRNA binding
PCN061_RS07225	COG1598	PFAM Uncharacterised protein family UPF0150
PCN061_RS07230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PCN061_RS07235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PCN061_RS07240	COG3842	ATPase activity
PCN061_RS07245	COG1176	ABC-type spermidine putrescine transport system, permease component I
PCN061_RS07250	COG1177	transmembrane transport
PCN061_RS07275	COG3238	Protein conserved in bacteria
PCN061_RS07280	COG1247	-acetyltransferase
PCN061_RS07285	COG2130	NADP-dependent
PCN061_RS07290	COG1802	Transcriptional regulator
PCN061_RS07295	COG4772	TonB-dependent receptor
PCN061_RS07300	COG3391	amine dehydrogenase activity
PCN061_RS07305	COG1113	amino acid transport
PCN061_RS07310	COG0625	glutathione transferase activity
PCN061_RS07330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PCN061_RS07335	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PCN061_RS07340	COG0384	phenazine biosynthesis protein PhzF
PCN061_RS07345	COG2181	nitrate reductase activity
PCN061_RS07350	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PCN061_RS07355	COG1140	nitrate reductase beta subunit
PCN061_RS07360	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PCN061_RS07365	COG2223	nitrite transmembrane transporter activity
PCN061_RS07370	COG4886	Leucine-rich repeat (LRR) protein
PCN061_RS07375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PCN061_RS07380	COG0697	spore germination
PCN061_RS07385	COG3383	formate dehydrogenase (NAD+) activity
PCN061_RS07385	COG0243	molybdopterin cofactor binding
PCN061_RS07390	COG3383	formate dehydrogenase (NAD+) activity
PCN061_RS07390	COG0243	molybdopterin cofactor binding
PCN061_RS07395	COG0437	4 iron, 4 sulfur cluster binding
PCN061_RS07400	COG2864	formate dehydrogenase
PCN061_RS07405	COG3093	addiction module antidote protein HigA
PCN061_RS07410	COG1064	alcohol dehydrogenase
PCN061_RS07430	COG1764	response to oxidative stress
PCN061_RS07435	COG4608	Belongs to the ABC transporter superfamily
PCN061_RS07440	COG0444	Belongs to the ABC transporter superfamily
PCN061_RS07445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCN061_RS07450	COG0601	transmembrane transport
PCN061_RS07455	COG0747	negative chemotaxis
PCN061_RS07460	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PCN061_RS07465	COG2202	Pas domain
PCN061_RS07465	COG2200	EAL domain
PCN061_RS07465	COG2199	diguanylate cyclase activity
PCN061_RS07470	COG3706	GGDEF domain
PCN061_RS07475	COG1649	PFAM Uncharacterised BCR, COG1649
PCN061_RS07480	COG0531	amino acid
PCN061_RS07485	COG0076	glutamate decarboxylase activity
PCN061_RS07495	COG0612	Peptidase, M16
PCN061_RS07500	COG4771	TonB-dependent receptor
PCN061_RS07505	COG4178	(ABC) transporter
PCN061_RS07510	COG0641	radical SAM
PCN061_RS07515	COG3119	arylsulfatase activity
PCN061_RS07520	COG2207	Transcriptional regulator
PCN061_RS07530	COG0243	molybdopterin cofactor binding
PCN061_RS07535	COG3539	Fimbrial protein
PCN061_RS07540	COG3539	Fimbrial protein
PCN061_RS07545	COG3539	Fimbrial protein
PCN061_RS07550	COG3188	usher protein
PCN061_RS07555	COG4977	sequence-specific DNA binding
PCN061_RS07575	COG3550	peptidyl-serine autophosphorylation
PCN061_RS07580	COG1396	sequence-specific DNA binding
PCN061_RS07590	COG3210	domain, Protein
PCN061_RS07590	COG2911	Protein conserved in bacteria
PCN061_RS07600	COG2801	Transposase and inactivated derivatives
PCN061_RS07605	COG3210	domain, Protein
PCN061_RS07605	COG2911	Protein conserved in bacteria
PCN061_RS07655	COG3781	membrane
PCN061_RS07665	COG2199	diguanylate cyclase activity
PCN061_RS07675	COG2066	Belongs to the glutaminase family
PCN061_RS07680	COG1012	belongs to the aldehyde dehydrogenase family
PCN061_RS07685	COG0583	DNA-binding transcription factor activity
PCN061_RS07700	COG2801	Transposase and inactivated derivatives
PCN061_RS07720	COG1846	Transcriptional regulator
PCN061_RS07725	COG4977	sequence-specific DNA binding
PCN061_RS07735	COG2723	6-phospho-beta-galactosidase activity
PCN061_RS07745	COG1447	Phosphotransferase system cellobiose-specific component IIA
PCN061_RS07750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCN061_RS07760	COG2188	Transcriptional regulator
PCN061_RS07765	COG0697	spore germination
PCN061_RS07770	COG2814	Major facilitator Superfamily
PCN061_RS07780	COG3706	GGDEF domain
PCN061_RS07785	COG3111	PFAM Bacterial OB fold (BOF) protein
PCN061_RS07790	COG1546	Belongs to the CinA family
PCN061_RS07795	COG0339	signal peptide processing
PCN061_RS07800	COG4221	oxidoreductase activity
PCN061_RS07805	COG1802	Transcriptional regulator
PCN061_RS07820	COG0477	Major facilitator Superfamily
PCN061_RS07835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PCN061_RS07930	COG0740	serine-type endopeptidase activity
PCN061_RS07955	COG3436	PFAM IS66 Orf2 family protein
PCN061_RS07960	COG4372	Transposase
PCN061_RS07995	COG1278	Cold shock
PCN061_RS08005	COG3772	lysozyme
PCN061_RS08020	COG2207	Transcriptional regulator
PCN061_RS08030	COG2801	Transposase and inactivated derivatives
PCN061_RS08035	COG3272	Protein of unknown function (DUF1722)
PCN061_RS08050	COG1403	HNH endonuclease
PCN061_RS08135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PCN061_RS08145	COG0582	viral genome integration into host DNA
PCN061_RS08150	COG1063	alcohol dehydrogenase
PCN061_RS08155	COG4948	Mandelate Racemase Muconate Lactonizing
PCN061_RS08170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PCN061_RS08185	COG0243	molybdopterin cofactor binding
PCN061_RS08190	COG0243	molybdopterin cofactor binding
PCN061_RS08195	COG0437	4 iron, 4 sulfur cluster binding
PCN061_RS08200	COG3302	dmso reductase anchor subunit
PCN061_RS08205	COG3381	protein complex oligomerization
PCN061_RS08215	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PCN061_RS08220	COG1940	carbohydrate kinase activity
PCN061_RS08225	COG0583	DNA-binding transcription factor activity
PCN061_RS08230	COG2814	Major facilitator Superfamily
PCN061_RS08245	COG3591	Belongs to the peptidase S1B family
PCN061_RS08260	COG0628	permease
PCN061_RS08265	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PCN061_RS08270	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PCN061_RS08280	COG0531	amino acid
PCN061_RS08290	COG3136	membrane protein required for alginate biosynthesis
PCN061_RS08295	COG0745	RESPONSE REGULATOR receiver
PCN061_RS08300	COG2205	protein histidine kinase activity
PCN061_RS08310	COG0114	fumarate hydratase activity
PCN061_RS08315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
PCN061_RS08315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
PCN061_RS08320	COG1482	cell wall glycoprotein biosynthetic process
PCN061_RS08325	COG5339	Protein conserved in bacteria
PCN061_RS08345	COG2211	Major facilitator Superfamily
PCN061_RS08350	COG1662	PFAM IS1 transposase
PCN061_RS08360	COG3250	beta-galactosidase activity
PCN061_RS08365	COG1309	transcriptional regulator
PCN061_RS08370	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS08375	COG1609	Transcriptional regulator
PCN061_RS08380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS08380	COG1263	PTS System
PCN061_RS08385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PCN061_RS08395	COG0673	inositol 2-dehydrogenase activity
PCN061_RS08435	COG4659	FMN binding
PCN061_RS08445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PCN061_RS08455	COG3104	oligopeptide transport
PCN061_RS08460	COG0625	glutathione transferase activity
PCN061_RS08465	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PCN061_RS08480	COG3895	Periplasmic Protein
PCN061_RS08490	COG3133	Outer membrane lipoprotein
PCN061_RS08505	COG1566	PFAM secretion protein HlyD family protein
PCN061_RS08510	COG1289	transmembrane transporter activity
PCN061_RS08515	COG2032	superoxide dismutase activity
PCN061_RS08520	COG4989	oxidoreductase activity
PCN061_RS08525	COG3313	Fe-S protein
PCN061_RS08530	COG1309	transcriptional regulator
PCN061_RS08535	COG1902	pentaerythritol trinitrate reductase activity
PCN061_RS08540	COG0346	lactoylglutathione lyase activity
PCN061_RS08550	COG1201	RNA secondary structure unwinding
PCN061_RS08555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PCN061_RS08560	COG0791	NLP P60 protein
PCN061_RS08565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PCN061_RS08570	COG2814	Major facilitator Superfamily
PCN061_RS08590	COG0583	DNA-binding transcription factor activity
PCN061_RS08595	COG2814	Major facilitator Superfamily
PCN061_RS08600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PCN061_RS08605	COG0307	riboflavin synthase, alpha
PCN061_RS08615	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS08635	COG4529	Protein conserved in bacteria
PCN061_RS08645	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
PCN061_RS08650	COG0437	4 iron, 4 sulfur cluster binding
PCN061_RS08660	COG2414	aldehyde ferredoxin oxidoreductase
PCN061_RS08665	COG0437	4 iron, 4 sulfur cluster binding
PCN061_RS08675	COG0469	pyruvate kinase activity
PCN061_RS08680	COG4238	major outer membrane lipoprotein
PCN061_RS08685	COG1376	ErfK ybiS ycfS ynhG family protein
PCN061_RS08700	COG0719	Fe-S assembly protein
PCN061_RS08705	COG0396	ATPase activity
PCN061_RS08710	COG0719	Fe-S assembly protein
PCN061_RS08715	COG0316	Belongs to the HesB IscA family
PCN061_RS08725	COG2050	protein possibly involved in aromatic compounds catabolism
PCN061_RS08730	COG0247	lactate metabolic process
PCN061_RS08730	COG0277	FAD linked oxidase domain protein
PCN061_RS08735	COG0628	permease
PCN061_RS08745	COG0738	Major facilitator superfamily
PCN061_RS08750	COG2271	Major facilitator Superfamily
PCN061_RS08765	COG4670	ketone body catabolic process
PCN061_RS08770	COG1960	acyl-CoA dehydrogenase activity
PCN061_RS08775	COG1917	Cupin 2, conserved barrel domain protein
PCN061_RS08775	COG2207	Transcriptional regulator
PCN061_RS08785	COG2086	electron transfer activity
PCN061_RS08790	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PCN061_RS08795	COG0644	oxidoreductase
PCN061_RS08800	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
PCN061_RS08805	COG0318	PFAM AMP-dependent synthetase and ligase
PCN061_RS08810	COG0574	Belongs to the PEP-utilizing enzyme family
PCN061_RS08810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCN061_RS08825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PCN061_RS08830	COG4256	Hemin uptake protein
PCN061_RS08845	COG0791	NLP P60 protein
PCN061_RS08855	COG0386	Belongs to the glutathione peroxidase family
PCN061_RS08870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCN061_RS08870	COG0072	phenylalanine-tRNA ligase activity
PCN061_RS08915	COG3137	Salt-induced outer membrane protein
PCN061_RS08920	COG1105	Belongs to the carbohydrate kinase PfkB family
PCN061_RS08930	COG3001	Fructosamine kinase
PCN061_RS08940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PCN061_RS08945	COG1988	membrane-bound metal-dependent
PCN061_RS08950	COG1823	symporter activity
PCN061_RS08965	COG0753	catalase activity
PCN061_RS08975	COG1486	melibiose metabolic process
PCN061_RS08980	COG2169	Transcriptional regulator
PCN061_RS08980	COG1917	Cupin 2, conserved barrel domain protein
PCN061_RS08985	COG1447	Phosphotransferase system cellobiose-specific component IIA
PCN061_RS08990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCN061_RS08995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCN061_RS09000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PCN061_RS09015	COG0322	excinuclease ABC activity
PCN061_RS09025	COG3678	ATP-independent chaperone mediated protein folding
PCN061_RS09055	COG0708	Exodeoxyribonuclease III
PCN061_RS09065	COG0398	Pfam SNARE associated Golgi protein
PCN061_RS09075	COG0398	Pfam SNARE associated Golgi protein
PCN061_RS09080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PCN061_RS09085	COG4134	Bacterial extracellular solute-binding protein
PCN061_RS09090	COG4135	transport system, permease component
PCN061_RS09095	COG4136	ATPase activity
PCN061_RS09100	COG2897	thiosulfate sulfurtransferase activity
PCN061_RS09105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PCN061_RS09110	COG0494	nUDIX hydrolase
PCN061_RS09120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PCN061_RS09130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PCN061_RS09145	COG0778	Nitroreductase
PCN061_RS09155	COG0616	signal peptide processing
PCN061_RS09160	COG0252	asparaginase activity
PCN061_RS09165	COG1335	isochorismatase
PCN061_RS09170	COG2814	Major facilitator Superfamily
PCN061_RS09175	COG1349	DNA-binding transcription factor activity
PCN061_RS09180	COG0667	Aldo Keto reductase
PCN061_RS09185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS09195	COG1063	alcohol dehydrogenase
PCN061_RS09200	COG2271	Major facilitator Superfamily
PCN061_RS09205	COG1063	alcohol dehydrogenase
PCN061_RS09210	COG3139	Protein of unknown function (DUF1315)
PCN061_RS09220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PCN061_RS09225	COG0676	glucose-6-phosphate 1-epimerase activity
PCN061_RS09230	COG0656	L-ascorbic acid biosynthetic process
PCN061_RS09235	COG3713	MltA-interacting MipA family protein
PCN061_RS09240	COG2766	serine protein kinase
PCN061_RS09250	COG2199	diguanylate cyclase activity
PCN061_RS09255	COG2199	diguanylate cyclase activity
PCN061_RS09260	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PCN061_RS09275	COG2207	Transcriptional regulator
PCN061_RS09290	COG3189	MarR family transcriptional regulator
PCN061_RS09295	COG3042	response to heat
PCN061_RS09300	COG2203	Gaf domain
PCN061_RS09300	COG2199	diguanylate cyclase activity
PCN061_RS09310	COG2261	transglycosylase associated protein
PCN061_RS09320	COG3615	Tellurite resistance protein tehB
PCN061_RS09330	COG0583	DNA-binding transcription factor activity
PCN061_RS09335	COG0473	3-isopropylmalate dehydrogenase activity
PCN061_RS09340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PCN061_RS09345	COG4638	Rieske (2fe-2S)
PCN061_RS09350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PCN061_RS09355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PCN061_RS09360	COG0318	PFAM AMP-dependent synthetase and ligase
PCN061_RS09365	COG3065	identical protein binding
PCN061_RS09370	COG1214	PFAM Peptidase M22, glycoprotease
PCN061_RS09375	COG1199	ATP-dependent helicase activity
PCN061_RS09380	COG0251	oxidation-reduction process
PCN061_RS09400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PCN061_RS09410	COG1760	l-serine dehydratase
PCN061_RS09415	COG2200	EAL domain
PCN061_RS09420	COG1253	flavin adenine dinucleotide binding
PCN061_RS09430	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS09430	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS09435	COG3715	PTS system
PCN061_RS09440	COG3716	PTS system mannose fructose sorbose family IID component
PCN061_RS09460	COG2226	methyltransferase
PCN061_RS09495	COG1414	Transcriptional regulator
PCN061_RS09500	COG2814	Major facilitator Superfamily
PCN061_RS09510	COG0793	Belongs to the peptidase S41A family
PCN061_RS09520	COG1956	GAF domain-containing protein
PCN061_RS09525	COG2995	paraquat-inducible protein a
PCN061_RS09530	COG3008	intermembrane lipid transfer
PCN061_RS09550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PCN061_RS09565	COG1276	copper resistance
PCN061_RS09570	COG2372	response to copper ion
PCN061_RS09580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PCN061_RS09585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PCN061_RS09590	COG1770	oligopeptidase
PCN061_RS09595	COG2979	Protein of unknown function (DUF533)
PCN061_RS09620	COG3141	response to X-ray
PCN061_RS09630	COG0800	Aldolase
PCN061_RS09635	COG0129	dihydroxy-acid dehydratase activity
PCN061_RS09640	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PCN061_RS09650	COG1737	Transcriptional regulator
PCN061_RS09655	COG0469	pyruvate kinase activity
PCN061_RS09660	COG1560	Kdo2-lipid A biosynthetic process
PCN061_RS09665	COG0739	heme binding
PCN061_RS09670	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PCN061_RS09680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PCN061_RS09710	COG0217	transcriptional regulatory protein
PCN061_RS09715	COG0494	nUDIX hydrolase
PCN061_RS09725	COG1335	isochorismatase
PCN061_RS09730	COG1801	Protein of unknown function DUF72
PCN061_RS09735	COG3788	relative of glutathione S-transferase, MAPEG superfamily
PCN061_RS09755	COG3005	denitrification pathway
PCN061_RS09765	COG3102	Protein conserved in bacteria
PCN061_RS09775	COG3755	Protein conserved in bacteria
PCN061_RS09790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PCN061_RS09795	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PCN061_RS09800	COG0745	RESPONSE REGULATOR receiver
PCN061_RS09810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PCN061_RS09815	COG0840	transmembrane signaling receptor activity
PCN061_RS09820	COG0840	transmembrane signaling receptor activity
PCN061_RS09825	COG0835	chemotaxis
PCN061_RS09830	COG0643	Histidine kinase
PCN061_RS09830	COG2198	Histidine kinase
PCN061_RS09835	COG1360	Flagellar Motor Protein
PCN061_RS09840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PCN061_RS09855	COG0589	response to stress
PCN061_RS09865	COG1877	trehalose-phosphatase activity
PCN061_RS09870	COG1172	Belongs to the binding-protein-dependent transport system permease family
PCN061_RS09875	COG1129	ABC transporter
PCN061_RS09880	COG1879	ABC-type sugar transport system periplasmic component
PCN061_RS09885	COG1528	Iron-storage protein
PCN061_RS09905	COG1528	Iron-storage protein
PCN061_RS09915	COG0814	amino acid
PCN061_RS09920	COG3012	SEC-C Motif Domain Protein
PCN061_RS09920	COG3318	Belongs to the UPF0149 family
PCN061_RS09950	COG2197	response regulator
PCN061_RS09975	COG2197	response regulator
PCN061_RS09980	COG1126	abc transporter atp-binding protein
PCN061_RS09985	COG0765	amino acid transport
PCN061_RS09995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCN061_RS10005	COG1191	sigma factor activity
PCN061_RS10010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PCN061_RS10015	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PCN061_RS10020	COG1516	flagellar protein fliS
PCN061_RS10030	COG0366	Alpha amylase catalytic
PCN061_RS10040	COG2391	methyltransferase activity
PCN061_RS10045	COG0425	Belongs to the sulfur carrier protein TusA family
PCN061_RS10050	COG2135	peptidase activity
PCN061_RS10075	COG2207	Transcriptional regulator
PCN061_RS10080	COG1881	PFAM PEBP family protein
PCN061_RS10085	COG2076	Multidrug Resistance protein
PCN061_RS10105	COG1766	The M ring may be actively involved in energy transduction
PCN061_RS10110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PCN061_RS10115	COG1317	bacterial-type flagellum organization
PCN061_RS10120	COG1157	protein secretion by the type III secretion system
PCN061_RS10125	COG2882	bacterial-type flagellum organization
PCN061_RS10130	COG3144	bacterial-type flagellum assembly
PCN061_RS10135	COG1580	Controls the rotational direction of flagella during chemotaxis
PCN061_RS10140	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PCN061_RS10145	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PCN061_RS10150	COG3190	flagellar
PCN061_RS10155	COG1338	Plays a role in the flagellum-specific transport system
PCN061_RS10160	COG1987	bacterial-type flagellum assembly
PCN061_RS10165	COG1684	flagellar biosynthetic protein fliR
PCN061_RS10170	COG2197	response regulator
PCN061_RS10200	COG5475	Uncharacterized small protein (DUF2158)
PCN061_RS10205	COG2354	Protein conserved in bacteria
PCN061_RS10210	COG0697	spore germination
PCN061_RS10215	COG3727	T/G mismatch-specific endonuclease activity
PCN061_RS10220	COG0270	DNA (cytosine-5-)-methyltransferase activity
PCN061_RS10225	COG1418	mRNA catabolic process
PCN061_RS10240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PCN061_RS10255	COG2205	protein histidine kinase activity
PCN061_RS10260	COG0745	RESPONSE REGULATOR receiver
PCN061_RS10265	COG2351	hydroxyisourate hydrolase activity
PCN061_RS10280	COG3443	Belongs to the bacterial solute-binding protein 9 family
PCN061_RS10285	COG3038	cytochrome b561
PCN061_RS10340	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PCN061_RS10400	COG4932	domain protein
PCN061_RS10400	COG2373	Large extracellular alpha-helical protein
PCN061_RS10400	COG1388	LysM domain
PCN061_RS10405	COG1388	LysM domain
PCN061_RS10405	COG2373	Large extracellular alpha-helical protein
PCN061_RS10405	COG4932	domain protein
PCN061_RS10410	COG1388	LysM domain
PCN061_RS10410	COG1470	cell adhesion involved in biofilm formation
PCN061_RS10415	COG1470	cell adhesion involved in biofilm formation
PCN061_RS10415	COG1388	LysM domain
PCN061_RS10420	COG1470	cell adhesion involved in biofilm formation
PCN061_RS10420	COG1388	LysM domain
PCN061_RS10430	COG0477	Major facilitator Superfamily
PCN061_RS10435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PCN061_RS10440	COG0217	transcriptional regulatory protein
PCN061_RS10450	COG0534	Mate efflux family protein
PCN061_RS10460	COG0583	DNA-binding transcription factor activity
PCN061_RS10465	COG0583	DNA-binding transcription factor activity
PCN061_RS10475	COG1376	ErfK ybiS ycfS ynhG family protein
PCN061_RS10490	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
PCN061_RS10505	COG1735	metal-dependent hydrolase with the TIM-barrel fold
PCN061_RS10510	COG0405	Gamma-glutamyltransferase
PCN061_RS10555	COG3436	PFAM IS66 Orf2 family protein
PCN061_RS10560	COG4372	Transposase
PCN061_RS10625	COG4917	ethanolamine utilization protein
PCN061_RS10635	COG1289	transmembrane transporter activity
PCN061_RS10645	COG1686	Belongs to the peptidase S11 family
PCN061_RS10650	COG2925	Exonuclease
PCN061_RS10655	COG0425	Belongs to the sulfur carrier protein TusA family
PCN061_RS10660	COG2391	methyltransferase activity
PCN061_RS10670	COG0531	amino acid
PCN061_RS10675	COG0583	DNA-binding transcription factor activity
PCN061_RS10680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PCN061_RS10685	COG4115	mRNA cleavage
PCN061_RS10690	COG2161	toxin-antitoxin pair type II binding
PCN061_RS10710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PCN061_RS10710	COG0131	Imidazoleglycerol-phosphate dehydratase
PCN061_RS10715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PCN061_RS10730	COG0140	phosphoribosyl-ATP diphosphatase activity
PCN061_RS10730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PCN061_RS10740	COG0438	transferase activity, transferring glycosyl groups
PCN061_RS10805	COG1088	dTDP-glucose 4,6-dehydratase activity
PCN061_RS10830	COG1216	Glycosyl transferase, family 2
PCN061_RS10850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PCN061_RS10895	COG1253	flavin adenine dinucleotide binding
PCN061_RS10900	COG2982	Protein involved in outer membrane biogenesis
PCN061_RS10910	COG0572	uridine kinase
PCN061_RS10920	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PCN061_RS10925	COG0443	Heat shock 70 kDa protein
PCN061_RS10930	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
PCN061_RS10935	COG3779	Protein conserved in bacteria
PCN061_RS10940	COG0631	protein serine/threonine phosphatase activity
PCN061_RS10945	COG4245	von Willebrand factor, type A
PCN061_RS10970	COG2205	protein histidine kinase activity
PCN061_RS10975	COG0745	RESPONSE REGULATOR receiver
PCN061_RS10985	COG0826	peptidase U32
PCN061_RS11010	COG1063	alcohol dehydrogenase
PCN061_RS11020	COG3414	Phosphotransferase system galactitol-specific IIB component
PCN061_RS11025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS11040	COG1830	Aldolase
PCN061_RS11045	COG2211	Major facilitator Superfamily
PCN061_RS11050	COG1397	ADP-ribosylglycohydrolase
PCN061_RS11055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS11060	COG2188	Transcriptional regulator
PCN061_RS11065	COG3757	hydrolase, family 25
PCN061_RS11070	COG0351	phosphomethylpyrimidine kinase
PCN061_RS11085	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
PCN061_RS11090	COG5455	response to cobalt ion
PCN061_RS11095	COG3539	Fimbrial protein
PCN061_RS11100	COG3188	usher protein
PCN061_RS11105	COG3121	Chaperone
PCN061_RS11110	COG3539	Fimbrial protein
PCN061_RS11125	COG0489	protein tyrosine kinase activity
PCN061_RS11150	COG0714	Associated with various cellular activities
PCN061_RS11155	COG2425	protein containing a von Willebrand factor type A (vWA) domain
PCN061_RS11165	COG4715	Zinc finger, swim domain protein
PCN061_RS11170	COG4808	Protein conserved in bacteria
PCN061_RS11175	COG4807	Protein conserved in bacteria
PCN061_RS11180	COG3279	Response regulator of the LytR AlgR family
PCN061_RS11185	COG3275	phosphorelay sensor kinase activity
PCN061_RS11190	COG0789	Transcriptional regulator
PCN061_RS11200	COG1174	glycine betaine transport
PCN061_RS11205	COG1125	glycine betaine transport
PCN061_RS11210	COG1174	glycine betaine transport
PCN061_RS11215	COG1732	Glycine betaine
PCN061_RS11220	COG1472	Belongs to the glycosyl hydrolase 3 family
PCN061_RS11225	COG0277	FAD linked oxidase domain protein
PCN061_RS11230	COG1686	Belongs to the peptidase S11 family
PCN061_RS11240	COG0586	Pfam SNARE associated Golgi protein
PCN061_RS11245	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS11260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PCN061_RS11270	COG1346	cytolysis
PCN061_RS11280	COG2949	membrane
PCN061_RS11290	COG0493	'glutamate synthase
PCN061_RS11295	COG0167	dihydroorotate dehydrogenase activity
PCN061_RS11295	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PCN061_RS11300	COG4211	Belongs to the binding-protein-dependent transport system permease family
PCN061_RS11305	COG1129	ABC transporter
PCN061_RS11310	COG1879	ABC-type sugar transport system periplasmic component
PCN061_RS11315	COG1609	Transcriptional regulator
PCN061_RS11325	COG2311	Membrane
PCN061_RS11345	COG4771	TonB-dependent receptor
PCN061_RS11350	COG0833	amino acid
PCN061_RS11355	COG0583	DNA-binding transcription factor activity
PCN061_RS11360	COG2855	membrane
PCN061_RS11370	COG1522	sequence-specific DNA binding
PCN061_RS11370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS11375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PCN061_RS11385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCN061_RS11390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PCN061_RS11395	COG2313	pseudouridylate synthase activity
PCN061_RS11400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS11405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCN061_RS11405	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PCN061_RS11405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCN061_RS11410	COG1105	Belongs to the carbohydrate kinase PfkB family
PCN061_RS11415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS11415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS11420	COG2814	Major facilitator Superfamily
PCN061_RS11435	COG0246	Mannitol dehydrogenase
PCN061_RS11440	COG0523	cobalamin synthesis protein
PCN061_RS11445	COG0671	phosphoesterase, PA-phosphatase related
PCN061_RS11450	COG0791	NLP P60 protein
PCN061_RS11460	COG4166	transmembrane transport
PCN061_RS11465	COG4174	ABC transporter (Permease)
PCN061_RS11470	COG4239	(ABC) transporter, permease
PCN061_RS11475	COG4172	Belongs to the ABC transporter superfamily
PCN061_RS11485	COG2814	Major facilitator Superfamily
PCN061_RS11490	COG1187	pseudouridine synthase activity
PCN061_RS11495	COG1061	Type III restriction enzyme res subunit
PCN061_RS11515	COG3083	sulfuric ester hydrolase activity
PCN061_RS11525	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS11535	COG2197	response regulator
PCN061_RS11540	COG4235	cytochrome complex assembly
PCN061_RS11540	COG3088	subunit of a heme lyase
PCN061_RS11545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PCN061_RS11550	COG1138	Cytochrome C-type biogenesis protein
PCN061_RS11560	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PCN061_RS11565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PCN061_RS11570	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PCN061_RS11575	COG4133	protoheme IX ABC transporter activity
PCN061_RS11580	COG3005	denitrification pathway
PCN061_RS11585	COG3043	anaerobic respiration
PCN061_RS11590	COG0348	domain, Protein
PCN061_RS11595	COG0437	4 iron, 4 sulfur cluster binding
PCN061_RS11605	COG3062	negative regulation of establishment of protein localization
PCN061_RS11610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCN061_RS11610	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCN061_RS11630	COG4615	Cyclic peptide transporter
PCN061_RS11635	COG3385	transposase activity
PCN061_RS11640	COG3385	transposase activity
PCN061_RS11645	COG3145	DNA-N1-methyladenine dioxygenase activity
PCN061_RS11650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PCN061_RS11650	COG2169	Transcriptional regulator
PCN061_RS11655	COG1477	protein flavinylation
PCN061_RS11660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PCN061_RS11675	COG0642	Histidine kinase
PCN061_RS11675	COG2198	Histidine kinase
PCN061_RS11680	COG2197	response regulator
PCN061_RS11685	COG2205	protein histidine kinase activity
PCN061_RS11685	COG0784	Response regulator, receiver
PCN061_RS11690	COG3852	Histidine kinase
PCN061_RS11695	COG2204	response regulator
PCN061_RS11700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PCN061_RS11705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PCN061_RS11710	COG2031	fatty acid transporter
PCN061_RS11715	COG0183	Belongs to the thiolase family
PCN061_RS11720	COG4676	Protein conserved in bacteria
PCN061_RS11725	COG5445	Predicted secreted protein (DUF2300)
PCN061_RS11730	COG2373	Large extracellular alpha-helical protein
PCN061_RS11735	COG3234	Protein of unknown function (DUF1175)
PCN061_RS11740	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
PCN061_RS11745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCN061_RS11755	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS11765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCN061_RS11770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCN061_RS11775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PCN061_RS11780	COG3642	lipopolysaccharide core region biosynthetic process
PCN061_RS11785	COG0583	DNA-binding transcription factor activity
PCN061_RS11790	COG0584	glycerophosphoryl diester phosphodiesterase
PCN061_RS11795	COG2271	Major facilitator Superfamily
PCN061_RS11800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PCN061_RS11810	COG0247	lactate metabolic process
PCN061_RS11815	COG5464	transposase or invertase
PCN061_RS11830	COG2271	Major facilitator Superfamily
PCN061_RS11840	COG1414	Transcriptional regulator
PCN061_RS11905	COG0318	PFAM AMP-dependent synthetase and ligase
PCN061_RS11915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PCN061_RS11930	COG1169	isochorismate synthase
PCN061_RS11935	COG4575	ribosome binding
PCN061_RS11940	COG2153	protein acetylation
PCN061_RS11950	COG5160	protein modification by small protein removal
PCN061_RS11955	COG2304	oxidoreductase activity
PCN061_RS11960	COG2234	aminopeptidase activity
PCN061_RS11980	COG0457	Tetratricopeptide repeat
PCN061_RS11990	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCN061_RS11995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PCN061_RS12005	COG0839	Belongs to the complex I subunit 6 family
PCN061_RS12020	COG1034	ATP synthesis coupled electron transport
PCN061_RS12025	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PCN061_RS12030	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
PCN061_RS12050	COG0583	DNA-binding transcription factor activity
PCN061_RS12055	COG0436	Aminotransferase
PCN061_RS12065	COG0490	domain, Protein
PCN061_RS12065	COG0471	metal ion transport
PCN061_RS12070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PCN061_RS12090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PCN061_RS12095	COG0857	belongs to the CobB CobQ family
PCN061_RS12095	COG0280	phosphate acetyltransferase
PCN061_RS12100	COG1288	antiporter activity
PCN061_RS12105	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PCN061_RS12110	COG0622	Phosphoesterase
PCN061_RS12115	COG0625	glutathione transferase activity
PCN061_RS12120	COG0625	glutathione transferase activity
PCN061_RS12125	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PCN061_RS12130	COG1090	epimerase
PCN061_RS12135	COG5464	transposase or invertase
PCN061_RS12140	COG4598	ABC transporter
PCN061_RS12145	COG4160	amino acid transport
PCN061_RS12150	COG4215	(ABC) transporter
PCN061_RS12155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCN061_RS12160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCN061_RS12165	COG0163	prenyltransferase activity
PCN061_RS12170	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PCN061_RS12175	COG1286	toxin biosynthetic process
PCN061_RS12180	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
PCN061_RS12185	COG0285	dihydrofolate synthase activity
PCN061_RS12195	COG0586	Pfam SNARE associated Golgi protein
PCN061_RS12205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PCN061_RS12220	COG2814	Major facilitator Superfamily
PCN061_RS12225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PCN061_RS12240	COG3101	peptidyl-lysine hydroxylation
PCN061_RS12245	COG0730	response to heat
PCN061_RS12260	COG2890	protein-(glutamine-N5) methyltransferase activity
PCN061_RS12275	COG3539	Fimbrial protein
PCN061_RS12280	COG3539	Fimbrial protein
PCN061_RS12285	COG3539	Fimbrial protein
PCN061_RS12290	COG3121	Chaperone
PCN061_RS12295	COG3188	usher protein
PCN061_RS12300	COG3539	Fimbrial protein
PCN061_RS12305	COG2062	phosphohistidine phosphatase, SixA
PCN061_RS12320	COG3691	Protein conserved in bacteria
PCN061_RS12325	COG2067	long-chain fatty acid transport protein
PCN061_RS12335	COG2853	Lipoprotein
PCN061_RS12340	COG2116	formate transmembrane transporter activity
PCN061_RS12350	COG0583	DNA-binding transcription factor activity
PCN061_RS12355	COG2610	gluconate transmembrane transporter activity
PCN061_RS12365	COG0477	Major facilitator Superfamily
PCN061_RS12370	COG1566	PFAM secretion protein HlyD family protein
PCN061_RS12375	COG2197	response regulator
PCN061_RS12380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCN061_RS12380	COG2198	Histidine kinase
PCN061_RS12380	COG2205	protein histidine kinase activity
PCN061_RS12380	COG0784	Response regulator, receiver
PCN061_RS12385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PCN061_RS12390	COG0679	Auxin Efflux Carrier
PCN061_RS12395	COG0028	Belongs to the TPP enzyme family
PCN061_RS12425	COG1560	Kdo2-lipid A biosynthetic process
PCN061_RS12430	COG0436	Aminotransferase
PCN061_RS12435	COG3275	phosphorelay sensor kinase activity
PCN061_RS12440	COG3279	Response regulator of the LytR AlgR family
PCN061_RS12445	COG2207	Transcriptional regulator
PCN061_RS12450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS12450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS12450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCN061_RS12455	COG1363	Peptidase, m42
PCN061_RS12460	COG0006	proline dipeptidase activity
PCN061_RS12465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCN061_RS12470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCN061_RS12500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PCN061_RS12505	COG3385	transposase activity
PCN061_RS12510	COG3385	transposase activity
PCN061_RS12515	COG2200	EAL domain
PCN061_RS12515	COG2199	diguanylate cyclase activity
PCN061_RS12530	COG3415	Transposase
PCN061_RS12535	COG3415	Transposase
PCN061_RS12565	COG0583	DNA-binding transcription factor activity
PCN061_RS12575	COG2211	Major facilitator Superfamily
PCN061_RS12580	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PCN061_RS12590	COG0583	DNA-binding transcription factor activity
PCN061_RS12595	COG0385	Bile acid
PCN061_RS12600	COG3530	Putative quorum-sensing-regulated virulence factor
PCN061_RS12620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PCN061_RS12625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS12630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCN061_RS12635	COG2190	(PTS) system
PCN061_RS12650	COG4884	unkown
PCN061_RS12650	COG3831	ATPase activity
PCN061_RS12655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PCN061_RS12660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PCN061_RS12665	COG4208	sulfate ABC transporter
PCN061_RS12670	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PCN061_RS12675	COG4150	thiosulfate binding
PCN061_RS12680	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS12695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS12695	COG1263	PTS System
PCN061_RS12700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PCN061_RS12705	COG2837	iron assimilation
PCN061_RS12720	COG0456	acetyltransferase
PCN061_RS12725	COG0860	N-Acetylmuramoyl-L-alanine amidase
PCN061_RS12735	COG2207	Transcriptional regulator
PCN061_RS12740	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PCN061_RS12745	COG4816	utilization protein
PCN061_RS12755	COG4303	Ethanolamine ammonia lyase large subunit
PCN061_RS12760	COG4819	ethanolamine utilization protein
PCN061_RS12765	COG3192	ethanolamine utilization protein
PCN061_RS12770	COG1454	alcohol dehydrogenase
PCN061_RS12775	COG4820	ethanolamine utilization protein (EutJ)
PCN061_RS12780	COG1012	belongs to the aldehyde dehydrogenase family
PCN061_RS12785	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
PCN061_RS12790	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PCN061_RS12795	COG0280	phosphate acetyltransferase
PCN061_RS12800	COG4812	Cobalamin adenosyltransferase
PCN061_RS12805	COG4766	ethanolamine catabolic process
PCN061_RS12810	COG4917	ethanolamine utilization protein
PCN061_RS12815	COG4810	utilization protein
PCN061_RS12820	COG0280	phosphate acetyltransferase
PCN061_RS12820	COG0281	malic enzyme
PCN061_RS12825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PCN061_RS12830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PCN061_RS12835	COG5342	invasion associated locus B
PCN061_RS12845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCN061_RS12845	COG0493	'glutamate synthase
PCN061_RS12850	COG3850	Histidine kinase
PCN061_RS12855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PCN061_RS12865	COG1393	Belongs to the ArsC family
PCN061_RS12880	COG0400	carboxylic ester hydrolase activity
PCN061_RS12885	COG1444	tRNA N-acetyltransferase activity
PCN061_RS12890	COG2321	neutral zinc metallopeptidase
PCN061_RS12905	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PCN061_RS12915	COG2716	regulation of RNA biosynthetic process
PCN061_RS12920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PCN061_RS12925	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCN061_RS12930	COG0651	ATP synthesis coupled electron transport
PCN061_RS12935	COG0651	ATP synthesis coupled electron transport
PCN061_RS12940	COG0650	Formate hydrogenlyase subunit 4
PCN061_RS12945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PCN061_RS12950	COG4237	Hydrogenase 4 membrane
PCN061_RS12955	COG0651	ATP synthesis coupled electron transport
PCN061_RS12960	COG3261	NADH dehydrogenase
PCN061_RS12960	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
PCN061_RS12965	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCN061_RS12970	COG3260	NADH ubiquinone oxidoreductase 20
PCN061_RS12980	COG3604	Transcriptional regulator
PCN061_RS12985	COG2116	formate transmembrane transporter activity
PCN061_RS12990	COG0628	permease
PCN061_RS12995	COG4783	chaperone-mediated protein folding
PCN061_RS13000	COG1393	Belongs to the ArsC family
PCN061_RS13010	COG2233	PERMEase
PCN061_RS13025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PCN061_RS13030	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PCN061_RS13035	COG0248	Ppx GppA phosphatase
PCN061_RS13040	COG2801	Transposase and inactivated derivatives
PCN061_RS13045	COG2963	transposase activity
PCN061_RS13050	COG2200	EAL domain
PCN061_RS13065	COG3133	Outer membrane lipoprotein
PCN061_RS13080	COG0516	GMP reductase activity
PCN061_RS13080	COG0517	IMP dehydrogenase activity
PCN061_RS13090	COG1645	bacterial-type flagellum-dependent swarming motility
PCN061_RS13105	COG2976	Protein conserved in bacteria
PCN061_RS13135	COG4953	penicillin-binding protein 1C
PCN061_RS13140	COG2373	Large extracellular alpha-helical protein
PCN061_RS13145	COG2897	thiosulfate sulfurtransferase activity
PCN061_RS13160	COG2975	iron-sulfur cluster assembly
PCN061_RS13165	COG0633	Ferredoxin
PCN061_RS13185	COG0822	iron-sulfur transferase activity
PCN061_RS13205	COG0483	inositol monophosphate 1-phosphatase activity
PCN061_RS13210	COG1073	alpha beta
PCN061_RS13215	COG3711	transcriptional antiterminator
PCN061_RS13220	COG2814	Major facilitator Superfamily
PCN061_RS13225	COG0583	DNA-binding transcription factor activity
PCN061_RS13230	COG4638	Rieske (2fe-2S)
PCN061_RS13255	COG2259	Doxx family
PCN061_RS13260	COG2017	converts alpha-aldose to the beta-anomer
PCN061_RS13265	COG1063	alcohol dehydrogenase
PCN061_RS13270	COG1172	Belongs to the binding-protein-dependent transport system permease family
PCN061_RS13275	COG1129	ABC transporter
PCN061_RS13280	COG1879	ABC-type sugar transport system periplasmic component
PCN061_RS13285	COG0457	Tetratricopeptide repeat
PCN061_RS13290	COG1940	carbohydrate kinase activity
PCN061_RS13300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PCN061_RS13300	COG1017	nitric oxide dioxygenase activity
PCN061_RS13305	COG0347	Belongs to the P(II) protein family
PCN061_RS13310	COG2204	response regulator
PCN061_RS13315	COG3170	Tfp pilus assembly protein FimV
PCN061_RS13320	COG2205	protein histidine kinase activity
PCN061_RS13325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCN061_RS13325	COG0047	phosphoribosylformylglycinamidine synthase activity
PCN061_RS13340	COG0560	Phosphoserine phosphatase
PCN061_RS13345	COG1737	Transcriptional regulator
PCN061_RS13350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCN061_RS13375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PCN061_RS13395	COG0681	Belongs to the peptidase S26 family
PCN061_RS13405	COG3086	response to oxidative stress
PCN061_RS13410	COG3026	antisigma factor binding
PCN061_RS13415	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
PCN061_RS13420	COG1595	DNA-templated transcription, initiation
PCN061_RS13430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PCN061_RS13440	COG0513	Belongs to the DEAD box helicase family
PCN061_RS13450	COG0583	DNA-binding transcription factor activity
PCN061_RS13470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCN061_RS13480	COG3118	belongs to the thioredoxin family
PCN061_RS13485	COG3148	PFAM DTW domain containing protein
PCN061_RS13490	COG0045	succinate-CoA ligase (ADP-forming) activity
PCN061_RS13490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PCN061_RS13490	COG1042	CoA-binding domain protein
PCN061_RS13495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCN061_RS13500	COG5544	Lipoprotein
PCN061_RS13505	COG0477	Major facilitator Superfamily
PCN061_RS13535	COG0542	response to heat
PCN061_RS13540	COG1496	oxidoreductase activity
PCN061_RS13545	COG0564	pseudouridine synthase activity
PCN061_RS13550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PCN061_RS13560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PCN061_RS13565	COG0077	Prephenate dehydratase
PCN061_RS13565	COG1605	Chorismate mutase
PCN061_RS13570	COG1605	Chorismate mutase
PCN061_RS13570	COG0287	Prephenate dehydrogenase
PCN061_RS13575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PCN061_RS13590	COG2199	diguanylate cyclase activity
PCN061_RS13595	COG2885	chlorophyll binding
PCN061_RS13620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PCN061_RS13625	COG4137	Cytochrome C assembly protein
PCN061_RS13630	COG4536	flavin adenine dinucleotide binding
PCN061_RS13650	COG0497	DNA recombination
PCN061_RS13655	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PCN061_RS13665	COG2867	negative regulation of translational initiation
PCN061_RS13675	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS13680	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS13700	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS13730	COG0366	Alpha amylase catalytic
PCN061_RS13735	COG0366	Alpha amylase catalytic
PCN061_RS13740	COG0366	Alpha amylase catalytic
PCN061_RS13750	COG0579	oxidoreductase
PCN061_RS13755	COG1012	belongs to the aldehyde dehydrogenase family
PCN061_RS13760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PCN061_RS13765	COG1113	amino acid transport
PCN061_RS13770	COG1802	Transcriptional regulator
PCN061_RS13775	COG1652	LysM domain
PCN061_RS13780	COG0401	homolog of Blt101
PCN061_RS13785	COG0640	Transcriptional regulator
PCN061_RS13790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCN061_RS13795	COG2916	Histone family protein nucleoid-structuring protein H-NS
PCN061_RS13810	COG4575	ribosome binding
PCN061_RS13815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PCN061_RS13825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCN061_RS13830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCN061_RS13835	COG4175	Glycine betaine
PCN061_RS13840	COG4176	ABC-type proline glycine betaine transport system permease component
PCN061_RS13845	COG2113	Glycine betaine
PCN061_RS13850	COG2814	Major facilitator Superfamily
PCN061_RS13855	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PCN061_RS13865	COG1846	Transcriptional regulator
PCN061_RS13870	COG1566	PFAM secretion protein HlyD family protein
PCN061_RS13875	COG2814	Major facilitator Superfamily
PCN061_RS13890	COG1238	metal cluster binding
PCN061_RS13895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PCN061_RS13930	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PCN061_RS13955	COG1546	Belongs to the CinA family
PCN061_RS13960	COG2951	lytic endotransglycosylase activity
PCN061_RS13965	COG3730	PTS system glucitol sorbitol-specific
PCN061_RS13970	COG3732	PTS system glucitol sorbitol-specific
PCN061_RS13980	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS13985	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS13990	COG1349	DNA-binding transcription factor activity
PCN061_RS13995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PCN061_RS13995	COG0517	IMP dehydrogenase activity
PCN061_RS14015	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PCN061_RS14020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCN061_RS14025	COG1609	Transcriptional regulator
PCN061_RS14030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS14030	COG1263	PTS System
PCN061_RS14035	COG2723	6-phospho-beta-galactosidase activity
PCN061_RS14040	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PCN061_RS14050	COG3260	NADH ubiquinone oxidoreductase 20
PCN061_RS14055	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCN061_RS14060	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
PCN061_RS14060	COG3261	NADH dehydrogenase
PCN061_RS14065	COG0650	Formate hydrogenlyase subunit 4
PCN061_RS14070	COG0651	ATP synthesis coupled electron transport
PCN061_RS14075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCN061_RS14090	COG0375	protein maturation
PCN061_RS14095	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PCN061_RS14100	COG0298	carbon dioxide binding
PCN061_RS14105	COG0409	Hydrogenase expression formation protein
PCN061_RS14110	COG0309	Hydrogenase expression formation protein (HypE)
PCN061_RS14115	COG3604	Transcriptional regulator
PCN061_RS14135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PCN061_RS14140	COG1349	DNA-binding transcription factor activity
PCN061_RS14145	COG2084	Dehydrogenase
PCN061_RS14150	COG3395	kinase activity
PCN061_RS14155	COG0235	Class ii aldolase
PCN061_RS14160	COG3622	Belongs to the hyi family
PCN061_RS14165	COG2610	gluconate transmembrane transporter activity
PCN061_RS14170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCN061_RS14175	COG1388	LysM domain
PCN061_RS14175	COG4942	peptidase
PCN061_RS14230	COG2234	aminopeptidase activity
PCN061_RS14235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PCN061_RS14240	COG1518	maintenance of DNA repeat elements
PCN061_RS14255	COG1857	crispr-associated protein
PCN061_RS14270	COG1203	CRISPR-associated helicase, Cas3
PCN061_RS14275	COG3385	transposase activity
PCN061_RS14280	COG3385	transposase activity
PCN061_RS14295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PCN061_RS14305	COG0720	synthase
PCN061_RS14310	COG0644	oxidoreductase
PCN061_RS14315	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
PCN061_RS14320	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PCN061_RS14325	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PCN061_RS14330	COG2086	electron transfer activity
PCN061_RS14335	COG0477	Major facilitator Superfamily
PCN061_RS14340	COG0277	FAD linked oxidase domain protein
PCN061_RS14345	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS14350	COG2223	nitrite transmembrane transporter activity
PCN061_RS14355	COG1070	Carbohydrate kinase
PCN061_RS14360	COG0602	queuosine metabolic process
PCN061_RS14370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PCN061_RS14385	COG3956	TIGRFAM MazG family protein
PCN061_RS14390	COG2337	Toxic component of a toxin-antitoxin (TA) module
PCN061_RS14395	COG2336	PFAM SpoVT AbrB
PCN061_RS14400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PCN061_RS14405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCN061_RS14410	COG2205	protein histidine kinase activity
PCN061_RS14410	COG3437	response regulator, receiver
PCN061_RS14410	COG3850	Histidine kinase
PCN061_RS14410	COG4999	Histidine kinase
PCN061_RS14415	COG4948	Mandelate Racemase Muconate Lactonizing
PCN061_RS14420	COG4948	Mandelate Racemase Muconate Lactonizing
PCN061_RS14425	COG2271	Major facilitator Superfamily
PCN061_RS14430	COG0716	FMN binding
PCN061_RS14435	COG0564	pseudouridine synthase activity
PCN061_RS14440	COG3098	single-species biofilm formation
PCN061_RS14460	COG1611	Belongs to the LOG family
PCN061_RS14465	COG0814	amino acid
PCN061_RS14470	COG1760	l-serine dehydratase
PCN061_RS14480	COG1454	alcohol dehydrogenase
PCN061_RS14485	COG0235	Class ii aldolase
PCN061_RS14490	COG0738	Major facilitator superfamily
PCN061_RS14500	COG1070	Carbohydrate kinase
PCN061_RS14510	COG1349	DNA-binding transcription factor activity
PCN061_RS14520	COG2363	Small membrane protein
PCN061_RS14525	COG0583	DNA-binding transcription factor activity
PCN061_RS14535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PCN061_RS14540	COG2166	iron-sulfur cluster assembly
PCN061_RS14545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PCN061_RS14550	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PCN061_RS14570	COG0860	N-Acetylmuramoyl-L-alanine amidase
PCN061_RS14575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PCN061_RS14575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PCN061_RS14580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PCN061_RS14585	COG1074	ATP-dependent DNA helicase activity
PCN061_RS14595	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PCN061_RS14600	COG4967	type IV pilus modification protein PilV
PCN061_RS14610	COG4795	General secretion pathway protein
PCN061_RS14615	COG2165	general secretion pathway protein
PCN061_RS14630	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
PCN061_RS14655	COG0861	Integral membrane protein TerC family
PCN061_RS14665	COG0667	Aldo Keto reductase
PCN061_RS14680	COG1609	Transcriptional regulator
PCN061_RS14690	COG0583	DNA-binding transcription factor activity
PCN061_RS14695	COG1794	racemase activity, acting on amino acids and derivatives
PCN061_RS14700	COG2814	Major facilitator Superfamily
PCN061_RS14705	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS14715	COG0183	Belongs to the thiolase family
PCN061_RS14720	COG0814	amino acid
PCN061_RS14725	COG3039	Transposase
PCN061_RS14730	COG1662	PFAM IS1 transposase
PCN061_RS14745	COG4942	peptidase
PCN061_RS14750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PCN061_RS14755	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PCN061_RS14760	COG2080	2 iron, 2 sulfur cluster binding
PCN061_RS14765	COG3829	transcription factor binding
PCN061_RS14770	COG1662	PFAM IS1 transposase
PCN061_RS14780	COG2233	PERMEase
PCN061_RS14805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PCN061_RS14810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PCN061_RS14815	COG4974	Belongs to the 'phage' integrase family
PCN061_RS14820	COG0716	FMN binding
PCN061_RS14830	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PCN061_RS14840	COG1272	protein, Hemolysin III
PCN061_RS14850	COG2723	6-phospho-beta-galactosidase activity
PCN061_RS14855	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS14875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PCN061_RS14880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PCN061_RS14885	COG0006	proline dipeptidase activity
PCN061_RS14900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PCN061_RS14905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PCN061_RS14925	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PCN061_RS14925	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PCN061_RS14930	COG1703	isobutyryl-CoA mutase activity
PCN061_RS14935	COG1024	Enoyl-CoA hydratase
PCN061_RS14940	COG0427	acetyl-CoA hydrolase
PCN061_RS14945	COG0583	DNA-binding transcription factor activity
PCN061_RS14950	COG0583	DNA-binding transcription factor activity
PCN061_RS14955	COG2968	Membrane
PCN061_RS14965	COG0668	transmembrane transport
PCN061_RS14970	COG0191	fructose-bisphosphate aldolase activity
PCN061_RS14985	COG1072	(Pantothenic acid kinase))
PCN061_RS14990	COG3722	fumarate hydratase activity
PCN061_RS14995	COG1494	fructose-1,6-bisphosphatase
PCN061_RS15000	COG1063	alcohol dehydrogenase
PCN061_RS15005	COG2213	PTS system mannitol-specific
PCN061_RS15010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS15015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PCN061_RS15020	COG0501	Belongs to the peptidase M48B family
PCN061_RS15030	COG1166	arginine decarboxylase activity
PCN061_RS15055	COG2814	Major facilitator Superfamily
PCN061_RS15065	COG2356	endonuclease I
PCN061_RS15070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PCN061_RS15075	COG0189	ligase activity
PCN061_RS15090	COG2805	Type II/IV secretion system protein
PCN061_RS15095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PCN061_RS15100	COG0762	integral membrane protein
PCN061_RS15115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PCN061_RS15125	COG0252	asparaginase activity
PCN061_RS15140	COG3171	Protein conserved in bacteria
PCN061_RS15150	COG1194	a g-specific adenine glycosylase
PCN061_RS15165	COG2211	Major facilitator Superfamily
PCN061_RS15170	COG1982	Orn Lys Arg decarboxylase major
PCN061_RS15175	COG1811	Na channel or pump
PCN061_RS15185	COG0582	viral genome integration into host DNA
PCN061_RS15195	COG2801	Transposase and inactivated derivatives
PCN061_RS15205	COG3677	Transposase
PCN061_RS15215	COG1982	Orn Lys Arg decarboxylase major
PCN061_RS15220	COG0531	amino acid
PCN061_RS15245	COG0604	alcohol dehydrogenase
PCN061_RS15250	COG2963	transposase activity
PCN061_RS15255	COG3039	Transposase
PCN061_RS15260	COG2826	transposase and inactivated derivatives, IS30 family
PCN061_RS15270	COG1757	Na H antiporter
PCN061_RS15275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PCN061_RS15280	COG3039	Transposase
PCN061_RS15345	COG1454	alcohol dehydrogenase
PCN061_RS15345	COG1012	belongs to the aldehyde dehydrogenase family
PCN061_RS15355	COG1012	belongs to the aldehyde dehydrogenase family
PCN061_RS15355	COG1454	alcohol dehydrogenase
PCN061_RS15360	COG1882	Formate acetyltransferase
PCN061_RS15365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCN061_RS15375	COG4869	propanediol catabolic process
PCN061_RS15390	COG2076	Multidrug Resistance protein
PCN061_RS15395	COG1662	PFAM IS1 transposase
PCN061_RS15400	COG0754	glutathionylspermidine amidase activity
PCN061_RS15405	COG0625	glutathione transferase activity
PCN061_RS15410	COG0298	carbon dioxide binding
PCN061_RS15420	COG1773	rubredoxin
PCN061_RS15425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PCN061_RS15430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
PCN061_RS15435	COG5557	Pfam Polysulphide reductase, NrfD
PCN061_RS15440	COG0437	4 iron, 4 sulfur cluster binding
PCN061_RS15445	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
PCN061_RS15465	COG0667	Aldo Keto reductase
PCN061_RS15475	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS15480	COG0848	biopolymer transport protein
PCN061_RS15485	COG0811	peptide transport
PCN061_RS15495	COG0626	cystathionine gamma-synthase activity
PCN061_RS15500	COG0586	Pfam SNARE associated Golgi protein
PCN061_RS15505	COG2207	Transcriptional regulator
PCN061_RS15515	COG1979	alcohol dehydrogenase
PCN061_RS15520	COG0656	L-ascorbic acid biosynthetic process
PCN061_RS15530	COG4238	major outer membrane lipoprotein
PCN061_RS15535	COG1032	radical SAM domain protein
PCN061_RS15540	COG2132	Multicopper oxidase
PCN061_RS15545	COG0204	Acyl-transferase
PCN061_RS15550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCN061_RS15555	COG4166	transmembrane transport
PCN061_RS15560	COG2944	sequence-specific DNA binding
PCN061_RS15570	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PCN061_RS15575	COG3111	PFAM Bacterial OB fold (BOF) protein
PCN061_RS15580	COG0745	RESPONSE REGULATOR receiver
PCN061_RS15585	COG0642	Histidine kinase
PCN061_RS15595	COG2249	NAD(P)H dehydrogenase (quinone) activity
PCN061_RS15600	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PCN061_RS15605	COG0187	DNA topoisomerase II activity
PCN061_RS15610	COG3150	esterase
PCN061_RS15615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PCN061_RS15620	COG3151	Protein conserved in bacteria
PCN061_RS15625	COG0494	nUDIX hydrolase
PCN061_RS15630	COG1538	Outer membrane efflux protein
PCN061_RS15645	COG0754	glutathionylspermidine amidase activity
PCN061_RS15650	COG3384	dioxygenase
PCN061_RS15670	COG2960	long-chain fatty acid transporting porin activity
PCN061_RS15675	COG3539	Fimbrial protein
PCN061_RS15680	COG3188	usher protein
PCN061_RS15685	COG3121	Chaperone
PCN061_RS15690	COG3539	Fimbrial protein
PCN061_RS15700	COG1585	Membrane protein implicated in regulation of membrane protease activity
PCN061_RS15705	COG2268	Band 7 protein
PCN061_RS15730	COG3025	triphosphatase activity
PCN061_RS15740	COG4991	sh3 domain protein
PCN061_RS15760	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PCN061_RS15770	COG0583	DNA-binding transcription factor activity
PCN061_RS15775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
PCN061_RS15780	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
PCN061_RS15785	COG0471	metal ion transport
PCN061_RS15795	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PCN061_RS15800	COG0358	DNA primase activity
PCN061_RS15805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCN061_RS15855	COG2003	Belongs to the UPF0758 family
PCN061_RS15880	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS15910	COG1874	Beta-galactosidase
PCN061_RS15915	COG3867	Arabinogalactan endo-beta-1,4-galactanase
PCN061_RS15920	COG3833	ABC-type maltose transport systems, permease component
PCN061_RS15925	COG1175	transmembrane transport
PCN061_RS15930	COG2182	Extracellular solute-binding protein
PCN061_RS15965	COG4983	Phage plasmid primase, P4 family domain protein
PCN061_RS15970	COG4983	Phage plasmid primase, P4 family domain protein
PCN061_RS15995	COG2375	cellular response to nickel ion
PCN061_RS16000	COG1695	Transcriptional regulator
PCN061_RS16005	COG0840	transmembrane signaling receptor activity
PCN061_RS16015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCN061_RS16020	COG1609	Transcriptional regulator
PCN061_RS16025	COG3250	beta-galactosidase activity
PCN061_RS16030	COG2731	YhcH YjgK YiaL family protein
PCN061_RS16035	COG0531	amino acid
PCN061_RS16045	COG3408	Glycogen debranching enzyme
PCN061_RS16045	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
PCN061_RS16050	COG0446	pyridine nucleotide-disulphide oxidoreductase
PCN061_RS16050	COG1902	pentaerythritol trinitrate reductase activity
PCN061_RS16055	COG5499	transcription regulator containing HTH domain
PCN061_RS16060	COG4680	protein conserved in bacteria
PCN061_RS16075	COG1451	nucleotide metabolic process
PCN061_RS16080	COG2949	membrane
PCN061_RS16085	COG0673	inositol 2-dehydrogenase activity
PCN061_RS16090	COG0861	Integral membrane protein TerC family
PCN061_RS16095	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PCN061_RS16105	COG2721	sulfolactate sulfo-lyase activity
PCN061_RS16115	COG2271	Major facilitator Superfamily
PCN061_RS16120	COG2186	Transcriptional regulator
PCN061_RS16125	COG0586	Pfam SNARE associated Golgi protein
PCN061_RS16135	COG1422	Protein of unknown function (DUF1090)
PCN061_RS16140	COG4575	ribosome binding
PCN061_RS16145	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
PCN061_RS16155	COG2259	Doxx family
PCN061_RS16160	COG0435	Glutathione S-transferase
PCN061_RS16165	COG3152	Membrane
PCN061_RS16170	COG3152	Membrane
PCN061_RS16175	COG0583	DNA-binding transcription factor activity
PCN061_RS16180	COG1741	Belongs to the pirin family
PCN061_RS16195	COG0814	amino acid
PCN061_RS16200	COG1760	l-serine dehydratase
PCN061_RS16205	COG0251	oxidation-reduction process
PCN061_RS16210	COG1882	Formate acetyltransferase
PCN061_RS16215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PCN061_RS16225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PCN061_RS16230	COG0583	DNA-binding transcription factor activity
PCN061_RS16250	COG1929	Belongs to the glycerate kinase type-1 family
PCN061_RS16255	COG2084	Dehydrogenase
PCN061_RS16265	COG2271	Major facilitator Superfamily
PCN061_RS16270	COG2721	sulfolactate sulfo-lyase activity
PCN061_RS16275	COG2002	toxin-antitoxin pair type II binding
PCN061_RS16285	COG1349	DNA-binding transcription factor activity
PCN061_RS16295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS16305	COG3716	PTS system mannose fructose sorbose family IID component
PCN061_RS16310	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS16315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PCN061_RS16320	COG2222	sugar isomerase
PCN061_RS16330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS16335	COG3715	PTS system
PCN061_RS16340	COG3716	PTS system mannose fructose sorbose family IID component
PCN061_RS16345	COG0363	glucosamine-6-phosphate deaminase activity
PCN061_RS16350	COG3539	Fimbrial protein
PCN061_RS16355	COG3121	Chaperone
PCN061_RS16360	COG3188	usher protein
PCN061_RS16365	COG3539	Fimbrial protein
PCN061_RS16370	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PCN061_RS16375	COG3107	peptidoglycan biosynthetic process
PCN061_RS16390	COG2823	Periplasmic or secreted lipoprotein
PCN061_RS16395	COG0701	Predicted permease
PCN061_RS16400	COG0702	epimerase
PCN061_RS16405	COG0693	protein deglycase activity
PCN061_RS16420	COG3153	acetyltransferase
PCN061_RS16425	COG3154	lipid carrier protein
PCN061_RS16430	COG0826	peptidase U32
PCN061_RS16435	COG0826	peptidase U32
PCN061_RS16440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PCN061_RS16445	COG0814	amino acid
PCN061_RS16455	COG0513	Belongs to the DEAD box helicase family
PCN061_RS16490	COG0195	Participates in both transcription termination and antitermination
PCN061_RS16510	COG2194	sulfuric ester hydrolase activity
PCN061_RS16520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PCN061_RS16530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PCN061_RS16535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCN061_RS16545	COG1534	Rna-binding protein
PCN061_RS16550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PCN061_RS16555	COG2027	D-alanyl-D-alanine carboxypeptidase
PCN061_RS16565	COG0697	spore germination
PCN061_RS16580	COG0142	geranyltranstransferase activity
PCN061_RS16585	COG3423	Transcriptional regulator
PCN061_RS16595	COG5007	Belongs to the BolA IbaG family
PCN061_RS16600	COG3113	response to antibiotic
PCN061_RS16605	COG2854	intermembrane phospholipid transfer
PCN061_RS16610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PCN061_RS16615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PCN061_RS16620	COG1127	ABC transporter
PCN061_RS16625	COG0530	calcium, potassium:sodium antiporter activity
PCN061_RS16630	COG0517	IMP dehydrogenase activity
PCN061_RS16630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PCN061_RS16635	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PCN061_RS16640	COG3117	lipopolysaccharide transmembrane transporter activity
PCN061_RS16645	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PCN061_RS16650	COG1137	ATPase activity
PCN061_RS16655	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PCN061_RS16660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PCN061_RS16675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS16680	COG0515	serine threonine protein kinase
PCN061_RS16690	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PCN061_RS16695	COG5002	protein histidine kinase activity
PCN061_RS16695	COG2198	Histidine kinase
PCN061_RS16695	COG0784	Response regulator, receiver
PCN061_RS16700	COG1242	4 iron, 4 sulfur cluster binding
PCN061_RS16705	COG0070	glutamate synthase
PCN061_RS16705	COG0069	glutamate synthase activity
PCN061_RS16705	COG0067	glutamate synthase
PCN061_RS16710	COG0493	'glutamate synthase
PCN061_RS16715	COG4804	nuclease activity
PCN061_RS16725	COG2731	YhcH YjgK YiaL family protein
PCN061_RS16755	COG3069	C4-dicarboxylate transmembrane transporter activity
PCN061_RS16760	COG2969	positive regulation of protein catabolic process
PCN061_RS16765	COG0625	glutathione transferase activity
PCN061_RS16780	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PCN061_RS16785	COG3105	Protein conserved in bacteria
PCN061_RS16790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PCN061_RS16795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PCN061_RS16815	COG2732	(Barnase) inhibitor
PCN061_RS16835	COG0583	DNA-binding transcription factor activity
PCN061_RS16840	COG0312	modulator of DNA gyrase
PCN061_RS16845	COG3164	Protein of unknown function
PCN061_RS16850	COG1530	ribonuclease E activity
PCN061_RS16855	COG0424	maF-like protein
PCN061_RS16860	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PCN061_RS16865	COG1792	Involved in formation and maintenance of cell shape
PCN061_RS16870	COG1077	Cell shape determining protein MreB Mrl
PCN061_RS16880	COG2200	EAL domain
PCN061_RS16880	COG2199	diguanylate cyclase activity
PCN061_RS16885	COG0604	alcohol dehydrogenase
PCN061_RS16900	COG0511	ligase activity, forming carbon-carbon bonds
PCN061_RS16905	COG0439	Biotin carboxylase
PCN061_RS16910	COG3924	membrane
PCN061_RS16915	COG4145	pantothenate transmembrane transporter activity
PCN061_RS16925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PCN061_RS16935	COG2189	Belongs to the N(4) N(6)-methyltransferase family
PCN061_RS16945	COG1309	transcriptional regulator
PCN061_RS16950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCN061_RS16955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PCN061_RS16970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCN061_RS16975	COG4597	amino acid ABC transporter
PCN061_RS16980	COG0765	amino acid transport
PCN061_RS16985	COG1126	abc transporter atp-binding protein
PCN061_RS17025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PCN061_RS17045	COG0551	DNA topoisomerase type I activity
PCN061_RS17055	COG0758	DNA mediated transformation
PCN061_RS17075	COG0569	domain protein
PCN061_RS17085	COG3036	rescue of stalled ribosome
PCN061_RS17090	COG0789	Transcriptional regulator
PCN061_RS17130	COG0201	protein transport
PCN061_RS17220	COG0089	rRNA binding
PCN061_RS17245	COG3267	Type II secretory pathway component ExeA
PCN061_RS17245	COG3409	Peptidoglycan-binding domain 1 protein
PCN061_RS17255	COG1450	Type ii and iii secretion system protein
PCN061_RS17260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PCN061_RS17265	COG1459	type II secretion system
PCN061_RS17270	COG2165	general secretion pathway protein
PCN061_RS17275	COG2165	general secretion pathway protein
PCN061_RS17280	COG2165	general secretion pathway protein
PCN061_RS17285	COG4795	General secretion pathway protein
PCN061_RS17290	COG3156	type II secretion system protein K
PCN061_RS17295	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
PCN061_RS17300	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
PCN061_RS17305	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PCN061_RS17310	COG2193	ferroxidase activity
PCN061_RS17315	COG2906	2 iron, 2 sulfur cluster binding
PCN061_RS17320	COG3979	chitinase
PCN061_RS17360	COG2964	Protein conserved in bacteria
PCN061_RS17365	COG0545	Peptidyl-prolyl cis-trans isomerase
PCN061_RS17375	COG1047	Peptidyl-prolyl cis-trans
PCN061_RS17380	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PCN061_RS17395	COG0488	(ABC) transporter
PCN061_RS17400	COG0429	hydrolase of the alpha beta-hydrolase fold
PCN061_RS17410	COG3954	Phosphoribulokinase
PCN061_RS17415	COG1765	OsmC-like protein
PCN061_RS17425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCN061_RS17430	COG1289	transmembrane transporter activity
PCN061_RS17435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PCN061_RS17440	COG0512	Glutamine amidotransferase of anthranilate synthase
PCN061_RS17445	COG2184	nucleotidyltransferase activity
PCN061_RS17460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PCN061_RS17470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PCN061_RS17475	COG2146	nitrite reductase [NAD(P)H] activity
PCN061_RS17480	COG2116	formate transmembrane transporter activity
PCN061_RS17495	COG0531	amino acid
PCN061_RS17500	COG2222	sugar isomerase
PCN061_RS17505	COG1082	Xylose isomerase domain protein TIM barrel
PCN061_RS17510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS17515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS17520	COG2188	Transcriptional regulator
PCN061_RS17525	COG0626	cystathionine gamma-synthase activity
PCN061_RS17540	COG1735	metal-dependent hydrolase with the TIM-barrel fold
PCN061_RS17545	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PCN061_RS17550	COG3457	Alanine racemase
PCN061_RS17560	COG2188	Transcriptional regulator
PCN061_RS17565	COG0180	Tryptophanyl-tRNA synthetase
PCN061_RS17570	COG0546	phosphoglycolate phosphatase activity
PCN061_RS17575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PCN061_RS17580	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PCN061_RS17585	COG3266	domain, Protein
PCN061_RS17600	COG4796	Type ii and iii secretion system protein
PCN061_RS17615	COG3166	PFAM Fimbrial assembly family protein
PCN061_RS17625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PCN061_RS17630	COG0494	nUDIX hydrolase
PCN061_RS17640	COG1011	Hydrolase
PCN061_RS17645	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PCN061_RS17655	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PCN061_RS17680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PCN061_RS17685	COG2183	response to ionizing radiation
PCN061_RS17690	COG1918	ferrous iron import across plasma membrane
PCN061_RS17695	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PCN061_RS17705	COG5464	transposase or invertase
PCN061_RS17725	COG2610	gluconate transmembrane transporter activity
PCN061_RS17730	COG1640	4-alpha-glucanotransferase
PCN061_RS17735	COG0058	SHG alpha-glucan phosphorylase activity
PCN061_RS17750	COG1690	Belongs to the RtcB family
PCN061_RS17755	COG4650	regulator
PCN061_RS17765	COG4650	regulator
PCN061_RS17770	COG1349	DNA-binding transcription factor activity
PCN061_RS17785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PCN061_RS17800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PCN061_RS17805	COG0058	SHG alpha-glucan phosphorylase activity
PCN061_RS17830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PCN061_RS17835	COG2095	MarC family integral membrane protein
PCN061_RS17840	COG2610	gluconate transmembrane transporter activity
PCN061_RS17845	COG3265	gluconokinase activity
PCN061_RS17850	COG1609	Transcriptional regulator
PCN061_RS17855	COG1741	Belongs to the pirin family
PCN061_RS17860	COG0673	inositol 2-dehydrogenase activity
PCN061_RS17865	COG1247	-acetyltransferase
PCN061_RS17875	COG0405	Gamma-glutamyltransferase
PCN061_RS17885	COG0584	glycerophosphoryl diester phosphodiesterase
PCN061_RS17890	COG3842	ATPase activity
PCN061_RS17900	COG1175	transmembrane transport
PCN061_RS17905	COG1653	transport
PCN061_RS17915	COG0410	ABC transporter
PCN061_RS17920	COG0411	ABC transporter
PCN061_RS17925	COG4177	L-phenylalanine transmembrane transporter activity
PCN061_RS17930	COG0559	Belongs to the binding-protein-dependent transport system permease family
PCN061_RS17935	COG0683	leucine binding
PCN061_RS17940	COG0456	acetyltransferase
PCN061_RS17950	COG0683	leucine binding
PCN061_RS17955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCN061_RS17960	COG2177	Part of the ABC transporter FtsEX involved in
PCN061_RS17965	COG2884	Cell division ATP-binding protein ftsE
PCN061_RS17970	COG0552	protein localization to endoplasmic reticulum
PCN061_RS17975	COG0742	ribosomal rna small subunit methyltransferase
PCN061_RS17980	COG3776	membrane
PCN061_RS17990	COG3714	YhhN family
PCN061_RS18005	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PCN061_RS18020	COG0628	permease
PCN061_RS18025	COG2091	lysine biosynthetic process via aminoadipic acid
PCN061_RS18030	COG0747	negative chemotaxis
PCN061_RS18035	COG0601	transmembrane transport
PCN061_RS18040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCN061_RS18045	COG0444	Belongs to the ABC transporter superfamily
PCN061_RS18060	COG3209	COG3209 Rhs family protein
PCN061_RS18075	COG5433	transposase activity
PCN061_RS18085	COG0842	Transport permease protein
PCN061_RS18090	COG1129	ABC transporter
PCN061_RS18090	COG0842	Transport permease protein
PCN061_RS18095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCN061_RS18125	COG2081	HI0933 family
PCN061_RS18130	COG0306	phosphate transporter
PCN061_RS18140	COG0589	response to stress
PCN061_RS18145	COG3104	oligopeptide transport
PCN061_RS18155	COG0339	signal peptide processing
PCN061_RS18160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PCN061_RS18165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCN061_RS18180	COG0640	Transcriptional regulator
PCN061_RS18185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PCN061_RS18190	COG1393	Belongs to the ArsC family
PCN061_RS18200	COG3065	identical protein binding
PCN061_RS18205	COG2197	response regulator
PCN061_RS18210	COG1285	pathogenesis
PCN061_RS18225	COG3247	response to pH
PCN061_RS18230	COG2771	luxR family
PCN061_RS18240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCN061_RS18245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PCN061_RS18250	COG2207	Transcriptional regulator
PCN061_RS18255	COG2207	Transcriptional regulator
PCN061_RS18260	COG0076	glutamate decarboxylase activity
PCN061_RS18265	COG1858	cytochrome C peroxidase
PCN061_RS18275	COG2197	response regulator
PCN061_RS18280	COG0583	DNA-binding transcription factor activity
PCN061_RS18285	COG1295	ribonuclease BN
PCN061_RS18290	COG0477	Major facilitator Superfamily
PCN061_RS18295	COG2982	Protein involved in outer membrane biogenesis
PCN061_RS18300	COG2200	EAL domain
PCN061_RS18310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS18315	COG0612	Peptidase, M16
PCN061_RS18325	COG2199	diguanylate cyclase activity
PCN061_RS18325	COG2200	EAL domain
PCN061_RS18330	COG3118	belongs to the thioredoxin family
PCN061_RS18330	COG0457	Tetratricopeptide repeat
PCN061_RS18335	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PCN061_RS18340	COG1215	transferase activity, transferring glycosyl groups
PCN061_RS18345	COG1215	transferase activity, transferring glycosyl groups
PCN061_RS18375	COG2194	sulfuric ester hydrolase activity
PCN061_RS18400	COG0814	amino acid
PCN061_RS18405	COG4608	Belongs to the ABC transporter superfamily
PCN061_RS18410	COG0444	Belongs to the ABC transporter superfamily
PCN061_RS18415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCN061_RS18420	COG0601	transmembrane transport
PCN061_RS18430	COG0747	negative chemotaxis
PCN061_RS18445	COG2194	sulfuric ester hydrolase activity
PCN061_RS18450	COG2223	nitrite transmembrane transporter activity
PCN061_RS18455	COG5571	outer membrane autotransporter
PCN061_RS18460	COG2818	Glycosylase
PCN061_RS18465	COG0456	acetyltransferase
PCN061_RS18470	COG0243	molybdopterin cofactor binding
PCN061_RS18475	COG2885	chlorophyll binding
PCN061_RS18490	COG2944	sequence-specific DNA binding
PCN061_RS18495	COG1278	Cold shock
PCN061_RS18505	COG2963	transposase activity
PCN061_RS18510	COG2801	Transposase and inactivated derivatives
PCN061_RS18530	COG3274	enterobacterial common antigen metabolic process
PCN061_RS18535	COG4682	membrane
PCN061_RS18550	COG4682	membrane
PCN061_RS18555	COG1070	Carbohydrate kinase
PCN061_RS18565	COG4213	ABC transporter substrate-binding protein
PCN061_RS18570	COG1129	ABC transporter
PCN061_RS18575	COG4214	carbohydrate transport
PCN061_RS18580	COG1609	Transcriptional regulator
PCN061_RS18580	COG2207	Transcriptional regulator
PCN061_RS18585	COG2992	FlgJ-related protein
PCN061_RS18590	COG0366	Alpha amylase catalytic
PCN061_RS18595	COG3977	Valine--pyruvate aminotransferase
PCN061_RS18605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCN061_RS18610	COG1414	Transcriptional regulator
PCN061_RS18620	COG2731	YhcH YjgK YiaL family protein
PCN061_RS18625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PCN061_RS18635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PCN061_RS18640	COG1070	Carbohydrate kinase
PCN061_RS18645	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
PCN061_RS18650	COG3623	hexulose-6-phosphate isomerase
PCN061_RS18655	COG0235	Class ii aldolase
PCN061_RS18660	COG3713	MltA-interacting MipA family protein
PCN061_RS18665	COG0583	DNA-binding transcription factor activity
PCN061_RS18670	COG1566	PFAM secretion protein HlyD family protein
PCN061_RS18685	COG1012	belongs to the aldehyde dehydrogenase family
PCN061_RS18695	COG3276	selenocysteine insertion sequence binding
PCN061_RS18705	COG0625	glutathione transferase activity
PCN061_RS18710	COG3209	COG3209 Rhs family protein
PCN061_RS18720	COG1413	lyase activity
PCN061_RS18725	COG3209	COG3209 Rhs family protein
PCN061_RS18730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PCN061_RS18740	COG1566	PFAM secretion protein HlyD family protein
PCN061_RS18750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS18750	COG2213	PTS system mannitol-specific
PCN061_RS18760	COG3722	fumarate hydratase activity
PCN061_RS18780	COG5295	Hep Hag repeat protein
PCN061_RS18785	COG1620	l-lactate permease
PCN061_RS18790	COG2186	Transcriptional regulator
PCN061_RS18800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PCN061_RS18805	COG1045	serine acetyltransferase
PCN061_RS18820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PCN061_RS18825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCN061_RS18835	COG4942	peptidase
PCN061_RS18840	COG2861	carbohydrate metabolic process
PCN061_RS18845	COG1216	Glycosyl transferase, family 2
PCN061_RS18855	COG0156	8-amino-7-oxononanoate synthase activity
PCN061_RS18865	COG0859	PFAM glycosyl transferase family 9
PCN061_RS18870	COG0859	PFAM glycosyl transferase family 9
PCN061_RS18875	COG3307	-O-antigen
PCN061_RS18880	COG1216	Glycosyl transferase, family 2
PCN061_RS18885	COG1442	glycosyl transferase family 8
PCN061_RS18890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PCN061_RS18905	COG0515	serine threonine protein kinase
PCN061_RS18910	COG0438	transferase activity, transferring glycosyl groups
PCN061_RS18915	COG0859	PFAM glycosyl transferase family 9
PCN061_RS18920	COG1519	Transferase
PCN061_RS18950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PCN061_RS18975	COG1561	YicC-like family, N-terminal region
PCN061_RS19000	COG3561	AntA/AntB antirepressor
PCN061_RS19070	COG2860	membrane
PCN061_RS19080	COG0194	GDP metabolic process
PCN061_RS19090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PCN061_RS19095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCN061_RS19100	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PCN061_RS19105	COG0786	glutamate:sodium symporter activity
PCN061_RS19110	COG2233	PERMEase
PCN061_RS19115	COG2982	Protein involved in outer membrane biogenesis
PCN061_RS19125	COG2211	Major facilitator Superfamily
PCN061_RS19140	COG2814	Major facilitator Superfamily
PCN061_RS19145	COG0697	spore germination
PCN061_RS19150	COG1464	Belongs to the NlpA lipoprotein family
PCN061_RS19175	COG2252	PERMEase
PCN061_RS19185	COG2271	Major facilitator Superfamily
PCN061_RS19190	COG2271	Major facilitator Superfamily
PCN061_RS19195	COG3851	Histidine kinase
PCN061_RS19200	COG2197	response regulator
PCN061_RS19205	COG0440	acetolactate synthase activity
PCN061_RS19210	COG0028	Belongs to the TPP enzyme family
PCN061_RS19235	COG2814	Major facilitator Superfamily
PCN061_RS19240	COG0641	radical SAM
PCN061_RS19250	COG2149	membrane
PCN061_RS19255	COG0675	Transposase, IS605 OrfB family
PCN061_RS19275	COG2188	Transcriptional regulator
PCN061_RS19300	COG5645	(Lipo)protein
PCN061_RS19305	COG0823	Involved in the tonB-independent uptake of proteins
PCN061_RS19315	COG2271	Major facilitator Superfamily
PCN061_RS19325	COG0800	Aldolase
PCN061_RS19330	COG3734	2-keto-3-deoxy-galactonokinase
PCN061_RS19335	COG2186	Transcriptional regulator
PCN061_RS19345	COG0561	phosphatase activity
PCN061_RS19350	COG3753	Protein conserved in bacteria
PCN061_RS19360	COG0187	DNA topoisomerase II activity
PCN061_RS19370	COG0592	DNA-directed DNA polymerase activity
PCN061_RS19420	COG0814	amino acid
PCN061_RS19435	COG2091	lysine biosynthetic process via aminoadipic acid
PCN061_RS19440	COG0431	NADPH-dependent FMN reductase
PCN061_RS19445	COG2252	PERMEase
PCN061_RS19450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PCN061_RS19460	COG3196	Protein conserved in bacteria
PCN061_RS19465	COG0363	glucosamine-6-phosphate deaminase activity
PCN061_RS19470	COG2382	esterase
PCN061_RS19480	COG2723	6-phospho-beta-galactosidase activity
PCN061_RS19485	COG2190	(PTS) system
PCN061_RS19485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS19485	COG1263	PTS System
PCN061_RS19490	COG3711	transcriptional antiterminator
PCN061_RS19495	COG0704	Plays a role in the regulation of phosphate uptake
PCN061_RS19500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PCN061_RS19505	COG0581	inorganic phosphate transmembrane transporter activity
PCN061_RS19510	COG0573	inorganic phosphate transmembrane transporter activity
PCN061_RS19515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PCN061_RS19520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PCN061_RS19570	COG3312	ion transport
PCN061_RS19585	COG0716	FMN binding
PCN061_RS19590	COG1522	sequence-specific DNA binding
PCN061_RS19620	COG1129	ABC transporter
PCN061_RS19625	COG1172	Belongs to the binding-protein-dependent transport system permease family
PCN061_RS19630	COG1879	ABC-type sugar transport system periplasmic component
PCN061_RS19635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS19640	COG1609	Transcriptional regulator
PCN061_RS19645	COG0477	Major facilitator Superfamily
PCN061_RS19650	COG2186	Transcriptional regulator
PCN061_RS19690	COG3085	chromosome segregation
PCN061_RS19695	COG0606	chelatase, subunit chli
PCN061_RS19710	COG3978	acetolactate synthase activity
PCN061_RS19715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PCN061_RS19725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PCN061_RS19730	COG0583	DNA-binding transcription factor activity
PCN061_RS19740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PCN061_RS19750	COG0210	DNA helicase
PCN061_RS19765	COG3118	belongs to the thioredoxin family
PCN061_RS19775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PCN061_RS19785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PCN061_RS19790	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
PCN061_RS19795	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PCN061_RS19800	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PCN061_RS19805	COG1088	dTDP-glucose 4,6-dehydratase activity
PCN061_RS19810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PCN061_RS19815	COG0456	acetyltransferase
PCN061_RS19820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PCN061_RS19825	COG2244	polysaccharide biosynthetic process
PCN061_RS19845	COG1113	amino acid transport
PCN061_RS19870	COG0641	radical SAM
PCN061_RS19875	COG3119	arylsulfatase activity
PCN061_RS19880	COG3071	HemY protein
PCN061_RS19885	COG2959	enzyme of heme biosynthesis
PCN061_RS19890	COG1587	Uroporphyrinogen-III synthase
PCN061_RS19900	COG3072	Adenylate cyclase
PCN061_RS19925	COG5567	small periplasmic lipoprotein
PCN061_RS19935	COG3159	Protein conserved in bacteria
PCN061_RS19945	COG1011	Hydrolase
PCN061_RS19950	COG0210	DNA helicase
PCN061_RS19955	COG3698	Phosphodiester glycosidase
PCN061_RS19965	COG0598	Magnesium transport protein CorA
PCN061_RS19980	COG2962	Rard protein
PCN061_RS19985	COG2050	protein possibly involved in aromatic compounds catabolism
PCN061_RS19990	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
PCN061_RS19995	COG0514	ATP-dependent DNA helicase (RecQ)
PCN061_RS20000	COG1280	lysine exporter protein (LysE YggA)
PCN061_RS20005	COG1280	lysine exporter protein (LysE YggA)
PCN061_RS20010	COG2267	carboxylic ester hydrolase activity
PCN061_RS20015	COG0561	phosphatase activity
PCN061_RS20020	COG0697	spore germination
PCN061_RS20025	COG0583	DNA-binding transcription factor activity
PCN061_RS20035	COG0412	Dienelactone hydrolase
PCN061_RS20040	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
PCN061_RS20045	COG1322	Protein conserved in bacteria
PCN061_RS20055	COG3165	ubiquinone biosynthetic process from chorismate
PCN061_RS20065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PCN061_RS20070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PCN061_RS20075	COG0805	protein transport
PCN061_RS20080	COG0084	hydrolase, TatD family'
PCN061_RS20085	COG0250	Participates in transcription elongation, termination and antitermination
PCN061_RS20095	COG0543	2 iron, 2 sulfur cluster binding
PCN061_RS20115	COG1739	Uncharacterized protein family UPF0029
PCN061_RS20120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PCN061_RS20125	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
PCN061_RS20155	COG1763	Mo-molybdopterin cofactor biosynthetic process
PCN061_RS20160	COG0746	molybdenum cofactor guanylyltransferase activity
PCN061_RS20165	COG3084	Protein conserved in bacteria
PCN061_RS20170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PCN061_RS20175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PCN061_RS20180	COG5339	Protein conserved in bacteria
PCN061_RS20185	COG0204	Acyl-transferase
PCN061_RS20195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCN061_RS20195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCN061_RS20205	COG3078	GTPase activator activity
PCN061_RS20210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PCN061_RS20220	COG2204	response regulator
PCN061_RS20225	COG3852	Histidine kinase
PCN061_RS20230	COG0174	glutamine synthetase
PCN061_RS20240	COG1217	gtp-binding protein TYPA
PCN061_RS20245	COG2188	Transcriptional regulator
PCN061_RS20250	COG1082	Xylose isomerase domain protein TIM barrel
PCN061_RS20255	COG2271	Major facilitator Superfamily
PCN061_RS20260	COG1349	DNA-binding transcription factor activity
PCN061_RS20265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCN061_RS20270	COG2084	Dehydrogenase
PCN061_RS20275	COG3684	Belongs to the aldolase LacD family
PCN061_RS20280	COG1063	alcohol dehydrogenase
PCN061_RS20290	COG0477	Major facilitator Superfamily
PCN061_RS20300	COG1011	Hydrolase
PCN061_RS20315	COG0456	acetyltransferase
PCN061_RS20325	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PCN061_RS20330	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PCN061_RS20345	COG2864	formate dehydrogenase
PCN061_RS20350	COG0437	4 iron, 4 sulfur cluster binding
PCN061_RS20355	COG0243	molybdopterin cofactor binding
PCN061_RS20355	COG3383	formate dehydrogenase (NAD+) activity
PCN061_RS20360	COG0243	molybdopterin cofactor binding
PCN061_RS20360	COG3383	formate dehydrogenase (NAD+) activity
PCN061_RS20420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PCN061_RS20435	COG2258	MOSC domain
PCN061_RS20440	COG2205	protein histidine kinase activity
PCN061_RS20445	COG0745	RESPONSE REGULATOR receiver
PCN061_RS20450	COG3678	ATP-independent chaperone mediated protein folding
PCN061_RS20465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PCN061_RS20485	COG3152	Membrane
PCN061_RS20490	COG3691	Protein conserved in bacteria
PCN061_RS20495	COG0589	response to stress
PCN061_RS20500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PCN061_RS20505	COG1494	fructose-1,6-bisphosphatase
PCN061_RS20515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PCN061_RS20530	COG1575	Belongs to the MenA family. Type 1 subfamily
PCN061_RS20545	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PCN061_RS20550	COG1609	Transcriptional regulator
PCN061_RS20555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PCN061_RS20570	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PCN061_RS20580	COG0626	cystathionine gamma-synthase activity
PCN061_RS20585	COG0460	homoserine dehydrogenase
PCN061_RS20585	COG0527	aspartate kinase activity
PCN061_RS20595	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PCN061_RS20605	COG0697	spore germination
PCN061_RS20610	COG3738	Protein conserved in bacteria
PCN061_RS20620	COG0371	Dehydrogenase
PCN061_RS20625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PCN061_RS20630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCN061_RS20630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS20630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS20635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCN061_RS20640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCN061_RS20645	COG1882	Formate acetyltransferase
PCN061_RS20650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCN061_RS20655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCN061_RS20660	COG2207	Transcriptional regulator
PCN061_RS20665	COG2194	sulfuric ester hydrolase activity
PCN061_RS20680	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PCN061_RS20695	COG0583	DNA-binding transcription factor activity
PCN061_RS20720	COG4206	TonB-dependent receptor
PCN061_RS20755	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PCN061_RS20755	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PCN061_RS20795	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PCN061_RS20800	COG0250	Participates in transcription elongation, termination and antitermination
PCN061_RS20835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PCN061_RS20845	COG2104	thiamine diphosphate biosynthetic process
PCN061_RS20850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PCN061_RS20885	COG3068	Protein conserved in bacteria
PCN061_RS20900	COG3678	ATP-independent chaperone mediated protein folding
PCN061_RS20905	COG4191	Histidine kinase
PCN061_RS20910	COG2204	response regulator
PCN061_RS20915	COG0151	Belongs to the GarS family
PCN061_RS20950	COG0456	acetyltransferase
PCN061_RS20960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PCN061_RS20965	COG2224	Isocitrate lyase
PCN061_RS20985	COG1414	Transcriptional regulator
PCN061_RS20990	COG1410	methionine synthase
PCN061_RS20990	COG0646	methionine synthase
PCN061_RS20995	COG1283	sodium-dependent phosphate transmembrane transporter activity
PCN061_RS21005	COG1187	pseudouridine synthase activity
PCN061_RS21015	COG0527	aspartate kinase activity
PCN061_RS21030	COG3833	ABC-type maltose transport systems, permease component
PCN061_RS21035	COG1175	transmembrane transport
PCN061_RS21040	COG2182	Extracellular solute-binding protein
PCN061_RS21050	COG3842	ATPase activity
PCN061_RS21070	COG1357	PFAM Pentapeptide repeats (8 copies)
PCN061_RS21090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PCN061_RS21100	COG0534	Mate efflux family protein
PCN061_RS21105	COG3237	CsbD-like
PCN061_RS21110	COG0735	belongs to the Fur family
PCN061_RS21125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PCN061_RS21135	COG0604	alcohol dehydrogenase
PCN061_RS21140	COG0305	Participates in initiation and elongation during chromosome replication
PCN061_RS21145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PCN061_RS21150	COG1448	Aminotransferase
PCN061_RS21160	COG3700	Belongs to the class B bacterial acid phosphatase family
PCN061_RS21165	COG0432	Pfam Uncharacterised protein family UPF0047
PCN061_RS21170	COG2315	Protein conserved in bacteria
PCN061_RS21175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PCN061_RS21180	COG0629	single-stranded DNA binding
PCN061_RS21190	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PCN061_RS21195	COG2207	Transcriptional regulator
PCN061_RS21200	COG0789	Transcriptional regulator
PCN061_RS21205	COG2252	PERMEase
PCN061_RS21210	COG0025	NhaP-type Na H and K H
PCN061_RS21215	COG1357	PFAM Pentapeptide repeats (8 copies)
PCN061_RS21225	COG3162	membrane
PCN061_RS21230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PCN061_RS21240	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
PCN061_RS21245	COG0437	4 iron, 4 sulfur cluster binding
PCN061_RS21250	COG3301	Polysulphide reductase, NrfD
PCN061_RS21255	COG1138	Cytochrome C-type biogenesis protein
PCN061_RS21260	COG3088	subunit of a heme lyase
PCN061_RS21265	COG4235	cytochrome complex assembly
PCN061_RS21270	COG1301	dicarboxylic acid transport
PCN061_RS21275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PCN061_RS21280	COG3383	formate dehydrogenase (NAD+) activity
PCN061_RS21285	COG3383	formate dehydrogenase (NAD+) activity
PCN061_RS21290	COG1538	Outer membrane efflux protein
PCN061_RS21295	COG1289	transmembrane transporter activity
PCN061_RS21300	COG1566	PFAM secretion protein HlyD family protein
PCN061_RS21310	COG2015	COG2015, Alkyl sulfatase and related hydrolases
PCN061_RS21315	COG1940	carbohydrate kinase activity
PCN061_RS21320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PCN061_RS21325	COG1172	Belongs to the binding-protein-dependent transport system permease family
PCN061_RS21330	COG1129	ABC transporter
PCN061_RS21335	COG1879	ABC-type sugar transport system periplasmic component
PCN061_RS21340	COG1737	Transcriptional regulator
PCN061_RS21345	COG0698	ribose 5-phosphate isomerase
PCN061_RS21355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PCN061_RS21360	COG0456	acetyltransferase
PCN061_RS21365	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
PCN061_RS21370	COG3454	Phosphonate metabolism
PCN061_RS21375	COG4778	phosphonate C-P lyase system protein PhnL
PCN061_RS21380	COG4107	phosphonate C-P lyase system protein PhnK
PCN061_RS21385	COG3627	carbon phosphorus lyase activity
PCN061_RS21390	COG3626	phosphonate metabolism
PCN061_RS21395	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
PCN061_RS21400	COG3624	Phosphonate C-P lyase system protein PhnG
PCN061_RS21405	COG2188	Transcriptional regulator
PCN061_RS21410	COG3639	organic phosphonate transmembrane transporter activity
PCN061_RS21415	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PCN061_RS21425	COG2764	glyoxalase bleomycin resistance protein dioxygenase
PCN061_RS21430	COG2824	Alkylphosphonate utilization operon protein PhnA
PCN061_RS21445	COG0477	Major facilitator Superfamily
PCN061_RS21455	COG0642	Histidine kinase
PCN061_RS21460	COG0745	RESPONSE REGULATOR receiver
PCN061_RS21465	COG2194	sulfuric ester hydrolase activity
PCN061_RS21470	COG0531	amino acid
PCN061_RS21475	COG2207	Transcriptional regulator
PCN061_RS21480	COG1982	Orn Lys Arg decarboxylase major
PCN061_RS21485	COG2169	Transcriptional regulator
PCN061_RS21495	COG1486	melibiose metabolic process
PCN061_RS21500	COG2211	Major facilitator Superfamily
PCN061_RS21505	COG3647	Membrane
PCN061_RS21510	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
PCN061_RS21510	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
PCN061_RS21515	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PCN061_RS21525	COG4565	transcriptional regulatory protein
PCN061_RS21530	COG3290	protein histidine kinase activity
PCN061_RS21535	COG3592	Divergent 4Fe-4S mono-cluster
PCN061_RS21540	COG2388	GCN5-related N-acetyl-transferase
PCN061_RS21570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PCN061_RS21575	COG3104	oligopeptide transport
PCN061_RS21580	COG1982	Orn Lys Arg decarboxylase major
PCN061_RS21585	COG0531	amino acid
PCN061_RS21590	COG3710	Transcriptional regulator
PCN061_RS21600	COG1309	transcriptional regulator
PCN061_RS21605	COG4232	protein-disulfide reductase activity
PCN061_RS21615	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PCN061_RS21620	COG1027	Aspartate ammonia-lyase
PCN061_RS21625	COG3030	protein affecting phage T7 exclusion by the F plasmid
PCN061_RS21630	COG0531	amino acid
PCN061_RS21655	COG1509	lysine 2,3-aminomutase activity
PCN061_RS21665	COG5510	response to toxic substance
PCN061_RS21670	COG5510	response to toxic substance
PCN061_RS21675	COG2076	Multidrug Resistance protein
PCN061_RS21680	COG3040	lipid binding
PCN061_RS21685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PCN061_RS21700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PCN061_RS21705	COG1053	succinate dehydrogenase
PCN061_RS21715	COG0531	amino acid
PCN061_RS21730	COG1511	domain protein
PCN061_RS21730	COG3264	Mechanosensitive ion channel
PCN061_RS21765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PCN061_RS21770	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PCN061_RS21770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PCN061_RS21775	COG0802	atpase or kinase
PCN061_RS21780	COG0860	N-Acetylmuramoyl-L-alanine amidase
PCN061_RS21800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PCN061_RS21805	COG0330	HflC and HflK could
PCN061_RS21810	COG0330	HflC and HflK could
PCN061_RS21815	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
PCN061_RS21830	COG0557	exoribonuclease II activity
PCN061_RS21835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCN061_RS21840	COG3789	protein conserved in bacteria
PCN061_RS21845	COG1842	Phage shock protein A
PCN061_RS21855	COG3766	membrane
PCN061_RS21860	COG5463	Belongs to the UPF0441 family
PCN061_RS21865	COG0754	glutathionylspermidine amidase activity
PCN061_RS21870	COG1960	acyl-CoA dehydrogenase activity
PCN061_RS21880	COG3650	response to hydrogen peroxide
PCN061_RS21885	COG1073	alpha beta
PCN061_RS21900	COG3037	sugar-specific permease SgaT UlaA
PCN061_RS21905	COG3414	Phosphotransferase system galactitol-specific IIB component
PCN061_RS21950	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PCN061_RS21960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PCN061_RS21970	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PCN061_RS21975	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PCN061_RS21980	COG4670	ketone body catabolic process
PCN061_RS21985	COG1024	Enoyl-CoA hydratase
PCN061_RS22000	COG1309	transcriptional regulator
PCN061_RS22005	COG3061	Opacity-associated protein A
PCN061_RS22010	COG0545	Peptidyl-prolyl cis-trans isomerase
PCN061_RS22015	COG1113	amino acid transport
PCN061_RS22025	COG0697	spore germination
PCN061_RS22030	COG0702	epimerase
PCN061_RS22035	COG1733	regulation of RNA biosynthetic process
PCN061_RS22040	COG0737	Belongs to the 5'-nucleotidase family
PCN061_RS22045	COG1218	3'(2'),5'-bisphosphate nucleotidase
PCN061_RS22050	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
PCN061_RS22060	COG1253	flavin adenine dinucleotide binding
PCN061_RS22075	COG0729	surface antigen
PCN061_RS22080	COG2911	Protein conserved in bacteria
PCN061_RS22085	COG2105	PFAM AIG2 family protein
PCN061_RS22090	COG2336	PFAM SpoVT AbrB
PCN061_RS22095	COG2337	Toxic component of a toxin-antitoxin (TA) module
PCN061_RS22100	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PCN061_RS22105	COG1879	ABC-type sugar transport system periplasmic component
PCN061_RS22110	COG1129	ABC transporter
PCN061_RS22115	COG1172	Belongs to the binding-protein-dependent transport system permease family
PCN061_RS22120	COG1172	Belongs to the binding-protein-dependent transport system permease family
PCN061_RS22130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PCN061_RS22140	COG0312	modulator of DNA gyrase
PCN061_RS22145	COG3783	Cytochrome b(562)
PCN061_RS22150	COG0602	queuosine metabolic process
PCN061_RS22155	COG1328	CTP reductase activity
PCN061_RS22160	COG0366	Alpha amylase catalytic
PCN061_RS22165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCN061_RS22165	COG1263	PTS System
PCN061_RS22170	COG1609	Transcriptional regulator
PCN061_RS22175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PCN061_RS22180	COG0251	oxidation-reduction process
PCN061_RS22205	COG0251	oxidation-reduction process
PCN061_RS22210	COG1028	Short-chain dehydrogenase reductase Sdr
PCN061_RS22215	COG1309	transcriptional regulator
PCN061_RS22220	COG2731	YhcH YjgK YiaL family protein
PCN061_RS22235	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PCN061_RS22240	COG0456	acetyltransferase
PCN061_RS22245	COG4269	membrane
PCN061_RS22250	COG0525	valine-tRNA ligase activity
PCN061_RS22255	COG2927	DNA polymerase III (CHI subunit)
PCN061_RS22265	COG0795	lipopolysaccharide-transporting ATPase activity
PCN061_RS22270	COG0795	lipopolysaccharide-transporting ATPase activity
PCN061_RS22275	COG0433	COG0433 Predicted ATPase
PCN061_RS22280	COG1064	alcohol dehydrogenase
PCN061_RS22290	COG0582	viral genome integration into host DNA
PCN061_RS22295	COG2194	sulfuric ester hydrolase activity
PCN061_RS22400	COG2916	Histone family protein nucleoid-structuring protein H-NS
PCN061_RS22415	COG3328	transposase activity
PCN061_RS22435	COG2801	Transposase and inactivated derivatives
PCN061_RS22445	COG3596	GTP binding
PCN061_RS22455	COG2378	regulation of single-species biofilm formation
PCN061_RS22480	COG2003	Belongs to the UPF0758 family
PCN061_RS22510	COG0582	viral genome integration into host DNA
PCN061_RS22525	COG3436	PFAM IS66 Orf2 family protein
PCN061_RS22530	COG4372	Transposase
PCN061_RS22535	COG3547	Transposase (IS116 IS110 IS902 family)
PCN061_RS22540	COG4372	Transposase
PCN061_RS22555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCN061_RS22565	COG3037	sugar-specific permease SgaT UlaA
PCN061_RS22580	COG0738	Major facilitator superfamily
PCN061_RS22590	COG1349	DNA-binding transcription factor activity
PCN061_RS22595	COG0440	acetolactate synthase activity
PCN061_RS22600	COG0440	acetolactate synthase activity
PCN061_RS22620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PCN061_RS22640	COG1662	PFAM IS1 transposase
PCN061_RS22645	COG4974	Belongs to the 'phage' integrase family
PCN061_RS22660	COG3539	Fimbrial protein
PCN061_RS22665	COG3121	Chaperone
PCN061_RS22670	COG3188	usher protein
PCN061_RS22675	COG3539	Fimbrial protein
PCN061_RS22680	COG3539	Fimbrial protein
PCN061_RS22685	COG3539	Fimbrial protein
PCN061_RS22690	COG2610	gluconate transmembrane transporter activity
PCN061_RS22705	COG0246	Mannitol dehydrogenase
PCN061_RS22715	COG2186	Transcriptional regulator
PCN061_RS22735	COG0583	DNA-binding transcription factor activity
PCN061_RS22740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PCN061_RS22745	COG0700	Nucleoside recognition
PCN061_RS22750	COG3366	ferrous iron transmembrane transporter activity
PCN061_RS22760	COG0477	Major facilitator Superfamily
PCN061_RS22775	COG1924	4 iron, 4 sulfur cluster binding
PCN061_RS22780	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
PCN061_RS22785	COG2733	membrane
PCN061_RS22790	COG2814	Major facilitator Superfamily
PCN061_RS22820	COG0523	cobalamin synthesis protein
PCN061_RS22825	COG2879	small protein
PCN061_RS22830	COG1966	Carbon starvation protein
PCN061_RS22845	COG0840	transmembrane signaling receptor activity
PCN061_RS22850	COG2271	Major facilitator Superfamily
PCN061_RS22860	COG1802	Transcriptional regulator
PCN061_RS22865	COG1063	alcohol dehydrogenase
PCN061_RS22880	COG1484	DNA-dependent DNA replication
PCN061_RS22895	COG2966	Psort location CytoplasmicMembrane, score
PCN061_RS22900	COG2197	response regulator
PCN061_RS22905	COG2197	response regulator
PCN061_RS22910	COG4114	ferric iron reductase
PCN061_RS22945	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
PCN061_RS22950	COG0456	acetyltransferase
PCN061_RS22955	COG1011	Hydrolase
PCN061_RS22965	COG2823	Periplasmic or secreted lipoprotein
PCN061_RS22975	COG4667	esterase of the alpha-beta hydrolase superfamily
PCN061_RS22980	COG0084	hydrolase, TatD family'
PCN061_RS22985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCN061_RS22990	COG1328	CTP reductase activity
PCN061_RS23030	COG3726	membrane protein affecting hemolysin expression
PCN061_RS23035	COG0560	Phosphoserine phosphatase
PCN061_RS23040	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PCN061_RS23045	COG3172	ATPase kinase involved in NAD metabolism
PCN061_RS23045	COG1056	cytidyltransferase-related domain
PCN061_RS23055	COG0488	(ABC) transporter
PCN061_RS23060	COG0741	lytic transglycosylase activity
PCN061_RS23080	COG3708	Transcriptional regulator
PCN061_RS23080	COG2207	Transcriptional regulator
PCN061_RS23085	COG3045	CreA protein
PCN061_RS23090	COG0745	RESPONSE REGULATOR receiver
PCN061_RS23095	COG2205	protein histidine kinase activity
PCN061_RS23100	COG4452	Inner membrane protein CreD
PCN061_RS23105	COG0745	RESPONSE REGULATOR receiver
PCN061_RS23115	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PCN061_RS23185	COG0460	homoserine dehydrogenase
PCN061_RS23185	COG0527	aspartate kinase activity
PCN061_RS23205	COG0527	aspartate kinase activity
PCN061_RS23205	COG0460	homoserine dehydrogenase
PCN061_RS23210	COG0527	aspartate kinase activity
PCN061_RS23210	COG0460	homoserine dehydrogenase
PCN061_RS23245	COG0460	homoserine dehydrogenase
PCN061_RS23245	COG0527	aspartate kinase activity
PCN061_RS23485	COG0527	aspartate kinase activity
PCN061_RS23485	COG0460	homoserine dehydrogenase
PCN061_RS23525	COG0521	Mo-molybdopterin cofactor biosynthetic process
PCN061_RS23715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PCN061_RS23720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PCN061_RS23855	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PCN061_RS23890	COG0417	DNA replication proofreading
PCN061_RS24210	COG0196	riboflavin kinase activity
PCN061_RS24335	COG0644	oxidoreductase
PCN061_RS24415	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PCN061_RS24465	COG0417	DNA replication proofreading
PCN061_RS24525	COG1178	ABC-type Fe3 transport system permease component
PCN061_RS24560	COG0473	3-isopropylmalate dehydrogenase activity
PCN061_RS24770	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PCN061_RS24785	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PCN061_RS24850	COG2132	Multicopper oxidase
PCN061_RS24865	COG3468	outer membrane autotransporter barrel domain protein
PCN061_RS24875	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1