locus-tag class description FNZ59_RS00010 ENOG4105VZ1 Replication Protein FNZ59_RS00020 ENOG4105ED4 portal protein FNZ59_RS00045 ENOG4105ZTC transcriptional activator, Ogr delta FNZ59_RS00050 ENOG4105C6N Formate acetyltransferase FNZ59_RS00055 ENOG4105TMB Formate nitrite transporter FNZ59_RS00060 ENOG4105DDY UPF0142 protein ycaO FNZ59_RS00065 ENOG4107VMU Membrane FNZ59_RS00080 ENOG4108K0D peptidase, M48 FNZ59_RS00090 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FNZ59_RS00100 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 FNZ59_RS00105 ENOG4105BZ1 (ABC) transporter FNZ59_RS00110 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) FNZ59_RS00115 ENOG4105T0Z Conserved Protein FNZ59_RS00130 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups FNZ59_RS00135 ENOG4107S90 membrAne FNZ59_RS00140 ENOG4106371 Methyltransferase FNZ59_RS00150 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) FNZ59_RS00155 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) FNZ59_RS00160 ENOG4105DIT ErfK YbiS YcfS YnhG family protein FNZ59_RS00165 ENOG4105EAQ (twin-arginine translocation) pathway signal FNZ59_RS00170 ENOG4105C5X domain protein FNZ59_RS00175 ENOG4105CGF Aromatic amino acid aminotransferase FNZ59_RS00180 ENOG4105FCK Membrane FNZ59_RS00195 ENOG4105CD8 aminopeptidase N FNZ59_RS00200 ENOG4105E2Y ABC, transporter FNZ59_RS00205 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FNZ59_RS00220 ENOG4108UZX fmn reductase FNZ59_RS00225 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon FNZ59_RS00230 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae FNZ59_RS00235 ENOG4105CW0 outer membrane usher protein FNZ59_RS00240 ENOG4108MDY Fimbrial FNZ59_RS00245 ENOG4105Q7J Fimbrial FNZ59_RS00250 ENOG4105MX3 Fimbrial FNZ59_RS00255 ENOG4106PH7 chaperone FNZ59_RS00265 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) FNZ59_RS00270 ENOG4105QVC MOSC domain-containing protein FNZ59_RS00280 ENOG4105C5H ABC transporter FNZ59_RS00285 ENOG4105F1S paraquat-inducible protein a FNZ59_RS00290 ENOG4105DY2 Paraquat-inducible protein b FNZ59_RS00295 ENOG4108Q2G (LipO)protein FNZ59_RS00300 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) FNZ59_RS00310 ENOG4105DAN ATP-dependent protease FNZ59_RS00320 ENOG4105UYK outer membrane protein a FNZ59_RS00330 ENOG4108RZ1 DNA transformation protein FNZ59_RS00335 ENOG4105EM2 membrane FNZ59_RS00340 ENOG410901E Membrane FNZ59_RS00345 ENOG41088T4 Helicase IV FNZ59_RS00360 ENOG4105K4P CoA-binding domain protein FNZ59_RS00375 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FNZ59_RS00380 ENOG4108Z0T Part of a sulfur-relay system (By similarity) FNZ59_RS00385 ENOG4108MN8 Membrane FNZ59_RS00395 ENOG4105E3S small subunit FNZ59_RS00400 ENOG4105DPX Hydrogenase, large subunit FNZ59_RS00405 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit FNZ59_RS00410 ENOG4108USZ hydrogenase FNZ59_RS00415 ENOG4108VXY Hydrogenase-1 operon protein HyaE FNZ59_RS00420 ENOG4105MVP hydrogenase-1 operon protein HyaF FNZ59_RS00425 ENOG4105C4M (Ubiquinol oxidase) subunit I FNZ59_RS00430 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FNZ59_RS00440 ENOG4105D6F Phosphatase FNZ59_RS00445 ENOG4105D75 Capsular exopolysaccharide family FNZ59_RS00450 ENOG4107ZF2 Phosphatase FNZ59_RS00455 ENOG4105DAY polysaccharide export protein FNZ59_RS00460 ENOG4105E3R (LipO)protein FNZ59_RS00465 ENOG4108W78 Pfam:DUF1017 FNZ59_RS00470 ENOG4108Y9B (LipO)protein FNZ59_RS00485 ENOG41060EU Cold shock-like protein FNZ59_RS00490 ENOG4105VEQ Cold shock protein FNZ59_RS00505 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation FNZ59_RS00510 ENOG4105HEE Binding Domain protein FNZ59_RS00515 ENOG4105BZU Histidine kinase FNZ59_RS00520 ENOG4108SV3 Tmao reductase system periplasmic protein tort FNZ59_RS00525 ENOG4106WF9 DNA-binding transcriptional regulator TorR FNZ59_RS00530 ENOG4105CUW cytochrome C-TYPE protein FNZ59_RS00535 ENOG4107QY8 reductase FNZ59_RS00565 ENOG4105D6F Phosphatase FNZ59_RS00570 ENOG4105XH3 FNZ59_RS00580 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 FNZ59_RS00585 ENOG4105C2W permease FNZ59_RS00600 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) FNZ59_RS00610 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) FNZ59_RS00615 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) FNZ59_RS00620 ENOG4108R86 Transcriptional regulator FNZ59_RS00625 ENOG4105C26 Dehydrogenase FNZ59_RS00635 ENOG4105CK7 Sodium proline symporter FNZ59_RS00640 ENOG4105EKT )-iron permease FNZ59_RS00645 ENOG410650H (LipO)protein FNZ59_RS00650 ENOG4105DBE peroxidase FNZ59_RS00655 ENOG4105D5M phosphate starvation-inducible protein FNZ59_RS00660 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD FNZ59_RS00665 ENOG4105CND Glycosyl transferase, family 2 FNZ59_RS00670 ENOG4107BJW polysaccharide deacetylase FNZ59_RS00675 ENOG4108TUY outer membrane protein PgaA FNZ59_RS00680 ENOG4105BZU Histidine kinase FNZ59_RS00705 ENOG4107XHZ cytoplasmic chaperone TorD family protein FNZ59_RS00710 ENOG4108UQ5 membrane protein YcdZ FNZ59_RS00715 ENOG4105P8Q Curli production assembly transport component CsgG FNZ59_RS00720 ENOG4108WYR Curli production assembly transport component, CsgF FNZ59_RS00725 ENOG4108XDW curli assembly protein CsgE FNZ59_RS00730 ENOG41086KC Transcriptional regulator FNZ59_RS00735 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers FNZ59_RS00740 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin FNZ59_RS00745 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) FNZ59_RS00755 ENOG4108UVJ appr-1-p processing domain protein FNZ59_RS00760 ENOG4107RZC phospholipase d FNZ59_RS00775 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) FNZ59_RS00780 ENOG4105NAC (LipO)protein FNZ59_RS00785 ENOG4108W47 Acidic protein msyB FNZ59_RS00795 ENOG4105D1S lipid A biosynthesis FNZ59_RS00805 ENOG4108YYC ycei family FNZ59_RS00810 ENOG4105DS1 cytochrome b561 FNZ59_RS00815 ENOG4106974 biofilm formation FNZ59_RS00825 ENOG4105PVA Biofilm formation regulatory protein BssS FNZ59_RS00830 ENOG4105MEA DNA damage-inducible protein i FNZ59_RS00840 ENOG4105F3T (LipO)protein FNZ59_RS00845 ENOG4105E9S glutaredoxin 2 FNZ59_RS00855 ENOG4105D9U N-acetyltransferase FNZ59_RS00865 ENOG4105EP9 oxidoreductase FNZ59_RS00870 ENOG4105CJR Integral membrane protein (MviN FNZ59_RS00875 ENOG4105QVD Flagella synthesis protein FlgN FNZ59_RS00880 ENOG4105M9M anti-sigma28 factor FlgM FNZ59_RS00885 ENOG4105CKS Flagella basal body P-ring formation protein flgA FNZ59_RS00890 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FNZ59_RS00895 ENOG4108ZC9 flagellar basal-body rod protein flgc FNZ59_RS00900 ENOG4105W00 Flagellar hook capping protein FNZ59_RS00905 ENOG4105BZE flagellar hook protein, FlgE FNZ59_RS00910 ENOG4108KPB Flagellar basal-body rod protein FlgF FNZ59_RS00915 ENOG4105CGA flagellar basal-body rod protein FlgG FNZ59_RS00930 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FNZ59_RS00935 ENOG4105E1Q flagellar hook-associated protein FNZ59_RS00940 ENOG4105DTJ flagellar hook-associated protein FNZ59_RS00945 ENOG4107QQB Ribonuclease E FNZ59_RS00950 ENOG4105EI2 Pseudouridine synthase FNZ59_RS00955 ENOG4108UHJ MAF-like protein FNZ59_RS00960 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FNZ59_RS00980 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FNZ59_RS00985 ENOG4105CHR reductase FNZ59_RS00990 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FNZ59_RS00995 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FNZ59_RS01000 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FNZ59_RS01005 ENOG4105HHA aminodeoxychorismate lyase FNZ59_RS01015 ENOG4107QRG dna polymerase iii FNZ59_RS01020 ENOG4105F8V Hydrolase, tatD family FNZ59_RS01025 ENOG4105CI1 PTS System FNZ59_RS01030 ENOG4105CNM Receptor FNZ59_RS01035 ENOG4105K59 histidine triad (HIT) protein FNZ59_RS01040 ENOG41090DQ Lipoprotein FNZ59_RS01045 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) FNZ59_RS01065 ENOG4105CEP NADH dehydrogenase FNZ59_RS01070 ENOG4107MBR 17 kDa surface antigen FNZ59_RS01075 ENOG4108IND Tetr family transcriptional regulator FNZ59_RS01080 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction FNZ59_RS01085 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FNZ59_RS01090 ENOG4108JA2 transcriptioN-repair coupling factor FNZ59_RS01095 ENOG4105IQC Inner membrane protein YcfT FNZ59_RS01100 ENOG4105D60 lipoprotein releasing system transmembrane protein FNZ59_RS01105 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FNZ59_RS01110 ENOG4105D60 lipoprotein releasing system transmembrane protein FNZ59_RS01120 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FNZ59_RS01135 ENOG4107RUE extracellular solute-binding protein family 1 FNZ59_RS01140 ENOG4105D38 putrescine abc transporter FNZ59_RS01145 ENOG4105F38 ABC transporter, permease FNZ59_RS01160 ENOG4105EZE Cupin 4 family protein FNZ59_RS01165 ENOG4105IFJ Histidine kinase FNZ59_RS01170 ENOG4105XJC Two component transcriptional regulator (Winged helix family FNZ59_RS01175 ENOG4107QTF adenylosuccinate lyase FNZ59_RS01195 ENOG4108R99 pseudouridine synthase FNZ59_RS01200 ENOG4108HMX isocitrate dehydrogenase (NADP) FNZ59_RS01215 ENOG41064WM Uncharacterized protein YcgX FNZ59_RS01220 ENOG4108XDN Transcriptional regulator FNZ59_RS01230 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component FNZ59_RS01235 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB FNZ59_RS01245 ENOG410738I uncharacterized protein ymgC FNZ59_RS01250 ENOG4105BZU Histidine kinase FNZ59_RS01270 ENOG410658X FNZ59_RS01305 ENOG4107QMS site-determining protein FNZ59_RS01315 ENOG4105S66 prophage protein FNZ59_RS01320 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium FNZ59_RS01330 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FNZ59_RS01345 ENOG4105KT5 UmuD protein FNZ59_RS01350 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FNZ59_RS01355 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) FNZ59_RS01370 ENOG4105ED1 spovr family FNZ59_RS01380 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FNZ59_RS01395 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FNZ59_RS01405 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) FNZ59_RS01425 ENOG4105VDH Dihydroxyacetone kinase FNZ59_RS01430 ENOG4108UTZ Dihydroxyacetone kinase FNZ59_RS01435 ENOG4105CMT Dihydroxyacetone kinase FNZ59_RS01440 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FNZ59_RS01445 ENOG4105I1J Autotransporter FNZ59_RS01450 ENOG4105C3G gtp-binding protein FNZ59_RS01460 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria FNZ59_RS01465 ENOG4105CHH sulfate transporter FNZ59_RS01470 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FNZ59_RS01495 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FNZ59_RS01500 ENOG4108YY7 Invasion gene expression up-regulator SirB FNZ59_RS01505 ENOG41063JG Transcriptional regulator FNZ59_RS01525 ENOG4105EWV Sodium calcium exchanger membrane region FNZ59_RS01530 ENOG4105WS7 Cation transport regulator FNZ59_RS01535 ENOG4108NH8 Cation transport protein FNZ59_RS01540 ENOG41090EX DsrE family FNZ59_RS01545 ENOG4105ID0 Putative invasin FNZ59_RS01550 ENOG4105WH1 Two component transcriptional regulator luxr family FNZ59_RS01555 ENOG4105BZU Histidine kinase FNZ59_RS01560 ENOG4105DQQ Major facilitator superfamily MFS_1 FNZ59_RS01565 ENOG4105CRU nitrate reductase, alpha subunit FNZ59_RS01570 ENOG4108IUE nitrate reductase beta subunit FNZ59_RS01575 ENOG4105R3A Nitrate reductase FNZ59_RS01580 ENOG41076YT nitrate reductase, gamma subunit FNZ59_RS01620 ENOG4105CIY formyltetrahydrofolate deformylase FNZ59_RS01630 ENOG4105D78 K07001 NTE family protein FNZ59_RS01635 ENOG4105I93 response regulator FNZ59_RS01640 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FNZ59_RS01645 ENOG4108SAU DNA-binding protein H-ns FNZ59_RS01650 ENOG4107104 thymidine kinase FNZ59_RS01655 ENOG4108EKI Dehydrogenase FNZ59_RS01660 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FNZ59_RS01670 ENOG4108J59 Extracellular solute-binding protein, family 5 FNZ59_RS01680 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FNZ59_RS01685 ENOG4105C3U ABC transporter FNZ59_RS01690 ENOG4108JQ7 (ABC) transporter FNZ59_RS01710 ENOG4107SVH Potassium channel protein FNZ59_RS01715 ENOG4105K9H YciI-like protein FNZ59_RS01720 ENOG410822N TonB family FNZ59_RS01725 ENOG4105NAU thioesterase Superfamily protein FNZ59_RS01745 ENOG4105EIF outer membrane protein W FNZ59_RS01750 ENOG4108N8X transition metal ion binding FNZ59_RS01755 ENOG4108Z9Z response to DNA damage stimulus FNZ59_RS01775 ENOG4105DK0 Indole-3-glycerol phosphate synthase FNZ59_RS01780 ENOG4108EFP Anthranilate synthase component II FNZ59_RS01785 ENOG4105CRQ synthase (Component I) FNZ59_RS01795 ENOG4105DB7 PHP domain protein FNZ59_RS01800 ENOG4107RTD sua5 ycio yrdc ywlc family protein FNZ59_RS01805 ENOG4105EG3 transmembrane signal peptide protein FNZ59_RS01810 ENOG4105FE9 pseudouridine synthase FNZ59_RS01815 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FNZ59_RS01820 ENOG4105UBK short-chain dehydrogenase reductase FNZ59_RS01825 ENOG4105ERU peptidase FNZ59_RS01830 ENOG4105RKX Protein of unknown function (DUF2498) FNZ59_RS01835 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FNZ59_RS01840 ENOG4107R11 Transcriptional regulator FNZ59_RS01860 ENOG4107QM5 aconitate hydratase FNZ59_RS01870 ENOG4105EYK Phosphatidylglycerophosphatase B FNZ59_RS01875 ENOG4105Q4A inner membrane protein yciS FNZ59_RS01880 ENOG4105CFV Tetratricopeptide repeat protein FNZ59_RS01890 ENOG4108ZJT translation initiation factor, Sui1 FNZ59_RS01895 ENOG41061RM osmotically inducible lipoprotein FNZ59_RS01900 ENOG4105N2W Transcriptional regulator FNZ59_RS01910 ENOG4105BZU Histidine kinase FNZ59_RS01925 ENOG4105Q4T oxidoreductase FNZ59_RS01930 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FNZ59_RS01935 ENOG4105WDY DNA (cytosine-5-)-methyltransferase FNZ59_RS01940 ENOG4108JQ2 peptide transport system atp-binding protein FNZ59_RS01945 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein FNZ59_RS01950 ENOG4108EU3 peptide transport system, permease FNZ59_RS01955 ENOG4108I5W peptide transport system, permease protein FNZ59_RS01960 ENOG4108HIY periplasmic FNZ59_RS01965 ENOG4105N0E Protein of unknown function (DUF2543) FNZ59_RS01970 ENOG4105CUB amino acid FNZ59_RS01980 ENOG4105CFQ glutamine synthetase FNZ59_RS01985 ENOG4108Z86 Glutamine amidotransferase FNZ59_RS01990 ENOG4107VRI Transcriptional regulator FNZ59_RS01995 ENOG4105C26 Dehydrogenase FNZ59_RS02000 ENOG4105CJP fad dependent oxidoreductase FNZ59_RS02010 ENOG4105E51 psp operon transcriptional activator FNZ59_RS02015 ENOG41087YS Phage shock protein A FNZ59_RS02020 ENOG4105YYT phage shock protein B FNZ59_RS02025 ENOG4105FM1 phage shock protein C FNZ59_RS02030 ENOG4105NNG Peripheral inner membrane phage-shock protein FNZ59_RS02035 ENOG4105K8Z Phage shock protein FNZ59_RS02040 ENOG4107QW3 Sucrose phosphorylase FNZ59_RS02045 ENOG4105WEM extracellular solute-binding protein FNZ59_RS02050 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component FNZ59_RS02055 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FNZ59_RS02060 ENOG4107RRD Dehydrogenase FNZ59_RS02065 ENOG4107TYA transient receptor potential locus FNZ59_RS02070 ENOG4105CK5 oxidoreductase FNZ59_RS02075 ENOG4105C71 hydrolase family 65, central catalytic FNZ59_RS02080 ENOG4107URF beta-phospho-glucomutase FNZ59_RS02085 ENOG4108IJ9 (ABC) transporter FNZ59_RS02090 ENOG4107EFV Outer membrane protein G FNZ59_RS02095 ENOG4105FKQ transcriptional regulator FNZ59_RS02100 ENOG4105CM6 amino acid regulated cytosolic protein FNZ59_RS02110 ENOG4108JU8 Transcriptional regulator FNZ59_RS02115 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FNZ59_RS02120 ENOG4107S8C mandelate racemase muconate lactonizing FNZ59_RS02125 ENOG4105KXI murein peptide amidase A FNZ59_RS02140 ENOG4105ENX hydrolase FNZ59_RS02145 ENOG4105EQ2 LysR family Transcriptional regulator FNZ59_RS02150 ENOG4107QSI ABC, transporter FNZ59_RS02155 ENOG4105D64 Mechanosensitive ion channel FNZ59_RS02160 ENOG4105S5I Membrane FNZ59_RS02165 ENOG4105Q9Y Universal stress protein FNZ59_RS02170 ENOG4105DS0 Transcriptional regulator, Crp Fnr family FNZ59_RS02175 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FNZ59_RS02180 ENOG4105CFC Transporter FNZ59_RS02190 ENOG4105CH2 amidohydrolase FNZ59_RS02195 ENOG4106KR7 LysR family Transcriptional regulator FNZ59_RS02200 ENOG4108DG9 Smr protein MutS2 FNZ59_RS02205 ENOG4105BZU Histidine kinase FNZ59_RS02215 ENOG4105C1J atp-dependent rna helicase FNZ59_RS02220 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) FNZ59_RS02225 ENOG4107R08 Integrase FNZ59_RS02230 ENOG4107160 Rac prophage FNZ59_RS02235 ENOG41070YT Rac prophage FNZ59_RS02240 ENOG4106YAH restriction alleviation and modification enhancement FNZ59_RS02245 ENOG4108PNI recT protein FNZ59_RS02260 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FNZ59_RS02275 ENOG4105W3V DNA-binding, transcriptional regulator FNZ59_RS02290 ENOG4108RW8 Universal stress protein F FNZ59_RS02295 ENOG4105FCK Membrane FNZ59_RS02300 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FNZ59_RS02310 ENOG41090X5 Heat shock protein hslJ FNZ59_RS02315 ENOG4105C5I Dehydrogenase FNZ59_RS02320 ENOG4107H52 Dicarboxylate transport FNZ59_RS02325 ENOG410689M (LipO)protein FNZ59_RS02330 ENOG4105WXT Conserved Protein FNZ59_RS02335 ENOG4108WFR AraC Family Transcriptional Regulator FNZ59_RS02340 ENOG4105C26 Dehydrogenase FNZ59_RS02345 ENOG4105F11 amine oxidase FNZ59_RS02350 ENOG4105DXM phenylacetic acid degradation protein FNZ59_RS02355 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FNZ59_RS02360 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit FNZ59_RS02365 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FNZ59_RS02370 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FNZ59_RS02375 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FNZ59_RS02380 ENOG4105E39 Enoyl-CoA hydratase FNZ59_RS02385 ENOG4108UKI Enoyl-CoA hydratase FNZ59_RS02390 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FNZ59_RS02395 ENOG4108ZJI phenylacetic acid degradation protein FNZ59_RS02400 ENOG4105CHU acetyl-coa acetyltransferase FNZ59_RS02410 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein FNZ59_RS02415 ENOG4108Z0R Transferase FNZ59_RS02430 ENOG4107EF2 surface-exposed virulence protein FNZ59_RS02435 ENOG4107S5I aldo keto reductase FNZ59_RS02445 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase FNZ59_RS02450 ENOG4108HPI phosphatidate Cytidylyltransferase FNZ59_RS02455 ENOG4105E8V Alpha Beta Hydrolase Fold protein FNZ59_RS02460 ENOG41077RS Phosphatase FNZ59_RS02470 ENOG4105CQ7 ATP-dependent helicase FNZ59_RS02475 ENOG4107DB1 DUF218 domain FNZ59_RS02480 ENOG4105C26 Dehydrogenase FNZ59_RS02485 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FNZ59_RS02490 ENOG4105CPW cytochrome b561 FNZ59_RS02495 ENOG4105UPP uncharacterized protein ydcA FNZ59_RS02500 ENOG4107NK6 Hok/gef family FNZ59_RS02510 ENOG4105C8Q Methyl-accepting chemotaxis FNZ59_RS02515 ENOG4105DDW LysR family Transcriptional regulator FNZ59_RS02520 ENOG4105E32 cytoplasmic protein FNZ59_RS02530 ENOG4105Z2P Protein of unknown function (DUF465) FNZ59_RS02535 ENOG4108Z9I -acetyltransferase FNZ59_RS02540 ENOG4107WE3 acetyltransferase YdcK FNZ59_RS02545 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein FNZ59_RS02550 ENOG41088CC tellurite resistance protein tehB FNZ59_RS02555 ENOG4108KKZ (LipO)protein FNZ59_RS02565 ENOG4105D7V transposase FNZ59_RS02570 ENOG4105DKK Benzoate FNZ59_RS02575 ENOG4108JCI Transcriptional regulator FNZ59_RS02580 ENOG4105CFP Peptidase U32 FNZ59_RS02585 ENOG4105RR0 Protein of unknown function (DUF2554) FNZ59_RS02610 ENOG4105F9F transposase FNZ59_RS02625 ENOG4105F9F transposase FNZ59_RS02795 ENOG4107TII Recombinase FNZ59_RS02815 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FNZ59_RS02820 ENOG4107TYH extracellular solute-binding protein family 1 FNZ59_RS02825 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FNZ59_RS02830 ENOG4105D81 ABC transporter, permease FNZ59_RS02835 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component FNZ59_RS02850 ENOG410654E Membrane FNZ59_RS02855 ENOG4105R71 cytoplasmic protein FNZ59_RS02870 ENOG4108T9Y Inner membrane protein ydcZ FNZ59_RS02875 ENOG4108Z7F N-acetyltransferase FNZ59_RS02880 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FNZ59_RS02885 ENOG4108WYP Transcriptional regulator FNZ59_RS02890 ENOG4105CHB tonB-dependent Receptor FNZ59_RS02895 ENOG4108NS2 receptor FNZ59_RS02900 ENOG4105C85 amino acid FNZ59_RS02905 ENOG4108N27 Glutathione S-transferase FNZ59_RS02960 ENOG4108MEJ flavin reductase domain protein FNZ59_RS02965 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FNZ59_RS02975 ENOG4105D0D Nitrate reductase 2, gamma subunit FNZ59_RS02980 ENOG4108NZN Respiratory nitrate reductase 2 delta chain FNZ59_RS02985 ENOG4108IUE nitrate reductase beta subunit FNZ59_RS02990 ENOG4105CRU nitrate reductase, alpha subunit FNZ59_RS02995 ENOG4107QND Nitrite extrusion protein FNZ59_RS03010 ENOG4105RPH Inner membrane protein YddG FNZ59_RS03020 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FNZ59_RS03025 ENOG4108MG3 formate dehydrogenase FNZ59_RS03030 ENOG41084S7 Plasmid maintenance system antidote protein FNZ59_RS03045 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein FNZ59_RS03050 ENOG4105TPS biofilm-dependent modulation protein FNZ59_RS03055 ENOG4108Z9K Osmotically inducible protein FNZ59_RS03060 ENOG4107H6U ABC transporter FNZ59_RS03065 ENOG4105C3U ABC transporter FNZ59_RS03070 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FNZ59_RS03075 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FNZ59_RS03080 ENOG4105DEF Extracellular solute-binding protein, family 5 FNZ59_RS03085 ENOG4108UQS dipeptidase FNZ59_RS03090 ENOG4105BZU Histidine kinase FNZ59_RS03100 ENOG4105F9F transposase FNZ59_RS03110 ENOG4105F32 YngK protein FNZ59_RS03115 ENOG4105E5D amino acid FNZ59_RS03120 ENOG4105CVK Glutamate decarboxylase FNZ59_RS03125 ENOG4107RAN Peptidase, M16 FNZ59_RS03130 ENOG4105PE1 Receptor FNZ59_RS03135 ENOG4105CQ0 ABC transporter FNZ59_RS03145 ENOG4105C4X radical SAM domain protein FNZ59_RS03150 ENOG4105ENH Sulfatase FNZ59_RS03165 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit FNZ59_RS03170 ENOG4106PIH fimbrial-like protein ydeQ FNZ59_RS03175 ENOG4106318 fimbrial-like protein YdeR FNZ59_RS03180 ENOG4108WDE Fimbrial protein FNZ59_RS03210 ENOG4105CAF HipA N-terminal domain protein FNZ59_RS03215 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein FNZ59_RS03225 ENOG4107RYS Autoinducer-2 (AI-2) kinase FNZ59_RS03235 ENOG4105C2J ABC transporter FNZ59_RS03245 ENOG4105F5R ABC transporter FNZ59_RS03260 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound FNZ59_RS03270 ENOG4105FFC UPF0187 protein FNZ59_RS03280 ENOG4105BZU Histidine kinase FNZ59_RS03285 ENOG4105M0C cytoplasmic protein FNZ59_RS03290 ENOG4105CSV Glutaminase FNZ59_RS03295 ENOG4105C26 Dehydrogenase FNZ59_RS03300 ENOG4105EGI Transcriptional regulator FNZ59_RS03325 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FNZ59_RS03330 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF FNZ59_RS03335 ENOG4106DNR multiple antibiotic resistance protein FNZ59_RS03340 ENOG4105CS2 ec 3.2.1.21 FNZ59_RS03350 ENOG4105VCP PTS System FNZ59_RS03365 ENOG4105FDP GntR family transcriptional regulator FNZ59_RS03370 ENOG4108594 Permease of the drug metabolite transporter FNZ59_RS03385 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria FNZ59_RS03390 ENOG4108YDI single-species biofilm formation on inanimate substrate FNZ59_RS03395 ENOG4108WTK competence damage-inducible protein FNZ59_RS03400 ENOG4105DGW oligopeptidase A FNZ59_RS03405 ENOG4105EMU Dehydrogenase FNZ59_RS03410 ENOG4107XBN GntR Family Transcriptional Regulator FNZ59_RS03415 ENOG41061EV selenium-binding protein YdfZ FNZ59_RS03420 ENOG4105DEI Mannitol dehydrogenase FNZ59_RS03430 ENOG4105CXK mandelate racemase muconate lactonizing FNZ59_RS03445 ENOG4108MK9 spermidine N(1)-acetyltransferase FNZ59_RS03455 ENOG4105KBG Protein of unknown function (DUF1161) FNZ59_RS03465 ENOG4105C3J Cysteine desulfurase FNZ59_RS03470 ENOG4105QAX Iron-sulfur FNZ59_RS03475 ENOG4107KGK dmso reductase anchor subunit FNZ59_RS03480 ENOG4108NEM leader-binding protein dmsD FNZ59_RS03490 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FNZ59_RS03495 ENOG4105DAG ROK family FNZ59_RS03500 ENOG4106NZI LysR family Transcriptional regulator FNZ59_RS03505 ENOG4105D94 Major Facilitator Superfamily FNZ59_RS03520 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap FNZ59_RS03540 ENOG4105DSF transport protein FNZ59_RS03545 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FNZ59_RS03550 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FNZ59_RS03555 ENOG4105C5D exported protein FNZ59_RS03560 ENOG4105D5Q Arginine ornithine antiporter FNZ59_RS03570 ENOG4105RA2 Membrane FNZ59_RS03575 ENOG4107EXC regulatoR FNZ59_RS03580 ENOG4105JJR Histidine kinase FNZ59_RS03590 ENOG4105C9Q fumarate hydratase class II FNZ59_RS03595 ENOG4107GFK fumarate FNZ59_RS03600 ENOG4105EIP mannose-6-phosphate isomerase FNZ59_RS03605 ENOG4106J39 exported protein FNZ59_RS03610 ENOG4108QNI outer membrane porin protein FNZ59_RS03615 ENOG4105CT4 transporter FNZ59_RS03620 ENOG4105CNT hydrolase family 2 FNZ59_RS03625 ENOG4105XEA Tetr family transcriptional regulator FNZ59_RS03630 ENOG4107ZQV short-chain dehydrogenase reductase FNZ59_RS03635 ENOG4107P2S Transcriptional regulator FNZ59_RS03640 ENOG4105CI1 PTS System FNZ59_RS03645 ENOG4105C87 Aminotransferase class I and II FNZ59_RS03655 ENOG4105D9R oxidoreductase FNZ59_RS03660 ENOG4106C6R beta-lactam resistance protein FNZ59_RS03665 ENOG4105QZ5 OriC-binding nucleoid-associated protein FNZ59_RS03670 ENOG4105M9B inner membrane protein ydgK FNZ59_RS03695 ENOG4108UQQ Electron transport complex FNZ59_RS03705 ENOG4105CSM endonuclease III FNZ59_RS03710 ENOG4105DUX Transporter FNZ59_RS03715 ENOG4108K3A Glutathione S-transferase FNZ59_RS03720 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) FNZ59_RS03735 ENOG410642K Lysozyme inhibitor FNZ59_RS03745 ENOG4108XTF Outer Membrane Lipoprotein FNZ59_RS03760 ENOG4105Y49 secretion protein, HlyD family FNZ59_RS03765 ENOG4105DSW Fusaric acid resistance protein FNZ59_RS03770 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FNZ59_RS03775 ENOG4107RGM aldo keto reductase FNZ59_RS03780 ENOG4105XZD Fe-S protein FNZ59_RS03785 ENOG4108WUH Transcriptional regulator, TetR family FNZ59_RS03790 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FNZ59_RS03795 ENOG4108UYE Lactoylglutathione lyase FNZ59_RS03810 ENOG4105M2J Glutaredoxin FNZ59_RS03815 ENOG4105K4H Nlp p60 protein FNZ59_RS03820 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FNZ59_RS03825 ENOG4105F27 Major Facilitator FNZ59_RS03840 ENOG4105F52 Transcriptional regulator FNZ59_RS03845 ENOG4105CZQ inner membrane transport protein YdhC FNZ59_RS03850 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FNZ59_RS03855 ENOG4108R6K riboflavin synthase, subunit alpha FNZ59_RS03880 ENOG4105N0V mono-oxygenase ydhR FNZ59_RS03885 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain FNZ59_RS03890 ENOG4108Y7C Conserved Protein FNZ59_RS03895 ENOG4108NWD Cytochrome FNZ59_RS03900 ENOG4108393 oxidoreductase Fe-S subunit FNZ59_RS03905 ENOG4105JVW FNZ59_RS03910 ENOG4105WE2 aldehyde ferredoxin oxidoreductase FNZ59_RS03915 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein FNZ59_RS03920 ENOG4105RFR Protein of unknown function (DUF2767) FNZ59_RS03925 ENOG4105CA9 Pyruvate kinase FNZ59_RS03930 ENOG4105KMX major outer membrane lipoprotein FNZ59_RS03935 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FNZ59_RS03950 ENOG4105JRK feS assembly protein SufD FNZ59_RS03955 ENOG4105C3K feS assembly ATPase SufC FNZ59_RS03960 ENOG4105DIW FeS assembly protein SUFB FNZ59_RS03965 ENOG4108Z4V iron-sulfur cluster assembly FNZ59_RS03970 ENOG410671Z uncharacterized protein ydiH FNZ59_RS03975 ENOG4105KA0 thioesterase Superfamily protein FNZ59_RS03980 ENOG4105CQB FAD linked oxidase domain protein FNZ59_RS03985 ENOG4105IPI Membrane FNZ59_RS03995 ENOG4105SUA Ydil protein FNZ59_RS04000 ENOG4105EMV Major Facilitator FNZ59_RS04005 ENOG4105EMV Major Facilitator FNZ59_RS04020 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FNZ59_RS04025 ENOG4105C1G acyl-Coa dehydrogenase FNZ59_RS04030 ENOG4105W4W Transcriptional regulator FNZ59_RS04035 ENOG4105CV7 Electron transfer flavoprotein FNZ59_RS04040 ENOG4105C10 Electron transfer flavoprotein FNZ59_RS04045 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FNZ59_RS04050 ENOG41090P5 ferredoxin-like protein FNZ59_RS04055 ENOG4105CEY Amp-dependent synthetase and ligase FNZ59_RS04060 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FNZ59_RS04070 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FNZ59_RS04075 ENOG4106EDX Hemin uptake protein FNZ59_RS04080 ENOG4105CNG UPF0061 protein FNZ59_RS04085 ENOG4108TC0 Diguanylate phosphodiesterase FNZ59_RS04090 ENOG4108QBX (LipO)protein FNZ59_RS04100 ENOG4108V06 Glutathione peroxidase FNZ59_RS04115 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FNZ59_RS04130 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FNZ59_RS04135 ENOG41082NX 50s ribosomal protein l35 FNZ59_RS04160 ENOG4108NE3 Salt-induced outer membrane protein FNZ59_RS04165 ENOG4105DE4 1-phosphofructokinase FNZ59_RS04170 ENOG4105P10 Uncharacterized protein ydiZ FNZ59_RS04175 ENOG4105FGM Fructosamine kinase FNZ59_RS04180 ENOG4107PN8 YfeABCD locus regulator FNZ59_RS04185 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 FNZ59_RS04190 ENOG4107K5X Membrane-bound metal-dependent hydrolase FNZ59_RS04195 ENOG4108ETY sodium dicarboxylate symporter FNZ59_RS04210 ENOG4105CH6 catalase FNZ59_RS04220 ENOG4105F8D glycoside hydrolase family 4 FNZ59_RS04225 ENOG4105EZV Transcriptional regulator FNZ59_RS04230 ENOG4105VCP PTS System FNZ59_RS04235 ENOG4105CK1 PTS System FNZ59_RS04240 ENOG4105VZJ PTS System FNZ59_RS04245 ENOG4105KKI DNA-binding transcriptional activator OsmE FNZ59_RS04255 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) FNZ59_RS04265 ENOG4108SPG Periplasmic Protein FNZ59_RS04280 ENOG4105C26 Dehydrogenase FNZ59_RS04285 ENOG4105F4X arginine FNZ59_RS04295 ENOG4105CGK Exodeoxyribonuclease III FNZ59_RS04300 ENOG4108RSN SNARE associated Golgi FNZ59_RS04305 ENOG4108KCW iron-sulfur cluster binding FNZ59_RS04310 ENOG4108N5C SNARE associated Golgi protein-related protein FNZ59_RS04315 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FNZ59_RS04320 ENOG4105VNH ABC transporter solute-binding protein FNZ59_RS04325 ENOG4105CXZ ABC transporter, permease FNZ59_RS04330 ENOG4108VGW abc transporter atp-binding protein FNZ59_RS04335 ENOG4107RM6 sulfurtransferase FNZ59_RS04340 ENOG4108T9J Cdp-alcohol phosphatidyltransferase FNZ59_RS04345 ENOG4105M6F mutator MutT protein FNZ59_RS04350 ENOG4105MTM Protein of unknown function (DUF1496) FNZ59_RS04355 ENOG4105D82 Glutamate dehydrogenase FNZ59_RS04365 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FNZ59_RS04375 ENOG41069NU Nitroreductase FNZ59_RS04380 ENOG4105D07 Signal peptide peptidase, SppA FNZ59_RS04385 ENOG4105HDK L-asparaginase FNZ59_RS04390 ENOG4108RWI nicotinamidase FNZ59_RS04395 ENOG4108KUU Inner membrane metabolite transport protein ydjE FNZ59_RS04400 ENOG4105E98 transcriptional regulator DeoR family FNZ59_RS04405 ENOG4105CPC Aldo Keto reductase FNZ59_RS04410 ENOG4107UH8 sugar kinase FNZ59_RS04415 ENOG4105D2N Aldolase FNZ59_RS04425 ENOG4107TE1 transport protein FNZ59_RS04430 ENOG4105CPQ Dehydrogenase FNZ59_RS04435 ENOG4105VUT cytoplasmic protein FNZ59_RS04445 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FNZ59_RS04450 ENOG4105DSB aldose 1-epimerase FNZ59_RS04455 ENOG4105CV8 reductase FNZ59_RS04460 ENOG4105GNX MltA-interacting MipA family protein FNZ59_RS04465 ENOG4105CYN Serine protein kinase FNZ59_RS04475 ENOG4106KTS Inner membrane protein yeaI FNZ59_RS04480 ENOG4108KHP Diguanylate cyclase FNZ59_RS04485 ENOG4108KXH Ybak prolyl-tRNA synthetase associated FNZ59_RS04500 ENOG4105R1U AraC Family Transcriptional Regulator FNZ59_RS04505 ENOG4105DJ2 Major Facilitator Superfamily FNZ59_RS04510 ENOG4105K78 MarR family Transcriptional regulator FNZ59_RS04515 ENOG4105UCG Domain of unknown function (DUF333) FNZ59_RS04520 ENOG410620I Diguanylate cyclase FNZ59_RS04525 ENOG4106G4W FNZ59_RS04535 ENOG4105Y3U Transglycosylase-associated protein FNZ59_RS04540 ENOG4105YP6 Domain of unknown function (DUF1869) FNZ59_RS04545 ENOG4108YS1 cytoplasmic protein FNZ59_RS04555 ENOG4105EJC lysr family transcriptional regulator FNZ59_RS04560 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FNZ59_RS04565 ENOG4105C94 Transporter FNZ59_RS04570 ENOG4105DVW rieske (2Fe-2S) FNZ59_RS04575 ENOG4105E3J oxidoreductase FNZ59_RS04580 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FNZ59_RS04585 ENOG4105CEY Amp-dependent synthetase and ligase FNZ59_RS04590 ENOG4105Y4Z Outer Membrane Lipoprotein FNZ59_RS04595 ENOG41072GX Peptidase M22 Glycoprotease FNZ59_RS04600 ENOG4105DVT helicase FNZ59_RS04605 ENOG4105M4H endoribonuclease L-psp FNZ59_RS04615 ENOG4105V2F Uncharacterized protein yoac FNZ59_RS04625 ENOG4105CRQ synthase (Component I) FNZ59_RS04635 ENOG4105EJQ L-serine dehydratase FNZ59_RS04640 ENOG4107XTP (EAL) domain protein FNZ59_RS04645 ENOG4105EE5 Membrane protein terC FNZ59_RS04650 ENOG4108EQA pts system FNZ59_RS04655 ENOG4105ETZ PTS System FNZ59_RS04660 ENOG4105F3R pts system mannose fructose sorbose family iid FNZ59_RS04680 ENOG4105VEQ Cold shock protein FNZ59_RS04685 ENOG410610J Protein of unknown function (DUF2627) FNZ59_RS04690 ENOG4105Q3Y exported protein FNZ59_RS04700 ENOG4105TIK FNZ59_RS04705 ENOG4105J4Q Transcriptional regulator FNZ59_RS04710 ENOG4105C0R drug resistance transporter emrb qaca subfamily FNZ59_RS04720 ENOG4105CN1 protease FNZ59_RS04730 ENOG4108ZGC gaf domain protein FNZ59_RS04735 ENOG4105H2K paraquat-inducible protein a FNZ59_RS04740 ENOG4105DY2 Paraquat-inducible protein b FNZ59_RS04750 ENOG4105WT8 Protein of unknown function (DUF1480) FNZ59_RS04755 ENOG4105UVW uncharacterized protein yebW FNZ59_RS04760 ENOG4108R1E Serine threonine protein phosphatase 1 FNZ59_RS04765 ENOG4105NKT exported protein FNZ59_RS04770 ENOG4108PNC copper resistance FNZ59_RS04775 ENOG4105FXM Copper resistance protein FNZ59_RS04780 ENOG4105MPK DNA polymerase III subunit theta FNZ59_RS04785 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FNZ59_RS04790 ENOG4105UMD exodeoxyribonuclease X FNZ59_RS04795 ENOG4105CUG Oligopeptidase b FNZ59_RS04800 ENOG4108Q2J Inner membrane protein YebE FNZ59_RS04805 ENOG4105RSZ secreted protein FNZ59_RS04810 ENOG4105X2V dna damage-inducible protein FNZ59_RS04820 ENOG4108UHU Aldolase FNZ59_RS04825 ENOG4105C01 Dihydroxy-acid dehydratase FNZ59_RS04830 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FNZ59_RS04835 ENOG4106KNT transcriptional regulator FNZ59_RS04840 ENOG4105CA9 Pyruvate kinase FNZ59_RS04845 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase FNZ59_RS04850 ENOG4105DR5 peptidase FNZ59_RS04855 ENOG4105NXV High-affinity zinc uptake system protein FNZ59_RS04860 ENOG4105FDK ABC transporter FNZ59_RS04865 ENOG4105FAV ABC, transporter FNZ59_RS04880 ENOG4107S01 Repressor protein MetJ FNZ59_RS04890 ENOG4105CDY transcriptional regulatory protein FNZ59_RS04895 ENOG4108TIT dATP pyrophosphohydrolase FNZ59_RS04905 ENOG4105D3W isochorismatase FNZ59_RS04910 ENOG41081XQ Conserved Protein FNZ59_RS04915 ENOG4105WJG Glutathione FNZ59_RS04930 ENOG4107QY8 reductase FNZ59_RS04935 ENOG4105CUW cytochrome C-TYPE protein FNZ59_RS04945 ENOG4106ZCM YecM protein FNZ59_RS04960 ENOG4105W13 flagellar protein FNZ59_RS04965 ENOG4105D7B Flagellar biosynthesis protein flha FNZ59_RS04970 ENOG4105D00 flagellar biosynthetic protein flhB FNZ59_RS04975 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) FNZ59_RS04980 ENOG4108VYJ response regulator receiver protein FNZ59_RS04985 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FNZ59_RS04990 ENOG4105BZU Histidine kinase FNZ59_RS04995 ENOG4105C8Q Methyl-accepting chemotaxis FNZ59_RS05000 ENOG4105C8Q Methyl-accepting chemotaxis FNZ59_RS05005 ENOG4108V3W Chemotaxis protein, CheW FNZ59_RS05010 ENOG4105CBS Chea signal transduction histidine kinase FNZ59_RS05015 ENOG4105ER2 Ompa motb domain protein FNZ59_RS05020 ENOG4107RD7 Flagellar Motor Protein, MotA FNZ59_RS05025 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region FNZ59_RS05035 ENOG4108VA4 Universal stress protein FNZ59_RS05045 ENOG4108K4C ec 3.1.3.12 FNZ59_RS05050 ENOG4105CNN ABC, transporter FNZ59_RS05055 ENOG4105C2J ABC transporter FNZ59_RS05060 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator FNZ59_RS05065 ENOG4108UEC Ferritin-like protein FNZ59_RS05070 ENOG4105N4N Protein of unknown function (DUF2766) FNZ59_RS05080 ENOG4105P23 (LipO)protein FNZ59_RS05085 ENOG41090A1 ferritin FNZ59_RS05090 ENOG4105VVZ metal-binding protein FNZ59_RS05095 ENOG4105E0U tyrosine-specific transport protein FNZ59_RS05100 ENOG4106RHG Yeca family FNZ59_RS05120 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FNZ59_RS05130 ENOG4105WH1 Two component transcriptional regulator luxr family FNZ59_RS05140 ENOG4105XVG cytoplasmic protein FNZ59_RS05145 ENOG4105VJY transcriptional regulator FNZ59_RS05150 ENOG4105CDA abc transporter atp-binding protein FNZ59_RS05155 ENOG4105E5Q amino acid AbC transporter FNZ59_RS05165 ENOG4105EAB amino acid AbC transporter FNZ59_RS05170 ENOG4108M9K flagella biosynthesis protein FliZ FNZ59_RS05175 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FNZ59_RS05180 ENOG4105I03 Flagellin FNZ59_RS05185 ENOG4105DTS flagellar hook-associated FNZ59_RS05190 ENOG4105MQ3 flagellar protein FliS FNZ59_RS05200 ENOG4105E5K Alpha-amylase FNZ59_RS05205 ENOG4108W9D (LipO)protein FNZ59_RS05210 ENOG41066VF YeeE YedE family protein FNZ59_RS05215 ENOG4105KSU Redox protein FNZ59_RS05220 ENOG4108RAV Conserved protein FNZ59_RS05225 ENOG4105D7V transposase FNZ59_RS05235 ENOG4108UQN AraC family transcriptional regulator FNZ59_RS05240 ENOG4108V1U phospholipid-binding protein FNZ59_RS05245 ENOG410814C multidrug resistance protein FNZ59_RS05255 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) FNZ59_RS05260 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FNZ59_RS05265 ENOG41090PJ Flagellar assembly protein FNZ59_RS05270 ENOG4108JIR Flagellum-specific ATP synthase FNZ59_RS05275 ENOG4105GSA Flagellar export protein flij FNZ59_RS05280 ENOG4105WF4 Flagellar hook-length control protein FNZ59_RS05285 ENOG4107ZI8 flagellar basal body-associated protein flil FNZ59_RS05290 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FNZ59_RS05295 ENOG4105DD5 Flagellar motor switch protein FNZ59_RS05300 ENOG4105K0P flagellar biosynthesis protein FNZ59_RS05305 ENOG4105CN7 Flagellar biosynthetic protein FliP FNZ59_RS05310 ENOG4105VS8 Flagellar biosynthetic protein fliq FNZ59_RS05315 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FNZ59_RS05320 ENOG4107TKS colanic acid capsular biosynthesis activation protein A FNZ59_RS05330 ENOG4105YX3 cellular response to acidity FNZ59_RS05340 ENOG4105BZU Histidine kinase FNZ59_RS05345 ENOG4105VNZ cytoplasmic protein FNZ59_RS05350 ENOG4105CKW Inner membrane protein yedI FNZ59_RS05355 ENOG4105FDR Membrane FNZ59_RS05360 ENOG41090BB DNA mismatch endonuclease (vsr) FNZ59_RS05365 ENOG4105DVF Cytosine-specific methyltransferase FNZ59_RS05370 ENOG4105EST Metal Dependent Phosphohydrolase FNZ59_RS05375 ENOG4105Y0K Inner membrane protein YedR FNZ59_RS05380 ENOG4105ZIT Porin Gram-negative type FNZ59_RS05390 ENOG4107ZY3 Histidine kinase FNZ59_RS05395 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FNZ59_RS05400 ENOG4105VT2 5-hydroxyisourate hydrolase FNZ59_RS05415 ENOG4108MEK Metal-binding protein YodA FNZ59_RS05420 ENOG4108VKM cytochrome b561 FNZ59_RS05430 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) FNZ59_RS05450 ENOG4105TNG K13735 adhesin invasin FNZ59_RS05460 ENOG4105CSH Transporter FNZ59_RS05465 ENOG4105FYV Amp nucleosidase FNZ59_RS05470 ENOG4105CDY transcriptional regulatory protein FNZ59_RS05480 ENOG4105UQX Mate efflux family protein FNZ59_RS05490 ENOG4107R11 Transcriptional regulator FNZ59_RS05495 ENOG4106P55 Transcriptional regulator FNZ59_RS05505 ENOG4108PXI ErfK YbiS YcfS YnhG FNZ59_RS05520 ENOG4108YZT Adenosylcobinamide kinase FNZ59_RS05555 ENOG4108RVA ribokinase FNZ59_RS05570 ENOG41080QX K07048 phosphotriesterase-related protein FNZ59_RS05635 ENOG4108YIV FNZ59_RS05655 ENOG4106H6R UPF0380 protein FNZ59_RS05660 ENOG4105MFG Antirestriction protein FNZ59_RS05665 ENOG4108YGG dna repair protein FNZ59_RS05670 ENOG4106WJE Protein of unknown function (DUF987) FNZ59_RS05675 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FNZ59_RS05705 ENOG4105DR8 Membrane FNZ59_RS05710 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) FNZ59_RS05715 ENOG4105DZ1 carboxypeptidase FNZ59_RS05720 ENOG4105CJB Exodeoxyribonuclease I FNZ59_RS05730 ENOG4105CUC YeeE YedE family protein FNZ59_RS05735 ENOG4105CUB amino acid FNZ59_RS05745 ENOG4105EQ1 Transcriptional regulator FNZ59_RS05750 ENOG4108535 NAD dependent epimerase/dehydratase family FNZ59_RS05755 ENOG4105KRQ Addiction module toxin, Txe YoeB family FNZ59_RS05760 ENOG4105VTW prevent-host-death family FNZ59_RS05785 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FNZ59_RS05790 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FNZ59_RS05805 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FNZ59_RS05810 ENOG4105C6Y Udp-glucose 6-dehydrogenase FNZ59_RS05815 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FNZ59_RS05825 ENOG4105CKK Glycosyl transferase, family 2 FNZ59_RS05835 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FNZ59_RS05840 ENOG4108DMA Nad-dependent epimerase dehydratase FNZ59_RS05845 ENOG4105C0K Gdp-mannose 4,6-dehydratase FNZ59_RS05855 ENOG4108KQJ Type 11 methyltransferase FNZ59_RS05860 ENOG4105EY8 ABC transporter FNZ59_RS05880 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FNZ59_RS05895 ENOG4105EE5 Membrane protein terC FNZ59_RS05900 ENOG4108GAE asmA family FNZ59_RS05910 ENOG4105DBI uridine monophosphokinase FNZ59_RS05915 ENOG4105BZU Histidine kinase FNZ59_RS05920 ENOG4105D03 DNA-3-methyladenine glycosylase II FNZ59_RS05925 ENOG4105R8A Heat shock protein FNZ59_RS05930 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding FNZ59_RS05935 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase FNZ59_RS05940 ENOG4108M24 von Willebrand factor, type A FNZ59_RS05985 ENOG4105EB3 Histidine kinase FNZ59_RS05990 ENOG4105E3W Two component transcriptional regulator (Winged helix family FNZ59_RS05995 ENOG4105KWI UPF0339 protein FNZ59_RS06000 ENOG4105CFP Peptidase U32 FNZ59_RS06005 ENOG4105ZTC transcriptional activator, Ogr delta FNZ59_RS06045 ENOG4105ED4 portal protein FNZ59_RS06105 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FNZ59_RS06110 ENOG41076Z6 Uncharacterized protein yegR FNZ59_RS06125 ENOG4107WTH Galactitol-1-phosphate dehydrogenase FNZ59_RS06135 ENOG41090UW PTS System FNZ59_RS06140 ENOG41082GB PTS system galactitol-specific transporter subunit IIA FNZ59_RS06155 ENOG4105EIE fructose-bisphosphate aldolase FNZ59_RS06160 ENOG4105EAA nucleoside FNZ59_RS06165 ENOG4108KD5 ADP-ribosylation crystallin J1 FNZ59_RS06170 ENOG4108TFM Kinase, PfkB family FNZ59_RS06175 ENOG4105FDP GntR family transcriptional regulator FNZ59_RS06180 ENOG4108UQ1 hydrolase, family 25 FNZ59_RS06185 ENOG4105DWF phosphomethylpyrimidine kinase FNZ59_RS06205 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly FNZ59_RS06210 ENOG410662B Type-1 fimbrial protein FNZ59_RS06215 ENOG4105CW0 outer membrane usher protein FNZ59_RS06220 ENOG4108MQF Chaperone FNZ59_RS06225 ENOG41063W2 Fimbrial protein FNZ59_RS06230 ENOG41067AK Protein of unknown function (DUF2574) FNZ59_RS06235 ENOG4105D1F ATP-binding protein FNZ59_RS06245 ENOG4108KDT Molybdate metabolism regulator FNZ59_RS06250 ENOG4108KDT Molybdate metabolism regulator FNZ59_RS06260 ENOG4105KKX ATPase associated with various cellular activities aaa_5 FNZ59_RS06265 ENOG4105RD5 FNZ59_RS06270 ENOG4105DEG Vwa containing coxe family protein FNZ59_RS06275 ENOG410903U zinc ion binding FNZ59_RS06280 ENOG4108YCW (LipO)protein FNZ59_RS06285 ENOG4108W15 Protein of unknown function (DUF1456) FNZ59_RS06290 ENOG4108NEV two component transcriptional regulator, LytTR family FNZ59_RS06295 ENOG4108HRK Histidine kinase FNZ59_RS06300 ENOG4108XDN Transcriptional regulator FNZ59_RS06310 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component FNZ59_RS06315 ENOG4108IJ8 ABC transporter FNZ59_RS06320 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component FNZ59_RS06325 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system FNZ59_RS06330 ENOG4107QK4 glycoside hydrolase, family 3 domain protein FNZ59_RS06335 ENOG4105CXG d-lactate dehydrogenase FNZ59_RS06340 ENOG41061WM D-Alanyl-D-Alanine FNZ59_RS06345 ENOG41069YE inner membrane protein yohC FNZ59_RS06350 ENOG4105KHU inner membrane protein YohD FNZ59_RS06355 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FNZ59_RS06360 ENOG4105ETP RND efflux system, outer membrane lipoprotein FNZ59_RS06370 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FNZ59_RS06380 ENOG41067MG lrgb family FNZ59_RS06390 ENOG4107GZ4 SanA protein FNZ59_RS06395 ENOG4105Y9N Membrane FNZ59_RS06400 ENOG4105BZ8 glutamate synthase FNZ59_RS06405 ENOG4107SJI Dehydrogenase FNZ59_RS06410 ENOG4108HWV )-transporter FNZ59_RS06415 ENOG4105C2J ABC transporter FNZ59_RS06420 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FNZ59_RS06425 ENOG41060NJ transcriptional regulator FNZ59_RS06430 ENOG4105DHF Membrane FNZ59_RS06440 ENOG4105C4W S-formylglutathione hydrolase FNZ59_RS06445 ENOG4105D05 Receptor FNZ59_RS06450 ENOG4108IQI permease FNZ59_RS06455 ENOG4105DUM transcriptional regulator, lysR family FNZ59_RS06460 ENOG4105HMI Membrane FNZ59_RS06470 ENOG4105DD7 kinase (PfkB family FNZ59_RS06475 ENOG4105D9N nucleoside FNZ59_RS06485 ENOG4108Y4K DNA-binding transcriptional activator FNZ59_RS06490 ENOG4105D9N nucleoside FNZ59_RS06495 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) FNZ59_RS06500 ENOG4105DD7 kinase (PfkB family FNZ59_RS06505 ENOG4105DM4 PTS System FNZ59_RS06510 ENOG4105DE4 1-phosphofructokinase FNZ59_RS06515 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FNZ59_RS06520 ENOG4105S8Q sugar efflux transporter FNZ59_RS06525 ENOG4105KRS Proteinase inhibitor FNZ59_RS06535 ENOG4105DEI Mannitol dehydrogenase FNZ59_RS06540 ENOG4105CKI cobalamin synthesis protein FNZ59_RS06545 ENOG41076MN Phosphoesterase, PA-phosphatase related FNZ59_RS06550 ENOG4107TT5 NLP P60 protein FNZ59_RS06555 ENOG4105CXC rtn protein FNZ59_RS06560 ENOG4105E43 Extracellular solute-binding protein, family 5 FNZ59_RS06565 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FNZ59_RS06570 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FNZ59_RS06575 ENOG4108JQ5 ABC transporter FNZ59_RS06580 ENOG4105HG6 FNZ59_RS06585 ENOG4105C2C drug resistance transporter, Bcr CflA FNZ59_RS06590 ENOG4105I08 Pseudouridine synthase FNZ59_RS06595 ENOG4105CFI type iii restriction protein res subunit FNZ59_RS06615 ENOG4105E68 Sulfatase FNZ59_RS06630 ENOG4105WH1 Two component transcriptional regulator luxr family FNZ59_RS06635 ENOG4105KWW Biogenesis protein FNZ59_RS06640 ENOG4107QX9 Thiol disulfide interChange protein FNZ59_RS06645 ENOG4105DA4 cytochrome c-type biogenesis protein FNZ59_RS06655 ENOG4105X3C heme exporter protein FNZ59_RS06660 ENOG41060IM Heme exporter protein FNZ59_RS06665 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) FNZ59_RS06670 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) FNZ59_RS06675 ENOG4105CUW cytochrome C-TYPE protein FNZ59_RS06680 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) FNZ59_RS06685 ENOG4105GXZ Ferredoxin-type protein NapH FNZ59_RS06690 ENOG4108BGM Quinol dehydrogenase periplasmic component FNZ59_RS06700 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase FNZ59_RS06705 ENOG4108ZNS ferredoxin-type protein NapF FNZ59_RS06725 ENOG4105IBP Cyclic peptide transporter FNZ59_RS06730 ENOG4105CF1 Alkylated DNA repair protein FNZ59_RS06735 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FNZ59_RS06740 ENOG4105CJ2 (LipO)protein FNZ59_RS06745 ENOG4105FCK Membrane FNZ59_RS06750 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC FNZ59_RS06755 ENOG41068CG regulatoR FNZ59_RS06760 ENOG4105BZU Histidine kinase FNZ59_RS06765 ENOG4105BZU Histidine kinase FNZ59_RS06770 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FNZ59_RS06775 ENOG4107QP7 CoA-transferase subunit A FNZ59_RS06780 ENOG4107QNJ CoA-transferase subunit B FNZ59_RS06785 ENOG4105CRW Short chain fatty acid transporter FNZ59_RS06790 ENOG4105CHU acetyl-coa acetyltransferase FNZ59_RS06795 ENOG4105EDV vault protein FNZ59_RS06800 ENOG41081SK signal peptide protein FNZ59_RS06805 ENOG4107S52 alpha-2-macroglobulin domain protein FNZ59_RS06810 ENOG4108QJJ Protein of unknown function (DUF1175) FNZ59_RS06815 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) FNZ59_RS06820 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FNZ59_RS06835 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FNZ59_RS06840 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FNZ59_RS06845 ENOG4105XPH Ferredoxin FNZ59_RS06850 ENOG4105FQR PH-inducible protein involved in stress response FNZ59_RS06860 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FNZ59_RS06865 ENOG4105CXY transporter FNZ59_RS06870 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A FNZ59_RS06880 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FNZ59_RS06885 ENOG4105DNE Transposase FNZ59_RS06900 ENOG4105CSP Major Facilitator Superfamily FNZ59_RS06910 ENOG4107258 Transcriptional regulator FNZ59_RS06920 ENOG4108UII YfaZ family FNZ59_RS06950 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) FNZ59_RS06955 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) FNZ59_RS06965 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) FNZ59_RS06970 ENOG4106GZG polymyxin resistance protein B FNZ59_RS06975 ENOG4105CEY Amp-dependent synthetase and ligase FNZ59_RS06985 ENOG4108IPT Naphthoate synthase FNZ59_RS07000 ENOG4105E4F Isochorismate synthase FNZ59_RS07005 ENOG4105TNS Conserved Protein FNZ59_RS07010 ENOG4107YB6 acetyltransferase, (GNAT) family FNZ59_RS07020 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is FNZ59_RS07035 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FNZ59_RS07040 ENOG4105C8S subunit m FNZ59_RS07045 ENOG4105D65 subunit l FNZ59_RS07050 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FNZ59_RS07055 ENOG4107UFS subunit j FNZ59_RS07060 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FNZ59_RS07070 ENOG4107R0R NADH dehydrogenase subunit g FNZ59_RS07075 ENOG4107QIZ NADH dehydrogenase FNZ59_RS07080 ENOG4105GKE subunit e FNZ59_RS07085 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FNZ59_RS07100 ENOG4107NQ8 LysR family Transcriptional regulator FNZ59_RS07105 ENOG4105CHM Aminotransferase FNZ59_RS07115 ENOG4107QWE )-transporter FNZ59_RS07120 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 FNZ59_RS07135 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FNZ59_RS07140 ENOG4105C6K Malic enzyme FNZ59_RS07145 ENOG4105CSX c4-dicarboxylate anaerobic carrier FNZ59_RS07150 ENOG4105PTV Nudix Hydrolase FNZ59_RS07155 ENOG4108RE9 Phosphodiesterase FNZ59_RS07160 ENOG4108SHQ Glutathione S-transferase FNZ59_RS07165 ENOG4105CYM Glutathione S-transferase FNZ59_RS07170 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase FNZ59_RS07175 ENOG4105ECP epimerase FNZ59_RS07180 ENOG4105DNE Transposase FNZ59_RS07185 ENOG4108JEH abc transporter atp-binding protein FNZ59_RS07190 ENOG4106YG3 ABC transporter FNZ59_RS07195 ENOG4105DSP amino acid AbC transporter FNZ59_RS07200 ENOG4105E89 ABC transporter FNZ59_RS07205 ENOG4105E89 ABC transporter FNZ59_RS07210 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FNZ59_RS07215 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FNZ59_RS07220 ENOG4105E96 Colicin v production protein FNZ59_RS07225 ENOG4108S3P Sporulation domain protein FNZ59_RS07230 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FNZ59_RS07240 ENOG4105DQR SNARE associated Golgi FNZ59_RS07250 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FNZ59_RS07260 ENOG4106WZ1 flagella biosynthesis regulator FNZ59_RS07265 ENOG4105F9N Major Facilitator Superfamily FNZ59_RS07270 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FNZ59_RS07275 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) FNZ59_RS07280 ENOG4105MH2 YfcL protein FNZ59_RS07285 ENOG4108BPE -transporting atpase FNZ59_RS07290 ENOG4105EJ9 Membrane FNZ59_RS07295 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) FNZ59_RS07320 ENOG4105US4 fimbrial-like protein yfcP FNZ59_RS07325 ENOG4105UGQ Fimbrial FNZ59_RS07330 ENOG4105NEV Fimbrial FNZ59_RS07335 ENOG4108FZ9 Chaperone FNZ59_RS07340 ENOG4106PG1 outer membrane usher protein FNZ59_RS07350 ENOG4108BY2 phosphohistidine phosphatase FNZ59_RS07355 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FNZ59_RS07365 ENOG4105KZW UPF0381 protein FNZ59_RS07370 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation FNZ59_RS07380 ENOG410903C (LipO)protein FNZ59_RS07385 ENOG4105S64 Formate nitrite transporter FNZ59_RS07395 ENOG4105DFP Integrase FNZ59_RS07405 ENOG4105Y9F tail fiber protein FNZ59_RS07410 ENOG4105Y0G tail protein FNZ59_RS07415 ENOG4108T86 baseplate J family protein FNZ59_RS07435 ENOG4108NKR DNA circulation protein FNZ59_RS07460 ENOG4105TKZ Tail Sheath FNZ59_RS07495 ENOG4105CAR Terminase, large subunit FNZ59_RS07515 ENOG4106050 phage regulatory protein, rha family FNZ59_RS07520 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FNZ59_RS07550 ENOG4105RWQ Protein of unknown function (DUF1364) FNZ59_RS07610 ENOG4106G4W FNZ59_RS07655 ENOG4105VIZ double-strand break repair protein FNZ59_RS07660 ENOG4108UUM single-stranded DNA-binding protein FNZ59_RS07700 ENOG41065VV Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision FNZ59_RS07705 ENOG4105W8I Transcriptional regulator FNZ59_RS07710 ENOG4105C6Z Gluconate FNZ59_RS07720 ENOG4105C0R drug resistance transporter emrb qaca subfamily FNZ59_RS07725 ENOG4105CW7 secretion protein, HlyD family FNZ59_RS07730 ENOG4108WQH regulatoR FNZ59_RS07735 ENOG4105BZU Histidine kinase FNZ59_RS07740 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FNZ59_RS07745 ENOG4108N2Y auxin Efflux FNZ59_RS07750 ENOG4105CFN oxalyl-CoA decarboxylase FNZ59_RS07760 ENOG4108V08 YfdX protein FNZ59_RS07770 ENOG4105W9M Membrane FNZ59_RS07775 ENOG4105D1S lipid A biosynthesis FNZ59_RS07785 ENOG4105CHM Aminotransferase FNZ59_RS07790 ENOG4108HRK Histidine kinase FNZ59_RS07795 ENOG4105DY9 regulatoR FNZ59_RS07800 ENOG4108CIP transcriptional regulator FNZ59_RS07805 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FNZ59_RS07810 ENOG4105CN9 Peptidase m42 family protein FNZ59_RS07815 ENOG4105DC7 peptidase M24 FNZ59_RS07820 ENOG410863U PTS System FNZ59_RS07825 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) FNZ59_RS07835 ENOG4105VCT ion-transport protein YfeO FNZ59_RS07840 ENOG4109076 Conserved Protein FNZ59_RS07850 ENOG4105D9N nucleoside FNZ59_RS07855 ENOG4108KMM Diguanylate cyclase FNZ59_RS07870 ENOG4105HZG regulatoR FNZ59_RS07875 ENOG4105GXM Putative transcription regulator (DUF1323) FNZ59_RS07910 ENOG4105CN8 Transcriptional regulator FNZ59_RS07920 ENOG4105EAA nucleoside FNZ59_RS07925 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) FNZ59_RS07930 ENOG4108NFH Sugar hydrolase FNZ59_RS07935 ENOG4108M0I Transcriptional regulator FNZ59_RS07940 ENOG4105DHU Bile acid FNZ59_RS07945 ENOG4105VRT cytoplasmic protein FNZ59_RS07950 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FNZ59_RS07965 ENOG4105C6T cysteine synthase FNZ59_RS07970 ENOG4105KZ7 phosphocarrier protein hpr FNZ59_RS07975 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FNZ59_RS07980 ENOG4105C5Y PTS System FNZ59_RS07990 ENOG4105M0Y FNZ59_RS07995 ENOG4105C6T cysteine synthase FNZ59_RS08000 ENOG4108IJ6 ABC transporter FNZ59_RS08005 ENOG4105ECW sulfate abc transporter FNZ59_RS08010 ENOG4108I5D sulfate abc transporter FNZ59_RS08015 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein FNZ59_RS08020 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FNZ59_RS08030 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FNZ59_RS08035 ENOG4105C5Y PTS System FNZ59_RS08040 ENOG4107S1E Beta-lactamase FNZ59_RS08045 ENOG4105EZR dyp-type peroxidase family protein FNZ59_RS08050 ENOG4105E7K (LipO)protein FNZ59_RS08055 ENOG4105QZU Inner membrane protein YfeZ FNZ59_RS08060 ENOG4108R6G acetyltransferase FNZ59_RS08065 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase FNZ59_RS08075 ENOG4108K3Z AraC family transcriptional regulator FNZ59_RS08080 ENOG4108X49 Ethanolamine utilization protein EutK FNZ59_RS08085 ENOG4106D67 ethanolamine utilization protein FNZ59_RS08095 ENOG4105CPD ethanolamine ammonia-lyase FNZ59_RS08100 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase FNZ59_RS08105 ENOG4105ENY Ethanolamine utilization protein eutH FNZ59_RS08110 ENOG4105C0A alcohol dehydrogenase FNZ59_RS08115 ENOG4107RWI ethanolamine utilization protein eutJ FNZ59_RS08120 ENOG4108EKI Dehydrogenase FNZ59_RS08125 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml FNZ59_RS08130 ENOG4105KNY Microcompartments protein FNZ59_RS08135 ENOG4107WUY phosphate acetyltransferase FNZ59_RS08140 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase FNZ59_RS08145 ENOG4105NDK ethanolamine utilization protein FNZ59_RS08150 ENOG4106S4J ethanolamine utilization protein EutP FNZ59_RS08155 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place FNZ59_RS08160 ENOG4105C6K Malic enzyme FNZ59_RS08165 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FNZ59_RS08170 ENOG4105CV1 Transketolase (EC 2.2.1.1) FNZ59_RS08175 ENOG4108PVD exported protein FNZ59_RS08180 ENOG4107VIJ nudix hydrolase FNZ59_RS08185 ENOG4105BZ8 glutamate synthase FNZ59_RS08190 ENOG4105BZU Histidine kinase FNZ59_RS08195 ENOG4105BZS acriflavin resistance protein FNZ59_RS08205 ENOG4105KUZ arsenate reductase FNZ59_RS08220 ENOG4106KED esterase YpfH FNZ59_RS08230 ENOG4105CGZ zinc metallopeptidase FNZ59_RS08240 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FNZ59_RS08250 ENOG4105RH4 Glycine cleavage system transcriptional repressor FNZ59_RS08255 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FNZ59_RS08260 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FNZ59_RS08265 ENOG4108JPZ Monovalent cation H antiporter subunit D FNZ59_RS08275 ENOG4105D65 subunit l FNZ59_RS08280 ENOG4105D65 subunit l FNZ59_RS08285 ENOG4107WQX hydrogenase 4 membrane subunit FNZ59_RS08290 ENOG4108JPZ Monovalent cation H antiporter subunit D FNZ59_RS08295 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FNZ59_RS08305 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FNZ59_RS08310 ENOG4105I6X formate hydrogenlyase maturation FNZ59_RS08315 ENOG4108JUA Transcriptional regulator FNZ59_RS08320 ENOG4105TMB Formate nitrite transporter FNZ59_RS08325 ENOG4105C02 permease FNZ59_RS08330 ENOG4105ERG peptidase m48, ste24p FNZ59_RS08335 ENOG4105K89 arsenate reductase FNZ59_RS08345 ENOG4105C2W permease FNZ59_RS08360 ENOG4108V3E phosphoribosylglycinamide formyltransferase FNZ59_RS08365 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FNZ59_RS08370 ENOG4105C9X ppx gppa phosphatase FNZ59_RS08375 ENOG4105BZU Histidine kinase FNZ59_RS08380 ENOG41062G3 Protein of unknown function (DUF2633) FNZ59_RS08385 ENOG4108ZMA Outer membrane lipoprotein FNZ59_RS08390 ENOG41066DY Membrane FNZ59_RS08400 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FNZ59_RS08410 ENOG4105VPD cellular component movement FNZ59_RS08425 ENOG4105N21 Membrane FNZ59_RS08455 ENOG4108JQB penicillin-binding protein 1C FNZ59_RS08460 ENOG4105DN3 alpha-2-macroglobulin domain protein FNZ59_RS08465 ENOG4105KHC sulfurtransferase FNZ59_RS08470 ENOG4105YYA enhanced serine sensitivity protein SseB FNZ59_RS08480 ENOG4105WVQ Fe-S assembly protein IscX FNZ59_RS08485 ENOG4108ZIT Ferredoxin, 2FE-2S FNZ59_RS08505 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FNZ59_RS08530 ENOG4107XM9 (LipO)protein FNZ59_RS08535 ENOG4108MN2 Stationary phase inducible protein CsiE FNZ59_RS08540 ENOG4105D8G Major Facilitator superfamily FNZ59_RS08545 ENOG4108W5M transcriptional regulator FNZ59_RS08550 ENOG4105FUY alpha subunit FNZ59_RS08575 ENOG4108SB3 DoxX Family FNZ59_RS08580 ENOG4108ZKT aldose 1-epimerase FNZ59_RS08585 ENOG4105CPQ Dehydrogenase FNZ59_RS08590 ENOG4105CNN ABC, transporter FNZ59_RS08595 ENOG4108F37 ATP-binding component of a transport system FNZ59_RS08600 ENOG4105FCA ABC transporter periplasmic-binding protein YphF FNZ59_RS08605 ENOG4107HQ7 repeat protein FNZ59_RS08610 ENOG4108NZE NAGC-like transcriptional regulator FNZ59_RS08620 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FNZ59_RS08625 ENOG4108YZA Nitrogen regulatory protein pii FNZ59_RS08630 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FNZ59_RS08635 ENOG4108SKK alpha helix protein FNZ59_RS08640 ENOG4107WP9 Histidine kinase FNZ59_RS08655 ENOG4108Z6B deaminase FNZ59_RS08660 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB FNZ59_RS08665 ENOG4106G6Q Transcriptional regulator FNZ59_RS08670 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FNZ59_RS08685 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FNZ59_RS08705 ENOG4105C3F Signal peptidase i FNZ59_RS08715 ENOG4105WMJ Positive regulator of sigma E, RseC MucC FNZ59_RS08720 ENOG4105VQK sigma E regulatory protein, MucB RseB FNZ59_RS08725 ENOG41069PW sigma-e factor negative regulatory protein FNZ59_RS08730 ENOG4105EMN RNA polymerase sigma factor FNZ59_RS08740 ENOG4108IYU L-aspartate oxidase FNZ59_RS08745 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) FNZ59_RS08750 ENOG4105C1J atp-dependent rna helicase FNZ59_RS08755 ENOG41090KR LysR family transcriptional Regulator FNZ59_RS08775 ENOG4105EIB trna rrna methyltransferase FNZ59_RS08780 ENOG4105K63 Thioredoxin FNZ59_RS08785 ENOG4106IUH DTW domain containing protein FNZ59_RS08790 ENOG4105CD5 CoA-binding domain protein FNZ59_RS08795 ENOG4105JIM Phosphatidylserine synthase FNZ59_RS08800 ENOG4105T42 (LipO)protein FNZ59_RS08805 ENOG4105CSH Transporter FNZ59_RS08830 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FNZ59_RS08835 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FNZ59_RS08840 ENOG4105C34 Pseudouridine synthase FNZ59_RS08845 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FNZ59_RS08850 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA FNZ59_RS08865 ENOG4105YB8 TM2 domain containing protein FNZ59_RS08915 ENOG4108C33 Resolvase FNZ59_RS09025 ENOG4105ED4 portal protein FNZ59_RS09110 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FNZ59_RS09120 ENOG4105CQC Prephenate dehydratase FNZ59_RS09125 ENOG4105EHE chorismate mutase- prephenate dehydrogenase FNZ59_RS09130 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FNZ59_RS09135 ENOG4105QP9 Protein of unknown function (DUF2799) FNZ59_RS09140 ENOG4108WS1 FNZ59_RS09145 ENOG4108KHX Diguanylate cyclase FNZ59_RS09150 ENOG41090EK ompa motb domain protein FNZ59_RS09175 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FNZ59_RS09180 ENOG4106KVJ cytochrome C assembly protein FNZ59_RS09185 ENOG4108JU6 CBS domain protein FNZ59_RS09200 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FNZ59_RS09205 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FNZ59_RS09210 ENOG4105VDB UPF0125 protein FNZ59_RS09215 ENOG4108Z1B Cyclase dehydrase FNZ59_RS09230 ENOG4105DFP Integrase FNZ59_RS09240 ENOG4105FA0 parb-like partition protein FNZ59_RS09265 ENOG4105F9F transposase FNZ59_RS09275 ENOG4105E54 alpha-amylase FNZ59_RS09285 ENOG4105D5U fad dependent oxidoreductase FNZ59_RS09290 ENOG4105C26 Dehydrogenase FNZ59_RS09295 ENOG4108JPW Aminotransferase FNZ59_RS09300 ENOG4105C85 amino acid FNZ59_RS09305 ENOG4108PVQ transcriptional regulator FNZ59_RS09310 ENOG4109066 lysm domain bon superfamily protein FNZ59_RS09315 ENOG4105VPI YqaE family transport protein FNZ59_RS09320 ENOG41080HT Transcriptional regulator, arsr family FNZ59_RS09325 ENOG4108V62 Rhodanese domain protein FNZ59_RS09330 ENOG4108X73 DNA- binding protein FNZ59_RS09335 ENOG4108RNS Exports L-alanine (By similarity) FNZ59_RS09340 ENOG4108WMJ Protein of unknown function (DUF2002) FNZ59_RS09345 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) FNZ59_RS09350 ENOG4105WAZ (Glutaredoxin-like protein) NrdH FNZ59_RS09355 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FNZ59_RS09360 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FNZ59_RS09365 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FNZ59_RS09370 ENOG4108IJ7 Glycine betaine FNZ59_RS09375 ENOG4108HQS Glycine betaine FNZ59_RS09380 ENOG4105GIJ Glycine betaine FNZ59_RS09390 ENOG4108UMN azlc family FNZ59_RS09395 ENOG4105ZED uncharacterized protein ygaH FNZ59_RS09400 ENOG4105NTK Transcriptional repressor Mpra FNZ59_RS09405 ENOG4105CW7 secretion protein, HlyD family FNZ59_RS09410 ENOG4105C0R drug resistance transporter emrb qaca subfamily FNZ59_RS09425 ENOG4105W39 Membrane FNZ59_RS09430 ENOG4107VXZ Hydrolase FNZ59_RS09460 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FNZ59_RS09465 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FNZ59_RS09480 ENOG4107TH8 cina domain protein FNZ59_RS09485 ENOG4105CVE Lytic murein transglycosylase FNZ59_RS09490 ENOG410787A Pts system, glucitol sorbitol-specific FNZ59_RS09495 ENOG4105DZY Pts system, glucitol sorbitol-specific FNZ59_RS09500 ENOG4105VI0 Pts system, glucitol sorbitol-specific FNZ59_RS09505 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase FNZ59_RS09510 ENOG4105J92 DNA-binding transcriptional activator GutM FNZ59_RS09515 ENOG410804X Transcriptional regulator FNZ59_RS09520 ENOG4105C2X Arabinose 5-phosphate isomerase FNZ59_RS09540 ENOG4105C8H hydrogenase maturation protein Hypf FNZ59_RS09545 ENOG4108RC0 Electron transport protein FNZ59_RS09550 ENOG4105DDV Transcriptional regulator (LacI family FNZ59_RS09555 ENOG4105C5Y PTS System FNZ59_RS09560 ENOG4105CS2 ec 3.2.1.21 FNZ59_RS09565 ENOG4108MG9 hydrogenase 3 maturation protease FNZ59_RS09570 ENOG4105I6X formate hydrogenlyase maturation FNZ59_RS09575 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FNZ59_RS09580 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit FNZ59_RS09585 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FNZ59_RS09590 ENOG4107TDF Formate hydrogenlyase subunit 4 FNZ59_RS09595 ENOG4107R30 NADH dehydrogenase FNZ59_RS09600 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FNZ59_RS09605 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA FNZ59_RS09615 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FNZ59_RS09620 ENOG4107RSS Hydrogenase accessory protein HypB FNZ59_RS09625 ENOG41083WG hydrogenase assembly chaperone FNZ59_RS09630 ENOG4105CQS hydrogenase expression formation protein HypD FNZ59_RS09635 ENOG4105C45 hydrogenase expression formation protein (HypE) FNZ59_RS09640 ENOG4108JUA Transcriptional regulator FNZ59_RS09645 ENOG4105VXR cytoplasmic protein FNZ59_RS09660 ENOG4105MEW serine threonine protein phosphatase FNZ59_RS09665 ENOG4105MVE transcriptional regulator FNZ59_RS09670 ENOG4105ZXK Dehydrogenase FNZ59_RS09675 ENOG4105G63 Type III effector Hrp-dependent FNZ59_RS09680 ENOG4105FB2 class II Aldolase FNZ59_RS09685 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FNZ59_RS09690 ENOG4105C6Z Gluconate FNZ59_RS09695 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FNZ59_RS09700 ENOG4108K5P (LipO)protein FNZ59_RS09735 ENOG4105N0Z inner membrane protein ygbE FNZ59_RS09740 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FNZ59_RS09745 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) FNZ59_RS09755 ENOG4108MXK alkaline phosphatase isozyme conversion FNZ59_RS09760 ENOG4105PWE CRISPR-associated protein cas2 FNZ59_RS09765 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) FNZ59_RS09770 ENOG4108Y7V CRISPR-associated protein, Cse3 family FNZ59_RS09775 ENOG4108VWQ crispr-associated protein FNZ59_RS09785 ENOG4105F9F transposase FNZ59_RS09795 ENOG41061HK CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) FNZ59_RS09800 ENOG4105CYR Crispr-associated protein, cse1 family FNZ59_RS09805 ENOG4105DTT CRISPR-associated helicase, cas3 FNZ59_RS09830 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FNZ59_RS09835 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FNZ59_RS09840 ENOG4105WQV ferredoxin-like protein FNZ59_RS09845 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FNZ59_RS09850 ENOG4105YBM electron transfer flavoprotein subunit ygcQ FNZ59_RS09855 ENOG4106IKH Electron transfer flavoprotein FNZ59_RS09860 ENOG4105C54 Major Facilitator superfamily FNZ59_RS09865 ENOG4107R3A FAD linked oxidase domain protein FNZ59_RS09870 ENOG4105CHR reductase FNZ59_RS09875 ENOG4108ITV Inner membrane protein yqcE FNZ59_RS09880 ENOG4108CWB sugar kinase ygcE FNZ59_RS09885 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FNZ59_RS09895 ENOG4105HA9 of methanol dehydrogenase type FNZ59_RS09910 ENOG4105DXN mazG family FNZ59_RS09915 ENOG4105MZG transcriptional modulator of maze toxin, mazf FNZ59_RS09920 ENOG4106A2Z transcriptional regulator antitoxin, MazE FNZ59_RS09925 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FNZ59_RS09930 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FNZ59_RS09935 ENOG4105BZU Histidine kinase FNZ59_RS09940 ENOG4105EQX glucarate dehydratase FNZ59_RS09945 ENOG4105EQX glucarate dehydratase FNZ59_RS09950 ENOG4105DJB Major Facilitator Superfamily FNZ59_RS09955 ENOG4105QDK Flavodoxin FNZ59_RS09960 ENOG4105DR9 pseudouridine synthase FNZ59_RS09965 ENOG4105WP7 tRNA pseudouridine synthase C FNZ59_RS09980 ENOG4105EWT decarboxylase family FNZ59_RS09985 ENOG4105C44 Serine transporter FNZ59_RS09990 ENOG4105EJQ L-serine dehydratase FNZ59_RS10000 ENOG4105C0A alcohol dehydrogenase FNZ59_RS10005 ENOG4107W7X Aldolase FNZ59_RS10015 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FNZ59_RS10025 ENOG4105CNN ABC, transporter FNZ59_RS10030 ENOG4105C2J ABC transporter FNZ59_RS10040 ENOG4105CMG Carbohydrate kinase FNZ59_RS10050 ENOG4107EDW L-fucose operon activator FNZ59_RS10060 ENOG4105M08 Membrane FNZ59_RS10065 ENOG4105ETT transcriptional Regulator, LysR family FNZ59_RS10070 ENOG4105M5B (LipO)protein FNZ59_RS10075 ENOG4105C9B Cysteine desulfurase FNZ59_RS10080 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) FNZ59_RS10085 ENOG4105CUZ uba thif-type nad fad binding protein FNZ59_RS10090 ENOG4105CA3 membrane-bound lytic murein transglycosylase FNZ59_RS10110 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FNZ59_RS10115 ENOG4107QZM n-acetylglutamate synthase FNZ59_RS10120 ENOG4107QYX exodeoxyribonuclease v alpha FNZ59_RS10125 ENOG4107QKA exodeoxyribonuclease V beta FNZ59_RS10130 ENOG4107QXK peptidase FNZ59_RS10135 ENOG4105DSY exodeoxyribonuclease V, gamma FNZ59_RS10140 ENOG4105RVB Prepilin peptidase dependent protein c FNZ59_RS10145 ENOG4105SEN Protein of unknown function (DUF2509) FNZ59_RS10150 ENOG4105JCS prepilin peptidase dependent protein FNZ59_RS10155 ENOG4105IPU prepilin peptidase dependent protein A FNZ59_RS10170 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FNZ59_RS10185 ENOG4105EE5 Membrane protein terC FNZ59_RS10190 ENOG4105SUV lipoprotein YgdR FNZ59_RS10195 ENOG4105CPC Aldo Keto reductase FNZ59_RS10210 ENOG41060NJ transcriptional regulator FNZ59_RS10215 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FNZ59_RS10220 ENOG4105RQF LysR family Transcriptional regulator FNZ59_RS10230 ENOG4107QNK )-transporter FNZ59_RS10235 ENOG4105CHR reductase FNZ59_RS10245 ENOG4105CHU acetyl-coa acetyltransferase FNZ59_RS10250 ENOG4108MHD transport protein FNZ59_RS10255 ENOG4105ISV protein with bipartite regulator domain FNZ59_RS10260 ENOG4108TC1 Transcriptional regulator FNZ59_RS10265 ENOG4105FV3 FNZ59_RS10290 ENOG4108YAB Invasion protein FNZ59_RS10325 ENOG4108RBT type iii secretion FNZ59_RS10330 ENOG4106BTR FNZ59_RS10335 ENOG4105Y7Q type iii secretion FNZ59_RS10340 ENOG4108RC9 Type III secretion system protein FNZ59_RS10355 ENOG4108M6W surface presentation of antigens protein SpaS FNZ59_RS10365 ENOG4108TN6 type iii secretion FNZ59_RS10375 ENOG41075IY surface presentation of antigens protein SpaP FNZ59_RS10385 ENOG4108T88 FNZ59_RS10495 ENOG4108K5P (LipO)protein FNZ59_RS10500 ENOG4105C7W Xanthine dehydrogenase FNZ59_RS10505 ENOG4108HR6 Dehydrogenase FNZ59_RS10510 ENOG4108UTP (2Fe-2S)-binding domain protein FNZ59_RS10515 ENOG4108JUB Transcriptional regulator FNZ59_RS10520 ENOG4105IW6 Carbamoyltransferase FNZ59_RS10525 ENOG4107RCH Diaminopropionate ammonia-lyase FNZ59_RS10530 ENOG4107S4Y M20 DapE family protein YgeY FNZ59_RS10540 ENOG4105C5B carbamate kinase FNZ59_RS10545 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FNZ59_RS10550 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC FNZ59_RS10555 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase FNZ59_RS10560 ENOG4105BZ8 glutamate synthase FNZ59_RS10565 ENOG4107UUR Chlorohydrolase aminohydrolase FNZ59_RS10570 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase FNZ59_RS10575 ENOG4105C7W Xanthine dehydrogenase FNZ59_RS10580 ENOG4105C2W permease FNZ59_RS10585 ENOG4107QUY Guanine deaminase FNZ59_RS10590 ENOG4105C7N Xanthine uracil vitamin C permease FNZ59_RS10595 ENOG4108R8B oxidoreductase Fe-S subunit FNZ59_RS10600 ENOG4105BZ8 glutamate synthase FNZ59_RS10605 ENOG4105C2W permease FNZ59_RS10625 ENOG4105CRK lysyL-tRNA synthetase FNZ59_RS10635 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FNZ59_RS10640 ENOG4105T95 Thiol disulfide interChange protein FNZ59_RS10645 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FNZ59_RS10650 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) FNZ59_RS10655 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB FNZ59_RS10660 ENOG4105Y75 tpr repeat protein FNZ59_RS10670 ENOG4108UT2 hemolysin iii FNZ59_RS10680 ENOG4105CS2 ec 3.2.1.21 FNZ59_RS10685 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FNZ59_RS10710 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FNZ59_RS10715 ENOG4105D0A hydroxylase FNZ59_RS10720 ENOG4107RAQ aminopeptidase FNZ59_RS10740 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FNZ59_RS10750 ENOG4108JQ1 Dehydrogenase FNZ59_RS10770 ENOG4105D5P Methylmalonyl-coA mutase FNZ59_RS10775 ENOG4105DJT lAO AO transport system ATPase FNZ59_RS10780 ENOG4108M7F enoyl-CoA hydratase isomerase FNZ59_RS10785 ENOG4105CYC Transferase FNZ59_RS10790 ENOG4105DEQ transcriptional regulator FNZ59_RS10795 ENOG4105MPN Membrane FNZ59_RS10800 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FNZ59_RS10805 ENOG4105D64 Mechanosensitive ion channel FNZ59_RS10810 ENOG4105D2N Aldolase FNZ59_RS10825 ENOG4107Z1W Fructose transport system kinase FNZ59_RS10830 ENOG4108R4K DNA-binding, transcriptional regulator FNZ59_RS10835 ENOG4108Q8A Fructose-1,6-bisphosphatase FNZ59_RS10840 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FNZ59_RS10850 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia FNZ59_RS10855 ENOG4105CV1 Transketolase (EC 2.2.1.1) FNZ59_RS10860 ENOG4108K0D peptidase, M48 FNZ59_RS10870 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) FNZ59_RS10890 ENOG4107QNK )-transporter FNZ59_RS10900 ENOG4105RWS endonuclease I FNZ59_RS10905 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FNZ59_RS10910 ENOG4105D7Z glutathione synthase FNZ59_RS10925 ENOG4105CZX twitching motility protein FNZ59_RS10930 ENOG4105DFA alanine racemase domain protein FNZ59_RS10935 ENOG4108VIA integral membrane protein FNZ59_RS10945 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FNZ59_RS10950 ENOG4105CSA Coproporphyrinogen iii oxidase FNZ59_RS10955 ENOG4106MH3 alpha helix chain FNZ59_RS10960 ENOG4105HDK L-asparaginase FNZ59_RS10965 ENOG4105K33 Periplasmic Protein FNZ59_RS10970 ENOG41090ED Protein with unknown function (DUF469) FNZ59_RS10980 ENOG4105CEN a g-specific adenine glycosylase FNZ59_RS10995 ENOG4105EAA nucleoside FNZ59_RS11000 ENOG4105CXN decarboxylase FNZ59_RS11005 ENOG4108UQV Membrane FNZ59_RS11050 ENOG4106P2F Pfam:Pili_assembly_C FNZ59_RS11055 ENOG4106PG1 outer membrane usher protein FNZ59_RS11060 ENOG4108ZJG MrfB protein FNZ59_RS11065 ENOG4105HMV Fimbrial protein FNZ59_RS11110 ENOG4105KF5 hemolysin expression-modulating protein FNZ59_RS11145 ENOG4108EU4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FNZ59_RS11160 ENOG4105F4K antigen 43 FNZ59_RS11170 ENOG4106H6R UPF0380 protein FNZ59_RS11175 ENOG4106549 Antirestriction protein FNZ59_RS11180 ENOG4108YGG dna repair protein FNZ59_RS11185 ENOG4106WJE Protein of unknown function (DUF987) FNZ59_RS11190 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FNZ59_RS11215 ENOG4105U1E general secretion pathway protein M FNZ59_RS11235 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) FNZ59_RS11240 ENOG4105F88 accessory colonization factor AcfD FNZ59_RS11245 ENOG4105DAA L-lactate FNZ59_RS11250 ENOG4107QP3 malate synthase g FNZ59_RS11255 ENOG4108ZJF Glcg protein FNZ59_RS11260 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FNZ59_RS11265 ENOG4105EU8 FAD linked oxidase domain protein FNZ59_RS11270 ENOG4105CQB FAD linked oxidase domain protein FNZ59_RS11275 ENOG4108KWP DNA-binding transcriptional regulator GlcC FNZ59_RS11285 ENOG4107RCI amp-dependent synthetase and ligase FNZ59_RS11295 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FNZ59_RS11300 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FNZ59_RS11310 ENOG4108M8S permease YjgP YjgQ family protein FNZ59_RS11315 ENOG4108UUE Transcriptional regulator FNZ59_RS11325 ENOG4108S55 polysaccharide biosynthesis protein FNZ59_RS11330 ENOG4106FPV ATP-binding protein YghR FNZ59_RS11335 ENOG4108NDC ATP-binding protein yghS FNZ59_RS11340 ENOG4108GH0 ATP-binding protein yghT FNZ59_RS11350 ENOG4106032 Glutathionylspermidine synthase FNZ59_RS11355 ENOG4105CYM Glutathione S-transferase FNZ59_RS11360 ENOG41082MF Hydrogenase assembly chaperone hypC hupF FNZ59_RS11365 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FNZ59_RS11370 ENOG4108WGS hydrogenase 2-specific chaperone FNZ59_RS11375 ENOG4108USZ hydrogenase FNZ59_RS11380 ENOG4105DPX Hydrogenase, large subunit FNZ59_RS11385 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit FNZ59_RS11390 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FNZ59_RS11395 ENOG4105E3S small subunit FNZ59_RS11415 ENOG4105CPC Aldo Keto reductase FNZ59_RS11425 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FNZ59_RS11430 ENOG4108ZZF transport protein (ExbD) FNZ59_RS11435 ENOG4105CWK Biopolymer transport protein, ExbB FNZ59_RS11440 ENOG4105C28 cystathionine FNZ59_RS11445 ENOG4108K81 inner membrane protein YghB FNZ59_RS11450 ENOG4105CF7 AraC family transcriptional regulator FNZ59_RS11455 ENOG4108I6A alcohol dehydrogenase FNZ59_RS11460 ENOG4105CV8 reductase FNZ59_RS11465 ENOG4105ZKC Conserved Protein FNZ59_RS11475 ENOG4105CCT upf0313 protein FNZ59_RS11480 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) FNZ59_RS11485 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase FNZ59_RS11490 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FNZ59_RS11500 ENOG4105WJ3 XRE family Transcriptional regulator FNZ59_RS11505 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation FNZ59_RS11510 ENOG4105F4I Transcriptional regulator FNZ59_RS11515 ENOG4105H4F exported protein FNZ59_RS11520 ENOG4105XJC Two component transcriptional regulator (Winged helix family FNZ59_RS11525 ENOG4105DHQ Histidine kinase FNZ59_RS11530 ENOG4107DEU Inner membrane protein YgiZ FNZ59_RS11535 ENOG4105NF4 modulator of drug activity FNZ59_RS11540 ENOG4105VRH Antibiotic biosynthesis monooxygenase FNZ59_RS11545 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FNZ59_RS11550 ENOG4105IPS esterase FNZ59_RS11555 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FNZ59_RS11560 ENOG4108SX3 cytoplasmic protein FNZ59_RS11565 ENOG41087AY ADP-Ribose pyrophosphatase FNZ59_RS11570 ENOG4105DFG type I secretion outer membrane protein FNZ59_RS11580 ENOG4106032 Glutathionylspermidine synthase FNZ59_RS11585 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FNZ59_RS11605 ENOG4105W0Z cytoplasmic protein FNZ59_RS11610 ENOG4105H8W Fimbrial protein FNZ59_RS11620 ENOG4108TTM chaperone FNZ59_RS11625 ENOG4108MY7 Fimbrial FNZ59_RS11635 ENOG4105PV3 Inner membrane protein yqiJ FNZ59_RS11640 ENOG4107S78 Band 7 protein FNZ59_RS11665 ENOG4105I7R Adenylate cyclase FNZ59_RS11670 ENOG4106MWK domain protein FNZ59_RS11680 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FNZ59_RS11685 ENOG4107ZVW dihydroneopterin aldolase FNZ59_RS11695 ENOG4105EJC lysr family transcriptional regulator FNZ59_RS11700 ENOG4106DSS Tartrate dehydratase subunit alpha FNZ59_RS11705 ENOG4107GFK fumarate FNZ59_RS11710 ENOG4107QPK )-transporter FNZ59_RS11720 ENOG4105VCC 30S ribosomal protein S21 FNZ59_RS11725 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FNZ59_RS11730 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FNZ59_RS11745 ENOG4105Q26 Siderophore-interacting protein FNZ59_RS11750 ENOG4105NTW Transcriptional regulator FNZ59_RS11755 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor FNZ59_RS11765 ENOG4108Y51 tRNA-binding protein FNZ59_RS11770 ENOG4105CQ4 Transcriptional regulator FNZ59_RS11775 ENOG4105CNT hydrolase family 2 FNZ59_RS11780 ENOG4105FK9 beta-D-galactosidase beta subunit FNZ59_RS11785 ENOG4105E5D amino acid FNZ59_RS11790 ENOG4107W6W Conserved Protein FNZ59_RS11795 ENOG4107WCA isomerase FNZ59_RS11800 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FNZ59_RS11805 ENOG4108Z3N Transcriptional regulator FNZ59_RS11810 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase FNZ59_RS11815 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) FNZ59_RS11820 ENOG4108VKG metal-dependent hydrolase FNZ59_RS11825 ENOG4108UB4 uncharacterized protein ygjQ FNZ59_RS11830 ENOG4105EE0 oxidoreductase FNZ59_RS11835 ENOG4105DU1 integral membrane protein, terc FNZ59_RS11840 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) FNZ59_RS11845 ENOG4105P66 Membrane FNZ59_RS11850 ENOG4105CTX dehydratase FNZ59_RS11860 ENOG4105DPW Major facilitator superfamily MFS_1 FNZ59_RS11865 ENOG4107YCY Transcriptional regulator FNZ59_RS11870 ENOG4106W5V Membrane FNZ59_RS11875 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) FNZ59_RS11880 ENOG4105WAY exported protein FNZ59_RS11885 ENOG4105NE1 Conserved Protein FNZ59_RS11890 ENOG41090KG Inner membrane protein YqjE FNZ59_RS11895 ENOG4105YJD FNZ59_RS11900 ENOG4108VBZ doxx family FNZ59_RS11905 ENOG4105CHF Glutathione S-transferase FNZ59_RS11910 ENOG4105KAF membrAne FNZ59_RS11915 ENOG4105KAF membrAne FNZ59_RS11920 ENOG4105CWB LysR family transcriptional Regulator FNZ59_RS11925 ENOG4108CNN domain protein FNZ59_RS11930 ENOG4106D80 Uncharacterized protein YhaL FNZ59_RS11940 ENOG4105C44 Serine transporter FNZ59_RS11945 ENOG4105EJQ L-serine dehydratase FNZ59_RS11950 ENOG4105KME endoribonuclease L-psp FNZ59_RS11955 ENOG4105C6N Formate acetyltransferase FNZ59_RS11960 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FNZ59_RS11970 ENOG4105C7B Threonine dehydratase FNZ59_RS11975 ENOG410811B TRANSCRIPTIONal FNZ59_RS12000 ENOG4105BZW Glycerate kinase FNZ59_RS12005 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FNZ59_RS12015 ENOG4105DJB Major Facilitator Superfamily FNZ59_RS12020 ENOG4105CTX dehydratase FNZ59_RS12025 ENOG4105ZEG Suppressor protein FNZ59_RS12030 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression FNZ59_RS12035 ENOG4105E98 transcriptional regulator DeoR family FNZ59_RS12045 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB FNZ59_RS12060 ENOG4108YTN IIa component FNZ59_RS12065 ENOG4105CE4 GlcNAc 6-P deacetylase FNZ59_RS12070 ENOG4105E70 isomerase FNZ59_RS12080 ENOG4108UZY PTS System FNZ59_RS12085 ENOG4105ETZ PTS System FNZ59_RS12090 ENOG4105F3R pts system mannose fructose sorbose family iid FNZ59_RS12095 ENOG4106HBN Galactosamine-6-phosphate isomerase FNZ59_RS12100 ENOG4105Q10 Fimbrial-like protein FNZ59_RS12105 ENOG4108VCD Chaperone FNZ59_RS12110 ENOG4105CW0 outer membrane usher protein FNZ59_RS12115 ENOG4105I74 Fimbrial protein FNZ59_RS12120 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FNZ59_RS12125 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) FNZ59_RS12135 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) FNZ59_RS12140 ENOG4105W4M Transport-associated protein FNZ59_RS12145 ENOG4107S21 permease FNZ59_RS12150 ENOG4105K4T epimerase FNZ59_RS12155 ENOG4107R7Y intracellular protease Pfpi family FNZ59_RS12170 ENOG4108YYD acetyltransferase FNZ59_RS12175 ENOG4105XPQ lipid carrier protein FNZ59_RS12180 ENOG4105CFP Peptidase U32 FNZ59_RS12185 ENOG4106RZ4 Peptidase U32 FNZ59_RS12190 ENOG4105DEN Luciferase family FNZ59_RS12195 ENOG4105CIC tryptophan-specific transport protein FNZ59_RS12200 ENOG4105C1J atp-dependent rna helicase FNZ59_RS12210 ENOG4105RT1 May be involved in cell division (By similarity) FNZ59_RS12225 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FNZ59_RS12240 ENOG4105CHV Transcription elongation factor NusA FNZ59_RS12260 ENOG4105DIJ Phosphoethanolamine transferase FNZ59_RS12280 ENOG4105EEI dihydropteroate synthase FNZ59_RS12285 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FNZ59_RS12290 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) FNZ59_RS12295 ENOG4105HBR Rna-binding protein FNZ59_RS12300 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FNZ59_RS12305 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase FNZ59_RS12315 ENOG4105QYV Membrane FNZ59_RS12330 ENOG4105EAH synthase FNZ59_RS12335 ENOG4105HVQ Regulatory factor of maltose metabolism FNZ59_RS12345 ENOG4105VFK BolA family FNZ59_RS12350 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane FNZ59_RS12355 ENOG4105E3I toluene tolerance FNZ59_RS12360 ENOG4107PE3 Mammalian cell entry related domain protein FNZ59_RS12365 ENOG4105CY3 ABC transporter, permease FNZ59_RS12370 ENOG4105DHJ ABC, transporter FNZ59_RS12375 ENOG4105FEU K -dependent Na -Ca exchanger FNZ59_RS12380 ENOG4105C2X Arabinose 5-phosphate isomerase FNZ59_RS12390 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) FNZ59_RS12395 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FNZ59_RS12400 ENOG4108IUZ ABC transporter FNZ59_RS12405 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FNZ59_RS12410 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA FNZ59_RS12415 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN FNZ59_RS12425 ENOG41080Z8 PHOSPHOCARRIER protein FNZ59_RS12430 ENOG4108NIH transferase activity, transferring phosphorus-containing groups FNZ59_RS12435 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase FNZ59_RS12440 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain FNZ59_RS12445 ENOG4105BZU Histidine kinase FNZ59_RS12450 ENOG4105N5T Radical SAM Protein FNZ59_RS12455 ENOG4105CBC glutamate synthase FNZ59_RS12460 ENOG4105BZ8 glutamate synthase FNZ59_RS12465 ENOG4105DFS Conserved Protein FNZ59_RS12475 ENOG4108R66 Conserved Protein FNZ59_RS12480 ENOG41061DF Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity) FNZ59_RS12505 ENOG4105CEE C4-dicarboxylate transporter FNZ59_RS12510 ENOG4105KB2 stringent starvation protein b FNZ59_RS12515 ENOG4107MKT Stringent starvation protein a FNZ59_RS12520 ENOG4108UJD 30S ribosomal protein S9 FNZ59_RS12530 ENOG4105D6Z AFG1 family ATPase FNZ59_RS12535 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III FNZ59_RS12540 ENOG4105C0H protease FNZ59_RS12545 ENOG4105C0H protease FNZ59_RS12560 ENOG4105RID UPF0379 protein yhcN FNZ59_RS12565 ENOG4105UNR (Barnase) inhibitor FNZ59_RS12585 ENOG4105CR8 Transcriptional regulator FNZ59_RS12590 ENOG4105D1U peptidase U62 modulator of DNA gyrase FNZ59_RS12595 ENOG4105QD6 exported protein FNZ59_RS12600 ENOG4105C03 ribonuclease FNZ59_RS12610 ENOG4105VQ7 Rod shape-determining protein MreD FNZ59_RS12615 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FNZ59_RS12620 ENOG4105DFF Rod shape-determining protein mreb FNZ59_RS12625 ENOG41062P1 Diguanylate cyclase phosphodiesterase FNZ59_RS12630 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family FNZ59_RS12640 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FNZ59_RS12645 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FNZ59_RS12650 ENOG4105RG0 Membrane FNZ59_RS12655 ENOG4108IA2 Sodium pantothenate symporter FNZ59_RS12665 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FNZ59_RS12670 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) FNZ59_RS12680 ENOG4105CAR Terminase, large subunit FNZ59_RS12780 ENOG4105DFP Integrase FNZ59_RS12785 ENOG4105CEC DNA methylase N-4 N-6 FNZ59_RS12790 ENOG41061ME transport protein FNZ59_RS12795 ENOG4108XG4 DNA-binding transcriptional regulator FNZ59_RS12800 ENOG4105C1P efflux transporter, rnd family, mfp subunit FNZ59_RS12805 ENOG4105BZS acriflavin resistance protein FNZ59_RS12810 ENOG4105XCM membrane LIPOPROTEIN FNZ59_RS12820 ENOG4105EZ7 amino acid ABC transporter FNZ59_RS12825 ENOG4105DRP amino acid AbC transporter FNZ59_RS12830 ENOG4105CDA abc transporter atp-binding protein FNZ59_RS12870 ENOG4108Z0R Transferase FNZ59_RS12875 ENOG4105SG3 Protein of unknown function (DUF1488) FNZ59_RS12885 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FNZ59_RS12890 ENOG4108WI1 Dna topoisomerase FNZ59_RS12900 ENOG4105C79 DNA protecting protein DprA FNZ59_RS12920 ENOG4105C1A potassium transporter peripheral membrane FNZ59_RS12930 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system FNZ59_RS12935 ENOG4105W1Y Transcriptional regulator FNZ59_RS12940 ENOG4105VTS DnaJ-like, subfamily C FNZ59_RS12950 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FNZ59_RS12955 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FNZ59_RS12965 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FNZ59_RS12970 ENOG41067V7 50S ribosomal protein L36 FNZ59_RS12975 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FNZ59_RS12990 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FNZ59_RS12995 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FNZ59_RS13005 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FNZ59_RS13020 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FNZ59_RS13030 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FNZ59_RS13040 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FNZ59_RS13045 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FNZ59_RS13050 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FNZ59_RS13055 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FNZ59_RS13065 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FNZ59_RS13070 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FNZ59_RS13085 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication FNZ59_RS13090 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression FNZ59_RS13095 ENOG4107KSE General secretion pathway protein C FNZ59_RS13100 ENOG4105GVR general secretion pathway protein D FNZ59_RS13110 ENOG4105D7Q type ii secretion system FNZ59_RS13115 ENOG4108VAU general secretion pathway protein G FNZ59_RS13120 ENOG41069X0 general secretion pathway protein h FNZ59_RS13135 ENOG4105R04 type II secretion system protein K FNZ59_RS13140 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) FNZ59_RS13150 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) FNZ59_RS13155 ENOG4108UQY Iron-storage protein FNZ59_RS13160 ENOG4105W53 bacterioferritin-associated ferredoxin FNZ59_RS13165 ENOG4108NNZ chitinase FNZ59_RS13205 ENOG4105WWK YheO domain protein FNZ59_RS13210 ENOG4108V1T peptidylprolyl cis-trans isomerase FNZ59_RS13220 ENOG4108YZY peptidylprolyl cis-trans isomerase FNZ59_RS13225 ENOG4105VKU nucleicacid-binding protein FNZ59_RS13240 ENOG4105C5H ABC transporter FNZ59_RS13245 ENOG4105DNZ Alpha Beta Hydrolase FNZ59_RS13255 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) FNZ59_RS13260 ENOG4108UKZ OsmC family FNZ59_RS13265 ENOG4107RYR Transcriptional regulator, Crp Fnr family FNZ59_RS13270 ENOG410613R integral membrane protein, YccS YhfK family FNZ59_RS13275 ENOG4105C8Y Acetylornithine aminotransferase FNZ59_RS13280 ENOG4105DDQ anthranilate synthase FNZ59_RS13285 ENOG4105MZU cell filamentation protein FNZ59_RS13290 ENOG4106195 uncharacterized protein yhfG FNZ59_RS13295 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FNZ59_RS13305 ENOG4107QZF nitrite reductase NADPH large subunit FNZ59_RS13310 ENOG4105WZK nitrite reductase NADPH small subunit FNZ59_RS13315 ENOG4107V9H nitrite transporter FNZ59_RS13325 ENOG4105VYH FNZ59_RS13330 ENOG4107QHQ amino acid FNZ59_RS13335 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine FNZ59_RS13340 ENOG4107Y0V Not clear, may be involved in an isomerization step FNZ59_RS13345 ENOG4108KPW sugar kinase FNZ59_RS13350 ENOG4105FDP GntR family transcriptional regulator FNZ59_RS13355 ENOG4106PKC pyridoxal phosphate binding FNZ59_RS13360 ENOG4106M0N transport system permease protein FNZ59_RS13365 ENOG4105MUZ Protein of unknown function DUF2620 FNZ59_RS13370 ENOG41080QX K07048 phosphotriesterase-related protein FNZ59_RS13375 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FNZ59_RS13380 ENOG4108626 Racemase FNZ59_RS13385 ENOG4105RMW regulation of transcription, DNA-dependent FNZ59_RS13390 ENOG4108M21 FNZ59_RS13395 ENOG4105C31 Tryptophanyl-tRNA synthetase FNZ59_RS13400 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FNZ59_RS13405 ENOG4105DJV ribulose-phosphate 3-epimerase FNZ59_RS13410 ENOG4105DFE Dna adenine methylase FNZ59_RS13415 ENOG4105EGB membrane protein DamX FNZ59_RS13430 ENOG4105E4G Type IV pilus FNZ59_RS13435 ENOG4105ITY Required for the use of extracellular DNA as a nutrient FNZ59_RS13440 ENOG4105XPX DNA utilization protein HofO FNZ59_RS13445 ENOG41065NF Fimbrial assembly family protein FNZ59_RS13450 ENOG4108U1Q Pilus assembly protein FNZ59_RS13455 ENOG4108JQC penicillin-binding protein 1A FNZ59_RS13460 ENOG4107RK2 ADP-ribose diphosphatase NudE FNZ59_RS13465 ENOG4105DQY intracellular growth attenuator FNZ59_RS13470 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FNZ59_RS13475 ENOG4105VEJ Heat shock protein FNZ59_RS13485 ENOG4108MAJ Membrane FNZ59_RS13495 ENOG4105E0F Histidine kinase FNZ59_RS13500 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FNZ59_RS13505 ENOG4108RRZ Transcription elongation factor GreB FNZ59_RS13510 ENOG4105BZM domain protein FNZ59_RS13515 ENOG4105XFK Ferrous iron transport protein A FNZ59_RS13520 ENOG4105CE1 Ferrous iron transport protein b FNZ59_RS13530 ENOG4105DNE Transposase FNZ59_RS13540 ENOG4105MJ2 Competence protein FNZ59_RS13550 ENOG4105C6Z Gluconate FNZ59_RS13555 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) FNZ59_RS13560 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FNZ59_RS13575 ENOG4105E0Y RtcB Protein FNZ59_RS13580 ENOG4105CYB regulatoR FNZ59_RS13585 ENOG4105E98 transcriptional regulator DeoR family FNZ59_RS13600 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FNZ59_RS13620 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FNZ59_RS13635 ENOG4108IUM Glycogen debranching enzyme FNZ59_RS13645 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FNZ59_RS13650 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FNZ59_RS13655 ENOG4105C6Z Gluconate FNZ59_RS13660 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FNZ59_RS13665 ENOG4105DIQ Transcriptional regulator FNZ59_RS13675 ENOG4105C2I pirin domain protein FNZ59_RS13680 ENOG4105D9R oxidoreductase FNZ59_RS13685 ENOG4105WCN acetyltransferase FNZ59_RS13690 ENOG4105GMB type VI secretion system effector, hcp1 family FNZ59_RS13705 ENOG4106FA4 FNZ59_RS13710 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FNZ59_RS13715 ENOG4105WC8 Conserved Protein FNZ59_RS13720 ENOG4107T6V glycerophosphoryl diester phosphodiesterase FNZ59_RS13725 ENOG4108IJ9 (ABC) transporter FNZ59_RS13730 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FNZ59_RS13735 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component FNZ59_RS13740 ENOG4105BZ7 extracellular solute-binding protein family 1 FNZ59_RS13745 ENOG4108IV0 ABC, transporter FNZ59_RS13750 ENOG4105C0Z ABC transporter FNZ59_RS13755 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FNZ59_RS13760 ENOG4105C32 Amino acid ABC transporter (Permease) FNZ59_RS13765 ENOG4105CP9 extracellular ligand-binding receptor FNZ59_RS13770 ENOG4105U59 -acetyltransferase FNZ59_RS13775 ENOG4105CP9 extracellular ligand-binding receptor FNZ59_RS13780 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FNZ59_RS13785 ENOG4105CRP Part of the ABC transporter FtsEX involved in FNZ59_RS13790 ENOG4105CAK Cell division ATP-binding protein ftsE FNZ59_RS13795 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FNZ59_RS13800 ENOG4106H78 methyltransferase FNZ59_RS13805 ENOG4105MG3 Membrane FNZ59_RS13815 ENOG4107FS9 Membrane FNZ59_RS13830 ENOG4105EX9 Membrane FNZ59_RS13835 ENOG4108W1V Lipoprotein FNZ59_RS13840 ENOG4105F9N Major Facilitator Superfamily FNZ59_RS13845 ENOG4105DSF transport protein FNZ59_RS13850 ENOG4107YAK holo-(acyl carrier protein) synthase 2 FNZ59_RS13855 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FNZ59_RS13860 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FNZ59_RS13865 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FNZ59_RS13870 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) FNZ59_RS13885 ENOG4105CNA YD repeat protein FNZ59_RS13895 ENOG4105NUP lyase containing HEAT-repeat FNZ59_RS13905 ENOG4105CMI transporter FNZ59_RS13910 ENOG4105CJ1 ABC, transporter FNZ59_RS13915 ENOG4105D0S secretion protein (HlyD FNZ59_RS13930 ENOG4107UNS conserved inner membrane protein FNZ59_RS13935 ENOG4105CBX hi0933 family FNZ59_RS13940 ENOG4105CJ3 phosphate transporter FNZ59_RS13950 ENOG4108M6U Universal stress protein A FNZ59_RS13955 ENOG4105DUX Transporter FNZ59_RS13960 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) FNZ59_RS13965 ENOG4105DGW oligopeptidase A FNZ59_RS13970 ENOG4105D6S protein involved in catabolism of external DNA FNZ59_RS13975 ENOG4105DC8 reductase FNZ59_RS13985 ENOG4105KBH arsR family transcriptional regulator FNZ59_RS13990 ENOG4107R5R arsenical pump membrane protein FNZ59_RS13995 ENOG4105K89 arsenate reductase FNZ59_RS14005 ENOG4105Y4Z Outer Membrane Lipoprotein FNZ59_RS14015 ENOG4105KT7 mgtC SapB transporter FNZ59_RS14020 ENOG4105XXV Acid-resistance protein FNZ59_RS14025 ENOG41060V2 Acid-resistance protein FNZ59_RS14030 ENOG4108YK4 Acid-resistance membrane protein FNZ59_RS14035 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci FNZ59_RS14045 ENOG4105C1P efflux transporter, rnd family, mfp subunit FNZ59_RS14050 ENOG4105BZS acriflavin resistance protein FNZ59_RS14055 ENOG4105D3F AraC Family Transcriptional Regulator FNZ59_RS14060 ENOG4108NKV transcriptional regulator FNZ59_RS14065 ENOG4105CVK Glutamate decarboxylase FNZ59_RS14070 ENOG4105CA0 peroxidase FNZ59_RS14080 ENOG4106S2D Transcriptional regulator FNZ59_RS14085 ENOG4105CBN LysR family transcriptional regulator FNZ59_RS14090 ENOG4107H3J ribonuclease FNZ59_RS14095 ENOG4105CSH Transporter FNZ59_RS14100 ENOG41066T0 asmA family FNZ59_RS14105 ENOG4105CMB EAL domain-containing protein FNZ59_RS14115 ENOG4105CS0 peptidase FNZ59_RS14125 ENOG4105BZU Histidine kinase FNZ59_RS14130 ENOG4105EJG cellulose synthase FNZ59_RS14135 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) FNZ59_RS14140 ENOG4107EEX Cellulose synthase regulator protein FNZ59_RS14145 ENOG4107QZ7 Cellulose synthase catalytic subunit FNZ59_RS14155 ENOG410661M cytoplasmic protein FNZ59_RS14160 ENOG4105U74 cellulose biosynthesis protein BcsE FNZ59_RS14165 ENOG4105WQA Cellulose biosynthesis protein BcsF FNZ59_RS14190 ENOG4105C44 Serine transporter FNZ59_RS14195 ENOG4108JQ7 (ABC) transporter FNZ59_RS14200 ENOG4105C3U ABC transporter FNZ59_RS14205 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FNZ59_RS14210 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FNZ59_RS14215 ENOG4105DEF Extracellular solute-binding protein, family 5 FNZ59_RS14230 ENOG4105DIJ Phosphoethanolamine transferase FNZ59_RS14235 ENOG4105FCD Major Facilitator FNZ59_RS14240 ENOG4105EAX Putative lipase FNZ59_RS14245 ENOG4108R3E Dna-3-methyladenine glycosylase i FNZ59_RS14250 ENOG4105HNP -acetyltransferase FNZ59_RS14255 ENOG4107QY8 reductase FNZ59_RS14260 ENOG4108ZG0 Ompa motb domain protein FNZ59_RS14270 ENOG4106JH6 (LipO)protein FNZ59_RS14275 ENOG4105MVF Transcriptional regulator FNZ59_RS14280 ENOG4105VEQ Cold shock protein FNZ59_RS14285 ENOG41060TC Hok gef cell toxic protein FNZ59_RS14300 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit FNZ59_RS14310 ENOG4105MEV Acyl-transferase FNZ59_RS14315 ENOG4108Z12 YiaAB two helix domain-containing protein FNZ59_RS14320 ENOG410688U Inner membrane protein yiaB FNZ59_RS14325 ENOG4105CMG Carbohydrate kinase FNZ59_RS14335 ENOG4105DFW ABC transporter FNZ59_RS14340 ENOG4105C2J ABC transporter FNZ59_RS14345 ENOG4107RNG ABC transporter FNZ59_RS14350 ENOG4105T16 Transcriptional regulator (AraC family) FNZ59_RS14355 ENOG4108UR8 BAX protein FNZ59_RS14360 ENOG4107T9C Alpha amylase catalytic region FNZ59_RS14365 ENOG4105JKW Valine--pyruvate aminotransferase FNZ59_RS14370 ENOG4108XIB electron transport protein ysaA FNZ59_RS14375 ENOG4105J4Q Transcriptional regulator FNZ59_RS14385 ENOG4108R66 Conserved Protein FNZ59_RS14390 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter FNZ59_RS14395 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FNZ59_RS14400 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FNZ59_RS14405 ENOG4105CMG Carbohydrate kinase FNZ59_RS14410 ENOG4105H6Q decarboxylase FNZ59_RS14415 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase FNZ59_RS14420 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FNZ59_RS14430 ENOG4105GNX MltA-interacting MipA family protein FNZ59_RS14435 ENOG4108Q2M Transcriptional regulator FNZ59_RS14440 ENOG4105EFX secretion protein, HlyD family FNZ59_RS14445 ENOG4105KK7 inner membrane protein YiaW FNZ59_RS14455 ENOG4105C26 Dehydrogenase FNZ59_RS14460 ENOG4105C0A alcohol dehydrogenase FNZ59_RS14465 ENOG4105EM7 Selenocysteine-specific translation elongation factor FNZ59_RS14475 ENOG4108U78 Glutathione S-transferase FNZ59_RS14480 ENOG4105CNA YD repeat protein FNZ59_RS14495 ENOG4105EFX secretion protein, HlyD family FNZ59_RS14500 ENOG4105FP6 Protein of unknown function (DUF3302) FNZ59_RS14505 ENOG4105CTS PTS system mannitol-specific FNZ59_RS14515 ENOG4105E61 Mannitol repressor protein FNZ59_RS14525 ENOG4108YYI Protein of unknown function (DUF2810) FNZ59_RS14530 ENOG4105DAA L-lactate FNZ59_RS14535 ENOG41073TP transcriptional regulator FNZ59_RS14545 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FNZ59_RS14550 ENOG4105D7W serine acetyltransferase FNZ59_RS14565 ENOG4105VW4 glutaredoxin 3 FNZ59_RS14570 ENOG4107YZP Rhodanese domain protein FNZ59_RS14580 ENOG41063SB peptidase FNZ59_RS14585 ENOG4105PXI polysaccharide deacetylase FNZ59_RS14590 ENOG4105K64 Glycosyl transferase, family 2 FNZ59_RS14600 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FNZ59_RS14610 ENOG4105XA0 heptosyltransferase ii FNZ59_RS14615 ENOG4105D16 lipopolysaccharide heptosyltransferase i FNZ59_RS14620 ENOG4108FRV O-antigen ligase FNZ59_RS14625 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase FNZ59_RS14630 ENOG4108QD8 lipopolysaccharide core biosynthesis protein FNZ59_RS14635 ENOG4108PDR lipopolysaccharide core biosynthesis protein FNZ59_RS14640 ENOG4105X1N Glycosyl transferase family 8 FNZ59_RS14645 ENOG4106AH0 Glycosyl Transferase FNZ59_RS14650 ENOG4107XU6 Glycosyl transferase (Group 1 FNZ59_RS14655 ENOG4105X1N Glycosyl transferase family 8 FNZ59_RS14660 ENOG4107543 (lipo)polysaccharide FNZ59_RS14665 ENOG4107RJ7 Glycosyl transferase (Group 1 FNZ59_RS14670 ENOG4105DKP glycosyl transferase, family 9 FNZ59_RS14675 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FNZ59_RS14690 ENOG4105W0E 50S ribosomal protein L33 FNZ59_RS14705 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FNZ59_RS14730 ENOG4105DSJ YicC domain protein FNZ59_RS14735 ENOG4105F5P DNA-damage-inducible protein d FNZ59_RS14740 ENOG4105EN6 Membrane FNZ59_RS14745 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) FNZ59_RS14750 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FNZ59_RS14755 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) FNZ59_RS14760 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FNZ59_RS14765 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase FNZ59_RS14770 ENOG4105CB5 ATP-dependent DNA helicase recG FNZ59_RS14775 ENOG4105D6U Sodium Glutamate Symporter FNZ59_RS14780 ENOG4105C2W permease FNZ59_RS14785 ENOG4105JV1 AsmA family FNZ59_RS14790 ENOG4105CJQ hydrolase, family 31 FNZ59_RS14810 ENOG4105S8Q sugar efflux transporter FNZ59_RS14815 ENOG4108UZ3 Transporter FNZ59_RS14820 ENOG4105D01 (LipO)protein FNZ59_RS14825 ENOG4105T8A Uncharacterized protein YicS FNZ59_RS14835 ENOG4108SAJ Protein of unknown function (DUF1198) FNZ59_RS14840 ENOG4105C7N Xanthine uracil vitamin C permease FNZ59_RS14850 ENOG4105CXY transporter FNZ59_RS14855 ENOG4105CXY transporter FNZ59_RS14860 ENOG4105BZU Histidine kinase FNZ59_RS14865 ENOG4108KX4 response regulator FNZ59_RS14870 ENOG4105M71 acetolactate synthase 1 regulatory subunit FNZ59_RS14875 ENOG4105C7K acetolactate synthase FNZ59_RS14890 ENOG4105E5M Multidrug resistance protein D FNZ59_RS14895 ENOG4105J13 transcriptional regulator FNZ59_RS14900 ENOG4105JP4 Inner membrane protein yidG FNZ59_RS14905 ENOG4105VG5 Membrane FNZ59_RS14910 ENOG4106DRA Inner membrane protein YidI FNZ59_RS14915 ENOG4105CBG Sulfatase FNZ59_RS14920 ENOG4107RUZ Sss sodium solute transporter superfamily FNZ59_RS14925 ENOG4108AHD Transcriptional regulator FNZ59_RS14935 ENOG4105CI1 PTS System FNZ59_RS14940 ENOG4105FDP GntR family transcriptional regulator FNZ59_RS14960 ENOG4105R2A (LipO)protein FNZ59_RS14965 ENOG4105D99 atp gtp-binding protein FNZ59_RS14970 ENOG4107WAP fad NAD(P)-binding domain FNZ59_RS14975 ENOG4105DJB Major Facilitator Superfamily FNZ59_RS14985 ENOG4108RTU Aldolase FNZ59_RS14990 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 FNZ59_RS14995 ENOG4105EMF GntR family transcriptional regulator FNZ59_RS15000 ENOG410657R replicase EC 2.7 FNZ59_RS15005 ENOG410667J hydrolase FNZ59_RS15010 ENOG4105VP5 Bacterial protein of unknown function (DUF937) FNZ59_RS15015 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FNZ59_RS15025 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FNZ59_RS15075 ENOG4108P6C Tryptophan transporter of low affinity FNZ59_RS15090 ENOG4105E8Q phosphopantetheinyl transferase FNZ59_RS15095 ENOG4108YYH Nadph-dependent fmn reductase FNZ59_RS15100 ENOG4105C7N Xanthine uracil vitamin C permease FNZ59_RS15105 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 FNZ59_RS15115 ENOG4106611 bacteriocin immunity FNZ59_RS15120 ENOG4107VKM 6-phosphogluconolactonase FNZ59_RS15125 ENOG4105DYC esterase FNZ59_RS15135 ENOG4105CS2 ec 3.2.1.21 FNZ59_RS15145 ENOG4105CID antiterminator FNZ59_RS15150 ENOG4108UTW Plays a role in the regulation of phosphate uptake FNZ59_RS15155 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FNZ59_RS15160 ENOG4105E2Z phosphate ABC transporter (Permease FNZ59_RS15165 ENOG4105C8U phosphate abc transporter FNZ59_RS15170 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) FNZ59_RS15175 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FNZ59_RS15215 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FNZ59_RS15225 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation FNZ59_RS15240 ENOG4105QTB Flavodoxin FNZ59_RS15245 ENOG4108VVK transcriptional Regulator, AsnC FNZ59_RS15255 ENOG4105EV2 VWA domain protein interacting with AAA ATPase FNZ59_RS15270 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) FNZ59_RS15275 ENOG4105C2J ABC transporter FNZ59_RS15280 ENOG4105CNN ABC, transporter FNZ59_RS15285 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FNZ59_RS15290 ENOG4108RVA ribokinase FNZ59_RS15295 ENOG4105ETE Transcriptional regulator (LacI family FNZ59_RS15300 ENOG4105C0R drug resistance transporter emrb qaca subfamily FNZ59_RS15305 ENOG4107EJG GntR family transcriptional regulator FNZ59_RS15345 ENOG4108WFC UPF0438 protein yifE FNZ59_RS15350 ENOG4105C0P Mg chelatase subunit ChlI FNZ59_RS15370 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit FNZ59_RS15375 ENOG4105CM2 brancheD-chain amino acid aminotransferase FNZ59_RS15385 ENOG4105C7B Threonine dehydratase FNZ59_RS15390 ENOG4105EMY transcriptional regulator FNZ59_RS15400 ENOG4105KQ5 peptidylprolyl cis-trans isomerase FNZ59_RS15410 ENOG4105C4R Atp-dependent dna helicase FNZ59_RS15425 ENOG4105K63 Thioredoxin FNZ59_RS15440 ENOG4105ESV Glycosyl transferase, family 4 FNZ59_RS15445 ENOG4105SFE lipopolysaccharide biosynthesis protein FNZ59_RS15450 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FNZ59_RS15455 ENOG4108IJ1 Dehydrogenase FNZ59_RS15460 ENOG4105C1B dTDP-glucose 4-6-dehydratase FNZ59_RS15465 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FNZ59_RS15470 ENOG4108WJ1 acetyltransferase FNZ59_RS15475 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FNZ59_RS15480 ENOG4105EGZ biosynthesis protein FNZ59_RS15485 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) FNZ59_RS15500 ENOG4105C85 amino acid FNZ59_RS15525 ENOG4105C4X radical SAM domain protein FNZ59_RS15530 ENOG4105ENH Sulfatase FNZ59_RS15535 ENOG410601J HemY protein FNZ59_RS15540 ENOG4105ECF c-methyltransferase FNZ59_RS15545 ENOG41076E6 Uroporphyrinogen-III Synthase FNZ59_RS15555 ENOG4107T0K Adenylate cyclase FNZ59_RS15565 ENOG4105S7Z (LipO)protein FNZ59_RS15575 ENOG4105CT0 Protein of unknown function, DUF484 FNZ59_RS15585 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant FNZ59_RS15590 ENOG4105C4R Atp-dependent dna helicase FNZ59_RS15595 ENOG4108T58 Mg2 transport protein CorA FNZ59_RS15600 ENOG4107QUT magnesium and cobalt transport protein CorA FNZ59_RS15605 ENOG4105NRM Membrane FNZ59_RS15615 ENOG4105FR1 rard protein FNZ59_RS15620 ENOG4108VUY thioesterase Superfamily protein FNZ59_RS15625 ENOG4105HDD phospholipase FNZ59_RS15630 ENOG4105C9U ATP-dependent DNA helicase RecQ FNZ59_RS15645 ENOG4108EUD Lysophospholipase FNZ59_RS15650 ENOG4105DQF Hydrolase FNZ59_RS15655 ENOG4105EMK carboxylate amino acid amine transporter FNZ59_RS15660 ENOG4105DZ2 Transcriptional regulator FNZ59_RS15665 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) FNZ59_RS15670 ENOG4105F52 Transcriptional regulator FNZ59_RS15675 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin FNZ59_RS15685 ENOG4105C5B carbamate kinase FNZ59_RS15690 ENOG4107REC cytoplasmic protein FNZ59_RS15695 ENOG4107R1Q Membrane protein FdrA FNZ59_RS15705 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) FNZ59_RS15710 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) FNZ59_RS15715 ENOG4108I5U Uridine phosphorylase FNZ59_RS15730 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FNZ59_RS15740 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 FNZ59_RS15745 ENOG4107HP6 Transcriptional regulator FNZ59_RS15750 ENOG4105CGY Dna recombination protein FNZ59_RS15760 ENOG4105JC1 sterol-binding domain protein FNZ59_RS15770 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FNZ59_RS15775 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) FNZ59_RS15780 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FNZ59_RS15790 ENOG4105MDZ Transcriptional activator rfaH FNZ59_RS15795 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FNZ59_RS15800 ENOG4107QK7 reductase FNZ59_RS15820 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FNZ59_RS15825 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FNZ59_RS15830 ENOG4108RR8 protoporphyrinogen oxidase FNZ59_RS15860 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b FNZ59_RS15865 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FNZ59_RS15870 ENOG4105PC1 Conserved Protein FNZ59_RS15875 ENOG4105E27 serine threonine protein kinase FNZ59_RS15880 ENOG4108Z33 Thiol disulfide Interchange Protein FNZ59_RS15890 ENOG4106HNH Acyl-transferase FNZ59_RS15900 ENOG4105C2M dna polymerase I FNZ59_RS15910 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) FNZ59_RS15915 ENOG4105D4P Coproporphyrinogen iii oxidase FNZ59_RS15920 ENOG4106FIY FNZ59_RS15925 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FNZ59_RS15930 ENOG4105CUX Signal transduction histidine kinase FNZ59_RS15935 ENOG4105C5F glutamine synthetase FNZ59_RS15945 ENOG4108K85 Transcriptional regulator FNZ59_RS15950 ENOG4108KHF Resistance protein FNZ59_RS15960 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is FNZ59_RS15965 ENOG4105CT4 transporter FNZ59_RS15970 ENOG4105CT4 transporter FNZ59_RS15975 ENOG4105CJQ hydrolase, family 31 FNZ59_RS15985 ENOG4107WI4 Aldose-1-epimerase FNZ59_RS15990 ENOG4107QKS N-acylglucosamine 2-epimerase FNZ59_RS15995 ENOG4105D2M Aldolase FNZ59_RS16000 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FNZ59_RS16005 ENOG4108MGF sugar kinase FNZ59_RS16010 ENOG4105E98 transcriptional regulator DeoR family FNZ59_RS16015 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 FNZ59_RS16030 ENOG4105SUU thioesterase domain FNZ59_RS16035 ENOG4106UEE Transcriptional regulator FNZ59_RS16040 ENOG41068KX affects formate dehydrogenase-N FNZ59_RS16050 ENOG4108MG3 formate dehydrogenase FNZ59_RS16055 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FNZ59_RS16070 ENOG4108V87 frv operon regulatory protein FNZ59_RS16075 ENOG4106C3V frv operon regulatory protein FNZ59_RS16080 ENOG4105CN9 Peptidase m42 family protein FNZ59_RS16085 ENOG4105DM4 PTS System FNZ59_RS16090 ENOG41064BA PTS system, fructose-specific, IIA component FNZ59_RS16115 ENOG4105DET Rhamnulokinase FNZ59_RS16135 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FNZ59_RS16145 ENOG4108RPX mosc domain containing protein FNZ59_RS16150 ENOG4105E0F Histidine kinase FNZ59_RS16155 ENOG4105E3W Two component transcriptional regulator (Winged helix family FNZ59_RS16160 ENOG4105FMW periplasmic FNZ59_RS16175 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FNZ59_RS16190 ENOG4105EBK exported protein FNZ59_RS16195 ENOG4108VTS Membrane FNZ59_RS16200 ENOG41065TG regulatoR FNZ59_RS16210 ENOG4105DP0 ferredoxin-NADP reductase FNZ59_RS16215 ENOG4105CBT Fructose-1,6-bisphosphatase FNZ59_RS16225 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FNZ59_RS16240 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FNZ59_RS16245 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) FNZ59_RS16255 ENOG41063M6 Cell Division Protein FNZ59_RS16260 ENOG4105ETE Transcriptional regulator (LacI family FNZ59_RS16265 ENOG4105C25 Primosomal protein n' FNZ59_RS16275 ENOG4107S01 Repressor protein MetJ FNZ59_RS16285 ENOG4105C28 cystathionine FNZ59_RS16290 ENOG4105CFH Aspartokinase FNZ59_RS16295 ENOG4105SYT Methylenetetrahydrofolate reductase FNZ59_RS16300 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) FNZ59_RS16305 ENOG4108Q5Y Membrane FNZ59_RS16310 ENOG4108XC3 NADH ubiquinone oxidoreductase FNZ59_RS16315 ENOG4105DCT glycerol dehydrogenase FNZ59_RS16320 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FNZ59_RS16325 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FNZ59_RS16330 ENOG4105DM4 PTS System FNZ59_RS16335 ENOG4108YRF PTS System FNZ59_RS16340 ENOG4105C6N Formate acetyltransferase FNZ59_RS16345 ENOG4108AHH pyruvate formate lyase II activase FNZ59_RS16350 ENOG4108XCZ PTS System FNZ59_RS16355 ENOG4106R3P AraC family transcriptional regulator FNZ59_RS16360 ENOG4105DIJ Phosphoethanolamine transferase FNZ59_RS16375 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FNZ59_RS16380 ENOG4105CAS nag kinase FNZ59_RS16390 ENOG4105C5Q Transcriptional regulator FNZ59_RS16400 ENOG4105EJ2 Transcriptional regulator FNZ59_RS16405 ENOG4108Y73 Membrane FNZ59_RS16415 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) FNZ59_RS16450 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase FNZ59_RS16485 ENOG4105PM1 preprotein translocase subunit SecE FNZ59_RS16490 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FNZ59_RS16525 ENOG410645W Thiamin biosynthesis protein ThiH FNZ59_RS16530 ENOG4105D41 biosynthesis protein thiH FNZ59_RS16540 ENOG4105WHD thiamine biosynthesis protein ThiS FNZ59_RS16545 ENOG4105D06 uba thif-type nad fad binding protein FNZ59_RS16555 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) FNZ59_RS16580 ENOG4105R2J Conserved Protein FNZ59_RS16585 ENOG4105K70 DNA-binding protein FNZ59_RS16590 ENOG4108T8B Protein of unknown function (DUF1481) FNZ59_RS16595 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism FNZ59_RS16600 ENOG4105BZU Histidine kinase FNZ59_RS16605 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FNZ59_RS16610 ENOG4105C12 Phosphoribosylglycinamide synthetase FNZ59_RS16640 ENOG4105K5X acetyltransferase FNZ59_RS16645 ENOG4105CVG Homoserine O-transsuccinylase FNZ59_RS16650 ENOG4107QP3 malate synthase g FNZ59_RS16655 ENOG4108I9X Isocitrate lyase FNZ59_RS16660 ENOG4105VS7 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) FNZ59_RS16670 ENOG41069M3 Transcriptional regulator FNZ59_RS16675 ENOG4105C3R Methionine synthase FNZ59_RS16680 ENOG4105EAM Na Pi-cotransporter FNZ59_RS16690 ENOG4105FE9 pseudouridine synthase FNZ59_RS16695 ENOG4108ZR5 Conserved Protein FNZ59_RS16700 ENOG4105CFH Aspartokinase FNZ59_RS16715 ENOG4108MDC (LipO)protein FNZ59_RS16720 ENOG4108Q9C Periplasmic Protein FNZ59_RS16725 ENOG4105E3R (LipO)protein FNZ59_RS16745 ENOG4107QNK )-transporter FNZ59_RS16750 ENOG4105EG2 ABC transporter, permease FNZ59_RS16755 ENOG4105D56 permease protein FNZ59_RS16760 ENOG4107FKK extracellular solute-binding protein family 1 FNZ59_RS16765 ENOG4108IJ9 (ABC) transporter FNZ59_RS16775 ENOG4107W52 maltose operon periplasmic protein FNZ59_RS16800 ENOG41080IJ Diacylglycerol kinase FNZ59_RS16810 ENOG4107R73 Mate efflux family protein FNZ59_RS16815 ENOG4105VDW Csbd family FNZ59_RS16820 ENOG4105MYN Zinc uptake regulation protein FNZ59_RS16835 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FNZ59_RS16840 ENOG4105P4Z Phage shock protein G FNZ59_RS16845 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FNZ59_RS16850 ENOG4105CDU Replicative dna helicase FNZ59_RS16855 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FNZ59_RS16860 ENOG4105CGF Aromatic amino acid aminotransferase FNZ59_RS16870 ENOG4105F0S class B acid phosphatase FNZ59_RS16875 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FNZ59_RS16880 ENOG4105MSB protein, conserved in bacteria FNZ59_RS16885 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FNZ59_RS16890 ENOG4108UUM single-stranded DNA-binding protein FNZ59_RS16895 ENOG4105PMV Membrane FNZ59_RS16900 ENOG4108M8H domain protein FNZ59_RS16905 ENOG4108W3Q Transcriptional regulator FNZ59_RS16910 ENOG4108Z4X TRANSCRIPTIONal FNZ59_RS16915 ENOG4105C7N Xanthine uracil vitamin C permease FNZ59_RS16920 ENOG4105EEQ Na H antiporter FNZ59_RS16935 ENOG41062QD Membrane FNZ59_RS16940 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FNZ59_RS16950 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit FNZ59_RS16955 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FNZ59_RS16960 ENOG4105DVI reductase, NrfD FNZ59_RS16965 ENOG4108QKW cytochrome c-type biogenesis protein FNZ59_RS16975 ENOG4108W0S formate-dependent nitrite reductase complex FNZ59_RS16980 ENOG4105CK2 sodium dicarboxylate symporter FNZ59_RS16985 ENOG41082ND Uncharacterized protein yjcO FNZ59_RS16995 ENOG4105ETP RND efflux system, outer membrane lipoprotein FNZ59_RS17000 ENOG4108MI0 Resistance protein FNZ59_RS17005 ENOG4105J12 Multidrug resistance protein mdtN FNZ59_RS17010 ENOG4106833 FNZ59_RS17015 ENOG4105EUZ Beta-lactamase domain protein FNZ59_RS17020 ENOG4107TFG D-allose kinase FNZ59_RS17025 ENOG4105UP7 3-epimerase FNZ59_RS17030 ENOG4105CNN ABC, transporter FNZ59_RS17035 ENOG4105C2J ABC transporter FNZ59_RS17040 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FNZ59_RS17045 ENOG4105NYY transcriptional regulator, RpiR FNZ59_RS17050 ENOG4108YZG isomerase FNZ59_RS17055 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 FNZ59_RS17060 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein FNZ59_RS17065 ENOG410849A acetyltransferase, (GNAT) family FNZ59_RS17070 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) FNZ59_RS17075 ENOG4105FD8 phosphonate metabolism protein PhnM FNZ59_RS17080 ENOG4105HRV phosphonate c-p lyase system protein phnl FNZ59_RS17085 ENOG4105ENV phosphonate C-P lyase system protein PhnK FNZ59_RS17090 ENOG4105FT8 Phosphonate metabolism FNZ59_RS17095 ENOG4105EKV Phosphonate metabolism protein FNZ59_RS17100 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH FNZ59_RS17105 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG FNZ59_RS17110 ENOG4107RJJ Transcriptional regulator FNZ59_RS17120 ENOG4105EHI Phosphonate ABC transporter, periplasmic FNZ59_RS17125 ENOG4105D5T phosphonate abc transporter FNZ59_RS17130 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase FNZ59_RS17135 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FNZ59_RS17140 ENOG4108F5E vimentin FNZ59_RS17145 ENOG4108YIV FNZ59_RS17150 ENOG4105CSH Transporter FNZ59_RS17160 ENOG4105ECM Sensor protein basS pmrB FNZ59_RS17165 ENOG4105XJC Two component transcriptional regulator (Winged helix family FNZ59_RS17170 ENOG4105DIJ Phosphoethanolamine transferase FNZ59_RS17175 ENOG4105D5Q Arginine ornithine antiporter FNZ59_RS17180 ENOG4106ZGR Transcriptional regulator FNZ59_RS17185 ENOG4105CXN decarboxylase FNZ59_RS17190 ENOG4108K2B transcriptional regulator FNZ59_RS17195 ENOG4105F8D glycoside hydrolase family 4 FNZ59_RS17200 ENOG4105CT4 transporter FNZ59_RS17205 ENOG4108R5S membrane FNZ59_RS17210 ENOG4107GFK fumarate FNZ59_RS17215 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FNZ59_RS17220 ENOG4108MRH transcriptional regulatory protein FNZ59_RS17225 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FNZ59_RS17230 ENOG4105VR1 Pfam:DUF1271 FNZ59_RS17235 ENOG410830R acetyltransferase FNZ59_RS17250 ENOG4105CRK lysyL-tRNA synthetase FNZ59_RS17255 ENOG4105DUX Transporter FNZ59_RS17260 ENOG4105CXN decarboxylase FNZ59_RS17265 ENOG4105D5Q Arginine ornithine antiporter FNZ59_RS17270 ENOG4108M3R transcriptional activator CadC FNZ59_RS17295 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FNZ59_RS17300 ENOG4106WJE Protein of unknown function (DUF987) FNZ59_RS17305 ENOG4108YGG dna repair protein FNZ59_RS17310 ENOG4106549 Antirestriction protein FNZ59_RS17315 ENOG4106H6R UPF0380 protein FNZ59_RS17330 ENOG4108KZE transcriptional regulator FNZ59_RS17335 ENOG4105TS0 gtp-binding protein FNZ59_RS17425 ENOG4105T40 surface antigen msp4 family protein FNZ59_RS17430 ENOG4108I6E Sulfatase FNZ59_RS17445 ENOG4108SIC Transcriptional regulator FNZ59_RS17460 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FNZ59_RS17465 ENOG4108IJ0 Aspartate ammonia-lyase FNZ59_RS17470 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 FNZ59_RS17475 ENOG4105DVH amino acid FNZ59_RS17490 ENOG4108ZVF (LipO)protein FNZ59_RS17495 ENOG4105MTB Uncharacterized protein YjeJ FNZ59_RS17500 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FNZ59_RS17510 ENOG4106HKS Entericidin EcnA/B family FNZ59_RS17515 ENOG4106BSU Entericidin B FNZ59_RS17520 ENOG4105KPY Small multidrug resistance protein FNZ59_RS17525 ENOG4105QNF Outer membrane lipoprotein FNZ59_RS17530 ENOG41066YJ Beta-lactamase FNZ59_RS17545 ENOG4105E33 succinate dehydrogenase FNZ59_RS17550 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FNZ59_RS17560 ENOG4107SC7 Inner membrane transporter yjeM FNZ59_RS17565 ENOG4105EGS Mechanosensitive ion channel FNZ59_RS17605 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FNZ59_RS17610 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FNZ59_RS17615 ENOG4105K8N protein family UPF0079, ATPase FNZ59_RS17620 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FNZ59_RS17635 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FNZ59_RS17640 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FNZ59_RS17645 ENOG4107QJR hflk protein FNZ59_RS17650 ENOG4105EPW hflc protein FNZ59_RS17670 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FNZ59_RS17675 ENOG4105C2N RNA methyltransferase TrmH family group 3 FNZ59_RS17680 ENOG4105FUX Conserved Protein FNZ59_RS17685 ENOG4108P9J Phage shock protein A FNZ59_RS17690 ENOG4107VNS Protein of unknown function (DUF2491) FNZ59_RS17695 ENOG4105Z6B inner membrane protein yjfl FNZ59_RS17700 ENOG4108KXT Conserved Protein FNZ59_RS17710 ENOG4105CSU acyl-Coa dehydrogenase FNZ59_RS17715 ENOG4105S17 UPF0379 protein yjfN FNZ59_RS17720 ENOG4105WSB biofilm stress and motility protein A FNZ59_RS17725 ENOG4108MXZ Esterase FNZ59_RS17740 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FNZ59_RS17745 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport FNZ59_RS17750 ENOG4106ETB IIa component FNZ59_RS17770 ENOG4105KIT UPF0379 protein yjfY FNZ59_RS17785 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FNZ59_RS17795 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FNZ59_RS17800 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FNZ59_RS17805 ENOG41069H7 transport system small permease component FNZ59_RS17810 ENOG4107S3R L-aspartate oxidase FNZ59_RS17815 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FNZ59_RS17820 ENOG4105E39 Enoyl-CoA hydratase FNZ59_RS17830 ENOG4105CHR reductase FNZ59_RS17840 ENOG4105FHY Opacity-associated protein A FNZ59_RS17845 ENOG4108V1T peptidylprolyl cis-trans isomerase FNZ59_RS17850 ENOG4105C85 amino acid FNZ59_RS17860 ENOG4105DXC membrane FNZ59_RS17865 ENOG4105ECR NmrA family FNZ59_RS17870 ENOG4105KVH Transcriptional regulator FNZ59_RS17875 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic FNZ59_RS17880 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FNZ59_RS17885 ENOG4108UUE Transcriptional regulator FNZ59_RS17890 ENOG41061GZ Protein of unknown function (DUF1107) FNZ59_RS17895 ENOG4105C37 (CBS) domain FNZ59_RS17905 ENOG4105CFU surface antigen FNZ59_RS17910 ENOG4105MA0 exported protein FNZ59_RS17915 ENOG4108ZHD aig2 family FNZ59_RS17920 ENOG4105F0N pyrophosphate phospho-hydrolase FNZ59_RS17925 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator FNZ59_RS17930 ENOG4105C2J ABC transporter FNZ59_RS17935 ENOG4107R9N ABC transporter FNZ59_RS17950 ENOG4105DFU Cell wall formation (By similarity) FNZ59_RS17960 ENOG4105CMS peptidase U62, modulator of DNA gyrase FNZ59_RS17970 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) FNZ59_RS17975 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FNZ59_RS17980 ENOG4105CG3 alpha amylase, catalytic region FNZ59_RS17985 ENOG4105C5Y PTS System FNZ59_RS17990 ENOG4105D4X repressor FNZ59_RS18000 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FNZ59_RS18005 ENOG4105KME endoribonuclease L-psp FNZ59_RS18020 ENOG41077AM PyrBI operon attenuator FNZ59_RS18025 ENOG4108UQ8 endoribonuclease L-psp FNZ59_RS18030 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FNZ59_RS18035 ENOG4108XFH Transcriptional regulator FNZ59_RS18040 ENOG4105XEP YhcH YjgK YiaL family protein FNZ59_RS18065 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) FNZ59_RS18070 ENOG4108MJ3 acetyltransferase FNZ59_RS18075 ENOG4108M3P Membrane FNZ59_RS18080 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FNZ59_RS18085 ENOG4105MYG DNA polymerase iii, chi subunit FNZ59_RS18095 ENOG4108M8S permease YjgP YjgQ family protein FNZ59_RS18100 ENOG4108K5H permease YjgP YjgQ family protein FNZ59_RS18105 ENOG4105D7A ATP-binding protein FNZ59_RS18110 ENOG4105DQ4 alcohol dehydrogenase FNZ59_RS18150 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 FNZ59_RS18175 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) FNZ59_RS18180 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria FNZ59_RS18185 ENOG4108W9T type 1 fimbriae regulatory protein FNZ59_RS18190 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off FNZ59_RS18200 ENOG4108S54 Fimbrial protein FNZ59_RS18205 ENOG4108NAE Fimbrial chaperone protein FNZ59_RS18210 ENOG4105CW0 outer membrane usher protein FNZ59_RS18215 ENOG4108SQA Fimbrial FNZ59_RS18220 ENOG4108T65 Fimbrial FNZ59_RS18225 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin FNZ59_RS18240 ENOG4105DEI Mannitol dehydrogenase FNZ59_RS18245 ENOG4105C6F GntR Family Transcriptional Regulator FNZ59_RS18265 ENOG4107YNJ LysR family Transcriptional regulator FNZ59_RS18270 ENOG4105DYB Isoaspartyl dipeptidase FNZ59_RS18275 ENOG4108P2H Inner membrane protein YjiG FNZ59_RS18280 ENOG41074DU domain protein FNZ59_RS18290 ENOG4105CBP Major Facilitator FNZ59_RS18305 ENOG4105CIZ coA-substrate-specific enzyme activase FNZ59_RS18310 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase FNZ59_RS18315 ENOG4106BRA Membrane FNZ59_RS18320 ENOG41083G8 Multidrug resistance protein MdtM FNZ59_RS18335 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FNZ59_RS18340 ENOG4106DIZ Domain of unknown function (DUF1127) FNZ59_RS18370 ENOG4107SQC 5-methylcytosine-specific restriction enzyme subunit McrC FNZ59_RS18375 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 FNZ59_RS18385 ENOG4107XZC Restriction modification system DNA (Specificity FNZ59_RS18390 ENOG4105CVR type I restriction-modification system FNZ59_RS18395 ENOG4107SCJ type I restriction enzyme EcoKI subunit R FNZ59_RS18400 ENOG4106H3A restriction FNZ59_RS18405 ENOG4105CKI cobalamin synthesis protein FNZ59_RS18410 ENOG4105VCD cytoplasmic protein FNZ59_RS18415 ENOG4105D22 carbon starvation protein FNZ59_RS18420 ENOG4107UWN reductase FNZ59_RS18425 ENOG4105EFA 4-hydroxyphenylacetate FNZ59_RS18455 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase FNZ59_RS18460 ENOG4105C26 Dehydrogenase FNZ59_RS18465 ENOG4105ERH Fumarylacetoacetate hydrolase FNZ59_RS18470 ENOG4108V8F Transcriptional regulator, MarR family FNZ59_RS18475 ENOG4105C8Q Methyl-accepting chemotaxis FNZ59_RS18480 ENOG4108I5G Major Facilitator superfamily FNZ59_RS18485 ENOG410617M Transcriptional regulator FNZ59_RS18490 ENOG4105CPQ Dehydrogenase FNZ59_RS18500 ENOG4105RI1 glycoprotein receptor FNZ59_RS18505 ENOG4106CVF DNA replication protein FNZ59_RS18515 ENOG4107XM3 UPF0442 protein FNZ59_RS18520 ENOG4105DWK Membrane FNZ59_RS18525 ENOG4108N8T regulatoR FNZ59_RS18530 ENOG4108T94 DNA-binding transcriptional activator BglJ FNZ59_RS18535 ENOG4108819 ferric iron reductase FNZ59_RS18540 ENOG4105YBH Protein of unknown function (DUF1435) FNZ59_RS18560 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) FNZ59_RS18565 ENOG4108WPU DNA polymerase III subunit psi FNZ59_RS18570 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FNZ59_RS18575 ENOG4105PAD Hydrolase FNZ59_RS18585 ENOG4105K3G Periplasmic Protein FNZ59_RS18595 ENOG4108NRW Phospholipase, patatin family FNZ59_RS18600 ENOG4105EYA deoxyribonuclease FNZ59_RS18605 ENOG41076CZ activating enzyme FNZ59_RS18610 ENOG4105G0K glycine radical enzyme YjjI family FNZ59_RS18645 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) FNZ59_RS18650 ENOG4105EAC phosphoserine phosphatase FNZ59_RS18655 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FNZ59_RS18660 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase FNZ59_RS18665 ENOG4105C5H ABC transporter FNZ59_RS18670 ENOG4107SC1 transglycosylase FNZ59_RS18690 ENOG4105UEI Transcriptional Regulator AraC Family FNZ59_RS18695 ENOG4108RH0 Crea protein FNZ59_RS18700 ENOG4105E3W Two component transcriptional regulator (Winged helix family FNZ59_RS18705 ENOG4105EB3 Histidine kinase FNZ59_RS18710 ENOG4105CT7 inner membrane cred family protein FNZ59_RS18715 ENOG41065U4 response regulator FNZ59_RS18720 ENOG410759A FNZ59_RS18725 ENOG4106FVC RNA methyltransferase FNZ59_RS18735 ENOG4105CFH Aspartokinase FNZ59_RS18745 ENOG4105D98 threonine synthase FNZ59_RS18750 ENOG41062C6 Protein of unknown function (DUF2502) FNZ59_RS18755 ENOG4105D1Q UPF0246 protein FNZ59_RS18760 ENOG4105BZG amino acid carrier protein FNZ59_RS18770 ENOG4108RIR Molybdenum cofactor biosynthesis protein FNZ59_RS18775 ENOG4106HK8 GPR1 FUN34 yaaH family protein FNZ59_RS18780 ENOG4108QUJ UPF0174 protein YaaW FNZ59_RS18800 ENOG4108SER Transposase FNZ59_RS18805 ENOG4105WI6 cell killing protein encoded within cryptic prophage FNZ59_RS18810 ENOG4105F9F transposase FNZ59_RS18820 ENOG41063Z6 transcriptional regulator, lysR family FNZ59_RS18845 ENOG410647N response to DNA damage stimulus FNZ59_RS18850 ENOG4105DTN riboflavin biosynthesis protein ribF FNZ59_RS18865 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FNZ59_RS18885 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FNZ59_RS18890 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FNZ59_RS18895 ENOG4108XNW Transcriptional activatory protein CaiF FNZ59_RS18905 ENOG4106YT9 Enoyl-CoA hydratase FNZ59_RS18910 ENOG4105CEY Amp-dependent synthetase and ligase FNZ59_RS18940 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FNZ59_RS18945 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein FNZ59_RS18965 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FNZ59_RS18990 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FNZ59_RS18995 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FNZ59_RS19000 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) FNZ59_RS19005 ENOG4105D3G Pseudouridine synthase FNZ59_RS19015 ENOG4105CQ2 DNA polymerase FNZ59_RS19020 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FNZ59_RS19030 ENOG4105EF1 ribulokinase FNZ59_RS19035 ENOG41063TF transcriptional regulator (AraC FNZ59_RS19040 ENOG4108KF1 Membrane FNZ59_RS19050 ENOG4106SMU thiamine transporter membrane protein FNZ59_RS19055 ENOG4105DP9 ABC transporter FNZ59_RS19070 ENOG4105S8Q sugar efflux transporter FNZ59_RS19085 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FNZ59_RS19100 ENOG41064T2 transcriptional regulator, lysR family FNZ59_RS19110 ENOG4105C7K acetolactate synthase FNZ59_RS19115 ENOG4108ZP8 Acetolactate synthase small subunit FNZ59_RS19125 ENOG4107B7Y DNA-binding transcriptional regulator FruR FNZ59_RS19130 ENOG4108V6E Cell division protein mraZ FNZ59_RS19140 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FNZ59_RS19145 ENOG4105CJN penicillin-binding protein FNZ59_RS19150 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FNZ59_RS19155 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FNZ59_RS19165 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FNZ59_RS19170 ENOG4105CNI cell division protein FtsW FNZ59_RS19185 ENOG4105CPF Cell wall formation (By similarity) FNZ59_RS19190 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FNZ59_RS19195 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FNZ59_RS19200 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FNZ59_RS19220 ENOG4105M6F mutator MutT protein FNZ59_RS19235 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FNZ59_RS19245 ENOG4105D7Q type ii secretion system FNZ59_RS19250 ENOG4107QHF type ii secretion system protein e FNZ59_RS19255 ENOG4108ZUW Major pilin subunit FNZ59_RS19260 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FNZ59_RS19265 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FNZ59_RS19270 ENOG4106A72 regulatory protein AmpE FNZ59_RS19275 ENOG4105C85 amino acid FNZ59_RS19280 ENOG41073TP transcriptional regulator FNZ59_RS19285 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FNZ59_RS19290 ENOG4107QSN dihydrolipoamide acetyltransferase FNZ59_RS19295 ENOG4107QN2 dihydrolipoyl dehydrogenase FNZ59_RS19300 ENOG4108NST exported protein FNZ59_RS19305 ENOG4107QIJ Aconitate hydratase 2 FNZ59_RS19325 ENOG4108ZRK uncharacterized protein yacC FNZ59_RS19330 ENOG4105E3B Multicopper oxidase FNZ59_RS19335 ENOG4105DZG Dehydrogenase FNZ59_RS19340 ENOG4108UGV hypoxanthine phosphoribosyltransferase FNZ59_RS19345 ENOG41077A9 carbonic anhydrase FNZ59_RS19350 ENOG4105DA5 (ABC) transporter FNZ59_RS19355 ENOG4105E3A (ABC) transporter FNZ59_RS19360 ENOG4108YTN IIa component FNZ59_RS19365 ENOG4107BJW polysaccharide deacetylase FNZ59_RS19375 ENOG4108A32 Transposase FNZ59_RS19390 ENOG4105P0Q fimbrial-like protein YadC FNZ59_RS19395 ENOG4105SN2 fimbrial-like adhesin protein FNZ59_RS19400 ENOG4105SYG Fimbrial protein FNZ59_RS19405 ENOG4108XEY fimbrial-like adhesin protein FNZ59_RS19410 ENOG4105CW0 outer membrane usher protein FNZ59_RS19415 ENOG4108VEV chaperone FNZ59_RS19425 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FNZ59_RS19430 ENOG4105DJ0 Poly(A) Polymerase FNZ59_RS19440 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters FNZ59_RS19450 ENOG4107XID 2'-5' rna ligase FNZ59_RS19455 ENOG4105CQ7 ATP-dependent helicase FNZ59_RS19460 ENOG4105BZ4 penicillin-binding protein FNZ59_RS19465 ENOG4105E0K tonB-dependent siderophore receptor FNZ59_RS19470 ENOG4105E0A ABC, transporter FNZ59_RS19475 ENOG4105J76 Periplasmic binding protein FNZ59_RS19480 ENOG4105S6R Iron-hydroxamate transporter permease subunit FNZ59_RS19505 ENOG4105EN6 Membrane FNZ59_RS19510 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FNZ59_RS19525 ENOG4105C0H protease FNZ59_RS19530 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR FNZ59_RS19540 ENOG4105DIN metallophosphoesterase FNZ59_RS19555 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FNZ59_RS19580 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FNZ59_RS19585 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FNZ59_RS19590 ENOG4105KNE Phosphatidate cytidylyltransferase FNZ59_RS19595 ENOG4105DZP Membrane-associated zinc metalloprotease FNZ59_RS19605 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) FNZ59_RS19610 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FNZ59_RS19635 ENOG4105C0B DNA polymerase III (alpha subunit) FNZ59_RS19645 ENOG4105CXN decarboxylase FNZ59_RS19650 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FNZ59_RS19655 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FNZ59_RS19660 ENOG4105M1T rho-binding antiterminator FNZ59_RS19670 ENOG4108VWS Yaeq family FNZ59_RS19675 ENOG4108YZN class I peptide chain release factor FNZ59_RS19680 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion FNZ59_RS19685 ENOG4108UY0 (LipO)protein FNZ59_RS19695 ENOG4108R96 Methyltransferase, YaeB family FNZ59_RS19700 ENOG4108R8X outer membrane lipoprotein FNZ59_RS19705 ENOG4105D01 (LipO)protein FNZ59_RS19710 ENOG4108UMI ABC transporter, permease FNZ59_RS19715 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FNZ59_RS19720 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FNZ59_RS19755 ENOG4105CV8 reductase FNZ59_RS19760 ENOG4105HEI LysR family (Transcriptional regulator FNZ59_RS19770 ENOG4105F2W methyltransferase FNZ59_RS19775 ENOG4105E9H Lytic Murein transglycosylase FNZ59_RS19780 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FNZ59_RS19785 ENOG4105D1A Methyltransferase FNZ59_RS19795 ENOG4107RZZ dna polymerase iii epsilon subunit FNZ59_RS19805 ENOG410600K aminopeptidase FNZ59_RS19820 ENOG4105GMB type VI secretion system effector, hcp1 family FNZ59_RS19880 ENOG410600T transposase FNZ59_RS19885 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FNZ59_RS19890 ENOG4108WN0 inhibitor of vertebrate lysozyme FNZ59_RS19895 ENOG4107QPN acyl-Coa dehydrogenase FNZ59_RS19905 ENOG4105E7A Glutamine amidotransferase FNZ59_RS19910 ENOG4105F7V ErfK ybiS ycfS ynhG family protein FNZ59_RS19915 ENOG4105VXN addiction module toxin, RelE StbE family FNZ59_RS19925 ENOG4108YS0 lipoprotein YafL FNZ59_RS19930 ENOG4108UK5 Transposase FNZ59_RS19945 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FNZ59_RS19950 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system FNZ59_RS19955 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome FNZ59_RS19960 ENOG4108HYG acetyltransferase FNZ59_RS19970 ENOG4108S2Y peptide Chain Release factor FNZ59_RS19975 ENOG4105CIN aminoacyl-histidine dipeptidase FNZ59_RS19995 ENOG4105FCK Membrane FNZ59_RS20035 ENOG4108P8R FNZ59_RS20065 ENOG4107FKK extracellular solute-binding protein family 1 FNZ59_RS20075 ENOG4105EG2 ABC transporter, permease FNZ59_RS20085 ENOG4105C4C beta-galactosidase FNZ59_RS20090 ENOG4105CI1 PTS System FNZ59_RS20095 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) FNZ59_RS20100 ENOG4105ETE Transcriptional regulator (LacI family FNZ59_RS20120 ENOG4105F4K antigen 43 FNZ59_RS20140 ENOG4108YGG dna repair protein FNZ59_RS20145 ENOG4106WJE Protein of unknown function (DUF987) FNZ59_RS20150 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FNZ59_RS20185 ENOG4107XAN XdhC and CoxI family FNZ59_RS20190 ENOG4105C7W Xanthine dehydrogenase FNZ59_RS20195 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding FNZ59_RS20200 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit FNZ59_RS20205 ENOG4105R3P Inner membrane protein yagU FNZ59_RS20215 ENOG4105R3P Inner membrane protein yagU FNZ59_RS20220 ENOG4105PI0 Ferredoxin FNZ59_RS20225 ENOG4108UD7 cell wall organization FNZ59_RS20230 ENOG4106PYX Receptor FNZ59_RS20265 ENOG4105NRA 50s ribosomal protein l31 type b FNZ59_RS20295 ENOG4108KBJ Inner membrane protein YkgB FNZ59_RS20300 ENOG41066GK UPF0379 protein ykgI FNZ59_RS20305 ENOG4107QN2 dihydrolipoyl dehydrogenase FNZ59_RS20310 ENOG4108K01 transcriptional regulator FNZ59_RS20315 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FNZ59_RS20320 ENOG4107QR9 Iron-sulfur cluster binding protein FNZ59_RS20325 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) FNZ59_RS20335 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) FNZ59_RS20345 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) FNZ59_RS20350 ENOG4105C94 Transporter FNZ59_RS20360 ENOG4105BZU Histidine kinase FNZ59_RS20365 ENOG4108NUU Transcriptional regulator FNZ59_RS20370 ENOG4105SZ2 membrAne FNZ59_RS20375 ENOG4107SNB ankyrin repeat protein YahD FNZ59_RS20380 ENOG4105N16 Protein of unknown function (DUF2877) FNZ59_RS20385 ENOG4107R1Q Membrane protein FdrA FNZ59_RS20390 ENOG4107REC cytoplasmic protein FNZ59_RS20400 ENOG4105DND Transcriptional regulator FNZ59_RS20405 ENOG4107B2H carbonic anhydrase FNZ59_RS20410 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) FNZ59_RS20415 ENOG4105DJ2 Major Facilitator Superfamily FNZ59_RS20420 ENOG4108UW5 maltose o-acetyltransferase FNZ59_RS20425 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FNZ59_RS20430 ENOG4105CNT hydrolase family 2 FNZ59_RS20435 ENOG4105ETE Transcriptional regulator (LacI family FNZ59_RS20440 ENOG4108K2P TRANSCRIPTIONal FNZ59_RS20450 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) FNZ59_RS20475 ENOG4108SC4 )-transporter FNZ59_RS20480 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FNZ59_RS20485 ENOG4105C4W S-formylglutathione hydrolase FNZ59_RS20500 ENOG4105SRB Uncharacterized protein yaiO FNZ59_RS20510 ENOG4108PBI Polysaccharide metabolism FNZ59_RS20515 ENOG4107W19 lmbE family FNZ59_RS20520 ENOG4106FTQ Taurine ABC transporter, periplasmic FNZ59_RS20525 ENOG4108ETV ABC transporter FNZ59_RS20530 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FNZ59_RS20535 ENOG4105E2B Taurine dioxygenase FNZ59_RS20540 ENOG4105D52 delta-aminolevulinic acid dehydratase FNZ59_RS20550 ENOG4108PNB DNA-binding transcriptional regulator FNZ59_RS20555 ENOG4107R6D beta-lactam binding protein AmpH FNZ59_RS20560 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 FNZ59_RS20565 ENOG4107QS8 (LipO)protein FNZ59_RS20570 ENOG4105FR5 inner membrane protein YaiY FNZ59_RS20575 ENOG4105UNH Membrane FNZ59_RS20580 ENOG4105CPF Cell wall formation (By similarity) FNZ59_RS20590 ENOG4105G6Z alkaline phosphatase FNZ59_RS20595 ENOG4105VIF phosphate starvation-inducible protein FNZ59_RS20600 ENOG4105BZU Histidine kinase FNZ59_RS20605 ENOG4105II7 pyrroline-5-carboxylate reductase FNZ59_RS20610 ENOG4108UPT UPF0178 protein FNZ59_RS20620 ENOG4105SS3 FNZ59_RS20625 ENOG4105HBA AroM protein FNZ59_RS20650 ENOG4105DKQ ROK family FNZ59_RS20655 ENOG4105F27 Major Facilitator FNZ59_RS20660 ENOG4105EYH Exonuclease FNZ59_RS20665 ENOG4107RH8 nuclease SbcCD subunit D FNZ59_RS20670 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FNZ59_RS20675 ENOG4105BZU Histidine kinase FNZ59_RS20680 ENOG4105CWM branched-chain amino acid transport system II carrier protein FNZ59_RS20685 ENOG4105C85 amino acid FNZ59_RS20690 ENOG4107R28 alpha amylase, catalytic region FNZ59_RS20710 ENOG4105VIE preprotein translocase, subunit YajC FNZ59_RS20715 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FNZ59_RS20720 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FNZ59_RS20725 ENOG4105N1F Hnh endonuclease FNZ59_RS20730 ENOG4105DRB nucleoside-specific channel-forming protein FNZ59_RS20735 ENOG4108KIC (LipO)protein FNZ59_RS20745 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FNZ59_RS20750 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FNZ59_RS20760 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FNZ59_RS20765 ENOG4108ZAI phosphatidylglycerophosphatase a FNZ59_RS20770 ENOG4105CPC Aldo Keto reductase FNZ59_RS20780 ENOG4105CTB Polyprenyl synthetase FNZ59_RS20795 ENOG4107S0N DJ-1 family FNZ59_RS20800 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FNZ59_RS20810 ENOG4107RDB Major Facilitator FNZ59_RS20835 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FNZ59_RS20840 ENOG4105CCU oxidase (Subunit III) FNZ59_RS20845 ENOG4105BZ9 Cytochrome C oxidase, subunit I FNZ59_RS20850 ENOG4105E2S oxidase) subunit II FNZ59_RS20855 ENOG4105EYM Major Facilitator superfamily FNZ59_RS20860 ENOG4105IEY (LipO)protein FNZ59_RS20865 ENOG4105M85 Bola protein FNZ59_RS20885 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FNZ59_RS20890 ENOG4105K70 DNA-binding protein FNZ59_RS20895 ENOG4105EIN peptidylprolyl cis-trans isomerase FNZ59_RS20900 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FNZ59_RS20905 ENOG4108TGP Thioesterase superfamily protein FNZ59_RS20915 ENOG4108NFA extracellular solute-binding protein FNZ59_RS20925 ENOG4108XM1 transcriptional regulator AsnC family FNZ59_RS20930 ENOG4105BZ1 (ABC) transporter FNZ59_RS20935 ENOG4105BZ1 (ABC) transporter FNZ59_RS20940 ENOG4108YZA Nitrogen regulatory protein pii FNZ59_RS20945 ENOG4105BZU Histidine kinase FNZ59_RS20950 ENOG4105C29 acyl-CoA thioesterase FNZ59_RS20955 ENOG4108MNP Glycoprotein polysaccharide metabolism FNZ59_RS20960 ENOG41080UX Methyltransferase FNZ59_RS20970 ENOG4105KCV RNA signal recognition particle 4.5S RNA FNZ59_RS20975 ENOG41066DG (EAL) domain protein FNZ59_RS20980 ENOG4105GSJ Inner membrane protein ylaC FNZ59_RS20985 ENOG4108UW5 maltose o-acetyltransferase FNZ59_RS20990 ENOG4105KF5 hemolysin expression-modulating protein FNZ59_RS20995 ENOG4108UKR Biofilm formation regulator YbaJ FNZ59_RS21000 ENOG4105BZS acriflavin resistance protein FNZ59_RS21005 ENOG4105C1P efflux transporter, rnd family, mfp subunit FNZ59_RS21010 ENOG4108IG5 Transcriptional regulator FNZ59_RS21015 ENOG4105EGS Mechanosensitive ion channel FNZ59_RS21020 ENOG4106428 Protein of unknown function (DUF2496) FNZ59_RS21025 ENOG4108URS primosomal replication protein n'' FNZ59_RS21030 ENOG4105WD1 Membrane FNZ59_RS21040 ENOG4107QMP dna polymerase iii subunits gamma and tau FNZ59_RS21055 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FNZ59_RS21075 ENOG4107RE1 Inosine-guanosine kinase FNZ59_RS21080 ENOG4105CKD glutathione-regulated potassium-efflux system protein FNZ59_RS21085 ENOG4105EU0 Major facilitator Superfamily FNZ59_RS21090 ENOG4105CGH 5'-nucleotidase FNZ59_RS21095 ENOG4108Z66 YbaK ebsC protein FNZ59_RS21100 ENOG4105MBR gumn family FNZ59_RS21105 ENOG41081XE plasmid maintenance system antidote protein, xre family FNZ59_RS21110 ENOG4105C59 p-type ATPase FNZ59_RS21115 ENOG4105CSV Glutaminase FNZ59_RS21120 ENOG4107RY6 amino acid FNZ59_RS21125 ENOG4108Z6Z Transcriptional regulator FNZ59_RS21130 ENOG4105G5H Membrane FNZ59_RS21135 ENOG4107QX8 SPFH domain, Band 7 family protein FNZ59_RS21140 ENOG41083J0 (ABC) transporter FNZ59_RS21145 ENOG4105C4B ABC transporter, permease FNZ59_RS21150 ENOG4107QR8 Thioredoxin FNZ59_RS21155 ENOG4105E1F short-chain dehydrogenase reductase FNZ59_RS21160 ENOG4108UJV acyl-CoA thioesterase i FNZ59_RS21165 ENOG4108I0Y (ABC) transporter FNZ59_RS21170 ENOG4105CV6 ABC transporter, permease FNZ59_RS21175 ENOG4105CNA YD repeat protein FNZ59_RS21205 ENOG4107653 Transcriptional regulator FNZ59_RS21210 ENOG4108Z2U ureidoglycolate hydrolase FNZ59_RS21215 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region FNZ59_RS21220 ENOG41060W2 glyoxylate carboligase FNZ59_RS21225 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FNZ59_RS21230 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FNZ59_RS21235 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FNZ59_RS21245 ENOG4105DTE Xanthine uracil vitamin C permease FNZ59_RS21250 ENOG4105BZW Glycerate kinase FNZ59_RS21255 ENOG4105S0E allantoin catabolism protein FNZ59_RS21260 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FNZ59_RS21265 ENOG4105DG4 malate L-lactate dehydrogenase FNZ59_RS21270 ENOG4107R1Q Membrane protein FdrA FNZ59_RS21275 ENOG4107REC cytoplasmic protein FNZ59_RS21280 ENOG4105G5A Protein of unknown function (DUF2877) FNZ59_RS21285 ENOG4105C5B carbamate kinase FNZ59_RS21290 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FNZ59_RS21295 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FNZ59_RS21305 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FNZ59_RS21315 ENOG4105S2T inner membrane protein YbcI FNZ59_RS21320 ENOG4105WQ3 Rna-binding protein FNZ59_RS21330 ENOG4108WDE Fimbrial protein FNZ59_RS21335 ENOG4108AF8 Chaperone FNZ59_RS21340 ENOG4105CW0 outer membrane usher protein FNZ59_RS21345 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) FNZ59_RS21350 ENOG4108ZI2 Fimbrial protein FNZ59_RS21355 ENOG4108Q9V regulatoR FNZ59_RS21365 ENOG4108KU3 Integrase FNZ59_RS21370 ENOG4105DQ6 Transposase FNZ59_RS21380 ENOG41064WM Uncharacterized protein YcgX FNZ59_RS21385 ENOG4106YSC FNZ59_RS21400 ENOG4105UZW Tail fiber assembly protein FNZ59_RS21405 ENOG4108WF3 methyltransferase FNZ59_RS21420 ENOG4108NC2 Outer membrane protease FNZ59_RS21440 ENOG4105CS6 Rhs element vgr protein FNZ59_RS21445 ENOG4105GR3 Histidine kinase FNZ59_RS21450 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FNZ59_RS21455 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FNZ59_RS21460 ENOG410624V efflux system protein FNZ59_RS21465 ENOG4105EP1 Efflux transporter rnd family, mfp subunit FNZ59_RS21470 ENOG4108IJF Heavy metal efflux pump, CzcA FNZ59_RS21475 ENOG4105C85 amino acid FNZ59_RS21480 ENOG4105CUY Mechanosensitive ion channel FNZ59_RS21485 ENOG4108RCM Nitroreductase FNZ59_RS21490 ENOG4105MSB protein, conserved in bacteria FNZ59_RS21495 ENOG4105WQ6 Membrane FNZ59_RS21510 ENOG4107635 Hok Gef family protein FNZ59_RS21515 ENOG4108SER Transposase FNZ59_RS21520 ENOG4108TSE Transferase FNZ59_RS21525 ENOG4107RNH Outer membrane receptor FepA FNZ59_RS21530 ENOG4105E93 esterase FNZ59_RS21535 ENOG41085A6 mbth domain-containing protein FNZ59_RS21540 ENOG4105C0W non-ribosomal peptide synthetase FNZ59_RS21545 ENOG4108QY5 Ferric enterobactin transport protein FNZ59_RS21550 ENOG4105E0A ABC, transporter FNZ59_RS21555 ENOG4105TVJ transport system, permease FNZ59_RS21560 ENOG4105DQ5 transport system permease protein FNZ59_RS21570 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein FNZ59_RS21575 ENOG4105E4F Isochorismate synthase FNZ59_RS21580 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FNZ59_RS21585 ENOG4105WQI isochorismatase FNZ59_RS21590 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FNZ59_RS21595 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) FNZ59_RS21600 ENOG4105D22 carbon starvation protein FNZ59_RS21605 ENOG4105VCD cytoplasmic protein FNZ59_RS21610 ENOG4107SCQ Iron-containing alcohol dehydrogenase FNZ59_RS21615 ENOG4105CHM Aminotransferase FNZ59_RS21620 ENOG4105GTN ParB Domain Protein Nuclease FNZ59_RS21625 ENOG4105BZV Phosphoadenosine phosphosulfate reductase FNZ59_RS21630 ENOG4105DQS Transcriptional regulator FNZ59_RS21635 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase FNZ59_RS21640 ENOG4105D3R alkyl hydroperoxide reductase FNZ59_RS21645 ENOG4108JU3 Alkyl hydroperoxide reductase FNZ59_RS21650 ENOG4108U51 Universal stress protein FNZ59_RS21655 ENOG4105E2A Dehydrogenase FNZ59_RS21660 ENOG4105NXH GreA GreB family elongation factor FNZ59_RS21665 ENOG4105KTS ribonuclease FNZ59_RS21670 ENOG4107QPK )-transporter FNZ59_RS21685 ENOG4105CHY citrate lyase, alpha FNZ59_RS21690 ENOG4105CI0 Citrate lyase FNZ59_RS21700 ENOG4105DUA (citrate (pro-3S)-lyase ligase FNZ59_RS21705 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FNZ59_RS21710 ENOG4106YYS transcriptional regulatory protein FNZ59_RS21715 ENOG4105CEE C4-dicarboxylate transporter FNZ59_RS21720 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) FNZ59_RS21725 ENOG4105VEQ Cold shock protein FNZ59_RS21735 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FNZ59_RS21740 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) FNZ59_RS21750 ENOG41064T2 transcriptional regulator, lysR family FNZ59_RS21765 ENOG4105DZ1 carboxypeptidase FNZ59_RS21770 ENOG4105K6T rare lipoprotein A FNZ59_RS21775 ENOG4105CNI cell division protein FtsW FNZ59_RS21780 ENOG4105CJN penicillin-binding protein FNZ59_RS21790 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) FNZ59_RS21795 ENOG4108TGR phosphatase FNZ59_RS21805 ENOG4105DJF DNA polymerase III, delta' subunit FNZ59_RS21820 ENOG4107PAI alpha helical protein FNZ59_RS21825 ENOG4105EUU Sel1 domain protein repeat-containing protein FNZ59_RS21830 ENOG41069CF Protein of unknown function (DUF1266) FNZ59_RS21835 ENOG4105QFC Hsc56 co-chaperone of HscC FNZ59_RS21840 ENOG4107JFD Sel1 repeat FNZ59_RS21845 ENOG41069CF Protein of unknown function (DUF1266) FNZ59_RS21850 ENOG4105QFC Hsc56 co-chaperone of HscC FNZ59_RS21855 ENOG4105F7F Chaperone FNZ59_RS21865 ENOG4105CDA abc transporter atp-binding protein FNZ59_RS21870 ENOG4105DRP amino acid AbC transporter FNZ59_RS21875 ENOG4105EAD ABC transporter FNZ59_RS21880 ENOG4107RP9 extracellular solute-binding protein, family 3 FNZ59_RS21885 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FNZ59_RS21890 ENOG4108JU5 Magnesium and cobalt efflux protein FNZ59_RS21900 ENOG4105C9A Phoh family FNZ59_RS21910 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FNZ59_RS21950 ENOG4105CAQ asparagine synthetase FNZ59_RS21955 ENOG4105D4U had-superfamily hydrolase, subfamily iia FNZ59_RS21960 ENOG4105E2R ROK family FNZ59_RS21965 ENOG4105CE4 GlcNAc 6-P deacetylase FNZ59_RS21975 ENOG4105CI1 PTS System FNZ59_RS21990 ENOG4105GX6 (LipO)protein FNZ59_RS21995 ENOG41090R7 Ferric uptake FNZ59_RS22005 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) FNZ59_RS22010 ENOG4105NNH LexA regulated protein FNZ59_RS22015 ENOG4105EV9 Alpha Beta Hydrolase FNZ59_RS22020 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) FNZ59_RS22025 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 FNZ59_RS22045 ENOG4105D5Q Arginine ornithine antiporter FNZ59_RS22050 ENOG4105CXN decarboxylase FNZ59_RS22060 ENOG4105EEX Two component transcriptional regulator (Winged helix family FNZ59_RS22065 ENOG4105C08 Histidine kinase FNZ59_RS22090 ENOG4105XIQ Protein of unknown function (DUF2517) FNZ59_RS22110 ENOG41079JQ Membrane FNZ59_RS22120 ENOG4106R09 FNZ59_RS22145 ENOG4107SEY Conserved Protein FNZ59_RS22150 ENOG4105CVP deoxyribo-dipyrimidine photolyase FNZ59_RS22155 ENOG4105DUX Transporter FNZ59_RS22160 ENOG4107QNR UPF0135 protein FNZ59_RS22165 ENOG4105P4J Allophanate hydrolase, subunit 1 FNZ59_RS22170 ENOG4107R7A Allophanate hydrolase subunit 2 FNZ59_RS22185 ENOG4108KK1 membrane protein AbrB duplication FNZ59_RS22190 ENOG4108MY7 Fimbrial FNZ59_RS22195 ENOG4108TTM chaperone FNZ59_RS22200 ENOG4106PG1 outer membrane usher protein FNZ59_RS22205 ENOG4106UBK fimbrial-like adhesin protein FNZ59_RS22210 ENOG4105BZN citrate synthase FNZ59_RS22220 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FNZ59_RS22225 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FNZ59_RS22230 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FNZ59_RS22235 ENOG4105E33 succinate dehydrogenase FNZ59_RS22240 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FNZ59_RS22245 ENOG4105C7S Dehydrogenase FNZ59_RS22255 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FNZ59_RS22260 ENOG4105FDP GntR family transcriptional regulator FNZ59_RS22265 ENOG4105DM4 PTS System FNZ59_RS22270 ENOG4105C8I hydrolase, family 38 FNZ59_RS22275 ENOG4105C4M (Ubiquinol oxidase) subunit I FNZ59_RS22280 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FNZ59_RS22290 ENOG4105KJB cyd operon protein YbgE FNZ59_RS22295 ENOG4107YD3 Thioesterase FNZ59_RS22300 ENOG4105E02 MotA TolQ exbB proton channel FNZ59_RS22305 ENOG4105M8F Biopolymer transport protein exbD tolR FNZ59_RS22310 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA FNZ59_RS22320 ENOG4105KCK Peptidoglycan-associated lipoprotein FNZ59_RS22325 ENOG4105UFD tol-pal system protein YbgF FNZ59_RS22370 ENOG4106Z1T Nicotinamide Mononucleotide Transporter FNZ59_RS22375 ENOG4105PGM cation diffusion facilitator family transporter FNZ59_RS22380 ENOG4105JND homeobox protein FNZ59_RS22385 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FNZ59_RS22395 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FNZ59_RS22405 ENOG4105F0Z galactose-1-phosphate uridylyltransferase FNZ59_RS22410 ENOG4105CMR udp-glucose 4-epimerase FNZ59_RS22415 ENOG4105DKW ABC transporter FNZ59_RS22420 ENOG4105F4R Transcriptional regulator mode FNZ59_RS22425 ENOG410680R Protein of unknown function (DUF2592) FNZ59_RS22430 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FNZ59_RS22435 ENOG4105E0C molybdate abc transporter FNZ59_RS22440 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) FNZ59_RS22445 ENOG4108K4B hydrolase FNZ59_RS22455 ENOG4105F04 LysR family Transcriptional regulator FNZ59_RS22460 ENOG4105C7F AcnD-accessory protein PrpF FNZ59_RS22465 ENOG4107QPK )-transporter FNZ59_RS22470 ENOG4107QM5 aconitate hydratase FNZ59_RS22475 ENOG4105NBR Pectinesterase FNZ59_RS22480 ENOG4108V1U phospholipid-binding protein FNZ59_RS22485 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FNZ59_RS22495 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FNZ59_RS22500 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FNZ59_RS22505 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FNZ59_RS22515 ENOG4105CHW UPF0052 protein FNZ59_RS22525 ENOG4108RIR Molybdenum cofactor biosynthesis protein FNZ59_RS22535 ENOG4105M00 molybdopterin converting factor, subunit 1 FNZ59_RS22540 ENOG4108ZAF Molybdopterin FNZ59_RS22545 ENOG4105HFZ Membrane FNZ59_RS22550 ENOG410733J conserved inner membrane protein FNZ59_RS22555 ENOG4107UXM Membrane FNZ59_RS22560 ENOG4105DZQ phospholipase D Transphosphatidylase FNZ59_RS22565 ENOG4105X23 Endonuclease Exonuclease phosphatase FNZ59_RS22570 ENOG4105I9U inner membrane protein ybhQ FNZ59_RS22575 ENOG4107QWP ABC-2 type transporter FNZ59_RS22580 ENOG4107QWP ABC-2 type transporter FNZ59_RS22585 ENOG4105CJ1 ABC, transporter FNZ59_RS22595 ENOG4107MVR Transcriptional regulator FNZ59_RS22600 ENOG4105C1J atp-dependent rna helicase FNZ59_RS22605 ENOG4108UV1 cellular component movement FNZ59_RS22610 ENOG4105DVT helicase FNZ59_RS22615 ENOG4108MTB glycosyl transferase family FNZ59_RS22620 ENOG4105DG4 malate L-lactate dehydrogenase FNZ59_RS22625 ENOG4105VR4 UPF0379 protein ybiJ FNZ59_RS22630 ENOG4105KSC Transcriptional regulator, TraR DksA family FNZ59_RS22640 ENOG4108IU3 tonb-dependent siderophore receptor FNZ59_RS22645 ENOG4105ZY9 UPF0379 protein ybiM FNZ59_RS22655 ENOG4105D8X mechanosensitive ion channel FNZ59_RS22660 ENOG4105CDA abc transporter atp-binding protein FNZ59_RS22665 ENOG4105E5Q amino acid AbC transporter FNZ59_RS22670 ENOG4107R0W ABC transporter FNZ59_RS22680 ENOG4107AQZ Membrane FNZ59_RS22690 ENOG4108T1M outer membrane protein x FNZ59_RS22695 ENOG4108I6E Sulfatase FNZ59_RS22705 ENOG4105KST dependent repressor FNZ59_RS22710 ENOG4105F4P )-transporter FNZ59_RS22715 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FNZ59_RS22720 ENOG4105C5H ABC transporter FNZ59_RS22725 ENOG41072TH Protein of unknown function (DUF1479) FNZ59_RS22730 ENOG4108HCJ Hydrolase FNZ59_RS22735 ENOG4105C6N Formate acetyltransferase FNZ59_RS22740 ENOG4105F1A Pyruvate formate-lyase FNZ59_RS22745 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FNZ59_RS22750 ENOG4105D06 uba thif-type nad fad binding protein FNZ59_RS22755 ENOG4105CVM Molybdenum cofactor synthesis domain protein FNZ59_RS22760 ENOG4105D44 asparaginase FNZ59_RS22765 ENOG4108JQ6 ABC transporter FNZ59_RS22770 ENOG4105DEF Extracellular solute-binding protein, family 5 FNZ59_RS22780 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FNZ59_RS22785 ENOG4105BZU Histidine kinase FNZ59_RS22790 ENOG41064RH membrane protein YliF FNZ59_RS22800 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway FNZ59_RS22805 ENOG4105D8V Glucose sorbosone dehydrogenase FNZ59_RS22810 ENOG4108TGY Glutathione S-transferase FNZ59_RS22815 ENOG4105DZ1 carboxypeptidase FNZ59_RS22820 ENOG4107FB0 transcriptional regulator DeoR family FNZ59_RS22825 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FNZ59_RS22830 ENOG4107QF7 multi-drug FNZ59_RS22840 ENOG4108HCJ Hydrolase FNZ59_RS22845 ENOG4106UW1 Major Facilitator superfamily FNZ59_RS22850 ENOG4108RFG Tetr family transcriptional regulator FNZ59_RS22865 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FNZ59_RS22870 ENOG4105UPP uncharacterized protein ydcA FNZ59_RS22880 ENOG4105MEH FNZ59_RS22905 ENOG4105KSC Transcriptional regulator, TraR DksA family FNZ59_RS22910 ENOG4105DFE Dna adenine methylase FNZ59_RS22915 ENOG4105VZ1 Replication Protein FNZ59_RS22945 ENOG4108US3 tail fiber assembly FNZ59_RS22960 ENOG4105ZTC transcriptional activator, Ogr delta FNZ59_RS22970 ENOG4105GWF inner membrane protein YbjM FNZ59_RS22975 ENOG41090BQ Glutaredoxin FNZ59_RS22980 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress FNZ59_RS22985 ENOG4108DBC nitroreductase FNZ59_RS22990 ENOG4108DBC nitroreductase FNZ59_RS23000 ENOG4108RMJ sensory transduction regulator FNZ59_RS23005 ENOG4107RUE extracellular solute-binding protein family 1 FNZ59_RS23010 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FNZ59_RS23015 ENOG4105F38 ABC transporter, permease FNZ59_RS23020 ENOG4105D38 putrescine abc transporter FNZ59_RS23025 ENOG4105RBQ inner membrane protein ybjO FNZ59_RS23035 ENOG4106TNF Periplasmic binding protein FNZ59_RS23040 ENOG4105DMR ABC, transporter FNZ59_RS23045 ENOG4105GBT ABC transporter FNZ59_RS23050 ENOG4106PMH Extracellular solute-binding protein family 3 FNZ59_RS23055 ENOG4105E5Z arginine transporter ATP-binding subunit FNZ59_RS23060 ENOG41064MM (LipO)protein FNZ59_RS23070 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FNZ59_RS23075 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FNZ59_RS23080 ENOG4105CGD Nad-dependent epimerase dehydratase FNZ59_RS23085 ENOG4105C5W Aldolase FNZ59_RS23090 ENOG4105C7K acetolactate synthase FNZ59_RS23095 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FNZ59_RS23105 ENOG4105DWU Membrane FNZ59_RS23110 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FNZ59_RS23115 ENOG4105CPB ATP-dependent endonuclease of the OLD family FNZ59_RS23120 ENOG4108MJ5 VirK protein FNZ59_RS23125 ENOG4105DJY efflux transporter, rnd family, mfp subunit FNZ59_RS23130 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FNZ59_RS23135 ENOG4105VEQ Cold shock protein FNZ59_RS23145 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FNZ59_RS23155 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FNZ59_RS23165 ENOG4108JJ8 (ABC) transporter FNZ59_RS23170 ENOG4108JJ9 ABC, transporter FNZ59_RS23175 ENOG4105C3M thioredoxin reductase FNZ59_RS23180 ENOG4105EW9 transcriptional regulator AsnC family FNZ59_RS23185 ENOG4105CNU cell division protein FtsK FNZ59_RS23195 ENOG4105D1H recombination factor protein RarA FNZ59_RS23205 ENOG4107QY8 reductase FNZ59_RS23210 ENOG4105QAX Iron-sulfur FNZ59_RS23215 ENOG4107KGK dmso reductase anchor subunit FNZ59_RS23220 ENOG4105CHJ isochorismatase hydrolase FNZ59_RS23230 ENOG4105E5D amino acid FNZ59_RS23235 ENOG410642W LysR family Transcriptional regulator FNZ59_RS23240 ENOG4108X0B nad(p)h dehydrogenase (quinone) FNZ59_RS23245 ENOG4105F1A Pyruvate formate-lyase FNZ59_RS23250 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FNZ59_RS23285 ENOG4106JVB Replication Protein FNZ59_RS23330 ENOG4108BUD transposase FNZ59_RS23345 ENOG4105C1P efflux transporter, rnd family, mfp subunit FNZ59_RS23400 ENOG4105CAU Arsenical resistance protein, ArsH FNZ59_RS23440 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A FNZ59_RS23460 ENOG4105W1Y Transcriptional regulator FNZ59_RS23465 ENOG4108VSE mercuric transport protein FNZ59_RS23495 ENOG4105BZU Histidine kinase FNZ59_RS23525 ENOG4105EMU Dehydrogenase FNZ59_RS23610 ENOG4108KTG Membrane protein, drug metabolite transporter FNZ59_RS23625 ENOG4105E3B Multicopper oxidase FNZ59_RS23635 ENOG4105DR5 peptidase FNZ59_RS23665 ENOG410624V efflux system protein FNZ59_RS23700 ENOG4105BZU Histidine kinase FNZ59_RS23745 ENOG4107QN2 dihydrolipoyl dehydrogenase FNZ59_RS23755 ENOG4108YXQ IS66 Orf2 family protein FNZ59_RS23775 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB FNZ59_RS23780 ENOG4105EZN Cobyrinic acid ac-diamide synthase FNZ59_RS23795 ENOG4106RMF ParB family FNZ59_RS23825 ENOG4105WI6 cell killing protein encoded within cryptic prophage FNZ59_RS23855 ENOG4108ZMA Outer membrane lipoprotein FNZ59_RS23860 ENOG41066DY Membrane FNZ59_RS23945 ENOG4108C33 Resolvase FNZ59_RS23995 ENOG4108UUM single-stranded DNA-binding protein FNZ59_RS24005 ENOG4105D7V transposase FNZ59_RS24140 ENOG4108R1E Serine threonine protein phosphatase 1 FNZ59_RS24200 ENOG4105CDU Replicative dna helicase FNZ59_RS24230 ENOG4105DFE Dna adenine methylase FNZ59_RS24305 ENOG4105K4U addiction module toxin, RelE StbE family