locus-tag class description HHJ27_RS00010 ENOG4105VZ1 Replication Protein HHJ27_RS00030 ENOG4105ED4 portal protein HHJ27_RS00120 ENOG4108US3 tail fiber assembly HHJ27_RS00170 ENOG4105ZTC transcriptional activator, Ogr delta HHJ27_RS00185 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HHJ27_RS00200 ENOG4105EBK exported protein HHJ27_RS00205 ENOG4108VTS Membrane HHJ27_RS00210 ENOG41065TG regulatoR HHJ27_RS00220 ENOG4105DP0 ferredoxin-NADP reductase HHJ27_RS00225 ENOG4105CBT Fructose-1,6-bisphosphatase HHJ27_RS00235 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ27_RS00250 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HHJ27_RS00265 ENOG41063M6 Cell Division Protein HHJ27_RS00270 ENOG4105ETE Transcriptional regulator (LacI family HHJ27_RS00275 ENOG4105C25 Primosomal protein n' HHJ27_RS00285 ENOG4105CNA YD repeat protein HHJ27_RS00295 ENOG410600T transposase HHJ27_RS00300 ENOG410600T transposase HHJ27_RS00305 ENOG410600T transposase HHJ27_RS00310 ENOG410600T transposase HHJ27_RS00315 ENOG410600T transposase HHJ27_RS00320 ENOG41079JQ Membrane HHJ27_RS00330 ENOG4105CNA YD repeat protein HHJ27_RS00345 ENOG4107S01 Repressor protein MetJ HHJ27_RS00355 ENOG4105C28 cystathionine HHJ27_RS00360 ENOG4105CFH Aspartokinase HHJ27_RS00370 ENOG4105CGH 5'-nucleotidase HHJ27_RS00375 ENOG4105SYT Methylenetetrahydrofolate reductase HHJ27_RS00385 ENOG4108Q5Y Membrane HHJ27_RS00390 ENOG4108XC3 NADH ubiquinone oxidoreductase HHJ27_RS00395 ENOG4105DCT glycerol dehydrogenase HHJ27_RS00400 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ27_RS00405 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ27_RS00410 ENOG4105DM4 PTS System HHJ27_RS00415 ENOG4108YRF PTS System HHJ27_RS00425 ENOG4108AHH pyruvate formate lyase II activase HHJ27_RS00430 ENOG4108XCZ PTS System HHJ27_RS00435 ENOG4106R3P AraC family transcriptional regulator HHJ27_RS00440 ENOG4105DIJ Phosphoethanolamine transferase HHJ27_RS00455 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HHJ27_RS00470 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ27_RS00475 ENOG4105E98 transcriptional regulator DeoR family HHJ27_RS00485 ENOG4105C2J ABC transporter HHJ27_RS00490 ENOG4105CNN ABC, transporter HHJ27_RS00495 ENOG4105F5R ABC transporter HHJ27_RS00500 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HHJ27_RS00505 ENOG4105CMG Carbohydrate kinase HHJ27_RS00530 ENOG4108I5G Major Facilitator superfamily HHJ27_RS00535 ENOG4105C5Q Transcriptional regulator HHJ27_RS00545 ENOG4105EJ2 Transcriptional regulator HHJ27_RS00550 ENOG4108Y73 Membrane HHJ27_RS00560 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) HHJ27_RS00590 ENOG4105D4A Cell wall formation (By similarity) HHJ27_RS00595 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HHJ27_RS00630 ENOG4105PM1 preprotein translocase subunit SecE HHJ27_RS00635 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HHJ27_RS00670 ENOG410645W Thiamin biosynthesis protein ThiH HHJ27_RS00675 ENOG4105D41 biosynthesis protein thiH HHJ27_RS00685 ENOG4105WHD thiamine biosynthesis protein ThiS HHJ27_RS00690 ENOG4105D06 uba thif-type nad fad binding protein HHJ27_RS00725 ENOG4105R2J Conserved Protein HHJ27_RS00735 ENOG4108T8B Protein of unknown function (DUF1481) HHJ27_RS00740 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HHJ27_RS00745 ENOG4105BZU Histidine kinase HHJ27_RS00750 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ27_RS00755 ENOG4105C12 Phosphoribosylglycinamide synthetase HHJ27_RS00785 ENOG4105K5X acetyltransferase HHJ27_RS00795 ENOG4107QP3 malate synthase g HHJ27_RS00800 ENOG4108I9X Isocitrate lyase HHJ27_RS00815 ENOG41069M3 Transcriptional regulator HHJ27_RS00820 ENOG4105C3R Methionine synthase HHJ27_RS00825 ENOG4105EAM Na Pi-cotransporter HHJ27_RS00835 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HHJ27_RS00840 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ27_RS00845 ENOG4105ETZ PTS System HHJ27_RS00850 ENOG4105KPI PTS system sorbose subfamily IIB component HHJ27_RS00855 ENOG4108XCU pts system HHJ27_RS00860 ENOG4105CHR reductase HHJ27_RS00865 ENOG4105DKT Transcriptional regulator HHJ27_RS00870 ENOG4105FE9 pseudouridine synthase HHJ27_RS00875 ENOG4108ZR5 Conserved Protein HHJ27_RS00880 ENOG4105CFH Aspartokinase HHJ27_RS00885 ENOG4107QP8 phosphohexose isomerase HHJ27_RS00895 ENOG4108MDC (LipO)protein HHJ27_RS00900 ENOG4108Q9C Periplasmic Protein HHJ27_RS00905 ENOG4105E3R (LipO)protein HHJ27_RS00920 ENOG4105EG2 ABC transporter, permease HHJ27_RS00925 ENOG4105D56 permease protein HHJ27_RS00930 ENOG4107FKK extracellular solute-binding protein family 1 HHJ27_RS00935 ENOG4108IJ9 (ABC) transporter HHJ27_RS00945 ENOG4107W52 maltose operon periplasmic protein HHJ27_RS00970 ENOG41080IJ Diacylglycerol kinase HHJ27_RS00980 ENOG4107R73 Mate efflux family protein HHJ27_RS00985 ENOG4105VDW Csbd family HHJ27_RS00990 ENOG4105MYN Zinc uptake regulation protein HHJ27_RS01000 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ27_RS01005 ENOG4105P4Z Phage shock protein G HHJ27_RS01010 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HHJ27_RS01015 ENOG4105CDU Replicative dna helicase HHJ27_RS01020 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ27_RS01025 ENOG4105CGF Aromatic amino acid aminotransferase HHJ27_RS01035 ENOG4105F0S class B acid phosphatase HHJ27_RS01040 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HHJ27_RS01045 ENOG4105MSB protein, conserved in bacteria HHJ27_RS01050 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HHJ27_RS01055 ENOG4108UUM single-stranded DNA-binding protein HHJ27_RS01060 ENOG4105PMV Membrane HHJ27_RS01065 ENOG4108M8H domain protein HHJ27_RS01070 ENOG4108W3Q Transcriptional regulator HHJ27_RS01075 ENOG4108Z4X TRANSCRIPTIONal HHJ27_RS01080 ENOG4105C7N Xanthine uracil vitamin C permease HHJ27_RS01085 ENOG4105EEQ Na H antiporter HHJ27_RS01100 ENOG41062QD Membrane HHJ27_RS01105 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ27_RS01115 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HHJ27_RS01120 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ27_RS01125 ENOG4105DVI reductase, NrfD HHJ27_RS01130 ENOG4108QKW cytochrome c-type biogenesis protein HHJ27_RS01140 ENOG4108W0S formate-dependent nitrite reductase complex HHJ27_RS01145 ENOG4105CK2 sodium dicarboxylate symporter HHJ27_RS01150 ENOG41082ND Uncharacterized protein yjcO HHJ27_RS01160 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ27_RS01165 ENOG4108MI0 Resistance protein HHJ27_RS01170 ENOG4105J12 Multidrug resistance protein mdtN HHJ27_RS01175 ENOG4106833 HHJ27_RS01180 ENOG4105EUZ Beta-lactamase domain protein HHJ27_RS01185 ENOG4108YZG isomerase HHJ27_RS01195 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HHJ27_RS01200 ENOG410849A acetyltransferase, (GNAT) family HHJ27_RS01210 ENOG4105FD8 phosphonate metabolism protein PhnM HHJ27_RS01215 ENOG4105HRV phosphonate c-p lyase system protein phnl HHJ27_RS01220 ENOG4105ENV phosphonate C-P lyase system protein PhnK HHJ27_RS01225 ENOG4105FT8 Phosphonate metabolism HHJ27_RS01230 ENOG4105EKV Phosphonate metabolism protein HHJ27_RS01235 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HHJ27_RS01240 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HHJ27_RS01245 ENOG4107RJJ Transcriptional regulator HHJ27_RS01255 ENOG4105EHI Phosphonate ABC transporter, periplasmic HHJ27_RS01260 ENOG4105D5T phosphonate abc transporter HHJ27_RS01265 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HHJ27_RS01270 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HHJ27_RS01275 ENOG4108F5E vimentin HHJ27_RS01280 ENOG4108YIV HHJ27_RS01285 ENOG4105CSH Transporter HHJ27_RS01295 ENOG4105ECM Sensor protein basS pmrB HHJ27_RS01300 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ27_RS01305 ENOG4105DIJ Phosphoethanolamine transferase HHJ27_RS01310 ENOG4105D5Q Arginine ornithine antiporter HHJ27_RS01315 ENOG4106ZGR Transcriptional regulator HHJ27_RS01320 ENOG4105CXN decarboxylase HHJ27_RS01325 ENOG4108K2B transcriptional regulator HHJ27_RS01330 ENOG4105F8D glycoside hydrolase family 4 HHJ27_RS01335 ENOG4105CT4 transporter HHJ27_RS01340 ENOG4108R5S membrane HHJ27_RS01345 ENOG4107GFK fumarate HHJ27_RS01350 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ27_RS01355 ENOG4108MRH transcriptional regulatory protein HHJ27_RS01360 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ27_RS01365 ENOG4105VR1 Pfam:DUF1271 HHJ27_RS01370 ENOG410830R acetyltransferase HHJ27_RS01385 ENOG4105CRK lysyL-tRNA synthetase HHJ27_RS01390 ENOG4105DUX Transporter HHJ27_RS01395 ENOG4105CXN decarboxylase HHJ27_RS01400 ENOG4105D5Q Arginine ornithine antiporter HHJ27_RS01405 ENOG4108M3R transcriptional activator CadC HHJ27_RS01415 ENOG4108SIC Transcriptional regulator HHJ27_RS01420 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) HHJ27_RS01430 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ27_RS01435 ENOG4108IJ0 Aspartate ammonia-lyase HHJ27_RS01440 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HHJ27_RS01445 ENOG4105DVH amino acid HHJ27_RS01460 ENOG4108ZVF (LipO)protein HHJ27_RS01465 ENOG4105MTB Uncharacterized protein YjeJ HHJ27_RS01470 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HHJ27_RS01480 ENOG4107PEH Entericidin EcnA/B family HHJ27_RS01485 ENOG4106BSU Entericidin B HHJ27_RS01490 ENOG4105KPY Small multidrug resistance protein HHJ27_RS01495 ENOG4105QNF Outer membrane lipoprotein HHJ27_RS01500 ENOG41066YJ Beta-lactamase HHJ27_RS01515 ENOG4105E33 succinate dehydrogenase HHJ27_RS01520 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ27_RS01530 ENOG4107SC7 Inner membrane transporter yjeM HHJ27_RS01535 ENOG4106CG8 Inner membrane protein YjeO HHJ27_RS01540 ENOG4105EGS Mechanosensitive ion channel HHJ27_RS01585 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HHJ27_RS01590 ENOG4105K8N protein family UPF0079, ATPase HHJ27_RS01595 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ27_RS01615 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HHJ27_RS01620 ENOG4107QJR hflk protein HHJ27_RS01625 ENOG4105EPW hflc protein HHJ27_RS01645 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HHJ27_RS01650 ENOG4105C2N RNA methyltransferase TrmH family group 3 HHJ27_RS01655 ENOG4105FUX Conserved Protein HHJ27_RS01660 ENOG4108P9J Phage shock protein A HHJ27_RS01665 ENOG4107VNS Protein of unknown function (DUF2491) HHJ27_RS01670 ENOG4105Z6B inner membrane protein yjfl HHJ27_RS01675 ENOG4108KXT Conserved Protein HHJ27_RS01680 ENOG4106032 Glutathionylspermidine synthase HHJ27_RS01685 ENOG4105CSU acyl-Coa dehydrogenase HHJ27_RS01690 ENOG4105S17 UPF0379 protein yjfN HHJ27_RS01695 ENOG4105WSB biofilm stress and motility protein A HHJ27_RS01700 ENOG4108MXZ Esterase HHJ27_RS01715 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HHJ27_RS01740 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ27_RS01745 ENOG4105KIT UPF0379 protein yjfY HHJ27_RS01760 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HHJ27_RS01785 ENOG4105D7V transposase HHJ27_RS01795 ENOG4105FHY Opacity-associated protein A HHJ27_RS01800 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ27_RS01805 ENOG4105C85 amino acid HHJ27_RS01815 ENOG4105DXC membrane HHJ27_RS01820 ENOG4105ECR NmrA family HHJ27_RS01825 ENOG4105KVH Transcriptional regulator HHJ27_RS01830 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HHJ27_RS01835 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HHJ27_RS01845 ENOG4108UUE Transcriptional regulator HHJ27_RS01850 ENOG41061GZ Protein of unknown function (DUF1107) HHJ27_RS01855 ENOG4105C37 (CBS) domain HHJ27_RS01865 ENOG4105CFU surface antigen HHJ27_RS01870 ENOG4105MA0 exported protein HHJ27_RS01875 ENOG4108ZHD aig2 family HHJ27_RS01880 ENOG41087RY SpoVT_AbrB HHJ27_RS01885 ENOG4105MZG transcriptional modulator of maze toxin, mazf HHJ27_RS01890 ENOG4105F0N pyrophosphate phospho-hydrolase HHJ27_RS01895 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HHJ27_RS01900 ENOG4105C2J ABC transporter HHJ27_RS01905 ENOG4107R9N ABC transporter HHJ27_RS01910 ENOG41062B0 ABC transporter, permease HHJ27_RS01920 ENOG4105DFU Cell wall formation (By similarity) HHJ27_RS01930 ENOG4105CMS peptidase U62, modulator of DNA gyrase HHJ27_RS01935 ENOG4108XVM Cytochrome b(562) HHJ27_RS01945 ENOG4105K4U addiction module toxin, RelE StbE family HHJ27_RS01950 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HHJ27_RS01955 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HHJ27_RS01960 ENOG4105CG3 alpha amylase, catalytic region HHJ27_RS01965 ENOG4105C5Y PTS System HHJ27_RS01970 ENOG4105D4X repressor HHJ27_RS01980 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HHJ27_RS01985 ENOG4105KME endoribonuclease L-psp HHJ27_RS02000 ENOG4107C93 pyrBI operon leader peptide HHJ27_RS02005 ENOG4108UQ8 endoribonuclease L-psp HHJ27_RS02010 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HHJ27_RS02015 ENOG4108XFH Transcriptional regulator HHJ27_RS02020 ENOG4105XEP YhcH YjgK YiaL family protein HHJ27_RS02035 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HHJ27_RS02040 ENOG4108MJ3 acetyltransferase HHJ27_RS02045 ENOG4108M3P Membrane HHJ27_RS02050 ENOG4108RS6 transposase HHJ27_RS02055 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HHJ27_RS02060 ENOG4105MYG DNA polymerase iii, chi subunit HHJ27_RS02070 ENOG4108M8S permease YjgP YjgQ family protein HHJ27_RS02075 ENOG4108K5H permease YjgP YjgQ family protein HHJ27_RS02080 ENOG4105D7A ATP-binding protein HHJ27_RS02085 ENOG4105K2J Transcriptional regulator HHJ27_RS02090 ENOG4105C6Z Gluconate HHJ27_RS02095 ENOG4105CHR reductase HHJ27_RS02100 ENOG4105CPQ Dehydrogenase HHJ27_RS02105 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HHJ27_RS02110 ENOG4105DQ4 alcohol dehydrogenase HHJ27_RS02125 ENOG4108I6E Sulfatase HHJ27_RS02135 ENOG4105JHE Major Facilitator Superfamily HHJ27_RS02140 ENOG4107RJ5 oxidoreductase HHJ27_RS02185 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HHJ27_RS02190 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HHJ27_RS02195 ENOG4105C9U ATP-dependent DNA helicase RecQ HHJ27_RS02215 ENOG4105C9U ATP-dependent DNA helicase RecQ HHJ27_RS02265 ENOG4105QEK Transcriptional regulator HHJ27_RS02275 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) HHJ27_RS02300 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HHJ27_RS02310 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HHJ27_RS02325 ENOG4105EDR glucose galactose transporter HHJ27_RS02335 ENOG4107FB0 transcriptional regulator DeoR family HHJ27_RS02380 ENOG4108P8R HHJ27_RS02390 ENOG4105F4K antigen 43 HHJ27_RS02400 ENOG4106H6R UPF0380 protein HHJ27_RS02405 ENOG4106549 Antirestriction protein HHJ27_RS02410 ENOG4108YGG dna repair protein HHJ27_RS02420 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ27_RS02440 ENOG4105DKT Transcriptional regulator HHJ27_RS02445 ENOG4105C6Z Gluconate HHJ27_RS02450 ENOG4105C01 Dihydroxy-acid dehydratase HHJ27_RS02455 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HHJ27_RS02460 ENOG4106P37 HTH-type transcriptional regulator YjhI HHJ27_RS02465 ENOG4108PQ7 sgc region transcriptional regulator HHJ27_RS02470 ENOG4108RK0 3-epimerase HHJ27_RS02475 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ27_RS02480 ENOG4106P19 photosystem i assembly btpa HHJ27_RS02485 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ27_RS02490 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ27_RS02495 ENOG4105CN9 Peptidase m42 family protein HHJ27_RS02505 ENOG4105DTA methyltransferase HHJ27_RS02510 ENOG41080VW acetyltransferase HHJ27_RS02515 ENOG4105YCT UPF0386 protein HHJ27_RS02535 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) HHJ27_RS02540 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria HHJ27_RS02545 ENOG4108W9T type 1 fimbriae regulatory protein HHJ27_RS02550 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off HHJ27_RS02555 ENOG4108RQP Major type 1 subunit fimbrin HHJ27_RS02560 ENOG4108S54 Fimbrial protein HHJ27_RS02565 ENOG4108NAE Fimbrial chaperone protein HHJ27_RS02570 ENOG4105CW0 outer membrane usher protein HHJ27_RS02575 ENOG4108SQA Fimbrial HHJ27_RS02580 ENOG4108T65 Fimbrial HHJ27_RS02585 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HHJ27_RS02590 ENOG4107EFN gluconate transport system permease 3 HHJ27_RS02600 ENOG4105DEI Mannitol dehydrogenase HHJ27_RS02605 ENOG4105C6F GntR Family Transcriptional Regulator HHJ27_RS02625 ENOG4107YNJ LysR family Transcriptional regulator HHJ27_RS02630 ENOG4105DYB Isoaspartyl dipeptidase HHJ27_RS02635 ENOG4108P2H Inner membrane protein YjiG HHJ27_RS02640 ENOG41074DU domain protein HHJ27_RS02650 ENOG4105CBP Major Facilitator HHJ27_RS02665 ENOG4105CIZ coA-substrate-specific enzyme activase HHJ27_RS02670 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HHJ27_RS02675 ENOG4106BRA Membrane HHJ27_RS02680 ENOG41083G8 Multidrug resistance protein MdtM HHJ27_RS02690 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HHJ27_RS02695 ENOG4106DIZ Domain of unknown function (DUF1127) HHJ27_RS02705 ENOG4105DZR Type I site-specific deoxyribonuclease HHJ27_RS02710 ENOG4105EKX Restriction modification system DNA (Specificity HHJ27_RS02715 ENOG4105CVR type I restriction-modification system HHJ27_RS02720 ENOG4106H3A restriction HHJ27_RS02735 ENOG4105CKI cobalamin synthesis protein HHJ27_RS02740 ENOG4105VCD cytoplasmic protein HHJ27_RS02745 ENOG4105D22 carbon starvation protein HHJ27_RS02750 ENOG4107UWN reductase HHJ27_RS02755 ENOG4105EFA 4-hydroxyphenylacetate HHJ27_RS02785 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase HHJ27_RS02790 ENOG4105C26 Dehydrogenase HHJ27_RS02795 ENOG4105ERH Fumarylacetoacetate hydrolase HHJ27_RS02800 ENOG4108V8F Transcriptional regulator, MarR family HHJ27_RS02805 ENOG4105C8Q Methyl-accepting chemotaxis HHJ27_RS02810 ENOG4108I5G Major Facilitator superfamily HHJ27_RS02815 ENOG410617M Transcriptional regulator HHJ27_RS02820 ENOG4105CPQ Dehydrogenase HHJ27_RS02830 ENOG4105RI1 glycoprotein receptor HHJ27_RS02835 ENOG4106CVF DNA replication protein HHJ27_RS02850 ENOG4105DWK Membrane HHJ27_RS02855 ENOG4108N8T regulatoR HHJ27_RS02860 ENOG4108T94 DNA-binding transcriptional activator BglJ HHJ27_RS02865 ENOG4108819 ferric iron reductase HHJ27_RS02870 ENOG4105YBH Protein of unknown function (DUF1435) HHJ27_RS02895 ENOG4108WPU DNA polymerase III subunit psi HHJ27_RS02900 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HHJ27_RS02905 ENOG4105PAD Hydrolase HHJ27_RS02915 ENOG4105K3G Periplasmic Protein HHJ27_RS02925 ENOG4108NRW Phospholipase, patatin family HHJ27_RS02930 ENOG4105EYA deoxyribonuclease HHJ27_RS02935 ENOG41076CZ activating enzyme HHJ27_RS02940 ENOG4105G0K glycine radical enzyme YjjI family HHJ27_RS02960 ENOG4105D3A purine nucleoside phosphorylase DeoD-type HHJ27_RS02965 ENOG4105EUP HipA domain protein HHJ27_RS02975 ENOG41062Z9 Membrane HHJ27_RS02980 ENOG4105EAC phosphoserine phosphatase HHJ27_RS02985 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HHJ27_RS02990 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HHJ27_RS03005 ENOG4105C5H ABC transporter HHJ27_RS03010 ENOG4107SC1 transglycosylase HHJ27_RS03020 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ27_RS03030 ENOG4105UEI Transcriptional Regulator AraC Family HHJ27_RS03035 ENOG4108RH0 Crea protein HHJ27_RS03040 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ27_RS03045 ENOG4105EB3 Histidine kinase HHJ27_RS03050 ENOG4105CT7 inner membrane cred family protein HHJ27_RS03055 ENOG41065U4 response regulator HHJ27_RS03060 ENOG410759A HHJ27_RS03065 ENOG4106FVC RNA methyltransferase HHJ27_RS03075 ENOG4105CFH Aspartokinase HHJ27_RS03085 ENOG4105D98 threonine synthase HHJ27_RS03090 ENOG41062C6 Protein of unknown function (DUF2502) HHJ27_RS03100 ENOG4105BZG amino acid carrier protein HHJ27_RS03110 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ27_RS03115 ENOG4106HK8 GPR1 FUN34 yaaH family protein HHJ27_RS03120 ENOG4108QUJ UPF0174 protein YaaW HHJ27_RS03140 ENOG4105WI6 cell killing protein encoded within cryptic prophage HHJ27_RS03150 ENOG41063Z6 transcriptional regulator, lysR family HHJ27_RS03160 ENOG4105CW0 outer membrane usher protein HHJ27_RS03190 ENOG4105CW0 outer membrane usher protein HHJ27_RS03195 ENOG4108MQF Chaperone HHJ27_RS03215 ENOG410647N response to DNA damage stimulus HHJ27_RS03220 ENOG4105DTN riboflavin biosynthesis protein ribF HHJ27_RS03235 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HHJ27_RS03250 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) HHJ27_RS03255 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HHJ27_RS03260 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HHJ27_RS03265 ENOG4108XNW Transcriptional activatory protein CaiF HHJ27_RS03270 ENOG4108Z0R Transferase HHJ27_RS03275 ENOG4106YT9 Enoyl-CoA hydratase HHJ27_RS03305 ENOG4105C10 Electron transfer flavoprotein HHJ27_RS03310 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ27_RS03315 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HHJ27_RS03320 ENOG4105C54 Major Facilitator superfamily HHJ27_RS03335 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HHJ27_RS03375 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HHJ27_RS03380 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HHJ27_RS03385 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HHJ27_RS03400 ENOG4105D3G Pseudouridine synthase HHJ27_RS03405 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HHJ27_RS03410 ENOG4105CQ2 DNA polymerase HHJ27_RS03415 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ27_RS03430 ENOG41063TF transcriptional regulator (AraC HHJ27_RS03435 ENOG4108KF1 Membrane HHJ27_RS03445 ENOG4106SMU thiamine transporter membrane protein HHJ27_RS03450 ENOG4105DP9 ABC transporter HHJ27_RS03460 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) HHJ27_RS03495 ENOG41064T2 transcriptional regulator, lysR family HHJ27_RS03505 ENOG4105C7K acetolactate synthase HHJ27_RS03510 ENOG4108ZP8 Acetolactate synthase small subunit HHJ27_RS03520 ENOG4107B7Y DNA-binding transcriptional regulator FruR HHJ27_RS03535 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HHJ27_RS03540 ENOG4105CJN penicillin-binding protein HHJ27_RS03545 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HHJ27_RS03550 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HHJ27_RS03560 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) HHJ27_RS03565 ENOG4105CNI cell division protein FtsW HHJ27_RS03580 ENOG4105CPF Cell wall formation (By similarity) HHJ27_RS03585 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HHJ27_RS03590 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HHJ27_RS03595 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HHJ27_RS03615 ENOG4105M6F mutator MutT protein HHJ27_RS03630 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HHJ27_RS03640 ENOG4105D7Q type ii secretion system HHJ27_RS03645 ENOG4107QHF type ii secretion system protein e HHJ27_RS03650 ENOG4108ZUW Major pilin subunit HHJ27_RS03655 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HHJ27_RS03660 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ27_RS03665 ENOG4106A72 regulatory protein AmpE HHJ27_RS03670 ENOG4105C85 amino acid HHJ27_RS03675 ENOG41073TP transcriptional regulator HHJ27_RS03680 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HHJ27_RS03685 ENOG4107QSN dihydrolipoamide acetyltransferase HHJ27_RS03690 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ27_RS03695 ENOG4108NST exported protein HHJ27_RS03700 ENOG4107QIJ Aconitate hydratase 2 HHJ27_RS03720 ENOG4108ZRK uncharacterized protein yacC HHJ27_RS03725 ENOG4105E3B Multicopper oxidase HHJ27_RS03730 ENOG4105DZG Dehydrogenase HHJ27_RS03735 ENOG4108UGV hypoxanthine phosphoribosyltransferase HHJ27_RS03740 ENOG41077A9 carbonic anhydrase HHJ27_RS03745 ENOG4105DA5 (ABC) transporter HHJ27_RS03750 ENOG4105E3A (ABC) transporter HHJ27_RS03755 ENOG4108YTN IIa component HHJ27_RS03760 ENOG4107BJW polysaccharide deacetylase HHJ27_RS03770 ENOG4108A32 Transposase HHJ27_RS03785 ENOG4105P0Q fimbrial-like protein YadC HHJ27_RS03790 ENOG4105SN2 fimbrial-like adhesin protein HHJ27_RS03795 ENOG4108XEY fimbrial-like adhesin protein HHJ27_RS03805 ENOG4108VEV chaperone HHJ27_RS03815 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HHJ27_RS03820 ENOG4105DJ0 Poly(A) Polymerase HHJ27_RS03825 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) HHJ27_RS03840 ENOG4107XID 2'-5' rna ligase HHJ27_RS03845 ENOG4105CQ7 ATP-dependent helicase HHJ27_RS03850 ENOG4105BZ4 penicillin-binding protein HHJ27_RS03855 ENOG4105E0K tonB-dependent siderophore receptor HHJ27_RS03860 ENOG4105E0A ABC, transporter HHJ27_RS03865 ENOG4105J76 Periplasmic binding protein HHJ27_RS03870 ENOG4105S6R Iron-hydroxamate transporter permease subunit HHJ27_RS03895 ENOG4105EN6 Membrane HHJ27_RS03900 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HHJ27_RS03915 ENOG4105C0H protease HHJ27_RS03920 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HHJ27_RS03940 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HHJ27_RS03965 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HHJ27_RS03970 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HHJ27_RS03975 ENOG4105KNE Phosphatidate cytidylyltransferase HHJ27_RS03980 ENOG4105DZP Membrane-associated zinc metalloprotease HHJ27_RS03990 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HHJ27_RS03995 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HHJ27_RS04010 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HHJ27_RS04015 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) HHJ27_RS04020 ENOG4105C0B DNA polymerase III (alpha subunit) HHJ27_RS04030 ENOG4105CXN decarboxylase HHJ27_RS04035 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HHJ27_RS04040 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HHJ27_RS04045 ENOG4105M1T rho-binding antiterminator HHJ27_RS04055 ENOG4108VWS Yaeq family HHJ27_RS04060 ENOG4108YZN class I peptide chain release factor HHJ27_RS04065 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HHJ27_RS04070 ENOG4108UY0 (LipO)protein HHJ27_RS04080 ENOG4108R96 Methyltransferase, YaeB family HHJ27_RS04085 ENOG4108R8X outer membrane lipoprotein HHJ27_RS04090 ENOG4105D01 (LipO)protein HHJ27_RS04095 ENOG4108UMI ABC transporter, permease HHJ27_RS04100 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS04105 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HHJ27_RS04140 ENOG4105CV8 reductase HHJ27_RS04145 ENOG4105HEI LysR family (Transcriptional regulator HHJ27_RS04155 ENOG4105F2W methyltransferase HHJ27_RS04160 ENOG4105E9H Lytic Murein transglycosylase HHJ27_RS04170 ENOG4105D1A Methyltransferase HHJ27_RS04180 ENOG4107RZZ dna polymerase iii epsilon subunit HHJ27_RS04190 ENOG410600K aminopeptidase HHJ27_RS04205 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ27_RS04230 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ27_RS04285 ENOG4108WC9 type VI secretion system effector, hcp1 family HHJ27_RS04290 ENOG4105CS6 Rhs element vgr protein HHJ27_RS04305 ENOG4107TV1 YD repeat protein HHJ27_RS04315 ENOG410600T transposase HHJ27_RS04325 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ27_RS04330 ENOG4108WN0 inhibitor of vertebrate lysozyme HHJ27_RS04335 ENOG4107QPN acyl-Coa dehydrogenase HHJ27_RS04345 ENOG4105E7A Glutamine amidotransferase HHJ27_RS04350 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HHJ27_RS04355 ENOG4108YS0 lipoprotein YafL HHJ27_RS04385 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system HHJ27_RS04390 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome HHJ27_RS04395 ENOG4108HYG acetyltransferase HHJ27_RS04405 ENOG4108S2Y peptide Chain Release factor HHJ27_RS04410 ENOG4105CIN aminoacyl-histidine dipeptidase HHJ27_RS04420 ENOG4105V1F Fermentation respiration switch protein HHJ27_RS04430 ENOG4105FCK Membrane HHJ27_RS04455 ENOG4105HVQ Regulatory factor of maltose metabolism HHJ27_RS04485 ENOG4105EQ2 LysR family Transcriptional regulator HHJ27_RS04490 ENOG4105ENX hydrolase HHJ27_RS04495 ENOG4107RTG Major Facilitator superfamily HHJ27_RS04500 ENOG4107XAN XdhC and CoxI family HHJ27_RS04505 ENOG4105C7W Xanthine dehydrogenase HHJ27_RS04510 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit HHJ27_RS04515 ENOG4105R3P Inner membrane protein yagU HHJ27_RS04520 ENOG4105PI0 Ferredoxin HHJ27_RS04530 ENOG4106PYX Receptor HHJ27_RS04545 ENOG4108GWT fimbrillin MatB HHJ27_RS04570 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ27_RS04575 ENOG4105ENX hydrolase HHJ27_RS04580 ENOG410642W LysR family Transcriptional regulator HHJ27_RS04585 ENOG4105EQ2 LysR family Transcriptional regulator HHJ27_RS04590 ENOG4107SET aldo keto reductase HHJ27_RS04610 ENOG4105CV8 reductase HHJ27_RS04615 ENOG4108KBJ Inner membrane protein YkgB HHJ27_RS04620 ENOG41066GK UPF0379 protein ykgI HHJ27_RS04625 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ27_RS04630 ENOG4108K01 transcriptional regulator HHJ27_RS04635 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ27_RS04640 ENOG4107QR9 Iron-sulfur cluster binding protein HHJ27_RS04645 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HHJ27_RS04670 ENOG4105C94 Transporter HHJ27_RS04675 ENOG4105BZU Histidine kinase HHJ27_RS04680 ENOG4108NUU Transcriptional regulator HHJ27_RS04685 ENOG4105SZ2 membrAne HHJ27_RS04690 ENOG4107SNB ankyrin repeat protein YahD HHJ27_RS04695 ENOG4105N16 Protein of unknown function (DUF2877) HHJ27_RS04700 ENOG4107R1Q Membrane protein FdrA HHJ27_RS04705 ENOG4107REC cytoplasmic protein HHJ27_RS04710 ENOG4105C5B carbamate kinase HHJ27_RS04715 ENOG4105DZC cytosine deaminase HHJ27_RS04725 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ27_RS04730 ENOG4105C2J ABC transporter HHJ27_RS04735 ENOG4105CNN ABC, transporter HHJ27_RS04740 ENOG4105CNN ABC, transporter HHJ27_RS04745 ENOG4105DQ4 alcohol dehydrogenase HHJ27_RS04760 ENOG4105E82 cytochrome subunit of dehydrogenase HHJ27_RS04765 ENOG4105TDT uncharacterized protein yahO HHJ27_RS04770 ENOG4108JU7 Transcriptional regulator HHJ27_RS04775 ENOG4105CR4 methylisocitrate lyase HHJ27_RS04780 ENOG4105BZN citrate synthase HHJ27_RS04785 ENOG4105DXD 2-methylcitrate dehydratase HHJ27_RS04790 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ27_RS04795 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HHJ27_RS04800 ENOG4105DZC cytosine deaminase HHJ27_RS04805 ENOG4105DND Transcriptional regulator HHJ27_RS04810 ENOG4107B2H carbonic anhydrase HHJ27_RS04820 ENOG4105DJ2 Major Facilitator Superfamily HHJ27_RS04825 ENOG4108UW5 maltose o-acetyltransferase HHJ27_RS04830 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HHJ27_RS04840 ENOG4105ETE Transcriptional regulator (LacI family HHJ27_RS04845 ENOG4108K2P TRANSCRIPTIONal HHJ27_RS04880 ENOG4108SC4 )-transporter HHJ27_RS04885 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HHJ27_RS04905 ENOG4105SRB Uncharacterized protein yaiO HHJ27_RS04915 ENOG4108PBI Polysaccharide metabolism HHJ27_RS04920 ENOG4107W19 lmbE family HHJ27_RS04925 ENOG4106FTQ Taurine ABC transporter, periplasmic HHJ27_RS04930 ENOG4108ETV ABC transporter HHJ27_RS04935 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HHJ27_RS04940 ENOG4105E2B Taurine dioxygenase HHJ27_RS04945 ENOG4105D52 delta-aminolevulinic acid dehydratase HHJ27_RS04955 ENOG4108PNB DNA-binding transcriptional regulator HHJ27_RS04960 ENOG4107R6D beta-lactam binding protein AmpH HHJ27_RS04965 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HHJ27_RS04970 ENOG4107QS8 (LipO)protein HHJ27_RS04975 ENOG4105FR5 inner membrane protein YaiY HHJ27_RS04980 ENOG4105UNH Membrane HHJ27_RS04985 ENOG4105CPF Cell wall formation (By similarity) HHJ27_RS05000 ENOG4105G6Z alkaline phosphatase HHJ27_RS05005 ENOG4105VIF phosphate starvation-inducible protein HHJ27_RS05010 ENOG4105BZU Histidine kinase HHJ27_RS05015 ENOG4105II7 pyrroline-5-carboxylate reductase HHJ27_RS05030 ENOG4105SS3 HHJ27_RS05035 ENOG4105HBA AroM protein HHJ27_RS05060 ENOG4105DKQ ROK family HHJ27_RS05065 ENOG4105F27 Major Facilitator HHJ27_RS05070 ENOG4105EYH Exonuclease HHJ27_RS05075 ENOG4107RH8 nuclease SbcCD subunit D HHJ27_RS05080 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ27_RS05085 ENOG4105BZU Histidine kinase HHJ27_RS05090 ENOG4105CWM branched-chain amino acid transport system II carrier protein HHJ27_RS05095 ENOG4108RS6 transposase HHJ27_RS05100 ENOG4105C85 amino acid HHJ27_RS05105 ENOG4107R28 alpha amylase, catalytic region HHJ27_RS05130 ENOG4105VIE preprotein translocase, subunit YajC HHJ27_RS05135 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ27_RS05140 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ27_RS05145 ENOG4105N1F Hnh endonuclease HHJ27_RS05150 ENOG4105DRB nucleoside-specific channel-forming protein HHJ27_RS05165 ENOG4105D7V transposase HHJ27_RS05180 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HHJ27_RS05185 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) HHJ27_RS05195 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HHJ27_RS05200 ENOG4108ZAI phosphatidylglycerophosphatase a HHJ27_RS05210 ENOG4105CPC Aldo Keto reductase HHJ27_RS05220 ENOG4105CTB Polyprenyl synthetase HHJ27_RS05230 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) HHJ27_RS05235 ENOG4107S0N DJ-1 family HHJ27_RS05240 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HHJ27_RS05250 ENOG4107RDB Major Facilitator HHJ27_RS05260 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HHJ27_RS05265 ENOG4105CCU oxidase (Subunit III) HHJ27_RS05270 ENOG4105BZ9 Cytochrome C oxidase, subunit I HHJ27_RS05275 ENOG4105E2S oxidase) subunit II HHJ27_RS05280 ENOG4105EYM Major Facilitator superfamily HHJ27_RS05285 ENOG4105IEY (LipO)protein HHJ27_RS05290 ENOG4105M85 Bola protein HHJ27_RS05310 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HHJ27_RS05315 ENOG4105K70 DNA-binding protein HHJ27_RS05320 ENOG4105EIN peptidylprolyl cis-trans isomerase HHJ27_RS05325 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HHJ27_RS05330 ENOG4108TGP Thioesterase superfamily protein HHJ27_RS05340 ENOG4108NFA extracellular solute-binding protein HHJ27_RS05350 ENOG4108RS6 transposase HHJ27_RS05355 ENOG4108XM1 transcriptional regulator AsnC family HHJ27_RS05360 ENOG4105BZ1 (ABC) transporter HHJ27_RS05365 ENOG4105BZ1 (ABC) transporter HHJ27_RS05370 ENOG4108YZA Nitrogen regulatory protein pii HHJ27_RS05375 ENOG4105BZU Histidine kinase HHJ27_RS05380 ENOG4105C29 acyl-CoA thioesterase HHJ27_RS05385 ENOG4108MNP Glycoprotein polysaccharide metabolism HHJ27_RS05390 ENOG41080UX Methyltransferase HHJ27_RS05400 ENOG4105KCV RNA signal recognition particle 4.5S RNA HHJ27_RS05405 ENOG41066DG (EAL) domain protein HHJ27_RS05410 ENOG4105GSJ Inner membrane protein ylaC HHJ27_RS05415 ENOG4108UW5 maltose o-acetyltransferase HHJ27_RS05420 ENOG4105KF5 hemolysin expression-modulating protein HHJ27_RS05425 ENOG4108UKR Biofilm formation regulator YbaJ HHJ27_RS05430 ENOG4105BZS acriflavin resistance protein HHJ27_RS05435 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ27_RS05440 ENOG4107XI7 Tetr family transcriptional regulator HHJ27_RS05445 ENOG4105EGS Mechanosensitive ion channel HHJ27_RS05450 ENOG4106428 Protein of unknown function (DUF2496) HHJ27_RS05455 ENOG4108URS primosomal replication protein n'' HHJ27_RS05460 ENOG4105WD1 Membrane HHJ27_RS05470 ENOG4107QMP dna polymerase iii subunits gamma and tau HHJ27_RS05505 ENOG4107RE1 Inosine-guanosine kinase HHJ27_RS05510 ENOG4105CKD glutathione-regulated potassium-efflux system protein HHJ27_RS05515 ENOG4105EU0 Major facilitator Superfamily HHJ27_RS05520 ENOG4105CGH 5'-nucleotidase HHJ27_RS05525 ENOG4108Z66 YbaK ebsC protein HHJ27_RS05530 ENOG4105MBR gumn family HHJ27_RS05535 ENOG4105C59 p-type ATPase HHJ27_RS05540 ENOG4105CSV Glutaminase HHJ27_RS05545 ENOG4107RY6 amino acid HHJ27_RS05565 ENOG4107QZV Type I secretion membrane fusion protein HHJ27_RS05590 ENOG4105G5H Membrane HHJ27_RS05595 ENOG4107QX8 SPFH domain, Band 7 family protein HHJ27_RS05600 ENOG41083J0 (ABC) transporter HHJ27_RS05605 ENOG4105C4B ABC transporter, permease HHJ27_RS05610 ENOG4107QR8 Thioredoxin HHJ27_RS05615 ENOG4105E1F short-chain dehydrogenase reductase HHJ27_RS05620 ENOG4108UJV acyl-CoA thioesterase i HHJ27_RS05625 ENOG4108I0Y (ABC) transporter HHJ27_RS05630 ENOG4105CV6 ABC transporter, permease HHJ27_RS05640 ENOG4107653 Transcriptional regulator HHJ27_RS05650 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region HHJ27_RS05655 ENOG41060W2 glyoxylate carboligase HHJ27_RS05660 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ27_RS05665 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ27_RS05670 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HHJ27_RS05675 ENOG4105CD3 dihydroorotase HHJ27_RS05680 ENOG4105DTE Xanthine uracil vitamin C permease HHJ27_RS05685 ENOG4105BZW Glycerate kinase HHJ27_RS05690 ENOG4105S0E allantoin catabolism protein HHJ27_RS05695 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HHJ27_RS05700 ENOG4105DG4 malate L-lactate dehydrogenase HHJ27_RS05705 ENOG4107R1Q Membrane protein FdrA HHJ27_RS05710 ENOG4107REC cytoplasmic protein HHJ27_RS05715 ENOG4105G5A Protein of unknown function (DUF2877) HHJ27_RS05720 ENOG4105C5B carbamate kinase HHJ27_RS05725 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HHJ27_RS05730 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HHJ27_RS05740 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ27_RS05750 ENOG4105S2T inner membrane protein YbcI HHJ27_RS05755 ENOG4105WQ3 Rna-binding protein HHJ27_RS05765 ENOG4108WDE Fimbrial protein HHJ27_RS05770 ENOG4108AF8 Chaperone HHJ27_RS05775 ENOG4105CW0 outer membrane usher protein HHJ27_RS05780 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) HHJ27_RS05785 ENOG4108ZI2 Fimbrial protein HHJ27_RS05790 ENOG4108Q9V regulatoR HHJ27_RS05805 ENOG4105QUW HHJ27_RS05810 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HHJ27_RS05815 ENOG410802X bacteriophage n4 adsorption protein b HHJ27_RS05820 ENOG410600T transposase HHJ27_RS05835 ENOG4105CNA YD repeat protein HHJ27_RS05845 ENOG4105CS6 Rhs element vgr protein HHJ27_RS05850 ENOG4105GR3 Histidine kinase HHJ27_RS05855 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ27_RS05860 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HHJ27_RS05865 ENOG410624V efflux system protein HHJ27_RS05870 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HHJ27_RS05875 ENOG4108IJF Heavy metal efflux pump, CzcA HHJ27_RS05880 ENOG4105C85 amino acid HHJ27_RS05885 ENOG4105CUY Mechanosensitive ion channel HHJ27_RS05890 ENOG4108RCM Nitroreductase HHJ27_RS05895 ENOG4105MSB protein, conserved in bacteria HHJ27_RS05900 ENOG4105WQ6 Membrane HHJ27_RS05920 ENOG4108TSE Transferase HHJ27_RS05925 ENOG4107RNH Outer membrane receptor FepA HHJ27_RS05930 ENOG4105E93 esterase HHJ27_RS05935 ENOG41085A6 mbth domain-containing protein HHJ27_RS05940 ENOG4105C0W non-ribosomal peptide synthetase HHJ27_RS05945 ENOG4108QY5 Ferric enterobactin transport protein HHJ27_RS05950 ENOG4105E0A ABC, transporter HHJ27_RS05955 ENOG4105TVJ transport system, permease HHJ27_RS05960 ENOG4105DQ5 transport system permease protein HHJ27_RS05970 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HHJ27_RS05975 ENOG4105E4F Isochorismate synthase HHJ27_RS05980 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HHJ27_RS05985 ENOG4105WQI isochorismatase HHJ27_RS05990 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HHJ27_RS05995 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HHJ27_RS06000 ENOG4105D22 carbon starvation protein HHJ27_RS06005 ENOG4105VCD cytoplasmic protein HHJ27_RS06010 ENOG4107SCQ Iron-containing alcohol dehydrogenase HHJ27_RS06015 ENOG4105CHM Aminotransferase HHJ27_RS06020 ENOG4105GTN ParB Domain Protein Nuclease HHJ27_RS06030 ENOG4105DQS Transcriptional regulator HHJ27_RS06035 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HHJ27_RS06040 ENOG4105D3R alkyl hydroperoxide reductase HHJ27_RS06045 ENOG4108JU3 Alkyl hydroperoxide reductase HHJ27_RS06050 ENOG4108U51 Universal stress protein HHJ27_RS06055 ENOG4105NXH GreA GreB family elongation factor HHJ27_RS06060 ENOG4105KTS ribonuclease HHJ27_RS06065 ENOG4107QPK )-transporter HHJ27_RS06080 ENOG4105CHY citrate lyase, alpha HHJ27_RS06085 ENOG4105CI0 Citrate lyase HHJ27_RS06095 ENOG4105DUA (citrate (pro-3S)-lyase ligase HHJ27_RS06100 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ27_RS06105 ENOG4106YYS transcriptional regulatory protein HHJ27_RS06110 ENOG4105CEE C4-dicarboxylate transporter HHJ27_RS06115 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) HHJ27_RS06135 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HHJ27_RS06145 ENOG41064T2 transcriptional regulator, lysR family HHJ27_RS06160 ENOG4105DZ1 carboxypeptidase HHJ27_RS06165 ENOG4105K6T rare lipoprotein A HHJ27_RS06170 ENOG4105CNI cell division protein FtsW HHJ27_RS06175 ENOG4105CJN penicillin-binding protein HHJ27_RS06185 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HHJ27_RS06190 ENOG4108TGR phosphatase HHJ27_RS06200 ENOG4105DJF DNA polymerase III, delta' subunit HHJ27_RS06215 ENOG4107PAI alpha helical protein HHJ27_RS06225 ENOG4105CDA abc transporter atp-binding protein HHJ27_RS06230 ENOG4105DRP amino acid AbC transporter HHJ27_RS06235 ENOG4105EAD ABC transporter HHJ27_RS06240 ENOG4107RP9 extracellular solute-binding protein, family 3 HHJ27_RS06245 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HHJ27_RS06250 ENOG4108JU5 Magnesium and cobalt efflux protein HHJ27_RS06260 ENOG4105C9A Phoh family HHJ27_RS06270 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ27_RS06310 ENOG4105CAQ asparagine synthetase HHJ27_RS06315 ENOG4105D4U had-superfamily hydrolase, subfamily iia HHJ27_RS06320 ENOG4105E2R ROK family HHJ27_RS06325 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ27_RS06335 ENOG4105CI1 PTS System HHJ27_RS06350 ENOG4105GX6 (LipO)protein HHJ27_RS06355 ENOG41090R7 Ferric uptake HHJ27_RS06365 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HHJ27_RS06370 ENOG4105NNH LexA regulated protein HHJ27_RS06375 ENOG4105EV9 Alpha Beta Hydrolase HHJ27_RS06380 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HHJ27_RS06385 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HHJ27_RS06390 ENOG4105D5Q Arginine ornithine antiporter HHJ27_RS06395 ENOG4105CXN decarboxylase HHJ27_RS06405 ENOG4105EEX Two component transcriptional regulator (Winged helix family HHJ27_RS06410 ENOG4105C08 Histidine kinase HHJ27_RS06435 ENOG4105XIQ Protein of unknown function (DUF2517) HHJ27_RS06440 ENOG4105CNA YD repeat protein HHJ27_RS06450 ENOG4105CNA YD repeat protein HHJ27_RS06460 ENOG4107SEY Conserved Protein HHJ27_RS06465 ENOG4105CVP deoxyribo-dipyrimidine photolyase HHJ27_RS06470 ENOG4105DUX Transporter HHJ27_RS06475 ENOG4107QNR UPF0135 protein HHJ27_RS06480 ENOG4105P4J Allophanate hydrolase, subunit 1 HHJ27_RS06485 ENOG4107R7A Allophanate hydrolase subunit 2 HHJ27_RS06500 ENOG4108KK1 membrane protein AbrB duplication HHJ27_RS06505 ENOG4108MY7 Fimbrial HHJ27_RS06510 ENOG4108TTM chaperone HHJ27_RS06515 ENOG4106PG1 outer membrane usher protein HHJ27_RS06520 ENOG4106UBK fimbrial-like adhesin protein HHJ27_RS06525 ENOG4105BZN citrate synthase HHJ27_RS06535 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HHJ27_RS06540 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HHJ27_RS06545 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ27_RS06550 ENOG4105E33 succinate dehydrogenase HHJ27_RS06555 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HHJ27_RS06560 ENOG4105C7S Dehydrogenase HHJ27_RS06570 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HHJ27_RS06575 ENOG4105ETT transcriptional Regulator, LysR family HHJ27_RS06580 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HHJ27_RS06585 ENOG4107GFK fumarate HHJ27_RS06610 ENOG4105DJI Methylaspartate mutase, E subunit HHJ27_RS06620 ENOG4107WFU Glutamate mutase subunit sigma HHJ27_RS06635 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ27_RS06640 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ27_RS06650 ENOG4105KJB cyd operon protein YbgE HHJ27_RS06655 ENOG4107YD3 Thioesterase HHJ27_RS06660 ENOG4105E02 MotA TolQ exbB proton channel HHJ27_RS06670 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HHJ27_RS06680 ENOG4105KCK Peptidoglycan-associated lipoprotein HHJ27_RS06685 ENOG4105UFD tol-pal system protein YbgF HHJ27_RS06725 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) HHJ27_RS06730 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HHJ27_RS06735 ENOG4105PGM cation diffusion facilitator family transporter HHJ27_RS06740 ENOG4105JND homeobox protein HHJ27_RS06745 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ27_RS06755 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HHJ27_RS06765 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HHJ27_RS06770 ENOG4105CMR udp-glucose 4-epimerase HHJ27_RS06775 ENOG4105DKW ABC transporter HHJ27_RS06780 ENOG4105F4R Transcriptional regulator mode HHJ27_RS06790 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HHJ27_RS06795 ENOG4105E0C molybdate abc transporter HHJ27_RS06800 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS06805 ENOG4108K4B hydrolase HHJ27_RS06815 ENOG4105F04 LysR family Transcriptional regulator HHJ27_RS06820 ENOG4105C7F AcnD-accessory protein PrpF HHJ27_RS06825 ENOG4107QPK )-transporter HHJ27_RS06830 ENOG4107QM5 aconitate hydratase HHJ27_RS06835 ENOG4105NBR Pectinesterase HHJ27_RS06840 ENOG4108I1J Integrase HHJ27_RS06895 ENOG41077V0 CPS-53 (KpLE1) prophage HHJ27_RS06920 ENOG4108PNI recT protein HHJ27_RS06975 ENOG4105CDU Replicative dna helicase HHJ27_RS07020 ENOG4105RWQ Protein of unknown function (DUF1364) HHJ27_RS07050 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HHJ27_RS07060 ENOG4106050 phage regulatory protein, rha family HHJ27_RS07075 ENOG4108N0N Phage Terminase Large Subunit HHJ27_RS07155 ENOG4108V1U phospholipid-binding protein HHJ27_RS07160 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HHJ27_RS07175 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HHJ27_RS07180 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ27_RS07190 ENOG4105CHW UPF0052 protein HHJ27_RS07200 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ27_RS07210 ENOG4105M00 molybdopterin converting factor, subunit 1 HHJ27_RS07215 ENOG4108ZAF Molybdopterin HHJ27_RS07220 ENOG4105HFZ Membrane HHJ27_RS07225 ENOG410733J conserved inner membrane protein HHJ27_RS07230 ENOG4107UXM Membrane HHJ27_RS07235 ENOG4105DZQ phospholipase D Transphosphatidylase HHJ27_RS07240 ENOG4105X23 Endonuclease Exonuclease phosphatase HHJ27_RS07245 ENOG4105I9U inner membrane protein ybhQ HHJ27_RS07250 ENOG4107QWP ABC-2 type transporter HHJ27_RS07255 ENOG4107QWP ABC-2 type transporter HHJ27_RS07260 ENOG4105CJ1 ABC, transporter HHJ27_RS07270 ENOG4107MVR Transcriptional regulator HHJ27_RS07275 ENOG4105C1J atp-dependent rna helicase HHJ27_RS07290 ENOG4105DVT helicase HHJ27_RS07295 ENOG4108MTB glycosyl transferase family HHJ27_RS07300 ENOG4105DG4 malate L-lactate dehydrogenase HHJ27_RS07305 ENOG4105VR4 UPF0379 protein ybiJ HHJ27_RS07310 ENOG4105KSC Transcriptional regulator, TraR DksA family HHJ27_RS07320 ENOG4108ESX Receptor HHJ27_RS07325 ENOG4105ZY9 UPF0379 protein ybiM HHJ27_RS07335 ENOG4105D8X mechanosensitive ion channel HHJ27_RS07340 ENOG4105CDA abc transporter atp-binding protein HHJ27_RS07345 ENOG4105E5Q amino acid AbC transporter HHJ27_RS07350 ENOG4107R0W ABC transporter HHJ27_RS07360 ENOG4107AQZ Membrane HHJ27_RS07370 ENOG4108T1M outer membrane protein x HHJ27_RS07375 ENOG4108I6E Sulfatase HHJ27_RS07385 ENOG4105KST dependent repressor HHJ27_RS07390 ENOG4105F4P )-transporter HHJ27_RS07395 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ27_RS07400 ENOG4105C5H ABC transporter HHJ27_RS07410 ENOG4105DPW Major facilitator superfamily MFS_1 HHJ27_RS07415 ENOG4105ETE Transcriptional regulator (LacI family HHJ27_RS07420 ENOG41072TH Protein of unknown function (DUF1479) HHJ27_RS07425 ENOG4108HCJ Hydrolase HHJ27_RS07435 ENOG4105F1A Pyruvate formate-lyase HHJ27_RS07440 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ27_RS07445 ENOG4105D06 uba thif-type nad fad binding protein HHJ27_RS07450 ENOG4105CVM Molybdenum cofactor synthesis domain protein HHJ27_RS07455 ENOG4105D44 asparaginase HHJ27_RS07460 ENOG4108JQ6 ABC transporter HHJ27_RS07465 ENOG4105DEF Extracellular solute-binding protein, family 5 HHJ27_RS07480 ENOG4105BZU Histidine kinase HHJ27_RS07485 ENOG41064RH membrane protein YliF HHJ27_RS07505 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HHJ27_RS07510 ENOG4105D8V Glucose sorbosone dehydrogenase HHJ27_RS07515 ENOG4108TGY Glutathione S-transferase HHJ27_RS07520 ENOG4105DZ1 carboxypeptidase HHJ27_RS07525 ENOG4107FB0 transcriptional regulator DeoR family HHJ27_RS07530 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HHJ27_RS07535 ENOG4107QF7 multi-drug HHJ27_RS07545 ENOG4108HCJ Hydrolase HHJ27_RS07550 ENOG4106UW1 Major Facilitator superfamily HHJ27_RS07555 ENOG4108RFG Tetr family transcriptional regulator HHJ27_RS07565 ENOG4105GWF inner membrane protein YbjM HHJ27_RS07570 ENOG41090BQ Glutaredoxin HHJ27_RS07575 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HHJ27_RS07580 ENOG4108DBC nitroreductase HHJ27_RS07590 ENOG4108RMJ sensory transduction regulator HHJ27_RS07595 ENOG4107RUE extracellular solute-binding protein family 1 HHJ27_RS07600 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS07605 ENOG4105F38 ABC transporter, permease HHJ27_RS07610 ENOG4105D38 putrescine abc transporter HHJ27_RS07615 ENOG4105RBQ inner membrane protein ybjO HHJ27_RS07625 ENOG4106TNF Periplasmic binding protein HHJ27_RS07630 ENOG4105DMR ABC, transporter HHJ27_RS07635 ENOG4105GBT ABC transporter HHJ27_RS07640 ENOG4106PMH Extracellular solute-binding protein family 3 HHJ27_RS07645 ENOG4105E5Z arginine transporter ATP-binding subunit HHJ27_RS07650 ENOG41064MM (LipO)protein HHJ27_RS07665 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ27_RS07670 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HHJ27_RS07675 ENOG4105CGD Nad-dependent epimerase dehydratase HHJ27_RS07680 ENOG4105C5W Aldolase HHJ27_RS07685 ENOG4105C7K acetolactate synthase HHJ27_RS07690 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ27_RS07700 ENOG4105DWU Membrane HHJ27_RS07705 ENOG4105EQR Transposase IS116 IS110 IS902 HHJ27_RS07710 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ27_RS07715 ENOG4105CPB ATP-dependent endonuclease of the OLD family HHJ27_RS07720 ENOG4108MJ5 VirK protein HHJ27_RS07725 ENOG4105DJY efflux transporter, rnd family, mfp subunit HHJ27_RS07735 ENOG4105VEQ Cold shock protein HHJ27_RS07745 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ27_RS07760 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HHJ27_RS07770 ENOG4108JJ8 (ABC) transporter HHJ27_RS07775 ENOG4108JJ9 ABC, transporter HHJ27_RS07780 ENOG4105C3M thioredoxin reductase HHJ27_RS07790 ENOG4105CNU cell division protein FtsK HHJ27_RS07800 ENOG4105D1H recombination factor protein RarA HHJ27_RS07810 ENOG4107QY8 reductase HHJ27_RS07815 ENOG4105QAX Iron-sulfur HHJ27_RS07820 ENOG4107KGK dmso reductase anchor subunit HHJ27_RS07825 ENOG4105CHJ isochorismatase hydrolase HHJ27_RS07835 ENOG4105E5D amino acid HHJ27_RS07845 ENOG4105F1A Pyruvate formate-lyase HHJ27_RS07850 ENOG4105C6N Formate acetyltransferase HHJ27_RS07855 ENOG4105TMB Formate nitrite transporter HHJ27_RS07860 ENOG4105DDY UPF0142 protein ycaO HHJ27_RS07865 ENOG4107VMU Membrane HHJ27_RS07880 ENOG4108K0D peptidase, M48 HHJ27_RS07890 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HHJ27_RS07900 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HHJ27_RS07905 ENOG4105BZ1 (ABC) transporter HHJ27_RS07915 ENOG4105T0Z Conserved Protein HHJ27_RS07930 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HHJ27_RS07935 ENOG4107S90 membrAne HHJ27_RS07940 ENOG4106371 Methyltransferase HHJ27_RS07950 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HHJ27_RS07960 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HHJ27_RS07965 ENOG4105EAQ (twin-arginine translocation) pathway signal HHJ27_RS07970 ENOG4105C5X domain protein HHJ27_RS07975 ENOG4105CGF Aromatic amino acid aminotransferase HHJ27_RS07980 ENOG4105FCK Membrane HHJ27_RS07995 ENOG4105CD8 aminopeptidase N HHJ27_RS08000 ENOG4105E2Y ABC, transporter HHJ27_RS08005 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HHJ27_RS08015 ENOG4105GVF (ABC) transporter HHJ27_RS08020 ENOG4108UZX fmn reductase HHJ27_RS08025 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon HHJ27_RS08030 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae HHJ27_RS08035 ENOG4105CW0 outer membrane usher protein HHJ27_RS08040 ENOG4108MDY Fimbrial HHJ27_RS08045 ENOG4105Q7J Fimbrial HHJ27_RS08050 ENOG4105MX3 Fimbrial HHJ27_RS08055 ENOG4106PH7 chaperone HHJ27_RS08065 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HHJ27_RS08070 ENOG4105QVC MOSC domain-containing protein HHJ27_RS08080 ENOG4105C5H ABC transporter HHJ27_RS08085 ENOG4105F1S paraquat-inducible protein a HHJ27_RS08090 ENOG4105DY2 Paraquat-inducible protein b HHJ27_RS08095 ENOG4108Q2G (LipO)protein HHJ27_RS08100 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HHJ27_RS08110 ENOG4105DAN ATP-dependent protease HHJ27_RS08120 ENOG4105UYK outer membrane protein a HHJ27_RS08130 ENOG4108RZ1 DNA transformation protein HHJ27_RS08135 ENOG4105EM2 membrane HHJ27_RS08140 ENOG410901E Membrane HHJ27_RS08145 ENOG41088T4 Helicase IV HHJ27_RS08160 ENOG4105K4P CoA-binding domain protein HHJ27_RS08175 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HHJ27_RS08180 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HHJ27_RS08185 ENOG4108MN8 Membrane HHJ27_RS08195 ENOG4105E3S small subunit HHJ27_RS08200 ENOG4105DPX Hydrogenase, large subunit HHJ27_RS08205 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HHJ27_RS08210 ENOG4108USZ hydrogenase HHJ27_RS08215 ENOG4108VXY Hydrogenase-1 operon protein HyaE HHJ27_RS08220 ENOG4105MVP hydrogenase-1 operon protein HyaF HHJ27_RS08225 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ27_RS08230 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ27_RS08240 ENOG4105D6F Phosphatase HHJ27_RS08245 ENOG41060EU Cold shock-like protein HHJ27_RS08250 ENOG4105VEQ Cold shock protein HHJ27_RS08265 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HHJ27_RS08270 ENOG4105HEE Binding Domain protein HHJ27_RS08275 ENOG4105BZU Histidine kinase HHJ27_RS08280 ENOG4108SV3 Tmao reductase system periplasmic protein tort HHJ27_RS08285 ENOG4106WF9 DNA-binding transcriptional regulator TorR HHJ27_RS08290 ENOG4105CUW cytochrome C-TYPE protein HHJ27_RS08295 ENOG4108J2R molybdopterin oxidoreductase HHJ27_RS08320 ENOG4105D6F Phosphatase HHJ27_RS08325 ENOG4105XH3 HHJ27_RS08335 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HHJ27_RS08340 ENOG4105C2W permease HHJ27_RS08370 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) HHJ27_RS08375 ENOG4108R86 Transcriptional regulator HHJ27_RS08380 ENOG4105C26 Dehydrogenase HHJ27_RS08390 ENOG4105CK7 Sodium proline symporter HHJ27_RS08400 ENOG410650H (LipO)protein HHJ27_RS08410 ENOG4105D5M phosphate starvation-inducible protein HHJ27_RS08420 ENOG4105CND Glycosyl transferase, family 2 HHJ27_RS08425 ENOG4107BJW polysaccharide deacetylase HHJ27_RS08430 ENOG4108TUY outer membrane protein PgaA HHJ27_RS08435 ENOG4105BZU Histidine kinase HHJ27_RS08445 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase HHJ27_RS08455 ENOG4107XHZ cytoplasmic chaperone TorD family protein HHJ27_RS08460 ENOG4108UQ5 membrane protein YcdZ HHJ27_RS08465 ENOG4105P8Q Curli production assembly transport component CsgG HHJ27_RS08470 ENOG4108WYR Curli production assembly transport component, CsgF HHJ27_RS08475 ENOG4108XDW curli assembly protein CsgE HHJ27_RS08480 ENOG41086KC Transcriptional regulator HHJ27_RS08485 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HHJ27_RS08490 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HHJ27_RS08505 ENOG4108UVJ appr-1-p processing domain protein HHJ27_RS08510 ENOG4107RZC phospholipase d HHJ27_RS08525 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HHJ27_RS08530 ENOG4108RS6 transposase HHJ27_RS08535 ENOG4105NAC (LipO)protein HHJ27_RS08540 ENOG4108W47 Acidic protein msyB HHJ27_RS08550 ENOG4105D1S lipid A biosynthesis HHJ27_RS08565 ENOG4105DS1 cytochrome b561 HHJ27_RS08570 ENOG4106974 biofilm formation HHJ27_RS08575 ENOG4105F76 Sarcosine oxidase HHJ27_RS08580 ENOG4105PVA Biofilm formation regulatory protein BssS HHJ27_RS08585 ENOG4105MEA DNA damage-inducible protein i HHJ27_RS08595 ENOG4105F3T (LipO)protein HHJ27_RS08600 ENOG4105E9S glutaredoxin 2 HHJ27_RS08610 ENOG4105D9U N-acetyltransferase HHJ27_RS08620 ENOG4105EP9 oxidoreductase HHJ27_RS08625 ENOG4105CJR Integral membrane protein (MviN HHJ27_RS08630 ENOG4105QVD Flagella synthesis protein FlgN HHJ27_RS08635 ENOG4105M9M anti-sigma28 factor FlgM HHJ27_RS08640 ENOG4105CKS Flagella basal body P-ring formation protein flgA HHJ27_RS08645 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HHJ27_RS08650 ENOG4108ZC9 flagellar basal-body rod protein flgc HHJ27_RS08655 ENOG4105W00 Flagellar hook capping protein HHJ27_RS08660 ENOG4105BZE flagellar hook protein, FlgE HHJ27_RS08665 ENOG4108KPB Flagellar basal-body rod protein FlgF HHJ27_RS08670 ENOG4105CGA flagellar basal-body rod protein FlgG HHJ27_RS08680 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) HHJ27_RS08685 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HHJ27_RS08690 ENOG4105E1Q flagellar hook-associated protein HHJ27_RS08695 ENOG4105DTJ flagellar hook-associated protein HHJ27_RS08710 ENOG4107QQB Ribonuclease E HHJ27_RS08715 ENOG4105EI2 Pseudouridine synthase HHJ27_RS08720 ENOG4108UHJ MAF-like protein HHJ27_RS08725 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HHJ27_RS08745 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HHJ27_RS08750 ENOG4105CHR reductase HHJ27_RS08755 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ27_RS08760 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ27_RS08765 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HHJ27_RS08770 ENOG4105HHA aminodeoxychorismate lyase HHJ27_RS08780 ENOG4107QRG dna polymerase iii HHJ27_RS08785 ENOG4105F8V Hydrolase, tatD family HHJ27_RS08790 ENOG4105CI1 PTS System HHJ27_RS08795 ENOG4105CNM Receptor HHJ27_RS08800 ENOG4105K59 histidine triad (HIT) protein HHJ27_RS08805 ENOG41090DQ Lipoprotein HHJ27_RS08810 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HHJ27_RS08830 ENOG4105CEP NADH dehydrogenase HHJ27_RS08835 ENOG4107MBR 17 kDa surface antigen HHJ27_RS08840 ENOG4108IND Tetr family transcriptional regulator HHJ27_RS08845 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HHJ27_RS08850 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ27_RS08855 ENOG4108JA2 transcriptioN-repair coupling factor HHJ27_RS08860 ENOG4105IQC Inner membrane protein YcfT HHJ27_RS08865 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ27_RS08870 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HHJ27_RS08875 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ27_RS08885 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HHJ27_RS08900 ENOG4107RUE extracellular solute-binding protein family 1 HHJ27_RS08905 ENOG4105D38 putrescine abc transporter HHJ27_RS08915 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS08925 ENOG4105EZE Cupin 4 family protein HHJ27_RS08930 ENOG4105IFJ Histidine kinase HHJ27_RS08935 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ27_RS08940 ENOG4107QTF adenylosuccinate lyase HHJ27_RS08960 ENOG4108R99 pseudouridine synthase HHJ27_RS08975 ENOG4108HMX isocitrate dehydrogenase (NADP) HHJ27_RS08980 ENOG4108RS6 transposase HHJ27_RS08990 ENOG41064WM Uncharacterized protein YcgX HHJ27_RS08995 ENOG4108XDN Transcriptional regulator HHJ27_RS09000 ENOG4105BZU Histidine kinase HHJ27_RS09005 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component HHJ27_RS09010 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB HHJ27_RS09020 ENOG410738I uncharacterized protein ymgC HHJ27_RS09025 ENOG4105BZU Histidine kinase HHJ27_RS09040 ENOG410658X HHJ27_RS09065 ENOG4108MGN ATP-binding component of a transport system HHJ27_RS09075 ENOG4107QMS site-determining protein HHJ27_RS09085 ENOG4105S66 prophage protein HHJ27_RS09090 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HHJ27_RS09100 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HHJ27_RS09110 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells HHJ27_RS09115 ENOG4105KT5 UmuD protein HHJ27_RS09120 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HHJ27_RS09125 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) HHJ27_RS09140 ENOG4105ED1 spovr family HHJ27_RS09150 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ27_RS09170 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HHJ27_RS09180 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HHJ27_RS09195 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HHJ27_RS09200 ENOG4108BSC Methyltransferase HHJ27_RS09205 ENOG4105E0A ABC, transporter HHJ27_RS09210 ENOG4105EHG Permease protein HHJ27_RS09215 ENOG4105S10 periplasmic binding protein HHJ27_RS09230 ENOG4105VDH Dihydroxyacetone kinase HHJ27_RS09235 ENOG4108UTZ Dihydroxyacetone kinase HHJ27_RS09240 ENOG4105CMT Dihydroxyacetone kinase HHJ27_RS09245 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HHJ27_RS09250 ENOG4105I1J Autotransporter HHJ27_RS09255 ENOG4105C3G gtp-binding protein HHJ27_RS09265 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HHJ27_RS09270 ENOG4105CHH sulfate transporter HHJ27_RS09275 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HHJ27_RS09290 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) HHJ27_RS09300 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HHJ27_RS09305 ENOG4108YY7 Invasion gene expression up-regulator SirB HHJ27_RS09310 ENOG41063JG Transcriptional regulator HHJ27_RS09320 ENOG4108RS6 transposase HHJ27_RS09335 ENOG4105EWV Sodium calcium exchanger membrane region HHJ27_RS09340 ENOG4105WS7 Cation transport regulator HHJ27_RS09345 ENOG4108NH8 Cation transport protein HHJ27_RS09350 ENOG41090EX DsrE family HHJ27_RS09355 ENOG4105ID0 Putative invasin HHJ27_RS09360 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ27_RS09365 ENOG4105BZU Histidine kinase HHJ27_RS09370 ENOG4105DQQ Major facilitator superfamily MFS_1 HHJ27_RS09375 ENOG4105CRU nitrate reductase, alpha subunit HHJ27_RS09380 ENOG4108IUE nitrate reductase beta subunit HHJ27_RS09385 ENOG4105R3A Nitrate reductase HHJ27_RS09390 ENOG41076YT nitrate reductase, gamma subunit HHJ27_RS09420 ENOG4105CIY formyltetrahydrofolate deformylase HHJ27_RS09430 ENOG4105D78 K07001 NTE family protein HHJ27_RS09435 ENOG4105I93 response regulator HHJ27_RS09440 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ27_RS09445 ENOG4108SAU DNA-binding protein H-ns HHJ27_RS09450 ENOG4107104 thymidine kinase HHJ27_RS09455 ENOG4105C0A alcohol dehydrogenase HHJ27_RS09460 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HHJ27_RS09465 ENOG4108J59 Extracellular solute-binding protein, family 5 HHJ27_RS09470 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ27_RS09475 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ27_RS09480 ENOG4105C3U ABC transporter HHJ27_RS09485 ENOG4108JQ7 (ABC) transporter HHJ27_RS09505 ENOG4107SVH Potassium channel protein HHJ27_RS09510 ENOG4105K9H YciI-like protein HHJ27_RS09515 ENOG410822N TonB family HHJ27_RS09520 ENOG4105NAU thioesterase Superfamily protein HHJ27_RS09530 ENOG4108S3I UPF0259 membrane protein HHJ27_RS09540 ENOG4105EIF outer membrane protein W HHJ27_RS09545 ENOG4108N8X transition metal ion binding HHJ27_RS09550 ENOG4108Z9Z response to DNA damage stimulus HHJ27_RS09560 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) HHJ27_RS09570 ENOG4105DK0 Indole-3-glycerol phosphate synthase HHJ27_RS09575 ENOG4108EFP Anthranilate synthase component II HHJ27_RS09580 ENOG4105CRQ synthase (Component I) HHJ27_RS09590 ENOG4105DB7 PHP domain protein HHJ27_RS09595 ENOG4107RTD sua5 ycio yrdc ywlc family protein HHJ27_RS09600 ENOG4105EG3 transmembrane signal peptide protein HHJ27_RS09605 ENOG4105FE9 pseudouridine synthase HHJ27_RS09620 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HHJ27_RS09625 ENOG4105UBK short-chain dehydrogenase reductase HHJ27_RS09630 ENOG4105ERU peptidase HHJ27_RS09635 ENOG4105RKX Protein of unknown function (DUF2498) HHJ27_RS09640 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ27_RS09645 ENOG4107R11 Transcriptional regulator HHJ27_RS09665 ENOG4107QM5 aconitate hydratase HHJ27_RS09675 ENOG4105EYK Phosphatidylglycerophosphatase B HHJ27_RS09680 ENOG4105Q4A inner membrane protein yciS HHJ27_RS09685 ENOG4105CFV Tetratricopeptide repeat protein HHJ27_RS09695 ENOG4108ZJT translation initiation factor, Sui1 HHJ27_RS09705 ENOG4105N2W Transcriptional regulator HHJ27_RS09710 ENOG410643D UPF0509 protein HHJ27_RS09715 ENOG4105BZU Histidine kinase HHJ27_RS09730 ENOG4105Q4T oxidoreductase HHJ27_RS09735 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HHJ27_RS09740 ENOG41067SE Tetr family transcriptional regulator HHJ27_RS09745 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ27_RS09750 ENOG4105BZS acriflavin resistance protein HHJ27_RS09755 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HHJ27_RS09760 ENOG4105C2C drug resistance transporter, Bcr CflA HHJ27_RS09765 ENOG4108JQ2 peptide transport system atp-binding protein HHJ27_RS09770 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HHJ27_RS09775 ENOG4108EU3 peptide transport system, permease HHJ27_RS09780 ENOG4108I5W peptide transport system, permease protein HHJ27_RS09785 ENOG4108HIY periplasmic HHJ27_RS09790 ENOG4105N0E Protein of unknown function (DUF2543) HHJ27_RS09795 ENOG4105CUB amino acid HHJ27_RS09805 ENOG4105CFQ glutamine synthetase HHJ27_RS09810 ENOG4108Z86 Glutamine amidotransferase HHJ27_RS09815 ENOG4107VRI Transcriptional regulator HHJ27_RS09820 ENOG4105C26 Dehydrogenase HHJ27_RS09825 ENOG4105CJP fad dependent oxidoreductase HHJ27_RS09830 ENOG4108JPW Aminotransferase HHJ27_RS09835 ENOG4105E51 psp operon transcriptional activator HHJ27_RS09840 ENOG41087YS Phage shock protein A HHJ27_RS09845 ENOG4105YYT phage shock protein B HHJ27_RS09850 ENOG4105FM1 phage shock protein C HHJ27_RS09855 ENOG4105NNG Peripheral inner membrane phage-shock protein HHJ27_RS09860 ENOG4105K8Z Phage shock protein HHJ27_RS09865 ENOG4105CM6 amino acid regulated cytosolic protein HHJ27_RS09875 ENOG4108JU8 Transcriptional regulator HHJ27_RS09880 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HHJ27_RS09885 ENOG4107S8C mandelate racemase muconate lactonizing HHJ27_RS09890 ENOG4105KXI murein peptide amidase A HHJ27_RS09910 ENOG4105EQ2 LysR family Transcriptional regulator HHJ27_RS09915 ENOG4107QSI ABC, transporter HHJ27_RS09920 ENOG4105D64 Mechanosensitive ion channel HHJ27_RS09925 ENOG4105S5I Membrane HHJ27_RS09930 ENOG4105Q9Y Universal stress protein HHJ27_RS09935 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HHJ27_RS09940 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ27_RS09945 ENOG4105CFC Transporter HHJ27_RS09950 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B HHJ27_RS09955 ENOG4105CH2 amidohydrolase HHJ27_RS09960 ENOG4106KR7 LysR family Transcriptional regulator HHJ27_RS09965 ENOG4105R1U AraC Family Transcriptional Regulator HHJ27_RS09980 ENOG4108DG9 Smr protein MutS2 HHJ27_RS09985 ENOG4105BZU Histidine kinase HHJ27_RS09995 ENOG4105C1J atp-dependent rna helicase HHJ27_RS10005 ENOG4107R08 Integrase HHJ27_RS10010 ENOG4107160 Rac prophage HHJ27_RS10015 ENOG41070YT Rac prophage HHJ27_RS10020 ENOG4106YAH restriction alleviation and modification enhancement HHJ27_RS10025 ENOG4108PNI recT protein HHJ27_RS10030 ENOG41076J9 exonuclease VIII HHJ27_RS10040 ENOG4107C82 Rac prophage HHJ27_RS10070 ENOG4105ZTP Protein of unknown function (DUF1376) HHJ27_RS10075 ENOG4105JBR DNA replication protein HHJ27_RS10095 ENOG4105WPN DNA integration recombination invertion protein HHJ27_RS10110 ENOG4105RWQ Protein of unknown function (DUF1364) HHJ27_RS10130 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HHJ27_RS10155 ENOG4106YSC HHJ27_RS10165 ENOG4105UZW Tail fiber assembly protein HHJ27_RS10190 ENOG4105IM0 capsid protein HHJ27_RS10265 ENOG4108X9F tail fiber protein HHJ27_RS10295 ENOG4105CC5 ABC transporter HHJ27_RS10300 ENOG4105CC5 ABC transporter HHJ27_RS10305 ENOG4105DIK (ABC) transporter HHJ27_RS10315 ENOG4108RW8 Universal stress protein F HHJ27_RS10320 ENOG4105FCK Membrane HHJ27_RS10325 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HHJ27_RS10330 ENOG4105IKK cytoplasmic protein HHJ27_RS10335 ENOG41090X5 Heat shock protein hslJ HHJ27_RS10340 ENOG4105C5I Dehydrogenase HHJ27_RS10345 ENOG4107H52 Dicarboxylate transport HHJ27_RS10350 ENOG410689M (LipO)protein HHJ27_RS10355 ENOG4105WXT Conserved Protein HHJ27_RS10360 ENOG4108WFR AraC Family Transcriptional Regulator HHJ27_RS10365 ENOG4105C26 Dehydrogenase HHJ27_RS10370 ENOG4105F11 amine oxidase HHJ27_RS10375 ENOG4105DXM phenylacetic acid degradation protein HHJ27_RS10380 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit HHJ27_RS10385 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit HHJ27_RS10390 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit HHJ27_RS10395 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit HHJ27_RS10400 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ27_RS10405 ENOG4105E39 Enoyl-CoA hydratase HHJ27_RS10410 ENOG4108UKI Enoyl-CoA hydratase HHJ27_RS10415 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HHJ27_RS10420 ENOG4108ZJI phenylacetic acid degradation protein HHJ27_RS10425 ENOG4105CHU acetyl-coa acetyltransferase HHJ27_RS10430 ENOG4105DZS Phenylacetate-CoA ligase HHJ27_RS10435 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein HHJ27_RS10440 ENOG4108Z0R Transferase HHJ27_RS10445 ENOG4107EF2 surface-exposed virulence protein HHJ27_RS10450 ENOG4107S5I aldo keto reductase HHJ27_RS10460 ENOG4105CQ7 ATP-dependent helicase HHJ27_RS10480 ENOG4107DB1 DUF218 domain HHJ27_RS10485 ENOG4105C26 Dehydrogenase HHJ27_RS10490 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ27_RS10495 ENOG4105CPW cytochrome b561 HHJ27_RS10500 ENOG4105UPP uncharacterized protein ydcA HHJ27_RS10505 ENOG4107NK6 Hok/gef family HHJ27_RS10515 ENOG4105C8Q Methyl-accepting chemotaxis HHJ27_RS10520 ENOG4105DDW LysR family Transcriptional regulator HHJ27_RS10525 ENOG4105E32 cytoplasmic protein HHJ27_RS10535 ENOG4105Z2P Protein of unknown function (DUF465) HHJ27_RS10540 ENOG4108RS6 transposase HHJ27_RS10555 ENOG4108Z9I -acetyltransferase HHJ27_RS10560 ENOG4107WE3 acetyltransferase YdcK HHJ27_RS10565 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HHJ27_RS10570 ENOG41088CC tellurite resistance protein tehB HHJ27_RS10575 ENOG4108KKZ (LipO)protein HHJ27_RS10580 ENOG4105DKK Benzoate HHJ27_RS10585 ENOG4108JCI Transcriptional regulator HHJ27_RS10590 ENOG4105CFP Peptidase U32 HHJ27_RS10595 ENOG4105RR0 Protein of unknown function (DUF2554) HHJ27_RS10605 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin HHJ27_RS10610 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HHJ27_RS10615 ENOG4107TYH extracellular solute-binding protein family 1 HHJ27_RS10620 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS10625 ENOG4105D81 ABC transporter, permease HHJ27_RS10630 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HHJ27_RS10650 ENOG410654E Membrane HHJ27_RS10655 ENOG4105R71 cytoplasmic protein HHJ27_RS10660 ENOG4108T9Y Inner membrane protein ydcZ HHJ27_RS10665 ENOG4108Z7F N-acetyltransferase HHJ27_RS10670 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein HHJ27_RS10675 ENOG4108WYP Transcriptional regulator HHJ27_RS10680 ENOG4105CHB tonB-dependent Receptor HHJ27_RS10685 ENOG4108NS2 receptor HHJ27_RS10690 ENOG4105C85 amino acid HHJ27_RS10695 ENOG4108N27 Glutathione S-transferase HHJ27_RS10705 ENOG4105CS6 Rhs element vgr protein HHJ27_RS10710 ENOG4105CNA YD repeat protein HHJ27_RS10730 ENOG4105EUZ Beta-lactamase domain protein HHJ27_RS10740 ENOG4108MEJ flavin reductase domain protein HHJ27_RS10745 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HHJ27_RS10750 ENOG4105JAB phenazine biosynthesis protein, phzf family HHJ27_RS10755 ENOG4105D0D Nitrate reductase 2, gamma subunit HHJ27_RS10760 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HHJ27_RS10765 ENOG4108IUE nitrate reductase beta subunit HHJ27_RS10770 ENOG4105CRU nitrate reductase, alpha subunit HHJ27_RS10775 ENOG4107QND Nitrite extrusion protein HHJ27_RS10785 ENOG4108UI3 Leucine Rich repeat HHJ27_RS10795 ENOG4105RPH Inner membrane protein YddG HHJ27_RS10805 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ27_RS10810 ENOG4108MG3 formate dehydrogenase HHJ27_RS10815 ENOG41084S7 Plasmid maintenance system antidote protein HHJ27_RS10825 ENOG4105DQ4 alcohol dehydrogenase HHJ27_RS10835 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HHJ27_RS10840 ENOG4105TPS biofilm-dependent modulation protein HHJ27_RS10845 ENOG4108Z9K Osmotically inducible protein HHJ27_RS10850 ENOG4107H6U ABC transporter HHJ27_RS10855 ENOG4105C3U ABC transporter HHJ27_RS10860 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ27_RS10865 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ27_RS10870 ENOG4105DEF Extracellular solute-binding protein, family 5 HHJ27_RS10875 ENOG4108UQS dipeptidase HHJ27_RS10880 ENOG4105BZU Histidine kinase HHJ27_RS10890 ENOG4105F32 YngK protein HHJ27_RS10895 ENOG4105E5D amino acid HHJ27_RS10900 ENOG4105CVK Glutamate decarboxylase HHJ27_RS10905 ENOG4107RAN Peptidase, M16 HHJ27_RS10910 ENOG4105PE1 Receptor HHJ27_RS10915 ENOG4105CQ0 ABC transporter HHJ27_RS10925 ENOG4105C4X radical SAM domain protein HHJ27_RS10930 ENOG4105ENH Sulfatase HHJ27_RS10935 ENOG4108NKV transcriptional regulator HHJ27_RS10945 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HHJ27_RS10950 ENOG4106PIH fimbrial-like protein ydeQ HHJ27_RS10955 ENOG4106318 fimbrial-like protein YdeR HHJ27_RS10960 ENOG4108WDE Fimbrial protein HHJ27_RS10965 ENOG4105CW0 outer membrane usher protein HHJ27_RS10975 ENOG4108RQP Major type 1 subunit fimbrin HHJ27_RS10995 ENOG4105CPC Aldo Keto reductase HHJ27_RS11000 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF HHJ27_RS11020 ENOG4105CV8 reductase HHJ27_RS11035 ENOG4105JQN Transcriptional regulator HHJ27_RS11040 ENOG4105CAF HipA N-terminal domain protein HHJ27_RS11045 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein HHJ27_RS11070 ENOG4105C2J ABC transporter HHJ27_RS11095 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound HHJ27_RS11100 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) HHJ27_RS11105 ENOG4105FFC UPF0187 protein HHJ27_RS11115 ENOG4105BZU Histidine kinase HHJ27_RS11120 ENOG4105M0C cytoplasmic protein HHJ27_RS11125 ENOG4105CSV Glutaminase HHJ27_RS11130 ENOG4105C26 Dehydrogenase HHJ27_RS11135 ENOG4105EGI Transcriptional regulator HHJ27_RS11155 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HHJ27_RS11160 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HHJ27_RS11165 ENOG4106DNR multiple antibiotic resistance protein HHJ27_RS11170 ENOG4105CS2 ec 3.2.1.21 HHJ27_RS11180 ENOG4105VCP PTS System HHJ27_RS11185 ENOG4105CK1 PTS System HHJ27_RS11195 ENOG4105FDP GntR family transcriptional regulator HHJ27_RS11200 ENOG4108594 Permease of the drug metabolite transporter HHJ27_RS11205 ENOG4105E5W Transporter HHJ27_RS11215 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria HHJ27_RS11220 ENOG4108YDI single-species biofilm formation on inanimate substrate HHJ27_RS11225 ENOG4105DGW oligopeptidase A HHJ27_RS11230 ENOG4105EMU Dehydrogenase HHJ27_RS11235 ENOG4107XBN GntR Family Transcriptional Regulator HHJ27_RS11240 ENOG41061EV selenium-binding protein YdfZ HHJ27_RS11245 ENOG4105DEI Mannitol dehydrogenase HHJ27_RS11255 ENOG4105CPQ Dehydrogenase HHJ27_RS11260 ENOG4105CXK mandelate racemase muconate lactonizing HHJ27_RS11275 ENOG4108MK9 spermidine N(1)-acetyltransferase HHJ27_RS11285 ENOG4105KBG Protein of unknown function (DUF1161) HHJ27_RS11290 ENOG4107QY8 reductase HHJ27_RS11295 ENOG4105C3J Cysteine desulfurase HHJ27_RS11300 ENOG4105QAX Iron-sulfur HHJ27_RS11305 ENOG4107KGK dmso reductase anchor subunit HHJ27_RS11310 ENOG4108NEM leader-binding protein dmsD HHJ27_RS11320 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ27_RS11325 ENOG4105DAG ROK family HHJ27_RS11330 ENOG4106NZI LysR family Transcriptional regulator HHJ27_RS11335 ENOG4105D94 Major Facilitator Superfamily HHJ27_RS11350 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HHJ27_RS11365 ENOG4105DSF transport protein HHJ27_RS11370 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ27_RS11375 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ27_RS11380 ENOG4105C5D exported protein HHJ27_RS11385 ENOG4105D5Q Arginine ornithine antiporter HHJ27_RS11390 ENOG410642E Short chain dehydrogenase HHJ27_RS11395 ENOG4105RA2 Membrane HHJ27_RS11400 ENOG4107EXC regulatoR HHJ27_RS11405 ENOG4105JJR Histidine kinase HHJ27_RS11415 ENOG4105C9Q fumarate hydratase class II HHJ27_RS11420 ENOG4107GFK fumarate HHJ27_RS11425 ENOG4105EIP mannose-6-phosphate isomerase HHJ27_RS11430 ENOG4106J39 exported protein HHJ27_RS11435 ENOG4108QNI outer membrane porin protein HHJ27_RS11440 ENOG4105CT4 transporter HHJ27_RS11445 ENOG4105CNT hydrolase family 2 HHJ27_RS11450 ENOG4105XEA Tetr family transcriptional regulator HHJ27_RS11455 ENOG4107ZQV short-chain dehydrogenase reductase HHJ27_RS11460 ENOG4107P2S Transcriptional regulator HHJ27_RS11465 ENOG4105CI1 PTS System HHJ27_RS11470 ENOG4105C87 Aminotransferase class I and II HHJ27_RS11480 ENOG4105D9R oxidoreductase HHJ27_RS11485 ENOG4106C6R beta-lactam resistance protein HHJ27_RS11490 ENOG4105QZ5 OriC-binding nucleoid-associated protein HHJ27_RS11495 ENOG4105M9B inner membrane protein ydgK HHJ27_RS11520 ENOG4108UQQ Electron transport complex HHJ27_RS11530 ENOG4105CSM endonuclease III HHJ27_RS11535 ENOG4105DUX Transporter HHJ27_RS11540 ENOG4108K3A Glutathione S-transferase HHJ27_RS11545 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HHJ27_RS11560 ENOG410642K Lysozyme inhibitor HHJ27_RS11570 ENOG4108XTF Outer Membrane Lipoprotein HHJ27_RS11585 ENOG4105Y49 secretion protein, HlyD family HHJ27_RS11590 ENOG4105DSW Fusaric acid resistance protein HHJ27_RS11595 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ27_RS11600 ENOG4107RGM aldo keto reductase HHJ27_RS11605 ENOG4105XZD Fe-S protein HHJ27_RS11610 ENOG4108WUH Transcriptional regulator, TetR family HHJ27_RS11615 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ27_RS11620 ENOG4108UYE Lactoylglutathione lyase HHJ27_RS11630 ENOG4107QRT dEAD DEAH box helicase HHJ27_RS11635 ENOG4105M2J Glutaredoxin HHJ27_RS11640 ENOG4105K4H Nlp p60 protein HHJ27_RS11645 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ27_RS11650 ENOG4105F27 Major Facilitator HHJ27_RS11665 ENOG4105F52 Transcriptional regulator HHJ27_RS11670 ENOG4105CZQ inner membrane transport protein YdhC HHJ27_RS11675 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HHJ27_RS11680 ENOG4108R6K riboflavin synthase, subunit alpha HHJ27_RS11705 ENOG4105N0V mono-oxygenase ydhR HHJ27_RS11710 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HHJ27_RS11715 ENOG4108Y7C Conserved Protein HHJ27_RS11720 ENOG4108NWD Cytochrome HHJ27_RS11725 ENOG4108393 oxidoreductase Fe-S subunit HHJ27_RS11730 ENOG4105JVW HHJ27_RS11735 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HHJ27_RS11740 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein HHJ27_RS11745 ENOG4105RFR Protein of unknown function (DUF2767) HHJ27_RS11750 ENOG4105CA9 Pyruvate kinase HHJ27_RS11755 ENOG4105KMX major outer membrane lipoprotein HHJ27_RS11760 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ27_RS11775 ENOG4105JRK feS assembly protein SufD HHJ27_RS11780 ENOG4105C3K feS assembly ATPase SufC HHJ27_RS11785 ENOG4105DIW FeS assembly protein SUFB HHJ27_RS11790 ENOG4108Z4V iron-sulfur cluster assembly HHJ27_RS11795 ENOG410671Z uncharacterized protein ydiH HHJ27_RS11800 ENOG4105KA0 thioesterase Superfamily protein HHJ27_RS11805 ENOG4105CQB FAD linked oxidase domain protein HHJ27_RS11810 ENOG4105IPI Membrane HHJ27_RS11825 ENOG4105SUA Ydil protein HHJ27_RS11830 ENOG4105EMV Major Facilitator HHJ27_RS11835 ENOG4105EMV Major Facilitator HHJ27_RS11850 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ27_RS11855 ENOG4105C1G acyl-Coa dehydrogenase HHJ27_RS11860 ENOG4105W4W Transcriptional regulator HHJ27_RS11865 ENOG4105CV7 Electron transfer flavoprotein HHJ27_RS11870 ENOG4105C10 Electron transfer flavoprotein HHJ27_RS11875 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ27_RS11880 ENOG41090P5 ferredoxin-like protein HHJ27_RS11885 ENOG4105CEY Amp-dependent synthetase and ligase HHJ27_RS11890 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HHJ27_RS11900 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ27_RS11915 ENOG4108TC0 Diguanylate phosphodiesterase HHJ27_RS11920 ENOG4108QBX (LipO)protein HHJ27_RS11930 ENOG4108V06 Glutathione peroxidase HHJ27_RS11965 ENOG41082NX 50s ribosomal protein l35 HHJ27_RS11970 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HHJ27_RS11990 ENOG4108NE3 Salt-induced outer membrane protein HHJ27_RS11995 ENOG4105DE4 1-phosphofructokinase HHJ27_RS12000 ENOG4105P10 Uncharacterized protein ydiZ HHJ27_RS12010 ENOG4107PN8 YfeABCD locus regulator HHJ27_RS12015 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HHJ27_RS12020 ENOG4107K5X Membrane-bound metal-dependent hydrolase HHJ27_RS12025 ENOG4108ETY sodium dicarboxylate symporter HHJ27_RS12040 ENOG4105CH6 catalase HHJ27_RS12050 ENOG4105F8D glycoside hydrolase family 4 HHJ27_RS12055 ENOG4105EZV Transcriptional regulator HHJ27_RS12060 ENOG4105VCP PTS System HHJ27_RS12065 ENOG4105CK1 PTS System HHJ27_RS12070 ENOG4105VZJ PTS System HHJ27_RS12075 ENOG4105KKI DNA-binding transcriptional activator OsmE HHJ27_RS12085 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HHJ27_RS12095 ENOG4108SPG Periplasmic Protein HHJ27_RS12105 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) HHJ27_RS12125 ENOG4105CGK Exodeoxyribonuclease III HHJ27_RS12130 ENOG4108RSN SNARE associated Golgi HHJ27_RS12135 ENOG4108KCW iron-sulfur cluster binding HHJ27_RS12140 ENOG4108N5C SNARE associated Golgi protein-related protein HHJ27_RS12145 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HHJ27_RS12150 ENOG4105VNH ABC transporter solute-binding protein HHJ27_RS12155 ENOG4105CXZ ABC transporter, permease HHJ27_RS12160 ENOG4108VGW abc transporter atp-binding protein HHJ27_RS12165 ENOG4107RM6 sulfurtransferase HHJ27_RS12170 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HHJ27_RS12175 ENOG4105M6F mutator MutT protein HHJ27_RS12180 ENOG4105MTM Protein of unknown function (DUF1496) HHJ27_RS12185 ENOG4105D82 Glutamate dehydrogenase HHJ27_RS12195 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ27_RS12205 ENOG41069NU Nitroreductase HHJ27_RS12210 ENOG4105D07 Signal peptide peptidase, SppA HHJ27_RS12215 ENOG4105HDK L-asparaginase HHJ27_RS12220 ENOG4108RWI nicotinamidase HHJ27_RS12225 ENOG4108KUU Inner membrane metabolite transport protein ydjE HHJ27_RS12230 ENOG4105E98 transcriptional regulator DeoR family HHJ27_RS12235 ENOG4105CPC Aldo Keto reductase HHJ27_RS12240 ENOG4107UH8 sugar kinase HHJ27_RS12245 ENOG4105D2N Aldolase HHJ27_RS12250 ENOG4105CPQ Dehydrogenase HHJ27_RS12255 ENOG4107TE1 transport protein HHJ27_RS12260 ENOG4105CPQ Dehydrogenase HHJ27_RS12265 ENOG4105VUT cytoplasmic protein HHJ27_RS12275 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ27_RS12280 ENOG4105DSB aldose 1-epimerase HHJ27_RS12285 ENOG4105CV8 reductase HHJ27_RS12290 ENOG4105GNX MltA-interacting MipA family protein HHJ27_RS12295 ENOG4105CYN Serine protein kinase HHJ27_RS12305 ENOG4106KTS Inner membrane protein yeaI HHJ27_RS12310 ENOG4108KHP Diguanylate cyclase HHJ27_RS12315 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HHJ27_RS12330 ENOG4105R1U AraC Family Transcriptional Regulator HHJ27_RS12335 ENOG4105DJ2 Major Facilitator Superfamily HHJ27_RS12340 ENOG4105K78 MarR family Transcriptional regulator HHJ27_RS12345 ENOG4105UCG Domain of unknown function (DUF333) HHJ27_RS12350 ENOG410620I Diguanylate cyclase HHJ27_RS12355 ENOG4106G4W HHJ27_RS12365 ENOG4105Y3U Transglycosylase-associated protein HHJ27_RS12370 ENOG4105YP6 Domain of unknown function (DUF1869) HHJ27_RS12375 ENOG4108YS1 cytoplasmic protein HHJ27_RS12385 ENOG4105EJC lysr family transcriptional regulator HHJ27_RS12390 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HHJ27_RS12395 ENOG4105C94 Transporter HHJ27_RS12400 ENOG4105DVW rieske (2Fe-2S) HHJ27_RS12405 ENOG4105E3J oxidoreductase HHJ27_RS12410 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HHJ27_RS12415 ENOG4105CEY Amp-dependent synthetase and ligase HHJ27_RS12420 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ27_RS12425 ENOG41072GX Peptidase M22 Glycoprotease HHJ27_RS12430 ENOG4105DVT helicase HHJ27_RS12435 ENOG4105M4H endoribonuclease L-psp HHJ27_RS12440 ENOG4105V2F Uncharacterized protein yoac HHJ27_RS12450 ENOG4105CRQ synthase (Component I) HHJ27_RS12460 ENOG4105EJQ L-serine dehydratase HHJ27_RS12465 ENOG4107XTP (EAL) domain protein HHJ27_RS12470 ENOG4105EE5 Membrane protein terC HHJ27_RS12475 ENOG4105DAS pts system HHJ27_RS12480 ENOG4105ETZ PTS System HHJ27_RS12485 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ27_RS12500 ENOG4105DHI Methyltransferase HHJ27_RS12515 ENOG4105Q3Y exported protein HHJ27_RS12525 ENOG4105TIK HHJ27_RS12530 ENOG4105J4Q Transcriptional regulator HHJ27_RS12535 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ27_RS12545 ENOG4105CN1 protease HHJ27_RS12550 ENOG41073DY may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity) HHJ27_RS12555 ENOG4108ZGC gaf domain protein HHJ27_RS12560 ENOG4105H2K paraquat-inducible protein a HHJ27_RS12565 ENOG4105DY2 Paraquat-inducible protein b HHJ27_RS12575 ENOG4105WT8 Protein of unknown function (DUF1480) HHJ27_RS12580 ENOG4105UVW uncharacterized protein yebW HHJ27_RS12585 ENOG4108R1E Serine threonine protein phosphatase 1 HHJ27_RS12590 ENOG4105NKT exported protein HHJ27_RS12595 ENOG4108PNC copper resistance HHJ27_RS12600 ENOG4105FXM Copper resistance protein HHJ27_RS12605 ENOG4105MPK DNA polymerase III subunit theta HHJ27_RS12610 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ27_RS12615 ENOG4105UMD exodeoxyribonuclease X HHJ27_RS12620 ENOG4105CUG Oligopeptidase b HHJ27_RS12635 ENOG4108Q2J Inner membrane protein YebE HHJ27_RS12645 ENOG4105X2V dna damage-inducible protein HHJ27_RS12655 ENOG4108UHU Aldolase HHJ27_RS12660 ENOG4105C01 Dihydroxy-acid dehydratase HHJ27_RS12665 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HHJ27_RS12670 ENOG4106KNT transcriptional regulator HHJ27_RS12675 ENOG4105CA9 Pyruvate kinase HHJ27_RS12680 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HHJ27_RS12685 ENOG4108RS6 transposase HHJ27_RS12690 ENOG4105DR5 peptidase HHJ27_RS12695 ENOG4105NXV High-affinity zinc uptake system protein HHJ27_RS12705 ENOG4105FAV ABC, transporter HHJ27_RS12725 ENOG4107S01 Repressor protein MetJ HHJ27_RS12735 ENOG4105CDY transcriptional regulatory protein HHJ27_RS12740 ENOG4108TIT dATP pyrophosphohydrolase HHJ27_RS12750 ENOG4105D3W isochorismatase HHJ27_RS12755 ENOG41081XQ Conserved Protein HHJ27_RS12760 ENOG4105WJG Glutathione HHJ27_RS12775 ENOG4107QY8 reductase HHJ27_RS12780 ENOG4105CUW cytochrome C-TYPE protein HHJ27_RS12790 ENOG4106ZCM YecM protein HHJ27_RS12800 ENOG4105W13 flagellar protein HHJ27_RS12805 ENOG4105D7B Flagellar biosynthesis protein flha HHJ27_RS12810 ENOG4105D00 flagellar biosynthetic protein flhB HHJ27_RS12815 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HHJ27_RS12820 ENOG4108VYJ response regulator receiver protein HHJ27_RS12830 ENOG4105BZU Histidine kinase HHJ27_RS12835 ENOG4105C8Q Methyl-accepting chemotaxis HHJ27_RS12840 ENOG4105C8Q Methyl-accepting chemotaxis HHJ27_RS12845 ENOG4108V3W Chemotaxis protein, CheW HHJ27_RS12850 ENOG4105CBS Chea signal transduction histidine kinase HHJ27_RS12855 ENOG4105ER2 Ompa motb domain protein HHJ27_RS12860 ENOG4107RD7 Flagellar Motor Protein, MotA HHJ27_RS12865 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HHJ27_RS12875 ENOG4108VA4 Universal stress protein HHJ27_RS12885 ENOG4108K4C ec 3.1.3.12 HHJ27_RS12890 ENOG4105CNN ABC, transporter HHJ27_RS12895 ENOG4105C2J ABC transporter HHJ27_RS12900 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HHJ27_RS12905 ENOG4108UEC Ferritin-like protein HHJ27_RS12910 ENOG4105N4N Protein of unknown function (DUF2766) HHJ27_RS12920 ENOG4105P23 (LipO)protein HHJ27_RS12925 ENOG41090A1 ferritin HHJ27_RS12930 ENOG4105VVZ metal-binding protein HHJ27_RS12935 ENOG4105E0U tyrosine-specific transport protein HHJ27_RS12940 ENOG4106RHG Yeca family HHJ27_RS12950 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) HHJ27_RS12990 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ27_RS13000 ENOG4105XVG cytoplasmic protein HHJ27_RS13005 ENOG4105VJY transcriptional regulator HHJ27_RS13010 ENOG4105CDA abc transporter atp-binding protein HHJ27_RS13015 ENOG4105E5Q amino acid AbC transporter HHJ27_RS13020 ENOG4105K6H D-cysteine desulfhydrase HHJ27_RS13025 ENOG4105EAB amino acid AbC transporter HHJ27_RS13030 ENOG4108M9K flagella biosynthesis protein FliZ HHJ27_RS13035 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ27_RS13040 ENOG4105I03 Flagellin HHJ27_RS13045 ENOG4105DTS flagellar hook-associated HHJ27_RS13050 ENOG4105MQ3 flagellar protein FliS HHJ27_RS13055 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) HHJ27_RS13060 ENOG4105E5K Alpha-amylase HHJ27_RS13065 ENOG4108W9D (LipO)protein HHJ27_RS13070 ENOG41066VF YeeE YedE family protein HHJ27_RS13080 ENOG4108RAV Conserved protein HHJ27_RS13085 ENOG4108HF7 Gcn5-related n-acetyltransferase HHJ27_RS13100 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HHJ27_RS13105 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ27_RS13110 ENOG41090PJ Flagellar assembly protein HHJ27_RS13115 ENOG4108JIR Flagellum-specific ATP synthase HHJ27_RS13120 ENOG4105GSA Flagellar export protein flij HHJ27_RS13125 ENOG4105WF4 Flagellar hook-length control protein HHJ27_RS13130 ENOG4107ZI8 flagellar basal body-associated protein flil HHJ27_RS13135 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ27_RS13140 ENOG4105DD5 Flagellar motor switch protein HHJ27_RS13145 ENOG4105K0P flagellar biosynthesis protein HHJ27_RS13150 ENOG4105CN7 Flagellar biosynthetic protein FliP HHJ27_RS13160 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HHJ27_RS13165 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HHJ27_RS13175 ENOG4105YX3 cellular response to acidity HHJ27_RS13190 ENOG4105VNZ cytoplasmic protein HHJ27_RS13195 ENOG4105CKW Inner membrane protein yedI HHJ27_RS13200 ENOG4105FDR Membrane HHJ27_RS13205 ENOG41090BB DNA mismatch endonuclease (vsr) HHJ27_RS13210 ENOG4105DVF Cytosine-specific methyltransferase HHJ27_RS13215 ENOG4105EST Metal Dependent Phosphohydrolase HHJ27_RS13220 ENOG4105Y0K Inner membrane protein YedR HHJ27_RS13225 ENOG4105ZIT Porin Gram-negative type HHJ27_RS13235 ENOG4107ZY3 Histidine kinase HHJ27_RS13240 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ27_RS13245 ENOG4105VT2 5-hydroxyisourate hydrolase HHJ27_RS13260 ENOG4108MEK Metal-binding protein YodA HHJ27_RS13270 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) HHJ27_RS13290 ENOG4105EYM Major Facilitator superfamily HHJ27_RS13295 ENOG4105BZ1 (ABC) transporter HHJ27_RS13310 ENOG4105C0W non-ribosomal peptide synthetase HHJ27_RS13330 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HHJ27_RS13335 ENOG4107ZSV Receptor HHJ27_RS13340 ENOG4105TNG K13735 adhesin invasin HHJ27_RS13355 ENOG4105CSH Transporter HHJ27_RS13360 ENOG4105FYV Amp nucleosidase HHJ27_RS13365 ENOG4105CDY transcriptional regulatory protein HHJ27_RS13375 ENOG4105UQX Mate efflux family protein HHJ27_RS13405 ENOG4106P55 Transcriptional regulator HHJ27_RS13415 ENOG4108PXI ErfK YbiS YcfS YnhG HHJ27_RS13430 ENOG4108YZT Adenosylcobinamide kinase HHJ27_RS13440 ENOG4105GTN ParB Domain Protein Nuclease HHJ27_RS13445 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HHJ27_RS13475 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ27_RS13480 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ27_RS13485 ENOG4105JXH GntR family transcriptional regulator HHJ27_RS13490 ENOG4108MRH transcriptional regulatory protein HHJ27_RS13495 ENOG4105HDK L-asparaginase HHJ27_RS13500 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ27_RS13510 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) HHJ27_RS13515 ENOG4105CEE C4-dicarboxylate transporter HHJ27_RS13530 ENOG4105D44 asparaginase HHJ27_RS13560 ENOG4105ETE Transcriptional regulator (LacI family HHJ27_RS13590 ENOG4105EMF GntR family transcriptional regulator HHJ27_RS13595 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HHJ27_RS13600 ENOG4108RTU Aldolase HHJ27_RS13610 ENOG4105DJB Major Facilitator Superfamily HHJ27_RS13620 ENOG4107YNJ LysR family Transcriptional regulator HHJ27_RS13630 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ27_RS13650 ENOG4108RVA ribokinase HHJ27_RS13665 ENOG41080QX K07048 phosphotriesterase-related protein HHJ27_RS13735 ENOG4108F5E vimentin HHJ27_RS13740 ENOG4108YIV HHJ27_RS13760 ENOG4106H6R UPF0380 protein HHJ27_RS13765 ENOG4105MFG Antirestriction protein HHJ27_RS13770 ENOG4108YGG dna repair protein HHJ27_RS13780 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ27_RS13815 ENOG4105DR8 Membrane HHJ27_RS13825 ENOG4105DZ1 carboxypeptidase HHJ27_RS13830 ENOG4105CJB Exodeoxyribonuclease I HHJ27_RS13840 ENOG4105CUC YeeE YedE family protein HHJ27_RS13845 ENOG4105CUB amino acid HHJ27_RS13855 ENOG4105EQ1 Transcriptional regulator HHJ27_RS13860 ENOG4107SRH Nad-dependent epimerase dehydratase HHJ27_RS13865 ENOG4105KRQ Addiction module toxin, Txe YoeB family HHJ27_RS13870 ENOG4105VTW prevent-host-death family HHJ27_RS13885 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) HHJ27_RS13895 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HHJ27_RS13900 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HHJ27_RS13920 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HHJ27_RS13925 ENOG4105C6Y Udp-glucose 6-dehydrogenase HHJ27_RS13930 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HHJ27_RS13935 ENOG4108MKI Glycosyl transferase, family 2 HHJ27_RS13965 ENOG4105D5D udp-galactopyranose mutase HHJ27_RS13970 ENOG4105ER6 polysaccharide biosynthesis protein HHJ27_RS13975 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase HHJ27_RS13980 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HHJ27_RS13985 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase HHJ27_RS13990 ENOG4105C1B dTDP-glucose 4-6-dehydratase HHJ27_RS13995 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ27_RS14000 ENOG4105G1A colanic acid biosynthesis protein HHJ27_RS14005 ENOG4107T8Q Glycosyl transferase (Group 1 HHJ27_RS14010 ENOG4105C74 pyruvyl transferase HHJ27_RS14015 ENOG4105PSV Polysaccharide Biosynthesis Protein HHJ27_RS14020 ENOG4105D3Q Sugar transferase HHJ27_RS14025 ENOG4107QKV phosphomannomutase HHJ27_RS14030 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HHJ27_RS14035 ENOG4106CD9 glycosyl transferase group 1 HHJ27_RS14040 ENOG4105FGF GDP-mannose mannosyl hydrolase HHJ27_RS14045 ENOG4105C30 Nad-dependent epimerase dehydratase HHJ27_RS14050 ENOG4105C0K Gdp-mannose 4,6-dehydratase HHJ27_RS14055 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HHJ27_RS14060 ENOG4105ECJ Glycosyl Transferase HHJ27_RS14065 ENOG4108NYJ Colanic acid HHJ27_RS14070 ENOG4107RXY Glycosyl transferase HHJ27_RS14075 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HHJ27_RS14080 ENOG41090RK glycosyl transferase HHJ27_RS14085 ENOG4105D75 Capsular exopolysaccharide family HHJ27_RS14090 ENOG4105KJF protein tyrosine phosphatase HHJ27_RS14095 ENOG4105DAY polysaccharide export protein HHJ27_RS14105 ENOG4105EE5 Membrane protein terC HHJ27_RS14110 ENOG4105EQR Transposase IS116 IS110 IS902 HHJ27_RS14125 ENOG4108GAE asmA family HHJ27_RS14135 ENOG4105DBI uridine monophosphokinase HHJ27_RS14140 ENOG4105BZU Histidine kinase HHJ27_RS14145 ENOG4105D03 DNA-3-methyladenine glycosylase II HHJ27_RS14150 ENOG4105R8A Heat shock protein HHJ27_RS14155 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding HHJ27_RS14160 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HHJ27_RS14165 ENOG4108M24 von Willebrand factor, type A HHJ27_RS14200 ENOG4105EB3 Histidine kinase HHJ27_RS14205 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ27_RS14210 ENOG4105KWI UPF0339 protein HHJ27_RS14215 ENOG4105X54 addiction module antidote protein HHJ27_RS14225 ENOG4105CFP Peptidase U32 HHJ27_RS14230 ENOG41076Z6 Uncharacterized protein yegR HHJ27_RS14245 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HHJ27_RS14250 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ27_RS14255 ENOG41090UW PTS System HHJ27_RS14260 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HHJ27_RS14275 ENOG4105EIE fructose-bisphosphate aldolase HHJ27_RS14280 ENOG4105EAA nucleoside HHJ27_RS14285 ENOG4108KD5 ADP-ribosylation crystallin J1 HHJ27_RS14290 ENOG4108TFM Kinase, PfkB family HHJ27_RS14295 ENOG4105FDP GntR family transcriptional regulator HHJ27_RS14300 ENOG4108UQ1 hydrolase, family 25 HHJ27_RS14305 ENOG4105DWF phosphomethylpyrimidine kinase HHJ27_RS14320 ENOG41061MD high-affinity nickel-transporter HHJ27_RS14325 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HHJ27_RS14330 ENOG410662B Type-1 fimbrial protein HHJ27_RS14335 ENOG4105CW0 outer membrane usher protein HHJ27_RS14340 ENOG4108MQF Chaperone HHJ27_RS14345 ENOG41063W2 Fimbrial protein HHJ27_RS14350 ENOG41067AK Protein of unknown function (DUF2574) HHJ27_RS14355 ENOG4105D1F ATP-binding protein HHJ27_RS14365 ENOG4108KDT Molybdate metabolism regulator HHJ27_RS14370 ENOG4108KDT Molybdate metabolism regulator HHJ27_RS14375 ENOG4108KDT Molybdate metabolism regulator HHJ27_RS14395 ENOG4105DEG Vwa containing coxe family protein HHJ27_RS14400 ENOG410903U zinc ion binding HHJ27_RS14405 ENOG4108YCW (LipO)protein HHJ27_RS14410 ENOG4108W15 Protein of unknown function (DUF1456) HHJ27_RS14415 ENOG4108NEV two component transcriptional regulator, LytTR family HHJ27_RS14420 ENOG4108HRK Histidine kinase HHJ27_RS14425 ENOG4108XDN Transcriptional regulator HHJ27_RS14435 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HHJ27_RS14440 ENOG4108IJ8 ABC transporter HHJ27_RS14445 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HHJ27_RS14450 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HHJ27_RS14455 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HHJ27_RS14460 ENOG4105CXG d-lactate dehydrogenase HHJ27_RS14465 ENOG41061WM D-Alanyl-D-Alanine HHJ27_RS14470 ENOG41069YE inner membrane protein yohC HHJ27_RS14475 ENOG4105KHU inner membrane protein YohD HHJ27_RS14480 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HHJ27_RS14485 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ27_RS14495 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HHJ27_RS14505 ENOG41067MG lrgb family HHJ27_RS14515 ENOG4107GZ4 SanA protein HHJ27_RS14520 ENOG4105Y9N Membrane HHJ27_RS14525 ENOG4105BZ8 glutamate synthase HHJ27_RS14530 ENOG4107SJI Dehydrogenase HHJ27_RS14535 ENOG4108HWV )-transporter HHJ27_RS14540 ENOG4105C2J ABC transporter HHJ27_RS14545 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HHJ27_RS14550 ENOG41060NJ transcriptional regulator HHJ27_RS14555 ENOG4105DHF Membrane HHJ27_RS14570 ENOG4105D05 Receptor HHJ27_RS14575 ENOG4108IQI permease HHJ27_RS14580 ENOG4105DUM transcriptional regulator, lysR family HHJ27_RS14585 ENOG4105HMI Membrane HHJ27_RS14595 ENOG4105DD7 kinase (PfkB family HHJ27_RS14600 ENOG4105D9N nucleoside HHJ27_RS14610 ENOG4108Y4K DNA-binding transcriptional activator HHJ27_RS14615 ENOG4105D9N nucleoside HHJ27_RS14620 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HHJ27_RS14625 ENOG4105DD7 kinase (PfkB family HHJ27_RS14630 ENOG4105DM4 PTS System HHJ27_RS14635 ENOG4105DE4 1-phosphofructokinase HHJ27_RS14640 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HHJ27_RS14645 ENOG4105S8Q sugar efflux transporter HHJ27_RS14650 ENOG4105KRS Proteinase inhibitor HHJ27_RS14660 ENOG4105DEI Mannitol dehydrogenase HHJ27_RS14665 ENOG4105CKI cobalamin synthesis protein HHJ27_RS14670 ENOG41076MN Phosphoesterase, PA-phosphatase related HHJ27_RS14675 ENOG4107TT5 NLP P60 protein HHJ27_RS14680 ENOG4105CXC rtn protein HHJ27_RS14685 ENOG4105E43 Extracellular solute-binding protein, family 5 HHJ27_RS14690 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HHJ27_RS14695 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HHJ27_RS14700 ENOG4108JQ5 ABC transporter HHJ27_RS14705 ENOG4105HG6 HHJ27_RS14710 ENOG4105C2C drug resistance transporter, Bcr CflA HHJ27_RS14715 ENOG4105I08 Pseudouridine synthase HHJ27_RS14720 ENOG4105CFI type iii restriction protein res subunit HHJ27_RS14740 ENOG4105E68 Sulfatase HHJ27_RS14750 ENOG4108MGN ATP-binding component of a transport system HHJ27_RS14755 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ27_RS14760 ENOG4105KWW Biogenesis protein HHJ27_RS14765 ENOG4107QX9 Thiol disulfide interChange protein HHJ27_RS14770 ENOG4105DA4 cytochrome c-type biogenesis protein HHJ27_RS14780 ENOG4105X3C heme exporter protein HHJ27_RS14785 ENOG41060IM Heme exporter protein HHJ27_RS14790 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HHJ27_RS14795 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS14800 ENOG4105CUW cytochrome C-TYPE protein HHJ27_RS14805 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HHJ27_RS14810 ENOG4105GXZ Ferredoxin-type protein NapH HHJ27_RS14815 ENOG4108BGM Quinol dehydrogenase periplasmic component HHJ27_RS14825 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HHJ27_RS14830 ENOG4108ZNS ferredoxin-type protein NapF HHJ27_RS14845 ENOG4105IBP Cyclic peptide transporter HHJ27_RS14850 ENOG4105CF1 Alkylated DNA repair protein HHJ27_RS14855 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ27_RS14860 ENOG4105CJ2 (LipO)protein HHJ27_RS14865 ENOG4105FCK Membrane HHJ27_RS14870 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HHJ27_RS14875 ENOG41068CG regulatoR HHJ27_RS14880 ENOG4105BZU Histidine kinase HHJ27_RS14885 ENOG4105BZU Histidine kinase HHJ27_RS14890 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ27_RS14895 ENOG4107QP7 CoA-transferase subunit A HHJ27_RS14900 ENOG4107QNJ CoA-transferase subunit B HHJ27_RS14905 ENOG4105CRW Short chain fatty acid transporter HHJ27_RS14910 ENOG4105CHU acetyl-coa acetyltransferase HHJ27_RS14915 ENOG4105EDV vault protein HHJ27_RS14920 ENOG41081SK signal peptide protein HHJ27_RS14925 ENOG4107S52 alpha-2-macroglobulin domain protein HHJ27_RS14930 ENOG4108QJJ Protein of unknown function (DUF1175) HHJ27_RS14935 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HHJ27_RS14940 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ27_RS14950 ENOG4107GHC outer membrane autotransporter HHJ27_RS14955 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ27_RS14960 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ27_RS14965 ENOG4105XPH Ferredoxin HHJ27_RS14970 ENOG4105FQR PH-inducible protein involved in stress response HHJ27_RS14975 ENOG4105CZM Major Facilitator HHJ27_RS14990 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HHJ27_RS14995 ENOG4105CXY transporter HHJ27_RS15000 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HHJ27_RS15010 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ27_RS15015 ENOG4105DNE Transposase HHJ27_RS15035 ENOG4107258 Transcriptional regulator HHJ27_RS15040 ENOG4108EWA cinA-like protein HHJ27_RS15045 ENOG4108UII YfaZ family HHJ27_RS15095 ENOG4106GZG polymyxin resistance protein B HHJ27_RS15100 ENOG4105CEY Amp-dependent synthetase and ligase HHJ27_RS15110 ENOG4108IPT Naphthoate synthase HHJ27_RS15125 ENOG4105E4F Isochorismate synthase HHJ27_RS15130 ENOG4105TNS Conserved Protein HHJ27_RS15135 ENOG4107YB6 acetyltransferase, (GNAT) family HHJ27_RS15145 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is HHJ27_RS15150 ENOG4107VAM peptidase, m28 HHJ27_RS15155 ENOG4105GDX Domain of unknown function (DUF1877) HHJ27_RS15165 ENOG4105C8S subunit m HHJ27_RS15170 ENOG4105D65 subunit l HHJ27_RS15180 ENOG4107UFS subunit j HHJ27_RS15195 ENOG4108IEH NADH dehydrogenase subunit g HHJ27_RS15200 ENOG4107QIZ NADH dehydrogenase HHJ27_RS15205 ENOG4105GKE subunit e HHJ27_RS15225 ENOG4107NQ8 LysR family Transcriptional regulator HHJ27_RS15230 ENOG4105CHM Aminotransferase HHJ27_RS15240 ENOG4107QWE )-transporter HHJ27_RS15245 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HHJ27_RS15250 ENOG4105XWI UPF0304 protein HHJ27_RS15260 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HHJ27_RS15265 ENOG4105C6K Malic enzyme HHJ27_RS15270 ENOG4105CSX c4-dicarboxylate anaerobic carrier HHJ27_RS15275 ENOG4105PTV Nudix Hydrolase HHJ27_RS15280 ENOG4108RE9 Phosphodiesterase HHJ27_RS15285 ENOG4108SHQ Glutathione S-transferase HHJ27_RS15290 ENOG4105CYM Glutathione S-transferase HHJ27_RS15295 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HHJ27_RS15300 ENOG4105ECP epimerase HHJ27_RS15305 ENOG4105DNE Transposase HHJ27_RS15310 ENOG4108JEH abc transporter atp-binding protein HHJ27_RS15315 ENOG4106YG3 ABC transporter HHJ27_RS15320 ENOG4105DSP amino acid AbC transporter HHJ27_RS15325 ENOG4105E89 ABC transporter HHJ27_RS15330 ENOG4105E89 ABC transporter HHJ27_RS15335 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HHJ27_RS15340 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HHJ27_RS15345 ENOG4105E96 Colicin v production protein HHJ27_RS15350 ENOG4108S3P Sporulation domain protein HHJ27_RS15355 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HHJ27_RS15365 ENOG4105DQR SNARE associated Golgi HHJ27_RS15375 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ27_RS15385 ENOG4106WZ1 flagella biosynthesis regulator HHJ27_RS15390 ENOG4105F9N Major Facilitator Superfamily HHJ27_RS15395 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ27_RS15400 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) HHJ27_RS15405 ENOG4105MH2 YfcL protein HHJ27_RS15410 ENOG4108BPE -transporting atpase HHJ27_RS15415 ENOG4105EJ9 Membrane HHJ27_RS15425 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase HHJ27_RS15430 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) HHJ27_RS15445 ENOG4105US4 fimbrial-like protein yfcP HHJ27_RS15450 ENOG4105UGQ Fimbrial HHJ27_RS15455 ENOG4105NEV Fimbrial HHJ27_RS15460 ENOG4108FZ9 Chaperone HHJ27_RS15465 ENOG4106PG1 outer membrane usher protein HHJ27_RS15475 ENOG4108BY2 phosphohistidine phosphatase HHJ27_RS15490 ENOG4105KZW UPF0381 protein HHJ27_RS15495 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HHJ27_RS15505 ENOG410903C (LipO)protein HHJ27_RS15510 ENOG4105S64 Formate nitrite transporter HHJ27_RS15525 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HHJ27_RS15530 ENOG4105D7K pfkb domain protein HHJ27_RS15535 ENOG4108HKT sucrose-6-phosphate hydrolase HHJ27_RS15540 ENOG4106NDP Transcriptional regulator HHJ27_RS15555 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ27_RS15560 ENOG4105CW7 secretion protein, HlyD family HHJ27_RS15565 ENOG4108WQH regulatoR HHJ27_RS15570 ENOG4105BZU Histidine kinase HHJ27_RS15575 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HHJ27_RS15580 ENOG4108N2Y auxin Efflux HHJ27_RS15585 ENOG4105CFN oxalyl-CoA decarboxylase HHJ27_RS15595 ENOG4108V08 YfdX protein HHJ27_RS15605 ENOG4105W9M Membrane HHJ27_RS15610 ENOG4105D1S lipid A biosynthesis HHJ27_RS15620 ENOG4105CHM Aminotransferase HHJ27_RS15625 ENOG4108HRK Histidine kinase HHJ27_RS15630 ENOG4105DY9 regulatoR HHJ27_RS15635 ENOG4108CIP transcriptional regulator HHJ27_RS15640 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ27_RS15645 ENOG4105CN9 Peptidase m42 family protein HHJ27_RS15650 ENOG4105DC7 peptidase M24 HHJ27_RS15655 ENOG410863U PTS System HHJ27_RS15660 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ27_RS15675 ENOG4109076 Conserved Protein HHJ27_RS15685 ENOG4105D9N nucleoside HHJ27_RS15690 ENOG4108KMM Diguanylate cyclase HHJ27_RS15705 ENOG4105HZG regulatoR HHJ27_RS15710 ENOG4105GXM Putative transcription regulator (DUF1323) HHJ27_RS15740 ENOG4105CN8 Transcriptional regulator HHJ27_RS15750 ENOG4105EAA nucleoside HHJ27_RS15755 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HHJ27_RS15760 ENOG4108NFH Sugar hydrolase HHJ27_RS15765 ENOG4108M0I Transcriptional regulator HHJ27_RS15770 ENOG4105DHU Bile acid HHJ27_RS15775 ENOG4105VRT cytoplasmic protein HHJ27_RS15795 ENOG4105C6T cysteine synthase HHJ27_RS15805 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ27_RS15810 ENOG4105C5Y PTS System HHJ27_RS15820 ENOG4105M0Y HHJ27_RS15825 ENOG4105C6T cysteine synthase HHJ27_RS15830 ENOG4108IJ6 ABC transporter HHJ27_RS15835 ENOG4105ECW sulfate abc transporter HHJ27_RS15840 ENOG4108I5D sulfate abc transporter HHJ27_RS15845 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HHJ27_RS15850 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HHJ27_RS15865 ENOG4105C5Y PTS System HHJ27_RS15870 ENOG4107S1E Beta-lactamase HHJ27_RS15875 ENOG4105EZR dyp-type peroxidase family protein HHJ27_RS15880 ENOG4105E7K (LipO)protein HHJ27_RS15885 ENOG4105QZU Inner membrane protein YfeZ HHJ27_RS15895 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HHJ27_RS15905 ENOG4108K3Z AraC family transcriptional regulator HHJ27_RS15910 ENOG4108X49 Ethanolamine utilization protein EutK HHJ27_RS15915 ENOG4106D67 ethanolamine utilization protein HHJ27_RS15925 ENOG4105CPD ethanolamine ammonia-lyase HHJ27_RS15930 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HHJ27_RS15935 ENOG4105ENY Ethanolamine utilization protein eutH HHJ27_RS15940 ENOG4105C0A alcohol dehydrogenase HHJ27_RS15945 ENOG4107RWI ethanolamine utilization protein eutJ HHJ27_RS15950 ENOG4108EKI Dehydrogenase HHJ27_RS15955 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HHJ27_RS15960 ENOG4105KNY Microcompartments protein HHJ27_RS15965 ENOG4107WUY phosphate acetyltransferase HHJ27_RS15970 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HHJ27_RS15975 ENOG4105NDK ethanolamine utilization protein HHJ27_RS15980 ENOG4106S4J ethanolamine utilization protein EutP HHJ27_RS15985 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HHJ27_RS15990 ENOG4105C6K Malic enzyme HHJ27_RS15995 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ27_RS16000 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ27_RS16005 ENOG4108PVD exported protein HHJ27_RS16015 ENOG4105BZ8 glutamate synthase HHJ27_RS16020 ENOG4105BZU Histidine kinase HHJ27_RS16025 ENOG4105BZS acriflavin resistance protein HHJ27_RS16035 ENOG4105KUZ arsenate reductase HHJ27_RS16050 ENOG4106KED esterase YpfH HHJ27_RS16060 ENOG4105CGZ zinc metallopeptidase HHJ27_RS16070 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ27_RS16080 ENOG4105RH4 Glycine cleavage system transcriptional repressor HHJ27_RS16085 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HHJ27_RS16090 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HHJ27_RS16095 ENOG4108JPZ Monovalent cation H antiporter subunit D HHJ27_RS16100 ENOG4107TDF Formate hydrogenlyase subunit 4 HHJ27_RS16105 ENOG4105D65 subunit l HHJ27_RS16110 ENOG4107WQX hydrogenase 4 membrane subunit HHJ27_RS16115 ENOG4108JPZ Monovalent cation H antiporter subunit D HHJ27_RS16120 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HHJ27_RS16130 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HHJ27_RS16135 ENOG4105I6X formate hydrogenlyase maturation HHJ27_RS16140 ENOG4108JUA Transcriptional regulator HHJ27_RS16145 ENOG4105TMB Formate nitrite transporter HHJ27_RS16150 ENOG4105C02 permease HHJ27_RS16155 ENOG4105ERG peptidase m48, ste24p HHJ27_RS16160 ENOG4105K89 arsenate reductase HHJ27_RS16165 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HHJ27_RS16170 ENOG4105C2W permease HHJ27_RS16185 ENOG4108V3E phosphoribosylglycinamide formyltransferase HHJ27_RS16190 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HHJ27_RS16195 ENOG4105C9X ppx gppa phosphatase HHJ27_RS16200 ENOG4105BZU Histidine kinase HHJ27_RS16210 ENOG41062G3 Protein of unknown function (DUF2633) HHJ27_RS16215 ENOG4108ZMA Outer membrane lipoprotein HHJ27_RS16220 ENOG41066DY Membrane HHJ27_RS16230 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HHJ27_RS16240 ENOG4105VPD cellular component movement HHJ27_RS16255 ENOG4105N21 Membrane HHJ27_RS16285 ENOG4108JQB penicillin-binding protein 1C HHJ27_RS16290 ENOG4105DN3 alpha-2-macroglobulin domain protein HHJ27_RS16295 ENOG4105KHC sulfurtransferase HHJ27_RS16300 ENOG4105YYA enhanced serine sensitivity protein SseB HHJ27_RS16310 ENOG4105WVQ Fe-S assembly protein IscX HHJ27_RS16315 ENOG4108ZIT Ferredoxin, 2FE-2S HHJ27_RS16335 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HHJ27_RS16355 ENOG4105ECY inositol monophosphatase HHJ27_RS16360 ENOG4107XM9 (LipO)protein HHJ27_RS16365 ENOG4108MN2 Stationary phase inducible protein CsiE HHJ27_RS16370 ENOG4105D8G Major Facilitator superfamily HHJ27_RS16375 ENOG4108W5M transcriptional regulator HHJ27_RS16380 ENOG4105FUY alpha subunit HHJ27_RS16405 ENOG4108SB3 DoxX Family HHJ27_RS16410 ENOG4108ZKT aldose 1-epimerase HHJ27_RS16415 ENOG4105CPQ Dehydrogenase HHJ27_RS16420 ENOG4105CNN ABC, transporter HHJ27_RS16425 ENOG4108F37 ATP-binding component of a transport system HHJ27_RS16430 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HHJ27_RS16435 ENOG4107HQ7 repeat protein HHJ27_RS16440 ENOG4108NZE NAGC-like transcriptional regulator HHJ27_RS16450 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ27_RS16460 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ27_RS16465 ENOG4108SKK alpha helix protein HHJ27_RS16470 ENOG4107WP9 Histidine kinase HHJ27_RS16475 ENOG4108ETH Formylglycinamide ribotide synthetase HHJ27_RS16485 ENOG4108Z6B deaminase HHJ27_RS16490 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HHJ27_RS16495 ENOG4106G6Q Transcriptional regulator HHJ27_RS16500 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HHJ27_RS16515 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HHJ27_RS16535 ENOG4105C3F Signal peptidase i HHJ27_RS16545 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HHJ27_RS16550 ENOG4105VQK sigma E regulatory protein, MucB RseB HHJ27_RS16555 ENOG41069PW sigma-e factor negative regulatory protein HHJ27_RS16560 ENOG4105EMN RNA polymerase sigma factor HHJ27_RS16570 ENOG4108IYU L-aspartate oxidase HHJ27_RS16580 ENOG4105C1J atp-dependent rna helicase HHJ27_RS16585 ENOG41090KR LysR family transcriptional Regulator HHJ27_RS16605 ENOG4105EIB trna rrna methyltransferase HHJ27_RS16610 ENOG4105K63 Thioredoxin HHJ27_RS16615 ENOG4106IUH DTW domain containing protein HHJ27_RS16620 ENOG4105CD5 CoA-binding domain protein HHJ27_RS16625 ENOG4105JIM Phosphatidylserine synthase HHJ27_RS16630 ENOG4105T42 (LipO)protein HHJ27_RS16635 ENOG4105CSH Transporter HHJ27_RS16665 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ27_RS16670 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HHJ27_RS16675 ENOG4105C34 Pseudouridine synthase HHJ27_RS16680 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HHJ27_RS16685 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HHJ27_RS16695 ENOG4105CQC Prephenate dehydratase HHJ27_RS16700 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HHJ27_RS16705 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ27_RS16710 ENOG4105QP9 Protein of unknown function (DUF2799) HHJ27_RS16715 ENOG4108WS1 HHJ27_RS16720 ENOG4108KHX Diguanylate cyclase HHJ27_RS16725 ENOG41090EK ompa motb domain protein HHJ27_RS16750 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HHJ27_RS16755 ENOG4106KVJ cytochrome C assembly protein HHJ27_RS16760 ENOG4108JU6 CBS domain protein HHJ27_RS16775 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HHJ27_RS16780 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ27_RS16790 ENOG4108Z1B Cyclase dehydrase HHJ27_RS16805 ENOG4108MGN ATP-binding component of a transport system HHJ27_RS16830 ENOG4105E54 alpha-amylase HHJ27_RS16840 ENOG4105D5U fad dependent oxidoreductase HHJ27_RS16845 ENOG4105C26 Dehydrogenase HHJ27_RS16850 ENOG4108JPW Aminotransferase HHJ27_RS16855 ENOG4105C85 amino acid HHJ27_RS16860 ENOG4108PVQ transcriptional regulator HHJ27_RS16865 ENOG4109066 lysm domain bon superfamily protein HHJ27_RS16870 ENOG4105VPI YqaE family transport protein HHJ27_RS16875 ENOG41080HT Transcriptional regulator, arsr family HHJ27_RS16880 ENOG4108V62 Rhodanese domain protein HHJ27_RS16885 ENOG4108X73 DNA- binding protein HHJ27_RS16890 ENOG4108RNS Exports L-alanine (By similarity) HHJ27_RS16895 ENOG4108WMJ Protein of unknown function (DUF2002) HHJ27_RS16900 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HHJ27_RS16905 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HHJ27_RS16910 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HHJ27_RS16915 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HHJ27_RS16925 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ27_RS16930 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ27_RS16935 ENOG4108IJ7 Glycine betaine HHJ27_RS16940 ENOG4108HQS Glycine betaine HHJ27_RS16945 ENOG4105GIJ Glycine betaine HHJ27_RS16950 ENOG4105EQR Transposase IS116 IS110 IS902 HHJ27_RS16960 ENOG4108UMN azlc family HHJ27_RS16965 ENOG4105ZED uncharacterized protein ygaH HHJ27_RS16975 ENOG4105NTK Transcriptional repressor Mpra HHJ27_RS16980 ENOG4105CW7 secretion protein, HlyD family HHJ27_RS16985 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ27_RS17000 ENOG4105W39 Membrane HHJ27_RS17005 ENOG4107VXZ Hydrolase HHJ27_RS17035 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HHJ27_RS17055 ENOG4107TH8 cina domain protein HHJ27_RS17060 ENOG4105CVE Lytic murein transglycosylase HHJ27_RS17065 ENOG410787A Pts system, glucitol sorbitol-specific HHJ27_RS17070 ENOG4105DZY Pts system, glucitol sorbitol-specific HHJ27_RS17075 ENOG4105VI0 Pts system, glucitol sorbitol-specific HHJ27_RS17080 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HHJ27_RS17085 ENOG4105J92 DNA-binding transcriptional activator GutM HHJ27_RS17090 ENOG410804X Transcriptional regulator HHJ27_RS17115 ENOG4105C8H hydrogenase maturation protein Hypf HHJ27_RS17120 ENOG4108RC0 Electron transport protein HHJ27_RS17125 ENOG4105DDV Transcriptional regulator (LacI family HHJ27_RS17130 ENOG4105C5Y PTS System HHJ27_RS17135 ENOG4105CS2 ec 3.2.1.21 HHJ27_RS17140 ENOG4108Z3N Transcriptional regulator HHJ27_RS17145 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) HHJ27_RS17150 ENOG4108MG9 hydrogenase 3 maturation protease HHJ27_RS17155 ENOG4105I6X formate hydrogenlyase maturation HHJ27_RS17160 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HHJ27_RS17165 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HHJ27_RS17170 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HHJ27_RS17175 ENOG4107TDF Formate hydrogenlyase subunit 4 HHJ27_RS17180 ENOG4107R30 NADH dehydrogenase HHJ27_RS17185 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HHJ27_RS17190 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HHJ27_RS17195 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HHJ27_RS17200 ENOG4107RSS Hydrogenase accessory protein HypB HHJ27_RS17205 ENOG41083WG hydrogenase assembly chaperone HHJ27_RS17210 ENOG4105CQS hydrogenase expression formation protein HypD HHJ27_RS17215 ENOG4105C45 hydrogenase expression formation protein (HypE) HHJ27_RS17220 ENOG4108JUA Transcriptional regulator HHJ27_RS17230 ENOG4105VXR cytoplasmic protein HHJ27_RS17245 ENOG4105MEW serine threonine protein phosphatase HHJ27_RS17250 ENOG4105MVE transcriptional regulator HHJ27_RS17255 ENOG4105ZXK Dehydrogenase HHJ27_RS17260 ENOG4105G63 Type III effector Hrp-dependent HHJ27_RS17265 ENOG4105FB2 class II Aldolase HHJ27_RS17270 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ27_RS17275 ENOG4105C6Z Gluconate HHJ27_RS17280 ENOG4105KZM cytoplasmic protein HHJ27_RS17285 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HHJ27_RS17290 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HHJ27_RS17300 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ27_RS17305 ENOG4108K5P (LipO)protein HHJ27_RS17340 ENOG4105N0Z inner membrane protein ygbE HHJ27_RS17355 ENOG4105C11 sulfate adenylyltransferase), subunit 2 HHJ27_RS17360 ENOG4108MXK alkaline phosphatase isozyme conversion HHJ27_RS17365 ENOG4105PWE CRISPR-associated protein cas2 HHJ27_RS17370 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HHJ27_RS17380 ENOG4108VWQ crispr-associated protein HHJ27_RS17385 ENOG41060M0 Crispr-associated protein, cse4 family HHJ27_RS17395 ENOG4105CYR Crispr-associated protein, cse1 family HHJ27_RS17400 ENOG4105DTT CRISPR-associated helicase, cas3 HHJ27_RS17405 ENOG4107635 Hok Gef family protein HHJ27_RS17410 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) HHJ27_RS17425 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HHJ27_RS17430 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ27_RS17435 ENOG4105WQV ferredoxin-like protein HHJ27_RS17440 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator HHJ27_RS17450 ENOG4105YBM electron transfer flavoprotein subunit ygcQ HHJ27_RS17455 ENOG4106IKH Electron transfer flavoprotein HHJ27_RS17460 ENOG4105C54 Major Facilitator superfamily HHJ27_RS17465 ENOG4107R3A FAD linked oxidase domain protein HHJ27_RS17470 ENOG4105CHR reductase HHJ27_RS17475 ENOG4108ITV Inner membrane protein yqcE HHJ27_RS17480 ENOG4108CWB sugar kinase ygcE HHJ27_RS17485 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HHJ27_RS17495 ENOG4105HA9 of methanol dehydrogenase type HHJ27_RS17510 ENOG4105DXN mazG family HHJ27_RS17515 ENOG4105MZG transcriptional modulator of maze toxin, mazf HHJ27_RS17520 ENOG4106A2Z transcriptional regulator antitoxin, MazE HHJ27_RS17525 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ27_RS17535 ENOG4105BZU Histidine kinase HHJ27_RS17540 ENOG4105EQX glucarate dehydratase HHJ27_RS17545 ENOG4105EQX glucarate dehydratase HHJ27_RS17550 ENOG4105DJB Major Facilitator Superfamily HHJ27_RS17555 ENOG4105QDK Flavodoxin HHJ27_RS17560 ENOG4105DR9 pseudouridine synthase HHJ27_RS17565 ENOG4105WP7 tRNA pseudouridine synthase C HHJ27_RS17580 ENOG4105EWT decarboxylase family HHJ27_RS17585 ENOG4105C44 Serine transporter HHJ27_RS17590 ENOG4105EJQ L-serine dehydratase HHJ27_RS17600 ENOG4105C0A alcohol dehydrogenase HHJ27_RS17605 ENOG4107W7X Aldolase HHJ27_RS17610 ENOG4105EDR glucose galactose transporter HHJ27_RS17615 ENOG4105EHF Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity) HHJ27_RS17620 ENOG4105CMG Carbohydrate kinase HHJ27_RS17630 ENOG4107EDW L-fucose operon activator HHJ27_RS17640 ENOG4105M08 Membrane HHJ27_RS17645 ENOG4105ETT transcriptional Regulator, LysR family HHJ27_RS17650 ENOG4105M5B (LipO)protein HHJ27_RS17655 ENOG4105C9B Cysteine desulfurase HHJ27_RS17660 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HHJ27_RS17665 ENOG4105CUZ uba thif-type nad fad binding protein HHJ27_RS17670 ENOG4105CA3 membrane-bound lytic murein transglycosylase HHJ27_RS17690 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ27_RS17695 ENOG4108EKC n-acetylglutamate synthase HHJ27_RS17700 ENOG4107QYX exodeoxyribonuclease v alpha HHJ27_RS17705 ENOG4107QKA exodeoxyribonuclease V beta HHJ27_RS17710 ENOG4107QXK peptidase HHJ27_RS17715 ENOG4105DSY exodeoxyribonuclease V, gamma HHJ27_RS17720 ENOG4105RVB Prepilin peptidase dependent protein c HHJ27_RS17725 ENOG4105SEN Protein of unknown function (DUF2509) HHJ27_RS17730 ENOG4105JCS prepilin peptidase dependent protein HHJ27_RS17735 ENOG4105IPU prepilin peptidase dependent protein A HHJ27_RS17750 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HHJ27_RS17765 ENOG4105EE5 Membrane protein terC HHJ27_RS17770 ENOG4105SUV lipoprotein YgdR HHJ27_RS17775 ENOG4105CPC Aldo Keto reductase HHJ27_RS17790 ENOG41060NJ transcriptional regulator HHJ27_RS17800 ENOG4105RQF LysR family Transcriptional regulator HHJ27_RS17810 ENOG4107QNK )-transporter HHJ27_RS17815 ENOG4105CHR reductase HHJ27_RS17825 ENOG4105CHU acetyl-coa acetyltransferase HHJ27_RS17830 ENOG4108MHD transport protein HHJ27_RS17840 ENOG4108K5P (LipO)protein HHJ27_RS17845 ENOG4105C7W Xanthine dehydrogenase HHJ27_RS17850 ENOG4108HR6 Dehydrogenase HHJ27_RS17855 ENOG4108UTP (2Fe-2S)-binding domain protein HHJ27_RS17860 ENOG4108JUB Transcriptional regulator HHJ27_RS17865 ENOG4105IW6 Carbamoyltransferase HHJ27_RS17870 ENOG4107RCH Diaminopropionate ammonia-lyase HHJ27_RS17875 ENOG4107S4Y M20 DapE family protein YgeY HHJ27_RS17880 ENOG4105CD3 dihydroorotase HHJ27_RS17885 ENOG4105C5B carbamate kinase HHJ27_RS17890 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HHJ27_RS17895 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HHJ27_RS17900 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HHJ27_RS17905 ENOG4105BZ8 glutamate synthase HHJ27_RS17910 ENOG4107UUR Chlorohydrolase aminohydrolase HHJ27_RS17915 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HHJ27_RS17920 ENOG4105C7W Xanthine dehydrogenase HHJ27_RS17925 ENOG4105C2W permease HHJ27_RS17930 ENOG4107QUY Guanine deaminase HHJ27_RS17935 ENOG4105C7N Xanthine uracil vitamin C permease HHJ27_RS17940 ENOG4108R8B oxidoreductase Fe-S subunit HHJ27_RS17945 ENOG4105BZ8 glutamate synthase HHJ27_RS17950 ENOG4105C2W permease HHJ27_RS17970 ENOG4105CRK lysyL-tRNA synthetase HHJ27_RS17980 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HHJ27_RS17985 ENOG4105T95 Thiol disulfide interChange protein HHJ27_RS17990 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HHJ27_RS17995 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HHJ27_RS18000 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HHJ27_RS18005 ENOG4105Y75 tpr repeat protein HHJ27_RS18015 ENOG4108UT2 hemolysin iii HHJ27_RS18025 ENOG4105CS2 ec 3.2.1.21 HHJ27_RS18050 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ27_RS18055 ENOG4105D0A hydroxylase HHJ27_RS18060 ENOG4107RAQ aminopeptidase HHJ27_RS18080 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HHJ27_RS18090 ENOG4108JQ1 Dehydrogenase HHJ27_RS18120 ENOG4105MPN Membrane HHJ27_RS18125 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HHJ27_RS18130 ENOG4105D64 Mechanosensitive ion channel HHJ27_RS18135 ENOG4105D2N Aldolase HHJ27_RS18170 ENOG4108JJB ABC transporter HHJ27_RS18175 ENOG4107Z1W Fructose transport system kinase HHJ27_RS18180 ENOG4108R4K DNA-binding, transcriptional regulator HHJ27_RS18185 ENOG4108Q8A Fructose-1,6-bisphosphatase HHJ27_RS18190 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HHJ27_RS18195 ENOG4105CTS PTS system mannitol-specific HHJ27_RS18200 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HHJ27_RS18205 ENOG4105EPW hflc protein HHJ27_RS18210 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ27_RS18215 ENOG4108K0D peptidase, M48 HHJ27_RS18230 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HHJ27_RS18250 ENOG4107QNK )-transporter HHJ27_RS18260 ENOG4105RWS endonuclease I HHJ27_RS18265 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HHJ27_RS18270 ENOG4105D7Z glutathione synthase HHJ27_RS18285 ENOG4105CZX twitching motility protein HHJ27_RS18290 ENOG4105DFA alanine racemase domain protein HHJ27_RS18295 ENOG4108VIA integral membrane protein HHJ27_RS18305 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ27_RS18310 ENOG4105CSA Coproporphyrinogen iii oxidase HHJ27_RS18315 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ27_RS18320 ENOG41069H7 transport system small permease component HHJ27_RS18325 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ27_RS18330 ENOG4106MH3 alpha helix chain HHJ27_RS18335 ENOG4105HDK L-asparaginase HHJ27_RS18340 ENOG4105K33 Periplasmic Protein HHJ27_RS18345 ENOG41090ED Protein with unknown function (DUF469) HHJ27_RS18355 ENOG4105CEN a g-specific adenine glycosylase HHJ27_RS18370 ENOG4105EAA nucleoside HHJ27_RS18375 ENOG4105CXN decarboxylase HHJ27_RS18380 ENOG4108UQV Membrane HHJ27_RS18405 ENOG41067TZ transcriptional regulator, MarR family HHJ27_RS18435 ENOG4105C87 Aminotransferase class I and II HHJ27_RS18440 ENOG4105CI1 PTS System HHJ27_RS18445 ENOG4105D2N Aldolase HHJ27_RS18450 ENOG4105E98 transcriptional regulator DeoR family HHJ27_RS18475 ENOG4107QIJ Aconitate hydratase 2 HHJ27_RS18490 ENOG4105CHY citrate lyase, alpha HHJ27_RS18495 ENOG4105CI0 Citrate lyase HHJ27_RS18505 ENOG4105DUA (citrate (pro-3S)-lyase ligase HHJ27_RS18610 ENOG4107RTG Major Facilitator superfamily HHJ27_RS18615 ENOG4105ENX hydrolase HHJ27_RS18630 ENOG4105F4K antigen 43 HHJ27_RS18655 ENOG4105MFG Antirestriction protein HHJ27_RS18660 ENOG4108YGG dna repair protein HHJ27_RS18670 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ27_RS18700 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ27_RS18705 ENOG4105ECX polysaccharide export HHJ27_RS18710 ENOG4107V1M polysaccharide export protein HHJ27_RS18715 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) HHJ27_RS18720 ENOG4105E12 capsule polysaccharide HHJ27_RS18725 ENOG41084CK capsule polysaccharide HHJ27_RS18730 ENOG41090SZ ABC-2 type transporter HHJ27_RS18765 ENOG4105U1E general secretion pathway protein M HHJ27_RS18785 ENOG4105X5Z General secretion pathway protein I HHJ27_RS18795 ENOG4108VAU general secretion pathway protein G HHJ27_RS18800 ENOG4105D7Q type ii secretion system HHJ27_RS18805 ENOG4107QHF type ii secretion system protein e HHJ27_RS18820 ENOG410765S (LipO)protein HHJ27_RS18830 ENOG4105F88 accessory colonization factor AcfD HHJ27_RS18835 ENOG4105DAA L-lactate HHJ27_RS18840 ENOG4107QP3 malate synthase g HHJ27_RS18845 ENOG4108ZJF Glcg protein HHJ27_RS18850 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ27_RS18855 ENOG4105EU8 FAD linked oxidase domain protein HHJ27_RS18860 ENOG4105CQB FAD linked oxidase domain protein HHJ27_RS18865 ENOG4108KWP DNA-binding transcriptional regulator GlcC HHJ27_RS18875 ENOG4107RCI amp-dependent synthetase and ligase HHJ27_RS18885 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ27_RS18890 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ27_RS18900 ENOG4108M8S permease YjgP YjgQ family protein HHJ27_RS18905 ENOG4108UUE Transcriptional regulator HHJ27_RS18915 ENOG4108S55 polysaccharide biosynthesis protein HHJ27_RS18920 ENOG4106FPV ATP-binding protein YghR HHJ27_RS18925 ENOG4108NDC ATP-binding protein yghS HHJ27_RS18930 ENOG4108GH0 ATP-binding protein yghT HHJ27_RS18935 ENOG4105CJ3 phosphate transporter HHJ27_RS18940 ENOG4106032 Glutathionylspermidine synthase HHJ27_RS18945 ENOG4105CYM Glutathione S-transferase HHJ27_RS18950 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HHJ27_RS18960 ENOG4108WGS hydrogenase 2-specific chaperone HHJ27_RS18965 ENOG4108USZ hydrogenase HHJ27_RS18970 ENOG4105DPX Hydrogenase, large subunit HHJ27_RS18975 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HHJ27_RS18980 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ27_RS18985 ENOG4105E3S small subunit HHJ27_RS18990 ENOG410900S Protein of unknown function (DUF2623) HHJ27_RS19000 ENOG4105CPC Aldo Keto reductase HHJ27_RS19010 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HHJ27_RS19015 ENOG4108ZZF transport protein (ExbD) HHJ27_RS19020 ENOG4105CWK Biopolymer transport protein, ExbB HHJ27_RS19025 ENOG4105C28 cystathionine HHJ27_RS19030 ENOG4108K81 inner membrane protein YghB HHJ27_RS19035 ENOG4105CF7 AraC family transcriptional regulator HHJ27_RS19040 ENOG4108I6A alcohol dehydrogenase HHJ27_RS19045 ENOG4105CV8 reductase HHJ27_RS19050 ENOG4105ZKC Conserved Protein HHJ27_RS19060 ENOG4105CCT upf0313 protein HHJ27_RS19065 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HHJ27_RS19070 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HHJ27_RS19075 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ27_RS19080 ENOG4108J59 Extracellular solute-binding protein, family 5 HHJ27_RS19085 ENOG4105F4I Transcriptional regulator HHJ27_RS19090 ENOG4105H4F exported protein HHJ27_RS19095 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ27_RS19100 ENOG4105DHQ Histidine kinase HHJ27_RS19105 ENOG4107DEU Inner membrane protein YgiZ HHJ27_RS19110 ENOG4105NF4 modulator of drug activity HHJ27_RS19115 ENOG4105VRH Antibiotic biosynthesis monooxygenase HHJ27_RS19120 ENOG4106KNT transcriptional regulator HHJ27_RS19130 ENOG4105EHG Permease protein HHJ27_RS19135 ENOG4105DQ5 transport system permease protein HHJ27_RS19140 ENOG4105E0A ABC, transporter HHJ27_RS19150 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ27_RS19155 ENOG4105IPS esterase HHJ27_RS19160 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HHJ27_RS19165 ENOG4108SX3 cytoplasmic protein HHJ27_RS19170 ENOG41087AY ADP-Ribose pyrophosphatase HHJ27_RS19175 ENOG4105DFG type I secretion outer membrane protein HHJ27_RS19185 ENOG4106032 Glutathionylspermidine synthase HHJ27_RS19190 ENOG4108MR7 Arylsulfotransferase HHJ27_RS19195 ENOG4108N92 Thiol disulfide Interchange Protein HHJ27_RS19205 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HHJ27_RS19225 ENOG4105W0Z cytoplasmic protein HHJ27_RS19235 ENOG4105PV3 Inner membrane protein yqiJ HHJ27_RS19240 ENOG4107S78 Band 7 protein HHJ27_RS19265 ENOG4105I7R Adenylate cyclase HHJ27_RS19270 ENOG4106MWK domain protein HHJ27_RS19285 ENOG4107ZVW dihydroneopterin aldolase HHJ27_RS19295 ENOG4105EJC lysr family transcriptional regulator HHJ27_RS19300 ENOG4106DSS Tartrate dehydratase subunit alpha HHJ27_RS19305 ENOG4107GFK fumarate HHJ27_RS19310 ENOG4107QPK )-transporter HHJ27_RS19315 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) HHJ27_RS19325 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HHJ27_RS19330 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ27_RS19345 ENOG4105Q26 Siderophore-interacting protein HHJ27_RS19350 ENOG4105NTW Transcriptional regulator HHJ27_RS19365 ENOG4108Y51 tRNA-binding protein HHJ27_RS19370 ENOG4105CQ4 Transcriptional regulator HHJ27_RS19375 ENOG4105CNT hydrolase family 2 HHJ27_RS19380 ENOG4105FK9 beta-D-galactosidase beta subunit HHJ27_RS19385 ENOG4105E5D amino acid HHJ27_RS19390 ENOG4107W6W Conserved Protein HHJ27_RS19395 ENOG4107WCA isomerase HHJ27_RS19405 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ27_RS19415 ENOG4108VKG metal-dependent hydrolase HHJ27_RS19420 ENOG4108UB4 uncharacterized protein ygjQ HHJ27_RS19425 ENOG4105EE0 oxidoreductase HHJ27_RS19430 ENOG4105DU1 integral membrane protein, terc HHJ27_RS19435 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) HHJ27_RS19440 ENOG4105P66 Membrane HHJ27_RS19445 ENOG4105CTX dehydratase HHJ27_RS19455 ENOG4105DPW Major facilitator superfamily MFS_1 HHJ27_RS19460 ENOG4107YCY Transcriptional regulator HHJ27_RS19465 ENOG4106W5V Membrane HHJ27_RS19470 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HHJ27_RS19475 ENOG4105WAY exported protein HHJ27_RS19480 ENOG4105NE1 Conserved Protein HHJ27_RS19485 ENOG41090KG Inner membrane protein YqjE HHJ27_RS19490 ENOG4105YJD HHJ27_RS19495 ENOG4108VBZ doxx family HHJ27_RS19500 ENOG4105CHF Glutathione S-transferase HHJ27_RS19505 ENOG4105KAF membrAne HHJ27_RS19510 ENOG4105KAF membrAne HHJ27_RS19515 ENOG4105CWB LysR family transcriptional Regulator HHJ27_RS19520 ENOG4108CNN domain protein HHJ27_RS19525 ENOG4106D80 Uncharacterized protein YhaL HHJ27_RS19535 ENOG4105C44 Serine transporter HHJ27_RS19540 ENOG4105EJQ L-serine dehydratase HHJ27_RS19545 ENOG4105KME endoribonuclease L-psp HHJ27_RS19550 ENOG4105C6N Formate acetyltransferase HHJ27_RS19555 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HHJ27_RS19560 ENOG4108MST Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity) HHJ27_RS19565 ENOG4105C7B Threonine dehydratase HHJ27_RS19570 ENOG410811B TRANSCRIPTIONal HHJ27_RS19595 ENOG4105BZW Glycerate kinase HHJ27_RS19600 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ27_RS19610 ENOG4105DJB Major Facilitator Superfamily HHJ27_RS19615 ENOG4105CTX dehydratase HHJ27_RS19620 ENOG4105ZEG Suppressor protein HHJ27_RS19625 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression HHJ27_RS19630 ENOG4105E98 transcriptional regulator DeoR family HHJ27_RS19640 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HHJ27_RS19650 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ27_RS19655 ENOG4108YTN IIa component HHJ27_RS19660 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ27_RS19665 ENOG4105E70 isomerase HHJ27_RS19675 ENOG4108UZY PTS System HHJ27_RS19680 ENOG4105ETZ PTS System HHJ27_RS19685 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ27_RS19690 ENOG4106HBN Galactosamine-6-phosphate isomerase HHJ27_RS19695 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HHJ27_RS19715 ENOG4105W4M Transport-associated protein HHJ27_RS19720 ENOG4107S21 permease HHJ27_RS19725 ENOG4105K4T epimerase HHJ27_RS19730 ENOG4107R7Y intracellular protease Pfpi family HHJ27_RS19745 ENOG4108YYD acetyltransferase HHJ27_RS19765 ENOG4105DEN Luciferase family HHJ27_RS19770 ENOG4105CIC tryptophan-specific transport protein HHJ27_RS19775 ENOG4105C1J atp-dependent rna helicase HHJ27_RS19815 ENOG4105CHV Transcription elongation factor NusA HHJ27_RS19835 ENOG4105DIJ Phosphoethanolamine transferase HHJ27_RS19845 ENOG4105NTZ Preprotein translocase subunit SecG HHJ27_RS19855 ENOG4105EEI dihydropteroate synthase HHJ27_RS19860 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HHJ27_RS19870 ENOG4105HBR Rna-binding protein HHJ27_RS19875 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HHJ27_RS19880 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HHJ27_RS19885 ENOG4108RS6 transposase HHJ27_RS19895 ENOG4105QYV Membrane HHJ27_RS19910 ENOG4105EAH synthase HHJ27_RS19915 ENOG4105HVQ Regulatory factor of maltose metabolism HHJ27_RS19925 ENOG4105VFK BolA family HHJ27_RS19930 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HHJ27_RS19935 ENOG4105E3I toluene tolerance HHJ27_RS19940 ENOG4107PE3 Mammalian cell entry related domain protein HHJ27_RS19945 ENOG4105CY3 ABC transporter, permease HHJ27_RS19950 ENOG4105DHJ ABC, transporter HHJ27_RS19955 ENOG4105FEU K -dependent Na -Ca exchanger HHJ27_RS19960 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ27_RS19965 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase HHJ27_RS19970 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HHJ27_RS19975 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HHJ27_RS19980 ENOG4108IUZ ABC transporter HHJ27_RS19985 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ27_RS19990 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HHJ27_RS19995 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HHJ27_RS20005 ENOG41080Z8 PHOSPHOCARRIER protein HHJ27_RS20010 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HHJ27_RS20020 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HHJ27_RS20025 ENOG4105BZU Histidine kinase HHJ27_RS20030 ENOG4105N5T Radical SAM Protein HHJ27_RS20035 ENOG4105CBC glutamate synthase HHJ27_RS20040 ENOG4105BZ8 glutamate synthase HHJ27_RS20045 ENOG4105DFS Conserved Protein HHJ27_RS20050 ENOG4108R66 Conserved Protein HHJ27_RS20065 ENOG4105JHE Major Facilitator Superfamily HHJ27_RS20080 ENOG4105CEE C4-dicarboxylate transporter HHJ27_RS20085 ENOG4105KB2 stringent starvation protein b HHJ27_RS20090 ENOG4107MKT Stringent starvation protein a HHJ27_RS20105 ENOG4105D6Z AFG1 family ATPase HHJ27_RS20110 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HHJ27_RS20115 ENOG4105C0H protease HHJ27_RS20120 ENOG4105C0H protease HHJ27_RS20135 ENOG4105RID UPF0379 protein yhcN HHJ27_RS20140 ENOG4105UNR (Barnase) inhibitor HHJ27_RS20155 ENOG4105ZQC membrane protein AaeX HHJ27_RS20160 ENOG4105CR8 Transcriptional regulator HHJ27_RS20165 ENOG4105D1U peptidase U62 modulator of DNA gyrase HHJ27_RS20170 ENOG4105QD6 exported protein HHJ27_RS20175 ENOG4105C03 ribonuclease HHJ27_RS20185 ENOG4105VQ7 Rod shape-determining protein MreD HHJ27_RS20190 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HHJ27_RS20200 ENOG41062P1 Diguanylate cyclase phosphodiesterase HHJ27_RS20205 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HHJ27_RS20210 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HHJ27_RS20215 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HHJ27_RS20220 ENOG4105RG0 Membrane HHJ27_RS20225 ENOG4108IA2 Sodium pantothenate symporter HHJ27_RS20235 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ27_RS20245 ENOG4105CEC DNA methylase N-4 N-6 HHJ27_RS20250 ENOG41061ME transport protein HHJ27_RS20255 ENOG4108XG4 DNA-binding transcriptional regulator HHJ27_RS20260 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ27_RS20265 ENOG4105BZS acriflavin resistance protein HHJ27_RS20270 ENOG4105XCM membrane LIPOPROTEIN HHJ27_RS20280 ENOG4105EZ7 amino acid ABC transporter HHJ27_RS20285 ENOG4105DRP amino acid AbC transporter HHJ27_RS20290 ENOG4105CDA abc transporter atp-binding protein HHJ27_RS20335 ENOG4108Z0R Transferase HHJ27_RS20340 ENOG4105SG3 Protein of unknown function (DUF1488) HHJ27_RS20355 ENOG4108WI1 Dna topoisomerase HHJ27_RS20365 ENOG4105C79 DNA protecting protein DprA HHJ27_RS20385 ENOG4105C1A potassium transporter peripheral membrane HHJ27_RS20395 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HHJ27_RS20400 ENOG4105W1Y Transcriptional regulator HHJ27_RS20405 ENOG4105VTS DnaJ-like, subfamily C HHJ27_RS20435 ENOG41067V7 50S ribosomal protein L36 HHJ27_RS20440 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HHJ27_RS20485 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) HHJ27_RS20530 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HHJ27_RS20555 ENOG4108UQY Iron-storage protein HHJ27_RS20560 ENOG4105W53 bacterioferritin-associated ferredoxin HHJ27_RS20585 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) HHJ27_RS20590 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) HHJ27_RS20600 ENOG4105WWK YheO domain protein HHJ27_RS20605 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ27_RS20615 ENOG4108YZY peptidylprolyl cis-trans isomerase HHJ27_RS20620 ENOG4105VKU nucleicacid-binding protein HHJ27_RS20635 ENOG4105C5H ABC transporter HHJ27_RS20640 ENOG4105DNZ Alpha Beta Hydrolase HHJ27_RS20650 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HHJ27_RS20655 ENOG4108UKZ OsmC family HHJ27_RS20665 ENOG410613R integral membrane protein, YccS YhfK family HHJ27_RS20670 ENOG4105C8Y Acetylornithine aminotransferase HHJ27_RS20675 ENOG4105DDQ anthranilate synthase HHJ27_RS20680 ENOG4105MZU cell filamentation protein HHJ27_RS20690 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ27_RS20700 ENOG4107QZF nitrite reductase NADPH large subunit HHJ27_RS20705 ENOG4105WZK nitrite reductase NADPH small subunit HHJ27_RS20710 ENOG4107V9H nitrite transporter HHJ27_RS20720 ENOG4105VYH HHJ27_RS20725 ENOG4106PKC pyridoxal phosphate binding HHJ27_RS20730 ENOG4106M0N transport system permease protein HHJ27_RS20735 ENOG4105MUZ Protein of unknown function DUF2620 HHJ27_RS20740 ENOG41080QX K07048 phosphotriesterase-related protein HHJ27_RS20745 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HHJ27_RS20750 ENOG4108626 Racemase HHJ27_RS20755 ENOG4105RMW regulation of transcription, DNA-dependent HHJ27_RS20760 ENOG4108M21 HHJ27_RS20765 ENOG4105C31 Tryptophanyl-tRNA synthetase HHJ27_RS20770 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HHJ27_RS20775 ENOG4105DJV ribulose-phosphate 3-epimerase HHJ27_RS20780 ENOG4105DFE Dna adenine methylase HHJ27_RS20785 ENOG4105EGB membrane protein DamX HHJ27_RS20800 ENOG4105E4G Type IV pilus HHJ27_RS20805 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HHJ27_RS20810 ENOG4105XPX DNA utilization protein HofO HHJ27_RS20815 ENOG41065NF Fimbrial assembly family protein HHJ27_RS20820 ENOG4108U1Q Pilus assembly protein HHJ27_RS20825 ENOG4108JQC penicillin-binding protein 1A HHJ27_RS20830 ENOG4107RK2 ADP-ribose diphosphatase NudE HHJ27_RS20835 ENOG4105DQY intracellular growth attenuator HHJ27_RS20840 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HHJ27_RS20845 ENOG4105VEJ Heat shock protein HHJ27_RS20855 ENOG4108MAJ Membrane HHJ27_RS20875 ENOG4105E0F Histidine kinase HHJ27_RS20885 ENOG4108RRZ Transcription elongation factor GreB HHJ27_RS20890 ENOG4105BZM domain protein HHJ27_RS20895 ENOG4105XFK Ferrous iron transport protein A HHJ27_RS20900 ENOG4105CE1 Ferrous iron transport protein b HHJ27_RS20910 ENOG4105DNE Transposase HHJ27_RS20920 ENOG4105MJ2 Competence protein HHJ27_RS20930 ENOG4105C6Z Gluconate HHJ27_RS20935 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HHJ27_RS20940 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ27_RS20955 ENOG4105E0Y RtcB Protein HHJ27_RS20960 ENOG4105CYB regulatoR HHJ27_RS20965 ENOG4105E98 transcriptional regulator DeoR family HHJ27_RS20980 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HHJ27_RS21000 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ27_RS21020 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) HHJ27_RS21025 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ27_RS21030 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HHJ27_RS21040 ENOG4105C9U ATP-dependent DNA helicase RecQ HHJ27_RS21045 ENOG4105C6Z Gluconate HHJ27_RS21050 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HHJ27_RS21055 ENOG4105DIQ Transcriptional regulator HHJ27_RS21060 ENOG4105C2I pirin domain protein HHJ27_RS21065 ENOG4105D9R oxidoreductase HHJ27_RS21070 ENOG4105WCN acetyltransferase HHJ27_RS21075 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ27_RS21090 ENOG4106FA4 HHJ27_RS21095 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HHJ27_RS21100 ENOG4105WC8 Conserved Protein HHJ27_RS21105 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HHJ27_RS21115 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component HHJ27_RS21120 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component HHJ27_RS21125 ENOG4105BZ7 extracellular solute-binding protein family 1 HHJ27_RS21135 ENOG4108IV0 ABC, transporter HHJ27_RS21140 ENOG4105C0Z ABC transporter HHJ27_RS21145 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HHJ27_RS21150 ENOG4105C32 Amino acid ABC transporter (Permease) HHJ27_RS21155 ENOG4105CP9 extracellular ligand-binding receptor HHJ27_RS21160 ENOG4105U59 -acetyltransferase HHJ27_RS21165 ENOG4105CP9 extracellular ligand-binding receptor HHJ27_RS21170 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ27_RS21175 ENOG4105CRP Part of the ABC transporter FtsEX involved in HHJ27_RS21180 ENOG4105CAK Cell division ATP-binding protein ftsE HHJ27_RS21185 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HHJ27_RS21190 ENOG4106H78 methyltransferase HHJ27_RS21195 ENOG4105MG3 Membrane HHJ27_RS21205 ENOG4107FS9 Membrane HHJ27_RS21220 ENOG4105EX9 Membrane HHJ27_RS21225 ENOG4108W1V Lipoprotein HHJ27_RS21230 ENOG4105F9N Major Facilitator Superfamily HHJ27_RS21235 ENOG4105DSF transport protein HHJ27_RS21240 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HHJ27_RS21245 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HHJ27_RS21250 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ27_RS21255 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ27_RS21260 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS21265 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS21275 ENOG4105CNA YD repeat protein HHJ27_RS21280 ENOG4106R09 HHJ27_RS21295 ENOG4105CNA YD repeat protein HHJ27_RS21305 ENOG4105NUP lyase containing HEAT-repeat HHJ27_RS21330 ENOG4105CMI transporter HHJ27_RS21335 ENOG4105CJ1 ABC, transporter HHJ27_RS21340 ENOG4105D0S secretion protein (HlyD HHJ27_RS21355 ENOG4107UNS conserved inner membrane protein HHJ27_RS21360 ENOG4105CBX hi0933 family HHJ27_RS21365 ENOG4105CJ3 phosphate transporter HHJ27_RS21380 ENOG4105DUX Transporter HHJ27_RS21390 ENOG4105DGW oligopeptidase A HHJ27_RS21395 ENOG4105D6S protein involved in catabolism of external DNA HHJ27_RS21400 ENOG4105DC8 reductase HHJ27_RS21410 ENOG4105KBH arsR family transcriptional regulator HHJ27_RS21415 ENOG4107R5R arsenical pump membrane protein HHJ27_RS21420 ENOG4105K89 arsenate reductase HHJ27_RS21440 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ27_RS21450 ENOG4106QJH hemin transport protein HHJ27_RS21455 ENOG4107ENK receptor HHJ27_RS21460 ENOG4107R4I Periplasmic binding protein HHJ27_RS21465 ENOG4105D4P Coproporphyrinogen iii oxidase HHJ27_RS21470 ENOG41090JE Utilization Protein HHJ27_RS21480 ENOG4105EHG Permease protein HHJ27_RS21485 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS21490 ENOG4105KT7 mgtC SapB transporter HHJ27_RS21495 ENOG4105XXV Acid-resistance protein HHJ27_RS21500 ENOG41060V2 Acid-resistance protein HHJ27_RS21505 ENOG4108YK4 Acid-resistance membrane protein HHJ27_RS21510 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HHJ27_RS21520 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ27_RS21525 ENOG4105BZS acriflavin resistance protein HHJ27_RS21540 ENOG4105CVK Glutamate decarboxylase HHJ27_RS21545 ENOG4105CA0 peroxidase HHJ27_RS21555 ENOG4106S2D Transcriptional regulator HHJ27_RS21560 ENOG4105CBN LysR family transcriptional regulator HHJ27_RS21565 ENOG4107H3J ribonuclease HHJ27_RS21570 ENOG4105CSH Transporter HHJ27_RS21575 ENOG41066T0 asmA family HHJ27_RS21580 ENOG4105CMB EAL domain-containing protein HHJ27_RS21590 ENOG4105CS0 peptidase HHJ27_RS21600 ENOG4105BZU Histidine kinase HHJ27_RS21605 ENOG4105EJG cellulose synthase HHJ27_RS21610 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HHJ27_RS21615 ENOG4107EEX Cellulose synthase regulator protein HHJ27_RS21620 ENOG4107QZ7 Cellulose synthase catalytic subunit HHJ27_RS21630 ENOG410661M cytoplasmic protein HHJ27_RS21635 ENOG4105U74 cellulose biosynthesis protein BcsE HHJ27_RS21640 ENOG4105WQA Cellulose biosynthesis protein BcsF HHJ27_RS21645 ENOG4105D1V cellulose synthase operon protein YhjU HHJ27_RS21665 ENOG4105C44 Serine transporter HHJ27_RS21670 ENOG4108JQ7 (ABC) transporter HHJ27_RS21675 ENOG4105C3U ABC transporter HHJ27_RS21680 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ27_RS21685 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ27_RS21690 ENOG4105DEF Extracellular solute-binding protein, family 5 HHJ27_RS21710 ENOG4105DIJ Phosphoethanolamine transferase HHJ27_RS21715 ENOG4105FCD Major Facilitator HHJ27_RS21720 ENOG4105EAX Putative lipase HHJ27_RS21725 ENOG4108R3E Dna-3-methyladenine glycosylase i HHJ27_RS21730 ENOG4105HNP -acetyltransferase HHJ27_RS21735 ENOG4107QY8 reductase HHJ27_RS21740 ENOG4108ZG0 Ompa motb domain protein HHJ27_RS21745 ENOG4105C5I Dehydrogenase HHJ27_RS21750 ENOG4106JH6 (LipO)protein HHJ27_RS21755 ENOG4105MVF Transcriptional regulator HHJ27_RS21765 ENOG41060TC Hok gef cell toxic protein HHJ27_RS21790 ENOG4105MEV Acyl-transferase HHJ27_RS21795 ENOG4108Z12 YiaAB two helix domain-containing protein HHJ27_RS21800 ENOG410688U Inner membrane protein yiaB HHJ27_RS21805 ENOG4105CMG Carbohydrate kinase HHJ27_RS21815 ENOG4105DFW ABC transporter HHJ27_RS21825 ENOG4108HWW ABC transporter HHJ27_RS21830 ENOG4105T16 Transcriptional regulator (AraC family) HHJ27_RS21835 ENOG4108UR8 BAX protein HHJ27_RS21840 ENOG4107T9C Alpha amylase catalytic region HHJ27_RS21845 ENOG4105JKW Valine--pyruvate aminotransferase HHJ27_RS21850 ENOG4108XIB electron transport protein ysaA HHJ27_RS21855 ENOG4105J4Q Transcriptional regulator HHJ27_RS21865 ENOG4108R66 Conserved Protein HHJ27_RS21870 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HHJ27_RS21875 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ27_RS21880 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ27_RS21885 ENOG4105CMG Carbohydrate kinase HHJ27_RS21890 ENOG4105H6Q decarboxylase HHJ27_RS21895 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HHJ27_RS21900 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ27_RS21910 ENOG4105CT4 transporter HHJ27_RS21920 ENOG4105GNX MltA-interacting MipA family protein HHJ27_RS21925 ENOG4108Q2M Transcriptional regulator HHJ27_RS21930 ENOG4105EFX secretion protein, HlyD family HHJ27_RS21935 ENOG4105KK7 inner membrane protein YiaW HHJ27_RS21945 ENOG4105C26 Dehydrogenase HHJ27_RS21950 ENOG4105C0A alcohol dehydrogenase HHJ27_RS21955 ENOG4105EM7 Selenocysteine-specific translation elongation factor HHJ27_RS21965 ENOG4108U78 Glutathione S-transferase HHJ27_RS21970 ENOG4105CNA YD repeat protein HHJ27_RS21985 ENOG4105EFX secretion protein, HlyD family HHJ27_RS21990 ENOG4105FP6 Protein of unknown function (DUF3302) HHJ27_RS21995 ENOG4105CTS PTS system mannitol-specific HHJ27_RS22005 ENOG4105E61 Mannitol repressor protein HHJ27_RS22015 ENOG4108YYI Protein of unknown function (DUF2810) HHJ27_RS22020 ENOG4108WY4 inner membrane lipoprotein HHJ27_RS22030 ENOG4105DAA L-lactate HHJ27_RS22035 ENOG41073TP transcriptional regulator HHJ27_RS22045 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HHJ27_RS22050 ENOG4105D7W serine acetyltransferase HHJ27_RS22065 ENOG4105VW4 glutaredoxin 3 HHJ27_RS22070 ENOG4107YZP Rhodanese domain protein HHJ27_RS22080 ENOG41063SB peptidase HHJ27_RS22085 ENOG4105PXI polysaccharide deacetylase HHJ27_RS22090 ENOG4105K64 Glycosyl transferase, family 2 HHJ27_RS22100 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ27_RS22110 ENOG4105XA0 heptosyltransferase ii HHJ27_RS22115 ENOG4105D16 lipopolysaccharide heptosyltransferase i HHJ27_RS22130 ENOG4105X1N Glycosyl transferase family 8 HHJ27_RS22140 ENOG4105X1N Glycosyl transferase family 8 HHJ27_RS22145 ENOG4106AH0 Glycosyl Transferase HHJ27_RS22150 ENOG4107543 (lipo)polysaccharide HHJ27_RS22155 ENOG4107RJ7 Glycosyl transferase (Group 1 HHJ27_RS22160 ENOG4105DKP glycosyl transferase, family 9 HHJ27_RS22165 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HHJ27_RS22175 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) HHJ27_RS22185 ENOG4105KDC 50s ribosomal protein l28 HHJ27_RS22195 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HHJ27_RS22200 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) HHJ27_RS22220 ENOG4105DSJ YicC domain protein HHJ27_RS22225 ENOG4105F5P DNA-damage-inducible protein d HHJ27_RS22230 ENOG4105EN6 Membrane HHJ27_RS22240 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HHJ27_RS22250 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ27_RS22255 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HHJ27_RS22260 ENOG4105CB5 ATP-dependent DNA helicase recG HHJ27_RS22265 ENOG4105D6U Sodium Glutamate Symporter HHJ27_RS22270 ENOG4105C2W permease HHJ27_RS22275 ENOG4105JV1 AsmA family HHJ27_RS22285 ENOG4105DKQ ROK family HHJ27_RS22295 ENOG4105D2N Aldolase HHJ27_RS22300 ENOG4105DM4 PTS System HHJ27_RS22305 ENOG4108YRF PTS System HHJ27_RS22310 ENOG4105DM4 PTS System HHJ27_RS22315 ENOG4105ETD TRANSCRIPTIONal HHJ27_RS22320 ENOG4105CJQ hydrolase, family 31 HHJ27_RS22325 ENOG4105CT4 transporter HHJ27_RS22340 ENOG4105S8Q sugar efflux transporter HHJ27_RS22345 ENOG4108UZ3 Transporter HHJ27_RS22350 ENOG4105D01 (LipO)protein HHJ27_RS22355 ENOG4105T8A Uncharacterized protein YicS HHJ27_RS22380 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC HHJ27_RS22385 ENOG4108YAB Invasion protein HHJ27_RS22390 ENOG4105TNG K13735 adhesin invasin HHJ27_RS22410 ENOG4108SAJ Protein of unknown function (DUF1198) HHJ27_RS22415 ENOG4105C7N Xanthine uracil vitamin C permease HHJ27_RS22425 ENOG4108RS6 transposase HHJ27_RS22430 ENOG4105CXY transporter HHJ27_RS22435 ENOG4105CXY transporter HHJ27_RS22440 ENOG4105BZU Histidine kinase HHJ27_RS22445 ENOG4108KX4 response regulator HHJ27_RS22460 ENOG4105M71 acetolactate synthase 1 regulatory subunit HHJ27_RS22465 ENOG4105C7K acetolactate synthase HHJ27_RS22480 ENOG4105E5M Multidrug resistance protein D HHJ27_RS22485 ENOG4105J13 transcriptional regulator HHJ27_RS22490 ENOG4105JP4 Inner membrane protein yidG HHJ27_RS22495 ENOG4105VG5 Membrane HHJ27_RS22500 ENOG4106DRA Inner membrane protein YidI HHJ27_RS22505 ENOG4105CBG Sulfatase HHJ27_RS22510 ENOG4107RUZ Sss sodium solute transporter superfamily HHJ27_RS22515 ENOG4108AHD Transcriptional regulator HHJ27_RS22520 ENOG4105F8D glycoside hydrolase family 4 HHJ27_RS22525 ENOG4105CI1 PTS System HHJ27_RS22530 ENOG4105FDP GntR family transcriptional regulator HHJ27_RS22550 ENOG4105R2A (LipO)protein HHJ27_RS22555 ENOG4105D99 atp gtp-binding protein HHJ27_RS22565 ENOG4105DJB Major Facilitator Superfamily HHJ27_RS22575 ENOG4108RTU Aldolase HHJ27_RS22580 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HHJ27_RS22585 ENOG4105EMF GntR family transcriptional regulator HHJ27_RS22590 ENOG410657R replicase EC 2.7 HHJ27_RS22595 ENOG410667J hydrolase HHJ27_RS22600 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HHJ27_RS22605 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ27_RS22615 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HHJ27_RS22630 ENOG4105VG0 50S ribosomal protein l34 HHJ27_RS22670 ENOG4108P6C Tryptophan transporter of low affinity HHJ27_RS22685 ENOG4105E8Q phosphopantetheinyl transferase HHJ27_RS22690 ENOG4108YYH Nadph-dependent fmn reductase HHJ27_RS22695 ENOG4105C7N Xanthine uracil vitamin C permease HHJ27_RS22700 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HHJ27_RS22720 ENOG4108UTW Plays a role in the regulation of phosphate uptake HHJ27_RS22725 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HHJ27_RS22730 ENOG4105E2Z phosphate ABC transporter (Permease HHJ27_RS22735 ENOG4105C8U phosphate abc transporter HHJ27_RS22740 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HHJ27_RS22745 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HHJ27_RS22795 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HHJ27_RS22810 ENOG4105QTB Flavodoxin HHJ27_RS22815 ENOG4108VVK transcriptional Regulator, AsnC HHJ27_RS22845 ENOG4105C2J ABC transporter HHJ27_RS22850 ENOG4105CNN ABC, transporter HHJ27_RS22855 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ27_RS22860 ENOG4108RVA ribokinase HHJ27_RS22865 ENOG4105ETE Transcriptional regulator (LacI family HHJ27_RS22870 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ27_RS22875 ENOG4107EJG GntR family transcriptional regulator HHJ27_RS22915 ENOG4108WFC UPF0438 protein yifE HHJ27_RS22920 ENOG4105C0P Mg chelatase subunit ChlI HHJ27_RS22940 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HHJ27_RS22945 ENOG4105CM2 brancheD-chain amino acid aminotransferase HHJ27_RS22955 ENOG4105C7B Threonine dehydratase HHJ27_RS22960 ENOG4105EMY transcriptional regulator HHJ27_RS22970 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HHJ27_RS22980 ENOG4105C4R Atp-dependent dna helicase HHJ27_RS23005 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HHJ27_RS23010 ENOG4105ESV Glycosyl transferase, family 4 HHJ27_RS23015 ENOG4105SFE lipopolysaccharide biosynthesis protein HHJ27_RS23020 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HHJ27_RS23025 ENOG4107QQG Dehydrogenase HHJ27_RS23030 ENOG4105C1B dTDP-glucose 4-6-dehydratase HHJ27_RS23035 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HHJ27_RS23040 ENOG4108WJ1 acetyltransferase HHJ27_RS23045 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HHJ27_RS23050 ENOG4105EGZ biosynthesis protein HHJ27_RS23055 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) HHJ27_RS23060 ENOG4105DAD Could be involved in ECA polysaccharide chain elongation (By similarity) HHJ27_RS23070 ENOG4105C85 amino acid HHJ27_RS23095 ENOG4105C4X radical SAM domain protein HHJ27_RS23100 ENOG4105ENH Sulfatase HHJ27_RS23105 ENOG410601J HemY protein HHJ27_RS23110 ENOG4105ECF c-methyltransferase HHJ27_RS23115 ENOG41076E6 Uroporphyrinogen-III Synthase HHJ27_RS23125 ENOG4107T0K Adenylate cyclase HHJ27_RS23140 ENOG4105S7Z (LipO)protein HHJ27_RS23150 ENOG4105CT0 Protein of unknown function, DUF484 HHJ27_RS23160 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HHJ27_RS23165 ENOG4105C4R Atp-dependent dna helicase HHJ27_RS23170 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase HHJ27_RS23180 ENOG4107QUT magnesium and cobalt transport protein CorA HHJ27_RS23195 ENOG4105FR1 rard protein HHJ27_RS23200 ENOG4108VUY thioesterase Superfamily protein HHJ27_RS23205 ENOG4105HDD phospholipase HHJ27_RS23210 ENOG4105C9U ATP-dependent DNA helicase RecQ HHJ27_RS23215 ENOG4105CCF Lysine exporter protein (Lyse ygga) HHJ27_RS23220 ENOG410829K Lysine exporter protein (Lyse ygga) HHJ27_RS23225 ENOG4108EUD Lysophospholipase HHJ27_RS23230 ENOG4105DQF Hydrolase HHJ27_RS23235 ENOG4105EMK carboxylate amino acid amine transporter HHJ27_RS23240 ENOG4105DZ2 Transcriptional regulator HHJ27_RS23255 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ27_RS23260 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HHJ27_RS23265 ENOG4108I5U Uridine phosphorylase HHJ27_RS23270 ENOG4105CGY Dna recombination protein HHJ27_RS23280 ENOG4105JC1 sterol-binding domain protein HHJ27_RS23290 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HHJ27_RS23295 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HHJ27_RS23300 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HHJ27_RS23310 ENOG4105MDZ Transcriptional activator rfaH HHJ27_RS23315 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HHJ27_RS23320 ENOG4108EX3 reductase HHJ27_RS23325 ENOG4105CHU acetyl-coa acetyltransferase HHJ27_RS23340 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HHJ27_RS23345 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HHJ27_RS23350 ENOG4108RR8 protoporphyrinogen oxidase HHJ27_RS23380 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HHJ27_RS23385 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HHJ27_RS23390 ENOG4105PC1 Conserved Protein HHJ27_RS23395 ENOG4105E27 serine threonine protein kinase HHJ27_RS23400 ENOG4108Z33 Thiol disulfide Interchange Protein HHJ27_RS23410 ENOG4106HNH Acyl-transferase HHJ27_RS23415 ENOG4105C2M dna polymerase I HHJ27_RS23430 ENOG4105D4P Coproporphyrinogen iii oxidase HHJ27_RS23435 ENOG4106FIY HHJ27_RS23440 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ27_RS23445 ENOG4105CUX Signal transduction histidine kinase HHJ27_RS23450 ENOG4105C5F glutamine synthetase HHJ27_RS23455 ENOG4105CI3 gtp-binding protein typa HHJ27_RS23460 ENOG4108K85 Transcriptional regulator HHJ27_RS23465 ENOG4108KHF Resistance protein HHJ27_RS23470 ENOG4105R9B Major Facilitator HHJ27_RS23475 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is HHJ27_RS23480 ENOG4105CT4 transporter HHJ27_RS23485 ENOG4105CT4 transporter HHJ27_RS23490 ENOG4105CJQ hydrolase, family 31 HHJ27_RS23500 ENOG4107WI4 Aldose-1-epimerase HHJ27_RS23505 ENOG4107QKS N-acylglucosamine 2-epimerase HHJ27_RS23510 ENOG4105D2M Aldolase HHJ27_RS23515 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ27_RS23520 ENOG4108MGF sugar kinase HHJ27_RS23525 ENOG4105E98 transcriptional regulator DeoR family HHJ27_RS23530 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HHJ27_RS23545 ENOG4105SUU thioesterase domain HHJ27_RS23560 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system HHJ27_RS23585 ENOG41068KX affects formate dehydrogenase-N HHJ27_RS23595 ENOG4108MG3 formate dehydrogenase HHJ27_RS23600 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ27_RS23620 ENOG4106C3V frv operon regulatory protein HHJ27_RS23625 ENOG4105CN9 Peptidase m42 family protein HHJ27_RS23630 ENOG4105DM4 PTS System HHJ27_RS23635 ENOG41064BA PTS system, fructose-specific, IIA component HHJ27_RS23670 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) HHJ27_RS23680 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ27_RS23690 ENOG4108RPX mosc domain containing protein HHJ27_RS23695 ENOG4105E0F Histidine kinase HHJ27_RS23700 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ27_RS23705 ENOG4105FMW periplasmic HHJ27_RS23710 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HHJ27_RS23795 ENOG4107ENK receptor HHJ27_RS23825 ENOG4108YXQ IS66 Orf2 family protein HHJ27_RS23840 ENOG4105EKQ RNA-directed DNA polymerase HHJ27_RS23860 ENOG41063SR receptor HHJ27_RS23905 ENOG4105EKQ RNA-directed DNA polymerase HHJ27_RS23925 ENOG4108BUD transposase HHJ27_RS23945 ENOG4108BUD transposase HHJ27_RS23980 ENOG4106CQM replication HHJ27_RS23990 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) HHJ27_RS24005 ENOG4105KK6 nuclease HHJ27_RS24015 ENOG4107CBI conjugal transfer fertility inhibition protein HHJ27_RS24020 ENOG4107U2T alpha beta HHJ27_RS24250 ENOG4105FEQ ParB domain protein nuclease HHJ27_RS24315 ENOG41073YN Protein of unknown function (DUF1380)