locus-tag class description HHJ35_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HHJ35_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ35_RS00025 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HHJ35_RS00030 ENOG410667J hydrolase HHJ35_RS00035 ENOG410657R replicase EC 2.7 HHJ35_RS00040 ENOG4105EMF GntR family transcriptional regulator HHJ35_RS00045 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HHJ35_RS00050 ENOG4108RTU Aldolase HHJ35_RS00060 ENOG4105DJB Major Facilitator Superfamily HHJ35_RS00070 ENOG4105D99 atp gtp-binding protein HHJ35_RS00075 ENOG4105R2A (LipO)protein HHJ35_RS00095 ENOG4108AHD Transcriptional regulator HHJ35_RS00100 ENOG4107RUZ Sss sodium solute transporter superfamily HHJ35_RS00110 ENOG4105VG5 Membrane HHJ35_RS00115 ENOG4105JP4 Inner membrane protein yidG HHJ35_RS00120 ENOG4105J13 transcriptional regulator HHJ35_RS00125 ENOG4105E5M Multidrug resistance protein D HHJ35_RS00135 ENOG4105C7K acetolactate synthase HHJ35_RS00140 ENOG4105M71 acetolactate synthase 1 regulatory subunit HHJ35_RS00145 ENOG4108KX4 response regulator HHJ35_RS00150 ENOG4105BZU Histidine kinase HHJ35_RS00155 ENOG4105CXY transporter HHJ35_RS00160 ENOG4105CXY transporter HHJ35_RS00170 ENOG4105C7N Xanthine uracil vitamin C permease HHJ35_RS00175 ENOG4108SAJ Protein of unknown function (DUF1198) HHJ35_RS00185 ENOG4105T8A Uncharacterized protein YicS HHJ35_RS00190 ENOG4105D01 (LipO)protein HHJ35_RS00195 ENOG4108UZ3 Transporter HHJ35_RS00215 ENOG4105CT4 transporter HHJ35_RS00220 ENOG4105CJQ hydrolase, family 31 HHJ35_RS00225 ENOG4105ETD TRANSCRIPTIONal HHJ35_RS00230 ENOG4105DM4 PTS System HHJ35_RS00235 ENOG4108YRF PTS System HHJ35_RS00240 ENOG4105DM4 PTS System HHJ35_RS00245 ENOG4105D2N Aldolase HHJ35_RS00255 ENOG4105DKQ ROK family HHJ35_RS00265 ENOG4105JV1 AsmA family HHJ35_RS00270 ENOG4105C2W permease HHJ35_RS00275 ENOG4105D6U Sodium Glutamate Symporter HHJ35_RS00280 ENOG4105CB5 ATP-dependent DNA helicase recG HHJ35_RS00285 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HHJ35_RS00290 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ35_RS00300 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HHJ35_RS00310 ENOG4105EN6 Membrane HHJ35_RS00315 ENOG4105F5P DNA-damage-inducible protein d HHJ35_RS00435 ENOG4105DSJ YicC domain protein HHJ35_RS00460 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HHJ35_RS00470 ENOG4105KDC 50s ribosomal protein l28 HHJ35_RS00490 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HHJ35_RS00495 ENOG4105DKP glycosyl transferase, family 9 HHJ35_RS00500 ENOG4107RJ7 Glycosyl transferase (Group 1 HHJ35_RS00505 ENOG4107543 (lipo)polysaccharide HHJ35_RS00510 ENOG4106AH0 Glycosyl Transferase HHJ35_RS00515 ENOG4105X1N Glycosyl transferase family 8 HHJ35_RS00525 ENOG4105X1N Glycosyl transferase family 8 HHJ35_RS00530 ENOG4105K64 Glycosyl transferase, family 2 HHJ35_RS00535 ENOG41068PG O-Antigen polymerase HHJ35_RS00540 ENOG4105D16 lipopolysaccharide heptosyltransferase i HHJ35_RS00545 ENOG4105XA0 heptosyltransferase ii HHJ35_RS00555 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ35_RS00565 ENOG4105K64 Glycosyl transferase, family 2 HHJ35_RS00570 ENOG4105PXI polysaccharide deacetylase HHJ35_RS00575 ENOG41063SB peptidase HHJ35_RS00585 ENOG4107YZP Rhodanese domain protein HHJ35_RS00590 ENOG4105VW4 glutaredoxin 3 HHJ35_RS00605 ENOG4105D7W serine acetyltransferase HHJ35_RS00610 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HHJ35_RS00620 ENOG41073TP transcriptional regulator HHJ35_RS00625 ENOG4105DAA L-lactate HHJ35_RS00645 ENOG4108YYI Protein of unknown function (DUF2810) HHJ35_RS00650 ENOG41060ND LF82 chromosome, complete sequence HHJ35_RS00655 ENOG4105E61 Mannitol repressor protein HHJ35_RS00665 ENOG4105CTS PTS system mannitol-specific HHJ35_RS00670 ENOG4105FP6 Protein of unknown function (DUF3302) HHJ35_RS00675 ENOG4105EFX secretion protein, HlyD family HHJ35_RS00680 ENOG4108U78 Glutathione S-transferase HHJ35_RS00690 ENOG4105EM7 Selenocysteine-specific translation elongation factor HHJ35_RS00695 ENOG4105C0A alcohol dehydrogenase HHJ35_RS00705 ENOG4105C26 Dehydrogenase HHJ35_RS00710 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ35_RS00715 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HHJ35_RS00720 ENOG4105H6Q decarboxylase HHJ35_RS00725 ENOG4105CMG Carbohydrate kinase HHJ35_RS00730 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ35_RS00735 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ35_RS00740 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HHJ35_RS00745 ENOG4108M5W HHJ35_RS00750 ENOG4108R66 Conserved Protein HHJ35_RS00760 ENOG4105J4Q Transcriptional regulator HHJ35_RS00765 ENOG4108XIB electron transport protein ysaA HHJ35_RS00770 ENOG4105JKW Valine--pyruvate aminotransferase HHJ35_RS00775 ENOG4107T9C Alpha amylase catalytic region HHJ35_RS00780 ENOG4108UR8 BAX protein HHJ35_RS00785 ENOG4105T16 Transcriptional regulator (AraC family) HHJ35_RS00790 ENOG4108HWW ABC transporter HHJ35_RS00800 ENOG4105DFW ABC transporter HHJ35_RS00810 ENOG4105CMG Carbohydrate kinase HHJ35_RS00815 ENOG410688U Inner membrane protein yiaB HHJ35_RS00820 ENOG4108Z12 YiaAB two helix domain-containing protein HHJ35_RS00825 ENOG4105MEV Acyl-transferase HHJ35_RS00845 ENOG41060TC Hok gef cell toxic protein HHJ35_RS00855 ENOG4105MVF Transcriptional regulator HHJ35_RS00860 ENOG4106JH6 (LipO)protein HHJ35_RS00870 ENOG4108ZG0 Ompa motb domain protein HHJ35_RS00875 ENOG4107QY8 reductase HHJ35_RS00880 ENOG4105HNP -acetyltransferase HHJ35_RS00885 ENOG4108R3E Dna-3-methyladenine glycosylase i HHJ35_RS00890 ENOG4105EAX Putative lipase HHJ35_RS00895 ENOG4105FCD Major Facilitator HHJ35_RS00900 ENOG4105DIJ Phosphoethanolamine transferase HHJ35_RS00910 ENOG4105DEF Extracellular solute-binding protein, family 5 HHJ35_RS00915 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ35_RS00920 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ35_RS00925 ENOG4105C3U ABC transporter HHJ35_RS00930 ENOG4108JQ7 (ABC) transporter HHJ35_RS00935 ENOG4105C44 Serine transporter HHJ35_RS00960 ENOG4107QZ7 Cellulose synthase catalytic subunit HHJ35_RS00965 ENOG4107EEX Cellulose synthase regulator protein HHJ35_RS00970 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HHJ35_RS00975 ENOG4105EJG cellulose synthase HHJ35_RS00980 ENOG4105BZU Histidine kinase HHJ35_RS00990 ENOG4105CS0 peptidase HHJ35_RS00995 ENOG4107SS6 2-dehydro-3-deoxygluconokinase HHJ35_RS01000 ENOG4105CMB EAL domain-containing protein HHJ35_RS01005 ENOG41066T0 asmA family HHJ35_RS01010 ENOG4105CSH Transporter HHJ35_RS01015 ENOG4107H3J ribonuclease HHJ35_RS01020 ENOG4105CBN LysR family transcriptional regulator HHJ35_RS01025 ENOG4106S2D Transcriptional regulator HHJ35_RS01035 ENOG4105CA0 peroxidase HHJ35_RS01040 ENOG4105CVK Glutamate decarboxylase HHJ35_RS01045 ENOG4108NKV transcriptional regulator HHJ35_RS01050 ENOG4105D3F AraC Family Transcriptional Regulator HHJ35_RS01055 ENOG4105BZS acriflavin resistance protein HHJ35_RS01060 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ35_RS01070 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HHJ35_RS01075 ENOG4108YK4 Acid-resistance membrane protein HHJ35_RS01080 ENOG41060V2 Acid-resistance protein HHJ35_RS01085 ENOG4105XXV Acid-resistance protein HHJ35_RS01090 ENOG4105KT7 mgtC SapB transporter HHJ35_RS01100 ENOG4105EHG Permease protein HHJ35_RS01110 ENOG41090JE Utilization Protein HHJ35_RS01115 ENOG4105D4P Coproporphyrinogen iii oxidase HHJ35_RS01125 ENOG4107ENK receptor HHJ35_RS01130 ENOG4106QJH hemin transport protein HHJ35_RS01140 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ35_RS01150 ENOG4105K89 arsenate reductase HHJ35_RS01160 ENOG4105DC8 reductase HHJ35_RS01165 ENOG4105D6S protein involved in catabolism of external DNA HHJ35_RS01170 ENOG4105DGW oligopeptidase A HHJ35_RS01180 ENOG4105DUX Transporter HHJ35_RS01195 ENOG4105CJ3 phosphate transporter HHJ35_RS01200 ENOG4105CBX hi0933 family HHJ35_RS01205 ENOG4107UNS conserved inner membrane protein HHJ35_RS01210 ENOG4105D0S secretion protein (HlyD HHJ35_RS01215 ENOG4105CJ1 ABC, transporter HHJ35_RS01220 ENOG4105CMI transporter HHJ35_RS01225 ENOG4105D2N Aldolase HHJ35_RS01240 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ35_RS01245 ENOG41090UW PTS System HHJ35_RS01265 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HHJ35_RS01270 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HHJ35_RS01275 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ35_RS01280 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ35_RS01285 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HHJ35_RS01290 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HHJ35_RS01295 ENOG4105DSF transport protein HHJ35_RS01300 ENOG4105F9N Major Facilitator Superfamily HHJ35_RS01305 ENOG4108W1V Lipoprotein HHJ35_RS01310 ENOG4105EX9 Membrane HHJ35_RS01325 ENOG4107FS9 Membrane HHJ35_RS01335 ENOG4105MG3 Membrane HHJ35_RS01340 ENOG4106H78 methyltransferase HHJ35_RS01345 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HHJ35_RS01350 ENOG4105CAK Cell division ATP-binding protein ftsE HHJ35_RS01355 ENOG4105CRP Part of the ABC transporter FtsEX involved in HHJ35_RS01360 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ35_RS01365 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HHJ35_RS01370 ENOG4108JQ1 Dehydrogenase HHJ35_RS01395 ENOG4105CP9 extracellular ligand-binding receptor HHJ35_RS01400 ENOG4105U59 -acetyltransferase HHJ35_RS01405 ENOG4105CP9 extracellular ligand-binding receptor HHJ35_RS01410 ENOG4105C32 Amino acid ABC transporter (Permease) HHJ35_RS01415 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HHJ35_RS01420 ENOG4105C0Z ABC transporter HHJ35_RS01425 ENOG4108IV0 ABC, transporter HHJ35_RS01430 ENOG4105BZ7 extracellular solute-binding protein family 1 HHJ35_RS01450 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HHJ35_RS01455 ENOG4105WC8 Conserved Protein HHJ35_RS01460 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HHJ35_RS01465 ENOG4106FA4 HHJ35_RS01485 ENOG4105WCN acetyltransferase HHJ35_RS01490 ENOG4105D9R oxidoreductase HHJ35_RS01495 ENOG4105C2I pirin domain protein HHJ35_RS01500 ENOG4105DIQ Transcriptional regulator HHJ35_RS01505 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HHJ35_RS01510 ENOG4105C6Z Gluconate HHJ35_RS01515 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HHJ35_RS01520 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ35_RS01545 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ35_RS01555 ENOG4108NAE Fimbrial chaperone protein HHJ35_RS01560 ENOG4105CW0 outer membrane usher protein HHJ35_RS01570 ENOG4108RQP Major type 1 subunit fimbrin HHJ35_RS01575 ENOG4108AF8 Chaperone HHJ35_RS01580 ENOG4105MHR Fimbrial protein HHJ35_RS01600 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HHJ35_RS01615 ENOG4105E98 transcriptional regulator DeoR family HHJ35_RS01620 ENOG4105CYB regulatoR HHJ35_RS01625 ENOG4105E0Y RtcB Protein HHJ35_RS01640 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ35_RS01645 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HHJ35_RS01650 ENOG4105C6Z Gluconate HHJ35_RS01660 ENOG4105MJ2 Competence protein HHJ35_RS01670 ENOG4105DNE Transposase HHJ35_RS01680 ENOG4105CE1 Ferrous iron transport protein b HHJ35_RS01685 ENOG4105XFK Ferrous iron transport protein A HHJ35_RS01690 ENOG4105BZM domain protein HHJ35_RS01695 ENOG4108RRZ Transcription elongation factor GreB HHJ35_RS01705 ENOG4105E0F Histidine kinase HHJ35_RS01715 ENOG4108MAJ Membrane HHJ35_RS01725 ENOG4105VEJ Heat shock protein HHJ35_RS01730 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HHJ35_RS01735 ENOG4105DQY intracellular growth attenuator HHJ35_RS01740 ENOG4107RK2 ADP-ribose diphosphatase NudE HHJ35_RS01745 ENOG4108JQC penicillin-binding protein 1A HHJ35_RS01750 ENOG4108U1Q Pilus assembly protein HHJ35_RS01755 ENOG41065NF Fimbrial assembly family protein HHJ35_RS01760 ENOG4105XPX DNA utilization protein HofO HHJ35_RS01765 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HHJ35_RS01770 ENOG4105E4G Type IV pilus HHJ35_RS01785 ENOG4105EGB membrane protein DamX HHJ35_RS01790 ENOG4105DFE Dna adenine methylase HHJ35_RS01795 ENOG4105DJV ribulose-phosphate 3-epimerase HHJ35_RS01800 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HHJ35_RS01805 ENOG4105C31 Tryptophanyl-tRNA synthetase HHJ35_RS01810 ENOG4108M21 HHJ35_RS01815 ENOG4105RMW regulation of transcription, DNA-dependent HHJ35_RS01820 ENOG4108626 Racemase HHJ35_RS01825 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HHJ35_RS01830 ENOG41080QX K07048 phosphotriesterase-related protein HHJ35_RS01835 ENOG4105MUZ Protein of unknown function DUF2620 HHJ35_RS01840 ENOG4106M0N transport system permease protein HHJ35_RS01845 ENOG4106PKC pyridoxal phosphate binding HHJ35_RS01850 ENOG4105VYH HHJ35_RS01860 ENOG4107V9H nitrite transporter HHJ35_RS01865 ENOG4105WZK nitrite reductase NADPH small subunit HHJ35_RS01870 ENOG4107QZF nitrite reductase NADPH large subunit HHJ35_RS01880 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ35_RS01890 ENOG4105MZU cell filamentation protein HHJ35_RS01895 ENOG4105DDQ anthranilate synthase HHJ35_RS01900 ENOG4105C8Y Acetylornithine aminotransferase HHJ35_RS01905 ENOG410613R integral membrane protein, YccS YhfK family HHJ35_RS01915 ENOG4108UKZ OsmC family HHJ35_RS01920 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HHJ35_RS01930 ENOG4105DNZ Alpha Beta Hydrolase HHJ35_RS01935 ENOG4105C5H ABC transporter HHJ35_RS01950 ENOG4105VKU nucleicacid-binding protein HHJ35_RS01955 ENOG4108YZY peptidylprolyl cis-trans isomerase HHJ35_RS01965 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ35_RS01970 ENOG4105WWK YheO domain protein HHJ35_RS02010 ENOG4108NNZ chitinase HHJ35_RS02015 ENOG4105W53 bacterioferritin-associated ferredoxin HHJ35_RS02020 ENOG4108UQY Iron-storage protein HHJ35_RS02025 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) HHJ35_RS02035 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) HHJ35_RS02040 ENOG4105R04 type II secretion system protein K HHJ35_RS02055 ENOG41069X0 general secretion pathway protein h HHJ35_RS02060 ENOG4108VAU general secretion pathway protein G HHJ35_RS02065 ENOG4105D7Q type ii secretion system HHJ35_RS02070 ENOG4107QHF type ii secretion system protein e HHJ35_RS02075 ENOG4105GVR general secretion pathway protein D HHJ35_RS02080 ENOG4107KSE General secretion pathway protein C HHJ35_RS02085 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression HHJ35_RS02090 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication HHJ35_RS02110 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HHJ35_RS02200 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HHJ35_RS02205 ENOG41067V7 50S ribosomal protein L36 HHJ35_RS02235 ENOG4105VTS DnaJ-like, subfamily C HHJ35_RS02240 ENOG4105W1Y Transcriptional regulator HHJ35_RS02245 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HHJ35_RS02255 ENOG4105C1A potassium transporter peripheral membrane HHJ35_RS02275 ENOG4105C79 DNA protecting protein DprA HHJ35_RS02285 ENOG4108WI1 Dna topoisomerase HHJ35_RS02300 ENOG4105SG3 Protein of unknown function (DUF1488) HHJ35_RS02305 ENOG4108Z0R Transferase HHJ35_RS02345 ENOG4105CDA abc transporter atp-binding protein HHJ35_RS02350 ENOG4105DRP amino acid AbC transporter HHJ35_RS02355 ENOG4105EZ7 amino acid ABC transporter HHJ35_RS02365 ENOG4105XCM membrane LIPOPROTEIN HHJ35_RS02370 ENOG4105BZS acriflavin resistance protein HHJ35_RS02375 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ35_RS02380 ENOG4108XG4 DNA-binding transcriptional regulator HHJ35_RS02385 ENOG41061ME transport protein HHJ35_RS02390 ENOG4105CEC DNA methylase N-4 N-6 HHJ35_RS02400 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ35_RS02410 ENOG4108IA2 Sodium pantothenate symporter HHJ35_RS02415 ENOG4105RG0 Membrane HHJ35_RS02420 ENOG4107UEK pfkb domain protein HHJ35_RS02425 ENOG4105E98 transcriptional regulator DeoR family HHJ35_RS02430 ENOG4105D2N Aldolase HHJ35_RS02435 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ35_RS02440 ENOG4105C2J ABC transporter HHJ35_RS02445 ENOG4105CNN ABC, transporter HHJ35_RS02450 ENOG4107UEK pfkb domain protein HHJ35_RS02460 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HHJ35_RS02465 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HHJ35_RS02475 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HHJ35_RS02480 ENOG41062P1 Diguanylate cyclase phosphodiesterase HHJ35_RS02490 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HHJ35_RS02495 ENOG4105VQ7 Rod shape-determining protein MreD HHJ35_RS02500 ENOG4108Z03 MAF-like protein HHJ35_RS02505 ENOG4105C03 ribonuclease HHJ35_RS02510 ENOG4105QD6 exported protein HHJ35_RS02515 ENOG4105D1U peptidase U62 modulator of DNA gyrase HHJ35_RS02520 ENOG4105CR8 Transcriptional regulator HHJ35_RS02525 ENOG4105ZQC membrane protein AaeX HHJ35_RS02540 ENOG4105UNR (Barnase) inhibitor HHJ35_RS02545 ENOG4105RID UPF0379 protein yhcN HHJ35_RS02560 ENOG4105C0H protease HHJ35_RS02565 ENOG4105C0H protease HHJ35_RS02570 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HHJ35_RS02575 ENOG4105D6Z AFG1 family ATPase HHJ35_RS02590 ENOG4107MKT Stringent starvation protein a HHJ35_RS02595 ENOG4105KB2 stringent starvation protein b HHJ35_RS02625 ENOG4108R66 Conserved Protein HHJ35_RS02630 ENOG4105BZ8 glutamate synthase HHJ35_RS02635 ENOG4105CBC glutamate synthase HHJ35_RS02640 ENOG4105N5T Radical SAM Protein HHJ35_RS02645 ENOG4105BZU Histidine kinase HHJ35_RS02650 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HHJ35_RS02660 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HHJ35_RS02665 ENOG41080Z8 PHOSPHOCARRIER protein HHJ35_RS02675 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HHJ35_RS02680 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HHJ35_RS02685 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ35_RS02690 ENOG4108IUZ ABC transporter HHJ35_RS02695 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HHJ35_RS02700 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HHJ35_RS02710 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ35_RS02715 ENOG4105FEU K -dependent Na -Ca exchanger HHJ35_RS02720 ENOG4105DHJ ABC, transporter HHJ35_RS02725 ENOG4105CY3 ABC transporter, permease HHJ35_RS02730 ENOG4107PE3 Mammalian cell entry related domain protein HHJ35_RS02735 ENOG4105E3I toluene tolerance HHJ35_RS02740 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HHJ35_RS02745 ENOG4105VFK BolA family HHJ35_RS02755 ENOG4105HVQ Regulatory factor of maltose metabolism HHJ35_RS02760 ENOG4105EAH synthase HHJ35_RS02775 ENOG4105QYV Membrane HHJ35_RS02785 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HHJ35_RS02790 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HHJ35_RS02795 ENOG4105HBR Rna-binding protein HHJ35_RS02805 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HHJ35_RS02810 ENOG4105EEI dihydropteroate synthase HHJ35_RS02820 ENOG4105NTZ Preprotein translocase subunit SecG HHJ35_RS02830 ENOG4105DIJ Phosphoethanolamine transferase HHJ35_RS02850 ENOG4105CHV Transcription elongation factor NusA HHJ35_RS02890 ENOG4105C1J atp-dependent rna helicase HHJ35_RS02895 ENOG4105CIC tryptophan-specific transport protein HHJ35_RS02900 ENOG4105DEN Luciferase family HHJ35_RS02920 ENOG4108YYD acetyltransferase HHJ35_RS02935 ENOG4107R7Y intracellular protease Pfpi family HHJ35_RS02940 ENOG4105K4T epimerase HHJ35_RS02945 ENOG4107S21 permease HHJ35_RS02950 ENOG4105W4M Transport-associated protein HHJ35_RS02965 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) HHJ35_RS02970 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HHJ35_RS02975 ENOG4106HBN Galactosamine-6-phosphate isomerase HHJ35_RS02980 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ35_RS02985 ENOG4105ETZ PTS System HHJ35_RS02990 ENOG4108UZY PTS System HHJ35_RS03000 ENOG4105E70 isomerase HHJ35_RS03005 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ35_RS03010 ENOG4108YTN IIa component HHJ35_RS03015 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ35_RS03025 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HHJ35_RS03035 ENOG4105E98 transcriptional regulator DeoR family HHJ35_RS03040 ENOG4105CTX dehydratase HHJ35_RS03045 ENOG4105DJB Major Facilitator Superfamily HHJ35_RS03055 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ35_RS03060 ENOG4105BZW Glycerate kinase HHJ35_RS03075 ENOG410811B TRANSCRIPTIONal HHJ35_RS03080 ENOG4105C7B Threonine dehydratase HHJ35_RS03095 ENOG4105C6N Formate acetyltransferase HHJ35_RS03100 ENOG4105KME endoribonuclease L-psp HHJ35_RS03105 ENOG4105EJQ L-serine dehydratase HHJ35_RS03110 ENOG4105C44 Serine transporter HHJ35_RS03120 ENOG4106D80 Uncharacterized protein YhaL HHJ35_RS03125 ENOG4108CNN domain protein HHJ35_RS03130 ENOG4105CWB LysR family transcriptional Regulator HHJ35_RS03135 ENOG4105KAF membrAne HHJ35_RS03140 ENOG4105CHF Glutathione S-transferase HHJ35_RS03145 ENOG4108VBZ doxx family HHJ35_RS03150 ENOG4105YJD HHJ35_RS03155 ENOG41090KG Inner membrane protein YqjE HHJ35_RS03160 ENOG4105NE1 Conserved Protein HHJ35_RS03165 ENOG4105WAY exported protein HHJ35_RS03170 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HHJ35_RS03175 ENOG4106W5V Membrane HHJ35_RS03180 ENOG4107YCY Transcriptional regulator HHJ35_RS03185 ENOG4105DPW Major facilitator superfamily MFS_1 HHJ35_RS03195 ENOG4105CTX dehydratase HHJ35_RS03200 ENOG4105P66 Membrane HHJ35_RS03210 ENOG4105DU1 integral membrane protein, terc HHJ35_RS03215 ENOG4105EE0 oxidoreductase HHJ35_RS03220 ENOG4108UB4 uncharacterized protein ygjQ HHJ35_RS03225 ENOG4108VKG metal-dependent hydrolase HHJ35_RS03235 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ35_RS03240 ENOG4107WCA isomerase HHJ35_RS03245 ENOG4107W6W Conserved Protein HHJ35_RS03250 ENOG4105E5D amino acid HHJ35_RS03255 ENOG4105FK9 beta-D-galactosidase beta subunit HHJ35_RS03260 ENOG4105CNT hydrolase family 2 HHJ35_RS03265 ENOG4105CQ4 Transcriptional regulator HHJ35_RS03270 ENOG4108Y51 tRNA-binding protein HHJ35_RS03280 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HHJ35_RS03285 ENOG4105NTW Transcriptional regulator HHJ35_RS03290 ENOG4105Q26 Siderophore-interacting protein HHJ35_RS03305 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ35_RS03310 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HHJ35_RS03330 ENOG4107GFK fumarate HHJ35_RS03350 ENOG4107ZVW dihydroneopterin aldolase HHJ35_RS03365 ENOG4106MWK domain protein HHJ35_RS03370 ENOG4105I7R Adenylate cyclase HHJ35_RS03390 ENOG4107S78 Band 7 protein HHJ35_RS03395 ENOG4105PV3 Inner membrane protein yqiJ HHJ35_RS03405 ENOG4105W0Z cytoplasmic protein HHJ35_RS03415 ENOG4108MY7 Fimbrial HHJ35_RS03420 ENOG4108TTM chaperone HHJ35_RS03430 ENOG4105H8W Fimbrial protein HHJ35_RS03445 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HHJ35_RS03455 ENOG4108N92 Thiol disulfide Interchange Protein HHJ35_RS03460 ENOG4108MR7 Arylsulfotransferase HHJ35_RS03465 ENOG4106032 Glutathionylspermidine synthase HHJ35_RS03475 ENOG4105DFG type I secretion outer membrane protein HHJ35_RS03480 ENOG41087AY ADP-Ribose pyrophosphatase HHJ35_RS03485 ENOG4108SX3 cytoplasmic protein HHJ35_RS03490 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HHJ35_RS03495 ENOG4105IPS esterase HHJ35_RS03500 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ35_RS03510 ENOG4105E0A ABC, transporter HHJ35_RS03515 ENOG4105DQ5 transport system permease protein HHJ35_RS03520 ENOG4105EHG Permease protein HHJ35_RS03530 ENOG4106KNT transcriptional regulator HHJ35_RS03535 ENOG4105VRH Antibiotic biosynthesis monooxygenase HHJ35_RS03540 ENOG4105NF4 modulator of drug activity HHJ35_RS03550 ENOG4107DEU Inner membrane protein YgiZ HHJ35_RS03555 ENOG4105DHQ Histidine kinase HHJ35_RS03560 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ35_RS03565 ENOG4105H4F exported protein HHJ35_RS03570 ENOG4105F4I Transcriptional regulator HHJ35_RS03575 ENOG4108J59 Extracellular solute-binding protein, family 5 HHJ35_RS03580 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ35_RS03585 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HHJ35_RS03590 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HHJ35_RS03595 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ35_RS03605 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ35_RS03610 ENOG4105DG4 malate L-lactate dehydrogenase HHJ35_RS03615 ENOG4105CPQ Dehydrogenase HHJ35_RS03620 ENOG4105DEI Mannitol dehydrogenase HHJ35_RS03625 ENOG4107YCY Transcriptional regulator HHJ35_RS03630 ENOG4105CCT upf0313 protein HHJ35_RS03640 ENOG4105ZKC Conserved Protein HHJ35_RS03645 ENOG4105CV8 reductase HHJ35_RS03650 ENOG4108I6A alcohol dehydrogenase HHJ35_RS03655 ENOG4105CF7 AraC family transcriptional regulator HHJ35_RS03660 ENOG4108K81 inner membrane protein YghB HHJ35_RS03665 ENOG4105C28 cystathionine HHJ35_RS03670 ENOG4105CWK Biopolymer transport protein, ExbB HHJ35_RS03675 ENOG4108ZZF transport protein (ExbD) HHJ35_RS03680 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HHJ35_RS03690 ENOG4105CPC Aldo Keto reductase HHJ35_RS03700 ENOG410900S Protein of unknown function (DUF2623) HHJ35_RS03705 ENOG4105E3S small subunit HHJ35_RS03710 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ35_RS03715 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HHJ35_RS03720 ENOG4105DPX Hydrogenase, large subunit HHJ35_RS03725 ENOG4108USZ hydrogenase HHJ35_RS03730 ENOG4108WGS hydrogenase 2-specific chaperone HHJ35_RS03735 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HHJ35_RS03740 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HHJ35_RS03745 ENOG4105CYM Glutathione S-transferase HHJ35_RS03750 ENOG4106032 Glutathionylspermidine synthase HHJ35_RS03755 ENOG4105CJ3 phosphate transporter HHJ35_RS03760 ENOG4108GH0 ATP-binding protein yghT HHJ35_RS03765 ENOG4108NDC ATP-binding protein yghS HHJ35_RS03770 ENOG4106FPV ATP-binding protein YghR HHJ35_RS03775 ENOG4108S55 polysaccharide biosynthesis protein HHJ35_RS03785 ENOG4108UUE Transcriptional regulator HHJ35_RS03790 ENOG4108M8S permease YjgP YjgQ family protein HHJ35_RS03800 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ35_RS03805 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ35_RS03815 ENOG4107RCI amp-dependent synthetase and ligase HHJ35_RS03825 ENOG4108KWP DNA-binding transcriptional regulator GlcC HHJ35_RS03830 ENOG4105CQB FAD linked oxidase domain protein HHJ35_RS03835 ENOG4105EU8 FAD linked oxidase domain protein HHJ35_RS03840 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ35_RS03845 ENOG4108ZJF Glcg protein HHJ35_RS03850 ENOG4107QP3 malate synthase g HHJ35_RS03855 ENOG4105DAA L-lactate HHJ35_RS03860 ENOG4105F88 accessory colonization factor AcfD HHJ35_RS03870 ENOG410765S (LipO)protein HHJ35_RS03875 ENOG4108XKW General secretion pathway protein C HHJ35_RS03885 ENOG4107QHF type ii secretion system protein e HHJ35_RS03890 ENOG4105D7Q type ii secretion system HHJ35_RS03895 ENOG4108VAU general secretion pathway protein G HHJ35_RS03905 ENOG4105X5Z General secretion pathway protein I HHJ35_RS03925 ENOG4105U1E general secretion pathway protein M HHJ35_RS03930 ENOG41090SZ ABC-2 type transporter HHJ35_RS03945 ENOG4105D2T synthase HHJ35_RS03970 ENOG41084CK capsule polysaccharide HHJ35_RS03975 ENOG4105E12 capsule polysaccharide HHJ35_RS03980 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) HHJ35_RS03985 ENOG4107V1M polysaccharide export protein HHJ35_RS03990 ENOG4105ECX polysaccharide export HHJ35_RS03995 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ35_RS04005 ENOG4105BZU Histidine kinase HHJ35_RS04030 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ35_RS04040 ENOG4108YGG dna repair protein HHJ35_RS04045 ENOG4105MFG Antirestriction protein HHJ35_RS04050 ENOG4106H6R UPF0380 protein HHJ35_RS04065 ENOG4108KZE transcriptional regulator HHJ35_RS04070 ENOG4105TS0 gtp-binding protein HHJ35_RS04095 ENOG4105D05 Receptor HHJ35_RS04120 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HHJ35_RS04150 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta HHJ35_RS04160 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC HHJ35_RS04165 ENOG4105CXY transporter HHJ35_RS04210 ENOG4108ZJG MrfB protein HHJ35_RS04215 ENOG4106PG1 outer membrane usher protein HHJ35_RS04220 ENOG4106P2F Pfam:Pili_assembly_C HHJ35_RS04230 ENOG4106CXJ Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 sp P42190 PAPK_ECOLI PROTEIN PAPK PRECURSOR HHJ35_RS04250 ENOG4105T40 surface antigen msp4 family protein HHJ35_RS04255 ENOG4108I6E Sulfatase HHJ35_RS04275 ENOG4108UQV Membrane HHJ35_RS04280 ENOG4105CXN decarboxylase HHJ35_RS04285 ENOG4105EAA nucleoside HHJ35_RS04300 ENOG4105CEN a g-specific adenine glycosylase HHJ35_RS04310 ENOG41090ED Protein with unknown function (DUF469) HHJ35_RS04315 ENOG4105K33 Periplasmic Protein HHJ35_RS04320 ENOG4105HDK L-asparaginase HHJ35_RS04325 ENOG4106MH3 alpha helix chain HHJ35_RS04330 ENOG4105CSA Coproporphyrinogen iii oxidase HHJ35_RS04335 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ35_RS04345 ENOG4108VIA integral membrane protein HHJ35_RS04350 ENOG4105DFA alanine racemase domain protein HHJ35_RS04355 ENOG4105CZX twitching motility protein HHJ35_RS04370 ENOG4105D7Z glutathione synthase HHJ35_RS04375 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HHJ35_RS04380 ENOG4105RWS endonuclease I HHJ35_RS04390 ENOG4107QNK )-transporter HHJ35_RS04410 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HHJ35_RS04425 ENOG4108K0D peptidase, M48 HHJ35_RS04430 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ35_RS04435 ENOG4105EPW hflc protein HHJ35_RS04440 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HHJ35_RS04445 ENOG4105CTS PTS system mannitol-specific HHJ35_RS04450 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HHJ35_RS04460 ENOG4108R4K DNA-binding, transcriptional regulator HHJ35_RS04465 ENOG4107Z1W Fructose transport system kinase HHJ35_RS04470 ENOG4108JJB ABC transporter HHJ35_RS04505 ENOG4105D2N Aldolase HHJ35_RS04510 ENOG4105D64 Mechanosensitive ion channel HHJ35_RS04515 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HHJ35_RS04520 ENOG4105MPN Membrane HHJ35_RS04525 ENOG4105DEQ transcriptional regulator HHJ35_RS04530 ENOG4105D5P Methylmalonyl-coA mutase HHJ35_RS04550 ENOG4108JQ1 Dehydrogenase HHJ35_RS04560 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HHJ35_RS04580 ENOG4107RAQ aminopeptidase HHJ35_RS04585 ENOG4105D0A hydroxylase HHJ35_RS04590 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ35_RS04615 ENOG4105CS2 ec 3.2.1.21 HHJ35_RS04625 ENOG4108UT2 hemolysin iii HHJ35_RS04635 ENOG4105Y75 tpr repeat protein HHJ35_RS04640 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HHJ35_RS04645 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HHJ35_RS04650 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HHJ35_RS04655 ENOG4105T95 Thiol disulfide interChange protein HHJ35_RS04660 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HHJ35_RS04670 ENOG4105CRK lysyL-tRNA synthetase HHJ35_RS04690 ENOG4105C2W permease HHJ35_RS04695 ENOG4105BZ8 glutamate synthase HHJ35_RS04700 ENOG4108R8B oxidoreductase Fe-S subunit HHJ35_RS04705 ENOG4105C7N Xanthine uracil vitamin C permease HHJ35_RS04710 ENOG4107QUY Guanine deaminase HHJ35_RS04715 ENOG4105C2W permease HHJ35_RS04720 ENOG4105C7W Xanthine dehydrogenase HHJ35_RS04725 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HHJ35_RS04730 ENOG4107UUR Chlorohydrolase aminohydrolase HHJ35_RS04735 ENOG4105BZ8 glutamate synthase HHJ35_RS04740 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HHJ35_RS04745 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HHJ35_RS04750 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HHJ35_RS04755 ENOG4105C5B carbamate kinase HHJ35_RS04765 ENOG4107S4Y M20 DapE family protein YgeY HHJ35_RS04770 ENOG4107RCH Diaminopropionate ammonia-lyase HHJ35_RS04775 ENOG4105IW6 Carbamoyltransferase HHJ35_RS04780 ENOG4108JUB Transcriptional regulator HHJ35_RS04785 ENOG4108UTP (2Fe-2S)-binding domain protein HHJ35_RS04790 ENOG4108HR6 Dehydrogenase HHJ35_RS04795 ENOG4105C7W Xanthine dehydrogenase HHJ35_RS04800 ENOG4108K5P (LipO)protein HHJ35_RS04810 ENOG4108MHD transport protein HHJ35_RS04815 ENOG4105CHU acetyl-coa acetyltransferase HHJ35_RS04825 ENOG4105CHR reductase HHJ35_RS04830 ENOG4107QNK )-transporter HHJ35_RS04840 ENOG4105RQF LysR family Transcriptional regulator HHJ35_RS04850 ENOG41060NJ transcriptional regulator HHJ35_RS04865 ENOG4105CPC Aldo Keto reductase HHJ35_RS04870 ENOG4105SUV lipoprotein YgdR HHJ35_RS04875 ENOG4105EE5 Membrane protein terC HHJ35_RS04890 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HHJ35_RS04905 ENOG4105IPU prepilin peptidase dependent protein A HHJ35_RS04910 ENOG4105JCS prepilin peptidase dependent protein HHJ35_RS04915 ENOG4105SEN Protein of unknown function (DUF2509) HHJ35_RS04920 ENOG4105RVB Prepilin peptidase dependent protein c HHJ35_RS04925 ENOG4105DSY exodeoxyribonuclease V, gamma HHJ35_RS04930 ENOG4107QXK peptidase HHJ35_RS04935 ENOG4107QKA exodeoxyribonuclease V beta HHJ35_RS04940 ENOG4107QYX exodeoxyribonuclease v alpha HHJ35_RS04945 ENOG4108EKC n-acetylglutamate synthase HHJ35_RS04950 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ35_RS04955 ENOG4105CID antiterminator HHJ35_RS04960 ENOG4105CI1 PTS System HHJ35_RS04965 ENOG4105C87 Aminotransferase class I and II HHJ35_RS04970 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ35_RS05060 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ35_RS05110 ENOG4105CA3 membrane-bound lytic murein transglycosylase HHJ35_RS05115 ENOG4105CUZ uba thif-type nad fad binding protein HHJ35_RS05120 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HHJ35_RS05125 ENOG4105C9B Cysteine desulfurase HHJ35_RS05130 ENOG4105M5B (LipO)protein HHJ35_RS05135 ENOG4105ETT transcriptional Regulator, LysR family HHJ35_RS05140 ENOG4105M08 Membrane HHJ35_RS05150 ENOG4107EDW L-fucose operon activator HHJ35_RS05160 ENOG4105CMG Carbohydrate kinase HHJ35_RS05170 ENOG4105EDR glucose galactose transporter HHJ35_RS05175 ENOG4107W7X Aldolase HHJ35_RS05180 ENOG4105C0A alcohol dehydrogenase HHJ35_RS05190 ENOG4105EJQ L-serine dehydratase HHJ35_RS05195 ENOG4105C44 Serine transporter HHJ35_RS05200 ENOG4105EWT decarboxylase family HHJ35_RS05215 ENOG4105WP7 tRNA pseudouridine synthase C HHJ35_RS05220 ENOG4105DR9 pseudouridine synthase HHJ35_RS05225 ENOG4105QDK Flavodoxin HHJ35_RS05230 ENOG4105DJB Major Facilitator Superfamily HHJ35_RS05235 ENOG4105EQX glucarate dehydratase HHJ35_RS05240 ENOG4105EQX glucarate dehydratase HHJ35_RS05245 ENOG4105BZU Histidine kinase HHJ35_RS05255 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ35_RS05260 ENOG4106A2Z transcriptional regulator antitoxin, MazE HHJ35_RS05265 ENOG4105MZG transcriptional modulator of maze toxin, mazf HHJ35_RS05270 ENOG4105DXN mazG family HHJ35_RS05285 ENOG4105HA9 of methanol dehydrogenase type HHJ35_RS05295 ENOG4105HA9 of methanol dehydrogenase type HHJ35_RS05305 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HHJ35_RS05315 ENOG4108ITV Inner membrane protein yqcE HHJ35_RS05320 ENOG4105CHR reductase HHJ35_RS05325 ENOG4107R3A FAD linked oxidase domain protein HHJ35_RS05330 ENOG4105C54 Major Facilitator superfamily HHJ35_RS05335 ENOG4106IKH Electron transfer flavoprotein HHJ35_RS05340 ENOG4105YBM electron transfer flavoprotein subunit ygcQ HHJ35_RS05345 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator HHJ35_RS05350 ENOG4105WQV ferredoxin-like protein HHJ35_RS05355 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ35_RS05360 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HHJ35_RS05380 ENOG4107635 Hok Gef family protein HHJ35_RS05385 ENOG4108MXK alkaline phosphatase isozyme conversion HHJ35_RS05405 ENOG4105N0Z inner membrane protein ygbE HHJ35_RS05440 ENOG4108K5P (LipO)protein HHJ35_RS05445 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ35_RS05460 ENOG4105C6Z Gluconate HHJ35_RS05465 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ35_RS05475 ENOG4105G63 Type III effector Hrp-dependent HHJ35_RS05485 ENOG4105MVE transcriptional regulator HHJ35_RS05490 ENOG4105MEW serine threonine protein phosphatase HHJ35_RS05500 ENOG4105VXR cytoplasmic protein HHJ35_RS05510 ENOG4108JUA Transcriptional regulator HHJ35_RS05515 ENOG4105C45 hydrogenase expression formation protein (HypE) HHJ35_RS05520 ENOG4105CQS hydrogenase expression formation protein HypD HHJ35_RS05525 ENOG41083WG hydrogenase assembly chaperone HHJ35_RS05530 ENOG4107RSS Hydrogenase accessory protein HypB HHJ35_RS05535 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HHJ35_RS05540 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HHJ35_RS05545 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HHJ35_RS05550 ENOG4107R30 NADH dehydrogenase HHJ35_RS05555 ENOG4107TDF Formate hydrogenlyase subunit 4 HHJ35_RS05560 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HHJ35_RS05565 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HHJ35_RS05570 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HHJ35_RS05575 ENOG4105I6X formate hydrogenlyase maturation HHJ35_RS05580 ENOG4108MG9 hydrogenase 3 maturation protease HHJ35_RS05590 ENOG4108Z3N Transcriptional regulator HHJ35_RS05595 ENOG4105CS2 ec 3.2.1.21 HHJ35_RS05600 ENOG4105C5Y PTS System HHJ35_RS05605 ENOG4105DDV Transcriptional regulator (LacI family HHJ35_RS05610 ENOG4108RC0 Electron transport protein HHJ35_RS05615 ENOG4105C8H hydrogenase maturation protein Hypf HHJ35_RS05635 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ35_RS05640 ENOG410804X Transcriptional regulator HHJ35_RS05645 ENOG4105J92 DNA-binding transcriptional activator GutM HHJ35_RS05650 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HHJ35_RS05655 ENOG4105VI0 Pts system, glucitol sorbitol-specific HHJ35_RS05660 ENOG4105DZY Pts system, glucitol sorbitol-specific HHJ35_RS05665 ENOG410787A Pts system, glucitol sorbitol-specific HHJ35_RS05670 ENOG4105CVE Lytic murein transglycosylase HHJ35_RS05675 ENOG4107TH8 cina domain protein HHJ35_RS05695 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HHJ35_RS05725 ENOG4107VXZ Hydrolase HHJ35_RS05730 ENOG4105W39 Membrane HHJ35_RS05755 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ35_RS05760 ENOG4105CW7 secretion protein, HlyD family HHJ35_RS05765 ENOG4105NTK Transcriptional repressor Mpra HHJ35_RS05770 ENOG4105ZED uncharacterized protein ygaH HHJ35_RS05775 ENOG4108UMN azlc family HHJ35_RS05780 ENOG4105EQ0 Major Facilitator superfamily HHJ35_RS05785 ENOG4105GIJ Glycine betaine HHJ35_RS05790 ENOG4108HQS Glycine betaine HHJ35_RS05795 ENOG4108IJ7 Glycine betaine HHJ35_RS05800 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ35_RS05805 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ35_RS05815 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HHJ35_RS05820 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HHJ35_RS05830 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HHJ35_RS05835 ENOG4108WMJ Protein of unknown function (DUF2002) HHJ35_RS05840 ENOG4108RNS Exports L-alanine (By similarity) HHJ35_RS05845 ENOG4108X73 DNA- binding protein HHJ35_RS05850 ENOG4108V62 Rhodanese domain protein HHJ35_RS05855 ENOG41080HT Transcriptional regulator, arsr family HHJ35_RS05860 ENOG4105VPI YqaE family transport protein HHJ35_RS05865 ENOG4109066 lysm domain bon superfamily protein HHJ35_RS05870 ENOG4108PVQ transcriptional regulator HHJ35_RS05875 ENOG4105C85 amino acid HHJ35_RS05880 ENOG4108JPW Aminotransferase HHJ35_RS05885 ENOG4105C26 Dehydrogenase HHJ35_RS05890 ENOG4105D5U fad dependent oxidoreductase HHJ35_RS05915 ENOG4107R08 Integrase HHJ35_RS05930 ENOG4108R7K Metal Dependent Phosphohydrolase HHJ35_RS05935 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) HHJ35_RS05940 ENOG4105H40 HHJ35_RS05955 ENOG4105RDA repressor HHJ35_RS05960 ENOG41078CG DNA-binding transcriptional regulator HHJ35_RS05965 ENOG4108S1U HHJ35_RS05995 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HHJ35_RS06005 ENOG4108MXB Protein of unknown function (DUF968) HHJ35_RS06010 ENOG4105HGD Antitermination protein HHJ35_RS06030 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HHJ35_RS06055 ENOG4105CAR Terminase, large subunit HHJ35_RS06065 ENOG4105EFC phage portal protein HK97 family HHJ35_RS06110 ENOG4105TKZ Tail Sheath HHJ35_RS06130 ENOG4108NKR DNA circulation protein HHJ35_RS06150 ENOG4108T86 baseplate J family protein HHJ35_RS06155 ENOG4105Y0G tail protein HHJ35_RS06160 ENOG4105Y9F tail fiber protein HHJ35_RS06165 ENOG4108US3 tail fiber assembly HHJ35_RS06170 ENOG4105PTU response to oxidative stress HHJ35_RS06220 ENOG4108Z1B Cyclase dehydrase HHJ35_RS06230 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ35_RS06235 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HHJ35_RS06250 ENOG4108JU6 CBS domain protein HHJ35_RS06255 ENOG4106KVJ cytochrome C assembly protein HHJ35_RS06260 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HHJ35_RS06285 ENOG41090EK ompa motb domain protein HHJ35_RS06290 ENOG4108KHX Diguanylate cyclase HHJ35_RS06295 ENOG4108WS1 HHJ35_RS06300 ENOG4105QP9 Protein of unknown function (DUF2799) HHJ35_RS06305 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ35_RS06310 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HHJ35_RS06315 ENOG4105CQC Prephenate dehydratase HHJ35_RS06325 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HHJ35_RS06330 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HHJ35_RS06335 ENOG4105C34 Pseudouridine synthase HHJ35_RS06340 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HHJ35_RS06345 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ35_RS06380 ENOG4105CSH Transporter HHJ35_RS06385 ENOG4105T42 (LipO)protein HHJ35_RS06390 ENOG4105JIM Phosphatidylserine synthase HHJ35_RS06395 ENOG4105CD5 CoA-binding domain protein HHJ35_RS06400 ENOG4106IUH DTW domain containing protein HHJ35_RS06405 ENOG4105K63 Thioredoxin HHJ35_RS06410 ENOG4105EIB trna rrna methyltransferase HHJ35_RS06430 ENOG41090KR LysR family transcriptional Regulator HHJ35_RS06435 ENOG4105C1J atp-dependent rna helicase HHJ35_RS06445 ENOG4108IYU L-aspartate oxidase HHJ35_RS06455 ENOG4105EMN RNA polymerase sigma factor HHJ35_RS06460 ENOG41069PW sigma-e factor negative regulatory protein HHJ35_RS06465 ENOG4105VQK sigma E regulatory protein, MucB RseB HHJ35_RS06470 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HHJ35_RS06480 ENOG4105C3F Signal peptidase i HHJ35_RS06500 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HHJ35_RS06515 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HHJ35_RS06520 ENOG4106G6Q Transcriptional regulator HHJ35_RS06525 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HHJ35_RS06530 ENOG4108Z6B deaminase HHJ35_RS06545 ENOG4107WP9 Histidine kinase HHJ35_RS06550 ENOG4108SKK alpha helix protein HHJ35_RS06555 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ35_RS06565 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ35_RS06575 ENOG4108NZE NAGC-like transcriptional regulator HHJ35_RS06580 ENOG4107HQ7 repeat protein HHJ35_RS06585 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HHJ35_RS06590 ENOG4108F37 ATP-binding component of a transport system HHJ35_RS06595 ENOG4105CNN ABC, transporter HHJ35_RS06600 ENOG4105CPQ Dehydrogenase HHJ35_RS06605 ENOG4108ZKT aldose 1-epimerase HHJ35_RS06610 ENOG4108SB3 DoxX Family HHJ35_RS06615 ENOG4105D8G Major Facilitator superfamily HHJ35_RS06620 ENOG4108MN2 Stationary phase inducible protein CsiE HHJ35_RS06625 ENOG4107XM9 (LipO)protein HHJ35_RS06630 ENOG4105ECY inositol monophosphatase HHJ35_RS06650 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HHJ35_RS06670 ENOG4108ZIT Ferredoxin, 2FE-2S HHJ35_RS06675 ENOG4105WVQ Fe-S assembly protein IscX HHJ35_RS06685 ENOG4105YYA enhanced serine sensitivity protein SseB HHJ35_RS06690 ENOG4105KHC sulfurtransferase HHJ35_RS06695 ENOG4105DN3 alpha-2-macroglobulin domain protein HHJ35_RS06700 ENOG4108JQB penicillin-binding protein 1C HHJ35_RS06730 ENOG4105N21 Membrane HHJ35_RS06745 ENOG4105VPD cellular component movement HHJ35_RS06770 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HHJ35_RS06780 ENOG41066DY Membrane HHJ35_RS06785 ENOG4108ZMA Outer membrane lipoprotein HHJ35_RS06790 ENOG41062G3 Protein of unknown function (DUF2633) HHJ35_RS06800 ENOG4105BZU Histidine kinase HHJ35_RS06805 ENOG4105C9X ppx gppa phosphatase HHJ35_RS06810 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HHJ35_RS06815 ENOG4108V3E phosphoribosylglycinamide formyltransferase HHJ35_RS06830 ENOG4105C2W permease HHJ35_RS06835 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HHJ35_RS06840 ENOG4105K89 arsenate reductase HHJ35_RS06845 ENOG4105ERG peptidase m48, ste24p HHJ35_RS06850 ENOG4105C02 permease HHJ35_RS06855 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HHJ35_RS06860 ENOG4105RH4 Glycine cleavage system transcriptional repressor HHJ35_RS06870 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ35_RS06880 ENOG4105CGZ zinc metallopeptidase HHJ35_RS06890 ENOG4106KED esterase YpfH HHJ35_RS06905 ENOG4105KUZ arsenate reductase HHJ35_RS06915 ENOG4105BZS acriflavin resistance protein HHJ35_RS06920 ENOG4105BZU Histidine kinase HHJ35_RS06925 ENOG4105BZ8 glutamate synthase HHJ35_RS06935 ENOG4108PVD exported protein HHJ35_RS06940 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ35_RS06945 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ35_RS06950 ENOG4105C6K Malic enzyme HHJ35_RS06955 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HHJ35_RS06960 ENOG4106S4J ethanolamine utilization protein EutP HHJ35_RS06965 ENOG4105NDK ethanolamine utilization protein HHJ35_RS06970 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HHJ35_RS06975 ENOG4107WUY phosphate acetyltransferase HHJ35_RS06980 ENOG4105KNY Microcompartments protein HHJ35_RS06985 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HHJ35_RS06990 ENOG4108EKI Dehydrogenase HHJ35_RS06995 ENOG4107RWI ethanolamine utilization protein eutJ HHJ35_RS07000 ENOG4105C0A alcohol dehydrogenase HHJ35_RS07005 ENOG4105ENY Ethanolamine utilization protein eutH HHJ35_RS07010 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HHJ35_RS07025 ENOG4106D67 ethanolamine utilization protein HHJ35_RS07030 ENOG4108X49 Ethanolamine utilization protein EutK HHJ35_RS07035 ENOG4108K3Z AraC family transcriptional regulator HHJ35_RS07045 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HHJ35_RS07055 ENOG4105QZU Inner membrane protein YfeZ HHJ35_RS07060 ENOG4105E7K (LipO)protein HHJ35_RS07065 ENOG4105EZR dyp-type peroxidase family protein HHJ35_RS07080 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HHJ35_RS07085 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HHJ35_RS07090 ENOG4108I5D sulfate abc transporter HHJ35_RS07095 ENOG4105ECW sulfate abc transporter HHJ35_RS07100 ENOG4108IJ6 ABC transporter HHJ35_RS07105 ENOG4105C6T cysteine synthase HHJ35_RS07110 ENOG4105M0Y HHJ35_RS07120 ENOG4105C5Y PTS System HHJ35_RS07125 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ35_RS07135 ENOG4105C6T cysteine synthase HHJ35_RS07155 ENOG4105VRT cytoplasmic protein HHJ35_RS07160 ENOG4105DHU Bile acid HHJ35_RS07165 ENOG4108M0I Transcriptional regulator HHJ35_RS07170 ENOG4108NFH Sugar hydrolase HHJ35_RS07175 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HHJ35_RS07180 ENOG4105EAA nucleoside HHJ35_RS07190 ENOG4105CN8 Transcriptional regulator HHJ35_RS07220 ENOG4105GXM Putative transcription regulator (DUF1323) HHJ35_RS07225 ENOG4105HZG regulatoR HHJ35_RS07240 ENOG4108KMM Diguanylate cyclase HHJ35_RS07245 ENOG4105D9N nucleoside HHJ35_RS07255 ENOG4109076 Conserved Protein HHJ35_RS07270 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ35_RS07275 ENOG410863U PTS System HHJ35_RS07280 ENOG4105DC7 peptidase M24 HHJ35_RS07285 ENOG4105CN9 Peptidase m42 family protein HHJ35_RS07290 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ35_RS07295 ENOG4108CIP transcriptional regulator HHJ35_RS07300 ENOG4105DY9 regulatoR HHJ35_RS07305 ENOG4108HRK Histidine kinase HHJ35_RS07310 ENOG4105CHM Aminotransferase HHJ35_RS07320 ENOG4105D1S lipid A biosynthesis HHJ35_RS07325 ENOG4105W9M Membrane HHJ35_RS07335 ENOG4108V08 YfdX protein HHJ35_RS07345 ENOG4105CFN oxalyl-CoA decarboxylase HHJ35_RS07350 ENOG4108N2Y auxin Efflux HHJ35_RS07355 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HHJ35_RS07360 ENOG4105BZU Histidine kinase HHJ35_RS07365 ENOG4108WQH regulatoR HHJ35_RS07370 ENOG4105CW7 secretion protein, HlyD family HHJ35_RS07375 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ35_RS07390 ENOG4105W8I Transcriptional regulator HHJ35_RS07400 ENOG4105S64 Formate nitrite transporter HHJ35_RS07405 ENOG410903C (LipO)protein HHJ35_RS07410 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HHJ35_RS07415 ENOG4105KZW UPF0381 protein HHJ35_RS07430 ENOG4108BY2 phosphohistidine phosphatase HHJ35_RS07440 ENOG4106PG1 outer membrane usher protein HHJ35_RS07445 ENOG4108FZ9 Chaperone HHJ35_RS07450 ENOG4105NEV Fimbrial HHJ35_RS07455 ENOG4105UGQ Fimbrial HHJ35_RS07460 ENOG4105US4 fimbrial-like protein yfcP HHJ35_RS07490 ENOG4105EJ9 Membrane HHJ35_RS07495 ENOG4108BPE -transporting atpase HHJ35_RS07500 ENOG4105MH2 YfcL protein HHJ35_RS07510 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ35_RS07515 ENOG4105F9N Major Facilitator Superfamily HHJ35_RS07520 ENOG4106WZ1 flagella biosynthesis regulator HHJ35_RS07530 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ35_RS07540 ENOG4105DQR SNARE associated Golgi HHJ35_RS07550 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HHJ35_RS07555 ENOG4108S3P Sporulation domain protein HHJ35_RS07560 ENOG4105E96 Colicin v production protein HHJ35_RS07565 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HHJ35_RS07570 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HHJ35_RS07575 ENOG4105E89 ABC transporter HHJ35_RS07580 ENOG4105E89 ABC transporter HHJ35_RS07585 ENOG4105DSP amino acid AbC transporter HHJ35_RS07590 ENOG4106YG3 ABC transporter HHJ35_RS07595 ENOG4108JEH abc transporter atp-binding protein HHJ35_RS07600 ENOG4105DNE Transposase HHJ35_RS07605 ENOG4105ECP epimerase HHJ35_RS07610 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HHJ35_RS07615 ENOG4105CYM Glutathione S-transferase HHJ35_RS07620 ENOG4108SHQ Glutathione S-transferase HHJ35_RS07625 ENOG4108RE9 Phosphodiesterase HHJ35_RS07630 ENOG4105PTV Nudix Hydrolase HHJ35_RS07635 ENOG4105CSX c4-dicarboxylate anaerobic carrier HHJ35_RS07640 ENOG4105C6K Malic enzyme HHJ35_RS07645 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HHJ35_RS07655 ENOG4105XWI UPF0304 protein HHJ35_RS07660 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HHJ35_RS07665 ENOG4107QWE )-transporter HHJ35_RS07675 ENOG4105CHM Aminotransferase HHJ35_RS07680 ENOG4107NQ8 LysR family Transcriptional regulator HHJ35_RS07700 ENOG4105GKE subunit e HHJ35_RS07705 ENOG4107QIZ NADH dehydrogenase HHJ35_RS07710 ENOG4108IEH NADH dehydrogenase subunit g HHJ35_RS07725 ENOG4107UFS subunit j HHJ35_RS07735 ENOG4105D65 subunit l HHJ35_RS07740 ENOG4105C8S subunit m HHJ35_RS07750 ENOG4105GDX Domain of unknown function (DUF1877) HHJ35_RS07755 ENOG4107VAM peptidase, m28 HHJ35_RS07760 ENOG4105CP2 von willebrand factor, type a HHJ35_RS07770 ENOG4107YB6 acetyltransferase, (GNAT) family HHJ35_RS07775 ENOG4105TNS Conserved Protein HHJ35_RS07780 ENOG4105E4F Isochorismate synthase HHJ35_RS07795 ENOG4108IPT Naphthoate synthase HHJ35_RS07805 ENOG4105CEY Amp-dependent synthetase and ligase HHJ35_RS07810 ENOG4106GZG polymyxin resistance protein B HHJ35_RS07860 ENOG4108UII YfaZ family HHJ35_RS07865 ENOG4108EWA cinA-like protein HHJ35_RS07870 ENOG4107258 Transcriptional regulator HHJ35_RS07880 ENOG4105CSP Major Facilitator Superfamily HHJ35_RS07895 ENOG4105DNE Transposase HHJ35_RS07900 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ35_RS07910 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HHJ35_RS07915 ENOG4105CXY transporter HHJ35_RS07920 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HHJ35_RS07925 ENOG4105FQR PH-inducible protein involved in stress response HHJ35_RS07930 ENOG4105XPH Ferredoxin HHJ35_RS07935 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ35_RS07940 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ35_RS07945 ENOG4107GHC outer membrane autotransporter HHJ35_RS07955 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ35_RS07960 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HHJ35_RS07970 ENOG4107S52 alpha-2-macroglobulin domain protein HHJ35_RS07975 ENOG41081SK signal peptide protein HHJ35_RS07980 ENOG4105EDV vault protein HHJ35_RS07985 ENOG4105CHU acetyl-coa acetyltransferase HHJ35_RS07990 ENOG4105CRW Short chain fatty acid transporter HHJ35_RS07995 ENOG4107QNJ CoA-transferase subunit B HHJ35_RS08000 ENOG4107QP7 CoA-transferase subunit A HHJ35_RS08005 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ35_RS08010 ENOG4105BZU Histidine kinase HHJ35_RS08015 ENOG4105BZU Histidine kinase HHJ35_RS08020 ENOG41068CG regulatoR HHJ35_RS08025 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HHJ35_RS08030 ENOG4105FCK Membrane HHJ35_RS08035 ENOG4105CJ2 (LipO)protein HHJ35_RS08040 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ35_RS08045 ENOG4105CF1 Alkylated DNA repair protein HHJ35_RS08050 ENOG4105IBP Cyclic peptide transporter HHJ35_RS08065 ENOG4108ZNS ferredoxin-type protein NapF HHJ35_RS08070 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HHJ35_RS08080 ENOG4108BGM Quinol dehydrogenase periplasmic component HHJ35_RS08085 ENOG4105GXZ Ferredoxin-type protein NapH HHJ35_RS08090 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HHJ35_RS08095 ENOG4105CUW cytochrome C-TYPE protein HHJ35_RS08105 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HHJ35_RS08110 ENOG41060IM Heme exporter protein HHJ35_RS08115 ENOG4105X3C heme exporter protein HHJ35_RS08125 ENOG4105DA4 cytochrome c-type biogenesis protein HHJ35_RS08130 ENOG4107QX9 Thiol disulfide interChange protein HHJ35_RS08135 ENOG4105KWW Biogenesis protein HHJ35_RS08140 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ35_RS08145 ENOG4108MGN ATP-binding component of a transport system HHJ35_RS08150 ENOG4108MGN ATP-binding component of a transport system HHJ35_RS08160 ENOG4105E68 Sulfatase HHJ35_RS08180 ENOG4105CFI type iii restriction protein res subunit HHJ35_RS08185 ENOG4105I08 Pseudouridine synthase HHJ35_RS08190 ENOG4105C2C drug resistance transporter, Bcr CflA HHJ35_RS08195 ENOG4105HG6 HHJ35_RS08200 ENOG4108JQ5 ABC transporter HHJ35_RS08205 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HHJ35_RS08210 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HHJ35_RS08215 ENOG4105E43 Extracellular solute-binding protein, family 5 HHJ35_RS08220 ENOG4105CXC rtn protein HHJ35_RS08225 ENOG4107TT5 NLP P60 protein HHJ35_RS08230 ENOG41076MN Phosphoesterase, PA-phosphatase related HHJ35_RS08235 ENOG4105CKI cobalamin synthesis protein HHJ35_RS08240 ENOG4105DEI Mannitol dehydrogenase HHJ35_RS08250 ENOG4105KRS Proteinase inhibitor HHJ35_RS08255 ENOG4105S8Q sugar efflux transporter HHJ35_RS08260 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HHJ35_RS08265 ENOG4105DE4 1-phosphofructokinase HHJ35_RS08270 ENOG4105DM4 PTS System HHJ35_RS08275 ENOG4105DD7 kinase (PfkB family HHJ35_RS08280 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HHJ35_RS08285 ENOG4105D9N nucleoside HHJ35_RS08290 ENOG4108Y4K DNA-binding transcriptional activator HHJ35_RS08300 ENOG4105DD7 kinase (PfkB family HHJ35_RS08310 ENOG4105HMI Membrane HHJ35_RS08315 ENOG4105DUM transcriptional regulator, lysR family HHJ35_RS08320 ENOG4108IQI permease HHJ35_RS08325 ENOG4105D05 Receptor HHJ35_RS08340 ENOG4105DHF Membrane HHJ35_RS08345 ENOG41060NJ transcriptional regulator HHJ35_RS08350 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HHJ35_RS08355 ENOG4105C2J ABC transporter HHJ35_RS08360 ENOG4108HWV )-transporter HHJ35_RS08365 ENOG4107SJI Dehydrogenase HHJ35_RS08370 ENOG4105BZ8 glutamate synthase HHJ35_RS08375 ENOG4105Y9N Membrane HHJ35_RS08380 ENOG4107GZ4 SanA protein HHJ35_RS08390 ENOG41067MG lrgb family HHJ35_RS08400 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HHJ35_RS08410 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ35_RS08415 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HHJ35_RS08420 ENOG4105KHU inner membrane protein YohD HHJ35_RS08425 ENOG41069YE inner membrane protein yohC HHJ35_RS08430 ENOG41061WM D-Alanyl-D-Alanine HHJ35_RS08435 ENOG4105CXG d-lactate dehydrogenase HHJ35_RS08440 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HHJ35_RS08445 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HHJ35_RS08450 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HHJ35_RS08455 ENOG4108IJ8 ABC transporter HHJ35_RS08460 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HHJ35_RS08470 ENOG4108XDN Transcriptional regulator HHJ35_RS08475 ENOG4108HRK Histidine kinase HHJ35_RS08480 ENOG4108NEV two component transcriptional regulator, LytTR family HHJ35_RS08485 ENOG4108W15 Protein of unknown function (DUF1456) HHJ35_RS08490 ENOG4108YCW (LipO)protein HHJ35_RS08495 ENOG410903U zinc ion binding HHJ35_RS08500 ENOG4105DEG Vwa containing coxe family protein HHJ35_RS08505 ENOG4105RD5 HHJ35_RS08510 ENOG4105KKX ATPase associated with various cellular activities aaa_5 HHJ35_RS08520 ENOG4108KDT Molybdate metabolism regulator HHJ35_RS08525 ENOG4108KDT Molybdate metabolism regulator HHJ35_RS08535 ENOG4105D1F ATP-binding protein HHJ35_RS08540 ENOG41067AK Protein of unknown function (DUF2574) HHJ35_RS08545 ENOG41063W2 Fimbrial protein HHJ35_RS08550 ENOG4108MQF Chaperone HHJ35_RS08555 ENOG4105CW0 outer membrane usher protein HHJ35_RS08560 ENOG410662B Type-1 fimbrial protein HHJ35_RS08565 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HHJ35_RS08585 ENOG4105DWF phosphomethylpyrimidine kinase HHJ35_RS08590 ENOG4108UQ1 hydrolase, family 25 HHJ35_RS08595 ENOG4105FDP GntR family transcriptional regulator HHJ35_RS08600 ENOG4108TFM Kinase, PfkB family HHJ35_RS08605 ENOG4108KD5 ADP-ribosylation crystallin J1 HHJ35_RS08610 ENOG4105EAA nucleoside HHJ35_RS08615 ENOG4105EIE fructose-bisphosphate aldolase HHJ35_RS08630 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HHJ35_RS08635 ENOG41090UW PTS System HHJ35_RS08640 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ35_RS08645 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HHJ35_RS08660 ENOG41076Z6 Uncharacterized protein yegR HHJ35_RS08665 ENOG4105CFP Peptidase U32 HHJ35_RS08690 ENOG4105KWI UPF0339 protein HHJ35_RS08695 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ35_RS08700 ENOG4105EB3 Histidine kinase HHJ35_RS08735 ENOG4108M24 von Willebrand factor, type A HHJ35_RS08740 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HHJ35_RS08745 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding HHJ35_RS08750 ENOG4105R8A Heat shock protein HHJ35_RS08755 ENOG4105D03 DNA-3-methyladenine glycosylase II HHJ35_RS08760 ENOG4105BZU Histidine kinase HHJ35_RS08765 ENOG4105DBI uridine monophosphokinase HHJ35_RS08775 ENOG4108GAE asmA family HHJ35_RS08790 ENOG4105EE5 Membrane protein terC HHJ35_RS08800 ENOG4105DAY polysaccharide export protein HHJ35_RS08805 ENOG4105KJF protein tyrosine phosphatase HHJ35_RS08810 ENOG4105D75 Capsular exopolysaccharide family HHJ35_RS08815 ENOG41090RK glycosyl transferase HHJ35_RS08820 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HHJ35_RS08825 ENOG4107RXY Glycosyl transferase HHJ35_RS08830 ENOG4108NYJ Colanic acid HHJ35_RS08835 ENOG4105ECJ Glycosyl Transferase HHJ35_RS08840 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HHJ35_RS08845 ENOG4105C0K Gdp-mannose 4,6-dehydratase HHJ35_RS08850 ENOG4105C30 Nad-dependent epimerase dehydratase HHJ35_RS08855 ENOG4105FGF GDP-mannose mannosyl hydrolase HHJ35_RS08860 ENOG4106CD9 glycosyl transferase group 1 HHJ35_RS08865 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HHJ35_RS08870 ENOG4107QKV phosphomannomutase HHJ35_RS08875 ENOG4105D3Q Sugar transferase HHJ35_RS08880 ENOG4105PSV Polysaccharide Biosynthesis Protein HHJ35_RS08885 ENOG4105C74 pyruvyl transferase HHJ35_RS08890 ENOG4107T8Q Glycosyl transferase (Group 1 HHJ35_RS08895 ENOG4105G1A colanic acid biosynthesis protein HHJ35_RS08900 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ35_RS08905 ENOG4105C1B dTDP-glucose 4-6-dehydratase HHJ35_RS08910 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase HHJ35_RS08915 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HHJ35_RS08920 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase HHJ35_RS08930 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HHJ35_RS08945 ENOG4105K64 Glycosyl transferase, family 2 HHJ35_RS08955 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HHJ35_RS08960 ENOG4105C6Y Udp-glucose 6-dehydrogenase HHJ35_RS08965 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HHJ35_RS08970 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase HHJ35_RS08985 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HHJ35_RS08990 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HHJ35_RS09000 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) HHJ35_RS09015 ENOG4105VTW prevent-host-death family HHJ35_RS09020 ENOG4105KRQ Addiction module toxin, Txe YoeB family HHJ35_RS09025 ENOG4107SRH Nad-dependent epimerase dehydratase HHJ35_RS09030 ENOG4105EQ1 Transcriptional regulator HHJ35_RS09040 ENOG4105CUB amino acid HHJ35_RS09045 ENOG4105CJB Exodeoxyribonuclease I HHJ35_RS09050 ENOG4105DZ1 carboxypeptidase HHJ35_RS09060 ENOG4105DR8 Membrane HHJ35_RS09095 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ35_RS09105 ENOG4108YGG dna repair protein HHJ35_RS09110 ENOG4106549 Antirestriction protein HHJ35_RS09115 ENOG4106H6R UPF0380 protein HHJ35_RS09135 ENOG4108YIV HHJ35_RS09140 ENOG4108F5E vimentin HHJ35_RS09160 ENOG4105EHG Permease protein HHJ35_RS09165 ENOG4108F1U ABC transporter HHJ35_RS09215 ENOG410836F Transposase HHJ35_RS09250 ENOG41080QX K07048 phosphotriesterase-related protein HHJ35_RS09265 ENOG4108RVA ribokinase HHJ35_RS09280 ENOG4105SRB Uncharacterized protein yaiO HHJ35_RS09285 ENOG4107RMY Bacterial transferase hexapeptide repeat protein HHJ35_RS09290 ENOG4108PBI Polysaccharide metabolism HHJ35_RS09295 ENOG4107W19 lmbE family HHJ35_RS09300 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HHJ35_RS09305 ENOG4105GTN ParB Domain Protein Nuclease HHJ35_RS09315 ENOG4108YZT Adenosylcobinamide kinase HHJ35_RS09330 ENOG4108PXI ErfK YbiS YcfS YnhG HHJ35_RS09360 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ35_RS09375 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HHJ35_RS09380 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) HHJ35_RS09385 ENOG4105C1G acyl-Coa dehydrogenase HHJ35_RS09415 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) HHJ35_RS09440 ENOG4108VTW Thioesterase HHJ35_RS09460 ENOG4105UQX Mate efflux family protein HHJ35_RS09470 ENOG4107R11 Transcriptional regulator HHJ35_RS09475 ENOG4106P55 Transcriptional regulator HHJ35_RS09485 ENOG4105CDY transcriptional regulatory protein HHJ35_RS09490 ENOG4105FYV Amp nucleosidase HHJ35_RS09495 ENOG4105CSH Transporter HHJ35_RS09505 ENOG4105TNG K13735 adhesin invasin HHJ35_RS09510 ENOG4105TNG K13735 adhesin invasin HHJ35_RS09515 ENOG4105TNG K13735 adhesin invasin HHJ35_RS09520 ENOG4107ZSV Receptor HHJ35_RS09525 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HHJ35_RS09545 ENOG4105C0W non-ribosomal peptide synthetase HHJ35_RS09560 ENOG4105BZ1 (ABC) transporter HHJ35_RS09565 ENOG4105EYM Major Facilitator superfamily HHJ35_RS09625 ENOG4108YX2 DNA-binding protein HHJ35_RS09715 ENOG4105DFP Integrase HHJ35_RS09720 ENOG4108MEK Metal-binding protein YodA HHJ35_RS09725 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) HHJ35_RS09730 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) HHJ35_RS09735 ENOG4105VT2 5-hydroxyisourate hydrolase HHJ35_RS09740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ35_RS09745 ENOG4107ZY3 Histidine kinase HHJ35_RS09755 ENOG4105ZIT Porin Gram-negative type HHJ35_RS09760 ENOG4105Y0K Inner membrane protein YedR HHJ35_RS09765 ENOG4105EST Metal Dependent Phosphohydrolase HHJ35_RS09770 ENOG4105DVF Cytosine-specific methyltransferase HHJ35_RS09775 ENOG41090BB DNA mismatch endonuclease (vsr) HHJ35_RS09780 ENOG4105FDR Membrane HHJ35_RS09785 ENOG4105CKW Inner membrane protein yedI HHJ35_RS09790 ENOG4105VNZ cytoplasmic protein HHJ35_RS09795 ENOG4105BZU Histidine kinase HHJ35_RS09800 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase HHJ35_RS09805 ENOG4105YX3 cellular response to acidity HHJ35_RS09815 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HHJ35_RS09820 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HHJ35_RS09830 ENOG4105CN7 Flagellar biosynthetic protein FliP HHJ35_RS09835 ENOG4105K0P flagellar biosynthesis protein HHJ35_RS09840 ENOG4105DD5 Flagellar motor switch protein HHJ35_RS09845 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ35_RS09850 ENOG4107ZI8 flagellar basal body-associated protein flil HHJ35_RS09855 ENOG4105WF4 Flagellar hook-length control protein HHJ35_RS09860 ENOG4105GSA Flagellar export protein flij HHJ35_RS09865 ENOG4108JIR Flagellum-specific ATP synthase HHJ35_RS09870 ENOG41090PJ Flagellar assembly protein HHJ35_RS09875 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ35_RS09880 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HHJ35_RS09890 ENOG410814C multidrug resistance protein HHJ35_RS09895 ENOG4108V1U phospholipid-binding protein HHJ35_RS09900 ENOG4108UQN AraC family transcriptional regulator HHJ35_RS09915 ENOG4108RAV Conserved protein HHJ35_RS09925 ENOG41066VF YeeE YedE family protein HHJ35_RS09930 ENOG4108W9D (LipO)protein HHJ35_RS09935 ENOG4105E5K Alpha-amylase HHJ35_RS09945 ENOG4105MQ3 flagellar protein FliS HHJ35_RS09950 ENOG4105DTS flagellar hook-associated HHJ35_RS09955 ENOG4105I03 Flagellin HHJ35_RS09960 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ35_RS09965 ENOG4108M9K flagella biosynthesis protein FliZ HHJ35_RS09970 ENOG4105EAB amino acid AbC transporter HHJ35_RS09980 ENOG4105E5Q amino acid AbC transporter HHJ35_RS09985 ENOG4105CDA abc transporter atp-binding protein HHJ35_RS09990 ENOG4105VJY transcriptional regulator HHJ35_RS09995 ENOG4105XVG cytoplasmic protein HHJ35_RS10005 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ35_RS10035 ENOG4106RHG Yeca family HHJ35_RS10040 ENOG4105E0U tyrosine-specific transport protein HHJ35_RS10045 ENOG4105VVZ metal-binding protein HHJ35_RS10050 ENOG41090A1 ferritin HHJ35_RS10055 ENOG4105P23 (LipO)protein HHJ35_RS10065 ENOG4105N4N Protein of unknown function (DUF2766) HHJ35_RS10070 ENOG4108UEC Ferritin-like protein HHJ35_RS10075 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HHJ35_RS10085 ENOG4105CNN ABC, transporter HHJ35_RS10090 ENOG4108K4C ec 3.1.3.12 HHJ35_RS10100 ENOG4108VA4 Universal stress protein HHJ35_RS10110 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HHJ35_RS10115 ENOG4107RD7 Flagellar Motor Protein, MotA HHJ35_RS10120 ENOG4105ER2 Ompa motb domain protein HHJ35_RS10125 ENOG4105CBS Chea signal transduction histidine kinase HHJ35_RS10130 ENOG4108V3W Chemotaxis protein, CheW HHJ35_RS10135 ENOG4105C8Q Methyl-accepting chemotaxis HHJ35_RS10145 ENOG4105BZU Histidine kinase HHJ35_RS10150 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) HHJ35_RS10155 ENOG4108VYJ response regulator receiver protein HHJ35_RS10160 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HHJ35_RS10165 ENOG4105D00 flagellar biosynthetic protein flhB HHJ35_RS10170 ENOG4105D7B Flagellar biosynthesis protein flha HHJ35_RS10175 ENOG4105W13 flagellar protein HHJ35_RS10185 ENOG4106ZCM YecM protein HHJ35_RS10195 ENOG4105CUW cytochrome C-TYPE protein HHJ35_RS10215 ENOG4105WJG Glutathione HHJ35_RS10220 ENOG41081XQ Conserved Protein HHJ35_RS10225 ENOG4105D3W isochorismatase HHJ35_RS10235 ENOG4108TIT dATP pyrophosphohydrolase HHJ35_RS10240 ENOG4105CDY transcriptional regulatory protein HHJ35_RS10250 ENOG4107S01 Repressor protein MetJ HHJ35_RS10270 ENOG4105FAV ABC, transporter HHJ35_RS10280 ENOG4105NXV High-affinity zinc uptake system protein HHJ35_RS10285 ENOG4105DR5 peptidase HHJ35_RS10290 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HHJ35_RS10295 ENOG4105CA9 Pyruvate kinase HHJ35_RS10300 ENOG4106KNT transcriptional regulator HHJ35_RS10305 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HHJ35_RS10310 ENOG4105C01 Dihydroxy-acid dehydratase HHJ35_RS10315 ENOG4108UHU Aldolase HHJ35_RS10325 ENOG4105X2V dna damage-inducible protein HHJ35_RS10335 ENOG4108Q2J Inner membrane protein YebE HHJ35_RS10340 ENOG4105CUG Oligopeptidase b HHJ35_RS10345 ENOG4105UMD exodeoxyribonuclease X HHJ35_RS10350 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ35_RS10355 ENOG4105MPK DNA polymerase III subunit theta HHJ35_RS10360 ENOG4105FXM Copper resistance protein HHJ35_RS10365 ENOG4108PNC copper resistance HHJ35_RS10370 ENOG4105NKT exported protein HHJ35_RS10375 ENOG4108R1E Serine threonine protein phosphatase 1 HHJ35_RS10380 ENOG4105UVW uncharacterized protein yebW HHJ35_RS10385 ENOG4105WT8 Protein of unknown function (DUF1480) HHJ35_RS10395 ENOG4105DY2 Paraquat-inducible protein b HHJ35_RS10400 ENOG4105H2K paraquat-inducible protein a HHJ35_RS10405 ENOG4108ZGC gaf domain protein HHJ35_RS10415 ENOG4105CN1 protease HHJ35_RS10425 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ35_RS10430 ENOG4105J4Q Transcriptional regulator HHJ35_RS10435 ENOG4105TIK HHJ35_RS10445 ENOG4105Q3Y exported protein HHJ35_RS10460 ENOG4105DHI Methyltransferase HHJ35_RS10475 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ35_RS10480 ENOG4105ETZ PTS System HHJ35_RS10485 ENOG4105DAS pts system HHJ35_RS10490 ENOG4105EE5 Membrane protein terC HHJ35_RS10495 ENOG4107XTP (EAL) domain protein HHJ35_RS10500 ENOG4105EJQ L-serine dehydratase HHJ35_RS10510 ENOG4105CRQ synthase (Component I) HHJ35_RS10520 ENOG4105V2F Uncharacterized protein yoac HHJ35_RS10525 ENOG4105M4H endoribonuclease L-psp HHJ35_RS10530 ENOG4105DVT helicase HHJ35_RS10535 ENOG41072GX Peptidase M22 Glycoprotease HHJ35_RS10540 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ35_RS10545 ENOG4105CEY Amp-dependent synthetase and ligase HHJ35_RS10550 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HHJ35_RS10555 ENOG4105EJC lysr family transcriptional regulator HHJ35_RS10565 ENOG4108YS1 cytoplasmic protein HHJ35_RS10570 ENOG4105YP6 Domain of unknown function (DUF1869) HHJ35_RS10575 ENOG4105Y3U Transglycosylase-associated protein HHJ35_RS10585 ENOG4106G4W HHJ35_RS10590 ENOG410620I Diguanylate cyclase HHJ35_RS10595 ENOG4105UCG Domain of unknown function (DUF333) HHJ35_RS10600 ENOG4105K78 MarR family Transcriptional regulator HHJ35_RS10605 ENOG4105DJ2 Major Facilitator Superfamily HHJ35_RS10610 ENOG4105R1U AraC Family Transcriptional Regulator HHJ35_RS10625 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HHJ35_RS10630 ENOG4108KHP Diguanylate cyclase HHJ35_RS10635 ENOG4106KTS Inner membrane protein yeaI HHJ35_RS10645 ENOG4105CYN Serine protein kinase HHJ35_RS10650 ENOG4105GNX MltA-interacting MipA family protein HHJ35_RS10655 ENOG4105CV8 reductase HHJ35_RS10660 ENOG4105DSB aldose 1-epimerase HHJ35_RS10665 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ35_RS10675 ENOG4105VUT cytoplasmic protein HHJ35_RS10680 ENOG4105CPQ Dehydrogenase HHJ35_RS10685 ENOG4107TE1 transport protein HHJ35_RS10690 ENOG4105CPQ Dehydrogenase HHJ35_RS10695 ENOG4105D2N Aldolase HHJ35_RS10700 ENOG4107UH8 sugar kinase HHJ35_RS10705 ENOG4105CPC Aldo Keto reductase HHJ35_RS10710 ENOG4105E98 transcriptional regulator DeoR family HHJ35_RS10715 ENOG4108KUU Inner membrane metabolite transport protein ydjE HHJ35_RS10720 ENOG4108RWI nicotinamidase HHJ35_RS10725 ENOG4105HDK L-asparaginase HHJ35_RS10730 ENOG4105D07 Signal peptide peptidase, SppA HHJ35_RS10735 ENOG41069NU Nitroreductase HHJ35_RS10745 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ35_RS10750 ENOG4105D82 Glutamate dehydrogenase HHJ35_RS10755 ENOG4105MTM Protein of unknown function (DUF1496) HHJ35_RS10760 ENOG4105M6F mutator MutT protein HHJ35_RS10765 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HHJ35_RS10770 ENOG4107RM6 sulfurtransferase HHJ35_RS10775 ENOG4108VGW abc transporter atp-binding protein HHJ35_RS10780 ENOG4105CXZ ABC transporter, permease HHJ35_RS10785 ENOG4105VNH ABC transporter solute-binding protein HHJ35_RS10790 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HHJ35_RS10795 ENOG4108N5C SNARE associated Golgi protein-related protein HHJ35_RS10800 ENOG4108KCW iron-sulfur cluster binding HHJ35_RS10805 ENOG4108RSN SNARE associated Golgi HHJ35_RS10810 ENOG4105CGK Exodeoxyribonuclease III HHJ35_RS10840 ENOG4108SPG Periplasmic Protein HHJ35_RS10850 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HHJ35_RS10860 ENOG4105KKI DNA-binding transcriptional activator OsmE HHJ35_RS10865 ENOG4105VZJ PTS System HHJ35_RS10870 ENOG4105CK1 PTS System HHJ35_RS10875 ENOG4105VCP PTS System HHJ35_RS10880 ENOG4105EZV Transcriptional regulator HHJ35_RS10885 ENOG4105F8D glycoside hydrolase family 4 HHJ35_RS10895 ENOG4105CH6 catalase HHJ35_RS10905 ENOG4108ETY sodium dicarboxylate symporter HHJ35_RS10910 ENOG4107K5X Membrane-bound metal-dependent hydrolase HHJ35_RS10915 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HHJ35_RS10920 ENOG4107PN8 YfeABCD locus regulator HHJ35_RS10930 ENOG4105P10 Uncharacterized protein ydiZ HHJ35_RS10935 ENOG4105DE4 1-phosphofructokinase HHJ35_RS10940 ENOG4108NE3 Salt-induced outer membrane protein HHJ35_RS10960 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HHJ35_RS10965 ENOG41082NX 50s ribosomal protein l35 HHJ35_RS11000 ENOG4108V06 Glutathione peroxidase HHJ35_RS11010 ENOG4108QBX (LipO)protein HHJ35_RS11015 ENOG4108TC0 Diguanylate phosphodiesterase HHJ35_RS11030 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ35_RS11040 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HHJ35_RS11045 ENOG4105CEY Amp-dependent synthetase and ligase HHJ35_RS11050 ENOG41090P5 ferredoxin-like protein HHJ35_RS11055 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ35_RS11060 ENOG4105C10 Electron transfer flavoprotein HHJ35_RS11065 ENOG4105CV7 Electron transfer flavoprotein HHJ35_RS11070 ENOG4105W4W Transcriptional regulator HHJ35_RS11075 ENOG4105C1G acyl-Coa dehydrogenase HHJ35_RS11080 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ35_RS11095 ENOG4105EMV Major Facilitator HHJ35_RS11100 ENOG4105EMV Major Facilitator HHJ35_RS11105 ENOG4105SUA Ydil protein HHJ35_RS11115 ENOG4105IPI Membrane HHJ35_RS11120 ENOG4105CQB FAD linked oxidase domain protein HHJ35_RS11125 ENOG4105KA0 thioesterase Superfamily protein HHJ35_RS11130 ENOG410671Z uncharacterized protein ydiH HHJ35_RS11135 ENOG4108Z4V iron-sulfur cluster assembly HHJ35_RS11140 ENOG4105DIW FeS assembly protein SUFB HHJ35_RS11145 ENOG4105C3K feS assembly ATPase SufC HHJ35_RS11150 ENOG4105JRK feS assembly protein SufD HHJ35_RS11165 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ35_RS11170 ENOG4105KMX major outer membrane lipoprotein HHJ35_RS11175 ENOG4105CA9 Pyruvate kinase HHJ35_RS11180 ENOG4105RFR Protein of unknown function (DUF2767) HHJ35_RS11185 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein HHJ35_RS11190 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HHJ35_RS11195 ENOG4105JVW HHJ35_RS11200 ENOG4108393 oxidoreductase Fe-S subunit HHJ35_RS11205 ENOG4108NWD Cytochrome HHJ35_RS11210 ENOG4108Y7C Conserved Protein HHJ35_RS11215 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HHJ35_RS11220 ENOG4105N0V mono-oxygenase ydhR HHJ35_RS11245 ENOG4108R6K riboflavin synthase, subunit alpha HHJ35_RS11250 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HHJ35_RS11255 ENOG4105CZQ inner membrane transport protein YdhC HHJ35_RS11260 ENOG4105F52 Transcriptional regulator HHJ35_RS11275 ENOG4105F27 Major Facilitator HHJ35_RS11280 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ35_RS11285 ENOG4105K4H Nlp p60 protein HHJ35_RS11290 ENOG4105M2J Glutaredoxin HHJ35_RS11300 ENOG4108UYE Lactoylglutathione lyase HHJ35_RS11305 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ35_RS11310 ENOG4108WUH Transcriptional regulator, TetR family HHJ35_RS11315 ENOG4105XZD Fe-S protein HHJ35_RS11320 ENOG4107RGM aldo keto reductase HHJ35_RS11325 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ35_RS11330 ENOG4105DSW Fusaric acid resistance protein HHJ35_RS11335 ENOG4105Y49 secretion protein, HlyD family HHJ35_RS11350 ENOG4108XTF Outer Membrane Lipoprotein HHJ35_RS11360 ENOG410642K Lysozyme inhibitor HHJ35_RS11375 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HHJ35_RS11380 ENOG4108K3A Glutathione S-transferase HHJ35_RS11385 ENOG4105DUX Transporter HHJ35_RS11390 ENOG4105CSM endonuclease III HHJ35_RS11400 ENOG4108UQQ Electron transport complex HHJ35_RS11425 ENOG4105M9B inner membrane protein ydgK HHJ35_RS11430 ENOG4105QZ5 OriC-binding nucleoid-associated protein HHJ35_RS11435 ENOG4106C6R beta-lactam resistance protein HHJ35_RS11440 ENOG4105D9R oxidoreductase HHJ35_RS11450 ENOG4105C87 Aminotransferase class I and II HHJ35_RS11455 ENOG4105CI1 PTS System HHJ35_RS11460 ENOG4107P2S Transcriptional regulator HHJ35_RS11465 ENOG4107ZQV short-chain dehydrogenase reductase HHJ35_RS11470 ENOG4105XEA Tetr family transcriptional regulator HHJ35_RS11475 ENOG4105CNT hydrolase family 2 HHJ35_RS11480 ENOG4105CT4 transporter HHJ35_RS11485 ENOG4108QNI outer membrane porin protein HHJ35_RS11490 ENOG4106J39 exported protein HHJ35_RS11495 ENOG4105EIP mannose-6-phosphate isomerase HHJ35_RS11500 ENOG4107GFK fumarate HHJ35_RS11505 ENOG4105C9Q fumarate hydratase class II HHJ35_RS11515 ENOG4105JJR Histidine kinase HHJ35_RS11520 ENOG4107EXC regulatoR HHJ35_RS11525 ENOG4105RA2 Membrane HHJ35_RS11535 ENOG4105D5Q Arginine ornithine antiporter HHJ35_RS11540 ENOG4105C5D exported protein HHJ35_RS11545 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ35_RS11550 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ35_RS11555 ENOG4105DSF transport protein HHJ35_RS11570 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HHJ35_RS11585 ENOG4105D94 Major Facilitator Superfamily HHJ35_RS11590 ENOG4106NZI LysR family Transcriptional regulator HHJ35_RS11595 ENOG4105DAG ROK family HHJ35_RS11600 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ35_RS11610 ENOG4108NEM leader-binding protein dmsD HHJ35_RS11615 ENOG4107KGK dmso reductase anchor subunit HHJ35_RS11620 ENOG4105QAX Iron-sulfur HHJ35_RS11625 ENOG4105C3J Cysteine desulfurase HHJ35_RS11630 ENOG4107QY8 reductase HHJ35_RS11635 ENOG4105KBG Protein of unknown function (DUF1161) HHJ35_RS11645 ENOG4108MK9 spermidine N(1)-acetyltransferase HHJ35_RS11660 ENOG4105CXK mandelate racemase muconate lactonizing HHJ35_RS11665 ENOG4105CPQ Dehydrogenase HHJ35_RS11680 ENOG4105DEI Mannitol dehydrogenase HHJ35_RS11685 ENOG41061EV selenium-binding protein YdfZ HHJ35_RS11690 ENOG4107XBN GntR Family Transcriptional Regulator HHJ35_RS11695 ENOG4105EMU Dehydrogenase HHJ35_RS11700 ENOG4105DGW oligopeptidase A HHJ35_RS11705 ENOG4108YDI single-species biofilm formation on inanimate substrate HHJ35_RS11710 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria HHJ35_RS11720 ENOG4105E5W Transporter HHJ35_RS11725 ENOG4108594 Permease of the drug metabolite transporter HHJ35_RS11730 ENOG4105FDP GntR family transcriptional regulator HHJ35_RS11740 ENOG4105CK1 PTS System HHJ35_RS11745 ENOG4105VCP PTS System HHJ35_RS11755 ENOG4105CS2 ec 3.2.1.21 HHJ35_RS11760 ENOG4106DNR multiple antibiotic resistance protein HHJ35_RS11765 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HHJ35_RS11770 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HHJ35_RS11790 ENOG4105EGI Transcriptional regulator HHJ35_RS11795 ENOG4105C26 Dehydrogenase HHJ35_RS11800 ENOG4105CSV Glutaminase HHJ35_RS11805 ENOG4105M0C cytoplasmic protein HHJ35_RS11810 ENOG4105BZU Histidine kinase HHJ35_RS11820 ENOG4105FFC UPF0187 protein HHJ35_RS11830 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein HHJ35_RS11835 ENOG4105CAF HipA N-terminal domain protein HHJ35_RS11845 ENOG4105CGD Nad-dependent epimerase dehydratase HHJ35_RS11850 ENOG4108RQP Major type 1 subunit fimbrin HHJ35_RS11860 ENOG4105CW0 outer membrane usher protein HHJ35_RS11865 ENOG4108WDE Fimbrial protein HHJ35_RS11870 ENOG4106318 fimbrial-like protein YdeR HHJ35_RS11875 ENOG4106PIH fimbrial-like protein ydeQ HHJ35_RS11880 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HHJ35_RS11890 ENOG4108NKV transcriptional regulator HHJ35_RS11895 ENOG4105ENH Sulfatase HHJ35_RS11900 ENOG4105C4X radical SAM domain protein HHJ35_RS11910 ENOG4105CQ0 ABC transporter HHJ35_RS11915 ENOG4105PE1 Receptor HHJ35_RS11920 ENOG4107RAN Peptidase, M16 HHJ35_RS11925 ENOG4105CVK Glutamate decarboxylase HHJ35_RS11930 ENOG4105E5D amino acid HHJ35_RS11935 ENOG4105F32 YngK protein HHJ35_RS11940 ENOG4105BZU Histidine kinase HHJ35_RS11940 ENOG4105BZU Histidine kinase HHJ35_RS11945 ENOG4105BZU Histidine kinase HHJ35_RS11950 ENOG4108Z9K Osmotically inducible protein HHJ35_RS11955 ENOG4105TPS biofilm-dependent modulation protein HHJ35_RS11960 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HHJ35_RS11970 ENOG4105DQ4 alcohol dehydrogenase HHJ35_RS11980 ENOG41084S7 Plasmid maintenance system antidote protein HHJ35_RS11985 ENOG4108MG3 formate dehydrogenase HHJ35_RS11990 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ35_RS12000 ENOG4105RPH Inner membrane protein YddG HHJ35_RS12005 ENOG4107QND Nitrite extrusion protein HHJ35_RS12010 ENOG4105CRU nitrate reductase, alpha subunit HHJ35_RS12015 ENOG4108IUE nitrate reductase beta subunit HHJ35_RS12020 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HHJ35_RS12025 ENOG4105D0D Nitrate reductase 2, gamma subunit HHJ35_RS12030 ENOG4105JAB phenazine biosynthesis protein, phzf family HHJ35_RS12035 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HHJ35_RS12040 ENOG4108MEJ flavin reductase domain protein HHJ35_RS12085 ENOG4108N27 Glutathione S-transferase HHJ35_RS12090 ENOG4108N27 Glutathione S-transferase HHJ35_RS12095 ENOG4105C85 amino acid HHJ35_RS12100 ENOG4108NS2 receptor HHJ35_RS12105 ENOG4105CHB tonB-dependent Receptor HHJ35_RS12120 ENOG4108Z7F N-acetyltransferase HHJ35_RS12125 ENOG4108T9Y Inner membrane protein ydcZ HHJ35_RS12130 ENOG4105R71 cytoplasmic protein HHJ35_RS12135 ENOG410654E Membrane HHJ35_RS12150 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HHJ35_RS12155 ENOG4105D81 ABC transporter, permease HHJ35_RS12160 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ35_RS12165 ENOG4107TYH extracellular solute-binding protein family 1 HHJ35_RS12170 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HHJ35_RS12180 ENOG4105RR0 Protein of unknown function (DUF2554) HHJ35_RS12185 ENOG4105CFP Peptidase U32 HHJ35_RS12190 ENOG4108JCI Transcriptional regulator HHJ35_RS12195 ENOG4105DKK Benzoate HHJ35_RS12200 ENOG4108KKZ (LipO)protein HHJ35_RS12205 ENOG41088CC tellurite resistance protein tehB HHJ35_RS12210 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HHJ35_RS12215 ENOG4107WE3 acetyltransferase YdcK HHJ35_RS12220 ENOG4108Z9I -acetyltransferase HHJ35_RS12225 ENOG4105Z2P Protein of unknown function (DUF465) HHJ35_RS12235 ENOG4105E32 cytoplasmic protein HHJ35_RS12240 ENOG4105DDW LysR family Transcriptional regulator HHJ35_RS12250 ENOG4107NK6 Hok/gef family HHJ35_RS12255 ENOG4105UPP uncharacterized protein ydcA HHJ35_RS12260 ENOG4105CPW cytochrome b561 HHJ35_RS12265 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ35_RS12270 ENOG4105C26 Dehydrogenase HHJ35_RS12275 ENOG4107DB1 DUF218 domain HHJ35_RS12280 ENOG4105CQ7 ATP-dependent helicase HHJ35_RS12290 ENOG41077RS Phosphatase HHJ35_RS12295 ENOG4105E8V Alpha Beta Hydrolase Fold protein HHJ35_RS12300 ENOG4108HPI phosphatidate Cytidylyltransferase HHJ35_RS12305 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase HHJ35_RS12310 ENOG4107S5I aldo keto reductase HHJ35_RS12315 ENOG4107EF2 surface-exposed virulence protein HHJ35_RS12320 ENOG4105WXT Conserved Protein HHJ35_RS12325 ENOG410689M (LipO)protein HHJ35_RS12330 ENOG4107H52 Dicarboxylate transport HHJ35_RS12335 ENOG4105C5I Dehydrogenase HHJ35_RS12340 ENOG41090X5 Heat shock protein hslJ HHJ35_RS12345 ENOG4105IKK cytoplasmic protein HHJ35_RS12350 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HHJ35_RS12355 ENOG4105FCK Membrane HHJ35_RS12360 ENOG4108RW8 Universal stress protein F HHJ35_RS12385 ENOG4105C1J atp-dependent rna helicase HHJ35_RS12395 ENOG4105BZU Histidine kinase HHJ35_RS12400 ENOG4108DG9 Smr protein MutS2 HHJ35_RS12415 ENOG4105R1U AraC Family Transcriptional Regulator HHJ35_RS12425 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ35_RS12430 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HHJ35_RS12435 ENOG4105Q9Y Universal stress protein HHJ35_RS12440 ENOG4105S5I Membrane HHJ35_RS12445 ENOG4105D64 Mechanosensitive ion channel HHJ35_RS12450 ENOG4107QSI ABC, transporter HHJ35_RS12455 ENOG4105EQ2 LysR family Transcriptional regulator HHJ35_RS12460 ENOG4105ENX hydrolase HHJ35_RS12475 ENOG4105KXI murein peptide amidase A HHJ35_RS12480 ENOG4107S8C mandelate racemase muconate lactonizing HHJ35_RS12485 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HHJ35_RS12490 ENOG4108JU8 Transcriptional regulator HHJ35_RS12500 ENOG4105CM6 amino acid regulated cytosolic protein HHJ35_RS12505 ENOG4105FKQ transcriptional regulator HHJ35_RS12510 ENOG4107EFV Outer membrane protein G HHJ35_RS12520 ENOG4107URF beta-phospho-glucomutase HHJ35_RS12525 ENOG4105C71 hydrolase family 65, central catalytic HHJ35_RS12530 ENOG4105CK5 oxidoreductase HHJ35_RS12535 ENOG4107TYA transient receptor potential locus HHJ35_RS12540 ENOG4107RRD Dehydrogenase HHJ35_RS12545 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component HHJ35_RS12550 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component HHJ35_RS12555 ENOG4105WEM extracellular solute-binding protein HHJ35_RS12560 ENOG4107QW3 Sucrose phosphorylase HHJ35_RS12565 ENOG4105K8Z Phage shock protein HHJ35_RS12570 ENOG4105NNG Peripheral inner membrane phage-shock protein HHJ35_RS12575 ENOG4105FM1 phage shock protein C HHJ35_RS12580 ENOG4105YYT phage shock protein B HHJ35_RS12585 ENOG41087YS Phage shock protein A HHJ35_RS12590 ENOG4105E51 psp operon transcriptional activator HHJ35_RS12600 ENOG4105N0E Protein of unknown function (DUF2543) HHJ35_RS12605 ENOG4108HIY periplasmic HHJ35_RS12610 ENOG4108I5W peptide transport system, permease protein HHJ35_RS12615 ENOG4108EU3 peptide transport system, permease HHJ35_RS12620 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HHJ35_RS12625 ENOG4108JQ2 peptide transport system atp-binding protein HHJ35_RS12630 ENOG4105C2C drug resistance transporter, Bcr CflA HHJ35_RS12635 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HHJ35_RS12640 ENOG4105BZS acriflavin resistance protein HHJ35_RS12645 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ35_RS12650 ENOG41067SE Tetr family transcriptional regulator HHJ35_RS12655 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HHJ35_RS12660 ENOG4105Q4T oxidoreductase HHJ35_RS12675 ENOG4105BZU Histidine kinase HHJ35_RS12680 ENOG410643D UPF0509 protein HHJ35_RS12685 ENOG4105N2W Transcriptional regulator HHJ35_RS12695 ENOG4108ZJT translation initiation factor, Sui1 HHJ35_RS12705 ENOG4105CFV Tetratricopeptide repeat protein HHJ35_RS12710 ENOG4105Q4A inner membrane protein yciS HHJ35_RS12715 ENOG4105EYK Phosphatidylglycerophosphatase B HHJ35_RS12725 ENOG4107QM5 aconitate hydratase HHJ35_RS12745 ENOG4107R11 Transcriptional regulator HHJ35_RS12750 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ35_RS12755 ENOG4105RKX Protein of unknown function (DUF2498) HHJ35_RS12760 ENOG4105ERU peptidase HHJ35_RS12765 ENOG4105UBK short-chain dehydrogenase reductase HHJ35_RS12770 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HHJ35_RS12775 ENOG4105FE9 pseudouridine synthase HHJ35_RS12780 ENOG4105EG3 transmembrane signal peptide protein HHJ35_RS12785 ENOG4107RTD sua5 ycio yrdc ywlc family protein HHJ35_RS12790 ENOG4105DB7 PHP domain protein HHJ35_RS12800 ENOG4105CRQ synthase (Component I) HHJ35_RS12805 ENOG4108EFP Anthranilate synthase component II HHJ35_RS12810 ENOG4105DK0 Indole-3-glycerol phosphate synthase HHJ35_RS12830 ENOG4108Z9Z response to DNA damage stimulus HHJ35_RS12835 ENOG4108N8X transition metal ion binding HHJ35_RS12855 ENOG4108WF3 methyltransferase HHJ35_RS12860 ENOG4105UZW Tail fiber assembly protein HHJ35_RS12865 ENOG4108X9F tail fiber protein HHJ35_RS12945 ENOG4105IM0 capsid protein HHJ35_RS12970 ENOG4105UZW Tail fiber assembly protein HHJ35_RS12980 ENOG4106YSC HHJ35_RS12985 ENOG41064WM Uncharacterized protein YcgX HHJ35_RS12990 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HHJ35_RS13010 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HHJ35_RS13045 ENOG4105HGD Antitermination protein HHJ35_RS13050 ENOG4105KSK (crossover) junction endodeoxyribonuclease HHJ35_RS13055 ENOG4108MXB Protein of unknown function (DUF968) HHJ35_RS13090 ENOG4108PM0 it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity) HHJ35_RS13130 ENOG4106G8A Qin prophage HHJ35_RS13145 ENOG4108I1J Integrase HHJ35_RS13150 ENOG4105EIF outer membrane protein W HHJ35_RS13170 ENOG4105NAU thioesterase Superfamily protein HHJ35_RS13175 ENOG410822N TonB family HHJ35_RS13180 ENOG4105K9H YciI-like protein HHJ35_RS13185 ENOG4107SVH Potassium channel protein HHJ35_RS13205 ENOG4108JQ7 (ABC) transporter HHJ35_RS13210 ENOG4105C3U ABC transporter HHJ35_RS13215 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ35_RS13220 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ35_RS13225 ENOG4108J59 Extracellular solute-binding protein, family 5 HHJ35_RS13230 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HHJ35_RS13235 ENOG4105C0A alcohol dehydrogenase HHJ35_RS13245 ENOG4107104 thymidine kinase HHJ35_RS13250 ENOG4108SAU DNA-binding protein H-ns HHJ35_RS13255 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ35_RS13260 ENOG4105I93 response regulator HHJ35_RS13265 ENOG4105D78 K07001 NTE family protein HHJ35_RS13275 ENOG4105CIY formyltetrahydrofolate deformylase HHJ35_RS13300 ENOG41076YT nitrate reductase, gamma subunit HHJ35_RS13305 ENOG4105R3A Nitrate reductase HHJ35_RS13310 ENOG4108IUE nitrate reductase beta subunit HHJ35_RS13315 ENOG4105CRU nitrate reductase, alpha subunit HHJ35_RS13320 ENOG4105DQQ Major facilitator superfamily MFS_1 HHJ35_RS13325 ENOG4105BZU Histidine kinase HHJ35_RS13330 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ35_RS13335 ENOG4105ID0 Putative invasin HHJ35_RS13340 ENOG41090EX DsrE family HHJ35_RS13345 ENOG4108NH8 Cation transport protein HHJ35_RS13350 ENOG4105WS7 Cation transport regulator HHJ35_RS13355 ENOG4105EWV Sodium calcium exchanger membrane region HHJ35_RS13370 ENOG41063JG Transcriptional regulator HHJ35_RS13375 ENOG4108YY7 Invasion gene expression up-regulator SirB HHJ35_RS13380 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HHJ35_RS13405 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HHJ35_RS13410 ENOG4105CHH sulfate transporter HHJ35_RS13415 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HHJ35_RS13425 ENOG4105C3G gtp-binding protein HHJ35_RS13435 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HHJ35_RS13440 ENOG4105CMT Dihydroxyacetone kinase HHJ35_RS13445 ENOG4108UTZ Dihydroxyacetone kinase HHJ35_RS13450 ENOG4105VDH Dihydroxyacetone kinase HHJ35_RS13465 ENOG4105S10 periplasmic binding protein HHJ35_RS13470 ENOG4105EHG Permease protein HHJ35_RS13475 ENOG4105E0A ABC, transporter HHJ35_RS13480 ENOG4108BSC Methyltransferase HHJ35_RS13485 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HHJ35_RS13500 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HHJ35_RS13510 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HHJ35_RS13520 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ35_RS13530 ENOG4105ED1 spovr family HHJ35_RS13550 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HHJ35_RS13555 ENOG4105KT5 UmuD protein HHJ35_RS13565 ENOG4108ZZ3 UPF0260 protein HHJ35_RS13570 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HHJ35_RS13580 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HHJ35_RS13585 ENOG4105S66 prophage protein HHJ35_RS13595 ENOG4107QMS site-determining protein HHJ35_RS13630 ENOG410658X HHJ35_RS13650 ENOG410738I uncharacterized protein ymgC HHJ35_RS13660 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB HHJ35_RS13665 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component HHJ35_RS13670 ENOG4105BZU Histidine kinase HHJ35_RS13675 ENOG4108XDN Transcriptional regulator HHJ35_RS13680 ENOG41064WM Uncharacterized protein YcgX HHJ35_RS13690 ENOG4108HMX isocitrate dehydrogenase (NADP) HHJ35_RS13715 ENOG4107QTF adenylosuccinate lyase HHJ35_RS13720 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ35_RS13725 ENOG4105IFJ Histidine kinase HHJ35_RS13730 ENOG4105EZE Cupin 4 family protein HHJ35_RS13750 ENOG4105D38 putrescine abc transporter HHJ35_RS13755 ENOG4107RUE extracellular solute-binding protein family 1 HHJ35_RS13770 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HHJ35_RS13780 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ35_RS13785 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HHJ35_RS13790 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ35_RS13795 ENOG4105IQC Inner membrane protein YcfT HHJ35_RS13800 ENOG4108JA2 transcriptioN-repair coupling factor HHJ35_RS13805 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ35_RS13810 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HHJ35_RS13815 ENOG4108IND Tetr family transcriptional regulator HHJ35_RS13820 ENOG4107MBR 17 kDa surface antigen HHJ35_RS13825 ENOG4105CEP NADH dehydrogenase HHJ35_RS13845 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HHJ35_RS13850 ENOG41090DQ Lipoprotein HHJ35_RS13855 ENOG4105K59 histidine triad (HIT) protein HHJ35_RS13860 ENOG4105CNM Receptor HHJ35_RS13865 ENOG4105CI1 PTS System HHJ35_RS13870 ENOG4105F8V Hydrolase, tatD family HHJ35_RS13875 ENOG4107QRG dna polymerase iii HHJ35_RS13885 ENOG4105HHA aminodeoxychorismate lyase HHJ35_RS13890 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HHJ35_RS13895 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ35_RS13900 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ35_RS13905 ENOG4105CHR reductase HHJ35_RS13910 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HHJ35_RS13930 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HHJ35_RS13935 ENOG4108UHJ MAF-like protein HHJ35_RS13940 ENOG4105EI2 Pseudouridine synthase HHJ35_RS13945 ENOG4107QQB Ribonuclease E HHJ35_RS13950 ENOG4105DTJ flagellar hook-associated protein HHJ35_RS13955 ENOG4105E1Q flagellar hook-associated protein HHJ35_RS13975 ENOG4105CGA flagellar basal-body rod protein FlgG HHJ35_RS13980 ENOG4108KPB Flagellar basal-body rod protein FlgF HHJ35_RS13985 ENOG4105BZE flagellar hook protein, FlgE HHJ35_RS13990 ENOG4105W00 Flagellar hook capping protein HHJ35_RS13995 ENOG4108ZC9 flagellar basal-body rod protein flgc HHJ35_RS14000 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HHJ35_RS14005 ENOG4105CKS Flagella basal body P-ring formation protein flgA HHJ35_RS14010 ENOG4105M9M anti-sigma28 factor FlgM HHJ35_RS14015 ENOG4105QVD Flagella synthesis protein FlgN HHJ35_RS14020 ENOG4105CJR Integral membrane protein (MviN HHJ35_RS14025 ENOG4105EP9 oxidoreductase HHJ35_RS14035 ENOG4105D9U N-acetyltransferase HHJ35_RS14045 ENOG4105E9S glutaredoxin 2 HHJ35_RS14050 ENOG4105F3T (LipO)protein HHJ35_RS14060 ENOG4105MEA DNA damage-inducible protein i HHJ35_RS14065 ENOG4105PVA Biofilm formation regulatory protein BssS HHJ35_RS14075 ENOG4106974 biofilm formation HHJ35_RS14080 ENOG4105DS1 cytochrome b561 HHJ35_RS14085 ENOG4108YYC ycei family HHJ35_RS14095 ENOG4105D1S lipid A biosynthesis HHJ35_RS14105 ENOG4108W47 Acidic protein msyB HHJ35_RS14110 ENOG4105NAC (LipO)protein HHJ35_RS14115 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HHJ35_RS14130 ENOG4107RZC phospholipase d HHJ35_RS14135 ENOG4108UVJ appr-1-p processing domain protein HHJ35_RS14150 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HHJ35_RS14155 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HHJ35_RS14160 ENOG41086KC Transcriptional regulator HHJ35_RS14165 ENOG4108XDW curli assembly protein CsgE HHJ35_RS14170 ENOG4108WYR Curli production assembly transport component, CsgF HHJ35_RS14175 ENOG4105P8Q Curli production assembly transport component CsgG HHJ35_RS14180 ENOG4108UQ5 membrane protein YcdZ HHJ35_RS14185 ENOG4107XHZ cytoplasmic chaperone TorD family protein HHJ35_RS14205 ENOG4105BZU Histidine kinase HHJ35_RS14210 ENOG4108TUY outer membrane protein PgaA HHJ35_RS14215 ENOG4107BJW polysaccharide deacetylase HHJ35_RS14220 ENOG4105CND Glycosyl transferase, family 2 HHJ35_RS14230 ENOG4105D5M phosphate starvation-inducible protein HHJ35_RS14245 ENOG4105EKT )-iron permease HHJ35_RS14250 ENOG4105CK7 Sodium proline symporter HHJ35_RS14260 ENOG4105C26 Dehydrogenase HHJ35_RS14265 ENOG4108R86 Transcriptional regulator HHJ35_RS14305 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HHJ35_RS14315 ENOG4105XH3 HHJ35_RS14320 ENOG4105D6F Phosphatase HHJ35_RS14340 ENOG4108EM1 reductase HHJ35_RS14345 ENOG4105CUW cytochrome C-TYPE protein HHJ35_RS14350 ENOG4106WF9 DNA-binding transcriptional regulator TorR HHJ35_RS14355 ENOG4108SV3 Tmao reductase system periplasmic protein tort HHJ35_RS14360 ENOG4105BZU Histidine kinase HHJ35_RS14365 ENOG4105HEE Binding Domain protein HHJ35_RS14370 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HHJ35_RS14385 ENOG4105VEQ Cold shock protein HHJ35_RS14390 ENOG41060EU Cold shock-like protein HHJ35_RS14395 ENOG4105D6F Phosphatase HHJ35_RS14405 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ35_RS14410 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ35_RS14415 ENOG4105MVP hydrogenase-1 operon protein HyaF HHJ35_RS14420 ENOG4108VXY Hydrogenase-1 operon protein HyaE HHJ35_RS14425 ENOG4108USZ hydrogenase HHJ35_RS14430 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HHJ35_RS14435 ENOG4105DPX Hydrogenase, large subunit HHJ35_RS14440 ENOG4105E3S small subunit HHJ35_RS14450 ENOG4108MN8 Membrane HHJ35_RS14455 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HHJ35_RS14475 ENOG4105K4P CoA-binding domain protein HHJ35_RS14490 ENOG41088T4 Helicase IV HHJ35_RS14495 ENOG410901E Membrane HHJ35_RS14500 ENOG4105EM2 membrane HHJ35_RS14505 ENOG4108RZ1 DNA transformation protein HHJ35_RS14515 ENOG4105UYK outer membrane protein a HHJ35_RS14525 ENOG4105DAN ATP-dependent protease HHJ35_RS14535 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HHJ35_RS14540 ENOG4108Q2G (LipO)protein HHJ35_RS14545 ENOG4105DY2 Paraquat-inducible protein b HHJ35_RS14550 ENOG4105F1S paraquat-inducible protein a HHJ35_RS14555 ENOG4105C5H ABC transporter HHJ35_RS14565 ENOG4105QVC MOSC domain-containing protein HHJ35_RS14570 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HHJ35_RS14580 ENOG4108UZX fmn reductase HHJ35_RS14585 ENOG4105GVF (ABC) transporter HHJ35_RS14595 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HHJ35_RS14605 ENOG4105CD8 aminopeptidase N HHJ35_RS14625 ENOG4105CGF Aromatic amino acid aminotransferase HHJ35_RS14630 ENOG4105C5X domain protein HHJ35_RS14635 ENOG4105EAQ (twin-arginine translocation) pathway signal HHJ35_RS14650 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HHJ35_RS14660 ENOG4106371 Methyltransferase HHJ35_RS14665 ENOG4107S90 membrAne HHJ35_RS14670 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HHJ35_RS14685 ENOG4105T0Z Conserved Protein HHJ35_RS14695 ENOG4105BZ1 (ABC) transporter HHJ35_RS14700 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HHJ35_RS14710 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HHJ35_RS14720 ENOG4108K0D peptidase, M48 HHJ35_RS14735 ENOG4107VMU Membrane HHJ35_RS14740 ENOG4105DDY UPF0142 protein ycaO HHJ35_RS14745 ENOG4105TMB Formate nitrite transporter HHJ35_RS14750 ENOG4105C6N Formate acetyltransferase HHJ35_RS14755 ENOG4105F1A Pyruvate formate-lyase HHJ35_RS14765 ENOG4105CHJ isochorismatase hydrolase HHJ35_RS14770 ENOG4107KGK dmso reductase anchor subunit HHJ35_RS14775 ENOG4105QAX Iron-sulfur HHJ35_RS14780 ENOG4107QY8 reductase HHJ35_RS14790 ENOG4105D1H recombination factor protein RarA HHJ35_RS14800 ENOG4105CNU cell division protein FtsK HHJ35_RS14810 ENOG4105C3M thioredoxin reductase HHJ35_RS14815 ENOG4108JJ9 ABC, transporter HHJ35_RS14820 ENOG4108JJ8 (ABC) transporter HHJ35_RS14830 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HHJ35_RS14845 ENOG4105M6W Crispr-associated protein, Csy3 family HHJ35_RS14855 ENOG4105ENG CRISPR-associated protein, Csy1 family HHJ35_RS14860 ENOG4107IIZ CRISPR-associated helicase, Cas3 HHJ35_RS14865 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HHJ35_RS14870 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ35_RS14885 ENOG4105FKG DNA packaging protein HHJ35_RS14900 ENOG4105IM0 capsid protein HHJ35_RS14945 ENOG410679B prophage CP4-57 regulatory protein alpA HHJ35_RS14955 ENOG4105VEQ Cold shock protein HHJ35_RS14965 ENOG4105DJY efflux transporter, rnd family, mfp subunit HHJ35_RS14970 ENOG4108MJ5 VirK protein HHJ35_RS14975 ENOG4105CPB ATP-dependent endonuclease of the OLD family HHJ35_RS14980 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ35_RS14985 ENOG4105DWU Membrane HHJ35_RS14995 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ35_RS15000 ENOG4105C7K acetolactate synthase HHJ35_RS15005 ENOG4105C5W Aldolase HHJ35_RS15010 ENOG4105CGD Nad-dependent epimerase dehydratase HHJ35_RS15015 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HHJ35_RS15020 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ35_RS15030 ENOG41064MM (LipO)protein HHJ35_RS15035 ENOG4105E5Z arginine transporter ATP-binding subunit HHJ35_RS15040 ENOG4106PMH Extracellular solute-binding protein family 3 HHJ35_RS15045 ENOG4105GBT ABC transporter HHJ35_RS15050 ENOG4105DMR ABC, transporter HHJ35_RS15055 ENOG4106TNF Periplasmic binding protein HHJ35_RS15065 ENOG4105RBQ inner membrane protein ybjO HHJ35_RS15070 ENOG4105D38 putrescine abc transporter HHJ35_RS15075 ENOG4105F38 ABC transporter, permease HHJ35_RS15080 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ35_RS15085 ENOG4107RUE extracellular solute-binding protein family 1 HHJ35_RS15090 ENOG4108RMJ sensory transduction regulator HHJ35_RS15100 ENOG4108DBC nitroreductase HHJ35_RS15105 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HHJ35_RS15110 ENOG41090BQ Glutaredoxin HHJ35_RS15115 ENOG4105GWF inner membrane protein YbjM HHJ35_RS15125 ENOG4108RFG Tetr family transcriptional regulator HHJ35_RS15130 ENOG4106UW1 Major Facilitator superfamily HHJ35_RS15135 ENOG4108HCJ Hydrolase HHJ35_RS15145 ENOG4107QF7 multi-drug HHJ35_RS15150 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HHJ35_RS15155 ENOG4107FB0 transcriptional regulator DeoR family HHJ35_RS15160 ENOG4105DZ1 carboxypeptidase HHJ35_RS15165 ENOG4108TGY Glutathione S-transferase HHJ35_RS15170 ENOG4105D8V Glucose sorbosone dehydrogenase HHJ35_RS15175 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HHJ35_RS15185 ENOG41064RH membrane protein YliF HHJ35_RS15190 ENOG4105BZU Histidine kinase HHJ35_RS15215 ENOG4105D44 asparaginase HHJ35_RS15220 ENOG4105CVM Molybdenum cofactor synthesis domain protein HHJ35_RS15225 ENOG4105D06 uba thif-type nad fad binding protein HHJ35_RS15230 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ35_RS15235 ENOG4105F1A Pyruvate formate-lyase HHJ35_RS15245 ENOG4108HCJ Hydrolase HHJ35_RS15250 ENOG4105C5H ABC transporter HHJ35_RS15255 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ35_RS15260 ENOG4105F4P )-transporter HHJ35_RS15265 ENOG4105KST dependent repressor HHJ35_RS15275 ENOG4108I6E Sulfatase HHJ35_RS15280 ENOG4108T1M outer membrane protein x HHJ35_RS15290 ENOG4107AQZ Membrane HHJ35_RS15300 ENOG4107R0W ABC transporter HHJ35_RS15305 ENOG4105E5Q amino acid AbC transporter HHJ35_RS15310 ENOG4105CDA abc transporter atp-binding protein HHJ35_RS15315 ENOG4105D8X mechanosensitive ion channel HHJ35_RS15325 ENOG4105ZY9 UPF0379 protein ybiM HHJ35_RS15340 ENOG4105KSC Transcriptional regulator, TraR DksA family HHJ35_RS15345 ENOG4105VR4 UPF0379 protein ybiJ HHJ35_RS15350 ENOG4105DG4 malate L-lactate dehydrogenase HHJ35_RS15355 ENOG4108MTB glycosyl transferase family HHJ35_RS15360 ENOG4105DVT helicase HHJ35_RS15370 ENOG4105C1J atp-dependent rna helicase HHJ35_RS15375 ENOG4107MVR Transcriptional regulator HHJ35_RS15380 ENOG4105D0S secretion protein (HlyD HHJ35_RS15385 ENOG4105CJ1 ABC, transporter HHJ35_RS15390 ENOG4107QWP ABC-2 type transporter HHJ35_RS15395 ENOG4107QWP ABC-2 type transporter HHJ35_RS15400 ENOG4105I9U inner membrane protein ybhQ HHJ35_RS15405 ENOG4105X23 Endonuclease Exonuclease phosphatase HHJ35_RS15410 ENOG4105DZQ phospholipase D Transphosphatidylase HHJ35_RS15415 ENOG4107UXM Membrane HHJ35_RS15420 ENOG410733J conserved inner membrane protein HHJ35_RS15425 ENOG4105HFZ Membrane HHJ35_RS15430 ENOG4108ZAF Molybdopterin HHJ35_RS15435 ENOG4105M00 molybdopterin converting factor, subunit 1 HHJ35_RS15445 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ35_RS15455 ENOG4105CHW UPF0052 protein HHJ35_RS15465 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ35_RS15470 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HHJ35_RS15485 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HHJ35_RS15490 ENOG4108V1U phospholipid-binding protein HHJ35_RS15495 ENOG4105NBR Pectinesterase HHJ35_RS15500 ENOG4107QM5 aconitate hydratase HHJ35_RS15510 ENOG4105C7F AcnD-accessory protein PrpF HHJ35_RS15515 ENOG4105F04 LysR family Transcriptional regulator HHJ35_RS15525 ENOG4108K4B hydrolase HHJ35_RS15530 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) HHJ35_RS15535 ENOG4105E0C molybdate abc transporter HHJ35_RS15540 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HHJ35_RS15550 ENOG4105F4R Transcriptional regulator mode HHJ35_RS15555 ENOG4105DKW ABC transporter HHJ35_RS15560 ENOG4105CMR udp-glucose 4-epimerase HHJ35_RS15565 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HHJ35_RS15575 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HHJ35_RS15585 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ35_RS15590 ENOG4105JND homeobox protein HHJ35_RS15595 ENOG4105PGM cation diffusion facilitator family transporter HHJ35_RS15600 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HHJ35_RS15655 ENOG4105UFD tol-pal system protein YbgF HHJ35_RS15660 ENOG4105KCK Peptidoglycan-associated lipoprotein HHJ35_RS15670 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HHJ35_RS15680 ENOG4105E02 MotA TolQ exbB proton channel HHJ35_RS15685 ENOG4107YD3 Thioesterase HHJ35_RS15690 ENOG4105KJB cyd operon protein YbgE HHJ35_RS15700 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ35_RS15705 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ35_RS15715 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HHJ35_RS15725 ENOG4105C7S Dehydrogenase HHJ35_RS15730 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HHJ35_RS15735 ENOG4105E33 succinate dehydrogenase HHJ35_RS15740 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ35_RS15745 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HHJ35_RS15750 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HHJ35_RS15760 ENOG4105BZN citrate synthase HHJ35_RS15765 ENOG4108MY7 Fimbrial HHJ35_RS15770 ENOG4108KK1 membrane protein AbrB duplication HHJ35_RS15785 ENOG4107R7A Allophanate hydrolase subunit 2 HHJ35_RS15790 ENOG4105P4J Allophanate hydrolase, subunit 1 HHJ35_RS15795 ENOG4107QNR UPF0135 protein HHJ35_RS15800 ENOG4105DUX Transporter HHJ35_RS15805 ENOG4105CVP deoxyribo-dipyrimidine photolyase HHJ35_RS15810 ENOG4107SEY Conserved Protein HHJ35_RS15815 ENOG4105XIQ Protein of unknown function (DUF2517) HHJ35_RS15840 ENOG4105C08 Histidine kinase HHJ35_RS15845 ENOG4105EEX Two component transcriptional regulator (Winged helix family HHJ35_RS15855 ENOG4105CXN decarboxylase HHJ35_RS15860 ENOG4105D5Q Arginine ornithine antiporter HHJ35_RS15865 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HHJ35_RS15870 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HHJ35_RS15875 ENOG4105EV9 Alpha Beta Hydrolase HHJ35_RS15880 ENOG4105NNH LexA regulated protein HHJ35_RS15885 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HHJ35_RS15895 ENOG41090R7 Ferric uptake HHJ35_RS15900 ENOG4105GX6 (LipO)protein HHJ35_RS15915 ENOG4105MVE transcriptional regulator HHJ35_RS15920 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HHJ35_RS15925 ENOG4107S2N Type III effector Hrp-dependent HHJ35_RS15930 ENOG4108JB8 alcohol dehydrogenase HHJ35_RS15935 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HHJ35_RS15960 ENOG4105CI1 PTS System HHJ35_RS15970 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ35_RS15975 ENOG4105E2R ROK family HHJ35_RS15980 ENOG4105D4U had-superfamily hydrolase, subfamily iia HHJ35_RS15985 ENOG4105CAQ asparagine synthetase HHJ35_RS16025 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ35_RS16035 ENOG4105C9A Phoh family HHJ35_RS16045 ENOG4108JU5 Magnesium and cobalt efflux protein HHJ35_RS16050 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HHJ35_RS16055 ENOG4107U91 Rhomboid family HHJ35_RS16060 ENOG4107RP9 extracellular solute-binding protein, family 3 HHJ35_RS16065 ENOG4105EAD ABC transporter HHJ35_RS16070 ENOG4105DRP amino acid AbC transporter HHJ35_RS16075 ENOG4105CDA abc transporter atp-binding protein HHJ35_RS16085 ENOG4107PAI alpha helical protein HHJ35_RS16100 ENOG4105DJF DNA polymerase III, delta' subunit HHJ35_RS16110 ENOG4108TGR phosphatase HHJ35_RS16115 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HHJ35_RS16125 ENOG4105CJN penicillin-binding protein HHJ35_RS16130 ENOG4105CNI cell division protein FtsW HHJ35_RS16135 ENOG4105K6T rare lipoprotein A HHJ35_RS16140 ENOG4105DZ1 carboxypeptidase HHJ35_RS16160 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HHJ35_RS16185 ENOG4105CEE C4-dicarboxylate transporter HHJ35_RS16190 ENOG4106YYS transcriptional regulatory protein HHJ35_RS16195 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ35_RS16200 ENOG4105DUA (citrate (pro-3S)-lyase ligase HHJ35_RS16210 ENOG4105CI0 Citrate lyase HHJ35_RS16215 ENOG4105CHY citrate lyase, alpha HHJ35_RS16230 ENOG4107QPK )-transporter HHJ35_RS16235 ENOG4105KTS ribonuclease HHJ35_RS16240 ENOG4105NXH GreA GreB family elongation factor HHJ35_RS16245 ENOG4108U51 Universal stress protein HHJ35_RS16250 ENOG4108JU3 Alkyl hydroperoxide reductase HHJ35_RS16255 ENOG4105D3R alkyl hydroperoxide reductase HHJ35_RS16260 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HHJ35_RS16265 ENOG4105DQS Transcriptional regulator HHJ35_RS16270 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HHJ35_RS16275 ENOG4105GTN ParB Domain Protein Nuclease HHJ35_RS16280 ENOG4105CHM Aminotransferase HHJ35_RS16285 ENOG4107SCQ Iron-containing alcohol dehydrogenase HHJ35_RS16290 ENOG4105VCD cytoplasmic protein HHJ35_RS16295 ENOG4105D22 carbon starvation protein HHJ35_RS16300 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HHJ35_RS16305 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HHJ35_RS16310 ENOG4105WQI isochorismatase HHJ35_RS16315 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HHJ35_RS16320 ENOG4105E4F Isochorismate synthase HHJ35_RS16325 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HHJ35_RS16335 ENOG4105DQ5 transport system permease protein HHJ35_RS16340 ENOG4105TVJ transport system, permease HHJ35_RS16345 ENOG4105E0A ABC, transporter HHJ35_RS16350 ENOG4108QY5 Ferric enterobactin transport protein HHJ35_RS16355 ENOG4105C0W non-ribosomal peptide synthetase HHJ35_RS16360 ENOG41085A6 mbth domain-containing protein HHJ35_RS16365 ENOG4105E93 esterase HHJ35_RS16370 ENOG4107RNH Outer membrane receptor FepA HHJ35_RS16375 ENOG4108TSE Transferase HHJ35_RS16390 ENOG4105WQ6 Membrane HHJ35_RS16395 ENOG4105MSB protein, conserved in bacteria HHJ35_RS16400 ENOG4108RCM Nitroreductase HHJ35_RS16405 ENOG4105CUY Mechanosensitive ion channel HHJ35_RS16410 ENOG4105C85 amino acid HHJ35_RS16415 ENOG4108IJF Heavy metal efflux pump, CzcA HHJ35_RS16420 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HHJ35_RS16425 ENOG410624V efflux system protein HHJ35_RS16430 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HHJ35_RS16435 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ35_RS16440 ENOG4105GR3 Histidine kinase HHJ35_RS16445 ENOG410802X bacteriophage n4 adsorption protein b HHJ35_RS16450 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HHJ35_RS16455 ENOG4105QUW HHJ35_RS16460 ENOG4108NC2 Outer membrane protease HHJ35_RS16465 ENOG4108WF3 methyltransferase HHJ35_RS16470 ENOG4105UZW Tail fiber assembly protein HHJ35_RS16490 ENOG4105WQ3 Rna-binding protein HHJ35_RS16495 ENOG4105S2T inner membrane protein YbcI HHJ35_RS16505 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ35_RS16520 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HHJ35_RS16525 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HHJ35_RS16530 ENOG4105C5B carbamate kinase HHJ35_RS16535 ENOG4105G5A Protein of unknown function (DUF2877) HHJ35_RS16540 ENOG4107REC cytoplasmic protein HHJ35_RS16545 ENOG4107R1Q Membrane protein FdrA HHJ35_RS16550 ENOG4105DG4 malate L-lactate dehydrogenase HHJ35_RS16555 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HHJ35_RS16560 ENOG4105S0E allantoin catabolism protein HHJ35_RS16565 ENOG4105BZW Glycerate kinase HHJ35_RS16570 ENOG4105DTE Xanthine uracil vitamin C permease HHJ35_RS16580 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HHJ35_RS16585 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ35_RS16590 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ35_RS16595 ENOG41060W2 glyoxylate carboligase HHJ35_RS16620 ENOG4105CV6 ABC transporter, permease HHJ35_RS16625 ENOG4108I0Y (ABC) transporter HHJ35_RS16630 ENOG4108UJV acyl-CoA thioesterase i HHJ35_RS16635 ENOG4105E1F short-chain dehydrogenase reductase HHJ35_RS16640 ENOG4107QR8 Thioredoxin HHJ35_RS16645 ENOG4105C4B ABC transporter, permease HHJ35_RS16650 ENOG41083J0 (ABC) transporter HHJ35_RS16655 ENOG4107QX8 SPFH domain, Band 7 family protein HHJ35_RS16660 ENOG4105G5H Membrane HHJ35_RS16690 ENOG4107RY6 amino acid HHJ35_RS16695 ENOG4105CSV Glutaminase HHJ35_RS16700 ENOG4105C59 p-type ATPase HHJ35_RS16705 ENOG41081XE plasmid maintenance system antidote protein, xre family HHJ35_RS16710 ENOG41080ET plasmid maintenance system killer protein HHJ35_RS16715 ENOG4105MBR gumn family HHJ35_RS16720 ENOG4108Z66 YbaK ebsC protein HHJ35_RS16735 ENOG4105CGH 5'-nucleotidase HHJ35_RS16740 ENOG4105EU0 Major facilitator Superfamily HHJ35_RS16745 ENOG4105CKD glutathione-regulated potassium-efflux system protein HHJ35_RS16750 ENOG4107RE1 Inosine-guanosine kinase HHJ35_RS16785 ENOG4107QMP dna polymerase iii subunits gamma and tau HHJ35_RS16795 ENOG4105WD1 Membrane HHJ35_RS16800 ENOG4108URS primosomal replication protein n'' HHJ35_RS16805 ENOG4106428 Protein of unknown function (DUF2496) HHJ35_RS16810 ENOG4105EGS Mechanosensitive ion channel HHJ35_RS16815 ENOG4107XI7 Tetr family transcriptional regulator HHJ35_RS16820 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ35_RS16825 ENOG4105BZS acriflavin resistance protein HHJ35_RS16830 ENOG4108UKR Biofilm formation regulator YbaJ HHJ35_RS16835 ENOG4105KF5 hemolysin expression-modulating protein HHJ35_RS16840 ENOG4108UW5 maltose o-acetyltransferase HHJ35_RS16845 ENOG4105GSJ Inner membrane protein ylaC HHJ35_RS16850 ENOG41066DG (EAL) domain protein HHJ35_RS16855 ENOG4105KCV RNA signal recognition particle 4.5S RNA HHJ35_RS16865 ENOG41080UX Methyltransferase HHJ35_RS16870 ENOG4108MNP Glycoprotein polysaccharide metabolism HHJ35_RS16875 ENOG4105C29 acyl-CoA thioesterase HHJ35_RS16880 ENOG4105BZU Histidine kinase HHJ35_RS16885 ENOG4108YZA Nitrogen regulatory protein pii HHJ35_RS16890 ENOG4105BZ1 (ABC) transporter HHJ35_RS16895 ENOG4105BZ1 (ABC) transporter HHJ35_RS16900 ENOG4108XM1 transcriptional regulator AsnC family HHJ35_RS16910 ENOG4108NFA extracellular solute-binding protein HHJ35_RS16920 ENOG4108TGP Thioesterase superfamily protein HHJ35_RS16925 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HHJ35_RS16930 ENOG4105EIN peptidylprolyl cis-trans isomerase HHJ35_RS16935 ENOG4105K70 DNA-binding protein HHJ35_RS16940 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HHJ35_RS16960 ENOG4105M85 Bola protein HHJ35_RS16965 ENOG4105IEY (LipO)protein HHJ35_RS16970 ENOG4105EYM Major Facilitator superfamily HHJ35_RS16975 ENOG4105E2S oxidase) subunit II HHJ35_RS16980 ENOG4105BZ9 Cytochrome C oxidase, subunit I HHJ35_RS16985 ENOG4105CCU oxidase (Subunit III) HHJ35_RS16990 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HHJ35_RS17000 ENOG4107RDB Major Facilitator HHJ35_RS17010 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HHJ35_RS17015 ENOG4107S0N DJ-1 family HHJ35_RS17030 ENOG4105CTB Polyprenyl synthetase HHJ35_RS17040 ENOG4105CPC Aldo Keto reductase HHJ35_RS17045 ENOG4108ZAI phosphatidylglycerophosphatase a HHJ35_RS17050 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HHJ35_RS17065 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HHJ35_RS17075 ENOG4108KIC (LipO)protein HHJ35_RS17080 ENOG4105DRB nucleoside-specific channel-forming protein HHJ35_RS17085 ENOG4105N1F Hnh endonuclease HHJ35_RS17090 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ35_RS17095 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ35_RS17100 ENOG4105VIE preprotein translocase, subunit YajC HHJ35_RS17120 ENOG4107R28 alpha amylase, catalytic region HHJ35_RS17125 ENOG4105C85 amino acid HHJ35_RS17130 ENOG4105CWM branched-chain amino acid transport system II carrier protein HHJ35_RS17135 ENOG4105BZU Histidine kinase HHJ35_RS17140 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ35_RS17145 ENOG4107RH8 nuclease SbcCD subunit D HHJ35_RS17150 ENOG4105EYH Exonuclease HHJ35_RS17155 ENOG4105F27 Major Facilitator HHJ35_RS17160 ENOG4105DKQ ROK family HHJ35_RS17185 ENOG4105HBA AroM protein HHJ35_RS17190 ENOG4105SS3 HHJ35_RS17205 ENOG4105II7 pyrroline-5-carboxylate reductase HHJ35_RS17210 ENOG4105BZU Histidine kinase HHJ35_RS17215 ENOG4105VIF phosphate starvation-inducible protein HHJ35_RS17220 ENOG4105G6Z alkaline phosphatase HHJ35_RS17235 ENOG4105CPF Cell wall formation (By similarity) HHJ35_RS17240 ENOG4105UNH Membrane HHJ35_RS17245 ENOG4105FR5 inner membrane protein YaiY HHJ35_RS17250 ENOG4107QS8 (LipO)protein HHJ35_RS17255 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HHJ35_RS17260 ENOG4107R6D beta-lactam binding protein AmpH HHJ35_RS17265 ENOG4108PNB DNA-binding transcriptional regulator HHJ35_RS17275 ENOG4105D52 delta-aminolevulinic acid dehydratase HHJ35_RS17280 ENOG4105E2B Taurine dioxygenase HHJ35_RS17285 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HHJ35_RS17290 ENOG4108IY8 ABC, transporter HHJ35_RS17295 ENOG4106FTQ Taurine ABC transporter, periplasmic HHJ35_RS17300 ENOG4107W19 lmbE family HHJ35_RS17305 ENOG4108PBI Polysaccharide metabolism HHJ35_RS17315 ENOG4105SRB Uncharacterized protein yaiO HHJ35_RS17335 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HHJ35_RS17345 ENOG4105ETE Transcriptional regulator (LacI family HHJ35_RS17355 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HHJ35_RS17360 ENOG4108UW5 maltose o-acetyltransferase HHJ35_RS17365 ENOG4105DZC cytosine deaminase HHJ35_RS17370 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HHJ35_RS17375 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ35_RS17380 ENOG4105DXD 2-methylcitrate dehydratase HHJ35_RS17385 ENOG4105BZN citrate synthase HHJ35_RS17390 ENOG4105CR4 methylisocitrate lyase HHJ35_RS17400 ENOG4105TDT uncharacterized protein yahO HHJ35_RS17405 ENOG4105E82 cytochrome subunit of dehydrogenase HHJ35_RS17415 ENOG4105DQ4 alcohol dehydrogenase HHJ35_RS17420 ENOG4105CNN ABC, transporter HHJ35_RS17425 ENOG4105CNN ABC, transporter HHJ35_RS17430 ENOG4105C2J ABC transporter HHJ35_RS17435 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ35_RS17445 ENOG4105DZC cytosine deaminase HHJ35_RS17450 ENOG4105C5B carbamate kinase HHJ35_RS17455 ENOG4107REC cytoplasmic protein HHJ35_RS17460 ENOG4107R1Q Membrane protein FdrA HHJ35_RS17465 ENOG4105N16 Protein of unknown function (DUF2877) HHJ35_RS17470 ENOG4107SNB ankyrin repeat protein YahD HHJ35_RS17475 ENOG4105SZ2 membrAne HHJ35_RS17480 ENOG4108NUU Transcriptional regulator HHJ35_RS17485 ENOG4105BZU Histidine kinase HHJ35_RS17490 ENOG4105C94 Transporter HHJ35_RS17510 ENOG4108W9T type 1 fimbriae regulatory protein HHJ35_RS17515 ENOG4105BZU Histidine kinase HHJ35_RS17540 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HHJ35_RS17545 ENOG4107QR9 Iron-sulfur cluster binding protein HHJ35_RS17550 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ35_RS17555 ENOG4108K01 transcriptional regulator HHJ35_RS17560 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ35_RS17565 ENOG41066GK UPF0379 protein ykgI HHJ35_RS17570 ENOG4108KBJ Inner membrane protein YkgB HHJ35_RS17575 ENOG4105CV8 reductase HHJ35_RS17595 ENOG4107SET aldo keto reductase HHJ35_RS17600 ENOG4105EQ2 LysR family Transcriptional regulator HHJ35_RS17605 ENOG410642W LysR family Transcriptional regulator HHJ35_RS17615 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ35_RS17670 ENOG4105PI0 Ferredoxin HHJ35_RS17680 ENOG4105R3P Inner membrane protein yagU HHJ35_RS17730 ENOG4105FCK Membrane HHJ35_RS17750 ENOG4105CIN aminoacyl-histidine dipeptidase HHJ35_RS17755 ENOG4108S2Y peptide Chain Release factor HHJ35_RS17765 ENOG4108HYG acetyltransferase HHJ35_RS17770 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome HHJ35_RS17775 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system HHJ35_RS17800 ENOG4108UK5 Transposase HHJ35_RS17805 ENOG4108YS0 lipoprotein YafL HHJ35_RS17810 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HHJ35_RS17815 ENOG4105E7A Glutamine amidotransferase HHJ35_RS17825 ENOG4107QPN acyl-Coa dehydrogenase HHJ35_RS17830 ENOG4108WN0 inhibitor of vertebrate lysozyme HHJ35_RS17835 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ35_RS17875 ENOG4105CS6 Rhs element vgr protein HHJ35_RS17880 ENOG4108WC9 type VI secretion system effector, hcp1 family HHJ35_RS17930 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ35_RS17960 ENOG410600K aminopeptidase HHJ35_RS17970 ENOG4107RZZ dna polymerase iii epsilon subunit HHJ35_RS17980 ENOG4105D1A Methyltransferase HHJ35_RS17990 ENOG4105E9H Lytic Murein transglycosylase HHJ35_RS17995 ENOG4105F2W methyltransferase HHJ35_RS18005 ENOG4105HEI LysR family (Transcriptional regulator HHJ35_RS18010 ENOG4105CV8 reductase HHJ35_RS18045 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HHJ35_RS18050 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HHJ35_RS18055 ENOG4108UMI ABC transporter, permease HHJ35_RS18060 ENOG4105D01 (LipO)protein HHJ35_RS18065 ENOG4108R8X outer membrane lipoprotein HHJ35_RS18070 ENOG4108R96 Methyltransferase, YaeB family HHJ35_RS18080 ENOG4108UY0 (LipO)protein HHJ35_RS18085 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HHJ35_RS18090 ENOG4108YZN class I peptide chain release factor HHJ35_RS18095 ENOG4108VWS Yaeq family HHJ35_RS18105 ENOG4105M1T rho-binding antiterminator HHJ35_RS18110 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HHJ35_RS18115 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HHJ35_RS18120 ENOG4105CXN decarboxylase HHJ35_RS18130 ENOG4105C0B DNA polymerase III (alpha subunit) HHJ35_RS18160 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HHJ35_RS18170 ENOG4105DZP Membrane-associated zinc metalloprotease HHJ35_RS18175 ENOG4105KNE Phosphatidate cytidylyltransferase HHJ35_RS18180 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HHJ35_RS18185 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HHJ35_RS18210 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HHJ35_RS18230 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HHJ35_RS18235 ENOG4105C0H protease HHJ35_RS18250 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HHJ35_RS18255 ENOG4105EN6 Membrane HHJ35_RS18280 ENOG4105S6R Iron-hydroxamate transporter permease subunit HHJ35_RS18285 ENOG4105J76 Periplasmic binding protein HHJ35_RS18290 ENOG4105E0A ABC, transporter HHJ35_RS18295 ENOG4105E0K tonB-dependent siderophore receptor HHJ35_RS18300 ENOG4105BZ4 penicillin-binding protein HHJ35_RS18305 ENOG4105CQ7 ATP-dependent helicase HHJ35_RS18310 ENOG4107XID 2'-5' rna ligase HHJ35_RS18325 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) HHJ35_RS18330 ENOG4105DJ0 Poly(A) Polymerase HHJ35_RS18335 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HHJ35_RS18345 ENOG4108VEV chaperone HHJ35_RS18350 ENOG4105CW0 outer membrane usher protein HHJ35_RS18355 ENOG4108XEY fimbrial-like adhesin protein HHJ35_RS18360 ENOG4105SYG Fimbrial protein HHJ35_RS18365 ENOG4105SN2 fimbrial-like adhesin protein HHJ35_RS18370 ENOG4105P0Q fimbrial-like protein YadC HHJ35_RS18385 ENOG4108A32 Transposase HHJ35_RS18395 ENOG4107BJW polysaccharide deacetylase HHJ35_RS18400 ENOG4108YTN IIa component HHJ35_RS18405 ENOG4105E3A (ABC) transporter HHJ35_RS18410 ENOG4105DA5 (ABC) transporter HHJ35_RS18415 ENOG41077A9 carbonic anhydrase HHJ35_RS18420 ENOG4108UGV hypoxanthine phosphoribosyltransferase HHJ35_RS18425 ENOG4105DZG Dehydrogenase HHJ35_RS18430 ENOG4105E3B Multicopper oxidase HHJ35_RS18435 ENOG4108ZRK uncharacterized protein yacC HHJ35_RS18455 ENOG4107QIJ Aconitate hydratase 2 HHJ35_RS18460 ENOG4108NST exported protein HHJ35_RS18465 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ35_RS18470 ENOG4107QSN dihydrolipoamide acetyltransferase HHJ35_RS18475 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HHJ35_RS18480 ENOG41073TP transcriptional regulator HHJ35_RS18495 ENOG41060S4 immunity protein HHJ35_RS18510 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ35_RS18515 ENOG4105C85 amino acid HHJ35_RS18520 ENOG4106A72 regulatory protein AmpE HHJ35_RS18525 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ35_RS18530 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HHJ35_RS18535 ENOG4108ZUW Major pilin subunit HHJ35_RS18540 ENOG4107QHF type ii secretion system protein e HHJ35_RS18545 ENOG4105D7Q type ii secretion system HHJ35_RS18555 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HHJ35_RS18570 ENOG4105M6F mutator MutT protein HHJ35_RS18590 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HHJ35_RS18595 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HHJ35_RS18600 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HHJ35_RS18605 ENOG4105CPF Cell wall formation (By similarity) HHJ35_RS18620 ENOG4105CNI cell division protein FtsW HHJ35_RS18625 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) HHJ35_RS18635 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HHJ35_RS18640 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HHJ35_RS18645 ENOG4105CJN penicillin-binding protein HHJ35_RS18650 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HHJ35_RS18665 ENOG4107B7Y DNA-binding transcriptional regulator FruR HHJ35_RS18675 ENOG4108ZP8 Acetolactate synthase small subunit HHJ35_RS18680 ENOG4105C7K acetolactate synthase HHJ35_RS18685 ENOG41064T2 transcriptional regulator, lysR family HHJ35_RS18725 ENOG4105DP9 ABC transporter HHJ35_RS18730 ENOG4106SMU thiamine transporter membrane protein HHJ35_RS18740 ENOG4108KF1 Membrane HHJ35_RS18755 ENOG41063TF transcriptional regulator (AraC HHJ35_RS18770 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ35_RS18775 ENOG4105CQ2 DNA polymerase HHJ35_RS18780 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HHJ35_RS18785 ENOG4105D3G Pseudouridine synthase HHJ35_RS18790 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HHJ35_RS18800 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HHJ35_RS18805 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HHJ35_RS18840 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HHJ35_RS18855 ENOG4105C54 Major Facilitator superfamily HHJ35_RS18860 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HHJ35_RS18865 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ35_RS18900 ENOG4106YT9 Enoyl-CoA hydratase HHJ35_RS18910 ENOG4108XNW Transcriptional activatory protein CaiF HHJ35_RS18915 ENOG4108RS6 transposase HHJ35_RS18920 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HHJ35_RS18925 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HHJ35_RS18950 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HHJ35_RS18965 ENOG4105DTN riboflavin biosynthesis protein ribF HHJ35_RS18970 ENOG410647N response to DNA damage stimulus HHJ35_RS18980 ENOG41063Z6 transcriptional regulator, lysR family HHJ35_RS18995 ENOG41061MV Arylsulfatase HHJ35_RS19005 ENOG4105WI6 cell killing protein encoded within cryptic prophage HHJ35_RS19025 ENOG4108QUJ UPF0174 protein YaaW HHJ35_RS19030 ENOG4106HK8 GPR1 FUN34 yaaH family protein HHJ35_RS19035 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ35_RS19045 ENOG4105BZG amino acid carrier protein HHJ35_RS19050 ENOG4105D1Q UPF0246 protein HHJ35_RS19055 ENOG41062C6 Protein of unknown function (DUF2502) HHJ35_RS19060 ENOG4105D98 threonine synthase HHJ35_RS19070 ENOG4105CFH Aspartokinase HHJ35_RS19080 ENOG4106FVC RNA methyltransferase HHJ35_RS19085 ENOG410759A HHJ35_RS19090 ENOG41065U4 response regulator HHJ35_RS19095 ENOG4105CT7 inner membrane cred family protein HHJ35_RS19100 ENOG4105EB3 Histidine kinase HHJ35_RS19105 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ35_RS19110 ENOG4108RH0 Crea protein HHJ35_RS19115 ENOG4105UEI Transcriptional Regulator AraC Family HHJ35_RS19125 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ35_RS19135 ENOG4107SC1 transglycosylase HHJ35_RS19140 ENOG4105C5H ABC transporter HHJ35_RS19145 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HHJ35_RS19150 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HHJ35_RS19155 ENOG4105EAC phosphoserine phosphatase HHJ35_RS19160 ENOG41062Z9 Membrane HHJ35_RS19165 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) HHJ35_RS19175 ENOG4105D3A purine nucleoside phosphorylase DeoD-type HHJ35_RS19195 ENOG4105G0K glycine radical enzyme YjjI family HHJ35_RS19200 ENOG41076CZ activating enzyme HHJ35_RS19205 ENOG4105EYA deoxyribonuclease HHJ35_RS19210 ENOG4108NRW Phospholipase, patatin family HHJ35_RS19220 ENOG4105K3G Periplasmic Protein HHJ35_RS19230 ENOG4105PAD Hydrolase HHJ35_RS19235 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HHJ35_RS19240 ENOG4108WPU DNA polymerase III subunit psi HHJ35_RS19265 ENOG4105YBH Protein of unknown function (DUF1435) HHJ35_RS19270 ENOG4108819 ferric iron reductase HHJ35_RS19275 ENOG4108T94 DNA-binding transcriptional activator BglJ HHJ35_RS19280 ENOG4108N8T regulatoR HHJ35_RS19285 ENOG4105DWK Membrane HHJ35_RS19300 ENOG4106CVF DNA replication protein HHJ35_RS19305 ENOG4105RI1 glycoprotein receptor HHJ35_RS19315 ENOG4105CPQ Dehydrogenase HHJ35_RS19320 ENOG410617M Transcriptional regulator HHJ35_RS19330 ENOG4105C8Q Methyl-accepting chemotaxis HHJ35_RS19335 ENOG4105D22 carbon starvation protein HHJ35_RS19340 ENOG4105VCD cytoplasmic protein HHJ35_RS19345 ENOG4105CKI cobalamin synthesis protein HHJ35_RS19370 ENOG41083G8 Multidrug resistance protein MdtM HHJ35_RS19390 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HHJ35_RS19395 ENOG4105CIZ coA-substrate-specific enzyme activase HHJ35_RS19410 ENOG4105CBP Major Facilitator HHJ35_RS19420 ENOG41074DU domain protein HHJ35_RS19425 ENOG4108P2H Inner membrane protein YjiG HHJ35_RS19430 ENOG4105DYB Isoaspartyl dipeptidase HHJ35_RS19435 ENOG4107YNJ LysR family Transcriptional regulator HHJ35_RS19460 ENOG4105C6F GntR Family Transcriptional Regulator HHJ35_RS19465 ENOG4105DEI Mannitol dehydrogenase HHJ35_RS19475 ENOG4107EFN gluconate transport system permease 3 HHJ35_RS19480 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HHJ35_RS19485 ENOG4108T65 Fimbrial HHJ35_RS19490 ENOG4108SQA Fimbrial HHJ35_RS19495 ENOG4105CW0 outer membrane usher protein HHJ35_RS19500 ENOG4108NAE Fimbrial chaperone protein HHJ35_RS19505 ENOG4108S54 Fimbrial protein HHJ35_RS19515 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off HHJ35_RS19520 ENOG4108W9T type 1 fimbriae regulatory protein HHJ35_RS19525 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria HHJ35_RS19530 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) HHJ35_RS19555 ENOG41080VW acetyltransferase HHJ35_RS19560 ENOG4105DTA methyltransferase HHJ35_RS19570 ENOG4105CN9 Peptidase m42 family protein HHJ35_RS19575 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ35_RS19580 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ35_RS19585 ENOG4106P19 photosystem i assembly btpa HHJ35_RS19590 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ35_RS19595 ENOG4108RK0 3-epimerase HHJ35_RS19600 ENOG4108PQ7 sgc region transcriptional regulator HHJ35_RS19605 ENOG4106P37 HTH-type transcriptional regulator YjhI HHJ35_RS19610 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HHJ35_RS19615 ENOG4105C01 Dihydroxy-acid dehydratase HHJ35_RS19620 ENOG4105C6Z Gluconate HHJ35_RS19625 ENOG4105DKT Transcriptional regulator HHJ35_RS19635 ENOG4107W7X Aldolase HHJ35_RS19645 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) HHJ35_RS19650 ENOG4108SHN Glycosyl transferase, family 2 HHJ35_RS19655 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 HHJ35_RS19715 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ35_RS19725 ENOG4108YGG dna repair protein HHJ35_RS19730 ENOG4106549 Antirestriction protein HHJ35_RS19735 ENOG4106H6R UPF0380 protein HHJ35_RS19745 ENOG4105F4K antigen 43 HHJ35_RS19795 ENOG4108YXQ IS66 Orf2 family protein HHJ35_RS19800 ENOG4105E5H Transposase HHJ35_RS19820 ENOG4107FB0 transcriptional regulator DeoR family HHJ35_RS19845 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HHJ35_RS19855 ENOG4106ETB IIa component HHJ35_RS19880 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) HHJ35_RS19885 ENOG4105CI1 PTS System HHJ35_RS19890 ENOG4105QEK Transcriptional regulator HHJ35_RS19905 ENOG4107R3N Filamentation induced by cAMP protein fic HHJ35_RS19935 ENOG4105EB3 Histidine kinase HHJ35_RS19975 ENOG4105DQ4 alcohol dehydrogenase HHJ35_RS19980 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HHJ35_RS19985 ENOG4105CPQ Dehydrogenase HHJ35_RS19990 ENOG4105CHR reductase HHJ35_RS19995 ENOG4105C6Z Gluconate HHJ35_RS20000 ENOG4105K2J Transcriptional regulator HHJ35_RS20005 ENOG4105D7A ATP-binding protein HHJ35_RS20010 ENOG4108K5H permease YjgP YjgQ family protein HHJ35_RS20015 ENOG4108M8S permease YjgP YjgQ family protein HHJ35_RS20025 ENOG4105MYG DNA polymerase iii, chi subunit HHJ35_RS20030 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HHJ35_RS20035 ENOG4108M3P Membrane HHJ35_RS20040 ENOG4108MJ3 acetyltransferase HHJ35_RS20045 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HHJ35_RS20050 ENOG4105DBV ornithine carbamoyltransferase HHJ35_RS20055 ENOG4105XEP YhcH YjgK YiaL family protein HHJ35_RS20070 ENOG4105DBV ornithine carbamoyltransferase HHJ35_RS20075 ENOG4105CSX c4-dicarboxylate anaerobic carrier HHJ35_RS20085 ENOG4107C93 pyrBI operon leader peptide HHJ35_RS20100 ENOG4105KME endoribonuclease L-psp HHJ35_RS20105 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HHJ35_RS20115 ENOG4105D4X repressor HHJ35_RS20120 ENOG4105C5Y PTS System HHJ35_RS20125 ENOG4105CG3 alpha amylase, catalytic region HHJ35_RS20130 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HHJ35_RS20135 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HHJ35_RS20140 ENOG4108XVM Cytochrome b(562) HHJ35_RS20145 ENOG4105CMS peptidase U62, modulator of DNA gyrase HHJ35_RS20155 ENOG4105DFU Cell wall formation (By similarity) HHJ35_RS20165 ENOG41062B0 ABC transporter, permease HHJ35_RS20170 ENOG4107R9N ABC transporter HHJ35_RS20175 ENOG4105C2J ABC transporter HHJ35_RS20180 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HHJ35_RS20185 ENOG4105F0N pyrophosphate phospho-hydrolase HHJ35_RS20190 ENOG4108ZHD aig2 family HHJ35_RS20195 ENOG4105MA0 exported protein HHJ35_RS20200 ENOG4105CFU surface antigen HHJ35_RS20210 ENOG4105C37 (CBS) domain HHJ35_RS20215 ENOG41061GZ Protein of unknown function (DUF1107) HHJ35_RS20220 ENOG4108UUE Transcriptional regulator HHJ35_RS20225 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HHJ35_RS20230 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HHJ35_RS20235 ENOG4105KVH Transcriptional regulator HHJ35_RS20240 ENOG4105ECR NmrA family HHJ35_RS20245 ENOG4105DXC membrane HHJ35_RS20260 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ35_RS20265 ENOG4105FHY Opacity-associated protein A HHJ35_RS20275 ENOG4105CHR reductase HHJ35_RS20285 ENOG4105E39 Enoyl-CoA hydratase HHJ35_RS20290 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ35_RS20295 ENOG4107S3R L-aspartate oxidase HHJ35_RS20300 ENOG4105DPW Major facilitator superfamily MFS_1 HHJ35_RS20320 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HHJ35_RS20335 ENOG4105KIT UPF0379 protein yjfY HHJ35_RS20350 ENOG4105H6Q decarboxylase HHJ35_RS20360 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport HHJ35_RS20365 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HHJ35_RS20380 ENOG4108MXZ Esterase HHJ35_RS20385 ENOG4105WSB biofilm stress and motility protein A HHJ35_RS20390 ENOG4105S17 UPF0379 protein yjfN HHJ35_RS20395 ENOG4105CSU acyl-Coa dehydrogenase HHJ35_RS20400 ENOG4106032 Glutathionylspermidine synthase HHJ35_RS20405 ENOG4108KXT Conserved Protein HHJ35_RS20410 ENOG4105Z6B inner membrane protein yjfl HHJ35_RS20415 ENOG4107VNS Protein of unknown function (DUF2491) HHJ35_RS20420 ENOG4108P9J Phage shock protein A HHJ35_RS20425 ENOG4105FUX Conserved Protein HHJ35_RS20430 ENOG4105C2N RNA methyltransferase TrmH family group 3 HHJ35_RS20435 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HHJ35_RS20455 ENOG4105EPW hflc protein HHJ35_RS20460 ENOG4107QJR hflk protein HHJ35_RS20465 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HHJ35_RS20485 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ35_RS20490 ENOG4105K8N protein family UPF0079, ATPase HHJ35_RS20495 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HHJ35_RS20500 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HHJ35_RS20540 ENOG4105EGS Mechanosensitive ion channel HHJ35_RS20545 ENOG4106CG8 Inner membrane protein YjeO HHJ35_RS20550 ENOG4106V5W HHJ35_RS20555 ENOG4107SC7 Inner membrane transporter yjeM HHJ35_RS20565 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ35_RS20570 ENOG4105E33 succinate dehydrogenase HHJ35_RS20585 ENOG41066YJ Beta-lactamase HHJ35_RS20590 ENOG4105QNF Outer membrane lipoprotein HHJ35_RS20595 ENOG4105KPY Small multidrug resistance protein HHJ35_RS20600 ENOG4106BSU Entericidin B HHJ35_RS20605 ENOG4107PEH Entericidin EcnA/B family HHJ35_RS20615 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HHJ35_RS20620 ENOG4105MTB Uncharacterized protein YjeJ HHJ35_RS20625 ENOG4108ZVF (LipO)protein HHJ35_RS20640 ENOG4105DVH amino acid HHJ35_RS20645 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HHJ35_RS20650 ENOG4108IJ0 Aspartate ammonia-lyase HHJ35_RS20655 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ35_RS20665 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) HHJ35_RS20670 ENOG4108SIC Transcriptional regulator HHJ35_RS20700 ENOG41067TZ transcriptional regulator, MarR family HHJ35_RS20710 ENOG4105D5Q Arginine ornithine antiporter HHJ35_RS20715 ENOG4105CXN decarboxylase HHJ35_RS20720 ENOG4105D5Q Arginine ornithine antiporter HHJ35_RS20730 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HHJ35_RS20785 ENOG4105D5K Hemolysin activator protein HHJ35_RS20810 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) HHJ35_RS20815 ENOG4107RWI ethanolamine utilization protein eutJ HHJ35_RS20825 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HHJ35_RS20840 ENOG4105KNY Microcompartments protein HHJ35_RS20845 ENOG4105EHR propanediol utilization protein pduB HHJ35_RS20850 ENOG4108EKI Dehydrogenase HHJ35_RS20860 ENOG4107R7Y intracellular protease Pfpi family HHJ35_RS20870 ENOG4105F1A Pyruvate formate-lyase HHJ35_RS20885 ENOG4105EKQ RNA-directed DNA polymerase HHJ35_RS20890 ENOG4105C2F Histidine kinase HHJ35_RS20895 ENOG4106R3P AraC family transcriptional regulator HHJ35_RS20905 ENOG4105KNY Microcompartments protein HHJ35_RS20955 ENOG4105TS0 gtp-binding protein HHJ35_RS20960 ENOG4108KZE transcriptional regulator HHJ35_RS20975 ENOG4106H6R UPF0380 protein HHJ35_RS20980 ENOG4106549 Antirestriction protein HHJ35_RS20985 ENOG4108YGG dna repair protein HHJ35_RS20995 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ35_RS21020 ENOG4108M3R transcriptional activator CadC HHJ35_RS21025 ENOG4105D5Q Arginine ornithine antiporter HHJ35_RS21030 ENOG4105CXN decarboxylase HHJ35_RS21035 ENOG4105DUX Transporter HHJ35_RS21040 ENOG4105CRK lysyL-tRNA synthetase HHJ35_RS21055 ENOG410830R acetyltransferase HHJ35_RS21060 ENOG4105VR1 Pfam:DUF1271 HHJ35_RS21065 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ35_RS21070 ENOG4108MRH transcriptional regulatory protein HHJ35_RS21075 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ35_RS21080 ENOG4107GFK fumarate HHJ35_RS21085 ENOG4108R5S membrane HHJ35_RS21090 ENOG4105F8D glycoside hydrolase family 4 HHJ35_RS21095 ENOG4108K2B transcriptional regulator HHJ35_RS21100 ENOG4105CXN decarboxylase HHJ35_RS21105 ENOG4106ZGR Transcriptional regulator HHJ35_RS21110 ENOG4105D5Q Arginine ornithine antiporter HHJ35_RS21115 ENOG4105DIJ Phosphoethanolamine transferase HHJ35_RS21120 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ35_RS21125 ENOG4105ECM Sensor protein basS pmrB HHJ35_RS21135 ENOG4105CSH Transporter HHJ35_RS21140 ENOG4108YIV HHJ35_RS21145 ENOG4108F5E vimentin HHJ35_RS21150 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HHJ35_RS21155 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HHJ35_RS21165 ENOG4105EHI Phosphonate ABC transporter, periplasmic HHJ35_RS21175 ENOG4107RJJ Transcriptional regulator HHJ35_RS21180 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HHJ35_RS21185 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HHJ35_RS21190 ENOG4105EKV Phosphonate metabolism protein HHJ35_RS21195 ENOG4105FT8 Phosphonate metabolism HHJ35_RS21200 ENOG4105ENV phosphonate C-P lyase system protein PhnK HHJ35_RS21205 ENOG4105HRV phosphonate c-p lyase system protein phnl HHJ35_RS21210 ENOG4105FD8 phosphonate metabolism protein PhnM HHJ35_RS21220 ENOG410849A acetyltransferase, (GNAT) family HHJ35_RS21225 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HHJ35_RS21235 ENOG4108YZG isomerase HHJ35_RS21240 ENOG4105NYY transcriptional regulator, RpiR HHJ35_RS21245 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ35_RS21250 ENOG4105C2J ABC transporter HHJ35_RS21260 ENOG4105UP7 3-epimerase HHJ35_RS21265 ENOG4107TFG D-allose kinase HHJ35_RS21270 ENOG4105EUZ Beta-lactamase domain protein HHJ35_RS21280 ENOG4105J12 Multidrug resistance protein mdtN HHJ35_RS21285 ENOG4108MI0 Resistance protein HHJ35_RS21290 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ35_RS21305 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ35_RS21310 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ35_RS21315 ENOG4105C3U ABC transporter HHJ35_RS21320 ENOG4108JQ7 (ABC) transporter HHJ35_RS21325 ENOG41082ND Uncharacterized protein yjcO HHJ35_RS21330 ENOG4105CK2 sodium dicarboxylate symporter HHJ35_RS21335 ENOG4108W0S formate-dependent nitrite reductase complex HHJ35_RS21345 ENOG4108QKW cytochrome c-type biogenesis protein HHJ35_RS21350 ENOG4105DVI reductase, NrfD HHJ35_RS21355 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ35_RS21360 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HHJ35_RS21370 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ35_RS21375 ENOG41062QD Membrane HHJ35_RS21385 ENOG41067MG lrgb family HHJ35_RS21395 ENOG4105CMU LysR family (Transcriptional regulator HHJ35_RS21400 ENOG4105EEQ Na H antiporter HHJ35_RS21405 ENOG4105C7N Xanthine uracil vitamin C permease HHJ35_RS21410 ENOG4108Z4X TRANSCRIPTIONal HHJ35_RS21415 ENOG4108W3Q Transcriptional regulator HHJ35_RS21420 ENOG4108M8H domain protein HHJ35_RS21425 ENOG4105PMV Membrane HHJ35_RS21430 ENOG4108UUM single-stranded DNA-binding protein HHJ35_RS21435 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HHJ35_RS21440 ENOG4105MSB protein, conserved in bacteria HHJ35_RS21445 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HHJ35_RS21450 ENOG4105F0S class B acid phosphatase HHJ35_RS21455 ENOG4105CQZ Histidine kinase HHJ35_RS21460 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ35_RS21465 ENOG4105DG4 malate L-lactate dehydrogenase HHJ35_RS21470 ENOG4107QPK )-transporter HHJ35_RS21475 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HHJ35_RS21480 ENOG4105CMV Succinyl-CoA synthetase subunit beta HHJ35_RS21485 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ35_RS21490 ENOG4105C7S Dehydrogenase HHJ35_RS21495 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HHJ35_RS21500 ENOG4105CGF Aromatic amino acid aminotransferase HHJ35_RS21505 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HHJ35_RS21510 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HHJ35_RS21515 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ35_RS21520 ENOG4105CDU Replicative dna helicase HHJ35_RS21525 ENOG4105ETE Transcriptional regulator (LacI family HHJ35_RS21530 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ35_RS21535 ENOG4106YT9 Enoyl-CoA hydratase HHJ35_RS21545 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ35_RS21550 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HHJ35_RS21555 ENOG4105P4Z Phage shock protein G HHJ35_RS21560 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ35_RS21565 ENOG4105MYN Zinc uptake regulation protein HHJ35_RS21570 ENOG4105VDW Csbd family HHJ35_RS21575 ENOG4107R73 Mate efflux family protein HHJ35_RS21585 ENOG41080IJ Diacylglycerol kinase HHJ35_RS21605 ENOG4107W52 maltose operon periplasmic protein HHJ35_RS21615 ENOG4108IJ9 (ABC) transporter HHJ35_RS21620 ENOG4107FKK extracellular solute-binding protein family 1 HHJ35_RS21625 ENOG4105D56 permease protein HHJ35_RS21630 ENOG4105EG2 ABC transporter, permease HHJ35_RS21645 ENOG4105E3R (LipO)protein HHJ35_RS21650 ENOG4108Q9C Periplasmic Protein HHJ35_RS21655 ENOG4108MDC (LipO)protein HHJ35_RS21670 ENOG4105CFH Aspartokinase HHJ35_RS21675 ENOG4108ZR5 Conserved Protein HHJ35_RS21680 ENOG4105FE9 pseudouridine synthase HHJ35_RS21685 ENOG4105DKT Transcriptional regulator HHJ35_RS21690 ENOG4105CHR reductase HHJ35_RS21695 ENOG4108XCU pts system HHJ35_RS21700 ENOG4105KPI PTS system sorbose subfamily IIB component HHJ35_RS21705 ENOG4105ETZ PTS System HHJ35_RS21710 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ35_RS21715 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HHJ35_RS21725 ENOG4105EAM Na Pi-cotransporter HHJ35_RS21740 ENOG4105C3R Methionine synthase HHJ35_RS21745 ENOG41069M3 Transcriptional regulator HHJ35_RS21755 ENOG4108I9X Isocitrate lyase HHJ35_RS21760 ENOG4107QP3 malate synthase g HHJ35_RS21770 ENOG4105K5X acetyltransferase HHJ35_RS21775 ENOG41062WK cellular response to acidity HHJ35_RS21805 ENOG4105C12 Phosphoribosylglycinamide synthetase HHJ35_RS21810 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ35_RS21815 ENOG4105BZU Histidine kinase HHJ35_RS21820 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HHJ35_RS21825 ENOG4108T8B Protein of unknown function (DUF1481) HHJ35_RS21835 ENOG4105R2J Conserved Protein HHJ35_RS21870 ENOG4105D06 uba thif-type nad fad binding protein HHJ35_RS21875 ENOG4105WHD thiamine biosynthesis protein ThiS HHJ35_RS21885 ENOG4105D41 biosynthesis protein thiH HHJ35_RS21920 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HHJ35_RS21925 ENOG4105PM1 preprotein translocase subunit SecE HHJ35_RS21960 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HHJ35_RS21965 ENOG4105D4A Cell wall formation (By similarity) HHJ35_RS22005 ENOG4108Y73 Membrane HHJ35_RS22020 ENOG4105CH2 amidohydrolase HHJ35_RS22030 ENOG4105C5Q Transcriptional regulator HHJ35_RS22035 ENOG4108I5G Major Facilitator superfamily HHJ35_RS22040 ENOG4105CXK mandelate racemase muconate lactonizing HHJ35_RS22055 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HHJ35_RS22070 ENOG4105DIJ Phosphoethanolamine transferase HHJ35_RS22075 ENOG4106R3P AraC family transcriptional regulator HHJ35_RS22080 ENOG4108XCZ PTS System HHJ35_RS22085 ENOG4108AHH pyruvate formate lyase II activase HHJ35_RS22095 ENOG4108YRF PTS System HHJ35_RS22100 ENOG4105DM4 PTS System HHJ35_RS22105 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ35_RS22110 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ35_RS22115 ENOG4105DCT glycerol dehydrogenase HHJ35_RS22120 ENOG4108XC3 NADH ubiquinone oxidoreductase HHJ35_RS22125 ENOG4108Q5Y Membrane HHJ35_RS22135 ENOG4105SYT Methylenetetrahydrofolate reductase HHJ35_RS22140 ENOG4105CGH 5'-nucleotidase HHJ35_RS22150 ENOG4105CGH 5'-nucleotidase HHJ35_RS22155 ENOG4105CGH 5'-nucleotidase HHJ35_RS22160 ENOG4105DRB nucleoside-specific channel-forming protein HHJ35_RS22165 ENOG4105CFH Aspartokinase HHJ35_RS22170 ENOG4105C28 cystathionine HHJ35_RS22180 ENOG4107S01 Repressor protein MetJ HHJ35_RS22190 ENOG4105C25 Primosomal protein n' HHJ35_RS22195 ENOG4105ETE Transcriptional regulator (LacI family HHJ35_RS22200 ENOG41063M6 Cell Division Protein HHJ35_RS22215 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HHJ35_RS22230 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ35_RS22240 ENOG4105CBT Fructose-1,6-bisphosphatase HHJ35_RS22245 ENOG4105DP0 ferredoxin-NADP reductase HHJ35_RS22255 ENOG41065TG regulatoR HHJ35_RS22260 ENOG4108VTS Membrane HHJ35_RS22265 ENOG4105EBK exported protein HHJ35_RS22280 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HHJ35_RS22295 ENOG4105FMW periplasmic HHJ35_RS22300 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ35_RS22305 ENOG4105E0F Histidine kinase HHJ35_RS22310 ENOG4108RPX mosc domain containing protein HHJ35_RS22320 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ35_RS22380 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ35_RS22385 ENOG4108MG3 formate dehydrogenase HHJ35_RS22415 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system HHJ35_RS22425 ENOG4105SUU thioesterase domain HHJ35_RS22440 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HHJ35_RS22450 ENOG4105CSH Transporter HHJ35_RS22460 ENOG4105CPQ Dehydrogenase HHJ35_RS22465 ENOG4105D2M Aldolase HHJ35_RS22470 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ35_RS22475 ENOG4108MGF sugar kinase HHJ35_RS22480 ENOG4105E98 transcriptional regulator DeoR family HHJ35_RS22485 ENOG4105CI3 gtp-binding protein typa HHJ35_RS22490 ENOG4105C5F glutamine synthetase HHJ35_RS22495 ENOG4105CUX Signal transduction histidine kinase HHJ35_RS22500 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ35_RS22505 ENOG4106FIY HHJ35_RS22510 ENOG4105D4P Coproporphyrinogen iii oxidase HHJ35_RS22525 ENOG4105C2M dna polymerase I HHJ35_RS22530 ENOG4106HNH Acyl-transferase HHJ35_RS22540 ENOG4108Z33 Thiol disulfide Interchange Protein HHJ35_RS22545 ENOG4105E27 serine threonine protein kinase HHJ35_RS22550 ENOG4105PC1 Conserved Protein HHJ35_RS22555 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HHJ35_RS22560 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HHJ35_RS22590 ENOG4108RR8 protoporphyrinogen oxidase HHJ35_RS22595 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HHJ35_RS22600 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HHJ35_RS22620 ENOG4108EX3 reductase HHJ35_RS22625 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HHJ35_RS22630 ENOG4105MDZ Transcriptional activator rfaH HHJ35_RS22640 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HHJ35_RS22645 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HHJ35_RS22650 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HHJ35_RS22660 ENOG4105JC1 sterol-binding domain protein HHJ35_RS22670 ENOG4105CGY Dna recombination protein HHJ35_RS22675 ENOG4107HP6 Transcriptional regulator HHJ35_RS22680 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HHJ35_RS22685 ENOG4108RTU Aldolase HHJ35_RS22690 ENOG4105JN3 extra-cytoplasmic solute receptor family protein HHJ35_RS22705 ENOG4108I5U Uridine phosphorylase HHJ35_RS22710 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HHJ35_RS22715 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) HHJ35_RS22725 ENOG4107R1Q Membrane protein FdrA HHJ35_RS22730 ENOG4107REC cytoplasmic protein HHJ35_RS22735 ENOG4105C5B carbamate kinase HHJ35_RS22745 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HHJ35_RS22750 ENOG4105F52 Transcriptional regulator HHJ35_RS22755 ENOG4106KNT transcriptional regulator HHJ35_RS22760 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ35_RS22775 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ35_RS22795 ENOG4105DZ2 Transcriptional regulator HHJ35_RS22800 ENOG4105EMK carboxylate amino acid amine transporter HHJ35_RS22805 ENOG4105DQF Hydrolase HHJ35_RS22810 ENOG4108EUD Lysophospholipase HHJ35_RS22815 ENOG410829K Lysine exporter protein (Lyse ygga) HHJ35_RS22820 ENOG4105CCF Lysine exporter protein (Lyse ygga) HHJ35_RS22825 ENOG4105C9U ATP-dependent DNA helicase RecQ HHJ35_RS22830 ENOG4105HDD phospholipase HHJ35_RS22835 ENOG4108VUY thioesterase Superfamily protein HHJ35_RS22840 ENOG4105FR1 rard protein HHJ35_RS22855 ENOG4107QUT magnesium and cobalt transport protein CorA HHJ35_RS22860 ENOG4108T58 Mg2 transport protein CorA HHJ35_RS22865 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase HHJ35_RS22870 ENOG4105C4R Atp-dependent dna helicase HHJ35_RS22875 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HHJ35_RS22885 ENOG4105CT0 Protein of unknown function, DUF484 HHJ35_RS22895 ENOG4105S7Z (LipO)protein HHJ35_RS22915 ENOG4107T0K Adenylate cyclase HHJ35_RS22925 ENOG41076E6 Uroporphyrinogen-III Synthase HHJ35_RS22930 ENOG4105ECF c-methyltransferase HHJ35_RS22935 ENOG410601J HemY protein HHJ35_RS22940 ENOG4105ENH Sulfatase HHJ35_RS22945 ENOG4105C4X radical SAM domain protein HHJ35_RS22970 ENOG4105C85 amino acid HHJ35_RS22990 ENOG4105EGZ biosynthesis protein HHJ35_RS22995 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HHJ35_RS23000 ENOG4108WJ1 acetyltransferase HHJ35_RS23005 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HHJ35_RS23010 ENOG4105C1B dTDP-glucose 4-6-dehydratase HHJ35_RS23015 ENOG4107QQG Dehydrogenase HHJ35_RS23020 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HHJ35_RS23025 ENOG4105SFE lipopolysaccharide biosynthesis protein HHJ35_RS23030 ENOG4105ESV Glycosyl transferase, family 4 HHJ35_RS23035 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HHJ35_RS23060 ENOG4105C4R Atp-dependent dna helicase HHJ35_RS23065 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HHJ35_RS23075 ENOG4105EMY transcriptional regulator HHJ35_RS23080 ENOG4105C7B Threonine dehydratase HHJ35_RS23090 ENOG4105CM2 brancheD-chain amino acid aminotransferase HHJ35_RS23095 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HHJ35_RS23115 ENOG4105C0P Mg chelatase subunit ChlI HHJ35_RS23120 ENOG4108WFC UPF0438 protein yifE HHJ35_RS23160 ENOG4107EJG GntR family transcriptional regulator HHJ35_RS23165 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ35_RS23170 ENOG4105ETE Transcriptional regulator (LacI family HHJ35_RS23175 ENOG4108RVA ribokinase HHJ35_RS23180 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ35_RS23185 ENOG4105CNN ABC, transporter HHJ35_RS23220 ENOG4108VVK transcriptional Regulator, AsnC HHJ35_RS23225 ENOG4105QTB Flavodoxin HHJ35_RS23240 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HHJ35_RS23290 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HHJ35_RS23295 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HHJ35_RS23300 ENOG4105C8U phosphate abc transporter HHJ35_RS23305 ENOG4105E2Z phosphate ABC transporter (Permease HHJ35_RS23310 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HHJ35_RS23315 ENOG4108UTW Plays a role in the regulation of phosphate uptake HHJ35_RS23320 ENOG4105CID antiterminator HHJ35_RS23325 ENOG4105C5Y PTS System HHJ35_RS23330 ENOG4105CS2 ec 3.2.1.21 HHJ35_RS23340 ENOG4105DYC esterase HHJ35_RS23345 ENOG4107VKM 6-phosphogluconolactonase HHJ35_RS23360 ENOG4105C7N Xanthine uracil vitamin C permease HHJ35_RS23365 ENOG4108YYH Nadph-dependent fmn reductase HHJ35_RS23370 ENOG4105E8Q phosphopantetheinyl transferase HHJ35_RS23375 ENOG4105G2Y Transcriptional regulator HHJ35_RS23385 ENOG4108P6C Tryptophan transporter of low affinity HHJ35_RS23420 ENOG4105VG0 50S ribosomal protein l34 HHJ35_RS23465 ENOG4107ENK receptor HHJ35_RS23495 ENOG4108YXQ IS66 Orf2 family protein HHJ35_RS23510 ENOG4105EKQ RNA-directed DNA polymerase HHJ35_RS23555 ENOG41063SR receptor HHJ35_RS23590 ENOG4105EKQ RNA-directed DNA polymerase HHJ35_RS23610 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HHJ35_RS23615 ENOG4107R39 (ABC) transporter HHJ35_RS23620 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HHJ35_RS23635 ENOG4107SJW iron permease, FTR1 HHJ35_RS23640 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) HHJ35_RS23645 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HHJ35_RS23655 ENOG4108BUD transposase HHJ35_RS23660 ENOG4106CQM replication HHJ35_RS23670 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) HHJ35_RS23685 ENOG4105KK6 nuclease HHJ35_RS23695 ENOG4107CBI conjugal transfer fertility inhibition protein HHJ35_RS23700 ENOG4107U2T alpha beta HHJ35_RS23930 ENOG4105FEQ ParB domain protein nuclease HHJ35_RS23995 ENOG41073YN Protein of unknown function (DUF1380)