locus-tag class description HHJ40_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HHJ40_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ40_RS00025 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HHJ40_RS00030 ENOG410667J hydrolase HHJ40_RS00035 ENOG410657R replicase EC 2.7 HHJ40_RS00040 ENOG4105EMF GntR family transcriptional regulator HHJ40_RS00045 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HHJ40_RS00050 ENOG4108RTU Aldolase HHJ40_RS00060 ENOG4105DJB Major Facilitator Superfamily HHJ40_RS00070 ENOG4105D99 atp gtp-binding protein HHJ40_RS00075 ENOG4105R2A (LipO)protein HHJ40_RS00095 ENOG4105FDP GntR family transcriptional regulator HHJ40_RS00100 ENOG4105CI1 PTS System HHJ40_RS00110 ENOG4108AHD Transcriptional regulator HHJ40_RS00115 ENOG4107RUZ Sss sodium solute transporter superfamily HHJ40_RS00120 ENOG4105CBG Sulfatase HHJ40_RS00125 ENOG4106DRA Inner membrane protein YidI HHJ40_RS00130 ENOG4105VG5 Membrane HHJ40_RS00135 ENOG4105JP4 Inner membrane protein yidG HHJ40_RS00140 ENOG4105J13 transcriptional regulator HHJ40_RS00145 ENOG4105E5M Multidrug resistance protein D HHJ40_RS00160 ENOG4105C7K acetolactate synthase HHJ40_RS00165 ENOG4105M71 acetolactate synthase 1 regulatory subunit HHJ40_RS00170 ENOG4108KX4 response regulator HHJ40_RS00175 ENOG4105BZU Histidine kinase HHJ40_RS00180 ENOG4105CXY transporter HHJ40_RS00185 ENOG4105CXY transporter HHJ40_RS00195 ENOG4105C7N Xanthine uracil vitamin C permease HHJ40_RS00200 ENOG4108SAJ Protein of unknown function (DUF1198) HHJ40_RS00210 ENOG4105T8A Uncharacterized protein YicS HHJ40_RS00215 ENOG4105D01 (LipO)protein HHJ40_RS00220 ENOG4108UZ3 Transporter HHJ40_RS00225 ENOG4105S8Q sugar efflux transporter HHJ40_RS00255 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ40_RS00265 ENOG4108YGG dna repair protein HHJ40_RS00270 ENOG4105MFG Antirestriction protein HHJ40_RS00275 ENOG4106H6R UPF0380 protein HHJ40_RS00285 ENOG4105F4K antigen 43 HHJ40_RS00360 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ40_RS00365 ENOG4105C2D reductase HHJ40_RS00375 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ40_RS00400 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) HHJ40_RS00405 ENOG4108RKI Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity) HHJ40_RS00430 ENOG4105E9Q Acyl-transferase HHJ40_RS00450 ENOG4105D5K Hemolysin activator protein HHJ40_RS00475 ENOG4107SCJ type I restriction enzyme EcoKI subunit R HHJ40_RS00515 ENOG4105DFP Integrase HHJ40_RS00525 ENOG4105CT4 transporter HHJ40_RS00530 ENOG4105CJQ hydrolase, family 31 HHJ40_RS00535 ENOG4105JV1 AsmA family HHJ40_RS00540 ENOG4105C2W permease HHJ40_RS00545 ENOG4105D6U Sodium Glutamate Symporter HHJ40_RS00555 ENOG4105CB5 ATP-dependent DNA helicase recG HHJ40_RS00560 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HHJ40_RS00565 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ40_RS00575 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HHJ40_RS00585 ENOG4105EN6 Membrane HHJ40_RS00590 ENOG4105F5P DNA-damage-inducible protein d HHJ40_RS00595 ENOG4105DSJ YicC domain protein HHJ40_RS00615 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) HHJ40_RS00620 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HHJ40_RS00630 ENOG4105KDC 50s ribosomal protein l28 HHJ40_RS00650 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HHJ40_RS00655 ENOG4105DKP glycosyl transferase, family 9 HHJ40_RS00660 ENOG4107RJ7 Glycosyl transferase (Group 1 HHJ40_RS00665 ENOG4107543 (lipo)polysaccharide HHJ40_RS00680 ENOG4105X1N Glycosyl transferase family 8 HHJ40_RS00685 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase HHJ40_RS00690 ENOG4108FRV O-antigen ligase HHJ40_RS00695 ENOG4105D16 lipopolysaccharide heptosyltransferase i HHJ40_RS00700 ENOG4105XA0 heptosyltransferase ii HHJ40_RS00710 ENOG4108SEH involved in lipopolysaccharide biosynthesis HHJ40_RS00715 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ40_RS00725 ENOG4105K64 Glycosyl transferase, family 2 HHJ40_RS00730 ENOG4105PXI polysaccharide deacetylase HHJ40_RS00735 ENOG41063SB peptidase HHJ40_RS00745 ENOG4107YZP Rhodanese domain protein HHJ40_RS00750 ENOG4105VW4 glutaredoxin 3 HHJ40_RS00765 ENOG4105D7W serine acetyltransferase HHJ40_RS00770 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HHJ40_RS00780 ENOG41073TP transcriptional regulator HHJ40_RS00785 ENOG4105DAA L-lactate HHJ40_RS00790 ENOG4105EUR Domain-Containing protein HHJ40_RS00795 ENOG4108WY4 inner membrane lipoprotein HHJ40_RS00800 ENOG4108YYI Protein of unknown function (DUF2810) HHJ40_RS00810 ENOG4105E61 Mannitol repressor protein HHJ40_RS00820 ENOG4105CTS PTS system mannitol-specific HHJ40_RS00825 ENOG4105FP6 Protein of unknown function (DUF3302) HHJ40_RS00830 ENOG4105EFX secretion protein, HlyD family HHJ40_RS00865 ENOG4105CNA YD repeat protein HHJ40_RS00870 ENOG4105CNA YD repeat protein HHJ40_RS00885 ENOG4108U78 Glutathione S-transferase HHJ40_RS00895 ENOG4105EM7 Selenocysteine-specific translation elongation factor HHJ40_RS00900 ENOG4105C0A alcohol dehydrogenase HHJ40_RS00905 ENOG4105C26 Dehydrogenase HHJ40_RS00915 ENOG4105KK7 inner membrane protein YiaW HHJ40_RS00920 ENOG4105EFX secretion protein, HlyD family HHJ40_RS00925 ENOG4108Q2M Transcriptional regulator HHJ40_RS00930 ENOG4105GNX MltA-interacting MipA family protein HHJ40_RS00940 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ40_RS00945 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HHJ40_RS00950 ENOG4105H6Q decarboxylase HHJ40_RS00955 ENOG4105CMG Carbohydrate kinase HHJ40_RS00960 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ40_RS00965 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ40_RS00970 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HHJ40_RS00975 ENOG4108R66 Conserved Protein HHJ40_RS00985 ENOG4105J4Q Transcriptional regulator HHJ40_RS00990 ENOG4108XIB electron transport protein ysaA HHJ40_RS00995 ENOG4105JKW Valine--pyruvate aminotransferase HHJ40_RS01000 ENOG4107T9C Alpha amylase catalytic region HHJ40_RS01005 ENOG4108UR8 BAX protein HHJ40_RS01010 ENOG4105T16 Transcriptional regulator (AraC family) HHJ40_RS01015 ENOG4108HWW ABC transporter HHJ40_RS01020 ENOG4105C2J ABC transporter HHJ40_RS01025 ENOG4105DFW ABC transporter HHJ40_RS01035 ENOG4105CMG Carbohydrate kinase HHJ40_RS01040 ENOG410688U Inner membrane protein yiaB HHJ40_RS01045 ENOG4108Z12 YiaAB two helix domain-containing protein HHJ40_RS01050 ENOG4105MEV Acyl-transferase HHJ40_RS01070 ENOG41060TC Hok gef cell toxic protein HHJ40_RS01080 ENOG4105MVF Transcriptional regulator HHJ40_RS01085 ENOG4106JH6 (LipO)protein HHJ40_RS01095 ENOG4108ZG0 Ompa motb domain protein HHJ40_RS01100 ENOG4107QY8 reductase HHJ40_RS01105 ENOG4105HNP -acetyltransferase HHJ40_RS01110 ENOG4108R3E Dna-3-methyladenine glycosylase i HHJ40_RS01115 ENOG4105EAX Putative lipase HHJ40_RS01120 ENOG4105FCD Major Facilitator HHJ40_RS01125 ENOG4106EAR Fimbrial protein HHJ40_RS01130 ENOG4108VCD Chaperone HHJ40_RS01135 ENOG4105CW0 outer membrane usher protein HHJ40_RS01140 ENOG4105MHR Fimbrial protein HHJ40_RS01145 ENOG4106UCC Fimbrial protein HHJ40_RS01150 ENOG4105DIJ Phosphoethanolamine transferase HHJ40_RS01165 ENOG4105DEF Extracellular solute-binding protein, family 5 HHJ40_RS01170 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ40_RS01175 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ40_RS01180 ENOG4105C3U ABC transporter HHJ40_RS01185 ENOG4108JQ7 (ABC) transporter HHJ40_RS01190 ENOG4105C44 Serine transporter HHJ40_RS01210 ENOG4105D1V cellulose synthase operon protein YhjU HHJ40_RS01215 ENOG4105WQA Cellulose biosynthesis protein BcsF HHJ40_RS01220 ENOG4105U74 cellulose biosynthesis protein BcsE HHJ40_RS01225 ENOG410661M cytoplasmic protein HHJ40_RS01235 ENOG4107QZ7 Cellulose synthase catalytic subunit HHJ40_RS01240 ENOG4107EEX Cellulose synthase regulator protein HHJ40_RS01245 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HHJ40_RS01250 ENOG4105EJG cellulose synthase HHJ40_RS01255 ENOG4105BZU Histidine kinase HHJ40_RS01265 ENOG4105CS0 peptidase HHJ40_RS01275 ENOG4105CMB EAL domain-containing protein HHJ40_RS01280 ENOG41066T0 asmA family HHJ40_RS01285 ENOG4105CSH Transporter HHJ40_RS01290 ENOG4107H3J ribonuclease HHJ40_RS01295 ENOG4105CBN LysR family transcriptional regulator HHJ40_RS01300 ENOG4106S2D Transcriptional regulator HHJ40_RS01310 ENOG4105CA0 peroxidase HHJ40_RS01315 ENOG4105CVK Glutamate decarboxylase HHJ40_RS01320 ENOG4108NKV transcriptional regulator HHJ40_RS01330 ENOG4105BZS acriflavin resistance protein HHJ40_RS01335 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ40_RS01345 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HHJ40_RS01350 ENOG4108YK4 Acid-resistance membrane protein HHJ40_RS01355 ENOG41060V2 Acid-resistance protein HHJ40_RS01360 ENOG4105XXV Acid-resistance protein HHJ40_RS01365 ENOG4105KT7 mgtC SapB transporter HHJ40_RS01375 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ40_RS01395 ENOG4105K89 arsenate reductase HHJ40_RS01400 ENOG4107R5R arsenical pump membrane protein HHJ40_RS01405 ENOG4105KBH arsR family transcriptional regulator HHJ40_RS01415 ENOG4105DC8 reductase HHJ40_RS01420 ENOG4105D6S protein involved in catabolism of external DNA HHJ40_RS01425 ENOG4105DGW oligopeptidase A HHJ40_RS01435 ENOG4105DUX Transporter HHJ40_RS01450 ENOG4105CJ3 phosphate transporter HHJ40_RS01455 ENOG4105CBX hi0933 family HHJ40_RS01460 ENOG4107UNS conserved inner membrane protein HHJ40_RS01475 ENOG4105D0S secretion protein (HlyD HHJ40_RS01480 ENOG4105CJ1 ABC, transporter HHJ40_RS01485 ENOG4105CMI transporter HHJ40_RS01510 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HHJ40_RS01515 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ40_RS01520 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ40_RS01525 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HHJ40_RS01530 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HHJ40_RS01535 ENOG4105DSF transport protein HHJ40_RS01540 ENOG4105F9N Major Facilitator Superfamily HHJ40_RS01545 ENOG4108W1V Lipoprotein HHJ40_RS01550 ENOG4105EX9 Membrane HHJ40_RS01565 ENOG4107FS9 Membrane HHJ40_RS01575 ENOG4105MG3 Membrane HHJ40_RS01580 ENOG4106H78 methyltransferase HHJ40_RS01585 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HHJ40_RS01590 ENOG4105CAK Cell division ATP-binding protein ftsE HHJ40_RS01595 ENOG4105CRP Part of the ABC transporter FtsEX involved in HHJ40_RS01600 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ40_RS01605 ENOG4105CP9 extracellular ligand-binding receptor HHJ40_RS01610 ENOG4105U59 -acetyltransferase HHJ40_RS01615 ENOG4105CP9 extracellular ligand-binding receptor HHJ40_RS01620 ENOG4105C32 Amino acid ABC transporter (Permease) HHJ40_RS01625 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HHJ40_RS01630 ENOG4105C0Z ABC transporter HHJ40_RS01635 ENOG4108IV0 ABC, transporter HHJ40_RS01645 ENOG4105BZ7 extracellular solute-binding protein family 1 HHJ40_RS01650 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component HHJ40_RS01655 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component HHJ40_RS01660 ENOG4108IJ9 (ABC) transporter HHJ40_RS01665 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HHJ40_RS01670 ENOG4105WC8 Conserved Protein HHJ40_RS01675 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HHJ40_RS01680 ENOG4106FA4 HHJ40_RS01695 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ40_RS01700 ENOG4105WCN acetyltransferase HHJ40_RS01705 ENOG4105D9R oxidoreductase HHJ40_RS01710 ENOG4105C2I pirin domain protein HHJ40_RS01715 ENOG4105DIQ Transcriptional regulator HHJ40_RS01720 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HHJ40_RS01725 ENOG4105C6Z Gluconate HHJ40_RS01730 ENOG4105C9U ATP-dependent DNA helicase RecQ HHJ40_RS01740 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HHJ40_RS01745 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ40_RS01755 ENOG4108IUM Glycogen debranching enzyme HHJ40_RS01770 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ40_RS01795 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HHJ40_RS01810 ENOG4105E98 transcriptional regulator DeoR family HHJ40_RS01815 ENOG4105CYB regulatoR HHJ40_RS01820 ENOG4105E0Y RtcB Protein HHJ40_RS01835 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ40_RS01840 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HHJ40_RS01845 ENOG4105C6Z Gluconate HHJ40_RS01855 ENOG4105MJ2 Competence protein HHJ40_RS01865 ENOG4105DNE Transposase HHJ40_RS01875 ENOG4105CE1 Ferrous iron transport protein b HHJ40_RS01880 ENOG4105XFK Ferrous iron transport protein A HHJ40_RS01885 ENOG4105BZM domain protein HHJ40_RS01890 ENOG4108RRZ Transcription elongation factor GreB HHJ40_RS01900 ENOG4105E0F Histidine kinase HHJ40_RS01910 ENOG4108MAJ Membrane HHJ40_RS01920 ENOG4105VEJ Heat shock protein HHJ40_RS01925 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HHJ40_RS01930 ENOG4105DQY intracellular growth attenuator HHJ40_RS01935 ENOG4107RK2 ADP-ribose diphosphatase NudE HHJ40_RS01940 ENOG4108JQC penicillin-binding protein 1A HHJ40_RS01945 ENOG4108U1Q Pilus assembly protein HHJ40_RS01950 ENOG41065NF Fimbrial assembly family protein HHJ40_RS01955 ENOG4105XPX DNA utilization protein HofO HHJ40_RS01960 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HHJ40_RS01965 ENOG4105E4G Type IV pilus HHJ40_RS01980 ENOG4105EGB membrane protein DamX HHJ40_RS01985 ENOG4105DFE Dna adenine methylase HHJ40_RS01990 ENOG4105DJV ribulose-phosphate 3-epimerase HHJ40_RS02000 ENOG4105C31 Tryptophanyl-tRNA synthetase HHJ40_RS02005 ENOG4108M21 HHJ40_RS02010 ENOG4105RMW regulation of transcription, DNA-dependent HHJ40_RS02015 ENOG4108626 Racemase HHJ40_RS02020 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HHJ40_RS02025 ENOG41080QX K07048 phosphotriesterase-related protein HHJ40_RS02030 ENOG4105MUZ Protein of unknown function DUF2620 HHJ40_RS02035 ENOG4106M0N transport system permease protein HHJ40_RS02040 ENOG4106PKC pyridoxal phosphate binding HHJ40_RS02045 ENOG4105FDP GntR family transcriptional regulator HHJ40_RS02050 ENOG4108KPW sugar kinase HHJ40_RS02055 ENOG4107Y0V Not clear, may be involved in an isomerization step HHJ40_RS02060 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine HHJ40_RS02065 ENOG4107QHQ amino acid HHJ40_RS02070 ENOG4105VYH HHJ40_RS02080 ENOG4107V9H nitrite transporter HHJ40_RS02085 ENOG4105WZK nitrite reductase NADPH small subunit HHJ40_RS02090 ENOG4107QZF nitrite reductase NADPH large subunit HHJ40_RS02100 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ40_RS02110 ENOG4105MZU cell filamentation protein HHJ40_RS02115 ENOG4105DDQ anthranilate synthase HHJ40_RS02120 ENOG4105C8Y Acetylornithine aminotransferase HHJ40_RS02125 ENOG410613R integral membrane protein, YccS YhfK family HHJ40_RS02135 ENOG4108UKZ OsmC family HHJ40_RS02140 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HHJ40_RS02150 ENOG4105DNZ Alpha Beta Hydrolase HHJ40_RS02155 ENOG4105C5H ABC transporter HHJ40_RS02170 ENOG4105VKU nucleicacid-binding protein HHJ40_RS02175 ENOG4108YZY peptidylprolyl cis-trans isomerase HHJ40_RS02185 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ40_RS02190 ENOG4105WWK YheO domain protein HHJ40_RS02230 ENOG4105W53 bacterioferritin-associated ferredoxin HHJ40_RS02235 ENOG4108UQY Iron-storage protein HHJ40_RS02260 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HHJ40_RS02305 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) HHJ40_RS02350 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HHJ40_RS02355 ENOG41067V7 50S ribosomal protein L36 HHJ40_RS02385 ENOG4105VTS DnaJ-like, subfamily C HHJ40_RS02390 ENOG4105W1Y Transcriptional regulator HHJ40_RS02395 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HHJ40_RS02405 ENOG4105C1A potassium transporter peripheral membrane HHJ40_RS02425 ENOG4105C79 DNA protecting protein DprA HHJ40_RS02435 ENOG4108WI1 Dna topoisomerase HHJ40_RS02450 ENOG4105SG3 Protein of unknown function (DUF1488) HHJ40_RS02455 ENOG4108Z0R Transferase HHJ40_RS02490 ENOG4105CDA abc transporter atp-binding protein HHJ40_RS02495 ENOG4105DRP amino acid AbC transporter HHJ40_RS02500 ENOG4105EZ7 amino acid ABC transporter HHJ40_RS02510 ENOG4105XCM membrane LIPOPROTEIN HHJ40_RS02515 ENOG4105BZS acriflavin resistance protein HHJ40_RS02520 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ40_RS02525 ENOG4108XG4 DNA-binding transcriptional regulator HHJ40_RS02530 ENOG41061ME transport protein HHJ40_RS02535 ENOG4105CEC DNA methylase N-4 N-6 HHJ40_RS02545 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ40_RS02555 ENOG4108IA2 Sodium pantothenate symporter HHJ40_RS02560 ENOG4105RG0 Membrane HHJ40_RS02565 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HHJ40_RS02570 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HHJ40_RS02575 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HHJ40_RS02580 ENOG41062P1 Diguanylate cyclase phosphodiesterase HHJ40_RS02590 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HHJ40_RS02595 ENOG4105VQ7 Rod shape-determining protein MreD HHJ40_RS02605 ENOG4105C03 ribonuclease HHJ40_RS02610 ENOG4105QD6 exported protein HHJ40_RS02615 ENOG4105D1U peptidase U62 modulator of DNA gyrase HHJ40_RS02620 ENOG4105CR8 Transcriptional regulator HHJ40_RS02625 ENOG4105ZQC membrane protein AaeX HHJ40_RS02640 ENOG4105UNR (Barnase) inhibitor HHJ40_RS02645 ENOG4105RID UPF0379 protein yhcN HHJ40_RS02660 ENOG4105C0H protease HHJ40_RS02665 ENOG4105C0H protease HHJ40_RS02670 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HHJ40_RS02675 ENOG4105D6Z AFG1 family ATPase HHJ40_RS02690 ENOG4107MKT Stringent starvation protein a HHJ40_RS02695 ENOG4105KB2 stringent starvation protein b HHJ40_RS02700 ENOG4105CEE C4-dicarboxylate transporter HHJ40_RS02705 ENOG4108QBF Transcriptional regulator HHJ40_RS02730 ENOG4108R66 Conserved Protein HHJ40_RS02735 ENOG4105DFS Conserved Protein HHJ40_RS02740 ENOG4105BZ8 glutamate synthase HHJ40_RS02745 ENOG4105CBC glutamate synthase HHJ40_RS02750 ENOG4105N5T Radical SAM Protein HHJ40_RS02755 ENOG4105BZU Histidine kinase HHJ40_RS02760 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HHJ40_RS02770 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HHJ40_RS02775 ENOG41080Z8 PHOSPHOCARRIER protein HHJ40_RS02785 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HHJ40_RS02790 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HHJ40_RS02795 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ40_RS02800 ENOG4108IUZ ABC transporter HHJ40_RS02805 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HHJ40_RS02810 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HHJ40_RS02820 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ40_RS02825 ENOG4105FEU K -dependent Na -Ca exchanger HHJ40_RS02830 ENOG4105DHJ ABC, transporter HHJ40_RS02835 ENOG4105CY3 ABC transporter, permease HHJ40_RS02840 ENOG4107PE3 Mammalian cell entry related domain protein HHJ40_RS02845 ENOG4105E3I toluene tolerance HHJ40_RS02850 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HHJ40_RS02855 ENOG4105VFK BolA family HHJ40_RS02865 ENOG4105HVQ Regulatory factor of maltose metabolism HHJ40_RS02870 ENOG4105EAH synthase HHJ40_RS02885 ENOG4105QYV Membrane HHJ40_RS02895 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HHJ40_RS02900 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HHJ40_RS02905 ENOG4105HBR Rna-binding protein HHJ40_RS02915 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HHJ40_RS02920 ENOG4105EEI dihydropteroate synthase HHJ40_RS02930 ENOG4105NTZ Preprotein translocase subunit SecG HHJ40_RS02940 ENOG4105DIJ Phosphoethanolamine transferase HHJ40_RS02960 ENOG4105CHV Transcription elongation factor NusA HHJ40_RS03000 ENOG4105C1J atp-dependent rna helicase HHJ40_RS03005 ENOG4105CIC tryptophan-specific transport protein HHJ40_RS03010 ENOG4105DEN Luciferase family HHJ40_RS03030 ENOG4108YYD acetyltransferase HHJ40_RS03045 ENOG4107R7Y intracellular protease Pfpi family HHJ40_RS03050 ENOG4105K4T epimerase HHJ40_RS03055 ENOG4107S21 permease HHJ40_RS03060 ENOG4105W4M Transport-associated protein HHJ40_RS03080 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HHJ40_RS03085 ENOG4105I74 Fimbrial protein HHJ40_RS03090 ENOG4105CW0 outer membrane usher protein HHJ40_RS03095 ENOG4108VCD Chaperone HHJ40_RS03100 ENOG4105Q10 Fimbrial-like protein HHJ40_RS03105 ENOG4106HBN Galactosamine-6-phosphate isomerase HHJ40_RS03110 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ40_RS03115 ENOG4105ETZ PTS System HHJ40_RS03120 ENOG4108UZY PTS System HHJ40_RS03130 ENOG4105E70 isomerase HHJ40_RS03135 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ40_RS03140 ENOG4108YTN IIa component HHJ40_RS03145 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ40_RS03155 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HHJ40_RS03165 ENOG4105E98 transcriptional regulator DeoR family HHJ40_RS03170 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression HHJ40_RS03175 ENOG4105ZEG Suppressor protein HHJ40_RS03180 ENOG4105CTX dehydratase HHJ40_RS03185 ENOG4105DJB Major Facilitator Superfamily HHJ40_RS03195 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ40_RS03200 ENOG4105BZW Glycerate kinase HHJ40_RS03230 ENOG410811B TRANSCRIPTIONal HHJ40_RS03235 ENOG4105C7B Threonine dehydratase HHJ40_RS03245 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HHJ40_RS03250 ENOG4105C6N Formate acetyltransferase HHJ40_RS03255 ENOG4105KME endoribonuclease L-psp HHJ40_RS03260 ENOG4105EJQ L-serine dehydratase HHJ40_RS03265 ENOG4105C44 Serine transporter HHJ40_RS03275 ENOG4106D80 Uncharacterized protein YhaL HHJ40_RS03280 ENOG4108CNN domain protein HHJ40_RS03285 ENOG4105CWB LysR family transcriptional Regulator HHJ40_RS03290 ENOG4105KAF membrAne HHJ40_RS03295 ENOG4105KAF membrAne HHJ40_RS03300 ENOG4105CHF Glutathione S-transferase HHJ40_RS03305 ENOG4108VBZ doxx family HHJ40_RS03310 ENOG4105YJD HHJ40_RS03315 ENOG41090KG Inner membrane protein YqjE HHJ40_RS03320 ENOG4105NE1 Conserved Protein HHJ40_RS03325 ENOG4105WAY exported protein HHJ40_RS03330 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HHJ40_RS03335 ENOG4106W5V Membrane HHJ40_RS03340 ENOG4107YCY Transcriptional regulator HHJ40_RS03365 ENOG4105DPW Major facilitator superfamily MFS_1 HHJ40_RS03375 ENOG4105CTX dehydratase HHJ40_RS03380 ENOG4105P66 Membrane HHJ40_RS03385 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) HHJ40_RS03390 ENOG4105DU1 integral membrane protein, terc HHJ40_RS03395 ENOG4105EE0 oxidoreductase HHJ40_RS03400 ENOG4108UB4 uncharacterized protein ygjQ HHJ40_RS03405 ENOG4108VKG metal-dependent hydrolase HHJ40_RS03415 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ40_RS03420 ENOG4107WCA isomerase HHJ40_RS03425 ENOG4107W6W Conserved Protein HHJ40_RS03430 ENOG4105E5D amino acid HHJ40_RS03435 ENOG4105FK9 beta-D-galactosidase beta subunit HHJ40_RS03440 ENOG4105CNT hydrolase family 2 HHJ40_RS03445 ENOG4105CQ4 Transcriptional regulator HHJ40_RS03450 ENOG4108Y51 tRNA-binding protein HHJ40_RS03460 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HHJ40_RS03465 ENOG4105NTW Transcriptional regulator HHJ40_RS03470 ENOG4105Q26 Siderophore-interacting protein HHJ40_RS03485 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ40_RS03490 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HHJ40_RS03505 ENOG4107QPK )-transporter HHJ40_RS03510 ENOG4107GFK fumarate HHJ40_RS03515 ENOG4106DSS Tartrate dehydratase subunit alpha HHJ40_RS03520 ENOG4105EJC lysr family transcriptional regulator HHJ40_RS03530 ENOG4107ZVW dihydroneopterin aldolase HHJ40_RS03545 ENOG4106MWK domain protein HHJ40_RS03550 ENOG4105I7R Adenylate cyclase HHJ40_RS03575 ENOG4107S78 Band 7 protein HHJ40_RS03580 ENOG4105PV3 Inner membrane protein yqiJ HHJ40_RS03590 ENOG4108MY7 Fimbrial HHJ40_RS03595 ENOG4108TTM chaperone HHJ40_RS03605 ENOG4105H8W Fimbrial protein HHJ40_RS03610 ENOG4105W0Z cytoplasmic protein HHJ40_RS03630 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HHJ40_RS03635 ENOG4106032 Glutathionylspermidine synthase HHJ40_RS03645 ENOG4105DFG type I secretion outer membrane protein HHJ40_RS03650 ENOG41087AY ADP-Ribose pyrophosphatase HHJ40_RS03655 ENOG4108SX3 cytoplasmic protein HHJ40_RS03660 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HHJ40_RS03665 ENOG4105IPS esterase HHJ40_RS03670 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ40_RS03675 ENOG4105VRH Antibiotic biosynthesis monooxygenase HHJ40_RS03680 ENOG4105NF4 modulator of drug activity HHJ40_RS03685 ENOG4107DEU Inner membrane protein YgiZ HHJ40_RS03690 ENOG4105DHQ Histidine kinase HHJ40_RS03695 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ40_RS03700 ENOG4105H4F exported protein HHJ40_RS03705 ENOG4105F4I Transcriptional regulator HHJ40_RS03710 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ40_RS03715 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HHJ40_RS03720 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HHJ40_RS03725 ENOG4105CCT upf0313 protein HHJ40_RS03735 ENOG4105ZKC Conserved Protein HHJ40_RS03740 ENOG4105CV8 reductase HHJ40_RS03745 ENOG4108I6A alcohol dehydrogenase HHJ40_RS03750 ENOG4105CF7 AraC family transcriptional regulator HHJ40_RS03755 ENOG4108K81 inner membrane protein YghB HHJ40_RS03760 ENOG4105C28 cystathionine HHJ40_RS03765 ENOG4105CWK Biopolymer transport protein, ExbB HHJ40_RS03770 ENOG4108ZZF transport protein (ExbD) HHJ40_RS03775 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HHJ40_RS03785 ENOG4105CPC Aldo Keto reductase HHJ40_RS03795 ENOG410900S Protein of unknown function (DUF2623) HHJ40_RS03800 ENOG4105E3S small subunit HHJ40_RS03805 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ40_RS03810 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HHJ40_RS03815 ENOG4105DPX Hydrogenase, large subunit HHJ40_RS03820 ENOG4108USZ hydrogenase HHJ40_RS03825 ENOG4108WGS hydrogenase 2-specific chaperone HHJ40_RS03835 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HHJ40_RS03845 ENOG4105CYM Glutathione S-transferase HHJ40_RS03850 ENOG4106032 Glutathionylspermidine synthase HHJ40_RS03855 ENOG4105CJ3 phosphate transporter HHJ40_RS03860 ENOG4108GH0 ATP-binding protein yghT HHJ40_RS03865 ENOG4108NDC ATP-binding protein yghS HHJ40_RS03870 ENOG4106FPV ATP-binding protein YghR HHJ40_RS03875 ENOG4108S55 polysaccharide biosynthesis protein HHJ40_RS03885 ENOG4108UUE Transcriptional regulator HHJ40_RS03890 ENOG4108M8S permease YjgP YjgQ family protein HHJ40_RS03900 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ40_RS03905 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ40_RS03915 ENOG4107RCI amp-dependent synthetase and ligase HHJ40_RS03925 ENOG4108KWP DNA-binding transcriptional regulator GlcC HHJ40_RS03930 ENOG4105CQB FAD linked oxidase domain protein HHJ40_RS03935 ENOG4105EU8 FAD linked oxidase domain protein HHJ40_RS03940 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ40_RS03945 ENOG4108ZJF Glcg protein HHJ40_RS03950 ENOG4107QP3 malate synthase g HHJ40_RS03955 ENOG4105DAA L-lactate HHJ40_RS03985 ENOG4107QHF type ii secretion system protein e HHJ40_RS03990 ENOG4105D7Q type ii secretion system HHJ40_RS03995 ENOG4108VAU general secretion pathway protein G HHJ40_RS04005 ENOG4105X5Z General secretion pathway protein I HHJ40_RS04025 ENOG4105U1E general secretion pathway protein M HHJ40_RS04035 ENOG4108UQV Membrane HHJ40_RS04040 ENOG4105CXN decarboxylase HHJ40_RS04045 ENOG4105EAA nucleoside HHJ40_RS04060 ENOG4105CEN a g-specific adenine glycosylase HHJ40_RS04070 ENOG41090ED Protein with unknown function (DUF469) HHJ40_RS04075 ENOG4105K33 Periplasmic Protein HHJ40_RS04080 ENOG4105HDK L-asparaginase HHJ40_RS04085 ENOG4106MH3 alpha helix chain HHJ40_RS04090 ENOG4105CSA Coproporphyrinogen iii oxidase HHJ40_RS04095 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ40_RS04105 ENOG4108VIA integral membrane protein HHJ40_RS04110 ENOG4105DFA alanine racemase domain protein HHJ40_RS04115 ENOG4105CZX twitching motility protein HHJ40_RS04130 ENOG4105D7Z glutathione synthase HHJ40_RS04135 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HHJ40_RS04140 ENOG4105RWS endonuclease I HHJ40_RS04150 ENOG4107QNK )-transporter HHJ40_RS04170 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HHJ40_RS04195 ENOG4105DAS pts system HHJ40_RS04200 ENOG4105ETZ PTS System HHJ40_RS04205 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ40_RS04220 ENOG4108K0D peptidase, M48 HHJ40_RS04225 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ40_RS04230 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HHJ40_RS04235 ENOG4105CTS PTS system mannitol-specific HHJ40_RS04240 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HHJ40_RS04245 ENOG4108Q8A Fructose-1,6-bisphosphatase HHJ40_RS04250 ENOG4108R4K DNA-binding, transcriptional regulator HHJ40_RS04255 ENOG4107Z1W Fructose transport system kinase HHJ40_RS04260 ENOG4108JJB ABC transporter HHJ40_RS04265 ENOG4108JJB ABC transporter HHJ40_RS04295 ENOG4105D2N Aldolase HHJ40_RS04300 ENOG4105D64 Mechanosensitive ion channel HHJ40_RS04305 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HHJ40_RS04310 ENOG4105MPN Membrane HHJ40_RS04315 ENOG4105DEQ transcriptional regulator HHJ40_RS04320 ENOG4105CYC Transferase HHJ40_RS04325 ENOG4108M7F enoyl-CoA hydratase isomerase HHJ40_RS04330 ENOG4105DJT lAO AO transport system ATPase HHJ40_RS04335 ENOG4105D5P Methylmalonyl-coA mutase HHJ40_RS04355 ENOG4108JQ1 Dehydrogenase HHJ40_RS04370 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HHJ40_RS04390 ENOG4107RAQ aminopeptidase HHJ40_RS04395 ENOG4105D0A hydroxylase HHJ40_RS04400 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ40_RS04425 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HHJ40_RS04430 ENOG4105CS2 ec 3.2.1.21 HHJ40_RS04440 ENOG4108UT2 hemolysin iii HHJ40_RS04450 ENOG4105Y75 tpr repeat protein HHJ40_RS04455 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HHJ40_RS04460 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HHJ40_RS04465 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HHJ40_RS04470 ENOG4105T95 Thiol disulfide interChange protein HHJ40_RS04475 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HHJ40_RS04505 ENOG4105C2W permease HHJ40_RS04510 ENOG4105BZ8 glutamate synthase HHJ40_RS04515 ENOG4108R8B oxidoreductase Fe-S subunit HHJ40_RS04520 ENOG4105C7N Xanthine uracil vitamin C permease HHJ40_RS04525 ENOG4107QUY Guanine deaminase HHJ40_RS04530 ENOG4105C2W permease HHJ40_RS04535 ENOG4105C7W Xanthine dehydrogenase HHJ40_RS04540 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HHJ40_RS04545 ENOG4107UUR Chlorohydrolase aminohydrolase HHJ40_RS04550 ENOG4105BZ8 glutamate synthase HHJ40_RS04555 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HHJ40_RS04560 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HHJ40_RS04565 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HHJ40_RS04570 ENOG4105C5B carbamate kinase HHJ40_RS04580 ENOG4107S4Y M20 DapE family protein YgeY HHJ40_RS04585 ENOG4107RCH Diaminopropionate ammonia-lyase HHJ40_RS04590 ENOG4105IW6 Carbamoyltransferase HHJ40_RS04595 ENOG4108JUB Transcriptional regulator HHJ40_RS04600 ENOG4108UTP (2Fe-2S)-binding domain protein HHJ40_RS04605 ENOG4108HR6 Dehydrogenase HHJ40_RS04610 ENOG4105C7W Xanthine dehydrogenase HHJ40_RS04615 ENOG4108K5P (LipO)protein HHJ40_RS04625 ENOG4108T88 HHJ40_RS04645 ENOG4108TN6 type iii secretion HHJ40_RS04680 ENOG4105Y7Q type iii secretion HHJ40_RS04715 ENOG4108YAB Invasion protein HHJ40_RS04740 ENOG4105FV3 HHJ40_RS04745 ENOG4108TC1 Transcriptional regulator HHJ40_RS04750 ENOG4105ISV protein with bipartite regulator domain HHJ40_RS04760 ENOG4105CHU acetyl-coa acetyltransferase HHJ40_RS04770 ENOG4105CHR reductase HHJ40_RS04775 ENOG4107QNK )-transporter HHJ40_RS04785 ENOG4105RQF LysR family Transcriptional regulator HHJ40_RS04795 ENOG41060NJ transcriptional regulator HHJ40_RS04805 ENOG4107S74 Lysophospholipid transporter LplT HHJ40_RS04810 ENOG4105CPC Aldo Keto reductase HHJ40_RS04815 ENOG4105SUV lipoprotein YgdR HHJ40_RS04820 ENOG4105EE5 Membrane protein terC HHJ40_RS04835 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HHJ40_RS04850 ENOG4105IPU prepilin peptidase dependent protein A HHJ40_RS04855 ENOG4105JCS prepilin peptidase dependent protein HHJ40_RS04860 ENOG4105SEN Protein of unknown function (DUF2509) HHJ40_RS04870 ENOG4105DSY exodeoxyribonuclease V, gamma HHJ40_RS04875 ENOG4107QXK peptidase HHJ40_RS04880 ENOG4107QKA exodeoxyribonuclease V beta HHJ40_RS04885 ENOG4107QYX exodeoxyribonuclease v alpha HHJ40_RS04890 ENOG4108EKC n-acetylglutamate synthase HHJ40_RS04895 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ40_RS04980 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ40_RS04990 ENOG4108ZG0 Ompa motb domain protein HHJ40_RS05025 ENOG4105CA3 membrane-bound lytic murein transglycosylase HHJ40_RS05030 ENOG4105CUZ uba thif-type nad fad binding protein HHJ40_RS05035 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HHJ40_RS05040 ENOG4105C9B Cysteine desulfurase HHJ40_RS05045 ENOG4105M5B (LipO)protein HHJ40_RS05050 ENOG4105ETT transcriptional Regulator, LysR family HHJ40_RS05055 ENOG4105M08 Membrane HHJ40_RS05065 ENOG4107EDW L-fucose operon activator HHJ40_RS05075 ENOG4105CMG Carbohydrate kinase HHJ40_RS05080 ENOG4105EHF Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity) HHJ40_RS05085 ENOG4105EDR glucose galactose transporter HHJ40_RS05090 ENOG4107W7X Aldolase HHJ40_RS05095 ENOG4105C0A alcohol dehydrogenase HHJ40_RS05105 ENOG4105EJQ L-serine dehydratase HHJ40_RS05110 ENOG4105C44 Serine transporter HHJ40_RS05115 ENOG4105EWT decarboxylase family HHJ40_RS05130 ENOG4105WP7 tRNA pseudouridine synthase C HHJ40_RS05135 ENOG4105DR9 pseudouridine synthase HHJ40_RS05140 ENOG4105QDK Flavodoxin HHJ40_RS05145 ENOG4105DJB Major Facilitator Superfamily HHJ40_RS05150 ENOG4105EQX glucarate dehydratase HHJ40_RS05155 ENOG4105EQX glucarate dehydratase HHJ40_RS05160 ENOG4105BZU Histidine kinase HHJ40_RS05165 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) HHJ40_RS05170 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ40_RS05175 ENOG4106A2Z transcriptional regulator antitoxin, MazE HHJ40_RS05180 ENOG4105MZG transcriptional modulator of maze toxin, mazf HHJ40_RS05185 ENOG4105DXN mazG family HHJ40_RS05200 ENOG4105HA9 of methanol dehydrogenase type HHJ40_RS05210 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HHJ40_RS05215 ENOG4108CWB sugar kinase ygcE HHJ40_RS05225 ENOG4105CHR reductase HHJ40_RS05230 ENOG4107R3A FAD linked oxidase domain protein HHJ40_RS05235 ENOG4105C54 Major Facilitator superfamily HHJ40_RS05240 ENOG4106IKH Electron transfer flavoprotein HHJ40_RS05245 ENOG4105YBM electron transfer flavoprotein subunit ygcQ HHJ40_RS05250 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator HHJ40_RS05255 ENOG4105WQV ferredoxin-like protein HHJ40_RS05260 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ40_RS05265 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HHJ40_RS05285 ENOG4107635 Hok Gef family protein HHJ40_RS05290 ENOG4105DTT CRISPR-associated helicase, cas3 HHJ40_RS05295 ENOG4105CYR Crispr-associated protein, cse1 family HHJ40_RS05305 ENOG41060M0 Crispr-associated protein, cse4 family HHJ40_RS05310 ENOG4108VWQ crispr-associated protein HHJ40_RS05320 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HHJ40_RS05325 ENOG4105PWE CRISPR-associated protein cas2 HHJ40_RS05330 ENOG4108MXK alkaline phosphatase isozyme conversion HHJ40_RS05335 ENOG4105C11 sulfate adenylyltransferase), subunit 2 HHJ40_RS05350 ENOG4105N0Z inner membrane protein ygbE HHJ40_RS05385 ENOG4108K5P (LipO)protein HHJ40_RS05390 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ40_RS05400 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HHJ40_RS05405 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HHJ40_RS05410 ENOG4105KZM cytoplasmic protein HHJ40_RS05415 ENOG4105C6Z Gluconate HHJ40_RS05420 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ40_RS05425 ENOG4105FB2 class II Aldolase HHJ40_RS05430 ENOG4105G63 Type III effector Hrp-dependent HHJ40_RS05435 ENOG4105ZXK Dehydrogenase HHJ40_RS05440 ENOG4105MVE transcriptional regulator HHJ40_RS05445 ENOG4105MEW serine threonine protein phosphatase HHJ40_RS05460 ENOG4105VXR cytoplasmic protein HHJ40_RS05465 ENOG4108JUA Transcriptional regulator HHJ40_RS05470 ENOG4105C45 hydrogenase expression formation protein (HypE) HHJ40_RS05475 ENOG4105CQS hydrogenase expression formation protein HypD HHJ40_RS05480 ENOG41083WG hydrogenase assembly chaperone HHJ40_RS05485 ENOG4107RSS Hydrogenase accessory protein HypB HHJ40_RS05490 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HHJ40_RS05495 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HHJ40_RS05500 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HHJ40_RS05505 ENOG4107R30 NADH dehydrogenase HHJ40_RS05510 ENOG4107TDF Formate hydrogenlyase subunit 4 HHJ40_RS05515 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HHJ40_RS05520 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HHJ40_RS05525 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HHJ40_RS05530 ENOG4105I6X formate hydrogenlyase maturation HHJ40_RS05535 ENOG4108MG9 hydrogenase 3 maturation protease HHJ40_RS05545 ENOG4105CS2 ec 3.2.1.21 HHJ40_RS05550 ENOG4105C5Y PTS System HHJ40_RS05555 ENOG4105DDV Transcriptional regulator (LacI family HHJ40_RS05560 ENOG4108RC0 Electron transport protein HHJ40_RS05565 ENOG4105C8H hydrogenase maturation protein Hypf HHJ40_RS05590 ENOG410804X Transcriptional regulator HHJ40_RS05595 ENOG4105J92 DNA-binding transcriptional activator GutM HHJ40_RS05600 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HHJ40_RS05605 ENOG4105VI0 Pts system, glucitol sorbitol-specific HHJ40_RS05610 ENOG4105DZY Pts system, glucitol sorbitol-specific HHJ40_RS05615 ENOG410787A Pts system, glucitol sorbitol-specific HHJ40_RS05620 ENOG4105CVE Lytic murein transglycosylase HHJ40_RS05625 ENOG4107TH8 cina domain protein HHJ40_RS05645 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HHJ40_RS05670 ENOG4107VXZ Hydrolase HHJ40_RS05675 ENOG4105W39 Membrane HHJ40_RS05690 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ40_RS05695 ENOG4105CW7 secretion protein, HlyD family HHJ40_RS05700 ENOG4105NTK Transcriptional repressor Mpra HHJ40_RS05710 ENOG4105ZED uncharacterized protein ygaH HHJ40_RS05715 ENOG4108UMN azlc family HHJ40_RS05725 ENOG4105GIJ Glycine betaine HHJ40_RS05730 ENOG4108HQS Glycine betaine HHJ40_RS05735 ENOG4108IJ7 Glycine betaine HHJ40_RS05740 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ40_RS05745 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ40_RS05755 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HHJ40_RS05760 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HHJ40_RS05765 ENOG4108WMJ Protein of unknown function (DUF2002) HHJ40_RS05770 ENOG4108RNS Exports L-alanine (By similarity) HHJ40_RS05775 ENOG4108X73 DNA- binding protein HHJ40_RS05780 ENOG4108V62 Rhodanese domain protein HHJ40_RS05785 ENOG41080HT Transcriptional regulator, arsr family HHJ40_RS05790 ENOG4105VPI YqaE family transport protein HHJ40_RS05795 ENOG4109066 lysm domain bon superfamily protein HHJ40_RS05800 ENOG4108PVQ transcriptional regulator HHJ40_RS05805 ENOG4105C85 amino acid HHJ40_RS05810 ENOG4108JPW Aminotransferase HHJ40_RS05815 ENOG4105C26 Dehydrogenase HHJ40_RS05820 ENOG4105D5U fad dependent oxidoreductase HHJ40_RS05855 ENOG4105DFP Integrase HHJ40_RS05870 ENOG4108Z1B Cyclase dehydrase HHJ40_RS05880 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ40_RS05885 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HHJ40_RS05905 ENOG4108JU6 CBS domain protein HHJ40_RS05910 ENOG4106KVJ cytochrome C assembly protein HHJ40_RS05915 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HHJ40_RS05940 ENOG41090EK ompa motb domain protein HHJ40_RS05945 ENOG4108KHX Diguanylate cyclase HHJ40_RS05950 ENOG4108WS1 HHJ40_RS05955 ENOG4105QP9 Protein of unknown function (DUF2799) HHJ40_RS05960 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ40_RS05965 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HHJ40_RS05970 ENOG4105CQC Prephenate dehydratase HHJ40_RS05980 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HHJ40_RS05985 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HHJ40_RS05990 ENOG4105C34 Pseudouridine synthase HHJ40_RS05995 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HHJ40_RS06000 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ40_RS06025 ENOG4105CSH Transporter HHJ40_RS06030 ENOG4105T42 (LipO)protein HHJ40_RS06035 ENOG4105JIM Phosphatidylserine synthase HHJ40_RS06040 ENOG4105CD5 CoA-binding domain protein HHJ40_RS06045 ENOG4106IUH DTW domain containing protein HHJ40_RS06050 ENOG4105K63 Thioredoxin HHJ40_RS06055 ENOG4105EIB trna rrna methyltransferase HHJ40_RS06075 ENOG41090KR LysR family transcriptional Regulator HHJ40_RS06080 ENOG4105C1J atp-dependent rna helicase HHJ40_RS06090 ENOG4108IYU L-aspartate oxidase HHJ40_RS06100 ENOG4105EMN RNA polymerase sigma factor HHJ40_RS06105 ENOG41069PW sigma-e factor negative regulatory protein HHJ40_RS06110 ENOG4105VQK sigma E regulatory protein, MucB RseB HHJ40_RS06115 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HHJ40_RS06125 ENOG4105C3F Signal peptidase i HHJ40_RS06145 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HHJ40_RS06160 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HHJ40_RS06165 ENOG4106G6Q Transcriptional regulator HHJ40_RS06170 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HHJ40_RS06175 ENOG4108Z6B deaminase HHJ40_RS06190 ENOG4107WP9 Histidine kinase HHJ40_RS06195 ENOG4108SKK alpha helix protein HHJ40_RS06200 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ40_RS06210 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ40_RS06220 ENOG4108NZE NAGC-like transcriptional regulator HHJ40_RS06225 ENOG4107HQ7 repeat protein HHJ40_RS06230 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HHJ40_RS06235 ENOG4108F37 ATP-binding component of a transport system HHJ40_RS06240 ENOG4105CNN ABC, transporter HHJ40_RS06245 ENOG4105CPQ Dehydrogenase HHJ40_RS06250 ENOG4108ZKT aldose 1-epimerase HHJ40_RS06255 ENOG4108SB3 DoxX Family HHJ40_RS06280 ENOG4105FUY alpha subunit HHJ40_RS06285 ENOG4108W5M transcriptional regulator HHJ40_RS06290 ENOG4105D8G Major Facilitator superfamily HHJ40_RS06295 ENOG4108MN2 Stationary phase inducible protein CsiE HHJ40_RS06300 ENOG4107XM9 (LipO)protein HHJ40_RS06305 ENOG4105ECY inositol monophosphatase HHJ40_RS06325 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HHJ40_RS06345 ENOG4108ZIT Ferredoxin, 2FE-2S HHJ40_RS06350 ENOG4105WVQ Fe-S assembly protein IscX HHJ40_RS06360 ENOG4105YYA enhanced serine sensitivity protein SseB HHJ40_RS06365 ENOG4105KHC sulfurtransferase HHJ40_RS06370 ENOG4105DN3 alpha-2-macroglobulin domain protein HHJ40_RS06375 ENOG4108JQB penicillin-binding protein 1C HHJ40_RS06405 ENOG4105N21 Membrane HHJ40_RS06420 ENOG4105VPD cellular component movement HHJ40_RS06430 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HHJ40_RS06440 ENOG41066DY Membrane HHJ40_RS06445 ENOG4108ZMA Outer membrane lipoprotein HHJ40_RS06450 ENOG41062G3 Protein of unknown function (DUF2633) HHJ40_RS06460 ENOG4105BZU Histidine kinase HHJ40_RS06465 ENOG4105C9X ppx gppa phosphatase HHJ40_RS06470 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HHJ40_RS06475 ENOG4108V3E phosphoribosylglycinamide formyltransferase HHJ40_RS06490 ENOG4105C2W permease HHJ40_RS06495 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HHJ40_RS06500 ENOG4105K89 arsenate reductase HHJ40_RS06505 ENOG4105ERG peptidase m48, ste24p HHJ40_RS06510 ENOG4105C02 permease HHJ40_RS06515 ENOG4105TMB Formate nitrite transporter HHJ40_RS06520 ENOG4108JUA Transcriptional regulator HHJ40_RS06525 ENOG4105I6X formate hydrogenlyase maturation HHJ40_RS06540 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HHJ40_RS06545 ENOG4108JPZ Monovalent cation H antiporter subunit D HHJ40_RS06550 ENOG4107WQX hydrogenase 4 membrane subunit HHJ40_RS06560 ENOG4105D65 subunit l HHJ40_RS06565 ENOG4107TDF Formate hydrogenlyase subunit 4 HHJ40_RS06570 ENOG4108JPZ Monovalent cation H antiporter subunit D HHJ40_RS06575 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HHJ40_RS06580 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HHJ40_RS06585 ENOG4105RH4 Glycine cleavage system transcriptional repressor HHJ40_RS06595 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ40_RS06610 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A HHJ40_RS06615 ENOG4105CGZ zinc metallopeptidase HHJ40_RS06625 ENOG4106KED esterase YpfH HHJ40_RS06640 ENOG4105KUZ arsenate reductase HHJ40_RS06650 ENOG4105BZS acriflavin resistance protein HHJ40_RS06655 ENOG4105BZU Histidine kinase HHJ40_RS06660 ENOG4105BZ8 glutamate synthase HHJ40_RS06670 ENOG4108PVD exported protein HHJ40_RS06675 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ40_RS06680 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ40_RS06685 ENOG4105C6K Malic enzyme HHJ40_RS06690 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HHJ40_RS06695 ENOG4106S4J ethanolamine utilization protein EutP HHJ40_RS06700 ENOG4105NDK ethanolamine utilization protein HHJ40_RS06705 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HHJ40_RS06710 ENOG4107WUY phosphate acetyltransferase HHJ40_RS06715 ENOG4105KNY Microcompartments protein HHJ40_RS06720 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HHJ40_RS06725 ENOG4108EKI Dehydrogenase HHJ40_RS06730 ENOG4107RWI ethanolamine utilization protein eutJ HHJ40_RS06735 ENOG4105C0A alcohol dehydrogenase HHJ40_RS06740 ENOG4105ENY Ethanolamine utilization protein eutH HHJ40_RS06745 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HHJ40_RS06750 ENOG4105CPD ethanolamine ammonia-lyase HHJ40_RS06765 ENOG4108X49 Ethanolamine utilization protein EutK HHJ40_RS06770 ENOG4108K3Z AraC family transcriptional regulator HHJ40_RS06780 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HHJ40_RS06790 ENOG4105QZU Inner membrane protein YfeZ HHJ40_RS06795 ENOG4105E7K (LipO)protein HHJ40_RS06800 ENOG4105EZR dyp-type peroxidase family protein HHJ40_RS06805 ENOG4107S1E Beta-lactamase HHJ40_RS06810 ENOG4105C5Y PTS System HHJ40_RS06825 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HHJ40_RS06830 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HHJ40_RS06835 ENOG4108I5D sulfate abc transporter HHJ40_RS06840 ENOG4105ECW sulfate abc transporter HHJ40_RS06845 ENOG4108IJ6 ABC transporter HHJ40_RS06850 ENOG4105C6T cysteine synthase HHJ40_RS06855 ENOG4105M0Y HHJ40_RS06865 ENOG4105C5Y PTS System HHJ40_RS06870 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ40_RS06880 ENOG4105C6T cysteine synthase HHJ40_RS06900 ENOG4105VRT cytoplasmic protein HHJ40_RS06905 ENOG4105DHU Bile acid HHJ40_RS06910 ENOG4108M0I Transcriptional regulator HHJ40_RS06950 ENOG4105GXM Putative transcription regulator (DUF1323) HHJ40_RS06955 ENOG4105HZG regulatoR HHJ40_RS06970 ENOG4108KMM Diguanylate cyclase HHJ40_RS06975 ENOG4105D9N nucleoside HHJ40_RS06985 ENOG4109076 Conserved Protein HHJ40_RS07000 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ40_RS07005 ENOG410863U PTS System HHJ40_RS07010 ENOG4105DC7 peptidase M24 HHJ40_RS07015 ENOG4105CN9 Peptidase m42 family protein HHJ40_RS07020 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ40_RS07025 ENOG4108CIP transcriptional regulator HHJ40_RS07030 ENOG4105DY9 regulatoR HHJ40_RS07035 ENOG4108HRK Histidine kinase HHJ40_RS07040 ENOG4105CHM Aminotransferase HHJ40_RS07050 ENOG4105D1S lipid A biosynthesis HHJ40_RS07055 ENOG4105W9M Membrane HHJ40_RS07065 ENOG4108V08 YfdX protein HHJ40_RS07075 ENOG4105CFN oxalyl-CoA decarboxylase HHJ40_RS07080 ENOG4108N2Y auxin Efflux HHJ40_RS07085 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HHJ40_RS07090 ENOG4105BZU Histidine kinase HHJ40_RS07095 ENOG4108WQH regulatoR HHJ40_RS07100 ENOG4105CW7 secretion protein, HlyD family HHJ40_RS07105 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ40_RS07120 ENOG4106NDP Transcriptional regulator HHJ40_RS07125 ENOG4108HKT sucrose-6-phosphate hydrolase HHJ40_RS07130 ENOG4105D7K pfkb domain protein HHJ40_RS07135 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HHJ40_RS07145 ENOG4105S64 Formate nitrite transporter HHJ40_RS07150 ENOG410903C (LipO)protein HHJ40_RS07160 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HHJ40_RS07165 ENOG4105KZW UPF0381 protein HHJ40_RS07180 ENOG4108BY2 phosphohistidine phosphatase HHJ40_RS07190 ENOG4106PG1 outer membrane usher protein HHJ40_RS07195 ENOG4108FZ9 Chaperone HHJ40_RS07200 ENOG4105NEV Fimbrial HHJ40_RS07205 ENOG4105UGQ Fimbrial HHJ40_RS07210 ENOG4105US4 fimbrial-like protein yfcP HHJ40_RS07240 ENOG4105EJ9 Membrane HHJ40_RS07245 ENOG4108BPE -transporting atpase HHJ40_RS07250 ENOG4105MH2 YfcL protein HHJ40_RS07255 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) HHJ40_RS07260 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ40_RS07265 ENOG4105F9N Major Facilitator Superfamily HHJ40_RS07270 ENOG4106WZ1 flagella biosynthesis regulator HHJ40_RS07330 ENOG4108C33 Resolvase HHJ40_RS07345 ENOG4105UZW Tail fiber assembly protein HHJ40_RS07350 ENOG4108X9F tail fiber protein HHJ40_RS07350 ENOG4108X9F tail fiber protein HHJ40_RS07430 ENOG4105ED4 portal protein HHJ40_RS07515 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HHJ40_RS07525 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ40_RS07535 ENOG4105DQR SNARE associated Golgi HHJ40_RS07545 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HHJ40_RS07550 ENOG4108S3P Sporulation domain protein HHJ40_RS07555 ENOG4105E96 Colicin v production protein HHJ40_RS07560 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HHJ40_RS07565 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HHJ40_RS07570 ENOG4105E89 ABC transporter HHJ40_RS07575 ENOG4105E89 ABC transporter HHJ40_RS07580 ENOG4105DSP amino acid AbC transporter HHJ40_RS07585 ENOG4106YG3 ABC transporter HHJ40_RS07590 ENOG4108JEH abc transporter atp-binding protein HHJ40_RS07595 ENOG4105DNE Transposase HHJ40_RS07600 ENOG4105ECP epimerase HHJ40_RS07605 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HHJ40_RS07610 ENOG4105CYM Glutathione S-transferase HHJ40_RS07615 ENOG4108SHQ Glutathione S-transferase HHJ40_RS07620 ENOG4108RE9 Phosphodiesterase HHJ40_RS07625 ENOG4105PTV Nudix Hydrolase HHJ40_RS07630 ENOG4105CSX c4-dicarboxylate anaerobic carrier HHJ40_RS07635 ENOG4105C6K Malic enzyme HHJ40_RS07640 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HHJ40_RS07650 ENOG4105XWI UPF0304 protein HHJ40_RS07655 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HHJ40_RS07660 ENOG4107QWE )-transporter HHJ40_RS07670 ENOG4105CHM Aminotransferase HHJ40_RS07675 ENOG4107NQ8 LysR family Transcriptional regulator HHJ40_RS07695 ENOG4105GKE subunit e HHJ40_RS07700 ENOG4107QIZ NADH dehydrogenase HHJ40_RS07705 ENOG4108IEH NADH dehydrogenase subunit g HHJ40_RS07720 ENOG4107UFS subunit j HHJ40_RS07730 ENOG4105D65 subunit l HHJ40_RS07735 ENOG4105C8S subunit m HHJ40_RS07745 ENOG4105GDX Domain of unknown function (DUF1877) HHJ40_RS07765 ENOG4107YB6 acetyltransferase, (GNAT) family HHJ40_RS07770 ENOG4105TNS Conserved Protein HHJ40_RS07775 ENOG4105E4F Isochorismate synthase HHJ40_RS07790 ENOG4108IPT Naphthoate synthase HHJ40_RS07800 ENOG4105CEY Amp-dependent synthetase and ligase HHJ40_RS07805 ENOG4106GZG polymyxin resistance protein B HHJ40_RS07810 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) HHJ40_RS07855 ENOG4108UII YfaZ family HHJ40_RS07870 ENOG4105DNE Transposase HHJ40_RS07875 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ40_RS07885 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HHJ40_RS07890 ENOG4105CXY transporter HHJ40_RS07895 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HHJ40_RS07905 ENOG4105FQR PH-inducible protein involved in stress response HHJ40_RS07910 ENOG4105XPH Ferredoxin HHJ40_RS07915 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ40_RS07920 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ40_RS07925 ENOG4107GHC outer membrane autotransporter HHJ40_RS07935 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ40_RS07940 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HHJ40_RS07945 ENOG4108QJJ Protein of unknown function (DUF1175) HHJ40_RS07950 ENOG4107S52 alpha-2-macroglobulin domain protein HHJ40_RS07955 ENOG41081SK signal peptide protein HHJ40_RS07960 ENOG4105EDV vault protein HHJ40_RS07965 ENOG4105BZU Histidine kinase HHJ40_RS07970 ENOG41068CG regulatoR HHJ40_RS07975 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HHJ40_RS07980 ENOG4105FCK Membrane HHJ40_RS07985 ENOG4105CJ2 (LipO)protein HHJ40_RS07990 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ40_RS07995 ENOG4105CF1 Alkylated DNA repair protein HHJ40_RS08000 ENOG4105IBP Cyclic peptide transporter HHJ40_RS08015 ENOG4108ZNS ferredoxin-type protein NapF HHJ40_RS08020 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HHJ40_RS08030 ENOG4108BGM Quinol dehydrogenase periplasmic component HHJ40_RS08035 ENOG4105GXZ Ferredoxin-type protein NapH HHJ40_RS08040 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HHJ40_RS08045 ENOG4105CUW cytochrome C-TYPE protein HHJ40_RS08050 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HHJ40_RS08055 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HHJ40_RS08060 ENOG41060IM Heme exporter protein HHJ40_RS08065 ENOG4105X3C heme exporter protein HHJ40_RS08075 ENOG4105DA4 cytochrome c-type biogenesis protein HHJ40_RS08080 ENOG4107QX9 Thiol disulfide interChange protein HHJ40_RS08085 ENOG4105KWW Biogenesis protein HHJ40_RS08090 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ40_RS08105 ENOG4105E68 Sulfatase HHJ40_RS08125 ENOG4105CFI type iii restriction protein res subunit HHJ40_RS08130 ENOG4105I08 Pseudouridine synthase HHJ40_RS08135 ENOG4105C2C drug resistance transporter, Bcr CflA HHJ40_RS08140 ENOG4105HG6 HHJ40_RS08145 ENOG4108JQ5 ABC transporter HHJ40_RS08150 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HHJ40_RS08155 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HHJ40_RS08160 ENOG4105E43 Extracellular solute-binding protein, family 5 HHJ40_RS08165 ENOG4105CXC rtn protein HHJ40_RS08170 ENOG4107TT5 NLP P60 protein HHJ40_RS08175 ENOG41076MN Phosphoesterase, PA-phosphatase related HHJ40_RS08180 ENOG4105CKI cobalamin synthesis protein HHJ40_RS08185 ENOG4105DEI Mannitol dehydrogenase HHJ40_RS08195 ENOG4105KRS Proteinase inhibitor HHJ40_RS08200 ENOG4105S8Q sugar efflux transporter HHJ40_RS08205 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HHJ40_RS08210 ENOG4105DE4 1-phosphofructokinase HHJ40_RS08215 ENOG4105DM4 PTS System HHJ40_RS08220 ENOG4105DD7 kinase (PfkB family HHJ40_RS08225 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HHJ40_RS08230 ENOG4105D9N nucleoside HHJ40_RS08235 ENOG4108Y4K DNA-binding transcriptional activator HHJ40_RS08245 ENOG4105D9N nucleoside HHJ40_RS08250 ENOG4105DD7 kinase (PfkB family HHJ40_RS08260 ENOG4105HMI Membrane HHJ40_RS08265 ENOG4105DUM transcriptional regulator, lysR family HHJ40_RS08270 ENOG4108IQI permease HHJ40_RS08275 ENOG4105D05 Receptor HHJ40_RS08290 ENOG4105DHF Membrane HHJ40_RS08295 ENOG41060NJ transcriptional regulator HHJ40_RS08300 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HHJ40_RS08305 ENOG4105C2J ABC transporter HHJ40_RS08310 ENOG4108HWV )-transporter HHJ40_RS08315 ENOG4107SJI Dehydrogenase HHJ40_RS08320 ENOG4105BZ8 glutamate synthase HHJ40_RS08325 ENOG4105Y9N Membrane HHJ40_RS08330 ENOG4107GZ4 SanA protein HHJ40_RS08340 ENOG41067MG lrgb family HHJ40_RS08350 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HHJ40_RS08360 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ40_RS08365 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HHJ40_RS08370 ENOG4105KHU inner membrane protein YohD HHJ40_RS08375 ENOG41069YE inner membrane protein yohC HHJ40_RS08380 ENOG41061WM D-Alanyl-D-Alanine HHJ40_RS08385 ENOG4105CXG d-lactate dehydrogenase HHJ40_RS08390 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HHJ40_RS08395 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HHJ40_RS08400 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HHJ40_RS08405 ENOG4108IJ8 ABC transporter HHJ40_RS08410 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HHJ40_RS08420 ENOG4108XDN Transcriptional regulator HHJ40_RS08425 ENOG4108HRK Histidine kinase HHJ40_RS08430 ENOG4108NEV two component transcriptional regulator, LytTR family HHJ40_RS08435 ENOG4108W15 Protein of unknown function (DUF1456) HHJ40_RS08440 ENOG4108YCW (LipO)protein HHJ40_RS08445 ENOG410903U zinc ion binding HHJ40_RS08450 ENOG4105DEG Vwa containing coxe family protein HHJ40_RS08455 ENOG4105RD5 HHJ40_RS08460 ENOG4105KKX ATPase associated with various cellular activities aaa_5 HHJ40_RS08470 ENOG4108KDT Molybdate metabolism regulator HHJ40_RS08475 ENOG4108KDT Molybdate metabolism regulator HHJ40_RS08485 ENOG4105D1F ATP-binding protein HHJ40_RS08490 ENOG41067AK Protein of unknown function (DUF2574) HHJ40_RS08495 ENOG41063W2 Fimbrial protein HHJ40_RS08500 ENOG4108MQF Chaperone HHJ40_RS08505 ENOG4105CW0 outer membrane usher protein HHJ40_RS08510 ENOG410662B Type-1 fimbrial protein HHJ40_RS08515 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HHJ40_RS08535 ENOG4105DWF phosphomethylpyrimidine kinase HHJ40_RS08540 ENOG4108UQ1 hydrolase, family 25 HHJ40_RS08545 ENOG4105FDP GntR family transcriptional regulator HHJ40_RS08550 ENOG4108TFM Kinase, PfkB family HHJ40_RS08555 ENOG4108KD5 ADP-ribosylation crystallin J1 HHJ40_RS08560 ENOG4105EAA nucleoside HHJ40_RS08565 ENOG4105EIE fructose-bisphosphate aldolase HHJ40_RS08580 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HHJ40_RS08585 ENOG41090UW PTS System HHJ40_RS08590 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ40_RS08595 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HHJ40_RS08610 ENOG41076Z6 Uncharacterized protein yegR HHJ40_RS08615 ENOG4105CFP Peptidase U32 HHJ40_RS08625 ENOG4105X54 addiction module antidote protein HHJ40_RS08630 ENOG4105KWI UPF0339 protein HHJ40_RS08635 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ40_RS08640 ENOG4105EB3 Histidine kinase HHJ40_RS08680 ENOG4108M24 von Willebrand factor, type A HHJ40_RS08685 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HHJ40_RS08690 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding HHJ40_RS08695 ENOG4105R8A Heat shock protein HHJ40_RS08700 ENOG4105D03 DNA-3-methyladenine glycosylase II HHJ40_RS08705 ENOG4105BZU Histidine kinase HHJ40_RS08710 ENOG4105DBI uridine monophosphokinase HHJ40_RS08720 ENOG4108GAE asmA family HHJ40_RS08735 ENOG4105DAY polysaccharide export protein HHJ40_RS08740 ENOG4105KJF protein tyrosine phosphatase HHJ40_RS08745 ENOG4105D75 Capsular exopolysaccharide family HHJ40_RS08750 ENOG41090RK glycosyl transferase HHJ40_RS08755 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HHJ40_RS08760 ENOG4107RXY Glycosyl transferase HHJ40_RS08765 ENOG4108NYJ Colanic acid HHJ40_RS08770 ENOG4105ECJ Glycosyl Transferase HHJ40_RS08775 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HHJ40_RS08780 ENOG4105C0K Gdp-mannose 4,6-dehydratase HHJ40_RS08785 ENOG4105C30 Nad-dependent epimerase dehydratase HHJ40_RS08790 ENOG4105FGF GDP-mannose mannosyl hydrolase HHJ40_RS08795 ENOG4106CD9 glycosyl transferase group 1 HHJ40_RS08800 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HHJ40_RS08805 ENOG4107QKV phosphomannomutase HHJ40_RS08810 ENOG4105D3Q Sugar transferase HHJ40_RS08815 ENOG4105PSV Polysaccharide Biosynthesis Protein HHJ40_RS08820 ENOG4105C74 pyruvyl transferase HHJ40_RS08825 ENOG4107T8Q Glycosyl transferase (Group 1 HHJ40_RS08830 ENOG4105G1A colanic acid biosynthesis protein HHJ40_RS08835 ENOG4105DMT epimerase dehydratase HHJ40_RS08840 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ40_RS08850 ENOG4105D2T synthase HHJ40_RS08890 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HHJ40_RS08895 ENOG4105C6Y Udp-glucose 6-dehydrogenase HHJ40_RS08900 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HHJ40_RS08905 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase HHJ40_RS08920 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HHJ40_RS08925 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HHJ40_RS08935 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) HHJ40_RS08950 ENOG4107SRH Nad-dependent epimerase dehydratase HHJ40_RS08955 ENOG4105EQ1 Transcriptional regulator HHJ40_RS08965 ENOG4105CUB amino acid HHJ40_RS08970 ENOG4105CUC YeeE YedE family protein HHJ40_RS08980 ENOG4105CJB Exodeoxyribonuclease I HHJ40_RS08985 ENOG4105DZ1 carboxypeptidase HHJ40_RS08995 ENOG4105DR8 Membrane HHJ40_RS09010 ENOG4108YZT Adenosylcobinamide kinase HHJ40_RS09025 ENOG4108PXI ErfK YbiS YcfS YnhG HHJ40_RS09035 ENOG4106P55 Transcriptional regulator HHJ40_RS09040 ENOG4107R11 Transcriptional regulator HHJ40_RS09065 ENOG4105FYV Amp nucleosidase HHJ40_RS09070 ENOG4105CSH Transporter HHJ40_RS09100 ENOG4108VKM cytochrome b561 HHJ40_RS09105 ENOG4108MEK Metal-binding protein YodA HHJ40_RS09120 ENOG4105VT2 5-hydroxyisourate hydrolase HHJ40_RS09125 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ40_RS09130 ENOG4107ZY3 Histidine kinase HHJ40_RS09140 ENOG4105ZIT Porin Gram-negative type HHJ40_RS09145 ENOG4105Y0K Inner membrane protein YedR HHJ40_RS09150 ENOG4105EST Metal Dependent Phosphohydrolase HHJ40_RS09155 ENOG4105DVF Cytosine-specific methyltransferase HHJ40_RS09160 ENOG41090BB DNA mismatch endonuclease (vsr) HHJ40_RS09165 ENOG4105FDR Membrane HHJ40_RS09170 ENOG4105CKW Inner membrane protein yedI HHJ40_RS09175 ENOG4105VNZ cytoplasmic protein HHJ40_RS09190 ENOG4105YX3 cellular response to acidity HHJ40_RS09200 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HHJ40_RS09205 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HHJ40_RS09215 ENOG4105CN7 Flagellar biosynthetic protein FliP HHJ40_RS09220 ENOG4105K0P flagellar biosynthesis protein HHJ40_RS09225 ENOG4105DD5 Flagellar motor switch protein HHJ40_RS09230 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ40_RS09235 ENOG4107ZI8 flagellar basal body-associated protein flil HHJ40_RS09240 ENOG4105WF4 Flagellar hook-length control protein HHJ40_RS09245 ENOG4105GSA Flagellar export protein flij HHJ40_RS09250 ENOG4108JIR Flagellum-specific ATP synthase HHJ40_RS09255 ENOG41090PJ Flagellar assembly protein HHJ40_RS09260 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ40_RS09265 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HHJ40_RS09270 ENOG4105VQ0 flagellar hook-basal body complex protein fliE HHJ40_RS09275 ENOG4108RAV Conserved protein HHJ40_RS09285 ENOG41066VF YeeE YedE family protein HHJ40_RS09290 ENOG4108W9D (LipO)protein HHJ40_RS09295 ENOG4105E5K Alpha-amylase HHJ40_RS09300 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) HHJ40_RS09305 ENOG4105MQ3 flagellar protein FliS HHJ40_RS09310 ENOG4105DTS flagellar hook-associated HHJ40_RS09315 ENOG4105I03 Flagellin HHJ40_RS09320 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ40_RS09325 ENOG4108M9K flagella biosynthesis protein FliZ HHJ40_RS09330 ENOG4105EAB amino acid AbC transporter HHJ40_RS09335 ENOG4105K6H D-cysteine desulfhydrase HHJ40_RS09340 ENOG4105E5Q amino acid AbC transporter HHJ40_RS09345 ENOG4105CDA abc transporter atp-binding protein HHJ40_RS09350 ENOG4105VJY transcriptional regulator HHJ40_RS09355 ENOG4105XVG cytoplasmic protein HHJ40_RS09365 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ40_RS09395 ENOG4106RHG Yeca family HHJ40_RS09400 ENOG4105E0U tyrosine-specific transport protein HHJ40_RS09405 ENOG4105VVZ metal-binding protein HHJ40_RS09410 ENOG41090A1 ferritin HHJ40_RS09415 ENOG4105P23 (LipO)protein HHJ40_RS09425 ENOG4105N4N Protein of unknown function (DUF2766) HHJ40_RS09430 ENOG4108UEC Ferritin-like protein HHJ40_RS09435 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HHJ40_RS09440 ENOG4105C2J ABC transporter HHJ40_RS09445 ENOG4105CNN ABC, transporter HHJ40_RS09450 ENOG4108K4C ec 3.1.3.12 HHJ40_RS09460 ENOG4108VA4 Universal stress protein HHJ40_RS09470 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HHJ40_RS09475 ENOG4107RD7 Flagellar Motor Protein, MotA HHJ40_RS09480 ENOG4105ER2 Ompa motb domain protein HHJ40_RS09485 ENOG4105CBS Chea signal transduction histidine kinase HHJ40_RS09490 ENOG4108V3W Chemotaxis protein, CheW HHJ40_RS09495 ENOG4105C8Q Methyl-accepting chemotaxis HHJ40_RS09500 ENOG4105C8Q Methyl-accepting chemotaxis HHJ40_RS09505 ENOG4105BZU Histidine kinase HHJ40_RS09510 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) HHJ40_RS09515 ENOG4108VYJ response regulator receiver protein HHJ40_RS09520 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HHJ40_RS09525 ENOG4105D00 flagellar biosynthetic protein flhB HHJ40_RS09530 ENOG4105D7B Flagellar biosynthesis protein flha HHJ40_RS09535 ENOG4105W13 flagellar protein HHJ40_RS09545 ENOG4105C75 arginyL-tRNA synthetase HHJ40_RS09550 ENOG4106ZCM YecM protein HHJ40_RS09560 ENOG4105CUW cytochrome C-TYPE protein HHJ40_RS09565 ENOG4108J2R molybdopterin oxidoreductase HHJ40_RS09580 ENOG4105WJG Glutathione HHJ40_RS09585 ENOG41081XQ Conserved Protein HHJ40_RS09590 ENOG4105D3W isochorismatase HHJ40_RS09600 ENOG4108TIT dATP pyrophosphohydrolase HHJ40_RS09605 ENOG4105CDY transcriptional regulatory protein HHJ40_RS09615 ENOG4107S01 Repressor protein MetJ HHJ40_RS09635 ENOG4105FAV ABC, transporter HHJ40_RS09645 ENOG4105NXV High-affinity zinc uptake system protein HHJ40_RS09650 ENOG4105DR5 peptidase HHJ40_RS09655 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HHJ40_RS09660 ENOG4105CA9 Pyruvate kinase HHJ40_RS09665 ENOG4106KNT transcriptional regulator HHJ40_RS09670 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HHJ40_RS09675 ENOG4105C01 Dihydroxy-acid dehydratase HHJ40_RS09680 ENOG4108UHU Aldolase HHJ40_RS09690 ENOG4105X2V dna damage-inducible protein HHJ40_RS09700 ENOG4108Q2J Inner membrane protein YebE HHJ40_RS09705 ENOG4105CUG Oligopeptidase b HHJ40_RS09710 ENOG4105UMD exodeoxyribonuclease X HHJ40_RS09715 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ40_RS09720 ENOG4105MPK DNA polymerase III subunit theta HHJ40_RS09725 ENOG4105FXM Copper resistance protein HHJ40_RS09730 ENOG4108PNC copper resistance HHJ40_RS09735 ENOG4105NKT exported protein HHJ40_RS09740 ENOG4108R1E Serine threonine protein phosphatase 1 HHJ40_RS09745 ENOG4105UVW uncharacterized protein yebW HHJ40_RS09750 ENOG4105WT8 Protein of unknown function (DUF1480) HHJ40_RS09760 ENOG4105DY2 Paraquat-inducible protein b HHJ40_RS09765 ENOG4105H2K paraquat-inducible protein a HHJ40_RS09770 ENOG4108ZGC gaf domain protein HHJ40_RS09780 ENOG4105CN1 protease HHJ40_RS09790 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ40_RS09795 ENOG4105J4Q Transcriptional regulator HHJ40_RS09800 ENOG4105TIK HHJ40_RS09810 ENOG4105Q3Y exported protein HHJ40_RS09825 ENOG4105DHI Methyltransferase HHJ40_RS09840 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ40_RS09845 ENOG4105ETZ PTS System HHJ40_RS09850 ENOG4105DAS pts system HHJ40_RS09855 ENOG4105EE5 Membrane protein terC HHJ40_RS09860 ENOG4107XTP (EAL) domain protein HHJ40_RS09865 ENOG4105EJQ L-serine dehydratase HHJ40_RS09875 ENOG4105CRQ synthase (Component I) HHJ40_RS09885 ENOG4105V2F Uncharacterized protein yoac HHJ40_RS09890 ENOG4105M4H endoribonuclease L-psp HHJ40_RS09895 ENOG4105DVT helicase HHJ40_RS09900 ENOG41072GX Peptidase M22 Glycoprotease HHJ40_RS09905 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ40_RS09910 ENOG4105CEY Amp-dependent synthetase and ligase HHJ40_RS09915 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HHJ40_RS09920 ENOG4105E3J oxidoreductase HHJ40_RS09925 ENOG4105DVW rieske (2Fe-2S) HHJ40_RS09930 ENOG4105C94 Transporter HHJ40_RS09935 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HHJ40_RS09940 ENOG4105EJC lysr family transcriptional regulator HHJ40_RS09950 ENOG4108YS1 cytoplasmic protein HHJ40_RS09955 ENOG4105YP6 Domain of unknown function (DUF1869) HHJ40_RS09965 ENOG4105D7V transposase HHJ40_RS09970 ENOG4105Y3U Transglycosylase-associated protein HHJ40_RS09980 ENOG4106G4W HHJ40_RS09985 ENOG410620I Diguanylate cyclase HHJ40_RS09990 ENOG4105UCG Domain of unknown function (DUF333) HHJ40_RS09995 ENOG4105K78 MarR family Transcriptional regulator HHJ40_RS10000 ENOG4105DJ2 Major Facilitator Superfamily HHJ40_RS10005 ENOG4105R1U AraC Family Transcriptional Regulator HHJ40_RS10025 ENOG4108KHP Diguanylate cyclase HHJ40_RS10030 ENOG4106KTS Inner membrane protein yeaI HHJ40_RS10040 ENOG4105CYN Serine protein kinase HHJ40_RS10045 ENOG4105GNX MltA-interacting MipA family protein HHJ40_RS10050 ENOG4105CV8 reductase HHJ40_RS10055 ENOG4105DSB aldose 1-epimerase HHJ40_RS10060 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ40_RS10070 ENOG4105VUT cytoplasmic protein HHJ40_RS10075 ENOG4105CPQ Dehydrogenase HHJ40_RS10080 ENOG4107TE1 transport protein HHJ40_RS10085 ENOG4105CPQ Dehydrogenase HHJ40_RS10090 ENOG4105D2N Aldolase HHJ40_RS10095 ENOG4107UH8 sugar kinase HHJ40_RS10100 ENOG4105CPC Aldo Keto reductase HHJ40_RS10105 ENOG4105E98 transcriptional regulator DeoR family HHJ40_RS10110 ENOG4108KUU Inner membrane metabolite transport protein ydjE HHJ40_RS10115 ENOG4108RWI nicotinamidase HHJ40_RS10120 ENOG4105HDK L-asparaginase HHJ40_RS10125 ENOG4105D07 Signal peptide peptidase, SppA HHJ40_RS10130 ENOG41069NU Nitroreductase HHJ40_RS10140 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ40_RS10145 ENOG41065FB inner membrane protein ynji HHJ40_RS10155 ENOG4105D82 Glutamate dehydrogenase HHJ40_RS10160 ENOG4105MTM Protein of unknown function (DUF1496) HHJ40_RS10165 ENOG4105M6F mutator MutT protein HHJ40_RS10170 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HHJ40_RS10175 ENOG4107RM6 sulfurtransferase HHJ40_RS10180 ENOG4108VGW abc transporter atp-binding protein HHJ40_RS10185 ENOG4105CXZ ABC transporter, permease HHJ40_RS10190 ENOG4105VNH ABC transporter solute-binding protein HHJ40_RS10195 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HHJ40_RS10200 ENOG4108N5C SNARE associated Golgi protein-related protein HHJ40_RS10205 ENOG4108KCW iron-sulfur cluster binding HHJ40_RS10210 ENOG4108RSN SNARE associated Golgi HHJ40_RS10215 ENOG4105CGK Exodeoxyribonuclease III HHJ40_RS10245 ENOG4108SPG Periplasmic Protein HHJ40_RS10255 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HHJ40_RS10265 ENOG4105KKI DNA-binding transcriptional activator OsmE HHJ40_RS10270 ENOG4105VZJ PTS System HHJ40_RS10275 ENOG4105CK1 PTS System HHJ40_RS10280 ENOG4105VCP PTS System HHJ40_RS10285 ENOG4105EZV Transcriptional regulator HHJ40_RS10290 ENOG4105F8D glycoside hydrolase family 4 HHJ40_RS10305 ENOG4105CH6 catalase HHJ40_RS10325 ENOG4108ETY sodium dicarboxylate symporter HHJ40_RS10330 ENOG4107K5X Membrane-bound metal-dependent hydrolase HHJ40_RS10335 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HHJ40_RS10340 ENOG4107PN8 YfeABCD locus regulator HHJ40_RS10350 ENOG4105P10 Uncharacterized protein ydiZ HHJ40_RS10355 ENOG4105DE4 1-phosphofructokinase HHJ40_RS10360 ENOG4108NE3 Salt-induced outer membrane protein HHJ40_RS10380 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HHJ40_RS10385 ENOG41082NX 50s ribosomal protein l35 HHJ40_RS10420 ENOG4108V06 Glutathione peroxidase HHJ40_RS10430 ENOG4108QBX (LipO)protein HHJ40_RS10435 ENOG4108TC0 Diguanylate phosphodiesterase HHJ40_RS10450 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ40_RS10460 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HHJ40_RS10465 ENOG4105CEY Amp-dependent synthetase and ligase HHJ40_RS10470 ENOG41090P5 ferredoxin-like protein HHJ40_RS10475 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ40_RS10480 ENOG4105C10 Electron transfer flavoprotein HHJ40_RS10485 ENOG4105CV7 Electron transfer flavoprotein HHJ40_RS10490 ENOG4105W4W Transcriptional regulator HHJ40_RS10495 ENOG4105C1G acyl-Coa dehydrogenase HHJ40_RS10500 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ40_RS10515 ENOG4105EMV Major Facilitator HHJ40_RS10520 ENOG4105EMV Major Facilitator HHJ40_RS10525 ENOG4105SUA Ydil protein HHJ40_RS10535 ENOG4105IPI Membrane HHJ40_RS10540 ENOG4105CQB FAD linked oxidase domain protein HHJ40_RS10545 ENOG4105KA0 thioesterase Superfamily protein HHJ40_RS10550 ENOG410671Z uncharacterized protein ydiH HHJ40_RS10555 ENOG4108Z4V iron-sulfur cluster assembly HHJ40_RS10560 ENOG4105DIW FeS assembly protein SUFB HHJ40_RS10565 ENOG4105C3K feS assembly ATPase SufC HHJ40_RS10570 ENOG4105JRK feS assembly protein SufD HHJ40_RS10585 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ40_RS10590 ENOG4105KMX major outer membrane lipoprotein HHJ40_RS10595 ENOG4105CA9 Pyruvate kinase HHJ40_RS10600 ENOG4105RFR Protein of unknown function (DUF2767) HHJ40_RS10605 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein HHJ40_RS10610 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HHJ40_RS10615 ENOG4105JVW HHJ40_RS10620 ENOG4108393 oxidoreductase Fe-S subunit HHJ40_RS10625 ENOG4108NWD Cytochrome HHJ40_RS10630 ENOG4108Y7C Conserved Protein HHJ40_RS10635 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HHJ40_RS10640 ENOG4105N0V mono-oxygenase ydhR HHJ40_RS10665 ENOG4108R6K riboflavin synthase, subunit alpha HHJ40_RS10670 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HHJ40_RS10675 ENOG4105CZQ inner membrane transport protein YdhC HHJ40_RS10680 ENOG4105F52 Transcriptional regulator HHJ40_RS10695 ENOG4105F27 Major Facilitator HHJ40_RS10700 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ40_RS10705 ENOG4105K4H Nlp p60 protein HHJ40_RS10710 ENOG4105M2J Glutaredoxin HHJ40_RS10715 ENOG4107QRT dEAD DEAH box helicase HHJ40_RS10725 ENOG4108UYE Lactoylglutathione lyase HHJ40_RS10730 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ40_RS10735 ENOG4108WUH Transcriptional regulator, TetR family HHJ40_RS10740 ENOG4105XZD Fe-S protein HHJ40_RS10745 ENOG4107RGM aldo keto reductase HHJ40_RS10750 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ40_RS10755 ENOG4105DSW Fusaric acid resistance protein HHJ40_RS10760 ENOG4105Y49 secretion protein, HlyD family HHJ40_RS10775 ENOG4108XTF Outer Membrane Lipoprotein HHJ40_RS10785 ENOG410642K Lysozyme inhibitor HHJ40_RS10800 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HHJ40_RS10805 ENOG4108K3A Glutathione S-transferase HHJ40_RS10810 ENOG4105DUX Transporter HHJ40_RS10815 ENOG4105CSM endonuclease III HHJ40_RS10825 ENOG4108UQQ Electron transport complex HHJ40_RS10850 ENOG4105M9B inner membrane protein ydgK HHJ40_RS10855 ENOG4105QZ5 OriC-binding nucleoid-associated protein HHJ40_RS10860 ENOG4106C6R beta-lactam resistance protein HHJ40_RS10865 ENOG4105D9R oxidoreductase HHJ40_RS10875 ENOG4105C87 Aminotransferase class I and II HHJ40_RS10880 ENOG4105CI1 PTS System HHJ40_RS10885 ENOG4107P2S Transcriptional regulator HHJ40_RS10890 ENOG4107ZQV short-chain dehydrogenase reductase HHJ40_RS10895 ENOG4105XEA Tetr family transcriptional regulator HHJ40_RS10900 ENOG4105CNT hydrolase family 2 HHJ40_RS10905 ENOG4105CT4 transporter HHJ40_RS10910 ENOG4108QNI outer membrane porin protein HHJ40_RS10915 ENOG4106J39 exported protein HHJ40_RS10920 ENOG4105EIP mannose-6-phosphate isomerase HHJ40_RS10925 ENOG4107GFK fumarate HHJ40_RS10930 ENOG4105C9Q fumarate hydratase class II HHJ40_RS10940 ENOG4105JJR Histidine kinase HHJ40_RS10945 ENOG4107EXC regulatoR HHJ40_RS10950 ENOG4105RA2 Membrane HHJ40_RS10960 ENOG4105D5Q Arginine ornithine antiporter HHJ40_RS10965 ENOG4105C5D exported protein HHJ40_RS10970 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ40_RS10975 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ40_RS10980 ENOG4105DSF transport protein HHJ40_RS10995 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HHJ40_RS11010 ENOG4105D94 Major Facilitator Superfamily HHJ40_RS11015 ENOG4106NZI LysR family Transcriptional regulator HHJ40_RS11020 ENOG4105DAG ROK family HHJ40_RS11025 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ40_RS11035 ENOG4108NEM leader-binding protein dmsD HHJ40_RS11040 ENOG4107KGK dmso reductase anchor subunit HHJ40_RS11045 ENOG4105QAX Iron-sulfur HHJ40_RS11050 ENOG4105C3J Cysteine desulfurase HHJ40_RS11055 ENOG4107QY8 reductase HHJ40_RS11060 ENOG4105KBG Protein of unknown function (DUF1161) HHJ40_RS11065 ENOG4105D69 UPF0257 lipoprotein ynfC HHJ40_RS11070 ENOG4108MK9 spermidine N(1)-acetyltransferase HHJ40_RS11085 ENOG4105CXK mandelate racemase muconate lactonizing HHJ40_RS11090 ENOG4105CPQ Dehydrogenase HHJ40_RS11100 ENOG4107R08 Integrase HHJ40_RS11115 ENOG4106G8A Qin prophage HHJ40_RS11135 ENOG41087BU transcriptional repressor DicA HHJ40_RS11170 ENOG4105WI6 cell killing protein encoded within cryptic prophage HHJ40_RS11185 ENOG4108MXB Protein of unknown function (DUF968) HHJ40_RS11190 ENOG4105HGD Antitermination protein HHJ40_RS11205 ENOG4105VEQ Cold shock protein HHJ40_RS11210 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HHJ40_RS11225 ENOG4108YV9 Protein of unknown function (DUF2514) HHJ40_RS11230 ENOG4105VEQ Cold shock protein HHJ40_RS11245 ENOG4106IAW HHJ40_RS11285 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) HHJ40_RS11360 ENOG4108X9F tail fiber protein HHJ40_RS11365 ENOG4105UZW Tail fiber assembly protein HHJ40_RS11370 ENOG4105MN3 Resolvase HHJ40_RS11375 ENOG4105W3V DNA-binding, transcriptional regulator HHJ40_RS11390 ENOG4105DEI Mannitol dehydrogenase HHJ40_RS11395 ENOG41061EV selenium-binding protein YdfZ HHJ40_RS11400 ENOG4107XBN GntR Family Transcriptional Regulator HHJ40_RS11405 ENOG4105EMU Dehydrogenase HHJ40_RS11410 ENOG4105DGW oligopeptidase A HHJ40_RS11415 ENOG4108WTK competence damage-inducible protein HHJ40_RS11420 ENOG4108YDI single-species biofilm formation on inanimate substrate HHJ40_RS11425 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria HHJ40_RS11435 ENOG4105E5W Transporter HHJ40_RS11440 ENOG4108594 Permease of the drug metabolite transporter HHJ40_RS11445 ENOG4105FDP GntR family transcriptional regulator HHJ40_RS11455 ENOG4105CK1 PTS System HHJ40_RS11460 ENOG4105VCP PTS System HHJ40_RS11470 ENOG4105CS2 ec 3.2.1.21 HHJ40_RS11475 ENOG4106DNR multiple antibiotic resistance protein HHJ40_RS11480 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HHJ40_RS11485 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HHJ40_RS11505 ENOG4105EGI Transcriptional regulator HHJ40_RS11510 ENOG4105C26 Dehydrogenase HHJ40_RS11515 ENOG4105CSV Glutaminase HHJ40_RS11520 ENOG4105M0C cytoplasmic protein HHJ40_RS11525 ENOG4105BZU Histidine kinase HHJ40_RS11535 ENOG4105FFC UPF0187 protein HHJ40_RS11545 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound HHJ40_RS11570 ENOG4105C2J ABC transporter HHJ40_RS11590 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein HHJ40_RS11595 ENOG4105CAF HipA N-terminal domain protein HHJ40_RS11605 ENOG4108RQP Major type 1 subunit fimbrin HHJ40_RS11615 ENOG4105CW0 outer membrane usher protein HHJ40_RS11620 ENOG4108WDE Fimbrial protein HHJ40_RS11625 ENOG4106318 fimbrial-like protein YdeR HHJ40_RS11630 ENOG4106PIH fimbrial-like protein ydeQ HHJ40_RS11635 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HHJ40_RS11645 ENOG4105Z68 AraC Family Transcriptional Regulator HHJ40_RS11650 ENOG4105ENH Sulfatase HHJ40_RS11655 ENOG4105C4X radical SAM domain protein HHJ40_RS11665 ENOG4105CQ0 ABC transporter HHJ40_RS11670 ENOG4105PE1 Receptor HHJ40_RS11675 ENOG4107RAN Peptidase, M16 HHJ40_RS11685 ENOG4105E5D amino acid HHJ40_RS11690 ENOG4105F32 YngK protein HHJ40_RS11700 ENOG4105BZU Histidine kinase HHJ40_RS11705 ENOG4108UQS dipeptidase HHJ40_RS11710 ENOG4105DEF Extracellular solute-binding protein, family 5 HHJ40_RS11715 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ40_RS11720 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ40_RS11725 ENOG4105C3U ABC transporter HHJ40_RS11730 ENOG4107H6U ABC transporter HHJ40_RS11735 ENOG4108Z9K Osmotically inducible protein HHJ40_RS11740 ENOG4105TPS biofilm-dependent modulation protein HHJ40_RS11745 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HHJ40_RS11755 ENOG4105DQ4 alcohol dehydrogenase HHJ40_RS11760 ENOG41084S7 Plasmid maintenance system antidote protein HHJ40_RS11765 ENOG4108MG3 formate dehydrogenase HHJ40_RS11770 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ40_RS11780 ENOG4105RPH Inner membrane protein YddG HHJ40_RS11790 ENOG4108UI3 Leucine Rich repeat HHJ40_RS11795 ENOG4107QND Nitrite extrusion protein HHJ40_RS11800 ENOG4105CRU nitrate reductase, alpha subunit HHJ40_RS11805 ENOG4108IUE nitrate reductase beta subunit HHJ40_RS11810 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HHJ40_RS11815 ENOG4105D0D Nitrate reductase 2, gamma subunit HHJ40_RS11820 ENOG4105JAB phenazine biosynthesis protein, phzf family HHJ40_RS11825 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HHJ40_RS11830 ENOG4108MEJ flavin reductase domain protein HHJ40_RS11865 ENOG4108N27 Glutathione S-transferase HHJ40_RS11870 ENOG4105C85 amino acid HHJ40_RS11875 ENOG4108NS2 receptor HHJ40_RS11880 ENOG4105CHB tonB-dependent Receptor HHJ40_RS11885 ENOG4108WYP Transcriptional regulator HHJ40_RS11890 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein HHJ40_RS11895 ENOG4108Z7F N-acetyltransferase HHJ40_RS11900 ENOG4108T9Y Inner membrane protein ydcZ HHJ40_RS11905 ENOG4105R71 cytoplasmic protein HHJ40_RS11910 ENOG410654E Membrane HHJ40_RS11930 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HHJ40_RS11935 ENOG4105D81 ABC transporter, permease HHJ40_RS11940 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ40_RS11945 ENOG4107TYH extracellular solute-binding protein family 1 HHJ40_RS11950 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HHJ40_RS11955 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin HHJ40_RS11965 ENOG4105RR0 Protein of unknown function (DUF2554) HHJ40_RS11970 ENOG4105CFP Peptidase U32 HHJ40_RS11975 ENOG4108JCI Transcriptional regulator HHJ40_RS11980 ENOG4105DKK Benzoate HHJ40_RS11985 ENOG4105D7V transposase HHJ40_RS11995 ENOG4108KKZ (LipO)protein HHJ40_RS12000 ENOG41088CC tellurite resistance protein tehB HHJ40_RS12005 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HHJ40_RS12010 ENOG4107WE3 acetyltransferase YdcK HHJ40_RS12015 ENOG4108Z9I -acetyltransferase HHJ40_RS12020 ENOG4105Z2P Protein of unknown function (DUF465) HHJ40_RS12030 ENOG4105E32 cytoplasmic protein HHJ40_RS12035 ENOG4105DDW LysR family Transcriptional regulator HHJ40_RS12040 ENOG4105C8Q Methyl-accepting chemotaxis HHJ40_RS12045 ENOG4107NK6 Hok/gef family HHJ40_RS12050 ENOG4105UPP uncharacterized protein ydcA HHJ40_RS12055 ENOG4105CPW cytochrome b561 HHJ40_RS12060 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ40_RS12065 ENOG4105C26 Dehydrogenase HHJ40_RS12070 ENOG4107DB1 DUF218 domain HHJ40_RS12075 ENOG4105CQ7 ATP-dependent helicase HHJ40_RS12085 ENOG41077RS Phosphatase HHJ40_RS12090 ENOG4105E8V Alpha Beta Hydrolase Fold protein HHJ40_RS12095 ENOG4108HPI phosphatidate Cytidylyltransferase HHJ40_RS12100 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase HHJ40_RS12110 ENOG4107S5I aldo keto reductase HHJ40_RS12115 ENOG4108Z0R Transferase HHJ40_RS12120 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein HHJ40_RS12125 ENOG4105DZS Phenylacetate-CoA ligase HHJ40_RS12130 ENOG4105CHU acetyl-coa acetyltransferase HHJ40_RS12135 ENOG4108ZJI phenylacetic acid degradation protein HHJ40_RS12140 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HHJ40_RS12145 ENOG4108UKI Enoyl-CoA hydratase HHJ40_RS12150 ENOG4105E39 Enoyl-CoA hydratase HHJ40_RS12155 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ40_RS12160 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit HHJ40_RS12165 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit HHJ40_RS12170 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit HHJ40_RS12175 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit HHJ40_RS12180 ENOG4105DXM phenylacetic acid degradation protein HHJ40_RS12185 ENOG4105F11 amine oxidase HHJ40_RS12190 ENOG4105C26 Dehydrogenase HHJ40_RS12195 ENOG4108WFR AraC Family Transcriptional Regulator HHJ40_RS12200 ENOG4105WXT Conserved Protein HHJ40_RS12205 ENOG410689M (LipO)protein HHJ40_RS12210 ENOG4107H52 Dicarboxylate transport HHJ40_RS12215 ENOG4105C5I Dehydrogenase HHJ40_RS12220 ENOG41090X5 Heat shock protein hslJ HHJ40_RS12225 ENOG4105IKK cytoplasmic protein HHJ40_RS12230 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HHJ40_RS12235 ENOG4105FCK Membrane HHJ40_RS12240 ENOG4108RW8 Universal stress protein F HHJ40_RS12250 ENOG4105C1J atp-dependent rna helicase HHJ40_RS12260 ENOG4105BZU Histidine kinase HHJ40_RS12265 ENOG4108DG9 Smr protein MutS2 HHJ40_RS12270 ENOG4106KR7 LysR family Transcriptional regulator HHJ40_RS12275 ENOG4105CH2 amidohydrolase HHJ40_RS12280 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B HHJ40_RS12285 ENOG4105CFC Transporter HHJ40_RS12290 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ40_RS12295 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HHJ40_RS12300 ENOG4105Q9Y Universal stress protein HHJ40_RS12305 ENOG4105S5I Membrane HHJ40_RS12310 ENOG4105D64 Mechanosensitive ion channel HHJ40_RS12315 ENOG4107QSI ABC, transporter HHJ40_RS12320 ENOG4105EQ2 LysR family Transcriptional regulator HHJ40_RS12325 ENOG4105ENX hydrolase HHJ40_RS12330 ENOG4105ENX hydrolase HHJ40_RS12340 ENOG4105KXI murein peptide amidase A HHJ40_RS12345 ENOG4107S8C mandelate racemase muconate lactonizing HHJ40_RS12350 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HHJ40_RS12355 ENOG4108JU8 Transcriptional regulator HHJ40_RS12365 ENOG4105CM6 amino acid regulated cytosolic protein HHJ40_RS12370 ENOG4105FKQ transcriptional regulator HHJ40_RS12375 ENOG4107EFV Outer membrane protein G HHJ40_RS12380 ENOG4108IJ9 (ABC) transporter HHJ40_RS12385 ENOG4107URF beta-phospho-glucomutase HHJ40_RS12390 ENOG4105C71 hydrolase family 65, central catalytic HHJ40_RS12395 ENOG4105CK5 oxidoreductase HHJ40_RS12400 ENOG4107TYA transient receptor potential locus HHJ40_RS12405 ENOG4107RRD Dehydrogenase HHJ40_RS12410 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component HHJ40_RS12415 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component HHJ40_RS12420 ENOG4105WEM extracellular solute-binding protein HHJ40_RS12425 ENOG4107QW3 Sucrose phosphorylase HHJ40_RS12430 ENOG4105K8Z Phage shock protein HHJ40_RS12435 ENOG4105NNG Peripheral inner membrane phage-shock protein HHJ40_RS12440 ENOG4105FM1 phage shock protein C HHJ40_RS12445 ENOG4105YYT phage shock protein B HHJ40_RS12450 ENOG41087YS Phage shock protein A HHJ40_RS12455 ENOG4105E51 psp operon transcriptional activator HHJ40_RS12460 ENOG4108JPW Aminotransferase HHJ40_RS12465 ENOG4105CJP fad dependent oxidoreductase HHJ40_RS12470 ENOG4105C26 Dehydrogenase HHJ40_RS12475 ENOG4107VRI Transcriptional regulator HHJ40_RS12480 ENOG4108Z86 Glutamine amidotransferase HHJ40_RS12485 ENOG4105CFQ glutamine synthetase HHJ40_RS12495 ENOG4105CUB amino acid HHJ40_RS12500 ENOG4105N0E Protein of unknown function (DUF2543) HHJ40_RS12505 ENOG4108HIY periplasmic HHJ40_RS12510 ENOG4108I5W peptide transport system, permease protein HHJ40_RS12515 ENOG4108EU3 peptide transport system, permease HHJ40_RS12520 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HHJ40_RS12525 ENOG4108JQ2 peptide transport system atp-binding protein HHJ40_RS12530 ENOG4105WDY DNA (cytosine-5-)-methyltransferase HHJ40_RS12535 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HHJ40_RS12540 ENOG4105Q4T oxidoreductase HHJ40_RS12555 ENOG4105BZU Histidine kinase HHJ40_RS12560 ENOG410643D UPF0509 protein HHJ40_RS12565 ENOG4105N2W Transcriptional regulator HHJ40_RS12575 ENOG4108ZJT translation initiation factor, Sui1 HHJ40_RS12585 ENOG4105CFV Tetratricopeptide repeat protein HHJ40_RS12590 ENOG4105Q4A inner membrane protein yciS HHJ40_RS12595 ENOG4105EYK Phosphatidylglycerophosphatase B HHJ40_RS12625 ENOG4107R11 Transcriptional regulator HHJ40_RS12630 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ40_RS12635 ENOG4105RKX Protein of unknown function (DUF2498) HHJ40_RS12640 ENOG4105ERU peptidase HHJ40_RS12645 ENOG4105UBK short-chain dehydrogenase reductase HHJ40_RS12650 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HHJ40_RS12655 ENOG4105FE9 pseudouridine synthase HHJ40_RS12660 ENOG4107RTD sua5 ycio yrdc ywlc family protein HHJ40_RS12665 ENOG4105DB7 PHP domain protein HHJ40_RS12675 ENOG4105CRQ synthase (Component I) HHJ40_RS12680 ENOG4108EFP Anthranilate synthase component II HHJ40_RS12685 ENOG4105DK0 Indole-3-glycerol phosphate synthase HHJ40_RS12705 ENOG4108Z9Z response to DNA damage stimulus HHJ40_RS12710 ENOG4108N8X transition metal ion binding HHJ40_RS12715 ENOG4105EIF outer membrane protein W HHJ40_RS12735 ENOG4105NAU thioesterase Superfamily protein HHJ40_RS12740 ENOG410822N TonB family HHJ40_RS12745 ENOG4105K9H YciI-like protein HHJ40_RS12750 ENOG4107SVH Potassium channel protein HHJ40_RS12770 ENOG4108JQ7 (ABC) transporter HHJ40_RS12775 ENOG4105C3U ABC transporter HHJ40_RS12780 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ40_RS12785 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ40_RS12790 ENOG4108J59 Extracellular solute-binding protein, family 5 HHJ40_RS12800 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HHJ40_RS12805 ENOG4105C0A alcohol dehydrogenase HHJ40_RS12815 ENOG4107104 thymidine kinase HHJ40_RS12820 ENOG4108SAU DNA-binding protein H-ns HHJ40_RS12825 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ40_RS12830 ENOG4105I93 response regulator HHJ40_RS12835 ENOG4105D78 K07001 NTE family protein HHJ40_RS12840 ENOG4105K5B UPF0225 protein HHJ40_RS12845 ENOG4105CIY formyltetrahydrofolate deformylase HHJ40_RS12870 ENOG41076YT nitrate reductase, gamma subunit HHJ40_RS12875 ENOG4105R3A Nitrate reductase HHJ40_RS12880 ENOG4108IUE nitrate reductase beta subunit HHJ40_RS12885 ENOG4105CRU nitrate reductase, alpha subunit HHJ40_RS12890 ENOG4105DQQ Major facilitator superfamily MFS_1 HHJ40_RS12895 ENOG4105BZU Histidine kinase HHJ40_RS12900 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ40_RS12905 ENOG4105ID0 Putative invasin HHJ40_RS12910 ENOG41090EX DsrE family HHJ40_RS12915 ENOG4108NH8 Cation transport protein HHJ40_RS12920 ENOG4105WS7 Cation transport regulator HHJ40_RS12925 ENOG4105EWV Sodium calcium exchanger membrane region HHJ40_RS12945 ENOG41063JG Transcriptional regulator HHJ40_RS12950 ENOG4108YY7 Invasion gene expression up-regulator SirB HHJ40_RS12955 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HHJ40_RS12980 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HHJ40_RS12985 ENOG4105CHH sulfate transporter HHJ40_RS12990 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HHJ40_RS13000 ENOG4105C3G gtp-binding protein HHJ40_RS13005 ENOG4105I1J Autotransporter HHJ40_RS13010 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HHJ40_RS13015 ENOG4105CMT Dihydroxyacetone kinase HHJ40_RS13020 ENOG4108UTZ Dihydroxyacetone kinase HHJ40_RS13025 ENOG4105VDH Dihydroxyacetone kinase HHJ40_RS13045 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HHJ40_RS13050 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division HHJ40_RS13055 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HHJ40_RS13065 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ40_RS13075 ENOG4105ED1 spovr family HHJ40_RS13095 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HHJ40_RS13100 ENOG4105KT5 UmuD protein HHJ40_RS13115 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HHJ40_RS13125 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HHJ40_RS13130 ENOG4105S66 prophage protein HHJ40_RS13140 ENOG4107QMS site-determining protein HHJ40_RS13175 ENOG410658X HHJ40_RS13195 ENOG4105BZU Histidine kinase HHJ40_RS13200 ENOG410738I uncharacterized protein ymgC HHJ40_RS13210 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB HHJ40_RS13215 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component HHJ40_RS13220 ENOG4105BZU Histidine kinase HHJ40_RS13225 ENOG4108XDN Transcriptional regulator HHJ40_RS13230 ENOG41064WM Uncharacterized protein YcgX HHJ40_RS13245 ENOG4108HMX isocitrate dehydrogenase (NADP) HHJ40_RS13255 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 HHJ40_RS13265 ENOG4105UZW Tail fiber assembly protein HHJ40_RS13270 ENOG4108X9F tail fiber protein HHJ40_RS13345 ENOG4105IM0 capsid protein HHJ40_RS13355 ENOG4105F7J membrane-bound serine protease HHJ40_RS13365 ENOG4107DE1 head-to-tail joining protein HHJ40_RS13370 ENOG4105UZW Tail fiber assembly protein HHJ40_RS13375 ENOG4105FKG DNA packaging protein HHJ40_RS13380 ENOG4105QYK bacteriophage lambda Bor protein homolog HHJ40_RS13390 ENOG4105KUS lysozyme HHJ40_RS13395 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HHJ40_RS13405 ENOG4105HRS Antitermination protein HHJ40_RS13415 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HHJ40_RS13420 ENOG4105RWQ Protein of unknown function (DUF1364) HHJ40_RS13425 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 HHJ40_RS13430 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi HHJ40_RS13450 ENOG4107TII Recombinase HHJ40_RS13460 ENOG410814C multidrug resistance protein HHJ40_RS13550 ENOG4108I1J Integrase HHJ40_RS13555 ENOG4108HMX isocitrate dehydrogenase (NADP) HHJ40_RS13560 ENOG4108R99 pseudouridine synthase HHJ40_RS13580 ENOG4107QTF adenylosuccinate lyase HHJ40_RS13585 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ40_RS13590 ENOG4105IFJ Histidine kinase HHJ40_RS13595 ENOG4105EZE Cupin 4 family protein HHJ40_RS13605 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ40_RS13615 ENOG4105D38 putrescine abc transporter HHJ40_RS13620 ENOG4107RUE extracellular solute-binding protein family 1 HHJ40_RS13635 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HHJ40_RS13645 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ40_RS13650 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HHJ40_RS13655 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ40_RS13660 ENOG4105IQC Inner membrane protein YcfT HHJ40_RS13665 ENOG4108JA2 transcriptioN-repair coupling factor HHJ40_RS13670 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ40_RS13675 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HHJ40_RS13680 ENOG4108IND Tetr family transcriptional regulator HHJ40_RS13685 ENOG4107MBR 17 kDa surface antigen HHJ40_RS13690 ENOG4105CEP NADH dehydrogenase HHJ40_RS13710 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HHJ40_RS13715 ENOG41090DQ Lipoprotein HHJ40_RS13720 ENOG4105K59 histidine triad (HIT) protein HHJ40_RS13725 ENOG4105CNM Receptor HHJ40_RS13730 ENOG4105CI1 PTS System HHJ40_RS13735 ENOG4105F8V Hydrolase, tatD family HHJ40_RS13740 ENOG4107QRG dna polymerase iii HHJ40_RS13750 ENOG4105HHA aminodeoxychorismate lyase HHJ40_RS13755 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HHJ40_RS13760 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ40_RS13765 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ40_RS13770 ENOG4105CHR reductase HHJ40_RS13775 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HHJ40_RS13795 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HHJ40_RS13800 ENOG4108UHJ MAF-like protein HHJ40_RS13805 ENOG4105EI2 Pseudouridine synthase HHJ40_RS13810 ENOG4107QQB Ribonuclease E HHJ40_RS13815 ENOG4105DTJ flagellar hook-associated protein HHJ40_RS13820 ENOG4105E1Q flagellar hook-associated protein HHJ40_RS13825 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HHJ40_RS13840 ENOG4105CGA flagellar basal-body rod protein FlgG HHJ40_RS13845 ENOG4108KPB Flagellar basal-body rod protein FlgF HHJ40_RS13850 ENOG4105BZE flagellar hook protein, FlgE HHJ40_RS13855 ENOG4105W00 Flagellar hook capping protein HHJ40_RS13860 ENOG4108ZC9 flagellar basal-body rod protein flgc HHJ40_RS13865 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HHJ40_RS13870 ENOG4105CKS Flagella basal body P-ring formation protein flgA HHJ40_RS13875 ENOG4105M9M anti-sigma28 factor FlgM HHJ40_RS13880 ENOG4105QVD Flagella synthesis protein FlgN HHJ40_RS13885 ENOG4105CJR Integral membrane protein (MviN HHJ40_RS13890 ENOG4105EP9 oxidoreductase HHJ40_RS13900 ENOG4105D9U N-acetyltransferase HHJ40_RS13910 ENOG4105E9S glutaredoxin 2 HHJ40_RS13915 ENOG4105F3T (LipO)protein HHJ40_RS13925 ENOG4105MEA DNA damage-inducible protein i HHJ40_RS13930 ENOG4105PVA Biofilm formation regulatory protein BssS HHJ40_RS13940 ENOG4106974 biofilm formation HHJ40_RS13945 ENOG4105DS1 cytochrome b561 HHJ40_RS13950 ENOG4108YYC ycei family HHJ40_RS13960 ENOG4105D1S lipid A biosynthesis HHJ40_RS13970 ENOG4108W47 Acidic protein msyB HHJ40_RS13975 ENOG4105NAC (LipO)protein HHJ40_RS13980 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HHJ40_RS13995 ENOG4107RZC phospholipase d HHJ40_RS14000 ENOG4108UVJ appr-1-p processing domain protein HHJ40_RS14015 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HHJ40_RS14020 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HHJ40_RS14025 ENOG41086KC Transcriptional regulator HHJ40_RS14030 ENOG4108XDW curli assembly protein CsgE HHJ40_RS14035 ENOG4108WYR Curli production assembly transport component, CsgF HHJ40_RS14040 ENOG4105P8Q Curli production assembly transport component CsgG HHJ40_RS14045 ENOG4108UQ5 membrane protein YcdZ HHJ40_RS14050 ENOG4107XHZ cytoplasmic chaperone TorD family protein HHJ40_RS14060 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase HHJ40_RS14075 ENOG4108T85 Membrane HHJ40_RS14090 ENOG4105BZU Histidine kinase HHJ40_RS14095 ENOG4108TUY outer membrane protein PgaA HHJ40_RS14100 ENOG4107BJW polysaccharide deacetylase HHJ40_RS14105 ENOG4105CND Glycosyl transferase, family 2 HHJ40_RS14115 ENOG4105D5M phosphate starvation-inducible protein HHJ40_RS14125 ENOG410650H (LipO)protein HHJ40_RS14140 ENOG4105CK7 Sodium proline symporter HHJ40_RS14150 ENOG4105C26 Dehydrogenase HHJ40_RS14155 ENOG4108R86 Transcriptional regulator HHJ40_RS14190 ENOG4105C2W permease HHJ40_RS14195 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HHJ40_RS14205 ENOG4105XH3 HHJ40_RS14210 ENOG4105D6F Phosphatase HHJ40_RS14235 ENOG4108J2R molybdopterin oxidoreductase HHJ40_RS14240 ENOG4105CUW cytochrome C-TYPE protein HHJ40_RS14245 ENOG4106WF9 DNA-binding transcriptional regulator TorR HHJ40_RS14250 ENOG4108SV3 Tmao reductase system periplasmic protein tort HHJ40_RS14255 ENOG4105BZU Histidine kinase HHJ40_RS14260 ENOG4105HEE Binding Domain protein HHJ40_RS14265 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HHJ40_RS14280 ENOG4105VEQ Cold shock protein HHJ40_RS14285 ENOG41060EU Cold shock-like protein HHJ40_RS14295 ENOG4108Y9B (LipO)protein HHJ40_RS14300 ENOG4108W78 Pfam:DUF1017 HHJ40_RS14305 ENOG4105E3R (LipO)protein HHJ40_RS14310 ENOG4105DAY polysaccharide export protein HHJ40_RS14315 ENOG4107ZF2 Phosphatase HHJ40_RS14320 ENOG4105D75 Capsular exopolysaccharide family HHJ40_RS14325 ENOG4105D6F Phosphatase HHJ40_RS14335 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ40_RS14340 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ40_RS14345 ENOG4105MVP hydrogenase-1 operon protein HyaF HHJ40_RS14350 ENOG4108VXY Hydrogenase-1 operon protein HyaE HHJ40_RS14355 ENOG4108USZ hydrogenase HHJ40_RS14360 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HHJ40_RS14365 ENOG4105DPX Hydrogenase, large subunit HHJ40_RS14370 ENOG4105E3S small subunit HHJ40_RS14380 ENOG4108MN8 Membrane HHJ40_RS14385 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HHJ40_RS14390 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HHJ40_RS14405 ENOG4105K4P CoA-binding domain protein HHJ40_RS14420 ENOG41088T4 Helicase IV HHJ40_RS14425 ENOG410901E Membrane HHJ40_RS14430 ENOG4105EM2 membrane HHJ40_RS14435 ENOG4108RZ1 DNA transformation protein HHJ40_RS14445 ENOG4105UYK outer membrane protein a HHJ40_RS14455 ENOG4105DAN ATP-dependent protease HHJ40_RS14465 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HHJ40_RS14470 ENOG4108Q2G (LipO)protein HHJ40_RS14475 ENOG4105DY2 Paraquat-inducible protein b HHJ40_RS14480 ENOG4105F1S paraquat-inducible protein a HHJ40_RS14485 ENOG4105C5H ABC transporter HHJ40_RS14495 ENOG4105QVC MOSC domain-containing protein HHJ40_RS14500 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HHJ40_RS14510 ENOG4106PH7 chaperone HHJ40_RS14515 ENOG4105MX3 Fimbrial HHJ40_RS14520 ENOG4105Q7J Fimbrial HHJ40_RS14525 ENOG4108MDY Fimbrial HHJ40_RS14530 ENOG4105CW0 outer membrane usher protein HHJ40_RS14535 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae HHJ40_RS14540 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon HHJ40_RS14545 ENOG4108UZX fmn reductase HHJ40_RS14550 ENOG4105GVF (ABC) transporter HHJ40_RS14560 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HHJ40_RS14570 ENOG4105CD8 aminopeptidase N HHJ40_RS14585 ENOG4105FCK Membrane HHJ40_RS14590 ENOG4105CGF Aromatic amino acid aminotransferase HHJ40_RS14600 ENOG4105C5X domain protein HHJ40_RS14605 ENOG4105EAQ (twin-arginine translocation) pathway signal HHJ40_RS14610 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HHJ40_RS14615 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) HHJ40_RS14620 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HHJ40_RS14630 ENOG4106371 Methyltransferase HHJ40_RS14635 ENOG4107S90 membrAne HHJ40_RS14640 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HHJ40_RS14655 ENOG4105T0Z Conserved Protein HHJ40_RS14665 ENOG4105BZ1 (ABC) transporter HHJ40_RS14670 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HHJ40_RS14680 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HHJ40_RS14690 ENOG4108K0D peptidase, M48 HHJ40_RS14705 ENOG4107VMU Membrane HHJ40_RS14710 ENOG4105DDY UPF0142 protein ycaO HHJ40_RS14715 ENOG4105TMB Formate nitrite transporter HHJ40_RS14720 ENOG4105C6N Formate acetyltransferase HHJ40_RS14725 ENOG4105F1A Pyruvate formate-lyase HHJ40_RS14730 ENOG4108X0B nad(p)h dehydrogenase (quinone) HHJ40_RS14735 ENOG410642W LysR family Transcriptional regulator HHJ40_RS14740 ENOG4105E5D amino acid HHJ40_RS14750 ENOG4105CHJ isochorismatase hydrolase HHJ40_RS14755 ENOG4107KGK dmso reductase anchor subunit HHJ40_RS14760 ENOG4105QAX Iron-sulfur HHJ40_RS14765 ENOG4107QY8 reductase HHJ40_RS14775 ENOG4105D1H recombination factor protein RarA HHJ40_RS14785 ENOG4105CNU cell division protein FtsK HHJ40_RS14795 ENOG4105C3M thioredoxin reductase HHJ40_RS14800 ENOG4108JJ9 ABC, transporter HHJ40_RS14805 ENOG4108JJ8 (ABC) transporter HHJ40_RS14815 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HHJ40_RS14825 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ40_RS14835 ENOG4105VEQ Cold shock protein HHJ40_RS14840 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HHJ40_RS14845 ENOG4105DJY efflux transporter, rnd family, mfp subunit HHJ40_RS14850 ENOG4108MJ5 VirK protein HHJ40_RS14855 ENOG4105CPB ATP-dependent endonuclease of the OLD family HHJ40_RS14860 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ40_RS14865 ENOG4105DWU Membrane HHJ40_RS14875 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ40_RS14880 ENOG4105C7K acetolactate synthase HHJ40_RS14885 ENOG4105C5W Aldolase HHJ40_RS14890 ENOG4105CGD Nad-dependent epimerase dehydratase HHJ40_RS14895 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HHJ40_RS14900 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ40_RS14910 ENOG41064MM (LipO)protein HHJ40_RS14915 ENOG4105E5Z arginine transporter ATP-binding subunit HHJ40_RS14920 ENOG4106PMH Extracellular solute-binding protein family 3 HHJ40_RS14925 ENOG4105GBT ABC transporter HHJ40_RS14930 ENOG4105DMR ABC, transporter HHJ40_RS14935 ENOG4106TNF Periplasmic binding protein HHJ40_RS14945 ENOG4105RBQ inner membrane protein ybjO HHJ40_RS14950 ENOG4105D38 putrescine abc transporter HHJ40_RS14955 ENOG4105F38 ABC transporter, permease HHJ40_RS14960 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ40_RS14965 ENOG4107RUE extracellular solute-binding protein family 1 HHJ40_RS14970 ENOG4108RMJ sensory transduction regulator HHJ40_RS14980 ENOG4108DBC nitroreductase HHJ40_RS14985 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HHJ40_RS14990 ENOG41090BQ Glutaredoxin HHJ40_RS14995 ENOG4105GWF inner membrane protein YbjM HHJ40_RS15005 ENOG4108RFG Tetr family transcriptional regulator HHJ40_RS15010 ENOG4106UW1 Major Facilitator superfamily HHJ40_RS15015 ENOG4108HCJ Hydrolase HHJ40_RS15025 ENOG4107QF7 multi-drug HHJ40_RS15030 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HHJ40_RS15035 ENOG4107FB0 transcriptional regulator DeoR family HHJ40_RS15040 ENOG4105DZ1 carboxypeptidase HHJ40_RS15045 ENOG4108TGY Glutathione S-transferase HHJ40_RS15050 ENOG4105D8V Glucose sorbosone dehydrogenase HHJ40_RS15055 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HHJ40_RS15065 ENOG41064RH membrane protein YliF HHJ40_RS15070 ENOG4105BZU Histidine kinase HHJ40_RS15095 ENOG4105D44 asparaginase HHJ40_RS15100 ENOG4105CVM Molybdenum cofactor synthesis domain protein HHJ40_RS15105 ENOG4105D06 uba thif-type nad fad binding protein HHJ40_RS15110 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ40_RS15115 ENOG4105F1A Pyruvate formate-lyase HHJ40_RS15125 ENOG4108HCJ Hydrolase HHJ40_RS15130 ENOG41072TH Protein of unknown function (DUF1479) HHJ40_RS15140 ENOG4105C5H ABC transporter HHJ40_RS15145 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ40_RS15150 ENOG4105F4P )-transporter HHJ40_RS15155 ENOG4105KST dependent repressor HHJ40_RS15165 ENOG4108I6E Sulfatase HHJ40_RS15170 ENOG4108T1M outer membrane protein x HHJ40_RS15180 ENOG4107AQZ Membrane HHJ40_RS15190 ENOG4107R0W ABC transporter HHJ40_RS15195 ENOG4105E5Q amino acid AbC transporter HHJ40_RS15200 ENOG4105CDA abc transporter atp-binding protein HHJ40_RS15205 ENOG4105D8X mechanosensitive ion channel HHJ40_RS15215 ENOG4105ZY9 UPF0379 protein ybiM HHJ40_RS15220 ENOG4108IU3 tonb-dependent siderophore receptor HHJ40_RS15230 ENOG4105KSC Transcriptional regulator, TraR DksA family HHJ40_RS15235 ENOG4105VR4 UPF0379 protein ybiJ HHJ40_RS15240 ENOG4105DG4 malate L-lactate dehydrogenase HHJ40_RS15245 ENOG4108MTB glycosyl transferase family HHJ40_RS15250 ENOG4105DVT helicase HHJ40_RS15255 ENOG4108UV1 cellular component movement HHJ40_RS15260 ENOG4105C1J atp-dependent rna helicase HHJ40_RS15265 ENOG4107MVR Transcriptional regulator HHJ40_RS15275 ENOG4105CJ1 ABC, transporter HHJ40_RS15280 ENOG4107QWP ABC-2 type transporter HHJ40_RS15285 ENOG4107QWP ABC-2 type transporter HHJ40_RS15290 ENOG4105I9U inner membrane protein ybhQ HHJ40_RS15295 ENOG4105X23 Endonuclease Exonuclease phosphatase HHJ40_RS15300 ENOG4105DZQ phospholipase D Transphosphatidylase HHJ40_RS15305 ENOG4107UXM Membrane HHJ40_RS15310 ENOG410733J conserved inner membrane protein HHJ40_RS15320 ENOG4105HFZ Membrane HHJ40_RS15325 ENOG4108ZAF Molybdopterin HHJ40_RS15330 ENOG4105M00 molybdopterin converting factor, subunit 1 HHJ40_RS15340 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ40_RS15350 ENOG4105CHW UPF0052 protein HHJ40_RS15360 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ40_RS15365 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HHJ40_RS15380 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HHJ40_RS15385 ENOG4108V1U phospholipid-binding protein HHJ40_RS15390 ENOG4105NBR Pectinesterase HHJ40_RS15395 ENOG4107QM5 aconitate hydratase HHJ40_RS15400 ENOG4107QPK )-transporter HHJ40_RS15405 ENOG4105C7F AcnD-accessory protein PrpF HHJ40_RS15410 ENOG4105F04 LysR family Transcriptional regulator HHJ40_RS15420 ENOG4108K4B hydrolase HHJ40_RS15430 ENOG4105E0C molybdate abc transporter HHJ40_RS15435 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HHJ40_RS15445 ENOG4105F4R Transcriptional regulator mode HHJ40_RS15450 ENOG4105DKW ABC transporter HHJ40_RS15455 ENOG4105CMR udp-glucose 4-epimerase HHJ40_RS15460 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HHJ40_RS15470 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HHJ40_RS15480 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ40_RS15485 ENOG4105JND homeobox protein HHJ40_RS15490 ENOG4105PGM cation diffusion facilitator family transporter HHJ40_RS15495 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HHJ40_RS15545 ENOG4105UFD tol-pal system protein YbgF HHJ40_RS15550 ENOG4105KCK Peptidoglycan-associated lipoprotein HHJ40_RS15560 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HHJ40_RS15570 ENOG4105E02 MotA TolQ exbB proton channel HHJ40_RS15575 ENOG4107YD3 Thioesterase HHJ40_RS15580 ENOG4105KJB cyd operon protein YbgE HHJ40_RS15590 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ40_RS15595 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ40_RS15600 ENOG4105C8I hydrolase, family 38 HHJ40_RS15605 ENOG4105DM4 PTS System HHJ40_RS15610 ENOG4105FDP GntR family transcriptional regulator HHJ40_RS15615 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HHJ40_RS15625 ENOG4105C7S Dehydrogenase HHJ40_RS15630 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HHJ40_RS15635 ENOG4105E33 succinate dehydrogenase HHJ40_RS15640 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ40_RS15645 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HHJ40_RS15650 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HHJ40_RS15660 ENOG4105BZN citrate synthase HHJ40_RS15665 ENOG4106UBK fimbrial-like adhesin protein HHJ40_RS15670 ENOG4106PG1 outer membrane usher protein HHJ40_RS15675 ENOG4108TTM chaperone HHJ40_RS15680 ENOG4108MY7 Fimbrial HHJ40_RS15685 ENOG4108KK1 membrane protein AbrB duplication HHJ40_RS15700 ENOG4107R7A Allophanate hydrolase subunit 2 HHJ40_RS15705 ENOG4105P4J Allophanate hydrolase, subunit 1 HHJ40_RS15710 ENOG4107QNR UPF0135 protein HHJ40_RS15715 ENOG4105DUX Transporter HHJ40_RS15720 ENOG4105CVP deoxyribo-dipyrimidine photolyase HHJ40_RS15725 ENOG4107SEY Conserved Protein HHJ40_RS15760 ENOG41079JQ Membrane HHJ40_RS15795 ENOG4105XIQ Protein of unknown function (DUF2517) HHJ40_RS15820 ENOG4105C08 Histidine kinase HHJ40_RS15825 ENOG4105EEX Two component transcriptional regulator (Winged helix family HHJ40_RS15835 ENOG4105CXN decarboxylase HHJ40_RS15840 ENOG4105D5Q Arginine ornithine antiporter HHJ40_RS15845 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HHJ40_RS15850 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HHJ40_RS15855 ENOG4105EV9 Alpha Beta Hydrolase HHJ40_RS15860 ENOG4105NNH LexA regulated protein HHJ40_RS15865 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HHJ40_RS15875 ENOG41090R7 Ferric uptake HHJ40_RS15880 ENOG4105GX6 (LipO)protein HHJ40_RS15895 ENOG4105CI1 PTS System HHJ40_RS15905 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ40_RS15910 ENOG4105E2R ROK family HHJ40_RS15915 ENOG4105D4U had-superfamily hydrolase, subfamily iia HHJ40_RS15920 ENOG4105CAQ asparagine synthetase HHJ40_RS15960 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ40_RS15970 ENOG4105C9A Phoh family HHJ40_RS15980 ENOG4108JU5 Magnesium and cobalt efflux protein HHJ40_RS15985 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HHJ40_RS15995 ENOG4107RP9 extracellular solute-binding protein, family 3 HHJ40_RS16000 ENOG4105EAD ABC transporter HHJ40_RS16005 ENOG4105DRP amino acid AbC transporter HHJ40_RS16010 ENOG4105CDA abc transporter atp-binding protein HHJ40_RS16020 ENOG4105F7F Chaperone HHJ40_RS16025 ENOG4105QFC Hsc56 co-chaperone of HscC HHJ40_RS16030 ENOG41069CF Protein of unknown function (DUF1266) HHJ40_RS16035 ENOG4107JFD Sel1 repeat HHJ40_RS16040 ENOG4105QFC Hsc56 co-chaperone of HscC HHJ40_RS16045 ENOG41069CF Protein of unknown function (DUF1266) HHJ40_RS16050 ENOG4105EUU Sel1 domain protein repeat-containing protein HHJ40_RS16055 ENOG4107PAI alpha helical protein HHJ40_RS16070 ENOG4105DJF DNA polymerase III, delta' subunit HHJ40_RS16080 ENOG4108TGR phosphatase HHJ40_RS16085 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HHJ40_RS16095 ENOG4105CJN penicillin-binding protein HHJ40_RS16100 ENOG4105CNI cell division protein FtsW HHJ40_RS16105 ENOG4105K6T rare lipoprotein A HHJ40_RS16110 ENOG4105DZ1 carboxypeptidase HHJ40_RS16125 ENOG41064T2 transcriptional regulator, lysR family HHJ40_RS16135 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HHJ40_RS16155 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) HHJ40_RS16160 ENOG4105CEE C4-dicarboxylate transporter HHJ40_RS16165 ENOG4106YYS transcriptional regulatory protein HHJ40_RS16170 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ40_RS16175 ENOG4105DUA (citrate (pro-3S)-lyase ligase HHJ40_RS16185 ENOG4105CI0 Citrate lyase HHJ40_RS16190 ENOG4105CHY citrate lyase, alpha HHJ40_RS16205 ENOG4107QPK )-transporter HHJ40_RS16210 ENOG4105KTS ribonuclease HHJ40_RS16215 ENOG4105NXH GreA GreB family elongation factor HHJ40_RS16220 ENOG4105E2A Dehydrogenase HHJ40_RS16225 ENOG4108U51 Universal stress protein HHJ40_RS16230 ENOG4108JU3 Alkyl hydroperoxide reductase HHJ40_RS16235 ENOG4105D3R alkyl hydroperoxide reductase HHJ40_RS16240 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HHJ40_RS16245 ENOG4105DQS Transcriptional regulator HHJ40_RS16250 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HHJ40_RS16255 ENOG4105GTN ParB Domain Protein Nuclease HHJ40_RS16260 ENOG4105CHM Aminotransferase HHJ40_RS16265 ENOG4107SCQ Iron-containing alcohol dehydrogenase HHJ40_RS16270 ENOG4105VCD cytoplasmic protein HHJ40_RS16275 ENOG4105D22 carbon starvation protein HHJ40_RS16280 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HHJ40_RS16285 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HHJ40_RS16290 ENOG4105WQI isochorismatase HHJ40_RS16295 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HHJ40_RS16300 ENOG4105E4F Isochorismate synthase HHJ40_RS16305 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HHJ40_RS16315 ENOG4105DQ5 transport system permease protein HHJ40_RS16320 ENOG4105TVJ transport system, permease HHJ40_RS16325 ENOG4105E0A ABC, transporter HHJ40_RS16330 ENOG4108QY5 Ferric enterobactin transport protein HHJ40_RS16335 ENOG4105C0W non-ribosomal peptide synthetase HHJ40_RS16340 ENOG41085A6 mbth domain-containing protein HHJ40_RS16345 ENOG4105E93 esterase HHJ40_RS16350 ENOG4107RNH Outer membrane receptor FepA HHJ40_RS16355 ENOG4108TSE Transferase HHJ40_RS16365 ENOG4107635 Hok Gef family protein HHJ40_RS16375 ENOG4105WQ6 Membrane HHJ40_RS16380 ENOG4105MSB protein, conserved in bacteria HHJ40_RS16385 ENOG4108RCM Nitroreductase HHJ40_RS16390 ENOG4105CUY Mechanosensitive ion channel HHJ40_RS16395 ENOG4105C85 amino acid HHJ40_RS16400 ENOG4108IJF Heavy metal efflux pump, CzcA HHJ40_RS16405 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HHJ40_RS16410 ENOG410624V efflux system protein HHJ40_RS16415 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HHJ40_RS16420 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ40_RS16425 ENOG4105GR3 Histidine kinase HHJ40_RS16430 ENOG4105CS6 Rhs element vgr protein HHJ40_RS16440 ENOG4105CNA YD repeat protein HHJ40_RS16450 ENOG410600T transposase HHJ40_RS16455 ENOG410802X bacteriophage n4 adsorption protein b HHJ40_RS16460 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HHJ40_RS16465 ENOG4105QUW HHJ40_RS16480 ENOG4108Q9V regulatoR HHJ40_RS16485 ENOG4108ZI2 Fimbrial protein HHJ40_RS16490 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) HHJ40_RS16495 ENOG4105CW0 outer membrane usher protein HHJ40_RS16500 ENOG4108AF8 Chaperone HHJ40_RS16505 ENOG4108WDE Fimbrial protein HHJ40_RS16510 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) HHJ40_RS16515 ENOG4105WQ3 Rna-binding protein HHJ40_RS16520 ENOG4105S2T inner membrane protein YbcI HHJ40_RS16530 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ40_RS16540 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HHJ40_RS16545 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HHJ40_RS16550 ENOG4105C5B carbamate kinase HHJ40_RS16555 ENOG4105G5A Protein of unknown function (DUF2877) HHJ40_RS16560 ENOG4107REC cytoplasmic protein HHJ40_RS16565 ENOG4107R1Q Membrane protein FdrA HHJ40_RS16570 ENOG4105DG4 malate L-lactate dehydrogenase HHJ40_RS16575 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HHJ40_RS16580 ENOG4105S0E allantoin catabolism protein HHJ40_RS16585 ENOG4105BZW Glycerate kinase HHJ40_RS16590 ENOG4105DTE Xanthine uracil vitamin C permease HHJ40_RS16600 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HHJ40_RS16605 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ40_RS16610 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ40_RS16615 ENOG41060W2 glyoxylate carboligase HHJ40_RS16620 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region HHJ40_RS16630 ENOG4107653 Transcriptional regulator HHJ40_RS16665 ENOG4105CV6 ABC transporter, permease HHJ40_RS16670 ENOG4108I0Y (ABC) transporter HHJ40_RS16675 ENOG4108UJV acyl-CoA thioesterase i HHJ40_RS16680 ENOG4105E1F short-chain dehydrogenase reductase HHJ40_RS16690 ENOG4105C4B ABC transporter, permease HHJ40_RS16695 ENOG41083J0 (ABC) transporter HHJ40_RS16700 ENOG4107QX8 SPFH domain, Band 7 family protein HHJ40_RS16705 ENOG4105G5H Membrane HHJ40_RS16710 ENOG4108Z6Z Transcriptional regulator HHJ40_RS16715 ENOG4107RY6 amino acid HHJ40_RS16720 ENOG4105CSV Glutaminase HHJ40_RS16725 ENOG4105C59 p-type ATPase HHJ40_RS16730 ENOG41081XE plasmid maintenance system antidote protein, xre family HHJ40_RS16735 ENOG4105MBR gumn family HHJ40_RS16740 ENOG4108Z66 YbaK ebsC protein HHJ40_RS16745 ENOG4105CGH 5'-nucleotidase HHJ40_RS16750 ENOG4105EU0 Major facilitator Superfamily HHJ40_RS16755 ENOG4105CKD glutathione-regulated potassium-efflux system protein HHJ40_RS16760 ENOG4107RE1 Inosine-guanosine kinase HHJ40_RS16795 ENOG4107QMP dna polymerase iii subunits gamma and tau HHJ40_RS16805 ENOG4105WD1 Membrane HHJ40_RS16810 ENOG4108URS primosomal replication protein n'' HHJ40_RS16815 ENOG4106428 Protein of unknown function (DUF2496) HHJ40_RS16825 ENOG4105EGS Mechanosensitive ion channel HHJ40_RS16830 ENOG4107XI7 Tetr family transcriptional regulator HHJ40_RS16835 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ40_RS16840 ENOG4105BZS acriflavin resistance protein HHJ40_RS16845 ENOG4108UKR Biofilm formation regulator YbaJ HHJ40_RS16850 ENOG4105KF5 hemolysin expression-modulating protein HHJ40_RS16855 ENOG4108UW5 maltose o-acetyltransferase HHJ40_RS16860 ENOG4105GSJ Inner membrane protein ylaC HHJ40_RS16865 ENOG41066DG (EAL) domain protein HHJ40_RS16870 ENOG4105KCV RNA signal recognition particle 4.5S RNA HHJ40_RS16880 ENOG41080UX Methyltransferase HHJ40_RS16885 ENOG4108MNP Glycoprotein polysaccharide metabolism HHJ40_RS16890 ENOG4105C29 acyl-CoA thioesterase HHJ40_RS16895 ENOG4105BZU Histidine kinase HHJ40_RS16900 ENOG4108YZA Nitrogen regulatory protein pii HHJ40_RS16905 ENOG4105BZ1 (ABC) transporter HHJ40_RS16910 ENOG4105BZ1 (ABC) transporter HHJ40_RS16915 ENOG4108XM1 transcriptional regulator AsnC family HHJ40_RS16925 ENOG4108NFA extracellular solute-binding protein HHJ40_RS16935 ENOG4108TGP Thioesterase superfamily protein HHJ40_RS16940 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HHJ40_RS16945 ENOG4105EIN peptidylprolyl cis-trans isomerase HHJ40_RS16950 ENOG4105K70 DNA-binding protein HHJ40_RS16955 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HHJ40_RS16975 ENOG4105M85 Bola protein HHJ40_RS16980 ENOG4105IEY (LipO)protein HHJ40_RS16985 ENOG4105EYM Major Facilitator superfamily HHJ40_RS16990 ENOG4105E2S oxidase) subunit II HHJ40_RS16995 ENOG4105BZ9 Cytochrome C oxidase, subunit I HHJ40_RS17000 ENOG4105CCU oxidase (Subunit III) HHJ40_RS17005 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HHJ40_RS17030 ENOG4107RDB Major Facilitator HHJ40_RS17040 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HHJ40_RS17045 ENOG4107S0N DJ-1 family HHJ40_RS17060 ENOG4105CTB Polyprenyl synthetase HHJ40_RS17070 ENOG4105CPC Aldo Keto reductase HHJ40_RS17075 ENOG4108ZAI phosphatidylglycerophosphatase a HHJ40_RS17080 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HHJ40_RS17090 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) HHJ40_RS17095 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HHJ40_RS17105 ENOG4108KIC (LipO)protein HHJ40_RS17110 ENOG4105DRB nucleoside-specific channel-forming protein HHJ40_RS17115 ENOG4105N1F Hnh endonuclease HHJ40_RS17120 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ40_RS17125 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ40_RS17130 ENOG4105VIE preprotein translocase, subunit YajC HHJ40_RS17150 ENOG4107R28 alpha amylase, catalytic region HHJ40_RS17155 ENOG4105C85 amino acid HHJ40_RS17160 ENOG4105CWM branched-chain amino acid transport system II carrier protein HHJ40_RS17165 ENOG4105BZU Histidine kinase HHJ40_RS17170 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ40_RS17175 ENOG4107RH8 nuclease SbcCD subunit D HHJ40_RS17180 ENOG4105EYH Exonuclease HHJ40_RS17185 ENOG4105F27 Major Facilitator HHJ40_RS17190 ENOG4105DKQ ROK family HHJ40_RS17215 ENOG4105HBA AroM protein HHJ40_RS17220 ENOG4105SS3 HHJ40_RS17235 ENOG4105II7 pyrroline-5-carboxylate reductase HHJ40_RS17240 ENOG4105BZU Histidine kinase HHJ40_RS17245 ENOG4105VIF phosphate starvation-inducible protein HHJ40_RS17250 ENOG4105G6Z alkaline phosphatase HHJ40_RS17265 ENOG4105CPF Cell wall formation (By similarity) HHJ40_RS17270 ENOG4105UNH Membrane HHJ40_RS17275 ENOG4105FR5 inner membrane protein YaiY HHJ40_RS17280 ENOG4107QS8 (LipO)protein HHJ40_RS17285 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HHJ40_RS17290 ENOG4107R6D beta-lactam binding protein AmpH HHJ40_RS17295 ENOG4108PNB DNA-binding transcriptional regulator HHJ40_RS17305 ENOG4105D52 delta-aminolevulinic acid dehydratase HHJ40_RS17310 ENOG4105E2B Taurine dioxygenase HHJ40_RS17315 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HHJ40_RS17325 ENOG4106FTQ Taurine ABC transporter, periplasmic HHJ40_RS17330 ENOG4107W19 lmbE family HHJ40_RS17335 ENOG4108PBI Polysaccharide metabolism HHJ40_RS17345 ENOG4105SRB Uncharacterized protein yaiO HHJ40_RS17365 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HHJ40_RS17405 ENOG4108K2P TRANSCRIPTIONal HHJ40_RS17410 ENOG4105ETE Transcriptional regulator (LacI family HHJ40_RS17420 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HHJ40_RS17425 ENOG4108UW5 maltose o-acetyltransferase HHJ40_RS17430 ENOG4105DJ2 Major Facilitator Superfamily HHJ40_RS17440 ENOG4107B2H carbonic anhydrase HHJ40_RS17445 ENOG4105DND Transcriptional regulator HHJ40_RS17450 ENOG4105DZC cytosine deaminase HHJ40_RS17455 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HHJ40_RS17465 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ40_RS17470 ENOG4105DXD 2-methylcitrate dehydratase HHJ40_RS17475 ENOG4105BZN citrate synthase HHJ40_RS17480 ENOG4105CR4 methylisocitrate lyase HHJ40_RS17485 ENOG4108JU7 Transcriptional regulator HHJ40_RS17490 ENOG4105TDT uncharacterized protein yahO HHJ40_RS17495 ENOG4105E82 cytochrome subunit of dehydrogenase HHJ40_RS17510 ENOG4105DQ4 alcohol dehydrogenase HHJ40_RS17515 ENOG4105CNN ABC, transporter HHJ40_RS17520 ENOG4105CNN ABC, transporter HHJ40_RS17525 ENOG4105C2J ABC transporter HHJ40_RS17530 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ40_RS17540 ENOG4105DZC cytosine deaminase HHJ40_RS17545 ENOG4105C5B carbamate kinase HHJ40_RS17550 ENOG4107REC cytoplasmic protein HHJ40_RS17555 ENOG4107R1Q Membrane protein FdrA HHJ40_RS17560 ENOG4105N16 Protein of unknown function (DUF2877) HHJ40_RS17565 ENOG4107SNB ankyrin repeat protein YahD HHJ40_RS17570 ENOG4105SZ2 membrAne HHJ40_RS17575 ENOG4108NUU Transcriptional regulator HHJ40_RS17580 ENOG4105BZU Histidine kinase HHJ40_RS17590 ENOG4105C94 Transporter HHJ40_RS17615 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HHJ40_RS17620 ENOG4107QR9 Iron-sulfur cluster binding protein HHJ40_RS17625 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ40_RS17630 ENOG4108K01 transcriptional regulator HHJ40_RS17635 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ40_RS17640 ENOG41066GK UPF0379 protein ykgI HHJ40_RS17645 ENOG4108KBJ Inner membrane protein YkgB HHJ40_RS17700 ENOG4108N3D putative enzyme HHJ40_RS17705 ENOG4106PYX Receptor HHJ40_RS17710 ENOG4108UD7 cell wall organization HHJ40_RS17715 ENOG4105PI0 Ferredoxin HHJ40_RS17720 ENOG4105R3P Inner membrane protein yagU HHJ40_RS17725 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit HHJ40_RS17730 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding HHJ40_RS17735 ENOG4105C7W Xanthine dehydrogenase HHJ40_RS17740 ENOG4107XAN XdhC and CoxI family HHJ40_RS17765 ENOG4105FCK Membrane HHJ40_RS17785 ENOG4105CIN aminoacyl-histidine dipeptidase HHJ40_RS17790 ENOG4108S2Y peptide Chain Release factor HHJ40_RS17800 ENOG4108HYG acetyltransferase HHJ40_RS17805 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HHJ40_RS17830 ENOG4108YS0 lipoprotein YafL HHJ40_RS17840 ENOG4105VXN addiction module toxin, RelE StbE family HHJ40_RS17845 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HHJ40_RS17850 ENOG4105E7A Glutamine amidotransferase HHJ40_RS17860 ENOG4107QPN acyl-Coa dehydrogenase HHJ40_RS17865 ENOG4108WN0 inhibitor of vertebrate lysozyme HHJ40_RS17870 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ40_RS17935 ENOG4108WC9 type VI secretion system effector, hcp1 family HHJ40_RS17990 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ40_RS18015 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ40_RS18030 ENOG410600K aminopeptidase HHJ40_RS18040 ENOG4107RZZ dna polymerase iii epsilon subunit HHJ40_RS18050 ENOG4105D1A Methyltransferase HHJ40_RS18060 ENOG4105E9H Lytic Murein transglycosylase HHJ40_RS18065 ENOG4105F2W methyltransferase HHJ40_RS18075 ENOG4105HEI LysR family (Transcriptional regulator HHJ40_RS18080 ENOG4105CV8 reductase HHJ40_RS18115 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HHJ40_RS18120 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HHJ40_RS18125 ENOG4108UMI ABC transporter, permease HHJ40_RS18130 ENOG4105D01 (LipO)protein HHJ40_RS18135 ENOG4108R8X outer membrane lipoprotein HHJ40_RS18140 ENOG4108R96 Methyltransferase, YaeB family HHJ40_RS18150 ENOG4108UY0 (LipO)protein HHJ40_RS18160 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HHJ40_RS18165 ENOG4108YZN class I peptide chain release factor HHJ40_RS18170 ENOG4108VWS Yaeq family HHJ40_RS18180 ENOG4105M1T rho-binding antiterminator HHJ40_RS18185 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HHJ40_RS18190 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HHJ40_RS18195 ENOG4105CXN decarboxylase HHJ40_RS18205 ENOG4105C0B DNA polymerase III (alpha subunit) HHJ40_RS18230 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HHJ40_RS18235 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HHJ40_RS18245 ENOG4105DZP Membrane-associated zinc metalloprotease HHJ40_RS18250 ENOG4105KNE Phosphatidate cytidylyltransferase HHJ40_RS18255 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HHJ40_RS18260 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HHJ40_RS18285 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HHJ40_RS18305 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HHJ40_RS18310 ENOG4105C0H protease HHJ40_RS18325 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HHJ40_RS18330 ENOG4105EN6 Membrane HHJ40_RS18355 ENOG4105S6R Iron-hydroxamate transporter permease subunit HHJ40_RS18360 ENOG4105J76 Periplasmic binding protein HHJ40_RS18365 ENOG4105E0A ABC, transporter HHJ40_RS18370 ENOG4105E0K tonB-dependent siderophore receptor HHJ40_RS18375 ENOG4105BZ4 penicillin-binding protein HHJ40_RS18380 ENOG4105CQ7 ATP-dependent helicase HHJ40_RS18385 ENOG4107XID 2'-5' rna ligase HHJ40_RS18405 ENOG4105DJ0 Poly(A) Polymerase HHJ40_RS18410 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HHJ40_RS18420 ENOG4108VEV chaperone HHJ40_RS18425 ENOG4105CW0 outer membrane usher protein HHJ40_RS18430 ENOG4108XEY fimbrial-like adhesin protein HHJ40_RS18435 ENOG4105SYG Fimbrial protein HHJ40_RS18440 ENOG4105SN2 fimbrial-like adhesin protein HHJ40_RS18445 ENOG4105P0Q fimbrial-like protein YadC HHJ40_RS18460 ENOG4108A32 Transposase HHJ40_RS18470 ENOG4107BJW polysaccharide deacetylase HHJ40_RS18475 ENOG4108YTN IIa component HHJ40_RS18480 ENOG4105E3A (ABC) transporter HHJ40_RS18485 ENOG4105DA5 (ABC) transporter HHJ40_RS18490 ENOG41077A9 carbonic anhydrase HHJ40_RS18495 ENOG4108UGV hypoxanthine phosphoribosyltransferase HHJ40_RS18500 ENOG4105DZG Dehydrogenase HHJ40_RS18510 ENOG4105KME endoribonuclease L-psp HHJ40_RS18525 ENOG4107C93 pyrBI operon leader peptide HHJ40_RS18530 ENOG4108UQ8 endoribonuclease L-psp HHJ40_RS18535 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HHJ40_RS18540 ENOG4108XFH Transcriptional regulator HHJ40_RS18545 ENOG4105XEP YhcH YjgK YiaL family protein HHJ40_RS18560 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HHJ40_RS18565 ENOG4108MJ3 acetyltransferase HHJ40_RS18570 ENOG4108M3P Membrane HHJ40_RS18575 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HHJ40_RS18580 ENOG4105MYG DNA polymerase iii, chi subunit HHJ40_RS18590 ENOG4108M8S permease YjgP YjgQ family protein HHJ40_RS18595 ENOG4108K5H permease YjgP YjgQ family protein HHJ40_RS18600 ENOG4105D7A ATP-binding protein HHJ40_RS18605 ENOG4105DQ4 alcohol dehydrogenase HHJ40_RS18645 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) HHJ40_RS18650 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria HHJ40_RS18665 ENOG4108RQP Major type 1 subunit fimbrin HHJ40_RS18670 ENOG4108S54 Fimbrial protein HHJ40_RS18675 ENOG4108NAE Fimbrial chaperone protein HHJ40_RS18680 ENOG4105CW0 outer membrane usher protein HHJ40_RS18685 ENOG4108SQA Fimbrial HHJ40_RS18690 ENOG4108T65 Fimbrial HHJ40_RS18695 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HHJ40_RS18700 ENOG4107EFN gluconate transport system permease 3 HHJ40_RS18710 ENOG4105DEI Mannitol dehydrogenase HHJ40_RS18715 ENOG4105C6F GntR Family Transcriptional Regulator HHJ40_RS18735 ENOG4107YNJ LysR family Transcriptional regulator HHJ40_RS18740 ENOG4105DYB Isoaspartyl dipeptidase HHJ40_RS18745 ENOG4108P2H Inner membrane protein YjiG HHJ40_RS18750 ENOG41074DU domain protein HHJ40_RS18760 ENOG4105CBP Major Facilitator HHJ40_RS18775 ENOG4105CIZ coA-substrate-specific enzyme activase HHJ40_RS18780 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HHJ40_RS18785 ENOG4106BRA Membrane HHJ40_RS18790 ENOG41083G8 Multidrug resistance protein MdtM HHJ40_RS18805 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HHJ40_RS18810 ENOG4106DIZ Domain of unknown function (DUF1127) HHJ40_RS18820 ENOG4105CKI cobalamin synthesis protein HHJ40_RS18825 ENOG4105VCD cytoplasmic protein HHJ40_RS18830 ENOG4105D22 carbon starvation protein HHJ40_RS18835 ENOG4107UWN reductase HHJ40_RS18840 ENOG4105EFA 4-hydroxyphenylacetate HHJ40_RS18870 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase HHJ40_RS18875 ENOG4105C26 Dehydrogenase HHJ40_RS18880 ENOG4105ERH Fumarylacetoacetate hydrolase HHJ40_RS18885 ENOG4108V8F Transcriptional regulator, MarR family HHJ40_RS18890 ENOG4105C8Q Methyl-accepting chemotaxis HHJ40_RS18895 ENOG4108I5G Major Facilitator superfamily HHJ40_RS18900 ENOG410617M Transcriptional regulator HHJ40_RS18905 ENOG4105CPQ Dehydrogenase HHJ40_RS18920 ENOG4106CVF DNA replication protein HHJ40_RS18935 ENOG4105DWK Membrane HHJ40_RS18940 ENOG4108N8T regulatoR HHJ40_RS18945 ENOG4108T94 DNA-binding transcriptional activator BglJ HHJ40_RS18950 ENOG4108819 ferric iron reductase HHJ40_RS18955 ENOG4105YBH Protein of unknown function (DUF1435) HHJ40_RS18980 ENOG4108WPU DNA polymerase III subunit psi HHJ40_RS18985 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HHJ40_RS18990 ENOG4105PAD Hydrolase HHJ40_RS19000 ENOG4105K3G Periplasmic Protein HHJ40_RS19010 ENOG4108NRW Phospholipase, patatin family HHJ40_RS19015 ENOG4105EYA deoxyribonuclease HHJ40_RS19020 ENOG41076CZ activating enzyme HHJ40_RS19025 ENOG4105G0K glycine radical enzyme YjjI family HHJ40_RS19060 ENOG41062Z9 Membrane HHJ40_RS19065 ENOG4105EAC phosphoserine phosphatase HHJ40_RS19070 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HHJ40_RS19075 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HHJ40_RS19080 ENOG4105C5H ABC transporter HHJ40_RS19085 ENOG4107SC1 transglycosylase HHJ40_RS19095 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ40_RS19105 ENOG4105UEI Transcriptional Regulator AraC Family HHJ40_RS19110 ENOG4108RH0 Crea protein HHJ40_RS19115 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ40_RS19120 ENOG4105EB3 Histidine kinase HHJ40_RS19125 ENOG4105CT7 inner membrane cred family protein HHJ40_RS19130 ENOG41065U4 response regulator HHJ40_RS19135 ENOG410759A HHJ40_RS19140 ENOG4106FVC RNA methyltransferase HHJ40_RS19150 ENOG4105CFH Aspartokinase HHJ40_RS19160 ENOG4105D98 threonine synthase HHJ40_RS19165 ENOG41062C6 Protein of unknown function (DUF2502) HHJ40_RS19180 ENOG4105BZG amino acid carrier protein HHJ40_RS19190 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ40_RS19195 ENOG4106HK8 GPR1 FUN34 yaaH family protein HHJ40_RS19200 ENOG4108QUJ UPF0174 protein YaaW HHJ40_RS19220 ENOG4105WI6 cell killing protein encoded within cryptic prophage HHJ40_RS19230 ENOG41063Z6 transcriptional regulator, lysR family HHJ40_RS19255 ENOG410647N response to DNA damage stimulus HHJ40_RS19260 ENOG4105DTN riboflavin biosynthesis protein ribF HHJ40_RS19265 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) HHJ40_RS19275 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HHJ40_RS19295 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HHJ40_RS19300 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HHJ40_RS19305 ENOG4108XNW Transcriptional activatory protein CaiF HHJ40_RS19315 ENOG4106YT9 Enoyl-CoA hydratase HHJ40_RS19350 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ40_RS19355 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HHJ40_RS19360 ENOG4105C54 Major Facilitator superfamily HHJ40_RS19375 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HHJ40_RS19400 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HHJ40_RS19405 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HHJ40_RS19410 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HHJ40_RS19415 ENOG4105D3G Pseudouridine synthase HHJ40_RS19420 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HHJ40_RS19425 ENOG4105CQ2 DNA polymerase HHJ40_RS19430 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ40_RS19445 ENOG41063TF transcriptional regulator (AraC HHJ40_RS19450 ENOG4108KF1 Membrane HHJ40_RS19460 ENOG4106SMU thiamine transporter membrane protein HHJ40_RS19465 ENOG4105DP9 ABC transporter HHJ40_RS19480 ENOG4105S8Q sugar efflux transporter HHJ40_RS19495 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HHJ40_RS19510 ENOG41064T2 transcriptional regulator, lysR family HHJ40_RS19515 ENOG4105C7K acetolactate synthase HHJ40_RS19520 ENOG4108ZP8 Acetolactate synthase small subunit HHJ40_RS19530 ENOG4107B7Y DNA-binding transcriptional regulator FruR HHJ40_RS19545 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HHJ40_RS19550 ENOG4105CJN penicillin-binding protein HHJ40_RS19555 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HHJ40_RS19560 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HHJ40_RS19575 ENOG4105CNI cell division protein FtsW HHJ40_RS19590 ENOG4105CPF Cell wall formation (By similarity) HHJ40_RS19595 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HHJ40_RS19600 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HHJ40_RS19605 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HHJ40_RS19615 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) HHJ40_RS19625 ENOG4105M6F mutator MutT protein HHJ40_RS19640 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HHJ40_RS19650 ENOG4105D7Q type ii secretion system HHJ40_RS19655 ENOG4107QHF type ii secretion system protein e HHJ40_RS19660 ENOG4108ZUW Major pilin subunit HHJ40_RS19665 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HHJ40_RS19670 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ40_RS19675 ENOG4106A72 regulatory protein AmpE HHJ40_RS19680 ENOG4105C85 amino acid HHJ40_RS19685 ENOG41073TP transcriptional regulator HHJ40_RS19690 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HHJ40_RS19695 ENOG4107QSN dihydrolipoamide acetyltransferase HHJ40_RS19700 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ40_RS19705 ENOG4108NST exported protein HHJ40_RS19710 ENOG4107QIJ Aconitate hydratase 2 HHJ40_RS19730 ENOG4108ZRK uncharacterized protein yacC HHJ40_RS19735 ENOG4105E3B Multicopper oxidase HHJ40_RS19745 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HHJ40_RS19755 ENOG4105D4X repressor HHJ40_RS19760 ENOG4105C5Y PTS System HHJ40_RS19765 ENOG4105CG3 alpha amylase, catalytic region HHJ40_RS19770 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HHJ40_RS19775 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HHJ40_RS19785 ENOG4105CMS peptidase U62, modulator of DNA gyrase HHJ40_RS19795 ENOG4105DFU Cell wall formation (By similarity) HHJ40_RS19810 ENOG4107R9N ABC transporter HHJ40_RS19815 ENOG4105C2J ABC transporter HHJ40_RS19820 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HHJ40_RS19825 ENOG4105F0N pyrophosphate phospho-hydrolase HHJ40_RS19830 ENOG4105MZG transcriptional modulator of maze toxin, mazf HHJ40_RS19835 ENOG41087RY SpoVT_AbrB HHJ40_RS19840 ENOG4108ZHD aig2 family HHJ40_RS19845 ENOG4105MA0 exported protein HHJ40_RS19850 ENOG4105CFU surface antigen HHJ40_RS19860 ENOG4105C37 (CBS) domain HHJ40_RS19865 ENOG41061GZ Protein of unknown function (DUF1107) HHJ40_RS19870 ENOG4108UUE Transcriptional regulator HHJ40_RS19875 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HHJ40_RS19880 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HHJ40_RS19885 ENOG4105KVH Transcriptional regulator HHJ40_RS19890 ENOG4105ECR NmrA family HHJ40_RS19895 ENOG4105DXC membrane HHJ40_RS19905 ENOG4105C85 amino acid HHJ40_RS19910 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ40_RS19915 ENOG4105FHY Opacity-associated protein A HHJ40_RS19925 ENOG4105CHR reductase HHJ40_RS19935 ENOG4105E39 Enoyl-CoA hydratase HHJ40_RS19940 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ40_RS19945 ENOG4107S3R L-aspartate oxidase HHJ40_RS19950 ENOG41069H7 transport system small permease component HHJ40_RS19955 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ40_RS19960 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ40_RS19970 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HHJ40_RS19985 ENOG4105KIT UPF0379 protein yjfY HHJ40_RS20015 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HHJ40_RS20030 ENOG4108MXZ Esterase HHJ40_RS20035 ENOG4105WSB biofilm stress and motility protein A HHJ40_RS20040 ENOG4105S17 UPF0379 protein yjfN HHJ40_RS20045 ENOG4105CSU acyl-Coa dehydrogenase HHJ40_RS20050 ENOG4106032 Glutathionylspermidine synthase HHJ40_RS20055 ENOG4108KXT Conserved Protein HHJ40_RS20060 ENOG4105Z6B inner membrane protein yjfl HHJ40_RS20065 ENOG4107VNS Protein of unknown function (DUF2491) HHJ40_RS20070 ENOG4108P9J Phage shock protein A HHJ40_RS20075 ENOG4105FUX Conserved Protein HHJ40_RS20080 ENOG4105C2N RNA methyltransferase TrmH family group 3 HHJ40_RS20085 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HHJ40_RS20105 ENOG4105EPW hflc protein HHJ40_RS20110 ENOG4107QJR hflk protein HHJ40_RS20115 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HHJ40_RS20130 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) HHJ40_RS20135 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ40_RS20140 ENOG4105K8N protein family UPF0079, ATPase HHJ40_RS20145 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HHJ40_RS20150 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HHJ40_RS20190 ENOG4105EGS Mechanosensitive ion channel HHJ40_RS20195 ENOG4106CG8 Inner membrane protein YjeO HHJ40_RS20200 ENOG4106V5W HHJ40_RS20205 ENOG4107SC7 Inner membrane transporter yjeM HHJ40_RS20215 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ40_RS20220 ENOG4105E33 succinate dehydrogenase HHJ40_RS20235 ENOG41066YJ Beta-lactamase HHJ40_RS20240 ENOG4105QNF Outer membrane lipoprotein HHJ40_RS20245 ENOG4105KPY Small multidrug resistance protein HHJ40_RS20250 ENOG4106BSU Entericidin B HHJ40_RS20255 ENOG4107PEH Entericidin EcnA/B family HHJ40_RS20265 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HHJ40_RS20285 ENOG4108ZVF (LipO)protein HHJ40_RS20300 ENOG4105DVH amino acid HHJ40_RS20305 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HHJ40_RS20310 ENOG4108IJ0 Aspartate ammonia-lyase HHJ40_RS20315 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ40_RS20330 ENOG4108SIC Transcriptional regulator HHJ40_RS20340 ENOG4108M3R transcriptional activator CadC HHJ40_RS20345 ENOG4105D5Q Arginine ornithine antiporter HHJ40_RS20350 ENOG4105CXN decarboxylase HHJ40_RS20355 ENOG4105DUX Transporter HHJ40_RS20360 ENOG4105CRK lysyL-tRNA synthetase HHJ40_RS20375 ENOG410830R acetyltransferase HHJ40_RS20380 ENOG4105VR1 Pfam:DUF1271 HHJ40_RS20385 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ40_RS20390 ENOG4108MRH transcriptional regulatory protein HHJ40_RS20395 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ40_RS20400 ENOG4107GFK fumarate HHJ40_RS20405 ENOG4108R5S membrane HHJ40_RS20410 ENOG4105CT4 transporter HHJ40_RS20415 ENOG4105F8D glycoside hydrolase family 4 HHJ40_RS20420 ENOG4108K2B transcriptional regulator HHJ40_RS20425 ENOG4105CXN decarboxylase HHJ40_RS20430 ENOG4106ZGR Transcriptional regulator HHJ40_RS20435 ENOG4105D5Q Arginine ornithine antiporter HHJ40_RS20440 ENOG4105DIJ Phosphoethanolamine transferase HHJ40_RS20445 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ40_RS20450 ENOG4105ECM Sensor protein basS pmrB HHJ40_RS20460 ENOG4105CSH Transporter HHJ40_RS20465 ENOG4108YIV HHJ40_RS20470 ENOG4108F5E vimentin HHJ40_RS20475 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HHJ40_RS20480 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HHJ40_RS20485 ENOG4105D5T phosphonate abc transporter HHJ40_RS20490 ENOG4105EHI Phosphonate ABC transporter, periplasmic HHJ40_RS20500 ENOG4107RJJ Transcriptional regulator HHJ40_RS20505 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HHJ40_RS20510 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HHJ40_RS20515 ENOG4105EKV Phosphonate metabolism protein HHJ40_RS20520 ENOG4105FT8 Phosphonate metabolism HHJ40_RS20525 ENOG4105ENV phosphonate C-P lyase system protein PhnK HHJ40_RS20530 ENOG4105HRV phosphonate c-p lyase system protein phnl HHJ40_RS20535 ENOG4105FD8 phosphonate metabolism protein PhnM HHJ40_RS20540 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) HHJ40_RS20545 ENOG410849A acetyltransferase, (GNAT) family HHJ40_RS20550 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HHJ40_RS20560 ENOG4108YZG isomerase HHJ40_RS20565 ENOG4105NYY transcriptional regulator, RpiR HHJ40_RS20570 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ40_RS20575 ENOG4105C2J ABC transporter HHJ40_RS20580 ENOG4105CNN ABC, transporter HHJ40_RS20585 ENOG4105UP7 3-epimerase HHJ40_RS20590 ENOG4107TFG D-allose kinase HHJ40_RS20595 ENOG4105EUZ Beta-lactamase domain protein HHJ40_RS20600 ENOG4106833 HHJ40_RS20605 ENOG4105J12 Multidrug resistance protein mdtN HHJ40_RS20610 ENOG4108MI0 Resistance protein HHJ40_RS20615 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ40_RS20625 ENOG41082ND Uncharacterized protein yjcO HHJ40_RS20630 ENOG4105CK2 sodium dicarboxylate symporter HHJ40_RS20635 ENOG4108W0S formate-dependent nitrite reductase complex HHJ40_RS20645 ENOG4108QKW cytochrome c-type biogenesis protein HHJ40_RS20650 ENOG4105DVI reductase, NrfD HHJ40_RS20655 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ40_RS20660 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HHJ40_RS20670 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ40_RS20675 ENOG41062QD Membrane HHJ40_RS20690 ENOG4105EEQ Na H antiporter HHJ40_RS20695 ENOG4105C7N Xanthine uracil vitamin C permease HHJ40_RS20700 ENOG4108Z4X TRANSCRIPTIONal HHJ40_RS20705 ENOG4108W3Q Transcriptional regulator HHJ40_RS20710 ENOG4108M8H domain protein HHJ40_RS20715 ENOG4105PMV Membrane HHJ40_RS20720 ENOG4108UUM single-stranded DNA-binding protein HHJ40_RS20725 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HHJ40_RS20730 ENOG4105MSB protein, conserved in bacteria HHJ40_RS20735 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HHJ40_RS20740 ENOG4105F0S class B acid phosphatase HHJ40_RS20750 ENOG4105CGF Aromatic amino acid aminotransferase HHJ40_RS20755 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ40_RS20760 ENOG4105CDU Replicative dna helicase HHJ40_RS20765 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HHJ40_RS20770 ENOG4105P4Z Phage shock protein G HHJ40_RS20775 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ40_RS20785 ENOG4105MYN Zinc uptake regulation protein HHJ40_RS20790 ENOG4105VDW Csbd family HHJ40_RS20795 ENOG4107R73 Mate efflux family protein HHJ40_RS20805 ENOG41080IJ Diacylglycerol kinase HHJ40_RS20830 ENOG4107W52 maltose operon periplasmic protein HHJ40_RS20840 ENOG4108IJ9 (ABC) transporter HHJ40_RS20845 ENOG4107FKK extracellular solute-binding protein family 1 HHJ40_RS20850 ENOG4105D56 permease protein HHJ40_RS20855 ENOG4105EG2 ABC transporter, permease HHJ40_RS20860 ENOG4107QNK )-transporter HHJ40_RS20875 ENOG4105E3R (LipO)protein HHJ40_RS20880 ENOG4108Q9C Periplasmic Protein HHJ40_RS20885 ENOG4108MDC (LipO)protein HHJ40_RS20900 ENOG4105CFH Aspartokinase HHJ40_RS20905 ENOG4108WZA zeta toxin HHJ40_RS20910 ENOG410756H nucleotidyltransferase HHJ40_RS20920 ENOG4108ZR5 Conserved Protein HHJ40_RS20925 ENOG4105FE9 pseudouridine synthase HHJ40_RS20930 ENOG4105DKT Transcriptional regulator HHJ40_RS20935 ENOG4105CHR reductase HHJ40_RS20940 ENOG4108XCU pts system HHJ40_RS20945 ENOG4105KPI PTS system sorbose subfamily IIB component HHJ40_RS20950 ENOG4105ETZ PTS System HHJ40_RS20955 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ40_RS20960 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HHJ40_RS20970 ENOG4105EAM Na Pi-cotransporter HHJ40_RS20975 ENOG4105C3R Methionine synthase HHJ40_RS20980 ENOG41069M3 Transcriptional regulator HHJ40_RS20995 ENOG4108I9X Isocitrate lyase HHJ40_RS21000 ENOG4107QP3 malate synthase g HHJ40_RS21010 ENOG4105K5X acetyltransferase HHJ40_RS21040 ENOG4105C12 Phosphoribosylglycinamide synthetase HHJ40_RS21045 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ40_RS21050 ENOG4105BZU Histidine kinase HHJ40_RS21055 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HHJ40_RS21060 ENOG4108T8B Protein of unknown function (DUF1481) HHJ40_RS21070 ENOG4105R2J Conserved Protein HHJ40_RS21095 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) HHJ40_RS21105 ENOG4105D06 uba thif-type nad fad binding protein HHJ40_RS21110 ENOG4105WHD thiamine biosynthesis protein ThiS HHJ40_RS21120 ENOG4105D41 biosynthesis protein thiH HHJ40_RS21155 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HHJ40_RS21160 ENOG4105PM1 preprotein translocase subunit SecE HHJ40_RS21195 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HHJ40_RS21225 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) HHJ40_RS21230 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) HHJ40_RS21240 ENOG4108Y73 Membrane HHJ40_RS21245 ENOG4105EJ2 Transcriptional regulator HHJ40_RS21255 ENOG4105C5Q Transcriptional regulator HHJ40_RS21270 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HHJ40_RS21285 ENOG4105DIJ Phosphoethanolamine transferase HHJ40_RS21290 ENOG4106R3P AraC family transcriptional regulator HHJ40_RS21295 ENOG4108XCZ PTS System HHJ40_RS21300 ENOG4108AHH pyruvate formate lyase II activase HHJ40_RS21310 ENOG4108YRF PTS System HHJ40_RS21315 ENOG4105DM4 PTS System HHJ40_RS21320 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ40_RS21325 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ40_RS21330 ENOG4105DCT glycerol dehydrogenase HHJ40_RS21335 ENOG4108XC3 NADH ubiquinone oxidoreductase HHJ40_RS21340 ENOG4108Q5Y Membrane HHJ40_RS21350 ENOG4105SYT Methylenetetrahydrofolate reductase HHJ40_RS21355 ENOG4105CFH Aspartokinase HHJ40_RS21360 ENOG4105C28 cystathionine HHJ40_RS21370 ENOG4107S01 Repressor protein MetJ HHJ40_RS21395 ENOG4105C25 Primosomal protein n' HHJ40_RS21400 ENOG4105ETE Transcriptional regulator (LacI family HHJ40_RS21405 ENOG41063M6 Cell Division Protein HHJ40_RS21420 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HHJ40_RS21435 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ40_RS21445 ENOG4105CBT Fructose-1,6-bisphosphatase HHJ40_RS21450 ENOG4105DP0 ferredoxin-NADP reductase HHJ40_RS21460 ENOG41065TG regulatoR HHJ40_RS21465 ENOG4108VTS Membrane HHJ40_RS21470 ENOG4105EBK exported protein HHJ40_RS21485 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HHJ40_RS21500 ENOG4105FMW periplasmic HHJ40_RS21505 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ40_RS21510 ENOG4105E0F Histidine kinase HHJ40_RS21515 ENOG4108RPX mosc domain containing protein HHJ40_RS21525 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ40_RS21555 ENOG4105C9J Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity) HHJ40_RS21565 ENOG41064BA PTS system, fructose-specific, IIA component HHJ40_RS21570 ENOG4105DM4 PTS System HHJ40_RS21575 ENOG4105CN9 Peptidase m42 family protein HHJ40_RS21580 ENOG4106C3V frv operon regulatory protein HHJ40_RS21585 ENOG4108V87 frv operon regulatory protein HHJ40_RS21600 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ40_RS21605 ENOG4108MG3 formate dehydrogenase HHJ40_RS21615 ENOG41068KX affects formate dehydrogenase-N HHJ40_RS21630 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system HHJ40_RS21640 ENOG4105SUU thioesterase domain HHJ40_RS21655 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HHJ40_RS21665 ENOG4105CSH Transporter HHJ40_RS21675 ENOG4105CPQ Dehydrogenase HHJ40_RS21680 ENOG4105D2M Aldolase HHJ40_RS21685 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ40_RS21690 ENOG4108MGF sugar kinase HHJ40_RS21695 ENOG4105E98 transcriptional regulator DeoR family HHJ40_RS21700 ENOG4105R9B Major Facilitator HHJ40_RS21705 ENOG4108KHF Resistance protein HHJ40_RS21710 ENOG4108K85 Transcriptional regulator HHJ40_RS21715 ENOG4105CI3 gtp-binding protein typa HHJ40_RS21720 ENOG4105C5F glutamine synthetase HHJ40_RS21725 ENOG4105CUX Signal transduction histidine kinase HHJ40_RS21730 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ40_RS21735 ENOG4106FIY HHJ40_RS21740 ENOG4105D4P Coproporphyrinogen iii oxidase HHJ40_RS21755 ENOG4105C2M dna polymerase I HHJ40_RS21760 ENOG4106HNH Acyl-transferase HHJ40_RS21770 ENOG4108Z33 Thiol disulfide Interchange Protein HHJ40_RS21775 ENOG4105E27 serine threonine protein kinase HHJ40_RS21780 ENOG4105PC1 Conserved Protein HHJ40_RS21785 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HHJ40_RS21790 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HHJ40_RS21820 ENOG4108RR8 protoporphyrinogen oxidase HHJ40_RS21825 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HHJ40_RS21830 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HHJ40_RS21840 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HHJ40_RS21850 ENOG4108EX3 reductase HHJ40_RS21855 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HHJ40_RS21860 ENOG4105MDZ Transcriptional activator rfaH HHJ40_RS21870 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HHJ40_RS21875 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HHJ40_RS21880 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HHJ40_RS21890 ENOG4105JC1 sterol-binding domain protein HHJ40_RS21900 ENOG4105CGY Dna recombination protein HHJ40_RS21905 ENOG4108I5U Uridine phosphorylase HHJ40_RS21910 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HHJ40_RS21920 ENOG4105DZ2 Transcriptional regulator HHJ40_RS21925 ENOG4105EMK carboxylate amino acid amine transporter HHJ40_RS21930 ENOG4105DQF Hydrolase HHJ40_RS21935 ENOG4108EUD Lysophospholipase HHJ40_RS21940 ENOG410829K Lysine exporter protein (Lyse ygga) HHJ40_RS21945 ENOG4105CCF Lysine exporter protein (Lyse ygga) HHJ40_RS21950 ENOG4105C9U ATP-dependent DNA helicase RecQ HHJ40_RS21955 ENOG4105HDD phospholipase HHJ40_RS21960 ENOG4108VUY thioesterase Superfamily protein HHJ40_RS21965 ENOG4105FR1 rard protein HHJ40_RS21975 ENOG4107QUT magnesium and cobalt transport protein CorA HHJ40_RS21990 ENOG4107QUT magnesium and cobalt transport protein CorA HHJ40_RS21995 ENOG4108T58 Mg2 transport protein CorA HHJ40_RS22000 ENOG4105C4R Atp-dependent dna helicase HHJ40_RS22005 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HHJ40_RS22015 ENOG4105CT0 Protein of unknown function, DUF484 HHJ40_RS22025 ENOG4105S7Z (LipO)protein HHJ40_RS22050 ENOG4107T0K Adenylate cyclase HHJ40_RS22060 ENOG41076E6 Uroporphyrinogen-III Synthase HHJ40_RS22065 ENOG4105ECF c-methyltransferase HHJ40_RS22070 ENOG410601J HemY protein HHJ40_RS22075 ENOG4105ENH Sulfatase HHJ40_RS22080 ENOG4105C4X radical SAM domain protein HHJ40_RS22105 ENOG4105C85 amino acid HHJ40_RS22125 ENOG4105EGZ biosynthesis protein HHJ40_RS22130 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HHJ40_RS22135 ENOG4108WJ1 acetyltransferase HHJ40_RS22140 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HHJ40_RS22145 ENOG4105C1B dTDP-glucose 4-6-dehydratase HHJ40_RS22150 ENOG4107QQG Dehydrogenase HHJ40_RS22155 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HHJ40_RS22160 ENOG4105SFE lipopolysaccharide biosynthesis protein HHJ40_RS22165 ENOG4105ESV Glycosyl transferase, family 4 HHJ40_RS22170 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HHJ40_RS22195 ENOG4105C4R Atp-dependent dna helicase HHJ40_RS22205 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HHJ40_RS22215 ENOG4105EMY transcriptional regulator HHJ40_RS22220 ENOG4105C7B Threonine dehydratase HHJ40_RS22230 ENOG4105CM2 brancheD-chain amino acid aminotransferase HHJ40_RS22235 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HHJ40_RS22255 ENOG4105C0P Mg chelatase subunit ChlI HHJ40_RS22260 ENOG4108WFC UPF0438 protein yifE HHJ40_RS22300 ENOG4107EJG GntR family transcriptional regulator HHJ40_RS22305 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ40_RS22310 ENOG4105ETE Transcriptional regulator (LacI family HHJ40_RS22315 ENOG4108RVA ribokinase HHJ40_RS22320 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ40_RS22325 ENOG4105CNN ABC, transporter HHJ40_RS22330 ENOG4105C2J ABC transporter HHJ40_RS22360 ENOG4108VVK transcriptional Regulator, AsnC HHJ40_RS22365 ENOG4105QTB Flavodoxin HHJ40_RS22380 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HHJ40_RS22435 ENOG4108RQP Major type 1 subunit fimbrin HHJ40_RS22445 ENOG4105CW0 outer membrane usher protein HHJ40_RS22455 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HHJ40_RS22460 ENOG4105C8U phosphate abc transporter HHJ40_RS22465 ENOG4105E2Z phosphate ABC transporter (Permease HHJ40_RS22470 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HHJ40_RS22475 ENOG4108UTW Plays a role in the regulation of phosphate uptake HHJ40_RS22480 ENOG4105CID antiterminator HHJ40_RS22485 ENOG4105C5Y PTS System HHJ40_RS22490 ENOG4105CS2 ec 3.2.1.21 HHJ40_RS22500 ENOG4105DYC esterase HHJ40_RS22505 ENOG4107VKM 6-phosphogluconolactonase HHJ40_RS22510 ENOG4106611 bacteriocin immunity HHJ40_RS22520 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HHJ40_RS22525 ENOG4105C7N Xanthine uracil vitamin C permease HHJ40_RS22530 ENOG4108YYH Nadph-dependent fmn reductase HHJ40_RS22535 ENOG4105E8Q phosphopantetheinyl transferase HHJ40_RS22550 ENOG4108P6C Tryptophan transporter of low affinity HHJ40_RS22585 ENOG4105VG0 50S ribosomal protein l34 HHJ40_RS22620 ENOG4108FZ9 Chaperone HHJ40_RS22625 ENOG4105CW0 outer membrane usher protein HHJ40_RS22690 ENOG4108BMY protease HHJ40_RS22725 ENOG4105D5K Hemolysin activator protein HHJ40_RS22760 ENOG4106CQM replication HHJ40_RS22770 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) HHJ40_RS22790 ENOG4105KK6 nuclease HHJ40_RS22795 ENOG4107CBI conjugal transfer fertility inhibition protein HHJ40_RS22995 ENOG4105BZU Histidine kinase HHJ40_RS23000 ENOG4105BZU Histidine kinase HHJ40_RS23125 ENOG41073YN Protein of unknown function (DUF1380) HHJ40_RS23160 ENOG4106RMF ParB family