locus-tag class description HHJ44_RS00015 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HHJ44_RS00020 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) HHJ44_RS00025 ENOG4105C1G acyl-Coa dehydrogenase HHJ44_RS00060 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) HHJ44_RS00085 ENOG4108VTW Thioesterase HHJ44_RS00105 ENOG4105UQX Mate efflux family protein HHJ44_RS00115 ENOG4107R11 Transcriptional regulator HHJ44_RS00120 ENOG4106P55 Transcriptional regulator HHJ44_RS00145 ENOG4105FYV Amp nucleosidase HHJ44_RS00150 ENOG4105CSH Transporter HHJ44_RS00160 ENOG4105TNG K13735 adhesin invasin HHJ44_RS00165 ENOG4105TNG K13735 adhesin invasin HHJ44_RS00170 ENOG4105TNG K13735 adhesin invasin HHJ44_RS00175 ENOG4107ZSV Receptor HHJ44_RS00180 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HHJ44_RS00200 ENOG4105C0W non-ribosomal peptide synthetase HHJ44_RS00215 ENOG4105BZ1 (ABC) transporter HHJ44_RS00220 ENOG4105EYM Major Facilitator superfamily HHJ44_RS00285 ENOG4108YX2 DNA-binding protein HHJ44_RS00375 ENOG4105DFP Integrase HHJ44_RS00380 ENOG4108MEK Metal-binding protein YodA HHJ44_RS00385 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) HHJ44_RS00390 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) HHJ44_RS00395 ENOG4105VT2 5-hydroxyisourate hydrolase HHJ44_RS00400 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ44_RS00405 ENOG4107ZY3 Histidine kinase HHJ44_RS00415 ENOG4105ZIT Porin Gram-negative type HHJ44_RS00420 ENOG4105Y0K Inner membrane protein YedR HHJ44_RS00425 ENOG4105EST Metal Dependent Phosphohydrolase HHJ44_RS00430 ENOG4105DVF Cytosine-specific methyltransferase HHJ44_RS00435 ENOG41090BB DNA mismatch endonuclease (vsr) HHJ44_RS00440 ENOG4105FDR Membrane HHJ44_RS00445 ENOG4105CKW Inner membrane protein yedI HHJ44_RS00450 ENOG4105VNZ cytoplasmic protein HHJ44_RS00455 ENOG4105BZU Histidine kinase HHJ44_RS00460 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase HHJ44_RS00465 ENOG4105YX3 cellular response to acidity HHJ44_RS00475 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HHJ44_RS00480 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HHJ44_RS00490 ENOG4105CN7 Flagellar biosynthetic protein FliP HHJ44_RS00495 ENOG4105K0P flagellar biosynthesis protein HHJ44_RS00500 ENOG4105DD5 Flagellar motor switch protein HHJ44_RS00505 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ44_RS00510 ENOG4107ZI8 flagellar basal body-associated protein flil HHJ44_RS00515 ENOG4105WF4 Flagellar hook-length control protein HHJ44_RS00520 ENOG4105GSA Flagellar export protein flij HHJ44_RS00525 ENOG4108JIR Flagellum-specific ATP synthase HHJ44_RS00530 ENOG41090PJ Flagellar assembly protein HHJ44_RS00535 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HHJ44_RS00540 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HHJ44_RS00550 ENOG410814C multidrug resistance protein HHJ44_RS00555 ENOG4108V1U phospholipid-binding protein HHJ44_RS00560 ENOG4108UQN AraC family transcriptional regulator HHJ44_RS00575 ENOG4108RAV Conserved protein HHJ44_RS00585 ENOG41066VF YeeE YedE family protein HHJ44_RS00590 ENOG4108W9D (LipO)protein HHJ44_RS00595 ENOG4105E5K Alpha-amylase HHJ44_RS00605 ENOG4105MQ3 flagellar protein FliS HHJ44_RS00610 ENOG4105DTS flagellar hook-associated HHJ44_RS00615 ENOG4105I03 Flagellin HHJ44_RS00620 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ44_RS00625 ENOG4108M9K flagella biosynthesis protein FliZ HHJ44_RS00630 ENOG4105EAB amino acid AbC transporter HHJ44_RS00640 ENOG4105E5Q amino acid AbC transporter HHJ44_RS00645 ENOG4105CDA abc transporter atp-binding protein HHJ44_RS00650 ENOG4105VJY transcriptional regulator HHJ44_RS00655 ENOG4105XVG cytoplasmic protein HHJ44_RS00665 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ44_RS00695 ENOG4106RHG Yeca family HHJ44_RS00700 ENOG4105E0U tyrosine-specific transport protein HHJ44_RS00705 ENOG4105VVZ metal-binding protein HHJ44_RS00710 ENOG41090A1 ferritin HHJ44_RS00730 ENOG4108UEC Ferritin-like protein HHJ44_RS00735 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HHJ44_RS00745 ENOG4105CNN ABC, transporter HHJ44_RS00750 ENOG4108K4C ec 3.1.3.12 HHJ44_RS00760 ENOG4108VA4 Universal stress protein HHJ44_RS00770 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HHJ44_RS00775 ENOG4107RD7 Flagellar Motor Protein, MotA HHJ44_RS00780 ENOG4105ER2 Ompa motb domain protein HHJ44_RS00785 ENOG4105CBS Chea signal transduction histidine kinase HHJ44_RS00790 ENOG4108V3W Chemotaxis protein, CheW HHJ44_RS00795 ENOG4105C8Q Methyl-accepting chemotaxis HHJ44_RS00805 ENOG4105BZU Histidine kinase HHJ44_RS00810 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) HHJ44_RS00815 ENOG4108VYJ response regulator receiver protein HHJ44_RS00820 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HHJ44_RS00825 ENOG4105D00 flagellar biosynthetic protein flhB HHJ44_RS00830 ENOG4105D7B Flagellar biosynthesis protein flha HHJ44_RS00835 ENOG4105W13 flagellar protein HHJ44_RS00845 ENOG4106ZCM YecM protein HHJ44_RS00855 ENOG4105CUW cytochrome C-TYPE protein HHJ44_RS00860 ENOG4108J2R molybdopterin oxidoreductase HHJ44_RS00875 ENOG4105WJG Glutathione HHJ44_RS00880 ENOG41081XQ Conserved Protein HHJ44_RS00885 ENOG4105D3W isochorismatase HHJ44_RS00895 ENOG4108TIT dATP pyrophosphohydrolase HHJ44_RS00900 ENOG4105CDY transcriptional regulatory protein HHJ44_RS00910 ENOG4107S01 Repressor protein MetJ HHJ44_RS00930 ENOG4105FAV ABC, transporter HHJ44_RS00940 ENOG4105NXV High-affinity zinc uptake system protein HHJ44_RS00945 ENOG4105DR5 peptidase HHJ44_RS00950 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HHJ44_RS00955 ENOG4105CA9 Pyruvate kinase HHJ44_RS00960 ENOG4106KNT transcriptional regulator HHJ44_RS00965 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HHJ44_RS00970 ENOG4105C01 Dihydroxy-acid dehydratase HHJ44_RS00975 ENOG4108UHU Aldolase HHJ44_RS00985 ENOG4105X2V dna damage-inducible protein HHJ44_RS00995 ENOG4108Q2J Inner membrane protein YebE HHJ44_RS01000 ENOG4105CUG Oligopeptidase b HHJ44_RS01005 ENOG4105UMD exodeoxyribonuclease X HHJ44_RS01010 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ44_RS01015 ENOG4105MPK DNA polymerase III subunit theta HHJ44_RS01020 ENOG4105FXM Copper resistance protein HHJ44_RS01025 ENOG4108PNC copper resistance HHJ44_RS01030 ENOG4105NKT exported protein HHJ44_RS01035 ENOG4108R1E Serine threonine protein phosphatase 1 HHJ44_RS01040 ENOG4105UVW uncharacterized protein yebW HHJ44_RS01045 ENOG4105WT8 Protein of unknown function (DUF1480) HHJ44_RS01055 ENOG4105DY2 Paraquat-inducible protein b HHJ44_RS01060 ENOG4105H2K paraquat-inducible protein a HHJ44_RS01065 ENOG4108ZGC gaf domain protein HHJ44_RS01075 ENOG4105CN1 protease HHJ44_RS01085 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ44_RS01090 ENOG4105J4Q Transcriptional regulator HHJ44_RS01095 ENOG4105TIK HHJ44_RS01105 ENOG4105Q3Y exported protein HHJ44_RS01120 ENOG4105DHI Methyltransferase HHJ44_RS01135 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ44_RS01140 ENOG4105ETZ PTS System HHJ44_RS01145 ENOG4105DAS pts system HHJ44_RS01150 ENOG4105EE5 Membrane protein terC HHJ44_RS01155 ENOG4107XTP (EAL) domain protein HHJ44_RS01160 ENOG4105EJQ L-serine dehydratase HHJ44_RS01170 ENOG4105CRQ synthase (Component I) HHJ44_RS01180 ENOG4105V2F Uncharacterized protein yoac HHJ44_RS01185 ENOG4105M4H endoribonuclease L-psp HHJ44_RS01190 ENOG4105DVT helicase HHJ44_RS01195 ENOG41072GX Peptidase M22 Glycoprotease HHJ44_RS01200 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ44_RS01205 ENOG4105CEY Amp-dependent synthetase and ligase HHJ44_RS01210 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HHJ44_RS01215 ENOG4105EJC lysr family transcriptional regulator HHJ44_RS01225 ENOG4108YS1 cytoplasmic protein HHJ44_RS01230 ENOG4105YP6 Domain of unknown function (DUF1869) HHJ44_RS01235 ENOG4105Y3U Transglycosylase-associated protein HHJ44_RS01245 ENOG4106G4W HHJ44_RS01250 ENOG410620I Diguanylate cyclase HHJ44_RS01255 ENOG4105UCG Domain of unknown function (DUF333) HHJ44_RS01260 ENOG4105K78 MarR family Transcriptional regulator HHJ44_RS01265 ENOG4105DJ2 Major Facilitator Superfamily HHJ44_RS01270 ENOG4105R1U AraC Family Transcriptional Regulator HHJ44_RS01285 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HHJ44_RS01290 ENOG4108KHP Diguanylate cyclase HHJ44_RS01295 ENOG4106KTS Inner membrane protein yeaI HHJ44_RS01305 ENOG4105CYN Serine protein kinase HHJ44_RS01310 ENOG4105GNX MltA-interacting MipA family protein HHJ44_RS01315 ENOG4105CV8 reductase HHJ44_RS01320 ENOG4105DSB aldose 1-epimerase HHJ44_RS01325 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ44_RS01335 ENOG4105VUT cytoplasmic protein HHJ44_RS01340 ENOG4105CPQ Dehydrogenase HHJ44_RS01345 ENOG4107TE1 transport protein HHJ44_RS01350 ENOG4105CPQ Dehydrogenase HHJ44_RS01355 ENOG4105D2N Aldolase HHJ44_RS01360 ENOG4107UH8 sugar kinase HHJ44_RS01365 ENOG4105CPC Aldo Keto reductase HHJ44_RS01370 ENOG4105E98 transcriptional regulator DeoR family HHJ44_RS01375 ENOG4108KUU Inner membrane metabolite transport protein ydjE HHJ44_RS01380 ENOG4108RWI nicotinamidase HHJ44_RS01385 ENOG4105HDK L-asparaginase HHJ44_RS01390 ENOG4105D07 Signal peptide peptidase, SppA HHJ44_RS01395 ENOG41069NU Nitroreductase HHJ44_RS01405 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ44_RS01410 ENOG4105D82 Glutamate dehydrogenase HHJ44_RS01415 ENOG4105MTM Protein of unknown function (DUF1496) HHJ44_RS01420 ENOG4105M6F mutator MutT protein HHJ44_RS01425 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HHJ44_RS01430 ENOG4107RM6 sulfurtransferase HHJ44_RS01435 ENOG4108VGW abc transporter atp-binding protein HHJ44_RS01440 ENOG4105CXZ ABC transporter, permease HHJ44_RS01445 ENOG4105VNH ABC transporter solute-binding protein HHJ44_RS01450 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HHJ44_RS01455 ENOG4108N5C SNARE associated Golgi protein-related protein HHJ44_RS01460 ENOG4108KCW iron-sulfur cluster binding HHJ44_RS01465 ENOG4108RSN SNARE associated Golgi HHJ44_RS01470 ENOG4105CGK Exodeoxyribonuclease III HHJ44_RS01500 ENOG4108SPG Periplasmic Protein HHJ44_RS01510 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HHJ44_RS01520 ENOG4105KKI DNA-binding transcriptional activator OsmE HHJ44_RS01525 ENOG4105VZJ PTS System HHJ44_RS01530 ENOG4105CK1 PTS System HHJ44_RS01535 ENOG4105VCP PTS System HHJ44_RS01540 ENOG4105EZV Transcriptional regulator HHJ44_RS01545 ENOG4105F8D glycoside hydrolase family 4 HHJ44_RS01555 ENOG4105CH6 catalase HHJ44_RS01565 ENOG4108ETY sodium dicarboxylate symporter HHJ44_RS01570 ENOG4107K5X Membrane-bound metal-dependent hydrolase HHJ44_RS01575 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HHJ44_RS01580 ENOG4107PN8 YfeABCD locus regulator HHJ44_RS01590 ENOG4105P10 Uncharacterized protein ydiZ HHJ44_RS01595 ENOG4105DE4 1-phosphofructokinase HHJ44_RS01600 ENOG4108NE3 Salt-induced outer membrane protein HHJ44_RS01620 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HHJ44_RS01625 ENOG41082NX 50s ribosomal protein l35 HHJ44_RS01660 ENOG4108V06 Glutathione peroxidase HHJ44_RS01670 ENOG4108QBX (LipO)protein HHJ44_RS01675 ENOG4108TC0 Diguanylate phosphodiesterase HHJ44_RS01690 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ44_RS01700 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HHJ44_RS01705 ENOG4105CEY Amp-dependent synthetase and ligase HHJ44_RS01710 ENOG41090P5 ferredoxin-like protein HHJ44_RS01715 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ44_RS01720 ENOG4105C10 Electron transfer flavoprotein HHJ44_RS01725 ENOG4105CV7 Electron transfer flavoprotein HHJ44_RS01730 ENOG4105W4W Transcriptional regulator HHJ44_RS01735 ENOG4105C1G acyl-Coa dehydrogenase HHJ44_RS01740 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ44_RS01755 ENOG4105EMV Major Facilitator HHJ44_RS01760 ENOG4105EMV Major Facilitator HHJ44_RS01765 ENOG4105SUA Ydil protein HHJ44_RS01775 ENOG4105IPI Membrane HHJ44_RS01780 ENOG4105CQB FAD linked oxidase domain protein HHJ44_RS01785 ENOG4105KA0 thioesterase Superfamily protein HHJ44_RS01790 ENOG410671Z uncharacterized protein ydiH HHJ44_RS01795 ENOG4108Z4V iron-sulfur cluster assembly HHJ44_RS01800 ENOG4105DIW FeS assembly protein SUFB HHJ44_RS01805 ENOG4105C3K feS assembly ATPase SufC HHJ44_RS01810 ENOG4105JRK feS assembly protein SufD HHJ44_RS01825 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ44_RS01830 ENOG4105KMX major outer membrane lipoprotein HHJ44_RS01835 ENOG4105CA9 Pyruvate kinase HHJ44_RS01840 ENOG4105RFR Protein of unknown function (DUF2767) HHJ44_RS01845 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein HHJ44_RS01850 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HHJ44_RS01855 ENOG4105JVW HHJ44_RS01860 ENOG4108393 oxidoreductase Fe-S subunit HHJ44_RS01865 ENOG4108NWD Cytochrome HHJ44_RS01870 ENOG4108Y7C Conserved Protein HHJ44_RS01875 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HHJ44_RS01880 ENOG4105N0V mono-oxygenase ydhR HHJ44_RS01905 ENOG4108R6K riboflavin synthase, subunit alpha HHJ44_RS01910 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HHJ44_RS01915 ENOG4105CZQ inner membrane transport protein YdhC HHJ44_RS01920 ENOG4105F52 Transcriptional regulator HHJ44_RS01935 ENOG4105F27 Major Facilitator HHJ44_RS01940 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ44_RS01945 ENOG4105K4H Nlp p60 protein HHJ44_RS01950 ENOG4105M2J Glutaredoxin HHJ44_RS01960 ENOG4108UYE Lactoylglutathione lyase HHJ44_RS01965 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ44_RS01970 ENOG4108WUH Transcriptional regulator, TetR family HHJ44_RS01975 ENOG4105XZD Fe-S protein HHJ44_RS01980 ENOG4107RGM aldo keto reductase HHJ44_RS01985 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ44_RS01990 ENOG4105DSW Fusaric acid resistance protein HHJ44_RS01995 ENOG4105Y49 secretion protein, HlyD family HHJ44_RS02010 ENOG4108XTF Outer Membrane Lipoprotein HHJ44_RS02020 ENOG410642K Lysozyme inhibitor HHJ44_RS02035 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HHJ44_RS02040 ENOG4108K3A Glutathione S-transferase HHJ44_RS02045 ENOG4105DUX Transporter HHJ44_RS02050 ENOG4105CSM endonuclease III HHJ44_RS02060 ENOG4108UQQ Electron transport complex HHJ44_RS02085 ENOG4105M9B inner membrane protein ydgK HHJ44_RS02090 ENOG4105QZ5 OriC-binding nucleoid-associated protein HHJ44_RS02095 ENOG4106C6R beta-lactam resistance protein HHJ44_RS02100 ENOG4105D9R oxidoreductase HHJ44_RS02110 ENOG4105C87 Aminotransferase class I and II HHJ44_RS02115 ENOG4105CI1 PTS System HHJ44_RS02120 ENOG4107P2S Transcriptional regulator HHJ44_RS02125 ENOG4107ZQV short-chain dehydrogenase reductase HHJ44_RS02130 ENOG4105XEA Tetr family transcriptional regulator HHJ44_RS02135 ENOG4105CNT hydrolase family 2 HHJ44_RS02140 ENOG4105CT4 transporter HHJ44_RS02145 ENOG4108QNI outer membrane porin protein HHJ44_RS02150 ENOG4106J39 exported protein HHJ44_RS02155 ENOG4105EIP mannose-6-phosphate isomerase HHJ44_RS02160 ENOG4107GFK fumarate HHJ44_RS02165 ENOG4105C9Q fumarate hydratase class II HHJ44_RS02175 ENOG4105JJR Histidine kinase HHJ44_RS02180 ENOG4107EXC regulatoR HHJ44_RS02185 ENOG4105RA2 Membrane HHJ44_RS02195 ENOG4105D5Q Arginine ornithine antiporter HHJ44_RS02200 ENOG4105C5D exported protein HHJ44_RS02205 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ44_RS02210 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HHJ44_RS02215 ENOG4105DSF transport protein HHJ44_RS02230 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HHJ44_RS02245 ENOG4105D94 Major Facilitator Superfamily HHJ44_RS02250 ENOG4106NZI LysR family Transcriptional regulator HHJ44_RS02255 ENOG4105DAG ROK family HHJ44_RS02260 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ44_RS02270 ENOG4108NEM leader-binding protein dmsD HHJ44_RS02275 ENOG4107KGK dmso reductase anchor subunit HHJ44_RS02280 ENOG4105QAX Iron-sulfur HHJ44_RS02285 ENOG4105C3J Cysteine desulfurase HHJ44_RS02290 ENOG4107QY8 reductase HHJ44_RS02295 ENOG4105KBG Protein of unknown function (DUF1161) HHJ44_RS02305 ENOG4108MK9 spermidine N(1)-acetyltransferase HHJ44_RS02320 ENOG4105CXK mandelate racemase muconate lactonizing HHJ44_RS02325 ENOG4105CPQ Dehydrogenase HHJ44_RS02340 ENOG4105DEI Mannitol dehydrogenase HHJ44_RS02345 ENOG41061EV selenium-binding protein YdfZ HHJ44_RS02350 ENOG4107XBN GntR Family Transcriptional Regulator HHJ44_RS02355 ENOG4105EMU Dehydrogenase HHJ44_RS02360 ENOG4105DGW oligopeptidase A HHJ44_RS02365 ENOG4108YDI single-species biofilm formation on inanimate substrate HHJ44_RS02370 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria HHJ44_RS02380 ENOG4105E5W Transporter HHJ44_RS02385 ENOG4108594 Permease of the drug metabolite transporter HHJ44_RS02390 ENOG4105FDP GntR family transcriptional regulator HHJ44_RS02400 ENOG4105CK1 PTS System HHJ44_RS02405 ENOG4105VCP PTS System HHJ44_RS02415 ENOG4105CS2 ec 3.2.1.21 HHJ44_RS02420 ENOG4106DNR multiple antibiotic resistance protein HHJ44_RS02425 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HHJ44_RS02430 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HHJ44_RS02450 ENOG4105EGI Transcriptional regulator HHJ44_RS02455 ENOG4105C26 Dehydrogenase HHJ44_RS02460 ENOG4105CSV Glutaminase HHJ44_RS02465 ENOG4105M0C cytoplasmic protein HHJ44_RS02470 ENOG4105BZU Histidine kinase HHJ44_RS02480 ENOG4105FFC UPF0187 protein HHJ44_RS02490 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein HHJ44_RS02495 ENOG4105CAF HipA N-terminal domain protein HHJ44_RS02505 ENOG4105CGD Nad-dependent epimerase dehydratase HHJ44_RS02510 ENOG4108RQP Major type 1 subunit fimbrin HHJ44_RS02520 ENOG4105CW0 outer membrane usher protein HHJ44_RS02525 ENOG4108WDE Fimbrial protein HHJ44_RS02530 ENOG4106318 fimbrial-like protein YdeR HHJ44_RS02535 ENOG4106PIH fimbrial-like protein ydeQ HHJ44_RS02540 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HHJ44_RS02550 ENOG4108NKV transcriptional regulator HHJ44_RS02555 ENOG4105ENH Sulfatase HHJ44_RS02560 ENOG4105C4X radical SAM domain protein HHJ44_RS02570 ENOG4105CQ0 ABC transporter HHJ44_RS02575 ENOG4105PE1 Receptor HHJ44_RS02580 ENOG4107RAN Peptidase, M16 HHJ44_RS02585 ENOG4105CVK Glutamate decarboxylase HHJ44_RS02590 ENOG4105E5D amino acid HHJ44_RS02595 ENOG4105F32 YngK protein HHJ44_RS02600 ENOG4105BZU Histidine kinase HHJ44_RS02600 ENOG4105BZU Histidine kinase HHJ44_RS02605 ENOG4105BZU Histidine kinase HHJ44_RS02610 ENOG4108Z9K Osmotically inducible protein HHJ44_RS02615 ENOG4105TPS biofilm-dependent modulation protein HHJ44_RS02620 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HHJ44_RS02630 ENOG4105DQ4 alcohol dehydrogenase HHJ44_RS02640 ENOG41084S7 Plasmid maintenance system antidote protein HHJ44_RS02645 ENOG4108MG3 formate dehydrogenase HHJ44_RS02650 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ44_RS02660 ENOG4105RPH Inner membrane protein YddG HHJ44_RS02665 ENOG4107QND Nitrite extrusion protein HHJ44_RS02670 ENOG4105CRU nitrate reductase, alpha subunit HHJ44_RS02675 ENOG4108IUE nitrate reductase beta subunit HHJ44_RS02680 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HHJ44_RS02685 ENOG4105D0D Nitrate reductase 2, gamma subunit HHJ44_RS02690 ENOG4105JAB phenazine biosynthesis protein, phzf family HHJ44_RS02695 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HHJ44_RS02700 ENOG4108MEJ flavin reductase domain protein HHJ44_RS02745 ENOG4108N27 Glutathione S-transferase HHJ44_RS02750 ENOG4108N27 Glutathione S-transferase HHJ44_RS02755 ENOG4105C85 amino acid HHJ44_RS02760 ENOG4108NS2 receptor HHJ44_RS02765 ENOG4105CHB tonB-dependent Receptor HHJ44_RS02780 ENOG4108Z7F N-acetyltransferase HHJ44_RS02785 ENOG4108T9Y Inner membrane protein ydcZ HHJ44_RS02790 ENOG4105R71 cytoplasmic protein HHJ44_RS02795 ENOG410654E Membrane HHJ44_RS02810 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HHJ44_RS02815 ENOG4105D81 ABC transporter, permease HHJ44_RS02820 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ44_RS02825 ENOG4107TYH extracellular solute-binding protein family 1 HHJ44_RS02830 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HHJ44_RS02840 ENOG4105RR0 Protein of unknown function (DUF2554) HHJ44_RS02845 ENOG4105CFP Peptidase U32 HHJ44_RS02850 ENOG4108JCI Transcriptional regulator HHJ44_RS02855 ENOG4105DKK Benzoate HHJ44_RS02860 ENOG4108KKZ (LipO)protein HHJ44_RS02865 ENOG41088CC tellurite resistance protein tehB HHJ44_RS02870 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HHJ44_RS02875 ENOG4107WE3 acetyltransferase YdcK HHJ44_RS02880 ENOG4108Z9I -acetyltransferase HHJ44_RS02885 ENOG4105Z2P Protein of unknown function (DUF465) HHJ44_RS02895 ENOG4105E32 cytoplasmic protein HHJ44_RS02900 ENOG4105DDW LysR family Transcriptional regulator HHJ44_RS02910 ENOG4107NK6 Hok/gef family HHJ44_RS02915 ENOG4105UPP uncharacterized protein ydcA HHJ44_RS02920 ENOG4105CPW cytochrome b561 HHJ44_RS02925 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HHJ44_RS02930 ENOG4105C26 Dehydrogenase HHJ44_RS02935 ENOG4107DB1 DUF218 domain HHJ44_RS02940 ENOG4105CQ7 ATP-dependent helicase HHJ44_RS02950 ENOG41077RS Phosphatase HHJ44_RS02955 ENOG4105E8V Alpha Beta Hydrolase Fold protein HHJ44_RS02960 ENOG4108HPI phosphatidate Cytidylyltransferase HHJ44_RS02965 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase HHJ44_RS02970 ENOG4107S5I aldo keto reductase HHJ44_RS02975 ENOG4107EF2 surface-exposed virulence protein HHJ44_RS02980 ENOG4105WXT Conserved Protein HHJ44_RS02985 ENOG410689M (LipO)protein HHJ44_RS02990 ENOG4107H52 Dicarboxylate transport HHJ44_RS02995 ENOG4105C5I Dehydrogenase HHJ44_RS03000 ENOG41090X5 Heat shock protein hslJ HHJ44_RS03005 ENOG4105IKK cytoplasmic protein HHJ44_RS03010 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HHJ44_RS03015 ENOG4105FCK Membrane HHJ44_RS03020 ENOG4108RW8 Universal stress protein F HHJ44_RS03045 ENOG4105C1J atp-dependent rna helicase HHJ44_RS03060 ENOG4105BZU Histidine kinase HHJ44_RS03065 ENOG4108DG9 Smr protein MutS2 HHJ44_RS03080 ENOG4105R1U AraC Family Transcriptional Regulator HHJ44_RS03090 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ44_RS03095 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HHJ44_RS03100 ENOG4105Q9Y Universal stress protein HHJ44_RS03105 ENOG4105S5I Membrane HHJ44_RS03110 ENOG4105D64 Mechanosensitive ion channel HHJ44_RS03115 ENOG4107QSI ABC, transporter HHJ44_RS03120 ENOG4105EQ2 LysR family Transcriptional regulator HHJ44_RS03125 ENOG4105ENX hydrolase HHJ44_RS03140 ENOG4105KXI murein peptide amidase A HHJ44_RS03145 ENOG4107S8C mandelate racemase muconate lactonizing HHJ44_RS03150 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HHJ44_RS03155 ENOG4108JU8 Transcriptional regulator HHJ44_RS03165 ENOG4105CM6 amino acid regulated cytosolic protein HHJ44_RS03170 ENOG4105FKQ transcriptional regulator HHJ44_RS03175 ENOG4107EFV Outer membrane protein G HHJ44_RS03185 ENOG4107URF beta-phospho-glucomutase HHJ44_RS03190 ENOG4105C71 hydrolase family 65, central catalytic HHJ44_RS03195 ENOG4105CK5 oxidoreductase HHJ44_RS03200 ENOG4107TYA transient receptor potential locus HHJ44_RS03205 ENOG4107RRD Dehydrogenase HHJ44_RS03210 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component HHJ44_RS03215 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component HHJ44_RS03220 ENOG4105WEM extracellular solute-binding protein HHJ44_RS03225 ENOG4107QW3 Sucrose phosphorylase HHJ44_RS03230 ENOG4105K8Z Phage shock protein HHJ44_RS03235 ENOG4105NNG Peripheral inner membrane phage-shock protein HHJ44_RS03240 ENOG4105FM1 phage shock protein C HHJ44_RS03245 ENOG4105YYT phage shock protein B HHJ44_RS03250 ENOG41087YS Phage shock protein A HHJ44_RS03255 ENOG4105E51 psp operon transcriptional activator HHJ44_RS03265 ENOG4105N0E Protein of unknown function (DUF2543) HHJ44_RS03270 ENOG4108HIY periplasmic HHJ44_RS03275 ENOG4108I5W peptide transport system, permease protein HHJ44_RS03280 ENOG4108EU3 peptide transport system, permease HHJ44_RS03285 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HHJ44_RS03290 ENOG4108JQ2 peptide transport system atp-binding protein HHJ44_RS03295 ENOG4105C2C drug resistance transporter, Bcr CflA HHJ44_RS03300 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HHJ44_RS03305 ENOG4105BZS acriflavin resistance protein HHJ44_RS03310 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ44_RS03315 ENOG41067SE Tetr family transcriptional regulator HHJ44_RS03320 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HHJ44_RS03325 ENOG4105Q4T oxidoreductase HHJ44_RS03340 ENOG4105BZU Histidine kinase HHJ44_RS03345 ENOG410643D UPF0509 protein HHJ44_RS03350 ENOG4105N2W Transcriptional regulator HHJ44_RS03360 ENOG4108ZJT translation initiation factor, Sui1 HHJ44_RS03370 ENOG4105CFV Tetratricopeptide repeat protein HHJ44_RS03375 ENOG4105Q4A inner membrane protein yciS HHJ44_RS03380 ENOG4105EYK Phosphatidylglycerophosphatase B HHJ44_RS03390 ENOG4107QM5 aconitate hydratase HHJ44_RS03410 ENOG4107R11 Transcriptional regulator HHJ44_RS03415 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HHJ44_RS03420 ENOG4105RKX Protein of unknown function (DUF2498) HHJ44_RS03425 ENOG4105ERU peptidase HHJ44_RS03430 ENOG4105UBK short-chain dehydrogenase reductase HHJ44_RS03435 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HHJ44_RS03440 ENOG4105FE9 pseudouridine synthase HHJ44_RS03445 ENOG4105EG3 transmembrane signal peptide protein HHJ44_RS03450 ENOG4107RTD sua5 ycio yrdc ywlc family protein HHJ44_RS03455 ENOG4105DB7 PHP domain protein HHJ44_RS03465 ENOG4105CRQ synthase (Component I) HHJ44_RS03470 ENOG4108EFP Anthranilate synthase component II HHJ44_RS03475 ENOG4105DK0 Indole-3-glycerol phosphate synthase HHJ44_RS03495 ENOG4108Z9Z response to DNA damage stimulus HHJ44_RS03500 ENOG4108N8X transition metal ion binding HHJ44_RS03520 ENOG4108WF3 methyltransferase HHJ44_RS03525 ENOG4105UZW Tail fiber assembly protein HHJ44_RS03530 ENOG4108X9F tail fiber protein HHJ44_RS03615 ENOG4105IM0 capsid protein HHJ44_RS03655 ENOG41064WM Uncharacterized protein YcgX HHJ44_RS03680 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HHJ44_RS03715 ENOG4105HGD Antitermination protein HHJ44_RS03720 ENOG4105KSK (crossover) junction endodeoxyribonuclease HHJ44_RS03725 ENOG4108MXB Protein of unknown function (DUF968) HHJ44_RS03760 ENOG4108PM0 it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity) HHJ44_RS03800 ENOG4106G8A Qin prophage HHJ44_RS03815 ENOG4108I1J Integrase HHJ44_RS03820 ENOG4105EIF outer membrane protein W HHJ44_RS03840 ENOG4105NAU thioesterase Superfamily protein HHJ44_RS03845 ENOG410822N TonB family HHJ44_RS03850 ENOG4105K9H YciI-like protein HHJ44_RS03855 ENOG4107SVH Potassium channel protein HHJ44_RS03875 ENOG4108JQ7 (ABC) transporter HHJ44_RS03880 ENOG4105C3U ABC transporter HHJ44_RS03885 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ44_RS03890 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ44_RS03895 ENOG4108J59 Extracellular solute-binding protein, family 5 HHJ44_RS03905 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HHJ44_RS03910 ENOG4105C0A alcohol dehydrogenase HHJ44_RS03920 ENOG4107104 thymidine kinase HHJ44_RS03925 ENOG4108SAU DNA-binding protein H-ns HHJ44_RS03930 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ44_RS03935 ENOG4105I93 response regulator HHJ44_RS03940 ENOG4105D78 K07001 NTE family protein HHJ44_RS03950 ENOG4105CIY formyltetrahydrofolate deformylase HHJ44_RS03975 ENOG41076YT nitrate reductase, gamma subunit HHJ44_RS03980 ENOG4105R3A Nitrate reductase HHJ44_RS03985 ENOG4108IUE nitrate reductase beta subunit HHJ44_RS03990 ENOG4105CRU nitrate reductase, alpha subunit HHJ44_RS03995 ENOG4105DQQ Major facilitator superfamily MFS_1 HHJ44_RS04000 ENOG4105BZU Histidine kinase HHJ44_RS04005 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ44_RS04010 ENOG4105ID0 Putative invasin HHJ44_RS04015 ENOG41090EX DsrE family HHJ44_RS04020 ENOG4108NH8 Cation transport protein HHJ44_RS04025 ENOG4105WS7 Cation transport regulator HHJ44_RS04030 ENOG4105EWV Sodium calcium exchanger membrane region HHJ44_RS04045 ENOG41063JG Transcriptional regulator HHJ44_RS04050 ENOG4108YY7 Invasion gene expression up-regulator SirB HHJ44_RS04055 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HHJ44_RS04080 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HHJ44_RS04085 ENOG4105CHH sulfate transporter HHJ44_RS04090 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HHJ44_RS04100 ENOG4105C3G gtp-binding protein HHJ44_RS04110 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HHJ44_RS04115 ENOG4105CMT Dihydroxyacetone kinase HHJ44_RS04120 ENOG4108UTZ Dihydroxyacetone kinase HHJ44_RS04125 ENOG4105VDH Dihydroxyacetone kinase HHJ44_RS04135 ENOG4105S10 periplasmic binding protein HHJ44_RS04140 ENOG4105EHG Permease protein HHJ44_RS04145 ENOG4105E0A ABC, transporter HHJ44_RS04150 ENOG4108BSC Methyltransferase HHJ44_RS04155 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HHJ44_RS04170 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HHJ44_RS04180 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HHJ44_RS04190 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ44_RS04200 ENOG4105ED1 spovr family HHJ44_RS04220 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HHJ44_RS04225 ENOG4105KT5 UmuD protein HHJ44_RS04235 ENOG4108ZZ3 UPF0260 protein HHJ44_RS04240 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HHJ44_RS04250 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HHJ44_RS04255 ENOG4105S66 prophage protein HHJ44_RS04265 ENOG4107QMS site-determining protein HHJ44_RS04300 ENOG410658X HHJ44_RS04320 ENOG410738I uncharacterized protein ymgC HHJ44_RS04330 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB HHJ44_RS04335 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component HHJ44_RS04340 ENOG4105BZU Histidine kinase HHJ44_RS04345 ENOG4108XDN Transcriptional regulator HHJ44_RS04350 ENOG41064WM Uncharacterized protein YcgX HHJ44_RS04360 ENOG4108HMX isocitrate dehydrogenase (NADP) HHJ44_RS04470 ENOG4105IM0 capsid protein HHJ44_RS04495 ENOG4105UZW Tail fiber assembly protein HHJ44_RS04515 ENOG4105QYK bacteriophage lambda Bor protein homolog HHJ44_RS04540 ENOG4105HRS Antitermination protein HHJ44_RS04575 ENOG4105NY2 NinB protein HHJ44_RS04715 ENOG4108I1J Integrase HHJ44_RS04720 ENOG4108HMX isocitrate dehydrogenase (NADP) HHJ44_RS04745 ENOG4107QTF adenylosuccinate lyase HHJ44_RS04750 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ44_RS04755 ENOG4105IFJ Histidine kinase HHJ44_RS04760 ENOG4105EZE Cupin 4 family protein HHJ44_RS04780 ENOG4105D38 putrescine abc transporter HHJ44_RS04785 ENOG4107RUE extracellular solute-binding protein family 1 HHJ44_RS04800 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HHJ44_RS04810 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ44_RS04815 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HHJ44_RS04820 ENOG4105D60 lipoprotein releasing system transmembrane protein HHJ44_RS04825 ENOG4105IQC Inner membrane protein YcfT HHJ44_RS04830 ENOG4108JA2 transcriptioN-repair coupling factor HHJ44_RS04835 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ44_RS04840 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HHJ44_RS04845 ENOG4108IND Tetr family transcriptional regulator HHJ44_RS04850 ENOG4107MBR 17 kDa surface antigen HHJ44_RS04855 ENOG4105CEP NADH dehydrogenase HHJ44_RS04875 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HHJ44_RS04880 ENOG41090DQ Lipoprotein HHJ44_RS04885 ENOG4105K59 histidine triad (HIT) protein HHJ44_RS04890 ENOG4105CNM Receptor HHJ44_RS04895 ENOG4105CI1 PTS System HHJ44_RS04900 ENOG4105F8V Hydrolase, tatD family HHJ44_RS04905 ENOG4107QRG dna polymerase iii HHJ44_RS04915 ENOG4105HHA aminodeoxychorismate lyase HHJ44_RS04920 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HHJ44_RS04925 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ44_RS04930 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ44_RS04935 ENOG4105CHR reductase HHJ44_RS04940 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HHJ44_RS04960 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HHJ44_RS04965 ENOG4108UHJ MAF-like protein HHJ44_RS04970 ENOG4105EI2 Pseudouridine synthase HHJ44_RS04975 ENOG4107QQB Ribonuclease E HHJ44_RS04980 ENOG4105DTJ flagellar hook-associated protein HHJ44_RS04985 ENOG4105E1Q flagellar hook-associated protein HHJ44_RS04990 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HHJ44_RS05005 ENOG4105CGA flagellar basal-body rod protein FlgG HHJ44_RS05010 ENOG4108KPB Flagellar basal-body rod protein FlgF HHJ44_RS05015 ENOG4105BZE flagellar hook protein, FlgE HHJ44_RS05020 ENOG4105W00 Flagellar hook capping protein HHJ44_RS05025 ENOG4108ZC9 flagellar basal-body rod protein flgc HHJ44_RS05030 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HHJ44_RS05035 ENOG4105CKS Flagella basal body P-ring formation protein flgA HHJ44_RS05040 ENOG4105M9M anti-sigma28 factor FlgM HHJ44_RS05045 ENOG4105QVD Flagella synthesis protein FlgN HHJ44_RS05050 ENOG4105CJR Integral membrane protein (MviN HHJ44_RS05055 ENOG4105EP9 oxidoreductase HHJ44_RS05065 ENOG4105D9U N-acetyltransferase HHJ44_RS05075 ENOG4105E9S glutaredoxin 2 HHJ44_RS05080 ENOG4105F3T (LipO)protein HHJ44_RS05090 ENOG4105MEA DNA damage-inducible protein i HHJ44_RS05095 ENOG4105PVA Biofilm formation regulatory protein BssS HHJ44_RS05105 ENOG4106974 biofilm formation HHJ44_RS05110 ENOG4105DS1 cytochrome b561 HHJ44_RS05115 ENOG4108YYC ycei family HHJ44_RS05125 ENOG4105D1S lipid A biosynthesis HHJ44_RS05135 ENOG4108W47 Acidic protein msyB HHJ44_RS05140 ENOG4105NAC (LipO)protein HHJ44_RS05145 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HHJ44_RS05160 ENOG4107RZC phospholipase d HHJ44_RS05165 ENOG4108UVJ appr-1-p processing domain protein HHJ44_RS05180 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HHJ44_RS05185 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HHJ44_RS05190 ENOG41086KC Transcriptional regulator HHJ44_RS05195 ENOG4108XDW curli assembly protein CsgE HHJ44_RS05200 ENOG4108WYR Curli production assembly transport component, CsgF HHJ44_RS05205 ENOG4105P8Q Curli production assembly transport component CsgG HHJ44_RS05210 ENOG4108UQ5 membrane protein YcdZ HHJ44_RS05215 ENOG4107XHZ cytoplasmic chaperone TorD family protein HHJ44_RS05235 ENOG4105BZU Histidine kinase HHJ44_RS05240 ENOG4108TUY outer membrane protein PgaA HHJ44_RS05245 ENOG4107BJW polysaccharide deacetylase HHJ44_RS05250 ENOG4105CND Glycosyl transferase, family 2 HHJ44_RS05260 ENOG4105D5M phosphate starvation-inducible protein HHJ44_RS05275 ENOG4105EKT )-iron permease HHJ44_RS05280 ENOG4105CK7 Sodium proline symporter HHJ44_RS05290 ENOG4105C26 Dehydrogenase HHJ44_RS05295 ENOG4108R86 Transcriptional regulator HHJ44_RS05335 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HHJ44_RS05345 ENOG4105XH3 HHJ44_RS05350 ENOG4105D6F Phosphatase HHJ44_RS05370 ENOG4108EM1 reductase HHJ44_RS05375 ENOG4105CUW cytochrome C-TYPE protein HHJ44_RS05380 ENOG4106WF9 DNA-binding transcriptional regulator TorR HHJ44_RS05385 ENOG4108SV3 Tmao reductase system periplasmic protein tort HHJ44_RS05390 ENOG4105BZU Histidine kinase HHJ44_RS05395 ENOG4105HEE Binding Domain protein HHJ44_RS05400 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HHJ44_RS05415 ENOG4105VEQ Cold shock protein HHJ44_RS05420 ENOG41060EU Cold shock-like protein HHJ44_RS05425 ENOG4105D6F Phosphatase HHJ44_RS05435 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ44_RS05440 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ44_RS05445 ENOG4105MVP hydrogenase-1 operon protein HyaF HHJ44_RS05450 ENOG4108VXY Hydrogenase-1 operon protein HyaE HHJ44_RS05455 ENOG4108USZ hydrogenase HHJ44_RS05460 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HHJ44_RS05465 ENOG4105DPX Hydrogenase, large subunit HHJ44_RS05470 ENOG4105E3S small subunit HHJ44_RS05480 ENOG4108MN8 Membrane HHJ44_RS05485 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HHJ44_RS05505 ENOG4105K4P CoA-binding domain protein HHJ44_RS05520 ENOG41088T4 Helicase IV HHJ44_RS05525 ENOG410901E Membrane HHJ44_RS05530 ENOG4105EM2 membrane HHJ44_RS05535 ENOG4108RZ1 DNA transformation protein HHJ44_RS05545 ENOG4105UYK outer membrane protein a HHJ44_RS05555 ENOG4105DAN ATP-dependent protease HHJ44_RS05565 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HHJ44_RS05570 ENOG4108Q2G (LipO)protein HHJ44_RS05575 ENOG4105DY2 Paraquat-inducible protein b HHJ44_RS05580 ENOG4105F1S paraquat-inducible protein a HHJ44_RS05585 ENOG4105C5H ABC transporter HHJ44_RS05595 ENOG4105QVC MOSC domain-containing protein HHJ44_RS05600 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HHJ44_RS05610 ENOG4108UZX fmn reductase HHJ44_RS05615 ENOG4105GVF (ABC) transporter HHJ44_RS05625 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HHJ44_RS05635 ENOG4105CD8 aminopeptidase N HHJ44_RS05655 ENOG4105CGF Aromatic amino acid aminotransferase HHJ44_RS05660 ENOG4105C5X domain protein HHJ44_RS05665 ENOG4105EAQ (twin-arginine translocation) pathway signal HHJ44_RS05670 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HHJ44_RS05680 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HHJ44_RS05690 ENOG4106371 Methyltransferase HHJ44_RS05695 ENOG4107S90 membrAne HHJ44_RS05700 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HHJ44_RS05715 ENOG4105T0Z Conserved Protein HHJ44_RS05725 ENOG4105BZ1 (ABC) transporter HHJ44_RS05730 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HHJ44_RS05740 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HHJ44_RS05750 ENOG4108K0D peptidase, M48 HHJ44_RS05765 ENOG4107VMU Membrane HHJ44_RS05770 ENOG4105DDY UPF0142 protein ycaO HHJ44_RS05775 ENOG4105TMB Formate nitrite transporter HHJ44_RS05780 ENOG4105C6N Formate acetyltransferase HHJ44_RS05785 ENOG4105F1A Pyruvate formate-lyase HHJ44_RS05795 ENOG4105CHJ isochorismatase hydrolase HHJ44_RS05800 ENOG4107KGK dmso reductase anchor subunit HHJ44_RS05805 ENOG4105QAX Iron-sulfur HHJ44_RS05810 ENOG4107QY8 reductase HHJ44_RS05820 ENOG4105D1H recombination factor protein RarA HHJ44_RS05830 ENOG4105CNU cell division protein FtsK HHJ44_RS05840 ENOG4105C3M thioredoxin reductase HHJ44_RS05845 ENOG4108JJ9 ABC, transporter HHJ44_RS05850 ENOG4108JJ8 (ABC) transporter HHJ44_RS05860 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HHJ44_RS05875 ENOG4105M6W Crispr-associated protein, Csy3 family HHJ44_RS05885 ENOG4105ENG CRISPR-associated protein, Csy1 family HHJ44_RS05890 ENOG4107IIZ CRISPR-associated helicase, Cas3 HHJ44_RS05895 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HHJ44_RS05900 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ44_RS05910 ENOG4105VEQ Cold shock protein HHJ44_RS05920 ENOG4105DJY efflux transporter, rnd family, mfp subunit HHJ44_RS05925 ENOG4108MJ5 VirK protein HHJ44_RS05930 ENOG4105CPB ATP-dependent endonuclease of the OLD family HHJ44_RS05935 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ44_RS05940 ENOG4105DWU Membrane HHJ44_RS05950 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ44_RS05955 ENOG4105C7K acetolactate synthase HHJ44_RS05960 ENOG4105C5W Aldolase HHJ44_RS05965 ENOG4105CGD Nad-dependent epimerase dehydratase HHJ44_RS05970 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HHJ44_RS05975 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ44_RS05985 ENOG41064MM (LipO)protein HHJ44_RS05990 ENOG4105E5Z arginine transporter ATP-binding subunit HHJ44_RS05995 ENOG4106PMH Extracellular solute-binding protein family 3 HHJ44_RS06000 ENOG4105GBT ABC transporter HHJ44_RS06005 ENOG4105DMR ABC, transporter HHJ44_RS06010 ENOG4106TNF Periplasmic binding protein HHJ44_RS06020 ENOG4105RBQ inner membrane protein ybjO HHJ44_RS06025 ENOG4105D38 putrescine abc transporter HHJ44_RS06030 ENOG4105F38 ABC transporter, permease HHJ44_RS06035 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HHJ44_RS06040 ENOG4107RUE extracellular solute-binding protein family 1 HHJ44_RS06045 ENOG4108RMJ sensory transduction regulator HHJ44_RS06055 ENOG4108DBC nitroreductase HHJ44_RS06060 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HHJ44_RS06065 ENOG41090BQ Glutaredoxin HHJ44_RS06070 ENOG4105GWF inner membrane protein YbjM HHJ44_RS06080 ENOG4105ZTC transcriptional activator, Ogr delta HHJ44_RS06120 ENOG4108C33 Resolvase HHJ44_RS06130 ENOG4108US3 tail fiber assembly HHJ44_RS06225 ENOG4105ED4 portal protein HHJ44_RS06255 ENOG4105DFE Dna adenine methylase HHJ44_RS06260 ENOG4105KSC Transcriptional regulator, TraR DksA family HHJ44_RS06285 ENOG4105MEH HHJ44_RS06295 ENOG4105UPP uncharacterized protein ydcA HHJ44_RS06300 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HHJ44_RS06310 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ44_RS06335 ENOG4108PXI ErfK YbiS YcfS YnhG HHJ44_RS06350 ENOG4108YZT Adenosylcobinamide kinase HHJ44_RS06360 ENOG4105GTN ParB Domain Protein Nuclease HHJ44_RS06365 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HHJ44_RS06370 ENOG4107W19 lmbE family HHJ44_RS06375 ENOG4108PBI Polysaccharide metabolism HHJ44_RS06385 ENOG4105SRB Uncharacterized protein yaiO HHJ44_RS06400 ENOG4108RVA ribokinase HHJ44_RS06415 ENOG41080QX K07048 phosphotriesterase-related protein HHJ44_RS06450 ENOG410836F Transposase HHJ44_RS06500 ENOG4108F1U ABC transporter HHJ44_RS06505 ENOG4105EHG Permease protein HHJ44_RS06525 ENOG4108F5E vimentin HHJ44_RS06530 ENOG4108YIV HHJ44_RS06555 ENOG4106549 Antirestriction protein HHJ44_RS06560 ENOG4108YGG dna repair protein HHJ44_RS06570 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ44_RS06605 ENOG4105DR8 Membrane HHJ44_RS06615 ENOG4105DZ1 carboxypeptidase HHJ44_RS06620 ENOG4105CJB Exodeoxyribonuclease I HHJ44_RS06625 ENOG4105CUB amino acid HHJ44_RS06635 ENOG4105EQ1 Transcriptional regulator HHJ44_RS06640 ENOG4107SRH Nad-dependent epimerase dehydratase HHJ44_RS06645 ENOG4105KRQ Addiction module toxin, Txe YoeB family HHJ44_RS06650 ENOG4105VTW prevent-host-death family HHJ44_RS06665 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) HHJ44_RS06675 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HHJ44_RS06680 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HHJ44_RS06695 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase HHJ44_RS06700 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HHJ44_RS06705 ENOG4105C6Y Udp-glucose 6-dehydrogenase HHJ44_RS06710 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HHJ44_RS06750 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase HHJ44_RS06755 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HHJ44_RS06760 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase HHJ44_RS06765 ENOG4105C1B dTDP-glucose 4-6-dehydratase HHJ44_RS06770 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HHJ44_RS06775 ENOG4105G1A colanic acid biosynthesis protein HHJ44_RS06780 ENOG4107T8Q Glycosyl transferase (Group 1 HHJ44_RS06785 ENOG4105C74 pyruvyl transferase HHJ44_RS06790 ENOG4105PSV Polysaccharide Biosynthesis Protein HHJ44_RS06795 ENOG4105D3Q Sugar transferase HHJ44_RS06800 ENOG4107QKV phosphomannomutase HHJ44_RS06805 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HHJ44_RS06810 ENOG4106CD9 glycosyl transferase group 1 HHJ44_RS06815 ENOG4105FGF GDP-mannose mannosyl hydrolase HHJ44_RS06820 ENOG4105C30 Nad-dependent epimerase dehydratase HHJ44_RS06825 ENOG4105C0K Gdp-mannose 4,6-dehydratase HHJ44_RS06830 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HHJ44_RS06835 ENOG4105ECJ Glycosyl Transferase HHJ44_RS06840 ENOG4108NYJ Colanic acid HHJ44_RS06845 ENOG4107RXY Glycosyl transferase HHJ44_RS06850 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HHJ44_RS06855 ENOG41090RK glycosyl transferase HHJ44_RS06860 ENOG4105D75 Capsular exopolysaccharide family HHJ44_RS06865 ENOG4105KJF protein tyrosine phosphatase HHJ44_RS06870 ENOG4105DAY polysaccharide export protein HHJ44_RS06880 ENOG4105EE5 Membrane protein terC HHJ44_RS06895 ENOG4108GAE asmA family HHJ44_RS06905 ENOG4105DBI uridine monophosphokinase HHJ44_RS06910 ENOG4105BZU Histidine kinase HHJ44_RS06915 ENOG4105D03 DNA-3-methyladenine glycosylase II HHJ44_RS06920 ENOG4105R8A Heat shock protein HHJ44_RS06925 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding HHJ44_RS06930 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HHJ44_RS06935 ENOG4108M24 von Willebrand factor, type A HHJ44_RS06970 ENOG4105EB3 Histidine kinase HHJ44_RS06975 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ44_RS06980 ENOG4105KWI UPF0339 protein HHJ44_RS07005 ENOG4105CFP Peptidase U32 HHJ44_RS07010 ENOG41076Z6 Uncharacterized protein yegR HHJ44_RS07025 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HHJ44_RS07030 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ44_RS07035 ENOG41090UW PTS System HHJ44_RS07040 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HHJ44_RS07055 ENOG4105EIE fructose-bisphosphate aldolase HHJ44_RS07060 ENOG4105EAA nucleoside HHJ44_RS07065 ENOG4108KD5 ADP-ribosylation crystallin J1 HHJ44_RS07070 ENOG4108TFM Kinase, PfkB family HHJ44_RS07075 ENOG4105FDP GntR family transcriptional regulator HHJ44_RS07080 ENOG4108UQ1 hydrolase, family 25 HHJ44_RS07085 ENOG4105DWF phosphomethylpyrimidine kinase HHJ44_RS07105 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HHJ44_RS07110 ENOG410662B Type-1 fimbrial protein HHJ44_RS07115 ENOG4105CW0 outer membrane usher protein HHJ44_RS07120 ENOG4108MQF Chaperone HHJ44_RS07125 ENOG41063W2 Fimbrial protein HHJ44_RS07130 ENOG41067AK Protein of unknown function (DUF2574) HHJ44_RS07135 ENOG4105D1F ATP-binding protein HHJ44_RS07145 ENOG4108KDT Molybdate metabolism regulator HHJ44_RS07150 ENOG4108KDT Molybdate metabolism regulator HHJ44_RS07160 ENOG4105KKX ATPase associated with various cellular activities aaa_5 HHJ44_RS07165 ENOG4105RD5 HHJ44_RS07170 ENOG4105DEG Vwa containing coxe family protein HHJ44_RS07175 ENOG410903U zinc ion binding HHJ44_RS07180 ENOG4108YCW (LipO)protein HHJ44_RS07185 ENOG4108W15 Protein of unknown function (DUF1456) HHJ44_RS07190 ENOG4108NEV two component transcriptional regulator, LytTR family HHJ44_RS07195 ENOG4108HRK Histidine kinase HHJ44_RS07200 ENOG4108XDN Transcriptional regulator HHJ44_RS07210 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HHJ44_RS07215 ENOG4108IJ8 ABC transporter HHJ44_RS07220 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HHJ44_RS07225 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HHJ44_RS07230 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HHJ44_RS07235 ENOG4105CXG d-lactate dehydrogenase HHJ44_RS07240 ENOG41061WM D-Alanyl-D-Alanine HHJ44_RS07245 ENOG41069YE inner membrane protein yohC HHJ44_RS07250 ENOG4105KHU inner membrane protein YohD HHJ44_RS07255 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HHJ44_RS07260 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ44_RS07270 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HHJ44_RS07280 ENOG41067MG lrgb family HHJ44_RS07290 ENOG4107GZ4 SanA protein HHJ44_RS07295 ENOG4105Y9N Membrane HHJ44_RS07300 ENOG4105BZ8 glutamate synthase HHJ44_RS07305 ENOG4107SJI Dehydrogenase HHJ44_RS07310 ENOG4108HWV )-transporter HHJ44_RS07315 ENOG4105C2J ABC transporter HHJ44_RS07320 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HHJ44_RS07325 ENOG41060NJ transcriptional regulator HHJ44_RS07330 ENOG4105DHF Membrane HHJ44_RS07345 ENOG4105D05 Receptor HHJ44_RS07350 ENOG4108IQI permease HHJ44_RS07355 ENOG4105DUM transcriptional regulator, lysR family HHJ44_RS07360 ENOG4105HMI Membrane HHJ44_RS07370 ENOG4105DD7 kinase (PfkB family HHJ44_RS07380 ENOG4108Y4K DNA-binding transcriptional activator HHJ44_RS07385 ENOG4105D9N nucleoside HHJ44_RS07390 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HHJ44_RS07395 ENOG4105DD7 kinase (PfkB family HHJ44_RS07400 ENOG4105DM4 PTS System HHJ44_RS07405 ENOG4105DE4 1-phosphofructokinase HHJ44_RS07410 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HHJ44_RS07415 ENOG4105S8Q sugar efflux transporter HHJ44_RS07420 ENOG4105KRS Proteinase inhibitor HHJ44_RS07430 ENOG4105DEI Mannitol dehydrogenase HHJ44_RS07435 ENOG4105CKI cobalamin synthesis protein HHJ44_RS07440 ENOG41076MN Phosphoesterase, PA-phosphatase related HHJ44_RS07445 ENOG4107TT5 NLP P60 protein HHJ44_RS07450 ENOG4105CXC rtn protein HHJ44_RS07455 ENOG4105E43 Extracellular solute-binding protein, family 5 HHJ44_RS07460 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HHJ44_RS07465 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HHJ44_RS07470 ENOG4108JQ5 ABC transporter HHJ44_RS07475 ENOG4105HG6 HHJ44_RS07480 ENOG4105C2C drug resistance transporter, Bcr CflA HHJ44_RS07485 ENOG4105I08 Pseudouridine synthase HHJ44_RS07490 ENOG4105CFI type iii restriction protein res subunit HHJ44_RS07510 ENOG4105E68 Sulfatase HHJ44_RS07520 ENOG4108MGN ATP-binding component of a transport system HHJ44_RS07525 ENOG4108MGN ATP-binding component of a transport system HHJ44_RS07530 ENOG4105WH1 Two component transcriptional regulator luxr family HHJ44_RS07535 ENOG4105KWW Biogenesis protein HHJ44_RS07540 ENOG4107QX9 Thiol disulfide interChange protein HHJ44_RS07545 ENOG4105DA4 cytochrome c-type biogenesis protein HHJ44_RS07555 ENOG4105X3C heme exporter protein HHJ44_RS07560 ENOG41060IM Heme exporter protein HHJ44_RS07565 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HHJ44_RS07575 ENOG4105CUW cytochrome C-TYPE protein HHJ44_RS07580 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HHJ44_RS07585 ENOG4105GXZ Ferredoxin-type protein NapH HHJ44_RS07590 ENOG4108BGM Quinol dehydrogenase periplasmic component HHJ44_RS07600 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HHJ44_RS07605 ENOG4108ZNS ferredoxin-type protein NapF HHJ44_RS07625 ENOG4105IBP Cyclic peptide transporter HHJ44_RS07630 ENOG4105CF1 Alkylated DNA repair protein HHJ44_RS07635 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HHJ44_RS07640 ENOG4105CJ2 (LipO)protein HHJ44_RS07645 ENOG4105FCK Membrane HHJ44_RS07650 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HHJ44_RS07655 ENOG41068CG regulatoR HHJ44_RS07660 ENOG4105BZU Histidine kinase HHJ44_RS07665 ENOG4105BZU Histidine kinase HHJ44_RS07670 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ44_RS07675 ENOG4107QP7 CoA-transferase subunit A HHJ44_RS07680 ENOG4107QNJ CoA-transferase subunit B HHJ44_RS07685 ENOG4105CRW Short chain fatty acid transporter HHJ44_RS07690 ENOG4105CHU acetyl-coa acetyltransferase HHJ44_RS07695 ENOG4105EDV vault protein HHJ44_RS07700 ENOG41081SK signal peptide protein HHJ44_RS07705 ENOG4107S52 alpha-2-macroglobulin domain protein HHJ44_RS07715 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HHJ44_RS07720 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ44_RS07730 ENOG4107GHC outer membrane autotransporter HHJ44_RS07735 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ44_RS07740 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ44_RS07745 ENOG4105XPH Ferredoxin HHJ44_RS07750 ENOG4105FQR PH-inducible protein involved in stress response HHJ44_RS07755 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HHJ44_RS07760 ENOG4105CXY transporter HHJ44_RS07765 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HHJ44_RS07775 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ44_RS07780 ENOG4105DNE Transposase HHJ44_RS07795 ENOG4105CSP Major Facilitator Superfamily HHJ44_RS07805 ENOG4107258 Transcriptional regulator HHJ44_RS07810 ENOG4108EWA cinA-like protein HHJ44_RS07815 ENOG4108UII YfaZ family HHJ44_RS07865 ENOG4106GZG polymyxin resistance protein B HHJ44_RS07870 ENOG4105CEY Amp-dependent synthetase and ligase HHJ44_RS07880 ENOG4108IPT Naphthoate synthase HHJ44_RS07895 ENOG4105E4F Isochorismate synthase HHJ44_RS07900 ENOG4105TNS Conserved Protein HHJ44_RS07905 ENOG4107YB6 acetyltransferase, (GNAT) family HHJ44_RS07915 ENOG4105CP2 von willebrand factor, type a HHJ44_RS07920 ENOG4107VAM peptidase, m28 HHJ44_RS07925 ENOG4105GDX Domain of unknown function (DUF1877) HHJ44_RS07935 ENOG4105C8S subunit m HHJ44_RS07940 ENOG4105D65 subunit l HHJ44_RS07950 ENOG4107UFS subunit j HHJ44_RS07965 ENOG4108IEH NADH dehydrogenase subunit g HHJ44_RS07970 ENOG4107QIZ NADH dehydrogenase HHJ44_RS07975 ENOG4105GKE subunit e HHJ44_RS07995 ENOG4107NQ8 LysR family Transcriptional regulator HHJ44_RS08000 ENOG4105CHM Aminotransferase HHJ44_RS08010 ENOG4107QWE )-transporter HHJ44_RS08015 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HHJ44_RS08020 ENOG4105XWI UPF0304 protein HHJ44_RS08030 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HHJ44_RS08035 ENOG4105C6K Malic enzyme HHJ44_RS08040 ENOG4105CSX c4-dicarboxylate anaerobic carrier HHJ44_RS08045 ENOG4105PTV Nudix Hydrolase HHJ44_RS08050 ENOG4108RE9 Phosphodiesterase HHJ44_RS08055 ENOG4108SHQ Glutathione S-transferase HHJ44_RS08060 ENOG4105CYM Glutathione S-transferase HHJ44_RS08065 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HHJ44_RS08070 ENOG4105ECP epimerase HHJ44_RS08075 ENOG4105DNE Transposase HHJ44_RS08080 ENOG4108JEH abc transporter atp-binding protein HHJ44_RS08085 ENOG4106YG3 ABC transporter HHJ44_RS08090 ENOG4105DSP amino acid AbC transporter HHJ44_RS08095 ENOG4105E89 ABC transporter HHJ44_RS08100 ENOG4105E89 ABC transporter HHJ44_RS08105 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HHJ44_RS08110 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HHJ44_RS08115 ENOG4105E96 Colicin v production protein HHJ44_RS08120 ENOG4108S3P Sporulation domain protein HHJ44_RS08125 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HHJ44_RS08135 ENOG4105DQR SNARE associated Golgi HHJ44_RS08145 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ44_RS08155 ENOG4106WZ1 flagella biosynthesis regulator HHJ44_RS08160 ENOG4105F9N Major Facilitator Superfamily HHJ44_RS08165 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HHJ44_RS08175 ENOG4105MH2 YfcL protein HHJ44_RS08180 ENOG4108BPE -transporting atpase HHJ44_RS08185 ENOG4105EJ9 Membrane HHJ44_RS08215 ENOG4105US4 fimbrial-like protein yfcP HHJ44_RS08220 ENOG4105UGQ Fimbrial HHJ44_RS08225 ENOG4105NEV Fimbrial HHJ44_RS08230 ENOG4108FZ9 Chaperone HHJ44_RS08235 ENOG4106PG1 outer membrane usher protein HHJ44_RS08245 ENOG4108BY2 phosphohistidine phosphatase HHJ44_RS08260 ENOG4105KZW UPF0381 protein HHJ44_RS08265 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HHJ44_RS08270 ENOG410903C (LipO)protein HHJ44_RS08275 ENOG4105S64 Formate nitrite transporter HHJ44_RS08285 ENOG4105W8I Transcriptional regulator HHJ44_RS08300 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ44_RS08305 ENOG4105CW7 secretion protein, HlyD family HHJ44_RS08310 ENOG4108WQH regulatoR HHJ44_RS08315 ENOG4105BZU Histidine kinase HHJ44_RS08320 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HHJ44_RS08325 ENOG4108N2Y auxin Efflux HHJ44_RS08330 ENOG4105CFN oxalyl-CoA decarboxylase HHJ44_RS08340 ENOG4108V08 YfdX protein HHJ44_RS08350 ENOG4105W9M Membrane HHJ44_RS08355 ENOG4105D1S lipid A biosynthesis HHJ44_RS08365 ENOG4105CHM Aminotransferase HHJ44_RS08370 ENOG4108HRK Histidine kinase HHJ44_RS08375 ENOG4105DY9 regulatoR HHJ44_RS08380 ENOG4108CIP transcriptional regulator HHJ44_RS08385 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ44_RS08390 ENOG4105CN9 Peptidase m42 family protein HHJ44_RS08395 ENOG4105DC7 peptidase M24 HHJ44_RS08400 ENOG410863U PTS System HHJ44_RS08405 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ44_RS08420 ENOG4109076 Conserved Protein HHJ44_RS08430 ENOG4105D9N nucleoside HHJ44_RS08435 ENOG4108KMM Diguanylate cyclase HHJ44_RS08450 ENOG4105HZG regulatoR HHJ44_RS08455 ENOG4105GXM Putative transcription regulator (DUF1323) HHJ44_RS08485 ENOG4105CN8 Transcriptional regulator HHJ44_RS08495 ENOG4105EAA nucleoside HHJ44_RS08500 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HHJ44_RS08505 ENOG4108NFH Sugar hydrolase HHJ44_RS08510 ENOG4108M0I Transcriptional regulator HHJ44_RS08515 ENOG4105DHU Bile acid HHJ44_RS08520 ENOG4105VRT cytoplasmic protein HHJ44_RS08540 ENOG4105C6T cysteine synthase HHJ44_RS08550 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ44_RS08555 ENOG4105C5Y PTS System HHJ44_RS08565 ENOG4105M0Y HHJ44_RS08570 ENOG4105C6T cysteine synthase HHJ44_RS08575 ENOG4108IJ6 ABC transporter HHJ44_RS08580 ENOG4105ECW sulfate abc transporter HHJ44_RS08585 ENOG4108I5D sulfate abc transporter HHJ44_RS08590 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HHJ44_RS08595 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HHJ44_RS08610 ENOG4105EZR dyp-type peroxidase family protein HHJ44_RS08615 ENOG4105E7K (LipO)protein HHJ44_RS08620 ENOG4105QZU Inner membrane protein YfeZ HHJ44_RS08630 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HHJ44_RS08640 ENOG4108K3Z AraC family transcriptional regulator HHJ44_RS08645 ENOG4108X49 Ethanolamine utilization protein EutK HHJ44_RS08650 ENOG4106D67 ethanolamine utilization protein HHJ44_RS08660 ENOG4105CPD ethanolamine ammonia-lyase HHJ44_RS08665 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HHJ44_RS08670 ENOG4105ENY Ethanolamine utilization protein eutH HHJ44_RS08675 ENOG4105C0A alcohol dehydrogenase HHJ44_RS08680 ENOG4107RWI ethanolamine utilization protein eutJ HHJ44_RS08685 ENOG4108EKI Dehydrogenase HHJ44_RS08690 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HHJ44_RS08695 ENOG4105KNY Microcompartments protein HHJ44_RS08700 ENOG4107WUY phosphate acetyltransferase HHJ44_RS08705 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HHJ44_RS08710 ENOG4105NDK ethanolamine utilization protein HHJ44_RS08715 ENOG4106S4J ethanolamine utilization protein EutP HHJ44_RS08720 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HHJ44_RS08725 ENOG4105C6K Malic enzyme HHJ44_RS08730 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ44_RS08735 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ44_RS08740 ENOG4108PVD exported protein HHJ44_RS08750 ENOG4105BZ8 glutamate synthase HHJ44_RS08755 ENOG4105BZU Histidine kinase HHJ44_RS08760 ENOG4105BZS acriflavin resistance protein HHJ44_RS08770 ENOG4105KUZ arsenate reductase HHJ44_RS08785 ENOG4106KED esterase YpfH HHJ44_RS08795 ENOG4105CGZ zinc metallopeptidase HHJ44_RS08805 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ44_RS08815 ENOG4105RH4 Glycine cleavage system transcriptional repressor HHJ44_RS08820 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HHJ44_RS08825 ENOG4105C02 permease HHJ44_RS08830 ENOG4105ERG peptidase m48, ste24p HHJ44_RS08835 ENOG4105K89 arsenate reductase HHJ44_RS08840 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HHJ44_RS08845 ENOG4105C2W permease HHJ44_RS08860 ENOG4108V3E phosphoribosylglycinamide formyltransferase HHJ44_RS08865 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HHJ44_RS08870 ENOG4105C9X ppx gppa phosphatase HHJ44_RS08875 ENOG4105BZU Histidine kinase HHJ44_RS08885 ENOG41062G3 Protein of unknown function (DUF2633) HHJ44_RS08890 ENOG4108ZMA Outer membrane lipoprotein HHJ44_RS08895 ENOG41066DY Membrane HHJ44_RS08905 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HHJ44_RS08930 ENOG4105VPD cellular component movement HHJ44_RS08945 ENOG4105N21 Membrane HHJ44_RS08975 ENOG4108JQB penicillin-binding protein 1C HHJ44_RS08980 ENOG4105DN3 alpha-2-macroglobulin domain protein HHJ44_RS08985 ENOG4105KHC sulfurtransferase HHJ44_RS08990 ENOG4105YYA enhanced serine sensitivity protein SseB HHJ44_RS09000 ENOG4105WVQ Fe-S assembly protein IscX HHJ44_RS09005 ENOG4108ZIT Ferredoxin, 2FE-2S HHJ44_RS09025 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HHJ44_RS09045 ENOG4105ECY inositol monophosphatase HHJ44_RS09050 ENOG4107XM9 (LipO)protein HHJ44_RS09055 ENOG4108MN2 Stationary phase inducible protein CsiE HHJ44_RS09060 ENOG4105D8G Major Facilitator superfamily HHJ44_RS09065 ENOG4108SB3 DoxX Family HHJ44_RS09070 ENOG4108ZKT aldose 1-epimerase HHJ44_RS09075 ENOG4105CPQ Dehydrogenase HHJ44_RS09080 ENOG4105CNN ABC, transporter HHJ44_RS09085 ENOG4108F37 ATP-binding component of a transport system HHJ44_RS09090 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HHJ44_RS09095 ENOG4107HQ7 repeat protein HHJ44_RS09100 ENOG4108NZE NAGC-like transcriptional regulator HHJ44_RS09110 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HHJ44_RS09120 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ44_RS09125 ENOG4108SKK alpha helix protein HHJ44_RS09130 ENOG4107WP9 Histidine kinase HHJ44_RS09145 ENOG4108Z6B deaminase HHJ44_RS09150 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HHJ44_RS09155 ENOG4106G6Q Transcriptional regulator HHJ44_RS09160 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HHJ44_RS09175 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HHJ44_RS09195 ENOG4105C3F Signal peptidase i HHJ44_RS09205 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HHJ44_RS09210 ENOG4105VQK sigma E regulatory protein, MucB RseB HHJ44_RS09215 ENOG41069PW sigma-e factor negative regulatory protein HHJ44_RS09220 ENOG4105EMN RNA polymerase sigma factor HHJ44_RS09230 ENOG4108IYU L-aspartate oxidase HHJ44_RS09240 ENOG4105C1J atp-dependent rna helicase HHJ44_RS09245 ENOG41090KR LysR family transcriptional Regulator HHJ44_RS09265 ENOG4105EIB trna rrna methyltransferase HHJ44_RS09270 ENOG4105K63 Thioredoxin HHJ44_RS09275 ENOG4106IUH DTW domain containing protein HHJ44_RS09280 ENOG4105CD5 CoA-binding domain protein HHJ44_RS09285 ENOG4105JIM Phosphatidylserine synthase HHJ44_RS09295 ENOG4105T42 (LipO)protein HHJ44_RS09300 ENOG4105CSH Transporter HHJ44_RS09335 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ44_RS09340 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HHJ44_RS09345 ENOG4105C34 Pseudouridine synthase HHJ44_RS09350 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HHJ44_RS09355 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HHJ44_RS09365 ENOG4105CQC Prephenate dehydratase HHJ44_RS09370 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HHJ44_RS09375 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ44_RS09380 ENOG4105QP9 Protein of unknown function (DUF2799) HHJ44_RS09385 ENOG4108WS1 HHJ44_RS09390 ENOG4108KHX Diguanylate cyclase HHJ44_RS09395 ENOG41090EK ompa motb domain protein HHJ44_RS09420 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HHJ44_RS09425 ENOG4106KVJ cytochrome C assembly protein HHJ44_RS09430 ENOG4108JU6 CBS domain protein HHJ44_RS09445 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HHJ44_RS09450 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HHJ44_RS09460 ENOG4108Z1B Cyclase dehydrase HHJ44_RS09510 ENOG4105PTU response to oxidative stress HHJ44_RS09515 ENOG4108US3 tail fiber assembly HHJ44_RS09520 ENOG4105Y9F tail fiber protein HHJ44_RS09525 ENOG4105Y0G tail protein HHJ44_RS09530 ENOG4108T86 baseplate J family protein HHJ44_RS09550 ENOG4108NKR DNA circulation protein HHJ44_RS09570 ENOG4105TKZ Tail Sheath HHJ44_RS09615 ENOG4105EFC phage portal protein HK97 family HHJ44_RS09625 ENOG4105CAR Terminase, large subunit HHJ44_RS09650 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HHJ44_RS09670 ENOG4105HGD Antitermination protein HHJ44_RS09675 ENOG4108MXB Protein of unknown function (DUF968) HHJ44_RS09685 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HHJ44_RS09715 ENOG4108S1U HHJ44_RS09720 ENOG41078CG DNA-binding transcriptional regulator HHJ44_RS09725 ENOG4105RDA repressor HHJ44_RS09740 ENOG4105H40 HHJ44_RS09745 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) HHJ44_RS09760 ENOG4107R08 Integrase HHJ44_RS09785 ENOG4105D5U fad dependent oxidoreductase HHJ44_RS09790 ENOG4105C26 Dehydrogenase HHJ44_RS09795 ENOG4108JPW Aminotransferase HHJ44_RS09800 ENOG4105C85 amino acid HHJ44_RS09805 ENOG4108PVQ transcriptional regulator HHJ44_RS09810 ENOG4109066 lysm domain bon superfamily protein HHJ44_RS09815 ENOG4105VPI YqaE family transport protein HHJ44_RS09820 ENOG41080HT Transcriptional regulator, arsr family HHJ44_RS09825 ENOG4108V62 Rhodanese domain protein HHJ44_RS09830 ENOG4108X73 DNA- binding protein HHJ44_RS09835 ENOG4108RNS Exports L-alanine (By similarity) HHJ44_RS09840 ENOG4108WMJ Protein of unknown function (DUF2002) HHJ44_RS09845 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HHJ44_RS09855 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HHJ44_RS09860 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HHJ44_RS09870 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ44_RS09875 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ44_RS09880 ENOG4108IJ7 Glycine betaine HHJ44_RS09885 ENOG4108HQS Glycine betaine HHJ44_RS09890 ENOG4105GIJ Glycine betaine HHJ44_RS09895 ENOG4105EQ0 Major Facilitator superfamily HHJ44_RS09900 ENOG4108UMN azlc family HHJ44_RS09905 ENOG4105ZED uncharacterized protein ygaH HHJ44_RS09910 ENOG4105NTK Transcriptional repressor Mpra HHJ44_RS09915 ENOG4105CW7 secretion protein, HlyD family HHJ44_RS09920 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ44_RS09945 ENOG4105W39 Membrane HHJ44_RS09950 ENOG4107VXZ Hydrolase HHJ44_RS09975 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HHJ44_RS09995 ENOG4107TH8 cina domain protein HHJ44_RS10000 ENOG4105CVE Lytic murein transglycosylase HHJ44_RS10005 ENOG410787A Pts system, glucitol sorbitol-specific HHJ44_RS10010 ENOG4105DZY Pts system, glucitol sorbitol-specific HHJ44_RS10015 ENOG4105VI0 Pts system, glucitol sorbitol-specific HHJ44_RS10020 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HHJ44_RS10025 ENOG4105J92 DNA-binding transcriptional activator GutM HHJ44_RS10030 ENOG410804X Transcriptional regulator HHJ44_RS10035 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ44_RS10055 ENOG4105C8H hydrogenase maturation protein Hypf HHJ44_RS10060 ENOG4108RC0 Electron transport protein HHJ44_RS10065 ENOG4105DDV Transcriptional regulator (LacI family HHJ44_RS10070 ENOG4105C5Y PTS System HHJ44_RS10075 ENOG4105CS2 ec 3.2.1.21 HHJ44_RS10080 ENOG4108Z3N Transcriptional regulator HHJ44_RS10090 ENOG4108MG9 hydrogenase 3 maturation protease HHJ44_RS10095 ENOG4105I6X formate hydrogenlyase maturation HHJ44_RS10100 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HHJ44_RS10105 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HHJ44_RS10110 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HHJ44_RS10115 ENOG4107TDF Formate hydrogenlyase subunit 4 HHJ44_RS10120 ENOG4107R30 NADH dehydrogenase HHJ44_RS10125 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HHJ44_RS10130 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HHJ44_RS10135 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HHJ44_RS10140 ENOG4107RSS Hydrogenase accessory protein HypB HHJ44_RS10145 ENOG41083WG hydrogenase assembly chaperone HHJ44_RS10150 ENOG4105CQS hydrogenase expression formation protein HypD HHJ44_RS10155 ENOG4105C45 hydrogenase expression formation protein (HypE) HHJ44_RS10160 ENOG4108JUA Transcriptional regulator HHJ44_RS10170 ENOG4105VXR cytoplasmic protein HHJ44_RS10180 ENOG4105MEW serine threonine protein phosphatase HHJ44_RS10185 ENOG4105MVE transcriptional regulator HHJ44_RS10195 ENOG4105G63 Type III effector Hrp-dependent HHJ44_RS10205 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ44_RS10210 ENOG4105C6Z Gluconate HHJ44_RS10225 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ44_RS10230 ENOG4108K5P (LipO)protein HHJ44_RS10265 ENOG4105N0Z inner membrane protein ygbE HHJ44_RS10285 ENOG4108MXK alkaline phosphatase isozyme conversion HHJ44_RS10290 ENOG4107635 Hok Gef family protein HHJ44_RS10310 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HHJ44_RS10315 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ44_RS10320 ENOG4105WQV ferredoxin-like protein HHJ44_RS10325 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator HHJ44_RS10330 ENOG4105YBM electron transfer flavoprotein subunit ygcQ HHJ44_RS10335 ENOG4106IKH Electron transfer flavoprotein HHJ44_RS10340 ENOG4105C54 Major Facilitator superfamily HHJ44_RS10345 ENOG4107R3A FAD linked oxidase domain protein HHJ44_RS10350 ENOG4105CHR reductase HHJ44_RS10355 ENOG4108ITV Inner membrane protein yqcE HHJ44_RS10360 ENOG4108CWB sugar kinase ygcE HHJ44_RS10365 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HHJ44_RS10375 ENOG4105HA9 of methanol dehydrogenase type HHJ44_RS10385 ENOG4105HA9 of methanol dehydrogenase type HHJ44_RS10400 ENOG4105DXN mazG family HHJ44_RS10405 ENOG4105MZG transcriptional modulator of maze toxin, mazf HHJ44_RS10410 ENOG4106A2Z transcriptional regulator antitoxin, MazE HHJ44_RS10415 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ44_RS10425 ENOG4105BZU Histidine kinase HHJ44_RS10430 ENOG4105EQX glucarate dehydratase HHJ44_RS10435 ENOG4105EQX glucarate dehydratase HHJ44_RS10440 ENOG4105DJB Major Facilitator Superfamily HHJ44_RS10445 ENOG4105QDK Flavodoxin HHJ44_RS10450 ENOG4105DR9 pseudouridine synthase HHJ44_RS10455 ENOG4105WP7 tRNA pseudouridine synthase C HHJ44_RS10470 ENOG4105EWT decarboxylase family HHJ44_RS10475 ENOG4105C44 Serine transporter HHJ44_RS10480 ENOG4105EJQ L-serine dehydratase HHJ44_RS10490 ENOG4105C0A alcohol dehydrogenase HHJ44_RS10495 ENOG4107W7X Aldolase HHJ44_RS10500 ENOG4105EDR glucose galactose transporter HHJ44_RS10510 ENOG4105CMG Carbohydrate kinase HHJ44_RS10520 ENOG4107EDW L-fucose operon activator HHJ44_RS10530 ENOG4105M08 Membrane HHJ44_RS10535 ENOG4105ETT transcriptional Regulator, LysR family HHJ44_RS10540 ENOG4105M5B (LipO)protein HHJ44_RS10545 ENOG4105C9B Cysteine desulfurase HHJ44_RS10550 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HHJ44_RS10555 ENOG4105CUZ uba thif-type nad fad binding protein HHJ44_RS10560 ENOG4105CA3 membrane-bound lytic murein transglycosylase HHJ44_RS10600 ENOG4108ZG0 Ompa motb domain protein HHJ44_RS10610 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ44_RS10700 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ44_RS10705 ENOG4105C87 Aminotransferase class I and II HHJ44_RS10710 ENOG4105CI1 PTS System HHJ44_RS10715 ENOG4105CID antiterminator HHJ44_RS10720 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ44_RS10725 ENOG4108EKC n-acetylglutamate synthase HHJ44_RS10730 ENOG4107QYX exodeoxyribonuclease v alpha HHJ44_RS10735 ENOG4107QKA exodeoxyribonuclease V beta HHJ44_RS10740 ENOG4107QXK peptidase HHJ44_RS10745 ENOG4105DSY exodeoxyribonuclease V, gamma HHJ44_RS10750 ENOG4105RVB Prepilin peptidase dependent protein c HHJ44_RS10755 ENOG4105SEN Protein of unknown function (DUF2509) HHJ44_RS10760 ENOG4105JCS prepilin peptidase dependent protein HHJ44_RS10765 ENOG4105IPU prepilin peptidase dependent protein A HHJ44_RS10780 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HHJ44_RS10795 ENOG4105EE5 Membrane protein terC HHJ44_RS10800 ENOG4105SUV lipoprotein YgdR HHJ44_RS10805 ENOG4105CPC Aldo Keto reductase HHJ44_RS10820 ENOG41060NJ transcriptional regulator HHJ44_RS10830 ENOG4105RQF LysR family Transcriptional regulator HHJ44_RS10840 ENOG4107QNK )-transporter HHJ44_RS10845 ENOG4105CHR reductase HHJ44_RS10855 ENOG4105CHU acetyl-coa acetyltransferase HHJ44_RS10860 ENOG4108MHD transport protein HHJ44_RS10870 ENOG4108K5P (LipO)protein HHJ44_RS10875 ENOG4105C7W Xanthine dehydrogenase HHJ44_RS10880 ENOG4108HR6 Dehydrogenase HHJ44_RS10885 ENOG4108UTP (2Fe-2S)-binding domain protein HHJ44_RS10890 ENOG4108JUB Transcriptional regulator HHJ44_RS10895 ENOG4105IW6 Carbamoyltransferase HHJ44_RS10900 ENOG4107RCH Diaminopropionate ammonia-lyase HHJ44_RS10905 ENOG4107S4Y M20 DapE family protein YgeY HHJ44_RS10915 ENOG4105C5B carbamate kinase HHJ44_RS10920 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HHJ44_RS10925 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HHJ44_RS10930 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HHJ44_RS10935 ENOG4105BZ8 glutamate synthase HHJ44_RS10940 ENOG4107UUR Chlorohydrolase aminohydrolase HHJ44_RS10945 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HHJ44_RS10950 ENOG4105C7W Xanthine dehydrogenase HHJ44_RS10955 ENOG4105C2W permease HHJ44_RS10960 ENOG4107QUY Guanine deaminase HHJ44_RS10965 ENOG4105C7N Xanthine uracil vitamin C permease HHJ44_RS10970 ENOG4108R8B oxidoreductase Fe-S subunit HHJ44_RS10975 ENOG4105BZ8 glutamate synthase HHJ44_RS10980 ENOG4105C2W permease HHJ44_RS11000 ENOG4105CRK lysyL-tRNA synthetase HHJ44_RS11010 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HHJ44_RS11015 ENOG4105T95 Thiol disulfide interChange protein HHJ44_RS11020 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HHJ44_RS11025 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HHJ44_RS11030 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HHJ44_RS11035 ENOG4105Y75 tpr repeat protein HHJ44_RS11045 ENOG4108UT2 hemolysin iii HHJ44_RS11055 ENOG4105CS2 ec 3.2.1.21 HHJ44_RS11080 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ44_RS11085 ENOG4105D0A hydroxylase HHJ44_RS11090 ENOG4107RAQ aminopeptidase HHJ44_RS11110 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HHJ44_RS11120 ENOG4108JQ1 Dehydrogenase HHJ44_RS11140 ENOG4105D5P Methylmalonyl-coA mutase HHJ44_RS11145 ENOG4105DEQ transcriptional regulator HHJ44_RS11150 ENOG4105MPN Membrane HHJ44_RS11155 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HHJ44_RS11160 ENOG4105D64 Mechanosensitive ion channel HHJ44_RS11165 ENOG4105D2N Aldolase HHJ44_RS11200 ENOG4108JJB ABC transporter HHJ44_RS11205 ENOG4107Z1W Fructose transport system kinase HHJ44_RS11210 ENOG4108R4K DNA-binding, transcriptional regulator HHJ44_RS11220 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HHJ44_RS11225 ENOG4105CTS PTS system mannitol-specific HHJ44_RS11230 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HHJ44_RS11235 ENOG4105EPW hflc protein HHJ44_RS11240 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ44_RS11245 ENOG4108K0D peptidase, M48 HHJ44_RS11260 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HHJ44_RS11280 ENOG4107QNK )-transporter HHJ44_RS11290 ENOG4105RWS endonuclease I HHJ44_RS11295 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HHJ44_RS11300 ENOG4105D7Z glutathione synthase HHJ44_RS11315 ENOG4105CZX twitching motility protein HHJ44_RS11320 ENOG4105DFA alanine racemase domain protein HHJ44_RS11325 ENOG4108VIA integral membrane protein HHJ44_RS11335 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ44_RS11340 ENOG4105CSA Coproporphyrinogen iii oxidase HHJ44_RS11345 ENOG4106MH3 alpha helix chain HHJ44_RS11350 ENOG4105HDK L-asparaginase HHJ44_RS11355 ENOG4105K33 Periplasmic Protein HHJ44_RS11360 ENOG41090ED Protein with unknown function (DUF469) HHJ44_RS11370 ENOG4105CEN a g-specific adenine glycosylase HHJ44_RS11385 ENOG4105EAA nucleoside HHJ44_RS11390 ENOG4105CXN decarboxylase HHJ44_RS11395 ENOG4108UQV Membrane HHJ44_RS11415 ENOG4108I6E Sulfatase HHJ44_RS11420 ENOG4105T40 surface antigen msp4 family protein HHJ44_RS11440 ENOG4106CXJ Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 sp P42190 PAPK_ECOLI PROTEIN PAPK PRECURSOR HHJ44_RS11450 ENOG4106P2F Pfam:Pili_assembly_C HHJ44_RS11455 ENOG4106PG1 outer membrane usher protein HHJ44_RS11460 ENOG4108ZJG MrfB protein HHJ44_RS11510 ENOG4105CXY transporter HHJ44_RS11515 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC HHJ44_RS11525 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta HHJ44_RS11555 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HHJ44_RS11580 ENOG4105D05 Receptor HHJ44_RS11605 ENOG4105TS0 gtp-binding protein HHJ44_RS11610 ENOG4108KZE transcriptional regulator HHJ44_RS11625 ENOG4106H6R UPF0380 protein HHJ44_RS11630 ENOG4105MFG Antirestriction protein HHJ44_RS11635 ENOG4108YGG dna repair protein HHJ44_RS11645 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ44_RS11670 ENOG4105BZU Histidine kinase HHJ44_RS11680 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ44_RS11685 ENOG4105ECX polysaccharide export HHJ44_RS11690 ENOG4107V1M polysaccharide export protein HHJ44_RS11695 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) HHJ44_RS11700 ENOG4105E12 capsule polysaccharide HHJ44_RS11705 ENOG41084CK capsule polysaccharide HHJ44_RS11740 ENOG4105U1E general secretion pathway protein M HHJ44_RS11760 ENOG4105X5Z General secretion pathway protein I HHJ44_RS11770 ENOG4108VAU general secretion pathway protein G HHJ44_RS11775 ENOG4105D7Q type ii secretion system HHJ44_RS11780 ENOG4107QHF type ii secretion system protein e HHJ44_RS11790 ENOG4108XKW General secretion pathway protein C HHJ44_RS11795 ENOG410765S (LipO)protein HHJ44_RS11805 ENOG4105F88 accessory colonization factor AcfD HHJ44_RS11810 ENOG4105DAA L-lactate HHJ44_RS11815 ENOG4107QP3 malate synthase g HHJ44_RS11820 ENOG4108ZJF Glcg protein HHJ44_RS11825 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ44_RS11830 ENOG4105EU8 FAD linked oxidase domain protein HHJ44_RS11835 ENOG4105CQB FAD linked oxidase domain protein HHJ44_RS11840 ENOG4108KWP DNA-binding transcriptional regulator GlcC HHJ44_RS11850 ENOG4107RCI amp-dependent synthetase and ligase HHJ44_RS11860 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HHJ44_RS11865 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ44_RS11875 ENOG4108M8S permease YjgP YjgQ family protein HHJ44_RS11880 ENOG4108UUE Transcriptional regulator HHJ44_RS11890 ENOG4108S55 polysaccharide biosynthesis protein HHJ44_RS11895 ENOG4106FPV ATP-binding protein YghR HHJ44_RS11900 ENOG4108NDC ATP-binding protein yghS HHJ44_RS11905 ENOG4108GH0 ATP-binding protein yghT HHJ44_RS11910 ENOG4105CJ3 phosphate transporter HHJ44_RS11915 ENOG4106032 Glutathionylspermidine synthase HHJ44_RS11920 ENOG4105CYM Glutathione S-transferase HHJ44_RS11925 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HHJ44_RS11930 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HHJ44_RS11935 ENOG4108WGS hydrogenase 2-specific chaperone HHJ44_RS11940 ENOG4108USZ hydrogenase HHJ44_RS11945 ENOG4105DPX Hydrogenase, large subunit HHJ44_RS11950 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HHJ44_RS11955 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ44_RS11960 ENOG4105E3S small subunit HHJ44_RS11965 ENOG410900S Protein of unknown function (DUF2623) HHJ44_RS11975 ENOG4105CPC Aldo Keto reductase HHJ44_RS11985 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HHJ44_RS11990 ENOG4108ZZF transport protein (ExbD) HHJ44_RS11995 ENOG4105CWK Biopolymer transport protein, ExbB HHJ44_RS12000 ENOG4105C28 cystathionine HHJ44_RS12005 ENOG4108K81 inner membrane protein YghB HHJ44_RS12010 ENOG4105CF7 AraC family transcriptional regulator HHJ44_RS12015 ENOG4108I6A alcohol dehydrogenase HHJ44_RS12020 ENOG4105CV8 reductase HHJ44_RS12025 ENOG4105ZKC Conserved Protein HHJ44_RS12035 ENOG4105CCT upf0313 protein HHJ44_RS12040 ENOG4107YCY Transcriptional regulator HHJ44_RS12045 ENOG4105DEI Mannitol dehydrogenase HHJ44_RS12050 ENOG4105CPQ Dehydrogenase HHJ44_RS12055 ENOG4105DG4 malate L-lactate dehydrogenase HHJ44_RS12060 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ44_RS12070 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ44_RS12075 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HHJ44_RS12080 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HHJ44_RS12085 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ44_RS12090 ENOG4108J59 Extracellular solute-binding protein, family 5 HHJ44_RS12095 ENOG4105F4I Transcriptional regulator HHJ44_RS12100 ENOG4105H4F exported protein HHJ44_RS12105 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ44_RS12110 ENOG4105DHQ Histidine kinase HHJ44_RS12115 ENOG4107DEU Inner membrane protein YgiZ HHJ44_RS12125 ENOG4105NF4 modulator of drug activity HHJ44_RS12130 ENOG4105VRH Antibiotic biosynthesis monooxygenase HHJ44_RS12135 ENOG4106KNT transcriptional regulator HHJ44_RS12145 ENOG4105EHG Permease protein HHJ44_RS12150 ENOG4105DQ5 transport system permease protein HHJ44_RS12155 ENOG4105E0A ABC, transporter HHJ44_RS12165 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ44_RS12170 ENOG4105IPS esterase HHJ44_RS12175 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HHJ44_RS12180 ENOG4108SX3 cytoplasmic protein HHJ44_RS12185 ENOG41087AY ADP-Ribose pyrophosphatase HHJ44_RS12190 ENOG4105DFG type I secretion outer membrane protein HHJ44_RS12200 ENOG4106032 Glutathionylspermidine synthase HHJ44_RS12205 ENOG4108MR7 Arylsulfotransferase HHJ44_RS12210 ENOG4108N92 Thiol disulfide Interchange Protein HHJ44_RS12220 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HHJ44_RS12235 ENOG4105H8W Fimbrial protein HHJ44_RS12245 ENOG4108TTM chaperone HHJ44_RS12250 ENOG4108MY7 Fimbrial HHJ44_RS12260 ENOG4105W0Z cytoplasmic protein HHJ44_RS12270 ENOG4105PV3 Inner membrane protein yqiJ HHJ44_RS12275 ENOG4107S78 Band 7 protein HHJ44_RS12295 ENOG4105I7R Adenylate cyclase HHJ44_RS12300 ENOG4106MWK domain protein HHJ44_RS12315 ENOG4107ZVW dihydroneopterin aldolase HHJ44_RS12335 ENOG4107GFK fumarate HHJ44_RS12355 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HHJ44_RS12360 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ44_RS12375 ENOG4105Q26 Siderophore-interacting protein HHJ44_RS12380 ENOG4105NTW Transcriptional regulator HHJ44_RS12385 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HHJ44_RS12395 ENOG4108Y51 tRNA-binding protein HHJ44_RS12400 ENOG4105CQ4 Transcriptional regulator HHJ44_RS12405 ENOG4105CNT hydrolase family 2 HHJ44_RS12410 ENOG4105FK9 beta-D-galactosidase beta subunit HHJ44_RS12415 ENOG4105E5D amino acid HHJ44_RS12420 ENOG4107W6W Conserved Protein HHJ44_RS12425 ENOG4107WCA isomerase HHJ44_RS12430 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ44_RS12440 ENOG4108VKG metal-dependent hydrolase HHJ44_RS12445 ENOG4108UB4 uncharacterized protein ygjQ HHJ44_RS12450 ENOG4105EE0 oxidoreductase HHJ44_RS12455 ENOG4105DU1 integral membrane protein, terc HHJ44_RS12465 ENOG4105P66 Membrane HHJ44_RS12470 ENOG4105CTX dehydratase HHJ44_RS12480 ENOG4105DPW Major facilitator superfamily MFS_1 HHJ44_RS12485 ENOG4107YCY Transcriptional regulator HHJ44_RS12490 ENOG4106W5V Membrane HHJ44_RS12495 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HHJ44_RS12500 ENOG4105WAY exported protein HHJ44_RS12505 ENOG4105NE1 Conserved Protein HHJ44_RS12510 ENOG41090KG Inner membrane protein YqjE HHJ44_RS12515 ENOG4105YJD HHJ44_RS12520 ENOG4108VBZ doxx family HHJ44_RS12525 ENOG4105CHF Glutathione S-transferase HHJ44_RS12530 ENOG4105KAF membrAne HHJ44_RS12535 ENOG4105CWB LysR family transcriptional Regulator HHJ44_RS12540 ENOG4108CNN domain protein HHJ44_RS12545 ENOG4106D80 Uncharacterized protein YhaL HHJ44_RS12555 ENOG4105C44 Serine transporter HHJ44_RS12560 ENOG4105EJQ L-serine dehydratase HHJ44_RS12565 ENOG4105KME endoribonuclease L-psp HHJ44_RS12570 ENOG4105C6N Formate acetyltransferase HHJ44_RS12585 ENOG4105C7B Threonine dehydratase HHJ44_RS12590 ENOG410811B TRANSCRIPTIONal HHJ44_RS12605 ENOG4105BZW Glycerate kinase HHJ44_RS12610 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ44_RS12620 ENOG4105DJB Major Facilitator Superfamily HHJ44_RS12625 ENOG4105CTX dehydratase HHJ44_RS12630 ENOG4105E98 transcriptional regulator DeoR family HHJ44_RS12640 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HHJ44_RS12650 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ44_RS12655 ENOG4108YTN IIa component HHJ44_RS12660 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ44_RS12665 ENOG4105E70 isomerase HHJ44_RS12675 ENOG4108UZY PTS System HHJ44_RS12680 ENOG4105ETZ PTS System HHJ44_RS12685 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ44_RS12690 ENOG4106HBN Galactosamine-6-phosphate isomerase HHJ44_RS12695 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HHJ44_RS12700 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) HHJ44_RS12715 ENOG4105W4M Transport-associated protein HHJ44_RS12720 ENOG4107S21 permease HHJ44_RS12725 ENOG4105K4T epimerase HHJ44_RS12730 ENOG4107R7Y intracellular protease Pfpi family HHJ44_RS12745 ENOG4108YYD acetyltransferase HHJ44_RS12765 ENOG4105DEN Luciferase family HHJ44_RS12770 ENOG4105CIC tryptophan-specific transport protein HHJ44_RS12775 ENOG4105C1J atp-dependent rna helicase HHJ44_RS12815 ENOG4105CHV Transcription elongation factor NusA HHJ44_RS12835 ENOG4105DIJ Phosphoethanolamine transferase HHJ44_RS12845 ENOG4105NTZ Preprotein translocase subunit SecG HHJ44_RS12855 ENOG4105EEI dihydropteroate synthase HHJ44_RS12860 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HHJ44_RS12870 ENOG4105HBR Rna-binding protein HHJ44_RS12875 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HHJ44_RS12880 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HHJ44_RS12890 ENOG4105QYV Membrane HHJ44_RS12905 ENOG4105EAH synthase HHJ44_RS12910 ENOG4105HVQ Regulatory factor of maltose metabolism HHJ44_RS12920 ENOG4105VFK BolA family HHJ44_RS12925 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HHJ44_RS12930 ENOG4105E3I toluene tolerance HHJ44_RS12935 ENOG4107PE3 Mammalian cell entry related domain protein HHJ44_RS12940 ENOG4105CY3 ABC transporter, permease HHJ44_RS12945 ENOG4105DHJ ABC, transporter HHJ44_RS12950 ENOG4105FEU K -dependent Na -Ca exchanger HHJ44_RS12955 ENOG4105C2X Arabinose 5-phosphate isomerase HHJ44_RS12965 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HHJ44_RS12970 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HHJ44_RS12975 ENOG4108IUZ ABC transporter HHJ44_RS12980 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ44_RS12985 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HHJ44_RS12990 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HHJ44_RS13000 ENOG41080Z8 PHOSPHOCARRIER protein HHJ44_RS13005 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HHJ44_RS13015 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HHJ44_RS13020 ENOG4105BZU Histidine kinase HHJ44_RS13025 ENOG4105N5T Radical SAM Protein HHJ44_RS13030 ENOG4105CBC glutamate synthase HHJ44_RS13035 ENOG4105BZ8 glutamate synthase HHJ44_RS13040 ENOG4108R66 Conserved Protein HHJ44_RS13070 ENOG4105KB2 stringent starvation protein b HHJ44_RS13075 ENOG4107MKT Stringent starvation protein a HHJ44_RS13090 ENOG4105D6Z AFG1 family ATPase HHJ44_RS13095 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HHJ44_RS13100 ENOG4105C0H protease HHJ44_RS13105 ENOG4105C0H protease HHJ44_RS13120 ENOG4105RID UPF0379 protein yhcN HHJ44_RS13125 ENOG4105UNR (Barnase) inhibitor HHJ44_RS13140 ENOG4105ZQC membrane protein AaeX HHJ44_RS13145 ENOG4105CR8 Transcriptional regulator HHJ44_RS13150 ENOG4105D1U peptidase U62 modulator of DNA gyrase HHJ44_RS13155 ENOG4105QD6 exported protein HHJ44_RS13160 ENOG4105C03 ribonuclease HHJ44_RS13165 ENOG4108Z03 MAF-like protein HHJ44_RS13170 ENOG4105VQ7 Rod shape-determining protein MreD HHJ44_RS13175 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HHJ44_RS13185 ENOG41062P1 Diguanylate cyclase phosphodiesterase HHJ44_RS13190 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HHJ44_RS13200 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HHJ44_RS13205 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HHJ44_RS13215 ENOG4107UEK pfkb domain protein HHJ44_RS13220 ENOG4105CNN ABC, transporter HHJ44_RS13225 ENOG4105C2J ABC transporter HHJ44_RS13230 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ44_RS13235 ENOG4105D2N Aldolase HHJ44_RS13240 ENOG4105E98 transcriptional regulator DeoR family HHJ44_RS13245 ENOG4107UEK pfkb domain protein HHJ44_RS13250 ENOG4105RG0 Membrane HHJ44_RS13255 ENOG4108IA2 Sodium pantothenate symporter HHJ44_RS13265 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ44_RS13275 ENOG4105CEC DNA methylase N-4 N-6 HHJ44_RS13280 ENOG41061ME transport protein HHJ44_RS13285 ENOG4108XG4 DNA-binding transcriptional regulator HHJ44_RS13290 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ44_RS13295 ENOG4105BZS acriflavin resistance protein HHJ44_RS13300 ENOG4105XCM membrane LIPOPROTEIN HHJ44_RS13310 ENOG4105EZ7 amino acid ABC transporter HHJ44_RS13315 ENOG4105DRP amino acid AbC transporter HHJ44_RS13320 ENOG4105CDA abc transporter atp-binding protein HHJ44_RS13355 ENOG4108Z0R Transferase HHJ44_RS13360 ENOG4105SG3 Protein of unknown function (DUF1488) HHJ44_RS13375 ENOG4108WI1 Dna topoisomerase HHJ44_RS13385 ENOG4105C79 DNA protecting protein DprA HHJ44_RS13405 ENOG4105C1A potassium transporter peripheral membrane HHJ44_RS13415 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HHJ44_RS13420 ENOG4105W1Y Transcriptional regulator HHJ44_RS13425 ENOG4105VTS DnaJ-like, subfamily C HHJ44_RS13455 ENOG41067V7 50S ribosomal protein L36 HHJ44_RS13460 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HHJ44_RS13550 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HHJ44_RS13570 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication HHJ44_RS13575 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression HHJ44_RS13580 ENOG4107KSE General secretion pathway protein C HHJ44_RS13585 ENOG4105GVR general secretion pathway protein D HHJ44_RS13590 ENOG4107QHF type ii secretion system protein e HHJ44_RS13595 ENOG4105D7Q type ii secretion system HHJ44_RS13600 ENOG4108VAU general secretion pathway protein G HHJ44_RS13605 ENOG41069X0 general secretion pathway protein h HHJ44_RS13620 ENOG4105R04 type II secretion system protein K HHJ44_RS13625 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) HHJ44_RS13635 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) HHJ44_RS13640 ENOG4108UQY Iron-storage protein HHJ44_RS13645 ENOG4105W53 bacterioferritin-associated ferredoxin HHJ44_RS13650 ENOG4108NNZ chitinase HHJ44_RS13690 ENOG4105WWK YheO domain protein HHJ44_RS13695 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ44_RS13705 ENOG4108YZY peptidylprolyl cis-trans isomerase HHJ44_RS13710 ENOG4105VKU nucleicacid-binding protein HHJ44_RS13725 ENOG4105C5H ABC transporter HHJ44_RS13730 ENOG4105DNZ Alpha Beta Hydrolase HHJ44_RS13740 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HHJ44_RS13745 ENOG4108UKZ OsmC family HHJ44_RS13755 ENOG410613R integral membrane protein, YccS YhfK family HHJ44_RS13760 ENOG4105C8Y Acetylornithine aminotransferase HHJ44_RS13765 ENOG4105DDQ anthranilate synthase HHJ44_RS13770 ENOG4105MZU cell filamentation protein HHJ44_RS13780 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ44_RS13790 ENOG4107QZF nitrite reductase NADPH large subunit HHJ44_RS13795 ENOG4105WZK nitrite reductase NADPH small subunit HHJ44_RS13800 ENOG4107V9H nitrite transporter HHJ44_RS13810 ENOG4105VYH HHJ44_RS13815 ENOG4106PKC pyridoxal phosphate binding HHJ44_RS13820 ENOG4106M0N transport system permease protein HHJ44_RS13825 ENOG4105MUZ Protein of unknown function DUF2620 HHJ44_RS13830 ENOG41080QX K07048 phosphotriesterase-related protein HHJ44_RS13835 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HHJ44_RS13840 ENOG4108626 Racemase HHJ44_RS13845 ENOG4105RMW regulation of transcription, DNA-dependent HHJ44_RS13850 ENOG4108M21 HHJ44_RS13855 ENOG4105C31 Tryptophanyl-tRNA synthetase HHJ44_RS13860 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HHJ44_RS13865 ENOG4105DJV ribulose-phosphate 3-epimerase HHJ44_RS13870 ENOG4105DFE Dna adenine methylase HHJ44_RS13875 ENOG4105EGB membrane protein DamX HHJ44_RS13890 ENOG4105E4G Type IV pilus HHJ44_RS13895 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HHJ44_RS13900 ENOG4105XPX DNA utilization protein HofO HHJ44_RS13905 ENOG41065NF Fimbrial assembly family protein HHJ44_RS13910 ENOG4108U1Q Pilus assembly protein HHJ44_RS13915 ENOG4108JQC penicillin-binding protein 1A HHJ44_RS13920 ENOG4107RK2 ADP-ribose diphosphatase NudE HHJ44_RS13925 ENOG4105DQY intracellular growth attenuator HHJ44_RS13930 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HHJ44_RS13935 ENOG4105VEJ Heat shock protein HHJ44_RS13945 ENOG4108MAJ Membrane HHJ44_RS13955 ENOG4105E0F Histidine kinase HHJ44_RS13965 ENOG4108RRZ Transcription elongation factor GreB HHJ44_RS13970 ENOG4105BZM domain protein HHJ44_RS13975 ENOG4105XFK Ferrous iron transport protein A HHJ44_RS13980 ENOG4105CE1 Ferrous iron transport protein b HHJ44_RS13990 ENOG4105DNE Transposase HHJ44_RS14000 ENOG4105MJ2 Competence protein HHJ44_RS14010 ENOG4105C6Z Gluconate HHJ44_RS14015 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HHJ44_RS14020 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ44_RS14035 ENOG4105E0Y RtcB Protein HHJ44_RS14040 ENOG4105CYB regulatoR HHJ44_RS14045 ENOG4105E98 transcriptional regulator DeoR family HHJ44_RS14060 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HHJ44_RS14080 ENOG4105MHR Fimbrial protein HHJ44_RS14085 ENOG4108AF8 Chaperone HHJ44_RS14090 ENOG4108RQP Major type 1 subunit fimbrin HHJ44_RS14100 ENOG4105CW0 outer membrane usher protein HHJ44_RS14105 ENOG4108NAE Fimbrial chaperone protein HHJ44_RS14115 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HHJ44_RS14140 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HHJ44_RS14145 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HHJ44_RS14150 ENOG4105C6Z Gluconate HHJ44_RS14155 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HHJ44_RS14160 ENOG4105DIQ Transcriptional regulator HHJ44_RS14165 ENOG4105C2I pirin domain protein HHJ44_RS14170 ENOG4105D9R oxidoreductase HHJ44_RS14175 ENOG4105WCN acetyltransferase HHJ44_RS14180 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ44_RS14185 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ44_RS14200 ENOG4106FA4 HHJ44_RS14205 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HHJ44_RS14210 ENOG4105WC8 Conserved Protein HHJ44_RS14215 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HHJ44_RS14235 ENOG4105BZ7 extracellular solute-binding protein family 1 HHJ44_RS14240 ENOG4108IV0 ABC, transporter HHJ44_RS14245 ENOG4105C0Z ABC transporter HHJ44_RS14250 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HHJ44_RS14255 ENOG4105C32 Amino acid ABC transporter (Permease) HHJ44_RS14260 ENOG4105CP9 extracellular ligand-binding receptor HHJ44_RS14265 ENOG4105U59 -acetyltransferase HHJ44_RS14270 ENOG4105CP9 extracellular ligand-binding receptor HHJ44_RS14295 ENOG4108JQ1 Dehydrogenase HHJ44_RS14300 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HHJ44_RS14305 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HHJ44_RS14310 ENOG4105CRP Part of the ABC transporter FtsEX involved in HHJ44_RS14315 ENOG4105CAK Cell division ATP-binding protein ftsE HHJ44_RS14320 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HHJ44_RS14325 ENOG4106H78 methyltransferase HHJ44_RS14330 ENOG4105MG3 Membrane HHJ44_RS14340 ENOG4107FS9 Membrane HHJ44_RS14355 ENOG4105EX9 Membrane HHJ44_RS14360 ENOG4108W1V Lipoprotein HHJ44_RS14365 ENOG4105F9N Major Facilitator Superfamily HHJ44_RS14370 ENOG4105DSF transport protein HHJ44_RS14375 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HHJ44_RS14380 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HHJ44_RS14385 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ44_RS14390 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ44_RS14395 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HHJ44_RS14400 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HHJ44_RS14420 ENOG41090UW PTS System HHJ44_RS14425 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ44_RS14440 ENOG4105D2N Aldolase HHJ44_RS14445 ENOG4105CMI transporter HHJ44_RS14450 ENOG4105CJ1 ABC, transporter HHJ44_RS14455 ENOG4105D0S secretion protein (HlyD HHJ44_RS14460 ENOG4107UNS conserved inner membrane protein HHJ44_RS14465 ENOG4105CBX hi0933 family HHJ44_RS14470 ENOG4105CJ3 phosphate transporter HHJ44_RS14485 ENOG4105DUX Transporter HHJ44_RS14495 ENOG4105DGW oligopeptidase A HHJ44_RS14500 ENOG4105D6S protein involved in catabolism of external DNA HHJ44_RS14505 ENOG4105DC8 reductase HHJ44_RS14515 ENOG4105K89 arsenate reductase HHJ44_RS14525 ENOG4105Y4Z Outer Membrane Lipoprotein HHJ44_RS14535 ENOG4106QJH hemin transport protein HHJ44_RS14540 ENOG4107ENK receptor HHJ44_RS14550 ENOG4105D4P Coproporphyrinogen iii oxidase HHJ44_RS14555 ENOG41090JE Utilization Protein HHJ44_RS14565 ENOG4105EHG Permease protein HHJ44_RS14575 ENOG4105KT7 mgtC SapB transporter HHJ44_RS14580 ENOG4105XXV Acid-resistance protein HHJ44_RS14585 ENOG41060V2 Acid-resistance protein HHJ44_RS14590 ENOG4108YK4 Acid-resistance membrane protein HHJ44_RS14595 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HHJ44_RS14605 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ44_RS14610 ENOG4105BZS acriflavin resistance protein HHJ44_RS14615 ENOG4105D3F AraC Family Transcriptional Regulator HHJ44_RS14620 ENOG4108NKV transcriptional regulator HHJ44_RS14625 ENOG4105CVK Glutamate decarboxylase HHJ44_RS14630 ENOG4105CA0 peroxidase HHJ44_RS14640 ENOG4106S2D Transcriptional regulator HHJ44_RS14645 ENOG4105CBN LysR family transcriptional regulator HHJ44_RS14650 ENOG4107H3J ribonuclease HHJ44_RS14655 ENOG4105CSH Transporter HHJ44_RS14660 ENOG41066T0 asmA family HHJ44_RS14665 ENOG4105CMB EAL domain-containing protein HHJ44_RS14670 ENOG4107SS6 2-dehydro-3-deoxygluconokinase HHJ44_RS14675 ENOG4105CS0 peptidase HHJ44_RS14685 ENOG4105BZU Histidine kinase HHJ44_RS14690 ENOG4105EJG cellulose synthase HHJ44_RS14695 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HHJ44_RS14700 ENOG4107EEX Cellulose synthase regulator protein HHJ44_RS14705 ENOG4107QZ7 Cellulose synthase catalytic subunit HHJ44_RS14730 ENOG4105C44 Serine transporter HHJ44_RS14735 ENOG4108JQ7 (ABC) transporter HHJ44_RS14740 ENOG4105C3U ABC transporter HHJ44_RS14745 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ44_RS14750 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ44_RS14755 ENOG4105DEF Extracellular solute-binding protein, family 5 HHJ44_RS14765 ENOG4105DIJ Phosphoethanolamine transferase HHJ44_RS14770 ENOG4105FCD Major Facilitator HHJ44_RS14775 ENOG4105EAX Putative lipase HHJ44_RS14780 ENOG4108R3E Dna-3-methyladenine glycosylase i HHJ44_RS14785 ENOG4105HNP -acetyltransferase HHJ44_RS14790 ENOG4107QY8 reductase HHJ44_RS14795 ENOG4108ZG0 Ompa motb domain protein HHJ44_RS14805 ENOG4106JH6 (LipO)protein HHJ44_RS14810 ENOG4105MVF Transcriptional regulator HHJ44_RS14820 ENOG41060TC Hok gef cell toxic protein HHJ44_RS14840 ENOG4105MEV Acyl-transferase HHJ44_RS14845 ENOG4108Z12 YiaAB two helix domain-containing protein HHJ44_RS14850 ENOG410688U Inner membrane protein yiaB HHJ44_RS14855 ENOG4105CMG Carbohydrate kinase HHJ44_RS14865 ENOG4105DFW ABC transporter HHJ44_RS14875 ENOG4108HWW ABC transporter HHJ44_RS14880 ENOG4105T16 Transcriptional regulator (AraC family) HHJ44_RS14885 ENOG4108UR8 BAX protein HHJ44_RS14890 ENOG4107T9C Alpha amylase catalytic region HHJ44_RS14895 ENOG4105JKW Valine--pyruvate aminotransferase HHJ44_RS14900 ENOG4108XIB electron transport protein ysaA HHJ44_RS14905 ENOG4105J4Q Transcriptional regulator HHJ44_RS14915 ENOG4108R66 Conserved Protein HHJ44_RS14920 ENOG4108M5W HHJ44_RS14925 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HHJ44_RS14930 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HHJ44_RS14935 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HHJ44_RS14940 ENOG4105CMG Carbohydrate kinase HHJ44_RS14945 ENOG4105H6Q decarboxylase HHJ44_RS14950 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HHJ44_RS14955 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ44_RS14960 ENOG4105C26 Dehydrogenase HHJ44_RS14970 ENOG4105C0A alcohol dehydrogenase HHJ44_RS14975 ENOG4105EM7 Selenocysteine-specific translation elongation factor HHJ44_RS14985 ENOG4108U78 Glutathione S-transferase HHJ44_RS14990 ENOG4105EFX secretion protein, HlyD family HHJ44_RS14995 ENOG4105FP6 Protein of unknown function (DUF3302) HHJ44_RS15000 ENOG4105CTS PTS system mannitol-specific HHJ44_RS15010 ENOG4105E61 Mannitol repressor protein HHJ44_RS15015 ENOG41060ND LF82 chromosome, complete sequence HHJ44_RS15020 ENOG4108YYI Protein of unknown function (DUF2810) HHJ44_RS15025 ENOG4108WY4 inner membrane lipoprotein HHJ44_RS15035 ENOG4105DAA L-lactate HHJ44_RS15040 ENOG41073TP transcriptional regulator HHJ44_RS15050 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HHJ44_RS15055 ENOG4105D7W serine acetyltransferase HHJ44_RS15070 ENOG4105VW4 glutaredoxin 3 HHJ44_RS15075 ENOG4107YZP Rhodanese domain protein HHJ44_RS15085 ENOG41063SB peptidase HHJ44_RS15090 ENOG4105PXI polysaccharide deacetylase HHJ44_RS15095 ENOG4105K64 Glycosyl transferase, family 2 HHJ44_RS15105 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HHJ44_RS15115 ENOG4105XA0 heptosyltransferase ii HHJ44_RS15120 ENOG4105D16 lipopolysaccharide heptosyltransferase i HHJ44_RS15125 ENOG41068PG O-Antigen polymerase HHJ44_RS15130 ENOG4105K64 Glycosyl transferase, family 2 HHJ44_RS15135 ENOG4105X1N Glycosyl transferase family 8 HHJ44_RS15150 ENOG4106AH0 Glycosyl Transferase HHJ44_RS15155 ENOG4107543 (lipo)polysaccharide HHJ44_RS15160 ENOG4107RJ7 Glycosyl transferase (Group 1 HHJ44_RS15165 ENOG4105DKP glycosyl transferase, family 9 HHJ44_RS15170 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HHJ44_RS15190 ENOG4105KDC 50s ribosomal protein l28 HHJ44_RS15200 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HHJ44_RS15225 ENOG4105DSJ YicC domain protein HHJ44_RS15340 ENOG4105F5P DNA-damage-inducible protein d HHJ44_RS15345 ENOG4105EN6 Membrane HHJ44_RS15355 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HHJ44_RS15365 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HHJ44_RS15370 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HHJ44_RS15375 ENOG4105CB5 ATP-dependent DNA helicase recG HHJ44_RS15380 ENOG4105D6U Sodium Glutamate Symporter HHJ44_RS15385 ENOG4105C2W permease HHJ44_RS15390 ENOG4105JV1 AsmA family HHJ44_RS15400 ENOG4105DKQ ROK family HHJ44_RS15410 ENOG4105D2N Aldolase HHJ44_RS15415 ENOG4105DM4 PTS System HHJ44_RS15420 ENOG4108YRF PTS System HHJ44_RS15425 ENOG4105DM4 PTS System HHJ44_RS15430 ENOG4105ETD TRANSCRIPTIONal HHJ44_RS15435 ENOG4105CJQ hydrolase, family 31 HHJ44_RS15440 ENOG4105CT4 transporter HHJ44_RS15460 ENOG4108UZ3 Transporter HHJ44_RS15465 ENOG4105D01 (LipO)protein HHJ44_RS15470 ENOG4105T8A Uncharacterized protein YicS HHJ44_RS15480 ENOG4108SAJ Protein of unknown function (DUF1198) HHJ44_RS15485 ENOG4105C7N Xanthine uracil vitamin C permease HHJ44_RS15495 ENOG4105CXY transporter HHJ44_RS15500 ENOG4105CXY transporter HHJ44_RS15505 ENOG4105BZU Histidine kinase HHJ44_RS15510 ENOG4108KX4 response regulator HHJ44_RS15515 ENOG4105M71 acetolactate synthase 1 regulatory subunit HHJ44_RS15520 ENOG4105C7K acetolactate synthase HHJ44_RS15530 ENOG4105E5M Multidrug resistance protein D HHJ44_RS15535 ENOG4105J13 transcriptional regulator HHJ44_RS15540 ENOG4105JP4 Inner membrane protein yidG HHJ44_RS15545 ENOG4105VG5 Membrane HHJ44_RS15555 ENOG4107RUZ Sss sodium solute transporter superfamily HHJ44_RS15560 ENOG4108AHD Transcriptional regulator HHJ44_RS15580 ENOG4105R2A (LipO)protein HHJ44_RS15585 ENOG4105D99 atp gtp-binding protein HHJ44_RS15595 ENOG4105DJB Major Facilitator Superfamily HHJ44_RS15605 ENOG4108RTU Aldolase HHJ44_RS15610 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HHJ44_RS15615 ENOG4105EMF GntR family transcriptional regulator HHJ44_RS15620 ENOG410657R replicase EC 2.7 HHJ44_RS15625 ENOG410667J hydrolase HHJ44_RS15630 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HHJ44_RS15635 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HHJ44_RS15645 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HHJ44_RS15660 ENOG4105VG0 50S ribosomal protein l34 HHJ44_RS15695 ENOG4108P6C Tryptophan transporter of low affinity HHJ44_RS15705 ENOG4105G2Y Transcriptional regulator HHJ44_RS15710 ENOG4105E8Q phosphopantetheinyl transferase HHJ44_RS15715 ENOG4108YYH Nadph-dependent fmn reductase HHJ44_RS15720 ENOG4105C7N Xanthine uracil vitamin C permease HHJ44_RS15735 ENOG4107VKM 6-phosphogluconolactonase HHJ44_RS15740 ENOG4105DYC esterase HHJ44_RS15750 ENOG4105CS2 ec 3.2.1.21 HHJ44_RS15755 ENOG4105C5Y PTS System HHJ44_RS15760 ENOG4105CID antiterminator HHJ44_RS15765 ENOG4108UTW Plays a role in the regulation of phosphate uptake HHJ44_RS15770 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HHJ44_RS15775 ENOG4105E2Z phosphate ABC transporter (Permease HHJ44_RS15780 ENOG4105C8U phosphate abc transporter HHJ44_RS15785 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HHJ44_RS15790 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HHJ44_RS15840 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HHJ44_RS15855 ENOG4105QTB Flavodoxin HHJ44_RS15860 ENOG4108VVK transcriptional Regulator, AsnC HHJ44_RS15895 ENOG4105CNN ABC, transporter HHJ44_RS15900 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ44_RS15905 ENOG4108RVA ribokinase HHJ44_RS15910 ENOG4105ETE Transcriptional regulator (LacI family HHJ44_RS15915 ENOG4105C0R drug resistance transporter emrb qaca subfamily HHJ44_RS15920 ENOG4107EJG GntR family transcriptional regulator HHJ44_RS15960 ENOG4108WFC UPF0438 protein yifE HHJ44_RS15965 ENOG4105C0P Mg chelatase subunit ChlI HHJ44_RS15985 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HHJ44_RS15990 ENOG4105CM2 brancheD-chain amino acid aminotransferase HHJ44_RS16000 ENOG4105C7B Threonine dehydratase HHJ44_RS16005 ENOG4105EMY transcriptional regulator HHJ44_RS16015 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HHJ44_RS16020 ENOG4105C4R Atp-dependent dna helicase HHJ44_RS16045 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HHJ44_RS16050 ENOG4105ESV Glycosyl transferase, family 4 HHJ44_RS16055 ENOG4105SFE lipopolysaccharide biosynthesis protein HHJ44_RS16060 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HHJ44_RS16065 ENOG4107QQG Dehydrogenase HHJ44_RS16070 ENOG4105C1B dTDP-glucose 4-6-dehydratase HHJ44_RS16075 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HHJ44_RS16080 ENOG4108WJ1 acetyltransferase HHJ44_RS16085 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HHJ44_RS16090 ENOG4105EGZ biosynthesis protein HHJ44_RS16110 ENOG4105C85 amino acid HHJ44_RS16135 ENOG4105C4X radical SAM domain protein HHJ44_RS16140 ENOG4105ENH Sulfatase HHJ44_RS16145 ENOG410601J HemY protein HHJ44_RS16150 ENOG4105ECF c-methyltransferase HHJ44_RS16155 ENOG41076E6 Uroporphyrinogen-III Synthase HHJ44_RS16165 ENOG4107T0K Adenylate cyclase HHJ44_RS16185 ENOG4105S7Z (LipO)protein HHJ44_RS16195 ENOG4105CT0 Protein of unknown function, DUF484 HHJ44_RS16205 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HHJ44_RS16210 ENOG4105C4R Atp-dependent dna helicase HHJ44_RS16215 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase HHJ44_RS16220 ENOG4108T58 Mg2 transport protein CorA HHJ44_RS16225 ENOG4107QUT magnesium and cobalt transport protein CorA HHJ44_RS16240 ENOG4105FR1 rard protein HHJ44_RS16245 ENOG4108VUY thioesterase Superfamily protein HHJ44_RS16250 ENOG4105HDD phospholipase HHJ44_RS16255 ENOG4105C9U ATP-dependent DNA helicase RecQ HHJ44_RS16260 ENOG4105CCF Lysine exporter protein (Lyse ygga) HHJ44_RS16265 ENOG410829K Lysine exporter protein (Lyse ygga) HHJ44_RS16270 ENOG4108EUD Lysophospholipase HHJ44_RS16275 ENOG4105DQF Hydrolase HHJ44_RS16280 ENOG4105EMK carboxylate amino acid amine transporter HHJ44_RS16285 ENOG4105DZ2 Transcriptional regulator HHJ44_RS16305 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ44_RS16320 ENOG4105CV1 Transketolase (EC 2.2.1.1) HHJ44_RS16325 ENOG4106KNT transcriptional regulator HHJ44_RS16330 ENOG4105F52 Transcriptional regulator HHJ44_RS16335 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HHJ44_RS16345 ENOG4105C5B carbamate kinase HHJ44_RS16350 ENOG4107REC cytoplasmic protein HHJ44_RS16355 ENOG4107R1Q Membrane protein FdrA HHJ44_RS16365 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) HHJ44_RS16370 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HHJ44_RS16375 ENOG4108I5U Uridine phosphorylase HHJ44_RS16390 ENOG4105JN3 extra-cytoplasmic solute receptor family protein HHJ44_RS16395 ENOG4108RTU Aldolase HHJ44_RS16400 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HHJ44_RS16405 ENOG4107HP6 Transcriptional regulator HHJ44_RS16410 ENOG4105CGY Dna recombination protein HHJ44_RS16420 ENOG4105JC1 sterol-binding domain protein HHJ44_RS16430 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HHJ44_RS16435 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HHJ44_RS16440 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HHJ44_RS16450 ENOG4105MDZ Transcriptional activator rfaH HHJ44_RS16455 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HHJ44_RS16460 ENOG4108EX3 reductase HHJ44_RS16480 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HHJ44_RS16485 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HHJ44_RS16490 ENOG4108RR8 protoporphyrinogen oxidase HHJ44_RS16520 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HHJ44_RS16525 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HHJ44_RS16530 ENOG4105PC1 Conserved Protein HHJ44_RS16535 ENOG4105E27 serine threonine protein kinase HHJ44_RS16540 ENOG4108Z33 Thiol disulfide Interchange Protein HHJ44_RS16550 ENOG4106HNH Acyl-transferase HHJ44_RS16555 ENOG4105C2M dna polymerase I HHJ44_RS16570 ENOG4105D4P Coproporphyrinogen iii oxidase HHJ44_RS16575 ENOG4106FIY HHJ44_RS16580 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ44_RS16585 ENOG4105CUX Signal transduction histidine kinase HHJ44_RS16590 ENOG4105C5F glutamine synthetase HHJ44_RS16595 ENOG4105CI3 gtp-binding protein typa HHJ44_RS16600 ENOG4105E98 transcriptional regulator DeoR family HHJ44_RS16605 ENOG4108MGF sugar kinase HHJ44_RS16610 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ44_RS16615 ENOG4105D2M Aldolase HHJ44_RS16620 ENOG4105CPQ Dehydrogenase HHJ44_RS16630 ENOG4105CSH Transporter HHJ44_RS16640 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HHJ44_RS16655 ENOG4105SUU thioesterase domain HHJ44_RS16665 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system HHJ44_RS16690 ENOG4108MG3 formate dehydrogenase HHJ44_RS16695 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ44_RS16755 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HHJ44_RS16765 ENOG4108RPX mosc domain containing protein HHJ44_RS16770 ENOG4105E0F Histidine kinase HHJ44_RS16775 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ44_RS16780 ENOG4105FMW periplasmic HHJ44_RS16795 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HHJ44_RS16810 ENOG4105EBK exported protein HHJ44_RS16815 ENOG4108VTS Membrane HHJ44_RS16820 ENOG41065TG regulatoR HHJ44_RS16830 ENOG4105DP0 ferredoxin-NADP reductase HHJ44_RS16835 ENOG4105CBT Fructose-1,6-bisphosphatase HHJ44_RS16845 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HHJ44_RS16860 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HHJ44_RS16875 ENOG41063M6 Cell Division Protein HHJ44_RS16880 ENOG4105ETE Transcriptional regulator (LacI family HHJ44_RS16885 ENOG4105C25 Primosomal protein n' HHJ44_RS16895 ENOG4107S01 Repressor protein MetJ HHJ44_RS16905 ENOG4105C28 cystathionine HHJ44_RS16910 ENOG4105CFH Aspartokinase HHJ44_RS16915 ENOG4105DRB nucleoside-specific channel-forming protein HHJ44_RS16920 ENOG4105CGH 5'-nucleotidase HHJ44_RS16925 ENOG4105CGH 5'-nucleotidase HHJ44_RS16935 ENOG4105CGH 5'-nucleotidase HHJ44_RS16940 ENOG4105SYT Methylenetetrahydrofolate reductase HHJ44_RS16950 ENOG4108Q5Y Membrane HHJ44_RS16955 ENOG4108XC3 NADH ubiquinone oxidoreductase HHJ44_RS16960 ENOG4105DCT glycerol dehydrogenase HHJ44_RS16965 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ44_RS16970 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HHJ44_RS16975 ENOG4105DM4 PTS System HHJ44_RS16980 ENOG4108YRF PTS System HHJ44_RS16990 ENOG4108AHH pyruvate formate lyase II activase HHJ44_RS16995 ENOG4108XCZ PTS System HHJ44_RS17000 ENOG4106R3P AraC family transcriptional regulator HHJ44_RS17005 ENOG4105DIJ Phosphoethanolamine transferase HHJ44_RS17020 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HHJ44_RS17035 ENOG4105CXK mandelate racemase muconate lactonizing HHJ44_RS17040 ENOG4108I5G Major Facilitator superfamily HHJ44_RS17045 ENOG4105C5Q Transcriptional regulator HHJ44_RS17055 ENOG4105CH2 amidohydrolase HHJ44_RS17070 ENOG4108Y73 Membrane HHJ44_RS17110 ENOG4105D4A Cell wall formation (By similarity) HHJ44_RS17115 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HHJ44_RS17150 ENOG4105PM1 preprotein translocase subunit SecE HHJ44_RS17155 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HHJ44_RS17190 ENOG4105D41 biosynthesis protein thiH HHJ44_RS17200 ENOG4105WHD thiamine biosynthesis protein ThiS HHJ44_RS17205 ENOG4105D06 uba thif-type nad fad binding protein HHJ44_RS17240 ENOG4105R2J Conserved Protein HHJ44_RS17250 ENOG4108T8B Protein of unknown function (DUF1481) HHJ44_RS17255 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HHJ44_RS17260 ENOG4105BZU Histidine kinase HHJ44_RS17265 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ44_RS17270 ENOG4105C12 Phosphoribosylglycinamide synthetase HHJ44_RS17300 ENOG41062WK cellular response to acidity HHJ44_RS17305 ENOG4105K5X acetyltransferase HHJ44_RS17315 ENOG4107QP3 malate synthase g HHJ44_RS17320 ENOG4108I9X Isocitrate lyase HHJ44_RS17330 ENOG41069M3 Transcriptional regulator HHJ44_RS17335 ENOG4105C3R Methionine synthase HHJ44_RS17350 ENOG4105EAM Na Pi-cotransporter HHJ44_RS17360 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HHJ44_RS17365 ENOG4105F3R pts system mannose fructose sorbose family iid HHJ44_RS17370 ENOG4105ETZ PTS System HHJ44_RS17375 ENOG4105KPI PTS system sorbose subfamily IIB component HHJ44_RS17380 ENOG4108XCU pts system HHJ44_RS17385 ENOG4105CHR reductase HHJ44_RS17390 ENOG4105DKT Transcriptional regulator HHJ44_RS17395 ENOG4105FE9 pseudouridine synthase HHJ44_RS17400 ENOG4108ZR5 Conserved Protein HHJ44_RS17405 ENOG4105CFH Aspartokinase HHJ44_RS17420 ENOG4108MDC (LipO)protein HHJ44_RS17425 ENOG4108Q9C Periplasmic Protein HHJ44_RS17430 ENOG4105E3R (LipO)protein HHJ44_RS17445 ENOG4105EG2 ABC transporter, permease HHJ44_RS17450 ENOG4105D56 permease protein HHJ44_RS17455 ENOG4107FKK extracellular solute-binding protein family 1 HHJ44_RS17460 ENOG4108IJ9 (ABC) transporter HHJ44_RS17470 ENOG4107W52 maltose operon periplasmic protein HHJ44_RS17490 ENOG41080IJ Diacylglycerol kinase HHJ44_RS17500 ENOG4107R73 Mate efflux family protein HHJ44_RS17505 ENOG4105VDW Csbd family HHJ44_RS17510 ENOG4105MYN Zinc uptake regulation protein HHJ44_RS17515 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HHJ44_RS17520 ENOG4105P4Z Phage shock protein G HHJ44_RS17525 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HHJ44_RS17530 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ44_RS17540 ENOG4106YT9 Enoyl-CoA hydratase HHJ44_RS17545 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ44_RS17550 ENOG4105ETE Transcriptional regulator (LacI family HHJ44_RS17555 ENOG4105CDU Replicative dna helicase HHJ44_RS17560 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HHJ44_RS17565 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HHJ44_RS17570 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HHJ44_RS17575 ENOG4105CGF Aromatic amino acid aminotransferase HHJ44_RS17580 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HHJ44_RS17585 ENOG4105C7S Dehydrogenase HHJ44_RS17590 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ44_RS17595 ENOG4105CMV Succinyl-CoA synthetase subunit beta HHJ44_RS17600 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HHJ44_RS17605 ENOG4107QPK )-transporter HHJ44_RS17610 ENOG4105DG4 malate L-lactate dehydrogenase HHJ44_RS17615 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HHJ44_RS17620 ENOG4105CQZ Histidine kinase HHJ44_RS17625 ENOG4105F0S class B acid phosphatase HHJ44_RS17630 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HHJ44_RS17635 ENOG4105MSB protein, conserved in bacteria HHJ44_RS17640 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HHJ44_RS17645 ENOG4108UUM single-stranded DNA-binding protein HHJ44_RS17650 ENOG4105PMV Membrane HHJ44_RS17655 ENOG4108M8H domain protein HHJ44_RS17660 ENOG4108W3Q Transcriptional regulator HHJ44_RS17665 ENOG4108Z4X TRANSCRIPTIONal HHJ44_RS17670 ENOG4105C7N Xanthine uracil vitamin C permease HHJ44_RS17675 ENOG4105EEQ Na H antiporter HHJ44_RS17680 ENOG4105CMU LysR family (Transcriptional regulator HHJ44_RS17690 ENOG41067MG lrgb family HHJ44_RS17700 ENOG41062QD Membrane HHJ44_RS17705 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ44_RS17715 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HHJ44_RS17720 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HHJ44_RS17725 ENOG4105DVI reductase, NrfD HHJ44_RS17730 ENOG4108QKW cytochrome c-type biogenesis protein HHJ44_RS17740 ENOG4108W0S formate-dependent nitrite reductase complex HHJ44_RS17745 ENOG4105CK2 sodium dicarboxylate symporter HHJ44_RS17750 ENOG41082ND Uncharacterized protein yjcO HHJ44_RS17755 ENOG4108JQ7 (ABC) transporter HHJ44_RS17760 ENOG4105C3U ABC transporter HHJ44_RS17765 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HHJ44_RS17770 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HHJ44_RS17785 ENOG4105ETP RND efflux system, outer membrane lipoprotein HHJ44_RS17790 ENOG4108MI0 Resistance protein HHJ44_RS17795 ENOG4105J12 Multidrug resistance protein mdtN HHJ44_RS17805 ENOG4105EUZ Beta-lactamase domain protein HHJ44_RS17810 ENOG4107TFG D-allose kinase HHJ44_RS17815 ENOG4105UP7 3-epimerase HHJ44_RS17825 ENOG4105C2J ABC transporter HHJ44_RS17830 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ44_RS17835 ENOG4105NYY transcriptional regulator, RpiR HHJ44_RS17840 ENOG4108YZG isomerase HHJ44_RS17850 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HHJ44_RS17855 ENOG410849A acetyltransferase, (GNAT) family HHJ44_RS17865 ENOG4105FD8 phosphonate metabolism protein PhnM HHJ44_RS17870 ENOG4105HRV phosphonate c-p lyase system protein phnl HHJ44_RS17875 ENOG4105ENV phosphonate C-P lyase system protein PhnK HHJ44_RS17880 ENOG4105FT8 Phosphonate metabolism HHJ44_RS17885 ENOG4105EKV Phosphonate metabolism protein HHJ44_RS17890 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HHJ44_RS17895 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HHJ44_RS17900 ENOG4107RJJ Transcriptional regulator HHJ44_RS17910 ENOG4105EHI Phosphonate ABC transporter, periplasmic HHJ44_RS17920 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HHJ44_RS17925 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HHJ44_RS17930 ENOG4108F5E vimentin HHJ44_RS17935 ENOG4108YIV HHJ44_RS17940 ENOG4105CSH Transporter HHJ44_RS17950 ENOG4105ECM Sensor protein basS pmrB HHJ44_RS17955 ENOG4105XJC Two component transcriptional regulator (Winged helix family HHJ44_RS17960 ENOG4105DIJ Phosphoethanolamine transferase HHJ44_RS17965 ENOG4105D5Q Arginine ornithine antiporter HHJ44_RS17970 ENOG4106ZGR Transcriptional regulator HHJ44_RS17975 ENOG4105CXN decarboxylase HHJ44_RS17980 ENOG4108K2B transcriptional regulator HHJ44_RS17985 ENOG4105F8D glycoside hydrolase family 4 HHJ44_RS17990 ENOG4108R5S membrane HHJ44_RS17995 ENOG4107GFK fumarate HHJ44_RS18000 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ44_RS18005 ENOG4108MRH transcriptional regulatory protein HHJ44_RS18010 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ44_RS18015 ENOG4105VR1 Pfam:DUF1271 HHJ44_RS18020 ENOG410830R acetyltransferase HHJ44_RS18035 ENOG4105CRK lysyL-tRNA synthetase HHJ44_RS18040 ENOG4105DUX Transporter HHJ44_RS18045 ENOG4105CXN decarboxylase HHJ44_RS18050 ENOG4105D5Q Arginine ornithine antiporter HHJ44_RS18055 ENOG4108M3R transcriptional activator CadC HHJ44_RS18080 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ44_RS18090 ENOG4108YGG dna repair protein HHJ44_RS18125 ENOG4105TS0 gtp-binding protein HHJ44_RS18175 ENOG4105KNY Microcompartments protein HHJ44_RS18185 ENOG4106R3P AraC family transcriptional regulator HHJ44_RS18190 ENOG4105C2F Histidine kinase HHJ44_RS18195 ENOG4105EKQ RNA-directed DNA polymerase HHJ44_RS18210 ENOG4105F1A Pyruvate formate-lyase HHJ44_RS18220 ENOG4107R7Y intracellular protease Pfpi family HHJ44_RS18230 ENOG4108EKI Dehydrogenase HHJ44_RS18235 ENOG4105EHR propanediol utilization protein pduB HHJ44_RS18240 ENOG4105KNY Microcompartments protein HHJ44_RS18255 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HHJ44_RS18265 ENOG4107RWI ethanolamine utilization protein eutJ HHJ44_RS18270 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) HHJ44_RS18295 ENOG4105D5K Hemolysin activator protein HHJ44_RS18350 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HHJ44_RS18360 ENOG4105D5Q Arginine ornithine antiporter HHJ44_RS18365 ENOG4105CXN decarboxylase HHJ44_RS18370 ENOG4105D5Q Arginine ornithine antiporter HHJ44_RS18410 ENOG4108SIC Transcriptional regulator HHJ44_RS18415 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) HHJ44_RS18425 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HHJ44_RS18430 ENOG4108IJ0 Aspartate ammonia-lyase HHJ44_RS18435 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HHJ44_RS18440 ENOG4105DVH amino acid HHJ44_RS18455 ENOG4108ZVF (LipO)protein HHJ44_RS18460 ENOG4105MTB Uncharacterized protein YjeJ HHJ44_RS18465 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HHJ44_RS18475 ENOG4107PEH Entericidin EcnA/B family HHJ44_RS18480 ENOG4106BSU Entericidin B HHJ44_RS18485 ENOG4105KPY Small multidrug resistance protein HHJ44_RS18490 ENOG4105QNF Outer membrane lipoprotein HHJ44_RS18495 ENOG41066YJ Beta-lactamase HHJ44_RS18510 ENOG4105E33 succinate dehydrogenase HHJ44_RS18515 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ44_RS18525 ENOG4107SC7 Inner membrane transporter yjeM HHJ44_RS18530 ENOG4106V5W HHJ44_RS18535 ENOG4106CG8 Inner membrane protein YjeO HHJ44_RS18540 ENOG4105EGS Mechanosensitive ion channel HHJ44_RS18580 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HHJ44_RS18585 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HHJ44_RS18590 ENOG4105K8N protein family UPF0079, ATPase HHJ44_RS18595 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HHJ44_RS18615 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HHJ44_RS18620 ENOG4107QJR hflk protein HHJ44_RS18625 ENOG4105EPW hflc protein HHJ44_RS18645 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HHJ44_RS18650 ENOG4105C2N RNA methyltransferase TrmH family group 3 HHJ44_RS18655 ENOG4105FUX Conserved Protein HHJ44_RS18660 ENOG4108P9J Phage shock protein A HHJ44_RS18665 ENOG4107VNS Protein of unknown function (DUF2491) HHJ44_RS18670 ENOG4105Z6B inner membrane protein yjfl HHJ44_RS18675 ENOG4108KXT Conserved Protein HHJ44_RS18680 ENOG4106032 Glutathionylspermidine synthase HHJ44_RS18685 ENOG4105CSU acyl-Coa dehydrogenase HHJ44_RS18690 ENOG4105S17 UPF0379 protein yjfN HHJ44_RS18695 ENOG4105WSB biofilm stress and motility protein A HHJ44_RS18700 ENOG4108MXZ Esterase HHJ44_RS18715 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HHJ44_RS18720 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport HHJ44_RS18730 ENOG4105H6Q decarboxylase HHJ44_RS18745 ENOG4105KIT UPF0379 protein yjfY HHJ44_RS18760 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HHJ44_RS18780 ENOG4105DPW Major facilitator superfamily MFS_1 HHJ44_RS18785 ENOG4107S3R L-aspartate oxidase HHJ44_RS18790 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HHJ44_RS18795 ENOG4105E39 Enoyl-CoA hydratase HHJ44_RS18805 ENOG4105CHR reductase HHJ44_RS18815 ENOG4105FHY Opacity-associated protein A HHJ44_RS18820 ENOG4108V1T peptidylprolyl cis-trans isomerase HHJ44_RS18835 ENOG4105DXC membrane HHJ44_RS18840 ENOG4105ECR NmrA family HHJ44_RS18845 ENOG4105KVH Transcriptional regulator HHJ44_RS18850 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HHJ44_RS18855 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HHJ44_RS18860 ENOG4108UUE Transcriptional regulator HHJ44_RS18865 ENOG41061GZ Protein of unknown function (DUF1107) HHJ44_RS18870 ENOG4105C37 (CBS) domain HHJ44_RS18880 ENOG4105CFU surface antigen HHJ44_RS18885 ENOG4105MA0 exported protein HHJ44_RS18890 ENOG4108ZHD aig2 family HHJ44_RS18895 ENOG4105F0N pyrophosphate phospho-hydrolase HHJ44_RS18900 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HHJ44_RS18905 ENOG4105C2J ABC transporter HHJ44_RS18910 ENOG4107R9N ABC transporter HHJ44_RS18915 ENOG41062B0 ABC transporter, permease HHJ44_RS18925 ENOG4105DFU Cell wall formation (By similarity) HHJ44_RS18935 ENOG4105CMS peptidase U62, modulator of DNA gyrase HHJ44_RS18940 ENOG4108XVM Cytochrome b(562) HHJ44_RS18945 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HHJ44_RS18950 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HHJ44_RS18955 ENOG4105CG3 alpha amylase, catalytic region HHJ44_RS18960 ENOG4105C5Y PTS System HHJ44_RS18965 ENOG4105D4X repressor HHJ44_RS18975 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HHJ44_RS18980 ENOG4105KME endoribonuclease L-psp HHJ44_RS18995 ENOG4107C93 pyrBI operon leader peptide HHJ44_RS19005 ENOG4105CSX c4-dicarboxylate anaerobic carrier HHJ44_RS19010 ENOG4105DBV ornithine carbamoyltransferase HHJ44_RS19025 ENOG4105XEP YhcH YjgK YiaL family protein HHJ44_RS19030 ENOG4105DBV ornithine carbamoyltransferase HHJ44_RS19035 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HHJ44_RS19040 ENOG4108MJ3 acetyltransferase HHJ44_RS19045 ENOG4108M3P Membrane HHJ44_RS19050 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HHJ44_RS19055 ENOG4105MYG DNA polymerase iii, chi subunit HHJ44_RS19065 ENOG4108M8S permease YjgP YjgQ family protein HHJ44_RS19070 ENOG4108K5H permease YjgP YjgQ family protein HHJ44_RS19075 ENOG4105D7A ATP-binding protein HHJ44_RS19080 ENOG4105K2J Transcriptional regulator HHJ44_RS19085 ENOG4105C6Z Gluconate HHJ44_RS19090 ENOG4105CHR reductase HHJ44_RS19095 ENOG4105CPQ Dehydrogenase HHJ44_RS19100 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HHJ44_RS19105 ENOG4105DQ4 alcohol dehydrogenase HHJ44_RS19175 ENOG4107R3N Filamentation induced by cAMP protein fic HHJ44_RS19190 ENOG4105QEK Transcriptional regulator HHJ44_RS19200 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) HHJ44_RS19225 ENOG4106ETB IIa component HHJ44_RS19235 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HHJ44_RS19250 ENOG4105EDR glucose galactose transporter HHJ44_RS19260 ENOG4107FB0 transcriptional regulator DeoR family HHJ44_RS19280 ENOG4105E5H Transposase HHJ44_RS19285 ENOG4108YXQ IS66 Orf2 family protein HHJ44_RS19340 ENOG4105F4K antigen 43 HHJ44_RS19350 ENOG4106H6R UPF0380 protein HHJ44_RS19360 ENOG4106549 Antirestriction protein HHJ44_RS19365 ENOG4108YGG dna repair protein HHJ44_RS19375 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HHJ44_RS19430 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 HHJ44_RS19435 ENOG4108SHN Glycosyl transferase, family 2 HHJ44_RS19440 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) HHJ44_RS19450 ENOG4107W7X Aldolase HHJ44_RS19460 ENOG4105DKT Transcriptional regulator HHJ44_RS19465 ENOG4105C6Z Gluconate HHJ44_RS19470 ENOG4105C01 Dihydroxy-acid dehydratase HHJ44_RS19475 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HHJ44_RS19480 ENOG4106P37 HTH-type transcriptional regulator YjhI HHJ44_RS19485 ENOG4108PQ7 sgc region transcriptional regulator HHJ44_RS19490 ENOG4108RK0 3-epimerase HHJ44_RS19495 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ44_RS19500 ENOG4106P19 photosystem i assembly btpa HHJ44_RS19505 ENOG4105DT3 PTS system, galactitol-specific IIc component HHJ44_RS19510 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HHJ44_RS19515 ENOG4105CN9 Peptidase m42 family protein HHJ44_RS19525 ENOG4105DTA methyltransferase HHJ44_RS19530 ENOG41080VW acetyltransferase HHJ44_RS19555 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) HHJ44_RS19560 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria HHJ44_RS19565 ENOG4108W9T type 1 fimbriae regulatory protein HHJ44_RS19570 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off HHJ44_RS19580 ENOG4108S54 Fimbrial protein HHJ44_RS19585 ENOG4108NAE Fimbrial chaperone protein HHJ44_RS19590 ENOG4105CW0 outer membrane usher protein HHJ44_RS19595 ENOG4108SQA Fimbrial HHJ44_RS19600 ENOG4108T65 Fimbrial HHJ44_RS19605 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HHJ44_RS19610 ENOG4107EFN gluconate transport system permease 3 HHJ44_RS19620 ENOG4105DEI Mannitol dehydrogenase HHJ44_RS19625 ENOG4105C6F GntR Family Transcriptional Regulator HHJ44_RS19650 ENOG4107YNJ LysR family Transcriptional regulator HHJ44_RS19655 ENOG4105DYB Isoaspartyl dipeptidase HHJ44_RS19660 ENOG4108P2H Inner membrane protein YjiG HHJ44_RS19665 ENOG41074DU domain protein HHJ44_RS19675 ENOG4105CBP Major Facilitator HHJ44_RS19690 ENOG4105CIZ coA-substrate-specific enzyme activase HHJ44_RS19695 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HHJ44_RS19700 ENOG4106BRA Membrane HHJ44_RS19705 ENOG41083G8 Multidrug resistance protein MdtM HHJ44_RS19730 ENOG4105CKI cobalamin synthesis protein HHJ44_RS19735 ENOG4105VCD cytoplasmic protein HHJ44_RS19740 ENOG4105D22 carbon starvation protein HHJ44_RS19745 ENOG4105C8Q Methyl-accepting chemotaxis HHJ44_RS19755 ENOG410617M Transcriptional regulator HHJ44_RS19760 ENOG4105CPQ Dehydrogenase HHJ44_RS19770 ENOG4105RI1 glycoprotein receptor HHJ44_RS19775 ENOG4106CVF DNA replication protein HHJ44_RS19790 ENOG4105DWK Membrane HHJ44_RS19795 ENOG4108N8T regulatoR HHJ44_RS19800 ENOG4108T94 DNA-binding transcriptional activator BglJ HHJ44_RS19805 ENOG4108819 ferric iron reductase HHJ44_RS19810 ENOG4105YBH Protein of unknown function (DUF1435) HHJ44_RS19835 ENOG4108WPU DNA polymerase III subunit psi HHJ44_RS19840 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HHJ44_RS19845 ENOG4105PAD Hydrolase HHJ44_RS19930 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HHJ44_RS20120 ENOG4105K3G Periplasmic Protein HHJ44_RS20130 ENOG4108NRW Phospholipase, patatin family HHJ44_RS20135 ENOG4105EYA deoxyribonuclease HHJ44_RS20140 ENOG41076CZ activating enzyme HHJ44_RS20145 ENOG4105G0K glycine radical enzyme YjjI family HHJ44_RS20165 ENOG4105D3A purine nucleoside phosphorylase DeoD-type HHJ44_RS20175 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) HHJ44_RS20180 ENOG41062Z9 Membrane HHJ44_RS20185 ENOG4105EAC phosphoserine phosphatase HHJ44_RS20190 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HHJ44_RS20195 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HHJ44_RS20200 ENOG4105C5H ABC transporter HHJ44_RS20205 ENOG4107SC1 transglycosylase HHJ44_RS20215 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HHJ44_RS20225 ENOG4105UEI Transcriptional Regulator AraC Family HHJ44_RS20230 ENOG4108RH0 Crea protein HHJ44_RS20235 ENOG4105E3W Two component transcriptional regulator (Winged helix family HHJ44_RS20240 ENOG4105EB3 Histidine kinase HHJ44_RS20245 ENOG4105CT7 inner membrane cred family protein HHJ44_RS20250 ENOG41065U4 response regulator HHJ44_RS20255 ENOG410759A HHJ44_RS20260 ENOG4106FVC RNA methyltransferase HHJ44_RS20270 ENOG4105CFH Aspartokinase HHJ44_RS20280 ENOG4105D98 threonine synthase HHJ44_RS20285 ENOG41062C6 Protein of unknown function (DUF2502) HHJ44_RS20290 ENOG4105D1Q UPF0246 protein HHJ44_RS20295 ENOG4105BZG amino acid carrier protein HHJ44_RS20305 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ44_RS20310 ENOG4106HK8 GPR1 FUN34 yaaH family protein HHJ44_RS20315 ENOG4108QUJ UPF0174 protein YaaW HHJ44_RS20335 ENOG4105WI6 cell killing protein encoded within cryptic prophage HHJ44_RS20345 ENOG41061MV Arylsulfatase HHJ44_RS20360 ENOG41063Z6 transcriptional regulator, lysR family HHJ44_RS20370 ENOG410647N response to DNA damage stimulus HHJ44_RS20375 ENOG4105DTN riboflavin biosynthesis protein ribF HHJ44_RS20390 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HHJ44_RS20415 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HHJ44_RS20420 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HHJ44_RS20425 ENOG4108RS6 transposase HHJ44_RS20430 ENOG4108XNW Transcriptional activatory protein CaiF HHJ44_RS20440 ENOG4106YT9 Enoyl-CoA hydratase HHJ44_RS20475 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HHJ44_RS20480 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HHJ44_RS20485 ENOG4105C54 Major Facilitator superfamily HHJ44_RS20500 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HHJ44_RS20535 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HHJ44_RS20540 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HHJ44_RS20550 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HHJ44_RS20555 ENOG4105D3G Pseudouridine synthase HHJ44_RS20560 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HHJ44_RS20565 ENOG4105CQ2 DNA polymerase HHJ44_RS20570 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HHJ44_RS20585 ENOG41063TF transcriptional regulator (AraC HHJ44_RS20600 ENOG4108KF1 Membrane HHJ44_RS20610 ENOG4106SMU thiamine transporter membrane protein HHJ44_RS20615 ENOG4105DP9 ABC transporter HHJ44_RS20655 ENOG41064T2 transcriptional regulator, lysR family HHJ44_RS20660 ENOG4105C7K acetolactate synthase HHJ44_RS20665 ENOG4108ZP8 Acetolactate synthase small subunit HHJ44_RS20675 ENOG4107B7Y DNA-binding transcriptional regulator FruR HHJ44_RS20690 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HHJ44_RS20695 ENOG4105CJN penicillin-binding protein HHJ44_RS20700 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HHJ44_RS20705 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HHJ44_RS20715 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) HHJ44_RS20720 ENOG4105CNI cell division protein FtsW HHJ44_RS20735 ENOG4105CPF Cell wall formation (By similarity) HHJ44_RS20740 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HHJ44_RS20745 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HHJ44_RS20750 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HHJ44_RS20770 ENOG4105M6F mutator MutT protein HHJ44_RS20785 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HHJ44_RS20795 ENOG4105D7Q type ii secretion system HHJ44_RS20800 ENOG4107QHF type ii secretion system protein e HHJ44_RS20805 ENOG4108ZUW Major pilin subunit HHJ44_RS20810 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HHJ44_RS20815 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HHJ44_RS20820 ENOG4106A72 regulatory protein AmpE HHJ44_RS20825 ENOG4105C85 amino acid HHJ44_RS20830 ENOG4105GMB type VI secretion system effector, hcp1 family HHJ44_RS20845 ENOG41060S4 immunity protein HHJ44_RS20860 ENOG41073TP transcriptional regulator HHJ44_RS20865 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HHJ44_RS20870 ENOG4107QSN dihydrolipoamide acetyltransferase HHJ44_RS20875 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ44_RS20880 ENOG4108NST exported protein HHJ44_RS20885 ENOG4107QIJ Aconitate hydratase 2 HHJ44_RS20905 ENOG4108ZRK uncharacterized protein yacC HHJ44_RS20910 ENOG4105E3B Multicopper oxidase HHJ44_RS20915 ENOG4105DZG Dehydrogenase HHJ44_RS20920 ENOG4108UGV hypoxanthine phosphoribosyltransferase HHJ44_RS20925 ENOG41077A9 carbonic anhydrase HHJ44_RS20930 ENOG4105DA5 (ABC) transporter HHJ44_RS20935 ENOG4105E3A (ABC) transporter HHJ44_RS20940 ENOG4108YTN IIa component HHJ44_RS20945 ENOG4107BJW polysaccharide deacetylase HHJ44_RS20955 ENOG4108A32 Transposase HHJ44_RS20970 ENOG4105P0Q fimbrial-like protein YadC HHJ44_RS20975 ENOG4105SN2 fimbrial-like adhesin protein HHJ44_RS20980 ENOG4105SYG Fimbrial protein HHJ44_RS20985 ENOG4108XEY fimbrial-like adhesin protein HHJ44_RS20990 ENOG4105CW0 outer membrane usher protein HHJ44_RS20995 ENOG4108VEV chaperone HHJ44_RS21005 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HHJ44_RS21010 ENOG4105DJ0 Poly(A) Polymerase HHJ44_RS21015 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) HHJ44_RS21030 ENOG4107XID 2'-5' rna ligase HHJ44_RS21035 ENOG4105CQ7 ATP-dependent helicase HHJ44_RS21040 ENOG4105BZ4 penicillin-binding protein HHJ44_RS21045 ENOG4105E0K tonB-dependent siderophore receptor HHJ44_RS21050 ENOG4105E0A ABC, transporter HHJ44_RS21055 ENOG4105J76 Periplasmic binding protein HHJ44_RS21060 ENOG4105S6R Iron-hydroxamate transporter permease subunit HHJ44_RS21085 ENOG4105EN6 Membrane HHJ44_RS21090 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HHJ44_RS21105 ENOG4105C0H protease HHJ44_RS21110 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HHJ44_RS21130 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HHJ44_RS21155 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HHJ44_RS21160 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HHJ44_RS21165 ENOG4105KNE Phosphatidate cytidylyltransferase HHJ44_RS21170 ENOG4105DZP Membrane-associated zinc metalloprotease HHJ44_RS21180 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HHJ44_RS21210 ENOG4105C0B DNA polymerase III (alpha subunit) HHJ44_RS21220 ENOG4105CXN decarboxylase HHJ44_RS21225 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HHJ44_RS21230 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HHJ44_RS21235 ENOG4105M1T rho-binding antiterminator HHJ44_RS21245 ENOG4108VWS Yaeq family HHJ44_RS21250 ENOG4108YZN class I peptide chain release factor HHJ44_RS21255 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HHJ44_RS21260 ENOG4108UY0 (LipO)protein HHJ44_RS21270 ENOG4108R96 Methyltransferase, YaeB family HHJ44_RS21275 ENOG4108R8X outer membrane lipoprotein HHJ44_RS21280 ENOG4105D01 (LipO)protein HHJ44_RS21285 ENOG4108UMI ABC transporter, permease HHJ44_RS21290 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HHJ44_RS21295 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HHJ44_RS21325 ENOG4105CV8 reductase HHJ44_RS21330 ENOG4105HEI LysR family (Transcriptional regulator HHJ44_RS21340 ENOG4105F2W methyltransferase HHJ44_RS21345 ENOG4105E9H Lytic Murein transglycosylase HHJ44_RS21355 ENOG4105D1A Methyltransferase HHJ44_RS21365 ENOG4107RZZ dna polymerase iii epsilon subunit HHJ44_RS21375 ENOG410600K aminopeptidase HHJ44_RS21405 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HHJ44_RS21500 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HHJ44_RS21505 ENOG4108WN0 inhibitor of vertebrate lysozyme HHJ44_RS21510 ENOG4107QPN acyl-Coa dehydrogenase HHJ44_RS21520 ENOG4105E7A Glutamine amidotransferase HHJ44_RS21525 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HHJ44_RS21530 ENOG4108YS0 lipoprotein YafL HHJ44_RS21535 ENOG4108UK5 Transposase HHJ44_RS21560 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system HHJ44_RS21565 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome HHJ44_RS21570 ENOG4108HYG acetyltransferase HHJ44_RS21580 ENOG4108S2Y peptide Chain Release factor HHJ44_RS21585 ENOG4105CIN aminoacyl-histidine dipeptidase HHJ44_RS21605 ENOG4105FCK Membrane HHJ44_RS21655 ENOG4105R3P Inner membrane protein yagU HHJ44_RS21665 ENOG4105PI0 Ferredoxin HHJ44_RS21720 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HHJ44_RS21725 ENOG4105ENX hydrolase HHJ44_RS21730 ENOG410642W LysR family Transcriptional regulator HHJ44_RS21735 ENOG4105EQ2 LysR family Transcriptional regulator HHJ44_RS21740 ENOG4107SET aldo keto reductase HHJ44_RS21760 ENOG4105CV8 reductase HHJ44_RS21765 ENOG4108KBJ Inner membrane protein YkgB HHJ44_RS21770 ENOG41066GK UPF0379 protein ykgI HHJ44_RS21775 ENOG4107QN2 dihydrolipoyl dehydrogenase HHJ44_RS21780 ENOG4108K01 transcriptional regulator HHJ44_RS21785 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HHJ44_RS21790 ENOG4107QR9 Iron-sulfur cluster binding protein HHJ44_RS21795 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HHJ44_RS21835 ENOG4105BZU Histidine kinase HHJ44_RS21840 ENOG4108W9T type 1 fimbriae regulatory protein HHJ44_RS21860 ENOG4105C94 Transporter HHJ44_RS21865 ENOG4105BZU Histidine kinase HHJ44_RS21870 ENOG4108NUU Transcriptional regulator HHJ44_RS21875 ENOG4105SZ2 membrAne HHJ44_RS21880 ENOG4107SNB ankyrin repeat protein YahD HHJ44_RS21885 ENOG4105N16 Protein of unknown function (DUF2877) HHJ44_RS21890 ENOG4107R1Q Membrane protein FdrA HHJ44_RS21895 ENOG4107REC cytoplasmic protein HHJ44_RS21900 ENOG4105C5B carbamate kinase HHJ44_RS21905 ENOG4105DZC cytosine deaminase HHJ44_RS21915 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HHJ44_RS21920 ENOG4105C2J ABC transporter HHJ44_RS21925 ENOG4105CNN ABC, transporter HHJ44_RS21930 ENOG4105CNN ABC, transporter HHJ44_RS21935 ENOG4105DQ4 alcohol dehydrogenase HHJ44_RS21945 ENOG4105E82 cytochrome subunit of dehydrogenase HHJ44_RS21950 ENOG4105TDT uncharacterized protein yahO HHJ44_RS21960 ENOG4105CR4 methylisocitrate lyase HHJ44_RS21965 ENOG4105BZN citrate synthase HHJ44_RS21970 ENOG4105DXD 2-methylcitrate dehydratase HHJ44_RS21975 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HHJ44_RS21980 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HHJ44_RS21985 ENOG4105DZC cytosine deaminase HHJ44_RS21990 ENOG4108UW5 maltose o-acetyltransferase HHJ44_RS21995 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) HHJ44_RS22005 ENOG4105ETE Transcriptional regulator (LacI family HHJ44_RS22015 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HHJ44_RS22035 ENOG4105SRB Uncharacterized protein yaiO HHJ44_RS22045 ENOG4108PBI Polysaccharide metabolism HHJ44_RS22050 ENOG4107W19 lmbE family HHJ44_RS22055 ENOG4106FTQ Taurine ABC transporter, periplasmic HHJ44_RS22060 ENOG4108IY8 ABC, transporter HHJ44_RS22065 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HHJ44_RS22070 ENOG4105E2B Taurine dioxygenase HHJ44_RS22075 ENOG4105D52 delta-aminolevulinic acid dehydratase HHJ44_RS22085 ENOG4108PNB DNA-binding transcriptional regulator HHJ44_RS22090 ENOG4107R6D beta-lactam binding protein AmpH HHJ44_RS22095 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HHJ44_RS22100 ENOG4107QS8 (LipO)protein HHJ44_RS22105 ENOG4105FR5 inner membrane protein YaiY HHJ44_RS22110 ENOG4105UNH Membrane HHJ44_RS22115 ENOG4105CPF Cell wall formation (By similarity) HHJ44_RS22130 ENOG4105G6Z alkaline phosphatase HHJ44_RS22135 ENOG4105VIF phosphate starvation-inducible protein HHJ44_RS22140 ENOG4105BZU Histidine kinase HHJ44_RS22145 ENOG4105II7 pyrroline-5-carboxylate reductase HHJ44_RS22160 ENOG4105SS3 HHJ44_RS22165 ENOG4105HBA AroM protein HHJ44_RS22190 ENOG4105DKQ ROK family HHJ44_RS22195 ENOG4105F27 Major Facilitator HHJ44_RS22200 ENOG4105EYH Exonuclease HHJ44_RS22205 ENOG4107RH8 nuclease SbcCD subunit D HHJ44_RS22210 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ44_RS22215 ENOG4105BZU Histidine kinase HHJ44_RS22220 ENOG4105CWM branched-chain amino acid transport system II carrier protein HHJ44_RS22225 ENOG4105C85 amino acid HHJ44_RS22230 ENOG4107R28 alpha amylase, catalytic region HHJ44_RS22250 ENOG4105VIE preprotein translocase, subunit YajC HHJ44_RS22255 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ44_RS22260 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HHJ44_RS22265 ENOG4105N1F Hnh endonuclease HHJ44_RS22270 ENOG4105DRB nucleoside-specific channel-forming protein HHJ44_RS22275 ENOG4108KIC (LipO)protein HHJ44_RS22285 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HHJ44_RS22300 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HHJ44_RS22305 ENOG4108ZAI phosphatidylglycerophosphatase a HHJ44_RS22310 ENOG4105CPC Aldo Keto reductase HHJ44_RS22320 ENOG4105CTB Polyprenyl synthetase HHJ44_RS22335 ENOG4107S0N DJ-1 family HHJ44_RS22340 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HHJ44_RS22350 ENOG4107RDB Major Facilitator HHJ44_RS22360 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HHJ44_RS22365 ENOG4105CCU oxidase (Subunit III) HHJ44_RS22370 ENOG4105BZ9 Cytochrome C oxidase, subunit I HHJ44_RS22375 ENOG4105E2S oxidase) subunit II HHJ44_RS22380 ENOG4105EYM Major Facilitator superfamily HHJ44_RS22385 ENOG4105IEY (LipO)protein HHJ44_RS22390 ENOG4105M85 Bola protein HHJ44_RS22410 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HHJ44_RS22415 ENOG4105K70 DNA-binding protein HHJ44_RS22420 ENOG4105EIN peptidylprolyl cis-trans isomerase HHJ44_RS22425 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HHJ44_RS22430 ENOG4108TGP Thioesterase superfamily protein HHJ44_RS22440 ENOG4108NFA extracellular solute-binding protein HHJ44_RS22450 ENOG4108XM1 transcriptional regulator AsnC family HHJ44_RS22455 ENOG4105BZ1 (ABC) transporter HHJ44_RS22460 ENOG4105BZ1 (ABC) transporter HHJ44_RS22465 ENOG4108YZA Nitrogen regulatory protein pii HHJ44_RS22470 ENOG4105BZU Histidine kinase HHJ44_RS22475 ENOG4105C29 acyl-CoA thioesterase HHJ44_RS22480 ENOG4108MNP Glycoprotein polysaccharide metabolism HHJ44_RS22485 ENOG41080UX Methyltransferase HHJ44_RS22495 ENOG4105KCV RNA signal recognition particle 4.5S RNA HHJ44_RS22500 ENOG41066DG (EAL) domain protein HHJ44_RS22505 ENOG4105GSJ Inner membrane protein ylaC HHJ44_RS22510 ENOG4108UW5 maltose o-acetyltransferase HHJ44_RS22515 ENOG4105KF5 hemolysin expression-modulating protein HHJ44_RS22520 ENOG4108UKR Biofilm formation regulator YbaJ HHJ44_RS22525 ENOG4105BZS acriflavin resistance protein HHJ44_RS22530 ENOG4105C1P efflux transporter, rnd family, mfp subunit HHJ44_RS22535 ENOG4107XI7 Tetr family transcriptional regulator HHJ44_RS22540 ENOG4105EGS Mechanosensitive ion channel HHJ44_RS22545 ENOG4106428 Protein of unknown function (DUF2496) HHJ44_RS22550 ENOG4108URS primosomal replication protein n'' HHJ44_RS22555 ENOG4105WD1 Membrane HHJ44_RS22565 ENOG4107QMP dna polymerase iii subunits gamma and tau HHJ44_RS22600 ENOG4107RE1 Inosine-guanosine kinase HHJ44_RS22605 ENOG4105CKD glutathione-regulated potassium-efflux system protein HHJ44_RS22610 ENOG4105EU0 Major facilitator Superfamily HHJ44_RS22615 ENOG4105CGH 5'-nucleotidase HHJ44_RS22630 ENOG4108Z66 YbaK ebsC protein HHJ44_RS22635 ENOG4105MBR gumn family HHJ44_RS22640 ENOG41080ET plasmid maintenance system killer protein HHJ44_RS22645 ENOG41081XE plasmid maintenance system antidote protein, xre family HHJ44_RS22650 ENOG4105C59 p-type ATPase HHJ44_RS22655 ENOG4105CSV Glutaminase HHJ44_RS22660 ENOG4107RY6 amino acid HHJ44_RS22690 ENOG4105G5H Membrane HHJ44_RS22695 ENOG4107QX8 SPFH domain, Band 7 family protein HHJ44_RS22700 ENOG41083J0 (ABC) transporter HHJ44_RS22705 ENOG4105C4B ABC transporter, permease HHJ44_RS22710 ENOG4107QR8 Thioredoxin HHJ44_RS22715 ENOG4105E1F short-chain dehydrogenase reductase HHJ44_RS22720 ENOG4108UJV acyl-CoA thioesterase i HHJ44_RS22725 ENOG4108I0Y (ABC) transporter HHJ44_RS22730 ENOG4105CV6 ABC transporter, permease HHJ44_RS22755 ENOG41060W2 glyoxylate carboligase HHJ44_RS22760 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HHJ44_RS22765 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HHJ44_RS22770 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HHJ44_RS22780 ENOG4105DTE Xanthine uracil vitamin C permease HHJ44_RS22785 ENOG4105BZW Glycerate kinase HHJ44_RS22790 ENOG4105S0E allantoin catabolism protein HHJ44_RS22795 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HHJ44_RS22800 ENOG4105DG4 malate L-lactate dehydrogenase HHJ44_RS22805 ENOG4107R1Q Membrane protein FdrA HHJ44_RS22810 ENOG4107REC cytoplasmic protein HHJ44_RS22815 ENOG4105G5A Protein of unknown function (DUF2877) HHJ44_RS22820 ENOG4105C5B carbamate kinase HHJ44_RS22825 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HHJ44_RS22830 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HHJ44_RS22845 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HHJ44_RS22855 ENOG4105S2T inner membrane protein YbcI HHJ44_RS22860 ENOG4105WQ3 Rna-binding protein HHJ44_RS22880 ENOG4105UZW Tail fiber assembly protein HHJ44_RS22885 ENOG4108WF3 methyltransferase HHJ44_RS22890 ENOG4108NC2 Outer membrane protease HHJ44_RS22895 ENOG4105QUW HHJ44_RS22900 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HHJ44_RS22905 ENOG410802X bacteriophage n4 adsorption protein b HHJ44_RS22910 ENOG4105GR3 Histidine kinase HHJ44_RS22915 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ44_RS22920 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HHJ44_RS22925 ENOG410624V efflux system protein HHJ44_RS22930 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HHJ44_RS22935 ENOG4108IJF Heavy metal efflux pump, CzcA HHJ44_RS22940 ENOG4105C85 amino acid HHJ44_RS22945 ENOG4105CUY Mechanosensitive ion channel HHJ44_RS22950 ENOG4108RCM Nitroreductase HHJ44_RS22955 ENOG4105MSB protein, conserved in bacteria HHJ44_RS22960 ENOG4105WQ6 Membrane HHJ44_RS22975 ENOG4108TSE Transferase HHJ44_RS22980 ENOG4107RNH Outer membrane receptor FepA HHJ44_RS22985 ENOG4105E93 esterase HHJ44_RS22990 ENOG41085A6 mbth domain-containing protein HHJ44_RS23000 ENOG4108QY5 Ferric enterobactin transport protein HHJ44_RS23005 ENOG4105E0A ABC, transporter HHJ44_RS23010 ENOG4105TVJ transport system, permease HHJ44_RS23015 ENOG4105DQ5 transport system permease protein HHJ44_RS23025 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HHJ44_RS23030 ENOG4105E4F Isochorismate synthase HHJ44_RS23035 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HHJ44_RS23040 ENOG4105WQI isochorismatase HHJ44_RS23045 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HHJ44_RS23050 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HHJ44_RS23055 ENOG4105D22 carbon starvation protein HHJ44_RS23060 ENOG4105VCD cytoplasmic protein HHJ44_RS23065 ENOG4107SCQ Iron-containing alcohol dehydrogenase HHJ44_RS23070 ENOG4105CHM Aminotransferase HHJ44_RS23075 ENOG4105GTN ParB Domain Protein Nuclease HHJ44_RS23080 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HHJ44_RS23085 ENOG4105DQS Transcriptional regulator HHJ44_RS23090 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HHJ44_RS23095 ENOG4105D3R alkyl hydroperoxide reductase HHJ44_RS23100 ENOG4108JU3 Alkyl hydroperoxide reductase HHJ44_RS23105 ENOG4108U51 Universal stress protein HHJ44_RS23110 ENOG4105NXH GreA GreB family elongation factor HHJ44_RS23115 ENOG4105KTS ribonuclease HHJ44_RS23120 ENOG4107QPK )-transporter HHJ44_RS23135 ENOG4105CHY citrate lyase, alpha HHJ44_RS23140 ENOG4105CI0 Citrate lyase HHJ44_RS23150 ENOG4105DUA (citrate (pro-3S)-lyase ligase HHJ44_RS23155 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HHJ44_RS23160 ENOG4106YYS transcriptional regulatory protein HHJ44_RS23165 ENOG4105CEE C4-dicarboxylate transporter HHJ44_RS23190 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HHJ44_RS23210 ENOG4105DZ1 carboxypeptidase HHJ44_RS23215 ENOG4105K6T rare lipoprotein A HHJ44_RS23220 ENOG4105CNI cell division protein FtsW HHJ44_RS23225 ENOG4105CJN penicillin-binding protein HHJ44_RS23235 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HHJ44_RS23240 ENOG4108TGR phosphatase HHJ44_RS23250 ENOG4105DJF DNA polymerase III, delta' subunit HHJ44_RS23265 ENOG4107PAI alpha helical protein HHJ44_RS23275 ENOG4105CDA abc transporter atp-binding protein HHJ44_RS23280 ENOG4105DRP amino acid AbC transporter HHJ44_RS23285 ENOG4105EAD ABC transporter HHJ44_RS23290 ENOG4107RP9 extracellular solute-binding protein, family 3 HHJ44_RS23295 ENOG4107U91 Rhomboid family HHJ44_RS23300 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HHJ44_RS23305 ENOG4108JU5 Magnesium and cobalt efflux protein HHJ44_RS23315 ENOG4105C9A Phoh family HHJ44_RS23325 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HHJ44_RS23365 ENOG4105CAQ asparagine synthetase HHJ44_RS23370 ENOG4105D4U had-superfamily hydrolase, subfamily iia HHJ44_RS23375 ENOG4105E2R ROK family HHJ44_RS23380 ENOG4105CE4 GlcNAc 6-P deacetylase HHJ44_RS23390 ENOG4105CI1 PTS System HHJ44_RS23415 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HHJ44_RS23420 ENOG4108JB8 alcohol dehydrogenase HHJ44_RS23425 ENOG4107S2N Type III effector Hrp-dependent HHJ44_RS23430 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HHJ44_RS23435 ENOG4105MVE transcriptional regulator HHJ44_RS23450 ENOG4105GX6 (LipO)protein HHJ44_RS23455 ENOG41090R7 Ferric uptake HHJ44_RS23465 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HHJ44_RS23470 ENOG4105NNH LexA regulated protein HHJ44_RS23475 ENOG4105EV9 Alpha Beta Hydrolase HHJ44_RS23480 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HHJ44_RS23485 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HHJ44_RS23490 ENOG4105D5Q Arginine ornithine antiporter HHJ44_RS23495 ENOG4105CXN decarboxylase HHJ44_RS23505 ENOG4105EEX Two component transcriptional regulator (Winged helix family HHJ44_RS23510 ENOG4105C08 Histidine kinase HHJ44_RS23535 ENOG4105XIQ Protein of unknown function (DUF2517) HHJ44_RS23540 ENOG4107SEY Conserved Protein HHJ44_RS23545 ENOG4105CVP deoxyribo-dipyrimidine photolyase HHJ44_RS23550 ENOG4105DUX Transporter HHJ44_RS23555 ENOG4107QNR UPF0135 protein HHJ44_RS23560 ENOG4105P4J Allophanate hydrolase, subunit 1 HHJ44_RS23565 ENOG4107R7A Allophanate hydrolase subunit 2 HHJ44_RS23580 ENOG4108KK1 membrane protein AbrB duplication HHJ44_RS23585 ENOG4108MY7 Fimbrial HHJ44_RS23590 ENOG4105BZN citrate synthase HHJ44_RS23600 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HHJ44_RS23605 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HHJ44_RS23610 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HHJ44_RS23615 ENOG4105E33 succinate dehydrogenase HHJ44_RS23620 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HHJ44_RS23625 ENOG4105C7S Dehydrogenase HHJ44_RS23635 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HHJ44_RS23645 ENOG4105C4M (Ubiquinol oxidase) subunit I HHJ44_RS23650 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HHJ44_RS23660 ENOG4105KJB cyd operon protein YbgE HHJ44_RS23665 ENOG4107YD3 Thioesterase HHJ44_RS23670 ENOG4105E02 MotA TolQ exbB proton channel HHJ44_RS23680 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HHJ44_RS23690 ENOG4105KCK Peptidoglycan-associated lipoprotein HHJ44_RS23695 ENOG4105UFD tol-pal system protein YbgF HHJ44_RS23740 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HHJ44_RS23745 ENOG4105PGM cation diffusion facilitator family transporter HHJ44_RS23750 ENOG4105JND homeobox protein HHJ44_RS23755 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HHJ44_RS23765 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HHJ44_RS23775 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HHJ44_RS23780 ENOG4105CMR udp-glucose 4-epimerase HHJ44_RS23785 ENOG4105DKW ABC transporter HHJ44_RS23790 ENOG4105F4R Transcriptional regulator mode HHJ44_RS23800 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HHJ44_RS23805 ENOG4105E0C molybdate abc transporter HHJ44_RS23810 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) HHJ44_RS23815 ENOG4108K4B hydrolase HHJ44_RS23825 ENOG4105F04 LysR family Transcriptional regulator HHJ44_RS23830 ENOG4105C7F AcnD-accessory protein PrpF HHJ44_RS23840 ENOG4107QM5 aconitate hydratase HHJ44_RS23845 ENOG4105NBR Pectinesterase HHJ44_RS23850 ENOG4108V1U phospholipid-binding protein HHJ44_RS23855 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HHJ44_RS23870 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HHJ44_RS23875 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HHJ44_RS23885 ENOG4105CHW UPF0052 protein HHJ44_RS23895 ENOG4108RIR Molybdenum cofactor biosynthesis protein HHJ44_RS23905 ENOG4105M00 molybdopterin converting factor, subunit 1 HHJ44_RS23910 ENOG4108ZAF Molybdopterin HHJ44_RS23915 ENOG4105HFZ Membrane HHJ44_RS23920 ENOG410733J conserved inner membrane protein HHJ44_RS23925 ENOG4107UXM Membrane HHJ44_RS23930 ENOG4105DZQ phospholipase D Transphosphatidylase HHJ44_RS23935 ENOG4105X23 Endonuclease Exonuclease phosphatase HHJ44_RS23940 ENOG4105I9U inner membrane protein ybhQ HHJ44_RS23945 ENOG4107QWP ABC-2 type transporter HHJ44_RS23950 ENOG4107QWP ABC-2 type transporter HHJ44_RS23955 ENOG4105CJ1 ABC, transporter HHJ44_RS23960 ENOG4105D0S secretion protein (HlyD HHJ44_RS23965 ENOG4107MVR Transcriptional regulator HHJ44_RS23970 ENOG4105C1J atp-dependent rna helicase HHJ44_RS23980 ENOG4105DVT helicase HHJ44_RS23985 ENOG4108MTB glycosyl transferase family HHJ44_RS23990 ENOG4105DG4 malate L-lactate dehydrogenase HHJ44_RS24000 ENOG4105VR4 UPF0379 protein ybiJ HHJ44_RS24005 ENOG4105KSC Transcriptional regulator, TraR DksA family HHJ44_RS24020 ENOG4105ZY9 UPF0379 protein ybiM HHJ44_RS24030 ENOG4105D8X mechanosensitive ion channel HHJ44_RS24035 ENOG4105CDA abc transporter atp-binding protein HHJ44_RS24040 ENOG4105E5Q amino acid AbC transporter HHJ44_RS24045 ENOG4107R0W ABC transporter HHJ44_RS24055 ENOG4107AQZ Membrane HHJ44_RS24065 ENOG4108T1M outer membrane protein x HHJ44_RS24070 ENOG4108I6E Sulfatase HHJ44_RS24080 ENOG4105KST dependent repressor HHJ44_RS24085 ENOG4105F4P )-transporter HHJ44_RS24090 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HHJ44_RS24095 ENOG4105C5H ABC transporter HHJ44_RS24100 ENOG4108HCJ Hydrolase HHJ44_RS24110 ENOG4105F1A Pyruvate formate-lyase HHJ44_RS24115 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HHJ44_RS24120 ENOG4105D06 uba thif-type nad fad binding protein HHJ44_RS24125 ENOG4105CVM Molybdenum cofactor synthesis domain protein HHJ44_RS24130 ENOG4105D44 asparaginase HHJ44_RS24155 ENOG4105BZU Histidine kinase HHJ44_RS24160 ENOG41064RH membrane protein YliF HHJ44_RS24170 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HHJ44_RS24175 ENOG4105D8V Glucose sorbosone dehydrogenase HHJ44_RS24180 ENOG4108TGY Glutathione S-transferase HHJ44_RS24185 ENOG4105DZ1 carboxypeptidase HHJ44_RS24190 ENOG4107FB0 transcriptional regulator DeoR family HHJ44_RS24195 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HHJ44_RS24200 ENOG4107QF7 multi-drug HHJ44_RS24210 ENOG4108HCJ Hydrolase HHJ44_RS24215 ENOG4106UW1 Major Facilitator superfamily HHJ44_RS24220 ENOG4108RFG Tetr family transcriptional regulator HHJ44_RS24265 ENOG4108BUD transposase HHJ44_RS24280 ENOG4105I1J Autotransporter HHJ44_RS24315 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HHJ44_RS24385 ENOG4106RMF ParB family HHJ44_RS24455 ENOG4107ENK receptor HHJ44_RS24495 ENOG41080HT Transcriptional regulator, arsr family HHJ44_RS24500 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase HHJ44_RS24520 ENOG41063SR receptor HHJ44_RS24540 ENOG4105I1J Autotransporter HHJ44_RS24565 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HHJ44_RS24575 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HHJ44_RS24590 ENOG4107SJW iron permease, FTR1 HHJ44_RS24595 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) HHJ44_RS24600 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HHJ44_RS24615 ENOG4108BUD transposase HHJ44_RS24665 ENOG4108BUD transposase HHJ44_RS24735 ENOG4108BUD transposase HHJ44_RS24760 ENOG4105EQW The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) HHJ44_RS24765 ENOG4108S1C Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) HHJ44_RS24770 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HHJ44_RS24775 ENOG4105BZU Histidine kinase HHJ44_RS24780 ENOG4108BUD transposase HHJ44_RS24795 ENOG4107CBI conjugal transfer fertility inhibition protein HHJ44_RS24835 ENOG4108BUD transposase HHJ44_RS24925 ENOG41074AV Hok/gef family HHJ44_RS24945 ENOG4105FEQ ParB domain protein nuclease HHJ44_RS24965 ENOG4108BUD transposase HHJ44_RS24985 ENOG4106JVB Replication Protein HHJ44_RS25020 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) HHJ44_RS25050 ENOG4105VEQ Cold shock protein HHJ44_RS25055 ENOG4106J5W DNA polymerase III (alpha subunit) HHJ44_RS25085 ENOG41090BQ Glutaredoxin HHJ44_RS25195 ENOG410685N tail fiber protein HHJ44_RS25240 ENOG4108NYK Tape measure protein HHJ44_RS25290 ENOG4107VGF ig domain protein group 2 domain protein HHJ44_RS25335 ENOG4105FA0 parb-like partition protein HHJ44_RS25340 ENOG410636K Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity) HHJ44_RS25345 ENOG4105CB5 ATP-dependent DNA helicase recG HHJ44_RS25445 ENOG4105D1F ATP-binding protein HHJ44_RS25450 ENOG4105KT5 UmuD protein HHJ44_RS25460 ENOG4105MPK DNA polymerase III subunit theta HHJ44_RS25535 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) HHJ44_RS25565 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HHJ44_RS25580 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) HHJ44_RS25590 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ44_RS25595 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HHJ44_RS25620 ENOG410607W Transposase