locus-tag	class	description
HHJ44_RS00015	COG1250	3-hydroxyacyl-CoA dehydrogenase
HHJ44_RS00020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHJ44_RS00025	COG1960	acyl-CoA dehydrogenase activity
HHJ44_RS00060	COG0154	amidase activity
HHJ44_RS00085	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HHJ44_RS00095	COG0582	viral genome integration into host DNA
HHJ44_RS00105	COG0534	Mate efflux family protein
HHJ44_RS00115	COG0583	DNA-binding transcription factor activity
HHJ44_RS00120	COG0583	DNA-binding transcription factor activity
HHJ44_RS00145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHJ44_RS00150	COG0477	Major facilitator Superfamily
HHJ44_RS00160	COG1388	LysM domain
HHJ44_RS00160	COG1470	cell adhesion involved in biofilm formation
HHJ44_RS00165	COG1470	cell adhesion involved in biofilm formation
HHJ44_RS00165	COG1388	LysM domain
HHJ44_RS00170	COG2373	Large extracellular alpha-helical protein
HHJ44_RS00170	COG4932	domain protein
HHJ44_RS00170	COG1388	LysM domain
HHJ44_RS00175	COG4771	TonB-dependent receptor
HHJ44_RS00180	COG1021	2,3-dihydroxybenzoate-AMP ligase
HHJ44_RS00200	COG3433	isochorismatase activity
HHJ44_RS00200	COG2226	methyltransferase
HHJ44_RS00200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HHJ44_RS00215	COG1132	(ABC) transporter
HHJ44_RS00220	COG2814	Major facilitator Superfamily
HHJ44_RS00230	COG0582	viral genome integration into host DNA
HHJ44_RS00375	COG0582	viral genome integration into host DNA
HHJ44_RS00380	COG3443	Belongs to the bacterial solute-binding protein 9 family
HHJ44_RS00385	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HHJ44_RS00390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HHJ44_RS00395	COG2351	hydroxyisourate hydrolase activity
HHJ44_RS00400	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS00405	COG2205	protein histidine kinase activity
HHJ44_RS00415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHJ44_RS00425	COG1418	mRNA catabolic process
HHJ44_RS00430	COG0270	DNA (cytosine-5-)-methyltransferase activity
HHJ44_RS00435	COG3727	T/G mismatch-specific endonuclease activity
HHJ44_RS00440	COG0697	spore germination
HHJ44_RS00445	COG2354	Protein conserved in bacteria
HHJ44_RS00450	COG5475	Uncharacterized small protein (DUF2158)
HHJ44_RS00455	COG3706	GGDEF domain
HHJ44_RS00460	COG3769	mannosylglycerate metabolic process
HHJ44_RS00475	COG2197	response regulator
HHJ44_RS00480	COG1684	flagellar biosynthetic protein fliR
HHJ44_RS00485	COG1987	bacterial-type flagellum assembly
HHJ44_RS00490	COG1338	Plays a role in the flagellum-specific transport system
HHJ44_RS00495	COG3190	flagellar
HHJ44_RS00500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHJ44_RS00505	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHJ44_RS00510	COG1580	Controls the rotational direction of flagella during chemotaxis
HHJ44_RS00515	COG3144	bacterial-type flagellum assembly
HHJ44_RS00520	COG2882	bacterial-type flagellum organization
HHJ44_RS00525	COG1157	protein secretion by the type III secretion system
HHJ44_RS00530	COG1317	bacterial-type flagellum organization
HHJ44_RS00535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHJ44_RS00540	COG1766	The M ring may be actively involved in energy transduction
HHJ44_RS00550	COG2076	Multidrug Resistance protein
HHJ44_RS00555	COG1881	PFAM PEBP family protein
HHJ44_RS00560	COG2207	Transcriptional regulator
HHJ44_RS00575	COG2135	peptidase activity
HHJ44_RS00580	COG0425	Belongs to the sulfur carrier protein TusA family
HHJ44_RS00585	COG2391	methyltransferase activity
HHJ44_RS00595	COG0366	Alpha amylase catalytic
HHJ44_RS00605	COG1516	flagellar protein fliS
HHJ44_RS00610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHJ44_RS00620	COG1191	sigma factor activity
HHJ44_RS00650	COG2197	response regulator
HHJ44_RS00665	COG2197	response regulator
HHJ44_RS00695	COG3318	Belongs to the UPF0149 family
HHJ44_RS00695	COG3012	SEC-C Motif Domain Protein
HHJ44_RS00700	COG0814	amino acid
HHJ44_RS00710	COG1528	Iron-storage protein
HHJ44_RS00730	COG1528	Iron-storage protein
HHJ44_RS00735	COG1879	ABC-type sugar transport system periplasmic component
HHJ44_RS00745	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ44_RS00750	COG1877	trehalose-phosphatase activity
HHJ44_RS00760	COG0589	response to stress
HHJ44_RS00775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HHJ44_RS00780	COG1360	Flagellar Motor Protein
HHJ44_RS00785	COG2198	Histidine kinase
HHJ44_RS00785	COG0643	Histidine kinase
HHJ44_RS00790	COG0835	chemotaxis
HHJ44_RS00795	COG0840	transmembrane signaling receptor activity
HHJ44_RS00805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HHJ44_RS00815	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS00820	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HHJ44_RS00825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHJ44_RS00830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHJ44_RS00845	COG3102	Protein conserved in bacteria
HHJ44_RS00855	COG3005	denitrification pathway
HHJ44_RS00860	COG0243	molybdopterin cofactor binding
HHJ44_RS00875	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HHJ44_RS00880	COG1801	Protein of unknown function DUF72
HHJ44_RS00885	COG1335	isochorismatase
HHJ44_RS00895	COG0494	nUDIX hydrolase
HHJ44_RS00900	COG0217	transcriptional regulatory protein
HHJ44_RS00930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HHJ44_RS00940	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HHJ44_RS00945	COG0739	heme binding
HHJ44_RS00950	COG1560	Kdo2-lipid A biosynthetic process
HHJ44_RS00955	COG0469	pyruvate kinase activity
HHJ44_RS00960	COG1737	Transcriptional regulator
HHJ44_RS00965	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHJ44_RS00970	COG0129	dihydroxy-acid dehydratase activity
HHJ44_RS00975	COG0800	Aldolase
HHJ44_RS00985	COG3141	response to X-ray
HHJ44_RS00995	COG2979	Protein of unknown function (DUF533)
HHJ44_RS01000	COG1770	oligopeptidase
HHJ44_RS01005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HHJ44_RS01010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HHJ44_RS01020	COG2372	response to copper ion
HHJ44_RS01025	COG1276	copper resistance
HHJ44_RS01035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HHJ44_RS01055	COG3008	intermembrane lipid transfer
HHJ44_RS01060	COG2995	paraquat-inducible protein a
HHJ44_RS01065	COG1956	GAF domain-containing protein
HHJ44_RS01075	COG0793	Belongs to the peptidase S41A family
HHJ44_RS01085	COG2814	Major facilitator Superfamily
HHJ44_RS01090	COG1414	Transcriptional regulator
HHJ44_RS01120	COG2226	methyltransferase
HHJ44_RS01135	COG3716	PTS system mannose fructose sorbose family IID component
HHJ44_RS01140	COG3715	PTS system
HHJ44_RS01145	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS01145	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS01150	COG1253	flavin adenine dinucleotide binding
HHJ44_RS01155	COG2200	EAL domain
HHJ44_RS01160	COG1760	l-serine dehydratase
HHJ44_RS01170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHJ44_RS01185	COG0251	oxidation-reduction process
HHJ44_RS01190	COG1199	ATP-dependent helicase activity
HHJ44_RS01195	COG1214	PFAM Peptidase M22, glycoprotease
HHJ44_RS01200	COG3065	identical protein binding
HHJ44_RS01205	COG0318	PFAM AMP-dependent synthetase and ligase
HHJ44_RS01210	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HHJ44_RS01215	COG0583	DNA-binding transcription factor activity
HHJ44_RS01225	COG3615	Tellurite resistance protein tehB
HHJ44_RS01235	COG2261	transglycosylase associated protein
HHJ44_RS01250	COG2203	Gaf domain
HHJ44_RS01250	COG2199	diguanylate cyclase activity
HHJ44_RS01255	COG3042	response to heat
HHJ44_RS01260	COG3189	MarR family transcriptional regulator
HHJ44_RS01265	COG2807	transmembrane transport
HHJ44_RS01270	COG2207	Transcriptional regulator
HHJ44_RS01285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHJ44_RS01290	COG2199	diguanylate cyclase activity
HHJ44_RS01295	COG2199	diguanylate cyclase activity
HHJ44_RS01305	COG2766	serine protein kinase
HHJ44_RS01310	COG3713	MltA-interacting MipA family protein
HHJ44_RS01315	COG0656	L-ascorbic acid biosynthetic process
HHJ44_RS01320	COG0676	glucose-6-phosphate 1-epimerase activity
HHJ44_RS01325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HHJ44_RS01335	COG3139	Protein of unknown function (DUF1315)
HHJ44_RS01340	COG1063	alcohol dehydrogenase
HHJ44_RS01345	COG2271	Major facilitator Superfamily
HHJ44_RS01350	COG1063	alcohol dehydrogenase
HHJ44_RS01355	COG0191	fructose-bisphosphate aldolase activity
HHJ44_RS01360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS01365	COG0667	Aldo Keto reductase
HHJ44_RS01370	COG1349	DNA-binding transcription factor activity
HHJ44_RS01375	COG2814	Major facilitator Superfamily
HHJ44_RS01380	COG1335	isochorismatase
HHJ44_RS01385	COG0252	asparaginase activity
HHJ44_RS01390	COG0616	signal peptide processing
HHJ44_RS01395	COG0778	Nitroreductase
HHJ44_RS01405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHJ44_RS01410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HHJ44_RS01420	COG0494	nUDIX hydrolase
HHJ44_RS01425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHJ44_RS01430	COG2897	thiosulfate sulfurtransferase activity
HHJ44_RS01435	COG4136	ATPase activity
HHJ44_RS01440	COG4135	transport system, permease component
HHJ44_RS01445	COG4134	Bacterial extracellular solute-binding protein
HHJ44_RS01450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHJ44_RS01455	COG0398	Pfam SNARE associated Golgi protein
HHJ44_RS01465	COG0398	Pfam SNARE associated Golgi protein
HHJ44_RS01470	COG0708	Exodeoxyribonuclease III
HHJ44_RS01500	COG3678	ATP-independent chaperone mediated protein folding
HHJ44_RS01510	COG0322	excinuclease ABC activity
HHJ44_RS01520	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ44_RS01525	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HHJ44_RS01530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HHJ44_RS01535	COG1447	Phosphotransferase system cellobiose-specific component IIA
HHJ44_RS01540	COG2169	Transcriptional regulator
HHJ44_RS01540	COG1917	Cupin 2, conserved barrel domain protein
HHJ44_RS01545	COG1486	melibiose metabolic process
HHJ44_RS01555	COG0753	catalase activity
HHJ44_RS01570	COG1988	membrane-bound metal-dependent
HHJ44_RS01575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HHJ44_RS01585	COG3001	Fructosamine kinase
HHJ44_RS01595	COG1105	Belongs to the carbohydrate kinase PfkB family
HHJ44_RS01600	COG3137	Salt-induced outer membrane protein
HHJ44_RS01660	COG0386	Belongs to the glutathione peroxidase family
HHJ44_RS01670	COG0791	NLP P60 protein
HHJ44_RS01675	COG2200	EAL domain
HHJ44_RS01685	COG4256	Hemin uptake protein
HHJ44_RS01690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHJ44_RS01700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHJ44_RS01700	COG0574	Belongs to the PEP-utilizing enzyme family
HHJ44_RS01705	COG0318	PFAM AMP-dependent synthetase and ligase
HHJ44_RS01710	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HHJ44_RS01715	COG0644	oxidoreductase
HHJ44_RS01720	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HHJ44_RS01725	COG2086	electron transfer activity
HHJ44_RS01730	COG1917	Cupin 2, conserved barrel domain protein
HHJ44_RS01730	COG2207	Transcriptional regulator
HHJ44_RS01735	COG1960	acyl-CoA dehydrogenase activity
HHJ44_RS01740	COG4670	ketone body catabolic process
HHJ44_RS01755	COG2271	Major facilitator Superfamily
HHJ44_RS01760	COG0738	Major facilitator superfamily
HHJ44_RS01775	COG0628	permease
HHJ44_RS01780	COG0277	FAD linked oxidase domain protein
HHJ44_RS01780	COG0247	lactate metabolic process
HHJ44_RS01785	COG2050	protein possibly involved in aromatic compounds catabolism
HHJ44_RS01795	COG0316	Belongs to the HesB IscA family
HHJ44_RS01800	COG0719	Fe-S assembly protein
HHJ44_RS01805	COG0396	ATPase activity
HHJ44_RS01810	COG0719	Fe-S assembly protein
HHJ44_RS01825	COG1376	ErfK ybiS ycfS ynhG family protein
HHJ44_RS01830	COG4238	major outer membrane lipoprotein
HHJ44_RS01835	COG0469	pyruvate kinase activity
HHJ44_RS01845	COG0437	4 iron, 4 sulfur cluster binding
HHJ44_RS01850	COG2414	aldehyde ferredoxin oxidoreductase
HHJ44_RS01860	COG0437	4 iron, 4 sulfur cluster binding
HHJ44_RS01865	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HHJ44_RS01875	COG4529	Protein conserved in bacteria
HHJ44_RS01895	COG3468	outer membrane autotransporter barrel domain protein
HHJ44_RS01905	COG0307	riboflavin synthase, alpha
HHJ44_RS01910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HHJ44_RS01915	COG2814	Major facilitator Superfamily
HHJ44_RS01920	COG0583	DNA-binding transcription factor activity
HHJ44_RS01935	COG2814	Major facilitator Superfamily
HHJ44_RS01940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HHJ44_RS01945	COG0791	NLP P60 protein
HHJ44_RS01950	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HHJ44_RS01960	COG0346	lactoylglutathione lyase activity
HHJ44_RS01965	COG1902	pentaerythritol trinitrate reductase activity
HHJ44_RS01970	COG1309	transcriptional regulator
HHJ44_RS01975	COG3313	Fe-S protein
HHJ44_RS01980	COG4989	oxidoreductase activity
HHJ44_RS01985	COG2032	superoxide dismutase activity
HHJ44_RS01990	COG1289	transmembrane transporter activity
HHJ44_RS01995	COG1566	PFAM secretion protein HlyD family protein
HHJ44_RS02010	COG3133	Outer membrane lipoprotein
HHJ44_RS02020	COG3895	Periplasmic Protein
HHJ44_RS02040	COG0625	glutathione transferase activity
HHJ44_RS02045	COG3104	oligopeptide transport
HHJ44_RS02050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHJ44_RS02060	COG4659	FMN binding
HHJ44_RS02100	COG0673	inositol 2-dehydrogenase activity
HHJ44_RS02110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HHJ44_RS02115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS02115	COG1263	PTS System
HHJ44_RS02120	COG1609	Transcriptional regulator
HHJ44_RS02125	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS02130	COG1309	transcriptional regulator
HHJ44_RS02135	COG3250	beta-galactosidase activity
HHJ44_RS02150	COG5339	Protein conserved in bacteria
HHJ44_RS02155	COG1482	cell wall glycoprotein biosynthetic process
HHJ44_RS02160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ44_RS02160	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ44_RS02165	COG0114	fumarate hydratase activity
HHJ44_RS02175	COG2205	protein histidine kinase activity
HHJ44_RS02180	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS02185	COG3136	membrane protein required for alginate biosynthesis
HHJ44_RS02195	COG0531	amino acid
HHJ44_RS02205	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HHJ44_RS02210	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HHJ44_RS02215	COG0628	permease
HHJ44_RS02230	COG3591	Belongs to the peptidase S1B family
HHJ44_RS02245	COG2814	Major facilitator Superfamily
HHJ44_RS02250	COG0583	DNA-binding transcription factor activity
HHJ44_RS02255	COG1940	carbohydrate kinase activity
HHJ44_RS02260	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HHJ44_RS02270	COG3381	protein complex oligomerization
HHJ44_RS02275	COG3302	dmso reductase anchor subunit
HHJ44_RS02280	COG0437	4 iron, 4 sulfur cluster binding
HHJ44_RS02285	COG0243	molybdopterin cofactor binding
HHJ44_RS02290	COG0243	molybdopterin cofactor binding
HHJ44_RS02305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHJ44_RS02320	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ44_RS02325	COG1063	alcohol dehydrogenase
HHJ44_RS02340	COG0246	Mannitol dehydrogenase
HHJ44_RS02350	COG1802	Transcriptional regulator
HHJ44_RS02355	COG4221	oxidoreductase activity
HHJ44_RS02360	COG0339	signal peptide processing
HHJ44_RS02365	COG3111	PFAM Bacterial OB fold (BOF) protein
HHJ44_RS02370	COG3706	GGDEF domain
HHJ44_RS02380	COG2814	Major facilitator Superfamily
HHJ44_RS02385	COG0697	spore germination
HHJ44_RS02390	COG2188	Transcriptional regulator
HHJ44_RS02400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HHJ44_RS02405	COG1447	Phosphotransferase system cellobiose-specific component IIA
HHJ44_RS02415	COG2723	6-phospho-beta-galactosidase activity
HHJ44_RS02425	COG4977	sequence-specific DNA binding
HHJ44_RS02430	COG1846	Transcriptional regulator
HHJ44_RS02450	COG0583	DNA-binding transcription factor activity
HHJ44_RS02455	COG1012	belongs to the aldehyde dehydrogenase family
HHJ44_RS02460	COG2066	Belongs to the glutaminase family
HHJ44_RS02470	COG2199	diguanylate cyclase activity
HHJ44_RS02480	COG3781	membrane
HHJ44_RS02490	COG1396	sequence-specific DNA binding
HHJ44_RS02495	COG3550	peptidyl-serine autophosphorylation
HHJ44_RS02505	COG0702	epimerase
HHJ44_RS02510	COG3539	Fimbrial protein
HHJ44_RS02520	COG3188	usher protein
HHJ44_RS02525	COG3539	Fimbrial protein
HHJ44_RS02530	COG3539	Fimbrial protein
HHJ44_RS02535	COG3539	Fimbrial protein
HHJ44_RS02540	COG0243	molybdopterin cofactor binding
HHJ44_RS02550	COG2207	Transcriptional regulator
HHJ44_RS02555	COG3119	arylsulfatase activity
HHJ44_RS02560	COG0641	radical SAM
HHJ44_RS02570	COG4178	(ABC) transporter
HHJ44_RS02575	COG4771	TonB-dependent receptor
HHJ44_RS02580	COG0612	Peptidase, M16
HHJ44_RS02585	COG0076	glutamate decarboxylase activity
HHJ44_RS02590	COG0531	amino acid
HHJ44_RS02600	COG3706	GGDEF domain
HHJ44_RS02600	COG3706	GGDEF domain
HHJ44_RS02605	COG2200	EAL domain
HHJ44_RS02605	COG2202	Pas domain
HHJ44_RS02605	COG2199	diguanylate cyclase activity
HHJ44_RS02610	COG1764	response to oxidative stress
HHJ44_RS02630	COG1064	alcohol dehydrogenase
HHJ44_RS02640	COG3093	addiction module antidote protein HigA
HHJ44_RS02645	COG2864	formate dehydrogenase
HHJ44_RS02650	COG0437	4 iron, 4 sulfur cluster binding
HHJ44_RS02660	COG0697	spore germination
HHJ44_RS02665	COG2223	nitrite transmembrane transporter activity
HHJ44_RS02670	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHJ44_RS02675	COG1140	nitrate reductase beta subunit
HHJ44_RS02680	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HHJ44_RS02685	COG2181	nitrate reductase activity
HHJ44_RS02690	COG0384	phenazine biosynthesis protein PhzF
HHJ44_RS02695	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HHJ44_RS02700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHJ44_RS02745	COG0625	glutathione transferase activity
HHJ44_RS02750	COG0625	glutathione transferase activity
HHJ44_RS02755	COG1113	amino acid transport
HHJ44_RS02765	COG4772	TonB-dependent receptor
HHJ44_RS02780	COG1247	-acetyltransferase
HHJ44_RS02785	COG3238	Protein conserved in bacteria
HHJ44_RS02810	COG1177	transmembrane transport
HHJ44_RS02815	COG1176	ABC-type spermidine putrescine transport system, permease component I
HHJ44_RS02820	COG3842	ATPase activity
HHJ44_RS02825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HHJ44_RS02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HHJ44_RS02845	COG0826	peptidase U32
HHJ44_RS02850	COG1396	sequence-specific DNA binding
HHJ44_RS02855	COG3135	benzoate transporter
HHJ44_RS02865	COG0500	methyltransferase
HHJ44_RS02870	COG1275	C4-dicarboxylate transporter malic acid transport protein
HHJ44_RS02875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HHJ44_RS02880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHJ44_RS02885	COG2841	Protein conserved in bacteria
HHJ44_RS02895	COG5383	Protein conserved in bacteria
HHJ44_RS02900	COG0583	DNA-binding transcription factor activity
HHJ44_RS02920	COG3038	cytochrome b561
HHJ44_RS02925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HHJ44_RS02930	COG1012	belongs to the aldehyde dehydrogenase family
HHJ44_RS02935	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HHJ44_RS02940	COG1643	Atp-dependent helicase
HHJ44_RS02950	COG2453	phosphatase
HHJ44_RS02950	COG0671	phosphoesterase, PA-phosphatase related
HHJ44_RS02955	COG2267	carboxylic ester hydrolase activity
HHJ44_RS02960	COG4589	Belongs to the CDS family
HHJ44_RS02965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHJ44_RS02970	COG0667	Aldo Keto reductase
HHJ44_RS02980	COG3784	Protein of unknown function (DUF1318)
HHJ44_RS02990	COG2911	Protein conserved in bacteria
HHJ44_RS02995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHJ44_RS03000	COG3187	Heat shock protein
HHJ44_RS03005	COG3042	response to heat
HHJ44_RS03010	COG1013	pyruvate-flavodoxin oxidoreductase activity
HHJ44_RS03010	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HHJ44_RS03010	COG0674	pyruvate-flavodoxin oxidoreductase activity
HHJ44_RS03010	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HHJ44_RS03015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHJ44_RS03020	COG0589	response to stress
HHJ44_RS03045	COG0513	Belongs to the DEAD box helicase family
HHJ44_RS03060	COG3706	GGDEF domain
HHJ44_RS03065	COG2840	Smr protein MutS2
HHJ44_RS03080	COG2207	Transcriptional regulator
HHJ44_RS03090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHJ44_RS03095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HHJ44_RS03100	COG0589	response to stress
HHJ44_RS03105	COG3182	Iron-regulated membrane protein
HHJ44_RS03110	COG0668	transmembrane transport
HHJ44_RS03115	COG4166	transmembrane transport
HHJ44_RS03120	COG0583	DNA-binding transcription factor activity
HHJ44_RS03125	COG1073	alpha beta
HHJ44_RS03135	COG0702	epimerase
HHJ44_RS03140	COG2866	Carboxypeptidase
HHJ44_RS03145	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ44_RS03150	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHJ44_RS03155	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HHJ44_RS03165	COG3106	COG3106 Predicted ATPase
HHJ44_RS03170	COG1609	Transcriptional regulator
HHJ44_RS03185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HHJ44_RS03190	COG1554	hydrolase, family 65, central catalytic
HHJ44_RS03195	COG0673	inositol 2-dehydrogenase activity
HHJ44_RS03200	COG1082	Xylose isomerase domain protein TIM barrel
HHJ44_RS03205	COG1063	alcohol dehydrogenase
HHJ44_RS03210	COG0395	ABC-type sugar transport system, permease component
HHJ44_RS03215	COG1175	transmembrane transport
HHJ44_RS03220	COG1653	transport
HHJ44_RS03225	COG0366	Alpha amylase catalytic
HHJ44_RS03230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHJ44_RS03240	COG1983	PspC domain protein
HHJ44_RS03250	COG1842	Phage shock protein A
HHJ44_RS03255	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HHJ44_RS03270	COG4166	transmembrane transport
HHJ44_RS03275	COG4168	peptide transport system, permease
HHJ44_RS03280	COG4171	peptide transport system, permease
HHJ44_RS03285	COG4172	Belongs to the ABC transporter superfamily
HHJ44_RS03290	COG4172	Belongs to the ABC transporter superfamily
HHJ44_RS03295	COG2814	Major facilitator Superfamily
HHJ44_RS03305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ44_RS03310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ44_RS03320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HHJ44_RS03325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHJ44_RS03325	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHJ44_RS03340	COG5001	Diguanylate cyclase
HHJ44_RS03350	COG1349	DNA-binding transcription factor activity
HHJ44_RS03360	COG0023	Translation Initiation Factor
HHJ44_RS03370	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HHJ44_RS03375	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HHJ44_RS03380	COG0671	phosphoesterase, PA-phosphatase related
HHJ44_RS03390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHJ44_RS03410	COG0583	DNA-binding transcription factor activity
HHJ44_RS03415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHJ44_RS03425	COG0616	signal peptide processing
HHJ44_RS03430	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS03435	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HHJ44_RS03440	COG1187	pseudouridine synthase activity
HHJ44_RS03445	COG4907	membrane protein (DUF2207)
HHJ44_RS03450	COG0009	L-threonylcarbamoyladenylate synthase
HHJ44_RS03455	COG0613	PHP domain protein
HHJ44_RS03465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHJ44_RS03470	COG0512	Glutamine amidotransferase of anthranilate synthase
HHJ44_RS03470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHJ44_RS03475	COG0135	phosphoribosylanthranilate isomerase activity
HHJ44_RS03475	COG0134	indole-3-glycerol-phosphate synthase activity
HHJ44_RS03490	COG3729	General stress protein
HHJ44_RS03495	COG3685	Protein conserved in bacteria
HHJ44_RS03500	COG3685	Protein conserved in bacteria
HHJ44_RS03520	COG0500	methyltransferase
HHJ44_RS03525	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HHJ44_RS03530	COG5301	cellulose 1,4-beta-cellobiosidase activity
HHJ44_RS03650	COG4220	transposase activity
HHJ44_RS03655	COG5562	phage envelope protein
HHJ44_RS03665	COG3772	lysozyme
HHJ44_RS03715	COG0484	heat shock protein binding
HHJ44_RS03720	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HHJ44_RS03725	COG1403	HNH endonuclease
HHJ44_RS03805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HHJ44_RS03815	COG0582	viral genome integration into host DNA
HHJ44_RS03820	COG3047	cAMP biosynthetic process
HHJ44_RS03840	COG1607	acyl-coa hydrolase
HHJ44_RS03850	COG2350	Protein conserved in bacteria
HHJ44_RS03855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HHJ44_RS03875	COG4608	Belongs to the ABC transporter superfamily
HHJ44_RS03880	COG0444	Belongs to the ABC transporter superfamily
HHJ44_RS03885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHJ44_RS03890	COG0601	transmembrane transport
HHJ44_RS03895	COG4166	transmembrane transport
HHJ44_RS03905	COG2095	MarC family integral membrane protein
HHJ44_RS03910	COG1012	belongs to the aldehyde dehydrogenase family
HHJ44_RS03910	COG1454	alcohol dehydrogenase
HHJ44_RS03920	COG1435	thymidine kinase activity
HHJ44_RS03930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HHJ44_RS03935	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS03940	COG1752	Esterase of the alpha-beta hydrolase superfamily
HHJ44_RS03950	COG0788	formyltetrahydrofolate deformylase activity
HHJ44_RS03975	COG2181	nitrate reductase activity
HHJ44_RS03980	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HHJ44_RS03985	COG1140	nitrate reductase beta subunit
HHJ44_RS03990	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHJ44_RS03995	COG2223	nitrite transmembrane transporter activity
HHJ44_RS04000	COG3850	Histidine kinase
HHJ44_RS04005	COG2197	response regulator
HHJ44_RS04010	COG4932	domain protein
HHJ44_RS04015	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HHJ44_RS04020	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HHJ44_RS04025	COG4572	Cation transport regulator
HHJ44_RS04030	COG0387	Pfam Sodium calcium exchanger
HHJ44_RS04045	COG2912	Transglutaminase-like superfamily
HHJ44_RS04050	COG3094	Invasion gene expression up-regulator, SirB
HHJ44_RS04055	COG2890	protein-(glutamine-N5) methyltransferase activity
HHJ44_RS04080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHJ44_RS04085	COG0659	secondary active sulfate transmembrane transporter activity
HHJ44_RS04100	COG0012	GTP binding
HHJ44_RS04110	COG3284	Transcriptional regulator
HHJ44_RS04115	COG2376	Dihydroxyacetone kinase
HHJ44_RS04120	COG1461	Dihydroxyacetone kinase
HHJ44_RS04125	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HHJ44_RS04125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHJ44_RS04125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS04145	COG1120	ATPase activity
HHJ44_RS04150	COG0500	methyltransferase
HHJ44_RS04155	COG0157	Belongs to the NadC ModD family
HHJ44_RS04170	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HHJ44_RS04180	COG1619	proteins homologs of microcin C7 resistance protein MccF
HHJ44_RS04190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHJ44_RS04200	COG2719	SpoVR family
HHJ44_RS04220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHJ44_RS04225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHJ44_RS04240	COG0179	Fumarylacetoacetate (FAA) hydrolase
HHJ44_RS04265	COG2894	cell division
HHJ44_RS04340	COG2200	EAL domain
HHJ44_RS04345	COG0789	Transcriptional regulator
HHJ44_RS04350	COG5562	phage envelope protein
HHJ44_RS04360	COG0538	isocitrate dehydrogenase activity
HHJ44_RS04430	COG1196	nuclear chromosome segregation
HHJ44_RS04500	COG4220	transposase activity
HHJ44_RS04715	COG0582	viral genome integration into host DNA
HHJ44_RS04720	COG0538	isocitrate dehydrogenase activity
HHJ44_RS04725	COG1187	pseudouridine synthase activity
HHJ44_RS04745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHJ44_RS04755	COG2205	protein histidine kinase activity
HHJ44_RS04760	COG2850	peptidyl-arginine hydroxylation
HHJ44_RS04780	COG1177	transmembrane transport
HHJ44_RS04785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HHJ44_RS04795	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HHJ44_RS04800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHJ44_RS04810	COG4591	ABC-type transport system involved in lipoprotein release permease component
HHJ44_RS04820	COG4591	ABC-type transport system involved in lipoprotein release permease component
HHJ44_RS04825	COG4763	Acyl-transferase
HHJ44_RS04830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHJ44_RS04835	COG1388	LysM domain
HHJ44_RS04835	COG1376	ErfK ybiS ycfS ynhG family protein
HHJ44_RS04845	COG1309	transcriptional regulator
HHJ44_RS04850	COG3134	Outer membrane lipoprotein
HHJ44_RS04855	COG1252	NADH dehydrogenase
HHJ44_RS04875	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HHJ44_RS04880	COG5633	Lipoprotein
HHJ44_RS04885	COG0537	adenosine 5'-monophosphoramidase activity
HHJ44_RS04890	COG4773	Receptor
HHJ44_RS04895	COG1263	PTS System
HHJ44_RS04895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS04900	COG0084	hydrolase, TatD family'
HHJ44_RS04905	COG0470	DNA polymerase III
HHJ44_RS04915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHJ44_RS04920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HHJ44_RS04925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HHJ44_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS04940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HHJ44_RS04960	COG1399	metal-binding, possibly nucleic acid-binding protein
HHJ44_RS04965	COG0424	maF-like protein
HHJ44_RS04970	COG0564	pseudouridine synthase activity
HHJ44_RS04975	COG1530	ribonuclease E activity
HHJ44_RS04980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHJ44_RS04985	COG1256	bacterial-type flagellum assembly
HHJ44_RS04990	COG1705	Flagellar rod assembly protein muramidase FlgJ
HHJ44_RS04990	COG3951	Flagellar rod assembly protein muramidase FlgJ
HHJ44_RS05005	COG4786	Flagellar basal body rod
HHJ44_RS05010	COG4787	bacterial-type flagellum-dependent cell motility
HHJ44_RS05015	COG1749	Flagellar hook protein flgE
HHJ44_RS05020	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HHJ44_RS05025	COG1558	bacterial-type flagellum-dependent cell motility
HHJ44_RS05030	COG1815	bacterial-type flagellum-dependent cell motility
HHJ44_RS05035	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HHJ44_RS05040	COG2747	anti-sigma28 factor FlgM
HHJ44_RS05045	COG3418	PFAM FlgN family protein
HHJ44_RS05050	COG0728	peptidoglycan biosynthetic process
HHJ44_RS05055	COG0673	inositol 2-dehydrogenase activity
HHJ44_RS05065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHJ44_RS05075	COG2999	glutathione oxidoreductase activity
HHJ44_RS05110	COG3038	cytochrome b561
HHJ44_RS05115	COG2353	YceI-like domain
HHJ44_RS05125	COG1560	Kdo2-lipid A biosynthetic process
HHJ44_RS05140	COG5645	(Lipo)protein
HHJ44_RS05145	COG2943	transferase activity, transferring hexosyl groups
HHJ44_RS05160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHJ44_RS05165	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HHJ44_RS05190	COG2197	response regulator
HHJ44_RS05205	COG1462	curli production assembly transport component CsgG
HHJ44_RS05215	COG3381	protein complex oligomerization
HHJ44_RS05235	COG3706	GGDEF domain
HHJ44_RS05240	COG0457	Tetratricopeptide repeat
HHJ44_RS05245	COG1649	PFAM Uncharacterised BCR, COG1649
HHJ44_RS05245	COG0726	polysaccharide deacetylase
HHJ44_RS05250	COG1215	transferase activity, transferring glycosyl groups
HHJ44_RS05255	COG3658	cytochrome
HHJ44_RS05260	COG1702	phosphate starvation-inducible protein PhoH
HHJ44_RS05280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHJ44_RS05290	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HHJ44_RS05290	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HHJ44_RS05290	COG0506	proline dehydrogenase activity
HHJ44_RS05295	COG1309	transcriptional regulator
HHJ44_RS05335	COG3729	General stress protein
HHJ44_RS05370	COG0243	molybdopterin cofactor binding
HHJ44_RS05375	COG3005	denitrification pathway
HHJ44_RS05380	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS05385	COG1879	ABC-type sugar transport system periplasmic component
HHJ44_RS05390	COG2205	protein histidine kinase activity
HHJ44_RS05390	COG2198	Histidine kinase
HHJ44_RS05390	COG0784	Response regulator, receiver
HHJ44_RS05395	COG0348	domain, Protein
HHJ44_RS05415	COG1278	Cold shock
HHJ44_RS05420	COG1278	Cold shock
HHJ44_RS05435	COG1294	oxidase, subunit
HHJ44_RS05440	COG1271	oxidase subunit
HHJ44_RS05445	COG1773	rubredoxin
HHJ44_RS05450	COG1999	signal sequence binding
HHJ44_RS05455	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHJ44_RS05460	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HHJ44_RS05465	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HHJ44_RS05470	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HHJ44_RS05480	COG0670	Belongs to the BI1 family
HHJ44_RS05485	COG2920	part of a sulfur-relay system
HHJ44_RS05505	COG1832	CoA-binding protein
HHJ44_RS05520	COG0210	DNA helicase
HHJ44_RS05525	COG3304	Inner membrane component domain
HHJ44_RS05530	COG1289	transmembrane transporter activity
HHJ44_RS05535	COG3070	regulator of competence-specific genes
HHJ44_RS05545	COG2885	chlorophyll binding
HHJ44_RS05545	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HHJ44_RS05555	COG1067	ATP-dependent peptidase activity
HHJ44_RS05565	COG3130	regulation of translation
HHJ44_RS05570	COG3009	Protein conserved in bacteria
HHJ44_RS05575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HHJ44_RS05575	COG3008	intermembrane lipid transfer
HHJ44_RS05580	COG2995	paraquat-inducible protein a
HHJ44_RS05585	COG0488	(ABC) transporter
HHJ44_RS05595	COG0633	Ferredoxin
HHJ44_RS05595	COG3217	Mosc domain protein beta barrel domain protein
HHJ44_RS05610	COG0431	NADPH-dependent FMN reductase
HHJ44_RS05615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HHJ44_RS05625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HHJ44_RS05635	COG0308	aminopeptidase N
HHJ44_RS05655	COG1448	Aminotransferase
HHJ44_RS05660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HHJ44_RS05665	COG3108	Peptidase M15
HHJ44_RS05670	COG2989	Protein conserved in bacteria
HHJ44_RS05680	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HHJ44_RS05690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HHJ44_RS05695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HHJ44_RS05700	COG3173	Aminoglycoside phosphotransferase
HHJ44_RS05715	COG3214	Protein conserved in bacteria
HHJ44_RS05730	COG2333	competence protein COMEC
HHJ44_RS05730	COG0658	competence protein
HHJ44_RS05740	COG0539	negative regulation of cytoplasmic translation
HHJ44_RS05750	COG0501	Belongs to the peptidase M48B family
HHJ44_RS05765	COG2323	membrane
HHJ44_RS05770	COG1944	ATP diphosphatase activity
HHJ44_RS05775	COG2116	formate transmembrane transporter activity
HHJ44_RS05780	COG1882	Formate acetyltransferase
HHJ44_RS05785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHJ44_RS05795	COG1335	isochorismatase
HHJ44_RS05800	COG3302	dmso reductase anchor subunit
HHJ44_RS05805	COG0437	4 iron, 4 sulfur cluster binding
HHJ44_RS05810	COG0243	molybdopterin cofactor binding
HHJ44_RS05820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HHJ44_RS05830	COG1674	ftsk spoiiie
HHJ44_RS05830	COG1178	ABC-type Fe3 transport system permease component
HHJ44_RS05835	COG1522	sequence-specific DNA binding
HHJ44_RS05840	COG0492	ferredoxin-NADP+ reductase activity
HHJ44_RS05845	COG4988	ABC transporter
HHJ44_RS05850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HHJ44_RS05890	COG1203	CRISPR-associated helicase, Cas3
HHJ44_RS05895	COG1518	maintenance of DNA repeat elements
HHJ44_RS05900	COG0542	response to heat
HHJ44_RS05910	COG1278	Cold shock
HHJ44_RS05920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ44_RS05925	COG2990	Protein conserved in bacteria
HHJ44_RS05930	COG3593	DNA synthesis involved in DNA repair
HHJ44_RS05940	COG2431	L-lysine efflux transmembrane transporter activity
HHJ44_RS05950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHJ44_RS05955	COG0028	Belongs to the TPP enzyme family
HHJ44_RS05960	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HHJ44_RS05965	COG0702	epimerase
HHJ44_RS05970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HHJ44_RS05975	COG3023	N-Acetylmuramoyl-L-alanine amidase
HHJ44_RS05990	COG1126	abc transporter atp-binding protein
HHJ44_RS05995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ44_RS06000	COG4215	(ABC) transporter
HHJ44_RS06005	COG4160	amino acid transport
HHJ44_RS06010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ44_RS06025	COG1177	transmembrane transport
HHJ44_RS06030	COG1176	ABC-type spermidine putrescine transport system, permease component I
HHJ44_RS06035	COG3842	ATPase activity
HHJ44_RS06040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HHJ44_RS06055	COG0778	Nitroreductase
HHJ44_RS06065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HHJ44_RS06120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HHJ44_RS06130	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HHJ44_RS06225	COG4695	Portal protein
HHJ44_RS06260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HHJ44_RS06300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HHJ44_RS06310	COG2197	response regulator
HHJ44_RS06335	COG1376	ErfK ybiS ycfS ynhG family protein
HHJ44_RS06350	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HHJ44_RS06355	COG4771	TonB-dependent receptor
HHJ44_RS06360	COG1475	DNA binding
HHJ44_RS06365	COG3969	phosphoadenosine phosphosulfate
HHJ44_RS06370	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HHJ44_RS06375	COG1215	transferase activity, transferring glycosyl groups
HHJ44_RS06390	COG3547	Transposase (IS116 IS110 IS902 family)
HHJ44_RS06400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS06415	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HHJ44_RS06450	COG3547	Transposase (IS116 IS110 IS902 family)
HHJ44_RS06500	COG1120	ATPase activity
HHJ44_RS06505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ44_RS06560	COG2003	Belongs to the UPF0758 family
HHJ44_RS06605	COG1289	transmembrane transporter activity
HHJ44_RS06615	COG1686	Belongs to the peptidase S11 family
HHJ44_RS06620	COG2925	Exonuclease
HHJ44_RS06625	COG0531	amino acid
HHJ44_RS06635	COG0583	DNA-binding transcription factor activity
HHJ44_RS06640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HHJ44_RS06645	COG4115	mRNA cleavage
HHJ44_RS06650	COG2161	toxin-antitoxin pair type II binding
HHJ44_RS06665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHJ44_RS06675	COG0131	Imidazoleglycerol-phosphate dehydratase
HHJ44_RS06675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HHJ44_RS06680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHJ44_RS06695	COG0140	phosphoribosyl-ATP diphosphatase activity
HHJ44_RS06695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HHJ44_RS06700	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HHJ44_RS06705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHJ44_RS06710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHJ44_RS06755	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHJ44_RS06760	COG1091	dTDP-4-dehydrorhamnose reductase activity
HHJ44_RS06765	COG1088	dTDP-glucose 4,6-dehydratase activity
HHJ44_RS06770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HHJ44_RS06780	COG0438	transferase activity, transferring glycosyl groups
HHJ44_RS06785	COG2327	Polysaccharide pyruvyl transferase
HHJ44_RS06790	COG2244	polysaccharide biosynthetic process
HHJ44_RS06795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HHJ44_RS06800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHJ44_RS06805	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HHJ44_RS06805	COG0662	Cupin 2, conserved barrel domain protein
HHJ44_RS06810	COG0297	glycogen (starch) synthase activity
HHJ44_RS06815	COG1051	belongs to the nudix hydrolase family
HHJ44_RS06820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HHJ44_RS06825	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HHJ44_RS06830	COG0110	maltose O-acetyltransferase activity
HHJ44_RS06835	COG1216	Glycosyl transferase, family 2
HHJ44_RS06845	COG0438	transferase activity, transferring glycosyl groups
HHJ44_RS06850	COG1045	serine acetyltransferase
HHJ44_RS06855	COG0463	Glycosyl transferase, family 2
HHJ44_RS06860	COG3206	protein involved in exopolysaccharide biosynthesis
HHJ44_RS06860	COG0489	protein tyrosine kinase activity
HHJ44_RS06865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHJ44_RS06870	COG1596	polysaccharide export
HHJ44_RS06880	COG1253	flavin adenine dinucleotide binding
HHJ44_RS06895	COG2982	Protein involved in outer membrane biogenesis
HHJ44_RS06905	COG0572	uridine kinase
HHJ44_RS06910	COG5002	protein histidine kinase activity
HHJ44_RS06910	COG3447	MASE1 domain protein
HHJ44_RS06910	COG5001	Diguanylate cyclase
HHJ44_RS06915	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HHJ44_RS06920	COG0443	Heat shock 70 kDa protein
HHJ44_RS06925	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
HHJ44_RS06930	COG0631	protein serine/threonine phosphatase activity
HHJ44_RS06935	COG4245	von Willebrand factor, type A
HHJ44_RS06970	COG2205	protein histidine kinase activity
HHJ44_RS06975	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS06980	COG3422	double-strand break repair
HHJ44_RS07025	COG1063	alcohol dehydrogenase
HHJ44_RS07030	COG3775	system Galactitol-specific IIC component
HHJ44_RS07035	COG3414	Phosphotransferase system galactitol-specific IIB component
HHJ44_RS07040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS07055	COG1830	Aldolase
HHJ44_RS07060	COG2211	Major facilitator Superfamily
HHJ44_RS07065	COG1397	ADP-ribosylglycohydrolase
HHJ44_RS07070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS07075	COG2188	Transcriptional regulator
HHJ44_RS07080	COG3757	hydrolase, family 25
HHJ44_RS07085	COG0351	phosphomethylpyrimidine kinase
HHJ44_RS07105	COG5455	response to cobalt ion
HHJ44_RS07110	COG3539	Fimbrial protein
HHJ44_RS07115	COG3188	usher protein
HHJ44_RS07120	COG3121	Chaperone
HHJ44_RS07125	COG3539	Fimbrial protein
HHJ44_RS07135	COG0489	protein tyrosine kinase activity
HHJ44_RS07145	COG3831	ATPase activity
HHJ44_RS07150	COG3831	ATPase activity
HHJ44_RS07160	COG0714	Associated with various cellular activities
HHJ44_RS07165	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HHJ44_RS07170	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HHJ44_RS07175	COG4715	Zinc finger, swim domain protein
HHJ44_RS07180	COG4808	Protein conserved in bacteria
HHJ44_RS07185	COG4807	Protein conserved in bacteria
HHJ44_RS07190	COG3279	Response regulator of the LytR AlgR family
HHJ44_RS07195	COG3275	phosphorelay sensor kinase activity
HHJ44_RS07200	COG0789	Transcriptional regulator
HHJ44_RS07210	COG1174	glycine betaine transport
HHJ44_RS07215	COG1125	glycine betaine transport
HHJ44_RS07220	COG1174	glycine betaine transport
HHJ44_RS07225	COG1732	Glycine betaine
HHJ44_RS07230	COG1472	Belongs to the glycosyl hydrolase 3 family
HHJ44_RS07235	COG0277	FAD linked oxidase domain protein
HHJ44_RS07240	COG1686	Belongs to the peptidase S11 family
HHJ44_RS07250	COG0586	Pfam SNARE associated Golgi protein
HHJ44_RS07255	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS07260	COG1538	Outer membrane efflux protein
HHJ44_RS07270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHJ44_RS07280	COG1346	cytolysis
HHJ44_RS07290	COG2949	membrane
HHJ44_RS07300	COG0493	'glutamate synthase
HHJ44_RS07305	COG0167	dihydroorotate dehydrogenase activity
HHJ44_RS07305	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HHJ44_RS07310	COG4211	Belongs to the binding-protein-dependent transport system permease family
HHJ44_RS07320	COG1879	ABC-type sugar transport system periplasmic component
HHJ44_RS07325	COG1609	Transcriptional regulator
HHJ44_RS07330	COG2311	Membrane
HHJ44_RS07345	COG4771	TonB-dependent receptor
HHJ44_RS07350	COG0833	amino acid
HHJ44_RS07355	COG0583	DNA-binding transcription factor activity
HHJ44_RS07360	COG2855	membrane
HHJ44_RS07370	COG1522	sequence-specific DNA binding
HHJ44_RS07370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS07380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HHJ44_RS07385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHJ44_RS07390	COG2313	pseudouridylate synthase activity
HHJ44_RS07395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS07400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS07400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS07400	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HHJ44_RS07405	COG1105	Belongs to the carbohydrate kinase PfkB family
HHJ44_RS07410	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS07410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS07415	COG2814	Major facilitator Superfamily
HHJ44_RS07430	COG0246	Mannitol dehydrogenase
HHJ44_RS07435	COG0523	cobalamin synthesis protein
HHJ44_RS07440	COG0671	phosphoesterase, PA-phosphatase related
HHJ44_RS07445	COG0791	NLP P60 protein
HHJ44_RS07450	COG2200	EAL domain
HHJ44_RS07455	COG4166	transmembrane transport
HHJ44_RS07460	COG4174	ABC transporter (Permease)
HHJ44_RS07465	COG4239	(ABC) transporter, permease
HHJ44_RS07470	COG4172	Belongs to the ABC transporter superfamily
HHJ44_RS07480	COG2814	Major facilitator Superfamily
HHJ44_RS07485	COG1187	pseudouridine synthase activity
HHJ44_RS07490	COG1061	Type III restriction enzyme res subunit
HHJ44_RS07510	COG3083	sulfuric ester hydrolase activity
HHJ44_RS07520	COG3468	outer membrane autotransporter barrel domain protein
HHJ44_RS07525	COG3468	outer membrane autotransporter barrel domain protein
HHJ44_RS07530	COG2197	response regulator
HHJ44_RS07535	COG3088	subunit of a heme lyase
HHJ44_RS07535	COG4235	cytochrome complex assembly
HHJ44_RS07540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HHJ44_RS07545	COG1138	Cytochrome C-type biogenesis protein
HHJ44_RS07555	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HHJ44_RS07560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HHJ44_RS07565	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HHJ44_RS07575	COG3005	denitrification pathway
HHJ44_RS07580	COG3043	anaerobic respiration
HHJ44_RS07585	COG0348	domain, Protein
HHJ44_RS07590	COG0437	4 iron, 4 sulfur cluster binding
HHJ44_RS07600	COG3062	negative regulation of establishment of protein localization
HHJ44_RS07605	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ44_RS07605	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ44_RS07625	COG4615	Cyclic peptide transporter
HHJ44_RS07630	COG3145	DNA-N1-methyladenine dioxygenase activity
HHJ44_RS07635	COG2169	Transcriptional regulator
HHJ44_RS07635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHJ44_RS07640	COG1477	protein flavinylation
HHJ44_RS07645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHJ44_RS07650	COG2198	Histidine kinase
HHJ44_RS07650	COG0642	Histidine kinase
HHJ44_RS07655	COG2197	response regulator
HHJ44_RS07660	COG0784	Response regulator, receiver
HHJ44_RS07660	COG2205	protein histidine kinase activity
HHJ44_RS07665	COG3852	Histidine kinase
HHJ44_RS07670	COG2204	response regulator
HHJ44_RS07675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HHJ44_RS07680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HHJ44_RS07685	COG2031	fatty acid transporter
HHJ44_RS07690	COG0183	Belongs to the thiolase family
HHJ44_RS07695	COG4676	Protein conserved in bacteria
HHJ44_RS07700	COG5445	Predicted secreted protein (DUF2300)
HHJ44_RS07705	COG2373	Large extracellular alpha-helical protein
HHJ44_RS07715	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HHJ44_RS07720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHJ44_RS07730	COG3468	outer membrane autotransporter barrel domain protein
HHJ44_RS07735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHJ44_RS07740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHJ44_RS07745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHJ44_RS07750	COG3642	lipopolysaccharide core region biosynthetic process
HHJ44_RS07755	COG0584	glycerophosphoryl diester phosphodiesterase
HHJ44_RS07760	COG2271	Major facilitator Superfamily
HHJ44_RS07765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HHJ44_RS07775	COG0247	lactate metabolic process
HHJ44_RS07780	COG5464	transposase or invertase
HHJ44_RS07795	COG2271	Major facilitator Superfamily
HHJ44_RS07805	COG1414	Transcriptional regulator
HHJ44_RS07870	COG0318	PFAM AMP-dependent synthetase and ligase
HHJ44_RS07880	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HHJ44_RS07895	COG1169	isochorismate synthase
HHJ44_RS07900	COG4575	ribosome binding
HHJ44_RS07905	COG2153	protein acetylation
HHJ44_RS07915	COG2304	oxidoreductase activity
HHJ44_RS07920	COG2234	aminopeptidase activity
HHJ44_RS07935	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HHJ44_RS07940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HHJ44_RS07950	COG0839	Belongs to the complex I subunit 6 family
HHJ44_RS07965	COG1034	ATP synthesis coupled electron transport
HHJ44_RS07970	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HHJ44_RS07975	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HHJ44_RS07995	COG0583	DNA-binding transcription factor activity
HHJ44_RS08000	COG0436	Aminotransferase
HHJ44_RS08010	COG0490	domain, Protein
HHJ44_RS08010	COG0471	metal ion transport
HHJ44_RS08015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HHJ44_RS08030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHJ44_RS08035	COG0280	phosphate acetyltransferase
HHJ44_RS08035	COG0857	belongs to the CobB CobQ family
HHJ44_RS08040	COG1288	antiporter activity
HHJ44_RS08045	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HHJ44_RS08050	COG0622	Phosphoesterase
HHJ44_RS08055	COG0625	glutathione transferase activity
HHJ44_RS08060	COG0625	glutathione transferase activity
HHJ44_RS08065	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHJ44_RS08070	COG1090	epimerase
HHJ44_RS08075	COG5464	transposase or invertase
HHJ44_RS08080	COG4598	ABC transporter
HHJ44_RS08085	COG4160	amino acid transport
HHJ44_RS08090	COG4215	(ABC) transporter
HHJ44_RS08095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ44_RS08100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ44_RS08105	COG0163	prenyltransferase activity
HHJ44_RS08110	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHJ44_RS08115	COG1286	toxin biosynthetic process
HHJ44_RS08120	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HHJ44_RS08125	COG0285	dihydrofolate synthase activity
HHJ44_RS08135	COG0586	Pfam SNARE associated Golgi protein
HHJ44_RS08145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHJ44_RS08160	COG2814	Major facilitator Superfamily
HHJ44_RS08165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HHJ44_RS08180	COG3101	peptidyl-lysine hydroxylation
HHJ44_RS08185	COG0730	response to heat
HHJ44_RS08215	COG3539	Fimbrial protein
HHJ44_RS08220	COG3539	Fimbrial protein
HHJ44_RS08225	COG3539	Fimbrial protein
HHJ44_RS08230	COG3121	Chaperone
HHJ44_RS08235	COG3188	usher protein
HHJ44_RS08245	COG2062	phosphohistidine phosphatase, SixA
HHJ44_RS08260	COG3691	Protein conserved in bacteria
HHJ44_RS08265	COG2067	long-chain fatty acid transport protein
HHJ44_RS08275	COG2116	formate transmembrane transporter activity
HHJ44_RS08285	COG0583	DNA-binding transcription factor activity
HHJ44_RS08290	COG2610	gluconate transmembrane transporter activity
HHJ44_RS08300	COG0477	Major facilitator Superfamily
HHJ44_RS08305	COG1566	PFAM secretion protein HlyD family protein
HHJ44_RS08310	COG2197	response regulator
HHJ44_RS08315	COG0784	Response regulator, receiver
HHJ44_RS08315	COG2205	protein histidine kinase activity
HHJ44_RS08315	COG2198	Histidine kinase
HHJ44_RS08315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ44_RS08320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HHJ44_RS08325	COG0679	Auxin Efflux Carrier
HHJ44_RS08330	COG0028	Belongs to the TPP enzyme family
HHJ44_RS08355	COG1560	Kdo2-lipid A biosynthetic process
HHJ44_RS08365	COG0436	Aminotransferase
HHJ44_RS08370	COG3275	phosphorelay sensor kinase activity
HHJ44_RS08375	COG3279	Response regulator of the LytR AlgR family
HHJ44_RS08380	COG2207	Transcriptional regulator
HHJ44_RS08385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHJ44_RS08385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS08385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS08390	COG1363	Peptidase, m42
HHJ44_RS08395	COG0006	proline dipeptidase activity
HHJ44_RS08400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS08405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS08430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHJ44_RS08435	COG2200	EAL domain
HHJ44_RS08435	COG2199	diguanylate cyclase activity
HHJ44_RS08450	COG3415	Transposase
HHJ44_RS08455	COG3415	Transposase
HHJ44_RS08485	COG0583	DNA-binding transcription factor activity
HHJ44_RS08495	COG2211	Major facilitator Superfamily
HHJ44_RS08500	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HHJ44_RS08510	COG0583	DNA-binding transcription factor activity
HHJ44_RS08515	COG0385	Bile acid
HHJ44_RS08520	COG3530	Putative quorum-sensing-regulated virulence factor
HHJ44_RS08540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HHJ44_RS08545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS08550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHJ44_RS08555	COG2190	(PTS) system
HHJ44_RS08570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HHJ44_RS08575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HHJ44_RS08580	COG4208	sulfate ABC transporter
HHJ44_RS08585	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HHJ44_RS08590	COG4150	thiosulfate binding
HHJ44_RS08595	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS08610	COG2837	iron assimilation
HHJ44_RS08630	COG0860	N-Acetylmuramoyl-L-alanine amidase
HHJ44_RS08640	COG2207	Transcriptional regulator
HHJ44_RS08645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HHJ44_RS08650	COG4816	utilization protein
HHJ44_RS08660	COG4303	Ethanolamine ammonia lyase large subunit
HHJ44_RS08665	COG4819	ethanolamine utilization protein
HHJ44_RS08670	COG3192	ethanolamine utilization protein
HHJ44_RS08675	COG1454	alcohol dehydrogenase
HHJ44_RS08680	COG4820	ethanolamine utilization protein (EutJ)
HHJ44_RS08685	COG1012	belongs to the aldehyde dehydrogenase family
HHJ44_RS08690	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HHJ44_RS08695	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HHJ44_RS08700	COG0280	phosphate acetyltransferase
HHJ44_RS08705	COG4812	Cobalamin adenosyltransferase
HHJ44_RS08710	COG4766	ethanolamine catabolic process
HHJ44_RS08715	COG4917	ethanolamine utilization protein
HHJ44_RS08720	COG4810	utilization protein
HHJ44_RS08725	COG0280	phosphate acetyltransferase
HHJ44_RS08725	COG0281	malic enzyme
HHJ44_RS08730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHJ44_RS08735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHJ44_RS08740	COG5342	invasion associated locus B
HHJ44_RS08750	COG0493	'glutamate synthase
HHJ44_RS08750	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ44_RS08755	COG3850	Histidine kinase
HHJ44_RS08760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ44_RS08770	COG1393	Belongs to the ArsC family
HHJ44_RS08785	COG0400	carboxylic ester hydrolase activity
HHJ44_RS08795	COG2321	neutral zinc metallopeptidase
HHJ44_RS08805	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HHJ44_RS08815	COG2716	regulation of RNA biosynthetic process
HHJ44_RS08820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHJ44_RS08825	COG0628	permease
HHJ44_RS08830	COG4783	chaperone-mediated protein folding
HHJ44_RS08835	COG1393	Belongs to the ArsC family
HHJ44_RS08845	COG2233	PERMEase
HHJ44_RS08860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHJ44_RS08865	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HHJ44_RS08870	COG0248	Ppx GppA phosphatase
HHJ44_RS08875	COG2200	EAL domain
HHJ44_RS08890	COG3133	Outer membrane lipoprotein
HHJ44_RS08905	COG0516	GMP reductase activity
HHJ44_RS08905	COG0517	IMP dehydrogenase activity
HHJ44_RS08930	COG1645	bacterial-type flagellum-dependent swarming motility
HHJ44_RS08945	COG2976	Protein conserved in bacteria
HHJ44_RS08975	COG4953	penicillin-binding protein 1C
HHJ44_RS08980	COG2373	Large extracellular alpha-helical protein
HHJ44_RS08985	COG2897	thiosulfate sulfurtransferase activity
HHJ44_RS09000	COG2975	iron-sulfur cluster assembly
HHJ44_RS09005	COG0633	Ferredoxin
HHJ44_RS09025	COG0822	iron-sulfur transferase activity
HHJ44_RS09045	COG0483	inositol monophosphate 1-phosphatase activity
HHJ44_RS09050	COG1073	alpha beta
HHJ44_RS09055	COG3711	transcriptional antiterminator
HHJ44_RS09060	COG2814	Major facilitator Superfamily
HHJ44_RS09065	COG2259	Doxx family
HHJ44_RS09070	COG2017	converts alpha-aldose to the beta-anomer
HHJ44_RS09075	COG1063	alcohol dehydrogenase
HHJ44_RS09080	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ44_RS09085	COG1129	ABC transporter
HHJ44_RS09090	COG1879	ABC-type sugar transport system periplasmic component
HHJ44_RS09095	COG0457	Tetratricopeptide repeat
HHJ44_RS09100	COG1940	carbohydrate kinase activity
HHJ44_RS09110	COG1017	nitric oxide dioxygenase activity
HHJ44_RS09110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHJ44_RS09115	COG0347	Belongs to the P(II) protein family
HHJ44_RS09120	COG2204	response regulator
HHJ44_RS09125	COG3170	Tfp pilus assembly protein FimV
HHJ44_RS09130	COG2205	protein histidine kinase activity
HHJ44_RS09145	COG0590	tRNA wobble adenosine to inosine editing
HHJ44_RS09150	COG0560	Phosphoserine phosphatase
HHJ44_RS09155	COG1737	Transcriptional regulator
HHJ44_RS09160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ44_RS09175	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HHJ44_RS09195	COG0681	Belongs to the peptidase S26 family
HHJ44_RS09205	COG3086	response to oxidative stress
HHJ44_RS09210	COG3026	antisigma factor binding
HHJ44_RS09215	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HHJ44_RS09220	COG1595	DNA-templated transcription, initiation
HHJ44_RS09230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HHJ44_RS09240	COG0513	Belongs to the DEAD box helicase family
HHJ44_RS09245	COG0583	DNA-binding transcription factor activity
HHJ44_RS09265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHJ44_RS09270	COG3118	belongs to the thioredoxin family
HHJ44_RS09280	COG1042	CoA-binding domain protein
HHJ44_RS09280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHJ44_RS09280	COG0045	succinate-CoA ligase (ADP-forming) activity
HHJ44_RS09285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHJ44_RS09295	COG5544	Lipoprotein
HHJ44_RS09300	COG0477	Major facilitator Superfamily
HHJ44_RS09335	COG0542	response to heat
HHJ44_RS09345	COG0564	pseudouridine synthase activity
HHJ44_RS09350	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ44_RS09355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHJ44_RS09365	COG0077	Prephenate dehydratase
HHJ44_RS09365	COG1605	Chorismate mutase
HHJ44_RS09370	COG0287	Prephenate dehydrogenase
HHJ44_RS09370	COG1605	Chorismate mutase
HHJ44_RS09375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHJ44_RS09390	COG2199	diguanylate cyclase activity
HHJ44_RS09395	COG2885	chlorophyll binding
HHJ44_RS09420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHJ44_RS09425	COG4137	Cytochrome C assembly protein
HHJ44_RS09430	COG4536	flavin adenine dinucleotide binding
HHJ44_RS09445	COG0497	DNA recombination
HHJ44_RS09450	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ44_RS09460	COG2867	negative regulation of translational initiation
HHJ44_RS09515	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HHJ44_RS09525	COG3778	Protein conserved in bacteria
HHJ44_RS09530	COG3299	homolog of phage Mu protein gp47
HHJ44_RS09550	COG4228	DNA circulation
HHJ44_RS09570	COG4386	tail sheath protein
HHJ44_RS09615	COG4695	Portal protein
HHJ44_RS09625	COG1802	Transcriptional regulator
HHJ44_RS09625	COG4626	Terminase
HHJ44_RS09670	COG0484	heat shock protein binding
HHJ44_RS09675	COG1403	HNH endonuclease
HHJ44_RS09685	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HHJ44_RS09695	COG4725	Belongs to the MT-A70-like family
HHJ44_RS09705	COG1846	Transcriptional regulator
HHJ44_RS09720	COG4197	protein conserved in bacteria, prophage-related
HHJ44_RS09725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHJ44_RS09745	COG5532	Uncharacterized conserved protein (DUF2303)
HHJ44_RS09760	COG0582	viral genome integration into host DNA
HHJ44_RS09785	COG0579	oxidoreductase
HHJ44_RS09790	COG1012	belongs to the aldehyde dehydrogenase family
HHJ44_RS09795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHJ44_RS09800	COG1113	amino acid transport
HHJ44_RS09805	COG1802	Transcriptional regulator
HHJ44_RS09810	COG1652	LysM domain
HHJ44_RS09815	COG0401	homolog of Blt101
HHJ44_RS09820	COG0640	Transcriptional regulator
HHJ44_RS09825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHJ44_RS09830	COG2916	Histone family protein nucleoid-structuring protein H-NS
HHJ44_RS09845	COG4575	ribosome binding
HHJ44_RS09855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHJ44_RS09860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HHJ44_RS09870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHJ44_RS09875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHJ44_RS09880	COG4175	Glycine betaine
HHJ44_RS09885	COG4176	ABC-type proline glycine betaine transport system permease component
HHJ44_RS09890	COG2113	Glycine betaine
HHJ44_RS09895	COG2814	Major facilitator Superfamily
HHJ44_RS09900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HHJ44_RS09910	COG1846	Transcriptional regulator
HHJ44_RS09915	COG1566	PFAM secretion protein HlyD family protein
HHJ44_RS09920	COG2814	Major facilitator Superfamily
HHJ44_RS09945	COG1238	metal cluster binding
HHJ44_RS09950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HHJ44_RS09975	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HHJ44_RS09995	COG1546	Belongs to the CinA family
HHJ44_RS10000	COG2951	lytic endotransglycosylase activity
HHJ44_RS10005	COG3730	PTS system glucitol sorbitol-specific
HHJ44_RS10010	COG3732	PTS system glucitol sorbitol-specific
HHJ44_RS10020	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS10025	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS10030	COG1349	DNA-binding transcription factor activity
HHJ44_RS10035	COG0517	IMP dehydrogenase activity
HHJ44_RS10035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HHJ44_RS10055	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HHJ44_RS10060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ44_RS10065	COG1609	Transcriptional regulator
HHJ44_RS10070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS10070	COG1263	PTS System
HHJ44_RS10075	COG2723	6-phospho-beta-galactosidase activity
HHJ44_RS10080	COG5499	transcription regulator containing HTH domain
HHJ44_RS10090	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHJ44_RS10100	COG3260	NADH ubiquinone oxidoreductase 20
HHJ44_RS10105	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HHJ44_RS10110	COG3261	NADH dehydrogenase
HHJ44_RS10110	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HHJ44_RS10115	COG0650	Formate hydrogenlyase subunit 4
HHJ44_RS10120	COG0651	ATP synthesis coupled electron transport
HHJ44_RS10125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ44_RS10135	COG0375	protein maturation
HHJ44_RS10140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HHJ44_RS10145	COG0298	carbon dioxide binding
HHJ44_RS10150	COG0409	Hydrogenase expression formation protein
HHJ44_RS10155	COG0309	Hydrogenase expression formation protein (HypE)
HHJ44_RS10160	COG3604	Transcriptional regulator
HHJ44_RS10180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HHJ44_RS10185	COG1349	DNA-binding transcription factor activity
HHJ44_RS10190	COG2084	Dehydrogenase
HHJ44_RS10195	COG3395	kinase activity
HHJ44_RS10200	COG0235	Class ii aldolase
HHJ44_RS10205	COG3622	Belongs to the hyi family
HHJ44_RS10210	COG2610	gluconate transmembrane transporter activity
HHJ44_RS10225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHJ44_RS10230	COG1388	LysM domain
HHJ44_RS10230	COG4942	peptidase
HHJ44_RS10285	COG2234	aminopeptidase activity
HHJ44_RS10310	COG0720	synthase
HHJ44_RS10315	COG0644	oxidoreductase
HHJ44_RS10320	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HHJ44_RS10325	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HHJ44_RS10330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HHJ44_RS10335	COG2086	electron transfer activity
HHJ44_RS10340	COG0477	Major facilitator Superfamily
HHJ44_RS10345	COG0277	FAD linked oxidase domain protein
HHJ44_RS10350	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS10355	COG2223	nitrite transmembrane transporter activity
HHJ44_RS10360	COG1070	Carbohydrate kinase
HHJ44_RS10365	COG0602	queuosine metabolic process
HHJ44_RS10375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HHJ44_RS10385	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HHJ44_RS10400	COG3956	TIGRFAM MazG family protein
HHJ44_RS10405	COG2337	Toxic component of a toxin-antitoxin (TA) module
HHJ44_RS10410	COG2336	PFAM SpoVT AbrB
HHJ44_RS10415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHJ44_RS10425	COG3850	Histidine kinase
HHJ44_RS10425	COG4999	Histidine kinase
HHJ44_RS10425	COG2205	protein histidine kinase activity
HHJ44_RS10425	COG3437	response regulator, receiver
HHJ44_RS10430	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ44_RS10435	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ44_RS10440	COG2271	Major facilitator Superfamily
HHJ44_RS10445	COG0716	FMN binding
HHJ44_RS10450	COG0564	pseudouridine synthase activity
HHJ44_RS10455	COG3098	single-species biofilm formation
HHJ44_RS10470	COG1611	Belongs to the LOG family
HHJ44_RS10475	COG0814	amino acid
HHJ44_RS10480	COG1760	l-serine dehydratase
HHJ44_RS10490	COG1454	alcohol dehydrogenase
HHJ44_RS10495	COG0235	Class ii aldolase
HHJ44_RS10500	COG0738	Major facilitator superfamily
HHJ44_RS10510	COG1070	Carbohydrate kinase
HHJ44_RS10520	COG1349	DNA-binding transcription factor activity
HHJ44_RS10530	COG2363	Small membrane protein
HHJ44_RS10535	COG0583	DNA-binding transcription factor activity
HHJ44_RS10545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHJ44_RS10550	COG2166	iron-sulfur cluster assembly
HHJ44_RS10555	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HHJ44_RS10560	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HHJ44_RS10600	COG2885	chlorophyll binding
HHJ44_RS10705	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HHJ44_RS10710	COG1263	PTS System
HHJ44_RS10710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS10715	COG3711	transcriptional antiterminator
HHJ44_RS10720	COG0860	N-Acetylmuramoyl-L-alanine amidase
HHJ44_RS10725	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HHJ44_RS10725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HHJ44_RS10730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HHJ44_RS10735	COG1074	ATP-dependent DNA helicase activity
HHJ44_RS10740	COG1025	Belongs to the peptidase M16 family
HHJ44_RS10745	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HHJ44_RS10750	COG4967	type IV pilus modification protein PilV
HHJ44_RS10760	COG4795	General secretion pathway protein
HHJ44_RS10765	COG2165	general secretion pathway protein
HHJ44_RS10780	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HHJ44_RS10795	COG0861	Integral membrane protein TerC family
HHJ44_RS10805	COG0667	Aldo Keto reductase
HHJ44_RS10820	COG1609	Transcriptional regulator
HHJ44_RS10830	COG0583	DNA-binding transcription factor activity
HHJ44_RS10835	COG1794	racemase activity, acting on amino acids and derivatives
HHJ44_RS10840	COG2814	Major facilitator Superfamily
HHJ44_RS10845	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS10855	COG0183	Belongs to the thiolase family
HHJ44_RS10860	COG0814	amino acid
HHJ44_RS10870	COG4942	peptidase
HHJ44_RS10875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HHJ44_RS10880	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HHJ44_RS10885	COG2080	2 iron, 2 sulfur cluster binding
HHJ44_RS10895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHJ44_RS10900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHJ44_RS10905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HHJ44_RS10915	COG0549	Belongs to the carbamate kinase family
HHJ44_RS10920	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HHJ44_RS10920	COG3608	succinylglutamate desuccinylase aspartoacylase
HHJ44_RS10925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHJ44_RS10930	COG2068	MobA-Related Protein
HHJ44_RS10935	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ44_RS10935	COG0493	'glutamate synthase
HHJ44_RS10940	COG0402	S-adenosylhomocysteine deaminase activity
HHJ44_RS10945	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HHJ44_RS10950	COG2080	2 iron, 2 sulfur cluster binding
HHJ44_RS10950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HHJ44_RS10955	COG2233	PERMEase
HHJ44_RS10960	COG0402	S-adenosylhomocysteine deaminase activity
HHJ44_RS10965	COG2252	PERMEase
HHJ44_RS10970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ44_RS10980	COG2233	PERMEase
HHJ44_RS11000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HHJ44_RS11010	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HHJ44_RS11015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HHJ44_RS11025	COG0716	FMN binding
HHJ44_RS11035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HHJ44_RS11045	COG1272	protein, Hemolysin III
HHJ44_RS11055	COG2723	6-phospho-beta-galactosidase activity
HHJ44_RS11080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HHJ44_RS11085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HHJ44_RS11090	COG0006	proline dipeptidase activity
HHJ44_RS11110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHJ44_RS11120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HHJ44_RS11140	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HHJ44_RS11140	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HHJ44_RS11145	COG0583	DNA-binding transcription factor activity
HHJ44_RS11150	COG2968	Membrane
HHJ44_RS11155	COG1279	arginine transmembrane transporter activity
HHJ44_RS11160	COG0668	transmembrane transport
HHJ44_RS11165	COG0191	fructose-bisphosphate aldolase activity
HHJ44_RS11200	COG1122	ATPase activity
HHJ44_RS11205	COG1072	(Pantothenic acid kinase))
HHJ44_RS11220	COG1063	alcohol dehydrogenase
HHJ44_RS11225	COG2213	PTS system mannitol-specific
HHJ44_RS11230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS11235	COG0330	HflC and HflK could
HHJ44_RS11240	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHJ44_RS11245	COG0501	Belongs to the peptidase M48B family
HHJ44_RS11260	COG1166	arginine decarboxylase activity
HHJ44_RS11280	COG2814	Major facilitator Superfamily
HHJ44_RS11290	COG2356	endonuclease I
HHJ44_RS11295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HHJ44_RS11300	COG0189	ligase activity
HHJ44_RS11315	COG2805	Type II/IV secretion system protein
HHJ44_RS11320	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHJ44_RS11325	COG0762	integral membrane protein
HHJ44_RS11335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHJ44_RS11340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HHJ44_RS11350	COG0252	asparaginase activity
HHJ44_RS11360	COG3171	Protein conserved in bacteria
HHJ44_RS11370	COG1194	a g-specific adenine glycosylase
HHJ44_RS11385	COG2211	Major facilitator Superfamily
HHJ44_RS11390	COG1982	Orn Lys Arg decarboxylase major
HHJ44_RS11395	COG1811	Na channel or pump
HHJ44_RS11405	COG0582	viral genome integration into host DNA
HHJ44_RS11410	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HHJ44_RS11410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHJ44_RS11415	COG2194	sulfuric ester hydrolase activity
HHJ44_RS11555	COG3969	phosphoadenosine phosphosulfate
HHJ44_RS11580	COG4771	TonB-dependent receptor
HHJ44_RS11605	COG3596	GTP binding
HHJ44_RS11610	COG2378	regulation of single-species biofilm formation
HHJ44_RS11635	COG2003	Belongs to the UPF0758 family
HHJ44_RS11670	COG2200	EAL domain
HHJ44_RS11670	COG2771	luxR family
HHJ44_RS11740	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HHJ44_RS11755	COG4795	General secretion pathway protein
HHJ44_RS11770	COG2165	general secretion pathway protein
HHJ44_RS11775	COG1459	type II secretion system
HHJ44_RS11780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHJ44_RS11790	COG3031	protein transport across the cell outer membrane
HHJ44_RS11805	COG3064	Membrane
HHJ44_RS11810	COG1620	l-lactate permease
HHJ44_RS11815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HHJ44_RS11820	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HHJ44_RS11825	COG0247	lactate metabolic process
HHJ44_RS11830	COG0277	FAD linked oxidase domain protein
HHJ44_RS11835	COG0277	FAD linked oxidase domain protein
HHJ44_RS11840	COG2186	Transcriptional regulator
HHJ44_RS11845	COG0456	acetyltransferase
HHJ44_RS11850	COG0318	PFAM AMP-dependent synthetase and ligase
HHJ44_RS11860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHJ44_RS11865	COG0156	8-amino-7-oxononanoate synthase activity
HHJ44_RS11875	COG0795	lipopolysaccharide-transporting ATPase activity
HHJ44_RS11880	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HHJ44_RS11890	COG2244	polysaccharide biosynthetic process
HHJ44_RS11895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHJ44_RS11900	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHJ44_RS11905	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHJ44_RS11910	COG0306	phosphate transporter
HHJ44_RS11915	COG0754	glutathionylspermidine amidase activity
HHJ44_RS11920	COG0625	glutathione transferase activity
HHJ44_RS11925	COG0298	carbon dioxide binding
HHJ44_RS11930	COG0375	protein maturation
HHJ44_RS11935	COG1773	rubredoxin
HHJ44_RS11940	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHJ44_RS11945	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HHJ44_RS11950	COG5557	Pfam Polysulphide reductase, NrfD
HHJ44_RS11955	COG0437	4 iron, 4 sulfur cluster binding
HHJ44_RS11960	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HHJ44_RS11975	COG0667	Aldo Keto reductase
HHJ44_RS11985	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS11990	COG0848	biopolymer transport protein
HHJ44_RS11995	COG0811	peptide transport
HHJ44_RS12000	COG0626	cystathionine gamma-synthase activity
HHJ44_RS12005	COG0586	Pfam SNARE associated Golgi protein
HHJ44_RS12010	COG2207	Transcriptional regulator
HHJ44_RS12015	COG1979	alcohol dehydrogenase
HHJ44_RS12020	COG0656	L-ascorbic acid biosynthetic process
HHJ44_RS12030	COG4238	major outer membrane lipoprotein
HHJ44_RS12035	COG1032	radical SAM domain protein
HHJ44_RS12040	COG2186	Transcriptional regulator
HHJ44_RS12045	COG0246	Mannitol dehydrogenase
HHJ44_RS12050	COG1063	alcohol dehydrogenase
HHJ44_RS12055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HHJ44_RS12075	COG2132	Multicopper oxidase
HHJ44_RS12080	COG0204	Acyl-transferase
HHJ44_RS12085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHJ44_RS12090	COG4166	transmembrane transport
HHJ44_RS12095	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HHJ44_RS12100	COG3111	PFAM Bacterial OB fold (BOF) protein
HHJ44_RS12105	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS12110	COG0642	Histidine kinase
HHJ44_RS12125	COG2249	NAD(P)H dehydrogenase (quinone) activity
HHJ44_RS12130	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HHJ44_RS12135	COG1737	Transcriptional regulator
HHJ44_RS12145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ44_RS12150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ44_RS12155	COG1120	ATPase activity
HHJ44_RS12160	COG4774	siderophore transport
HHJ44_RS12165	COG0187	DNA topoisomerase II activity
HHJ44_RS12170	COG3150	esterase
HHJ44_RS12175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HHJ44_RS12180	COG3151	Protein conserved in bacteria
HHJ44_RS12185	COG0494	nUDIX hydrolase
HHJ44_RS12190	COG1538	Outer membrane efflux protein
HHJ44_RS12200	COG0754	glutathionylspermidine amidase activity
HHJ44_RS12210	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HHJ44_RS12220	COG3384	dioxygenase
HHJ44_RS12235	COG3539	Fimbrial protein
HHJ44_RS12240	COG3188	usher protein
HHJ44_RS12245	COG3121	Chaperone
HHJ44_RS12250	COG3539	Fimbrial protein
HHJ44_RS12270	COG1585	Membrane protein implicated in regulation of membrane protease activity
HHJ44_RS12275	COG2268	Band 7 protein
HHJ44_RS12295	COG3025	triphosphatase activity
HHJ44_RS12300	COG4991	sh3 domain protein
HHJ44_RS12315	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHJ44_RS12335	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ44_RS12350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HHJ44_RS12355	COG0358	DNA primase activity
HHJ44_RS12360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHJ44_RS12375	COG2375	cellular response to nickel ion
HHJ44_RS12380	COG1695	Transcriptional regulator
HHJ44_RS12385	COG0840	transmembrane signaling receptor activity
HHJ44_RS12395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHJ44_RS12400	COG1609	Transcriptional regulator
HHJ44_RS12405	COG3250	beta-galactosidase activity
HHJ44_RS12410	COG2731	YhcH YjgK YiaL family protein
HHJ44_RS12415	COG0531	amino acid
HHJ44_RS12425	COG3408	Glycogen debranching enzyme
HHJ44_RS12425	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HHJ44_RS12430	COG1902	pentaerythritol trinitrate reductase activity
HHJ44_RS12430	COG0446	pyridine nucleotide-disulphide oxidoreductase
HHJ44_RS12440	COG1451	nucleotide metabolic process
HHJ44_RS12445	COG2949	membrane
HHJ44_RS12450	COG0673	inositol 2-dehydrogenase activity
HHJ44_RS12455	COG0861	Integral membrane protein TerC family
HHJ44_RS12470	COG2721	sulfolactate sulfo-lyase activity
HHJ44_RS12480	COG2271	Major facilitator Superfamily
HHJ44_RS12485	COG2186	Transcriptional regulator
HHJ44_RS12490	COG0586	Pfam SNARE associated Golgi protein
HHJ44_RS12500	COG1422	Protein of unknown function (DUF1090)
HHJ44_RS12505	COG4575	ribosome binding
HHJ44_RS12510	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HHJ44_RS12520	COG2259	Doxx family
HHJ44_RS12525	COG0435	Glutathione S-transferase
HHJ44_RS12530	COG3152	Membrane
HHJ44_RS12535	COG0583	DNA-binding transcription factor activity
HHJ44_RS12540	COG1741	Belongs to the pirin family
HHJ44_RS12555	COG0814	amino acid
HHJ44_RS12560	COG1760	l-serine dehydratase
HHJ44_RS12565	COG0251	oxidation-reduction process
HHJ44_RS12570	COG1882	Formate acetyltransferase
HHJ44_RS12575	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHJ44_RS12585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHJ44_RS12590	COG0583	DNA-binding transcription factor activity
HHJ44_RS12605	COG1929	Belongs to the glycerate kinase type-1 family
HHJ44_RS12610	COG2084	Dehydrogenase
HHJ44_RS12620	COG2271	Major facilitator Superfamily
HHJ44_RS12625	COG2721	sulfolactate sulfo-lyase activity
HHJ44_RS12630	COG1349	DNA-binding transcription factor activity
HHJ44_RS12640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS12650	COG3716	PTS system mannose fructose sorbose family IID component
HHJ44_RS12655	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS12660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHJ44_RS12665	COG2222	sugar isomerase
HHJ44_RS12675	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS12680	COG3715	PTS system
HHJ44_RS12685	COG3716	PTS system mannose fructose sorbose family IID component
HHJ44_RS12690	COG0363	glucosamine-6-phosphate deaminase activity
HHJ44_RS12695	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHJ44_RS12700	COG3107	peptidoglycan biosynthetic process
HHJ44_RS12715	COG2823	Periplasmic or secreted lipoprotein
HHJ44_RS12720	COG0701	Predicted permease
HHJ44_RS12725	COG0702	epimerase
HHJ44_RS12730	COG0693	protein deglycase activity
HHJ44_RS12745	COG3153	acetyltransferase
HHJ44_RS12750	COG3154	lipid carrier protein
HHJ44_RS12755	COG0826	peptidase U32
HHJ44_RS12760	COG0826	peptidase U32
HHJ44_RS12765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHJ44_RS12770	COG0814	amino acid
HHJ44_RS12775	COG0513	Belongs to the DEAD box helicase family
HHJ44_RS12815	COG0195	Participates in both transcription termination and antitermination
HHJ44_RS12835	COG2194	sulfuric ester hydrolase activity
HHJ44_RS12845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HHJ44_RS12855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HHJ44_RS12860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHJ44_RS12870	COG1534	Rna-binding protein
HHJ44_RS12875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HHJ44_RS12880	COG2027	D-alanyl-D-alanine carboxypeptidase
HHJ44_RS12890	COG0697	spore germination
HHJ44_RS12905	COG0142	geranyltranstransferase activity
HHJ44_RS12910	COG3423	Transcriptional regulator
HHJ44_RS12920	COG5007	Belongs to the BolA IbaG family
HHJ44_RS12925	COG3113	response to antibiotic
HHJ44_RS12930	COG2854	intermembrane phospholipid transfer
HHJ44_RS12935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HHJ44_RS12940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HHJ44_RS12945	COG1127	ABC transporter
HHJ44_RS12950	COG0530	calcium, potassium:sodium antiporter activity
HHJ44_RS12955	COG0517	IMP dehydrogenase activity
HHJ44_RS12955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HHJ44_RS12960	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HHJ44_RS12965	COG3117	lipopolysaccharide transmembrane transporter activity
HHJ44_RS12970	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HHJ44_RS12975	COG1137	ATPase activity
HHJ44_RS12980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HHJ44_RS12985	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHJ44_RS13000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS13005	COG0515	serine threonine protein kinase
HHJ44_RS13015	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HHJ44_RS13020	COG5002	protein histidine kinase activity
HHJ44_RS13020	COG2198	Histidine kinase
HHJ44_RS13020	COG0784	Response regulator, receiver
HHJ44_RS13025	COG1242	4 iron, 4 sulfur cluster binding
HHJ44_RS13030	COG0067	glutamate synthase
HHJ44_RS13030	COG0069	glutamate synthase activity
HHJ44_RS13030	COG0070	glutamate synthase
HHJ44_RS13035	COG0493	'glutamate synthase
HHJ44_RS13040	COG2731	YhcH YjgK YiaL family protein
HHJ44_RS13070	COG2969	positive regulation of protein catabolic process
HHJ44_RS13075	COG0625	glutathione transferase activity
HHJ44_RS13090	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HHJ44_RS13095	COG3105	Protein conserved in bacteria
HHJ44_RS13100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHJ44_RS13105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHJ44_RS13125	COG2732	(Barnase) inhibitor
HHJ44_RS13145	COG0583	DNA-binding transcription factor activity
HHJ44_RS13150	COG0312	modulator of DNA gyrase
HHJ44_RS13155	COG3164	Protein of unknown function
HHJ44_RS13160	COG1530	ribonuclease E activity
HHJ44_RS13170	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HHJ44_RS13175	COG1792	Involved in formation and maintenance of cell shape
HHJ44_RS13180	COG1077	Cell shape determining protein MreB Mrl
HHJ44_RS13185	COG2199	diguanylate cyclase activity
HHJ44_RS13185	COG2200	EAL domain
HHJ44_RS13190	COG0604	alcohol dehydrogenase
HHJ44_RS13200	COG0511	ligase activity, forming carbon-carbon bonds
HHJ44_RS13205	COG0439	Biotin carboxylase
HHJ44_RS13215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS13220	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ44_RS13225	COG1129	ABC transporter
HHJ44_RS13230	COG1879	ABC-type sugar transport system periplasmic component
HHJ44_RS13240	COG1349	DNA-binding transcription factor activity
HHJ44_RS13245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS13250	COG3924	membrane
HHJ44_RS13255	COG4145	pantothenate transmembrane transporter activity
HHJ44_RS13265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHJ44_RS13275	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HHJ44_RS13285	COG1309	transcriptional regulator
HHJ44_RS13290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ44_RS13295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ44_RS13305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ44_RS13310	COG4597	amino acid ABC transporter
HHJ44_RS13315	COG0765	amino acid transport
HHJ44_RS13320	COG1126	abc transporter atp-binding protein
HHJ44_RS13355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HHJ44_RS13375	COG0551	DNA topoisomerase type I activity
HHJ44_RS13385	COG0758	DNA mediated transformation
HHJ44_RS13405	COG0569	domain protein
HHJ44_RS13415	COG3036	rescue of stalled ribosome
HHJ44_RS13420	COG0789	Transcriptional regulator
HHJ44_RS13460	COG0201	protein transport
HHJ44_RS13550	COG0089	rRNA binding
HHJ44_RS13575	COG3267	Type II secretory pathway component ExeA
HHJ44_RS13575	COG3409	Peptidoglycan-binding domain 1 protein
HHJ44_RS13580	COG3031	protein transport across the cell outer membrane
HHJ44_RS13585	COG1450	Type ii and iii secretion system protein
HHJ44_RS13590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHJ44_RS13595	COG1459	type II secretion system
HHJ44_RS13600	COG2165	general secretion pathway protein
HHJ44_RS13605	COG2165	general secretion pathway protein
HHJ44_RS13610	COG2165	general secretion pathway protein
HHJ44_RS13615	COG4795	General secretion pathway protein
HHJ44_RS13620	COG3156	type II secretion system protein K
HHJ44_RS13625	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HHJ44_RS13630	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HHJ44_RS13635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HHJ44_RS13640	COG2193	ferroxidase activity
HHJ44_RS13645	COG2906	2 iron, 2 sulfur cluster binding
HHJ44_RS13650	COG3979	chitinase
HHJ44_RS13690	COG2964	Protein conserved in bacteria
HHJ44_RS13695	COG0545	Peptidyl-prolyl cis-trans isomerase
HHJ44_RS13705	COG1047	Peptidyl-prolyl cis-trans
HHJ44_RS13710	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HHJ44_RS13725	COG0488	(ABC) transporter
HHJ44_RS13730	COG0429	hydrolase of the alpha beta-hydrolase fold
HHJ44_RS13740	COG3954	Phosphoribulokinase
HHJ44_RS13745	COG1765	OsmC-like protein
HHJ44_RS13750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HHJ44_RS13755	COG1289	transmembrane transporter activity
HHJ44_RS13760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HHJ44_RS13765	COG0512	Glutamine amidotransferase of anthranilate synthase
HHJ44_RS13770	COG2184	nucleotidyltransferase activity
HHJ44_RS13780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHJ44_RS13790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HHJ44_RS13795	COG2146	nitrite reductase [NAD(P)H] activity
HHJ44_RS13800	COG2116	formate transmembrane transporter activity
HHJ44_RS13815	COG0626	cystathionine gamma-synthase activity
HHJ44_RS13830	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HHJ44_RS13835	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHJ44_RS13840	COG3457	Alanine racemase
HHJ44_RS13850	COG2188	Transcriptional regulator
HHJ44_RS13855	COG0180	Tryptophanyl-tRNA synthetase
HHJ44_RS13860	COG0546	phosphoglycolate phosphatase activity
HHJ44_RS13865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HHJ44_RS13870	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HHJ44_RS13875	COG3266	domain, Protein
HHJ44_RS13890	COG4796	Type ii and iii secretion system protein
HHJ44_RS13905	COG3166	PFAM Fimbrial assembly family protein
HHJ44_RS13910	COG4972	Pilus assembly protein
HHJ44_RS13915	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HHJ44_RS13920	COG0494	nUDIX hydrolase
HHJ44_RS13930	COG1011	Hydrolase
HHJ44_RS13935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HHJ44_RS13945	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HHJ44_RS13955	COG2205	protein histidine kinase activity
HHJ44_RS13960	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS13965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HHJ44_RS13970	COG2183	response to ionizing radiation
HHJ44_RS13975	COG1918	ferrous iron import across plasma membrane
HHJ44_RS13980	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HHJ44_RS13990	COG5464	transposase or invertase
HHJ44_RS14000	COG1040	competence protein
HHJ44_RS14010	COG2610	gluconate transmembrane transporter activity
HHJ44_RS14015	COG1640	4-alpha-glucanotransferase
HHJ44_RS14020	COG0058	SHG alpha-glucan phosphorylase activity
HHJ44_RS14035	COG1690	Belongs to the RtcB family
HHJ44_RS14040	COG4650	regulator
HHJ44_RS14045	COG1349	DNA-binding transcription factor activity
HHJ44_RS14060	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HHJ44_RS14100	COG3188	usher protein
HHJ44_RS14105	COG3121	Chaperone
HHJ44_RS14115	COG0058	SHG alpha-glucan phosphorylase activity
HHJ44_RS14140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHJ44_RS14145	COG2095	MarC family integral membrane protein
HHJ44_RS14150	COG2610	gluconate transmembrane transporter activity
HHJ44_RS14155	COG3265	gluconokinase activity
HHJ44_RS14160	COG1609	Transcriptional regulator
HHJ44_RS14165	COG1741	Belongs to the pirin family
HHJ44_RS14170	COG0673	inositol 2-dehydrogenase activity
HHJ44_RS14175	COG1247	-acetyltransferase
HHJ44_RS14180	COG3157	Type VI secretion system effector, Hcp
HHJ44_RS14185	COG3157	Type VI secretion system effector, Hcp
HHJ44_RS14205	COG0405	Gamma-glutamyltransferase
HHJ44_RS14215	COG0584	glycerophosphoryl diester phosphodiesterase
HHJ44_RS14240	COG0410	ABC transporter
HHJ44_RS14245	COG0411	ABC transporter
HHJ44_RS14250	COG4177	L-phenylalanine transmembrane transporter activity
HHJ44_RS14255	COG0559	Belongs to the binding-protein-dependent transport system permease family
HHJ44_RS14260	COG0683	leucine binding
HHJ44_RS14265	COG0456	acetyltransferase
HHJ44_RS14270	COG0683	leucine binding
HHJ44_RS14295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHJ44_RS14300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHJ44_RS14305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHJ44_RS14310	COG2177	Part of the ABC transporter FtsEX involved in
HHJ44_RS14315	COG2884	Cell division ATP-binding protein ftsE
HHJ44_RS14320	COG0552	protein localization to endoplasmic reticulum
HHJ44_RS14325	COG0742	ribosomal rna small subunit methyltransferase
HHJ44_RS14330	COG3776	membrane
HHJ44_RS14340	COG3714	YhhN family
HHJ44_RS14355	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HHJ44_RS14365	COG0477	Major facilitator Superfamily
HHJ44_RS14370	COG0628	permease
HHJ44_RS14375	COG2091	lysine biosynthetic process via aminoadipic acid
HHJ44_RS14380	COG0747	negative chemotaxis
HHJ44_RS14385	COG0601	transmembrane transport
HHJ44_RS14390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHJ44_RS14410	COG2188	Transcriptional regulator
HHJ44_RS14420	COG3414	Phosphotransferase system galactitol-specific IIB component
HHJ44_RS14425	COG3775	system Galactitol-specific IIC component
HHJ44_RS14440	COG0191	fructose-bisphosphate aldolase activity
HHJ44_RS14445	COG0842	Transport permease protein
HHJ44_RS14450	COG1129	ABC transporter
HHJ44_RS14450	COG0842	Transport permease protein
HHJ44_RS14455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ44_RS14465	COG2081	HI0933 family
HHJ44_RS14470	COG0306	phosphate transporter
HHJ44_RS14480	COG0589	response to stress
HHJ44_RS14485	COG3104	oligopeptide transport
HHJ44_RS14495	COG0339	signal peptide processing
HHJ44_RS14500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HHJ44_RS14505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHJ44_RS14515	COG1393	Belongs to the ArsC family
HHJ44_RS14525	COG3065	identical protein binding
HHJ44_RS14530	COG2197	response regulator
HHJ44_RS14535	COG3720	iron ion transport
HHJ44_RS14540	COG4771	TonB-dependent receptor
HHJ44_RS14555	COG3721	Heme iron utilization protein
HHJ44_RS14565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ44_RS14575	COG1285	pathogenesis
HHJ44_RS14590	COG3247	response to pH
HHJ44_RS14595	COG2771	luxR family
HHJ44_RS14605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ44_RS14610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ44_RS14615	COG2207	Transcriptional regulator
HHJ44_RS14620	COG2207	Transcriptional regulator
HHJ44_RS14625	COG0076	glutamate decarboxylase activity
HHJ44_RS14630	COG1858	cytochrome C peroxidase
HHJ44_RS14640	COG2197	response regulator
HHJ44_RS14645	COG0583	DNA-binding transcription factor activity
HHJ44_RS14650	COG1295	ribonuclease BN
HHJ44_RS14655	COG0477	Major facilitator Superfamily
HHJ44_RS14660	COG2982	Protein involved in outer membrane biogenesis
HHJ44_RS14665	COG2200	EAL domain
HHJ44_RS14670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS14675	COG0612	Peptidase, M16
HHJ44_RS14685	COG2199	diguanylate cyclase activity
HHJ44_RS14685	COG2200	EAL domain
HHJ44_RS14690	COG3118	belongs to the thioredoxin family
HHJ44_RS14690	COG0457	Tetratricopeptide repeat
HHJ44_RS14695	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HHJ44_RS14700	COG1215	transferase activity, transferring glycosyl groups
HHJ44_RS14705	COG1215	transferase activity, transferring glycosyl groups
HHJ44_RS14730	COG0814	amino acid
HHJ44_RS14735	COG4608	Belongs to the ABC transporter superfamily
HHJ44_RS14740	COG0444	Belongs to the ABC transporter superfamily
HHJ44_RS14745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHJ44_RS14750	COG0601	transmembrane transport
HHJ44_RS14755	COG0747	negative chemotaxis
HHJ44_RS14765	COG2194	sulfuric ester hydrolase activity
HHJ44_RS14770	COG2223	nitrite transmembrane transporter activity
HHJ44_RS14775	COG5571	outer membrane autotransporter
HHJ44_RS14780	COG2818	Glycosylase
HHJ44_RS14785	COG0456	acetyltransferase
HHJ44_RS14790	COG0243	molybdopterin cofactor binding
HHJ44_RS14795	COG2885	chlorophyll binding
HHJ44_RS14810	COG2944	sequence-specific DNA binding
HHJ44_RS14815	COG1278	Cold shock
HHJ44_RS14840	COG3274	enterobacterial common antigen metabolic process
HHJ44_RS14845	COG4682	membrane
HHJ44_RS14850	COG4682	membrane
HHJ44_RS14855	COG1070	Carbohydrate kinase
HHJ44_RS14865	COG4213	ABC transporter substrate-binding protein
HHJ44_RS14875	COG4214	carbohydrate transport
HHJ44_RS14880	COG2207	Transcriptional regulator
HHJ44_RS14880	COG1609	Transcriptional regulator
HHJ44_RS14885	COG2992	FlgJ-related protein
HHJ44_RS14890	COG0366	Alpha amylase catalytic
HHJ44_RS14895	COG3977	Valine--pyruvate aminotransferase
HHJ44_RS14900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HHJ44_RS14905	COG1414	Transcriptional regulator
HHJ44_RS14915	COG2731	YhcH YjgK YiaL family protein
HHJ44_RS14925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HHJ44_RS14930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HHJ44_RS14935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HHJ44_RS14940	COG1070	Carbohydrate kinase
HHJ44_RS14945	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HHJ44_RS14950	COG3623	hexulose-6-phosphate isomerase
HHJ44_RS14955	COG0235	Class ii aldolase
HHJ44_RS14960	COG1012	belongs to the aldehyde dehydrogenase family
HHJ44_RS14970	COG1454	alcohol dehydrogenase
HHJ44_RS14975	COG3276	selenocysteine insertion sequence binding
HHJ44_RS14985	COG0625	glutathione transferase activity
HHJ44_RS14990	COG1566	PFAM secretion protein HlyD family protein
HHJ44_RS15000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS15000	COG2213	PTS system mannitol-specific
HHJ44_RS15010	COG3722	fumarate hydratase activity
HHJ44_RS15030	COG5295	Hep Hag repeat protein
HHJ44_RS15035	COG1620	l-lactate permease
HHJ44_RS15040	COG2186	Transcriptional regulator
HHJ44_RS15050	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HHJ44_RS15055	COG1045	serine acetyltransferase
HHJ44_RS15070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HHJ44_RS15075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHJ44_RS15085	COG4942	peptidase
HHJ44_RS15090	COG2861	carbohydrate metabolic process
HHJ44_RS15095	COG1216	Glycosyl transferase, family 2
HHJ44_RS15105	COG0156	8-amino-7-oxononanoate synthase activity
HHJ44_RS15115	COG0859	PFAM glycosyl transferase family 9
HHJ44_RS15120	COG0859	PFAM glycosyl transferase family 9
HHJ44_RS15125	COG3307	-O-antigen
HHJ44_RS15130	COG1216	Glycosyl transferase, family 2
HHJ44_RS15135	COG1442	glycosyl transferase family 8
HHJ44_RS15140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HHJ44_RS15155	COG0515	serine threonine protein kinase
HHJ44_RS15160	COG0438	transferase activity, transferring glycosyl groups
HHJ44_RS15165	COG0859	PFAM glycosyl transferase family 9
HHJ44_RS15170	COG1519	Transferase
HHJ44_RS15200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHJ44_RS15225	COG1561	YicC-like family, N-terminal region
HHJ44_RS15340	COG3645	SOS response
HHJ44_RS15345	COG2860	membrane
HHJ44_RS15355	COG0194	GDP metabolic process
HHJ44_RS15365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHJ44_RS15370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHJ44_RS15375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHJ44_RS15380	COG0786	glutamate:sodium symporter activity
HHJ44_RS15385	COG2233	PERMEase
HHJ44_RS15390	COG2982	Protein involved in outer membrane biogenesis
HHJ44_RS15400	COG1940	carbohydrate kinase activity
HHJ44_RS15415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS15415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS15420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS15425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS15425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS15425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS15430	COG3711	transcriptional antiterminator
HHJ44_RS15435	COG1501	Belongs to the glycosyl hydrolase 31 family
HHJ44_RS15440	COG2211	Major facilitator Superfamily
HHJ44_RS15460	COG0697	spore germination
HHJ44_RS15465	COG1464	Belongs to the NlpA lipoprotein family
HHJ44_RS15485	COG2252	PERMEase
HHJ44_RS15495	COG2271	Major facilitator Superfamily
HHJ44_RS15500	COG2271	Major facilitator Superfamily
HHJ44_RS15505	COG3851	Histidine kinase
HHJ44_RS15510	COG2197	response regulator
HHJ44_RS15515	COG0440	acetolactate synthase activity
HHJ44_RS15520	COG0028	Belongs to the TPP enzyme family
HHJ44_RS15530	COG2814	Major facilitator Superfamily
HHJ44_RS15535	COG0641	radical SAM
HHJ44_RS15545	COG2149	membrane
HHJ44_RS15555	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHJ44_RS15560	COG2207	Transcriptional regulator
HHJ44_RS15580	COG5645	(Lipo)protein
HHJ44_RS15585	COG0823	Involved in the tonB-independent uptake of proteins
HHJ44_RS15595	COG2271	Major facilitator Superfamily
HHJ44_RS15605	COG0800	Aldolase
HHJ44_RS15610	COG3734	2-keto-3-deoxy-galactonokinase
HHJ44_RS15615	COG2186	Transcriptional regulator
HHJ44_RS15625	COG0561	phosphatase activity
HHJ44_RS15630	COG3753	Protein conserved in bacteria
HHJ44_RS15635	COG0187	DNA topoisomerase II activity
HHJ44_RS15645	COG0592	DNA-directed DNA polymerase activity
HHJ44_RS15695	COG0814	amino acid
HHJ44_RS15705	COG0583	DNA-binding transcription factor activity
HHJ44_RS15710	COG2091	lysine biosynthetic process via aminoadipic acid
HHJ44_RS15715	COG0431	NADPH-dependent FMN reductase
HHJ44_RS15720	COG2252	PERMEase
HHJ44_RS15735	COG0363	glucosamine-6-phosphate deaminase activity
HHJ44_RS15740	COG2382	esterase
HHJ44_RS15750	COG2723	6-phospho-beta-galactosidase activity
HHJ44_RS15755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS15755	COG2190	(PTS) system
HHJ44_RS15755	COG1263	PTS System
HHJ44_RS15760	COG3711	transcriptional antiterminator
HHJ44_RS15765	COG0704	Plays a role in the regulation of phosphate uptake
HHJ44_RS15770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HHJ44_RS15775	COG0581	inorganic phosphate transmembrane transporter activity
HHJ44_RS15780	COG0573	inorganic phosphate transmembrane transporter activity
HHJ44_RS15785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HHJ44_RS15840	COG3312	ion transport
HHJ44_RS15855	COG0716	FMN binding
HHJ44_RS15860	COG1522	sequence-specific DNA binding
HHJ44_RS15895	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ44_RS15900	COG1879	ABC-type sugar transport system periplasmic component
HHJ44_RS15905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS15910	COG1609	Transcriptional regulator
HHJ44_RS15915	COG0477	Major facilitator Superfamily
HHJ44_RS15920	COG2186	Transcriptional regulator
HHJ44_RS15960	COG3085	chromosome segregation
HHJ44_RS15965	COG0606	chelatase, subunit chli
HHJ44_RS15985	COG3978	acetolactate synthase activity
HHJ44_RS15990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HHJ44_RS16000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHJ44_RS16005	COG0583	DNA-binding transcription factor activity
HHJ44_RS16015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HHJ44_RS16020	COG0210	DNA helicase
HHJ44_RS16035	COG3118	belongs to the thioredoxin family
HHJ44_RS16045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HHJ44_RS16050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHJ44_RS16055	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HHJ44_RS16060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HHJ44_RS16065	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HHJ44_RS16070	COG1088	dTDP-glucose 4,6-dehydratase activity
HHJ44_RS16075	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHJ44_RS16080	COG0456	acetyltransferase
HHJ44_RS16085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HHJ44_RS16090	COG2244	polysaccharide biosynthetic process
HHJ44_RS16110	COG1113	amino acid transport
HHJ44_RS16135	COG0641	radical SAM
HHJ44_RS16140	COG3119	arylsulfatase activity
HHJ44_RS16145	COG3071	HemY protein
HHJ44_RS16150	COG2959	enzyme of heme biosynthesis
HHJ44_RS16155	COG1587	Uroporphyrinogen-III synthase
HHJ44_RS16165	COG3072	Adenylate cyclase
HHJ44_RS16185	COG5567	small periplasmic lipoprotein
HHJ44_RS16195	COG3159	Protein conserved in bacteria
HHJ44_RS16205	COG1011	Hydrolase
HHJ44_RS16210	COG0210	DNA helicase
HHJ44_RS16215	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HHJ44_RS16220	COG3698	Phosphodiester glycosidase
HHJ44_RS16225	COG0598	Magnesium transport protein CorA
HHJ44_RS16240	COG2962	Rard protein
HHJ44_RS16245	COG2050	protein possibly involved in aromatic compounds catabolism
HHJ44_RS16250	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HHJ44_RS16255	COG0514	ATP-dependent DNA helicase (RecQ)
HHJ44_RS16260	COG1280	lysine exporter protein (LysE YggA)
HHJ44_RS16265	COG1280	lysine exporter protein (LysE YggA)
HHJ44_RS16270	COG2267	carboxylic ester hydrolase activity
HHJ44_RS16275	COG0561	phosphatase activity
HHJ44_RS16280	COG0697	spore germination
HHJ44_RS16285	COG0583	DNA-binding transcription factor activity
HHJ44_RS16305	COG3157	Type VI secretion system effector, Hcp
HHJ44_RS16315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS16315	COG2190	(PTS) system
HHJ44_RS16315	COG1263	PTS System
HHJ44_RS16320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHJ44_RS16325	COG1737	Transcriptional regulator
HHJ44_RS16330	COG0583	DNA-binding transcription factor activity
HHJ44_RS16335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HHJ44_RS16345	COG0549	Belongs to the carbamate kinase family
HHJ44_RS16350	COG1304	FMN binding
HHJ44_RS16355	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ44_RS16365	COG1335	isochorismatase
HHJ44_RS16370	COG0412	Dienelactone hydrolase
HHJ44_RS16375	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HHJ44_RS16395	COG0800	Aldolase
HHJ44_RS16400	COG3734	2-keto-3-deoxy-galactonokinase
HHJ44_RS16405	COG1414	Transcriptional regulator
HHJ44_RS16410	COG1322	Protein conserved in bacteria
HHJ44_RS16420	COG3165	ubiquinone biosynthetic process from chorismate
HHJ44_RS16430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHJ44_RS16440	COG0805	protein transport
HHJ44_RS16455	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HHJ44_RS16460	COG0543	2 iron, 2 sulfur cluster binding
HHJ44_RS16480	COG1739	Uncharacterized protein family UPF0029
HHJ44_RS16485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HHJ44_RS16490	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HHJ44_RS16520	COG1763	Mo-molybdopterin cofactor biosynthetic process
HHJ44_RS16525	COG0746	molybdenum cofactor guanylyltransferase activity
HHJ44_RS16530	COG3084	Protein conserved in bacteria
HHJ44_RS16535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HHJ44_RS16540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HHJ44_RS16545	COG5339	Protein conserved in bacteria
HHJ44_RS16550	COG0204	Acyl-transferase
HHJ44_RS16555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHJ44_RS16555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHJ44_RS16570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HHJ44_RS16580	COG2204	response regulator
HHJ44_RS16585	COG3852	Histidine kinase
HHJ44_RS16590	COG0174	glutamine synthetase
HHJ44_RS16600	COG1349	DNA-binding transcription factor activity
HHJ44_RS16605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS16610	COG2084	Dehydrogenase
HHJ44_RS16615	COG3684	Belongs to the aldolase LacD family
HHJ44_RS16620	COG1063	alcohol dehydrogenase
HHJ44_RS16630	COG0477	Major facilitator Superfamily
HHJ44_RS16640	COG1011	Hydrolase
HHJ44_RS16655	COG0456	acetyltransferase
HHJ44_RS16665	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HHJ44_RS16690	COG2864	formate dehydrogenase
HHJ44_RS16695	COG0437	4 iron, 4 sulfur cluster binding
HHJ44_RS16755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HHJ44_RS16765	COG2258	MOSC domain
HHJ44_RS16770	COG2205	protein histidine kinase activity
HHJ44_RS16775	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS16780	COG3678	ATP-independent chaperone mediated protein folding
HHJ44_RS16795	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HHJ44_RS16815	COG3152	Membrane
HHJ44_RS16820	COG3691	Protein conserved in bacteria
HHJ44_RS16825	COG0589	response to stress
HHJ44_RS16835	COG1494	fructose-1,6-bisphosphatase
HHJ44_RS16845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HHJ44_RS16860	COG1575	Belongs to the MenA family. Type 1 subfamily
HHJ44_RS16875	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HHJ44_RS16880	COG1609	Transcriptional regulator
HHJ44_RS16885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHJ44_RS16895	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HHJ44_RS16905	COG0626	cystathionine gamma-synthase activity
HHJ44_RS16910	COG0460	homoserine dehydrogenase
HHJ44_RS16910	COG0527	aspartate kinase activity
HHJ44_RS16920	COG0737	Belongs to the 5'-nucleotidase family
HHJ44_RS16925	COG0737	Belongs to the 5'-nucleotidase family
HHJ44_RS16935	COG0737	Belongs to the 5'-nucleotidase family
HHJ44_RS16940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HHJ44_RS16950	COG0697	spore germination
HHJ44_RS16955	COG3738	Protein conserved in bacteria
HHJ44_RS16960	COG0371	Dehydrogenase
HHJ44_RS16965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHJ44_RS16970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS16970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHJ44_RS16970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS16975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS16980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS16985	COG1882	Formate acetyltransferase
HHJ44_RS16990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHJ44_RS16995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HHJ44_RS17000	COG2207	Transcriptional regulator
HHJ44_RS17005	COG2194	sulfuric ester hydrolase activity
HHJ44_RS17020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHJ44_RS17035	COG4948	Mandelate Racemase Muconate Lactonizing
HHJ44_RS17040	COG2271	Major facilitator Superfamily
HHJ44_RS17045	COG0583	DNA-binding transcription factor activity
HHJ44_RS17055	COG1473	amidohydrolase
HHJ44_RS17060	COG0477	Major facilitator Superfamily
HHJ44_RS17110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HHJ44_RS17115	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HHJ44_RS17115	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HHJ44_RS17150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HHJ44_RS17155	COG0250	Participates in transcription elongation, termination and antitermination
HHJ44_RS17190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HHJ44_RS17200	COG2104	thiamine diphosphate biosynthetic process
HHJ44_RS17205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HHJ44_RS17240	COG3068	Protein conserved in bacteria
HHJ44_RS17255	COG3678	ATP-independent chaperone mediated protein folding
HHJ44_RS17260	COG4191	Histidine kinase
HHJ44_RS17265	COG2204	response regulator
HHJ44_RS17270	COG0151	Belongs to the GarS family
HHJ44_RS17305	COG0456	acetyltransferase
HHJ44_RS17315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HHJ44_RS17320	COG2224	Isocitrate lyase
HHJ44_RS17330	COG1414	Transcriptional regulator
HHJ44_RS17335	COG1410	methionine synthase
HHJ44_RS17335	COG0646	methionine synthase
HHJ44_RS17350	COG1283	sodium-dependent phosphate transmembrane transporter activity
HHJ44_RS17395	COG1187	pseudouridine synthase activity
HHJ44_RS17405	COG0527	aspartate kinase activity
HHJ44_RS17430	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ44_RS17445	COG3833	ABC-type maltose transport systems, permease component
HHJ44_RS17450	COG1175	transmembrane transport
HHJ44_RS17455	COG2182	Extracellular solute-binding protein
HHJ44_RS17460	COG3842	ATPase activity
HHJ44_RS17490	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HHJ44_RS17500	COG0534	Mate efflux family protein
HHJ44_RS17505	COG3237	CsbD-like
HHJ44_RS17510	COG0735	belongs to the Fur family
HHJ44_RS17515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHJ44_RS17525	COG0604	alcohol dehydrogenase
HHJ44_RS17530	COG1053	succinate dehydrogenase
HHJ44_RS17535	COG0477	Major facilitator Superfamily
HHJ44_RS17540	COG1024	Enoyl-CoA hydratase
HHJ44_RS17550	COG1609	Transcriptional regulator
HHJ44_RS17555	COG0305	Participates in initiation and elongation during chromosome replication
HHJ44_RS17560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHJ44_RS17565	COG3201	nicotinamide mononucleotide transporter
HHJ44_RS17575	COG1448	Aminotransferase
HHJ44_RS17580	COG0567	Dehydrogenase, E1 component
HHJ44_RS17590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHJ44_RS17595	COG0045	succinate-CoA ligase (ADP-forming) activity
HHJ44_RS17600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ44_RS17605	COG0471	metal ion transport
HHJ44_RS17610	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HHJ44_RS17615	COG2204	response regulator
HHJ44_RS17625	COG3700	Belongs to the class B bacterial acid phosphatase family
HHJ44_RS17630	COG0432	Pfam Uncharacterised protein family UPF0047
HHJ44_RS17635	COG2315	Protein conserved in bacteria
HHJ44_RS17640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HHJ44_RS17645	COG0629	single-stranded DNA binding
HHJ44_RS17655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HHJ44_RS17660	COG2207	Transcriptional regulator
HHJ44_RS17665	COG0789	Transcriptional regulator
HHJ44_RS17670	COG2252	PERMEase
HHJ44_RS17675	COG0025	NhaP-type Na H and K H
HHJ44_RS17680	COG0583	DNA-binding transcription factor activity
HHJ44_RS17685	COG1380	Effector of murein hydrolase LrgA
HHJ44_RS17690	COG1346	cytolysis
HHJ44_RS17700	COG3162	membrane
HHJ44_RS17705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HHJ44_RS17715	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HHJ44_RS17720	COG0437	4 iron, 4 sulfur cluster binding
HHJ44_RS17725	COG3301	Polysulphide reductase, NrfD
HHJ44_RS17730	COG1138	Cytochrome C-type biogenesis protein
HHJ44_RS17735	COG3088	subunit of a heme lyase
HHJ44_RS17740	COG4235	cytochrome complex assembly
HHJ44_RS17745	COG1301	dicarboxylic acid transport
HHJ44_RS17750	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HHJ44_RS17755	COG4608	Belongs to the ABC transporter superfamily
HHJ44_RS17760	COG0444	Belongs to the ABC transporter superfamily
HHJ44_RS17770	COG0601	transmembrane transport
HHJ44_RS17790	COG1289	transmembrane transporter activity
HHJ44_RS17795	COG1566	PFAM secretion protein HlyD family protein
HHJ44_RS17805	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HHJ44_RS17810	COG1940	carbohydrate kinase activity
HHJ44_RS17815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HHJ44_RS17825	COG1129	ABC transporter
HHJ44_RS17830	COG1879	ABC-type sugar transport system periplasmic component
HHJ44_RS17835	COG1737	Transcriptional regulator
HHJ44_RS17840	COG0698	ribose 5-phosphate isomerase
HHJ44_RS17850	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HHJ44_RS17855	COG0456	acetyltransferase
HHJ44_RS17865	COG3454	Phosphonate metabolism
HHJ44_RS17870	COG4778	phosphonate C-P lyase system protein PhnL
HHJ44_RS17875	COG4107	phosphonate C-P lyase system protein PhnK
HHJ44_RS17880	COG3627	carbon phosphorus lyase activity
HHJ44_RS17885	COG3626	phosphonate metabolism
HHJ44_RS17890	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HHJ44_RS17895	COG3624	Phosphonate C-P lyase system protein PhnG
HHJ44_RS17900	COG2188	Transcriptional regulator
HHJ44_RS17905	COG3639	organic phosphonate transmembrane transporter activity
HHJ44_RS17910	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HHJ44_RS17920	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HHJ44_RS17925	COG2824	Alkylphosphonate utilization operon protein PhnA
HHJ44_RS17940	COG0477	Major facilitator Superfamily
HHJ44_RS17950	COG0642	Histidine kinase
HHJ44_RS17955	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS17960	COG2194	sulfuric ester hydrolase activity
HHJ44_RS17965	COG0531	amino acid
HHJ44_RS17970	COG2207	Transcriptional regulator
HHJ44_RS17975	COG1982	Orn Lys Arg decarboxylase major
HHJ44_RS17980	COG2169	Transcriptional regulator
HHJ44_RS17985	COG1486	melibiose metabolic process
HHJ44_RS17990	COG3647	Membrane
HHJ44_RS17995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ44_RS17995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HHJ44_RS18000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HHJ44_RS18005	COG4565	transcriptional regulatory protein
HHJ44_RS18010	COG3290	protein histidine kinase activity
HHJ44_RS18015	COG3592	Divergent 4Fe-4S mono-cluster
HHJ44_RS18020	COG2388	GCN5-related N-acetyl-transferase
HHJ44_RS18035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HHJ44_RS18040	COG3104	oligopeptide transport
HHJ44_RS18045	COG1982	Orn Lys Arg decarboxylase major
HHJ44_RS18050	COG0531	amino acid
HHJ44_RS18055	COG3710	Transcriptional regulator
HHJ44_RS18090	COG2003	Belongs to the UPF0758 family
HHJ44_RS18125	COG3596	GTP binding
HHJ44_RS18180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHJ44_RS18185	COG2207	Transcriptional regulator
HHJ44_RS18190	COG2972	Histidine kinase
HHJ44_RS18195	COG3344	reverse transcriptase
HHJ44_RS18210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHJ44_RS18215	COG1882	Formate acetyltransferase
HHJ44_RS18220	COG0693	protein deglycase activity
HHJ44_RS18230	COG1012	belongs to the aldehyde dehydrogenase family
HHJ44_RS18265	COG4820	ethanolamine utilization protein (EutJ)
HHJ44_RS18270	COG4869	propanediol catabolic process
HHJ44_RS18295	COG2831	hemolysin activation secretion protein
HHJ44_RS18350	COG0604	alcohol dehydrogenase
HHJ44_RS18360	COG0531	amino acid
HHJ44_RS18365	COG1982	Orn Lys Arg decarboxylase major
HHJ44_RS18370	COG0531	amino acid
HHJ44_RS18410	COG1309	transcriptional regulator
HHJ44_RS18425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HHJ44_RS18430	COG1027	Aspartate ammonia-lyase
HHJ44_RS18435	COG3030	protein affecting phage T7 exclusion by the F plasmid
HHJ44_RS18440	COG0531	amino acid
HHJ44_RS18465	COG1509	lysine 2,3-aminomutase activity
HHJ44_RS18475	COG5510	response to toxic substance
HHJ44_RS18480	COG5510	response to toxic substance
HHJ44_RS18485	COG2076	Multidrug Resistance protein
HHJ44_RS18490	COG3040	lipid binding
HHJ44_RS18495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HHJ44_RS18510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HHJ44_RS18515	COG1053	succinate dehydrogenase
HHJ44_RS18525	COG0531	amino acid
HHJ44_RS18540	COG3264	Mechanosensitive ion channel
HHJ44_RS18540	COG1511	domain protein
HHJ44_RS18580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HHJ44_RS18585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HHJ44_RS18585	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHJ44_RS18590	COG0802	atpase or kinase
HHJ44_RS18595	COG0860	N-Acetylmuramoyl-L-alanine amidase
HHJ44_RS18615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHJ44_RS18620	COG0330	HflC and HflK could
HHJ44_RS18625	COG0330	HflC and HflK could
HHJ44_RS18630	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HHJ44_RS18645	COG0557	exoribonuclease II activity
HHJ44_RS18650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHJ44_RS18655	COG3789	protein conserved in bacteria
HHJ44_RS18660	COG1842	Phage shock protein A
HHJ44_RS18670	COG3766	membrane
HHJ44_RS18675	COG5463	Belongs to the UPF0441 family
HHJ44_RS18680	COG0754	glutathionylspermidine amidase activity
HHJ44_RS18685	COG1960	acyl-CoA dehydrogenase activity
HHJ44_RS18695	COG3650	response to hydrogen peroxide
HHJ44_RS18700	COG1073	alpha beta
HHJ44_RS18715	COG3037	sugar-specific permease SgaT UlaA
HHJ44_RS18720	COG3414	Phosphotransferase system galactitol-specific IIB component
HHJ44_RS18760	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHJ44_RS18780	COG2271	Major facilitator Superfamily
HHJ44_RS18785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HHJ44_RS18790	COG4670	ketone body catabolic process
HHJ44_RS18795	COG1024	Enoyl-CoA hydratase
HHJ44_RS18810	COG1309	transcriptional regulator
HHJ44_RS18815	COG3061	Opacity-associated protein A
HHJ44_RS18820	COG0545	Peptidyl-prolyl cis-trans isomerase
HHJ44_RS18825	COG1113	amino acid transport
HHJ44_RS18835	COG0697	spore germination
HHJ44_RS18840	COG0702	epimerase
HHJ44_RS18845	COG1733	regulation of RNA biosynthetic process
HHJ44_RS18850	COG0737	Belongs to the 5'-nucleotidase family
HHJ44_RS18855	COG1218	3'(2'),5'-bisphosphate nucleotidase
HHJ44_RS18860	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HHJ44_RS18870	COG1253	flavin adenine dinucleotide binding
HHJ44_RS18880	COG0729	surface antigen
HHJ44_RS18885	COG2911	Protein conserved in bacteria
HHJ44_RS18890	COG2105	PFAM AIG2 family protein
HHJ44_RS18895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HHJ44_RS18900	COG1879	ABC-type sugar transport system periplasmic component
HHJ44_RS18905	COG1129	ABC transporter
HHJ44_RS18910	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ44_RS18915	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ44_RS18925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HHJ44_RS18935	COG0312	modulator of DNA gyrase
HHJ44_RS18940	COG3783	Cytochrome b(562)
HHJ44_RS18945	COG0602	queuosine metabolic process
HHJ44_RS18950	COG1328	CTP reductase activity
HHJ44_RS18955	COG0366	Alpha amylase catalytic
HHJ44_RS18960	COG1263	PTS System
HHJ44_RS18960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS18965	COG1609	Transcriptional regulator
HHJ44_RS18975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HHJ44_RS18980	COG0251	oxidation-reduction process
HHJ44_RS19000	COG1438	arginine binding
HHJ44_RS19005	COG1288	antiporter activity
HHJ44_RS19010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHJ44_RS19015	COG0549	Belongs to the carbamate kinase family
HHJ44_RS19025	COG2731	YhcH YjgK YiaL family protein
HHJ44_RS19030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHJ44_RS19035	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HHJ44_RS19040	COG0456	acetyltransferase
HHJ44_RS19050	COG0525	valine-tRNA ligase activity
HHJ44_RS19055	COG2927	DNA polymerase III (CHI subunit)
HHJ44_RS19065	COG0795	lipopolysaccharide-transporting ATPase activity
HHJ44_RS19070	COG0795	lipopolysaccharide-transporting ATPase activity
HHJ44_RS19075	COG0433	COG0433 Predicted ATPase
HHJ44_RS19080	COG1609	Transcriptional regulator
HHJ44_RS19085	COG2610	gluconate transmembrane transporter activity
HHJ44_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS19095	COG1063	alcohol dehydrogenase
HHJ44_RS19100	COG3265	gluconokinase activity
HHJ44_RS19105	COG1064	alcohol dehydrogenase
HHJ44_RS19125	COG4227	nucleotidyltransferase activity
HHJ44_RS19160	COG3335	DDE superfamily endonuclease
HHJ44_RS19175	COG3177	Filamentation induced by cAMP protein fic
HHJ44_RS19190	COG1737	Transcriptional regulator
HHJ44_RS19195	COG2190	(PTS) system
HHJ44_RS19195	COG1263	PTS System
HHJ44_RS19195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS19200	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HHJ44_RS19225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS19235	COG3037	sugar-specific permease SgaT UlaA
HHJ44_RS19250	COG0738	Major facilitator superfamily
HHJ44_RS19260	COG1349	DNA-binding transcription factor activity
HHJ44_RS19280	COG4372	Transposase
HHJ44_RS19285	COG3436	PFAM IS66 Orf2 family protein
HHJ44_RS19340	COG3468	outer membrane autotransporter barrel domain protein
HHJ44_RS19365	COG2003	Belongs to the UPF0758 family
HHJ44_RS19430	COG1401	restriction endodeoxyribonuclease activity
HHJ44_RS19435	COG1215	transferase activity, transferring glycosyl groups
HHJ44_RS19440	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HHJ44_RS19450	COG0235	Class ii aldolase
HHJ44_RS19460	COG2390	Transcriptional regulator
HHJ44_RS19465	COG2610	gluconate transmembrane transporter activity
HHJ44_RS19470	COG0129	dihydroxy-acid dehydratase activity
HHJ44_RS19475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHJ44_RS19480	COG1414	Transcriptional regulator
HHJ44_RS19485	COG1349	DNA-binding transcription factor activity
HHJ44_RS19490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HHJ44_RS19495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS19500	COG0434	BtpA family
HHJ44_RS19505	COG3775	system Galactitol-specific IIC component
HHJ44_RS19510	COG3414	Phosphotransferase system galactitol-specific IIB component
HHJ44_RS19515	COG1363	Peptidase, m42
HHJ44_RS19525	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HHJ44_RS19530	COG3153	acetyltransferase
HHJ44_RS19555	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HHJ44_RS19560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HHJ44_RS19565	COG0582	viral genome integration into host DNA
HHJ44_RS19570	COG4974	Belongs to the 'phage' integrase family
HHJ44_RS19580	COG3539	Fimbrial protein
HHJ44_RS19585	COG3121	Chaperone
HHJ44_RS19590	COG3188	usher protein
HHJ44_RS19595	COG3539	Fimbrial protein
HHJ44_RS19600	COG3539	Fimbrial protein
HHJ44_RS19605	COG3539	Fimbrial protein
HHJ44_RS19610	COG2610	gluconate transmembrane transporter activity
HHJ44_RS19620	COG0246	Mannitol dehydrogenase
HHJ44_RS19625	COG2186	Transcriptional regulator
HHJ44_RS19650	COG0583	DNA-binding transcription factor activity
HHJ44_RS19655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHJ44_RS19660	COG0700	Nucleoside recognition
HHJ44_RS19665	COG3366	ferrous iron transmembrane transporter activity
HHJ44_RS19675	COG0477	Major facilitator Superfamily
HHJ44_RS19690	COG1924	4 iron, 4 sulfur cluster binding
HHJ44_RS19695	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HHJ44_RS19700	COG2733	membrane
HHJ44_RS19705	COG2814	Major facilitator Superfamily
HHJ44_RS19730	COG0523	cobalamin synthesis protein
HHJ44_RS19735	COG2879	small protein
HHJ44_RS19740	COG1966	Carbon starvation protein
HHJ44_RS19745	COG0840	transmembrane signaling receptor activity
HHJ44_RS19755	COG1802	Transcriptional regulator
HHJ44_RS19760	COG1063	alcohol dehydrogenase
HHJ44_RS19775	COG1484	DNA-dependent DNA replication
HHJ44_RS19790	COG2966	Psort location CytoplasmicMembrane, score
HHJ44_RS19795	COG2197	response regulator
HHJ44_RS19800	COG2197	response regulator
HHJ44_RS19805	COG4114	ferric iron reductase
HHJ44_RS19835	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HHJ44_RS19840	COG0456	acetyltransferase
HHJ44_RS19845	COG1011	Hydrolase
HHJ44_RS20120	COG2823	Periplasmic or secreted lipoprotein
HHJ44_RS20130	COG4667	esterase of the alpha-beta hydrolase superfamily
HHJ44_RS20135	COG0084	hydrolase, TatD family'
HHJ44_RS20140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHJ44_RS20145	COG1328	CTP reductase activity
HHJ44_RS20180	COG3726	membrane protein affecting hemolysin expression
HHJ44_RS20185	COG0560	Phosphoserine phosphatase
HHJ44_RS20190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHJ44_RS20195	COG1056	cytidyltransferase-related domain
HHJ44_RS20195	COG3172	ATPase kinase involved in NAD metabolism
HHJ44_RS20200	COG0488	(ABC) transporter
HHJ44_RS20205	COG0741	lytic transglycosylase activity
HHJ44_RS20225	COG3708	Transcriptional regulator
HHJ44_RS20225	COG2207	Transcriptional regulator
HHJ44_RS20230	COG3045	CreA protein
HHJ44_RS20235	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS20240	COG2205	protein histidine kinase activity
HHJ44_RS20245	COG4452	Inner membrane protein CreD
HHJ44_RS20250	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS20260	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HHJ44_RS20270	COG0527	aspartate kinase activity
HHJ44_RS20270	COG0460	homoserine dehydrogenase
HHJ44_RS20280	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HHJ44_RS20295	COG1115	amino acid carrier protein
HHJ44_RS20305	COG0521	Mo-molybdopterin cofactor biosynthetic process
HHJ44_RS20310	COG1584	GPR1 FUN34 yaaH family protein
HHJ44_RS20315	COG4735	regulation of single-species biofilm formation
HHJ44_RS20345	COG3119	arylsulfatase activity
HHJ44_RS20360	COG0583	DNA-binding transcription factor activity
HHJ44_RS20375	COG0196	riboflavin kinase activity
HHJ44_RS20390	COG1047	Peptidyl-prolyl cis-trans
HHJ44_RS20415	COG0505	Belongs to the CarA family
HHJ44_RS20420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HHJ44_RS20475	COG0644	oxidoreductase
HHJ44_RS20480	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HHJ44_RS20485	COG2271	Major facilitator Superfamily
HHJ44_RS20500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHJ44_RS20535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HHJ44_RS20540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HHJ44_RS20550	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HHJ44_RS20555	COG0564	pseudouridine synthase activity
HHJ44_RS20565	COG0417	DNA replication proofreading
HHJ44_RS20570	COG0235	Class ii aldolase
HHJ44_RS20585	COG4977	sequence-specific DNA binding
HHJ44_RS20600	COG0586	Pfam SNARE associated Golgi protein
HHJ44_RS20610	COG1178	ABC-type Fe3 transport system permease component
HHJ44_RS20615	COG4143	(ABC) transporter
HHJ44_RS20655	COG0583	DNA-binding transcription factor activity
HHJ44_RS20660	COG0028	Belongs to the TPP enzyme family
HHJ44_RS20665	COG0440	acetolactate synthase activity
HHJ44_RS20675	COG1609	Transcriptional regulator
HHJ44_RS20690	COG3116	cell division
HHJ44_RS20695	COG0768	penicillin binding
HHJ44_RS20700	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHJ44_RS20705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HHJ44_RS20720	COG0772	Belongs to the SEDS family
HHJ44_RS20735	COG1181	Belongs to the D-alanine--D-alanine ligase family
HHJ44_RS20740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HHJ44_RS20745	COG0849	cell division
HHJ44_RS20750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHJ44_RS20770	COG0494	nUDIX hydrolase
HHJ44_RS20785	COG0237	dephospho-CoA kinase activity
HHJ44_RS20795	COG1459	type II secretion system
HHJ44_RS20800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHJ44_RS20805	COG4969	Belongs to the N-Me-Phe pilin family
HHJ44_RS20810	COG0157	Belongs to the NadC ModD family
HHJ44_RS20815	COG3023	N-Acetylmuramoyl-L-alanine amidase
HHJ44_RS20820	COG3725	Membrane protein required for beta-lactamase induction
HHJ44_RS20825	COG1113	amino acid transport
HHJ44_RS20830	COG3157	Type VI secretion system effector, Hcp
HHJ44_RS20860	COG2186	Transcriptional regulator
HHJ44_RS20865	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HHJ44_RS20870	COG0508	dehydrogenase complex catalyzes the overall conversion of
HHJ44_RS20875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHJ44_RS20880	COG3064	Membrane
HHJ44_RS20885	COG1049	propionate catabolic process, 2-methylcitrate cycle
HHJ44_RS20910	COG2132	Multicopper oxidase
HHJ44_RS20915	COG4993	Dehydrogenase
HHJ44_RS20920	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HHJ44_RS20925	COG0288	reversible hydration of carbon dioxide
HHJ44_RS20930	COG1131	(ABC) transporter
HHJ44_RS20935	COG0842	Transport permease protein
HHJ44_RS20940	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HHJ44_RS20945	COG0726	polysaccharide deacetylase
HHJ44_RS20955	COG5464	transposase or invertase
HHJ44_RS20970	COG3539	Fimbrial protein
HHJ44_RS20975	COG3539	Fimbrial protein
HHJ44_RS20980	COG3539	Fimbrial protein
HHJ44_RS20985	COG3539	Fimbrial protein
HHJ44_RS20990	COG3188	usher protein
HHJ44_RS20995	COG3121	Chaperone
HHJ44_RS21000	COG3539	Fimbrial protein
HHJ44_RS21005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHJ44_RS21010	COG0617	tRNA 3'-terminal CCA addition
HHJ44_RS21015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHJ44_RS21020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HHJ44_RS21030	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HHJ44_RS21035	COG1643	Atp-dependent helicase
HHJ44_RS21040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HHJ44_RS21045	COG4774	siderophore transport
HHJ44_RS21050	COG1120	ATPase activity
HHJ44_RS21055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HHJ44_RS21060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ44_RS21085	COG2860	membrane
HHJ44_RS21090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HHJ44_RS21105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHJ44_RS21110	COG3835	regulator
HHJ44_RS21130	COG0024	Methionine aminopeptidase
HHJ44_RS21155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HHJ44_RS21160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHJ44_RS21165	COG0575	Belongs to the CDS family
HHJ44_RS21170	COG0750	zinc metalloprotease
HHJ44_RS21180	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HHJ44_RS21210	COG0587	DNA-directed DNA polymerase activity
HHJ44_RS21225	COG0346	lactoylglutathione lyase activity
HHJ44_RS21230	COG0037	tRNA processing
HHJ44_RS21235	COG4568	rho-dependent transcription termination
HHJ44_RS21245	COG4681	YaeQ
HHJ44_RS21250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHJ44_RS21255	COG3015	lipoprotein NlpE involved in copper resistance
HHJ44_RS21260	COG0791	NLP P60 protein
HHJ44_RS21270	COG1720	tRNA m6t6A37 methyltransferase activity
HHJ44_RS21280	COG1464	Belongs to the NlpA lipoprotein family
HHJ44_RS21285	COG2011	ABC-type metal ion transport system permease component
HHJ44_RS21290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHJ44_RS21295	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HHJ44_RS21325	COG0656	L-ascorbic acid biosynthetic process
HHJ44_RS21330	COG0583	DNA-binding transcription factor activity
HHJ44_RS21340	COG2226	methyltransferase
HHJ44_RS21345	COG0741	lytic transglycosylase activity
HHJ44_RS21345	COG1388	LysM domain
HHJ44_RS21355	COG2226	methyltransferase
HHJ44_RS21365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HHJ44_RS21500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HHJ44_RS21510	COG1960	acyl-CoA dehydrogenase activity
HHJ44_RS21520	COG0121	glutamine amidotransferase
HHJ44_RS21525	COG3034	peptidoglycan biosynthetic process
HHJ44_RS21530	COG0791	NLP P60 protein
HHJ44_RS21535	COG1943	Transposase
HHJ44_RS21560	COG2161	toxin-antitoxin pair type II binding
HHJ44_RS21570	COG0454	-acetyltransferase
HHJ44_RS21575	COG1690	Belongs to the RtcB family
HHJ44_RS21580	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHJ44_RS21585	COG2195	Cleaves the N-terminal amino acid of tripeptides
HHJ44_RS21605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHJ44_RS21625	COG0582	viral genome integration into host DNA
HHJ44_RS21655	COG3477	response to acidic pH
HHJ44_RS21665	COG0727	PFAM Uncharacterised protein family (UPF0153)
HHJ44_RS21720	COG1902	pentaerythritol trinitrate reductase activity
HHJ44_RS21725	COG1073	alpha beta
HHJ44_RS21730	COG0583	DNA-binding transcription factor activity
HHJ44_RS21740	COG0667	Aldo Keto reductase
HHJ44_RS21745	COG0656	L-ascorbic acid biosynthetic process
HHJ44_RS21750	COG1388	LysM domain
HHJ44_RS21755	COG2207	Transcriptional regulator
HHJ44_RS21755	COG3708	Transcriptional regulator
HHJ44_RS21760	COG0656	L-ascorbic acid biosynthetic process
HHJ44_RS21765	COG3059	membrane
HHJ44_RS21775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHJ44_RS21780	COG2207	Transcriptional regulator
HHJ44_RS21785	COG0247	lactate metabolic process
HHJ44_RS21790	COG1139	Iron-sulfur cluster binding protein
HHJ44_RS21795	COG1556	Lactate utilization protein
HHJ44_RS21815	COG3468	outer membrane autotransporter barrel domain protein
HHJ44_RS21835	COG2771	luxR family
HHJ44_RS21835	COG2200	EAL domain
HHJ44_RS21840	COG0582	viral genome integration into host DNA
HHJ44_RS21860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HHJ44_RS21865	COG2771	luxR family
HHJ44_RS21865	COG2200	EAL domain
HHJ44_RS21870	COG0583	DNA-binding transcription factor activity
HHJ44_RS21880	COG0666	response to abiotic stimulus
HHJ44_RS21890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ44_RS21895	COG1304	FMN binding
HHJ44_RS21900	COG0549	Belongs to the carbamate kinase family
HHJ44_RS21905	COG0402	S-adenosylhomocysteine deaminase activity
HHJ44_RS21915	COG1879	ABC-type sugar transport system periplasmic component
HHJ44_RS21920	COG1129	ABC transporter
HHJ44_RS21925	COG1172	Belongs to the binding-protein-dependent transport system permease family
HHJ44_RS21935	COG1064	alcohol dehydrogenase
HHJ44_RS21945	COG1280	lysine exporter protein (LysE YggA)
HHJ44_RS21960	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HHJ44_RS21965	COG0372	Belongs to the citrate synthase family
HHJ44_RS21970	COG2079	MmgE PrpD family protein
HHJ44_RS21975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HHJ44_RS21980	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HHJ44_RS21985	COG0402	S-adenosylhomocysteine deaminase activity
HHJ44_RS21990	COG0110	maltose O-acetyltransferase activity
HHJ44_RS21995	COG2223	nitrite transmembrane transporter activity
HHJ44_RS22005	COG1609	Transcriptional regulator
HHJ44_RS22015	COG3122	Protein conserved in bacteria
HHJ44_RS22045	COG1215	transferase activity, transferring glycosyl groups
HHJ44_RS22050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HHJ44_RS22055	COG4521	taurine ABC transporter
HHJ44_RS22065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HHJ44_RS22070	COG2175	clavaminate synthase activity
HHJ44_RS22075	COG0113	porphobilinogen synthase activity
HHJ44_RS22080	COG3468	outer membrane autotransporter barrel domain protein
HHJ44_RS22085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HHJ44_RS22090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HHJ44_RS22095	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HHJ44_RS22115	COG1181	Belongs to the D-alanine--D-alanine ligase family
HHJ44_RS22130	COG1785	Belongs to the alkaline phosphatase family
HHJ44_RS22140	COG3706	GGDEF domain
HHJ44_RS22145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHJ44_RS22165	COG4126	flavin adenine dinucleotide binding
HHJ44_RS22190	COG1940	carbohydrate kinase activity
HHJ44_RS22195	COG2814	Major facilitator Superfamily
HHJ44_RS22200	COG0419	ATPase involved in DNA repair
HHJ44_RS22205	COG0420	3'-5' exonuclease activity
HHJ44_RS22210	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS22215	COG5002	protein histidine kinase activity
HHJ44_RS22220	COG1114	Component of the transport system for branched-chain amino acids
HHJ44_RS22225	COG1113	amino acid transport
HHJ44_RS22230	COG0366	Alpha amylase catalytic
HHJ44_RS22250	COG1862	Preprotein translocase
HHJ44_RS22255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHJ44_RS22260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHJ44_RS22265	COG1403	HNH endonuclease
HHJ44_RS22270	COG3248	Nucleoside-binding outer membrane protein
HHJ44_RS22275	COG4238	major outer membrane lipoprotein
HHJ44_RS22285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHJ44_RS22285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHJ44_RS22300	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HHJ44_RS22305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HHJ44_RS22310	COG0667	Aldo Keto reductase
HHJ44_RS22320	COG0142	geranyltranstransferase activity
HHJ44_RS22335	COG0693	protein deglycase activity
HHJ44_RS22340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHJ44_RS22350	COG2814	Major facilitator Superfamily
HHJ44_RS22360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HHJ44_RS22365	COG1845	cytochrome c oxidase, subunit III
HHJ44_RS22370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHJ44_RS22375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HHJ44_RS22380	COG2223	nitrite transmembrane transporter activity
HHJ44_RS22385	COG3056	Lipoprotein
HHJ44_RS22390	COG0271	Belongs to the BolA IbaG family
HHJ44_RS22410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HHJ44_RS22415	COG0776	regulation of translation
HHJ44_RS22420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HHJ44_RS22425	COG1555	photosystem II stabilization
HHJ44_RS22430	COG0824	Thioesterase
HHJ44_RS22440	COG4533	DNA binding
HHJ44_RS22450	COG1522	sequence-specific DNA binding
HHJ44_RS22455	COG1132	(ABC) transporter
HHJ44_RS22460	COG1132	(ABC) transporter
HHJ44_RS22465	COG0347	Belongs to the P(II) protein family
HHJ44_RS22470	COG0004	ammonium transporteR
HHJ44_RS22475	COG1946	Acyl-CoA thioesterase
HHJ44_RS22480	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HHJ44_RS22485	COG3695	enzyme binding
HHJ44_RS22495	COG5507	3-demethylubiquinone-9 3-methyltransferase
HHJ44_RS22500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HHJ44_RS22510	COG0110	maltose O-acetyltransferase activity
HHJ44_RS22525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ44_RS22530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ44_RS22535	COG1309	transcriptional regulator
HHJ44_RS22540	COG3264	Mechanosensitive ion channel
HHJ44_RS22540	COG1196	nuclear chromosome segregation
HHJ44_RS22550	COG3923	Primosomal replication protein n
HHJ44_RS22555	COG2832	Protein of unknown function (DUF454)
HHJ44_RS22565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHJ44_RS22600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHJ44_RS22605	COG4651	solute:proton antiporter activity
HHJ44_RS22605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HHJ44_RS22610	COG2223	nitrite transmembrane transporter activity
HHJ44_RS22615	COG0737	Belongs to the 5'-nucleotidase family
HHJ44_RS22630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHJ44_RS22635	COG3735	TraB family
HHJ44_RS22640	COG3549	Plasmid maintenance system killer
HHJ44_RS22645	COG3093	addiction module antidote protein HigA
HHJ44_RS22650	COG2217	Heavy metal translocating P-type atpase
HHJ44_RS22655	COG2066	Belongs to the glutaminase family
HHJ44_RS22660	COG0531	amino acid
HHJ44_RS22665	COG0789	Transcriptional regulator
HHJ44_RS22690	COG1585	Membrane protein implicated in regulation of membrane protease activity
HHJ44_RS22695	COG0330	HflC and HflK could
HHJ44_RS22700	COG4619	ABC transporter
HHJ44_RS22705	COG0390	transport system, permease component
HHJ44_RS22710	COG3118	belongs to the thioredoxin family
HHJ44_RS22715	COG0300	oxidoreductase activity
HHJ44_RS22720	COG2755	lipolytic protein G-D-S-L family
HHJ44_RS22725	COG4181	ATPase activity
HHJ44_RS22730	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HHJ44_RS22755	COG3960	tartronate-semialdehyde synthase activity
HHJ44_RS22760	COG3622	Belongs to the hyi family
HHJ44_RS22765	COG2084	Dehydrogenase
HHJ44_RS22770	COG1953	Uracil, thiamine, allantoin
HHJ44_RS22780	COG2233	PERMEase
HHJ44_RS22785	COG1929	Belongs to the glycerate kinase type-1 family
HHJ44_RS22790	COG3257	ureidoglycine aminohydrolase activity
HHJ44_RS22795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HHJ44_RS22800	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HHJ44_RS22805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ44_RS22810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ44_RS22820	COG0549	Belongs to the carbamate kinase family
HHJ44_RS22825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHJ44_RS22830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHJ44_RS22845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHJ44_RS22855	COG1988	membrane-bound metal-dependent
HHJ44_RS22860	COG2501	S4 domain
HHJ44_RS22880	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HHJ44_RS22885	COG0500	methyltransferase
HHJ44_RS22890	COG4571	Outer membrane protease
HHJ44_RS22900	COG4783	chaperone-mediated protein folding
HHJ44_RS22905	COG1215	transferase activity, transferring glycosyl groups
HHJ44_RS22910	COG5002	protein histidine kinase activity
HHJ44_RS22915	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS22920	COG1538	Outer membrane efflux protein
HHJ44_RS22925	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ44_RS22930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHJ44_RS22935	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHJ44_RS22940	COG1113	amino acid transport
HHJ44_RS22945	COG0668	transmembrane transport
HHJ44_RS22950	COG0778	Nitroreductase
HHJ44_RS22955	COG2315	Protein conserved in bacteria
HHJ44_RS22975	COG2977	Belongs to the P-Pant transferase superfamily
HHJ44_RS22980	COG4771	TonB-dependent receptor
HHJ44_RS22985	COG2382	esterase
HHJ44_RS22990	COG3251	PFAM MbtH domain protein
HHJ44_RS23000	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HHJ44_RS23005	COG1120	ATPase activity
HHJ44_RS23010	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ44_RS23015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHJ44_RS23025	COG4592	Periplasmic binding protein
HHJ44_RS23030	COG1169	isochorismate synthase
HHJ44_RS23035	COG1021	2,3-dihydroxybenzoate-AMP ligase
HHJ44_RS23040	COG3433	isochorismatase activity
HHJ44_RS23040	COG1535	isochorismatase
HHJ44_RS23045	COG1028	Short-chain dehydrogenase reductase Sdr
HHJ44_RS23050	COG2050	protein possibly involved in aromatic compounds catabolism
HHJ44_RS23055	COG1966	Carbon starvation protein
HHJ44_RS23060	COG2879	small protein
HHJ44_RS23065	COG0371	Dehydrogenase
HHJ44_RS23070	COG0436	Aminotransferase
HHJ44_RS23075	COG1475	DNA binding
HHJ44_RS23080	COG3969	phosphoadenosine phosphosulfate
HHJ44_RS23085	COG0583	DNA-binding transcription factor activity
HHJ44_RS23090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HHJ44_RS23095	COG0450	alkyl hydroperoxide reductase
HHJ44_RS23100	COG3634	alkyl hydroperoxide reductase activity
HHJ44_RS23105	COG0589	response to stress
HHJ44_RS23110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HHJ44_RS23115	COG3719	Belongs to the RNase T2 family
HHJ44_RS23120	COG0471	metal ion transport
HHJ44_RS23135	COG3051	citrate lyase alpha subunit
HHJ44_RS23140	COG2301	Belongs to the HpcH HpaI aldolase family
HHJ44_RS23150	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HHJ44_RS23155	COG3290	protein histidine kinase activity
HHJ44_RS23160	COG4565	transcriptional regulatory protein
HHJ44_RS23165	COG3069	C4-dicarboxylate transmembrane transporter activity
HHJ44_RS23185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HHJ44_RS23190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHJ44_RS23210	COG1686	Belongs to the peptidase S11 family
HHJ44_RS23215	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HHJ44_RS23220	COG0772	Belongs to the SEDS family
HHJ44_RS23225	COG0768	penicillin binding
HHJ44_RS23235	COG0799	negative regulation of ribosome biogenesis
HHJ44_RS23240	COG0406	alpha-ribazole phosphatase activity
HHJ44_RS23250	COG1466	dna polymerase III delta subunit
HHJ44_RS23265	COG2888	peptidyl-tyrosine sulfation
HHJ44_RS23275	COG1126	abc transporter atp-binding protein
HHJ44_RS23280	COG0765	amino acid transport
HHJ44_RS23285	COG0765	amino acid transport
HHJ44_RS23290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ44_RS23300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HHJ44_RS23305	COG4535	Mg2 and Co2 transporter CorC
HHJ44_RS23315	COG1702	phosphate starvation-inducible protein PhoH
HHJ44_RS23325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HHJ44_RS23365	COG0367	asparagine synthase
HHJ44_RS23370	COG0647	UMP catabolic process
HHJ44_RS23375	COG1846	Transcriptional regulator
HHJ44_RS23375	COG1940	carbohydrate kinase activity
HHJ44_RS23380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHJ44_RS23390	COG2190	(PTS) system
HHJ44_RS23390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHJ44_RS23390	COG1263	PTS System
HHJ44_RS23415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHJ44_RS23420	COG1454	alcohol dehydrogenase
HHJ44_RS23425	COG3395	kinase activity
HHJ44_RS23430	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HHJ44_RS23435	COG1349	DNA-binding transcription factor activity
HHJ44_RS23455	COG0735	belongs to the Fur family
HHJ44_RS23465	COG0716	FMN binding
HHJ44_RS23475	COG0596	Alpha beta hydrolase
HHJ44_RS23480	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HHJ44_RS23485	COG0033	Phosphoglucomutase
HHJ44_RS23490	COG0531	amino acid
HHJ44_RS23495	COG1982	Orn Lys Arg decarboxylase major
HHJ44_RS23505	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS23510	COG2205	protein histidine kinase activity
HHJ44_RS23540	COG3272	Protein of unknown function (DUF1722)
HHJ44_RS23545	COG0415	Belongs to the DNA photolyase family
HHJ44_RS23555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHJ44_RS23560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HHJ44_RS23565	COG1984	allophanate hydrolase subunit 2
HHJ44_RS23580	COG3180	Ammonia monooxygenase
HHJ44_RS23585	COG3539	Fimbrial protein
HHJ44_RS23590	COG0372	Belongs to the citrate synthase family
HHJ44_RS23600	COG2009	succinate dehydrogenase
HHJ44_RS23605	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HHJ44_RS23610	COG1053	succinate dehydrogenase
HHJ44_RS23615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HHJ44_RS23620	COG0567	Dehydrogenase, E1 component
HHJ44_RS23625	COG0508	dehydrogenase complex catalyzes the overall conversion of
HHJ44_RS23635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHJ44_RS23645	COG1271	oxidase subunit
HHJ44_RS23650	COG1294	oxidase, subunit
HHJ44_RS23655	COG4890	Cyd operon protein YbgT
HHJ44_RS23660	COG3790	cyd operon protein YbgE
HHJ44_RS23665	COG0824	Thioesterase
HHJ44_RS23670	COG0811	peptide transport
HHJ44_RS23675	COG0848	biopolymer transport protein
HHJ44_RS23680	COG3064	Membrane
HHJ44_RS23690	COG2885	chlorophyll binding
HHJ44_RS23695	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HHJ44_RS23740	COG3201	nicotinamide mononucleotide transporter
HHJ44_RS23745	COG1230	cation diffusion facilitator family transporter
HHJ44_RS23755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHJ44_RS23765	COG2017	converts alpha-aldose to the beta-anomer
HHJ44_RS23775	COG1085	galactose-1-phosphate uridylyltransferase
HHJ44_RS23780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HHJ44_RS23785	COG1119	ATPase activity
HHJ44_RS23790	COG3585	molybdate ion transport
HHJ44_RS23790	COG2005	Transcriptional regulator
HHJ44_RS23800	COG0725	ABC transporter, periplasmic molybdate-binding protein
HHJ44_RS23805	COG4149	molybdate abc transporter
HHJ44_RS23815	COG0561	phosphatase activity
HHJ44_RS23825	COG0583	DNA-binding transcription factor activity
HHJ44_RS23830	COG2828	Protein conserved in bacteria
HHJ44_RS23840	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHJ44_RS23845	COG4677	pectinesterase activity
HHJ44_RS23850	COG1881	PFAM PEBP family protein
HHJ44_RS23855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HHJ44_RS23870	COG2226	methyltransferase
HHJ44_RS23875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HHJ44_RS23885	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HHJ44_RS23895	COG0521	Mo-molybdopterin cofactor biosynthetic process
HHJ44_RS23905	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HHJ44_RS23910	COG0314	molybdopterin synthase activity
HHJ44_RS23915	COG0670	Belongs to the BI1 family
HHJ44_RS23920	COG0670	Belongs to the BI1 family
HHJ44_RS23925	COG0392	lysyltransferase activity
HHJ44_RS23930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHJ44_RS23935	COG3568	Endonuclease Exonuclease Phosphatase
HHJ44_RS23945	COG0842	Transport permease protein
HHJ44_RS23950	COG0842	Transport permease protein
HHJ44_RS23955	COG1131	(ABC) transporter
HHJ44_RS23965	COG1309	transcriptional regulator
HHJ44_RS23970	COG0513	Belongs to the DEAD box helicase family
HHJ44_RS23980	COG1199	ATP-dependent helicase activity
HHJ44_RS23985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHJ44_RS23990	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HHJ44_RS24005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HHJ44_RS24030	COG0668	transmembrane transport
HHJ44_RS24035	COG1126	abc transporter atp-binding protein
HHJ44_RS24040	COG0765	amino acid transport
HHJ44_RS24045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HHJ44_RS24055	COG5006	permease, DMT superfamily
HHJ44_RS24065	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HHJ44_RS24070	COG2194	sulfuric ester hydrolase activity
HHJ44_RS24080	COG1321	iron dependent repressor
HHJ44_RS24085	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHJ44_RS24090	COG1376	ErfK ybiS ycfS ynhG family protein
HHJ44_RS24095	COG0488	(ABC) transporter
HHJ44_RS24100	COG0561	phosphatase activity
HHJ44_RS24105	COG1882	Formate acetyltransferase
HHJ44_RS24110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHJ44_RS24115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHJ44_RS24120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HHJ44_RS24125	COG0303	'Molybdopterin
HHJ44_RS24130	COG1446	asparaginase
HHJ44_RS24155	COG2200	EAL domain
HHJ44_RS24160	COG2199	diguanylate cyclase activity
HHJ44_RS24175	COG2133	pyrroloquinoline quinone binding
HHJ44_RS24180	COG0625	glutathione transferase activity
HHJ44_RS24185	COG1686	Belongs to the peptidase S11 family
HHJ44_RS24190	COG1349	DNA-binding transcription factor activity
HHJ44_RS24195	COG0671	phosphoesterase, PA-phosphatase related
HHJ44_RS24200	COG2814	Major facilitator Superfamily
HHJ44_RS24210	COG0561	phosphatase activity
HHJ44_RS24215	COG0738	Major facilitator superfamily
HHJ44_RS24220	COG3226	Transcriptional regulator
HHJ44_RS24260	COG3173	Aminoglycoside phosphotransferase
HHJ44_RS24280	COG3468	outer membrane autotransporter barrel domain protein
HHJ44_RS24315	COG1136	(ABC) transporter
HHJ44_RS24455	COG4771	TonB-dependent receptor
HHJ44_RS24495	COG0640	Transcriptional regulator
HHJ44_RS24500	COG0446	pyridine nucleotide-disulphide oxidoreductase
HHJ44_RS24565	COG1136	(ABC) transporter
HHJ44_RS24565	COG0577	efflux transmembrane transporter activity
HHJ44_RS24575	COG0577	efflux transmembrane transporter activity
HHJ44_RS24575	COG1136	(ABC) transporter
HHJ44_RS24590	COG0672	)-iron permease
HHJ44_RS24595	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HHJ44_RS24600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HHJ44_RS24760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HHJ44_RS24765	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HHJ44_RS24770	COG0745	RESPONSE REGULATOR receiver
HHJ44_RS24775	COG5002	protein histidine kinase activity
HHJ44_RS24795	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HHJ44_RS24945	COG1475	DNA binding
HHJ44_RS24980	COG3173	Aminoglycoside phosphotransferase
HHJ44_RS25020	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHJ44_RS25050	COG1278	Cold shock
HHJ44_RS25085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HHJ44_RS25195	COG5301	cellulose 1,4-beta-cellobiosidase activity
HHJ44_RS25240	COG3941	tape measure
HHJ44_RS25290	COG5492	domain, Protein
HHJ44_RS25290	COG4932	domain protein
HHJ44_RS25335	COG1475	DNA binding
HHJ44_RS25340	COG1475	DNA binding
HHJ44_RS25450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHJ44_RS25535	COG0328	RNA-DNA hybrid ribonuclease activity
HHJ44_RS25565	COG0237	dephospho-CoA kinase activity
HHJ44_RS25580	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHJ44_RS25590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHJ44_RS25595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides