locus-tag	class	description
CR916_RS00130	COG3657	addiction module killer protein
CR916_RS00220	COG3451	type IV secretory pathway VirB4
CR916_RS00250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CR916_RS00305	COG3504	Conjugal transfer protein
CR916_RS00330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CR916_RS00350	COG3547	Transposase (IS116 IS110 IS902 family)
CR916_RS00355	COG3547	Transposase (IS116 IS110 IS902 family)
CR916_RS00405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CR916_RS00420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CR916_RS00490	COG3436	PFAM IS66 Orf2 family protein
CR916_RS00500	COG3468	outer membrane autotransporter barrel domain protein
CR916_RS00520	COG3436	PFAM IS66 Orf2 family protein
CR916_RS00555	COG2274	protein secretion by the type I secretion system
CR916_RS00600	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CR916_RS00930	COG1846	Transcriptional regulator
CR916_RS00935	COG4725	Belongs to the MT-A70-like family
CR916_RS00940	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CR916_RS00950	COG1403	HNH endonuclease
CR916_RS01015	COG3772	lysozyme
CR916_RS01120	COG0604	alcohol dehydrogenase
CR916_RS01125	COG0305	Participates in initiation and elongation during chromosome replication
CR916_RS01130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CR916_RS01135	COG1448	Aminotransferase
CR916_RS01145	COG3700	Belongs to the class B bacterial acid phosphatase family
CR916_RS01150	COG0432	Pfam Uncharacterised protein family UPF0047
CR916_RS01155	COG2315	Protein conserved in bacteria
CR916_RS01160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CR916_RS01170	COG0629	single-stranded DNA binding
CR916_RS01200	COG2207	Transcriptional regulator
CR916_RS01205	COG0789	Transcriptional regulator
CR916_RS01225	COG2252	PERMEase
CR916_RS01230	COG0025	NhaP-type Na H and K H
CR916_RS01235	COG1357	PFAM Pentapeptide repeats (8 copies)
CR916_RS01245	COG3162	membrane
CR916_RS01250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CR916_RS01265	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CR916_RS01270	COG0437	4 iron, 4 sulfur cluster binding
CR916_RS01275	COG3301	Polysulphide reductase, NrfD
CR916_RS01280	COG1138	Cytochrome C-type biogenesis protein
CR916_RS01285	COG3088	subunit of a heme lyase
CR916_RS01290	COG4235	cytochrome complex assembly
CR916_RS01300	COG1301	dicarboxylic acid transport
CR916_RS01305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CR916_RS01320	COG1289	transmembrane transporter activity
CR916_RS01325	COG1566	PFAM secretion protein HlyD family protein
CR916_RS01340	COG0698	ribose 5-phosphate isomerase
CR916_RS01350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CR916_RS01355	COG0456	acetyltransferase
CR916_RS01360	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CR916_RS01365	COG3454	Phosphonate metabolism
CR916_RS01370	COG4778	phosphonate C-P lyase system protein PhnL
CR916_RS01375	COG4107	phosphonate C-P lyase system protein PhnK
CR916_RS01380	COG3627	carbon phosphorus lyase activity
CR916_RS01385	COG3626	phosphonate metabolism
CR916_RS01390	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CR916_RS01395	COG3624	Phosphonate C-P lyase system protein PhnG
CR916_RS01400	COG2188	Transcriptional regulator
CR916_RS01410	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CR916_RS01420	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CR916_RS01425	COG2824	Alkylphosphonate utilization operon protein PhnA
CR916_RS01435	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CR916_RS01445	COG0477	Major facilitator Superfamily
CR916_RS01455	COG0642	Histidine kinase
CR916_RS01460	COG0745	RESPONSE REGULATOR receiver
CR916_RS01465	COG2194	sulfuric ester hydrolase activity
CR916_RS01475	COG2207	Transcriptional regulator
CR916_RS01480	COG1982	Orn Lys Arg decarboxylase major
CR916_RS01485	COG2169	Transcriptional regulator
CR916_RS01490	COG1486	melibiose metabolic process
CR916_RS01510	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CR916_RS01510	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CR916_RS01515	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CR916_RS01525	COG4565	transcriptional regulatory protein
CR916_RS01530	COG3290	protein histidine kinase activity
CR916_RS01535	COG3592	Divergent 4Fe-4S mono-cluster
CR916_RS01560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CR916_RS01565	COG3104	oligopeptide transport
CR916_RS01570	COG1982	Orn Lys Arg decarboxylase major
CR916_RS01575	COG0531	amino acid
CR916_RS01585	COG3710	Transcriptional regulator
CR916_RS01890	COG1309	transcriptional regulator
CR916_RS01905	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CR916_RS01910	COG1027	Aspartate ammonia-lyase
CR916_RS01915	COG3030	protein affecting phage T7 exclusion by the F plasmid
CR916_RS01920	COG0531	amino acid
CR916_RS01945	COG1509	lysine 2,3-aminomutase activity
CR916_RS01955	COG5510	response to toxic substance
CR916_RS01960	COG5510	response to toxic substance
CR916_RS01965	COG2076	Multidrug Resistance protein
CR916_RS01970	COG3040	lipid binding
CR916_RS01975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CR916_RS01990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CR916_RS01995	COG1053	succinate dehydrogenase
CR916_RS02020	COG1511	domain protein
CR916_RS02020	COG3264	Mechanosensitive ion channel
CR916_RS02060	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CR916_RS02065	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CR916_RS02065	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CR916_RS02070	COG0802	atpase or kinase
CR916_RS02075	COG0860	N-Acetylmuramoyl-L-alanine amidase
CR916_RS02095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CR916_RS02100	COG0330	HflC and HflK could
CR916_RS02105	COG0330	HflC and HflK could
CR916_RS02110	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CR916_RS02125	COG0557	exoribonuclease II activity
CR916_RS02130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CR916_RS02140	COG3789	protein conserved in bacteria
CR916_RS02145	COG1842	Phage shock protein A
CR916_RS02150	COG2826	transposase and inactivated derivatives, IS30 family
CR916_RS02165	COG3766	membrane
CR916_RS02175	COG0754	glutathionylspermidine amidase activity
CR916_RS02180	COG1960	acyl-CoA dehydrogenase activity
CR916_RS02190	COG3650	response to hydrogen peroxide
CR916_RS02195	COG1073	alpha beta
CR916_RS02210	COG3037	sugar-specific permease SgaT UlaA
CR916_RS02240	COG3477	response to acidic pH
CR916_RS02260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CR916_RS02290	COG2271	Major facilitator Superfamily
CR916_RS02295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CR916_RS02300	COG4670	ketone body catabolic process
CR916_RS02305	COG1024	Enoyl-CoA hydratase
CR916_RS02320	COG1309	transcriptional regulator
CR916_RS02325	COG3061	Opacity-associated protein A
CR916_RS02335	COG0545	Peptidyl-prolyl cis-trans isomerase
CR916_RS02340	COG1113	amino acid transport
CR916_RS02350	COG0697	spore germination
CR916_RS02355	COG0702	epimerase
CR916_RS02360	COG1733	regulation of RNA biosynthetic process
CR916_RS02365	COG0737	Belongs to the 5'-nucleotidase family
CR916_RS02370	COG1218	3'(2'),5'-bisphosphate nucleotidase
CR916_RS02375	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CR916_RS02385	COG1253	flavin adenine dinucleotide binding
CR916_RS02395	COG0729	surface antigen
CR916_RS02400	COG2911	Protein conserved in bacteria
CR916_RS02405	COG2105	PFAM AIG2 family protein
CR916_RS02410	COG2336	PFAM SpoVT AbrB
CR916_RS02415	COG2337	Toxic component of a toxin-antitoxin (TA) module
CR916_RS02420	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CR916_RS02435	COG1172	Belongs to the binding-protein-dependent transport system permease family
CR916_RS02440	COG1172	Belongs to the binding-protein-dependent transport system permease family
CR916_RS02450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CR916_RS02460	COG0312	modulator of DNA gyrase
CR916_RS02465	COG3783	Cytochrome b(562)
CR916_RS02470	COG0602	queuosine metabolic process
CR916_RS02475	COG1328	CTP reductase activity
CR916_RS02480	COG0366	Alpha amylase catalytic
CR916_RS02485	COG1263	PTS System
CR916_RS02485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS02490	COG1609	Transcriptional regulator
CR916_RS02500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CR916_RS02505	COG0251	oxidation-reduction process
CR916_RS02530	COG0251	oxidation-reduction process
CR916_RS02535	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS02540	COG1309	transcriptional regulator
CR916_RS02560	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CR916_RS02565	COG0456	acetyltransferase
CR916_RS02570	COG4269	membrane
CR916_RS02575	COG0525	valine-tRNA ligase activity
CR916_RS02580	COG2927	DNA polymerase III (CHI subunit)
CR916_RS02590	COG0795	lipopolysaccharide-transporting ATPase activity
CR916_RS02595	COG0795	lipopolysaccharide-transporting ATPase activity
CR916_RS02605	COG1064	alcohol dehydrogenase
CR916_RS02615	COG0582	viral genome integration into host DNA
CR916_RS02650	COG5532	Uncharacterized conserved protein (DUF2303)
CR916_RS02655	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CR916_RS02680	COG0582	viral genome integration into host DNA
CR916_RS02685	COG3299	homolog of phage Mu protein gp47
CR916_RS02830	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS02890	COG3121	Chaperone
CR916_RS02895	COG3188	usher protein
CR916_RS02900	COG3539	Fimbrial protein
CR916_RS02905	COG3539	Fimbrial protein
CR916_RS02910	COG3539	Fimbrial protein
CR916_RS02915	COG2610	gluconate transmembrane transporter activity
CR916_RS02930	COG0246	Mannitol dehydrogenase
CR916_RS02940	COG2186	Transcriptional regulator
CR916_RS02960	COG0583	DNA-binding transcription factor activity
CR916_RS02965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CR916_RS02970	COG0700	Nucleoside recognition
CR916_RS02975	COG3366	ferrous iron transmembrane transporter activity
CR916_RS02985	COG0477	Major facilitator Superfamily
CR916_RS03000	COG1924	4 iron, 4 sulfur cluster binding
CR916_RS03005	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CR916_RS03010	COG2733	membrane
CR916_RS03015	COG2814	Major facilitator Superfamily
CR916_RS03035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CR916_RS03040	COG5457	Domain of unknown function (DUF1127)
CR916_RS03060	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CR916_RS03065	COG0732	type I restriction modification DNA specificity domain
CR916_RS03070	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CR916_RS03075	COG1715	Restriction endonuclease
CR916_RS03090	COG0523	cobalamin synthesis protein
CR916_RS03095	COG2879	small protein
CR916_RS03100	COG1966	Carbon starvation protein
CR916_RS03110	COG0840	transmembrane signaling receptor activity
CR916_RS03115	COG2271	Major facilitator Superfamily
CR916_RS03120	COG1802	Transcriptional regulator
CR916_RS03125	COG1063	alcohol dehydrogenase
CR916_RS03140	COG1484	DNA-dependent DNA replication
CR916_RS03155	COG2966	Psort location CytoplasmicMembrane, score
CR916_RS03165	COG2197	response regulator
CR916_RS03170	COG2197	response regulator
CR916_RS03175	COG4114	ferric iron reductase
CR916_RS03205	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CR916_RS03210	COG0456	acetyltransferase
CR916_RS03215	COG1011	Hydrolase
CR916_RS03290	COG3646	Phage regulatory protein
CR916_RS03420	COG3772	lysozyme
CR916_RS03580	COG2823	Periplasmic or secreted lipoprotein
CR916_RS03590	COG4667	esterase of the alpha-beta hydrolase superfamily
CR916_RS03595	COG0084	hydrolase, TatD family'
CR916_RS03605	COG1328	CTP reductase activity
CR916_RS03630	COG3550	peptidyl-serine autophosphorylation
CR916_RS03640	COG3726	membrane protein affecting hemolysin expression
CR916_RS03645	COG0560	Phosphoserine phosphatase
CR916_RS03650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CR916_RS03655	COG1056	cytidyltransferase-related domain
CR916_RS03655	COG3172	ATPase kinase involved in NAD metabolism
CR916_RS03660	COG0488	(ABC) transporter
CR916_RS03670	COG0741	lytic transglycosylase activity
CR916_RS03690	COG3708	Transcriptional regulator
CR916_RS03690	COG2207	Transcriptional regulator
CR916_RS03695	COG3045	CreA protein
CR916_RS03700	COG0745	RESPONSE REGULATOR receiver
CR916_RS03705	COG2205	protein histidine kinase activity
CR916_RS03710	COG4452	Inner membrane protein CreD
CR916_RS03715	COG0745	RESPONSE REGULATOR receiver
CR916_RS03725	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CR916_RS03735	COG0460	homoserine dehydrogenase
CR916_RS03735	COG0527	aspartate kinase activity
CR916_RS03745	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CR916_RS03760	COG1115	amino acid carrier protein
CR916_RS03770	COG0521	Mo-molybdopterin cofactor biosynthetic process
CR916_RS03775	COG1584	GPR1 FUN34 yaaH family protein
CR916_RS03815	COG0583	DNA-binding transcription factor activity
CR916_RS03850	COG0196	riboflavin kinase activity
CR916_RS03865	COG1047	Peptidyl-prolyl cis-trans
CR916_RS03890	COG0505	Belongs to the CarA family
CR916_RS03895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CR916_RS03950	COG0644	oxidoreductase
CR916_RS03955	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CR916_RS03960	COG2271	Major facilitator Superfamily
CR916_RS03980	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CR916_RS04005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CR916_RS04010	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CR916_RS04015	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CR916_RS04020	COG0564	pseudouridine synthase activity
CR916_RS04030	COG0417	DNA replication proofreading
CR916_RS04035	COG0235	Class ii aldolase
CR916_RS04055	COG4977	sequence-specific DNA binding
CR916_RS04060	COG0586	Pfam SNARE associated Golgi protein
CR916_RS04070	COG1178	ABC-type Fe3 transport system permease component
CR916_RS04075	COG4143	(ABC) transporter
CR916_RS04105	COG0473	3-isopropylmalate dehydrogenase activity
CR916_RS04125	COG0028	Belongs to the TPP enzyme family
CR916_RS04130	COG0440	acetolactate synthase activity
CR916_RS04140	COG1609	Transcriptional regulator
CR916_RS04160	COG3116	cell division
CR916_RS04165	COG0768	penicillin binding
CR916_RS04170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CR916_RS04175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CR916_RS04190	COG0772	Belongs to the SEDS family
CR916_RS04205	COG1181	Belongs to the D-alanine--D-alanine ligase family
CR916_RS04210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CR916_RS04215	COG0849	cell division
CR916_RS04220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CR916_RS04245	COG0494	nUDIX hydrolase
CR916_RS04260	COG0237	dephospho-CoA kinase activity
CR916_RS04275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CR916_RS04280	COG4969	Belongs to the N-Me-Phe pilin family
CR916_RS04290	COG0157	Belongs to the NadC ModD family
CR916_RS04295	COG3023	N-Acetylmuramoyl-L-alanine amidase
CR916_RS04300	COG3725	Membrane protein required for beta-lactamase induction
CR916_RS04305	COG1113	amino acid transport
CR916_RS04310	COG2186	Transcriptional regulator
CR916_RS04320	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CR916_RS04325	COG0508	dehydrogenase complex catalyzes the overall conversion of
CR916_RS04330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CR916_RS04335	COG3064	Membrane
CR916_RS04345	COG1049	propionate catabolic process, 2-methylcitrate cycle
CR916_RS04370	COG2132	Multicopper oxidase
CR916_RS04375	COG4993	Dehydrogenase
CR916_RS04380	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CR916_RS04385	COG0288	reversible hydration of carbon dioxide
CR916_RS04390	COG1131	(ABC) transporter
CR916_RS04395	COG0842	Transport permease protein
CR916_RS04400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS04405	COG0726	polysaccharide deacetylase
CR916_RS04420	COG5464	transposase or invertase
CR916_RS04435	COG3539	Fimbrial protein
CR916_RS04440	COG3539	Fimbrial protein
CR916_RS04445	COG3539	Fimbrial protein
CR916_RS04450	COG3539	Fimbrial protein
CR916_RS04455	COG3188	usher protein
CR916_RS04460	COG3121	Chaperone
CR916_RS04465	COG3539	Fimbrial protein
CR916_RS04470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CR916_RS04475	COG0617	tRNA 3'-terminal CCA addition
CR916_RS04485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CR916_RS04495	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CR916_RS04500	COG1643	Atp-dependent helicase
CR916_RS04510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR916_RS04515	COG4774	siderophore transport
CR916_RS04520	COG1120	ATPase activity
CR916_RS04525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CR916_RS04530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CR916_RS04550	COG2860	membrane
CR916_RS04555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CR916_RS04575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CR916_RS04580	COG3835	regulator
CR916_RS04600	COG0024	Methionine aminopeptidase
CR916_RS04635	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CR916_RS04640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CR916_RS04645	COG0575	Belongs to the CDS family
CR916_RS04650	COG0750	zinc metalloprotease
CR916_RS04660	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CR916_RS04665	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CR916_RS04690	COG0587	DNA-directed DNA polymerase activity
CR916_RS04700	COG1982	Orn Lys Arg decarboxylase major
CR916_RS04705	COG0346	lactoylglutathione lyase activity
CR916_RS04715	COG4568	rho-dependent transcription termination
CR916_RS04730	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CR916_RS04735	COG3015	lipoprotein NlpE involved in copper resistance
CR916_RS04750	COG1720	tRNA m6t6A37 methyltransferase activity
CR916_RS04760	COG1464	Belongs to the NlpA lipoprotein family
CR916_RS04765	COG2011	ABC-type metal ion transport system permease component
CR916_RS04770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CR916_RS04775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CR916_RS04820	COG2226	methyltransferase
CR916_RS04825	COG1388	LysM domain
CR916_RS04825	COG0741	lytic transglycosylase activity
CR916_RS04835	COG2226	methyltransferase
CR916_RS04845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CR916_RS04870	COG4104	PAAR repeat-containing protein
CR916_RS04875	COG3157	Type VI secretion system effector, Hcp
CR916_RS04985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CR916_RS04995	COG1960	acyl-CoA dehydrogenase activity
CR916_RS05005	COG0121	glutamine amidotransferase
CR916_RS05010	COG3034	peptidoglycan biosynthetic process
CR916_RS05015	COG3041	Addiction module toxin RelE StbE family
CR916_RS05020	COG3077	Addiction module antitoxin, RelB DinJ family
CR916_RS05065	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CR916_RS05070	COG2195	Cleaves the N-terminal amino acid of tripeptides
CR916_RS05115	COG0582	viral genome integration into host DNA
CR916_RS05200	COG0667	Aldo Keto reductase
CR916_RS05205	COG0656	L-ascorbic acid biosynthetic process
CR916_RS05210	COG1388	LysM domain
CR916_RS05215	COG3708	Transcriptional regulator
CR916_RS05215	COG2207	Transcriptional regulator
CR916_RS05235	COG3059	membrane
CR916_RS05245	COG2207	Transcriptional regulator
CR916_RS05250	COG0247	lactate metabolic process
CR916_RS05255	COG1139	Iron-sulfur cluster binding protein
CR916_RS05260	COG1556	Lactate utilization protein
CR916_RS05285	COG1280	lysine exporter protein (LysE YggA)
CR916_RS05295	COG3829	transcription factor binding
CR916_RS05300	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CR916_RS05305	COG0372	Belongs to the citrate synthase family
CR916_RS05310	COG2079	MmgE PrpD family protein
CR916_RS05315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CR916_RS05320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CR916_RS05325	COG0402	S-adenosylhomocysteine deaminase activity
CR916_RS05330	COG0583	DNA-binding transcription factor activity
CR916_RS05335	COG0288	reversible hydration of carbon dioxide
CR916_RS05345	COG2807	transmembrane transport
CR916_RS05350	COG0110	maltose O-acetyltransferase activity
CR916_RS05355	COG2223	nitrite transmembrane transporter activity
CR916_RS05370	COG1609	Transcriptional regulator
CR916_RS05375	COG1414	Transcriptional regulator
CR916_RS05410	COG2814	Major facilitator Superfamily
CR916_RS05415	COG3122	Protein conserved in bacteria
CR916_RS05455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CR916_RS05470	COG4521	taurine ABC transporter
CR916_RS05480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CR916_RS05485	COG2175	clavaminate synthase activity
CR916_RS05490	COG0113	porphobilinogen synthase activity
CR916_RS05500	COG3468	outer membrane autotransporter barrel domain protein
CR916_RS05505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CR916_RS05510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CR916_RS05520	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CR916_RS05545	COG1181	Belongs to the D-alanine--D-alanine ligase family
CR916_RS05560	COG1785	Belongs to the alkaline phosphatase family
CR916_RS05570	COG3706	GGDEF domain
CR916_RS05575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CR916_RS05600	COG4126	flavin adenine dinucleotide binding
CR916_RS05625	COG1940	carbohydrate kinase activity
CR916_RS05630	COG2814	Major facilitator Superfamily
CR916_RS05635	COG0419	ATPase involved in DNA repair
CR916_RS05640	COG0420	3'-5' exonuclease activity
CR916_RS05645	COG0745	RESPONSE REGULATOR receiver
CR916_RS05650	COG5002	protein histidine kinase activity
CR916_RS05655	COG1114	Component of the transport system for branched-chain amino acids
CR916_RS05660	COG1113	amino acid transport
CR916_RS05665	COG0366	Alpha amylase catalytic
CR916_RS05685	COG1862	Preprotein translocase
CR916_RS05690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CR916_RS05695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CR916_RS05700	COG1403	HNH endonuclease
CR916_RS05705	COG3248	Nucleoside-binding outer membrane protein
CR916_RS05710	COG4238	major outer membrane lipoprotein
CR916_RS05720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CR916_RS05720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CR916_RS05735	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CR916_RS05740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CR916_RS05745	COG0667	Aldo Keto reductase
CR916_RS05755	COG0142	geranyltranstransferase activity
CR916_RS05770	COG0693	protein deglycase activity
CR916_RS05775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CR916_RS05785	COG2814	Major facilitator Superfamily
CR916_RS05810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CR916_RS05815	COG1845	cytochrome c oxidase, subunit III
CR916_RS05820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CR916_RS05825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CR916_RS05830	COG2223	nitrite transmembrane transporter activity
CR916_RS05835	COG3056	Lipoprotein
CR916_RS05840	COG0271	Belongs to the BolA IbaG family
CR916_RS05865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CR916_RS05870	COG0776	regulation of translation
CR916_RS05875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CR916_RS05880	COG1555	photosystem II stabilization
CR916_RS05885	COG0824	Thioesterase
CR916_RS05905	COG1522	sequence-specific DNA binding
CR916_RS05910	COG1132	(ABC) transporter
CR916_RS05915	COG1132	(ABC) transporter
CR916_RS05920	COG0347	Belongs to the P(II) protein family
CR916_RS05925	COG0004	ammonium transporteR
CR916_RS05930	COG1946	Acyl-CoA thioesterase
CR916_RS05935	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CR916_RS05940	COG3695	enzyme binding
CR916_RS05950	COG5507	3-demethylubiquinone-9 3-methyltransferase
CR916_RS05955	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CR916_RS05965	COG0110	maltose O-acetyltransferase activity
CR916_RS05980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CR916_RS05985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CR916_RS05990	COG1309	transcriptional regulator
CR916_RS06000	COG3264	Mechanosensitive ion channel
CR916_RS06000	COG1196	nuclear chromosome segregation
CR916_RS06010	COG3923	Primosomal replication protein n
CR916_RS06015	COG2832	Protein of unknown function (DUF454)
CR916_RS06030	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CR916_RS06070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CR916_RS06075	COG4651	solute:proton antiporter activity
CR916_RS06075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CR916_RS06080	COG2223	nitrite transmembrane transporter activity
CR916_RS06090	COG0737	Belongs to the 5'-nucleotidase family
CR916_RS06095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CR916_RS06105	COG3735	TraB family
CR916_RS06115	COG3093	addiction module antidote protein HigA
CR916_RS06120	COG2217	Heavy metal translocating P-type atpase
CR916_RS06130	COG0531	amino acid
CR916_RS06135	COG0789	Transcriptional regulator
CR916_RS06140	COG1585	Membrane protein implicated in regulation of membrane protease activity
CR916_RS06145	COG0330	HflC and HflK could
CR916_RS06150	COG4619	ABC transporter
CR916_RS06155	COG0390	transport system, permease component
CR916_RS06160	COG3118	belongs to the thioredoxin family
CR916_RS06165	COG0300	oxidoreductase activity
CR916_RS06170	COG2755	lipolytic protein G-D-S-L family
CR916_RS06175	COG4181	ATPase activity
CR916_RS06180	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CR916_RS06230	COG0583	DNA-binding transcription factor activity
CR916_RS06240	COG1414	Transcriptional regulator
CR916_RS06245	COG3960	tartronate-semialdehyde synthase activity
CR916_RS06250	COG3622	Belongs to the hyi family
CR916_RS06255	COG2084	Dehydrogenase
CR916_RS06270	COG2233	PERMEase
CR916_RS06275	COG1929	Belongs to the glycerate kinase type-1 family
CR916_RS06285	COG3257	ureidoglycine aminohydrolase activity
CR916_RS06295	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CR916_RS06300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CR916_RS06305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CR916_RS06315	COG0549	Belongs to the carbamate kinase family
CR916_RS06320	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CR916_RS06325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CR916_RS06340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CR916_RS06350	COG1988	membrane-bound metal-dependent
CR916_RS06355	COG2501	S4 domain
CR916_RS06365	COG3539	Fimbrial protein
CR916_RS06385	COG3539	Fimbrial protein
CR916_RS06390	COG2197	response regulator
CR916_RS06405	COG2207	Transcriptional regulator
CR916_RS06425	COG5002	protein histidine kinase activity
CR916_RS06440	COG1538	Outer membrane efflux protein
CR916_RS06445	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CR916_RS06450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CR916_RS06455	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CR916_RS06460	COG1113	amino acid transport
CR916_RS06465	COG0668	transmembrane transport
CR916_RS06470	COG0778	Nitroreductase
CR916_RS06475	COG2315	Protein conserved in bacteria
CR916_RS06510	COG2977	Belongs to the P-Pant transferase superfamily
CR916_RS06515	COG4771	TonB-dependent receptor
CR916_RS06520	COG2382	esterase
CR916_RS06525	COG3251	PFAM MbtH domain protein
CR916_RS06530	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CR916_RS06530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CR916_RS06545	COG1120	ATPase activity
CR916_RS06550	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CR916_RS06555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CR916_RS06565	COG4592	Periplasmic binding protein
CR916_RS06575	COG1169	isochorismate synthase
CR916_RS06580	COG1021	2,3-dihydroxybenzoate-AMP ligase
CR916_RS06585	COG3433	isochorismatase activity
CR916_RS06585	COG1535	isochorismatase
CR916_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS06595	COG2050	protein possibly involved in aromatic compounds catabolism
CR916_RS06600	COG1966	Carbon starvation protein
CR916_RS06605	COG2879	small protein
CR916_RS06610	COG0371	Dehydrogenase
CR916_RS06620	COG1475	DNA binding
CR916_RS06625	COG3969	phosphoadenosine phosphosulfate
CR916_RS06630	COG0583	DNA-binding transcription factor activity
CR916_RS06635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CR916_RS06640	COG0450	alkyl hydroperoxide reductase
CR916_RS06645	COG3634	alkyl hydroperoxide reductase activity
CR916_RS06650	COG0589	response to stress
CR916_RS06655	COG1063	alcohol dehydrogenase
CR916_RS06665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CR916_RS06675	COG3719	Belongs to the RNase T2 family
CR916_RS06680	COG0471	metal ion transport
CR916_RS06695	COG3051	citrate lyase alpha subunit
CR916_RS06700	COG2301	Belongs to the HpcH HpaI aldolase family
CR916_RS06710	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CR916_RS06715	COG3290	protein histidine kinase activity
CR916_RS06720	COG4565	transcriptional regulatory protein
CR916_RS06725	COG3069	C4-dicarboxylate transmembrane transporter activity
CR916_RS06750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CR916_RS06755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CR916_RS06770	COG0583	DNA-binding transcription factor activity
CR916_RS06790	COG1686	Belongs to the peptidase S11 family
CR916_RS06795	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CR916_RS06800	COG0772	Belongs to the SEDS family
CR916_RS06805	COG0768	penicillin binding
CR916_RS06815	COG0799	negative regulation of ribosome biogenesis
CR916_RS06820	COG0406	alpha-ribazole phosphatase activity
CR916_RS06830	COG1466	dna polymerase III delta subunit
CR916_RS06845	COG2888	peptidyl-tyrosine sulfation
CR916_RS06860	COG2214	Heat shock protein DnaJ domain protein
CR916_RS06865	COG2214	Heat shock protein DnaJ domain protein
CR916_RS06875	COG0443	Heat shock 70 kDa protein
CR916_RS06885	COG1126	abc transporter atp-binding protein
CR916_RS06890	COG0765	amino acid transport
CR916_RS06895	COG0765	amino acid transport
CR916_RS06900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR916_RS06910	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CR916_RS06915	COG4535	Mg2 and Co2 transporter CorC
CR916_RS06925	COG1702	phosphate starvation-inducible protein PhoH
CR916_RS06935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CR916_RS06980	COG0367	asparagine synthase
CR916_RS06990	COG0647	UMP catabolic process
CR916_RS06995	COG1940	carbohydrate kinase activity
CR916_RS06995	COG1846	Transcriptional regulator
CR916_RS07000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CR916_RS07010	COG2190	(PTS) system
CR916_RS07010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS07010	COG1263	PTS System
CR916_RS07035	COG0735	belongs to the Fur family
CR916_RS07045	COG0716	FMN binding
CR916_RS07055	COG0596	Alpha beta hydrolase
CR916_RS07060	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CR916_RS07065	COG0033	Phosphoglucomutase
CR916_RS07070	COG0531	amino acid
CR916_RS07075	COG1982	Orn Lys Arg decarboxylase major
CR916_RS07085	COG0745	RESPONSE REGULATOR receiver
CR916_RS07090	COG2205	protein histidine kinase activity
CR916_RS07145	COG3272	Protein of unknown function (DUF1722)
CR916_RS07150	COG0415	Belongs to the DNA photolyase family
CR916_RS07160	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CR916_RS07165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CR916_RS07170	COG1984	allophanate hydrolase subunit 2
CR916_RS07185	COG3180	Ammonia monooxygenase
CR916_RS07190	COG3539	Fimbrial protein
CR916_RS07195	COG3121	Chaperone
CR916_RS07200	COG3188	usher protein
CR916_RS07210	COG0372	Belongs to the citrate synthase family
CR916_RS07225	COG2009	succinate dehydrogenase
CR916_RS07230	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CR916_RS07235	COG1053	succinate dehydrogenase
CR916_RS07240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CR916_RS07245	COG0567	Dehydrogenase, E1 component
CR916_RS07250	COG0508	dehydrogenase complex catalyzes the overall conversion of
CR916_RS07260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CR916_RS07265	COG2188	Transcriptional regulator
CR916_RS07270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS07270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS07270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS07285	COG1271	oxidase subunit
CR916_RS07290	COG1294	oxidase, subunit
CR916_RS07295	COG4890	Cyd operon protein YbgT
CR916_RS07300	COG3790	cyd operon protein YbgE
CR916_RS07305	COG0824	Thioesterase
CR916_RS07310	COG0811	peptide transport
CR916_RS07315	COG0848	biopolymer transport protein
CR916_RS07320	COG3064	Membrane
CR916_RS07330	COG2885	chlorophyll binding
CR916_RS07335	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CR916_RS07370	COG3201	nicotinamide mononucleotide transporter
CR916_RS07375	COG1230	cation diffusion facilitator family transporter
CR916_RS07390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CR916_RS07400	COG2017	converts alpha-aldose to the beta-anomer
CR916_RS07410	COG1085	galactose-1-phosphate uridylyltransferase
CR916_RS07415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CR916_RS07420	COG1119	ATPase activity
CR916_RS07425	COG3585	molybdate ion transport
CR916_RS07425	COG2005	Transcriptional regulator
CR916_RS07440	COG0725	ABC transporter, periplasmic molybdate-binding protein
CR916_RS07445	COG4149	molybdate abc transporter
CR916_RS07450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CR916_RS07455	COG0561	phosphatase activity
CR916_RS07465	COG0583	DNA-binding transcription factor activity
CR916_RS07480	COG2828	Protein conserved in bacteria
CR916_RS07485	COG0471	metal ion transport
CR916_RS07490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CR916_RS07500	COG4677	pectinesterase activity
CR916_RS07505	COG0582	viral genome integration into host DNA
CR916_RS07535	COG2963	transposase activity
CR916_RS07620	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS07645	COG1881	PFAM PEBP family protein
CR916_RS07650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CR916_RS07665	COG2226	methyltransferase
CR916_RS07670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CR916_RS07680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CR916_RS07690	COG0521	Mo-molybdopterin cofactor biosynthetic process
CR916_RS07700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CR916_RS07705	COG0314	molybdopterin synthase activity
CR916_RS07710	COG0670	Belongs to the BI1 family
CR916_RS07715	COG0670	Belongs to the BI1 family
CR916_RS07720	COG0392	lysyltransferase activity
CR916_RS07725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CR916_RS07730	COG3568	Endonuclease Exonuclease Phosphatase
CR916_RS07740	COG0842	Transport permease protein
CR916_RS07745	COG0842	Transport permease protein
CR916_RS07750	COG1131	(ABC) transporter
CR916_RS07760	COG1309	transcriptional regulator
CR916_RS07765	COG0513	Belongs to the DEAD box helicase family
CR916_RS07770	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CR916_RS07780	COG1199	ATP-dependent helicase activity
CR916_RS07785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CR916_RS07800	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CR916_RS07810	COG4774	siderophore transport
CR916_RS07825	COG0668	transmembrane transport
CR916_RS07830	COG1126	abc transporter atp-binding protein
CR916_RS07835	COG0765	amino acid transport
CR916_RS07840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR916_RS07860	COG5006	permease, DMT superfamily
CR916_RS07865	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CR916_RS07870	COG2194	sulfuric ester hydrolase activity
CR916_RS07880	COG1321	iron dependent repressor
CR916_RS07885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CR916_RS07890	COG1376	ErfK ybiS ycfS ynhG family protein
CR916_RS07895	COG0488	(ABC) transporter
CR916_RS07905	COG0561	phosphatase activity
CR916_RS07910	COG1882	Formate acetyltransferase
CR916_RS07915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CR916_RS07920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CR916_RS07925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CR916_RS07930	COG0303	'Molybdopterin
CR916_RS07935	COG1446	asparaginase
CR916_RS07960	COG2200	EAL domain
CR916_RS07975	COG2199	diguanylate cyclase activity
CR916_RS07995	COG0625	glutathione transferase activity
CR916_RS08000	COG1686	Belongs to the peptidase S11 family
CR916_RS08005	COG1349	DNA-binding transcription factor activity
CR916_RS08010	COG0671	phosphoesterase, PA-phosphatase related
CR916_RS08015	COG2814	Major facilitator Superfamily
CR916_RS08025	COG0561	phosphatase activity
CR916_RS08035	COG3226	Transcriptional regulator
CR916_RS08050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CR916_RS08060	COG0778	Nitroreductase
CR916_RS08080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CR916_RS08085	COG3842	ATPase activity
CR916_RS08090	COG1176	ABC-type spermidine putrescine transport system, permease component I
CR916_RS08095	COG1177	transmembrane transport
CR916_RS08110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR916_RS08115	COG4160	amino acid transport
CR916_RS08120	COG4215	(ABC) transporter
CR916_RS08125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR916_RS08130	COG1126	abc transporter atp-binding protein
CR916_RS08145	COG3023	N-Acetylmuramoyl-L-alanine amidase
CR916_RS08150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CR916_RS08155	COG0702	epimerase
CR916_RS08160	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CR916_RS08165	COG0028	Belongs to the TPP enzyme family
CR916_RS08170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CR916_RS08180	COG2431	L-lysine efflux transmembrane transporter activity
CR916_RS08195	COG3593	DNA synthesis involved in DNA repair
CR916_RS08200	COG2990	Protein conserved in bacteria
CR916_RS08205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CR916_RS08210	COG0577	efflux transmembrane transporter activity
CR916_RS08210	COG1136	(ABC) transporter
CR916_RS08215	COG1278	Cold shock
CR916_RS08225	COG0542	response to heat
CR916_RS08305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CR916_RS08310	COG2194	sulfuric ester hydrolase activity
CR916_RS08325	COG0829	nickel cation binding
CR916_RS08340	COG0804	urea catabolic process
CR916_RS08370	COG0254	rRNA binding
CR916_RS08415	COG3436	PFAM IS66 Orf2 family protein
CR916_RS08420	COG4372	Transposase
CR916_RS08460	COG1358	cellular component organization or biogenesis
CR916_RS08525	COG4771	TonB-dependent receptor
CR916_RS08630	COG2831	hemolysin activation secretion protein
CR916_RS08635	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CR916_RS08640	COG3969	phosphoadenosine phosphosulfate
CR916_RS08645	COG1475	DNA binding
CR916_RS08735	COG3468	outer membrane autotransporter barrel domain protein
CR916_RS08775	COG2003	Belongs to the UPF0758 family
CR916_RS08825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CR916_RS08830	COG4988	ABC transporter
CR916_RS08835	COG0492	ferredoxin-NADP+ reductase activity
CR916_RS08845	COG1522	sequence-specific DNA binding
CR916_RS08860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CR916_RS08870	COG0243	molybdopterin cofactor binding
CR916_RS08875	COG0437	4 iron, 4 sulfur cluster binding
CR916_RS08880	COG3302	dmso reductase anchor subunit
CR916_RS08885	COG1335	isochorismatase
CR916_RS08900	COG0583	DNA-binding transcription factor activity
CR916_RS08905	COG2249	NAD(P)H dehydrogenase (quinone) activity
CR916_RS08910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CR916_RS08915	COG1882	Formate acetyltransferase
CR916_RS08920	COG2116	formate transmembrane transporter activity
CR916_RS08925	COG1944	ATP diphosphatase activity
CR916_RS08930	COG2323	membrane
CR916_RS08945	COG0501	Belongs to the peptidase M48B family
CR916_RS08955	COG0539	negative regulation of cytoplasmic translation
CR916_RS08965	COG2333	competence protein COMEC
CR916_RS08965	COG0658	competence protein
CR916_RS08970	COG1132	(ABC) transporter
CR916_RS08980	COG3214	Protein conserved in bacteria
CR916_RS08995	COG3173	Aminoglycoside phosphotransferase
CR916_RS09000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CR916_RS09005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CR916_RS09015	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CR916_RS09025	COG2989	Protein conserved in bacteria
CR916_RS09035	COG3108	Peptidase M15
CR916_RS09040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CR916_RS09045	COG1448	Aminotransferase
CR916_RS09065	COG0308	aminopeptidase N
CR916_RS09075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CR916_RS09085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CR916_RS09090	COG0431	NADPH-dependent FMN reductase
CR916_RS09100	COG3539	Fimbrial protein
CR916_RS09105	COG3121	Chaperone
CR916_RS09120	COG3539	Fimbrial protein
CR916_RS09125	COG3539	Fimbrial protein
CR916_RS09145	COG0633	Ferredoxin
CR916_RS09145	COG3217	Mosc domain protein beta barrel domain protein
CR916_RS09155	COG0488	(ABC) transporter
CR916_RS09160	COG2995	paraquat-inducible protein a
CR916_RS09165	COG3008	intermembrane lipid transfer
CR916_RS09165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CR916_RS09170	COG3009	Protein conserved in bacteria
CR916_RS09175	COG3130	regulation of translation
CR916_RS09185	COG1067	ATP-dependent peptidase activity
CR916_RS09195	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CR916_RS09195	COG2885	chlorophyll binding
CR916_RS09210	COG3070	regulator of competence-specific genes
CR916_RS09215	COG1289	transmembrane transporter activity
CR916_RS09220	COG3304	Inner membrane component domain
CR916_RS09225	COG0210	DNA helicase
CR916_RS09240	COG1832	CoA-binding protein
CR916_RS09255	COG1254	Belongs to the acylphosphatase family
CR916_RS09260	COG2920	part of a sulfur-relay system
CR916_RS09265	COG0670	Belongs to the BI1 family
CR916_RS09280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CR916_RS09365	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CR916_RS09370	COG1403	HNH endonuclease
CR916_RS09440	COG3772	lysozyme
CR916_RS09470	COG4220	transposase activity
CR916_RS09515	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CR916_RS09520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CR916_RS09525	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CR916_RS09530	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CR916_RS09535	COG1999	signal sequence binding
CR916_RS09540	COG1773	rubredoxin
CR916_RS09545	COG1271	oxidase subunit
CR916_RS09550	COG1294	oxidase, subunit
CR916_RS09565	COG3206	protein involved in exopolysaccharide biosynthesis
CR916_RS09565	COG0489	protein tyrosine kinase activity
CR916_RS09570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CR916_RS09575	COG1596	polysaccharide export
CR916_RS09580	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CR916_RS09600	COG1278	Cold shock
CR916_RS09605	COG1278	Cold shock
CR916_RS09625	COG0348	domain, Protein
CR916_RS09630	COG2205	protein histidine kinase activity
CR916_RS09630	COG2198	Histidine kinase
CR916_RS09630	COG0784	Response regulator, receiver
CR916_RS09635	COG1879	ABC-type sugar transport system periplasmic component
CR916_RS09640	COG0745	RESPONSE REGULATOR receiver
CR916_RS09645	COG3005	denitrification pathway
CR916_RS09650	COG0243	molybdopterin cofactor binding
CR916_RS09695	COG3729	General stress protein
CR916_RS09700	COG2233	PERMEase
CR916_RS09725	COG1335	isochorismatase
CR916_RS09735	COG1309	transcriptional regulator
CR916_RS09740	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CR916_RS09740	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CR916_RS09740	COG0506	proline dehydrogenase activity
CR916_RS09750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CR916_RS09770	COG2822	iron ion transport
CR916_RS09780	COG1702	phosphate starvation-inducible protein PhoH
CR916_RS09785	COG3658	cytochrome
CR916_RS09825	COG3381	protein complex oligomerization
CR916_RS09835	COG1462	curli production assembly transport component CsgG
CR916_RS09850	COG2197	response regulator
CR916_RS09885	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CR916_RS09890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CR916_RS09915	COG2943	transferase activity, transferring hexosyl groups
CR916_RS09920	COG5645	(Lipo)protein
CR916_RS09940	COG1560	Kdo2-lipid A biosynthetic process
CR916_RS09955	COG3038	cytochrome b561
CR916_RS09995	COG2999	glutathione oxidoreductase activity
CR916_RS10005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CR916_RS10015	COG0673	inositol 2-dehydrogenase activity
CR916_RS10020	COG0728	peptidoglycan biosynthetic process
CR916_RS10025	COG3418	PFAM FlgN family protein
CR916_RS10030	COG2747	anti-sigma28 factor FlgM
CR916_RS10035	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CR916_RS10040	COG1815	bacterial-type flagellum-dependent cell motility
CR916_RS10045	COG1558	bacterial-type flagellum-dependent cell motility
CR916_RS10055	COG1749	Flagellar hook protein flgE
CR916_RS10060	COG4787	bacterial-type flagellum-dependent cell motility
CR916_RS10065	COG4786	Flagellar basal body rod
CR916_RS10080	COG3951	Flagellar rod assembly protein muramidase FlgJ
CR916_RS10080	COG1705	Flagellar rod assembly protein muramidase FlgJ
CR916_RS10085	COG1256	bacterial-type flagellum assembly
CR916_RS10090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CR916_RS10095	COG1530	ribonuclease E activity
CR916_RS10105	COG0564	pseudouridine synthase activity
CR916_RS10110	COG0424	maF-like protein
CR916_RS10115	COG1399	metal-binding, possibly nucleic acid-binding protein
CR916_RS10135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CR916_RS10140	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS10150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CR916_RS10155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CR916_RS10160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CR916_RS10170	COG0470	DNA polymerase III
CR916_RS10175	COG0084	hydrolase, TatD family'
CR916_RS10180	COG1263	PTS System
CR916_RS10180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS10185	COG4773	Receptor
CR916_RS10190	COG0537	adenosine 5'-monophosphoramidase activity
CR916_RS10195	COG5633	Lipoprotein
CR916_RS10200	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CR916_RS10220	COG1252	NADH dehydrogenase
CR916_RS10230	COG3134	Outer membrane lipoprotein
CR916_RS10235	COG1309	transcriptional regulator
CR916_RS10245	COG1376	ErfK ybiS ycfS ynhG family protein
CR916_RS10245	COG1388	LysM domain
CR916_RS10250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CR916_RS10260	COG4591	ABC-type transport system involved in lipoprotein release permease component
CR916_RS10270	COG4591	ABC-type transport system involved in lipoprotein release permease component
CR916_RS10280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CR916_RS10285	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CR916_RS10290	COG1177	transmembrane transport
CR916_RS10305	COG0582	viral genome integration into host DNA
CR916_RS10315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CR916_RS10345	COG4197	protein conserved in bacteria, prophage-related
CR916_RS10360	COG1484	DNA-dependent DNA replication
CR916_RS10365	COG1846	Transcriptional regulator
CR916_RS10400	COG3111	PFAM Bacterial OB fold (BOF) protein
CR916_RS10415	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CR916_RS10420	COG0484	heat shock protein binding
CR916_RS10465	COG3772	lysozyme
CR916_RS10595	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS10625	COG3328	transposase activity
CR916_RS10660	COG0582	viral genome integration into host DNA
CR916_RS10670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CR916_RS10710	COG1846	Transcriptional regulator
CR916_RS10715	COG1484	DNA-dependent DNA replication
CR916_RS10720	COG1846	Transcriptional regulator
CR916_RS10770	COG1403	HNH endonuclease
CR916_RS10775	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CR916_RS10860	COG3772	lysozyme
CR916_RS11005	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS11065	COG2850	peptidyl-arginine hydroxylation
CR916_RS11070	COG2205	protein histidine kinase activity
CR916_RS11080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CR916_RS11100	COG1187	pseudouridine synthase activity
CR916_RS11105	COG0538	isocitrate dehydrogenase activity
CR916_RS11110	COG0582	viral genome integration into host DNA
CR916_RS11150	COG5562	phage envelope protein
CR916_RS11175	COG4220	transposase activity
CR916_RS11200	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS11205	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CR916_RS11210	COG3546	catalase activity
CR916_RS11215	COG3685	Protein conserved in bacteria
CR916_RS11220	COG3685	Protein conserved in bacteria
CR916_RS11225	COG3729	General stress protein
CR916_RS11235	COG0500	methyltransferase
CR916_RS11250	COG4571	Outer membrane protease
CR916_RS11280	COG0456	acetyltransferase
CR916_RS11285	COG0538	isocitrate dehydrogenase activity
CR916_RS11295	COG5562	phage envelope protein
CR916_RS11300	COG0789	Transcriptional regulator
CR916_RS11305	COG2200	EAL domain
CR916_RS11385	COG2894	cell division
CR916_RS11415	COG0179	Fumarylacetoacetate (FAA) hydrolase
CR916_RS11435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CR916_RS11440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CR916_RS11460	COG2719	SpoVR family
CR916_RS11470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CR916_RS11485	COG1619	proteins homologs of microcin C7 resistance protein MccF
CR916_RS11500	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CR916_RS11520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CR916_RS11520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS11520	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CR916_RS11525	COG1461	Dihydroxyacetone kinase
CR916_RS11530	COG2376	Dihydroxyacetone kinase
CR916_RS11535	COG3284	Transcriptional regulator
CR916_RS11540	COG3468	outer membrane autotransporter barrel domain protein
CR916_RS11550	COG0012	GTP binding
CR916_RS11565	COG0659	secondary active sulfate transmembrane transporter activity
CR916_RS11575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CR916_RS11605	COG2890	protein-(glutamine-N5) methyltransferase activity
CR916_RS11610	COG3094	Invasion gene expression up-regulator, SirB
CR916_RS11615	COG2912	Transglutaminase-like superfamily
CR916_RS11640	COG0387	Pfam Sodium calcium exchanger
CR916_RS11655	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CR916_RS11660	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CR916_RS11670	COG2197	response regulator
CR916_RS11675	COG3850	Histidine kinase
CR916_RS11685	COG2223	nitrite transmembrane transporter activity
CR916_RS11690	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CR916_RS11695	COG1140	nitrate reductase beta subunit
CR916_RS11700	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CR916_RS11705	COG2181	nitrate reductase activity
CR916_RS11720	COG0788	formyltetrahydrofolate deformylase activity
CR916_RS11730	COG1752	Esterase of the alpha-beta hydrolase superfamily
CR916_RS11735	COG0745	RESPONSE REGULATOR receiver
CR916_RS11740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CR916_RS11750	COG1435	thymidine kinase activity
CR916_RS11755	COG1012	belongs to the aldehyde dehydrogenase family
CR916_RS11755	COG1454	alcohol dehydrogenase
CR916_RS11760	COG2095	MarC family integral membrane protein
CR916_RS11770	COG4166	transmembrane transport
CR916_RS11775	COG0601	transmembrane transport
CR916_RS11780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CR916_RS11785	COG0444	Belongs to the ABC transporter superfamily
CR916_RS11790	COG4608	Belongs to the ABC transporter superfamily
CR916_RS11810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CR916_RS11815	COG2350	Protein conserved in bacteria
CR916_RS11820	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CR916_RS11825	COG1607	acyl-coa hydrolase
CR916_RS11840	COG3047	cAMP biosynthetic process
CR916_RS11845	COG3685	Protein conserved in bacteria
CR916_RS11850	COG3685	Protein conserved in bacteria
CR916_RS11855	COG3729	General stress protein
CR916_RS11870	COG0135	phosphoribosylanthranilate isomerase activity
CR916_RS11870	COG0134	indole-3-glycerol-phosphate synthase activity
CR916_RS11875	COG0512	Glutamine amidotransferase of anthranilate synthase
CR916_RS11875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CR916_RS11880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CR916_RS11890	COG0613	PHP domain protein
CR916_RS11895	COG0009	L-threonylcarbamoyladenylate synthase
CR916_RS11900	COG1187	pseudouridine synthase activity
CR916_RS11905	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CR916_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS11915	COG0616	signal peptide processing
CR916_RS11930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CR916_RS11940	COG0583	DNA-binding transcription factor activity
CR916_RS11960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CR916_RS11970	COG0671	phosphoesterase, PA-phosphatase related
CR916_RS11975	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CR916_RS11980	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CR916_RS11990	COG0023	Translation Initiation Factor
CR916_RS12000	COG1349	DNA-binding transcription factor activity
CR916_RS12025	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CR916_RS12025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CR916_RS12030	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CR916_RS12040	COG2852	Protein conserved in bacteria
CR916_RS12045	COG4172	Belongs to the ABC transporter superfamily
CR916_RS12050	COG4172	Belongs to the ABC transporter superfamily
CR916_RS12055	COG4171	peptide transport system, permease
CR916_RS12060	COG4168	peptide transport system, permease
CR916_RS12065	COG4166	transmembrane transport
CR916_RS12085	COG0174	glutamine synthetase
CR916_RS12090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CR916_RS12095	COG1917	Cupin 2, conserved barrel domain protein
CR916_RS12095	COG1396	sequence-specific DNA binding
CR916_RS12105	COG1012	belongs to the aldehyde dehydrogenase family
CR916_RS12110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CR916_RS12115	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CR916_RS12120	COG1842	Phage shock protein A
CR916_RS12130	COG1983	PspC domain protein
CR916_RS12140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CR916_RS12145	COG0366	Alpha amylase catalytic
CR916_RS12150	COG1653	transport
CR916_RS12155	COG1175	transmembrane transport
CR916_RS12160	COG0395	ABC-type sugar transport system, permease component
CR916_RS12165	COG1063	alcohol dehydrogenase
CR916_RS12170	COG1082	Xylose isomerase domain protein TIM barrel
CR916_RS12175	COG0673	inositol 2-dehydrogenase activity
CR916_RS12180	COG1554	hydrolase, family 65, central catalytic
CR916_RS12185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CR916_RS12190	COG3842	ATPase activity
CR916_RS12200	COG1609	Transcriptional regulator
CR916_RS12205	COG3106	COG3106 Predicted ATPase
CR916_RS12215	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CR916_RS12225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CR916_RS12230	COG4948	Mandelate Racemase Muconate Lactonizing
CR916_RS12235	COG2866	Carboxypeptidase
CR916_RS12240	COG0702	epimerase
CR916_RS12245	COG1073	alpha beta
CR916_RS12260	COG4166	transmembrane transport
CR916_RS12265	COG0668	transmembrane transport
CR916_RS12270	COG3182	Iron-regulated membrane protein
CR916_RS12275	COG0589	response to stress
CR916_RS12280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CR916_RS12285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CR916_RS12290	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CR916_RS12300	COG2207	Transcriptional regulator
CR916_RS12315	COG2840	Smr protein MutS2
CR916_RS12320	COG3706	GGDEF domain
CR916_RS12335	COG0513	Belongs to the DEAD box helicase family
CR916_RS12345	COG0582	viral genome integration into host DNA
CR916_RS12365	COG3723	Recombinational DNA repair protein, rece pathway
CR916_RS12370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CR916_RS12385	COG3646	Phage regulatory protein
CR916_RS12410	COG3756	Protein conserved in bacteria
CR916_RS12415	COG1484	DNA-dependent DNA replication
CR916_RS12420	COG1846	Transcriptional regulator
CR916_RS12495	COG3772	lysozyme
CR916_RS12535	COG0740	serine-type endopeptidase activity
CR916_RS12610	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS12635	COG0589	response to stress
CR916_RS12650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CR916_RS12650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CR916_RS12650	COG0674	pyruvate-flavodoxin oxidoreductase activity
CR916_RS12650	COG1013	pyruvate-flavodoxin oxidoreductase activity
CR916_RS12655	COG3042	response to heat
CR916_RS12660	COG3187	Heat shock protein
CR916_RS12665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CR916_RS12670	COG2911	Protein conserved in bacteria
CR916_RS12680	COG3784	Protein of unknown function (DUF1318)
CR916_RS12690	COG1012	belongs to the aldehyde dehydrogenase family
CR916_RS12695	COG3733	amine oxidase
CR916_RS12700	COG2030	dehydratase
CR916_RS12700	COG1012	belongs to the aldehyde dehydrogenase family
CR916_RS12705	COG3396	Phenylacetate-CoA oxygenase
CR916_RS12710	COG3460	Phenylacetate-CoA oxygenase
CR916_RS12715	COG3396	Phenylacetate-CoA oxygenase
CR916_RS12720	COG2151	metal-sulfur cluster biosynthetic enzyme
CR916_RS12725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CR916_RS12730	COG1024	Enoyl-CoA hydratase
CR916_RS12735	COG1024	Enoyl-CoA hydratase
CR916_RS12745	COG2050	protein possibly involved in aromatic compounds catabolism
CR916_RS12750	COG0183	Belongs to the thiolase family
CR916_RS12760	COG3327	negative regulation of DNA-templated transcription, initiation
CR916_RS12765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CR916_RS12770	COG0667	Aldo Keto reductase
CR916_RS12780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CR916_RS12785	COG4589	Belongs to the CDS family
CR916_RS12790	COG2267	carboxylic ester hydrolase activity
CR916_RS12795	COG2453	phosphatase
CR916_RS12795	COG0671	phosphoesterase, PA-phosphatase related
CR916_RS12805	COG1643	Atp-dependent helicase
CR916_RS12810	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CR916_RS12815	COG1012	belongs to the aldehyde dehydrogenase family
CR916_RS12820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CR916_RS12825	COG3038	cytochrome b561
CR916_RS12895	COG3772	lysozyme
CR916_RS13015	COG2032	superoxide dismutase activity
CR916_RS13030	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS13070	COG1802	Transcriptional regulator
CR916_RS13075	COG4221	oxidoreductase activity
CR916_RS13085	COG0339	signal peptide processing
CR916_RS13090	COG1546	Belongs to the CinA family
CR916_RS13105	COG1802	Transcriptional regulator
CR916_RS13110	COG4772	TonB-dependent receptor
CR916_RS13125	COG3391	amine dehydrogenase activity
CR916_RS13130	COG1113	amino acid transport
CR916_RS13135	COG0625	glutathione transferase activity
CR916_RS13180	COG3547	Transposase (IS116 IS110 IS902 family)
CR916_RS13185	COG5433	transposase activity
CR916_RS13195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CR916_RS13200	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CR916_RS13205	COG0384	phenazine biosynthesis protein PhzF
CR916_RS13210	COG2181	nitrate reductase activity
CR916_RS13215	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CR916_RS13220	COG1140	nitrate reductase beta subunit
CR916_RS13225	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CR916_RS13230	COG2223	nitrite transmembrane transporter activity
CR916_RS13240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CR916_RS13245	COG0697	spore germination
CR916_RS13250	COG0243	molybdopterin cofactor binding
CR916_RS13250	COG3383	formate dehydrogenase (NAD+) activity
CR916_RS13255	COG3383	formate dehydrogenase (NAD+) activity
CR916_RS13255	COG0243	molybdopterin cofactor binding
CR916_RS13260	COG0437	4 iron, 4 sulfur cluster binding
CR916_RS13265	COG2864	formate dehydrogenase
CR916_RS13270	COG3093	addiction module antidote protein HigA
CR916_RS13275	COG1064	alcohol dehydrogenase
CR916_RS13300	COG1764	response to oxidative stress
CR916_RS13305	COG4608	Belongs to the ABC transporter superfamily
CR916_RS13315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CR916_RS13320	COG0601	transmembrane transport
CR916_RS13325	COG0747	negative chemotaxis
CR916_RS13330	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CR916_RS13335	COG2202	Pas domain
CR916_RS13335	COG2200	EAL domain
CR916_RS13335	COG2199	diguanylate cyclase activity
CR916_RS13345	COG1649	PFAM Uncharacterised BCR, COG1649
CR916_RS13350	COG0531	amino acid
CR916_RS13355	COG0076	glutamate decarboxylase activity
CR916_RS13370	COG0641	radical SAM
CR916_RS13375	COG3119	arylsulfatase activity
CR916_RS13390	COG0243	molybdopterin cofactor binding
CR916_RS13395	COG3539	Fimbrial protein
CR916_RS13400	COG3539	Fimbrial protein
CR916_RS13405	COG3539	Fimbrial protein
CR916_RS13410	COG3188	usher protein
CR916_RS13420	COG3539	Fimbrial protein
CR916_RS13435	COG4977	sequence-specific DNA binding
CR916_RS13445	COG3550	peptidyl-serine autophosphorylation
CR916_RS13450	COG1396	sequence-specific DNA binding
CR916_RS13465	COG3547	Transposase (IS116 IS110 IS902 family)
CR916_RS13470	COG3210	domain, Protein
CR916_RS13470	COG2911	Protein conserved in bacteria
CR916_RS13510	COG3781	membrane
CR916_RS13530	COG2199	diguanylate cyclase activity
CR916_RS13545	COG2066	Belongs to the glutaminase family
CR916_RS13550	COG1012	belongs to the aldehyde dehydrogenase family
CR916_RS13555	COG0583	DNA-binding transcription factor activity
CR916_RS13575	COG1846	Transcriptional regulator
CR916_RS13580	COG4977	sequence-specific DNA binding
CR916_RS13590	COG0697	spore germination
CR916_RS13605	COG3706	GGDEF domain
CR916_RS13610	COG3111	PFAM Bacterial OB fold (BOF) protein
CR916_RS13630	COG1247	-acetyltransferase
CR916_RS13635	COG3238	Protein conserved in bacteria
CR916_RS13675	COG1176	ABC-type spermidine putrescine transport system, permease component I
CR916_RS13680	COG3842	ATPase activity
CR916_RS13685	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CR916_RS13690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CR916_RS13695	COG1598	PFAM Uncharacterised protein family UPF0150
CR916_RS13700	COG1724	mRNA binding
CR916_RS13710	COG0826	peptidase U32
CR916_RS13715	COG1396	sequence-specific DNA binding
CR916_RS13720	COG3135	benzoate transporter
CR916_RS13725	COG0675	Transposase, IS605 OrfB family
CR916_RS13740	COG0500	methyltransferase
CR916_RS13745	COG1275	C4-dicarboxylate transporter malic acid transport protein
CR916_RS13750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CR916_RS13755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CR916_RS13760	COG2841	Protein conserved in bacteria
CR916_RS13780	COG5383	Protein conserved in bacteria
CR916_RS13785	COG0583	DNA-binding transcription factor activity
CR916_RS13790	COG0840	transmembrane signaling receptor activity
CR916_RS13795	COG0840	transmembrane signaling receptor activity
CR916_RS13885	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CR916_RS13890	COG1403	HNH endonuclease
CR916_RS13950	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS14055	COG3772	lysozyme
CR916_RS14095	COG0484	heat shock protein binding
CR916_RS14100	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CR916_RS14105	COG1403	HNH endonuclease
CR916_RS14155	COG1846	Transcriptional regulator
CR916_RS14175	COG1396	sequence-specific DNA binding
CR916_RS14215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CR916_RS14225	COG0582	viral genome integration into host DNA
CR916_RS14300	COG3436	PFAM IS66 Orf2 family protein
CR916_RS14310	COG1063	alcohol dehydrogenase
CR916_RS14315	COG4948	Mandelate Racemase Muconate Lactonizing
CR916_RS14335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CR916_RS14355	COG0243	molybdopterin cofactor binding
CR916_RS14360	COG0437	4 iron, 4 sulfur cluster binding
CR916_RS14365	COG3302	dmso reductase anchor subunit
CR916_RS14370	COG3381	protein complex oligomerization
CR916_RS14380	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CR916_RS14385	COG1940	carbohydrate kinase activity
CR916_RS14390	COG0583	DNA-binding transcription factor activity
CR916_RS14395	COG2814	Major facilitator Superfamily
CR916_RS14415	COG3591	Belongs to the peptidase S1B family
CR916_RS14435	COG0628	permease
CR916_RS14440	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CR916_RS14445	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CR916_RS14460	COG0531	amino acid
CR916_RS14470	COG3136	membrane protein required for alginate biosynthesis
CR916_RS14475	COG0745	RESPONSE REGULATOR receiver
CR916_RS14480	COG2205	protein histidine kinase activity
CR916_RS14490	COG0114	fumarate hydratase activity
CR916_RS14495	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CR916_RS14495	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CR916_RS14500	COG1482	cell wall glycoprotein biosynthetic process
CR916_RS14505	COG5339	Protein conserved in bacteria
CR916_RS14520	COG3250	beta-galactosidase activity
CR916_RS14525	COG1309	transcriptional regulator
CR916_RS14530	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS14535	COG1609	Transcriptional regulator
CR916_RS14540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS14540	COG1263	PTS System
CR916_RS14545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CR916_RS14555	COG0673	inositol 2-dehydrogenase activity
CR916_RS14600	COG4659	FMN binding
CR916_RS14610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CR916_RS14620	COG3104	oligopeptide transport
CR916_RS14625	COG0625	glutathione transferase activity
CR916_RS14630	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CR916_RS14645	COG3895	Periplasmic Protein
CR916_RS14660	COG3133	Outer membrane lipoprotein
CR916_RS14675	COG1566	PFAM secretion protein HlyD family protein
CR916_RS14680	COG1289	transmembrane transporter activity
CR916_RS14685	COG2032	superoxide dismutase activity
CR916_RS14690	COG4989	oxidoreductase activity
CR916_RS14695	COG3313	Fe-S protein
CR916_RS14700	COG1309	transcriptional regulator
CR916_RS14705	COG1902	pentaerythritol trinitrate reductase activity
CR916_RS14710	COG0346	lactoylglutathione lyase activity
CR916_RS14720	COG1201	RNA secondary structure unwinding
CR916_RS14725	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CR916_RS14730	COG0791	NLP P60 protein
CR916_RS14735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CR916_RS14740	COG2814	Major facilitator Superfamily
CR916_RS14760	COG0583	DNA-binding transcription factor activity
CR916_RS14765	COG2814	Major facilitator Superfamily
CR916_RS14770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CR916_RS14775	COG0307	riboflavin synthase, alpha
CR916_RS14785	COG3468	outer membrane autotransporter barrel domain protein
CR916_RS14805	COG4529	Protein conserved in bacteria
CR916_RS14815	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CR916_RS14820	COG0437	4 iron, 4 sulfur cluster binding
CR916_RS14835	COG0437	4 iron, 4 sulfur cluster binding
CR916_RS14845	COG0469	pyruvate kinase activity
CR916_RS14850	COG4238	major outer membrane lipoprotein
CR916_RS14855	COG1376	ErfK ybiS ycfS ynhG family protein
CR916_RS14870	COG0719	Fe-S assembly protein
CR916_RS14875	COG0396	ATPase activity
CR916_RS14880	COG0719	Fe-S assembly protein
CR916_RS14885	COG0316	Belongs to the HesB IscA family
CR916_RS14895	COG2050	protein possibly involved in aromatic compounds catabolism
CR916_RS14900	COG0277	FAD linked oxidase domain protein
CR916_RS14900	COG0247	lactate metabolic process
CR916_RS14905	COG0628	permease
CR916_RS14920	COG0738	Major facilitator superfamily
CR916_RS14925	COG2271	Major facilitator Superfamily
CR916_RS14940	COG4670	ketone body catabolic process
CR916_RS14945	COG1960	acyl-CoA dehydrogenase activity
CR916_RS14960	COG2086	electron transfer activity
CR916_RS14965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CR916_RS14970	COG0644	oxidoreductase
CR916_RS14975	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CR916_RS14980	COG0318	PFAM AMP-dependent synthetase and ligase
CR916_RS14985	COG0574	Belongs to the PEP-utilizing enzyme family
CR916_RS14985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CR916_RS15000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CR916_RS15005	COG4256	Hemin uptake protein
CR916_RS15015	COG2200	EAL domain
CR916_RS15020	COG0791	NLP P60 protein
CR916_RS15030	COG0386	Belongs to the glutathione peroxidase family
CR916_RS15110	COG3137	Salt-induced outer membrane protein
CR916_RS15115	COG1105	Belongs to the carbohydrate kinase PfkB family
CR916_RS15125	COG3001	Fructosamine kinase
CR916_RS15135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CR916_RS15140	COG1988	membrane-bound metal-dependent
CR916_RS15145	COG1823	symporter activity
CR916_RS15160	COG0753	catalase activity
CR916_RS15170	COG1486	melibiose metabolic process
CR916_RS15175	COG1917	Cupin 2, conserved barrel domain protein
CR916_RS15175	COG2169	Transcriptional regulator
CR916_RS15180	COG1447	Phosphotransferase system cellobiose-specific component IIA
CR916_RS15185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR916_RS15190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR916_RS15200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CR916_RS15220	COG3678	ATP-independent chaperone mediated protein folding
CR916_RS15255	COG0708	Exodeoxyribonuclease III
CR916_RS15260	COG0398	Pfam SNARE associated Golgi protein
CR916_RS15270	COG0398	Pfam SNARE associated Golgi protein
CR916_RS15275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CR916_RS15280	COG4134	Bacterial extracellular solute-binding protein
CR916_RS15285	COG4135	transport system, permease component
CR916_RS15290	COG4136	ATPase activity
CR916_RS15295	COG2897	thiosulfate sulfurtransferase activity
CR916_RS15300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CR916_RS15305	COG0494	nUDIX hydrolase
CR916_RS15315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CR916_RS15325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CR916_RS15340	COG0778	Nitroreductase
CR916_RS15350	COG0616	signal peptide processing
CR916_RS15355	COG0252	asparaginase activity
CR916_RS15360	COG1335	isochorismatase
CR916_RS15365	COG2814	Major facilitator Superfamily
CR916_RS15370	COG1349	DNA-binding transcription factor activity
CR916_RS15390	COG1063	alcohol dehydrogenase
CR916_RS15395	COG2271	Major facilitator Superfamily
CR916_RS15400	COG1063	alcohol dehydrogenase
CR916_RS15405	COG3139	Protein of unknown function (DUF1315)
CR916_RS15415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CR916_RS15420	COG0676	glucose-6-phosphate 1-epimerase activity
CR916_RS15425	COG0656	L-ascorbic acid biosynthetic process
CR916_RS15430	COG3713	MltA-interacting MipA family protein
CR916_RS15435	COG2766	serine protein kinase
CR916_RS15445	COG2199	diguanylate cyclase activity
CR916_RS15450	COG2199	diguanylate cyclase activity
CR916_RS15455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CR916_RS15470	COG2207	Transcriptional regulator
CR916_RS15475	COG2807	transmembrane transport
CR916_RS15480	COG3189	MarR family transcriptional regulator
CR916_RS15485	COG3042	response to heat
CR916_RS15490	COG2203	Gaf domain
CR916_RS15490	COG2199	diguanylate cyclase activity
CR916_RS15505	COG2261	transglycosylase associated protein
CR916_RS15515	COG3615	Tellurite resistance protein tehB
CR916_RS15525	COG0583	DNA-binding transcription factor activity
CR916_RS15530	COG0473	3-isopropylmalate dehydrogenase activity
CR916_RS15535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CR916_RS15540	COG4638	Rieske (2fe-2S)
CR916_RS15545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CR916_RS15550	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CR916_RS15555	COG0318	PFAM AMP-dependent synthetase and ligase
CR916_RS15560	COG3065	identical protein binding
CR916_RS15565	COG1214	PFAM Peptidase M22, glycoprotease
CR916_RS15570	COG1199	ATP-dependent helicase activity
CR916_RS15575	COG0251	oxidation-reduction process
CR916_RS15590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CR916_RS15600	COG1760	l-serine dehydratase
CR916_RS15605	COG2200	EAL domain
CR916_RS15610	COG1253	flavin adenine dinucleotide binding
CR916_RS15625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS15625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS15630	COG3715	PTS system
CR916_RS15635	COG3716	PTS system mannose fructose sorbose family IID component
CR916_RS15655	COG2226	methyltransferase
CR916_RS15690	COG1414	Transcriptional regulator
CR916_RS15695	COG2814	Major facilitator Superfamily
CR916_RS15705	COG0793	Belongs to the peptidase S41A family
CR916_RS15715	COG1956	GAF domain-containing protein
CR916_RS15720	COG2995	paraquat-inducible protein a
CR916_RS15725	COG3008	intermembrane lipid transfer
CR916_RS15745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CR916_RS15755	COG1276	copper resistance
CR916_RS15760	COG2372	response to copper ion
CR916_RS15770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CR916_RS15775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CR916_RS15780	COG1770	oligopeptidase
CR916_RS15785	COG2979	Protein of unknown function (DUF533)
CR916_RS15795	COG3141	response to X-ray
CR916_RS15805	COG0800	Aldolase
CR916_RS15810	COG0129	dihydroxy-acid dehydratase activity
CR916_RS15815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CR916_RS15820	COG1737	Transcriptional regulator
CR916_RS15825	COG0469	pyruvate kinase activity
CR916_RS15830	COG1560	Kdo2-lipid A biosynthetic process
CR916_RS15835	COG0739	heme binding
CR916_RS15840	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CR916_RS15850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CR916_RS15880	COG0217	transcriptional regulatory protein
CR916_RS15885	COG0494	nUDIX hydrolase
CR916_RS15895	COG1335	isochorismatase
CR916_RS15900	COG1801	Protein of unknown function DUF72
CR916_RS15905	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CR916_RS15920	COG0243	molybdopterin cofactor binding
CR916_RS15925	COG3005	denitrification pathway
CR916_RS15935	COG3102	Protein conserved in bacteria
CR916_RS15950	COG3755	Protein conserved in bacteria
CR916_RS15960	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CR916_RS15965	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CR916_RS15975	COG0745	RESPONSE REGULATOR receiver
CR916_RS15985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CR916_RS15990	COG0840	transmembrane signaling receptor activity
CR916_RS15995	COG0840	transmembrane signaling receptor activity
CR916_RS16000	COG0835	chemotaxis
CR916_RS16010	COG1360	Flagellar Motor Protein
CR916_RS16015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CR916_RS16030	COG0589	response to stress
CR916_RS16040	COG1877	trehalose-phosphatase activity
CR916_RS16045	COG1172	Belongs to the binding-protein-dependent transport system permease family
CR916_RS16050	COG1129	ABC transporter
CR916_RS16055	COG1879	ABC-type sugar transport system periplasmic component
CR916_RS16065	COG1528	Iron-storage protein
CR916_RS16085	COG1528	Iron-storage protein
CR916_RS16095	COG0814	amino acid
CR916_RS16100	COG3012	SEC-C Motif Domain Protein
CR916_RS16100	COG3318	Belongs to the UPF0149 family
CR916_RS16105	COG4974	Belongs to the 'phage' integrase family
CR916_RS16185	COG4695	Portal protein
CR916_RS16270	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS16275	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CR916_RS16365	COG2197	response regulator
CR916_RS16380	COG1126	abc transporter atp-binding protein
CR916_RS16385	COG0765	amino acid transport
CR916_RS16395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR916_RS16410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CR916_RS16415	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CR916_RS16420	COG1516	flagellar protein fliS
CR916_RS16430	COG0366	Alpha amylase catalytic
CR916_RS16445	COG2391	methyltransferase activity
CR916_RS16450	COG0425	Belongs to the sulfur carrier protein TusA family
CR916_RS16455	COG2135	peptidase activity
CR916_RS16475	COG1766	The M ring may be actively involved in energy transduction
CR916_RS16480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CR916_RS16485	COG1317	bacterial-type flagellum organization
CR916_RS16495	COG3547	Transposase (IS116 IS110 IS902 family)
CR916_RS16505	COG2882	bacterial-type flagellum organization
CR916_RS16510	COG3144	bacterial-type flagellum assembly
CR916_RS16515	COG1580	Controls the rotational direction of flagella during chemotaxis
CR916_RS16520	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CR916_RS16525	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CR916_RS16530	COG3190	flagellar
CR916_RS16535	COG1338	Plays a role in the flagellum-specific transport system
CR916_RS16540	COG1987	bacterial-type flagellum assembly
CR916_RS16545	COG1684	flagellar biosynthetic protein fliR
CR916_RS16550	COG2197	response regulator
CR916_RS16575	COG3706	GGDEF domain
CR916_RS16585	COG5475	Uncharacterized small protein (DUF2158)
CR916_RS16590	COG2354	Protein conserved in bacteria
CR916_RS16595	COG0697	spore germination
CR916_RS16600	COG3727	T/G mismatch-specific endonuclease activity
CR916_RS16605	COG0270	DNA (cytosine-5-)-methyltransferase activity
CR916_RS16610	COG1418	mRNA catabolic process
CR916_RS16620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CR916_RS16635	COG2205	protein histidine kinase activity
CR916_RS16640	COG0745	RESPONSE REGULATOR receiver
CR916_RS16645	COG2351	hydroxyisourate hydrolase activity
CR916_RS16660	COG3443	Belongs to the bacterial solute-binding protein 9 family
CR916_RS16670	COG3038	cytochrome b561
CR916_RS16700	COG3772	lysozyme
CR916_RS16755	COG2842	Transposition protein
CR916_RS16785	COG4396	Host-nuclease inhibitor protein Gam
CR916_RS16840	COG5566	PFAM Mor transcription activator
CR916_RS16875	COG4373	Mu-like prophage FluMu protein gp28
CR916_RS16880	COG4383	Mu-like prophage protein gp29
CR916_RS16885	COG2369	cell adhesion
CR916_RS16890	COG5005	Phage virion morphogenesis
CR916_RS16895	COG4388	Caudovirus prohead serine protease
CR916_RS16900	COG4397	Mu-like prophage major head subunit gpT
CR916_RS16925	COG4386	tail sheath protein
CR916_RS16935	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
CR916_RS16955	COG4384	Bacteriophage Mu Gp45 protein
CR916_RS16995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CR916_RS17050	COG2207	Transcriptional regulator
CR916_RS17065	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CR916_RS17070	COG1403	HNH endonuclease
CR916_RS17080	COG3111	PFAM Bacterial OB fold (BOF) protein
CR916_RS17115	COG1846	Transcriptional regulator
CR916_RS17120	COG1484	DNA-dependent DNA replication
CR916_RS17180	COG0477	Major facilitator Superfamily
CR916_RS17185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CR916_RS17190	COG0217	transcriptional regulatory protein
CR916_RS17210	COG0534	Mate efflux family protein
CR916_RS17220	COG0583	DNA-binding transcription factor activity
CR916_RS17225	COG0583	DNA-binding transcription factor activity
CR916_RS17235	COG1376	ErfK ybiS ycfS ynhG family protein
CR916_RS17250	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CR916_RS17280	COG4917	ethanolamine utilization protein
CR916_RS17290	COG1289	transmembrane transporter activity
CR916_RS17300	COG2826	transposase and inactivated derivatives, IS30 family
CR916_RS17320	COG2925	Exonuclease
CR916_RS17325	COG0425	Belongs to the sulfur carrier protein TusA family
CR916_RS17330	COG2391	methyltransferase activity
CR916_RS17335	COG0531	amino acid
CR916_RS17345	COG0583	DNA-binding transcription factor activity
CR916_RS17350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CR916_RS17360	COG2161	toxin-antitoxin pair type II binding
CR916_RS17380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CR916_RS17390	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CR916_RS17390	COG0131	Imidazoleglycerol-phosphate dehydratase
CR916_RS17395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CR916_RS17425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CR916_RS17430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CR916_RS17445	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CR916_RS17485	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CR916_RS17490	COG1091	dTDP-4-dehydrorhamnose reductase activity
CR916_RS17495	COG1088	dTDP-glucose 4,6-dehydratase activity
CR916_RS17505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CR916_RS17515	COG0438	transferase activity, transferring glycosyl groups
CR916_RS17520	COG2327	Polysaccharide pyruvyl transferase
CR916_RS17525	COG2244	polysaccharide biosynthetic process
CR916_RS17530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CR916_RS17535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CR916_RS17540	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CR916_RS17540	COG0662	Cupin 2, conserved barrel domain protein
CR916_RS17545	COG0297	glycogen (starch) synthase activity
CR916_RS17550	COG1051	belongs to the nudix hydrolase family
CR916_RS17555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CR916_RS17560	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CR916_RS17565	COG0110	maltose O-acetyltransferase activity
CR916_RS17570	COG1216	Glycosyl transferase, family 2
CR916_RS17580	COG0438	transferase activity, transferring glycosyl groups
CR916_RS17585	COG1045	serine acetyltransferase
CR916_RS17590	COG0463	Glycosyl transferase, family 2
CR916_RS17595	COG0489	protein tyrosine kinase activity
CR916_RS17595	COG3206	protein involved in exopolysaccharide biosynthesis
CR916_RS17600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CR916_RS17605	COG1596	polysaccharide export
CR916_RS17610	COG1253	flavin adenine dinucleotide binding
CR916_RS17615	COG2982	Protein involved in outer membrane biogenesis
CR916_RS17625	COG0572	uridine kinase
CR916_RS17635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CR916_RS17640	COG0443	Heat shock 70 kDa protein
CR916_RS17645	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CR916_RS17650	COG3779	Protein conserved in bacteria
CR916_RS17655	COG0631	protein serine/threonine phosphatase activity
CR916_RS17660	COG4245	von Willebrand factor, type A
CR916_RS17700	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CR916_RS17740	COG4220	transposase activity
CR916_RS17775	COG3772	lysozyme
CR916_RS17840	COG0582	viral genome integration into host DNA
CR916_RS17865	COG2205	protein histidine kinase activity
CR916_RS17870	COG0745	RESPONSE REGULATOR receiver
CR916_RS17880	COG3609	addiction module antidote protein, CC2985 family
CR916_RS17890	COG0826	peptidase U32
CR916_RS17915	COG1063	alcohol dehydrogenase
CR916_RS17925	COG3775	system Galactitol-specific IIC component
CR916_RS17930	COG3414	Phosphotransferase system galactitol-specific IIB component
CR916_RS17935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS17950	COG1830	Aldolase
CR916_RS17955	COG2211	Major facilitator Superfamily
CR916_RS17960	COG1397	ADP-ribosylglycohydrolase
CR916_RS17970	COG2188	Transcriptional regulator
CR916_RS17975	COG3757	hydrolase, family 25
CR916_RS17980	COG0351	phosphomethylpyrimidine kinase
CR916_RS17995	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CR916_RS18000	COG5455	response to cobalt ion
CR916_RS18005	COG3539	Fimbrial protein
CR916_RS18025	COG3121	Chaperone
CR916_RS18030	COG3539	Fimbrial protein
CR916_RS18040	COG0489	protein tyrosine kinase activity
CR916_RS18065	COG0714	Associated with various cellular activities
CR916_RS18070	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CR916_RS18075	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CR916_RS18080	COG4715	Zinc finger, swim domain protein
CR916_RS18085	COG4808	Protein conserved in bacteria
CR916_RS18090	COG4807	Protein conserved in bacteria
CR916_RS18095	COG3279	Response regulator of the LytR AlgR family
CR916_RS18100	COG3275	phosphorelay sensor kinase activity
CR916_RS18270	COG3772	lysozyme
CR916_RS18385	COG0515	serine threonine protein kinase
CR916_RS18490	COG0582	viral genome integration into host DNA
CR916_RS18495	COG0789	Transcriptional regulator
CR916_RS18505	COG1174	glycine betaine transport
CR916_RS18510	COG1125	glycine betaine transport
CR916_RS18515	COG1174	glycine betaine transport
CR916_RS18520	COG1732	Glycine betaine
CR916_RS18525	COG1472	Belongs to the glycosyl hydrolase 3 family
CR916_RS18530	COG0277	FAD linked oxidase domain protein
CR916_RS18535	COG1686	Belongs to the peptidase S11 family
CR916_RS18545	COG0586	Pfam SNARE associated Golgi protein
CR916_RS18550	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS18575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CR916_RS18585	COG1346	cytolysis
CR916_RS18595	COG2949	membrane
CR916_RS18605	COG0493	'glutamate synthase
CR916_RS18615	COG4211	Belongs to the binding-protein-dependent transport system permease family
CR916_RS18620	COG1129	ABC transporter
CR916_RS18625	COG1879	ABC-type sugar transport system periplasmic component
CR916_RS18630	COG1609	Transcriptional regulator
CR916_RS18640	COG2311	Membrane
CR916_RS18665	COG4771	TonB-dependent receptor
CR916_RS18675	COG0833	amino acid
CR916_RS18685	COG0583	DNA-binding transcription factor activity
CR916_RS18690	COG2855	membrane
CR916_RS18700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CR916_RS18700	COG1522	sequence-specific DNA binding
CR916_RS18705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CR916_RS18715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CR916_RS18730	COG2313	pseudouridylate synthase activity
CR916_RS18735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CR916_RS18740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS18740	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CR916_RS18740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS18745	COG1105	Belongs to the carbohydrate kinase PfkB family
CR916_RS18750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS18750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS18755	COG2814	Major facilitator Superfamily
CR916_RS18770	COG0246	Mannitol dehydrogenase
CR916_RS18775	COG0523	cobalamin synthesis protein
CR916_RS18780	COG0671	phosphoesterase, PA-phosphatase related
CR916_RS18785	COG0791	NLP P60 protein
CR916_RS18790	COG2200	EAL domain
CR916_RS18795	COG4166	transmembrane transport
CR916_RS18800	COG4174	ABC transporter (Permease)
CR916_RS18805	COG4239	(ABC) transporter, permease
CR916_RS18810	COG4172	Belongs to the ABC transporter superfamily
CR916_RS18825	COG2814	Major facilitator Superfamily
CR916_RS18830	COG1187	pseudouridine synthase activity
CR916_RS18840	COG1061	Type III restriction enzyme res subunit
CR916_RS18860	COG3083	sulfuric ester hydrolase activity
CR916_RS18880	COG2197	response regulator
CR916_RS18885	COG3088	subunit of a heme lyase
CR916_RS18885	COG4235	cytochrome complex assembly
CR916_RS18890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CR916_RS18895	COG1138	Cytochrome C-type biogenesis protein
CR916_RS18905	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CR916_RS18910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CR916_RS18915	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CR916_RS18920	COG4133	protoheme IX ABC transporter activity
CR916_RS18925	COG3005	denitrification pathway
CR916_RS18930	COG3043	anaerobic respiration
CR916_RS18935	COG0348	domain, Protein
CR916_RS18940	COG0437	4 iron, 4 sulfur cluster binding
CR916_RS18950	COG3062	negative regulation of establishment of protein localization
CR916_RS18955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS18955	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS18975	COG4615	Cyclic peptide transporter
CR916_RS18980	COG3145	DNA-N1-methyladenine dioxygenase activity
CR916_RS18985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CR916_RS18985	COG2169	Transcriptional regulator
CR916_RS18990	COG1477	protein flavinylation
CR916_RS18995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CR916_RS19010	COG2198	Histidine kinase
CR916_RS19010	COG0642	Histidine kinase
CR916_RS19015	COG2197	response regulator
CR916_RS19020	COG0784	Response regulator, receiver
CR916_RS19020	COG2205	protein histidine kinase activity
CR916_RS19025	COG4676	Protein conserved in bacteria
CR916_RS19030	COG5445	Predicted secreted protein (DUF2300)
CR916_RS19050	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CR916_RS19055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CR916_RS19065	COG3468	outer membrane autotransporter barrel domain protein
CR916_RS19075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR916_RS19080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR916_RS19085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CR916_RS19090	COG3642	lipopolysaccharide core region biosynthetic process
CR916_RS19095	COG0583	DNA-binding transcription factor activity
CR916_RS19100	COG0584	glycerophosphoryl diester phosphodiesterase
CR916_RS19105	COG2271	Major facilitator Superfamily
CR916_RS19110	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CR916_RS19120	COG0247	lactate metabolic process
CR916_RS19125	COG5464	transposase or invertase
CR916_RS19135	COG2271	Major facilitator Superfamily
CR916_RS19145	COG1414	Transcriptional regulator
CR916_RS19210	COG0318	PFAM AMP-dependent synthetase and ligase
CR916_RS19220	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CR916_RS19235	COG1169	isochorismate synthase
CR916_RS19240	COG4575	ribosome binding
CR916_RS19245	COG2153	protein acetylation
CR916_RS19275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CR916_RS19280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CR916_RS19290	COG0839	Belongs to the complex I subunit 6 family
CR916_RS19305	COG1034	ATP synthesis coupled electron transport
CR916_RS19310	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CR916_RS19315	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CR916_RS19335	COG0583	DNA-binding transcription factor activity
CR916_RS19345	COG0436	Aminotransferase
CR916_RS19355	COG0471	metal ion transport
CR916_RS19355	COG0490	domain, Protein
CR916_RS19360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CR916_RS19375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CR916_RS19380	COG0280	phosphate acetyltransferase
CR916_RS19380	COG0857	belongs to the CobB CobQ family
CR916_RS19385	COG1288	antiporter activity
CR916_RS19390	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CR916_RS19395	COG0622	Phosphoesterase
CR916_RS19400	COG0625	glutathione transferase activity
CR916_RS19405	COG0625	glutathione transferase activity
CR916_RS19410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CR916_RS19415	COG1090	epimerase
CR916_RS19420	COG5464	transposase or invertase
CR916_RS19425	COG4598	ABC transporter
CR916_RS19430	COG4160	amino acid transport
CR916_RS19435	COG4215	(ABC) transporter
CR916_RS19440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR916_RS19445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR916_RS19450	COG0163	prenyltransferase activity
CR916_RS19455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CR916_RS19460	COG1286	toxin biosynthetic process
CR916_RS19465	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CR916_RS19470	COG0285	dihydrofolate synthase activity
CR916_RS19480	COG0586	Pfam SNARE associated Golgi protein
CR916_RS19490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CR916_RS19525	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS19530	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CR916_RS19575	COG2826	transposase and inactivated derivatives, IS30 family
CR916_RS19625	COG2814	Major facilitator Superfamily
CR916_RS19635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CR916_RS19650	COG3101	peptidyl-lysine hydroxylation
CR916_RS19655	COG0730	response to heat
CR916_RS19685	COG3539	Fimbrial protein
CR916_RS19700	COG3539	Fimbrial protein
CR916_RS19705	COG2062	phosphohistidine phosphatase, SixA
CR916_RS19720	COG3691	Protein conserved in bacteria
CR916_RS19730	COG2067	long-chain fatty acid transport protein
CR916_RS19745	COG2853	Lipoprotein
CR916_RS19755	COG2116	formate transmembrane transporter activity
CR916_RS19910	COG3772	lysozyme
CR916_RS19955	COG2207	Transcriptional regulator
CR916_RS19975	COG0484	heat shock protein binding
CR916_RS19980	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CR916_RS20030	COG0305	Participates in initiation and elongation during chromosome replication
CR916_RS20155	COG3561	AntA/AntB antirepressor
CR916_RS20195	COG0582	viral genome integration into host DNA
CR916_RS20415	COG0477	Major facilitator Superfamily
CR916_RS20420	COG1566	PFAM secretion protein HlyD family protein
CR916_RS20425	COG2197	response regulator
CR916_RS20430	COG0784	Response regulator, receiver
CR916_RS20430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR916_RS20430	COG2198	Histidine kinase
CR916_RS20430	COG2205	protein histidine kinase activity
CR916_RS20435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CR916_RS20440	COG0679	Auxin Efflux Carrier
CR916_RS20445	COG0028	Belongs to the TPP enzyme family
CR916_RS20475	COG1560	Kdo2-lipid A biosynthetic process
CR916_RS20485	COG0436	Aminotransferase
CR916_RS20490	COG3275	phosphorelay sensor kinase activity
CR916_RS20495	COG3279	Response regulator of the LytR AlgR family
CR916_RS20510	COG1363	Peptidase, m42
CR916_RS20515	COG0006	proline dipeptidase activity
CR916_RS20520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS20525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS20550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CR916_RS20555	COG2200	EAL domain
CR916_RS20555	COG2199	diguanylate cyclase activity
CR916_RS20570	COG3415	Transposase
CR916_RS20575	COG3415	Transposase
CR916_RS20610	COG0583	DNA-binding transcription factor activity
CR916_RS20615	COG0385	Bile acid
CR916_RS20620	COG3530	Putative quorum-sensing-regulated virulence factor
CR916_RS20640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CR916_RS20645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS20650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CR916_RS20655	COG2190	(PTS) system
CR916_RS20670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CR916_RS20675	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CR916_RS20680	COG4208	sulfate ABC transporter
CR916_RS20685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CR916_RS20690	COG4150	thiosulfate binding
CR916_RS20695	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS20710	COG1263	PTS System
CR916_RS20710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS20715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CR916_RS20720	COG2837	iron assimilation
CR916_RS20740	COG0860	N-Acetylmuramoyl-L-alanine amidase
CR916_RS20750	COG2207	Transcriptional regulator
CR916_RS20755	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CR916_RS20760	COG4816	utilization protein
CR916_RS20770	COG4303	Ethanolamine ammonia lyase large subunit
CR916_RS20775	COG4819	ethanolamine utilization protein
CR916_RS20780	COG3192	ethanolamine utilization protein
CR916_RS20785	COG1454	alcohol dehydrogenase
CR916_RS20790	COG4820	ethanolamine utilization protein (EutJ)
CR916_RS20795	COG1012	belongs to the aldehyde dehydrogenase family
CR916_RS20800	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CR916_RS20805	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CR916_RS20810	COG0280	phosphate acetyltransferase
CR916_RS20815	COG4812	Cobalamin adenosyltransferase
CR916_RS20820	COG4766	ethanolamine catabolic process
CR916_RS20825	COG4917	ethanolamine utilization protein
CR916_RS20830	COG4810	utilization protein
CR916_RS20840	COG0280	phosphate acetyltransferase
CR916_RS20840	COG0281	malic enzyme
CR916_RS20845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CR916_RS20850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CR916_RS20855	COG5342	invasion associated locus B
CR916_RS20865	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS20865	COG0493	'glutamate synthase
CR916_RS20870	COG3850	Histidine kinase
CR916_RS20875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CR916_RS20885	COG1393	Belongs to the ArsC family
CR916_RS20910	COG2321	neutral zinc metallopeptidase
CR916_RS20930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CR916_RS20940	COG2716	regulation of RNA biosynthetic process
CR916_RS20945	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CR916_RS20950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS20960	COG0650	Formate hydrogenlyase subunit 4
CR916_RS20965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CR916_RS20970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CR916_RS20975	COG4237	Hydrogenase 4 membrane
CR916_RS20980	COG0651	ATP synthesis coupled electron transport
CR916_RS20985	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CR916_RS20985	COG3261	NADH dehydrogenase
CR916_RS20995	COG3260	NADH ubiquinone oxidoreductase 20
CR916_RS21010	COG2116	formate transmembrane transporter activity
CR916_RS21020	COG0628	permease
CR916_RS21025	COG4783	chaperone-mediated protein folding
CR916_RS21030	COG1393	Belongs to the ArsC family
CR916_RS21040	COG2233	PERMEase
CR916_RS21060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CR916_RS21065	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CR916_RS21070	COG0248	Ppx GppA phosphatase
CR916_RS21075	COG2200	EAL domain
CR916_RS21095	COG3133	Outer membrane lipoprotein
CR916_RS21110	COG0517	IMP dehydrogenase activity
CR916_RS21110	COG0516	GMP reductase activity
CR916_RS21120	COG1645	bacterial-type flagellum-dependent swarming motility
CR916_RS21135	COG2976	Protein conserved in bacteria
CR916_RS21170	COG4953	penicillin-binding protein 1C
CR916_RS21175	COG2373	Large extracellular alpha-helical protein
CR916_RS21195	COG2975	iron-sulfur cluster assembly
CR916_RS21200	COG0633	Ferredoxin
CR916_RS21220	COG0822	iron-sulfur transferase activity
CR916_RS21240	COG0483	inositol monophosphate 1-phosphatase activity
CR916_RS21245	COG1073	alpha beta
CR916_RS21250	COG3711	transcriptional antiterminator
CR916_RS21255	COG2814	Major facilitator Superfamily
CR916_RS21260	COG0583	DNA-binding transcription factor activity
CR916_RS21265	COG4638	Rieske (2fe-2S)
CR916_RS21290	COG2259	Doxx family
CR916_RS21295	COG2017	converts alpha-aldose to the beta-anomer
CR916_RS21300	COG1063	alcohol dehydrogenase
CR916_RS21305	COG1172	Belongs to the binding-protein-dependent transport system permease family
CR916_RS21310	COG1129	ABC transporter
CR916_RS21315	COG1879	ABC-type sugar transport system periplasmic component
CR916_RS21325	COG1940	carbohydrate kinase activity
CR916_RS21335	COG1017	nitric oxide dioxygenase activity
CR916_RS21335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CR916_RS21340	COG0347	Belongs to the P(II) protein family
CR916_RS21345	COG2204	response regulator
CR916_RS21350	COG3170	Tfp pilus assembly protein FimV
CR916_RS21355	COG2205	protein histidine kinase activity
CR916_RS21380	COG0560	Phosphoserine phosphatase
CR916_RS21385	COG1737	Transcriptional regulator
CR916_RS21390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS21440	COG0681	Belongs to the peptidase S26 family
CR916_RS21450	COG3086	response to oxidative stress
CR916_RS21455	COG3026	antisigma factor binding
CR916_RS21460	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CR916_RS21465	COG1595	DNA-templated transcription, initiation
CR916_RS21470	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CR916_RS21480	COG0513	Belongs to the DEAD box helicase family
CR916_RS21485	COG0583	DNA-binding transcription factor activity
CR916_RS21505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CR916_RS21515	COG3118	belongs to the thioredoxin family
CR916_RS21520	COG3148	PFAM DTW domain containing protein
CR916_RS21525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CR916_RS21525	COG0045	succinate-CoA ligase (ADP-forming) activity
CR916_RS21525	COG1042	CoA-binding domain protein
CR916_RS21530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CR916_RS21535	COG5544	Lipoprotein
CR916_RS21540	COG0477	Major facilitator Superfamily
CR916_RS21570	COG0542	response to heat
CR916_RS21575	COG1496	oxidoreductase activity
CR916_RS21580	COG0564	pseudouridine synthase activity
CR916_RS21585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CR916_RS21595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CR916_RS21605	COG1605	Chorismate mutase
CR916_RS21605	COG0077	Prephenate dehydratase
CR916_RS21610	COG0287	Prephenate dehydrogenase
CR916_RS21610	COG1605	Chorismate mutase
CR916_RS21615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CR916_RS21630	COG2199	diguanylate cyclase activity
CR916_RS21635	COG2885	chlorophyll binding
CR916_RS21660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CR916_RS21665	COG4137	Cytochrome C assembly protein
CR916_RS21670	COG4536	flavin adenine dinucleotide binding
CR916_RS21690	COG0497	DNA recombination
CR916_RS21695	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CR916_RS21705	COG2867	negative regulation of translational initiation
CR916_RS21765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CR916_RS21775	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CR916_RS21875	COG4695	Portal protein
CR916_RS21915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CR916_RS21950	COG4974	Belongs to the 'phage' integrase family
CR916_RS21995	COG5301	cellulose 1,4-beta-cellobiosidase activity
CR916_RS22045	COG1475	DNA binding
CR916_RS22085	COG0366	Alpha amylase catalytic
CR916_RS22095	COG0579	oxidoreductase
CR916_RS22100	COG1012	belongs to the aldehyde dehydrogenase family
CR916_RS22105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CR916_RS22110	COG1113	amino acid transport
CR916_RS22115	COG1802	Transcriptional regulator
CR916_RS22120	COG1652	LysM domain
CR916_RS22125	COG0401	homolog of Blt101
CR916_RS22130	COG0640	Transcriptional regulator
CR916_RS22135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CR916_RS22140	COG2916	Histone family protein nucleoid-structuring protein H-NS
CR916_RS22155	COG4575	ribosome binding
CR916_RS22160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CR916_RS22170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR916_RS22175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR916_RS22180	COG4175	Glycine betaine
CR916_RS22185	COG4176	ABC-type proline glycine betaine transport system permease component
CR916_RS22190	COG2113	Glycine betaine
CR916_RS22200	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CR916_RS22210	COG1846	Transcriptional regulator
CR916_RS22215	COG1566	PFAM secretion protein HlyD family protein
CR916_RS22220	COG2814	Major facilitator Superfamily
CR916_RS22235	COG1238	metal cluster binding
CR916_RS22240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CR916_RS22270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CR916_RS22275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CR916_RS22290	COG1546	Belongs to the CinA family
CR916_RS22295	COG2951	lytic endotransglycosylase activity
CR916_RS22300	COG3730	PTS system glucitol sorbitol-specific
CR916_RS22315	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS22320	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS22325	COG1349	DNA-binding transcription factor activity
CR916_RS22350	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CR916_RS22355	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS22360	COG1609	Transcriptional regulator
CR916_RS22365	COG1263	PTS System
CR916_RS22365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS22370	COG2723	6-phospho-beta-galactosidase activity
CR916_RS22375	COG5499	transcription regulator containing HTH domain
CR916_RS22380	COG4680	protein conserved in bacteria
CR916_RS22390	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CR916_RS22400	COG3260	NADH ubiquinone oxidoreductase 20
CR916_RS22405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CR916_RS22410	COG3261	NADH dehydrogenase
CR916_RS22410	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CR916_RS22415	COG0650	Formate hydrogenlyase subunit 4
CR916_RS22420	COG0651	ATP synthesis coupled electron transport
CR916_RS22425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS22435	COG0375	protein maturation
CR916_RS22440	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CR916_RS22445	COG0298	carbon dioxide binding
CR916_RS22450	COG0409	Hydrogenase expression formation protein
CR916_RS22455	COG0309	Hydrogenase expression formation protein (HypE)
CR916_RS22460	COG3604	Transcriptional regulator
CR916_RS22485	COG1349	DNA-binding transcription factor activity
CR916_RS22490	COG2084	Dehydrogenase
CR916_RS22495	COG3395	kinase activity
CR916_RS22500	COG0235	Class ii aldolase
CR916_RS22505	COG3622	Belongs to the hyi family
CR916_RS22510	COG2610	gluconate transmembrane transporter activity
CR916_RS22520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CR916_RS22535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CR916_RS22540	COG4942	peptidase
CR916_RS22540	COG1388	LysM domain
CR916_RS22595	COG2234	aminopeptidase activity
CR916_RS22600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CR916_RS22620	COG1857	crispr-associated protein
CR916_RS22640	COG1203	CRISPR-associated helicase, Cas3
CR916_RS22670	COG0720	synthase
CR916_RS22675	COG0644	oxidoreductase
CR916_RS22680	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CR916_RS22685	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CR916_RS22690	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CR916_RS22695	COG2086	electron transfer activity
CR916_RS22700	COG0477	Major facilitator Superfamily
CR916_RS22705	COG0277	FAD linked oxidase domain protein
CR916_RS22710	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS22715	COG2223	nitrite transmembrane transporter activity
CR916_RS22720	COG1070	Carbohydrate kinase
CR916_RS22730	COG0602	queuosine metabolic process
CR916_RS22755	COG3956	TIGRFAM MazG family protein
CR916_RS22760	COG2337	Toxic component of a toxin-antitoxin (TA) module
CR916_RS22765	COG2336	PFAM SpoVT AbrB
CR916_RS22770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CR916_RS22780	COG2205	protein histidine kinase activity
CR916_RS22780	COG3437	response regulator, receiver
CR916_RS22780	COG3850	Histidine kinase
CR916_RS22780	COG4999	Histidine kinase
CR916_RS22785	COG4948	Mandelate Racemase Muconate Lactonizing
CR916_RS22790	COG4948	Mandelate Racemase Muconate Lactonizing
CR916_RS22795	COG2271	Major facilitator Superfamily
CR916_RS22800	COG0716	FMN binding
CR916_RS22805	COG0564	pseudouridine synthase activity
CR916_RS22810	COG3098	single-species biofilm formation
CR916_RS22825	COG1611	Belongs to the LOG family
CR916_RS22830	COG0814	amino acid
CR916_RS22835	COG1760	l-serine dehydratase
CR916_RS22845	COG1454	alcohol dehydrogenase
CR916_RS22850	COG0235	Class ii aldolase
CR916_RS22855	COG0738	Major facilitator superfamily
CR916_RS22865	COG1070	Carbohydrate kinase
CR916_RS22875	COG1349	DNA-binding transcription factor activity
CR916_RS22885	COG2363	Small membrane protein
CR916_RS22890	COG0583	DNA-binding transcription factor activity
CR916_RS22900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CR916_RS22905	COG2166	iron-sulfur cluster assembly
CR916_RS22910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CR916_RS22915	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CR916_RS22935	COG0860	N-Acetylmuramoyl-L-alanine amidase
CR916_RS22945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CR916_RS22945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CR916_RS22950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CR916_RS22955	COG1074	ATP-dependent DNA helicase activity
CR916_RS22965	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CR916_RS22970	COG4967	type IV pilus modification protein PilV
CR916_RS22980	COG4795	General secretion pathway protein
CR916_RS22985	COG2165	general secretion pathway protein
CR916_RS23000	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CR916_RS23015	COG0861	Integral membrane protein TerC family
CR916_RS23025	COG0667	Aldo Keto reductase
CR916_RS23040	COG1609	Transcriptional regulator
CR916_RS23050	COG0583	DNA-binding transcription factor activity
CR916_RS23055	COG1794	racemase activity, acting on amino acids and derivatives
CR916_RS23060	COG2814	Major facilitator Superfamily
CR916_RS23065	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS23075	COG0183	Belongs to the thiolase family
CR916_RS23080	COG0814	amino acid
CR916_RS23105	COG0457	Tetratricopeptide repeat
CR916_RS23110	COG3710	Transcriptional regulator
CR916_RS23110	COG0457	Tetratricopeptide repeat
CR916_RS23120	COG3387	PFAM Glycoside hydrolase 15-related
CR916_RS23130	COG4942	peptidase
CR916_RS23145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CR916_RS23150	COG2080	2 iron, 2 sulfur cluster binding
CR916_RS23155	COG3829	transcription factor binding
CR916_RS23160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CR916_RS23170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CR916_RS23180	COG0549	Belongs to the carbamate kinase family
CR916_RS23195	COG0402	S-adenosylhomocysteine deaminase activity
CR916_RS23200	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CR916_RS23205	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CR916_RS23205	COG2080	2 iron, 2 sulfur cluster binding
CR916_RS23210	COG2233	PERMEase
CR916_RS23215	COG0402	S-adenosylhomocysteine deaminase activity
CR916_RS23220	COG2252	PERMEase
CR916_RS23225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS23230	COG0493	'glutamate synthase
CR916_RS23230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS23240	COG2233	PERMEase
CR916_RS23265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CR916_RS23270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CR916_RS23275	COG4974	Belongs to the 'phage' integrase family
CR916_RS23280	COG0716	FMN binding
CR916_RS23290	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CR916_RS23305	COG1272	protein, Hemolysin III
CR916_RS23315	COG2723	6-phospho-beta-galactosidase activity
CR916_RS23320	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS23340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CR916_RS23345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CR916_RS23350	COG0006	proline dipeptidase activity
CR916_RS23375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CR916_RS23395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CR916_RS23415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CR916_RS23415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CR916_RS23420	COG1703	isobutyryl-CoA mutase activity
CR916_RS23425	COG1024	Enoyl-CoA hydratase
CR916_RS23435	COG0583	DNA-binding transcription factor activity
CR916_RS23440	COG2968	Membrane
CR916_RS23450	COG0668	transmembrane transport
CR916_RS23460	COG0191	fructose-bisphosphate aldolase activity
CR916_RS23495	COG1122	ATPase activity
CR916_RS23500	COG1122	ATPase activity
CR916_RS23505	COG1072	(Pantothenic acid kinase))
CR916_RS23515	COG1494	fructose-1,6-bisphosphatase
CR916_RS23520	COG1063	alcohol dehydrogenase
CR916_RS23525	COG2213	PTS system mannitol-specific
CR916_RS23530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS23535	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CR916_RS23540	COG0501	Belongs to the peptidase M48B family
CR916_RS23550	COG1166	arginine decarboxylase activity
CR916_RS23575	COG2814	Major facilitator Superfamily
CR916_RS23585	COG2356	endonuclease I
CR916_RS23590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CR916_RS23595	COG0189	ligase activity
CR916_RS23610	COG2805	Type II/IV secretion system protein
CR916_RS23615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CR916_RS23620	COG0762	integral membrane protein
CR916_RS23635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CR916_RS23655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CR916_RS23670	COG0252	asparaginase activity
CR916_RS23680	COG3171	Protein conserved in bacteria
CR916_RS23695	COG1194	a g-specific adenine glycosylase
CR916_RS23710	COG2211	Major facilitator Superfamily
CR916_RS23715	COG1982	Orn Lys Arg decarboxylase major
CR916_RS23725	COG1811	Na channel or pump
CR916_RS23760	COG3436	PFAM IS66 Orf2 family protein
CR916_RS23775	COG2826	transposase and inactivated derivatives, IS30 family
CR916_RS23800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CR916_RS23805	COG0156	8-amino-7-oxononanoate synthase activity
CR916_RS23815	COG0795	lipopolysaccharide-transporting ATPase activity
CR916_RS23820	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CR916_RS23830	COG2244	polysaccharide biosynthetic process
CR916_RS23835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CR916_RS23840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CR916_RS23845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CR916_RS23850	COG0306	phosphate transporter
CR916_RS23855	COG0754	glutathionylspermidine amidase activity
CR916_RS23860	COG0625	glutathione transferase activity
CR916_RS23865	COG0298	carbon dioxide binding
CR916_RS23875	COG1773	rubredoxin
CR916_RS23880	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CR916_RS23885	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CR916_RS23890	COG5557	Pfam Polysulphide reductase, NrfD
CR916_RS23895	COG0437	4 iron, 4 sulfur cluster binding
CR916_RS23900	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CR916_RS23920	COG0667	Aldo Keto reductase
CR916_RS23930	COG1028	Short-chain dehydrogenase reductase Sdr
CR916_RS23935	COG0848	biopolymer transport protein
CR916_RS23940	COG0811	peptide transport
CR916_RS23950	COG0626	cystathionine gamma-synthase activity
CR916_RS23955	COG0586	Pfam SNARE associated Golgi protein
CR916_RS23960	COG2207	Transcriptional regulator
CR916_RS23965	COG1979	alcohol dehydrogenase
CR916_RS23970	COG0656	L-ascorbic acid biosynthetic process
CR916_RS23980	COG4238	major outer membrane lipoprotein
CR916_RS23985	COG1032	radical SAM domain protein
CR916_RS23990	COG2132	Multicopper oxidase
CR916_RS23995	COG0204	Acyl-transferase
CR916_RS24000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CR916_RS24015	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CR916_RS24020	COG3111	PFAM Bacterial OB fold (BOF) protein
CR916_RS24025	COG0745	RESPONSE REGULATOR receiver
CR916_RS24030	COG0642	Histidine kinase
CR916_RS24035	COG2249	NAD(P)H dehydrogenase (quinone) activity
CR916_RS24040	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CR916_RS24045	COG0187	DNA topoisomerase II activity
CR916_RS24050	COG3150	esterase
CR916_RS24055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CR916_RS24060	COG3151	Protein conserved in bacteria
CR916_RS24065	COG0494	nUDIX hydrolase
CR916_RS24070	COG1538	Outer membrane efflux protein
CR916_RS24085	COG0754	glutathionylspermidine amidase activity
CR916_RS24090	COG3384	dioxygenase
CR916_RS24110	COG2960	long-chain fatty acid transporting porin activity
CR916_RS24115	COG3539	Fimbrial protein
CR916_RS24120	COG3188	usher protein
CR916_RS24125	COG3121	Chaperone
CR916_RS24130	COG3539	Fimbrial protein
CR916_RS24140	COG1585	Membrane protein implicated in regulation of membrane protease activity
CR916_RS24185	COG3025	triphosphatase activity
CR916_RS24195	COG4991	sh3 domain protein
CR916_RS24210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CR916_RS24220	COG0583	DNA-binding transcription factor activity
CR916_RS24230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CR916_RS24235	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CR916_RS24255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CR916_RS24260	COG0358	DNA primase activity
CR916_RS24270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CR916_RS24285	COG2375	cellular response to nickel ion
CR916_RS24295	COG1695	Transcriptional regulator
CR916_RS24300	COG0840	transmembrane signaling receptor activity
CR916_RS24315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR916_RS24325	COG1609	Transcriptional regulator
CR916_RS24330	COG3250	beta-galactosidase activity
CR916_RS24335	COG2731	YhcH YjgK YiaL family protein
CR916_RS24340	COG0531	amino acid
CR916_RS24355	COG1902	pentaerythritol trinitrate reductase activity
CR916_RS24355	COG0446	pyridine nucleotide-disulphide oxidoreductase
CR916_RS24360	COG5499	transcription regulator containing HTH domain
CR916_RS24365	COG4680	protein conserved in bacteria
CR916_RS24380	COG1451	nucleotide metabolic process
CR916_RS24385	COG2949	membrane
CR916_RS24390	COG0673	inositol 2-dehydrogenase activity
CR916_RS24395	COG0861	Integral membrane protein TerC family
CR916_RS24405	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CR916_RS24415	COG2721	sulfolactate sulfo-lyase activity
CR916_RS24455	COG2186	Transcriptional regulator
CR916_RS24460	COG0586	Pfam SNARE associated Golgi protein
CR916_RS24470	COG1422	Protein of unknown function (DUF1090)
CR916_RS24475	COG4575	ribosome binding
CR916_RS24480	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CR916_RS24490	COG2259	Doxx family
CR916_RS24495	COG0435	Glutathione S-transferase
CR916_RS24500	COG3152	Membrane
CR916_RS24510	COG3152	Membrane
CR916_RS24520	COG0583	DNA-binding transcription factor activity
CR916_RS24525	COG1741	Belongs to the pirin family
CR916_RS24540	COG0814	amino acid
CR916_RS24550	COG1760	l-serine dehydratase
CR916_RS24555	COG0251	oxidation-reduction process
CR916_RS24560	COG1882	Formate acetyltransferase
CR916_RS24565	COG1882	Formate acetyltransferase
CR916_RS24570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CR916_RS24580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CR916_RS24590	COG0583	DNA-binding transcription factor activity
CR916_RS24615	COG1929	Belongs to the glycerate kinase type-1 family
CR916_RS24620	COG2084	Dehydrogenase
CR916_RS24630	COG2271	Major facilitator Superfamily
CR916_RS24635	COG2721	sulfolactate sulfo-lyase activity
CR916_RS24640	COG2002	toxin-antitoxin pair type II binding
CR916_RS24650	COG1349	DNA-binding transcription factor activity
CR916_RS24665	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS24675	COG3716	PTS system mannose fructose sorbose family IID component
CR916_RS24680	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS24685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CR916_RS24690	COG2222	sugar isomerase
CR916_RS24700	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS24705	COG3715	PTS system
CR916_RS24710	COG3715	PTS system
CR916_RS24715	COG3716	PTS system mannose fructose sorbose family IID component
CR916_RS24720	COG0363	glucosamine-6-phosphate deaminase activity
CR916_RS24725	COG3539	Fimbrial protein
CR916_RS24730	COG3121	Chaperone
CR916_RS24735	COG3188	usher protein
CR916_RS24740	COG3539	Fimbrial protein
CR916_RS24745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CR916_RS24750	COG3107	peptidoglycan biosynthetic process
CR916_RS24765	COG2823	Periplasmic or secreted lipoprotein
CR916_RS24770	COG0701	Predicted permease
CR916_RS24775	COG0702	epimerase
CR916_RS24780	COG0693	protein deglycase activity
CR916_RS24795	COG3153	acetyltransferase
CR916_RS24800	COG3154	lipid carrier protein
CR916_RS24805	COG0826	peptidase U32
CR916_RS24810	COG0826	peptidase U32
CR916_RS24815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CR916_RS24820	COG0814	amino acid
CR916_RS24825	COG0513	Belongs to the DEAD box helicase family
CR916_RS24870	COG0195	Participates in both transcription termination and antitermination
CR916_RS24900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CR916_RS24910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CR916_RS24915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CR916_RS24925	COG1534	Rna-binding protein
CR916_RS24930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CR916_RS24935	COG2027	D-alanyl-D-alanine carboxypeptidase
CR916_RS24960	COG0142	geranyltranstransferase activity
CR916_RS24965	COG3423	Transcriptional regulator
CR916_RS24975	COG5007	Belongs to the BolA IbaG family
CR916_RS24980	COG3113	response to antibiotic
CR916_RS24985	COG2854	intermembrane phospholipid transfer
CR916_RS24990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CR916_RS24995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CR916_RS25000	COG1127	ABC transporter
CR916_RS25005	COG0530	calcium, potassium:sodium antiporter activity
CR916_RS25010	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CR916_RS25010	COG0517	IMP dehydrogenase activity
CR916_RS25015	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CR916_RS25020	COG3117	lipopolysaccharide transmembrane transporter activity
CR916_RS25025	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CR916_RS25030	COG1137	ATPase activity
CR916_RS25035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CR916_RS25040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CR916_RS25055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS25060	COG0515	serine threonine protein kinase
CR916_RS25070	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CR916_RS25075	COG2198	Histidine kinase
CR916_RS25075	COG5002	protein histidine kinase activity
CR916_RS25075	COG0784	Response regulator, receiver
CR916_RS25080	COG1242	4 iron, 4 sulfur cluster binding
CR916_RS25095	COG0070	glutamate synthase
CR916_RS25095	COG0069	glutamate synthase activity
CR916_RS25095	COG0067	glutamate synthase
CR916_RS25100	COG0493	'glutamate synthase
CR916_RS25115	COG2731	YhcH YjgK YiaL family protein
CR916_RS25155	COG3069	C4-dicarboxylate transmembrane transporter activity
CR916_RS25160	COG2969	positive regulation of protein catabolic process
CR916_RS25165	COG0625	glutathione transferase activity
CR916_RS25190	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CR916_RS25195	COG3105	Protein conserved in bacteria
CR916_RS25200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CR916_RS25205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CR916_RS25225	COG2732	(Barnase) inhibitor
CR916_RS25245	COG0583	DNA-binding transcription factor activity
CR916_RS25250	COG0312	modulator of DNA gyrase
CR916_RS25255	COG3164	Protein of unknown function
CR916_RS25260	COG1530	ribonuclease E activity
CR916_RS25270	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CR916_RS25275	COG1792	Involved in formation and maintenance of cell shape
CR916_RS25280	COG1077	Cell shape determining protein MreB Mrl
CR916_RS25295	COG2199	diguanylate cyclase activity
CR916_RS25295	COG2200	EAL domain
CR916_RS25300	COG0604	alcohol dehydrogenase
CR916_RS25320	COG0511	ligase activity, forming carbon-carbon bonds
CR916_RS25325	COG0439	Biotin carboxylase
CR916_RS25330	COG3924	membrane
CR916_RS25335	COG4145	pantothenate transmembrane transporter activity
CR916_RS25345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CR916_RS25355	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CR916_RS25365	COG1309	transcriptional regulator
CR916_RS25375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CR916_RS25395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR916_RS25400	COG4597	amino acid ABC transporter
CR916_RS25410	COG1126	abc transporter atp-binding protein
CR916_RS25450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CR916_RS25470	COG0551	DNA topoisomerase type I activity
CR916_RS25480	COG0758	DNA mediated transformation
CR916_RS25500	COG0569	domain protein
CR916_RS25510	COG3036	rescue of stalled ribosome
CR916_RS25515	COG0789	Transcriptional regulator
CR916_RS25555	COG0201	protein transport
CR916_RS25645	COG0089	rRNA binding
CR916_RS25725	COG2964	Protein conserved in bacteria
CR916_RS25730	COG0545	Peptidyl-prolyl cis-trans isomerase
CR916_RS25740	COG1047	Peptidyl-prolyl cis-trans
CR916_RS25745	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CR916_RS25765	COG0488	(ABC) transporter
CR916_RS25770	COG0429	hydrolase of the alpha beta-hydrolase fold
CR916_RS25780	COG3954	Phosphoribulokinase
CR916_RS25785	COG1765	OsmC-like protein
CR916_RS25795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CR916_RS25800	COG1289	transmembrane transporter activity
CR916_RS25810	COG0512	Glutamine amidotransferase of anthranilate synthase
CR916_RS25815	COG2184	nucleotidyltransferase activity
CR916_RS25825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CR916_RS25835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CR916_RS25840	COG2146	nitrite reductase [NAD(P)H] activity
CR916_RS25845	COG2116	formate transmembrane transporter activity
CR916_RS25860	COG0531	amino acid
CR916_RS25865	COG2222	sugar isomerase
CR916_RS25875	COG1082	Xylose isomerase domain protein TIM barrel
CR916_RS25885	COG2188	Transcriptional regulator
CR916_RS25890	COG0626	cystathionine gamma-synthase activity
CR916_RS25905	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CR916_RS25925	COG2188	Transcriptional regulator
CR916_RS25930	COG0180	Tryptophanyl-tRNA synthetase
CR916_RS25940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CR916_RS25945	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CR916_RS25950	COG3266	domain, Protein
CR916_RS25970	COG4796	Type ii and iii secretion system protein
CR916_RS25985	COG3166	PFAM Fimbrial assembly family protein
CR916_RS25990	COG4972	Pilus assembly protein
CR916_RS25995	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CR916_RS26000	COG0494	nUDIX hydrolase
CR916_RS26010	COG1011	Hydrolase
CR916_RS26015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CR916_RS26025	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CR916_RS26055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CR916_RS26060	COG2183	response to ionizing radiation
CR916_RS26070	COG1918	ferrous iron import across plasma membrane
CR916_RS26075	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CR916_RS26090	COG5464	transposase or invertase
CR916_RS26100	COG1040	competence protein
CR916_RS26110	COG2610	gluconate transmembrane transporter activity
CR916_RS26115	COG1640	4-alpha-glucanotransferase
CR916_RS26120	COG0058	SHG alpha-glucan phosphorylase activity
CR916_RS26135	COG1690	Belongs to the RtcB family
CR916_RS26140	COG4650	regulator
CR916_RS26145	COG1349	DNA-binding transcription factor activity
CR916_RS26160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CR916_RS26195	COG0058	SHG alpha-glucan phosphorylase activity
CR916_RS26215	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CR916_RS26220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CR916_RS26225	COG2095	MarC family integral membrane protein
CR916_RS26230	COG2610	gluconate transmembrane transporter activity
CR916_RS26235	COG3265	gluconokinase activity
CR916_RS26240	COG1609	Transcriptional regulator
CR916_RS26245	COG1741	Belongs to the pirin family
CR916_RS26250	COG0673	inositol 2-dehydrogenase activity
CR916_RS26260	COG1247	-acetyltransferase
CR916_RS26265	COG3157	Type VI secretion system effector, Hcp
CR916_RS26285	COG0405	Gamma-glutamyltransferase
CR916_RS26295	COG0584	glycerophosphoryl diester phosphodiesterase
CR916_RS26310	COG1175	transmembrane transport
CR916_RS26315	COG1653	transport
CR916_RS26320	COG0410	ABC transporter
CR916_RS26325	COG0411	ABC transporter
CR916_RS26330	COG4177	L-phenylalanine transmembrane transporter activity
CR916_RS26335	COG0559	Belongs to the binding-protein-dependent transport system permease family
CR916_RS26340	COG0683	leucine binding
CR916_RS26350	COG0456	acetyltransferase
CR916_RS26355	COG0683	leucine binding
CR916_RS26360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CR916_RS26365	COG2177	Part of the ABC transporter FtsEX involved in
CR916_RS26370	COG2884	Cell division ATP-binding protein ftsE
CR916_RS26375	COG0552	protein localization to endoplasmic reticulum
CR916_RS26380	COG0742	ribosomal rna small subunit methyltransferase
CR916_RS26385	COG3776	membrane
CR916_RS26395	COG3714	YhhN family
CR916_RS26410	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CR916_RS26425	COG0628	permease
CR916_RS26430	COG2091	lysine biosynthetic process via aminoadipic acid
CR916_RS26435	COG0747	negative chemotaxis
CR916_RS26440	COG0601	transmembrane transport
CR916_RS26445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CR916_RS26450	COG0444	Belongs to the ABC transporter superfamily
CR916_RS26475	COG0842	Transport permease protein
CR916_RS26480	COG0842	Transport permease protein
CR916_RS26480	COG1129	ABC transporter
CR916_RS26485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CR916_RS26520	COG2081	HI0933 family
CR916_RS26525	COG0306	phosphate transporter
CR916_RS26535	COG0589	response to stress
CR916_RS26545	COG3104	oligopeptide transport
CR916_RS26555	COG0339	signal peptide processing
CR916_RS26560	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CR916_RS26565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CR916_RS26580	COG0640	Transcriptional regulator
CR916_RS26585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CR916_RS26590	COG1393	Belongs to the ArsC family
CR916_RS26610	COG3065	identical protein binding
CR916_RS26620	COG2197	response regulator
CR916_RS26625	COG1285	pathogenesis
CR916_RS26640	COG3247	response to pH
CR916_RS26645	COG2771	luxR family
CR916_RS26655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CR916_RS26660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CR916_RS26670	COG2207	Transcriptional regulator
CR916_RS26680	COG0076	glutamate decarboxylase activity
CR916_RS26685	COG1858	cytochrome C peroxidase
CR916_RS26695	COG2197	response regulator
CR916_RS26700	COG0583	DNA-binding transcription factor activity
CR916_RS26705	COG1295	ribonuclease BN
CR916_RS26710	COG0477	Major facilitator Superfamily
CR916_RS26715	COG2982	Protein involved in outer membrane biogenesis
CR916_RS26730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CR916_RS26735	COG0612	Peptidase, M16
CR916_RS26750	COG2200	EAL domain
CR916_RS26750	COG2199	diguanylate cyclase activity
CR916_RS26755	COG0457	Tetratricopeptide repeat
CR916_RS26755	COG3118	belongs to the thioredoxin family
CR916_RS26760	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CR916_RS26805	COG2194	sulfuric ester hydrolase activity
CR916_RS26845	COG0814	amino acid
CR916_RS26850	COG4608	Belongs to the ABC transporter superfamily
CR916_RS26855	COG0444	Belongs to the ABC transporter superfamily
CR916_RS26860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CR916_RS26865	COG0601	transmembrane transport
CR916_RS26870	COG0747	negative chemotaxis
CR916_RS26885	COG2194	sulfuric ester hydrolase activity
CR916_RS26890	COG2223	nitrite transmembrane transporter activity
CR916_RS26900	COG5571	outer membrane autotransporter
CR916_RS26905	COG2818	Glycosylase
CR916_RS26910	COG0456	acetyltransferase
CR916_RS26930	COG2885	chlorophyll binding
CR916_RS26945	COG2944	sequence-specific DNA binding
CR916_RS26950	COG1278	Cold shock
CR916_RS26975	COG3274	enterobacterial common antigen metabolic process
CR916_RS26985	COG4682	membrane
CR916_RS26990	COG1070	Carbohydrate kinase
CR916_RS27000	COG4213	ABC transporter substrate-binding protein
CR916_RS27010	COG4214	carbohydrate transport
CR916_RS27015	COG1609	Transcriptional regulator
CR916_RS27015	COG2207	Transcriptional regulator
CR916_RS27020	COG2992	FlgJ-related protein
CR916_RS27025	COG0366	Alpha amylase catalytic
CR916_RS27030	COG3977	Valine--pyruvate aminotransferase
CR916_RS27035	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CR916_RS27040	COG1414	Transcriptional regulator
CR916_RS27065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CR916_RS27075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CR916_RS27080	COG1070	Carbohydrate kinase
CR916_RS27085	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CR916_RS27090	COG3623	hexulose-6-phosphate isomerase
CR916_RS27095	COG0235	Class ii aldolase
CR916_RS27105	COG3713	MltA-interacting MipA family protein
CR916_RS27110	COG0583	DNA-binding transcription factor activity
CR916_RS27115	COG1566	PFAM secretion protein HlyD family protein
CR916_RS27130	COG1012	belongs to the aldehyde dehydrogenase family
CR916_RS27150	COG3276	selenocysteine insertion sequence binding
CR916_RS27160	COG0625	glutathione transferase activity
CR916_RS27165	COG3209	COG3209 Rhs family protein
CR916_RS27170	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CR916_RS27190	COG1566	PFAM secretion protein HlyD family protein
CR916_RS27200	COG2213	PTS system mannitol-specific
CR916_RS27200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS27210	COG3722	fumarate hydratase activity
CR916_RS27235	COG5295	Hep Hag repeat protein
CR916_RS27245	COG1620	l-lactate permease
CR916_RS27250	COG2186	Transcriptional regulator
CR916_RS27260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CR916_RS27265	COG1045	serine acetyltransferase
CR916_RS27280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CR916_RS27285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CR916_RS27300	COG4942	peptidase
CR916_RS27305	COG2861	carbohydrate metabolic process
CR916_RS27320	COG0156	8-amino-7-oxononanoate synthase activity
CR916_RS27335	COG0859	PFAM glycosyl transferase family 9
CR916_RS27340	COG0859	PFAM glycosyl transferase family 9
CR916_RS27360	COG3642	lipopolysaccharide core region biosynthetic process
CR916_RS27370	COG0515	serine threonine protein kinase
CR916_RS27375	COG0438	transferase activity, transferring glycosyl groups
CR916_RS27380	COG0859	PFAM glycosyl transferase family 9
CR916_RS27385	COG1519	Transferase
CR916_RS27415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CR916_RS27445	COG1561	YicC-like family, N-terminal region
CR916_RS27530	COG2391	methyltransferase activity
CR916_RS27550	COG3645	SOS response
CR916_RS27555	COG2860	membrane
CR916_RS27565	COG0194	GDP metabolic process
CR916_RS27575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CR916_RS27580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CR916_RS27585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CR916_RS27595	COG0786	glutamate:sodium symporter activity
CR916_RS27600	COG2233	PERMEase
CR916_RS27605	COG2982	Protein involved in outer membrane biogenesis
CR916_RS27610	COG1501	Belongs to the glycosyl hydrolase 31 family
CR916_RS27615	COG2211	Major facilitator Superfamily
CR916_RS27660	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CR916_RS27675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CR916_RS27690	COG2814	Major facilitator Superfamily
CR916_RS27695	COG0697	spore germination
CR916_RS27700	COG1464	Belongs to the NlpA lipoprotein family
CR916_RS27730	COG2252	PERMEase
CR916_RS27740	COG2271	Major facilitator Superfamily
CR916_RS27745	COG2271	Major facilitator Superfamily
CR916_RS27750	COG3851	Histidine kinase
CR916_RS27755	COG2197	response regulator
CR916_RS27760	COG0440	acetolactate synthase activity
CR916_RS27765	COG0028	Belongs to the TPP enzyme family
CR916_RS27800	COG2814	Major facilitator Superfamily
CR916_RS27805	COG0641	radical SAM
CR916_RS27815	COG2149	membrane
CR916_RS27825	COG3119	arylsulfatase activity
CR916_RS27830	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CR916_RS27835	COG2207	Transcriptional regulator
CR916_RS27850	COG2188	Transcriptional regulator
CR916_RS27870	COG5645	(Lipo)protein
CR916_RS27875	COG0823	Involved in the tonB-independent uptake of proteins
CR916_RS27885	COG2271	Major facilitator Superfamily
CR916_RS27895	COG0800	Aldolase
CR916_RS27900	COG3734	2-keto-3-deoxy-galactonokinase
CR916_RS27905	COG2186	Transcriptional regulator
CR916_RS27915	COG0561	phosphatase activity
CR916_RS27920	COG3753	Protein conserved in bacteria
CR916_RS27925	COG0187	DNA topoisomerase II activity
CR916_RS27935	COG0592	DNA-directed DNA polymerase activity
CR916_RS27985	COG0814	amino acid
CR916_RS28000	COG2091	lysine biosynthetic process via aminoadipic acid
CR916_RS28005	COG0431	NADPH-dependent FMN reductase
CR916_RS28010	COG2252	PERMEase
CR916_RS28015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CR916_RS28025	COG3196	Protein conserved in bacteria
CR916_RS28030	COG0363	glucosamine-6-phosphate deaminase activity
CR916_RS28035	COG2382	esterase
CR916_RS28045	COG2723	6-phospho-beta-galactosidase activity
CR916_RS28050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR916_RS28050	COG1263	PTS System
CR916_RS28050	COG2190	(PTS) system
CR916_RS28055	COG3711	transcriptional antiterminator
CR916_RS28065	COG0704	Plays a role in the regulation of phosphate uptake
CR916_RS28070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CR916_RS28075	COG0581	inorganic phosphate transmembrane transporter activity
CR916_RS28080	COG0573	inorganic phosphate transmembrane transporter activity
CR916_RS28085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CR916_RS28105	COG3539	Fimbrial protein
CR916_RS28160	COG3312	ion transport
CR916_RS28175	COG0716	FMN binding
CR916_RS28180	COG1522	sequence-specific DNA binding
CR916_RS28210	COG1129	ABC transporter
CR916_RS28215	COG1172	Belongs to the binding-protein-dependent transport system permease family
CR916_RS28220	COG1879	ABC-type sugar transport system periplasmic component
CR916_RS28225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CR916_RS28230	COG1609	Transcriptional regulator
CR916_RS28235	COG0477	Major facilitator Superfamily
CR916_RS28240	COG2186	Transcriptional regulator
CR916_RS28280	COG3085	chromosome segregation
CR916_RS28285	COG0606	chelatase, subunit chli
CR916_RS28310	COG3978	acetolactate synthase activity
CR916_RS28315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CR916_RS28325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CR916_RS28330	COG0583	DNA-binding transcription factor activity
CR916_RS28340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CR916_RS28345	COG3692	DNA binding
CR916_RS28350	COG0210	DNA helicase
CR916_RS28370	COG3118	belongs to the thioredoxin family
CR916_RS28380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CR916_RS28390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CR916_RS28395	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CR916_RS28400	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CR916_RS28405	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CR916_RS28410	COG1088	dTDP-glucose 4,6-dehydratase activity
CR916_RS28415	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CR916_RS28420	COG0456	acetyltransferase
CR916_RS28425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CR916_RS28430	COG2244	polysaccharide biosynthetic process
CR916_RS28450	COG1113	amino acid transport
CR916_RS28475	COG0641	radical SAM
CR916_RS28480	COG3071	HemY protein
CR916_RS28485	COG2959	enzyme of heme biosynthesis
CR916_RS28490	COG1587	Uroporphyrinogen-III synthase
CR916_RS28505	COG3072	Adenylate cyclase
CR916_RS28515	COG5567	small periplasmic lipoprotein
CR916_RS28525	COG3159	Protein conserved in bacteria
CR916_RS28535	COG1011	Hydrolase
CR916_RS28540	COG0210	DNA helicase
CR916_RS28545	COG3698	Phosphodiester glycosidase
CR916_RS28550	COG0598	Magnesium transport protein CorA
CR916_RS28565	COG2962	Rard protein
CR916_RS28570	COG2050	protein possibly involved in aromatic compounds catabolism
CR916_RS28575	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CR916_RS28580	COG0514	ATP-dependent DNA helicase (RecQ)
CR916_RS28585	COG1280	lysine exporter protein (LysE YggA)
CR916_RS28590	COG1280	lysine exporter protein (LysE YggA)
CR916_RS28595	COG2267	carboxylic ester hydrolase activity
CR916_RS28600	COG0561	phosphatase activity
CR916_RS28605	COG0697	spore germination
CR916_RS28610	COG0583	DNA-binding transcription factor activity
CR916_RS28620	COG0412	Dienelactone hydrolase
CR916_RS28625	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CR916_RS28630	COG1322	Protein conserved in bacteria
CR916_RS28640	COG3165	ubiquinone biosynthetic process from chorismate
CR916_RS28650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CR916_RS28655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CR916_RS28660	COG0805	protein transport
CR916_RS28670	COG0250	Participates in transcription elongation, termination and antitermination
CR916_RS28675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CR916_RS28680	COG0543	2 iron, 2 sulfur cluster binding
CR916_RS28700	COG1739	Uncharacterized protein family UPF0029
CR916_RS28705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CR916_RS28710	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CR916_RS28745	COG0746	molybdenum cofactor guanylyltransferase activity
CR916_RS28750	COG3084	Protein conserved in bacteria
CR916_RS28755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CR916_RS28760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CR916_RS28765	COG5339	Protein conserved in bacteria
CR916_RS28770	COG0204	Acyl-transferase
CR916_RS28780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR916_RS28780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR916_RS28795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CR916_RS28805	COG2204	response regulator
CR916_RS28810	COG3852	Histidine kinase
CR916_RS28815	COG0174	glutamine synthetase
CR916_RS28825	COG1217	gtp-binding protein TYPA
CR916_RS28830	COG2188	Transcriptional regulator
CR916_RS28835	COG1082	Xylose isomerase domain protein TIM barrel
CR916_RS28840	COG2271	Major facilitator Superfamily
CR916_RS28850	COG2211	Major facilitator Superfamily
CR916_RS28855	COG2211	Major facilitator Superfamily
CR916_RS28860	COG1501	Belongs to the glycosyl hydrolase 31 family
CR916_RS28865	COG2017	converts alpha-aldose to the beta-anomer
CR916_RS28870	COG2942	2-epimerase
CR916_RS28875	COG3684	Belongs to the aldolase LacD family
CR916_RS28880	COG2084	Dehydrogenase
CR916_RS28885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CR916_RS28890	COG1349	DNA-binding transcription factor activity
CR916_RS28895	COG1011	Hydrolase
CR916_RS28910	COG0456	acetyltransferase
CR916_RS28915	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CR916_RS28920	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CR916_RS28930	COG2864	formate dehydrogenase
CR916_RS28935	COG0437	4 iron, 4 sulfur cluster binding
CR916_RS28960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS28960	COG3711	transcriptional antiterminator
CR916_RS28965	COG1363	Peptidase, m42
CR916_RS28970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS28970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS28975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR916_RS29015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CR916_RS29030	COG2258	MOSC domain
CR916_RS29035	COG2205	protein histidine kinase activity
CR916_RS29040	COG0745	RESPONSE REGULATOR receiver
CR916_RS29045	COG3678	ATP-independent chaperone mediated protein folding
CR916_RS29060	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CR916_RS29080	COG3152	Membrane
CR916_RS29085	COG3691	Protein conserved in bacteria
CR916_RS29090	COG0589	response to stress
CR916_RS29100	COG1494	fructose-1,6-bisphosphatase
CR916_RS29110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CR916_RS29125	COG1575	Belongs to the MenA family. Type 1 subfamily
CR916_RS29140	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CR916_RS29145	COG1609	Transcriptional regulator
CR916_RS29150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CR916_RS29170	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CR916_RS29180	COG0626	cystathionine gamma-synthase activity
CR916_RS29185	COG0527	aspartate kinase activity
CR916_RS29185	COG0460	homoserine dehydrogenase
CR916_RS29190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CR916_RS29200	COG0697	spore germination
CR916_RS29205	COG3738	Protein conserved in bacteria
CR916_RS29210	COG0371	Dehydrogenase
CR916_RS29215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CR916_RS29230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS29235	COG1882	Formate acetyltransferase
CR916_RS29240	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CR916_RS29245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR916_RS29250	COG2207	Transcriptional regulator
CR916_RS29255	COG2194	sulfuric ester hydrolase activity
CR916_RS29270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CR916_RS29285	COG0583	DNA-binding transcription factor activity
CR916_RS29315	COG4206	TonB-dependent receptor
CR916_RS29350	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CR916_RS29350	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CR916_RS29395	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CR916_RS29400	COG0250	Participates in transcription elongation, termination and antitermination
CR916_RS29455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CR916_RS29465	COG2104	thiamine diphosphate biosynthetic process
CR916_RS29470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CR916_RS29510	COG3068	Protein conserved in bacteria
CR916_RS29525	COG3678	ATP-independent chaperone mediated protein folding
CR916_RS29535	COG4191	Histidine kinase
CR916_RS29540	COG2204	response regulator
CR916_RS29545	COG0151	Belongs to the GarS family
CR916_RS29580	COG0456	acetyltransferase
CR916_RS29590	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CR916_RS29595	COG2224	Isocitrate lyase
CR916_RS29610	COG1414	Transcriptional regulator
CR916_RS29615	COG0646	methionine synthase
CR916_RS29615	COG1410	methionine synthase
CR916_RS29620	COG1283	sodium-dependent phosphate transmembrane transporter activity
CR916_RS29675	COG0527	aspartate kinase activity
CR916_RS29710	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CR916_RS29725	COG2814	Major facilitator Superfamily
CR916_RS29725	COG0477	Major facilitator Superfamily
CR916_RS29730	COG3833	ABC-type maltose transport systems, permease component
CR916_RS29735	COG1175	transmembrane transport
CR916_RS29740	COG2182	Extracellular solute-binding protein
CR916_RS29750	COG3842	ATPase activity
CR916_RS29795	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CR916_RS29805	COG0534	Mate efflux family protein
CR916_RS29810	COG3237	CsbD-like
CR916_RS29815	COG0735	belongs to the Fur family
CR916_RS29830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CR916_RS29880	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CR916_RS29885	COG5532	Uncharacterized conserved protein (DUF2303)
CR916_RS29905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CR916_RS29910	COG4197	protein conserved in bacteria, prophage-related