locus-tag	class	description
SG48_RS00010	COG0460	homoserine dehydrogenase
SG48_RS00010	COG0527	aspartate kinase activity
SG48_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SG48_RS00040	COG1115	amino acid carrier protein
SG48_RS00045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SG48_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
SG48_RS00055	COG1584	GPR1 FUN34 yaaH family protein
SG48_RS00060	COG4735	regulation of single-species biofilm formation
SG48_RS00080	COG3385	transposase activity
SG48_RS00090	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SG48_RS00095	COG0583	DNA-binding transcription factor activity
SG48_RS00120	COG0196	riboflavin kinase activity
SG48_RS00135	COG1047	Peptidyl-prolyl cis-trans
SG48_RS00165	COG0505	Belongs to the CarA family
SG48_RS00170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SG48_RS00225	COG0644	oxidoreductase
SG48_RS00230	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SG48_RS00235	COG2271	Major facilitator Superfamily
SG48_RS00250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SG48_RS00275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SG48_RS00280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SG48_RS00285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SG48_RS00295	COG0564	pseudouridine synthase activity
SG48_RS00305	COG0417	DNA replication proofreading
SG48_RS00310	COG0235	Class ii aldolase
SG48_RS00315	COG2160	L-arabinose isomerase activity
SG48_RS00320	COG1069	ribulokinase activity
SG48_RS00325	COG4977	sequence-specific DNA binding
SG48_RS00330	COG0586	Pfam SNARE associated Golgi protein
SG48_RS00335	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SG48_RS00340	COG1178	ABC-type Fe3 transport system permease component
SG48_RS00345	COG4143	(ABC) transporter
SG48_RS00350	COG4533	DNA binding
SG48_RS00360	COG2814	Major facilitator Superfamily
SG48_RS00375	COG0473	3-isopropylmalate dehydrogenase activity
SG48_RS00390	COG0583	DNA-binding transcription factor activity
SG48_RS00395	COG0028	Belongs to the TPP enzyme family
SG48_RS00400	COG0440	acetolactate synthase activity
SG48_RS00410	COG1609	Transcriptional regulator
SG48_RS00415	COG2001	Belongs to the MraZ family
SG48_RS00425	COG3116	cell division
SG48_RS00430	COG0768	penicillin binding
SG48_RS00435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SG48_RS00440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SG48_RS00450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SG48_RS00455	COG0772	Belongs to the SEDS family
SG48_RS00470	COG1181	Belongs to the D-alanine--D-alanine ligase family
SG48_RS00475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SG48_RS00480	COG0849	cell division
SG48_RS00485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SG48_RS00505	COG0494	nUDIX hydrolase
SG48_RS00525	COG0237	dephospho-CoA kinase activity
SG48_RS00535	COG1459	type II secretion system
SG48_RS00540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SG48_RS00545	COG4969	Belongs to the N-Me-Phe pilin family
SG48_RS00555	COG0157	Belongs to the NadC ModD family
SG48_RS00560	COG3023	N-Acetylmuramoyl-L-alanine amidase
SG48_RS00565	COG3725	Membrane protein required for beta-lactamase induction
SG48_RS00570	COG1113	amino acid transport
SG48_RS00575	COG2186	Transcriptional regulator
SG48_RS00580	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SG48_RS00585	COG0508	dehydrogenase complex catalyzes the overall conversion of
SG48_RS00590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SG48_RS00595	COG3064	Membrane
SG48_RS00600	COG1049	propionate catabolic process, 2-methylcitrate cycle
SG48_RS00625	COG2132	Multicopper oxidase
SG48_RS00630	COG4993	Dehydrogenase
SG48_RS00635	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SG48_RS00640	COG0288	reversible hydration of carbon dioxide
SG48_RS00645	COG1131	(ABC) transporter
SG48_RS00650	COG0842	Transport permease protein
SG48_RS00655	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS00660	COG0726	polysaccharide deacetylase
SG48_RS00670	COG5464	transposase or invertase
SG48_RS00685	COG3539	Fimbrial protein
SG48_RS00690	COG3539	Fimbrial protein
SG48_RS00695	COG3539	Fimbrial protein
SG48_RS00700	COG3539	Fimbrial protein
SG48_RS00705	COG3188	usher protein
SG48_RS00710	COG3121	Chaperone
SG48_RS00715	COG3539	Fimbrial protein
SG48_RS00720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SG48_RS00725	COG0617	tRNA 3'-terminal CCA addition
SG48_RS00735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SG48_RS00745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SG48_RS00750	COG1643	Atp-dependent helicase
SG48_RS00760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SG48_RS00765	COG4774	siderophore transport
SG48_RS00770	COG1120	ATPase activity
SG48_RS00775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SG48_RS00780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SG48_RS00800	COG2860	membrane
SG48_RS00805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SG48_RS00820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SG48_RS00825	COG3835	regulator
SG48_RS00835	COG1408	metallophosphoesterase
SG48_RS00850	COG0024	Methionine aminopeptidase
SG48_RS00875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SG48_RS00880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SG48_RS00885	COG0575	Belongs to the CDS family
SG48_RS00890	COG0750	zinc metalloprotease
SG48_RS00900	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
SG48_RS00905	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SG48_RS00930	COG0587	DNA-directed DNA polymerase activity
SG48_RS00940	COG1982	Orn Lys Arg decarboxylase major
SG48_RS00945	COG0346	lactoylglutathione lyase activity
SG48_RS00950	COG0037	tRNA processing
SG48_RS00955	COG4568	rho-dependent transcription termination
SG48_RS00965	COG4681	YaeQ
SG48_RS00970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SG48_RS00975	COG3015	lipoprotein NlpE involved in copper resistance
SG48_RS00980	COG0791	NLP P60 protein
SG48_RS00990	COG1720	tRNA m6t6A37 methyltransferase activity
SG48_RS01000	COG1464	Belongs to the NlpA lipoprotein family
SG48_RS01005	COG2011	ABC-type metal ion transport system permease component
SG48_RS01010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SG48_RS01015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SG48_RS01050	COG0656	L-ascorbic acid biosynthetic process
SG48_RS01055	COG0583	DNA-binding transcription factor activity
SG48_RS01065	COG2226	methyltransferase
SG48_RS01070	COG1388	LysM domain
SG48_RS01070	COG0741	lytic transglycosylase activity
SG48_RS01080	COG2226	methyltransferase
SG48_RS01090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SG48_RS01110	COG4104	PAAR repeat-containing protein
SG48_RS01115	COG5433	transposase activity
SG48_RS01120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SG48_RS01130	COG1960	acyl-CoA dehydrogenase activity
SG48_RS01140	COG0121	glutamine amidotransferase
SG48_RS01145	COG3034	peptidoglycan biosynthetic process
SG48_RS01150	COG3041	Addiction module toxin RelE StbE family
SG48_RS01155	COG3077	Addiction module antitoxin, RelB DinJ family
SG48_RS01160	COG0791	NLP P60 protein
SG48_RS01165	COG1943	Transposase
SG48_RS01185	COG2161	toxin-antitoxin pair type II binding
SG48_RS01195	COG0454	-acetyltransferase
SG48_RS01200	COG1690	Belongs to the RtcB family
SG48_RS01205	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SG48_RS01210	COG2195	Cleaves the N-terminal amino acid of tripeptides
SG48_RS01230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SG48_RS01260	COG2003	Belongs to the UPF0758 family
SG48_RS01280	COG2378	regulation of single-species biofilm formation
SG48_RS01295	COG3596	GTP binding
SG48_RS01300	COG0583	DNA-binding transcription factor activity
SG48_RS01305	COG2963	transposase activity
SG48_RS01310	COG2826	transposase and inactivated derivatives, IS30 family
SG48_RS01315	COG2801	Transposase and inactivated derivatives
SG48_RS01330	COG3344	reverse transcriptase
SG48_RS01340	COG0833	amino acid
SG48_RS01345	COG2040	homocysteine
SG48_RS01350	COG3842	ATPase activity
SG48_RS01355	COG1178	ABC-type Fe3 transport system permease component
SG48_RS01360	COG1662	PFAM IS1 transposase
SG48_RS01365	COG1662	PFAM IS1 transposase
SG48_RS01365	COG3677	Transposase
SG48_RS01370	COG2963	transposase activity
SG48_RS01380	COG3415	Transposase
SG48_RS01380	COG2801	Transposase and inactivated derivatives
SG48_RS01385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SG48_RS01390	COG0129	dihydroxy-acid dehydratase activity
SG48_RS01395	COG2211	Major facilitator Superfamily
SG48_RS01400	COG3507	Belongs to the glycosyl hydrolase 43 family
SG48_RS01405	COG1414	Transcriptional regulator
SG48_RS01410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SG48_RS01415	COG1662	PFAM IS1 transposase
SG48_RS01420	COG1061	Type III restriction enzyme res subunit
SG48_RS01430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SG48_RS01450	COG0582	viral genome integration into host DNA
SG48_RS01460	COG0583	DNA-binding transcription factor activity
SG48_RS01465	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SG48_RS01470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SG48_RS01475	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SG48_RS01480	COG2080	2 iron, 2 sulfur cluster binding
SG48_RS01485	COG3477	response to acidic pH
SG48_RS01490	COG0727	PFAM Uncharacterised protein family (UPF0153)
SG48_RS01495	COG3121	Chaperone
SG48_RS01505	COG3188	usher protein
SG48_RS01545	COG1388	LysM domain
SG48_RS01555	COG2801	Transposase and inactivated derivatives
SG48_RS01560	COG3708	Transcriptional regulator
SG48_RS01560	COG2207	Transcriptional regulator
SG48_RS01565	COG3059	membrane
SG48_RS01575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SG48_RS01580	COG2207	Transcriptional regulator
SG48_RS01585	COG0247	lactate metabolic process
SG48_RS01590	COG1139	Iron-sulfur cluster binding protein
SG48_RS01595	COG1556	Lactate utilization protein
SG48_RS01625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SG48_RS01635	COG2771	luxR family
SG48_RS01635	COG2200	EAL domain
SG48_RS01640	COG0583	DNA-binding transcription factor activity
SG48_RS01650	COG0666	response to abiotic stimulus
SG48_RS01660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SG48_RS01665	COG1304	FMN binding
SG48_RS01675	COG0549	Belongs to the carbamate kinase family
SG48_RS01680	COG0402	S-adenosylhomocysteine deaminase activity
SG48_RS01685	COG1064	alcohol dehydrogenase
SG48_RS01700	COG1280	lysine exporter protein (LysE YggA)
SG48_RS01710	COG3829	transcription factor binding
SG48_RS01715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SG48_RS01720	COG0372	Belongs to the citrate synthase family
SG48_RS01725	COG2079	MmgE PrpD family protein
SG48_RS01730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SG48_RS01735	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SG48_RS01740	COG0402	S-adenosylhomocysteine deaminase activity
SG48_RS01745	COG0583	DNA-binding transcription factor activity
SG48_RS01750	COG0288	reversible hydration of carbon dioxide
SG48_RS01760	COG2807	transmembrane transport
SG48_RS01765	COG0110	maltose O-acetyltransferase activity
SG48_RS01770	COG2223	nitrite transmembrane transporter activity
SG48_RS01775	COG3250	beta-galactosidase activity
SG48_RS01780	COG1609	Transcriptional regulator
SG48_RS01785	COG1414	Transcriptional regulator
SG48_RS01805	COG3971	2-oxopent-4-enoate hydratase activity
SG48_RS01820	COG2814	Major facilitator Superfamily
SG48_RS01825	COG3122	Protein conserved in bacteria
SG48_RS01835	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SG48_RS01870	COG1215	transferase activity, transferring glycosyl groups
SG48_RS01875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SG48_RS01880	COG4521	taurine ABC transporter
SG48_RS01890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SG48_RS01895	COG2175	clavaminate synthase activity
SG48_RS01900	COG0113	porphobilinogen synthase activity
SG48_RS01915	COG2801	Transposase and inactivated derivatives
SG48_RS01925	COG3468	outer membrane autotransporter barrel domain protein
SG48_RS01930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SG48_RS01935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SG48_RS01945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
SG48_RS01965	COG1181	Belongs to the D-alanine--D-alanine ligase family
SG48_RS01980	COG1785	Belongs to the alkaline phosphatase family
SG48_RS01990	COG3706	GGDEF domain
SG48_RS01995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SG48_RS02020	COG4126	flavin adenine dinucleotide binding
SG48_RS02040	COG1940	carbohydrate kinase activity
SG48_RS02045	COG2814	Major facilitator Superfamily
SG48_RS02050	COG0419	ATPase involved in DNA repair
SG48_RS02055	COG0420	3'-5' exonuclease activity
SG48_RS02060	COG0745	RESPONSE REGULATOR receiver
SG48_RS02065	COG5002	protein histidine kinase activity
SG48_RS02070	COG1114	Component of the transport system for branched-chain amino acids
SG48_RS02075	COG1113	amino acid transport
SG48_RS02080	COG0366	Alpha amylase catalytic
SG48_RS02100	COG1862	Preprotein translocase
SG48_RS02105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SG48_RS02110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SG48_RS02115	COG1403	HNH endonuclease
SG48_RS02125	COG3248	Nucleoside-binding outer membrane protein
SG48_RS02130	COG4238	major outer membrane lipoprotein
SG48_RS02140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SG48_RS02140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SG48_RS02155	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SG48_RS02160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SG48_RS02165	COG0667	Aldo Keto reductase
SG48_RS02175	COG0142	geranyltranstransferase activity
SG48_RS02190	COG0693	protein deglycase activity
SG48_RS02195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SG48_RS02205	COG2814	Major facilitator Superfamily
SG48_RS02215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SG48_RS02220	COG1845	cytochrome c oxidase, subunit III
SG48_RS02225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SG48_RS02230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SG48_RS02235	COG2223	nitrite transmembrane transporter activity
SG48_RS02240	COG3056	Lipoprotein
SG48_RS02245	COG0271	Belongs to the BolA IbaG family
SG48_RS02270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SG48_RS02275	COG0776	regulation of translation
SG48_RS02280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SG48_RS02285	COG1555	photosystem II stabilization
SG48_RS02290	COG0824	Thioesterase
SG48_RS02300	COG4533	DNA binding
SG48_RS02310	COG1522	sequence-specific DNA binding
SG48_RS02315	COG1132	(ABC) transporter
SG48_RS02320	COG1132	(ABC) transporter
SG48_RS02325	COG0347	Belongs to the P(II) protein family
SG48_RS02330	COG0004	ammonium transporteR
SG48_RS02335	COG1946	Acyl-CoA thioesterase
SG48_RS02340	COG3126	Type III secretion system lipoprotein chaperone (YscW)
SG48_RS02345	COG3695	enzyme binding
SG48_RS02350	COG5507	3-demethylubiquinone-9 3-methyltransferase
SG48_RS02355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SG48_RS02365	COG0110	maltose O-acetyltransferase activity
SG48_RS02380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SG48_RS02385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SG48_RS02390	COG1309	transcriptional regulator
SG48_RS02395	COG1196	nuclear chromosome segregation
SG48_RS02395	COG3264	Mechanosensitive ion channel
SG48_RS02410	COG3923	Primosomal replication protein n
SG48_RS02415	COG2832	Protein of unknown function (DUF454)
SG48_RS02425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SG48_RS02460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SG48_RS02465	COG4651	solute:proton antiporter activity
SG48_RS02465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SG48_RS02470	COG2223	nitrite transmembrane transporter activity
SG48_RS02475	COG0737	Belongs to the 5'-nucleotidase family
SG48_RS02480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SG48_RS02485	COG3735	TraB family
SG48_RS02490	COG3093	addiction module antidote protein HigA
SG48_RS02495	COG2217	Heavy metal translocating P-type atpase
SG48_RS02500	COG2066	Belongs to the glutaminase family
SG48_RS02505	COG0531	amino acid
SG48_RS02510	COG0789	Transcriptional regulator
SG48_RS02515	COG1585	Membrane protein implicated in regulation of membrane protease activity
SG48_RS02520	COG0330	HflC and HflK could
SG48_RS02525	COG4619	ABC transporter
SG48_RS02530	COG0390	transport system, permease component
SG48_RS02535	COG3118	belongs to the thioredoxin family
SG48_RS02540	COG0300	oxidoreductase activity
SG48_RS02545	COG2755	lipolytic protein G-D-S-L family
SG48_RS02550	COG4181	ATPase activity
SG48_RS02555	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
SG48_RS02560	COG3209	COG3209 Rhs family protein
SG48_RS02570	COG3209	COG3209 Rhs family protein
SG48_RS02580	COG2801	Transposase and inactivated derivatives
SG48_RS02590	COG0583	DNA-binding transcription factor activity
SG48_RS02600	COG1414	Transcriptional regulator
SG48_RS02605	COG3960	tartronate-semialdehyde synthase activity
SG48_RS02610	COG3622	Belongs to the hyi family
SG48_RS02615	COG2084	Dehydrogenase
SG48_RS02620	COG1953	Uracil, thiamine, allantoin
SG48_RS02630	COG2233	PERMEase
SG48_RS02635	COG1929	Belongs to the glycerate kinase type-1 family
SG48_RS02640	COG3257	ureidoglycine aminohydrolase activity
SG48_RS02645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SG48_RS02650	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SG48_RS02655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SG48_RS02660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SG48_RS02670	COG0549	Belongs to the carbamate kinase family
SG48_RS02675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SG48_RS02680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SG48_RS02690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SG48_RS02700	COG1988	membrane-bound metal-dependent
SG48_RS02705	COG2501	S4 domain
SG48_RS02715	COG3539	Fimbrial protein
SG48_RS02720	COG3121	Chaperone
SG48_RS02725	COG3188	usher protein
SG48_RS02730	COG3539	Fimbrial protein
SG48_RS02735	COG3539	Fimbrial protein
SG48_RS02740	COG2197	response regulator
SG48_RS02750	COG0582	viral genome integration into host DNA
SG48_RS02775	COG2801	Transposase and inactivated derivatives
SG48_RS02785	COG2076	Multidrug Resistance protein
SG48_RS02795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SG48_RS02800	COG1881	PFAM PEBP family protein
SG48_RS02805	COG2207	Transcriptional regulator
SG48_RS02860	COG3772	lysozyme
SG48_RS02880	COG5562	phage envelope protein
SG48_RS02900	COG4220	transposase activity
SG48_RS02910	COG0500	methyltransferase
SG48_RS02920	COG2207	Transcriptional regulator
SG48_RS02925	COG4571	Outer membrane protease
SG48_RS02935	COG2207	Transcriptional regulator
SG48_RS02945	COG4783	chaperone-mediated protein folding
SG48_RS02950	COG1215	transferase activity, transferring glycosyl groups
SG48_RS02955	COG5002	protein histidine kinase activity
SG48_RS02960	COG0745	RESPONSE REGULATOR receiver
SG48_RS02965	COG1538	Outer membrane efflux protein
SG48_RS02970	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SG48_RS02975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SG48_RS02980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SG48_RS02985	COG1113	amino acid transport
SG48_RS02990	COG0668	transmembrane transport
SG48_RS02995	COG0778	Nitroreductase
SG48_RS03000	COG2315	Protein conserved in bacteria
SG48_RS03025	COG3385	transposase activity
SG48_RS03030	COG2977	Belongs to the P-Pant transferase superfamily
SG48_RS03035	COG4771	TonB-dependent receptor
SG48_RS03040	COG2382	esterase
SG48_RS03045	COG3251	PFAM MbtH domain protein
SG48_RS03050	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SG48_RS03050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SG48_RS03055	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
SG48_RS03060	COG1120	ATPase activity
SG48_RS03065	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SG48_RS03070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SG48_RS03080	COG4592	Periplasmic binding protein
SG48_RS03085	COG1169	isochorismate synthase
SG48_RS03090	COG1021	2,3-dihydroxybenzoate-AMP ligase
SG48_RS03095	COG1535	isochorismatase
SG48_RS03095	COG3433	isochorismatase activity
SG48_RS03100	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS03105	COG2050	protein possibly involved in aromatic compounds catabolism
SG48_RS03110	COG1966	Carbon starvation protein
SG48_RS03115	COG2879	small protein
SG48_RS03120	COG0371	Dehydrogenase
SG48_RS03125	COG0436	Aminotransferase
SG48_RS03130	COG1475	DNA binding
SG48_RS03135	COG3969	phosphoadenosine phosphosulfate
SG48_RS03140	COG0583	DNA-binding transcription factor activity
SG48_RS03145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SG48_RS03150	COG0450	alkyl hydroperoxide reductase
SG48_RS03155	COG3634	alkyl hydroperoxide reductase activity
SG48_RS03160	COG0589	response to stress
SG48_RS03165	COG1063	alcohol dehydrogenase
SG48_RS03175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SG48_RS03180	COG3719	Belongs to the RNase T2 family
SG48_RS03185	COG0471	metal ion transport
SG48_RS03200	COG3051	citrate lyase alpha subunit
SG48_RS03205	COG2301	Belongs to the HpcH HpaI aldolase family
SG48_RS03215	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SG48_RS03220	COG3290	protein histidine kinase activity
SG48_RS03225	COG4565	transcriptional regulatory protein
SG48_RS03230	COG3069	C4-dicarboxylate transmembrane transporter activity
SG48_RS03255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SG48_RS03265	COG0583	DNA-binding transcription factor activity
SG48_RS03285	COG1686	Belongs to the peptidase S11 family
SG48_RS03290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SG48_RS03295	COG0772	Belongs to the SEDS family
SG48_RS03300	COG0768	penicillin binding
SG48_RS03310	COG0799	negative regulation of ribosome biogenesis
SG48_RS03315	COG0406	alpha-ribazole phosphatase activity
SG48_RS03325	COG1466	dna polymerase III delta subunit
SG48_RS03340	COG2888	peptidyl-tyrosine sulfation
SG48_RS03345	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SG48_RS03355	COG2214	Heat shock protein DnaJ domain protein
SG48_RS03360	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SG48_RS03370	COG2214	Heat shock protein DnaJ domain protein
SG48_RS03375	COG0443	Heat shock 70 kDa protein
SG48_RS03385	COG1126	abc transporter atp-binding protein
SG48_RS03390	COG0765	amino acid transport
SG48_RS03395	COG0765	amino acid transport
SG48_RS03400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SG48_RS03410	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SG48_RS03415	COG4535	Mg2 and Co2 transporter CorC
SG48_RS03425	COG1702	phosphate starvation-inducible protein PhoH
SG48_RS03435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SG48_RS03475	COG0367	asparagine synthase
SG48_RS03480	COG0647	UMP catabolic process
SG48_RS03485	COG1846	Transcriptional regulator
SG48_RS03485	COG1940	carbohydrate kinase activity
SG48_RS03490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SG48_RS03500	COG1263	PTS System
SG48_RS03500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS03500	COG2190	(PTS) system
SG48_RS03520	COG0735	belongs to the Fur family
SG48_RS03535	COG0716	FMN binding
SG48_RS03545	COG0596	Alpha beta hydrolase
SG48_RS03550	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
SG48_RS03555	COG0033	Phosphoglucomutase
SG48_RS03575	COG0531	amino acid
SG48_RS03580	COG1982	Orn Lys Arg decarboxylase major
SG48_RS03590	COG0745	RESPONSE REGULATOR receiver
SG48_RS03595	COG2205	protein histidine kinase activity
SG48_RS03625	COG3209	COG3209 Rhs family protein
SG48_RS03635	COG3209	COG3209 Rhs family protein
SG48_RS03645	COG5433	transposase activity
SG48_RS03655	COG5433	transposase activity
SG48_RS03660	COG3272	Protein of unknown function (DUF1722)
SG48_RS03665	COG0415	Belongs to the DNA photolyase family
SG48_RS03670	COG3104	oligopeptide transport
SG48_RS03675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SG48_RS03680	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SG48_RS03685	COG1984	allophanate hydrolase subunit 2
SG48_RS03700	COG3180	Ammonia monooxygenase
SG48_RS03705	COG3539	Fimbrial protein
SG48_RS03710	COG3121	Chaperone
SG48_RS03715	COG3188	usher protein
SG48_RS03720	COG3539	Fimbrial protein
SG48_RS03725	COG0372	Belongs to the citrate synthase family
SG48_RS03735	COG2009	succinate dehydrogenase
SG48_RS03740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
SG48_RS03745	COG1053	succinate dehydrogenase
SG48_RS03750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SG48_RS03760	COG0567	Dehydrogenase, E1 component
SG48_RS03765	COG0508	dehydrogenase complex catalyzes the overall conversion of
SG48_RS03775	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SG48_RS03780	COG2188	Transcriptional regulator
SG48_RS03785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS03785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS03785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS03790	COG0383	alpha-mannosidase activity
SG48_RS03800	COG1271	oxidase subunit
SG48_RS03805	COG1294	oxidase, subunit
SG48_RS03810	COG4890	Cyd operon protein YbgT
SG48_RS03815	COG3790	cyd operon protein YbgE
SG48_RS03820	COG0824	Thioesterase
SG48_RS03825	COG0811	peptide transport
SG48_RS03830	COG0848	biopolymer transport protein
SG48_RS03835	COG3064	Membrane
SG48_RS03845	COG2885	chlorophyll binding
SG48_RS03850	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
SG48_RS03895	COG3201	nicotinamide mononucleotide transporter
SG48_RS03900	COG1230	cation diffusion facilitator family transporter
SG48_RS03915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SG48_RS03925	COG2017	converts alpha-aldose to the beta-anomer
SG48_RS03935	COG1085	galactose-1-phosphate uridylyltransferase
SG48_RS03940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SG48_RS03945	COG1119	ATPase activity
SG48_RS03950	COG3585	molybdate ion transport
SG48_RS03950	COG2005	Transcriptional regulator
SG48_RS03960	COG0725	ABC transporter, periplasmic molybdate-binding protein
SG48_RS03965	COG4149	molybdate abc transporter
SG48_RS03970	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SG48_RS03975	COG0561	phosphatase activity
SG48_RS03985	COG0583	DNA-binding transcription factor activity
SG48_RS03990	COG2828	Protein conserved in bacteria
SG48_RS03995	COG0471	metal ion transport
SG48_RS04000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SG48_RS04005	COG4677	pectinesterase activity
SG48_RS04010	COG1881	PFAM PEBP family protein
SG48_RS04015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SG48_RS04030	COG2226	methyltransferase
SG48_RS04035	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SG48_RS04045	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SG48_RS04060	COG0521	Mo-molybdopterin cofactor biosynthetic process
SG48_RS04070	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SG48_RS04075	COG0314	molybdopterin synthase activity
SG48_RS04080	COG0670	Belongs to the BI1 family
SG48_RS04085	COG0670	Belongs to the BI1 family
SG48_RS04090	COG0392	lysyltransferase activity
SG48_RS04095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SG48_RS04100	COG3568	Endonuclease Exonuclease Phosphatase
SG48_RS04110	COG0842	Transport permease protein
SG48_RS04115	COG0842	Transport permease protein
SG48_RS04120	COG1131	(ABC) transporter
SG48_RS04130	COG1309	transcriptional regulator
SG48_RS04135	COG0513	Belongs to the DEAD box helicase family
SG48_RS04140	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
SG48_RS04145	COG1199	ATP-dependent helicase activity
SG48_RS04150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SG48_RS04155	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SG48_RS04165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SG48_RS04175	COG4774	siderophore transport
SG48_RS04190	COG0668	transmembrane transport
SG48_RS04195	COG1126	abc transporter atp-binding protein
SG48_RS04200	COG0765	amino acid transport
SG48_RS04205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SG48_RS04220	COG5006	permease, DMT superfamily
SG48_RS04225	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
SG48_RS04230	COG2194	sulfuric ester hydrolase activity
SG48_RS04240	COG1321	iron dependent repressor
SG48_RS04245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SG48_RS04250	COG1376	ErfK ybiS ycfS ynhG family protein
SG48_RS04255	COG0488	(ABC) transporter
SG48_RS04265	COG0561	phosphatase activity
SG48_RS04270	COG1882	Formate acetyltransferase
SG48_RS04275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SG48_RS04280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SG48_RS04285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SG48_RS04290	COG0303	'Molybdopterin
SG48_RS04295	COG1446	asparaginase
SG48_RS04300	COG4172	Belongs to the ABC transporter superfamily
SG48_RS04305	COG0747	negative chemotaxis
SG48_RS04315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SG48_RS04320	COG2200	EAL domain
SG48_RS04325	COG2199	diguanylate cyclase activity
SG48_RS04340	COG2133	pyrroloquinoline quinone binding
SG48_RS04345	COG0625	glutathione transferase activity
SG48_RS04350	COG1686	Belongs to the peptidase S11 family
SG48_RS04355	COG1349	DNA-binding transcription factor activity
SG48_RS04360	COG0671	phosphoesterase, PA-phosphatase related
SG48_RS04365	COG2814	Major facilitator Superfamily
SG48_RS04375	COG0561	phosphatase activity
SG48_RS04380	COG0738	Major facilitator superfamily
SG48_RS04385	COG3226	Transcriptional regulator
SG48_RS04400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SG48_RS04410	COG0778	Nitroreductase
SG48_RS04430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SG48_RS04435	COG3842	ATPase activity
SG48_RS04440	COG1176	ABC-type spermidine putrescine transport system, permease component I
SG48_RS04445	COG1177	transmembrane transport
SG48_RS04460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SG48_RS04465	COG4160	amino acid transport
SG48_RS04470	COG4215	(ABC) transporter
SG48_RS04475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SG48_RS04480	COG1126	abc transporter atp-binding protein
SG48_RS04495	COG3023	N-Acetylmuramoyl-L-alanine amidase
SG48_RS04500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SG48_RS04505	COG0702	epimerase
SG48_RS04510	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
SG48_RS04515	COG0028	Belongs to the TPP enzyme family
SG48_RS04520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SG48_RS04530	COG2431	L-lysine efflux transmembrane transporter activity
SG48_RS04545	COG3593	DNA synthesis involved in DNA repair
SG48_RS04550	COG2990	Protein conserved in bacteria
SG48_RS04555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SG48_RS04560	COG1136	(ABC) transporter
SG48_RS04560	COG0577	efflux transmembrane transporter activity
SG48_RS04565	COG1278	Cold shock
SG48_RS04575	COG0542	response to heat
SG48_RS04595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SG48_RS04600	COG4988	ABC transporter
SG48_RS04605	COG0492	ferredoxin-NADP+ reductase activity
SG48_RS04610	COG1522	sequence-specific DNA binding
SG48_RS04615	COG1178	ABC-type Fe3 transport system permease component
SG48_RS04615	COG1674	ftsk spoiiie
SG48_RS04625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SG48_RS04635	COG0243	molybdopterin cofactor binding
SG48_RS04640	COG0437	4 iron, 4 sulfur cluster binding
SG48_RS04645	COG3302	dmso reductase anchor subunit
SG48_RS04650	COG1335	isochorismatase
SG48_RS04660	COG0531	amino acid
SG48_RS04665	COG0583	DNA-binding transcription factor activity
SG48_RS04670	COG2249	NAD(P)H dehydrogenase (quinone) activity
SG48_RS04675	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SG48_RS04680	COG1882	Formate acetyltransferase
SG48_RS04685	COG2116	formate transmembrane transporter activity
SG48_RS04690	COG1944	ATP diphosphatase activity
SG48_RS04695	COG2323	membrane
SG48_RS04710	COG0501	Belongs to the peptidase M48B family
SG48_RS04720	COG0539	negative regulation of cytoplasmic translation
SG48_RS04730	COG2333	competence protein COMEC
SG48_RS04730	COG0658	competence protein
SG48_RS04735	COG1132	(ABC) transporter
SG48_RS04740	COG1663	tetraacyldisaccharide 4'-kinase activity
SG48_RS04745	COG3214	Protein conserved in bacteria
SG48_RS04760	COG3173	Aminoglycoside phosphotransferase
SG48_RS04765	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SG48_RS04770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SG48_RS04780	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
SG48_RS04790	COG2989	Protein conserved in bacteria
SG48_RS04795	COG3108	Peptidase M15
SG48_RS04800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SG48_RS04805	COG1448	Aminotransferase
SG48_RS04830	COG0308	aminopeptidase N
SG48_RS04835	COG1116	anion transmembrane transporter activity
SG48_RS04840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SG48_RS04850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SG48_RS04855	COG0431	NADPH-dependent FMN reductase
SG48_RS04860	COG3539	Fimbrial protein
SG48_RS04865	COG3121	Chaperone
SG48_RS04870	COG3188	usher protein
SG48_RS04875	COG3539	Fimbrial protein
SG48_RS04880	COG3539	Fimbrial protein
SG48_RS04885	COG3539	Fimbrial protein
SG48_RS04890	COG3121	Chaperone
SG48_RS04905	COG3217	Mosc domain protein beta barrel domain protein
SG48_RS04905	COG0633	Ferredoxin
SG48_RS04915	COG0488	(ABC) transporter
SG48_RS04920	COG2995	paraquat-inducible protein a
SG48_RS04925	COG3008	intermembrane lipid transfer
SG48_RS04925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SG48_RS04930	COG3009	Protein conserved in bacteria
SG48_RS04935	COG3130	regulation of translation
SG48_RS04945	COG1067	ATP-dependent peptidase activity
SG48_RS04955	COG2885	chlorophyll binding
SG48_RS04955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
SG48_RS04970	COG3070	regulator of competence-specific genes
SG48_RS04975	COG1289	transmembrane transporter activity
SG48_RS04980	COG3304	Inner membrane component domain
SG48_RS04985	COG0210	DNA helicase
SG48_RS05005	COG1832	CoA-binding protein
SG48_RS05020	COG1254	Belongs to the acylphosphatase family
SG48_RS05025	COG2920	part of a sulfur-relay system
SG48_RS05030	COG0670	Belongs to the BI1 family
SG48_RS05040	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SG48_RS05045	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SG48_RS05050	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
SG48_RS05055	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SG48_RS05060	COG1999	signal sequence binding
SG48_RS05065	COG1773	rubredoxin
SG48_RS05070	COG1271	oxidase subunit
SG48_RS05075	COG1294	oxidase, subunit
SG48_RS05090	COG3206	protein involved in exopolysaccharide biosynthesis
SG48_RS05090	COG0489	protein tyrosine kinase activity
SG48_RS05095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SG48_RS05100	COG1596	polysaccharide export
SG48_RS05105	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SG48_RS05130	COG1662	PFAM IS1 transposase
SG48_RS05135	COG1278	Cold shock
SG48_RS05140	COG1278	Cold shock
SG48_RS05155	COG0348	domain, Protein
SG48_RS05160	COG2205	protein histidine kinase activity
SG48_RS05160	COG2198	Histidine kinase
SG48_RS05160	COG0784	Response regulator, receiver
SG48_RS05165	COG1879	ABC-type sugar transport system periplasmic component
SG48_RS05170	COG0745	RESPONSE REGULATOR receiver
SG48_RS05175	COG3005	denitrification pathway
SG48_RS05180	COG0243	molybdopterin cofactor binding
SG48_RS05185	COG3381	protein complex oligomerization
SG48_RS05225	COG3729	General stress protein
SG48_RS05230	COG2233	PERMEase
SG48_RS05265	COG1309	transcriptional regulator
SG48_RS05270	COG0506	proline dehydrogenase activity
SG48_RS05270	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SG48_RS05270	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SG48_RS05280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SG48_RS05295	COG2822	iron ion transport
SG48_RS05300	COG2837	iron assimilation
SG48_RS05310	COG1702	phosphate starvation-inducible protein PhoH
SG48_RS05315	COG3658	cytochrome
SG48_RS05320	COG1215	transferase activity, transferring glycosyl groups
SG48_RS05325	COG1649	PFAM Uncharacterised BCR, COG1649
SG48_RS05325	COG0726	polysaccharide deacetylase
SG48_RS05330	COG0457	Tetratricopeptide repeat
SG48_RS05335	COG3706	GGDEF domain
SG48_RS05340	COG2801	Transposase and inactivated derivatives
SG48_RS05380	COG3381	protein complex oligomerization
SG48_RS05390	COG1462	curli production assembly transport component CsgG
SG48_RS05405	COG2197	response regulator
SG48_RS05435	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SG48_RS05440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SG48_RS05465	COG2943	transferase activity, transferring hexosyl groups
SG48_RS05470	COG5645	(Lipo)protein
SG48_RS05490	COG1560	Kdo2-lipid A biosynthetic process
SG48_RS05500	COG2353	YceI-like domain
SG48_RS05505	COG3038	cytochrome b561
SG48_RS05540	COG2999	glutathione oxidoreductase activity
SG48_RS05550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SG48_RS05560	COG0673	inositol 2-dehydrogenase activity
SG48_RS05565	COG0728	peptidoglycan biosynthetic process
SG48_RS05570	COG3418	PFAM FlgN family protein
SG48_RS05575	COG2747	anti-sigma28 factor FlgM
SG48_RS05580	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
SG48_RS05585	COG1815	bacterial-type flagellum-dependent cell motility
SG48_RS05590	COG1558	bacterial-type flagellum-dependent cell motility
SG48_RS05595	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SG48_RS05600	COG1749	Flagellar hook protein flgE
SG48_RS05605	COG4787	bacterial-type flagellum-dependent cell motility
SG48_RS05610	COG4786	Flagellar basal body rod
SG48_RS05625	COG3951	Flagellar rod assembly protein muramidase FlgJ
SG48_RS05625	COG1705	Flagellar rod assembly protein muramidase FlgJ
SG48_RS05630	COG1256	bacterial-type flagellum assembly
SG48_RS05635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SG48_RS05640	COG1530	ribonuclease E activity
SG48_RS05650	COG0564	pseudouridine synthase activity
SG48_RS05655	COG0424	maF-like protein
SG48_RS05660	COG1399	metal-binding, possibly nucleic acid-binding protein
SG48_RS05680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SG48_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS05695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SG48_RS05700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SG48_RS05705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SG48_RS05715	COG0470	DNA polymerase III
SG48_RS05720	COG0084	hydrolase, TatD family'
SG48_RS05725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS05725	COG1263	PTS System
SG48_RS05730	COG4773	Receptor
SG48_RS05735	COG0537	adenosine 5'-monophosphoramidase activity
SG48_RS05740	COG5633	Lipoprotein
SG48_RS05745	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
SG48_RS05765	COG1252	NADH dehydrogenase
SG48_RS05770	COG3134	Outer membrane lipoprotein
SG48_RS05775	COG1309	transcriptional regulator
SG48_RS05785	COG1388	LysM domain
SG48_RS05785	COG1376	ErfK ybiS ycfS ynhG family protein
SG48_RS05790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SG48_RS05795	COG4763	Acyl-transferase
SG48_RS05800	COG4591	ABC-type transport system involved in lipoprotein release permease component
SG48_RS05805	COG1136	(ABC) transporter
SG48_RS05810	COG4591	ABC-type transport system involved in lipoprotein release permease component
SG48_RS05820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SG48_RS05825	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
SG48_RS05835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SG48_RS05840	COG1177	transmembrane transport
SG48_RS05850	COG3842	ATPase activity
SG48_RS05865	COG2850	peptidyl-arginine hydroxylation
SG48_RS05870	COG2205	protein histidine kinase activity
SG48_RS05875	COG0745	RESPONSE REGULATOR receiver
SG48_RS05880	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SG48_RS05900	COG1187	pseudouridine synthase activity
SG48_RS05905	COG0538	isocitrate dehydrogenase activity
SG48_RS05910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SG48_RS05925	COG0582	viral genome integration into host DNA
SG48_RS05940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SG48_RS05945	COG4197	protein conserved in bacteria, prophage-related
SG48_RS05960	COG4626	Terminase
SG48_RS05960	COG1802	Transcriptional regulator
SG48_RS05970	COG4695	Portal protein
SG48_RS05975	COG3299	homolog of phage Mu protein gp47
SG48_RS05980	COG3778	Protein conserved in bacteria
SG48_RS05995	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SG48_RS06005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SG48_RS06010	COG1403	HNH endonuclease
SG48_RS06025	COG5562	phage envelope protein
SG48_RS06030	COG0789	Transcriptional regulator
SG48_RS06035	COG2200	EAL domain
SG48_RS06060	COG2200	EAL domain
SG48_RS06110	COG2894	cell division
SG48_RS06140	COG0179	Fumarylacetoacetate (FAA) hydrolase
SG48_RS06155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SG48_RS06160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SG48_RS06165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SG48_RS06180	COG2719	SpoVR family
SG48_RS06190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SG48_RS06200	COG1619	proteins homologs of microcin C7 resistance protein MccF
SG48_RS06210	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
SG48_RS06215	COG2261	transglycosylase associated protein
SG48_RS06230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS06230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SG48_RS06230	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SG48_RS06235	COG1461	Dihydroxyacetone kinase
SG48_RS06240	COG2376	Dihydroxyacetone kinase
SG48_RS06245	COG3284	Transcriptional regulator
SG48_RS06250	COG3468	outer membrane autotransporter barrel domain protein
SG48_RS06260	COG0012	GTP binding
SG48_RS06275	COG0659	secondary active sulfate transmembrane transporter activity
SG48_RS06280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SG48_RS06305	COG2890	protein-(glutamine-N5) methyltransferase activity
SG48_RS06310	COG3094	Invasion gene expression up-regulator, SirB
SG48_RS06315	COG2912	Transglutaminase-like superfamily
SG48_RS06340	COG0387	Pfam Sodium calcium exchanger
SG48_RS06345	COG4572	Cation transport regulator
SG48_RS06350	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
SG48_RS06355	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
SG48_RS06360	COG4932	domain protein
SG48_RS06365	COG2197	response regulator
SG48_RS06370	COG3850	Histidine kinase
SG48_RS06380	COG2223	nitrite transmembrane transporter activity
SG48_RS06385	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SG48_RS06390	COG1140	nitrate reductase beta subunit
SG48_RS06395	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SG48_RS06400	COG2181	nitrate reductase activity
SG48_RS06420	COG0788	formyltetrahydrofolate deformylase activity
SG48_RS06430	COG1752	Esterase of the alpha-beta hydrolase superfamily
SG48_RS06435	COG0745	RESPONSE REGULATOR receiver
SG48_RS06440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SG48_RS06450	COG1435	thymidine kinase activity
SG48_RS06465	COG1012	belongs to the aldehyde dehydrogenase family
SG48_RS06465	COG1454	alcohol dehydrogenase
SG48_RS06470	COG2095	MarC family integral membrane protein
SG48_RS06475	COG4166	transmembrane transport
SG48_RS06480	COG0601	transmembrane transport
SG48_RS06485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SG48_RS06490	COG0444	Belongs to the ABC transporter superfamily
SG48_RS06495	COG4608	Belongs to the ABC transporter superfamily
SG48_RS06515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SG48_RS06520	COG2350	Protein conserved in bacteria
SG48_RS06525	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
SG48_RS06530	COG1607	acyl-coa hydrolase
SG48_RS06545	COG3047	cAMP biosynthetic process
SG48_RS06550	COG3685	Protein conserved in bacteria
SG48_RS06555	COG3685	Protein conserved in bacteria
SG48_RS06560	COG3729	General stress protein
SG48_RS06575	COG0134	indole-3-glycerol-phosphate synthase activity
SG48_RS06575	COG0135	phosphoribosylanthranilate isomerase activity
SG48_RS06580	COG0512	Glutamine amidotransferase of anthranilate synthase
SG48_RS06580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SG48_RS06585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SG48_RS06590	COG0613	PHP domain protein
SG48_RS06595	COG0009	L-threonylcarbamoyladenylate synthase
SG48_RS06600	COG4907	membrane protein (DUF2207)
SG48_RS06605	COG1187	pseudouridine synthase activity
SG48_RS06610	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SG48_RS06615	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS06625	COG0616	signal peptide processing
SG48_RS06640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SG48_RS06645	COG0583	DNA-binding transcription factor activity
SG48_RS06665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SG48_RS06675	COG0671	phosphoesterase, PA-phosphatase related
SG48_RS06680	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
SG48_RS06685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
SG48_RS06695	COG0023	Translation Initiation Factor
SG48_RS06705	COG1349	DNA-binding transcription factor activity
SG48_RS06715	COG5001	Diguanylate cyclase
SG48_RS06730	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SG48_RS06730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SG48_RS06735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SG48_RS06740	COG2852	Protein conserved in bacteria
SG48_RS06745	COG4172	Belongs to the ABC transporter superfamily
SG48_RS06750	COG4172	Belongs to the ABC transporter superfamily
SG48_RS06755	COG4171	peptide transport system, permease
SG48_RS06760	COG4168	peptide transport system, permease
SG48_RS06765	COG4166	transmembrane transport
SG48_RS06780	COG0531	amino acid
SG48_RS06785	COG0174	glutamine synthetase
SG48_RS06790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SG48_RS06795	COG1396	sequence-specific DNA binding
SG48_RS06795	COG1917	Cupin 2, conserved barrel domain protein
SG48_RS06800	COG1012	belongs to the aldehyde dehydrogenase family
SG48_RS06805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SG48_RS06810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SG48_RS06815	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SG48_RS06820	COG1842	Phage shock protein A
SG48_RS06830	COG1983	PspC domain protein
SG48_RS06840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SG48_RS06845	COG0366	Alpha amylase catalytic
SG48_RS06850	COG1653	transport
SG48_RS06855	COG1175	transmembrane transport
SG48_RS06860	COG0395	ABC-type sugar transport system, permease component
SG48_RS06865	COG1063	alcohol dehydrogenase
SG48_RS06870	COG1082	Xylose isomerase domain protein TIM barrel
SG48_RS06875	COG0673	inositol 2-dehydrogenase activity
SG48_RS06880	COG1554	hydrolase, family 65, central catalytic
SG48_RS06885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SG48_RS06900	COG1609	Transcriptional regulator
SG48_RS06905	COG3106	COG3106 Predicted ATPase
SG48_RS06915	COG3283	Transcriptional regulator of aromatic amino acids metabolism
SG48_RS06920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SG48_RS06925	COG4948	Mandelate Racemase Muconate Lactonizing
SG48_RS06930	COG2866	Carboxypeptidase
SG48_RS06935	COG0702	epimerase
SG48_RS06940	COG1073	alpha beta
SG48_RS06945	COG0583	DNA-binding transcription factor activity
SG48_RS06955	COG4166	transmembrane transport
SG48_RS06960	COG0668	transmembrane transport
SG48_RS06970	COG3182	Iron-regulated membrane protein
SG48_RS06975	COG0589	response to stress
SG48_RS06980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SG48_RS06985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SG48_RS06990	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SG48_RS07000	COG1473	amidohydrolase
SG48_RS07005	COG1473	amidohydrolase
SG48_RS07010	COG0583	DNA-binding transcription factor activity
SG48_RS07020	COG2840	Smr protein MutS2
SG48_RS07025	COG3706	GGDEF domain
SG48_RS07040	COG0513	Belongs to the DEAD box helicase family
SG48_RS07050	COG0582	viral genome integration into host DNA
SG48_RS07070	COG3723	Recombinational DNA repair protein, rece pathway
SG48_RS07075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SG48_RS07105	COG4197	protein conserved in bacteria, prophage-related
SG48_RS07115	COG3756	Protein conserved in bacteria
SG48_RS07120	COG1484	DNA-dependent DNA replication
SG48_RS07125	COG1846	Transcriptional regulator
SG48_RS07135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SG48_RS07140	COG1475	DNA binding
SG48_RS07155	COG1196	nuclear chromosome segregation
SG48_RS07165	COG3039	Transposase
SG48_RS07185	COG5301	cellulose 1,4-beta-cellobiosidase activity
SG48_RS07190	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SG48_RS07195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SG48_RS07205	COG0589	response to stress
SG48_RS07210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SG48_RS07215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SG48_RS07215	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SG48_RS07215	COG1013	pyruvate-flavodoxin oxidoreductase activity
SG48_RS07215	COG0674	pyruvate-flavodoxin oxidoreductase activity
SG48_RS07220	COG3042	response to heat
SG48_RS07225	COG3187	Heat shock protein
SG48_RS07230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SG48_RS07235	COG2911	Protein conserved in bacteria
SG48_RS07245	COG3784	Protein of unknown function (DUF1318)
SG48_RS07250	COG2207	Transcriptional regulator
SG48_RS07255	COG1012	belongs to the aldehyde dehydrogenase family
SG48_RS07260	COG3733	amine oxidase
SG48_RS07265	COG1012	belongs to the aldehyde dehydrogenase family
SG48_RS07265	COG2030	dehydratase
SG48_RS07270	COG3396	Phenylacetate-CoA oxygenase
SG48_RS07275	COG3460	Phenylacetate-CoA oxygenase
SG48_RS07280	COG3396	Phenylacetate-CoA oxygenase
SG48_RS07285	COG2151	metal-sulfur cluster biosynthetic enzyme
SG48_RS07290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SG48_RS07295	COG1024	Enoyl-CoA hydratase
SG48_RS07300	COG1024	Enoyl-CoA hydratase
SG48_RS07305	COG1250	3-hydroxyacyl-CoA dehydrogenase
SG48_RS07310	COG2050	protein possibly involved in aromatic compounds catabolism
SG48_RS07315	COG0183	Belongs to the thiolase family
SG48_RS07320	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
SG48_RS07325	COG3327	negative regulation of DNA-templated transcription, initiation
SG48_RS07330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SG48_RS07350	COG2826	transposase and inactivated derivatives, IS30 family
SG48_RS07360	COG0667	Aldo Keto reductase
SG48_RS07370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SG48_RS07375	COG4589	Belongs to the CDS family
SG48_RS07380	COG2267	carboxylic ester hydrolase activity
SG48_RS07385	COG0671	phosphoesterase, PA-phosphatase related
SG48_RS07385	COG2453	phosphatase
SG48_RS07395	COG1643	Atp-dependent helicase
SG48_RS07400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SG48_RS07405	COG1012	belongs to the aldehyde dehydrogenase family
SG48_RS07410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SG48_RS07415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SG48_RS07420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SG48_RS07425	COG3038	cytochrome b561
SG48_RS07440	COG0840	transmembrane signaling receptor activity
SG48_RS07445	COG0583	DNA-binding transcription factor activity
SG48_RS07450	COG5383	Protein conserved in bacteria
SG48_RS07465	COG2841	Protein conserved in bacteria
SG48_RS07470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SG48_RS07475	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SG48_RS07480	COG1275	C4-dicarboxylate transporter malic acid transport protein
SG48_RS07485	COG0500	methyltransferase
SG48_RS07505	COG0675	Transposase, IS605 OrfB family
SG48_RS07510	COG3135	benzoate transporter
SG48_RS07515	COG1396	sequence-specific DNA binding
SG48_RS07520	COG0826	peptidase U32
SG48_RS07530	COG1724	mRNA binding
SG48_RS07535	COG1598	PFAM Uncharacterised protein family UPF0150
SG48_RS07540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SG48_RS07545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SG48_RS07550	COG3842	ATPase activity
SG48_RS07555	COG1176	ABC-type spermidine putrescine transport system, permease component I
SG48_RS07560	COG1177	transmembrane transport
SG48_RS07585	COG3238	Protein conserved in bacteria
SG48_RS07590	COG1247	-acetyltransferase
SG48_RS07595	COG2130	NADP-dependent
SG48_RS07600	COG1802	Transcriptional regulator
SG48_RS07605	COG4772	TonB-dependent receptor
SG48_RS07610	COG3391	amine dehydrogenase activity
SG48_RS07615	COG1113	amino acid transport
SG48_RS07620	COG0625	glutathione transferase activity
SG48_RS07630	COG3209	COG3209 Rhs family protein
SG48_RS07640	COG5433	transposase activity
SG48_RS07645	COG5433	transposase activity
SG48_RS07655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SG48_RS07660	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SG48_RS07665	COG0384	phenazine biosynthesis protein PhzF
SG48_RS07670	COG2181	nitrate reductase activity
SG48_RS07675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SG48_RS07680	COG1140	nitrate reductase beta subunit
SG48_RS07685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SG48_RS07690	COG2223	nitrite transmembrane transporter activity
SG48_RS07700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SG48_RS07705	COG0697	spore germination
SG48_RS07710	COG3383	formate dehydrogenase (NAD+) activity
SG48_RS07710	COG0243	molybdopterin cofactor binding
SG48_RS07715	COG0243	molybdopterin cofactor binding
SG48_RS07715	COG3383	formate dehydrogenase (NAD+) activity
SG48_RS07720	COG0437	4 iron, 4 sulfur cluster binding
SG48_RS07725	COG2864	formate dehydrogenase
SG48_RS07730	COG3093	addiction module antidote protein HigA
SG48_RS07735	COG1064	alcohol dehydrogenase
SG48_RS07755	COG1764	response to oxidative stress
SG48_RS07760	COG4608	Belongs to the ABC transporter superfamily
SG48_RS07765	COG0444	Belongs to the ABC transporter superfamily
SG48_RS07770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SG48_RS07775	COG0601	transmembrane transport
SG48_RS07780	COG0747	negative chemotaxis
SG48_RS07785	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SG48_RS07790	COG2202	Pas domain
SG48_RS07790	COG2199	diguanylate cyclase activity
SG48_RS07790	COG2200	EAL domain
SG48_RS07795	COG3706	GGDEF domain
SG48_RS07800	COG1649	PFAM Uncharacterised BCR, COG1649
SG48_RS07805	COG0531	amino acid
SG48_RS07810	COG0076	glutamate decarboxylase activity
SG48_RS07820	COG0612	Peptidase, M16
SG48_RS07825	COG4771	TonB-dependent receptor
SG48_RS07830	COG4178	(ABC) transporter
SG48_RS07835	COG0641	radical SAM
SG48_RS07840	COG3119	arylsulfatase activity
SG48_RS07845	COG2207	Transcriptional regulator
SG48_RS07855	COG0243	molybdopterin cofactor binding
SG48_RS07860	COG3539	Fimbrial protein
SG48_RS07865	COG3539	Fimbrial protein
SG48_RS07870	COG3539	Fimbrial protein
SG48_RS07875	COG3188	usher protein
SG48_RS07880	COG4977	sequence-specific DNA binding
SG48_RS07885	COG3550	peptidyl-serine autophosphorylation
SG48_RS07890	COG1396	sequence-specific DNA binding
SG48_RS07900	COG2911	Protein conserved in bacteria
SG48_RS07900	COG3210	domain, Protein
SG48_RS07950	COG3781	membrane
SG48_RS07965	COG2199	diguanylate cyclase activity
SG48_RS07975	COG2066	Belongs to the glutaminase family
SG48_RS07980	COG1012	belongs to the aldehyde dehydrogenase family
SG48_RS07985	COG0583	DNA-binding transcription factor activity
SG48_RS08005	COG1846	Transcriptional regulator
SG48_RS08010	COG4977	sequence-specific DNA binding
SG48_RS08020	COG0697	spore germination
SG48_RS08025	COG2814	Major facilitator Superfamily
SG48_RS08035	COG3706	GGDEF domain
SG48_RS08040	COG3111	PFAM Bacterial OB fold (BOF) protein
SG48_RS08045	COG1546	Belongs to the CinA family
SG48_RS08050	COG0339	signal peptide processing
SG48_RS08055	COG4221	oxidoreductase activity
SG48_RS08060	COG1802	Transcriptional regulator
SG48_RS08070	COG0246	Mannitol dehydrogenase
SG48_RS08075	COG0477	Major facilitator Superfamily
SG48_RS08085	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SG48_RS08090	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SG48_RS08095	COG5301	cellulose 1,4-beta-cellobiosidase activity
SG48_RS08100	COG4220	transposase activity
SG48_RS08110	COG5562	phage envelope protein
SG48_RS08125	COG1278	Cold shock
SG48_RS08135	COG3772	lysozyme
SG48_RS08150	COG1278	Cold shock
SG48_RS08155	COG1278	Cold shock
SG48_RS08160	COG0484	heat shock protein binding
SG48_RS08165	COG1403	HNH endonuclease
SG48_RS08185	COG2026	Addiction module toxin, RelE StbE family
SG48_RS08190	COG3077	Addiction module antitoxin, RelB DinJ family
SG48_RS08210	COG1396	sequence-specific DNA binding
SG48_RS08250	COG0582	viral genome integration into host DNA
SG48_RS08255	COG1063	alcohol dehydrogenase
SG48_RS08260	COG4948	Mandelate Racemase Muconate Lactonizing
SG48_RS08275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SG48_RS08290	COG0243	molybdopterin cofactor binding
SG48_RS08295	COG0243	molybdopterin cofactor binding
SG48_RS08300	COG0437	4 iron, 4 sulfur cluster binding
SG48_RS08305	COG3302	dmso reductase anchor subunit
SG48_RS08310	COG3381	protein complex oligomerization
SG48_RS08320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SG48_RS08325	COG1940	carbohydrate kinase activity
SG48_RS08330	COG0583	DNA-binding transcription factor activity
SG48_RS08335	COG2814	Major facilitator Superfamily
SG48_RS08350	COG3591	Belongs to the peptidase S1B family
SG48_RS08365	COG0628	permease
SG48_RS08370	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SG48_RS08375	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SG48_RS08385	COG0531	amino acid
SG48_RS08395	COG3136	membrane protein required for alginate biosynthesis
SG48_RS08400	COG0745	RESPONSE REGULATOR receiver
SG48_RS08405	COG2205	protein histidine kinase activity
SG48_RS08415	COG0114	fumarate hydratase activity
SG48_RS08420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SG48_RS08420	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SG48_RS08425	COG1482	cell wall glycoprotein biosynthetic process
SG48_RS08430	COG5339	Protein conserved in bacteria
SG48_RS08440	COG2211	Major facilitator Superfamily
SG48_RS08445	COG3250	beta-galactosidase activity
SG48_RS08450	COG1309	transcriptional regulator
SG48_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS08460	COG1609	Transcriptional regulator
SG48_RS08465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS08465	COG1263	PTS System
SG48_RS08470	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SG48_RS08480	COG0673	inositol 2-dehydrogenase activity
SG48_RS08520	COG4659	FMN binding
SG48_RS08530	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SG48_RS08540	COG3104	oligopeptide transport
SG48_RS08545	COG0625	glutathione transferase activity
SG48_RS08550	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
SG48_RS08565	COG3895	Periplasmic Protein
SG48_RS08575	COG3133	Outer membrane lipoprotein
SG48_RS08590	COG1566	PFAM secretion protein HlyD family protein
SG48_RS08595	COG1289	transmembrane transporter activity
SG48_RS08600	COG2032	superoxide dismutase activity
SG48_RS08605	COG4989	oxidoreductase activity
SG48_RS08610	COG3313	Fe-S protein
SG48_RS08615	COG1309	transcriptional regulator
SG48_RS08620	COG1902	pentaerythritol trinitrate reductase activity
SG48_RS08625	COG0346	lactoylglutathione lyase activity
SG48_RS08630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SG48_RS08635	COG1201	RNA secondary structure unwinding
SG48_RS08640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SG48_RS08645	COG0791	NLP P60 protein
SG48_RS08650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SG48_RS08655	COG2814	Major facilitator Superfamily
SG48_RS08670	COG0583	DNA-binding transcription factor activity
SG48_RS08675	COG2814	Major facilitator Superfamily
SG48_RS08680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SG48_RS08685	COG0307	riboflavin synthase, alpha
SG48_RS08695	COG3468	outer membrane autotransporter barrel domain protein
SG48_RS08715	COG4529	Protein conserved in bacteria
SG48_RS08725	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
SG48_RS08730	COG0437	4 iron, 4 sulfur cluster binding
SG48_RS08740	COG2414	aldehyde ferredoxin oxidoreductase
SG48_RS08745	COG0437	4 iron, 4 sulfur cluster binding
SG48_RS08755	COG0469	pyruvate kinase activity
SG48_RS08760	COG4238	major outer membrane lipoprotein
SG48_RS08765	COG1376	ErfK ybiS ycfS ynhG family protein
SG48_RS08780	COG0719	Fe-S assembly protein
SG48_RS08785	COG0396	ATPase activity
SG48_RS08790	COG0719	Fe-S assembly protein
SG48_RS08795	COG0316	Belongs to the HesB IscA family
SG48_RS08805	COG2050	protein possibly involved in aromatic compounds catabolism
SG48_RS08810	COG0247	lactate metabolic process
SG48_RS08810	COG0277	FAD linked oxidase domain protein
SG48_RS08815	COG0628	permease
SG48_RS08825	COG0738	Major facilitator superfamily
SG48_RS08830	COG2271	Major facilitator Superfamily
SG48_RS08845	COG4670	ketone body catabolic process
SG48_RS08850	COG1960	acyl-CoA dehydrogenase activity
SG48_RS08855	COG2207	Transcriptional regulator
SG48_RS08855	COG1917	Cupin 2, conserved barrel domain protein
SG48_RS08865	COG2086	electron transfer activity
SG48_RS08870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SG48_RS08875	COG0644	oxidoreductase
SG48_RS08880	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SG48_RS08885	COG0318	PFAM AMP-dependent synthetase and ligase
SG48_RS08890	COG0574	Belongs to the PEP-utilizing enzyme family
SG48_RS08890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SG48_RS08905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SG48_RS08910	COG4256	Hemin uptake protein
SG48_RS08920	COG2200	EAL domain
SG48_RS08925	COG0791	NLP P60 protein
SG48_RS08935	COG0386	Belongs to the glutathione peroxidase family
SG48_RS08950	COG0072	phenylalanine-tRNA ligase activity
SG48_RS08950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SG48_RS08995	COG3137	Salt-induced outer membrane protein
SG48_RS09000	COG1105	Belongs to the carbohydrate kinase PfkB family
SG48_RS09010	COG3001	Fructosamine kinase
SG48_RS09020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SG48_RS09025	COG1988	membrane-bound metal-dependent
SG48_RS09030	COG1823	symporter activity
SG48_RS09045	COG0753	catalase activity
SG48_RS09055	COG1486	melibiose metabolic process
SG48_RS09060	COG2169	Transcriptional regulator
SG48_RS09060	COG1917	Cupin 2, conserved barrel domain protein
SG48_RS09065	COG1447	Phosphotransferase system cellobiose-specific component IIA
SG48_RS09070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SG48_RS09075	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SG48_RS09080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SG48_RS09095	COG0322	excinuclease ABC activity
SG48_RS09105	COG3678	ATP-independent chaperone mediated protein folding
SG48_RS09135	COG0708	Exodeoxyribonuclease III
SG48_RS09140	COG0398	Pfam SNARE associated Golgi protein
SG48_RS09150	COG0398	Pfam SNARE associated Golgi protein
SG48_RS09155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SG48_RS09160	COG4134	Bacterial extracellular solute-binding protein
SG48_RS09165	COG4135	transport system, permease component
SG48_RS09170	COG4136	ATPase activity
SG48_RS09175	COG2897	thiosulfate sulfurtransferase activity
SG48_RS09180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SG48_RS09185	COG0494	nUDIX hydrolase
SG48_RS09195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SG48_RS09205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SG48_RS09220	COG0778	Nitroreductase
SG48_RS09230	COG0616	signal peptide processing
SG48_RS09235	COG0252	asparaginase activity
SG48_RS09240	COG1335	isochorismatase
SG48_RS09245	COG2814	Major facilitator Superfamily
SG48_RS09250	COG1349	DNA-binding transcription factor activity
SG48_RS09255	COG0667	Aldo Keto reductase
SG48_RS09260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SG48_RS09265	COG0191	fructose-bisphosphate aldolase activity
SG48_RS09270	COG1063	alcohol dehydrogenase
SG48_RS09275	COG2271	Major facilitator Superfamily
SG48_RS09280	COG1063	alcohol dehydrogenase
SG48_RS09285	COG3139	Protein of unknown function (DUF1315)
SG48_RS09295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SG48_RS09300	COG0676	glucose-6-phosphate 1-epimerase activity
SG48_RS09305	COG0656	L-ascorbic acid biosynthetic process
SG48_RS09310	COG3713	MltA-interacting MipA family protein
SG48_RS09315	COG2766	serine protein kinase
SG48_RS09325	COG2199	diguanylate cyclase activity
SG48_RS09330	COG2199	diguanylate cyclase activity
SG48_RS09335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SG48_RS09350	COG2207	Transcriptional regulator
SG48_RS09355	COG2807	transmembrane transport
SG48_RS09360	COG3189	MarR family transcriptional regulator
SG48_RS09365	COG3042	response to heat
SG48_RS09370	COG2199	diguanylate cyclase activity
SG48_RS09370	COG2203	Gaf domain
SG48_RS09380	COG2261	transglycosylase associated protein
SG48_RS09390	COG3615	Tellurite resistance protein tehB
SG48_RS09400	COG0583	DNA-binding transcription factor activity
SG48_RS09405	COG0473	3-isopropylmalate dehydrogenase activity
SG48_RS09410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SG48_RS09415	COG4638	Rieske (2fe-2S)
SG48_RS09420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SG48_RS09425	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SG48_RS09430	COG0318	PFAM AMP-dependent synthetase and ligase
SG48_RS09435	COG3065	identical protein binding
SG48_RS09440	COG1214	PFAM Peptidase M22, glycoprotease
SG48_RS09445	COG1199	ATP-dependent helicase activity
SG48_RS09450	COG0251	oxidation-reduction process
SG48_RS09465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SG48_RS09475	COG1760	l-serine dehydratase
SG48_RS09480	COG2200	EAL domain
SG48_RS09485	COG1253	flavin adenine dinucleotide binding
SG48_RS09495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS09495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS09500	COG3715	PTS system
SG48_RS09505	COG3716	PTS system mannose fructose sorbose family IID component
SG48_RS09525	COG2226	methyltransferase
SG48_RS09560	COG1414	Transcriptional regulator
SG48_RS09565	COG2814	Major facilitator Superfamily
SG48_RS09575	COG0793	Belongs to the peptidase S41A family
SG48_RS09585	COG1956	GAF domain-containing protein
SG48_RS09590	COG2995	paraquat-inducible protein a
SG48_RS09595	COG3008	intermembrane lipid transfer
SG48_RS09615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SG48_RS09630	COG1276	copper resistance
SG48_RS09635	COG2372	response to copper ion
SG48_RS09645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SG48_RS09650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SG48_RS09655	COG1770	oligopeptidase
SG48_RS09660	COG2979	Protein of unknown function (DUF533)
SG48_RS09675	COG3141	response to X-ray
SG48_RS09685	COG0800	Aldolase
SG48_RS09690	COG0129	dihydroxy-acid dehydratase activity
SG48_RS09695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SG48_RS09705	COG1737	Transcriptional regulator
SG48_RS09710	COG0469	pyruvate kinase activity
SG48_RS09715	COG1560	Kdo2-lipid A biosynthetic process
SG48_RS09720	COG0739	heme binding
SG48_RS09725	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
SG48_RS09735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SG48_RS09760	COG0217	transcriptional regulatory protein
SG48_RS09765	COG0494	nUDIX hydrolase
SG48_RS09775	COG1335	isochorismatase
SG48_RS09780	COG1801	Protein of unknown function DUF72
SG48_RS09785	COG3788	relative of glutathione S-transferase, MAPEG superfamily
SG48_RS09800	COG0243	molybdopterin cofactor binding
SG48_RS09805	COG3005	denitrification pathway
SG48_RS09815	COG3102	Protein conserved in bacteria
SG48_RS09825	COG3755	Protein conserved in bacteria
SG48_RS09835	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SG48_RS09840	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SG48_RS09845	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
SG48_RS09850	COG0745	RESPONSE REGULATOR receiver
SG48_RS09855	COG2201	protein-glutamate methylesterase activity
SG48_RS09860	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SG48_RS09865	COG0840	transmembrane signaling receptor activity
SG48_RS09870	COG0840	transmembrane signaling receptor activity
SG48_RS09875	COG0835	chemotaxis
SG48_RS09880	COG0643	Histidine kinase
SG48_RS09880	COG2198	Histidine kinase
SG48_RS09885	COG1360	Flagellar Motor Protein
SG48_RS09890	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SG48_RS09905	COG0589	response to stress
SG48_RS09915	COG1877	trehalose-phosphatase activity
SG48_RS09920	COG1172	Belongs to the binding-protein-dependent transport system permease family
SG48_RS09925	COG1129	ABC transporter
SG48_RS09930	COG1879	ABC-type sugar transport system periplasmic component
SG48_RS09935	COG1528	Iron-storage protein
SG48_RS09955	COG1528	Iron-storage protein
SG48_RS09965	COG0814	amino acid
SG48_RS09970	COG3318	Belongs to the UPF0149 family
SG48_RS09970	COG3012	SEC-C Motif Domain Protein
SG48_RS10000	COG2197	response regulator
SG48_RS10015	COG2197	response regulator
SG48_RS10020	COG1126	abc transporter atp-binding protein
SG48_RS10025	COG0765	amino acid transport
SG48_RS10035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SG48_RS10045	COG1191	sigma factor activity
SG48_RS10050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SG48_RS10055	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SG48_RS10060	COG1516	flagellar protein fliS
SG48_RS10070	COG0366	Alpha amylase catalytic
SG48_RS10080	COG2391	methyltransferase activity
SG48_RS10085	COG0425	Belongs to the sulfur carrier protein TusA family
SG48_RS10090	COG2135	peptidase activity
SG48_RS10095	COG0454	-acetyltransferase
SG48_RS10120	COG1766	The M ring may be actively involved in energy transduction
SG48_RS10125	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SG48_RS10130	COG1317	bacterial-type flagellum organization
SG48_RS10135	COG1157	protein secretion by the type III secretion system
SG48_RS10140	COG2882	bacterial-type flagellum organization
SG48_RS10145	COG3144	bacterial-type flagellum assembly
SG48_RS10150	COG1580	Controls the rotational direction of flagella during chemotaxis
SG48_RS10155	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SG48_RS10160	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SG48_RS10165	COG3190	flagellar
SG48_RS10170	COG1338	Plays a role in the flagellum-specific transport system
SG48_RS10175	COG1987	bacterial-type flagellum assembly
SG48_RS10180	COG1684	flagellar biosynthetic protein fliR
SG48_RS10185	COG2197	response regulator
SG48_RS10205	COG3706	GGDEF domain
SG48_RS10210	COG5475	Uncharacterized small protein (DUF2158)
SG48_RS10215	COG2354	Protein conserved in bacteria
SG48_RS10220	COG0697	spore germination
SG48_RS10225	COG3727	T/G mismatch-specific endonuclease activity
SG48_RS10230	COG0270	DNA (cytosine-5-)-methyltransferase activity
SG48_RS10235	COG1418	mRNA catabolic process
SG48_RS10265	COG2205	protein histidine kinase activity
SG48_RS10270	COG0745	RESPONSE REGULATOR receiver
SG48_RS10275	COG2351	hydroxyisourate hydrolase activity
SG48_RS10280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SG48_RS10290	COG3443	Belongs to the bacterial solute-binding protein 9 family
SG48_RS10295	COG3038	cytochrome b561
SG48_RS10320	COG1388	LysM domain
SG48_RS10320	COG1470	cell adhesion involved in biofilm formation
SG48_RS10330	COG0477	Major facilitator Superfamily
SG48_RS10335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SG48_RS10340	COG0217	transcriptional regulatory protein
SG48_RS10350	COG0534	Mate efflux family protein
SG48_RS10360	COG0583	DNA-binding transcription factor activity
SG48_RS10365	COG0583	DNA-binding transcription factor activity
SG48_RS10375	COG1376	ErfK ybiS ycfS ynhG family protein
SG48_RS10390	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
SG48_RS10400	COG3039	Transposase
SG48_RS10420	COG4771	TonB-dependent receptor
SG48_RS10430	COG3468	outer membrane autotransporter barrel domain protein
SG48_RS10440	COG2003	Belongs to the UPF0758 family
SG48_RS10480	COG1289	transmembrane transporter activity
SG48_RS10490	COG1686	Belongs to the peptidase S11 family
SG48_RS10495	COG2925	Exonuclease
SG48_RS10500	COG0425	Belongs to the sulfur carrier protein TusA family
SG48_RS10505	COG2391	methyltransferase activity
SG48_RS10510	COG0531	amino acid
SG48_RS10515	COG0583	DNA-binding transcription factor activity
SG48_RS10520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SG48_RS10525	COG4115	mRNA cleavage
SG48_RS10530	COG2161	toxin-antitoxin pair type II binding
SG48_RS10540	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SG48_RS10550	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SG48_RS10550	COG0131	Imidazoleglycerol-phosphate dehydratase
SG48_RS10555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SG48_RS10570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SG48_RS10570	COG0140	phosphoribosyl-ATP diphosphatase activity
SG48_RS10575	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
SG48_RS10580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SG48_RS10585	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SG48_RS10600	COG0438	transferase activity, transferring glycosyl groups
SG48_RS10605	COG0110	maltose O-acetyltransferase activity
SG48_RS10610	COG0438	transferase activity, transferring glycosyl groups
SG48_RS10620	COG0562	UDP-galactopyranose mutase
SG48_RS10625	COG2244	polysaccharide biosynthetic process
SG48_RS10630	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SG48_RS10635	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SG48_RS10640	COG1091	dTDP-4-dehydrorhamnose reductase activity
SG48_RS10645	COG1088	dTDP-glucose 4,6-dehydratase activity
SG48_RS10650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SG48_RS10660	COG0438	transferase activity, transferring glycosyl groups
SG48_RS10665	COG2327	Polysaccharide pyruvyl transferase
SG48_RS10670	COG2244	polysaccharide biosynthetic process
SG48_RS10675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SG48_RS10680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SG48_RS10685	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SG48_RS10685	COG0662	Cupin 2, conserved barrel domain protein
SG48_RS10690	COG0297	glycogen (starch) synthase activity
SG48_RS10695	COG1051	belongs to the nudix hydrolase family
SG48_RS10700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SG48_RS10705	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SG48_RS10710	COG0110	maltose O-acetyltransferase activity
SG48_RS10715	COG1216	Glycosyl transferase, family 2
SG48_RS10725	COG0438	transferase activity, transferring glycosyl groups
SG48_RS10730	COG1045	serine acetyltransferase
SG48_RS10735	COG0463	Glycosyl transferase, family 2
SG48_RS10740	COG0489	protein tyrosine kinase activity
SG48_RS10740	COG3206	protein involved in exopolysaccharide biosynthesis
SG48_RS10745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SG48_RS10750	COG1596	polysaccharide export
SG48_RS10755	COG1253	flavin adenine dinucleotide binding
SG48_RS10760	COG2982	Protein involved in outer membrane biogenesis
SG48_RS10770	COG0572	uridine kinase
SG48_RS10775	COG5001	Diguanylate cyclase
SG48_RS10775	COG3447	MASE1 domain protein
SG48_RS10775	COG5002	protein histidine kinase activity
SG48_RS10780	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
SG48_RS10790	COG0443	Heat shock 70 kDa protein
SG48_RS10795	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
SG48_RS10800	COG3779	Protein conserved in bacteria
SG48_RS10805	COG0631	protein serine/threonine phosphatase activity
SG48_RS10810	COG4245	von Willebrand factor, type A
SG48_RS10835	COG2205	protein histidine kinase activity
SG48_RS10840	COG0745	RESPONSE REGULATOR receiver
SG48_RS10845	COG3422	double-strand break repair
SG48_RS10850	COG0826	peptidase U32
SG48_RS10885	COG2801	Transposase and inactivated derivatives
SG48_RS10895	COG1063	alcohol dehydrogenase
SG48_RS10900	COG3775	system Galactitol-specific IIC component
SG48_RS10905	COG3414	Phosphotransferase system galactitol-specific IIB component
SG48_RS10910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS10925	COG1830	Aldolase
SG48_RS10930	COG2211	Major facilitator Superfamily
SG48_RS10935	COG1397	ADP-ribosylglycohydrolase
SG48_RS10940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SG48_RS10945	COG2188	Transcriptional regulator
SG48_RS10950	COG3757	hydrolase, family 25
SG48_RS10955	COG0351	phosphomethylpyrimidine kinase
SG48_RS10970	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
SG48_RS10975	COG5455	response to cobalt ion
SG48_RS10980	COG3539	Fimbrial protein
SG48_RS10985	COG3188	usher protein
SG48_RS10990	COG3121	Chaperone
SG48_RS10995	COG3539	Fimbrial protein
SG48_RS11010	COG0489	protein tyrosine kinase activity
SG48_RS11030	COG3831	ATPase activity
SG48_RS11040	COG0714	Associated with various cellular activities
SG48_RS11045	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SG48_RS11050	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SG48_RS11055	COG4715	Zinc finger, swim domain protein
SG48_RS11060	COG4808	Protein conserved in bacteria
SG48_RS11065	COG4807	Protein conserved in bacteria
SG48_RS11070	COG3279	Response regulator of the LytR AlgR family
SG48_RS11075	COG3275	phosphorelay sensor kinase activity
SG48_RS11080	COG0789	Transcriptional regulator
SG48_RS11090	COG1174	glycine betaine transport
SG48_RS11095	COG1125	glycine betaine transport
SG48_RS11100	COG1174	glycine betaine transport
SG48_RS11105	COG1732	Glycine betaine
SG48_RS11110	COG1472	Belongs to the glycosyl hydrolase 3 family
SG48_RS11115	COG0277	FAD linked oxidase domain protein
SG48_RS11120	COG1686	Belongs to the peptidase S11 family
SG48_RS11130	COG0586	Pfam SNARE associated Golgi protein
SG48_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS11150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SG48_RS11160	COG1346	cytolysis
SG48_RS11170	COG2949	membrane
SG48_RS11180	COG0493	'glutamate synthase
SG48_RS11185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SG48_RS11185	COG0167	dihydroorotate dehydrogenase activity
SG48_RS11190	COG4211	Belongs to the binding-protein-dependent transport system permease family
SG48_RS11195	COG1129	ABC transporter
SG48_RS11200	COG1879	ABC-type sugar transport system periplasmic component
SG48_RS11205	COG1609	Transcriptional regulator
SG48_RS11215	COG2311	Membrane
SG48_RS11235	COG4771	TonB-dependent receptor
SG48_RS11240	COG0833	amino acid
SG48_RS11245	COG0583	DNA-binding transcription factor activity
SG48_RS11250	COG2855	membrane
SG48_RS11260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SG48_RS11260	COG1522	sequence-specific DNA binding
SG48_RS11265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SG48_RS11275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SG48_RS11280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SG48_RS11285	COG2313	pseudouridylate synthase activity
SG48_RS11290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SG48_RS11295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS11295	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SG48_RS11295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS11300	COG1105	Belongs to the carbohydrate kinase PfkB family
SG48_RS11305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS11305	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS11310	COG2814	Major facilitator Superfamily
SG48_RS11325	COG0246	Mannitol dehydrogenase
SG48_RS11330	COG0523	cobalamin synthesis protein
SG48_RS11335	COG0671	phosphoesterase, PA-phosphatase related
SG48_RS11340	COG0791	NLP P60 protein
SG48_RS11345	COG2200	EAL domain
SG48_RS11350	COG4166	transmembrane transport
SG48_RS11355	COG4174	ABC transporter (Permease)
SG48_RS11360	COG4239	(ABC) transporter, permease
SG48_RS11365	COG4172	Belongs to the ABC transporter superfamily
SG48_RS11375	COG2814	Major facilitator Superfamily
SG48_RS11380	COG1187	pseudouridine synthase activity
SG48_RS11385	COG1061	Type III restriction enzyme res subunit
SG48_RS11405	COG3083	sulfuric ester hydrolase activity
SG48_RS11415	COG3468	outer membrane autotransporter barrel domain protein
SG48_RS11430	COG2197	response regulator
SG48_RS11435	COG3088	subunit of a heme lyase
SG48_RS11435	COG4235	cytochrome complex assembly
SG48_RS11440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SG48_RS11445	COG1138	Cytochrome C-type biogenesis protein
SG48_RS11455	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SG48_RS11460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SG48_RS11465	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SG48_RS11470	COG4133	protoheme IX ABC transporter activity
SG48_RS11475	COG3005	denitrification pathway
SG48_RS11480	COG3043	anaerobic respiration
SG48_RS11485	COG0348	domain, Protein
SG48_RS11490	COG0437	4 iron, 4 sulfur cluster binding
SG48_RS11500	COG3062	negative regulation of establishment of protein localization
SG48_RS11505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS11505	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS11525	COG4615	Cyclic peptide transporter
SG48_RS11530	COG3145	DNA-N1-methyladenine dioxygenase activity
SG48_RS11535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SG48_RS11535	COG2169	Transcriptional regulator
SG48_RS11540	COG1477	protein flavinylation
SG48_RS11545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SG48_RS11560	COG2198	Histidine kinase
SG48_RS11560	COG0642	Histidine kinase
SG48_RS11565	COG2197	response regulator
SG48_RS11570	COG0784	Response regulator, receiver
SG48_RS11570	COG2205	protein histidine kinase activity
SG48_RS11575	COG3852	Histidine kinase
SG48_RS11580	COG2204	response regulator
SG48_RS11585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SG48_RS11590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SG48_RS11595	COG2031	fatty acid transporter
SG48_RS11600	COG0183	Belongs to the thiolase family
SG48_RS11605	COG4676	Protein conserved in bacteria
SG48_RS11610	COG5445	Predicted secreted protein (DUF2300)
SG48_RS11615	COG2373	Large extracellular alpha-helical protein
SG48_RS11625	COG3234	Protein of unknown function (DUF1175)
SG48_RS11630	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
SG48_RS11635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SG48_RS11645	COG3468	outer membrane autotransporter barrel domain protein
SG48_RS11655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SG48_RS11660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SG48_RS11665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SG48_RS11670	COG3642	lipopolysaccharide core region biosynthetic process
SG48_RS11675	COG0583	DNA-binding transcription factor activity
SG48_RS11680	COG0584	glycerophosphoryl diester phosphodiesterase
SG48_RS11685	COG2271	Major facilitator Superfamily
SG48_RS11690	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SG48_RS11700	COG0247	lactate metabolic process
SG48_RS11705	COG5464	transposase or invertase
SG48_RS11720	COG2271	Major facilitator Superfamily
SG48_RS11730	COG1414	Transcriptional regulator
SG48_RS11795	COG0318	PFAM AMP-dependent synthetase and ligase
SG48_RS11805	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SG48_RS11820	COG1169	isochorismate synthase
SG48_RS11825	COG4575	ribosome binding
SG48_RS11830	COG2153	protein acetylation
SG48_RS11840	COG5160	protein modification by small protein removal
SG48_RS11845	COG2304	oxidoreductase activity
SG48_RS11850	COG2234	aminopeptidase activity
SG48_RS11870	COG0457	Tetratricopeptide repeat
SG48_RS11880	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SG48_RS11885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SG48_RS11895	COG0839	Belongs to the complex I subunit 6 family
SG48_RS11910	COG1034	ATP synthesis coupled electron transport
SG48_RS11915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SG48_RS11920	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
SG48_RS11940	COG0583	DNA-binding transcription factor activity
SG48_RS11945	COG0436	Aminotransferase
SG48_RS11955	COG0490	domain, Protein
SG48_RS11955	COG0471	metal ion transport
SG48_RS11960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SG48_RS11980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SG48_RS11985	COG0857	belongs to the CobB CobQ family
SG48_RS11985	COG0280	phosphate acetyltransferase
SG48_RS11990	COG1288	antiporter activity
SG48_RS11995	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SG48_RS12000	COG0622	Phosphoesterase
SG48_RS12005	COG0625	glutathione transferase activity
SG48_RS12010	COG0625	glutathione transferase activity
SG48_RS12015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SG48_RS12020	COG1090	epimerase
SG48_RS12025	COG5464	transposase or invertase
SG48_RS12030	COG4598	ABC transporter
SG48_RS12035	COG4160	amino acid transport
SG48_RS12040	COG4215	(ABC) transporter
SG48_RS12045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SG48_RS12050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SG48_RS12055	COG0163	prenyltransferase activity
SG48_RS12060	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SG48_RS12065	COG1286	toxin biosynthetic process
SG48_RS12070	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
SG48_RS12075	COG0285	dihydrofolate synthase activity
SG48_RS12085	COG0586	Pfam SNARE associated Golgi protein
SG48_RS12095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SG48_RS12110	COG2814	Major facilitator Superfamily
SG48_RS12115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SG48_RS12130	COG3101	peptidyl-lysine hydroxylation
SG48_RS12135	COG0730	response to heat
SG48_RS12150	COG2890	protein-(glutamine-N5) methyltransferase activity
SG48_RS12165	COG3539	Fimbrial protein
SG48_RS12170	COG3539	Fimbrial protein
SG48_RS12175	COG3539	Fimbrial protein
SG48_RS12180	COG3121	Chaperone
SG48_RS12190	COG3539	Fimbrial protein
SG48_RS12195	COG2062	phosphohistidine phosphatase, SixA
SG48_RS12210	COG3691	Protein conserved in bacteria
SG48_RS12215	COG2067	long-chain fatty acid transport protein
SG48_RS12225	COG2853	Lipoprotein
SG48_RS12230	COG2116	formate transmembrane transporter activity
SG48_RS12240	COG0582	viral genome integration into host DNA
SG48_RS12245	COG2246	polysaccharide biosynthetic process
SG48_RS12250	COG0463	Glycosyl transferase, family 2
SG48_RS12275	COG4725	Belongs to the MT-A70-like family
SG48_RS12285	COG1846	Transcriptional regulator
SG48_RS12295	COG5532	Uncharacterized conserved protein (DUF2303)
SG48_RS12300	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
SG48_RS12320	COG0583	DNA-binding transcription factor activity
SG48_RS12325	COG2610	gluconate transmembrane transporter activity
SG48_RS12335	COG0477	Major facilitator Superfamily
SG48_RS12340	COG1566	PFAM secretion protein HlyD family protein
SG48_RS12345	COG2197	response regulator
SG48_RS12350	COG0784	Response regulator, receiver
SG48_RS12350	COG2205	protein histidine kinase activity
SG48_RS12350	COG2198	Histidine kinase
SG48_RS12350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SG48_RS12355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SG48_RS12360	COG0679	Auxin Efflux Carrier
SG48_RS12365	COG0028	Belongs to the TPP enzyme family
SG48_RS12395	COG1560	Kdo2-lipid A biosynthetic process
SG48_RS12400	COG0436	Aminotransferase
SG48_RS12405	COG3275	phosphorelay sensor kinase activity
SG48_RS12410	COG3279	Response regulator of the LytR AlgR family
SG48_RS12415	COG2207	Transcriptional regulator
SG48_RS12420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS12420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SG48_RS12420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS12425	COG1363	Peptidase, m42
SG48_RS12430	COG0006	proline dipeptidase activity
SG48_RS12435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS12440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS12470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SG48_RS12475	COG3385	transposase activity
SG48_RS12480	COG2199	diguanylate cyclase activity
SG48_RS12480	COG2200	EAL domain
SG48_RS12495	COG3415	Transposase
SG48_RS12500	COG3415	Transposase
SG48_RS12530	COG0583	DNA-binding transcription factor activity
SG48_RS12540	COG2211	Major facilitator Superfamily
SG48_RS12545	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SG48_RS12555	COG0583	DNA-binding transcription factor activity
SG48_RS12560	COG0385	Bile acid
SG48_RS12565	COG3530	Putative quorum-sensing-regulated virulence factor
SG48_RS12585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SG48_RS12590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS12595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SG48_RS12600	COG2190	(PTS) system
SG48_RS12615	COG3831	ATPase activity
SG48_RS12615	COG4884	unkown
SG48_RS12620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SG48_RS12625	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SG48_RS12630	COG4208	sulfate ABC transporter
SG48_RS12635	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SG48_RS12640	COG4150	thiosulfate binding
SG48_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS12660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS12660	COG1263	PTS System
SG48_RS12665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SG48_RS12670	COG2837	iron assimilation
SG48_RS12685	COG0456	acetyltransferase
SG48_RS12690	COG0860	N-Acetylmuramoyl-L-alanine amidase
SG48_RS12700	COG2207	Transcriptional regulator
SG48_RS12705	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SG48_RS12710	COG4816	utilization protein
SG48_RS12720	COG4303	Ethanolamine ammonia lyase large subunit
SG48_RS12725	COG0582	viral genome integration into host DNA
SG48_RS12770	COG4819	ethanolamine utilization protein
SG48_RS12775	COG3192	ethanolamine utilization protein
SG48_RS12780	COG1454	alcohol dehydrogenase
SG48_RS12785	COG4820	ethanolamine utilization protein (EutJ)
SG48_RS12790	COG1012	belongs to the aldehyde dehydrogenase family
SG48_RS12795	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SG48_RS12800	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SG48_RS12805	COG0280	phosphate acetyltransferase
SG48_RS12810	COG4812	Cobalamin adenosyltransferase
SG48_RS12815	COG4766	ethanolamine catabolic process
SG48_RS12820	COG4917	ethanolamine utilization protein
SG48_RS12825	COG4810	utilization protein
SG48_RS12830	COG0280	phosphate acetyltransferase
SG48_RS12830	COG0281	malic enzyme
SG48_RS12835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SG48_RS12840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SG48_RS12845	COG5342	invasion associated locus B
SG48_RS12855	COG0493	'glutamate synthase
SG48_RS12855	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS12860	COG3850	Histidine kinase
SG48_RS12865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SG48_RS12875	COG1393	Belongs to the ArsC family
SG48_RS12890	COG0400	carboxylic ester hydrolase activity
SG48_RS12895	COG1444	tRNA N-acetyltransferase activity
SG48_RS12900	COG2321	neutral zinc metallopeptidase
SG48_RS12915	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
SG48_RS12925	COG2716	regulation of RNA biosynthetic process
SG48_RS12930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SG48_RS12935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS12940	COG0651	ATP synthesis coupled electron transport
SG48_RS12945	COG0650	Formate hydrogenlyase subunit 4
SG48_RS12950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SG48_RS12955	COG4237	Hydrogenase 4 membrane
SG48_RS12960	COG0651	ATP synthesis coupled electron transport
SG48_RS12965	COG3261	NADH dehydrogenase
SG48_RS12965	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
SG48_RS12970	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SG48_RS12975	COG3260	NADH ubiquinone oxidoreductase 20
SG48_RS12985	COG3604	Transcriptional regulator
SG48_RS12990	COG2116	formate transmembrane transporter activity
SG48_RS12995	COG0628	permease
SG48_RS13000	COG4783	chaperone-mediated protein folding
SG48_RS13005	COG1393	Belongs to the ArsC family
SG48_RS13015	COG2233	PERMEase
SG48_RS13030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SG48_RS13035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SG48_RS13040	COG0248	Ppx GppA phosphatase
SG48_RS13045	COG2200	EAL domain
SG48_RS13060	COG3133	Outer membrane lipoprotein
SG48_RS13075	COG0516	GMP reductase activity
SG48_RS13075	COG0517	IMP dehydrogenase activity
SG48_RS13085	COG1645	bacterial-type flagellum-dependent swarming motility
SG48_RS13095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SG48_RS13100	COG2976	Protein conserved in bacteria
SG48_RS13130	COG4953	penicillin-binding protein 1C
SG48_RS13135	COG2373	Large extracellular alpha-helical protein
SG48_RS13140	COG2897	thiosulfate sulfurtransferase activity
SG48_RS13155	COG2975	iron-sulfur cluster assembly
SG48_RS13160	COG0633	Ferredoxin
SG48_RS13180	COG0822	iron-sulfur transferase activity
SG48_RS13200	COG0483	inositol monophosphate 1-phosphatase activity
SG48_RS13205	COG1073	alpha beta
SG48_RS13210	COG3711	transcriptional antiterminator
SG48_RS13215	COG2814	Major facilitator Superfamily
SG48_RS13220	COG0583	DNA-binding transcription factor activity
SG48_RS13225	COG4638	Rieske (2fe-2S)
SG48_RS13250	COG2259	Doxx family
SG48_RS13255	COG2017	converts alpha-aldose to the beta-anomer
SG48_RS13260	COG1063	alcohol dehydrogenase
SG48_RS13265	COG1172	Belongs to the binding-protein-dependent transport system permease family
SG48_RS13270	COG1129	ABC transporter
SG48_RS13275	COG1879	ABC-type sugar transport system periplasmic component
SG48_RS13280	COG0457	Tetratricopeptide repeat
SG48_RS13285	COG1940	carbohydrate kinase activity
SG48_RS13295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SG48_RS13295	COG1017	nitric oxide dioxygenase activity
SG48_RS13300	COG0347	Belongs to the P(II) protein family
SG48_RS13305	COG2204	response regulator
SG48_RS13310	COG3170	Tfp pilus assembly protein FimV
SG48_RS13315	COG2205	protein histidine kinase activity
SG48_RS13320	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SG48_RS13320	COG0047	phosphoribosylformylglycinamidine synthase activity
SG48_RS13335	COG0560	Phosphoserine phosphatase
SG48_RS13340	COG1737	Transcriptional regulator
SG48_RS13345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS13370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SG48_RS13390	COG0681	Belongs to the peptidase S26 family
SG48_RS13400	COG3086	response to oxidative stress
SG48_RS13405	COG3026	antisigma factor binding
SG48_RS13410	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
SG48_RS13415	COG1595	DNA-templated transcription, initiation
SG48_RS13425	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SG48_RS13435	COG0513	Belongs to the DEAD box helicase family
SG48_RS13445	COG0583	DNA-binding transcription factor activity
SG48_RS13465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SG48_RS13475	COG3118	belongs to the thioredoxin family
SG48_RS13480	COG3148	PFAM DTW domain containing protein
SG48_RS13485	COG1042	CoA-binding domain protein
SG48_RS13485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SG48_RS13485	COG0045	succinate-CoA ligase (ADP-forming) activity
SG48_RS13490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SG48_RS13495	COG5544	Lipoprotein
SG48_RS13500	COG0477	Major facilitator Superfamily
SG48_RS13530	COG0542	response to heat
SG48_RS13535	COG1496	oxidoreductase activity
SG48_RS13540	COG0564	pseudouridine synthase activity
SG48_RS13545	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SG48_RS13555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SG48_RS13560	COG0077	Prephenate dehydratase
SG48_RS13560	COG1605	Chorismate mutase
SG48_RS13565	COG1605	Chorismate mutase
SG48_RS13565	COG0287	Prephenate dehydrogenase
SG48_RS13570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SG48_RS13585	COG2199	diguanylate cyclase activity
SG48_RS13590	COG2885	chlorophyll binding
SG48_RS13615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SG48_RS13620	COG4137	Cytochrome C assembly protein
SG48_RS13625	COG4536	flavin adenine dinucleotide binding
SG48_RS13645	COG0497	DNA recombination
SG48_RS13650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SG48_RS13660	COG2867	negative regulation of translational initiation
SG48_RS13670	COG0582	viral genome integration into host DNA
SG48_RS13680	COG3311	Transcriptional regulator
SG48_RS13685	COG4983	Phage plasmid primase, P4 family domain protein
SG48_RS13695	COG1204	response to ionizing radiation
SG48_RS13705	COG1479	Protein of unknown function DUF262
SG48_RS13720	COG3596	GTP binding
SG48_RS13730	COG2378	regulation of single-species biofilm formation
SG48_RS13770	COG2003	Belongs to the UPF0758 family
SG48_RS13785	COG3468	outer membrane autotransporter barrel domain protein
SG48_RS13820	COG0366	Alpha amylase catalytic
SG48_RS13825	COG0366	Alpha amylase catalytic
SG48_RS13830	COG0366	Alpha amylase catalytic
SG48_RS13840	COG0579	oxidoreductase
SG48_RS13845	COG1012	belongs to the aldehyde dehydrogenase family
SG48_RS13850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SG48_RS13855	COG1113	amino acid transport
SG48_RS13860	COG1802	Transcriptional regulator
SG48_RS13865	COG1652	LysM domain
SG48_RS13870	COG0401	homolog of Blt101
SG48_RS13875	COG0640	Transcriptional regulator
SG48_RS13880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SG48_RS13885	COG2916	Histone family protein nucleoid-structuring protein H-NS
SG48_RS13900	COG4575	ribosome binding
SG48_RS13905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SG48_RS13915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SG48_RS13920	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SG48_RS13925	COG4175	Glycine betaine
SG48_RS13930	COG4176	ABC-type proline glycine betaine transport system permease component
SG48_RS13935	COG2113	Glycine betaine
SG48_RS13945	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SG48_RS13955	COG1846	Transcriptional regulator
SG48_RS13960	COG1566	PFAM secretion protein HlyD family protein
SG48_RS13965	COG2814	Major facilitator Superfamily
SG48_RS13980	COG1238	metal cluster binding
SG48_RS13985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SG48_RS14020	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SG48_RS14045	COG1546	Belongs to the CinA family
SG48_RS14050	COG2951	lytic endotransglycosylase activity
SG48_RS14055	COG3730	PTS system glucitol sorbitol-specific
SG48_RS14060	COG3732	PTS system glucitol sorbitol-specific
SG48_RS14065	COG3731	PTS system glucitol sorbitol-specific IIA component
SG48_RS14070	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS14075	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS14080	COG1349	DNA-binding transcription factor activity
SG48_RS14085	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SG48_RS14085	COG0517	IMP dehydrogenase activity
SG48_RS14105	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SG48_RS14110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS14115	COG1609	Transcriptional regulator
SG48_RS14120	COG1263	PTS System
SG48_RS14120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS14125	COG2723	6-phospho-beta-galactosidase activity
SG48_RS14130	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SG48_RS14140	COG3260	NADH ubiquinone oxidoreductase 20
SG48_RS14145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SG48_RS14150	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
SG48_RS14150	COG3261	NADH dehydrogenase
SG48_RS14155	COG0650	Formate hydrogenlyase subunit 4
SG48_RS14160	COG0651	ATP synthesis coupled electron transport
SG48_RS14165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS14180	COG0375	protein maturation
SG48_RS14185	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SG48_RS14190	COG0298	carbon dioxide binding
SG48_RS14195	COG0409	Hydrogenase expression formation protein
SG48_RS14200	COG0309	Hydrogenase expression formation protein (HypE)
SG48_RS14205	COG3604	Transcriptional regulator
SG48_RS14220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SG48_RS14225	COG1349	DNA-binding transcription factor activity
SG48_RS14230	COG2084	Dehydrogenase
SG48_RS14235	COG3395	kinase activity
SG48_RS14240	COG0235	Class ii aldolase
SG48_RS14245	COG3622	Belongs to the hyi family
SG48_RS14250	COG2610	gluconate transmembrane transporter activity
SG48_RS14255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SG48_RS14260	COG4942	peptidase
SG48_RS14260	COG1388	LysM domain
SG48_RS14315	COG2234	aminopeptidase activity
SG48_RS14320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SG48_RS14325	COG1518	maintenance of DNA repeat elements
SG48_RS14340	COG1857	crispr-associated protein
SG48_RS14355	COG1203	CRISPR-associated helicase, Cas3
SG48_RS14370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SG48_RS14375	COG0720	synthase
SG48_RS14380	COG0644	oxidoreductase
SG48_RS14385	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SG48_RS14390	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SG48_RS14395	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SG48_RS14400	COG2086	electron transfer activity
SG48_RS14405	COG0477	Major facilitator Superfamily
SG48_RS14410	COG0277	FAD linked oxidase domain protein
SG48_RS14415	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS14420	COG2223	nitrite transmembrane transporter activity
SG48_RS14425	COG1070	Carbohydrate kinase
SG48_RS14430	COG0602	queuosine metabolic process
SG48_RS14440	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
SG48_RS14455	COG3956	TIGRFAM MazG family protein
SG48_RS14460	COG2337	Toxic component of a toxin-antitoxin (TA) module
SG48_RS14465	COG2336	PFAM SpoVT AbrB
SG48_RS14470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SG48_RS14475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SG48_RS14480	COG3850	Histidine kinase
SG48_RS14480	COG4999	Histidine kinase
SG48_RS14480	COG3437	response regulator, receiver
SG48_RS14480	COG2205	protein histidine kinase activity
SG48_RS14485	COG4948	Mandelate Racemase Muconate Lactonizing
SG48_RS14490	COG4948	Mandelate Racemase Muconate Lactonizing
SG48_RS14495	COG2271	Major facilitator Superfamily
SG48_RS14500	COG0716	FMN binding
SG48_RS14505	COG0564	pseudouridine synthase activity
SG48_RS14510	COG3098	single-species biofilm formation
SG48_RS14530	COG1611	Belongs to the LOG family
SG48_RS14535	COG0814	amino acid
SG48_RS14540	COG1760	l-serine dehydratase
SG48_RS14550	COG1454	alcohol dehydrogenase
SG48_RS14555	COG0235	Class ii aldolase
SG48_RS14560	COG0738	Major facilitator superfamily
SG48_RS14570	COG1070	Carbohydrate kinase
SG48_RS14580	COG1349	DNA-binding transcription factor activity
SG48_RS14590	COG2363	Small membrane protein
SG48_RS14595	COG0583	DNA-binding transcription factor activity
SG48_RS14605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SG48_RS14610	COG2166	iron-sulfur cluster assembly
SG48_RS14615	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SG48_RS14620	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
SG48_RS14640	COG0860	N-Acetylmuramoyl-L-alanine amidase
SG48_RS14645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SG48_RS14645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SG48_RS14650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SG48_RS14655	COG1074	ATP-dependent DNA helicase activity
SG48_RS14660	COG1025	Belongs to the peptidase M16 family
SG48_RS14665	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SG48_RS14670	COG4967	type IV pilus modification protein PilV
SG48_RS14680	COG4795	General secretion pathway protein
SG48_RS14685	COG2165	general secretion pathway protein
SG48_RS14700	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
SG48_RS14725	COG0861	Integral membrane protein TerC family
SG48_RS14735	COG0667	Aldo Keto reductase
SG48_RS14750	COG1609	Transcriptional regulator
SG48_RS14760	COG0583	DNA-binding transcription factor activity
SG48_RS14765	COG1794	racemase activity, acting on amino acids and derivatives
SG48_RS14770	COG2814	Major facilitator Superfamily
SG48_RS14775	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS14785	COG0183	Belongs to the thiolase family
SG48_RS14790	COG0814	amino acid
SG48_RS14795	COG2771	luxR family
SG48_RS14800	COG3710	Transcriptional regulator
SG48_RS14820	COG0457	Tetratricopeptide repeat
SG48_RS14825	COG3710	Transcriptional regulator
SG48_RS14825	COG0457	Tetratricopeptide repeat
SG48_RS14840	COG2197	response regulator
SG48_RS14845	COG2197	response regulator
SG48_RS14875	COG3387	PFAM Glycoside hydrolase 15-related
SG48_RS14880	COG3387	PFAM Glycoside hydrolase 15-related
SG48_RS14890	COG4942	peptidase
SG48_RS14895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SG48_RS14900	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SG48_RS14905	COG2080	2 iron, 2 sulfur cluster binding
SG48_RS14910	COG3829	transcription factor binding
SG48_RS14915	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SG48_RS14920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SG48_RS14925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SG48_RS14935	COG0549	Belongs to the carbamate kinase family
SG48_RS14940	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SG48_RS14940	COG3608	succinylglutamate desuccinylase aspartoacylase
SG48_RS14945	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SG48_RS14950	COG2068	MobA-Related Protein
SG48_RS14955	COG0493	'glutamate synthase
SG48_RS14955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS14960	COG0402	S-adenosylhomocysteine deaminase activity
SG48_RS14965	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SG48_RS14970	COG2080	2 iron, 2 sulfur cluster binding
SG48_RS14970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SG48_RS14975	COG2233	PERMEase
SG48_RS14980	COG0402	S-adenosylhomocysteine deaminase activity
SG48_RS14985	COG2252	PERMEase
SG48_RS14990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS14995	COG0493	'glutamate synthase
SG48_RS14995	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS15005	COG2233	PERMEase
SG48_RS15020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SG48_RS15030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SG48_RS15035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SG48_RS15040	COG4974	Belongs to the 'phage' integrase family
SG48_RS15045	COG0716	FMN binding
SG48_RS15055	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
SG48_RS15065	COG1272	protein, Hemolysin III
SG48_RS15075	COG2723	6-phospho-beta-galactosidase activity
SG48_RS15080	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS15100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SG48_RS15105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SG48_RS15110	COG0006	proline dipeptidase activity
SG48_RS15125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SG48_RS15130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SG48_RS15150	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SG48_RS15150	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SG48_RS15155	COG1703	isobutyryl-CoA mutase activity
SG48_RS15160	COG1024	Enoyl-CoA hydratase
SG48_RS15165	COG0427	acetyl-CoA hydrolase
SG48_RS15170	COG0583	DNA-binding transcription factor activity
SG48_RS15175	COG2968	Membrane
SG48_RS15180	COG1279	arginine transmembrane transporter activity
SG48_RS15185	COG0668	transmembrane transport
SG48_RS15190	COG0191	fructose-bisphosphate aldolase activity
SG48_RS15205	COG1072	(Pantothenic acid kinase))
SG48_RS15210	COG3722	fumarate hydratase activity
SG48_RS15215	COG1494	fructose-1,6-bisphosphatase
SG48_RS15220	COG1063	alcohol dehydrogenase
SG48_RS15225	COG2213	PTS system mannitol-specific
SG48_RS15230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS15235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SG48_RS15240	COG0501	Belongs to the peptidase M48B family
SG48_RS15250	COG1166	arginine decarboxylase activity
SG48_RS15275	COG2814	Major facilitator Superfamily
SG48_RS15285	COG2356	endonuclease I
SG48_RS15290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SG48_RS15295	COG0189	ligase activity
SG48_RS15310	COG2805	Type II/IV secretion system protein
SG48_RS15315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SG48_RS15320	COG0762	integral membrane protein
SG48_RS15330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SG48_RS15335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SG48_RS15345	COG0252	asparaginase activity
SG48_RS15360	COG3171	Protein conserved in bacteria
SG48_RS15370	COG1194	a g-specific adenine glycosylase
SG48_RS15385	COG2211	Major facilitator Superfamily
SG48_RS15390	COG1982	Orn Lys Arg decarboxylase major
SG48_RS15395	COG1811	Na channel or pump
SG48_RS15405	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
SG48_RS15415	COG3031	protein transport across the cell outer membrane
SG48_RS15425	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SG48_RS15430	COG3064	Membrane
SG48_RS15440	COG1620	l-lactate permease
SG48_RS15445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SG48_RS15450	COG3193	protein, possibly involved in utilization of glycolate and propanediol
SG48_RS15455	COG0247	lactate metabolic process
SG48_RS15460	COG0277	FAD linked oxidase domain protein
SG48_RS15465	COG0277	FAD linked oxidase domain protein
SG48_RS15470	COG2186	Transcriptional regulator
SG48_RS15475	COG0456	acetyltransferase
SG48_RS15485	COG2244	polysaccharide biosynthetic process
SG48_RS15490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SG48_RS15495	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SG48_RS15500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SG48_RS15505	COG0306	phosphate transporter
SG48_RS15510	COG0754	glutathionylspermidine amidase activity
SG48_RS15515	COG0625	glutathione transferase activity
SG48_RS15520	COG0298	carbon dioxide binding
SG48_RS15530	COG1773	rubredoxin
SG48_RS15535	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SG48_RS15540	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SG48_RS15545	COG5557	Pfam Polysulphide reductase, NrfD
SG48_RS15550	COG0437	4 iron, 4 sulfur cluster binding
SG48_RS15555	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SG48_RS15575	COG0667	Aldo Keto reductase
SG48_RS15585	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS15590	COG0848	biopolymer transport protein
SG48_RS15595	COG0811	peptide transport
SG48_RS15605	COG0626	cystathionine gamma-synthase activity
SG48_RS15610	COG0586	Pfam SNARE associated Golgi protein
SG48_RS15615	COG2207	Transcriptional regulator
SG48_RS15625	COG1979	alcohol dehydrogenase
SG48_RS15630	COG0656	L-ascorbic acid biosynthetic process
SG48_RS15640	COG4238	major outer membrane lipoprotein
SG48_RS15645	COG1032	radical SAM domain protein
SG48_RS15650	COG2132	Multicopper oxidase
SG48_RS15655	COG0204	Acyl-transferase
SG48_RS15660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SG48_RS15665	COG4166	transmembrane transport
SG48_RS15670	COG2944	sequence-specific DNA binding
SG48_RS15680	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
SG48_RS15685	COG3111	PFAM Bacterial OB fold (BOF) protein
SG48_RS15690	COG0745	RESPONSE REGULATOR receiver
SG48_RS15695	COG0642	Histidine kinase
SG48_RS15705	COG2249	NAD(P)H dehydrogenase (quinone) activity
SG48_RS15710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SG48_RS15715	COG0187	DNA topoisomerase II activity
SG48_RS15720	COG3150	esterase
SG48_RS15725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SG48_RS15730	COG3151	Protein conserved in bacteria
SG48_RS15735	COG0494	nUDIX hydrolase
SG48_RS15740	COG1538	Outer membrane efflux protein
SG48_RS15755	COG0754	glutathionylspermidine amidase activity
SG48_RS15760	COG3384	dioxygenase
SG48_RS15780	COG2960	long-chain fatty acid transporting porin activity
SG48_RS15785	COG3539	Fimbrial protein
SG48_RS15800	COG3188	usher protein
SG48_RS15805	COG3121	Chaperone
SG48_RS15810	COG3539	Fimbrial protein
SG48_RS15820	COG1585	Membrane protein implicated in regulation of membrane protease activity
SG48_RS15825	COG2268	Band 7 protein
SG48_RS15850	COG3025	triphosphatase activity
SG48_RS15860	COG4991	sh3 domain protein
SG48_RS15875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SG48_RS15885	COG0583	DNA-binding transcription factor activity
SG48_RS15890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SG48_RS15895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SG48_RS15900	COG0471	metal ion transport
SG48_RS15910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SG48_RS15915	COG0358	DNA primase activity
SG48_RS15920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SG48_RS15935	COG2375	cellular response to nickel ion
SG48_RS15940	COG1695	Transcriptional regulator
SG48_RS15945	COG0840	transmembrane signaling receptor activity
SG48_RS15955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SG48_RS15960	COG1609	Transcriptional regulator
SG48_RS15965	COG3250	beta-galactosidase activity
SG48_RS15970	COG2731	YhcH YjgK YiaL family protein
SG48_RS15975	COG0531	amino acid
SG48_RS15985	COG3408	Glycogen debranching enzyme
SG48_RS15985	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SG48_RS15990	COG1902	pentaerythritol trinitrate reductase activity
SG48_RS15990	COG0446	pyridine nucleotide-disulphide oxidoreductase
SG48_RS15995	COG5499	transcription regulator containing HTH domain
SG48_RS16000	COG4680	protein conserved in bacteria
SG48_RS16015	COG1451	nucleotide metabolic process
SG48_RS16020	COG2949	membrane
SG48_RS16025	COG0673	inositol 2-dehydrogenase activity
SG48_RS16030	COG0861	Integral membrane protein TerC family
SG48_RS16035	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
SG48_RS16045	COG2721	sulfolactate sulfo-lyase activity
SG48_RS16055	COG2271	Major facilitator Superfamily
SG48_RS16060	COG2186	Transcriptional regulator
SG48_RS16065	COG0586	Pfam SNARE associated Golgi protein
SG48_RS16075	COG1422	Protein of unknown function (DUF1090)
SG48_RS16080	COG4575	ribosome binding
SG48_RS16085	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
SG48_RS16095	COG2259	Doxx family
SG48_RS16100	COG0435	Glutathione S-transferase
SG48_RS16105	COG3152	Membrane
SG48_RS16110	COG3152	Membrane
SG48_RS16115	COG0583	DNA-binding transcription factor activity
SG48_RS16120	COG1741	Belongs to the pirin family
SG48_RS16135	COG0814	amino acid
SG48_RS16140	COG1760	l-serine dehydratase
SG48_RS16145	COG0251	oxidation-reduction process
SG48_RS16150	COG1882	Formate acetyltransferase
SG48_RS16155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SG48_RS16165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SG48_RS16170	COG0583	DNA-binding transcription factor activity
SG48_RS16190	COG1929	Belongs to the glycerate kinase type-1 family
SG48_RS16195	COG2084	Dehydrogenase
SG48_RS16205	COG2271	Major facilitator Superfamily
SG48_RS16210	COG2721	sulfolactate sulfo-lyase activity
SG48_RS16215	COG2002	toxin-antitoxin pair type II binding
SG48_RS16225	COG1349	DNA-binding transcription factor activity
SG48_RS16235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS16245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SG48_RS16250	COG2222	sugar isomerase
SG48_RS16260	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS16265	COG3715	PTS system
SG48_RS16270	COG3716	PTS system mannose fructose sorbose family IID component
SG48_RS16275	COG0363	glucosamine-6-phosphate deaminase activity
SG48_RS16280	COG3539	Fimbrial protein
SG48_RS16285	COG3121	Chaperone
SG48_RS16290	COG3188	usher protein
SG48_RS16295	COG3539	Fimbrial protein
SG48_RS16300	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SG48_RS16305	COG3107	peptidoglycan biosynthetic process
SG48_RS16320	COG2823	Periplasmic or secreted lipoprotein
SG48_RS16325	COG0701	Predicted permease
SG48_RS16330	COG0702	epimerase
SG48_RS16335	COG0693	protein deglycase activity
SG48_RS16350	COG3153	acetyltransferase
SG48_RS16355	COG3154	lipid carrier protein
SG48_RS16360	COG0826	peptidase U32
SG48_RS16365	COG0826	peptidase U32
SG48_RS16370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SG48_RS16375	COG0814	amino acid
SG48_RS16385	COG0513	Belongs to the DEAD box helicase family
SG48_RS16420	COG0195	Participates in both transcription termination and antitermination
SG48_RS16440	COG2194	sulfuric ester hydrolase activity
SG48_RS16450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SG48_RS16460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SG48_RS16465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SG48_RS16475	COG1534	Rna-binding protein
SG48_RS16480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SG48_RS16485	COG2027	D-alanyl-D-alanine carboxypeptidase
SG48_RS16495	COG0697	spore germination
SG48_RS16510	COG0142	geranyltranstransferase activity
SG48_RS16515	COG3423	Transcriptional regulator
SG48_RS16525	COG5007	Belongs to the BolA IbaG family
SG48_RS16530	COG3113	response to antibiotic
SG48_RS16535	COG2854	intermembrane phospholipid transfer
SG48_RS16540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SG48_RS16545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SG48_RS16550	COG1127	ABC transporter
SG48_RS16555	COG0530	calcium, potassium:sodium antiporter activity
SG48_RS16560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SG48_RS16560	COG0517	IMP dehydrogenase activity
SG48_RS16565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SG48_RS16570	COG3117	lipopolysaccharide transmembrane transporter activity
SG48_RS16575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
SG48_RS16580	COG1137	ATPase activity
SG48_RS16585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SG48_RS16590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SG48_RS16605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS16610	COG0515	serine threonine protein kinase
SG48_RS16620	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
SG48_RS16625	COG0784	Response regulator, receiver
SG48_RS16625	COG2198	Histidine kinase
SG48_RS16625	COG5002	protein histidine kinase activity
SG48_RS16630	COG1242	4 iron, 4 sulfur cluster binding
SG48_RS16635	COG0067	glutamate synthase
SG48_RS16635	COG0069	glutamate synthase activity
SG48_RS16635	COG0070	glutamate synthase
SG48_RS16640	COG0493	'glutamate synthase
SG48_RS16645	COG3539	Fimbrial protein
SG48_RS16650	COG3121	Chaperone
SG48_RS16655	COG3188	usher protein
SG48_RS16675	COG3539	Fimbrial protein
SG48_RS16680	COG4804	nuclease activity
SG48_RS16685	COG2731	YhcH YjgK YiaL family protein
SG48_RS16715	COG3069	C4-dicarboxylate transmembrane transporter activity
SG48_RS16720	COG2969	positive regulation of protein catabolic process
SG48_RS16725	COG0625	glutathione transferase activity
SG48_RS16740	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SG48_RS16745	COG3105	Protein conserved in bacteria
SG48_RS16750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SG48_RS16755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SG48_RS16775	COG2732	(Barnase) inhibitor
SG48_RS16780	COG1289	transmembrane transporter activity
SG48_RS16795	COG0583	DNA-binding transcription factor activity
SG48_RS16800	COG0312	modulator of DNA gyrase
SG48_RS16805	COG3164	Protein of unknown function
SG48_RS16810	COG1530	ribonuclease E activity
SG48_RS16815	COG0424	maF-like protein
SG48_RS16820	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
SG48_RS16825	COG1792	Involved in formation and maintenance of cell shape
SG48_RS16830	COG1077	Cell shape determining protein MreB Mrl
SG48_RS16840	COG2200	EAL domain
SG48_RS16840	COG2199	diguanylate cyclase activity
SG48_RS16845	COG0604	alcohol dehydrogenase
SG48_RS16865	COG0511	ligase activity, forming carbon-carbon bonds
SG48_RS16870	COG0439	Biotin carboxylase
SG48_RS16875	COG3924	membrane
SG48_RS16880	COG4145	pantothenate transmembrane transporter activity
SG48_RS16890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SG48_RS16900	COG2189	Belongs to the N(4) N(6)-methyltransferase family
SG48_RS16910	COG1309	transcriptional regulator
SG48_RS16915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SG48_RS16920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SG48_RS16935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SG48_RS16940	COG4597	amino acid ABC transporter
SG48_RS16945	COG0765	amino acid transport
SG48_RS16950	COG1126	abc transporter atp-binding protein
SG48_RS16990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SG48_RS17010	COG0551	DNA topoisomerase type I activity
SG48_RS17020	COG0758	DNA mediated transformation
SG48_RS17040	COG0569	domain protein
SG48_RS17050	COG3036	rescue of stalled ribosome
SG48_RS17055	COG0789	Transcriptional regulator
SG48_RS17095	COG0201	protein transport
SG48_RS17185	COG0089	rRNA binding
SG48_RS17210	COG3409	Peptidoglycan-binding domain 1 protein
SG48_RS17210	COG3267	Type II secretory pathway component ExeA
SG48_RS17215	COG3031	protein transport across the cell outer membrane
SG48_RS17220	COG1450	Type ii and iii secretion system protein
SG48_RS17225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SG48_RS17230	COG1459	type II secretion system
SG48_RS17235	COG2165	general secretion pathway protein
SG48_RS17240	COG2165	general secretion pathway protein
SG48_RS17245	COG2165	general secretion pathway protein
SG48_RS17250	COG4795	General secretion pathway protein
SG48_RS17255	COG3156	type II secretion system protein K
SG48_RS17260	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
SG48_RS17265	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
SG48_RS17270	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SG48_RS17275	COG2193	ferroxidase activity
SG48_RS17280	COG2906	2 iron, 2 sulfur cluster binding
SG48_RS17285	COG3979	chitinase
SG48_RS17325	COG2964	Protein conserved in bacteria
SG48_RS17330	COG0545	Peptidyl-prolyl cis-trans isomerase
SG48_RS17340	COG1047	Peptidyl-prolyl cis-trans
SG48_RS17345	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
SG48_RS17360	COG0488	(ABC) transporter
SG48_RS17365	COG0429	hydrolase of the alpha beta-hydrolase fold
SG48_RS17375	COG3954	Phosphoribulokinase
SG48_RS17380	COG1765	OsmC-like protein
SG48_RS17390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SG48_RS17395	COG1289	transmembrane transporter activity
SG48_RS17400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SG48_RS17405	COG0512	Glutamine amidotransferase of anthranilate synthase
SG48_RS17410	COG2184	nucleotidyltransferase activity
SG48_RS17420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SG48_RS17430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SG48_RS17435	COG2146	nitrite reductase [NAD(P)H] activity
SG48_RS17440	COG2116	formate transmembrane transporter activity
SG48_RS17455	COG0531	amino acid
SG48_RS17460	COG2222	sugar isomerase
SG48_RS17465	COG1082	Xylose isomerase domain protein TIM barrel
SG48_RS17470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SG48_RS17475	COG2188	Transcriptional regulator
SG48_RS17480	COG0626	cystathionine gamma-synthase activity
SG48_RS17495	COG1735	metal-dependent hydrolase with the TIM-barrel fold
SG48_RS17500	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SG48_RS17505	COG3457	Alanine racemase
SG48_RS17515	COG2188	Transcriptional regulator
SG48_RS17520	COG0180	Tryptophanyl-tRNA synthetase
SG48_RS17525	COG0546	phosphoglycolate phosphatase activity
SG48_RS17530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SG48_RS17535	COG0338	D12 class N6 adenine-specific DNA methyltransferase
SG48_RS17540	COG3266	domain, Protein
SG48_RS17555	COG4796	Type ii and iii secretion system protein
SG48_RS17570	COG3166	PFAM Fimbrial assembly family protein
SG48_RS17575	COG4972	Pilus assembly protein
SG48_RS17580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SG48_RS17585	COG0494	nUDIX hydrolase
SG48_RS17595	COG1011	Hydrolase
SG48_RS17600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SG48_RS17610	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
SG48_RS17635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SG48_RS17640	COG2183	response to ionizing radiation
SG48_RS17645	COG1918	ferrous iron import across plasma membrane
SG48_RS17650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SG48_RS17660	COG5464	transposase or invertase
SG48_RS17670	COG1040	competence protein
SG48_RS17680	COG2610	gluconate transmembrane transporter activity
SG48_RS17685	COG1640	4-alpha-glucanotransferase
SG48_RS17690	COG0058	SHG alpha-glucan phosphorylase activity
SG48_RS17705	COG1690	Belongs to the RtcB family
SG48_RS17710	COG4650	regulator
SG48_RS17715	COG1349	DNA-binding transcription factor activity
SG48_RS17730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SG48_RS17735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SG48_RS17740	COG0058	SHG alpha-glucan phosphorylase activity
SG48_RS17765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SG48_RS17770	COG2095	MarC family integral membrane protein
SG48_RS17775	COG2610	gluconate transmembrane transporter activity
SG48_RS17780	COG3265	gluconokinase activity
SG48_RS17785	COG1609	Transcriptional regulator
SG48_RS17790	COG1741	Belongs to the pirin family
SG48_RS17795	COG0673	inositol 2-dehydrogenase activity
SG48_RS17800	COG1247	-acetyltransferase
SG48_RS17805	COG3157	Type VI secretion system effector, Hcp
SG48_RS17825	COG0405	Gamma-glutamyltransferase
SG48_RS17835	COG0584	glycerophosphoryl diester phosphodiesterase
SG48_RS17840	COG3842	ATPase activity
SG48_RS17845	COG0395	ABC-type sugar transport system, permease component
SG48_RS17850	COG1175	transmembrane transport
SG48_RS17855	COG1653	transport
SG48_RS17865	COG0410	ABC transporter
SG48_RS17870	COG0411	ABC transporter
SG48_RS17875	COG4177	L-phenylalanine transmembrane transporter activity
SG48_RS17880	COG0559	Belongs to the binding-protein-dependent transport system permease family
SG48_RS17885	COG0683	leucine binding
SG48_RS17890	COG0456	acetyltransferase
SG48_RS17900	COG0683	leucine binding
SG48_RS17905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SG48_RS17910	COG2177	Part of the ABC transporter FtsEX involved in
SG48_RS17915	COG2884	Cell division ATP-binding protein ftsE
SG48_RS17920	COG0552	protein localization to endoplasmic reticulum
SG48_RS17925	COG0742	ribosomal rna small subunit methyltransferase
SG48_RS17930	COG3776	membrane
SG48_RS17940	COG3714	YhhN family
SG48_RS17945	COG2217	Heavy metal translocating P-type atpase
SG48_RS17955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SG48_RS17965	COG0477	Major facilitator Superfamily
SG48_RS17970	COG0628	permease
SG48_RS17975	COG2091	lysine biosynthetic process via aminoadipic acid
SG48_RS17980	COG0747	negative chemotaxis
SG48_RS17985	COG0601	transmembrane transport
SG48_RS17990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SG48_RS17995	COG0444	Belongs to the ABC transporter superfamily
SG48_RS18000	COG1124	(ABC) transporter
SG48_RS18010	COG3209	COG3209 Rhs family protein
SG48_RS18025	COG5433	transposase activity
SG48_RS18030	COG0842	Transport permease protein
SG48_RS18035	COG0842	Transport permease protein
SG48_RS18035	COG1129	ABC transporter
SG48_RS18040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SG48_RS18070	COG2081	HI0933 family
SG48_RS18075	COG0306	phosphate transporter
SG48_RS18085	COG0589	response to stress
SG48_RS18090	COG3104	oligopeptide transport
SG48_RS18100	COG0339	signal peptide processing
SG48_RS18105	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
SG48_RS18110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SG48_RS18125	COG0640	Transcriptional regulator
SG48_RS18130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SG48_RS18135	COG1393	Belongs to the ArsC family
SG48_RS18155	COG3065	identical protein binding
SG48_RS18160	COG2197	response regulator
SG48_RS18165	COG1285	pathogenesis
SG48_RS18180	COG3247	response to pH
SG48_RS18185	COG2771	luxR family
SG48_RS18195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SG48_RS18200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SG48_RS18205	COG2207	Transcriptional regulator
SG48_RS18210	COG2207	Transcriptional regulator
SG48_RS18215	COG0076	glutamate decarboxylase activity
SG48_RS18220	COG1858	cytochrome C peroxidase
SG48_RS18230	COG2197	response regulator
SG48_RS18235	COG0583	DNA-binding transcription factor activity
SG48_RS18240	COG1295	ribonuclease BN
SG48_RS18245	COG0477	Major facilitator Superfamily
SG48_RS18250	COG2982	Protein involved in outer membrane biogenesis
SG48_RS18255	COG2200	EAL domain
SG48_RS18265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SG48_RS18270	COG0612	Peptidase, M16
SG48_RS18280	COG2199	diguanylate cyclase activity
SG48_RS18280	COG2200	EAL domain
SG48_RS18285	COG0457	Tetratricopeptide repeat
SG48_RS18285	COG3118	belongs to the thioredoxin family
SG48_RS18290	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SG48_RS18295	COG1215	transferase activity, transferring glycosyl groups
SG48_RS18300	COG1215	transferase activity, transferring glycosyl groups
SG48_RS18325	COG2194	sulfuric ester hydrolase activity
SG48_RS18340	COG0814	amino acid
SG48_RS18345	COG4608	Belongs to the ABC transporter superfamily
SG48_RS18350	COG0444	Belongs to the ABC transporter superfamily
SG48_RS18355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SG48_RS18360	COG0601	transmembrane transport
SG48_RS18370	COG0747	negative chemotaxis
SG48_RS18385	COG2194	sulfuric ester hydrolase activity
SG48_RS18390	COG2223	nitrite transmembrane transporter activity
SG48_RS18395	COG5571	outer membrane autotransporter
SG48_RS18400	COG2818	Glycosylase
SG48_RS18405	COG0456	acetyltransferase
SG48_RS18410	COG0243	molybdopterin cofactor binding
SG48_RS18415	COG2885	chlorophyll binding
SG48_RS18430	COG2944	sequence-specific DNA binding
SG48_RS18435	COG1278	Cold shock
SG48_RS18445	COG2963	transposase activity
SG48_RS18450	COG2801	Transposase and inactivated derivatives
SG48_RS18460	COG0752	glycyl-tRNA synthetase alpha subunit
SG48_RS18470	COG3274	enterobacterial common antigen metabolic process
SG48_RS18475	COG4682	membrane
SG48_RS18480	COG4682	membrane
SG48_RS18485	COG1070	Carbohydrate kinase
SG48_RS18495	COG4213	ABC transporter substrate-binding protein
SG48_RS18500	COG1129	ABC transporter
SG48_RS18505	COG4214	carbohydrate transport
SG48_RS18510	COG2207	Transcriptional regulator
SG48_RS18510	COG1609	Transcriptional regulator
SG48_RS18515	COG2992	FlgJ-related protein
SG48_RS18520	COG0366	Alpha amylase catalytic
SG48_RS18525	COG3977	Valine--pyruvate aminotransferase
SG48_RS18535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SG48_RS18540	COG1414	Transcriptional regulator
SG48_RS18550	COG2731	YhcH YjgK YiaL family protein
SG48_RS18555	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SG48_RS18560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SG48_RS18565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SG48_RS18570	COG1070	Carbohydrate kinase
SG48_RS18575	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SG48_RS18580	COG3623	hexulose-6-phosphate isomerase
SG48_RS18585	COG0235	Class ii aldolase
SG48_RS18590	COG3713	MltA-interacting MipA family protein
SG48_RS18595	COG0583	DNA-binding transcription factor activity
SG48_RS18600	COG1566	PFAM secretion protein HlyD family protein
SG48_RS18615	COG1012	belongs to the aldehyde dehydrogenase family
SG48_RS18620	COG1454	alcohol dehydrogenase
SG48_RS18625	COG3276	selenocysteine insertion sequence binding
SG48_RS18635	COG0625	glutathione transferase activity
SG48_RS18640	COG3209	COG3209 Rhs family protein
SG48_RS18645	COG1413	lyase activity
SG48_RS18650	COG3209	COG3209 Rhs family protein
SG48_RS18655	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SG48_RS18665	COG1566	PFAM secretion protein HlyD family protein
SG48_RS18675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS18675	COG2213	PTS system mannitol-specific
SG48_RS18685	COG3722	fumarate hydratase activity
SG48_RS18700	COG1620	l-lactate permease
SG48_RS18705	COG2186	Transcriptional regulator
SG48_RS18715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SG48_RS18720	COG1045	serine acetyltransferase
SG48_RS18735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SG48_RS18740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SG48_RS18745	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SG48_RS18750	COG4942	peptidase
SG48_RS18755	COG2861	carbohydrate metabolic process
SG48_RS18760	COG1216	Glycosyl transferase, family 2
SG48_RS18770	COG0156	8-amino-7-oxononanoate synthase activity
SG48_RS18785	COG0859	PFAM glycosyl transferase family 9
SG48_RS18790	COG0859	PFAM glycosyl transferase family 9
SG48_RS18795	COG3307	-O-antigen
SG48_RS18800	COG0859	PFAM glycosyl transferase family 9
SG48_RS18810	COG3642	lipopolysaccharide core region biosynthetic process
SG48_RS18815	COG1442	glycosyl transferase family 8
SG48_RS18820	COG1442	glycosyl transferase family 8
SG48_RS18825	COG0438	transferase activity, transferring glycosyl groups
SG48_RS18830	COG4641	Protein conserved in bacteria
SG48_RS18830	COG0438	transferase activity, transferring glycosyl groups
SG48_RS18835	COG0515	serine threonine protein kinase
SG48_RS18840	COG0438	transferase activity, transferring glycosyl groups
SG48_RS18845	COG0859	PFAM glycosyl transferase family 9
SG48_RS18850	COG1519	Transferase
SG48_RS18880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SG48_RS18885	COG0756	dUTP diphosphatase activity
SG48_RS18905	COG1561	YicC-like family, N-terminal region
SG48_RS18910	COG3645	SOS response
SG48_RS18915	COG2860	membrane
SG48_RS18925	COG0194	GDP metabolic process
SG48_RS18935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SG48_RS18940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SG48_RS18945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SG48_RS18950	COG0786	glutamate:sodium symporter activity
SG48_RS18955	COG2233	PERMEase
SG48_RS18960	COG2982	Protein involved in outer membrane biogenesis
SG48_RS18965	COG1501	Belongs to the glycosyl hydrolase 31 family
SG48_RS18970	COG2211	Major facilitator Superfamily
SG48_RS18985	COG2814	Major facilitator Superfamily
SG48_RS18990	COG0697	spore germination
SG48_RS18995	COG1464	Belongs to the NlpA lipoprotein family
SG48_RS19020	COG2252	PERMEase
SG48_RS19030	COG2271	Major facilitator Superfamily
SG48_RS19035	COG2271	Major facilitator Superfamily
SG48_RS19040	COG3851	Histidine kinase
SG48_RS19045	COG2197	response regulator
SG48_RS19050	COG0440	acetolactate synthase activity
SG48_RS19055	COG0028	Belongs to the TPP enzyme family
SG48_RS19080	COG2814	Major facilitator Superfamily
SG48_RS19085	COG0641	radical SAM
SG48_RS19095	COG2149	membrane
SG48_RS19105	COG3119	arylsulfatase activity
SG48_RS19110	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SG48_RS19115	COG2207	Transcriptional regulator
SG48_RS19125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS19125	COG1263	PTS System
SG48_RS19130	COG1263	PTS System
SG48_RS19135	COG2188	Transcriptional regulator
SG48_RS19155	COG5645	(Lipo)protein
SG48_RS19160	COG0823	Involved in the tonB-independent uptake of proteins
SG48_RS19165	COG0644	oxidoreductase
SG48_RS19170	COG2271	Major facilitator Superfamily
SG48_RS19180	COG0800	Aldolase
SG48_RS19185	COG3734	2-keto-3-deoxy-galactonokinase
SG48_RS19190	COG2186	Transcriptional regulator
SG48_RS19200	COG0561	phosphatase activity
SG48_RS19205	COG3753	Protein conserved in bacteria
SG48_RS19215	COG0187	DNA topoisomerase II activity
SG48_RS19225	COG0592	DNA-directed DNA polymerase activity
SG48_RS19270	COG0814	amino acid
SG48_RS19285	COG2091	lysine biosynthetic process via aminoadipic acid
SG48_RS19290	COG0431	NADPH-dependent FMN reductase
SG48_RS19295	COG2252	PERMEase
SG48_RS19300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SG48_RS19310	COG3196	Protein conserved in bacteria
SG48_RS19315	COG0363	glucosamine-6-phosphate deaminase activity
SG48_RS19320	COG2382	esterase
SG48_RS19330	COG2723	6-phospho-beta-galactosidase activity
SG48_RS19335	COG2190	(PTS) system
SG48_RS19335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS19335	COG1263	PTS System
SG48_RS19340	COG3711	transcriptional antiterminator
SG48_RS19345	COG0704	Plays a role in the regulation of phosphate uptake
SG48_RS19350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SG48_RS19355	COG0581	inorganic phosphate transmembrane transporter activity
SG48_RS19360	COG0573	inorganic phosphate transmembrane transporter activity
SG48_RS19365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SG48_RS19370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SG48_RS19420	COG3312	ion transport
SG48_RS19435	COG0716	FMN binding
SG48_RS19440	COG1522	sequence-specific DNA binding
SG48_RS19470	COG1129	ABC transporter
SG48_RS19475	COG1172	Belongs to the binding-protein-dependent transport system permease family
SG48_RS19480	COG1879	ABC-type sugar transport system periplasmic component
SG48_RS19485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SG48_RS19490	COG1609	Transcriptional regulator
SG48_RS19495	COG0477	Major facilitator Superfamily
SG48_RS19500	COG2186	Transcriptional regulator
SG48_RS19540	COG3085	chromosome segregation
SG48_RS19545	COG0606	chelatase, subunit chli
SG48_RS19560	COG3978	acetolactate synthase activity
SG48_RS19565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SG48_RS19575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SG48_RS19580	COG0583	DNA-binding transcription factor activity
SG48_RS19590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SG48_RS19600	COG0210	DNA helicase
SG48_RS19615	COG3118	belongs to the thioredoxin family
SG48_RS19625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SG48_RS19635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SG48_RS19640	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
SG48_RS19645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SG48_RS19650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SG48_RS19655	COG1088	dTDP-glucose 4,6-dehydratase activity
SG48_RS19660	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SG48_RS19665	COG0456	acetyltransferase
SG48_RS19670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SG48_RS19675	COG2244	polysaccharide biosynthetic process
SG48_RS19695	COG1113	amino acid transport
SG48_RS19720	COG0641	radical SAM
SG48_RS19725	COG3119	arylsulfatase activity
SG48_RS19730	COG3071	HemY protein
SG48_RS19735	COG2959	enzyme of heme biosynthesis
SG48_RS19740	COG1587	Uroporphyrinogen-III synthase
SG48_RS19750	COG3072	Adenylate cyclase
SG48_RS19760	COG5567	small periplasmic lipoprotein
SG48_RS19770	COG3159	Protein conserved in bacteria
SG48_RS19780	COG1011	Hydrolase
SG48_RS19785	COG0210	DNA helicase
SG48_RS19790	COG3698	Phosphodiester glycosidase
SG48_RS19800	COG0598	Magnesium transport protein CorA
SG48_RS19815	COG2962	Rard protein
SG48_RS19820	COG2050	protein possibly involved in aromatic compounds catabolism
SG48_RS19825	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
SG48_RS19830	COG0514	ATP-dependent DNA helicase (RecQ)
SG48_RS19835	COG1280	lysine exporter protein (LysE YggA)
SG48_RS19840	COG1280	lysine exporter protein (LysE YggA)
SG48_RS19845	COG2267	carboxylic ester hydrolase activity
SG48_RS19850	COG0561	phosphatase activity
SG48_RS19855	COG0697	spore germination
SG48_RS19860	COG0583	DNA-binding transcription factor activity
SG48_RS19870	COG0412	Dienelactone hydrolase
SG48_RS19875	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SG48_RS19880	COG1322	Protein conserved in bacteria
SG48_RS19890	COG3165	ubiquinone biosynthetic process from chorismate
SG48_RS19900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SG48_RS19905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SG48_RS19910	COG0805	protein transport
SG48_RS19915	COG0084	hydrolase, TatD family'
SG48_RS19920	COG0250	Participates in transcription elongation, termination and antitermination
SG48_RS19925	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SG48_RS19930	COG0543	2 iron, 2 sulfur cluster binding
SG48_RS19935	COG0183	Belongs to the thiolase family
SG48_RS19950	COG1739	Uncharacterized protein family UPF0029
SG48_RS19955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SG48_RS19960	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
SG48_RS19990	COG1763	Mo-molybdopterin cofactor biosynthetic process
SG48_RS19995	COG0746	molybdenum cofactor guanylyltransferase activity
SG48_RS20000	COG3084	Protein conserved in bacteria
SG48_RS20005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SG48_RS20010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SG48_RS20015	COG5339	Protein conserved in bacteria
SG48_RS20020	COG0204	Acyl-transferase
SG48_RS20030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SG48_RS20030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SG48_RS20045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SG48_RS20055	COG2204	response regulator
SG48_RS20060	COG3852	Histidine kinase
SG48_RS20065	COG0174	glutamine synthetase
SG48_RS20075	COG1217	gtp-binding protein TYPA
SG48_RS20080	COG2188	Transcriptional regulator
SG48_RS20085	COG1082	Xylose isomerase domain protein TIM barrel
SG48_RS20090	COG2271	Major facilitator Superfamily
SG48_RS20095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SG48_RS20100	COG2211	Major facilitator Superfamily
SG48_RS20105	COG2211	Major facilitator Superfamily
SG48_RS20110	COG1501	Belongs to the glycosyl hydrolase 31 family
SG48_RS20115	COG2017	converts alpha-aldose to the beta-anomer
SG48_RS20120	COG2942	2-epimerase
SG48_RS20125	COG3684	Belongs to the aldolase LacD family
SG48_RS20130	COG2084	Dehydrogenase
SG48_RS20135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SG48_RS20140	COG1349	DNA-binding transcription factor activity
SG48_RS20145	COG1011	Hydrolase
SG48_RS20160	COG0456	acetyltransferase
SG48_RS20165	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SG48_RS20170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SG48_RS20185	COG2864	formate dehydrogenase
SG48_RS20190	COG0437	4 iron, 4 sulfur cluster binding
SG48_RS20195	COG3383	formate dehydrogenase (NAD+) activity
SG48_RS20195	COG0243	molybdopterin cofactor binding
SG48_RS20200	COG0243	molybdopterin cofactor binding
SG48_RS20200	COG3383	formate dehydrogenase (NAD+) activity
SG48_RS20215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS20215	COG3711	transcriptional antiterminator
SG48_RS20220	COG1363	Peptidase, m42
SG48_RS20225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS20225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS20230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS20275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SG48_RS20290	COG2258	MOSC domain
SG48_RS20295	COG2205	protein histidine kinase activity
SG48_RS20300	COG0745	RESPONSE REGULATOR receiver
SG48_RS20305	COG3678	ATP-independent chaperone mediated protein folding
SG48_RS20320	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
SG48_RS20340	COG3152	Membrane
SG48_RS20345	COG3691	Protein conserved in bacteria
SG48_RS20350	COG0589	response to stress
SG48_RS20355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SG48_RS20360	COG1494	fructose-1,6-bisphosphatase
SG48_RS20370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SG48_RS20385	COG1575	Belongs to the MenA family. Type 1 subfamily
SG48_RS20400	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SG48_RS20405	COG1609	Transcriptional regulator
SG48_RS20410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SG48_RS20420	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
SG48_RS20430	COG0626	cystathionine gamma-synthase activity
SG48_RS20435	COG0527	aspartate kinase activity
SG48_RS20435	COG0460	homoserine dehydrogenase
SG48_RS20445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SG48_RS20455	COG0697	spore germination
SG48_RS20460	COG3738	Protein conserved in bacteria
SG48_RS20470	COG0371	Dehydrogenase
SG48_RS20475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SG48_RS20480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS20480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SG48_RS20480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS20485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS20490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS20495	COG1882	Formate acetyltransferase
SG48_RS20500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SG48_RS20505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SG48_RS20510	COG2207	Transcriptional regulator
SG48_RS20515	COG2194	sulfuric ester hydrolase activity
SG48_RS20535	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SG48_RS20550	COG0583	DNA-binding transcription factor activity
SG48_RS20575	COG4206	TonB-dependent receptor
SG48_RS20605	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SG48_RS20610	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SG48_RS20610	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SG48_RS20650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SG48_RS20655	COG0250	Participates in transcription elongation, termination and antitermination
SG48_RS20695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SG48_RS20705	COG2104	thiamine diphosphate biosynthetic process
SG48_RS20710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SG48_RS20745	COG3068	Protein conserved in bacteria
SG48_RS20760	COG3678	ATP-independent chaperone mediated protein folding
SG48_RS20765	COG4191	Histidine kinase
SG48_RS20770	COG2204	response regulator
SG48_RS20775	COG0151	Belongs to the GarS family
SG48_RS20790	COG0456	acetyltransferase
SG48_RS20800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SG48_RS20805	COG2224	Isocitrate lyase
SG48_RS20820	COG1414	Transcriptional regulator
SG48_RS20825	COG1410	methionine synthase
SG48_RS20825	COG0646	methionine synthase
SG48_RS20830	COG1283	sodium-dependent phosphate transmembrane transporter activity
SG48_RS20840	COG1187	pseudouridine synthase activity
SG48_RS20850	COG0527	aspartate kinase activity
SG48_RS20875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SG48_RS20895	COG2814	Major facilitator Superfamily
SG48_RS20895	COG0477	Major facilitator Superfamily
SG48_RS20900	COG3833	ABC-type maltose transport systems, permease component
SG48_RS20905	COG1175	transmembrane transport
SG48_RS20910	COG2182	Extracellular solute-binding protein
SG48_RS20920	COG3842	ATPase activity
SG48_RS20940	COG1357	PFAM Pentapeptide repeats (8 copies)
SG48_RS20960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SG48_RS20970	COG0534	Mate efflux family protein
SG48_RS20975	COG3237	CsbD-like
SG48_RS20980	COG0735	belongs to the Fur family
SG48_RS20995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SG48_RS21005	COG0604	alcohol dehydrogenase
SG48_RS21010	COG0305	Participates in initiation and elongation during chromosome replication
SG48_RS21015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SG48_RS21020	COG1448	Aminotransferase
SG48_RS21030	COG3700	Belongs to the class B bacterial acid phosphatase family
SG48_RS21035	COG0432	Pfam Uncharacterised protein family UPF0047
SG48_RS21040	COG2315	Protein conserved in bacteria
SG48_RS21045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SG48_RS21050	COG0629	single-stranded DNA binding
SG48_RS21060	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SG48_RS21065	COG2207	Transcriptional regulator
SG48_RS21070	COG0789	Transcriptional regulator
SG48_RS21075	COG2252	PERMEase
SG48_RS21080	COG0025	NhaP-type Na H and K H
SG48_RS21085	COG1357	PFAM Pentapeptide repeats (8 copies)
SG48_RS21095	COG3162	membrane
SG48_RS21100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SG48_RS21110	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
SG48_RS21115	COG0437	4 iron, 4 sulfur cluster binding
SG48_RS21120	COG3301	Polysulphide reductase, NrfD
SG48_RS21125	COG1138	Cytochrome C-type biogenesis protein
SG48_RS21130	COG3088	subunit of a heme lyase
SG48_RS21135	COG4235	cytochrome complex assembly
SG48_RS21140	COG1301	dicarboxylic acid transport
SG48_RS21145	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SG48_RS21150	COG3383	formate dehydrogenase (NAD+) activity
SG48_RS21155	COG3383	formate dehydrogenase (NAD+) activity
SG48_RS21160	COG1538	Outer membrane efflux protein
SG48_RS21165	COG1289	transmembrane transporter activity
SG48_RS21170	COG1566	PFAM secretion protein HlyD family protein
SG48_RS21180	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SG48_RS21185	COG1940	carbohydrate kinase activity
SG48_RS21190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SG48_RS21195	COG1172	Belongs to the binding-protein-dependent transport system permease family
SG48_RS21200	COG1129	ABC transporter
SG48_RS21205	COG1879	ABC-type sugar transport system periplasmic component
SG48_RS21210	COG1737	Transcriptional regulator
SG48_RS21215	COG0698	ribose 5-phosphate isomerase
SG48_RS21225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SG48_RS21230	COG0456	acetyltransferase
SG48_RS21235	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
SG48_RS21240	COG3454	Phosphonate metabolism
SG48_RS21245	COG4778	phosphonate C-P lyase system protein PhnL
SG48_RS21250	COG4107	phosphonate C-P lyase system protein PhnK
SG48_RS21255	COG3627	carbon phosphorus lyase activity
SG48_RS21260	COG3626	phosphonate metabolism
SG48_RS21265	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
SG48_RS21270	COG3624	Phosphonate C-P lyase system protein PhnG
SG48_RS21275	COG2188	Transcriptional regulator
SG48_RS21285	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SG48_RS21290	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SG48_RS21295	COG2764	glyoxalase bleomycin resistance protein dioxygenase
SG48_RS21300	COG2824	Alkylphosphonate utilization operon protein PhnA
SG48_RS21305	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SG48_RS21315	COG0477	Major facilitator Superfamily
SG48_RS21325	COG0642	Histidine kinase
SG48_RS21330	COG0745	RESPONSE REGULATOR receiver
SG48_RS21335	COG2194	sulfuric ester hydrolase activity
SG48_RS21340	COG0531	amino acid
SG48_RS21345	COG2207	Transcriptional regulator
SG48_RS21350	COG1982	Orn Lys Arg decarboxylase major
SG48_RS21355	COG2169	Transcriptional regulator
SG48_RS21365	COG1486	melibiose metabolic process
SG48_RS21370	COG2211	Major facilitator Superfamily
SG48_RS21375	COG3647	Membrane
SG48_RS21380	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SG48_RS21380	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SG48_RS21385	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SG48_RS21395	COG4565	transcriptional regulatory protein
SG48_RS21400	COG3290	protein histidine kinase activity
SG48_RS21405	COG3592	Divergent 4Fe-4S mono-cluster
SG48_RS21410	COG2388	GCN5-related N-acetyl-transferase
SG48_RS21430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SG48_RS21435	COG3104	oligopeptide transport
SG48_RS21440	COG1982	Orn Lys Arg decarboxylase major
SG48_RS21445	COG0531	amino acid
SG48_RS21450	COG3710	Transcriptional regulator
SG48_RS21460	COG1309	transcriptional regulator
SG48_RS21465	COG4232	protein-disulfide reductase activity
SG48_RS21475	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SG48_RS21480	COG1027	Aspartate ammonia-lyase
SG48_RS21485	COG3030	protein affecting phage T7 exclusion by the F plasmid
SG48_RS21490	COG0531	amino acid
SG48_RS21515	COG1509	lysine 2,3-aminomutase activity
SG48_RS21525	COG5510	response to toxic substance
SG48_RS21530	COG5510	response to toxic substance
SG48_RS21535	COG2076	Multidrug Resistance protein
SG48_RS21540	COG3040	lipid binding
SG48_RS21545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SG48_RS21560	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SG48_RS21565	COG1053	succinate dehydrogenase
SG48_RS21575	COG0531	amino acid
SG48_RS21590	COG1511	domain protein
SG48_RS21590	COG3264	Mechanosensitive ion channel
SG48_RS21625	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SG48_RS21630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SG48_RS21630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SG48_RS21635	COG0802	atpase or kinase
SG48_RS21640	COG0860	N-Acetylmuramoyl-L-alanine amidase
SG48_RS21660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SG48_RS21665	COG0330	HflC and HflK could
SG48_RS21670	COG0330	HflC and HflK could
SG48_RS21675	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
SG48_RS21690	COG0557	exoribonuclease II activity
SG48_RS21695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SG48_RS21700	COG3789	protein conserved in bacteria
SG48_RS21705	COG1842	Phage shock protein A
SG48_RS21715	COG3766	membrane
SG48_RS21720	COG5463	Belongs to the UPF0441 family
SG48_RS21725	COG0754	glutathionylspermidine amidase activity
SG48_RS21730	COG1960	acyl-CoA dehydrogenase activity
SG48_RS21740	COG3650	response to hydrogen peroxide
SG48_RS21745	COG1073	alpha beta
SG48_RS21760	COG3037	sugar-specific permease SgaT UlaA
SG48_RS21765	COG3414	Phosphotransferase system galactitol-specific IIB component
SG48_RS21770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS21810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SG48_RS21825	COG1309	transcriptional regulator
SG48_RS21830	COG3061	Opacity-associated protein A
SG48_RS21835	COG0545	Peptidyl-prolyl cis-trans isomerase
SG48_RS21840	COG1113	amino acid transport
SG48_RS21850	COG0697	spore germination
SG48_RS21855	COG0702	epimerase
SG48_RS21860	COG1733	regulation of RNA biosynthetic process
SG48_RS21865	COG0737	Belongs to the 5'-nucleotidase family
SG48_RS21870	COG1218	3'(2'),5'-bisphosphate nucleotidase
SG48_RS21880	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
SG48_RS21890	COG1253	flavin adenine dinucleotide binding
SG48_RS21905	COG0729	surface antigen
SG48_RS21910	COG2911	Protein conserved in bacteria
SG48_RS21915	COG2105	PFAM AIG2 family protein
SG48_RS21920	COG2336	PFAM SpoVT AbrB
SG48_RS21925	COG2337	Toxic component of a toxin-antitoxin (TA) module
SG48_RS21930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SG48_RS21935	COG1879	ABC-type sugar transport system periplasmic component
SG48_RS21940	COG1129	ABC transporter
SG48_RS21945	COG1172	Belongs to the binding-protein-dependent transport system permease family
SG48_RS21950	COG1172	Belongs to the binding-protein-dependent transport system permease family
SG48_RS21960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SG48_RS21970	COG0312	modulator of DNA gyrase
SG48_RS21975	COG3783	Cytochrome b(562)
SG48_RS21980	COG0602	queuosine metabolic process
SG48_RS21985	COG1328	CTP reductase activity
SG48_RS21990	COG0366	Alpha amylase catalytic
SG48_RS21995	COG1263	PTS System
SG48_RS21995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SG48_RS22000	COG1609	Transcriptional regulator
SG48_RS22005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SG48_RS22010	COG0251	oxidation-reduction process
SG48_RS22035	COG0251	oxidation-reduction process
SG48_RS22040	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS22045	COG1309	transcriptional regulator
SG48_RS22050	COG2731	YhcH YjgK YiaL family protein
SG48_RS22060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SG48_RS22065	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
SG48_RS22070	COG0456	acetyltransferase
SG48_RS22075	COG4269	membrane
SG48_RS22080	COG0525	valine-tRNA ligase activity
SG48_RS22085	COG2927	DNA polymerase III (CHI subunit)
SG48_RS22095	COG0795	lipopolysaccharide-transporting ATPase activity
SG48_RS22100	COG0795	lipopolysaccharide-transporting ATPase activity
SG48_RS22105	COG0433	COG0433 Predicted ATPase
SG48_RS22110	COG1609	Transcriptional regulator
SG48_RS22115	COG2610	gluconate transmembrane transporter activity
SG48_RS22120	COG1028	Short-chain dehydrogenase reductase Sdr
SG48_RS22125	COG1063	alcohol dehydrogenase
SG48_RS22130	COG3265	gluconokinase activity
SG48_RS22135	COG1064	alcohol dehydrogenase
SG48_RS22145	COG0582	viral genome integration into host DNA
SG48_RS22185	COG3385	transposase activity
SG48_RS22190	COG2814	Major facilitator Superfamily
SG48_RS22195	COG0673	inositol 2-dehydrogenase activity
SG48_RS22215	COG2826	transposase and inactivated derivatives, IS30 family
SG48_RS22230	COG2085	NADP oxidoreductase coenzyme F420-dependent
SG48_RS22235	COG1120	ATPase activity
SG48_RS22240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SG48_RS22245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SG48_RS22250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SG48_RS22255	COG4772	TonB-dependent receptor
SG48_RS22260	COG3712	iron ion homeostasis
SG48_RS22265	COG1595	DNA-templated transcription, initiation
SG48_RS22285	COG2390	Transcriptional regulator
SG48_RS22295	COG2610	gluconate transmembrane transporter activity
SG48_RS22300	COG0129	dihydroxy-acid dehydratase activity
SG48_RS22305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SG48_RS22310	COG1414	Transcriptional regulator
SG48_RS22315	COG1349	DNA-binding transcription factor activity
SG48_RS22320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SG48_RS22325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SG48_RS22330	COG0434	BtpA family
SG48_RS22335	COG3775	system Galactitol-specific IIC component
SG48_RS22340	COG3414	Phosphotransferase system galactitol-specific IIB component
SG48_RS22345	COG1363	Peptidase, m42
SG48_RS22350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SG48_RS22355	COG3153	acetyltransferase
SG48_RS22375	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SG48_RS22375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SG48_RS22385	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
SG48_RS22390	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SG48_RS22405	COG0582	viral genome integration into host DNA
SG48_RS22410	COG4974	Belongs to the 'phage' integrase family
SG48_RS22420	COG3539	Fimbrial protein
SG48_RS22425	COG3539	Fimbrial protein
SG48_RS22430	COG3121	Chaperone
SG48_RS22435	COG3188	usher protein
SG48_RS22440	COG3539	Fimbrial protein
SG48_RS22445	COG3539	Fimbrial protein
SG48_RS22450	COG3539	Fimbrial protein
SG48_RS22455	COG2610	gluconate transmembrane transporter activity
SG48_RS22470	COG0246	Mannitol dehydrogenase
SG48_RS22480	COG2186	Transcriptional regulator
SG48_RS22510	COG0583	DNA-binding transcription factor activity
SG48_RS22515	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SG48_RS22520	COG0700	Nucleoside recognition
SG48_RS22525	COG3366	ferrous iron transmembrane transporter activity
SG48_RS22535	COG0477	Major facilitator Superfamily
SG48_RS22540	COG3204	pilus organization
SG48_RS22550	COG1924	4 iron, 4 sulfur cluster binding
SG48_RS22555	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
SG48_RS22560	COG2733	membrane
SG48_RS22565	COG2814	Major facilitator Superfamily
SG48_RS22575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SG48_RS22580	COG5457	Domain of unknown function (DUF1127)
SG48_RS22585	COG1196	nuclear chromosome segregation
SG48_RS22595	COG4268	DNA restriction-modification system
SG48_RS22600	COG1401	restriction endodeoxyribonuclease activity
SG48_RS22610	COG0732	type I restriction modification DNA specificity domain
SG48_RS22615	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SG48_RS22620	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
SG48_RS22625	COG1715	Restriction endonuclease
SG48_RS22630	COG0523	cobalamin synthesis protein
SG48_RS22635	COG2879	small protein
SG48_RS22640	COG1966	Carbon starvation protein
SG48_RS22650	COG0840	transmembrane signaling receptor activity
SG48_RS22655	COG2271	Major facilitator Superfamily
SG48_RS22660	COG1802	Transcriptional regulator
SG48_RS22665	COG1063	alcohol dehydrogenase
SG48_RS22680	COG1484	DNA-dependent DNA replication
SG48_RS22695	COG2966	Psort location CytoplasmicMembrane, score
SG48_RS22700	COG2197	response regulator
SG48_RS22705	COG2197	response regulator
SG48_RS22710	COG4114	ferric iron reductase
SG48_RS22740	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
SG48_RS22745	COG0456	acetyltransferase
SG48_RS22750	COG1011	Hydrolase
SG48_RS22760	COG2823	Periplasmic or secreted lipoprotein
SG48_RS22770	COG4667	esterase of the alpha-beta hydrolase superfamily
SG48_RS22775	COG0084	hydrolase, TatD family'
SG48_RS22780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SG48_RS22785	COG1328	CTP reductase activity
SG48_RS22815	COG3550	peptidyl-serine autophosphorylation
SG48_RS22825	COG3726	membrane protein affecting hemolysin expression
SG48_RS22830	COG0560	Phosphoserine phosphatase
SG48_RS22835	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SG48_RS22840	COG3172	ATPase kinase involved in NAD metabolism
SG48_RS22840	COG1056	cytidyltransferase-related domain
SG48_RS22850	COG0488	(ABC) transporter
SG48_RS22855	COG0741	lytic transglycosylase activity
SG48_RS22875	COG2207	Transcriptional regulator
SG48_RS22875	COG3708	Transcriptional regulator
SG48_RS22880	COG3045	CreA protein
SG48_RS22885	COG0745	RESPONSE REGULATOR receiver
SG48_RS22890	COG2205	protein histidine kinase activity
SG48_RS22895	COG4452	Inner membrane protein CreD
SG48_RS22900	COG0745	RESPONSE REGULATOR receiver
SG48_RS22910	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA