locus_tag old_locus_tag gene Name start end strand product note type ID NCBI SG48_RS00005 SG48_0001 thrL thrL 190 255 + thr operon leader peptide involved in threonine biosynthesis%3B controls the expression of the thrLABC operon gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00005 SG48_RS00010 SG48_0002 thrA thrA 337 2799 + bifunctional aspartokinase/homoserine dehydrogenase 1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00010 SG48_RS00015 SG48_0003 SG48_RS00015 2801 3733 + homoserine kinase catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00015 SG48_RS00020 SG48_0004 SG48_RS00020 3734 5020 + threonine synthase gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00020 SG48_RS00025 SG48_RS00025 SG48_RS00025 5088 5237 + hypothetical protein gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00025 SG48_RS00030 SG48_0005 SG48_RS00030 5234 5530 + DUF2502 domain-containing protein gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00030 SG48_RS00035 SG48_0006 SG48_RS00035 5683 6459 - hypothetical protein gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00035 SG48_RS00040 SG48_0007 SG48_RS00040 6529 7959 - transporter gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00040 SG48_RS00045 SG48_0008 SG48_RS00045 8238 9191 + transaldolase 1 gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00045 SG48_RS00050 SG48_0009 mogA mogA 9306 9893 + molybdopterin adenylyltransferase forms a trimer%3B related to eukaryotic protein gephyrin%3B functions during molybdenum cofactor biosynthesis gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00050 SG48_RS00055 SG48_0010 SG48_RS00055 9928 10494 - succinate-acetate/proton symporter SatP gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00055 SG48_RS00060 SG48_0011 SG48_RS00060 10643 11356 - hypothetical protein gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00060 SG48_RS00065 SG48_0012 SG48_RS00065 11382 11786 - hypothetical protein gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00065 SG48_RS00070 SG48_0013 dnaK dnaK 12163 14079 + molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00070 SG48_RS00075 SG48_0014 SG48_RS00075 14168 15298 + molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00075 SG48_RS00080 SG48_0015 SG48_RS00080 15445 16557 + transposase gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00080 SG48_RS00085 SG48_0016 SG48_RS00085 16751 16903 - protein HokC gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00085 SG48_RS00090 SG48_0019 nhaA nhaA 17489 18655 + Na+/H+ antiporter NhaA exports sodium by using the electrochemical proton gradient to allow protons into the cell%3B functions in adaptation to high salinity and alkaline pH%3B activity increases at higher pH%3B downregulated at acidic pH gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00090 SG48_RS00095 SG48_0020 nhaR nhaR 18721 19620 + transcriptional regulator Na+/H+ antiporter regulatory protein%3B activates the genes nhaA and osmC gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00095 SG48_RS00100 SG48_0021 SG48_RS00100 19811 20314 - transposase gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00100 SG48_RS00105 SG48_0022 SG48_RS00105 20233 20508 - repressor TnpA gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00105 SG48_RS00110 SG48_0023 rpsT rpsT 20815 21078 - 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00110 SG48_RS00115 SG48_0024 SG48_RS00115 21181 21399 + hypothetical protein gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00115 SG48_RS00120 SG48_0025 SG48_RS00120 21407 22348 + bifunctional riboflavin kinase/FMN adenylyltransferase gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00120 SG48_RS00125 SG48_0026 ileS ileS 22391 25207 + isoleucine--tRNA ligase IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase family type 1 subfamily%3B some organisms carry two different copies of this enzyme gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00125 SG48_RS00130 SG48_0027 lspA lspA 25207 25701 + lipoprotein signal peptidase lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00130 SG48_RS00135 SG48_0028 SG48_RS00135 25826 26275 + peptidyl-prolyl cis-trans isomerase rotamase%3B accelerates isomerization of the peptidyl prolyl bond%2C involved in the folding of proteases gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00135 SG48_RS00140 SG48_0029 ispH ispH 26277 27227 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00140 SG48_RS00145 SG48_0030 SG48_RS00145 27293 28207 + non-specific ribonucleoside hydrolase RihC catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00145 SG48_RS00150 SG48_0031 SG48_RS00150 28374 29195 + 4-hydroxy-tetrahydrodipicolinate reductase catalyzes the reduction of 2%2C3-dihydrodipicolinate to 2%2C3%2C4%2C5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00150 SG48_RS00155 SG48_RS00155 SG48_RS00155 29237 29404 - hypothetical protein gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00155 SG48_RS00160 SG48_RS00160 SG48_RS00160 29438 29533 - hypothetical protein gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00160 SG48_RS00165 SG48_0032 SG48_RS00165 29651 30799 + carbamoyl-phosphate synthase small chain catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00165 SG48_RS00170 SG48_0033 carB carB 30817 34038 + carbamoyl-phosphate synthase large chain four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00170 SG48_RS00175 SG48_RS00175 SG48_RS00175 34086 34265 - hypothetical protein gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00175 SG48_RS00180 SG48_0034 SG48_RS00180 34300 34695 + transcriptional activatory protein CaiF regulator of carnitine metabolism%3B induces the caiTABCDE and fixABCX operons gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00180 SG48_RS00185 SG48_0035 SG48_RS00185 34781 35371 - carnitine operon protein CaiE involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00185 SG48_RS00190 SG48_0036 SG48_RS00190 35377 36162 - carnitinyl-CoA dehydratase catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00190 SG48_RS00195 SG48_0037 caiC caiC 36271 37824 - crotonobetaine/carnitine-CoA ligase gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00195 SG48_RS00200 SG48_0038 SG48_RS00200 37898 39115 - L-carnitine CoA-transferase catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA%2C also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00200 SG48_RS00205 SG48_0039 SG48_RS00205 39244 40386 - crotonobetainyl-CoA dehydrogenase catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00205 SG48_RS00210 SG48_0040 SG48_RS00210 40417 41931 - L-carnitine/gamma-butyrobetaine antiporter catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00210 SG48_RS00215 SG48_0041 SG48_RS00215 42403 43173 + protein FixA required for anaerobic carnitine reduction%2C may act to transfer electrons to crotonobetaine reductase gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00215 SG48_RS00220 SG48_0042 SG48_RS00220 43188 44129 + protein FixB gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00220 SG48_RS00225 SG48_0043 SG48_RS00225 44180 45466 + protein FixC FAD/NAD(P)-binding domain%3B possibly part of an electron transfer system required for anaerobic carnitine reduction gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00225 SG48_RS00230 SG48_0044 SG48_RS00230 45463 45750 + ferredoxin-like protein FixX gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00230 SG48_RS00235 SG48_0045 SG48_RS00235 45807 47138 + transporter gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00235 SG48_RS00240 SG48_0046 SG48_RS00240 47246 47776 + glutathione-regulated potassium-efflux system ancillary protein KefF Required for full activity of KefC%2C a potassium-proton antiporter gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00240 SG48_RS00245 SG48_0047 SG48_RS00245 47769 49631 + glutathione-regulated potassium-efflux system protein KefC transport system that facilitates potassium-efflux gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00245 SG48_RS00250 SG48_0048 folA folA 49823 50302 + dihydrofolate reductase catalyzes the reduction of dihydrofolate to tetrahydrofolate gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00250 SG48_RS00255 SG48_0049 apaH apaH 50380 51222 - diadenosine tetraphosphatase hydrolyzes P(1)%2CP(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00255 SG48_RS00260 SG48_0050 apaG apaG 51229 51606 - protein ApaG protein associated with Co2+ and Mg2+ efflux gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00260 SG48_RS00265 SG48_0051 ksgA ksgA 51609 52430 - ribosomal RNA small subunit methyltransferase A in Escherichia coli this enzyme catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA%3B mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin%3B members of this protein family have secondary functions gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00265 SG48_RS00270 SG48_0052 pdxA pdxA 52427 53416 - 4-hydroxythreonine-4-phosphate dehydrogenase catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00270 SG48_RS00275 SG48_0053 SG48_RS00275 53416 54702 - chaperone SurA Chaperone involved in the folding of extracytoplasmic proteins%2C especially OmpA%2C OmpF and LamB gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00275 SG48_RS00280 SG48_0054 SG48_RS00280 54755 57109 - LPS-assembly protein LptD is involved in outer membrane permeability gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00280 SG48_RS00285 SG48_0055 djlA djlA 57364 58179 + dnaJ-like protein DjlA functions as a co-chaperone with DnaK%3B involved in regulation of colanic acid capsule%3B inner membrane protein%3B dimerized via transmembrane domain%3B J-like domain is cytoplasmic and can functionally substitute for DnaJ%3B stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00285 SG48_RS00290 SG48_RS00290 SG48_RS00290 58474 59279 + UDP pyrophosphate phosphatase gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00290 SG48_RS00295 SG48_0057 SG48_RS00295 59687 60346 - ribosomal large subunit pseudouridine synthase A catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00295 SG48_RS00300 SG48_0058 SG48_RS00300 60358 63264 - RNA polymerase-associated protein RapA transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP%2C when it is trapped or immobilized on tightly supercoiled DNA gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00300 SG48_RS00305 SG48_0059 SG48_RS00305 63429 65780 - DNA polymerase II Has polymerase%2C DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00305 SG48_RS00310 SG48_0060 araD araD 65855 66550 - L-ribulose-5-phosphate 4-epimerase catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00310 SG48_RS00315 SG48_0061 SG48_RS00315 66835 68337 - L-arabinose isomerase catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00315 SG48_RS00320 SG48_0062 SG48_RS00320 68348 70048 - ribulokinase catalyzes the phosphorylation of ribulose to ribulose 5-phosphate gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00320 SG48_RS00325 SG48_0063 SG48_RS00325 70387 71265 + arabinose operon regulatory protein positive and negative regulator%3B regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00325 SG48_RS00330 SG48_0064 SG48_RS00330 71351 72115 + hypothetical protein gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00330 SG48_RS00335 SG48_0065 thiQ thiQ 72229 72927 - thiamine import ATP-binding protein ThiQ with TbpA and ThiP is part of the thiamine and TPP transport system gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00335 SG48_RS00340 SG48_0066 thiP thiP 72911 74521 - thiamine ABC transporter permease permease%3B with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell%3B repressed in presence of exogenous thiamine gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00340 SG48_RS00345 SG48_0067 tbpA tbpA 74497 75480 - thiamine-binding periplasmic protein part of the thiamine and TPP transport system tbpA-thiPQ gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00345 SG48_RS00350 SG48_0068 SG48_RS00350 75644 77299 - transcriptional regulator activates sgrS under glucose-phosphate stress conditions gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00350 SG48_RS00355 SG48_0070 SG48_RS00355 77388 77519 + inhibitor of glucose uptake gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00355 SG48_RS00360 SG48_0071 SG48_RS00360 77621 78799 + sugar efflux transporter A gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00360 SG48_RS00365 SG48_0072 leuD leuD 78848 79453 - 3-isopropylmalate dehydratase small subunit catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis%3B forms a heterodimer of LeuC/D gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00365 SG48_RS00370 SG48_0073 SG48_RS00370 79464 80864 - 3-isopropylmalate dehydratase large subunit dehydratase component%2C catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00370 SG48_RS00375 SG48_0074 SG48_RS00375 80867 81958 - 3-isopropylmalate dehydrogenase gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00375 SG48_RS00380 SG48_0075 SG48_RS00380 81958 83529 - 2-isopropylmalate synthase gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00380 SG48_RS00385 SG48_0076 SG48_RS00385 83622 83708 - leu operon leader peptide involved in attenuation control of the leuABCD operon in leucine biosynthesis gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00385 SG48_RS00390 SG48_0077 leuO leuO 84368 85312 + transcriptional regulator activator for leuABCD operon%3B member of LysR family of transcriptional activators gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00390 SG48_RS00395 SG48_0078 SG48_RS00395 85630 87354 + acetolactate synthase isozyme 3 large subunit catalyzes the formation of 2-acetolactate from pyruvate%2C leucine sensitive gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00395 SG48_RS00400 SG48_0079 ilvH ilvH 87357 87848 + acetolactate synthase isozyme 3 small subunit with IlvI catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase 3 small subunit gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00400 SG48_RS00405 SG48_RS00405 SG48_RS00405 87860 87946 + fruR/shl operon leader peptide gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00405 SG48_RS00410 SG48_0080 SG48_RS00410 88028 89032 + catabolite repressor/activator binds D-fructose as an inducer%3B involved in regulation of operons for central pathways of carbon metabolism gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00410 SG48_RS00415 SG48_0081 SG48_RS00415 89634 90092 + transcriptional regulator MraZ MraZ%3B UPF0040%3B crystal structure shows similarity to AbrB gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00415 SG48_RS00420 SG48_0082 SG48_RS00420 90094 91035 + ribosomal RNA small subunit methyltransferase H gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00420 SG48_RS00425 SG48_0083 SG48_RS00425 91032 91397 + cell division protein FtsL membrane bound cell division protein at septum containing leucine zipper motif gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00425 SG48_RS00430 SG48_0084 SG48_RS00430 91413 93179 + peptidoglycan synthase FtsI penicillin-binding protein 3%3B transpeptidase involved in septal peptidoglycan synthesis gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00430 SG48_RS00435 SG48_0085 murE murE 93166 94653 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2 6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00435 SG48_RS00440 SG48_0086 murF murF 94650 96008 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00440 SG48_RS00445 SG48_0087 mraY mraY 96002 97084 + phospho-N-acetylmuramoyl-pentapeptide transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00445 SG48_RS00450 SG48_0088 murD murD 97087 98403 + UDP-N-acetylmuramoylalanine--D-glutamate ligase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00450 SG48_RS00455 SG48_0089 SG48_RS00455 98403 99647 + lipid II flippase FtsW gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00455 SG48_RS00460 SG48_0090 murG murG 99644 100711 + UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase N-acetylglucosaminyl transferase%3B UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00460 SG48_RS00465 SG48_0091 SG48_RS00465 100765 102240 + UDP-N-acetylmuramate--L-alanine ligase gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00465 SG48_RS00470 SG48_0092 ddl ddl 102233 103153 + D-alanine--D-alanine ligase B D-alanine--D-alanine ligase%3B DdlA%3B DdlB%3B cytoplasmic%3B catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis%3B there are two forms of this enzyme in Escherichia coli gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00470 SG48_RS00475 SG48_0093 SG48_RS00475 103155 103985 + cell division protein FtsQ involved in septum formation gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00475 SG48_RS00480 SG48_0094 ftsA ftsA 103982 105244 + cell division protein FtsA ATP-binding involved in recruitment of FtsK to Z ring%3B essential cell division protein%3B colocalizes with FtsZ through direct interaction to the septal ring structure%3B structurally similar to eukaryotic actin%3B binds directly to the cell membrane gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00480 SG48_RS00485 SG48_0095 SG48_RS00485 105305 106456 + cell division protein FtsZ GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00485 SG48_RS00490 SG48_0096 lpxC lpxC 106557 107474 + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase zinc-dependent%3B catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00490 SG48_RS00495 SG48_0097 SG48_RS00495 107705 108217 + secretion monitor secM translational pause allows for the initiation of secA translation gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00495 SG48_RS00500 SG48_0098 secA secA 108279 110984 + protein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00500 SG48_RS00505 SG48_0099 SG48_RS00505 111044 111433 + 8-oxo-dGTP diphosphatase gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00505 SG48_RS00510 SG48_RS00510 SG48_RS00510 111564 111698 - hypothetical protein gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00510 SG48_RS00515 SG48_0100 SG48_RS00515 111649 111846 - DNA gyrase inhibitor YacG inhibits supercoiling by DNA gyrase by binding to the GyrB subunit gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00515 SG48_RS00520 SG48_0101 SG48_RS00520 111856 112599 - cell division protein ZapD gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00520 SG48_RS00525 SG48_0102 coaE coaE 112599 113219 - dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00525 SG48_RS00530 SG48_0103 SG48_RS00530 113444 114487 + GMP reductase catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00530 SG48_RS00535 SG48_0104 SG48_RS00535 114522 115724 - protein transport protein HofC gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00535 SG48_RS00540 SG48_0105 SG48_RS00540 115714 117099 - protein transport protein HofB gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00540 SG48_RS00545 SG48_0106 SG48_RS00545 117109 117549 - prepilin peptidase-dependent protein D gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00545 SG48_RS00550 SG48_RS00550 SG48_RS00550 117571 117795 + hypothetical protein gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00550 SG48_RS00555 SG48_0107 SG48_RS00555 117752 118645 - nicotinate-nucleotide pyrophosphorylase [carboxylating] catalyzes the formation of pyridine-2%2C3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00555 SG48_RS00560 SG48_0108 SG48_RS00560 118733 119284 + 1%2C6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00560 SG48_RS00565 SG48_0109 SG48_RS00565 119281 120135 + protein AmpE involved in regulation of beta-lactamase%3B putative signaling protein gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00565 SG48_RS00570 SG48_0110 SG48_RS00570 120178 121548 - aromatic amino acid transporter gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00570 SG48_RS00575 SG48_0111 pdhR pdhR 122092 122856 + pyruvate dehydrogenase complex repressor activates lctPRD operon%3B autoregulates itself through repression of pdhR-aceEF-lpdA operon%3B regulates pyruvate dehydrogenase complex gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00575 SG48_RS00580 SG48_0112 aceE aceE 123017 125680 + pyruvate dehydrogenase E1 component E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00580 SG48_RS00585 SG48_0113 aceF aceF 125695 127587 + dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex E2 component of pyruvate dehydrogenase multienzyme complex%3B in Escherichia coli AceF contains three N-terminal lipoyl domains gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00585 SG48_RS00590 SG48_0114 SG48_RS00590 127912 129336 + dihydrolipoyl dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00590 SG48_RS00595 SG48_0115 SG48_RS00595 129407 131260 - DUF3300 domain-containing protein gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00595 SG48_RS00600 SG48_0116 SG48_RS00600 131615 134212 + aconitate hydratase 2 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00600 SG48_RS00605 SG48_0117 SG48_RS00605 134388 134750 + hypothetical protein gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00605 SG48_RS00610 SG48_0118 SG48_RS00610 134788 135582 - S-adenosylmethionine decarboxylase proenzyme S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00610 SG48_RS00615 SG48_0119 SG48_RS00615 135598 136464 - polyamine aminopropyltransferase gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00615 SG48_RS00620 SG48_0120 SG48_RS00620 136570 136917 - PulS_OutS family protein gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00620 SG48_RS00625 SG48_0121 SG48_RS00625 137083 138633 + blue copper oxidase CueO laccase%3B copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00625 SG48_RS00630 SG48_0122 SG48_RS00630 138835 141225 - quinoprotein glucose dehydrogenase quinoprotein glucose dehydrogenase%3B catalyzes the formation of D-glucono-1%2C5-lactone from D-glucose and ubiquinone gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00630 SG48_RS00635 SG48_0123 SG48_RS00635 141431 141967 + hypoxanthine phosphoribosyltransferase catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00635 SG48_RS00640 SG48_0124 SG48_RS00640 142008 142670 - carbonic anhydrase catalyzes the interconversion of bicarbonate and carbon dioxide gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00640 SG48_RS00645 SG48_0125 SG48_RS00645 142779 143705 + ABC transporter ATPase gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00645 SG48_RS00650 SG48_0126 SG48_RS00650 143702 144472 + inner membrane transport permease YadH gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00650 SG48_RS00655 SG48_0127 SG48_RS00655 144577 145017 + PTS Enzyme IIA gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00655 SG48_RS00660 SG48_0128 SG48_RS00660 145081 146310 + polysaccharide deacetylase lipoprotein gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00660 SG48_RS00665 SG48_0129 SG48_RS00665 146314 146694 - aspartate 1-decarboxylase gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00665 SG48_RS00670 SG48_0130 SG48_RS00670 146968 147870 + transposase gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00670 SG48_RS00675 SG48_0131 panC panC 147944 148795 - pantothenate synthetase catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00675 SG48_RS00680 SG48_0132 panB panB 148807 149601 - 3-methyl-2-oxobutanoate hydroxymethyltransferase catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5%2C10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00680 SG48_RS00685 SG48_0133 SG48_RS00685 149715 150953 - fimbrial-like adhesin protein gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00685 SG48_RS00690 SG48_0134 SG48_RS00690 151003 151599 - fimbrial-like adhesin protein gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00690 SG48_RS00695 SG48_0135 SG48_RS00695 151626 152228 - fimbrial protein gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00695 SG48_RS00700 SG48_0136 SG48_RS00700 152243 152812 - fimbrial-like adhesin protein gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00700 SG48_RS00705 SG48_0137 SG48_RS00705 152829 155426 - outer membrane usher protein HtrE similar to the fimbrial usher protein PapC gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00705 SG48_RS00710 SG48_0138 ecpD ecpD 155461 156201 - fimbrial chaperone gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00710 SG48_RS00715 SG48_0139 SG48_RS00715 156299 156883 - fimbrial-like adhesin protein gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00715 SG48_RS00720 SG48_0140 SG48_RS00720 157253 157732 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine and ATP gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00720 SG48_RS00725 SG48_0141 pcnB pcnB 157729 159093 - poly(A) polymerase I Polymerase that creates the 3' poly(A) tail found in some mRNA's gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00725 SG48_RS00730 SG48_0142 SG48_RS00730 159186 160082 - glutamyl-Q tRNA(Asp) ligase this tRNA synthetase lacks the tRNA anticodon interaction domain%3B instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4%2C5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp%3B the modified tRNA does not bind elongation factor Tu gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00730 SG48_RS00735 SG48_0143 dksA dksA 160149 160604 - RNA polymerase-binding transcription factor DksA gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00735 SG48_RS00740 SG48_0144 SG48_RS00740 160782 161486 - sugar fermentation stimulation protein A gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00740 SG48_RS00745 SG48_0145 SG48_RS00745 161501 162031 - RNA 2'%2C3'-cyclic phosphodiesterase catalyzes the ligation and cleavage of of 2'-5' linkages in RNA gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00745 SG48_RS00750 SG48_0146 SG48_RS00750 162060 164534 + RNA helicase similar in sequence to the ATP-dependent RNA helicase HrpA gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00750 SG48_RS00755 SG48_RS00755 SG48_RS00755 164537 164743 + hypothetical protein gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00755 SG48_RS00760 SG48_0147 mrcB mrcB 164730 167264 + penicillin-binding protein 1B penicillin-binding protein 1b%3B contains transglycosylase and transpeptidase activity%3B major enzyme for peptidoglycan biosynthesis in Escherichia coli%3B transmembrane protein%3B forms dimers%3B three variants%2C one of which may be a degradation product%2C while the other appears to result from an alternative initiation site%2C are found within the cell gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00760 SG48_RS00765 SG48_0148 SG48_RS00765 167484 169727 + ferrichrome-iron receptor involved with the transport of ferrichrome across the outer membrane%3B binds the ferrichrome-iron ligand and interacts with the TonB protein gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00765 SG48_RS00770 SG48_0149 SG48_RS00770 169778 170575 + iron(3+)-hydroxamate import ATP-binding protein FhuC part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00770 SG48_RS00775 SG48_0150 SG48_RS00775 170575 171465 + iron(3+)-hydroxamate-binding protein FhuD Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter%3B binds to all hydroxamate siderophores gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00775 SG48_RS00780 SG48_0151 SG48_RS00780 171462 173444 + iron(3+)-hydroxamate import system permease FhuB gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00780 SG48_RS00785 SG48_0152 SG48_RS00785 173602 174882 - glutamate-1-semialdehyde 2%2C1-aminomutase Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00785 SG48_RS00790 SG48_0153 SG48_RS00790 175107 176528 + H+/Cl- exchange transporter ClcA Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00790 SG48_RS00795 SG48_0154 SG48_RS00795 176610 176954 + iron-sulfur cluster insertion protein ErpA essential respiratory protein A%3B may be involved in the transfer of iron-sulfur clusters%3B essential for growth using oxygen or alternate electron acceptors gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00795 SG48_RS00800 SG48_0155 SG48_RS00800 177001 177624 - hypothetical protein gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00800 SG48_RS00805 SG48_0156 SG48_RS00805 177662 178462 - vitamin B12-binding protein solute binding component of the vitamin B12 transport system BtuCDF gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00805 SG48_RS00810 SG48_0157 SG48_RS00810 178455 179153 - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00810 SG48_RS00815 SG48_0158 dgt dgt 179237 180754 + deoxyguanosinetriphosphate triphosphohydrolase forms a homotetramer%3B requires magnesium for activity%3B catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00815 SG48_RS00820 SG48_0159 SG48_RS00820 180884 182308 + periplasmic serine endoprotease DegP protease Do%3B required at high temperature%3B degrades damaged proteins gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00820 SG48_RS00825 SG48_0160 SG48_RS00825 182463 183620 + carbohydrate diacid regulator regulates the expression of the operons for the enzymes involved in galactarate%2C glucarate and glycerate utilization gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00825 SG48_RS00830 SG48_0161 SG48_RS00830 183709 184095 - hypothetical protein gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00830 SG48_RS00835 SG48_0162 SG48_RS00835 184257 185069 - phosphodiesterase YaeI gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00835 SG48_RS00840 SG48_0163 dapD dapD 185123 185947 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxylate N-succinyltransferase catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00840 SG48_RS00845 SG48_0164 SG48_RS00845 185978 188650 - uridylyltransferase catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00845 SG48_RS00850 SG48_0165 SG48_RS00850 188712 189506 - methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00850 SG48_RS00855 SG48_0167 SG48_RS00855 189874 190599 + 30S ribosomal protein S2 gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00855 SG48_RS00860 SG48_0168 tsf tsf 190857 191708 + elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00860 SG48_RS00865 SG48_0169 SG48_RS00865 191855 192580 + uridylate kinase gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00865 SG48_RS00870 SG48_0170 frr frr 192872 193429 + ribosome-recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00870 SG48_RS00875 SG48_0171 SG48_RS00875 193521 194717 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00875 SG48_RS00880 SG48_0172 SG48_RS00880 194906 195664 + UDP pyrophosphate synthase catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00880 SG48_RS00885 SG48_0173 cdsA cdsA 195677 196534 + phosphatidate cytidylyltransferase catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00885 SG48_RS00890 SG48_0174 SG48_RS00890 196546 197898 + inner membrane zinc RIP metalloprotease%3B RpoE activator%2C by degrading RseA%3B cleaved signal peptide endoprotease catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00890 SG48_RS00895 SG48_0175 SG48_RS00895 197928 200360 + outer membrane protein assembly factor BamA part of a complex with YfgL%2C YfiO%2C and NlpB involved in outer membrane protein biosynthesis%3B involved in the assembly of outer membrane proteins gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00895 SG48_RS00900 SG48_0176 SG48_RS00900 200482 200967 + chaperone protein Skp gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00900 SG48_RS00905 SG48_0177 lpxD lpxD 200971 201996 + UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00905 SG48_RS00910 SG48_0178 SG48_RS00910 202101 202556 + 3-hydroxyacyl-ACP dehydratase gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00910 SG48_RS00915 SG48_0179 SG48_RS00915 202560 203348 + acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00915 SG48_RS00920 SG48_0180 lpxB lpxB 203348 204496 + lipid-A-disaccharide synthase catalyzes the formation of lipid A disaccharide from UDP-2%2C3-diacylglucosamine and 2%2C3-diacylglucosamine-1-phosphate%2C lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00920 SG48_RS00925 SG48_0181 rnhB rnhB 204493 205089 + ribonuclease HII RNH2%3B RNase HII%3B binds manganese%3B endonuclease which specifically degrades the RNA of RNA-DNA hybrids gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00925 SG48_RS00930 SG48_0182 dnaE dnaE 205126 208608 + DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00930 SG48_RS00935 SG48_0183 SG48_RS00935 208621 209580 + acetyl-CoA carboxylase carboxyltransferase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00935 SG48_RS00940 SG48_0184 SG48_RS00940 209679 211820 + lysine decarboxylase constitutive constitutive%3B catalyzes the formation of cadaverine from lysine gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00940 SG48_RS00945 SG48_0185 SG48_RS00945 211877 212266 + lyase gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00945 SG48_RS00950 SG48_0186 tilS tilS 212331 213629 + tRNA(Ile)-lysidine synthase Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%3B ATP-dependent%3B responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00950 SG48_RS00955 SG48_0187 SG48_RS00955 213678 213938 - Rho-binding antiterminator Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00955 SG48_RS00960 SG48_0188 SG48_RS00960 213925 214125 - hypothetical protein gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00960 SG48_RS00965 SG48_0189 SG48_RS00965 214291 214836 + PDDEXK superfamily protein gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00965 SG48_RS00970 SG48_0190 SG48_RS00970 214833 215255 + peptidyl-tRNA hydrolase ArfB gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00970 SG48_RS00975 SG48_0191 SG48_RS00975 215269 215979 + lipoprotein NlpE gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00975 SG48_RS00980 SG48_0192 SG48_RS00980 216179 217003 - endopeptidase gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00980 SG48_RS00985 SG48_0193 SG48_RS00985 217057 218775 - proline--tRNA ligase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00985 SG48_RS00990 SG48_0194 SG48_RS00990 218887 219594 - tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00990 SG48_RS00995 SG48_0195 rcsF rcsF 219591 219995 - hypothetical protein gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS00995 SG48_RS01000 SG48_0196 metQ metQ 220113 220928 - D-methionine-binding lipoprotein MetQ gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01000 SG48_RS01005 SG48_0197 SG48_RS01005 220968 221621 - methionine ABC transporter part of the MetNIQ methionine uptake system gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01005 SG48_RS01010 SG48_0198 metN metN 221614 222645 - methionine import ATP-binding protein MetN part of the metNIQ transport system for methionine gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01010 SG48_RS01015 SG48_0199 SG48_RS01015 222833 223408 + D-glycero-beta-D-manno-heptose-1%2C7-bisphosphate 7-phosphatase Converts the D-glycero-beta-D-manno-heptose 1%2C7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01015 SG48_RS01020 SG48_0200 SG48_RS01020 223769 225324 + 16S ribosomal RNA rRNA gene203 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01020 SG48_RS01025 SG48_0201 SG48_RS01025 225381 225457 + tRNA-Ile tRNA gene204 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01025 SG48_RS01030 SG48_0202 SG48_RS01030 225500 225575 + tRNA-Ala tRNA gene205 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01030 SG48_RS01035 SG48_0203 SG48_RS01035 225750 228679 + 23S ribosomal RNA rRNA gene206 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01035 SG48_RS01040 SG48_0204 SG48_RS01040 228758 228873 + 5S ribosomal RNA rRNA gene207 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01040 SG48_RS01045 SG48_0205 SG48_RS01045 228928 229004 + tRNA-Asp tRNA gene208 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01045 SG48_RS01050 SG48_0206 dkgB dkgB 229167 229970 + 2%2C5-diketo-D-gluconic acid reductase B catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01050 SG48_RS01055 SG48_0207 SG48_RS01055 229967 230881 - LysR family transcriptional regulator gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01055 SG48_RS01060 SG48_0208 SG48_RS01060 231122 231922 + endo/exonuclease/phosphatase gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01060 SG48_RS01065 SG48_0209 SG48_RS01065 231926 232549 + S-adenosyl-L-methionine-dependent methyltransferase gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01065 SG48_RS01070 SG48_0210 mltD mltD 232597 233955 - murein transglycosylase catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues%3B may play a role in recycling muropeptides during cell division and/or cell elongation%3B in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01070 SG48_RS01075 SG48_0211 SG48_RS01075 234027 234782 - hydroxyacylglutathione hydrolase catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione%3B plays an important role in cellular detoxification using glutathione gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01075 SG48_RS01080 SG48_0212 SG48_RS01080 234816 235538 + S-adenosyl-L-methionine-dependent methyltransferase gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01080 SG48_RS01085 SG48_0213 SG48_RS01085 235535 236002 - ribonuclease HI%2C degrades RNA of DNA-RNA hybrids gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01085 SG48_RS01090 SG48_0214 SG48_RS01090 236058 236798 + DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01090 SG48_RS01095 SG48_0215 SG48_RS01095 236931 237007 + tRNA-Asp tRNA gene218 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01095 SG48_RS01100 SG48_0216 SG48_RS01100 237335 238120 + lipoprotein gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01100 SG48_RS01105 SG48_0217 SG48_RS01105 238257 238736 - hypothetical protein gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01105 SG48_RS01110 SG48_RS01110 SG48_RS01110 238746 239084 - hypothetical protein gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01110 SG48_RS01115 SG48_RS01115 SG48_RS01115 239136 239378 + transposase gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01115 SG48_RS01120 SG48_0220 SG48_RS01120 239419 240189 - hydrolase YafV NAD(P)-binding gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01120 SG48_RS01125 SG48_0221 SG48_RS01125 240370 240816 + hypothetical protein inactivates vertebrate C-type lysozyme gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01125 SG48_RS01130 SG48_0222 fadE fadE 240859 243303 - acyl-CoA dehydrogenase functions in fatty acid oxidation%3B converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01130 SG48_RS01135 SG48_0223 gmhA gmhA 243543 244121 + phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01135 SG48_RS01140 SG48_0224 SG48_RS01140 244327 245094 + glutamine amidotransferase gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01140 SG48_RS01145 SG48_0225 SG48_RS01145 245065 245805 - transpeptidase gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01145 SG48_RS01150 SG48_0226 SG48_RS01150 245961 246239 - mRNA interferase YafQ gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01150 SG48_RS01155 SG48_0227 SG48_RS01155 246242 246502 - antitoxin DinJ DNA-damage-inducible protein J%3B antitoxin of YafQ-DinJ toxin-antitoxin system gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01155 SG48_RS01160 SG48_0228 SG48_RS01160 246712 247461 + endopeptidase gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01160 SG48_RS01165 SG48_0229 SG48_RS01165 247637 248134 + transposase gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01165 SG48_RS01170 SG48_RS01170 SG48_RS01170 248358 250097 - flagellar biosynthesis protein FlhA gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01170 SG48_RS01175 SG48_RS01175 SG48_RS01175 250057 250827 + hypothetical protein gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01175 SG48_RS01180 SG48_0232 SG48_RS01180 250898 251953 + DNA polymerase IV involved in translesion DNA polymerization with beta clamp of polymerase III%3B belongs to Y family of polymerases%3B does not contain proofreading function gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01180 SG48_RS01185 SG48_0233 SG48_RS01185 252005 252298 + antitoxin YafN gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01185 SG48_RS01190 SG48_0234 SG48_RS01190 252301 252699 + mRNA interferase YafO YafO overproduction induces toxicity%3B it is believed to be the toxin of a toxin-antitoxin pair%3B unknown function gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01190 SG48_RS01195 SG48_0235 SG48_RS01195 252787 253161 + acyltransferase gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01195 SG48_RS01200 SG48_RS01200 SG48_RS01200 253467 253733 + hypothetical protein gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01200 SG48_RS01205 SG48_RS01205 prfH prfH 253645 254202 + peptide chain release factor similar to release factor 1 and 2 gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01205 SG48_RS01210 SG48_0238 SG48_RS01210 254259 255716 - cytosol non-specific dipeptidase catalyzes the hydrolysis of Xaa-His dipeptides gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01210 SG48_RS01215 SG48_0239 SG48_RS01215 255977 256435 + xanthine phosphoribosyltransferase catalyzes the conversion of guanine%2C xanthine and%2C to a lesser extent%2C hypoxanthine to GMP%2C XMP and IMP%2C respectively gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01215 SG48_RS01220 SG48_0240 frsA frsA 256527 257771 + esterase forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc%3B FrsA may promote fermentation gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01220 SG48_RS01225 SG48_0241 SG48_RS01225 257829 258230 + sigma factor-binding protein Crl involved in the expression of csgBA which is involved in curli formation%3B interacts with sigmaS gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01225 SG48_RS01230 SG48_0242 SG48_RS01230 258269 259324 - outer membrane pore protein E gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01230 SG48_RS01235 SG48_0243 SG48_RS01235 259612 260715 + glutamate 5-kinase gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01235 SG48_RS01240 SG48_0244 SG48_RS01240 260727 261980 + gamma-glutamyl phosphate reductase gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01240 SG48_RS01245 SG48_0245 SG48_RS01245 262095 262170 + tRNA-Thr tRNA gene248 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01245 SG48_RS01250 SG48_0247 SG48_RS01250 262552 262893 - toxin YkfI gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01250 SG48_RS01255 SG48_0248 SG48_RS01255 262914 263231 - antitoxin YafW gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01255 SG48_RS01260 SG48_0250 SG48_RS01260 263480 263956 - UPF0758 protein YkfG gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01260 SG48_RS01265 SG48_0251 SG48_RS01265 263972 264430 - hypothetical protein gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01265 SG48_RS01270 SG48_0252 SG48_RS01270 264528 264767 - UPF0401 protein YkfF gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01270 SG48_RS01275 SG48_0253 SG48_RS01275 264844 265311 - hypothetical protein gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01275 SG48_RS01280 SG48_0254 SG48_RS01280 265334 265777 - lipoprotein%2C inner membrane%3B degP regulator%3B CP4-6 prophage gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01280 SG48_RS01285 SG48_RS01285 SG48_RS01285 265777 266016 - membrane protein gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01285 SG48_RS01290 SG48_0257 SG48_RS01290 266408 267229 - UPF0380 protein YafZ gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01290 SG48_RS01295 SG48_0258 SG48_RS01295 267321 268184 - hypothetical protein gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01295 SG48_RS01300 SG48_0259 SG48_RS01300 268513 269406 - transcriptional regulator gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01300 SG48_RS01305 SG48_RS01305 SG48_RS01305 269502 269870 + transposase gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01305 SG48_RS01310 SG48_0261 SG48_RS01310 269827 270978 + transposase gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01310 SG48_RS01315 SG48_RS01315 SG48_RS01315 271054 271479 + DNA-binding protein gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01315 SG48_RS01320 SG48_RS01320 SG48_RS01320 271409 271777 - hypothetical protein gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01320 SG48_RS01325 SG48_RS01325 SG48_RS01325 271692 272117 - hypothetical protein gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01325 SG48_RS01330 SG48_RS01330 SG48_RS01330 272086 273215 + hypothetical protein gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01330 SG48_RS01335 SG48_0264 SG48_RS01335 273325 274305 - transposase gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01335 SG48_RS01340 SG48_0265 SG48_RS01340 274549 275952 + S-methylmethionine permease gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01340 SG48_RS01345 SG48_0266 SG48_RS01345 275939 276871 + homocysteine S-methyltransferase gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01345 SG48_RS01350 SG48_0267 fbpC fbpC 276980 278026 - Fe(3+) ions import ATP-binding protein FbpC Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01350 SG48_RS01355 SG48_RS01355 SG48_RS01355 278038 278400 - iron ABC transporter permease gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01355 SG48_RS01360 SG48_0269 SG48_RS01360 278402 278905 - transposase gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01360 SG48_RS01365 SG48_0270 SG48_RS01365 278824 279099 - repressor TnpA gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01365 SG48_RS01370 SG48_RS01370 SG48_RS01370 279248 279586 - transposase gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01370 SG48_RS01375 SG48_RS01375 SG48_RS01375 279609 279959 - hypothetical protein gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01375 SG48_RS01380 SG48_0273 SG48_RS01380 280053 281195 - hypothetical protein gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01380 SG48_RS01385 SG48_0274 SG48_RS01385 281502 282410 + hypothetical protein gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01385 SG48_RS01390 SG48_0275 SG48_RS01390 282425 284392 + hypothetical protein gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01390 SG48_RS01395 SG48_0276 SG48_RS01395 284619 286001 + hypothetical protein uncharacterized member of the GPH family of galactose-pentose-hexuronide transporters gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01395 SG48_RS01400 SG48_0277 SG48_RS01400 286013 287623 + arabinosidase gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01400 SG48_RS01405 SG48_0278 SG48_RS01405 287628 288386 - transcriptional regulator gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01405 SG48_RS01410 SG48_0279 SG48_RS01410 288525 289529 - ornithine carbamoyltransferase chain F catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01410 SG48_RS01415 SG48_0281 SG48_RS01415 289873 290376 - transposase gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01415 SG48_RS01420 SG48_RS01420 SG48_RS01420 290724 291455 + hypothetical protein gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01420 SG48_RS01425 SG48_0284 SG48_RS01425 291546 292172 - hypothetical protein gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01425 SG48_RS01430 SG48_0285 SG48_RS01430 292444 293142 - hypothetical protein gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01430 SG48_RS01435 SG48_0286 SG48_RS01435 293169 294023 - hypothetical protein gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01435 SG48_RS01440 SG48_RS01440 SG48_RS01440 294142 294366 - hypothetical protein gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01440 SG48_RS01445 SG48_0287 SG48_RS01445 294363 294803 - hypothetical protein gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01445 SG48_RS01450 SG48_0288 SG48_RS01450 294920 296245 - preprotein translocase gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01450 SG48_RS01455 SG48_RS01455 SG48_RS01455 296402 296478 + tRNA-Thr tRNA gene290 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01455 SG48_RS01460 SG48_RS01460 SG48_RS01460 296605 297015 - hypothetical protein gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01460 SG48_RS01465 SG48_0292 SG48_RS01465 296994 297950 - moco insertion factor for PaoABC aldehyde oxidoreductase gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01465 SG48_RS01470 SG48_0293 SG48_RS01470 297960 300158 - PaoABC aldehyde oxidoreductase Moco-containing subunit gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01470 SG48_RS01475 SG48_0294 SG48_RS01475 300155 301111 - PaoABC aldehyde oxidoreductase FAD-containing subunit gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01475 SG48_RS01480 SG48_0295 SG48_RS01480 301108 301797 - PaoABC aldehyde oxidoreductase 2Fe-2S subunit gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01480 SG48_RS01485 SG48_0296 SG48_RS01485 302215 302829 + hypothetical protein gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01485 SG48_RS01490 SG48_0297 SG48_RS01490 303077 303406 - ferredoxin gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01490 SG48_RS01495 SG48_0298 SG48_RS01495 303719 304429 - fimbrial chaperone EcpE gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01495 SG48_RS01500 SG48_0299 SG48_RS01500 304398 306041 - fimbria adhesin EcpD gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01500 SG48_RS01505 SG48_0300 SG48_RS01505 306031 308556 - usher protein EcpC gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01505 SG48_RS01510 SG48_0301 SG48_RS01510 308582 309250 - fimbrial chaperone EcpB gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01510 SG48_RS01515 SG48_0302 SG48_RS01515 309308 309895 - common pilus major fimbrillin subunit EcpA gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01515 SG48_RS01520 SG48_0303 SG48_RS01520 309970 310512 - LuxR family transcriptional regulator gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01520 SG48_RS01525 SG48_0304 SG48_RS01525 311336 311563 + hypothetical protein gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01525 SG48_RS01530 SG48_0305 rpmJ rpmJ 311598 311738 - 50S ribosomal protein L36 smallest protein in the large subunit%3B similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc%3B the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion%3B the proteins in this group do not have the motif gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01530 SG48_RS01535 SG48_0306 SG48_RS01535 311738 312001 - 50S ribosomal protein L31 type B gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01535 SG48_RS01540 SG48_0307 SG48_RS01540 312365 312466 - hypothetical protein gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01540 SG48_RS01545 SG48_RS01545 SG48_RS01545 313581 314468 + attachment protein gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01545 SG48_RS01550 SG48_0310 SG48_RS01550 314515 314814 + transposase gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01550 SG48_RS01555 SG48_0311 SG48_RS01555 314811 315677 + transposase gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01555 SG48_RS01560 SG48_RS01560 SG48_RS01560 315674 316360 - transcriptional regulator gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01560 SG48_RS01565 SG48_0314 SG48_RS01565 316950 317543 - protein RclC gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01565 SG48_RS01570 SG48_0315 SG48_RS01570 317555 317791 - reactive chlorine species (RCS) stress resistance periplasmic protein gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01570 SG48_RS01575 SG48_0316 SG48_RS01575 317900 319225 - pyridine nucleotide-disulfide oxidoreductase Involved in disulfide oxidoreductase activity and electron transport gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01575 SG48_RS01580 SG48_0317 SG48_RS01580 319451 320305 + transcriptional regulator gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01580 SG48_RS01585 SG48_0318 SG48_RS01585 320832 321551 + cysteine-rich LutA family protein%3B electron transport chain YkgEFG component gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01585 SG48_RS01590 SG48_0319 SG48_RS01590 321562 322989 + ferridoxin-like LutB family protein%3B electron transport chain YkgEFG component gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01590 SG48_RS01595 SG48_0320 SG48_RS01595 322982 323677 + LutC family protein%3B electron transport chain YkgEFG component gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01595 SG48_RS01600 SG48_RS01600 SG48_RS01600 323751 323873 - universal stress protein gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01600 SG48_RS01605 SG48_0321 SG48_RS01605 323920 324588 - hypothetical protein gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01605 SG48_RS01610 SG48_0322 SG48_RS01610 324801 326471 - oxygen-dependent choline dehydrogenase catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01610 SG48_RS01615 SG48_0323 SG48_RS01615 326485 327957 - NAD/NADP-dependent betaine aldehyde dehydrogenase gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01615 SG48_RS01620 SG48_0324 SG48_RS01620 327971 328558 - transcriptional regulator HTH-type%3B bet1%3B Repressor involved in choline regulation of the bet genes gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01620 SG48_RS01625 SG48_0325 SG48_RS01625 328687 330720 + choline transporter proton-motive-force-driven choline transporter gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01625 SG48_RS01630 SG48_RS01630 SG48_RS01630 331090 331275 - hypothetical protein gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01630 SG48_RS01635 SG48_0326 SG48_RS01635 331595 332683 + cyclic di-GMP phosphodiesterase YahA gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01635 SG48_RS01640 SG48_0327 SG48_RS01640 332725 333657 - DNA-bindng transcriptional regulator gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01640 SG48_RS01645 SG48_0328 SG48_RS01645 333749 334246 - hypothetical protein gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01645 SG48_RS01650 SG48_0329 SG48_RS01650 334504 335109 + transcriptional regulator gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01650 SG48_RS01655 SG48_0330 SG48_RS01655 335149 336012 + DUF2877 domain-containing protein gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01655 SG48_RS01660 SG48_0331 SG48_RS01660 336002 337549 + NAD(P)-binding succinyl-CoA synthase gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01660 SG48_RS01665 SG48_0332 SG48_RS01665 337549 338967 + DUF1116 domain-containing protein gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01665 SG48_RS01670 SG48_RS01670 SG48_RS01670 339017 339313 + hypothetical protein gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01670 SG48_RS01675 SG48_0333 SG48_RS01675 339389 340339 + carbamate kinase-like protein YahI gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01675 SG48_RS01680 SG48_0334 SG48_RS01680 340349 341731 + metallo-dependent hydrolase domain deaminase metallo-dependent hydrolase superfamily%3B deaminase with metallo-dependent hydrolase domain gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01680 SG48_RS01685 SG48_0335 SG48_RS01685 342108 343157 + aldehyde reductase YahK gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01685 SG48_RS01690 SG48_0336 SG48_RS01690 343400 344215 + hypothetical protein gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01690 SG48_RS01695 SG48_0337 SG48_RS01695 344628 344873 + hypothetical protein gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01695 SG48_RS01700 SG48_0338 SG48_RS01700 344890 345522 - membrane protein gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01700 SG48_RS01705 SG48_0339 SG48_RS01705 345708 345983 + periplasmic protein%2C function unknown%2C YhcN family gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01705 SG48_RS01710 SG48_0340 SG48_RS01710 346081 347667 - propionate catabolism operon regulatory protein PrpR sigma-54 dependent activator family protein%3B activates the prpBCDE operon gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01710 SG48_RS01715 SG48_0341 prpB prpB 347906 348796 + methylisocitrate lyase catalyzes the formation of pyruvate and succinate from 2-methylisocitrate gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01715 SG48_RS01720 SG48_0342 SG48_RS01720 349236 350405 + 2-methylcitrate synthase catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate%3B also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01720 SG48_RS01725 SG48_0343 prpD prpD 350439 351890 + 2-methylcitrate dehydratase functions in propionate metabolism%3B involved in isomerization of (2S%2C3S)-methylcitrate to (2R%2C3S)-methylisocitrate%3B also encodes minor aconitase or dehydratase activity%3B aconitase C gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01725 SG48_RS01730 SG48_0344 prpE prpE 351930 353816 + propionate--CoA ligase catalyzes the formation of propionyl-CoA using propionate as a substrate%3B PrpE from Ralstonia solanacearum can produce acetyl-%2C propionyl-%2C butyryl- and acrylyl-coenzyme A%2C and Salmonella enterica produces propionyl- and butyryl-coenzyme A%3B not expressed in Escherichia coli when grown on propionate/minimal media%3B ATP-dependent gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01730 SG48_RS01735 SG48_0345 codB codB 354146 355405 + cytosine permease gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01735 SG48_RS01740 SG48_0346 SG48_RS01740 355395 356678 + cytosine deaminase Catalyzes the deamination of cytosine to uracil and ammonia gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01740 SG48_RS01745 SG48_0347 SG48_RS01745 357015 357914 - transcriptional regulator controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01745 SG48_RS01750 SG48_0348 SG48_RS01750 358023 358682 + carbonic anhydrase gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01750 SG48_RS01755 SG48_0349 SG48_RS01755 358713 359183 + cyanate hydratase gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01755 SG48_RS01760 SG48_0350 cynX cynX 359189 360370 + MFS transporter MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon%3B not essential gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01760 SG48_RS01765 SG48_0351 lacA lacA 360473 361084 - galactoside O-acetyltransferase transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides%3B exact physiological role is unknown gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01765 SG48_RS01770 SG48_0352 lacY lacY 361150 362403 - lactose permease lactose/proton symporter%3B mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides%3B member of major facilitator superfamily%3B functions as a monomer with 12 transmembrane segments gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01770 SG48_RS01775 SG48_0353 lacZ lacZ 362455 365529 - beta-galactosidase forms a homotetramer%3B hydrolyzes lactose disaccharide to galactose and glucose%3B converts lactose to allolactose which is the natural inducer of the lac operon gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01775 SG48_RS01780 SG48_0354 lacI lacI 365652 366611 - lac repressor transcriptional repressor of lac operon%3B forms a homotetramer as a dimer of dimers%3B binds specific sites in lac operon resulting in DNA looping between the operators%3B binds allolactose as inducer gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01780 SG48_RS01785 SG48_0355 SG48_RS01785 366811 367644 - mhp operon transcriptional activator activator of 3-phenylpropionic acid catabolism gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01785 SG48_RS01790 SG48_0356 mhpA mhpA 367835 369499 + 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase catalyzes the formation of 3-(2%2C3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01790 SG48_RS01795 SG48_0357 mhpB mhpB 369501 370445 + 2%2C3-dihydroxyphenylpropionate/2%2C3-dihydroxicinnamic acid 1%2C2-dioxygenase catalyzes the cleavage of 3-(2%2C3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2%2C4-diene-1%2C9-dioate%3B part of the 3-phenylpropionic acid degradation pathway%3B member of the protocatechuate 4%2C5-dioxygenase family gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01795 SG48_RS01800 SG48_0358 SG48_RS01800 370463 371329 + 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01800 SG48_RS01805 SG48_0359 SG48_RS01805 371339 372148 + 2-keto-4-pentenoate hydratase gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01805 SG48_RS01810 SG48_0360 SG48_RS01810 372145 373095 + acetaldehyde dehydrogenase catalyzes the formation of acetyl-CoA from acetalaldehyde gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01810 SG48_RS01815 SG48_0361 SG48_RS01815 373092 374105 + 4-hydroxy-2-oxovalerate aldolase catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid%3B involved in the degradation of phenylpropionate gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01815 SG48_RS01820 SG48_0362 SG48_RS01820 374683 375894 + 3-(3-hydroxy-phenyl)propionate transporter gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01820 SG48_RS01825 SG48_0363 SG48_RS01825 375996 376535 + DUF2058 domain-containing protein gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01825 SG48_RS01830 SG48_0364 SG48_RS01830 376759 377592 - S-formylglutathione hydrolase FrmB gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01830 SG48_RS01835 SG48_0365 SG48_RS01835 377686 378795 - S-(hydroxymethyl)glutathione dehydrogenase catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione%3B also catalyzes the formation of aldehyde or ketone from alcohols gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01835 SG48_RS01840 SG48_0366 SG48_RS01840 378830 379105 - transcriptional regulator formaldehyde-induced negative regulator of the frmRAB operon gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01840 SG48_RS01845 SG48_0367 SG48_RS01845 379293 380066 - outer membrane protein gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01845 SG48_RS01850 SG48_RS01850 SG48_RS01850 380068 380511 - transferase gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01850 SG48_RS01855 SG48_RS01855 SG48_RS01855 380529 380618 - nitrite extrusion protein 2 gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01855 SG48_RS01860 SG48_0369 SG48_RS01860 380575 380940 + transposase represses IS2 gene transcription gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01860 SG48_RS01865 SG48_0370 SG48_RS01865 380898 381803 + integrase gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01865 SG48_RS01870 SG48_0371 SG48_RS01870 381963 383159 - family 2 glycosyltransferase gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01870 SG48_RS01875 SG48_0372 SG48_RS01875 383283 383840 - PIG-L family deacetylase gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01875 SG48_RS01880 SG48_0373 tauA tauA 384456 385418 + taurine-binding periplasmic protein with TauB and TauC is responsible for taurine uptake. gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01880 SG48_RS01885 SG48_0374 tauB tauB 385431 386198 + taurine import ATP-binding protein TauB Part of the ABC transporter complex tauABC involved in taurine import gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01885 SG48_RS01890 SG48_0375 SG48_RS01890 386195 387022 + taurine ABC transporter permease gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01890 SG48_RS01895 SG48_0376 tauD tauD 387019 387870 + alpha-ketoglutarate-dependent taurine dioxygenase catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide%3B non-heme iron oxidase%3B allows the use of taurine as an alternative sulfur source%3B forms homodimers gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01895 SG48_RS01900 SG48_0377 SG48_RS01900 387977 388951 - delta-aminolevulinic acid dehydratase gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01900 SG48_RS01905 SG48_RS01905 SG48_RS01905 389121 389372 - hypothetical protein gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01905 SG48_RS01910 SG48_RS01910 SG48_RS01910 389475 391001 + pertactin gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01910 SG48_RS01915 SG48_0379 SG48_RS01915 390963 391829 - transposase gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01915 SG48_RS01920 SG48_0380 SG48_RS01920 391826 392125 - transposase gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01920 SG48_RS01925 SG48_RS01925 SG48_RS01925 392200 393642 + pertactin gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01925 SG48_RS01930 SG48_0381 SG48_RS01930 393730 394353 + transcriptional regulator gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01930 SG48_RS01935 SG48_0382 SG48_RS01935 394354 395511 - D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH this protein has no known enzymatic function gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01935 SG48_RS01940 SG48_RS01940 SG48_RS01940 395649 395843 + hypothetical protein gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01940 SG48_RS01945 SG48_0383 SG48_RS01945 395863 397083 + peptide antibiotic transporter SbmA in Escherichia coli SbmA is involved in uptake of microcin J25%3B functions along with FhuA%2C TonB%2C and ExbB/D in this capacity%3B in Sinorhizobium meliloti%2C BacA is essential and required for symbiosis%3B defects appear to affect the cell envelope gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01945 SG48_RS01950 SG48_0384 SG48_RS01950 397096 398190 + microcin transporter gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01950 SG48_RS01955 SG48_0385 SG48_RS01955 398249 398557 - hypothetical protein gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01955 SG48_RS01960 SG48_0386 SG48_RS01960 398817 399029 + DUF2754 domain-containing protein gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01960 SG48_RS01965 SG48_0387 SG48_RS01965 399053 400147 - D-alanine--D-alanine ligase A gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01965 SG48_RS01970 SG48_RS01970 SG48_RS01970 400228 400428 + hypothetical protein gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01970 SG48_RS01975 SG48_0388 SG48_RS01975 400610 400870 + anti-adapter protein IraP RpoS stabilzer during Pi starvation%3B anti-adapter protein gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01975 SG48_RS01980 SG48_0389 SG48_RS01980 400971 402386 + alkaline phosphatase gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01980 SG48_RS01985 SG48_0390 SG48_RS01985 402505 402825 + phosphate starvation-inducible protein PsiF gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01985 SG48_RS01990 SG48_0391 adrA adrA 402927 404042 + diguanylate cyclase catalyzes the conversion of 2 GTP into c-di-GMP%3B adrA overexpression induces cellulose biosynthesis%2C cell adherence to abiotic surfaces and swimming and swarming motility%3B AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01990 SG48_RS01995 SG48_0392 SG48_RS01995 404059 404868 - pyrroline-5-carboxylate reductase catalyzes the formation of L-proline from pyrroline-5-carboxylate gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS01995 SG48_RS02000 SG48_0393 SG48_RS02000 404988 405446 + hypothetical protein gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02000 SG48_RS02005 SG48_0394 aroL aroL 405629 406153 + shikimate kinase type II enzyme similar to type I but differentially regulated and with a lower Km%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02005 SG48_RS02010 SG48_0395 SG48_RS02010 406203 406394 + hypothetical protein gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02010 SG48_RS02015 SG48_RS02015 SG48_RS02015 406425 406622 + hypothetical protein gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02015 SG48_RS02020 SG48_0396 SG48_RS02020 406652 407329 + protein AroM gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02020 SG48_RS02025 SG48_0397 SG48_RS02025 407401 407685 + hypothetical protein gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02025 SG48_RS02030 SG48_RS02030 SG48_RS02030 407893 408174 + hypothetical protein gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02030 SG48_RS02035 SG48_0399 SG48_RS02035 408332 409243 - recombination-associated protein RdgC Required for efficient pilin antigenic variation gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02035 SG48_RS02040 SG48_0400 SG48_RS02040 409368 410276 + fructokinase catalyzes phosphorylation of fructose%3B cytosolic enzyme gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02040 SG48_RS02045 SG48_0401 SG48_RS02045 410521 411705 - protein AraJ member of the major facilitator superfamily (MFS) of transporters%3B unknown function%3B may be associated with transport or processing of arabinose polymers gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02045 SG48_RS02050 SG48_0402 SG48_RS02050 411831 414977 - nuclease SbcCD subunit C with SbcD cleaves DNA hairpin structures%3B also has 5' single-strand endonuclease activity gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02050 SG48_RS02055 SG48_0403 SG48_RS02055 414974 416176 - nuclease SbcCD subunit D with SbcC cleaves DNA hairpin structure%2C also has 5' single-strand endonuclease activity gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02055 SG48_RS02060 SG48_0404 SG48_RS02060 416366 417055 + two-component system response regulator two component response regulator for the phosphate regulon%3B PhoR phosphorylates PhoB gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02060 SG48_RS02065 SG48_0405 phoR phoR 417113 418408 + phosphate regulon sensor protein PhoR membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02065 SG48_RS02070 SG48_0406 SG48_RS02070 418815 420134 + branched-chain amino acid transport system 2 carrier protein sodium:branched-chain amino acid symporter gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02070 SG48_RS02075 SG48_0407 proY proY 420210 421583 + proline-specific permease ProY cryptic permease that may be involved in the transport of proline across the inner membrane%3B in Salmonella typhimurium%2C the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02075 SG48_RS02080 SG48_0408 SG48_RS02080 421739 423556 + maltodextrin glucosidase gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02080 SG48_RS02085 SG48_0409 SG48_RS02085 423561 424142 - ACP phosphodiesterase Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02085 SG48_RS02090 SG48_0410 queA queA 424235 425305 + S-adenosylmethionine:tRNA ribosyltransferase-isomerase Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02090 SG48_RS02095 SG48_0411 tgt tgt 425361 426488 + queuine tRNA-ribosyltransferase Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr) gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02095 SG48_RS02100 SG48_0412 yajC yajC 426511 426843 + preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02100 SG48_RS02105 SG48_0413 secD secD 426871 428718 + preprotein translocase subunit SecD part of the preprotein secretory system%3B when complexed with proteins SecF and YajC%2C SecDFyajC stimulates the proton motive force-driven protein translocation%2C and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02105 SG48_RS02110 SG48_0414 SG48_RS02110 428729 429700 + protein translocase subunit SecF gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02110 SG48_RS02115 SG48_0415 SG48_RS02115 429829 430176 + hypothetical protein gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02115 SG48_RS02120 SG48_RS02120 SG48_RS02120 430190 430312 + hypothetical protein gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02120 SG48_RS02125 SG48_0416 SG48_RS02125 430353 431237 - nucleoside-specific channel-forming protein tsx receptor of phage T6 and colicin K%3B involved in the transfer of deoxyribo- and ribo-nucleotides across the outer membrane gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02125 SG48_RS02130 SG48_0417 SG48_RS02130 431536 432075 - lipoprotein gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02130 SG48_RS02135 SG48_0418 SG48_RS02135 432226 432675 + NrdR family transcriptional regulator gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02135 SG48_RS02140 SG48_0419 ribD ribD 432679 433782 + riboflavin biosynthesis protein RibD riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway%3B catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02140 SG48_RS02145 SG48_0420 ribH ribH 433871 434341 + 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02145 SG48_RS02150 SG48_0421 nusB nusB 434361 434780 + transcription antitermination protein NusB Regulates rRNA biosynthesis by transcriptional antitermination gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02150 SG48_RS02155 SG48_0422 SG48_RS02155 434858 435835 + thiamine-monophosphate kinase catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02155 SG48_RS02160 SG48_0423 SG48_RS02160 435813 436331 + phosphatidylglycerophosphatase A hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02160 SG48_RS02165 SG48_0424 SG48_RS02165 436385 437359 - 2-carboxybenzaldehyde reductase gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02165 SG48_RS02170 SG48_0425 SG48_RS02170 437539 439401 - 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02170 SG48_RS02175 SG48_0426 SG48_RS02175 439426 440325 - farnesyl-diphosphate synthase gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02175 SG48_RS02180 SG48_0427 SG48_RS02180 440325 440567 - exodeoxyribonuclease 7 small subunit catalyzes the bidirectional exonucleolytic cleavage of DNA gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02180 SG48_RS02185 SG48_0428 SG48_RS02185 440773 442221 + tRNA sulfurtransferase catalyzes the conversion of uridine to 4-thiouridinine tRNA%3B also required for the synthesis of the thiazole moiety gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02185 SG48_RS02190 SG48_0429 SG48_RS02190 442275 442865 - hypothetical protein gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02190 SG48_RS02195 SG48_0430 SG48_RS02195 442828 443739 - 2-dehydropantoate 2-reductase ketopantoate reductase%3B catalyzes the NADPH reduction of ketopantoate to pantoate%3B functions in pantothenate (vitamin B5) biosynthesis gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02195 SG48_RS02200 SG48_0431 SG48_RS02200 443907 444398 + nucleotide-binding protein nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ%3B the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02200 SG48_RS02205 SG48_0432 SG48_RS02205 444526 445890 - transporter gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02205 SG48_RS02210 SG48_0433 SG48_RS02210 446039 446929 - protoheme IX farnesyltransferase converts protoheme IX and farnesyl diphosphate to heme O gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02210 SG48_RS02215 SG48_0434 SG48_RS02215 446941 447270 - cytochrome bo(3) ubiquinol oxidase subunit 4 gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02215 SG48_RS02220 SG48_0435 SG48_RS02220 447270 447884 - cytochrome bo(3) ubiquinol oxidase subunit 3 gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02220 SG48_RS02225 SG48_0436 SG48_RS02225 447874 449865 - cytochrome bo(3) ubiquinol oxidase subunit 1 gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02225 SG48_RS02230 SG48_0437 SG48_RS02230 449887 450834 - cytochrome bo(3) ubiquinol oxidase subunit 2 gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02230 SG48_RS02235 SG48_0438 ampG ampG 451294 452769 - muropeptide MFS transporter AmpG in Escherichia coli this protein is a permease involved in peptidoglycan recycling%3B member of major facilitator superfamily%3B MFS%3B inner membrane protein gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02235 SG48_RS02240 SG48_0439 SG48_RS02240 452813 453391 - hypothetical protein gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02240 SG48_RS02245 SG48_0440 SG48_RS02245 453696 454013 + protein BolA positive transcriptional regulator of morphogenetic pathway%3B controlling several genes involved in oxidative stress%2C acid stress%2C heat shock%2C osmotic shock%2C and carbon-starvation stress gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02245 SG48_RS02250 SG48_RS02250 SG48_RS02250 454022 454210 + hypothetical protein gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02250 SG48_RS02255 SG48_0441 SG48_RS02255 454357 455655 + trigger factor gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02255 SG48_RS02260 SG48_0442 SG48_RS02260 455901 456524 + ATP-dependent Clp protease proteolytic subunit gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02260 SG48_RS02265 SG48_0443 clpX clpX 456650 457924 + ATP-dependent Clp protease ATP-binding subunit ClpX binds and unfolds substrates as part of the ClpXP protease gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02265 SG48_RS02270 SG48_0444 SG48_RS02270 458112 460466 + lon protease gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02270 SG48_RS02275 SG48_0445 SG48_RS02275 460675 460947 + DNA-binding protein HU-beta histone-like DNA-binding protein gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02275 SG48_RS02280 SG48_0446 SG48_RS02280 461139 463010 + peptidyl-prolyl cis-trans isomerase gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02280 SG48_RS02285 SG48_0447 SG48_RS02285 463161 463532 + hypothetical protein gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02285 SG48_RS02290 SG48_0448 SG48_RS02290 463626 464024 + long-chain acyl-CoA thioesterase FadM gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02290 SG48_RS02295 SG48_0449 SG48_RS02295 464076 464771 - 7-cyano-7-deazaguanine synthase YbaX%3B catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0)%2C as one of the early reactions of quenosine biosynthesis%3B quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn%2C Asp%2C Tyr%2C and His gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02295 SG48_RS02300 SG48_0450 SG48_RS02300 464836 466536 - ABC transporter substrate-binding protein gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02300 SG48_RS02305 SG48_0451 SG48_RS02305 466636 467454 + HMP-PP phosphatase HMP-PP phosphatase%3B catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02305 SG48_RS02310 SG48_0452 SG48_RS02310 467607 468065 + transcriptional regulator gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02310 SG48_RS02315 SG48_0453 SG48_RS02315 468095 469867 + multidrug resistance-like ATP-binding protein MdlA gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02315 SG48_RS02320 SG48_0454 SG48_RS02320 469860 471641 + multidrug resistance-like ATP-binding protein MdlB gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02320 SG48_RS02325 SG48_0455 SG48_RS02325 471822 472160 + nitrogen regulatory protein P-II 2 indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02325 SG48_RS02330 SG48_0456 SG48_RS02330 472190 473476 + ammonia channel gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02330 SG48_RS02335 SG48_0457 SG48_RS02335 473525 474385 - acyl-CoA thioesterase 2 gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02335 SG48_RS02340 SG48_0458 SG48_RS02340 474603 475175 + hypothetical protein gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02340 SG48_RS02345 SG48_RS02345 SG48_RS02345 475206 475517 - methylated-DNA--protein-cysteine methyltransferase gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02345 SG48_RS02350 SG48_0461 SG48_RS02350 475896 476249 + DUF1428 domain-containing protein gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02350 SG48_RS02355 SG48_0462 SG48_RS02355 476291 477841 - cyclic-di-GMP phosphodiesterase gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02355 SG48_RS02360 SG48_0463 SG48_RS02360 478005 478475 - hypothetical protein gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02360 SG48_RS02365 SG48_0464 SG48_RS02365 478591 479142 - maltose O-acetyltransferase gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02365 SG48_RS02370 SG48_0465 SG48_RS02370 479314 479532 - hemolysin expression-modulating protein Hha with Hns involved in transcriptional regulation of hemolysin%3B non-specific DNA-binding protein which affects the production of multiple proteins gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02370 SG48_RS02375 SG48_0466 SG48_RS02375 479558 479932 - Hha toxicity modulator TomB gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02375 SG48_RS02380 SG48_0467 SG48_RS02380 480478 483627 - multidrug efflux RND transporter permease subunit gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02380 SG48_RS02385 SG48_0468 SG48_RS02385 483650 484843 - MexE family multidrug efflux RND transporter periplasmic adaptor subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02385 SG48_RS02390 SG48_0469 SG48_RS02390 484985 485632 + transcriptional regulator regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02390 SG48_RS02395 SG48_0470 SG48_RS02395 485760 489122 + mechanosensitive channel MscK gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02395 SG48_RS02400 SG48_RS02400 SG48_RS02400 489160 489300 - hypothetical protein gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02400 SG48_RS02405 SG48_0471 SG48_RS02405 489334 489495 - DUF2496 domain-containing protein gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02405 SG48_RS02410 SG48_0472 SG48_RS02410 489509 490036 - primosomal replication protein N'' PriC%3B protein involved in DNA replication%3B part of the primosome%2C a protein complex required to restart stalled replication forks%3B binds the complex formed by PriA%2C PriB and DNA%3B PriC-dependent primosome requires a gap to restart DNA replication%3B stimulates Rep activity at stalled forks gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02410 SG48_RS02415 SG48_0473 SG48_RS02415 490106 490483 + hypothetical protein gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02415 SG48_RS02420 SG48_0474 SG48_RS02420 490636 491187 + adenine phosphoribosyltransferase catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02420 SG48_RS02425 SG48_0475 SG48_RS02425 491316 493247 + DNA polymerase III subunit tau catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the tau chain serves as a scaffold to help in the dimerizaton of the alpha%2Cepsilon and theta core complex%3B the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02425 SG48_RS02430 SG48_0476 SG48_RS02430 493300 493629 + nucleoid-associated protein gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02430 SG48_RS02435 SG48_0477 recR recR 493629 494234 + recombination protein RecR involved in a recombinational process of DNA repair%2C independent of the recBC complex gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02435 SG48_RS02440 SG48_0478 SG48_RS02440 494344 496218 + chaperone protein HtpG molecular chaperone gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02440 SG48_RS02445 SG48_0479 adk adk 496399 497043 + adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02445 SG48_RS02450 SG48_0480 SG48_RS02450 497279 498241 + ferrochelatase gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02450 SG48_RS02455 SG48_0481 SG48_RS02455 498238 499197 - acetyl esterase gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02455 SG48_RS02460 SG48_0482 SG48_RS02460 499349 500653 + inosine-guanosine kinase catalyzes the formation of inosine/guanosine monophosphate from inosine or guanosine and ATP gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02460 SG48_RS02465 SG48_0483 SG48_RS02465 500786 502462 - hypothetical protein YbaL%3B member of the CPA-2 family of antiporters%3B uncharacterized protein gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02465 SG48_RS02470 SG48_0484 SG48_RS02470 502700 503920 - fosmidomycin resistance protein gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02470 SG48_RS02475 SG48_0485 ushA ushA 504138 505790 + protein UshA catalyzes the degradation of periplasmic UDP-glucose to uridine%2C glucose-1-phosphate and inorganic phosphate%3B specific for uridine nucleotides gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02475 SG48_RS02480 SG48_0486 SG48_RS02480 505827 506306 - cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02480 SG48_RS02485 SG48_0488 SG48_RS02485 506510 507304 - TraB family protein gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02485 SG48_RS02490 SG48_0489 SG48_RS02490 507442 507783 + transcriptional regulator gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02490 SG48_RS02495 SG48_0490 copA copA 508099 510603 - copper-exporting P-type ATPase A gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02495 SG48_RS02500 SG48_0491 SG48_RS02500 510865 511797 + glutaminase 1 catalyzes the formation of glutamate from glutamine gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02500 SG48_RS02505 SG48_0492 SG48_RS02505 511800 513092 + transporter gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02505 SG48_RS02510 SG48_0493 SG48_RS02510 513217 513624 + transcriptional regulator activator of copper-responsive regulon genes gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02510 SG48_RS02515 SG48_0494 SG48_RS02515 513625 514083 - hypothetical protein gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02515 SG48_RS02520 SG48_0495 SG48_RS02520 514080 514997 - protein QmcA gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02520 SG48_RS02525 SG48_0496 SG48_RS02525 515143 515820 + iron export ATP-binding protein FetA gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02525 SG48_RS02530 SG48_0497 SG48_RS02530 515807 516586 + iron export permease FetB gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02530 SG48_RS02535 SG48_0498 SG48_RS02535 516649 517503 - molecular chaperone DnaK gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02535 SG48_RS02540 SG48_0499 SG48_RS02540 517564 518334 - oxidoreductase gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02540 SG48_RS02545 SG48_0500 SG48_RS02545 518363 518986 - multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02545 SG48_RS02550 SG48_0501 SG48_RS02550 518957 519643 + ABC transporter ATP-binding protein gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02550 SG48_RS02555 SG48_0502 SG48_RS02555 519640 522054 + ABC transporter permease gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02555 SG48_RS02560 SG48_0503 SG48_RS02560 522485 526765 + RHS element protein gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02560 SG48_RS02565 SG48_0504 SG48_RS02565 526805 527173 + immunity protein gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02565 SG48_RS02570 SG48_RS02570 SG48_RS02570 527173 527883 + hypothetical protein gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02570 SG48_RS02575 SG48_RS02575 SG48_RS02575 527864 528124 + hypothetical protein gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02575 SG48_RS02580 SG48_RS02580 SG48_RS02580 528869 529240 - hypothetical protein gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02580 SG48_RS02585 SG48_0509 SG48_RS02585 529356 530450 - tRNA 2-selenouridine synthase catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02585 SG48_RS02590 SG48_0510 SG48_RS02590 530519 531445 - HTH-type transcriptional activator AllS activator of the allDC-ylbA operon involved in allantoin utilization gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02590 SG48_RS02595 SG48_0511 SG48_RS02595 531675 532157 + ureidoglycolate lyase gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02595 SG48_RS02600 SG48_0512 SG48_RS02600 532235 533050 + transcriptional regulator regulates operons involved in the utilization of allantoin gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02600 SG48_RS02605 SG48_0513 SG48_RS02605 533140 534921 + glyoxylate carboligase catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02605 SG48_RS02610 SG48_0514 SG48_RS02610 534934 535710 + hydroxypyruvate isomerase gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02610 SG48_RS02615 SG48_0515 SG48_RS02615 535810 536688 + 2-hydroxy-3-oxopropionate reductase NADH-dependent%3B catalyzed the reversible formation of glycerate from tartronate semialdehyde gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02615 SG48_RS02620 SG48_0516 SG48_RS02620 536857 538311 + allantoin transporter gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02620 SG48_RS02625 SG48_0517 SG48_RS02625 538371 539732 + allantoinase Plays a crucial role on both purine and pyrimidine metabolism gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02625 SG48_RS02630 SG48_0518 SG48_RS02630 539789 541090 + uracil/xanthine transporter gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02630 SG48_RS02635 SG48_0519 SG48_RS02635 541112 542257 + glycerate kinase gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02635 SG48_RS02640 SG48_0520 SG48_RS02640 542485 543270 - (S)-ureidoglycine aminohydrolase gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02640 SG48_RS02645 SG48_0521 SG48_RS02645 543281 544516 - allantoate amidohydrolase gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02645 SG48_RS02650 SG48_0522 SG48_RS02650 544538 545587 - ureidoglycolate dehydrogenase (NAD+) catalyzes the formation of oxalurate from ureidoglycolate gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02650 SG48_RS02655 SG48_0523 SG48_RS02655 545904 547571 + protein FdrA multicopy suppressor of dominant negative ftsH mutations%3B putative acyl-CoA synthetase gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02655 SG48_RS02660 SG48_0524 SG48_RS02660 547581 548840 + DUF1116 domain-containing protein gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02660 SG48_RS02665 SG48_0525 SG48_RS02665 548851 549666 + anaerobic allantoin catabolic oxamate carbamoyltransferase%3B DUF2877 family protein gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02665 SG48_RS02670 SG48_0526 SG48_RS02670 549663 550556 + carbamate kinase reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02670 SG48_RS02675 SG48_0527 SG48_RS02675 550751 551818 - N5-carboxyaminoimidazole ribonucleotide synthase gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02675 SG48_RS02680 SG48_0528 purE purE 551815 552324 - N5-carboxyaminoimidazole ribonucleotide mutase catalyzes the formation of 4-carboxy-5-aminoimidazole ribonucleotide from N5-carboxyaminoimidazole ribonucleotide gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02680 SG48_RS02685 SG48_0529 SG48_RS02685 552442 553164 - UDP-2%2C3-diacylglucosamine hydrolase catalyzes the formation of 2%2C3%3Ddiacylglucosamine 1-phosphate from UDP-2%2C3%3Ddiacylglucosamine gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02685 SG48_RS02690 SG48_0530 SG48_RS02690 553167 553661 - peptidyl-prolyl cis-trans isomerase gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02690 SG48_RS02695 SG48_0531 cysS cysS 553835 555220 + cysteine--tRNA ligase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02695 SG48_RS02700 SG48_0532 SG48_RS02700 555256 555777 - hypothetical protein gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02700 SG48_RS02705 SG48_0533 SG48_RS02705 555885 556097 - ribosome-associated protein gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02705 SG48_RS02710 SG48_0534 SG48_RS02710 556099 556965 - bifunctional protein FolD gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02710 SG48_RS02715 SG48_0535 SG48_RS02715 557436 557978 + FimA homolog%2C function unknown gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02715 SG48_RS02720 SG48_0536 SG48_RS02720 558198 558890 + fimbrial chaperone SfmC gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02720 SG48_RS02725 SG48_0537 SG48_RS02725 558921 561524 + outer membrane usher protein SfmD gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02725 SG48_RS02730 SG48_0538 fimH fimH 561566 562543 + adhesin involved in the regulation of fimbriae length and mediates adhesion of type 1 fimbriae gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02730 SG48_RS02735 SG48_0539 SG48_RS02735 562554 563069 + FimA homolog%2C function unknown gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02735 SG48_RS02740 SG48_0540 SG48_RS02740 563072 563704 - fimbriae Z protein activates the production of the major fimbrae protein FimA gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02740 SG48_RS02745 SG48_0541 SG48_RS02745 563947 564023 + tRNA-Arg tRNA gene548 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02745 SG48_RS02750 SG48_0542 SG48_RS02750 564039 565202 - integrase gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02750 SG48_RS02755 SG48_RS02755 SG48_RS02755 565322 565585 - exonuclease gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02755 SG48_RS02760 SG48_RS02760 SG48_RS02760 565675 565911 + replication protein gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02760 SG48_RS02765 SG48_RS02765 SG48_RS02765 565908 566003 + hypothetical protein gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02765 SG48_RS02770 SG48_0547 SG48_RS02770 566066 566365 + transposase gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02770 SG48_RS02775 SG48_0548 SG48_RS02775 566362 567228 + transposase gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02775 SG48_RS02780 SG48_RS02780 SG48_RS02780 567259 567471 + protein ren gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02780 SG48_RS02785 SG48_0549 SG48_RS02785 567539 567871 + multidrug SMR transporter gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02785 SG48_RS02790 SG48_RS02790 SG48_RS02790 567919 568068 + membrane protein gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02790 SG48_RS02795 SG48_0550 SG48_RS02795 568126 569652 + DLP12 prophage%3B recombinase gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02795 SG48_RS02800 SG48_0551 SG48_RS02800 570117 570668 + hypothetical protein gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02800 SG48_RS02805 SG48_0552 SG48_RS02805 570678 571475 + transcriptional regulator gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02805 SG48_RS02810 SG48_0554 SG48_RS02810 571690 572145 + DLP12 prophage%3B uncharacterized protein DLP12 prophage gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02810 SG48_RS02815 SG48_0555 SG48_RS02815 572145 572315 + protein NinE from lambdoid prophage DLP12 DLP12 prophage%3B conserved protein similar to phage 82 and lambda proteins gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02815 SG48_RS02820 SG48_0556 SG48_RS02820 572308 572598 + DLP12 prophage%3B uncharacterized protein gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02820 SG48_RS02825 SG48_0557 SG48_RS02825 572595 572957 + crossover junction endodeoxyribonuclease RusA gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02825 SG48_RS02830 SG48_0558 SG48_RS02830 572954 573094 + protein%2C DLP12 prophage gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02830 SG48_RS02835 SG48_0559 SG48_RS02835 573180 573563 + Antitermination protein Q homolog from lambdoid prophage DLP12 gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02835 SG48_RS02840 SG48_RS02840 SG48_RS02840 573705 573923 + hypothetical protein gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02840 SG48_RS02845 SG48_0561 SG48_RS02845 573961 574941 - transposase gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02845 SG48_RS02850 SG48_RS02850 SG48_RS02850 574982 576049 - porin gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02850 SG48_RS02855 SG48_0562 SG48_RS02855 576622 576837 + Lysis protein S homolog from lambdoid prophage DLP12 gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02855 SG48_RS02860 SG48_0563 SG48_RS02860 576837 577334 + lysozyme RrrD gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02860 SG48_RS02865 SG48_0564 SG48_RS02865 577331 577792 + DLP12 prophage%3B murein endopeptidase gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02865 SG48_RS02870 SG48_0566 SG48_RS02870 577824 578117 - Lipoprotein bor homolog from lambdoid prophage DLP12 gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02870 SG48_RS02875 SG48_RS02875 SG48_RS02875 578268 578363 - hypothetical protein gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02875 SG48_RS02880 SG48_0567 SG48_RS02880 578408 578818 - DLP12 prophage%3B uncharacterized protein gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02880 SG48_RS02885 SG48_0568 SG48_RS02885 579104 579310 + DLP12 prophage%3B uncharacterized protein gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02885 SG48_RS02890 SG48_0569 SG48_RS02890 579475 579669 - DUF3950 domain-containing protein gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02890 SG48_RS02895 SG48_RS02895 SG48_RS02895 579817 579918 + DNA-packaging protein gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02895 SG48_RS02900 SG48_0570 SG48_RS02900 580058 580603 + DNA-packaging protein NU1 homolog gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02900 SG48_RS02905 SG48_RS02905 SG48_RS02905 580578 581321 + tail assembly protein gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02905 SG48_RS02910 SG48_RS02910 SG48_RS02910 581376 581807 - SAM-dependent methyltransferase gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02910 SG48_RS02915 SG48_RS02915 SG48_RS02915 582099 582359 + phage tail protein gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02915 SG48_RS02920 SG48_0575 SG48_RS02920 582905 583654 + transcriptional regulator gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02920 SG48_RS02925 SG48_0576 SG48_RS02925 583904 584857 - protease 7 gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02925 SG48_RS02930 SG48_RS02930 SG48_RS02930 585261 585377 - hypothetical protein gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02930 SG48_RS02935 SG48_0578 SG48_RS02935 585371 586132 - porin thermoregulatory protein EnvY involved in the thermoregulation of ompA%2C ompC%2C lamB and envelope proteins gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02935 SG48_RS02940 SG48_0579 SG48_RS02940 586315 587205 - PRK09936 family protein gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02940 SG48_RS02945 SG48_0580 SG48_RS02945 587206 590178 - bacteriophage N4 adsorption protein A gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02945 SG48_RS02950 SG48_0581 nfrB nfrB 590165 592402 - bacteriophage N4 adsorption protein B gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02950 SG48_RS02955 SG48_0582 SG48_RS02955 592552 593994 - two-component system sensor histidine kinase gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02955 SG48_RS02960 SG48_0583 SG48_RS02960 593984 594667 - two-component system response regulator response regulator in two-component regulatory system with CusS%3B regulates the copper efflux system gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02960 SG48_RS02965 SG48_0584 SG48_RS02965 594824 596197 + cation efflux system protein CusC with CusA%2C CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02965 SG48_RS02970 SG48_0585 SG48_RS02970 596355 596687 + cation efflux system protein CusF gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02970 SG48_RS02975 SG48_0586 SG48_RS02975 596703 597926 + cation efflux system protein CusB with CusA%2C CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02975 SG48_RS02980 SG48_0587 SG48_RS02980 597938 601081 + cation efflux system protein CusA gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02980 SG48_RS02985 SG48_0588 SG48_RS02985 601183 602559 + phenylalanine-specific permease gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02985 SG48_RS02990 SG48_0589 SG48_RS02990 602640 603887 - miniconductance mechanosensitive channel YbdG gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02990 SG48_RS02995 SG48_0590 SG48_RS02995 603995 604648 - oxygen-insensitive NAD(P)H nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrofurazone%2C quinones and the anti-tumor agent CB1954%3B NAD(P)H-dependent%3B oxygen insensitive gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS02995 SG48_RS03000 SG48_0591 SG48_RS03000 604742 605110 - DUF419 domain-containing protein gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03000 SG48_RS03005 SG48_0592 SG48_RS03005 605175 605423 - DUF1158 domain-containing protein gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03005 SG48_RS03010 SG48_0593 SG48_RS03010 605489 606607 - weak gamma-glutamyl:cysteine ligase gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03010 SG48_RS03015 SG48_RS03015 SG48_RS03015 606619 606768 + hypothetical protein gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03015 SG48_RS03020 SG48_0595 SG48_RS03020 607060 607212 + protein HokE gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03020 SG48_RS03025 SG48_0596 SG48_RS03025 607289 608401 + transposase gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03025 SG48_RS03030 SG48_0597 SG48_RS03030 608683 609312 - 4'-phosphopantetheinyl transferase gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03030 SG48_RS03035 SG48_0598 SG48_RS03035 609478 611718 - ferrienterobactin receptor Fep%3B Cbt%3B Cbr%3B FeuB%3B FepA%3B PfeA%3B IroN%3B BfeA%3B outer membrane receptor of ferric enterobactin and colicins B and D%3B interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03035 SG48_RS03040 SG48_0599 SG48_RS03040 611961 613163 + enterochelin esterase gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03040 SG48_RS03045 SG48_0600 SG48_RS03045 613166 613384 + enterobactin biosynthesis protein YbdZ gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03045 SG48_RS03050 SG48_0601 entF entF 613381 617262 + enterobactin synthase component F with EntB%2C EntD%2C and EntE forms the multienzyme complex enterobactin synthase%3B EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03050 SG48_RS03055 SG48_0602 SG48_RS03055 617478 618611 + ferric enterobactin transporter FepE in Salmonella is responsible for long O-antigen polymerization%3B may be part of the ferric enterobactin transport system%3B necessary for enetrobactin uptake gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03055 SG48_RS03060 SG48_0603 SG48_RS03060 618608 619423 - ferric enterobactin transport ATP-binding protein FepC with FepBDE is involved in the transport of ferric enterobactin gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03060 SG48_RS03065 SG48_0604 SG48_RS03065 619420 620412 - ferric anguibactin ABC transporter permease with FepBCD is involved in the transport of ferric enterobactin gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03065 SG48_RS03070 SG48_0605 SG48_RS03070 620409 621413 - ferric anguibactin ABC transporter permease with FepBCG is involved in the transport of ferric enterobactin gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03070 SG48_RS03075 SG48_0606 SG48_RS03075 621524 622774 + enterobactin exporter EntS protein p43%3B inner membrane protein that exports enterobactin to the periplasmic space%3B member of the major facilitator superfamily (MFS) of transporters gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03075 SG48_RS03080 SG48_0607 SG48_RS03080 622778 623734 - ferrienterobactin-binding periplasmic protein with FepCDG is involved in the transport of ferric enterobactin gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03080 SG48_RS03085 SG48_0608 SG48_RS03085 624109 625284 + isochorismate synthase EntC gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03085 SG48_RS03090 SG48_0609 entE entE 625294 626904 + enterobactin synthase component E bifunctional 2%2C3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase%3B activates the carboxylate group of 2%2C3-dihydroxy-benzoate forming (2%2C3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2%2C3-dihydroxy-benzoate adenylate gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03090 SG48_RS03095 SG48_0610 SG48_RS03095 626918 627775 + enterobactin synthase component B 2%2C3 dihydro-2%2C3 dihydroxybenzoate synthase%3B catalyzes the formation of 2%2C3 dihydro-2%2C3 dihydroxybenzoate and pyruvate from isochorismate%3B with Ent DEF is involved in enterobactin synthesis gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03095 SG48_RS03100 SG48_0611 SG48_RS03100 627775 628521 + 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase catalyzes the formation of 2%2C3-dihydroxybenzoate from 2%2C3-dihydro-2%2C3-dihydroxybenzoate%3B involved in the biosynthesis of siderophores%2C enterobactin%2C bacillibactin or vibriobactin gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03100 SG48_RS03105 SG48_0612 SG48_RS03105 628524 628937 + proofreading thioesterase EntH required for efficient enterobactin production gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03105 SG48_RS03110 SG48_0613 SG48_RS03110 629118 631223 + carbon starvation protein A gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03110 SG48_RS03115 SG48_0614 SG48_RS03115 631406 631603 + hypothetical protein gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03115 SG48_RS03120 SG48_0615 SG48_RS03120 631613 632701 - oxidoreductase member of the iron-containing alcohol dehydrogenase family gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03120 SG48_RS03125 SG48_0616 SG48_RS03125 632810 633970 + methionine aminotransferase catalyzes the transfer of an amino moiety%3B preference for methionine followed by histidine and phenylalanine gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03125 SG48_RS03130 SG48_0617 SG48_RS03130 633971 634588 - hypothetical protein gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03130 SG48_RS03135 SG48_0618 SG48_RS03135 634573 635793 - PAPS reductase-like domain protein gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03135 SG48_RS03140 SG48_0619 SG48_RS03140 635940 636842 - transcriptional regulator gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03140 SG48_RS03145 SG48_0620 dsbG dsbG 637051 637797 - thiol:disulfide interchange protein DsbG Involved in disulfide bond formation gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03145 SG48_RS03150 SG48_0621 SG48_RS03150 638169 638732 + alkyl hydroperoxide reductase subunit C with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols%3B AhpC reduced the hydroperoxide substrate gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03150 SG48_RS03155 SG48_0622 SG48_RS03155 638977 640542 + alkyl hydroperoxide reductase subunit F gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03155 SG48_RS03160 SG48_0623 SG48_RS03160 640663 641091 - universal stress protein G interacts with GroEL%3B is induced by starvation%2C heat shock and toxic agents gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03160 SG48_RS03165 SG48_0624 SG48_RS03165 641312 642550 + Zn-dependent NAD(P)-binding oxidoreductase gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03165 SG48_RS03170 SG48_RS03170 SG48_RS03170 642554 642742 - hypothetical protein gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03170 SG48_RS03175 SG48_0625 SG48_RS03175 642781 643191 - nucleoside diphosphate kinase regulator Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis%2C CTP for lipid synthesis%2C and GTP for protein elongation gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03175 SG48_RS03180 SG48_0626 SG48_RS03180 643421 644227 - ribonuclease I gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03180 SG48_RS03185 SG48_0627 SG48_RS03185 644341 645804 - citrate carrier involved in the transport of citrate into the cell along with the export of succinate out of the cell gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03185 SG48_RS03190 SG48_0628 citG citG 645855 646733 - 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03190 SG48_RS03195 SG48_0629 citX citX 646708 647259 - apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase%3B holo-citrate lyase synthase%3B CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03195 SG48_RS03200 SG48_0630 SG48_RS03200 647263 648795 - citrate lyase alpha chain citrate-ACP transferase%2C the alpha subunit catalyzes the formation of (3S)-citryl-CoA from acetyl-CoA and citrate gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03200 SG48_RS03205 SG48_0631 SG48_RS03205 648806 649714 - citrate lyase subunit beta citryl-ACP lyase%3B catalyzes the formation of acetate and oxaloacetate from citrate gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03205 SG48_RS03210 SG48_0632 SG48_RS03210 649711 650007 - citrate lyase ACP gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03210 SG48_RS03215 SG48_0633 SG48_RS03215 650022 651080 - [Citrate [pro-3S]-lyase] ligase activates citrate lyase by acetylation of the gamma subunit gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03215 SG48_RS03220 SG48_0634 dpiB dpiB 651459 653117 + sensor histidine kinase regulates the expression of citrate fermentation genes gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03220 SG48_RS03225 SG48_0635 dpiA dpiA 653086 653766 + transcriptional regulator regulates the expression of citrate fermentation genes gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03225 SG48_RS03230 SG48_0636 dcuC dcuC 653807 655192 - anaerobic C4-dicarboxylate transporter DcuC responsible for the transport of C4-dicarboxylates during anaerobic growth gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03230 SG48_RS03235 SG48_0637 pagP pagP 655781 656341 + lipid A palmitoyltransferase PagP catalyzes the transfer of palmitate to lipid A gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03235 SG48_RS03240 SG48_0638 SG48_RS03240 656516 656725 + cold-shock protein CspE gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03240 SG48_RS03245 SG48_0639 SG48_RS03245 656779 657162 - fluoride efflux channel%2C dual topology membrane protein camphor resistance protein CrcB%3B may be involved in chromosome condensation%3B overexpression in Escherichia coli protects against decondensation by camphor%3B overexpressing the protein results in an increase in supercoiling gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03245 SG48_RS03250 SG48_RS03250 SG48_RS03250 657255 658042 + hydrolase gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03250 SG48_RS03255 SG48_0641 tatE tatE 658171 658374 + preprotein translocase subunit TatE TatE%3B similar to TatA and found in some proteobacteria%3B part of system that translocates proteins with a conserved twin arginine motif across the inner membrane%3B capable of translocating folded substrates typically those with bound cofactors%3B similar to a protein import system in thylakoid membranes gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03255 SG48_RS03260 SG48_0642 SG48_RS03260 658475 659440 - lipoyl synthase catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03260 SG48_RS03265 SG48_0643 SG48_RS03265 659649 660602 - LysR family transcriptional regulator gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03265 SG48_RS03270 SG48_RS03270 SG48_RS03270 660660 660809 + hypothetical protein gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03270 SG48_RS03275 SG48_0644 SG48_RS03275 660861 661502 - octanoyltransferase lipoyl/octanoyltransferase%3B catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03275 SG48_RS03280 SG48_0645 SG48_RS03280 661603 661866 - hypothetical protein gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03280 SG48_RS03285 SG48_0646 SG48_RS03285 661976 663187 - D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 5%3B removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03285 SG48_RS03290 SG48_0647 SG48_RS03290 663326 664414 - hypothetical protein septal ring protein%2C suppressor of prc%2C minor lipoprotein gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03290 SG48_RS03295 SG48_0648 SG48_RS03295 664425 665537 - rod shape-determining protein RodA gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03295 SG48_RS03300 SG48_0649 SG48_RS03300 665540 667441 - penicillin-binding protein 2 gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03300 SG48_RS03305 SG48_0650 SG48_RS03305 667472 667939 - ribosomal RNA large subunit methyltransferase H gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03305 SG48_RS03310 SG48_0651 SG48_RS03310 667943 668260 - ribosome silencing factor RsfS gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03310 SG48_RS03315 SG48_0652 SG48_RS03315 668520 669131 - adenosylcobalamin/alpha-ribazole phosphatase gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03315 SG48_RS03320 SG48_0653 SG48_RS03320 669155 669796 - nicotinate-nucleotide adenylyltransferase gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03320 SG48_RS03325 SG48_0654 holA holA 669798 670829 - DNA polymerase III subunit delta required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03325 SG48_RS03330 SG48_0655 SG48_RS03330 670829 671410 - hypothetical protein rare lipoprotein B%3B involved in the assembly of LPS in the outer membrane gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03330 SG48_RS03335 SG48_0656 leuS leuS 671425 674007 - leucine--tRNA ligase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03335 SG48_RS03340 SG48_0657 SG48_RS03340 674242 674724 + hypothetical protein gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03340 SG48_RS03345 SG48_0658 SG48_RS03345 674794 675771 - hypothetical protein gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03345 SG48_RS03350 SG48_0659 SG48_RS03350 675935 676642 + hypothetical protein gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03350 SG48_RS03355 SG48_0660 SG48_RS03355 676639 678066 + HscC co-chaperone%2C uncharacterized J domain-containing protein gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03355 SG48_RS03360 SG48_0661 SG48_RS03360 678076 678630 - hypothetical protein gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03360 SG48_RS03365 SG48_0662 SG48_RS03365 678732 679439 + DUF1266 domain-containing protein gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03365 SG48_RS03370 SG48_0663 SG48_RS03370 679436 680887 + J domain-containing HscC co-chaperone%3B Hsc56 gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03370 SG48_RS03375 SG48_0664 SG48_RS03375 680947 682617 - chaperone protein HscC gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03375 SG48_RS03380 SG48_0665 rihA rihA 682701 683636 - pyrimidine-specific ribonucleoside hydrolase RihA Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil%2C respectively%3B pyrimidine-specific gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03380 SG48_RS03385 SG48_0666 artP artP 683754 684479 - glutamate/aspartate transport ATP-binding protein GltL With ArtMQJI transports arginine across the inner membrane gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03385 SG48_RS03390 SG48_0667 SG48_RS03390 684479 685153 - glutamate ABC transporter permease with GltJLPS and GadC for glutamate and GltJLP%2C DctA and DcuAB for aspartate is involved in the transport of glutamate and aspartate gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03390 SG48_RS03395 SG48_0668 SG48_RS03395 685153 685893 - glutamate ABC transporter permease with GltIKL is involved in the transport of glutamate and aspartate gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03395 SG48_RS03400 SG48_0669 SG48_RS03400 686063 686971 - glutamate/aspartate periplasmic-binding protein gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03400 SG48_RS03405 SG48_0670 SG48_RS03405 687221 688201 - transposase gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03405 SG48_RS03410 SG48_0671 lnt lnt 688567 690105 - apolipoprotein N-acyltransferase Transfers the fatty acyl group on membrane lipoproteins gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03410 SG48_RS03415 SG48_0672 SG48_RS03415 690130 691008 - magnesium and cobalt efflux protein CorC involved in the transport of magnesium and cobalt ions gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03415 SG48_RS03420 SG48_0673 SG48_RS03420 691098 691565 - endoribonuclease YbeY gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03420 SG48_RS03425 SG48_0674 SG48_RS03425 691562 692602 - phoH-like protein gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03425 SG48_RS03430 SG48_0675 SG48_RS03430 692755 694179 - tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03430 SG48_RS03435 SG48_0676 ubiF ubiF 694325 695500 + 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol hydroxylase catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1%2C4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol%3B functions in the biosynthesis of ubiquinone or coenzyme Q gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03435 SG48_RS03440 SG48_0677 SG48_RS03440 695654 695728 - tRNA-Gln tRNA gene687 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03440 SG48_RS03445 SG48_0678 SG48_RS03445 695766 695840 - tRNA-Gln tRNA gene688 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03445 SG48_RS03450 SG48_0679 SG48_RS03450 695888 695964 - tRNA-Met tRNA gene689 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03450 SG48_RS03455 SG48_0680 SG48_RS03455 695980 696054 - tRNA-Gln tRNA gene690 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03455 SG48_RS03460 SG48_0681 SG48_RS03460 696089 696163 - tRNA-Gln tRNA gene691 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03460 SG48_RS03465 SG48_0682 SG48_RS03465 696187 696271 - tRNA-Leu tRNA gene692 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03465 SG48_RS03470 SG48_0683 SG48_RS03470 696281 696357 - tRNA-Met tRNA gene693 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03470 SG48_RS03475 SG48_0684 asnB asnB 696737 698401 - asparagine synthetase B [glutamine-hydrolyzing] functions in asparagine biosynthesis%3B converts glutamine%2C aspartate%2C ATP%2C and water to glutamate%2C asparagine%2C pyrophosphate and AMP gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03475 SG48_RS03480 SG48_0685 SG48_RS03480 698798 699550 - ribonucleotide monophosphatase NagD gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03480 SG48_RS03485 SG48_0686 SG48_RS03485 699598 700818 - N-acetylglucosamine repressor regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03485 SG48_RS03490 SG48_0687 nagA nagA 700827 701975 - N-acetylglucosamine-6-phosphate deacetylase catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03490 SG48_RS03495 SG48_0688 nagB nagB 702035 702835 - glucosamine-6-phosphate deaminase catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03495 SG48_RS03500 SG48_0689 SG48_RS03500 703168 705114 + PTS N-acetylglucosamine EIICBA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03500 SG48_RS03505 SG48_0690 SG48_RS03505 705317 706981 + glutamine--tRNA ligase catalyzes a two-step reaction%2C first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03505 SG48_RS03510 SG48_0691 chiP chiP 707558 708964 + chitoporin outer membrane porin involved in the transport of chitooligosaccharides gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03510 SG48_RS03515 SG48_0692 SG48_RS03515 709014 709340 + chitosugar-induced verified lipoprotein gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03515 SG48_RS03520 SG48_0693 fur fur 709424 709870 - ferric uptake regulation protein negatively regulates a number of operons that encode enzymes involved in iron transport%3B activated by manganese%3B forms a homodimer gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03520 SG48_RS03525 SG48_0694 SG48_RS03525 709863 709949 - Fur leader peptide gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03525 SG48_RS03530 SG48_RS03530 SG48_RS03530 709915 710169 + hypothetical protein gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03530 SG48_RS03535 SG48_0695 SG48_RS03535 710159 710689 - flavodoxin-1 An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03535 SG48_RS03540 SG48_0696 SG48_RS03540 710829 711122 - LexA-regulated protein%2C CopB family gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03540 SG48_RS03545 SG48_0697 SG48_RS03545 711262 712026 - esterase gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03545 SG48_RS03550 SG48_0698 SG48_RS03550 712211 712756 + negative modulator of initiation of replication negative modulator of the initiation of chromosome replication gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03550 SG48_RS03555 SG48_0699 SG48_RS03555 712782 714422 + phosphoglucomutase catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03555 SG48_RS03560 SG48_0700 SG48_RS03560 714636 715130 + lipoprotein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03560 SG48_RS03565 SG48_RS03565 SG48_RS03565 715171 715821 - hypothetical protein gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03565 SG48_RS03570 SG48_RS03570 SG48_RS03570 715945 716142 - hypothetical protein gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03570 SG48_RS03575 SG48_0703 potE potE 716170 717489 - putrescine-ornithine antiporter catalyzes the uptake of putrescine via a proton symport mechanism%2C as well as the efflux of putrescine by a putrescine/ornithine antiport system gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03575 SG48_RS03580 SG48_0704 SG48_RS03580 717486 719684 - ornithine decarboxylase gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03580 SG48_RS03585 SG48_0705 SG48_RS03585 719807 720064 + hypothetical protein gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03585 SG48_RS03590 SG48_0706 SG48_RS03590 720280 720957 - two-component system response regulator response regulator in two-component regulatory system with KdpD%3B regulates the kdp operon involved in potassium transport gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03590 SG48_RS03595 SG48_0707 SG48_RS03595 720954 723638 - two-component system sensor histidine kinase KdpD sensory histidine kinase in two-component regulatory system with KdpE%3B signal sensing protein gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03595 SG48_RS03600 SG48_0708 SG48_RS03600 723631 724203 - potassium-transporting ATPase C chain One of the components of the high-affinity ATP-driven potassium transport (or KDP)system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03600 SG48_RS03605 SG48_0709 SG48_RS03605 724212 726260 - potassium-transporting ATPase B chain One of the components of the high-affinity ATP-driven potassium transport (or KDP) system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03605 SG48_RS03610 SG48_0710 SG48_RS03610 726283 727956 - potassium-transporting ATPase A chain catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03610 SG48_RS03615 SG48_0711 kdpF kdpF 727956 728045 - protein KdpF one of the components of the high-affinity ATP-driven potassium transport (or KDP) system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03615 SG48_RS03620 SG48_0712 SG48_RS03620 728358 728564 + DUF2517 domain-containing protein gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03620 SG48_RS03625 SG48_0713 SG48_RS03625 728807 733000 + RHS element protein gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03625 SG48_RS03630 SG48_0714 SG48_RS03630 733000 733326 + membrane protein gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03630 SG48_RS03635 SG48_RS03635 SG48_RS03635 733444 734877 + hypothetical protein gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03635 SG48_RS03640 SG48_0716 SG48_RS03640 734874 735443 + hypothetical protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03640 SG48_RS03645 SG48_RS03645 SG48_RS03645 735669 735923 + transposase gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03645 SG48_RS03650 SG48_RS03650 SG48_RS03650 736142 737185 + hypothetical protein gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03650 SG48_RS03655 SG48_0719 SG48_RS03655 737316 738077 + hypothetical protein gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03655 SG48_RS03660 SG48_0720 SG48_RS03660 738225 738734 + DUF1722 domain-containing protein gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03660 SG48_RS03665 SG48_0721 SG48_RS03665 738731 740149 + deoxyribodipyrimidine photolyase UV-induced DNA repair%3B converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers%3B light dependent gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03665 SG48_RS03670 SG48_0722 SG48_RS03670 740299 741780 - dipeptide permease D gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03670 SG48_RS03675 SG48_0723 SG48_RS03675 742051 742794 + Nif3-like dinuclear metal center hexameric protein gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03675 SG48_RS03680 SG48_0724 SG48_RS03680 742817 743473 + hypothetical protein gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03680 SG48_RS03685 SG48_0725 SG48_RS03685 743467 744399 + allophanate hydrolase gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03685 SG48_RS03690 SG48_0726 SG48_RS03690 744389 745123 + hypothetical protein gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03690 SG48_RS03695 SG48_0727 SG48_RS03695 745159 745950 + endonuclease VII 5-formyluracil/5-hydroxymethyluracil DNA glycosylase%3B involved in base excision repair of DNA damaged by oxidation or by mutagenic agents%3B acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines%3B has apurinic/apyrimidinic lyase activity gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03695 SG48_RS03700 SG48_0728 SG48_RS03700 745947 746993 - protein AbrB gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03700 SG48_RS03705 SG48_0729 SG48_RS03705 747145 748206 - fimbrial protein gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03705 SG48_RS03710 SG48_0730 SG48_RS03710 748203 748931 - periplasmic pilin chaperone gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03710 SG48_RS03715 SG48_0731 SG48_RS03715 748946 751393 - outer membrane protein gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03715 SG48_RS03720 SG48_0732 SG48_RS03720 751453 752019 - fimbrial-like adhesin protein gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03720 SG48_RS03725 SG48_0733 gltA gltA 752409 753692 - citrate synthase type II enzyme%3B in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate%3B allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation%3B forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A%3B functions in TCA cycle%2C glyoxylate cycle and respiration%3B enzyme from Helicobacter pylori is not inhibited by NADH gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03725 SG48_RS03730 SG48_RS03730 SG48_RS03730 753680 753865 + citrate synthase gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03730 SG48_RS03735 SG48_0734 sdhC sdhC 754386 754790 + succinate dehydrogenase cytochrome b556 large membrane subunit gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03735 SG48_RS03740 SG48_0735 sdhD sdhD 754784 755131 + succinate dehydrogenase hydrophobic membrane anchor subunit gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03740 SG48_RS03745 SG48_0736 sdhA sdhA 755131 756897 + succinate dehydrogenase flavoprotein subunit part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03745 SG48_RS03750 SG48_0737 sdhB sdhB 756913 757629 + succinate dehydrogenase iron-sulfur subunit part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol%3B the catalytic subunits are similar to fumarate reductase gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03750 SG48_RS03755 SG48_RS03755 SG48_RS03755 757688 757948 + hypothetical protein gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03755 SG48_RS03760 SG48_0738 SG48_RS03760 757930 760731 + 2-oxoglutarate dehydrogenase E1 component gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03760 SG48_RS03765 SG48_0739 SG48_RS03765 760746 761963 + dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex component of 2-oxoglutarate dehydrogenase complex%3B catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03765 SG48_RS03770 SG48_0740 sucC sucC 762238 763404 + succinyl-CoA ligase subunit beta catalyzes the interconversion of succinyl-CoA and succinate gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03770 SG48_RS03775 SG48_0741 SG48_RS03775 763404 764273 + succinyl-CoA ligase subunit alpha Catalyzes the only substrate-level phosphorylation in the TCA cycle gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03775 SG48_RS03780 SG48_0742 SG48_RS03780 764377 765099 - mannosyl-D-glycerate transport/metabolism system repressor MngR regulates the succiny-lCoA synthetase operon gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03780 SG48_RS03785 SG48_0743 SG48_RS03785 765268 767184 + PTS 2-O-a-mannosyl-D-glycerate transporter subunit IIABC involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03785 SG48_RS03790 SG48_0744 SG48_RS03790 767202 769835 + mannosylglycerate hydrolase gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03790 SG48_RS03795 SG48_RS03795 SG48_RS03795 769860 770087 + hypothetical protein gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03795 SG48_RS03800 SG48_0745 SG48_RS03800 770682 772250 + cytochrome bd-I ubiquinol oxidase subunit 1 part of the aerobic respiratory chain%3B catalyzes the ubiquinol to ubiquinone gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03800 SG48_RS03805 SG48_0746 SG48_RS03805 772266 773405 + cytochrome bd-I ubiquinol oxidase subunit 2 gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03805 SG48_RS03810 SG48_0747 SG48_RS03810 773420 773533 + cytochrome bd-I ubiquinol oxidase subunit X gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03810 SG48_RS03815 SG48_0748 SG48_RS03815 773533 773826 + cyd operon protein YbgE gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03815 SG48_RS03820 SG48_0749 SG48_RS03820 773976 774380 + acyl-CoA thioester hydrolase YbgC catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters%3B physiological role remains unknown%3B involved in phospholipid metabolism%3B part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03820 SG48_RS03825 SG48_0750 SG48_RS03825 774386 775069 + colicin transporter membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03825 SG48_RS03830 SG48_0751 SG48_RS03830 775073 775501 + protein TolR membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03830 SG48_RS03835 SG48_0752 tolA tolA 775566 776831 + cell envelope integrity/translocation protein TolA inner membrane component of 7 member Tol-Pal envelope-spanning complex%3B involved in maintaining cell envelope integrity%3B utilized by colicins and filamentous phages for import%3B interacts with TolB%2C Pal%2C and through TolB to various outer membrane porins gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03835 SG48_RS03840 SG48_0753 tolB tolB 776964 778256 + protein TolB forms dimers%3B may be involved in cell envelope integrity%3B interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03840 SG48_RS03845 SG48_0754 SG48_RS03845 778291 778812 + peptidoglycan-associated lipoprotein gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03845 SG48_RS03850 SG48_0755 SG48_RS03850 778822 779613 + periplasmic TolA-binding protein periplasmic protein that interacts with TolA%3B the tol-pal system is probably involved in maintaining cell envelope integrity gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03850 SG48_RS03855 SG48_0756 SG48_RS03855 779778 779853 + tRNA-Lys tRNA gene770 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03855 SG48_RS03860 SG48_0757 SG48_RS03860 779989 780064 + tRNA-Val tRNA gene771 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03860 SG48_RS03865 SG48_0758 SG48_RS03865 780067 780142 + tRNA-Lys tRNA gene772 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03865 SG48_RS03870 SG48_0759 SG48_RS03870 780292 780367 + tRNA-Val tRNA gene773 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03870 SG48_RS03875 SG48_0760 SG48_RS03875 780371 780446 + tRNA-Lys tRNA gene774 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03875 SG48_RS03880 SG48_0761 SG48_RS03880 780593 780668 + tRNA-Lys tRNA gene775 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03880 SG48_RS03885 SG48_0762 SG48_RS03885 780801 780876 + tRNA-Lys tRNA gene776 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03885 SG48_RS03890 SG48_0763 SG48_RS03890 781309 782352 + quinolinate synthase A 3 different subfamilies%3B catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03890 SG48_RS03895 SG48_0764 SG48_RS03895 782390 783109 + nicotinamide riboside transporter PnuC involved in nicotinamide riboside transport gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03895 SG48_RS03900 SG48_0765 SG48_RS03900 783106 784047 - zinc transporter ZitB involved in zinc efflux across the cytoplasmic membrane gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03900 SG48_RS03905 SG48_0766 SG48_RS03905 784161 784541 - periplasmic protein gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03905 SG48_RS03910 SG48_RS03910 SG48_RS03910 784636 784749 - glutamate decarboxylase gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03910 SG48_RS03915 SG48_0767 SG48_RS03915 784857 785909 + phospho-2-dehydro-3-deoxyheptonate aldolase Phe-sensitive catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C phenylalanine sensitive gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03915 SG48_RS03920 SG48_0768 gpmA gpmA 786067 786819 - 2%2C3-bisphosphoglycerate-dependent phosphoglycerate mutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03920 SG48_RS03925 SG48_0769 galM galM 787021 788061 - aldose 1-epimerase mutarotase%3B catalyzes the conversion of beta-galactose to the alpha-anomer%3B links the metabolism of lactose and galactose gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03925 SG48_RS03930 SG48_0770 SG48_RS03930 788055 789203 - galactokinase catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03930 SG48_RS03935 SG48_0771 SG48_RS03935 789207 790253 - galactose-1-phosphate uridylyltransferase catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03935 SG48_RS03940 SG48_0772 SG48_RS03940 790263 791279 - UDP-glucose 4-epimerase gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03940 SG48_RS03945 SG48_0773 SG48_RS03945 791540 793012 - molybdate ABC transporter ATPase contains 2 ATP-binding cassettes%3B involved in the transport of molybdenum gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03945 SG48_RS03950 SG48_0774 SG48_RS03950 793080 793868 - transcriptional regulator ModE represses the modABCD operon and activates the moaABCD and napFDAGHBC operons gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03950 SG48_RS03955 SG48_0775 SG48_RS03955 793997 794146 + multidrug efflux pump accessory protein AcrZ gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03955 SG48_RS03960 SG48_0776 modA modA 794313 795086 + molybdate-binding periplasmic protein with ModCB is involved in the high-affinity transport of molybdate gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03960 SG48_RS03965 SG48_0777 modB modB 795086 795775 + molybdenum ABC transporter permease part of ModCBA molybdate transporter%3B member of ABC superfamily%3B inner membrane component%3B regulated by repressor protein ModE gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03965 SG48_RS03970 SG48_0778 modC modC 795778 796836 + molybdenum import ATP-binding protein ModC Part of the ABC transporter complex modABC involved in molybdenum import gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03970 SG48_RS03975 SG48_0779 SG48_RS03975 796837 797655 - pyridoxal phosphate phosphatase YbhA gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03975 SG48_RS03980 SG48_0780 SG48_RS03980 797810 798805 + 6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03980 SG48_RS03985 SG48_0781 SG48_RS03985 798846 799799 - transcriptional regulator gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03985 SG48_RS03990 SG48_0782 SG48_RS03990 799983 801035 + PrpF family isomerase gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03990 SG48_RS03995 SG48_0783 SG48_RS03995 801111 802544 + hypothetical protein gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS03995 SG48_RS04000 SG48_0784 SG48_RS04000 802727 804988 + hydratase gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04000 SG48_RS04005 SG48_0785 SG48_RS04005 805222 806505 - acyl-CoA thioesterase gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04005 SG48_RS04010 SG48_0786 SG48_RS04010 806657 807133 - kinase inhibitor homolog%2C UPF0098 family YbhB%3B similar to rat and human kinase inhibitory proteins gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04010 SG48_RS04015 SG48_0787 SG48_RS04015 807192 808424 - adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7%2C8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04015 SG48_RS04020 SG48_0788 SG48_RS04020 808568 809608 + biotin synthase catalyzes the formation of biotin from dethiobiotin gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04020 SG48_RS04025 SG48_0789 SG48_RS04025 809605 810759 + 8-amino-7-oxononanoate synthase catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04025 SG48_RS04030 SG48_0790 SG48_RS04030 810746 811501 + malonyl-[acyl-carrier protein] O-methyltransferase BioC methyltransferase%3B acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA%2C a biotin precursor%3B member of the bio operon (bioABFCD)%3B in Escherichia coli%2C bioC-null mutants require biotin for growth gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04030 SG48_RS04035 SG48_0791 bioD bioD 811494 812171 + ATP-dependent dethiobiotin synthetase BioD 1 DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04035 SG48_RS04040 SG48_0792 SG48_RS04040 812750 814771 + UvrABC system protein B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands%2C where it probes for the presence of a lesion gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04040 SG48_RS04045 SG48_0793 SG48_RS04045 814963 815871 - hypothetical protein gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04045 SG48_RS04050 SG48_RS04050 SG48_RS04050 816114 816269 - hypothetical protein gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04050 SG48_RS04055 SG48_0794 moaA moaA 816268 817257 + cyclic pyranopterin monophosphate synthase together with moaC%2C is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04055 SG48_RS04060 SG48_0795 SG48_RS04060 817279 817791 + molybdenum cofactor biosynthesis protein B gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04060 SG48_RS04065 SG48_0796 moaC moaC 817794 818279 + cyclic pyranopterin monophosphate synthase accessory protein MoaC%3B along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z%3B involved in molybdenum cofactor biosynthesis gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04065 SG48_RS04070 SG48_0797 moaD moaD 818272 818517 + molybdopterin synthase sulfur carrier subunit catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04070 SG48_RS04075 SG48_0798 moaE moaE 818519 818971 + molybdopterin synthase catalytic subunit catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04075 SG48_RS04080 SG48_0799 SG48_RS04080 819108 819812 + hypothetical protein gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04080 SG48_RS04085 SG48_0800 SG48_RS04085 820017 820730 + Bax protein gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04085 SG48_RS04090 SG48_0801 SG48_RS04090 820766 821722 - hypothetical protein gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04090 SG48_RS04095 SG48_0802 SG48_RS04095 821722 822963 - cardiolipin synthase B gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04095 SG48_RS04100 SG48_0803 SG48_RS04100 822960 823721 - hypothetical protein gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04100 SG48_RS04105 SG48_0804 SG48_RS04105 823854 824264 + hypothetical protein gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04105 SG48_RS04110 SG48_0805 SG48_RS04110 824226 825332 - inner membrane transport permease YbhR gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04110 SG48_RS04115 SG48_0806 SG48_RS04115 825343 826476 - inner membrane transport permease YbhS gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04115 SG48_RS04120 SG48_0807 SG48_RS04120 826469 828205 - ABC transporter ATPase gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04120 SG48_RS04125 SG48_0808 SG48_RS04125 828198 829193 - transporter gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04125 SG48_RS04130 SG48_0809 SG48_RS04130 829196 829867 - DUF1956 domain-containing tetR family transcriptional regulator gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04130 SG48_RS04135 SG48_0810 SG48_RS04135 830096 831460 + ATP-dependent RNA helicase RhlE this helicase is not essential cell growth gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04135 SG48_RS04140 SG48_0811 SG48_RS04140 831692 832141 - swarming motility protein gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04140 SG48_RS04145 SG48_0812 dinG dinG 832294 834444 + ATP-dependent helicase DinG helicase involved in DNA repair and perhaps also replication gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04145 SG48_RS04150 SG48_0813 SG48_RS04150 834472 835434 + family 3 glycosyltransferase gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04150 SG48_RS04155 SG48_0814 SG48_RS04155 835575 836660 + dehydrogenase gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04155 SG48_RS04160 SG48_0815 SG48_RS04160 836889 837149 - hypothetical protein gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04160 SG48_RS04165 SG48_0816 SG48_RS04165 837414 837680 - RNA polymerase-binding protein DksA gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04165 SG48_RS04170 SG48_0817 SG48_RS04170 837754 838431 - PKHD-type hydroxylase gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04170 SG48_RS04175 SG48_0818 SG48_RS04175 838473 840755 - catecholate siderophore receptor Fiu Fiu%3B YbiL%3B porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine%2C dihydroxybenzoate) and beta lactam agents%3B Fiu interacts with TonB which provides the energy required for transport across the outer membrane%3B acts as a receptor for iron-siderophores and microcins E492%2C M%2C and H47%3B outer membrane protein gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04175 SG48_RS04180 SG48_0819 SG48_RS04180 841020 841280 - colanic acid mucoidy stimulation protein gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04180 SG48_RS04185 SG48_0820 SG48_RS04185 841556 842482 + ribosomal RNA large subunit methyltransferase F gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04185 SG48_RS04190 SG48_0821 SG48_RS04190 842479 844704 - moderate conductance mechanosensitive channel YbiO gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04190 SG48_RS04195 SG48_0822 glnQ glnQ 844965 845687 - glutamine transport ATP-binding protein GlnQ similar to ATP-binding component of ABC transporters gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04195 SG48_RS04200 SG48_0823 glnP glnP 845684 846343 - glutamine ABC transporter permease similar to permease component of ABC transporters%3B mutations impair ability of Escherichia coli to transport and utilize glutamine gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04200 SG48_RS04205 SG48_0824 glnH glnH 846482 847228 - glutamine-binding periplasmic protein similar to periplasmic-binding component of ABC transporters gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04205 SG48_RS04210 SG48_RS04210 SG48_RS04210 847274 847567 - hypothetical protein gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04210 SG48_RS04215 SG48_0825 SG48_RS04215 847632 848135 - DNA protection during starvation protein binds DNA in a non-sequence-specific manner and is abundant during stationary phase%3B forms a DNA-protein crystal that protects DNA from damage%3B required for normal starvation response and long-term stationary viability%3B forms a homododecameric complex and sequesters iron which provides protection against oxidative damage gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04215 SG48_RS04220 SG48_0826 SG48_RS04220 848434 849321 - threonine/homoserine exporter RhtA gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04220 SG48_RS04225 SG48_0827 ompX ompX 849674 850189 + outer membrane protein X OmpX%3B involved in cell adhesion%3B forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface%3B mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04225 SG48_RS04230 SG48_0828 SG48_RS04230 850238 851821 - phosphoethanolamine transferase OpgE gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04230 SG48_RS04235 SG48_RS04235 SG48_RS04235 852093 852221 - small protein MntS gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04235 SG48_RS04240 SG48_0829 SG48_RS04240 852407 852874 + transcriptional regulator MntR Transcriptional regulator that represses the manganese transporter MntH when manganese is present gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04240 SG48_RS04245 SG48_0830 SG48_RS04245 852871 853989 + hypothetical protein gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04245 SG48_RS04250 SG48_0831 SG48_RS04250 854048 854968 - transpeptidase gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04250 SG48_RS04255 SG48_0832 SG48_RS04255 855187 856779 + ABC transporter ATP-binding protein gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04255 SG48_RS04260 SG48_0833 SG48_RS04260 857020 858285 - DUF1479 domain-containing protein gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04260 SG48_RS04265 SG48_0834 SG48_RS04265 858437 859252 - sugar phosphatase YbiV gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04265 SG48_RS04270 SG48_0835 SG48_RS04270 859398 861830 - pyruvate formate lyase gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04270 SG48_RS04275 SG48_0836 SG48_RS04275 861836 862735 - pyruvate formate lyase activating enzyme gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04275 SG48_RS04280 SG48_0837 SG48_RS04280 862866 863528 + fructose-6-phosphate aldolase 1 similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04280 SG48_RS04285 SG48_0838 SG48_RS04285 863604 864353 - molybdopterin-synthase adenylyltransferase gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04285 SG48_RS04290 SG48_0839 SG48_RS04290 864353 865588 - molybdopterin molybdenumtransferase is involved in the formation of active molybdenum cofactor and the chelation of molybdenum gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04290 SG48_RS04295 SG48_0840 SG48_RS04295 865792 866757 + isoaspartyl peptidase gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04295 SG48_RS04300 SG48_0841 SG48_RS04300 866744 868615 + glutathione import ATP-binding protein GsiA with GsiBCD is involved in glutathione import%3B GsiA contains 2 ATP-binding domains gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04300 SG48_RS04305 SG48_0842 SG48_RS04305 868635 870173 + glutathione-binding protein GsiB with GsiACD is involved in the transport of glutathione into the cell gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04305 SG48_RS04310 SG48_0843 SG48_RS04310 870191 871111 + glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04310 SG48_RS04315 SG48_0844 SG48_RS04315 871114 872025 + glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04315 SG48_RS04320 SG48_0845 SG48_RS04320 872203 874551 + cyclic-di-GMP phosphodiesterase gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04320 SG48_RS04325 SG48_0846 SG48_RS04325 874559 875887 + diguanylate cyclase gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04325 SG48_RS04330 SG48_0847 rimO rimO 875934 877259 - ribosomal protein S12 methylthiotransferase RimO catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04330 SG48_RS04335 SG48_0848 bssR bssR 877472 877855 + biofilm regulator BssR BssS%3B regulator of biofilm through signal secretion%3B disruption of this gene in Escherichia coli led to effects on biofilm formation%2C alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04335 SG48_RS04340 SG48_0849 SG48_RS04340 877966 879081 + soluble aldose sugar dehydrogenase YliI gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04340 SG48_RS04345 SG48_0850 SG48_RS04345 879078 879704 - glutathione S-transferase gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04345 SG48_RS04350 SG48_0851 SG48_RS04350 879951 881153 + D-alanyl-D-alanine carboxypeptidase gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04350 SG48_RS04355 SG48_0852 SG48_RS04355 881200 881958 - DeoR family transcriptional regulator gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04355 SG48_RS04360 SG48_0853 SG48_RS04360 882016 882612 - undecaprenyl pyrophosphate phosphatase gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04360 SG48_RS04365 SG48_0854 SG48_RS04365 882897 884129 + multidrug transporter MdfA gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04365 SG48_RS04370 SG48_0855 SG48_RS04370 884170 884448 - hypothetical protein gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04370 SG48_RS04375 SG48_0856 SG48_RS04375 884540 885355 - flavin mononucleotide phosphatase YbjI gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04375 SG48_RS04380 SG48_0857 SG48_RS04380 885355 886563 - hypothetical protein gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04380 SG48_RS04385 SG48_0858 SG48_RS04385 886647 887183 + DNA-binding transcriptional regulator gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04385 SG48_RS04390 SG48_0860 SG48_RS04390 887358 889043 - transporter gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04390 SG48_RS04395 SG48_0861 SG48_RS04395 889313 889690 + hypothetical protein gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04395 SG48_RS04400 SG48_0862 SG48_RS04400 889720 889977 - glutaredoxin functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase%3B also involved in reducing some disulfides in a coupled system with glutathione reductase gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04400 SG48_RS04405 SG48_0863 SG48_RS04405 890137 890424 + DUF1418 domain-containing protein YbjC%3B located in the same operon as the nfsA gene%3B member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress%3B induced by paraquat%3B regulated by SoxS%3B unknown function gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04405 SG48_RS04410 SG48_0864 SG48_RS04410 890408 891130 + oxygen-insensitive NADPH nitroreductase NADPH-dependent%3B oxygen-insensitive%3B catalyzes the reduction of nitroaromatic compounds gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04410 SG48_RS04415 SG48_0865 SG48_RS04415 891191 892093 + ribosomal protein S6--L-glutamate ligase responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04415 SG48_RS04420 SG48_0866 SG48_RS04420 892181 892657 + negative regulator of motility%3B multicopy suppressor of coaA(Ts) gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04420 SG48_RS04425 SG48_RS04425 SG48_RS04425 892863 893024 + putrescine/spermidine ABC transporter substrate-binding protein gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04425 SG48_RS04430 SG48_0867 SG48_RS04430 893008 894120 + putrescine-binding periplasmic protein gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04430 SG48_RS04435 SG48_0868 potG potG 894215 895348 + putrescine transport ATP-binding protein PotG part of the PotFGHI ATP-dependent putrescine transporter gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04435 SG48_RS04440 SG48_0869 SG48_RS04440 895358 896311 + spermidine/putrescine ABC transporter permease gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04440 SG48_RS04445 SG48_0870 SG48_RS04445 896308 897153 + spermidine/putrescine ABC transporter permease gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04445 SG48_RS04450 SG48_0871 SG48_RS04450 897213 897701 + hypothetical protein gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04450 SG48_RS04455 SG48_0872 rumB rumB 897742 898869 + 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC RNA uridine methyltransferase B%3B catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04455 SG48_RS04460 SG48_0873 SG48_RS04460 899068 899799 - ABC transporter arginine-binding protein 1 with ArtPMQI is involved in arginine transport gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04460 SG48_RS04465 SG48_0874 artM artM 900090 900758 - arginine ABC transporter permease ArtM with ArtPQJI acts to transport arginine across the inner membrane gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04465 SG48_RS04470 SG48_0875 SG48_RS04470 900758 901474 - arginine ABC transporter permease ArtQ with ArtPMJI transports arginine across the inner membrane gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04470 SG48_RS04475 SG48_0876 SG48_RS04475 901481 902212 - arginine ABC transporter substrate-binding protein with ArtPMQI is involved in arginine transport gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04475 SG48_RS04480 SG48_0877 SG48_RS04480 902230 902958 - arginine transport ATP-binding protein ArtP gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04480 SG48_RS04485 SG48_0878 SG48_RS04485 903176 903691 - lipoprotein induced during stationary phase and by acivicin (a glutamine analog)%3B regulated by Lrp and RpoS gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04485 SG48_RS04490 SG48_0879 SG48_RS04490 903817 904140 + hypothetical protein gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04490 SG48_RS04495 SG48_0880 SG48_RS04495 904137 904967 + N-acetylmuramoyl-L-alanine amidase catalyzes the cleavage of the bond between muamic acid and l-alanine gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04495 SG48_RS04500 SG48_0881 SG48_RS04500 904964 905977 - NAD(P)H-dependent oxidoreductase gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04500 SG48_RS04505 SG48_0882 SG48_RS04505 906076 907506 - NAD-dependent oxidoreductase gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04505 SG48_RS04510 SG48_0883 SG48_RS04510 907517 908518 - low specificity L-threonine aldolase low- specificity%3B catalyzes the formation of acetaldehyde and glycine from L-threonine%3B acts on L-threonine%2C L-allo-threonine%2C L-threo-phenylserine%2C and L-erythro-phenylserine gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04510 SG48_RS04515 SG48_0884 SG48_RS04515 908555 910273 - pyruvate dehydrogenase [ubiquinone] catalyzes the formation of acetate from pyruvate gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04515 SG48_RS04520 SG48_0885 SG48_RS04520 910406 911374 - NADH oxidoreductase HCR gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04520 SG48_RS04525 SG48_0886 SG48_RS04525 911386 913038 - hydroxylamine reductase gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04525 SG48_RS04530 SG48_0887 SG48_RS04530 913182 914081 - transporter gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04530 SG48_RS04535 SG48_0888 SG48_RS04535 914576 915271 - aquaporin Z porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04535 SG48_RS04540 SG48_RS04540 SG48_RS04540 915484 915639 - hypothetical protein gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04540 SG48_RS04545 SG48_0889 SG48_RS04545 915697 917355 + OLD family ATP-dependent endonuclease%3B DUF2813 family protein gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04545 SG48_RS04550 SG48_0890 SG48_RS04550 917352 918344 - DUF535 domain-containing protein gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04550 SG48_RS04555 SG48_0891 SG48_RS04555 918459 919574 + MacA family efflux pump subunit confers macrolide resistance via active drug efflux gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04555 SG48_RS04560 SG48_0892 SG48_RS04560 919571 921517 + macrolide export ATP-binding/permease MacB with MacA is involved in the export of macrolide gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04560 SG48_RS04565 SG48_0893 SG48_RS04565 921590 921814 - cold-shock protein CspD inhibits DNA replication at both initiation and elongation steps%3B stationary phase and starvation inducible gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04565 SG48_RS04570 SG48_0894 clpS clpS 922137 922457 + ATP-dependent Clp protease adapter protein ClpS involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation%3B binds to the N-terminal domain of the chaperone ClpA gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04570 SG48_RS04575 SG48_0895 clpA clpA 922488 924764 + ATP-dependent Clp protease ATP-binding subunit ClpA ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease%3B directs protease to specific substrates gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04575 SG48_RS04580 SG48_0896 SG48_RS04580 925108 925195 - tRNA-Ser tRNA gene915 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04580 SG48_RS04585 SG48_0897 SG48_RS04585 925449 925667 - translation initiation factor IF-1 gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04585 SG48_RS04590 SG48_0898 aat aat 925952 926656 - leucyl/phenylalanyl-tRNA--protein transferase leucyltransferase%3B phenylalanyltransferse%3B functions in the N-end rule pathway%3B transfers Leu%2C Phe%2C Met%2C from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04590 SG48_RS04595 SG48_0899 SG48_RS04595 926698 928419 - ATP-binding/permease CydC in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04595 SG48_RS04600 SG48_0900 SG48_RS04600 928420 930186 - ATP-binding/permease CydD in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04600 SG48_RS04605 SG48_0901 SG48_RS04605 930309 931274 - thioredoxin reductase catalyzes the transfer of electrons from NADPH to thioredoxin%3B FAD/NAD(P) binding gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04605 SG48_RS04610 SG48_0902 SG48_RS04610 931819 932313 + leucine-responsive regulatory protein mediates a global response to leucine%3B acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04610 SG48_RS04615 SG48_0903 SG48_RS04615 932448 936437 + cell division protein FtsK DNA-binding membrane protein required for chromosome resolution and partitioning gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04615 SG48_RS04620 SG48_0904 lolA lolA 936596 937207 + outer membrane lipoprotein carrier protein LolA participates with LolB in the incorporation of lipoprotein into the outer membrane gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04620 SG48_RS04625 SG48_0905 SG48_RS04625 937218 938561 + replication-associated recombination protein A gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04625 SG48_RS04630 SG48_0906 SG48_RS04630 938652 939944 + serine--tRNA ligase gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04630 SG48_RS04635 SG48_0907 SG48_RS04635 940183 942627 + dimethyl sulfoxide reductase DmsA gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04635 SG48_RS04640 SG48_0908 SG48_RS04640 942638 943255 + dimethyl sulfoxide reductase subunit B oxidoreductase%2C Fe-S subunit%3B terminal electron transfer protein for the reduction of DMSO gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04640 SG48_RS04645 SG48_0909 SG48_RS04645 943257 944120 + dimethyl sulfoxide reductase subunit C gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04645 SG48_RS04650 SG48_0910 SG48_RS04650 944155 944781 - isochorismatase gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04650 SG48_RS04655 SG48_0911 SG48_RS04655 945095 946243 + MFS transporter inner membrane protein gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04655 SG48_RS04660 SG48_0912 SG48_RS04660 946453 947883 + inner membrane transporter YcaM gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04660 SG48_RS04665 SG48_0913 SG48_RS04665 947884 948792 - LysR family transcriptional regulator gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04665 SG48_RS04670 SG48_0914 SG48_RS04670 948892 949482 + NAD(P)H-dependent oxidoreductase gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04670 SG48_RS04675 SG48_0915 pflA pflA 949564 950304 - pyruvate formate-lyase 1-activating enzyme activates pyruvate formate-lyase 1 under anaerobic conditions gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04675 SG48_RS04680 SG48_0916 SG48_RS04680 950496 952778 - formate acetyltransferase 1 formate acetyltransferase%3B catalyzes the formation of formate and acetyl-CoA from pyruvate gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04680 SG48_RS04685 SG48_0917 SG48_RS04685 952833 953690 - formate transporter FocA gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04685 SG48_RS04690 SG48_0918 SG48_RS04690 954096 955856 - ribosomal protein S12 methylthiotransferase accessory factor YcaO gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04690 SG48_RS04695 SG48_0919 SG48_RS04695 955986 956678 + UPF0702 family inner membrane protein gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04695 SG48_RS04700 SG48_0920 SG48_RS04700 956877 957965 + phosphoserine aminotransferase catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate%3B catalyzes 4 phosphohydroxy L-threonine from 2-oxo 3 hydroxy 4- phosphobutanoate%3B required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04700 SG48_RS04705 SG48_0921 SG48_RS04705 958036 959319 + 3-phosphoshikimate 1-carboxyvinyltransferase gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04705 SG48_RS04710 SG48_0922 SG48_RS04710 959488 960252 + molecular chaperone gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04710 SG48_RS04715 SG48_0923 cmk cmk 960425 961108 + cytidylate kinase Catalyzes the formation of (d)CDP from ATP and (d)CMP gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04715 SG48_RS04720 SG48_0924 rpsA rpsA 961219 962892 + 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04720 SG48_RS04725 SG48_0925 ihfB ihfB 963052 963336 + integration host factor subunit beta This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04725 SG48_RS04730 SG48_0926 SG48_RS04730 963544 965808 + hypothetical protein gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04730 SG48_RS04735 SG48_0927 SG48_RS04735 965845 967593 + lipid A export ATP-binding/permease MsbA involved in the transport of lipid A across the inner membrane gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04735 SG48_RS04740 SG48_0928 lpxK lpxK 967590 968576 + tetraacyldisaccharide 4'-kinase transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1%2C4'-bis-phosphate gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04740 SG48_RS04745 SG48_0929 SG48_RS04745 968613 969845 + hypothetical protein gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04745 SG48_RS04750 SG48_0930 SG48_RS04750 969897 970079 + hypothetical protein gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04750 SG48_RS04755 SG48_0931 SG48_RS04755 970076 970822 + 3-deoxy-manno-octulosonate cytidylyltransferase CMP-2-keto-3-deoxyoctulosonic acid synthetase%3B catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04755 SG48_RS04760 SG48_0932 SG48_RS04760 970976 971869 + protein kinase-like domain protein gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04760 SG48_RS04765 SG48_0933 SG48_RS04765 971846 972625 - envelope biogenesis factor ElyC gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04765 SG48_RS04770 SG48_0934 SG48_RS04770 972761 973546 + protein SmtA gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04770 SG48_RS04775 SG48_0935 SG48_RS04775 973543 974865 + chromosome partition protein MukF acts with MukB and MukE to condense the chromosome and allow for segregation during cell division gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04775 SG48_RS04780 SG48_0936 SG48_RS04780 974846 975550 + chromosome partition protein MukE acts with MukB and MukF to condense the chromosome and allow for segregation during cell division gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04780 SG48_RS04785 SG48_0937 mukB mukB 975550 980010 + chromosome partition protein MukB SMC (structural maintenance of chromosomes) family of proteins%3B involved in chromosome condensatin and partitioning%3B forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ%3B mutations result in cell division defects gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04785 SG48_RS04790 SG48_0938 SG48_RS04790 980271 982118 + transpeptidase catalyzes the formation of a meso-diaminopimelyl- meso-diaminopimelyl crosslink gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04790 SG48_RS04795 SG48_0939 SG48_RS04795 982299 982847 + M15A protease-related family periplasmic protein gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04795 SG48_RS04800 SG48_0940 SG48_RS04800 982874 983521 + metal-binding enzyme gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04800 SG48_RS04805 SG48_0941 SG48_RS04805 983743 984933 - aspartate aminotransferase gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04805 SG48_RS04810 SG48_RS04810 SG48_RS04810 984932 985102 + hypothetical protein gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04810 SG48_RS04815 SG48_0942 SG48_RS04815 985118 986206 - outer membrane protein F gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04815 SG48_RS04820 SG48_0943 SG48_RS04820 986809 988209 - asparagine--tRNA ligase gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04820 SG48_RS04825 SG48_0944 SG48_RS04825 988378 989580 - nicotinate phosphoribosyltransferase catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04825 SG48_RS04830 SG48_0945 pepN pepN 989846 992458 + aminopeptidase N gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04830 SG48_RS04835 SG48_0946 ssuB ssuB 992501 993268 - aliphatic sulfonate ABC transporter ATP-binding protein part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic substrate-binding subunit%2C SsuB the ATP-binding subunit and SsuC the permease gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04835 SG48_RS04840 SG48_0947 ssuC ssuC 993265 994056 - aliphatic sulfonate ABC transporter permease part of the ABC type transport system for alkanesulfonate SsuABC%3B SsuB the ATP-binding subunit and SsuC the permease gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04840 SG48_RS04845 SG48_0948 SG48_RS04845 994067 995212 - alkanesulfonate monooxygenase catalyzes the release of sulfite from alkanesulfonates gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04845 SG48_RS04850 SG48_0949 SG48_RS04850 995209 996168 - aliphatic sulfonate ABC transporter substrate-binding protein part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04850 SG48_RS04855 SG48_0950 SG48_RS04855 996161 996736 - FMN reductase gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04855 SG48_RS04860 SG48_0951 SG48_RS04860 997092 997631 + fimbrial subunit ElfA gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04860 SG48_RS04865 SG48_0952 SG48_RS04865 997741 998415 + fimbrial protein gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04865 SG48_RS04870 SG48_0953 SG48_RS04870 998440 1001040 + usher protein ElfC involved in fimbria production gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04870 SG48_RS04875 SG48_0954 SG48_RS04875 1001031 1002101 + fimbrial-like adhesin protein gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04875 SG48_RS04880 SG48_0955 SG48_RS04880 1002203 1002655 + fimbrial protein gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04880 SG48_RS04885 SG48_0956 SG48_RS04885 1002663 1003178 + fimbrial-like adhesin protein gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04885 SG48_RS04890 SG48_0957 SG48_RS04890 1003171 1003881 + periplasmic pilin chaperone gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04890 SG48_RS04895 SG48_0958 SG48_RS04895 1003992 1005002 + dihydroorotate dehydrogenase catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B uses a flavin nucleotide as an essential cofactor%3B class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus%2C which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04895 SG48_RS04900 SG48_0959 SG48_RS04900 1005176 1005718 + cell division protein ZapC gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04900 SG48_RS04905 SG48_0960 SG48_RS04905 1005715 1006824 - 6-N-hydroxylaminopurine detoxification oxidoreductase gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04905 SG48_RS04910 SG48_0961 rlmL rlmL 1007068 1009176 + ribosomal RNA large subunit methyltransferase K/L catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04910 SG48_RS04915 SG48_0962 SG48_RS04915 1009188 1011095 + ABC transporter ATP-binding protein Uup%3B in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity%3B mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04915 SG48_RS04920 SG48_0963 SG48_RS04920 1011225 1012478 + paraquat-inducible protein A gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04920 SG48_RS04925 SG48_0964 SG48_RS04925 1012483 1014123 + paraquat-inducible protein B gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04925 SG48_RS04930 SG48_0965 SG48_RS04930 1014120 1014683 + DUF330 domain-containing protein gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04930 SG48_RS04935 SG48_0966 SG48_RS04935 1014939 1015106 + ribosome modulation factor gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04935 SG48_RS04940 SG48_0967 SG48_RS04940 1015176 1015694 - 3-hydroxydecanoyl-ACP dehydratase catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2%2C3-decenoyl-ACP or 3%2C4-decenoyl-ACP gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04940 SG48_RS04945 SG48_0968 SG48_RS04945 1015763 1017523 - peptidase gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04945 SG48_RS04950 SG48_0969 SG48_RS04950 1017709 1018161 + macrodomain Ter protein gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04950 SG48_RS04955 SG48_0970 SG48_RS04955 1018237 1019277 - outer membrane protein A OmpA is believed to be a porin%2C involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli%2C and it is known to play a role as a phage receptor%2C a mediator of F-factor dependent conjugation%2C and in maintaining the structural shape of the outer membrane%3B 3a%3B II*%3B G%3B d gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04955 SG48_RS04960 SG48_RS04960 SG48_RS04960 1019480 1019650 + hypothetical protein gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04960 SG48_RS04965 SG48_0971 SG48_RS04965 1019634 1020143 - cell division inhibitor SulA gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04965 SG48_RS04970 SG48_0972 SG48_RS04970 1020362 1020991 + protein Sxy gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04970 SG48_RS04975 SG48_0973 SG48_RS04975 1020954 1023107 - hypothetical protein gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04975 SG48_RS04980 SG48_0974 SG48_RS04980 1023126 1023572 - hypothetical protein gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04980 SG48_RS04985 SG48_0975 helD helD 1023695 1025749 + helicase IV catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04985 SG48_RS04990 SG48_0976 mgsA mgsA 1025781 1026239 - methylglyoxal synthase catalyzes the formation of methylglyoxal from glycerone phosphate gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04990 SG48_RS04995 SG48_0977 SG48_RS04995 1026335 1026997 - hypothetical protein gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS04995 SG48_RS05000 SG48_RS05000 SG48_RS05000 1027037 1027207 - hypothetical protein gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05000 SG48_RS05005 SG48_0978 SG48_RS05005 1027170 1027583 + CoA-binding protein gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05005 SG48_RS05010 SG48_0979 SG48_RS05010 1027628 1027945 - heat-shock protein HspQ gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05010 SG48_RS05015 SG48_0980 SG48_RS05015 1028003 1029193 - ribosomal RNA large subunit methyltransferase I SAM-dependent%3Bcatalyzes the methylation of cytosine at position 1962 of the 23S rRNA gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05015 SG48_RS05020 SG48_0981 SG48_RS05020 1029288 1029566 + acylphosphatase catalyzes the hydrolysis of acylphosphate gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05020 SG48_RS05025 SG48_0982 SG48_RS05025 1029563 1029892 - sulfurtransferase TusE transfers sulfur from TusBCD complex to MnmA%3B involved in thiouridation of U34 position of some tRNAs gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05025 SG48_RS05030 SG48_0983 SG48_RS05030 1029983 1030642 - Modulator of FtsH protease inner membrane protein binds to the HflBKC complex which modulates FtsH activity gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05030 SG48_RS05035 SG48_0984 SG48_RS05035 1030849 1030936 - tRNA-Ser tRNA gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05035 SG48_RS05040 SG48_0985 SG48_RS05040 1031363 1032481 + hydrogenase-1 small chain gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05040 SG48_RS05045 SG48_0986 SG48_RS05045 1032478 1034271 + hydrogenase-1 large chain gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05045 SG48_RS05050 SG48_0987 SG48_RS05050 1034290 1034997 + Ni/Fe-hydrogenase B-type cytochrome subunit gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05050 SG48_RS05055 SG48_0988 SG48_RS05055 1034994 1035581 + hydrogenase 1 maturation protease HyaD%3B endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05055 SG48_RS05060 SG48_0989 SG48_RS05060 1035578 1035976 + hydrogenase-1 operon protein HyaE involved in processing hydrogenase proteins HyaA and HyaB gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05060 SG48_RS05065 SG48_0990 SG48_RS05065 1035973 1036830 + hydrogenase-1 operon protein HyaF gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05065 SG48_RS05070 SG48_0991 SG48_RS05070 1036964 1038508 + cytochrome bd-II ubiquinol oxidase subunit 1 part of the aerobic respiratory chain%3B catalyzes the ubiquinol to ubiquinone gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05070 SG48_RS05075 SG48_0992 SG48_RS05075 1038520 1039656 + cytochrome bd-II ubiquinol oxidase subunit 2 gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05075 SG48_RS05080 SG48_0993 SG48_RS05080 1039669 1039761 + cytochrome bd-II oxidase subunit gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05080 SG48_RS05085 SG48_0994 SG48_RS05085 1039841 1041139 + periplasmic AppA protein gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05085 SG48_RS05090 SG48_0995 SG48_RS05090 1041254 1043434 - tyrosine-protein kinase etk gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05090 SG48_RS05095 SG48_0996 SG48_RS05095 1043454 1043900 - protein-tyrosine phosphatase Wzb shows phosphatase activity towards the autophosphorylated Wzc protein%2C which induces colanic acid biosynthesis%3B catalyzes the phosphorylation of UDP-glucose dehydrogenase%2C an enzyme involved in colanic acid biosynthesis gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05095 SG48_RS05100 SG48_0997 SG48_RS05100 1043888 1045027 - O-antigen capsule outer membrane auxillary protein export channel required for the translocation of capsular polysaccharide through the outer membrane gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05100 SG48_RS05105 SG48_0998 SG48_RS05105 1045073 1047169 - O-antigen capsule production periplasmic protein gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05105 SG48_RS05110 SG48_0999 SG48_RS05110 1047169 1047915 - O-antigen capsule production periplasmic protein gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05110 SG48_RS05115 SG48_1000 SG48_RS05115 1047912 1048556 - hypothetical protein gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05115 SG48_RS05120 SG48_1001 SG48_RS05120 1048663 1048968 - threonine-rich inner membrane protein GfcA gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05120 SG48_RS05125 SG48_RS05125 SG48_RS05125 1049090 1049305 - transposase gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05125 SG48_RS05130 SG48_1003 SG48_RS05130 1049251 1049754 + Insertion element IS1 4 protein InsB gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05130 SG48_RS05135 SG48_1004 SG48_RS05135 1050187 1050399 - cold-shock protein CspH gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05135 SG48_RS05140 SG48_1005 SG48_RS05140 1050685 1050897 + cold-shock protein CspG gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05140 SG48_RS05145 SG48_1006 SG48_RS05145 1051071 1051301 + cold-shock protein gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05145 SG48_RS05150 SG48_1007 SG48_RS05150 1051291 1051464 + protein GnsA gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05150 SG48_RS05155 SG48_1008 SG48_RS05155 1051513 1052586 - 4Fe-4S membrane protein gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05155 SG48_RS05160 SG48_1009 SG48_RS05160 1052658 1055372 - sensor histidine kinase Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05160 SG48_RS05165 SG48_1010 SG48_RS05165 1055485 1056513 + periplasmic protein TorT periplasmic sensory protein associated with the TorRS two-component regulatory system gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05165 SG48_RS05170 SG48_1011 SG48_RS05170 1056486 1057178 - two-component system response regulator gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05170 SG48_RS05175 SG48_1012 SG48_RS05175 1057308 1058480 + cytochrome c-type protein TorC with TorA forms the inducible trimethylamine N-oxide reductase which transfers electrons from menaquinones first to TorC then to TorA gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05175 SG48_RS05180 SG48_1013 SG48_RS05180 1058480 1061026 + trimethylamine-N-oxide reductase 1 catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05180 SG48_RS05185 SG48_1014 torD torD 1061023 1061622 + chaperone protein TorD TorD%3B involved in the biogenesis of torA%3B acts on torA before the insertion of the molybdenum cofactor and%2C as a result%2C probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05185 SG48_RS05190 SG48_1015 SG48_RS05190 1061774 1062079 - chaperone modulatory protein CbpM with CpbA modulates the activity of the dnaK chaperone system%3B interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05190 SG48_RS05195 SG48_1016 SG48_RS05195 1062079 1062999 - curved DNA-binding protein functional analog of DnaJ%3B co-chaperone with DnaK%2C molecular chaperone in an adaptive response to environmental stresses other than heat shock gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05195 SG48_RS05200 SG48_1017 SG48_RS05200 1063260 1064516 + hypothetical protein gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05200 SG48_RS05205 SG48_1018 SG48_RS05205 1064809 1066050 + glucose-1-phosphatase gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05205 SG48_RS05210 SG48_1019 SG48_RS05210 1066088 1066315 - hypothetical protein gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05210 SG48_RS05215 SG48_1020 SG48_RS05215 1066336 1066932 - NAD(P)H dehydrogenase (quinone) catalyzes the transfer of electrons from NADH to ubiquinone gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05215 SG48_RS05220 SG48_RS05220 SG48_RS05220 1067136 1067372 + hypothetical protein gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05220 SG48_RS05225 SG48_1021 SG48_RS05225 1067305 1067478 + KGG family protein gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05225 SG48_RS05230 SG48_1022 SG48_RS05230 1067735 1069063 - transporter gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05230 SG48_RS05235 SG48_1023 SG48_RS05235 1069084 1069578 - FMN reductase gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05235 SG48_RS05240 SG48_1024 SG48_RS05240 1069589 1070179 - malonic semialdehyde reductase RutE gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05240 SG48_RS05245 SG48_1025 SG48_RS05245 1070189 1070989 - reactive intermediate detoxifying aminoacrylate hydrolase gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05245 SG48_RS05250 SG48_1026 SG48_RS05250 1070997 1071383 - aminoacrylate deaminase reactive intermediate detoxification%3B weak enamine/imine deaminase activity gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05250 SG48_RS05255 SG48_1027 SG48_RS05255 1071395 1072087 - peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05255 SG48_RS05260 SG48_1028 SG48_RS05260 1072087 1073178 - pyrimidine monooxygenase RutA gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05260 SG48_RS05265 SG48_1029 SG48_RS05265 1073466 1074104 + transcriptional regulator gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05265 SG48_RS05270 SG48_1030 putA putA 1074144 1078106 - bifunctional protein PutA proline utilization protein A%3B multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate%3B in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus%3B forms dimers and is a peripherally membrane-associated protein gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05270 SG48_RS05275 SG48_RS05275 SG48_RS05275 1078161 1078370 + hypothetical protein gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05275 SG48_RS05280 SG48_1031 SG48_RS05280 1078529 1080037 + sodium/proline symporter involved in the sodium dependent uptake of proline gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05280 SG48_RS05285 SG48_RS05285 SG48_RS05285 1080223 1080544 - hypothetical protein gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05285 SG48_RS05290 SG48_RS05290 SG48_RS05290 1080580 1081409 + iron permease gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05290 SG48_RS05295 SG48_1033 SG48_RS05295 1081467 1082594 + iron uptake system component EfeO with EfeUB forms an iron transport system which is silent in E. coli K-12 due to a mutation in EfeU gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05295 SG48_RS05300 SG48_1034 SG48_RS05300 1082600 1083871 + deferrochelatase/peroxidase EfeB gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05300 SG48_RS05305 SG48_RS05305 SG48_RS05305 1083789 1084136 - hypothetical protein gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05305 SG48_RS05310 SG48_RS05310 SG48_RS05310 1084492 1085280 + hypothetical protein gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05310 SG48_RS05315 SG48_1036 pgaD pgaD 1085330 1085743 - poly-beta-1%2C6-N-acetyl-D-glucosamine biosynthesis protein PgaD in Yersinia this gene is involved in biofilm formation and hemin adsorption%3B in Escherichia coli it is involved in PGA biosynthesis and export gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05315 SG48_RS05320 SG48_1037 SG48_RS05320 1085745 1086983 - N-glycosyltransferase predicted polysaccharide polymerase involved in biofilm formation%3B required for the synthesis of the beta-1%2C6-N-acetylglucosamine polysaccharide%3B PgaC%3B in Yersinia the HmsR protein is an inner membrane protein gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05320 SG48_RS05325 SG48_1038 pgaB pgaB 1087063 1089081 - poly-beta-1%2C6-N-acetyl-D-glucosamine N-deacetylase in Yersinia this protein is involved in biofilm formation and hemin adsorption%3B related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1%2C6-N-acetyl-D-glucosamine (PGA) export gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05325 SG48_RS05330 SG48_1039 pgaA pgaA 1089090 1091513 - poly-beta-1%2C6-N-acetyl-D-glucosamine export protein outer membrane protein essential for the synthesis of poly-beta-1%2C6-N-acetyl-D-glucosamine (PGA)%3B adhesin required for biofilm formation%3B PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface%3B member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05330 SG48_RS05335 SG48_1040 SG48_RS05335 1092100 1093458 + diguanylate cyclase gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05335 SG48_RS05340 SG48_1041 SG48_RS05340 1093499 1094365 - transposase gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05340 SG48_RS05345 SG48_1042 SG48_RS05345 1094362 1094661 - transposase gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05345 SG48_RS05350 SG48_RS05350 SG48_RS05350 1094747 1095070 + hypothetical protein gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05350 SG48_RS05355 SG48_1044 SG48_RS05355 1095067 1096053 + hypothetical protein gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05355 SG48_RS05360 SG48_RS05360 SG48_RS05360 1096325 1096423 + hypothetical protein gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05360 SG48_RS05365 SG48_1045 SG48_RS05365 1096789 1096876 - tRNA-Ser tRNA gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05365 SG48_RS05370 SG48_1046 ghrA ghrA 1097110 1098048 + glyoxylate/hydroxypyruvate reductase A catalyzes the formation of glycolate and glycerate from glyoxylate and hydroxypyruvate%2C respectively gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05370 SG48_RS05375 SG48_1047 SG48_RS05375 1098103 1098840 + phosphatase gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05375 SG48_RS05380 SG48_1048 SG48_RS05380 1098864 1099418 + chaperone protein YcdY gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05380 SG48_RS05385 SG48_1049 SG48_RS05385 1099520 1100011 + hypothetical protein gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05385 SG48_RS05390 SG48_1050 SG48_RS05390 1100075 1100908 - curli production assembly/transport component CsgG involved in the stability of the curlin proteins during assembly%3B involved in the secretion of the major curlin subunit CsgA across the outer membrane gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05390 SG48_RS05395 SG48_1051 SG48_RS05395 1100935 1101351 - curli production assembly/transport component CsgF nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation)%3B part of the curli secretion and assembly protein complex gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05395 SG48_RS05400 SG48_1052 SG48_RS05400 1101376 1101765 - curli production assembly/transport component CsgE chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation)%3B part of the curli secretion and assembly protein complex gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05400 SG48_RS05405 SG48_1053 SG48_RS05405 1101770 1102420 - CsgBAC operon transcriptional regulatory protein activates the csgBA and csgDEFG operons involved in biofilm formation gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05405 SG48_RS05410 SG48_RS05410 SG48_RS05410 1102887 1103072 - hypothetical protein gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05410 SG48_RS05415 SG48_1054 csgB csgB 1103175 1103630 + minor curlin subunit CsgB%3B functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05415 SG48_RS05420 SG48_1055 csgA csgA 1103671 1104126 + major curlin subunit the major structural subunit of curlin which assemble to form curli which can bind to fibronectin gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05420 SG48_RS05425 SG48_1056 csgC csgC 1104185 1104517 + curli assembly protein CsgC involved in autoagglutination of curliated cells%3B not involved in production of curli fibers gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05425 SG48_RS05430 SG48_1057 SG48_RS05430 1104638 1104949 + hypothetical protein gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05430 SG48_RS05435 SG48_1058 SG48_RS05435 1105044 1105577 + O-acetyl-ADP-ribose deacetylase interacts and inactivates RNase III during cold shock gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05435 SG48_RS05440 SG48_1059 SG48_RS05440 1105579 1107000 + cardiolipin synthase C gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05440 SG48_RS05445 SG48_1060 opgC opgC 1107008 1108165 - glucan biosynthesis protein C required for the transfer of succinyl residues to osmoregulated periplasmic glucans gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05445 SG48_RS05450 SG48_RS05450 SG48_RS05450 1108210 1108353 - hypothetical protein gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05450 SG48_RS05455 SG48_RS05455 SG48_RS05455 1108357 1108488 - hypothetical protein gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05455 SG48_RS05460 SG48_1061 mdoG mdoG 1108541 1110094 + glucan biosynthesis protein G involved in the biosynthesis of osmoregulated periplasmic glucans%3B required for the assembly of the polyglucose structure of glucan gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05460 SG48_RS05465 SG48_1062 SG48_RS05465 1110117 1112630 + glucosyltransferase necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05465 SG48_RS05470 SG48_1063 SG48_RS05470 1112803 1113030 + outer membrane integrity lipoprotein gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05470 SG48_RS05475 SG48_1064 SG48_RS05475 1113031 1113405 - acidic protein MsyB gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05475 SG48_RS05480 SG48_RS05480 SG48_RS05480 1113435 1113533 - hypothetical protein gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05480 SG48_RS05485 SG48_1065 SG48_RS05485 1113488 1114714 - multidrug resistance protein MdtG Confers resistance to fosfomycin and deoxycholate gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05485 SG48_RS05490 SG48_1066 SG48_RS05490 1114886 1115806 - lipid A biosynthesis lauroyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05490 SG48_RS05495 SG48_1067 SG48_RS05495 1116031 1117083 + rhodanese-related sulfurtransferase gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05495 SG48_RS05500 SG48_1068 SG48_RS05500 1117125 1117700 - hypothetical protein gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05500 SG48_RS05505 SG48_1069 SG48_RS05505 1117704 1118270 - cytochrome b561 homolog 2 gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05505 SG48_RS05510 SG48_1070 SG48_RS05510 1118531 1118644 - hypothetical protein gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05510 SG48_RS05515 SG48_1071 solA solA 1118692 1119810 - N-methyl-L-tryptophan oxidase catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde%3B FAD-binding%3B can also catalyze the demethylation of other N-methyl amino acids gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05515 SG48_RS05520 SG48_1072 bssS bssS 1119925 1120179 - biofilm regulator BssS BssS%3B regulator of biofilm through signal secretion%3B disruption of this gene in Escherichia coli led to effects on biofilm formation%2C alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05520 SG48_RS05525 SG48_1073 SG48_RS05525 1120466 1120711 - DNA-damage-inducible protein I gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05525 SG48_RS05530 SG48_1074 SG48_RS05530 1120785 1121831 - dihydroorotase gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05530 SG48_RS05535 SG48_1075 SG48_RS05535 1121937 1122497 - lipoprotein gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05535 SG48_RS05540 SG48_1076 SG48_RS05540 1122631 1123278 - glutaredoxin cofactor involved in the reduction of disulfides gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05540 SG48_RS05545 SG48_1077 SG48_RS05545 1123342 1124550 - multidrug resistance protein MdtH Confers resistance to norfloxacin and enoxacin gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05545 SG48_RS05550 SG48_1078 SG48_RS05550 1124786 1125370 + ribosomal-protein-alanine acetyltransferase gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05550 SG48_RS05555 SG48_1079 SG48_RS05555 1125381 1126028 + hypothetical protein gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05555 SG48_RS05560 SG48_1080 SG48_RS05560 1126030 1126953 + oxidoreductase gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05560 SG48_RS05565 SG48_1081 SG48_RS05565 1127063 1128598 + lipid II flippase MurJ gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05565 SG48_RS05570 SG48_1082 SG48_RS05570 1128638 1129054 - flagella synthesis protein FlgN export chaperone for FlgK and FlgL gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05570 SG48_RS05575 SG48_1083 SG48_RS05575 1129059 1129352 - negative regulator of flagellin synthesis regulates the flagellar specific sigma28 transcription factor gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05575 SG48_RS05580 SG48_1084 flgA flgA 1129428 1130087 - flagella basal body P-ring formation protein FlgA required for the assembly of the flagellar basal body P-ring gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05580 SG48_RS05585 SG48_1085 flgB flgB 1130242 1130658 + flagellar biosynthesis protein FlgB with FlgF and C makes up the proximal portion of the flagellar basal body rod%3B Vibrio parahaemolyticus protein is associated with the polar flagella gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05585 SG48_RS05590 SG48_1086 flgC flgC 1130662 1131066 + flagellar basal-body rod protein FlgC with FlgF and B makes up the proximal portion of the flagellar basal body rod gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05590 SG48_RS05595 SG48_1087 flgD flgD 1131078 1131773 + flagellar basal body rod modification protein FlgD acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of some flagellar genes%3B in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05595 SG48_RS05600 SG48_1088 flgE flgE 1131798 1133006 + flagellar hook protein FlgE the hook connects flagellar basal body to the flagellar filament gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05600 SG48_RS05605 SG48_1089 flgF flgF 1133026 1133781 + flagellar basal-body rod protein FlgF FlgF%2C with FlgB and C%2C makes up the proximal portion of the flagellar basal body rod gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05605 SG48_RS05610 SG48_1090 flgG flgG 1133953 1134735 + flagellar basal body rod protein FlgG makes up the distal portion of the flagellar basal body rod gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05610 SG48_RS05615 SG48_1091 flgH flgH 1134788 1135486 + flagellar L-ring protein part of the flagellar basal body which consists of four rings L%2CP%2C S and M mounted on a central rod gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05615 SG48_RS05620 SG48_1092 flgI flgI 1135498 1136595 + flagellar P-ring protein part of the basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod%3B Vibrio parahaemolyticus%2C Yersinia%2C Bradyrhizobium and other bacteria have two copies of this and other flagellar genes%3B the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05620 SG48_RS05625 SG48_1093 flgJ flgJ 1136595 1137536 + peptidoglycan hydrolase FlgJ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05625 SG48_RS05630 SG48_1094 flgK flgK 1137602 1139245 + flagellar hook-associated protein 1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05630 SG48_RS05635 SG48_1095 flgL flgL 1139257 1140210 + flagellar hook-associated protein with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05635 SG48_RS05640 SG48_1096 rne rne 1140406 1143591 - ribonuclease E bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein%3B forms part of the membrane-associated degradosome complex along with PNPase%2C RhlB%2C and enolase gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05640 SG48_RS05645 SG48_1097 SG48_RS05645 1143726 1144046 + hypothetical protein gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05645 SG48_RS05650 SG48_1098 SG48_RS05650 1144164 1145123 + ribosomal large subunit pseudouridine synthase C catalyzes the transformation of uracil to pseudouracil at nucleotides U955%2C U2504%2C and U2580 in 23S rRNA gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05650 SG48_RS05655 SG48_1099 SG48_RS05655 1145235 1145819 - m(7)GTP pyrophosphatase Maf%3B overexpression in Bacillus subtilis inhibits septation in the dividing cell gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05655 SG48_RS05660 SG48_1101 SG48_RS05660 1146018 1146539 + DUF177 domain-containing protein gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05660 SG48_RS05665 SG48_1102 rpmF rpmF 1146591 1146764 + 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05665 SG48_RS05670 SG48_1103 SG48_RS05670 1146875 1147915 + phosphate acyltransferase gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05670 SG48_RS05675 SG48_1104 SG48_RS05675 1147983 1148936 + 3-oxoacyl-ACP synthase III FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05675 SG48_RS05680 SG48_1105 SG48_RS05680 1148952 1149881 + malonyl CoA-ACP transacylase gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05680 SG48_RS05685 SG48_1106 fabG fabG 1149894 1150628 + 3-oxoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05685 SG48_RS05690 SG48_1107 SG48_RS05690 1150839 1151075 + acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05690 SG48_RS05695 SG48_1108 SG48_RS05695 1151163 1152404 + 3-oxoacyl-ACP synthase II FabF%3B beta-ketoacyl-ACP synthase II%2C KASII%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05695 SG48_RS05700 SG48_1109 SG48_RS05700 1152524 1153333 + aminodeoxychorismate lyase catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05700 SG48_RS05705 SG48_1110 SG48_RS05705 1153336 1154358 + septation protein%2C ampicillin sensitivity gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05705 SG48_RS05710 SG48_1111 SG48_RS05710 1154348 1154989 + thymidylate kinase gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05710 SG48_RS05715 SG48_1112 SG48_RS05715 1154986 1155990 + DNA polymerase III subunit delta' catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05715 SG48_RS05720 SG48_1113 SG48_RS05720 1156001 1156798 + DNAse gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05720 SG48_RS05725 SG48_1114 SG48_RS05725 1157093 1158526 + PTS glucose EIICB component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05725 SG48_RS05730 SG48_1115 SG48_RS05730 1158586 1160775 - fhuE receptor gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05730 SG48_RS05735 SG48_1116 SG48_RS05735 1161109 1161468 + HIT-like protein HinT gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05735 SG48_RS05740 SG48_1117 SG48_RS05740 1161471 1161848 + hypothetical protein gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05740 SG48_RS05745 SG48_1118 SG48_RS05745 1161862 1162503 + penicillin-binding protein activator LpoB gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05745 SG48_RS05750 SG48_1119 thiK thiK 1162484 1163308 + thiamine kinase catalyzes the phosphorylation of thiamine to thiamine phosphate gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05750 SG48_RS05755 SG48_1120 SG48_RS05755 1163319 1164344 + beta-hexosaminidase hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05755 SG48_RS05760 SG48_1121 SG48_RS05760 1164367 1164909 + hypothetical protein gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05760 SG48_RS05765 SG48_1122 SG48_RS05765 1165309 1166613 + NADH dehydrogenase gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05765 SG48_RS05770 SG48_1123 SG48_RS05770 1166823 1167362 + hypothetical protein gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05770 SG48_RS05775 SG48_1124 SG48_RS05775 1167424 1168056 - transcriptional regulator gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05775 SG48_RS05780 SG48_1125 SG48_RS05780 1168297 1168554 + multiple stress resistance protein BhsA gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05780 SG48_RS05785 SG48_1126 SG48_RS05785 1168636 1169595 - peptidoglycan-binding protein LysM gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05785 SG48_RS05790 SG48_1127 SG48_RS05790 1169742 1173188 - transcription-repair-coupling factor gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05790 SG48_RS05795 SG48_1128 SG48_RS05795 1173316 1174389 - hypothetical protein gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05795 SG48_RS05800 SG48_1129 SG48_RS05800 1174651 1175850 + lipoprotein-releasing system protein LolC part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05800 SG48_RS05805 SG48_1130 lolD lolD 1175843 1176544 + lipoprotein-releasing system ATP-binding protein LolD outer membrane specific%3B part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05805 SG48_RS05810 SG48_1131 SG48_RS05810 1176544 1177788 + lipoprotein-releasing system protein LolE part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05810 SG48_RS05815 SG48_1132 SG48_RS05815 1177817 1178728 + N-acetyl-D-glucosamine kinase catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05815 SG48_RS05820 SG48_1133 SG48_RS05820 1178744 1179583 + NAD-dependent deacetylase Modulates the activities of several enzymes which are inactive in their acetylated form gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05820 SG48_RS05825 SG48_1134 SG48_RS05825 1179703 1180491 - hypothetical protein gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05825 SG48_RS05830 SG48_1135 SG48_RS05830 1180488 1180949 - hypothetical protein gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05830 SG48_RS05835 SG48_1136 potD potD 1181007 1182053 - spermidine/putrescine-binding periplasmic protein can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotD is a periplasmic component that binds the substrate gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05835 SG48_RS05840 SG48_1137 potC potC 1182050 1182844 - spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotC is a membrane component gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05840 SG48_RS05845 SG48_1138 potB potB 1182841 1183698 - spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotB is a membrane component gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05845 SG48_RS05850 SG48_1139 potA potA 1183682 1184818 - Fe3+/spermidine/putrescine ABC transporter ATP-binding protein functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport%3B PotA is the membrane-associated ATPase gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05850 SG48_RS05855 SG48_RS05855 SG48_RS05855 1184797 1185012 - hypothetical protein gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05855 SG48_RS05860 SG48_1140 SG48_RS05860 1185068 1186294 + peptidase T gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05860 SG48_RS05865 SG48_1141 SG48_RS05865 1186343 1187464 - 50S ribosomal protein L16 arginine hydroxylase gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05865 SG48_RS05870 SG48_1142 SG48_RS05870 1187540 1189000 - sensor protein PhoQ gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05870 SG48_RS05875 SG48_1143 SG48_RS05875 1189000 1189671 - two-component system response regulator response regulator in two-component regulatory system with PhoQ%3B involved in magnesium starvation and stress gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05875 SG48_RS05880 SG48_1144 SG48_RS05880 1189840 1191210 - adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05880 SG48_RS05885 SG48_1145 SG48_RS05885 1191214 1191855 - lysogenization regulator HflD%3B UPF0274%3B in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein%3B in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05885 SG48_RS05890 SG48_1146 mnmA mnmA 1191891 1192997 - tRNA-specific 2-thiouridylase MnmA catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05890 SG48_RS05895 SG48_1147 SG48_RS05895 1193051 1193512 - phosphatase gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05895 SG48_RS05900 SG48_1148 SG48_RS05900 1193522 1194175 - ribosomal large subunit pseudouridine synthase E catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05900 SG48_RS05905 SG48_1149 SG48_RS05905 1194347 1195597 + isocitrate dehydrogenase Converts isocitrate to alpha ketoglutarate gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05905 SG48_RS05910 SG48_1150 SG48_RS05910 1196091 1196756 - e14 prophage%3B SAM-dependent methyltransferase gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05910 SG48_RS05915 SG48_1151 SG48_RS05915 1196757 1197452 - membrane protein gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05915 SG48_RS05920 SG48_1152 SG48_RS05920 1197919 1198812 + bacteriophage T4 late gene expression-blocking protein gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05920 SG48_RS05925 SG48_1153 SG48_RS05925 1198903 1200030 - integrase gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05925 SG48_RS05930 SG48_1154 SG48_RS05930 1200011 1200256 - excisionase-like protein from lambdoid prophage 14 gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05930 SG48_RS05935 SG48_1156 SG48_RS05935 1201000 1201308 - e14 prophage%3B uncharacterized protein gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05935 SG48_RS05940 SG48_1157 SG48_RS05940 1201483 1202157 - e14 prophage%3B repressor protein phage e14 gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05940 SG48_RS05945 SG48_1158 SG48_RS05945 1202248 1202448 + transcriptional regulator gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05945 SG48_RS05950 SG48_1159 SG48_RS05950 1202492 1203049 + transcriptional regulator gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05950 SG48_RS05955 SG48_1160 SG48_RS05955 1203046 1203384 + e14 prophage%3B uncharacterized protein gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05955 SG48_RS05960 SG48_RS05960 SG48_RS05960 1203394 1204761 + hypothetical protein gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05960 SG48_RS05965 SG48_1163 SG48_RS05965 1204773 1204955 + e14 prophage%3B uncharacterized protein gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05965 SG48_RS05970 SG48_RS05970 SG48_RS05970 1204955 1205428 + hypothetical protein gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05970 SG48_RS05975 SG48_RS05975 SG48_RS05975 1205355 1206146 + hypothetical protein gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05975 SG48_RS05980 SG48_1166 SG48_RS05980 1206137 1206721 + phage tail protein gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05980 SG48_RS05985 SG48_1167 SG48_RS05985 1206725 1207354 + e14 prophage%3B uncharacterized protein gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05985 SG48_RS05990 SG48_1168 SG48_RS05990 1207356 1207769 + e14 prophage%3B uncharacterized protein gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05990 SG48_RS05995 SG48_1169 SG48_RS05995 1207741 1208343 - Tail fiber assembly protein homolog from lambdoid prophage e14 gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS05995 SG48_RS06000 SG48_RS06000 SG48_RS06000 1208343 1208879 - tail fiber protein gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06000 SG48_RS06005 SG48_1171 SG48_RS06005 1208909 1209463 + DNA-invertase from lambdoid prophage e14 gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06005 SG48_RS06010 SG48_1172 SG48_RS06010 1209570 1210403 + 5-methylcytosine-specific restriction enzyme A gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06010 SG48_RS06015 SG48_1174 SG48_RS06015 1210904 1211227 - anti-adapter protein IraM interacts RssB preventing the degradation of the stress sigma factor RpoS gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06015 SG48_RS06020 SG48_RS06020 SG48_RS06020 1211764 1211874 - hypothetical protein gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06020 SG48_RS06025 SG48_1175 SG48_RS06025 1211927 1212331 - DUF1398 domain-containing protein gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06025 SG48_RS06030 SG48_1176 SG48_RS06030 1212552 1213283 - transcriptional regulator gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06030 SG48_RS06035 SG48_1177 SG48_RS06035 1213488 1214699 - blue light- and temperature-regulated antirepressor BluF gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06035 SG48_RS06040 SG48_1178 SG48_RS06040 1215013 1215249 + two-component-system connector protein YcgZ gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06040 SG48_RS06045 SG48_1179 SG48_RS06045 1215292 1215564 + two-component-system connector protein YmgA gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06045 SG48_RS06050 SG48_1180 SG48_RS06050 1215593 1215859 + RcsB connector protein for regulation of biofilm and acid-resistance gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06050 SG48_RS06055 SG48_1181 SG48_RS06055 1215972 1216220 + Blue light%2C low temperature and stress induced protein gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06055 SG48_RS06060 SG48_1182 SG48_RS06060 1216552 1218075 + cyclic-di-GMP phosphodiesterase gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06060 SG48_RS06065 SG48_1183 SG48_RS06065 1218207 1218425 + hypothetical protein gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06065 SG48_RS06070 SG48_RS06070 SG48_RS06070 1218430 1218558 - hypothetical protein gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06070 SG48_RS06085 SG48_1185 SG48_RS06085 1221529 1221858 - hypothetical protein gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06085 SG48_RS06090 SG48_1186 SG48_RS06090 1221868 1222212 - hypothetical protein gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06090 SG48_RS06095 SG48_1187 SG48_RS06095 1222214 1222387 - hypothetical protein gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06095 SG48_RS06100 SG48_RS06100 SG48_RS06100 1222806 1223131 + ATPase gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06100 SG48_RS06105 SG48_1190 minE minE 1223503 1223769 - cell division topological specificity factor works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06105 SG48_RS06110 SG48_1191 SG48_RS06110 1223773 1224585 - septum site-determining protein MinD ATPase%3B with MinC inhibits cell division by blocking formation of the polar Z ring septums gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06110 SG48_RS06115 SG48_1192 minC minC 1224609 1225304 - septum site-determining protein MinC blocks the formation of polar Z-ring septums gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06115 SG48_RS06120 SG48_1193 SG48_RS06120 1225824 1226192 + hypothetical protein gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06120 SG48_RS06125 SG48_1194 SG48_RS06125 1226295 1226696 - inhibitor of g-type lysozyme gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06125 SG48_RS06130 SG48_RS06130 SG48_RS06130 1226680 1226895 + hypothetical protein gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06130 SG48_RS06135 SG48_1195 SG48_RS06135 1226905 1227231 + hypothetical protein gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06135 SG48_RS06140 SG48_1196 SG48_RS06140 1227303 1227962 + isomerase/hydrolase gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06140 SG48_RS06145 SG48_1197 SG48_RS06145 1228039 1228500 + hypothetical protein gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06145 SG48_RS06150 SG48_1198 hlyE hlyE 1228707 1229618 - hemolysin E%2C chromosomal Acts by forming a pore-like structure upon contact with mammalian cells gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06150 SG48_RS06155 SG48_1199 SG48_RS06155 1229991 1230410 + protein UmuD binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06155 SG48_RS06160 SG48_1200 SG48_RS06160 1230410 1231678 + protein UmuC binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06160 SG48_RS06165 SG48_1201 SG48_RS06165 1231724 1232254 - disulfide bond formation protein B disulfide oxidoreductase%3B integral membrane protein%3B required for perioplasmic disulfide bond formation%3B oxidizes DsbA protein gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06165 SG48_RS06170 SG48_1202 nhaB nhaB 1232400 1233941 - Na+/H+ antiporter NhaB involved in regulation of intracellular pH under alkaline conditions gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06170 SG48_RS06175 SG48_1203 SG48_RS06175 1234162 1234881 + fatty acid metabolism regulator protein Multifunctional regulator of fatty acid metabolism gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06175 SG48_RS06180 SG48_1204 SG48_RS06180 1234933 1236465 - SpoVR family stationary phase gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06180 SG48_RS06185 SG48_1205 SG48_RS06185 1236795 1238093 + D-amino acid dehydrogenase catalyzes the oxidative deamination of D-amino acids gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06185 SG48_RS06190 SG48_1206 SG48_RS06190 1238103 1239173 + alanine racemase catabolic converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06190 SG48_RS06195 SG48_1207 cvrA cvrA 1239559 1241295 - K+/H+ antiporter NhaP2 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter%3B can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06195 SG48_RS06200 SG48_1208 ldcA ldcA 1241390 1242304 - murein tetrapeptide carboxypeptidase catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06200 SG48_RS06205 SG48_1209 emtA emtA 1242404 1243015 + murein transglycosylase catalyzes the cleavage of 1-4 beta-glycoside linkaged between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06205 SG48_RS06210 SG48_1210 SG48_RS06210 1243017 1243751 - flagellar brake protein YcgR gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06210 SG48_RS06215 SG48_1211 SG48_RS06215 1243952 1244206 + hypothetical protein gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06215 SG48_RS06220 SG48_1212 SG48_RS06220 1244384 1244824 + hypothetical protein gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06220 SG48_RS06225 SG48_1213 treA treA 1244903 1246600 - periplasmic trehalase periplasmic%3B catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06225 SG48_RS06230 SG48_1214 SG48_RS06230 1246920 1248338 - dihydroxyacetone kinase subunit DhaM phosphotransferaese subunit%3B phosphorylates dihydroxyacetone along with DhaK/DhaL gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06230 SG48_RS06235 SG48_1215 SG48_RS06235 1248349 1248981 - dihydroxyacetone kinase subunit DhaL with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06235 SG48_RS06240 SG48_1216 SG48_RS06240 1248992 1250062 - dihydroxyacetone kinase subunit DhaK with DhaL and DhaM forms dihydroxyacetone kinase%2C which is responsible for phosphorylating dihydroxyacetone%3B DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06240 SG48_RS06245 SG48_1217 SG48_RS06245 1250290 1252209 + dihydroxyacetone kinase subunit DhaR Positively regulates the dhaKLM operon from a sigma-70 promoter gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06245 SG48_RS06250 SG48_1218 SG48_RS06250 1252309 1255176 - adhesin gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06250 SG48_RS06255 SG48_RS06255 SG48_RS06255 1255521 1255700 + hypothetical protein gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06255 SG48_RS06260 SG48_1219 ychF ychF 1255945 1257036 - ribosome-binding ATPase YchF EngD%3B translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06260 SG48_RS06265 SG48_1220 SG48_RS06265 1257153 1257737 - peptidyl-tRNA hydrolase gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06265 SG48_RS06270 SG48_1221 SG48_RS06270 1258015 1258293 + membrane protein YchH%3B transcription activated by CRP (cyclic AMP receptor protein)%2C a global transcription factor involved in regulation of metabolism in enteric bacteria%3B ychH presents a class II promoter to bind CRP%3B unknown function gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06270 SG48_RS06275 SG48_1222 SG48_RS06275 1258348 1260000 - transporter role in sulfate transport across the inner membrane%3B member of the SulP family of sulfate transporters%3B seems to mediate transport via sulfate/proton symport gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06275 SG48_RS06280 SG48_1223 SG48_RS06280 1260152 1261099 - ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06280 SG48_RS06285 SG48_1224 SG48_RS06285 1261250 1262101 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06285 SG48_RS06290 SG48_1225 lolB lolB 1262101 1262724 - outer membrane lipoprotein LolB Incorporates lipoproteins in the outer membrane after they are released by the LolA protein gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06290 SG48_RS06295 SG48_1226 hemA hemA 1262938 1264194 + glutamyl-tRNA reductase catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH%3B the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid%3B functions in porphyrin (tetrapyrroles) biosynthesis%3B the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06295 SG48_RS06300 SG48_1227 prfA prfA 1264236 1265318 + peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06300 SG48_RS06305 SG48_1228 SG48_RS06305 1265318 1266151 + release factor glutamine methyltransferase HemK%3B PrmC%3B transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06305 SG48_RS06310 SG48_1229 SG48_RS06310 1266148 1266540 + protein sirB2 gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06310 SG48_RS06315 SG48_1230 SG48_RS06315 1266544 1267353 + protein sirB1 gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06315 SG48_RS06320 SG48_1231 SG48_RS06320 1267389 1268243 + 2-dehydro-3-deoxyphosphooctonate aldolase catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06320 SG48_RS06325 SG48_RS06325 SG48_RS06325 1268392 1268526 - hypothetical protein gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06325 SG48_RS06330 SG48_RS06330 SG48_RS06330 1268927 1269061 - hypothetical protein gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06330 SG48_RS06335 SG48_RS06335 SG48_RS06335 1269462 1269596 - hypothetical protein gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06335 SG48_RS06340 SG48_1238 SG48_RS06340 1269973 1271073 - sodium/proton antiporter ChaA gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06340 SG48_RS06345 SG48_1239 chaB chaB 1271343 1271573 + cation transport regulator ChaB in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA%3B has weak affinity for calcium and magnesium ions gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06345 SG48_RS06350 SG48_1240 SG48_RS06350 1271731 1272426 + glutathione-specific gamma-glutamylcyclotransferase gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06350 SG48_RS06355 SG48_1241 SG48_RS06355 1272470 1272823 - hypothetical protein gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06355 SG48_RS06360 SG48_1242 SG48_RS06360 1273008 1274402 + invasin gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06360 SG48_RS06365 SG48_1243 SG48_RS06365 1274403 1275053 - transcriptional regulator two-component response regulator NarL%3B phosphorylated by NarQ%3B activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06365 SG48_RS06370 SG48_1244 SG48_RS06370 1275046 1276842 - nitrate/nitrite two-component system sensor histidine kinase gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06370 SG48_RS06375 SG48_RS06375 SG48_RS06375 1276868 1277086 + hypothetical protein gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06375 SG48_RS06380 SG48_1245 SG48_RS06380 1277181 1278572 + nitrate/nitrite transporter NarK involved in the transport of nitrate and nitrite gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06380 SG48_RS06385 SG48_1246 narZ narZ 1279088 1282831 + respiratory nitrate reductase 1 alpha chain with NarYV catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli%3B expression of nitrate reductase Z is not dependent on nitrate levels gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06385 SG48_RS06390 SG48_1247 narH narH 1282828 1284366 + nitrate reductase subunit beta with NarGJI catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06390 SG48_RS06395 SG48_1248 SG48_RS06395 1284363 1285073 + nitrate reductase molybdenum cofactor assembly chaperone NarJ delta subunit of nitrate reductase 1%3B chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1 gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06395 SG48_RS06400 SG48_1249 narI narI 1285073 1285750 + respiratory nitrate reductase subunit gamma with NarGJH catalyzes the reduction of nitrate%3B the gamma subunit localizes NarGHI to the membrane%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06400 SG48_RS06405 SG48_RS06405 SG48_RS06405 1285933 1286208 + hypothetical protein gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06405 SG48_RS06410 SG48_1252 SG48_RS06410 1286468 1286552 - tRNA-Tyr tRNA gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06410 SG48_RS06415 SG48_1253 SG48_RS06415 1286762 1286846 - tRNA-Tyr tRNA gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06415 SG48_RS06420 SG48_1254 SG48_RS06420 1287006 1287848 - formyltetrahydrofolate deformylase gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06420 SG48_RS06425 SG48_1255 SG48_RS06425 1287898 1288356 - hypothetical protein gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06425 SG48_RS06430 SG48_1256 SG48_RS06430 1288469 1289374 + NTE family protein RssA gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06430 SG48_RS06435 SG48_1257 SG48_RS06435 1289466 1290479 + regulator of RpoS gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06435 SG48_RS06440 SG48_1258 SG48_RS06440 1290681 1291589 + UTP--glucose-1-phosphate uridylyltransferase together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase%2C an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate%3B regulates cellular levels of UDP-glucose gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06440 SG48_RS06445 SG48_1259 SG48_RS06445 1291733 1292146 - DNA-binding protein H-NS gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06445 SG48_RS06450 SG48_1260 SG48_RS06450 1292751 1293368 + thymidine kinase catalyzes the formation of thymidine 5'-phosphate from thymidine gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06450 SG48_RS06455 SG48_RS06455 SG48_RS06455 1293650 1294240 - transposase gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06455 SG48_RS06460 SG48_RS06460 SG48_RS06460 1294185 1294501 - hypothetical protein gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06460 SG48_RS06465 SG48_1262 SG48_RS06465 1294670 1297345 - aldehyde-alcohol dehydrogenase gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06465 SG48_RS06470 SG48_1263 SG48_RS06470 1297822 1298469 + hypothetical protein gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06470 SG48_RS06475 SG48_1264 SG48_RS06475 1299207 1300838 + periplasmic oligopeptide-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06475 SG48_RS06480 SG48_1265 oppB oppB 1300924 1301844 + peptide ABC transporter permease gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06480 SG48_RS06485 SG48_1266 SG48_RS06485 1301859 1302767 + peptide ABC transporter permease with OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06485 SG48_RS06490 SG48_1267 oppD oppD 1302779 1303792 + oligopeptide transport ATP-binding protein OppD gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06490 SG48_RS06495 SG48_1268 SG48_RS06495 1303789 1304793 + oligopeptide transport ATP-binding protein OppF with OppABCD is involved in the transport of oligopeptides%3B OppF and OppD are ATP-binding proteins gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06495 SG48_RS06500 SG48_1269 SG48_RS06500 1304846 1305175 - hypothetical protein highly acidic protein%3B the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi)%3B binds heat-unstable protein (HU-alpha) which is a histone-like protein gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06500 SG48_RS06505 SG48_1270 cls cls 1305210 1306670 - cardiolipin synthase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06505 SG48_RS06510 SG48_RS06510 SG48_RS06510 1306702 1306986 + hypothetical protein gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06510 SG48_RS06515 SG48_1272 SG48_RS06515 1307041 1308294 - voltage-gated potassium channel Kch gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06515 SG48_RS06520 SG48_1273 SG48_RS06520 1308594 1308890 - hypothetical protein unknown function%3B YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase%2C but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06520 SG48_RS06525 SG48_1274 SG48_RS06525 1309114 1309833 + protein TonB membrane spanning protein in TonB-ExbB-ExbD complex%3B transduces proton motive force of the cytoplasmic membrane to outer membrane transporters%3B involved in the transport of ron-siderophore complexes%2C vitamin B12 and colicins gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06525 SG48_RS06530 SG48_1275 SG48_RS06530 1309873 1310271 - acyl-CoA thioester hydrolase YciA gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06530 SG48_RS06535 SG48_1276 SG48_RS06535 1310376 1310915 - intracellular septation protein A Involved in cell division%3B probably involved in intracellular septation gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06535 SG48_RS06540 SG48_1277 SG48_RS06540 1310945 1311688 - hypothetical protein gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06540 SG48_RS06545 SG48_1278 SG48_RS06545 1312045 1312683 + outer membrane protein W receptor for colicin S4 gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06545 SG48_RS06550 SG48_1279 SG48_RS06550 1312743 1313249 - hypothetical protein gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06550 SG48_RS06555 SG48_1280 SG48_RS06555 1313295 1313795 - hypothetical protein gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06555 SG48_RS06560 SG48_1281 SG48_RS06560 1313881 1314060 - hypothetical protein gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06560 SG48_RS06565 SG48_1282 SG48_RS06565 1314441 1315247 - tryptophan synthase subunit alpha gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06565 SG48_RS06570 SG48_1283 SG48_RS06570 1315247 1316440 - tryptophan synthase subunit beta catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06570 SG48_RS06575 SG48_1284 SG48_RS06575 1316452 1317810 - phosphoribosylanthranilate isomerase monomeric bifunctional protein%3B functions in tryptophan biosynthesis pathway%3B phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06575 SG48_RS06580 SG48_1285 SG48_RS06580 1317814 1319409 - bifunctional protein TrpGD bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase%3B TrpD%3B forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine%3B also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate%3B functions in tryptophan biosynthesis gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06580 SG48_RS06585 SG48_1286 SG48_RS06585 1319409 1320971 - anthranilate synthase component 1 gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06585 SG48_RS06590 SG48_1288 SG48_RS06590 1321245 1322126 + PHP domain-containing protein YciV gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06590 SG48_RS06595 SG48_1289 SG48_RS06595 1322123 1322743 + RNA binding protein gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06595 SG48_RS06600 SG48_1290 SG48_RS06600 1322771 1324666 + hypothetical protein gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06600 SG48_RS06605 SG48_1291 SG48_RS06605 1324877 1325752 + ribosomal large subunit pseudouridine synthase B catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06605 SG48_RS06610 SG48_1292 SG48_RS06610 1325792 1326382 - cob(I)yrinic acid a%2Cc-diamide adenosyltransferase catalyzes the formation of adenosylcobalamide from cobinamide and the formation of coenzyme B12 from cob(I)alamin gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06610 SG48_RS06615 SG48_1293 SG48_RS06615 1326379 1327137 - oxoacyl-ACP reductase gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06615 SG48_RS06620 SG48_RS06620 SG48_RS06620 1327181 1327345 - hypothetical protein gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06620 SG48_RS06625 SG48_1294 SG48_RS06625 1327357 1328406 + protease multicopy suppressor of htrA(degP) gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06625 SG48_RS06630 SG48_1295 SG48_RS06630 1328442 1328693 - hypothetical protein gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06630 SG48_RS06635 SG48_RS06635 SG48_RS06635 1328798 1328950 + hypothetical protein gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06635 SG48_RS06640 SG48_1296 SG48_RS06640 1329073 1331670 + DNA topoisomerase 1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06640 SG48_RS06645 SG48_1297 cysB cysB 1331880 1332854 + transcriptional regulator LysR-type transcriptional regulator%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon%3B autoregulates expression%3B crystal structure of Klebsiella aerogenes showed tetramer formation gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06645 SG48_RS06650 SG48_1298 SG48_RS06650 1333185 1333313 + hypothetical protein gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06650 SG48_RS06655 SG48_1299 SG48_RS06655 1333316 1333483 + hypothetical protein gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06655 SG48_RS06660 SG48_RS06660 SG48_RS06660 1333557 1333682 - hypothetical protein gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06660 SG48_RS06665 SG48_1300 SG48_RS06665 1333856 1336531 + aconitate hydratase 1 Catalyzes the conversion of citrate to isocitrate gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06665 SG48_RS06670 SG48_1301 ribA ribA 1336595 1337185 - GTP cyclohydrolase-2 catalyzes the conversion of GTP to formate and 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06670 SG48_RS06675 SG48_1302 SG48_RS06675 1337355 1338119 + phosphatidylglycerophosphatase B gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06675 SG48_RS06680 SG48_1303 SG48_RS06680 1338268 1338576 + LPS assembly protein A gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06680 SG48_RS06685 SG48_1304 SG48_RS06685 1338583 1339752 + LPS assembly protein B gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06685 SG48_RS06690 SG48_1305 SG48_RS06690 1339946 1340683 + orotidine 5'-phosphate decarboxylase gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06690 SG48_RS06695 SG48_1306 SG48_RS06695 1340683 1341009 + initiation factor function involved in start site selection during the initiation of translation gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06695 SG48_RS06700 SG48_1307 SG48_RS06700 1341135 1341353 - osmotically-inducible lipoprotein B gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06700 SG48_RS06705 SG48_1308 SG48_RS06705 1341622 1342371 - DeoR family transcriptional regulator gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06705 SG48_RS06710 SG48_1309 SG48_RS06710 1342461 1342634 - hypothetical protein gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06710 SG48_RS06715 SG48_1310 SG48_RS06715 1342782 1344767 - cyclic di-GMP phosphodiesterase Gmr c-di-GMP phosphodiesterase%3B probably degrades signalling molecule c-di-GMP gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06715 SG48_RS06720 SG48_1311 SG48_RS06720 1344821 1344925 + hypothetical protein gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06720 SG48_RS06725 SG48_1312 SG48_RS06725 1345003 1346937 - exoribonuclease 2 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06725 SG48_RS06730 SG48_1313 SG48_RS06730 1347005 1348132 - oxidoreductase gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06730 SG48_RS06735 SG48_1314 SG48_RS06735 1348276 1349064 - enoyl-ACP reductase [NADH] Catalyzes a key regulatory step in fatty acid biosynthesis gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06735 SG48_RS06740 SG48_1315 SG48_RS06740 1349432 1349782 - hypothetical protein gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06740 SG48_RS06745 SG48_1316 SG48_RS06745 1349853 1350659 - peptide transport system ATP-binding protein SapF gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06745 SG48_RS06750 SG48_1317 SG48_RS06750 1350661 1351653 - peptide transport system ATP-binding protein SapD involved in resistance to antimibial peptides gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06750 SG48_RS06755 SG48_1318 SG48_RS06755 1351653 1352543 - peptide ABC transporter permease gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06755 SG48_RS06760 SG48_1319 SG48_RS06760 1352530 1353495 - peptide ABC transporter permease gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06760 SG48_RS06765 SG48_1320 SG48_RS06765 1353492 1355135 - peptide transport periplasmic protein SapA gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06765 SG48_RS06770 SG48_RS06770 SG48_RS06770 1355178 1355378 - hypothetical protein gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06770 SG48_RS06775 SG48_1321 SG48_RS06775 1355448 1355693 - DUF2543 domain-containing protein gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06775 SG48_RS06780 SG48_1322 SG48_RS06780 1355827 1357212 - putrescine importer PuuP gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06780 SG48_RS06785 SG48_1323 SG48_RS06785 1357515 1358933 - gamma-glutamylputrescine synthetase PuuA gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06785 SG48_RS06790 SG48_1324 puuD puuD 1359145 1359909 + gamma-glutamyl-gamma-aminobutyrate hydrolase catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06790 SG48_RS06795 SG48_1325 SG48_RS06795 1359936 1360493 + transcriptional regulator regulates genes involved in putrescine degradation gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06795 SG48_RS06800 SG48_1326 SG48_RS06800 1360768 1362255 + aldehyde dehydrogenase PuuC gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06800 SG48_RS06805 SG48_1327 SG48_RS06805 1362257 1363537 + gamma-glutamylputrescine oxidoreductase catalyzes the formation of gamma-glutamyl-gamma-aminobutyraldehyde from gamma-glutamylputrescine gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06805 SG48_RS06810 SG48_1328 SG48_RS06810 1363575 1364840 + 4-aminobutyrate aminotransferase PuuE catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06810 SG48_RS06815 SG48_1329 pspF pspF 1364960 1365937 - psp operon transcriptional activator transcriptional activator for pspABCE which are induced in response to phage proteins%2C membrane altering stresses%2C and impaired proton expor gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06815 SG48_RS06820 SG48_1330 SG48_RS06820 1366104 1366772 + phage shock protein A involved in maintaining membrane potential under membrane stress conditions%3B also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06820 SG48_RS06825 SG48_1331 pspB pspB 1366826 1367050 + phage shock protein B DNA-binding transcriptional regulator%3B acts together with PspC to induce psp operon during infection with phage%2C exposure to ethanol or osmotic shock%3B forms a complex with PspA and C%3B PspC is required for PspAB binding gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06825 SG48_RS06830 SG48_1332 SG48_RS06830 1367050 1367409 + phage shock protein C with PsbB forms toxin/antitoxin pair%3B activates the psp operon in response to phage infection%2C exposure to ethanol or osmotic shock gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06830 SG48_RS06835 SG48_1333 SG48_RS06835 1367418 1367639 + phage shock protein D gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06835 SG48_RS06840 SG48_1334 SG48_RS06840 1367714 1368028 + thiosulfate sulfurtransferase PspE rhodanese%3B catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06840 SG48_RS06845 SG48_1335 SG48_RS06845 1368241 1369920 + alpha amylase catalytic domain family protein gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06845 SG48_RS06850 SG48_1336 SG48_RS06850 1369934 1371226 + sugar ABC transporter substrate-binding protein gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06850 SG48_RS06855 SG48_1337 SG48_RS06855 1371247 1372128 + ABC transporter permease gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06855 SG48_RS06860 SG48_1338 SG48_RS06860 1372115 1372957 + ABC transporter permease gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06860 SG48_RS06865 SG48_1339 SG48_RS06865 1372988 1374040 + Zn-dependent NAD(P)-binding oxidoreductase gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06865 SG48_RS06870 SG48_1340 SG48_RS06870 1374059 1374847 + hypothetical protein gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06870 SG48_RS06875 SG48_1341 SG48_RS06875 1374857 1375912 + NADH-binding oxidoreductase gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06875 SG48_RS06880 SG48_1342 SG48_RS06880 1375909 1378176 + family 65 glycosyl hydrolase gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06880 SG48_RS06885 SG48_1343 SG48_RS06885 1378173 1378832 + beta-phosphoglucomutase catalyzes the interconversion of beta-D-glucose 6-phosphate to beta-D-glucose 1-phosphate gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06885 SG48_RS06890 SG48_RS06890 SG48_RS06890 1378846 1379927 + sugar ABC transporter ATP-binding protein gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06890 SG48_RS06895 SG48_1345 SG48_RS06895 1379972 1380877 + outer membrane protein G gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06895 SG48_RS06900 SG48_1346 SG48_RS06900 1380988 1381986 - LacI family transcriptional regulator gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06900 SG48_RS06905 SG48_1347 SG48_RS06905 1382142 1383539 + DUF463 domain-containing protein gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06905 SG48_RS06910 SG48_1348 SG48_RS06910 1383536 1384597 + hypothetical protein gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06910 SG48_RS06915 SG48_1349 SG48_RS06915 1384745 1386286 + transcriptional regulator regulates genes involved in the biosynthesis and transport of aromatic amino acids gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06915 SG48_RS06920 SG48_1350 tpx tpx 1386330 1386836 - thiol peroxidase antioxidant activity%3B thioredoxin-dependent thiol peroxidase%3B forms homodimers in solution%3B shows substrate specificity to alkyl hydroperoxides%3B periplasmic protein gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06920 SG48_RS06925 SG48_1351 SG48_RS06925 1386955 1387920 + L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-alanyl-D-glutamate to L-alanyl-L-glutamate gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06925 SG48_RS06930 SG48_1352 SG48_RS06930 1387895 1388623 - protein MpaA gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06930 SG48_RS06935 SG48_RS06935 SG48_RS06935 1388705 1388887 - hypothetical protein gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06935 SG48_RS06940 SG48_1355 SG48_RS06940 1388958 1389878 - S9 homolog non-peptidase gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06940 SG48_RS06945 SG48_1356 SG48_RS06945 1390016 1390915 + transcriptional regulator gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06945 SG48_RS06950 SG48_RS06950 SG48_RS06950 1391004 1391129 + hypothetical protein gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06950 SG48_RS06955 SG48_1357 SG48_RS06955 1391252 1392865 + periplasmic murein peptide-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06955 SG48_RS06960 SG48_1358 SG48_RS06960 1392916 1393947 - low conductance mechanosensitive channel YnaI gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06960 SG48_RS06965 SG48_1359 SG48_RS06965 1394137 1395117 + transposase gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06965 SG48_RS06970 SG48_1360 SG48_RS06970 1395390 1395647 + DUF2534 domain-containing protein gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06970 SG48_RS06975 SG48_1361 SG48_RS06975 1395697 1396647 - universal stress protein E with UspC and UspD is involved in resistance to UV irradiation gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06975 SG48_RS06980 SG48_1362 SG48_RS06980 1396799 1397551 - fumarate and nitrate reduction regulatory protein Global transcription factor that controls the expression of over 100 target genes in response to anoxia gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06980 SG48_RS06985 SG48_1363 SG48_RS06985 1397746 1398261 - methylated-DNA--protein-cysteine methyltransferase gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06985 SG48_RS06990 SG48_1364 SG48_RS06990 1398272 1399798 - p-aminobenzoyl-glutamate transporter gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06990 SG48_RS06995 SG48_RS06995 SG48_RS06995 1399728 1399922 - hypothetical protein gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS06995 SG48_RS07000 SG48_1365 SG48_RS07000 1399835 1401280 - p-aminobenzoyl-glutamate hydrolase subunit B gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07000 SG48_RS07005 SG48_1366 SG48_RS07005 1401280 1402590 - p-aminobenzoyl-glutamate hydrolase subunit A gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07005 SG48_RS07010 SG48_1367 SG48_RS07010 1402766 1403674 + transcriptional regulator gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07010 SG48_RS07015 SG48_RS07015 SG48_RS07015 1403746 1403856 - glutamate decarboxylase gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07015 SG48_RS07020 SG48_1369 SG48_RS07020 1404004 1404567 + DNA endonuclease SmrA gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07020 SG48_RS07025 SG48_1370 SG48_RS07025 1404588 1405820 - diguanylate cyclase gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07025 SG48_RS07030 SG48_1371 zntB zntB 1406075 1407058 + zinc transporter ZntB gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07030 SG48_RS07035 SG48_RS07035 SG48_RS07035 1407333 1407506 + hypothetical protein gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07035 SG48_RS07040 SG48_1373 SG48_RS07040 1407536 1408909 + ATP-dependent RNA helicase DbpA exhibits an RNA-dependent ATPase activity%2C specifically stimulated by bacterial 23S rRNA gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07040 SG48_RS07045 SG48_1374 SG48_RS07045 1409038 1409973 - tRNA 2-thiocytidine biosynthesis protein TtcA TtcA%3B YdaO%3B catalyzes the thiolation of cytosine 32 in specific tRNAs%3B forms 2-thiocytidine (s(2)C) gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07045 SG48_RS07050 SG48_RS07050 SG48_RS07050 1410025 1410165 - integrase gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07050 SG48_RS07055 SG48_1376 SG48_RS07055 1411262 1411477 - Rac prophage%3B conserved protein gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07055 SG48_RS07060 SG48_1377 SG48_RS07060 1411556 1411765 - double-strand break reduction protein Rac prophage gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07060 SG48_RS07065 SG48_1378 lar lar 1411758 1411952 - restriction alleviation and modification enhancement protein seems to be involved in restriction alleviation and enhancement of modification by EcoKI%2C but not in restriction alleviation of type III restriction systems%3B Rac prophage gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07065 SG48_RS07070 SG48_1379 recT recT 1412009 1412818 - DNA recombination protein RecT gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07070 SG48_RS07075 SG48_1380 SG48_RS07075 1412811 1415411 - exodeoxyribonuclease 8 The RecE (also known as exonuclease VIII) pathway is an alternative pathway for the initiation of homologous recombination in Escherichia coli. The RecE pathway is activated in recB%2C recC sbcA (suppressors of recB and recC) mutants. Activation of the RecE pathway results in the production of at least two phage proteins relevant for recombinational repair. RecE is a duplex DNA-specific exonuclease which produces 3' overhangs in duplex DNA by preferentially degrading the 5'-ending strands. Recombinational repair of E.coli chromosomal DNA involves as well other proteins: RecA%2C RecF%2C RecJ%2C RecO%2C RecR%2C and RuvC. gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07075 SG48_RS07080 SG48_1381 SG48_RS07080 1415513 1415788 - protein RacC Rac prophage hypothetical protein gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07080 SG48_RS07085 SG48_1382 SG48_RS07085 1415863 1416039 - hypothetical protein gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07085 SG48_RS07090 SG48_1383 kil kil 1416033 1416254 - killing protein KilR Rac prophage Kil protein%3B Kil overexpression leads to morphological defects and inhibits cell division gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07090 SG48_RS07095 SG48_1384 SG48_RS07095 1416696 1417184 + superinfection exclusion protein B gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07095 SG48_RS07100 SG48_1387 SG48_RS07100 1417790 1418266 - Rac prophage repressor gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07100 SG48_RS07105 SG48_1388 SG48_RS07105 1418390 1418686 + transcriptional regulator gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07105 SG48_RS07110 SG48_1389 SG48_RS07110 1418709 1419131 + Rac prophage%3B uncharacterized protein gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07110 SG48_RS07115 SG48_1390 SG48_RS07115 1419144 1420001 + Rac prophage%3B conserved protein gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07115 SG48_RS07120 SG48_1391 SG48_RS07120 1420008 1420754 + Rac prophage%3B DNA replication protein gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07120 SG48_RS07125 SG48_RS07125 SG48_RS07125 1420777 1421229 + hypothetical protein gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07125 SG48_RS07130 SG48_RS07130 SG48_RS07130 1421220 1421669 + endopeptidase gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07130 SG48_RS07135 SG48_1395 SG48_RS07135 1421807 1423264 + Trk system potassium uptake protein TrkG gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07135 SG48_RS07140 SG48_1396 SG48_RS07140 1423402 1423665 + Rac prophage%3B conserved protein gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07140 SG48_RS07145 SG48_RS07145 SG48_RS07145 1423646 1424005 + hypothetical protein gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07145 SG48_RS07150 SG48_RS07150 SG48_RS07150 1424113 1424313 + hypothetical protein gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07150 SG48_RS07155 SG48_RS07155 SG48_RS07155 1424479 1425507 + hypothetical protein gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07155 SG48_RS07160 SG48_RS07160 SG48_RS07160 1425414 1425629 + enterobacterial Ail/Lom family protein gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07160 SG48_RS07165 SG48_1400 SG48_RS07165 1425771 1426751 - transposase gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07165 SG48_RS07170 SG48_RS07170 SG48_RS07170 1426821 1427009 + enterobacterial Ail/Lom family protein gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07170 SG48_RS07175 SG48_RS07175 SG48_RS07175 1427010 1427183 - hypothetical protein gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07175 SG48_RS07180 SG48_RS07180 SG48_RS07180 1427571 1428308 - hypothetical protein gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07180 SG48_RS07185 SG48_RS07185 SG48_RS07185 1428439 1430436 + membrane protein gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07185 SG48_RS07190 SG48_1402 SG48_RS07190 1430436 1431011 + Tail fiber assembly protein homolog from lambdoid prophage Rac gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07190 SG48_RS07195 SG48_1403 SG48_RS07195 1431109 1431699 - Rac prophage%3B site-specific recombinase gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07195 SG48_RS07200 SG48_1404 SG48_RS07200 1432016 1432249 - cold-shock protein gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07200 SG48_RS07205 SG48_1406 SG48_RS07205 1433210 1433644 - universal stress protein F gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07205 SG48_RS07210 SG48_1407 SG48_RS07210 1433785 1434918 - outer membrane protein N allows for ions and hydrophilic solutes to cross the outer membrane gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07210 SG48_RS07215 SG48_1409 SG48_RS07215 1435285 1438809 - pyruvate-flavodoxin oxidoreductase gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07215 SG48_RS07220 SG48_1410 SG48_RS07220 1439083 1439349 + DUF333 domain-containing protein gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07220 SG48_RS07225 SG48_1411 SG48_RS07225 1439346 1439768 - heat-shock protein HslJ gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07225 SG48_RS07230 SG48_1412 SG48_RS07230 1439879 1440868 - lactate dehydrogenase fermentative%3B catalyzes the formationof pyruvate from lactate gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07230 SG48_RS07235 SG48_1413 SG48_RS07235 1441076 1443715 + membrane-anchored protein%2C function unknown gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07235 SG48_RS07240 SG48_1414 SG48_RS07240 1443712 1443897 + lipoprotein gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07240 SG48_RS07245 SG48_1415 SG48_RS07245 1443905 1444231 + DUF1318 domain-containing protein gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07245 SG48_RS07250 SG48_1416 SG48_RS07250 1444403 1445308 - transcriptional activator FeaR activator of genes involved in phenylacetic acid catabolism gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07250 SG48_RS07255 SG48_1417 SG48_RS07255 1445544 1447043 + phenylacetaldehyde dehydrogenase gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07255 SG48_RS07260 SG48_1418 tynA tynA 1447101 1449374 - primary amine oxidase catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07260 SG48_RS07265 SG48_1419 SG48_RS07265 1449622 1451667 - bifunctional protein PaaZ catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07265 SG48_RS07270 SG48_1420 paaA paaA 1451952 1452881 + 1%2C2-phenylacetyl-CoA epoxidase subunit A with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07270 SG48_RS07275 SG48_1421 paaB paaB 1452893 1453180 + 1%2C2-phenylacetyl-CoA epoxidase subunit B with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA%3B involved in phenylacetate degradation gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07275 SG48_RS07280 SG48_1422 SG48_RS07280 1453189 1453935 + 1%2C2-phenylacetyl-CoA epoxidase subunit C gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07280 SG48_RS07285 SG48_1423 SG48_RS07285 1453950 1454447 + 1%2C2-phenylacetyl-CoA epoxidase gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07285 SG48_RS07290 SG48_1424 SG48_RS07290 1454455 1455525 + 1%2C2-phenylacetyl-CoA epoxidase subunit E gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07290 SG48_RS07295 SG48_1425 SG48_RS07295 1455522 1456289 + 2%2C3-dehydroadipyl-CoA hydratase gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07295 SG48_RS07300 SG48_1426 SG48_RS07300 1456289 1457077 + 1%2C2-epoxyphenylacetyl-CoA isomerase Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07300 SG48_RS07305 SG48_1427 SG48_RS07305 1457079 1458506 + 3-hydroxyadipyl-CoA dehydrogenase gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07305 SG48_RS07310 SG48_1428 SG48_RS07310 1458496 1458918 + acyl-CoA thioesterase gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07310 SG48_RS07315 SG48_1429 SG48_RS07315 1458918 1460123 + 3-oxoadipyl-CoA/3-oxo-5%2C6-dehydrosuberyl-CoA thiolase catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07315 SG48_RS07320 SG48_1430 SG48_RS07320 1460150 1461463 + phenylacetate-CoA ligase gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07320 SG48_RS07325 SG48_1431 SG48_RS07325 1461564 1462514 + transcriptional regulator gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07325 SG48_RS07330 SG48_1432 SG48_RS07330 1462496 1463086 + phenylacetic acid degradation protein PaaY involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07330 SG48_RS07335 SG48_RS07335 SG48_RS07335 1463417 1465942 + hypothetical protein gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07335 SG48_RS07340 SG48_1435 SG48_RS07340 1465946 1466851 - integrase gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07340 SG48_RS07345 SG48_1436 SG48_RS07345 1466809 1467174 - transposase represses IS2 gene transcription gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07345 SG48_RS07350 SG48_1437 SG48_RS07350 1467383 1468534 + transposase gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07350 SG48_RS07355 SG48_RS07355 SG48_RS07355 1468715 1472038 + autotransporter subunit beta gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07355 SG48_RS07360 SG48_1438 SG48_RS07360 1472246 1473106 + oxidoreductase gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07360 SG48_RS07365 SG48_1439 SG48_RS07365 1473169 1475475 + hypothetical protein gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07365 SG48_RS07370 SG48_1440 SG48_RS07370 1475646 1476251 + hypothetical protein gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07370 SG48_RS07375 SG48_1441 SG48_RS07375 1476251 1477147 + CDP-diglyceride synthase gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07375 SG48_RS07380 SG48_1442 SG48_RS07380 1477163 1478920 + esterase gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07380 SG48_RS07385 SG48_1443 SG48_RS07385 1478910 1480226 + hypothetical protein gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07385 SG48_RS07390 SG48_1444 SG48_RS07390 1480280 1480885 - FMN-dependent NADH-azoreductase FMN-dependent%3B requires NADH%3B catalyzes the cleavage of azo bond in aromatic azo compounds gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07390 SG48_RS07395 SG48_1445 SG48_RS07395 1481086 1484988 + ATP-dependent RNA helicase HrpA involved in the post-transcriptional processing of the daa operon mRNA%2C which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07395 SG48_RS07400 SG48_1446 SG48_RS07400 1485260 1486060 + hypothetical protein gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07400 SG48_RS07405 SG48_1447 SG48_RS07405 1486257 1487696 + lactaldehyde dehydrogenase NAD-linked gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07405 SG48_RS07410 SG48_RS07410 SG48_RS07410 1487738 1487989 - glyceraldehyde-3-phosphate dehydrogenase gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07410 SG48_RS07415 SG48_RS07415 SG48_RS07415 1487986 1488363 - glyceraldehyde-3-phosphate dehydrogenase gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07415 SG48_RS07420 SG48_RS07420 SG48_RS07420 1488622 1488738 - glyceraldehyde-3-phosphate dehydrogenase gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07420 SG48_RS07425 SG48_1449 SG48_RS07425 1488927 1489457 + cytochrome B561 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07425 SG48_RS07430 SG48_1451 SG48_RS07430 1489702 1489875 + periplasmic protein gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07430 SG48_RS07435 SG48_1452 SG48_RS07435 1489947 1490096 - protein HokB gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07435 SG48_RS07440 SG48_1455 SG48_RS07440 1490495 1492135 + methyl-accepting chemotaxis protein III gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07440 SG48_RS07445 SG48_1456 SG48_RS07445 1492173 1493096 - transcriptional regulator gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07445 SG48_RS07450 SG48_1457 SG48_RS07450 1493313 1494656 + metalloenzyme gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07450 SG48_RS07455 SG48_1458 mdoD mdoD 1494917 1496536 + glucan biosynthesis protein D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07455 SG48_RS07460 SG48_RS07460 SG48_RS07460 1496457 1496660 - hypothetical protein gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07460 SG48_RS07465 SG48_1459 SG48_RS07465 1496676 1496900 + hypothetical protein gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07465 SG48_RS07470 SG48_1460 SG48_RS07470 1496963 1497502 + ribosomal-protein-serine acetyltransferase gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07470 SG48_RS07475 SG48_1461 SG48_RS07475 1497494 1498474 - hypothetical protein gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07475 SG48_RS07480 SG48_1462 SG48_RS07480 1498586 1499590 + tellurite resistance protein TehA gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07480 SG48_RS07485 SG48_1463 SG48_RS07485 1499587 1500180 + tellurite methyltransferase with TehA confers resistance to tellurite gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07485 SG48_RS07490 SG48_1464 SG48_RS07490 1500482 1501150 + lipoprotein gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07490 SG48_RS07495 SG48_RS07495 SG48_RS07495 1501183 1501386 + TetR family transcriptional regulator gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07495 SG48_RS07500 SG48_RS07500 SG48_RS07500 1501387 1501674 - transposase gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07500 SG48_RS07505 SG48_1466 SG48_RS07505 1501742 1502890 + transposase gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07505 SG48_RS07510 SG48_1467 SG48_RS07510 1502930 1504105 - hypothetical protein gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07510 SG48_RS07515 SG48_1468 SG48_RS07515 1504197 1504733 + transcriptional regulator gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07515 SG48_RS07520 SG48_1469 SG48_RS07520 1504806 1506767 + peptidase gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07520 SG48_RS07525 SG48_RS07525 SG48_RS07525 1506859 1507029 - hypothetical protein gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07525 SG48_RS07530 SG48_1471 SG48_RS07530 1507311 1507487 + mRNA interferase HicA gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07530 SG48_RS07535 SG48_1472 SG48_RS07535 1507512 1507949 + antitoxin gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07535 SG48_RS07540 SG48_1473 SG48_RS07540 1508028 1509434 + transcriptional regulator gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07540 SG48_RS07545 SG48_1474 SG48_RS07545 1509679 1510824 + ABC transporter substrate-binding protein gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07545 SG48_RS07550 SG48_1475 SG48_RS07550 1510842 1511855 + ABC transporter ATPase gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07550 SG48_RS07555 SG48_1476 SG48_RS07555 1511856 1512797 + ABC transporter permease gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07555 SG48_RS07560 SG48_1477 SG48_RS07560 1512787 1513581 + ABC transporter permease gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07560 SG48_RS07565 SG48_1478 SG48_RS07565 1513603 1515027 + gamma-aminobutyraldehyde dehydrogenase catalyzes the formation of 4-aminobutanoate from 4-aminobutanal%3B involved in putrescine degradation gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07565 SG48_RS07570 SG48_RS07570 SG48_RS07570 1515058 1515255 + hypothetical protein gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07570 SG48_RS07575 SG48_1480 SG48_RS07575 1515414 1515587 + DUF2566 domain-containing protein gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07575 SG48_RS07580 SG48_1481 SG48_RS07580 1515673 1515906 + hypothetical protein gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07580 SG48_RS07585 SG48_1482 SG48_RS07585 1515907 1516356 - hypothetical protein gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07585 SG48_RS07590 SG48_1483 SG48_RS07590 1516353 1516871 - L-amino acid N-acyltransferase MnaT gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07590 SG48_RS07595 SG48_1484 SG48_RS07595 1517052 1518089 + NADPH-dependent curcumin reductase gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07595 SG48_RS07600 SG48_1485 SG48_RS07600 1518287 1518952 + transcriptional regulator gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07600 SG48_RS07605 SG48_1486 SG48_RS07605 1518988 1521090 - TonB-dependent receptor gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07605 SG48_RS07610 SG48_1487 SG48_RS07610 1521332 1522393 + ATP-binding protein%2C periplasmic%2C function unknown gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07610 SG48_RS07615 SG48_1488 SG48_RS07615 1522506 1524005 - L-asparagine permease involved in the transporte of L-asparagine gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07615 SG48_RS07620 SG48_1489 SG48_RS07620 1524272 1524889 + glutathione S-transferase gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07620 SG48_RS07625 SG48_1490 SG48_RS07625 1524965 1525177 + IPR020099 family protein gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07625 SG48_RS07630 SG48_RS07630 SG48_RS07630 1526164 1527963 + type IV secretion protein Rhs gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07630 SG48_RS07635 SG48_1492 SG48_RS07635 1527947 1528429 + immunity protein for RhsE gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07635 SG48_RS07640 SG48_RS07640 SG48_RS07640 1528611 1529357 + hypothetical protein gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07640 SG48_RS07645 SG48_1494 SG48_RS07645 1529841 1530977 + hypothetical protein gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07645 SG48_RS07650 SG48_1495 SG48_RS07650 1531077 1531310 + tautomerase PptA 4-OT%3B member of subfamily 5%3B forms a dimer%3B the function in the Escherichia coli cell is unknown gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07650 SG48_RS07655 SG48_1496 SG48_RS07655 1531307 1531876 - flavin reductase like-protein gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07655 SG48_RS07660 SG48_1497 SG48_RS07660 1532049 1532894 + N-hydroxyarylamine O-acetyltransferase catalyzes the addition of the acetyl moity of acetyl-CoA to an N-hydroxy-arylamine to form an N-acetoxyarylamine gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07660 SG48_RS07665 SG48_1498 SG48_RS07665 1532990 1533883 - PhzC-PhzF family protein gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07665 SG48_RS07670 SG48_1499 narI narI 1533962 1534642 - respiratory nitrate reductase subunit gamma with NarGJH catalyzes the reduction of nitrate%3B the gamma subunit localizes NarGHI to the membrane%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07670 SG48_RS07675 SG48_1500 SG48_RS07675 1534639 1535334 - nitrate reductase molybdenum cofactor assembly chaperone NarW delta subunit of nitrate reductase 1%3B chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1 gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07675 SG48_RS07680 SG48_1501 narH narH 1535334 1536878 - nitrate reductase subunit beta with NarGJI catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07680 SG48_RS07685 SG48_1502 narZ narZ 1536875 1540615 - respiratory nitrate reductase 2 alpha chain with NarYV catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli%3B expression of nitrate reductase Z is not dependent on nitrate levels gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07685 SG48_RS07690 SG48_1503 SG48_RS07690 1540697 1542085 - nitrate/nitrite transporter NarU involved in the transport of nitrate and nitrite gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07690 SG48_RS07695 SG48_RS07695 SG48_RS07695 1542409 1543739 - hypothetical protein gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07695 SG48_RS07700 SG48_RS07700 SG48_RS07700 1543763 1544053 - lipoprotein gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07700 SG48_RS07705 SG48_1506 SG48_RS07705 1544313 1545137 - aromatic amino acid exporter gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07705 SG48_RS07710 SG48_RS07710 SG48_RS07710 1545426 1546013 + sulfate ABC transporter substrate-binding protein gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07710 SG48_RS07715 SG48_RS07715 SG48_RS07715 1546062 1548473 + formate dehydrogenase subunit alpha gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07715 SG48_RS07720 SG48_1508 SG48_RS07720 1548486 1549370 + formate dehydrogenase nitrate-inducible iron-sulfur subunit beta subunit%3B involved in the use of formate as an electron donor during aerobic respiration%3B acts to transfer electrons from the major(alpha subunit) to the cytochrome b556(gamma subunit) gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07720 SG48_RS07725 SG48_1509 SG48_RS07725 1549363 1550016 + formate dehydrogenase nitrate-inducible cytochrome b556(Fdn) subunit cytochrome b556(FDO) component%3B heme containing gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07725 SG48_RS07730 SG48_1510 SG48_RS07730 1550423 1550707 - transcriptional regulator gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07730 SG48_RS07735 SG48_1511 adhP adhP 1550853 1551863 - alcohol dehydrogenase similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07735 SG48_RS07740 SG48_1512 SG48_RS07740 1551997 1553694 - NAD-dependent malic enzyme gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07740 SG48_RS07745 SG48_1513 rpsV rpsV 1553851 1553988 - stationary-phase-induced ribosome-associated protein protein D%3B stationary-phase-induced ribosome-associated%3B in Escherichia coli this protein becomes associated with the ribosome%3B expression increases during stationary phase gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07745 SG48_RS07750 SG48_1514 SG48_RS07750 1554090 1554305 - protein bdm gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07750 SG48_RS07755 SG48_1515 SG48_RS07755 1554650 1555081 + peroxiredoxin OsmC gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07755 SG48_RS07760 SG48_1516 SG48_RS07760 1555137 1556063 - peptide ABC transporter ATP-binding protein gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07760 SG48_RS07765 SG48_1517 SG48_RS07765 1556056 1557042 - peptide ABC transporter ATP-binding protein gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07765 SG48_RS07770 SG48_1518 SG48_RS07770 1557039 1557935 - peptide ABC transporter permease gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07770 SG48_RS07775 SG48_1519 SG48_RS07775 1557932 1558954 - peptide ABC transporter permease gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07775 SG48_RS07780 SG48_1520 SG48_RS07780 1558956 1560506 - peptide ABC transporter substrate-binding protein gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07780 SG48_RS07785 SG48_1521 SG48_RS07785 1560520 1561101 - D-alanyl-D-alanine dipeptidase catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent%3B involved in peptidoglycan synthesis gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07785 SG48_RS07790 SG48_1522 SG48_RS07790 1561359 1563782 - diguanylate phosphodiesterase heme-regulated phosphodiesterase with phosphodiesterase activity with cGMP%3B cold- and stationary phase-induced bioflim regulator%3B oxygen sensor gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07790 SG48_RS07795 SG48_1523 SG48_RS07795 1563783 1565165 - diguanylate cyclase gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07795 SG48_RS07800 SG48_1524 SG48_RS07800 1565529 1566683 - hypothetical protein gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07800 SG48_RS07805 SG48_1525 SG48_RS07805 1566979 1568514 - glutamate/gamma-aminobutyrate antiporter gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07805 SG48_RS07810 SG48_1526 SG48_RS07810 1568670 1570070 - glutamate decarboxylase beta gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07810 SG48_RS07815 SG48_RS07815 SG48_RS07815 1570081 1570179 - hypothetical protein gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07815 SG48_RS07820 SG48_1527 SG48_RS07820 1570432 1573215 - zinc protease gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07820 SG48_RS07825 SG48_1528 SG48_RS07825 1573272 1575644 - TonB-dependent receptor gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07825 SG48_RS07830 SG48_1529 SG48_RS07830 1575682 1577367 - ABC transporter ATP-binding protein gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07830 SG48_RS07835 SG48_1530 SG48_RS07835 1577658 1578815 - anaerobic sulfatase maturase gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07835 SG48_RS07840 SG48_1531 SG48_RS07840 1578867 1580549 - Ser-type periplasmic non-aryl sulfatase gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07840 SG48_RS07845 SG48_1532 SG48_RS07845 1580951 1581712 - transcriptional regulator regulates the cellular response to acid resistance gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07845 SG48_RS07850 SG48_1533 SG48_RS07850 1581787 1581984 - two-component-system connector protein SafA gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07850 SG48_RS07855 SG48_1534 SG48_RS07855 1582232 1584511 - hypothetical protein in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell%3B involved with increased resistance to low pH%3B member of the prokaryotic molybdopterin-containing oxidoreductase family gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07855 SG48_RS07860 SG48_1535 SG48_RS07860 1584845 1585759 - fimbrial-like adhesin protein gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07860 SG48_RS07865 SG48_1536 SG48_RS07865 1585818 1586321 - fimbrial-like adhesin protein gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07865 SG48_RS07870 SG48_1537 SG48_RS07870 1586334 1586864 - fimbrial-like adhesin protein gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07870 SG48_RS07875 SG48_RS07875 SG48_RS07875 1586878 1588026 - fimbrial protein FimD gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07875 SG48_RS07880 SG48_RS07880 SG48_RS07880 1588382 1588561 - transcriptional regulator gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07880 SG48_RS07885 SG48_1540 SG48_RS07885 1588879 1590201 - serine/threonine protein kinase gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07885 SG48_RS07890 SG48_1541 SG48_RS07890 1590201 1590467 - antitoxin HipB gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07890 SG48_RS07895 SG48_RS07895 SG48_RS07895 1590690 1592090 - hypothetical protein gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07895 SG48_RS07900 SG48_RS07900 SG48_RS07900 1592134 1596111 - hypothetical protein gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07900 SG48_RS07905 SG48_1543 SG48_RS07905 1596642 1598234 - autoinducer 2 kinase LsrK gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07905 SG48_RS07910 SG48_1544 SG48_RS07910 1598313 1599266 - LsrR family transcriptional regulator regulates the transcription of lsr genes%3B involved in autoinducer 2 uptake%2C biofilm formation and stress responses gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07910 SG48_RS07915 SG48_1545 SG48_RS07915 1599515 1601050 + autoinducer 2 import ATP-binding protein LsrA gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07915 SG48_RS07920 SG48_1546 SG48_RS07920 1601044 1602072 + autoinducer 2 import system permease LsrC with LsrADB is involved in the transport of autoindiuce 2 gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07920 SG48_RS07925 SG48_1547 SG48_RS07925 1602072 1603064 + autoinducer 2 import system permease LsrD gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07925 SG48_RS07930 SG48_1548 SG48_RS07930 1603076 1604098 + autoinducer 2-binding protein LsrB with lsrACD is involved in the transport of autoinducer 2 into the cell gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07930 SG48_RS07935 SG48_1549 SG48_RS07935 1604125 1605000 + autoinducer-2 (AI-2) aldolase involved in autoinducer 2 transport and processing gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07935 SG48_RS07940 SG48_1550 SG48_RS07940 1605024 1605314 + autoinducer 2-degrading protein LsrG gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07940 SG48_RS07945 SG48_1551 SG48_RS07945 1605371 1606129 + trans-aconitate 2-methyltransferase catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07945 SG48_RS07950 SG48_1552 SG48_RS07950 1606133 1607047 - bestrophin family inner membrane protein gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07950 SG48_RS07955 SG48_RS07955 SG48_RS07955 1606997 1607197 + hypothetical protein gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07955 SG48_RS07960 SG48_1553 SG48_RS07960 1607254 1608705 - altronate oxidoreductase catalyzes the formation of D-tagaturonate from D-altronate gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07960 SG48_RS07965 SG48_1554 SG48_RS07965 1608932 1609879 - diguanylate cyclase gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07965 SG48_RS07970 SG48_1555 SG48_RS07970 1609991 1610350 - DUF4186 domain-containing protein gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07970 SG48_RS07975 SG48_1556 SG48_RS07975 1610350 1611276 - glutaminase 2 catalyzes the formation of glutamate from glutamine gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07975 SG48_RS07980 SG48_1557 SG48_RS07980 1611340 1612728 - succinate semialdehyde dehydrogenase [NAD(P)+] Sad gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07980 SG48_RS07985 SG48_1558 SG48_RS07985 1612829 1613710 + transcriptional regulator gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07985 SG48_RS07990 SG48_1559 SG48_RS07990 1613788 1614903 + hypothetical protein gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07990 SG48_RS07995 SG48_1560 SG48_RS07995 1615053 1616243 + sugar efflux transporter gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS07995 SG48_RS08000 SG48_1561 SG48_RS08000 1616268 1616933 - membrane protein gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08000 SG48_RS08005 SG48_1562 SG48_RS08005 1617145 1617579 + MarR family transcriptional regulator Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08005 SG48_RS08010 SG48_1563 SG48_RS08010 1617593 1617982 + MDR efflux pump AcrAB transcriptional activator MarA transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype%3B also activates sodA%2C zwf and micF gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08010 SG48_RS08015 SG48_1564 SG48_RS08015 1618014 1618232 + multiple antibiotic resistance protein MarB gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08015 SG48_RS08020 SG48_1565 SG48_RS08020 1618263 1619162 - amino acid metabolite efflux pump gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08020 SG48_RS08025 SG48_1566 SG48_RS08025 1619357 1620544 + transporter YdeF%3B uncharacterized member of the major facilitator superfamily (MFS) of transporters gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08025 SG48_RS08030 SG48_1567 SG48_RS08030 1620671 1620766 + hypothetical protein gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08030 SG48_RS08035 SG48_1569 SG48_RS08035 1620985 1621875 - diguanylate cyclase required for pgaD induction gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08035 SG48_RS08040 SG48_1570 SG48_RS08040 1622130 1622522 - hydrogen peroxide resistance protein gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08040 SG48_RS08045 SG48_1571 SG48_RS08045 1622798 1623316 + hypothetical protein gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08045 SG48_RS08050 SG48_1572 SG48_RS08050 1623360 1625405 - peptidyl-dipeptidase dcp gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08050 SG48_RS08055 SG48_1573 SG48_RS08055 1625542 1626288 + NADP-dependent 3-hydroxy acid dehydrogenase YdfG NADP(+)-dependent%3B catalyzes the formation of 3-hydroxypropionate from the toxic malonic semialdehyde%2C catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine%3B can also use 3-hydroxybutyrate%2C 3-hydroxy-isobutyrate%2C D-threonine%2C L-allo-threonine%2CD-serine gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08055 SG48_RS08060 SG48_1574 SG48_RS08060 1626377 1627063 + transcriptional regulator gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08060 SG48_RS08065 SG48_1575 SG48_RS08065 1627240 1627443 + hypothetical protein gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08065 SG48_RS08070 SG48_1576 SG48_RS08070 1627478 1628938 - NAD-dependent D-mannonate oxidoreductase gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08070 SG48_RS08075 SG48_RS08075 SG48_RS08075 1629027 1630310 - transporter gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08075 SG48_RS08080 SG48_1578 SG48_RS08080 1631097 1631330 + cold-shock protein gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08080 SG48_RS08085 SG48_1579 SG48_RS08085 1631647 1632237 + Qin prophage%3B site-specific recombinase gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08085 SG48_RS08090 SG48_1580 SG48_RS08090 1632335 1632910 - Tail fiber assembly protein homolog from lambdoid prophage Qin gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08090 SG48_RS08095 SG48_1581 SG48_RS08095 1632910 1633872 - Side tail fiber protein homolog from lambdoid prophage Qin gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08095 SG48_RS08100 SG48_RS08100 SG48_RS08100 1633823 1634392 - protein convertase gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08100 SG48_RS08105 SG48_1583 SG48_RS08105 1634781 1635014 + hypothetical protein gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08105 SG48_RS08110 SG48_1584 SG48_RS08110 1635072 1635482 + Qin prophage%3B uncharacterized protein gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08110 SG48_RS08115 SG48_1585 SG48_RS08115 1635634 1635807 - protein GnsB gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08115 SG48_RS08120 SG48_1586 SG48_RS08120 1635979 1636155 - hypothetical protein gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08120 SG48_RS08125 SG48_1587 SG48_RS08125 1636480 1636692 - cold-shock protein CspI gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08125 SG48_RS08130 SG48_1588 SG48_RS08130 1637055 1637552 - Rz-like protein%2C Qin prophage gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08130 SG48_RS08135 SG48_1590 SG48_RS08135 1637549 1638082 - lysozyme from lambdoid prophage Qin gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08135 SG48_RS08140 SG48_1591 SG48_RS08140 1638079 1638390 - Qin prophage%3B uncharacterized protein gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08140 SG48_RS08145 SG48_1592 SG48_RS08145 1638395 1638610 - Lysis protein S homolog from lambdoid prophage Qin gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08145 SG48_RS08150 SG48_1593 SG48_RS08150 1639364 1639579 - cold-shock protein CspB gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08150 SG48_RS08155 SG48_1594 SG48_RS08155 1639880 1640092 + cold-shock protein CspF gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08155 SG48_RS08160 SG48_1595 SG48_RS08160 1640514 1641266 - Antitermination protein Q homolog from lambdoid prophage Qin gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08160 SG48_RS08165 SG48_1596 SG48_RS08165 1641280 1642329 - Qin prophage%3B uncharacterized protein gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08165 SG48_RS08170 SG48_RS08170 SG48_RS08170 1642331 1642609 - hypothetical protein gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08170 SG48_RS08175 SG48_1597 SG48_RS08175 1642676 1642927 - Qin prophage%3B uncharacterized protein gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08175 SG48_RS08180 SG48_1598 SG48_RS08180 1643144 1643299 - protein HokD gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08180 SG48_RS08185 SG48_1599 SG48_RS08185 1643371 1643658 - mRNA interferase RelE gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08185 SG48_RS08190 SG48_1600 SG48_RS08190 1643658 1643897 - antitoxin RelB Qin prophage%3B bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08190 SG48_RS08195 SG48_1602 SG48_RS08195 1644430 1644762 + protein FlxA gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08195 SG48_RS08200 SG48_RS08200 SG48_RS08200 1645364 1645661 - hypothetical protein gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08200 SG48_RS08205 SG48_1605 SG48_RS08205 1645645 1645875 - repressor protein of division inhibition gene dicB gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08205 SG48_RS08210 SG48_1606 SG48_RS08210 1645959 1646366 + transcriptional regulator The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC%2C but its specific role in cellular replication and mode of action are still unknown. gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08210 SG48_RS08215 SG48_1607 SG48_RS08215 1646533 1646688 + Qin prophage%3B uncharacterized protein gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08215 SG48_RS08220 SG48_1609 SG48_RS08220 1646848 1647066 + hypothetical protein gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08220 SG48_RS08225 SG48_RS08225 SG48_RS08225 1647070 1647363 - hypothetical protein gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08225 SG48_RS08230 SG48_1611 SG48_RS08230 1647634 1647822 + division inhibition protein DicB gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08230 SG48_RS08235 SG48_1612 SG48_RS08235 1647819 1648010 + Qin prophage%3B uncharacterized protein gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08235 SG48_RS08240 SG48_RS08240 SG48_RS08240 1648322 1648633 - cell surface protein gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08240 SG48_RS08245 SG48_RS08245 SG48_RS08245 1648837 1649562 + transposase gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08245 SG48_RS08250 SG48_RS08250 SG48_RS08250 1649537 1650733 + hypothetical protein gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08250 SG48_RS08255 SG48_1616 SG48_RS08255 1650921 1651940 - starvation-sensing protein RspB gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08255 SG48_RS08260 SG48_1617 SG48_RS08260 1651952 1653166 - starvation-sensing protein RspA starvation-sensing protein%3B maybe involved in homoserine lactone degradation gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08260 SG48_RS08265 SG48_1618 SG48_RS08265 1653372 1653698 - membrane protein gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08265 SG48_RS08270 SG48_1619 SG48_RS08270 1653833 1654174 + hypothetical protein gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08270 SG48_RS08275 SG48_1620 SG48_RS08275 1654209 1654769 + spermidine N(1)-acetyltransferase catalyzes the formation of N(1)- and N(8)-acetylspermidine from spermidine gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08275 SG48_RS08280 SG48_1621 SG48_RS08280 1654772 1655518 - lipoprotein gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08280 SG48_RS08285 SG48_1622 SG48_RS08285 1655590 1655895 + DUF1161 domain-containing protein gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08285 SG48_RS08290 SG48_1623 SG48_RS08290 1656094 1658520 + selenate reductase periplasmic gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08290 SG48_RS08295 SG48_1624 SG48_RS08295 1658608 1661004 + dimethyl sulfoxide reductase subunit A gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08295 SG48_RS08300 SG48_1625 SG48_RS08300 1661015 1661632 + dimethyl sulfoxide reductase oxidoreductase%2C Fe-S subunit%3B terminal electron transfer protein for the reduction of DMSO gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08300 SG48_RS08305 SG48_1626 SG48_RS08305 1661634 1662488 + dimethyl sulfoxide reductase gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08305 SG48_RS08310 SG48_1627 SG48_RS08310 1662531 1663145 + Tat proofreading chaperone DmsD binds to the twin-arginine signal peptides of certain proteins%2C including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08310 SG48_RS08315 SG48_1628 SG48_RS08315 1663340 1664596 + voltage-gated ClC-type chloride channel ClcB gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08315 SG48_RS08320 SG48_1629 SG48_RS08320 1664549 1665244 - ATP-dependent dethiobiotin synthetase BioD 2 DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08320 SG48_RS08325 SG48_1630 SG48_RS08325 1665369 1666589 - protein mlc mlc%2C controls the expression of genes involved in the phosphotransferase and phosphoenolpyruvate systems%2C regulates genes involved in the uptake of sugars gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08325 SG48_RS08330 SG48_1631 SG48_RS08330 1666724 1667617 - LysR family transcriptional regulator gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08330 SG48_RS08335 SG48_1632 SG48_RS08335 1667724 1668977 + transporter gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08335 SG48_RS08340 SG48_1633 SG48_RS08340 1669374 1669709 + acid-shock protein required for growth and survival under moderately acid conditions gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08340 SG48_RS08345 SG48_1634 SG48_RS08345 1669802 1669885 + stationary phase-induced protein gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08345 SG48_RS08350 SG48_1635 SG48_RS08350 1669985 1670806 + peptidase gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08350 SG48_RS08355 SG48_1636 SG48_RS08355 1670845 1671174 - spermidine export protein MdtI with MdtJ is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08355 SG48_RS08360 SG48_1637 SG48_RS08360 1671161 1671526 - spermidine export protein MdtJ with MdtI is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08360 SG48_RS08365 SG48_1638 tqsA tqsA 1671938 1672972 + AI-2 transporter TqsA transport of quorum-sensing signal%3B mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08365 SG48_RS08370 SG48_1639 pntB pntB 1672997 1674385 - NAD(P) transhydrogenase subunit beta catalyzes reversible transfer of hydride ion equivalent between NAD and NADP%3B membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane%3B forms a tetramer composed of two alpha and 2 beta subunits%3B AB-stereospecific enzyme gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08370 SG48_RS08375 SG48_1640 pntA pntA 1674396 1675928 - NAD(P) transhydrogenase subunit alpha forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane%3B involved in catalyzing transfer of hydride ion equivalents between NAD and NADP%3B stereospecific (AB-specific)%3B functions as a proton pump by translocating protons from cytoplasm to periplasm gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08375 SG48_RS08380 SG48_1641 SG48_RS08380 1676452 1677396 + hypothetical protein gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08380 SG48_RS08385 SG48_1642 SG48_RS08385 1677582 1678964 + arginine/ornithine antiporter transporter gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08385 SG48_RS08390 SG48_1643 SG48_RS08390 1679001 1679723 + dihydrofolate reductase FolM gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08390 SG48_RS08395 SG48_1644 SG48_RS08395 1679720 1680055 - hypothetical protein gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08395 SG48_RS08400 SG48_1645 SG48_RS08400 1680184 1680903 + two-component system response regulator response regulator in two-component regulatory system with RstB gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08400 SG48_RS08405 SG48_1646 SG48_RS08405 1680907 1682208 + two-component system sensor histidine kinase gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08405 SG48_RS08410 SG48_1647 SG48_RS08410 1682284 1683213 + DNA replication terminus site-binding protein binds to DNA replication terminator sequences to prevent passage of replication forks gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08410 SG48_RS08415 SG48_1648 fumC fumC 1683210 1684613 - fumarate hydratase class II class II family (does not require metal)%3B tetrameric enzyme%3B fumarase C%3B reversibly converts (S)-malate to fumarate and water%3B functions in the TCA cycle gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08415 SG48_RS08420 SG48_1649 SG48_RS08420 1684756 1686402 - fumarate hydratase class I%2C aerobic catalyzes the formation of malate from fumerate gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08420 SG48_RS08425 SG48_1650 SG48_RS08425 1686601 1687776 + mannose-6-phosphate isomerase catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08425 SG48_RS08430 SG48_1651 SG48_RS08430 1687877 1689385 + hypothetical protein gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08430 SG48_RS08435 SG48_1652 SG48_RS08435 1689611 1690876 - porin gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08435 SG48_RS08440 SG48_1653 SG48_RS08440 1690915 1692288 - glucuronide carrier protein gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08440 SG48_RS08445 SG48_1654 SG48_RS08445 1692285 1694096 - beta-glucuronidase gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08445 SG48_RS08450 SG48_1655 SG48_RS08450 1694487 1695077 - transcriptional regulator gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08450 SG48_RS08455 SG48_1656 SG48_RS08455 1695298 1696065 - 7-alpha-hydroxysteroid dehydrogenase Acts on the hydroxyl group at position 7 of the steroid frame gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08455 SG48_RS08460 SG48_1657 SG48_RS08460 1696177 1697205 - maltose regulon regulatory protein MalI regulates malXY which are involved in maltose-glucose transport gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08460 SG48_RS08465 SG48_1658 SG48_RS08465 1697380 1698972 + PTS maltose- and glucose EIICB component phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%3B catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane%3B component IIB catalyzes the phosphorylation of the sugar molecule%3B IIC forms the translocation channel and contains the substrate specific binding site gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08465 SG48_RS08470 SG48_1659 SG48_RS08470 1698982 1700154 + protein MalY catalyzes the formation of homocysteine and pyruvate from cystathionine%3B also acts a a negative regulator for the mal regulon but interacting with the transcriptional activator MalT gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08470 SG48_RS08475 SG48_1660 SG48_RS08475 1700258 1701259 + adenosine deaminase gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08475 SG48_RS08480 SG48_1661 SG48_RS08480 1701293 1702333 - oxidoreductase gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08480 SG48_RS08485 SG48_1662 SG48_RS08485 1702576 1702701 + divisome-associated membrane protein Blr gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08485 SG48_RS08490 SG48_1663 SG48_RS08490 1702974 1703189 + nucleoid-associated protein YdgT%3B in E. coli%2C when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC%3B seems to play a role in optimizing the activity of oriC%3B non-essential%3B Hha protein paralog%3B in an hha mutant background%2C cnu is overexpressed and can compensate hha-induced phenotypes gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08490 SG48_RS08495 SG48_1664 SG48_RS08495 1703275 1703715 + hypothetical protein gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08495 SG48_RS08500 SG48_1665 SG48_RS08500 1703792 1704373 + electron transport complex subunit RsxA gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08500 SG48_RS08505 SG48_1666 SG48_RS08505 1704373 1704951 + electron transport complex subunit RsxB part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08505 SG48_RS08510 SG48_1667 SG48_RS08510 1704944 1707166 + electron transporter RsxC part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08510 SG48_RS08515 SG48_1668 rnfD rnfD 1707167 1708225 + electron transport complex subunit RsxD RnfD%3B RsxD%3B required for nitrogen fixation in Rhodobacter capsulatus%3B part of a membrane-bound complex thought to be involved in electron transport to nitrogenase%3B in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08515 SG48_RS08520 SG48_1669 SG48_RS08520 1708229 1708849 + electron transport complex subunit RsxG part of membrane-bound complex hought to be involved in electron transport to nitrogen gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08520 SG48_RS08525 SG48_1670 SG48_RS08525 1708853 1709548 + electron transporter RsxE gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08525 SG48_RS08530 SG48_1671 SG48_RS08530 1709548 1710183 + endonuclease III DNA-(apurinic or apyrimidinic site) lyase%3B has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity%3B removed damaged DNA at cytosines%2C thymines and guanines gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08530 SG48_RS08535 SG48_RS08535 SG48_RS08535 1710311 1710511 + hypothetical protein gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08535 SG48_RS08540 SG48_1672 tppB tppB 1710794 1712296 + dipeptide and tripeptide permease A mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium%3B member of proton-dependent oligopeptide transport (POT) system family%3B in Escherichia coli this gene is regulated by OmpR although not via osmoregulation gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08540 SG48_RS08545 SG48_1673 SG48_RS08545 1712402 1713007 + glutathione S-transferase gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08545 SG48_RS08550 SG48_1674 SG48_RS08550 1713051 1713911 - pyridoxamine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08550 SG48_RS08555 SG48_1675 SG48_RS08555 1713973 1715247 - tyrosine--tRNA ligase gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08555 SG48_RS08560 SG48_1676 SG48_RS08560 1715376 1716032 - pyridoxine/pyridoxamine 5'-phosphate oxidase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08560 SG48_RS08565 SG48_1677 SG48_RS08565 1716091 1716420 - lysozyme inhibitor MliC%3B membrane-bound lysozyme inhibitor of c-type lysozyme gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08565 SG48_RS08570 SG48_1678 anmK anmK 1716518 1717627 - anhydro-N-acetylmuramic acid kinase catalyzes hydrolysis of 1%2C6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate%3B involved in murein recycling gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08570 SG48_RS08575 SG48_1679 SG48_RS08575 1717901 1718368 + hypothetical protein gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08575 SG48_RS08580 SG48_1680 SG48_RS08580 1718415 1718849 - SlyA family transcriptional regulator Transcription regulator that can both activate or repress expression gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08580 SG48_RS08585 SG48_1681 SG48_RS08585 1719050 1719286 + membrane protein gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08585 SG48_RS08590 SG48_1682 SG48_RS08590 1719289 1720146 + membrane fusion protein (MFP) of YdhJK efflux pump gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08590 SG48_RS08595 SG48_1683 SG48_RS08595 1720146 1722158 + efflux protein (PET) component of YdhJK efflux pump gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08595 SG48_RS08600 SG48_1684 SG48_RS08600 1722159 1722680 - superoxide dismutase [Cu-Zn] SodC%3B copper and zinc binding%3B converts superoxide radicals to hydrogen peroxide and water gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08600 SG48_RS08605 SG48_1685 SG48_RS08605 1722761 1723657 - oxidoreductase gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08605 SG48_RS08610 SG48_1686 SG48_RS08610 1723706 1723945 - DUF1289 domain-containing protein gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08610 SG48_RS08615 SG48_1687 SG48_RS08615 1724048 1724647 + transcriptional regulator represses nemA which is involved in degradation of N-ethylmaleimide gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08615 SG48_RS08620 SG48_1688 SG48_RS08620 1724684 1725781 + N-ethylmaleimide reductase FMN-linked%3B catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08620 SG48_RS08625 SG48_1689 SG48_RS08625 1725862 1726269 + lactoylglutathione lyase Ni-dependent%3B catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08625 SG48_RS08630 SG48_1690 SG48_RS08630 1726372 1727019 + ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08630 SG48_RS08635 SG48_1691 SG48_RS08635 1727112 1731728 + ATP-dependent helicase similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases%3B longest known protein in E. coli gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08635 SG48_RS08640 SG48_1692 SG48_RS08640 1731779 1732126 - glutaredoxin gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08640 SG48_RS08645 SG48_1693 SG48_RS08645 1732460 1733275 + murein DD-endopeptidase MepH gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08645 SG48_RS08650 SG48_1694 SG48_RS08650 1733403 1733984 + superoxide dismutase [Fe] SodB%3B iron binding%3B present under aerobic and anaerobic conditions%3B destroys free radicals gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08650 SG48_RS08655 SG48_1695 SG48_RS08655 1734146 1735315 - transporter gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08655 SG48_RS08660 SG48_1696 SG48_RS08660 1735481 1735570 - stress response membrane gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08660 SG48_RS08665 SG48_1697 SG48_RS08665 1735869 1736894 + PurR family transcriptional regulator binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08665 SG48_RS08670 SG48_1698 SG48_RS08670 1736891 1737823 - LysR family transcriptional regulator gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08670 SG48_RS08675 SG48_1699 SG48_RS08675 1737936 1739147 + Bcr/CflA family drug resistance efflux transporter uncharacterized member of the major facilitator superfamily (MFS) gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08675 SG48_RS08680 SG48_1700 SG48_RS08680 1739438 1740586 + cyclopropane-fatty-acyl-phospholipid synthase catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08680 SG48_RS08685 SG48_1701 SG48_RS08685 1740626 1741267 - riboflavin synthase catalyzes the formation of riboflavin from 6%2C7-dimethyl-8-(1-D-ribityl)lumazine gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08685 SG48_RS08690 SG48_1702 SG48_RS08690 1741482 1742855 + multidrug resistance protein MdtK NorM%3B MdtK%3B functions as a Na(+)/drug antiporter%3B inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08690 SG48_RS08695 SG48_1703 SG48_RS08695 1742896 1744152 - autotransporter adhesin-related protein gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08695 SG48_RS08700 SG48_1704 SG48_RS08700 1744460 1744536 + tRNA-Val tRNA gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08700 SG48_RS08705 SG48_1705 SG48_RS08705 1744541 1744617 + tRNA-Val tRNA gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08705 SG48_RS08710 SG48_1706 SG48_RS08710 1744725 1745030 + monooxygenase gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08710 SG48_RS08715 SG48_1707 SG48_RS08715 1745156 1746760 + oxidoreductase gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08715 SG48_RS08720 SG48_1708 SG48_RS08720 1746772 1747584 - FNR%2C Nar%2C NarP-regulated protein%3B subunit of YdhYVWXUT oxidoreductase complex gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08720 SG48_RS08725 SG48_1709 SG48_RS08725 1747588 1748373 - protein PhsC gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08725 SG48_RS08730 SG48_1710 SG48_RS08730 1748370 1749038 - 4Fe-4S ferredoxin gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08730 SG48_RS08735 SG48_1711 SG48_RS08735 1749102 1749740 - hypothetical protein gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08735 SG48_RS08740 SG48_1712 SG48_RS08740 1749753 1751855 - oxidoreductase subunit gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08740 SG48_RS08745 SG48_1713 SG48_RS08745 1751876 1752502 - 4Fe-4S ferredoxin gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08745 SG48_RS08750 SG48_1714 SG48_RS08750 1752957 1753166 - hypothetical protein gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08750 SG48_RS08755 SG48_1715 SG48_RS08755 1753723 1755135 + pyruvate kinase I catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08755 SG48_RS08760 SG48_1716 SG48_RS08760 1755446 1755682 + murein lipoprotein major outer membrane lipoprotein%3B interacts with peptidoglycan to maintain the integrity of the cell envelope gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08760 SG48_RS08765 SG48_1717 SG48_RS08765 1755746 1756750 - transpeptidase catalyzes the formation of a meso-diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link in peptidoglycan synthesis gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08765 SG48_RS08770 SG48_1718 SG48_RS08770 1756899 1757315 - cysteine desulfuration protein SufE Acts with SufS to catalyze the formation of L-alanine from L-cysteine gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08770 SG48_RS08775 SG48_1719 SG48_RS08775 1757328 1758548 - cysteine desulfurase gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08775 SG48_RS08780 SG48_1720 SG48_RS08780 1758545 1759816 - Fe-S cluster assembly protein SufD with SufBC activates cysteine desulfurase SufS gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08780 SG48_RS08785 SG48_1721 sufC sufC 1759791 1760537 - Fe-S cluster assembly ATPase SufC part of SUF system involved in inserting iron-sulfur clusters into proteins%3B in Escherichia coli this protein forms a complex with SufBD%3B the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08785 SG48_RS08790 SG48_1722 SG48_RS08790 1760547 1762034 - FeS cluster assembly protein SufB with SufCD activates cysteine desulfurase SufS gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08790 SG48_RS08795 SG48_1723 sufA sufA 1762043 1762411 - protein SufA functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]%3B [4Fe-4S]) are assembled%3B forms a homodimer%3B similar to IscA protein gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08795 SG48_RS08800 SG48_1725 SG48_RS08800 1762959 1763147 - hypothetical protein gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08800 SG48_RS08805 SG48_1726 SG48_RS08805 1763247 1763657 - 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase required for efficient enterobactin production gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08805 SG48_RS08810 SG48_1727 SG48_RS08810 1763654 1766710 - FAD-linked oxidoreductase gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08810 SG48_RS08815 SG48_1728 SG48_RS08815 1767099 1768211 + hypothetical protein YdiK%3B inner membrane protein%3B ydiK promoter presents a PurR sequence%2C suggesting that its expression is purine-regulated%3B unknown function gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08815 SG48_RS08820 SG48_1730 SG48_RS08820 1768640 1768996 + HTH domain DNA-binding protein gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08820 SG48_RS08825 SG48_1731 SG48_RS08825 1769096 1770310 + transporter gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08825 SG48_RS08830 SG48_1732 SG48_RS08830 1770537 1771802 + transporter gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08830 SG48_RS08835 SG48_1733 SG48_RS08835 1771814 1772680 + quinate/shikimate dehydrogenase YdiB%3B quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08835 SG48_RS08840 SG48_1734 SG48_RS08840 1772711 1773469 + 3-dehydroquinate dehydratase gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08840 SG48_RS08845 SG48_1735 SG48_RS08845 1773612 1775207 + acetate CoA-transferase YdiF gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08845 SG48_RS08850 SG48_1736 SG48_RS08850 1775221 1776372 + acyl-CoA dehydrogenase may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08850 SG48_RS08855 SG48_1737 SG48_RS08855 1776415 1777326 - transcriptional regulator gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08855 SG48_RS08860 SG48_RS08860 SG48_RS08860 1777429 1777605 - hypothetical protein gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08860 SG48_RS08865 SG48_1738 SG48_RS08865 1777642 1778406 + electron transfer flavoprotein subunit gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08865 SG48_RS08870 SG48_1739 fixB fixB 1778426 1779364 + electron transfer flavoprotein%2C FAD-binding subunit involved in electron transfer during carnitine metabolism gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08870 SG48_RS08875 SG48_1740 SG48_RS08875 1779420 1780709 + electron transfer flavoprotein-quinone oxidoreductase FAD/NAD(P)-binding domain%3B possibly part of an electron transfer system required for anaerobic carnitine reduction gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08875 SG48_RS08880 SG48_1741 SG48_RS08880 1780706 1780999 + ferredoxin-like protein YdiT gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08880 SG48_RS08885 SG48_1742 SG48_RS08885 1781056 1782702 + short-chain-fatty-acid--CoA ligase acts in anaerobic beta-oxidation of fatty acids%3B possible ligase/synthase involved in anaerobic growth on fatty acids gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08885 SG48_RS08890 SG48_1743 SG48_RS08890 1782759 1785137 - phosphoenolpyruvate synthase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08890 SG48_RS08895 SG48_RS08895 SG48_RS08895 1785191 1785358 - hypothetical protein gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08895 SG48_RS08900 SG48_1744 SG48_RS08900 1785470 1786303 + phosphoenolpyruvate synthase regulatory protein gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08900 SG48_RS08905 SG48_1745 SG48_RS08905 1786460 1787506 + phospho-2-dehydro-3-deoxyheptonate aldolase Trp-sensitive gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08905 SG48_RS08910 SG48_1746 SG48_RS08910 1787638 1787829 + hemin uptake protein HemP homolog gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08910 SG48_RS08915 SG48_1747 SG48_RS08915 1787833 1789269 - hypothetical protein gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08915 SG48_RS08920 SG48_1748 SG48_RS08920 1789332 1790045 - anti-FlhD4C2 factor%2C inactive EAL family phosphodiesterase gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08920 SG48_RS08925 SG48_1749 SG48_RS08925 1790292 1790756 - endopeptidase gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08925 SG48_RS08930 SG48_1750 SG48_RS08930 1790834 1791583 - vitamin B12 import ATP-binding protein BtuD ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08930 SG48_RS08935 SG48_1751 btuE btuE 1791583 1792134 - vitamin B12 transport periplasmic protein BtuE similar to glutathione peroxidase%3B member of the btuCED operon which is required for vitamin B12 transport across the inner membrane gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08935 SG48_RS08940 SG48_1752 SG48_RS08940 1792197 1793177 - vitamin B12 import system permease BtuC with BtuD and BtuF transports vitamin B12 into the cell gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08940 SG48_RS08945 SG48_1753 ihfA ihfA 1793278 1793577 - integration host factor subunit alpha This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08945 SG48_RS08950 SG48_1754 pheT pheT 1793582 1795969 - phenylalanine--tRNA ligase subunit beta catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a tetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 2 subfamily gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08950 SG48_RS08955 SG48_1755 SG48_RS08955 1795984 1796967 - phenylalanine--tRNA ligase subunit alpha gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08955 SG48_RS08960 SG48_RS08960 SG48_RS08960 1797081 1797176 - hypothetical protein gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08960 SG48_RS08965 SG48_1757 rplT rplT 1797418 1797774 - 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08965 SG48_RS08970 SG48_1758 SG48_RS08970 1797827 1798024 - 50S ribosomal protein L35 gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08970 SG48_RS08975 SG48_1759 SG48_RS08975 1798121 1798663 - translation initiation factor IF-3 gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08975 SG48_RS08980 SG48_1760 thrS thrS 1798667 1800595 - threonine--tRNA ligase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08980 SG48_RS08985 SG48_RS08985 SG48_RS08985 1801119 1803018 + ankyrin gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08985 SG48_RS08990 SG48_1762 SG48_RS08990 1803190 1803297 + hypothetical protein gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08990 SG48_RS08995 SG48_1763 SG48_RS08995 1803350 1804108 - acid-inducible outer membrane protein gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS08995 SG48_RS09000 SG48_1764 SG48_RS09000 1804395 1805324 + ATP-dependent 6-phosphofructokinase gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09000 SG48_RS09005 SG48_1765 SG48_RS09005 1805425 1805715 + hypothetical protein gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09005 SG48_RS09010 SG48_1766 SG48_RS09010 1805821 1806681 + fructosamine kinase gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09010 SG48_RS09015 SG48_1767 SG48_RS09015 1806722 1807258 - hypothetical protein gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09015 SG48_RS09020 SG48_1768 SG48_RS09020 1807405 1808073 + 2-deoxyglucose-6-phosphate phosphatase YniC%3B catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate%2C mannose 6-phosphate and p-nitrophenyl phosphate gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09020 SG48_RS09025 SG48_1769 SG48_RS09025 1808236 1808826 + hypothetical protein gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09025 SG48_RS09030 SG48_1770 SG48_RS09030 1808959 1810350 + transporter gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09030 SG48_RS09035 SG48_1771 SG48_RS09035 1810354 1811157 - hypothetical protein gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09035 SG48_RS09040 SG48_1772 SG48_RS09040 1811446 1811688 - cell division activator CedA gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09040 SG48_RS09045 SG48_1773 katE katE 1811892 1814153 + catalase HPII Catalase HPII%3B monofunctional catalase that decomposes hydrogen peroxide into water and oxygen%3B serves to protect cells from the toxic effects of hydrogen peroxide gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09045 SG48_RS09050 SG48_1774 SG48_RS09050 1814411 1815160 - chitooligosaccharide deacetylase ChbG gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09050 SG48_RS09055 SG48_1775 SG48_RS09055 1815173 1816525 - 6-phospho-beta-glucosidase catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09055 SG48_RS09060 SG48_1776 SG48_RS09060 1816630 1817469 - transcriptional regulator represses the celABCDF-ydjC operon involved in carbon uptake gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09060 SG48_RS09065 SG48_1777 SG48_RS09065 1817480 1817830 - N%2CN'-diacetylchitobiose-specific phosphotransferase enzyme IIA component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09065 SG48_RS09070 SG48_1778 SG48_RS09070 1817881 1819239 - N%2CN'-diacetylchitobiose permease IIC component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved in N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09070 SG48_RS09075 SG48_1779 SG48_RS09075 1819324 1819644 - N%2CN'-diacetylchitobiose-specific phosphotransferase enzyme IIB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved in N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09075 SG48_RS09080 SG48_1780 SG48_RS09080 1819943 1820281 - osmotically-inducible lipoprotein E osmotically-inducible lipoprotein E%3B activator of ntr-like gene protein gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09080 SG48_RS09085 SG48_1781 nadE nadE 1820483 1821310 + nH(3)-dependent NAD+ synthetase catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP%3B ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one%3B forms homodimers gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09085 SG48_RS09090 SG48_RS09090 SG48_RS09090 1821279 1821470 - hypothetical protein gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09090 SG48_RS09095 SG48_1782 SG48_RS09095 1821540 1822427 + excinuclease cho 3' incision activity%3B acts with UvrC gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09095 SG48_RS09100 SG48_1783 SG48_RS09100 1822387 1822962 - protein Ves gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09100 SG48_RS09105 SG48_1784 SG48_RS09105 1823165 1823650 - spheroplast protein Y periplasmic protein induced by stress response via Cpx and BaeSR system%3B similar to CpxP gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09105 SG48_RS09110 SG48_1785 SG48_RS09110 1823980 1824948 - succinylglutamate desuccinylase catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09110 SG48_RS09115 SG48_1786 SG48_RS09115 1824941 1826284 - N-succinylarginine dihydrolase catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine%2C ammonia and carbon dioxide in arginine degradation gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09115 SG48_RS09120 SG48_1787 astD astD 1826281 1827759 - N-succinylglutamate 5-semialdehyde dehydrogenase a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity%3B converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09120 SG48_RS09125 SG48_1788 SG48_RS09125 1827756 1828790 - arginine N-succinyltransferase gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09125 SG48_RS09130 SG48_1789 SG48_RS09130 1828787 1830007 - succinylornithine aminotransferase catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate%3B also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09130 SG48_RS09135 SG48_1790 SG48_RS09135 1830453 1831259 + exodeoxyribonuclease III gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09135 SG48_RS09140 SG48_1791 SG48_RS09140 1831426 1832136 + TVP38/TMEM64 family membrane protein YdjX gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09140 SG48_RS09145 SG48_1792 SG48_RS09145 1832141 1832818 + ferrodoxin-like lipoprotein gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09145 SG48_RS09150 SG48_1793 SG48_RS09150 1832833 1833540 + hypothetical protein gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09150 SG48_RS09155 SG48_1794 SG48_RS09155 1833540 1834088 + carboxymuconolactone decarboxylase gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09155 SG48_RS09160 SG48_1795 SG48_RS09160 1834098 1835264 + hypothetical protein gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09160 SG48_RS09165 SG48_1796 SG48_RS09165 1835237 1836772 + ABC transporter permease gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09165 SG48_RS09170 SG48_1797 SG48_RS09170 1836772 1837425 + ABC transporter ATPase gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09170 SG48_RS09175 SG48_1798 SG48_RS09175 1837492 1838799 + thiosulfate sulfurtransferase YnjE gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09175 SG48_RS09180 SG48_1799 SG48_RS09180 1838808 1839428 - hypothetical protein gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09180 SG48_RS09185 SG48_1800 SG48_RS09185 1839515 1839922 + CTP pyrophosphohydrolase gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09185 SG48_RS09190 SG48_1801 SG48_RS09190 1839888 1840160 - DUF1496 domain-containing protein gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09190 SG48_RS09195 SG48_1802 SG48_RS09195 1840396 1841739 + NADP-specific glutamate dehydrogenase converts 2-oxoglutarate to glutamate%3B in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction%3B uses NADPH%3B forms a homohexamer gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09195 SG48_RS09200 SG48_1803 SG48_RS09200 1841856 1842896 - hypothetical protein gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09200 SG48_RS09205 SG48_1804 SG48_RS09205 1843024 1844985 - DNA topoisomerase 3 decatenates replicating daughter chromosomes gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09205 SG48_RS09210 SG48_1805 SG48_RS09210 1844990 1846033 - selenophosphate synthase catalyzes the formation of selenophosphate from selenide and ATP gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09210 SG48_RS09215 SG48_RS09215 SG48_RS09215 1845975 1846124 - hypothetical protein gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09215 SG48_RS09220 SG48_1806 SG48_RS09220 1846150 1846701 - oxidoreductase gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09220 SG48_RS09225 SG48_RS09225 SG48_RS09225 1846755 1846919 + hypothetical protein gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09225 SG48_RS09230 SG48_1807 SG48_RS09230 1846862 1848718 + protease 4 SppA%3B catalyzes the degradation of cleaved signal peptides%3B essential to maintain secretion of mature proteins across the membrane gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09230 SG48_RS09235 SG48_1808 ansA ansA 1848885 1849901 + L-asparaginase 1 converts asparagine to aspartate and ammonia gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09235 SG48_RS09240 SG48_1809 SG48_RS09240 1849912 1850553 + pyrazinamidase/nicotinamidase catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09240 SG48_RS09245 SG48_1810 SG48_RS09245 1850646 1852004 - metabolite transporter gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09245 SG48_RS09250 SG48_1811 SG48_RS09250 1852121 1852879 - DeoR family transcriptional regulator gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09250 SG48_RS09255 SG48_1812 SG48_RS09255 1853016 1853996 - oxidoreductase gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09255 SG48_RS09260 SG48_1813 SG48_RS09260 1854006 1854953 - kinase gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09260 SG48_RS09265 SG48_1814 SG48_RS09265 1854958 1855794 - hypothetical protein gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09265 SG48_RS09270 SG48_1815 SG48_RS09270 1855815 1856858 - Zn-dependent NAD(P)-binding oxidoreductase gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09270 SG48_RS09275 SG48_1816 SG48_RS09275 1856875 1858254 - MFS sugar transporter membrane protein gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09275 SG48_RS09280 SG48_1817 SG48_RS09280 1858281 1859357 - Zn-dependent NAD(P)-binding oxidoreductase gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09280 SG48_RS09285 SG48_1818 SG48_RS09285 1859727 1859999 - DUF1315 domain-containing protein gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09285 SG48_RS09290 SG48_1819 SG48_RS09290 1860041 1860454 - peptide methionine sulfoxide reductase MsrB gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09290 SG48_RS09295 SG48_1820 SG48_RS09295 1860796 1861791 + glyceraldehyde-3-phosphate dehydrogenase gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09295 SG48_RS09300 SG48_1821 SG48_RS09300 1861875 1862759 + D-hexose-6-phosphate epimerase-like protein gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09300 SG48_RS09305 SG48_1822 SG48_RS09305 1862807 1863661 - aldo-keto reductase gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09305 SG48_RS09310 SG48_1823 SG48_RS09310 1863751 1864497 - MltA-interacting protein scaffolding protein for the murein polymerase MrcB and the lytic transglycosylase MltA gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09310 SG48_RS09315 SG48_1824 SG48_RS09315 1864933 1866867 + protein kinase endogenous substrate unidentified%3B autokinase gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09315 SG48_RS09320 SG48_1825 SG48_RS09320 1866980 1868263 + hypothetical protein gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09320 SG48_RS09325 SG48_1826 SG48_RS09325 1868551 1869885 + membrane protein gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09325 SG48_RS09330 SG48_1827 SG48_RS09330 1870066 1871556 + diguanylate cyclase gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09330 SG48_RS09335 SG48_1828 SG48_RS09335 1871599 1872102 + aminoacyl-tRNA editing domain protein gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09335 SG48_RS09340 SG48_RS09340 SG48_RS09340 1872103 1872255 - hypothetical protein gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09340 SG48_RS09345 SG48_1830 SG48_RS09345 1872377 1872823 + membrane protein gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09345 SG48_RS09350 SG48_1831 SG48_RS09350 1872780 1873601 - transcriptional regulator gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09350 SG48_RS09355 SG48_1832 SG48_RS09355 1873698 1874879 + transporter gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09355 SG48_RS09360 SG48_1833 SG48_RS09360 1874934 1875281 + DUF488 domain-containing protein gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09360 SG48_RS09365 SG48_1834 SG48_RS09365 1875303 1875557 - DUF333 domain-containing protein gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09365 SG48_RS09370 SG48_1835 SG48_RS09370 1875740 1876765 + diguanylate cyclase gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09370 SG48_RS09375 SG48_1836 SG48_RS09375 1876798 1876896 + hypothetical protein gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09375 SG48_RS09380 SG48_1838 SG48_RS09380 1877032 1877280 - membrane protein gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09380 SG48_RS09385 SG48_1839 SG48_RS09385 1877428 1877610 - hypothetical protein gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09385 SG48_RS09390 SG48_1840 SG48_RS09390 1877614 1877973 - hypothetical protein gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09390 SG48_RS09395 SG48_1841 SG48_RS09395 1878146 1878784 - leucine efflux protein gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09395 SG48_RS09400 SG48_1842 SG48_RS09400 1878911 1879834 - transcriptional regulator gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09400 SG48_RS09405 SG48_1843 SG48_RS09405 1879937 1881022 + malate dehydrogenase gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09405 SG48_RS09410 SG48_1844 SG48_RS09410 1881228 1882658 + betaine/carnitine/choline BCCT transporter member of the betaine%2C carnitine%2C choline transporter (BCCT) family%3B unknown function gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09410 SG48_RS09415 SG48_1845 SG48_RS09415 1882690 1883814 + ring hydroxylating dioxygenase subunit alpha gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09415 SG48_RS09420 SG48_1846 SG48_RS09420 1883870 1884835 + YeaWX dioxygenase subunit beta%2C reductase component gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09420 SG48_RS09425 SG48_1847 SG48_RS09425 1884889 1886004 - ribonuclease D gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09425 SG48_RS09430 SG48_1848 SG48_RS09430 1886086 1887804 - long-chain fatty acid--CoA ligase Activates fatty acids by binding to coenzyme A gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09430 SG48_RS09435 SG48_1849 SG48_RS09435 1887976 1888557 - Slp family lipoprotein%2C RpoE-regulated gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09435 SG48_RS09440 SG48_1850 SG48_RS09440 1888597 1889292 - tRNA threonylcarbamoyladenosine biosynthesis protein TsaB gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09440 SG48_RS09445 SG48_1851 SG48_RS09445 1889350 1891260 - ATP-dependent helicase gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09445 SG48_RS09450 SG48_1852 SG48_RS09450 1891392 1891736 + hypothetical protein gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09450 SG48_RS09455 SG48_1853 SG48_RS09455 1892158 1892457 + DUF1889 domain-containing protein gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09455 SG48_RS09460 SG48_1854 SG48_RS09460 1892577 1892756 - hypothetical protein gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09460 SG48_RS09465 SG48_1855 pabB pabB 1892830 1894191 + aminodeoxychorismate synthase component I para-aminobenzoate synthase component 1%3B catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and L-glutamine gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09465 SG48_RS09470 SG48_1856 SG48_RS09470 1894195 1894773 + CoA pyrophosphohydrolase weak 3-phosphohydroxypyruvate phosphatase gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09470 SG48_RS09475 SG48_1857 SG48_RS09475 1894957 1896321 + L-serine dehydratase 1 catalyzes the formation of pyruvate from serine gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09475 SG48_RS09480 SG48_1858 SG48_RS09480 1896452 1898050 + cyclic-di-GMP phosphodiesterase gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09480 SG48_RS09485 SG48_1859 SG48_RS09485 1898054 1899610 - hypothetical protein gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09485 SG48_RS09490 SG48_RS09490 SG48_RS09490 1899598 1899807 - hypothetical protein gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09490 SG48_RS09495 SG48_1860 SG48_RS09495 1900073 1901044 + PTS mannose EIIAB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09495 SG48_RS09500 SG48_1861 SG48_RS09500 1901107 1901907 + mannose permease IIC component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09500 SG48_RS09505 SG48_1862 SG48_RS09505 1901920 1902771 + mannose permease IID component hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09505 SG48_RS09510 SG48_1863 SG48_RS09510 1902826 1903284 + hypothetical protein gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09510 SG48_RS09515 SG48_RS09515 SG48_RS09515 1903471 1903716 + hypothetical protein gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09515 SG48_RS09520 SG48_1864 SG48_RS09520 1903713 1904279 + membrane protein membrane protein YebN gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09520 SG48_RS09525 SG48_1865 rrmA rrmA 1904276 1905085 - 23S rRNA (guanine(745)-N(1))-methyltransferase methylates the guanosine in position 745 of 23S rRNA%3B required for translation and cell growth gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09525 SG48_RS09530 SG48_1866 SG48_RS09530 1905251 1905460 - cold-shock protein CspC gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09530 SG48_RS09535 SG48_1867 SG48_RS09535 1905473 1905616 - DUF2527 domain-containing protein gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09535 SG48_RS09540 SG48_RS09540 SG48_RS09540 1905578 1905784 + hypothetical protein gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09540 SG48_RS09545 SG48_1868 SG48_RS09545 1906286 1906573 - hypothetical protein gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09545 SG48_RS09550 SG48_1869 SG48_RS09550 1906648 1906791 - PhoP family transcriptional regulator gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09550 SG48_RS09555 SG48_1870 SG48_RS09555 1906950 1907189 + hypothetical protein gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09555 SG48_RS09560 SG48_1871 SG48_RS09560 1907333 1908124 - transcriptional regulator KdgR regulates the genes involved in 2-keto-3-deoxy gluconate transport and catabolism gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09560 SG48_RS09565 SG48_1872 SG48_RS09565 1908301 1909674 + transporter gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09565 SG48_RS09570 SG48_1873 SG48_RS09570 1909720 1910601 - protease HtpX metalloprotease gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09570 SG48_RS09575 SG48_1874 SG48_RS09575 1910793 1912841 - tail-specific protease Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09575 SG48_RS09580 SG48_1875 SG48_RS09580 1912861 1913559 - RNA chaperone ProQ affects solute and DNA transport through an unknown mechanism gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09580 SG48_RS09585 SG48_1876 SG48_RS09585 1913656 1914153 - methionine-R-sulfoxide reductase gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09585 SG48_RS09590 SG48_1877 SG48_RS09590 1914283 1915566 + hypothetical protein gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09590 SG48_RS09595 SG48_1878 SG48_RS09595 1915535 1918168 + MCE domain protein gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09595 SG48_RS09600 SG48_1879 yebU yebU 1918248 1919687 + ribosomal RNA small subunit methyltransferase F in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09600 SG48_RS09605 SG48_1880 SG48_RS09605 1919805 1920041 + hypothetical protein gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09605 SG48_RS09610 SG48_1881 SG48_RS09610 1920146 1920337 + hypothetical protein gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09610 SG48_RS09615 SG48_1882 SG48_RS09615 1920338 1920994 - serine/threonine-protein phosphatase 1 gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09615 SG48_RS09620 SG48_RS09620 SG48_RS09620 1921219 1921305 - hypothetical protein gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09620 SG48_RS09625 SG48_1885 SG48_RS09625 1921390 1921728 - hypothetical protein gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09625 SG48_RS09630 SG48_1886 SG48_RS09630 1921744 1922616 - hypothetical protein gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09630 SG48_RS09635 SG48_1887 SG48_RS09635 1922620 1922994 - hypothetical protein gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09635 SG48_RS09640 SG48_1888 SG48_RS09640 1923133 1923363 + DNA polymerase III subunit theta gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09640 SG48_RS09645 SG48_1889 SG48_RS09645 1923465 1924121 + hypothetical protein gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09645 SG48_RS09650 SG48_1890 SG48_RS09650 1924145 1924807 + exodeoxyribonuclease 10 3'-5' exonuclease activity on single or double-strand DNA gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09650 SG48_RS09655 SG48_1891 SG48_RS09655 1924804 1926864 - protease 2 PtrB%3B oligopeptidase that cleaves peptide bonds following arginine and lysine residues gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09655 SG48_RS09660 SG48_1892 SG48_RS09660 1927073 1927732 - hypothetical protein gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09660 SG48_RS09665 SG48_RS09665 SG48_RS09665 1927792 1927902 + hypothetical protein gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09665 SG48_RS09670 SG48_1893 SG48_RS09670 1928059 1928415 - hypothetical protein secreted protein%3B unknown function gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09670 SG48_RS09675 SG48_1894 SG48_RS09675 1928482 1928772 - DNA damage-inducible protein gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09675 SG48_RS09680 SG48_1895 SG48_RS09680 1928906 1930084 + phosphoribosylglycinamide formyltransferase 2 gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09680 SG48_RS09685 SG48_1896 SG48_RS09685 1930140 1930781 - KHG/KDPG aldolase catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate%3B or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09685 SG48_RS09690 SG48_1897 SG48_RS09690 1930818 1932629 - phosphogluconate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09690 SG48_RS09695 SG48_1898 SG48_RS09695 1932864 1934339 - glucose-6-phosphate 1-dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09695 SG48_RS09700 SG48_RS09700 SG48_RS09700 1934505 1934654 - hypothetical protein gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09700 SG48_RS09705 SG48_1899 SG48_RS09705 1934677 1935546 + transcriptional regulator Represses the expression of the zwf%2C eda%2C glp and gap gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09705 SG48_RS09710 SG48_1900 SG48_RS09710 1935674 1937116 + pyruvate kinase II catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09710 SG48_RS09715 SG48_1901 SG48_RS09715 1937247 1938218 - lipid A biosynthesis myristoyltransferase Transfers myristate or laurate%2C activated on ACP%2C to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09715 SG48_RS09720 SG48_1902 SG48_RS09720 1938338 1939660 - murein DD-endopeptidase MepM gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09720 SG48_RS09725 SG48_1903 znuA znuA 1939676 1940608 - zinc uptake system protein ZnuA involved in transport of zinc(II) with ZnuA and C gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09725 SG48_RS09730 SG48_1904 znuC znuC 1940687 1941442 + Mn2+/Zn2+ABC transporter ATP-binding protein involved in transport of zinc(II) with ZnuA and C gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09730 SG48_RS09735 SG48_1905 znuB znuB 1941439 1942224 + zinc uptake system membrane protein ZnuB involved in transport of zinc(II) with ZnuA and C gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09735 SG48_RS09740 SG48_1906 SG48_RS09740 1942371 1943381 - Holliday junction DNA helicase RuvB gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09740 SG48_RS09745 SG48_1907 ruvA ruvA 1943390 1944001 - Holliday junction DNA helicase RuvA plays an essential role in ATP-dependent branch migration of the Holliday junction gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09745 SG48_RS09750 SG48_1909 SG48_RS09750 1944276 1944878 + DUF830 domain-containing protein gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09750 SG48_RS09755 SG48_1910 ruvC ruvC 1944880 1945401 - crossover junction endodeoxyribonuclease RuvC endonuclease%3B resolves Holliday structures%3B forms a complex of RuvABC%3B the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration%3B RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09755 SG48_RS09760 SG48_1911 SG48_RS09760 1945436 1946176 - transcriptional regulator gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09760 SG48_RS09765 SG48_1912 nudB nudB 1946205 1946687 - dihydroneopterin triphosphate pyrophosphatase catalyzes the formation of dihydroneopterin phosphate from dihydroneopterin triphosphate gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09765 SG48_RS09770 SG48_1913 SG48_RS09770 1946775 1948547 - aspartate--tRNA ligase gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09770 SG48_RS09775 SG48_1914 SG48_RS09775 1948857 1949423 + isochorismatase gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09775 SG48_RS09780 SG48_1915 SG48_RS09780 1949420 1950238 + hypothetical protein gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09780 SG48_RS09785 SG48_1916 SG48_RS09785 1950291 1950686 + hypothetical protein gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09785 SG48_RS09790 SG48_1917 SG48_RS09790 1950727 1951470 + tRNA (cmo5U34)-methyltransferase catalyzes the conversion of 5-methoxyuridine to uridine-5-oxyacetic acid in tRNA gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09790 SG48_RS09795 SG48_1918 SG48_RS09795 1951467 1952438 + tRNA (mo5U34)-methyltransferase catalyzes the conversion of 5-hydroxyuridine to 5-methoxyuridine in tRNA gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09795 SG48_RS09800 SG48_1919 SG48_RS09800 1952603 1955032 - Trimethylamine-N-oxide reductase 2 catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09800 SG48_RS09805 SG48_1920 SG48_RS09805 1955057 1956157 - cytochrome c-type protein TorY gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09805 SG48_RS09810 SG48_1921 SG48_RS09810 1956545 1957291 - copper homeostasis protein CutC gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09810 SG48_RS09815 SG48_1922 SG48_RS09815 1957305 1957871 - hypothetical protein gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09815 SG48_RS09820 SG48_1923 SG48_RS09820 1958087 1959820 + arginine--tRNA ligase gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09820 SG48_RS09825 SG48_1924 SG48_RS09825 1959997 1960485 + hypothetical protein gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09825 SG48_RS09830 SG48_1925 SG48_RS09830 1960605 1960997 - flagellar biosynthesis protein FlhE gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09830 SG48_RS09835 SG48_1926 SG48_RS09835 1960997 1963075 - flagellar biosynthesis protein FlhA gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09835 SG48_RS09840 SG48_1927 flhB flhB 1963068 1964216 - flagellar biosynthetic protein FlhB membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09840 SG48_RS09845 SG48_1928 SG48_RS09845 1964418 1965062 - protein phosphatase CheZ cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09845 SG48_RS09850 SG48_1929 SG48_RS09850 1965073 1965462 - chemotaxis protein CheY chemotaxis regulator that%2C when phosphorylated%2C interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09850 SG48_RS09855 SG48_1930 SG48_RS09855 1965477 1966526 - two-component system protein-glutamate methylesterase response regulator regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09855 SG48_RS09860 SG48_1931 SG48_RS09860 1966529 1967389 - chemotaxis protein methyltransferase methylates the MCP gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09860 SG48_RS09865 SG48_1932 SG48_RS09865 1967408 1969009 - methyl-accepting chemotaxis protein IV mediates taxis toward dipeptides gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09865 SG48_RS09870 SG48_1933 SG48_RS09870 1969055 1970716 - methyl-accepting chemotaxis protein II serine sensor receptor gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09870 SG48_RS09875 SG48_1934 SG48_RS09875 1970861 1971364 - chemotaxis protein CheW gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09875 SG48_RS09880 SG48_1935 SG48_RS09880 1971385 1973343 - chemotaxis protein CheA gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09880 SG48_RS09885 SG48_1936 motB motB 1973354 1974280 - motility protein B with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09885 SG48_RS09890 SG48_1937 SG48_RS09890 1974277 1975164 - motility protein A With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09890 SG48_RS09895 SG48_1938 SG48_RS09895 1975291 1975869 - flagellar transcriptional regulator FlhC With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09895 SG48_RS09900 SG48_1939 SG48_RS09900 1975872 1976222 - flagellar transcriptional regulator FlhD with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09900 SG48_RS09905 SG48_1940 SG48_RS09905 1977002 1977430 + universal stress protein C ppGpp-dependent%3B membrane-associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09905 SG48_RS09910 SG48_1941 SG48_RS09910 1977437 1978861 - alpha%2Calpha-trehalose-phosphate synthase [UDP-forming] gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09910 SG48_RS09915 SG48_1942 SG48_RS09915 1978836 1979636 - trehalose-6-phosphate phosphatase biosynthetic%3B catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate%3B expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09915 SG48_RS09920 SG48_1943 araH araH 1979803 1980789 - arabinose ABC transporter permease Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09920 SG48_RS09925 SG48_1944 araG araG 1980804 1982318 - arabinose import ATP-binding protein AraG Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09925 SG48_RS09930 SG48_1945 SG48_RS09930 1982388 1983377 - L-arabinose-binding periplasmic protein with AraGH is involved in the transport of arabinose into the cell gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09930 SG48_RS09935 SG48_1946 SG48_RS09935 1984174 1984677 + non-heme ferritin ferritin B%3B required for virulence in Salmonella%3B may be involved in repair of damaged Fe-S clusters gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09935 SG48_RS09940 SG48_1947 SG48_RS09940 1984756 1985007 - hypothetical protein gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09940 SG48_RS09945 SG48_RS09945 SG48_RS09945 1985119 1985265 + hypothetical protein gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09945 SG48_RS09950 SG48_1949 SG48_RS09950 1985471 1985794 + lipoprotein%2C function unknown gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09950 SG48_RS09955 SG48_1950 SG48_RS09955 1985965 1986462 + non-heme ferritin cytoplasmic iron storage protein gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09955 SG48_RS09960 SG48_1951 SG48_RS09960 1986500 1986739 - DUF2492 domain-containing protein gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09960 SG48_RS09965 SG48_1952 SG48_RS09965 1986930 1988141 + tyrosine-specific transporter tyrosine specific permease gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09965 SG48_RS09970 SG48_1953 SG48_RS09970 1988203 1988868 - hypothetical protein gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09970 SG48_RS09975 SG48_1954 SG48_RS09975 1989064 1989150 - tRNA-Leu tRNA gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09975 SG48_RS09980 SG48_1955 SG48_RS09980 1989163 1989236 - tRNA-Cys tRNA gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09980 SG48_RS09985 SG48_1956 SG48_RS09985 1989291 1989366 - tRNA-Gly tRNA gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09985 SG48_RS09990 SG48_1957 SG48_RS09990 1989518 1990066 - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09990 SG48_RS09995 SG48_1958 uvrC uvrC 1990123 1991955 - UvrABC system protein C The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS09995 SG48_RS10000 SG48_1959 sirA sirA 1991952 1992608 - transcriptional regulator in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system%3B in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10000 SG48_RS10005 SG48_RS10005 SG48_RS10005 1992904 1993080 + 2-oxo acid dehydrogenase gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10005 SG48_RS10010 SG48_1960 SG48_RS10010 1993067 1993291 + hypothetical protein gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10010 SG48_RS10015 SG48_1961 SG48_RS10015 1993359 1994081 - regulatory protein SdiA regulates genes involved in cell division gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10015 SG48_RS10020 SG48_1962 SG48_RS10020 1994311 1995063 - ABC transporter ATPase gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10020 SG48_RS10025 SG48_1963 SG48_RS10025 1995060 1995728 - amino acid ABC transporter permease gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10025 SG48_RS10030 SG48_1964 SG48_RS10030 1995743 1996729 - D-cysteine desulfhydrase catalyzes the formation of pyruvate from D-cysteine gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10030 SG48_RS10035 SG48_1965 SG48_RS10035 1996834 1997634 - cystine-binding periplasmic protein gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10035 SG48_RS10040 SG48_1966 SG48_RS10040 1997722 1998273 - regulator of sigma S factor FliZ expression activator of the class 2 type of flagellar operons%2C essential to achieve maximal cell motility%3B activator of type 1 fimbrial gene expression%3B cell density-responsive regulator%3B FliZ in Salmonella typhimurium induces HilA%2C an activator of invasion genes necessary to achieve full virulence gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10040 SG48_RS10045 SG48_1967 fliA fliA 1998319 1999038 - RNA polymerase sigma factor FliA sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor directs late flagellar biosynthesis genes gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10045 SG48_RS10050 SG48_1968 SG48_RS10050 1999359 2000855 - flagellin structural flagella protein%3B individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella%2C termed phase 1 and phase 2%2C each specified by separate structural genes gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10050 SG48_RS10055 SG48_1969 fliD fliD 2001121 2002527 + flagellar hook-associated protein 2 involved in flagellin assembly gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10055 SG48_RS10060 SG48_1970 fliS fliS 2002552 2002962 + flagellar protein FliS flagellin specific chaperone gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10060 SG48_RS10065 SG48_1971 SG48_RS10065 2002962 2003327 + flagellar protein FliT binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway%3B acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription%3B member of the type III cytoplasmic chaperone family gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10065 SG48_RS10070 SG48_1972 SG48_RS10070 2003405 2004892 + alpha-amylase converts 1%2C4-alpha-D-glucans to maltodextrin gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10070 SG48_RS10075 SG48_1973 SG48_RS10075 2004926 2005339 - lipoprotein gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10075 SG48_RS10080 SG48_1974 SG48_RS10080 2005526 2006731 + UPF0394 family sulfur transport domain-containing inner membrane protein gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10080 SG48_RS10085 SG48_1975 SG48_RS10085 2006728 2006961 + TusA family sulfurtransferase gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10085 SG48_RS10090 SG48_1976 SG48_RS10090 2007070 2007738 + DUF159 domain-containing protein gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10090 SG48_RS10095 SG48_1977 SG48_RS10095 2007849 2008328 + GNAT family acetyltransferase gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10095 SG48_RS10100 SG48_RS10100 SG48_RS10100 2008472 2008701 - non-LEE-encoded type III secreted effector domain protein gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10100 SG48_RS10105 SG48_RS10105 SG48_RS10105 2008798 2009600 - hypothetical protein gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10105 SG48_RS10110 SG48_RS10110 SG48_RS10110 2009751 2010029 + hypothetical protein gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10110 SG48_RS10115 SG48_1980 fliE fliE 2009949 2010263 - flagellar hook-basal body complex protein FliE forms a junction between the M-ring and FlgB during flagella biosynthesis gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10115 SG48_RS10120 SG48_1981 fliF fliF 2010478 2012136 + flagellar M-ring protein the MS-ring anchors the flagellum to the cytoplasmic membrane%3B part of the flagellar basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10120 SG48_RS10125 SG48_1982 fliG fliG 2012129 2013124 + flagellar motor switch protein FliG One of three proteins involved in switching the direction of the flagellar rotation gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10125 SG48_RS10130 SG48_1983 fliH fliH 2013117 2013803 + flagellar assembly protein FliH binds to and inhibits the function of flagella specific ATPase FliI gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10130 SG48_RS10135 SG48_1984 fliI fliI 2013803 2015176 + flagellum-specific ATP synthase involved in type III protein export during flagellum assembly gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10135 SG48_RS10140 SG48_1985 fliJ fliJ 2015195 2015638 + flagellar FliJ protein rod/hook and filament chaperone gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10140 SG48_RS10145 SG48_1986 SG48_RS10145 2015635 2016762 + flagellar hook-length control protein gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10145 SG48_RS10150 SG48_1987 fliL fliL 2016867 2017331 + flagellar protein FliL interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10150 SG48_RS10155 SG48_1988 fliM fliM 2017336 2018340 + flagellar motor switch protein FliM with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10155 SG48_RS10160 SG48_1989 fliN fliN 2018337 2018750 + flagellar motor switch protein FliN One of three proteins involved in switching the direction of the flagellar rotation gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10160 SG48_RS10165 SG48_1990 SG48_RS10165 2018753 2019118 + flagellar protein FliO with FlhA%2C FlhB%2C FliP%2C FliQ and FliR is one of the membrane components of the flagellar export apparatus gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10165 SG48_RS10170 SG48_1991 fliP fliP 2019118 2019855 + flagellar biosynthetic protein FliP FliP%2C with proteins FliQ and FliR%2C forms the core of the central channel in the flagella export apparatus gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10170 SG48_RS10175 SG48_1992 fliQ fliQ 2019865 2020134 + flagellar biosynthetic protein FliQ with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10175 SG48_RS10180 SG48_1993 fliR fliR 2020142 2020927 + flagellar biosynthesis protein FliR FliR%2C with proteins FliP and FliQ%2C forms the core of the central channel in the flagella export apparatus gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10180 SG48_RS10185 SG48_1994 rcsA rcsA 2021217 2021840 + transcriptional regulator with RcsB is a positive regulator of capsular polysaccharide synthesis genes gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10185 SG48_RS10190 SG48_1995 SG48_RS10190 2021884 2022072 - protein DsrB gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10190 SG48_RS10195 SG48_1996 SG48_RS10195 2022235 2022462 + hypothetical protein gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10195 SG48_RS10200 SG48_1998 SG48_RS10200 2022760 2023575 + mannosyl-3-phosphoglycerate phosphatase catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10200 SG48_RS10205 SG48_1999 SG48_RS10205 2023572 2025248 - diguanylate cyclase catalyzes the formation of cyclic di-3'%2C5'-guanylate from guanosine triphosphate%3B involved in the regulation of cellulose biosynthesis gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10205 SG48_RS10210 SG48_2000 SG48_RS10210 2025437 2025619 - hypothetical protein gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10210 SG48_RS10215 SG48_2001 SG48_RS10215 2025698 2026615 - hypothetical protein gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10215 SG48_RS10220 SG48_2002 SG48_RS10220 2026788 2027708 + amino acid exporter for phenylalanine%2C threonine gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10220 SG48_RS10225 SG48_2003 SG48_RS10225 2027697 2028167 - very short patch repair protein DNA mismatch endonuclease%3B recognizes and repairs T:G mismatches gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10225 SG48_RS10230 SG48_2004 SG48_RS10230 2028148 2029566 - DNA-cytosine methyltransferase gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10230 SG48_RS10235 SG48_2005 SG48_RS10235 2029633 2030328 - hydrolase gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10235 SG48_RS10240 SG48_2006 SG48_RS10240 2030368 2030670 - permease gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10240 SG48_RS10250 SG48_RS10250 SG48_RS10250 2031300 2032492 + porin allows for ions and hydrophilic solutes to cross the outer membrane gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10250 SG48_RS10255 SG48_RS10255 SG48_RS10255 2032493 2032696 - hypothetical protein gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10255 SG48_RS10260 SG48_2009 SG48_RS10260 2033084 2033935 + Molecular chaperone Hsp31 and glyoxalase 3 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10260 SG48_RS10265 SG48_2010 SG48_RS10265 2034043 2035401 - two-component system sensor histidine kinase gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10265 SG48_RS10270 SG48_2011 SG48_RS10270 2035401 2036072 - two-component system response regulator induced by CusR in the presence of copper%3B YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW%3B yedVW is one of four copper regulons found in E. coli%3B part of the copper homeostasis mechanism%3B confers resistance to copper and several drugs when induced gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10270 SG48_RS10275 SG48_2012 SG48_RS10275 2036205 2036618 + 5-hydroxyisourate hydrolase catalyzes the formation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline from 5-hydroxyisourate gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10275 SG48_RS10280 SG48_2013 SG48_RS10280 2036727 2037731 + sulfoxide reductase catalytic subunit YedY in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase%3B requires inner membrane anchor protein YedZ gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10280 SG48_RS10285 SG48_2014 SG48_RS10285 2037732 2038367 + sulfoxide reductase heme-binding subunit YedZ in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY%3B sulfite oxidase activity not demonstrated%3B contains heme gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10285 SG48_RS10290 SG48_2015 SG48_RS10290 2038624 2039274 + metal-binding protein ZinT gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10290 SG48_RS10295 SG48_2016 SG48_RS10295 2039617 2040147 + cytochrome b561 homolog 1 gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10295 SG48_RS10300 SG48_RS10300 SG48_RS10300 2040170 2040412 + hypothetical protein gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10300 SG48_RS10305 SG48_2017 SG48_RS10305 2040717 2040806 - tRNA-Ser tRNA gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10305 SG48_RS10310 SG48_2018 SG48_RS10310 2040900 2041697 + protein MtfA Mlc anti-repressor%3B regulates ptsG by binding and inactivating Mlc gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10310 SG48_RS10315 SG48_2019 SG48_RS10315 2041798 2041873 + tRNA-Asn tRNA gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10315 SG48_RS10320 SG48_2020 SG48_RS10320 2042187 2049263 + adhesin gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10320 SG48_RS10325 SG48_RS10325 SG48_RS10325 2049525 2050577 - hypothetical protein gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10325 SG48_RS10330 SG48_2022 SG48_RS10330 2050892 2052208 + shikimate transporter gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10330 SG48_RS10335 SG48_2023 SG48_RS10335 2052310 2053764 + AMP nucleosidase Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10335 SG48_RS10340 SG48_2024 SG48_RS10340 2054107 2054823 + transcriptional regulator gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10340 SG48_RS10345 SG48_2025 SG48_RS10345 2055276 2055351 - tRNA-Asn tRNA gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10345 SG48_RS10350 SG48_2026 SG48_RS10350 2055452 2056906 - MATE family multidrug exporter gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10350 SG48_RS10355 SG48_2027 SG48_RS10355 2057100 2057175 + tRNA-Asn tRNA gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10355 SG48_RS10360 SG48_2028 cbl cbl 2057213 2058163 - transcriptional regulator LysR-type transcriptional regulator similar to CysB%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon%3B regulated by CysB%3B DNA-binding transcriptional activator for the ssuEADCB and tauABCD operons gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10360 SG48_RS10365 SG48_2029 SG48_RS10365 2058265 2059182 - nitrogen assimilation regulatory protein nac Transcriptional activator for the hut%2C put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10365 SG48_RS10370 SG48_2030 SG48_RS10370 2059509 2059584 + tRNA-Asn tRNA gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10370 SG48_RS10375 SG48_2031 SG48_RS10375 2059640 2060572 - transpeptidase catalyzes th removal of D-alanine and attachment of the murein lipoprotein to the peptidoglycan tetrapeptide chain gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10375 SG48_RS10380 SG48_2032 cobT cobT 2060637 2061716 - nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5%2C6-dimethylbenzimidazole gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10380 SG48_RS10385 SG48_2033 cobS cobS 2061728 2062471 - adenosylcobinamide-GDP ribazoletransferase catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10385 SG48_RS10390 SG48_2034 cobU cobU 2062468 2063013 - cobalamin biosynthesis protein CobU catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10390 SG48_RS10400 SG48_2036 SG48_RS10400 2063554 2064534 - transposase gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10400 SG48_RS10405 SG48_RS10405 SG48_RS10405 2064677 2064841 - hypothetical protein gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10405 SG48_RS10410 SG48_2040 SG48_RS10410 2066201 2067106 - integrase gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10410 SG48_RS10415 SG48_2041 SG48_RS10415 2067064 2067429 - transposase represses IS2 gene transcription gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10415 SG48_RS10420 SG48_RS10420 SG48_RS10420 2067493 2067753 + TonB-dependent receptor gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10420 SG48_RS10425 SG48_RS10425 SG48_RS10425 2067750 2068460 + hypothetical protein gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10425 SG48_RS10430 SG48_2044 SG48_RS10430 2068788 2071907 + antigen 43 gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10430 SG48_RS10435 SG48_2045 SG48_RS10435 2072028 2073589 + hypothetical protein gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10435 SG48_RS10440 SG48_2046 SG48_RS10440 2073557 2074003 + UPF0758 protein YeeS gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10440 SG48_RS10445 SG48_2047 SG48_RS10445 2074066 2074287 + hypothetical protein gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10445 SG48_RS10450 SG48_2048 SG48_RS10450 2074361 2074729 + cytoskeleton bundling-enhancing protein CbeA gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10450 SG48_RS10455 SG48_2049 SG48_RS10455 2074818 2075192 + toxin CbtA gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10455 SG48_RS10460 SG48_RS10460 SG48_RS10460 2075189 2075383 + hypothetical protein gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10460 SG48_RS10465 SG48_RS10465 SG48_RS10465 2075396 2075509 + hypothetical protein gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10465 SG48_RS10470 SG48_RS10470 SG48_RS10470 2075998 2076180 + hypothetical protein gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10470 SG48_RS10475 SG48_2053 SG48_RS10475 2076281 2076610 - hypothetical protein gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10475 SG48_RS10480 SG48_2054 SG48_RS10480 2076782 2077840 - hypothetical protein gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10480 SG48_RS10485 SG48_2055 SG48_RS10485 2078038 2078511 - DNA gyrase inhibitor gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10485 SG48_RS10490 SG48_2056 SG48_RS10490 2078630 2079796 - D-alanyl-D-alanine carboxypeptidase removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors%3B penicillin-binding protein 6B%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10490 SG48_RS10495 SG48_2057 sbcB sbcB 2080008 2081432 + exonuclease I Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10495 SG48_RS10500 SG48_2058 SG48_RS10500 2081475 2081702 - TusA family sulfurtransferase gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10500 SG48_RS10505 SG48_2059 SG48_RS10505 2081716 2082774 - hypothetical protein gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10505 SG48_RS10510 SG48_2060 SG48_RS10510 2082953 2084311 - low-affinity putrescine importer PlaP gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10510 SG48_RS10515 SG48_2062 SG48_RS10515 2084578 2085507 - LysR family transcriptional regulator gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10515 SG48_RS10520 SG48_2063 SG48_RS10520 2085553 2086377 - hypothetical protein gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10520 SG48_RS10525 SG48_2064 SG48_RS10525 2086460 2086714 - toxin YoeB gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10525 SG48_RS10530 SG48_2065 SG48_RS10530 2086711 2086962 - antitoxin YefM Antitoxin that counteracts the effect of the YoeB toxin gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10530 SG48_RS10535 SG48_2067 hisG hisG 2087441 2088340 + ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10535 SG48_RS10540 SG48_2068 hisD hisD 2088346 2089650 + histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10540 SG48_RS10545 SG48_2069 SG48_RS10545 2089647 2090717 + histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10545 SG48_RS10550 SG48_2070 SG48_RS10550 2090717 2091784 + histidine biosynthesis bifunctional protein HisB catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10550 SG48_RS10555 SG48_2071 hisH hisH 2091784 2092374 + imidazole glycerol phosphate synthase subunit HisH with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamide ribonucleotide%2C and glutamate in histidine biosynthesis%3B the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10555 SG48_RS10560 SG48_2072 SG48_RS10560 2092374 2093111 + 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10560 SG48_RS10565 SG48_2073 SG48_RS10565 2093093 2093869 + imidazole glycerol phosphate synthase subunit HisF gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10565 SG48_RS10570 SG48_2074 SG48_RS10570 2093863 2094474 + histidine biosynthesis bifunctional protein HisIE catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10570 SG48_RS10575 SG48_2075 SG48_RS10575 2094570 2095550 - chain length determinant protein regulator of length of O-antigen component of lipopolysaccharide chains gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10575 SG48_RS10580 SG48_2076 SG48_RS10580 2095696 2096862 - UDP-glucose 6-dehydrogenase catalyzes the formation of UDP-glucuronate from UDP-glucose gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10580 SG48_RS10585 SG48_2077 SG48_RS10585 2097111 2098517 - 6-phosphogluconate dehydrogenase decarboxylating catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10585 SG48_RS10590 SG48_2079 SG48_RS10590 2099144 2100124 - transposase gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10590 SG48_RS10595 SG48_RS10595 SG48_RS10595 2100189 2100638 - rhamnosyltransferase gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10595 SG48_RS10600 SG48_2080 SG48_RS10600 2100640 2101758 - LPS biosynthesis protein gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10600 SG48_RS10605 SG48_2081 SG48_RS10605 2101743 2102333 - LPS biosynthesis protein WbbJ%3B catalyzes the transfer of the O-acetyl moiety to the O antigen%3B part of the lipopolysaccharide biosynthetic pathway gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10605 SG48_RS10610 SG48_2082 SG48_RS10610 2102314 2103306 - beta-1%2C6-galactofuranosyltransferase WbbI gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10610 SG48_RS10615 SG48_2083 SG48_RS10615 2103309 2104475 - O-antigen polymerase gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10615 SG48_RS10620 SG48_2084 SG48_RS10620 2104475 2105578 - UDP-galactopyranose mutase gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10620 SG48_RS10625 SG48_2085 SG48_RS10625 2105586 2106833 - polisoprenol-linked O-antigen transporter gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10625 SG48_RS10630 SG48_2086 SG48_RS10630 2106830 2107387 - dTDP-4-dehydrorhamnose 3%2C5-epimerase gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10630 SG48_RS10635 SG48_2087 SG48_RS10635 2107387 2108268 - glucose-1-phosphate thymidylyltransferase gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10635 SG48_RS10640 SG48_2088 SG48_RS10640 2108326 2109225 - dTDP-4-dehydrorhamnose reductase with dTDP-4-dehydrorhamnose 3%2C5-epimerase forms a complex known as dTDP-L-rhamnose synthetase%3B catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10640 SG48_RS10645 SG48_2089 SG48_RS10645 2109225 2110310 - dTDP-glucose 4%2C6-dehydratase gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10645 SG48_RS10650 SG48_2090 SG48_RS10650 2110683 2111576 - UTP--glucose-1-phosphate uridylyltransferase gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10650 SG48_RS10655 SG48_2091 wcaM wcaM 2111751 2113145 - colanic acid biosynthesis protein WcaM WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface%3B may be involved in the biosynthesis of colanic acid gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10655 SG48_RS10660 SG48_2092 SG48_RS10660 2113156 2114376 - colanic acid biosynthesis glycosyltransferase WcaL gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10660 SG48_RS10665 SG48_2093 SG48_RS10665 2114373 2115653 - colanic acid biosynthesis pyruvyl transferase WcaK gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10665 SG48_RS10670 SG48_2094 SG48_RS10670 2115929 2117407 - LPS biosynthesis protein gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10670 SG48_RS10675 SG48_2095 SG48_RS10675 2117409 2118803 - UDP-glucose--undecaprenyl-phosphate glucose-1-phosphate transferase WcaJ%3B glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10675 SG48_RS10680 SG48_2096 SG48_RS10680 2118858 2120228 - phosphomannomutase capsular polysaccharide biosynthesis protein%3B catalyzes the formation of D-mannose 6-phosphate from alpha-D-mannose 1-phosphate gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10680 SG48_RS10685 SG48_2097 cpsB cpsB 2120333 2121769 - mannose-1-phosphate guanylyltransferase capsular polysaccharide colanic acid biosynthesis protein%3B catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10685 SG48_RS10690 SG48_2098 SG48_RS10690 2121772 2122995 - glycosyl transferase gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10690 SG48_RS10695 SG48_2099 SG48_RS10695 2122992 2123471 - GDP-mannose mannosyl hydrolase catalyzes the formation of GDP and D-mannose from GDP-D-mannose%3B also hydrolyzes GDP-glucose gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10695 SG48_RS10700 SG48_2100 SG48_RS10700 2123474 2124439 - GDP-L-fucose synthase bifunctional GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase%3Bcatalyzes the formation of GDP-fucose from GDP-4-dehydro-6-deoxy-D-mannose gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10700 SG48_RS10705 SG48_2101 SG48_RS10705 2124442 2125563 - GDP-mannose 4%2C6-dehydratase catalyzes the formation of GDP-4-dehydro-6-deoxy-D-mannose from GDP mannose gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10705 SG48_RS10710 SG48_2102 SG48_RS10710 2125589 2126137 - colanic acid biosynthesis acetyltransferase WcaF gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10710 SG48_RS10715 SG48_2103 SG48_RS10715 2126153 2126899 - colanic acid biosynthesis glycosyltransferase WcaE gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10715 SG48_RS10720 SG48_2104 wcaD wcaD 2126910 2128127 - colanic acid polymerase essential for colanic acid biosynthesis%3B colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10720 SG48_RS10725 SG48_2105 SG48_RS10725 2128102 2129319 - colanic acid biosynthesis glycosyltransferase WcaC gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10725 SG48_RS10730 SG48_2106 SG48_RS10730 2129316 2129804 - colanic acid biosynthesis acetyltransferase WcaB acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit)%3B wcaB is induced in sessile bacteria and by osmotic shock%2C and repressed when grown in rich medium gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10730 SG48_RS10735 SG48_2107 SG48_RS10735 2129807 2130646 - glycosyl transferase gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10735 SG48_RS10740 SG48_2108 SG48_RS10740 2130739 2132901 - tyrosine-protein kinase wzc Wzc%3B catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10740 SG48_RS10745 SG48_2109 SG48_RS10745 2132904 2133347 - protein-tyrosine phosphatase Wzb shows phosphatase activity towards the autophosphorylated Wzc protein%2C which induces colanic acid biosynthesis%3B catalyzes the phosphorylation of UDP-glucose dehydrogenase%2C an enzyme involved in colanic acid biosynthesis gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10745 SG48_RS10750 SG48_2110 SG48_RS10750 2133353 2134492 - lipoprotein required for the translocation of capsular polysaccharide through the outer membrane gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10750 SG48_RS10755 SG48_2111 SG48_RS10755 2135151 2136734 + hypothetical protein gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10755 SG48_RS10760 SG48_2112 SG48_RS10760 2137008 2138861 - protein AsmA YegA%3B inner membrane protein involved in the assembly of outer membrane proteins (OMPs)%3B asmA-null mutants show low lipopolysaccharide (LPS) levels%2C suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity%2C resulting on altered assembly of OMPs gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10760 SG48_RS10765 SG48_2113 SG48_RS10765 2138883 2139464 - deoxycytidine triphosphate deaminase gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10765 SG48_RS10770 SG48_2114 SG48_RS10770 2139556 2140197 - uridine kinase gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10770 SG48_RS10775 SG48_2115 SG48_RS10775 2140515 2143832 + diguanylate cyclase gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10775 SG48_RS10780 SG48_2116 SG48_RS10780 2143941 2144789 - DNA-3-methyladenine glycosylase 2 inducible%2C catalyzes the hydrolysis of alkylated DNA%2C releasing 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine and 7-methyladenine gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10780 SG48_RS10785 SG48_RS10785 SG48_RS10785 2144803 2144910 - hypothetical protein gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10785 SG48_RS10790 SG48_2117 SG48_RS10790 2144923 2146275 + Hsp70 chaperone family protein gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10790 SG48_RS10795 SG48_2118 SG48_RS10795 2146288 2148234 - protein kinase-related non-specific DNA-binding protein gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10795 SG48_RS10800 SG48_2119 SG48_RS10800 2148434 2148895 + hypothetical protein gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10800 SG48_RS10805 SG48_2120 SG48_RS10805 2148960 2149640 - hypothetical protein gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10805 SG48_RS10810 SG48_2121 SG48_RS10810 2149718 2150377 - VMA domain protein gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10810 SG48_RS10815 SG48_2126 SG48_RS10815 2151265 2152512 + multidrug resistance protein MdtA Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10815 SG48_RS10820 SG48_2127 SG48_RS10820 2152512 2155634 + multidrug resistance protein MdtB Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10820 SG48_RS10825 SG48_2128 SG48_RS10825 2155635 2158712 + multidrug resistance protein MdtC Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10825 SG48_RS10830 SG48_2129 SG48_RS10830 2158713 2160128 + citrate/iron-citrate/zinc-citrate efflux transporter gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10830 SG48_RS10835 SG48_2130 SG48_RS10835 2160125 2161528 + two-component system sensor histidine kinase gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10835 SG48_RS10840 SG48_2131 SG48_RS10840 2161525 2162247 + two-component system response regulator response regulator in two-component regulatory system with BaeS%3B regulator of RNA synthesis%2C flagellar biosynthesis%2C chemotaxis and transport gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10840 SG48_RS10845 SG48_2132 SG48_RS10845 2162438 2162770 + hypothetical protein gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10845 SG48_RS10850 SG48_2133 SG48_RS10850 2162917 2164278 + protease gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10850 SG48_RS10860 SG48_RS10860 SG48_RS10860 2164984 2165250 - hypothetical protein gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10860 SG48_RS10865 SG48_2137 SG48_RS10865 2165238 2165570 - hypothetical protein gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10865 SG48_RS10870 SG48_2138 SG48_RS10870 2165961 2166860 + phosphatidylglycerol kinase metal-dependent cytosolic protein with phosphatidylglycerol kinase activity%3B undetermined physiological role gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10870 SG48_RS10875 SG48_RS10875 SG48_RS10875 2166942 2167388 - DeoR family transcriptional regulator gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10875 SG48_RS10880 SG48_2140 SG48_RS10880 2167485 2167784 + transposase gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10880 SG48_RS10885 SG48_2141 SG48_RS10885 2167781 2168647 + transposase gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10885 SG48_RS10890 SG48_RS10890 SG48_RS10890 2168677 2168982 - transcriptional regulator gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10890 SG48_RS10895 SG48_2142 SG48_RS10895 2169082 2170122 - galactitol-1-phosphate 5-dehydrogenase Zn-dependent%3B NAD(P)-binding%3B catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10895 SG48_RS10900 SG48_2143 SG48_RS10900 2170170 2171525 - galactitol permease IIC component gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10900 SG48_RS10905 SG48_2144 SG48_RS10905 2171529 2171813 - galactitol-specific phosphotransferase enzyme IIB component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10905 SG48_RS10910 SG48_2145 SG48_RS10910 2171844 2172296 - galactitol-specific phosphotransferase enzyme IIA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10910 SG48_RS10915 SG48_2146 SG48_RS10915 2172306 2173568 - tagatose-1%2C6-bisphosphate aldolase part of the galacitol catabolism pathway%3B with GatY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1%2C6-bisphosphate gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10915 SG48_RS10920 SG48_2147 gatY gatY 2173597 2174451 - tagatose-1%2C6-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10920 SG48_RS10925 SG48_2148 SG48_RS10925 2174759 2175811 - fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1%2C6-bisphosphate gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10925 SG48_RS10930 SG48_2149 SG48_RS10930 2176068 2177345 + nucleoside transporter low affinity gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10930 SG48_RS10935 SG48_2150 SG48_RS10935 2177342 2178346 + ADP-ribosylglycohydrolase gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10935 SG48_RS10940 SG48_2151 SG48_RS10940 2178343 2179308 + kinase gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10940 SG48_RS10945 SG48_2152 SG48_RS10945 2179282 2180028 - transcriptional regulator gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10945 SG48_RS10950 SG48_2153 SG48_RS10950 2180080 2180898 - family 25 glycosyl hydrolase gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10950 SG48_RS10955 SG48_2154 SG48_RS10955 2180963 2181763 - hydroxymethylpyrimidine/phosphomethylpyrimidine kinase catalyzes the formation hydroxymethylpyrimidine phosphate from hydroxymethylpyrimidine and the formation of of 4-amino-2-methyl-5-diphosphomethylpyrimidine from hydroxymethylpyrimidine phosphate gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10955 SG48_RS10960 SG48_2155 SG48_RS10960 2181760 2182548 - hydroxyethylthiazole kinase gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10960 SG48_RS10965 SG48_2156 SG48_RS10965 2182771 2183043 - transcriptional regulator DNA-binding%3B binds the RcnA promotor gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10965 SG48_RS10970 SG48_2157 SG48_RS10970 2183164 2183988 + nickel/cobalt efflux system RcnA membrane protein conferring nickel and cobalt resistance gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10970 SG48_RS10975 SG48_2158 SG48_RS10975 2184207 2184545 + nickel/cobalt homeostasis protein RcnB gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10975 SG48_RS10980 SG48_2159 SG48_RS10980 2184627 2185661 - fimbrial-like adhesin protein gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10980 SG48_RS10985 SG48_2160 SG48_RS10985 2185677 2188157 - outer membrane usher protein YehB gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10985 SG48_RS10990 SG48_2161 SG48_RS10990 2188173 2188847 - fimbrial assembly chaperone protein StcB gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10990 SG48_RS10995 SG48_2162 SG48_RS10995 2188927 2189469 - fimbrial-like adhesin protein gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS10995 SG48_RS11000 SG48_RS11000 SG48_RS11000 2189658 2189838 + hypothetical protein gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11000 SG48_RS11005 SG48_2163 SG48_RS11005 2189762 2190043 - DUF2574 domain-containing protein gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11005 SG48_RS11010 SG48_2164 SG48_RS11010 2190306 2191415 - protein mrp gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11010 SG48_RS11015 SG48_2165 metG metG 2191547 2193580 + methionine--tRNA ligase methionine--tRNA ligase%3B MetRS%3B adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate%3B some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not%3B four subfamilies exist based on sequence motifs and zinc content gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11015 SG48_RS11020 SG48_RS11020 SG48_RS11020 2193721 2194545 + molybdenum metabolism regulator gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11020 SG48_RS11025 SG48_RS11025 SG48_RS11025 2196157 2197516 + regulator gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11025 SG48_RS11030 SG48_2167 SG48_RS11030 2197526 2201158 + DUF4132 domain-containing protein gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11030 SG48_RS11035 SG48_2168 SG48_RS11035 2201219 2201536 + hypothetical protein gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11035 SG48_RS11040 SG48_2169 SG48_RS11040 2201843 2202931 + hexameric AAA+ MoxR family ATPase gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11040 SG48_RS11045 SG48_2170 SG48_RS11045 2202942 2205221 + hypothetical protein gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11045 SG48_RS11050 SG48_2171 SG48_RS11050 2205214 2206350 + VMA domain YehL ATPase stimulator gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11050 SG48_RS11055 SG48_RS11055 SG48_RS11055 2206347 2208191 + hypothetical protein gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11055 SG48_RS11060 SG48_2173 SG48_RS11060 2208472 2208933 + DUF1307 domain-containing protein gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11060 SG48_RS11065 SG48_2174 SG48_RS11065 2208973 2209443 - DUF1456 domain-containing protein gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11065 SG48_RS11070 SG48_2175 SG48_RS11070 2209490 2210209 - two-component system response regulator unknown function%3B when overproduced it confers drug-resistance gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11070 SG48_RS11075 SG48_2176 SG48_RS11075 2210206 2211891 - sensor histidine kinase gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11075 SG48_RS11080 SG48_2177 SG48_RS11080 2212113 2212844 + transcriptional regulator gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11080 SG48_RS11085 SG48_2178 SG48_RS11085 2212904 2213011 + membrane protein gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11085 SG48_RS11090 SG48_2179 SG48_RS11090 2212992 2213723 - ABC transporter permease gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11090 SG48_RS11095 SG48_2180 SG48_RS11095 2213728 2214654 - ABC transporter ATPase gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11095 SG48_RS11100 SG48_2181 SG48_RS11100 2214647 2215804 - ABC transporter permease gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11100 SG48_RS11105 SG48_2182 SG48_RS11105 2215811 2216728 - ABC transporter substrate-binding protein gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11105 SG48_RS11110 SG48_2183 SG48_RS11110 2216939 2219236 - periplasmic beta-glucosidase catalyzes the hydrolysis of terminal beta-D-glucosyl residues gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11110 SG48_RS11115 SG48_2184 SG48_RS11115 2219432 2221147 + lactate dehydrogenase component of the membrane-bound D-lactate oxidase%2C FAD-binding%2C NADH independent gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11115 SG48_RS11120 SG48_2185 pbpG pbpG 2221185 2222117 - D-alanyl-D-alanine endopeptidase specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi%3B Penicillin-binding protein 7 gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11120 SG48_RS11125 SG48_2186 SG48_RS11125 2222291 2222878 - hypothetical protein gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11125 SG48_RS11130 SG48_2187 SG48_RS11130 2223048 2223626 + hypothetical protein gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11130 SG48_RS11135 SG48_2188 SG48_RS11135 2223756 2224517 - oxidoreductase gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11135 SG48_RS11140 SG48_RS11140 SG48_RS11140 2224570 2226005 - multidrug transporter permease may be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11140 SG48_RS11145 SG48_2190 SG48_RS11145 2226229 2226312 + hypothetical protein gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11145 SG48_RS11150 SG48_2191 SG48_RS11150 2226685 2227632 - tRNA-dihydrouridine synthase C gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11150 SG48_RS11155 SG48_2192 SG48_RS11155 2227871 2228269 + hypothetical protein gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11155 SG48_RS11160 SG48_2193 SG48_RS11160 2228266 2228961 + hypothetical protein gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11160 SG48_RS11165 SG48_2194 SG48_RS11165 2229091 2229975 + cytidine deaminase Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11165 SG48_RS11170 SG48_2195 SG48_RS11170 2230125 2230844 + protein SanA involved in vancomycin sensitivity and other barrier functions of the cell envelope gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11170 SG48_RS11175 SG48_2196 SG48_RS11175 2230847 2231086 + DUF2542 domain-containing protein gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11175 SG48_RS11180 SG48_2197 SG48_RS11180 2231280 2232518 + NAD-dependent dihydropyrimidine dehydrogenase subunit PreT gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11180 SG48_RS11185 SG48_2198 SG48_RS11185 2232512 2233747 + NAD-dependent dihydropyrimidine dehydrogenase subunit PreA gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11185 SG48_RS11190 SG48_2199 mglC mglC 2233990 2235000 - galactoside ABC transporter permease ABC transporter%3B functions in galactose transport%3B part of MglA2C2B transporter complex gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11190 SG48_RS11195 SG48_2200 SG48_RS11195 2235016 2236536 - galactose/methyl galactoside import ATP-binding protein MglA gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11195 SG48_RS11200 SG48_2201 SG48_RS11200 2236597 2237595 - D-galactose-binding periplasmic protein wtih MglAC is involved in the transport of beta-methylgalactoside gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11200 SG48_RS11205 SG48_2202 SG48_RS11205 2237875 2238915 - transcriptional regulator controls transcription of galETKM gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11205 SG48_RS11210 SG48_RS11210 SG48_RS11210 2238905 2239108 + hypothetical protein gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11210 SG48_RS11215 SG48_2203 SG48_RS11215 2239057 2240214 - DUF418 domain-containing protein gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11215 SG48_RS11220 SG48_2204 folE folE 2240231 2240899 - GTP cyclohydrolase 1 involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11220 SG48_RS11225 SG48_RS11225 SG48_RS11225 2241053 2241229 + hypothetical protein gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11225 SG48_RS11230 SG48_2205 SG48_RS11230 2241157 2241993 + S-formylglutathione hydrolase YeiG gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11230 SG48_RS11235 SG48_2206 SG48_RS11235 2242025 2244016 - colicin I receptor Cir%3B FeuA%3B CirA%3B receptor protein for siderophores (colicin IA%2C IB and V) and microcins (E492%2C H47%2C and M)%3B TonB-dependent%3B able to transport monomers%2C dimer%2C and linear trimers of 2%2C3-dihydorxybenzoylserine%3B outer membrane protein gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11235 SG48_RS11240 SG48_2207 SG48_RS11240 2244310 2245779 - lysine-specific permease gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11240 SG48_RS11245 SG48_2208 SG48_RS11245 2245984 2246865 - transcriptional regulator gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11245 SG48_RS11250 SG48_2209 SG48_RS11250 2246964 2248013 + hypothetical protein gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11250 SG48_RS11255 SG48_2210 SG48_RS11255 2248087 2248944 + endonuclease IV with intrinsic 3''-5'' exonuclease activity Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11255 SG48_RS11260 SG48_2211 SG48_RS11260 2248947 2250035 + kinase gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11260 SG48_RS11265 SG48_2212 SG48_RS11265 2250142 2251392 - nucleoside permease NupX gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11265 SG48_RS11270 SG48_2213 rihB rihB 2251492 2252433 - pyrimidine-specific ribonucleoside hydrolase RihB Hydrolyzes cytidine or uridine to ribose and cytosine or uracil%2C respectively gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11270 SG48_RS11275 SG48_2214 SG48_RS11275 2252563 2253261 + Crp/Fnr family transcriptional regulator activator of nucleoside metabolism gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11275 SG48_RS11280 SG48_2215 SG48_RS11280 2253332 2254582 - nucleoside transporter gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11280 SG48_RS11285 SG48_2216 SG48_RS11285 2254676 2255614 - pseudouridine-5'-phosphate glycosidase gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11285 SG48_RS11290 SG48_2217 SG48_RS11290 2255602 2256543 - pseudouridine kinase gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11290 SG48_RS11295 SG48_2218 SG48_RS11295 2256966 2258657 - PTS fructose EIIBC component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11295 SG48_RS11300 SG48_2219 fruK fruK 2258674 2259612 - 1-phosphofructokinase converts fructose-1-phosphate and ATP to fructose-1%2C6-bisphosphate and ADP%3B highly specific for fructose-1-phopshate%3B similar to PfkB%3B forms homodimers gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11300 SG48_RS11305 SG48_2220 SG48_RS11305 2259612 2260742 - multiphosphoryl transfer protein phosphoenolpyruvate (PEP)-dependent%2C sugar transporting phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIA is phosphorylated by phospho-HPr which then transfers the phosphoryl group to the IIB component gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11305 SG48_RS11310 SG48_2221 SG48_RS11310 2261110 2262291 + sugar efflux transporter B gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11310 SG48_RS11315 SG48_2222 SG48_RS11315 2262288 2262542 - hypothetical protein gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11315 SG48_RS11320 SG48_2223 SG48_RS11320 2262697 2263269 + elongation factor P-like protein Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro%2C suggesting its involvement in the formation of the first peptide bond of a protein gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11320 SG48_RS11325 SG48_2224 SG48_RS11325 2263492 2264958 + NAD-dependent D-mannonate oxidoreductase gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11325 SG48_RS11330 SG48_2225 SG48_RS11330 2265076 2266062 + GTPase gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11330 SG48_RS11335 SG48_2226 SG48_RS11335 2266101 2266814 + lipid A 1-diphosphate synthase gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11335 SG48_RS11340 SG48_2227 spr spr 2267226 2267792 + murein DD-endopeptidase MepS/Murein LD-carboxypeptidase mutational suppressor of prc thermosensitivity gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11340 SG48_RS11345 SG48_2228 SG48_RS11345 2267973 2269529 + protein Rtn involved in resistance to the phages N4 and lambda gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11345 SG48_RS11350 SG48_2229 SG48_RS11350 2269611 2271425 + microcin ABC transporter substrate-binding protein with YejBEF is involved in resistance to microcin C gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11350 SG48_RS11355 SG48_2230 SG48_RS11355 2271426 2272520 + ABC transporter permease with YejAEF is involved in resistance to microcin C gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11355 SG48_RS11360 SG48_2231 SG48_RS11360 2272520 2273545 + ABC transporter permease part of the microcin C transport system gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11360 SG48_RS11365 SG48_2232 SG48_RS11365 2273547 2275136 + microcin C ABC transporter ATPase with YejAEF is involved in resistance to microcin C gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11365 SG48_RS11370 SG48_2233 SG48_RS11370 2275140 2275484 - hypothetical protein gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11370 SG48_RS11375 SG48_2234 SG48_RS11375 2275817 2277007 - Bcr/CflA family drug resistance efflux transporter Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11375 SG48_RS11380 SG48_2235 SG48_RS11380 2277035 2277730 - ribosomal small subunit pseudouridine synthase A catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11380 SG48_RS11385 SG48_2236 SG48_RS11385 2277879 2279639 + ATP-dependent DNA or RNA helicase gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11385 SG48_RS11390 SG48_2237 SG48_RS11390 2279764 2280048 + 50S ribosomal protein L25 gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11390 SG48_RS11395 SG48_2238 SG48_RS11395 2280187 2281194 - nucleoid-associated protein gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11395 SG48_RS11400 SG48_2239 SG48_RS11400 2281376 2281603 + hypothetical protein gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11400 SG48_RS11405 SG48_2240 SG48_RS11405 2281623 2283383 + hypothetical protein gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11405 SG48_RS11410 SG48_2241 SG48_RS11410 2283458 2283527 + tRNA-OTHER tRNA gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11410 SG48_RS11415 SG48_RS11415 SG48_RS11415 2283630 2286140 - membrane protein gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11415 SG48_RS11420 SG48_2243 SG48_RS11420 2286305 2287285 - transposase gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11420 SG48_RS11425 SG48_RS11425 SG48_RS11425 2287451 2287708 - hypothetical protein gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11425 SG48_RS11430 SG48_2244 SG48_RS11430 2287740 2288387 + transcriptional regulator nitrate/nitrite response regulator NarP%3B NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems%3B represses expression of other anaerobic genes gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11430 SG48_RS11435 SG48_2245 SG48_RS11435 2288598 2289650 - cytochrome c-type biogenesis protein CcmH cytochrome c-type biogenesis protein%3B involved in the attachment of heme to cytochrome c gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11435 SG48_RS11440 SG48_2246 SG48_RS11440 2289647 2290204 - thiol:disulfide interchange protein DsbE cytochrome c-type biogenesis thioredoxin%3B involved in the reduction of disulfide bonds to allow heme bonding gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11440 SG48_RS11445 SG48_2247 SG48_RS11445 2290201 2292144 - cytochrome c-type biogenesis protein CcmF cytochrome c-type biogenesis protein%3B required for the transfer of heme to apocytochrome c gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11445 SG48_RS11450 SG48_2248 SG48_RS11450 2292141 2292620 - cytochrome c-type biogenesis protein CcmE CycJ%3B periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes%3B requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome%3B part of the cytochrome c maturation system%3B periplasmic protein anchored to the inner membrane gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11450 SG48_RS11455 SG48_2249 SG48_RS11455 2292617 2292826 - heme exporter protein D is invovled in heme transfer during cytochrome c biogenesis%3B acts to stabilize CcmC and CcmE gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11455 SG48_RS11460 SG48_2250 SG48_RS11460 2292823 2293560 - heme exporter protein C with CcmABDE is involved in the transport of protoheme IX%3B CcmC is required for heme transfer to CcmE gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11460 SG48_RS11465 SG48_2251 SG48_RS11465 2293602 2294261 - heme ABC transporter permease with CcmABCE is involved in the transport of protoheme IX%3B CcmB is required for the release of holoCcmE from CcmC gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11465 SG48_RS11470 SG48_2252 SG48_RS11470 2294261 2294878 - cytochrome C biogenesis protein CcmA gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11470 SG48_RS11475 SG48_2253 SG48_RS11475 2294897 2295499 - cytochrome c-type protein NapC with NapABDFGH functions as a nitrate reductase%3B NapC functions as an electron shuttle between NapAB and NapGH or quinone gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11475 SG48_RS11480 SG48_2254 napB napB 2295509 2295958 - periplasmic nitrate reductase electron transfer subunit small subunit of periplasmic nitrate reductase%3B receives electrons from the membrane-bound NapC and passes them to NapA gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11480 SG48_RS11485 SG48_2255 napH napH 2295955 2296818 - ferredoxin-type protein NapH part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11485 SG48_RS11490 SG48_2256 napG napG 2296805 2297500 - ferredoxin-type protein NapG part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA%3B secreted by twin arginine translocation pathway gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11490 SG48_RS11495 SG48_2257 SG48_RS11495 2297507 2299993 - periplasmic nitrate reductase periplasmic%3B catalytic subunit%3B with NapBC catalyzes the reduction of nitrate to nitrite%3B NapAB receives electrons from NapC gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11495 SG48_RS11500 SG48_2258 SG48_RS11500 2299990 2300253 - protein NapD gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11500 SG48_RS11505 SG48_2259 SG48_RS11505 2300243 2300737 - ferredoxin-type protein NapF Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA. gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11505 SG48_RS11510 SG48_RS11510 SG48_RS11510 2300846 2301010 + hypothetical protein gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11510 SG48_RS11515 SG48_2260 SG48_RS11515 2301145 2301633 + ecotin serine protease inhibitor%2C inhibits trypsin and other proteases gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11515 SG48_RS11520 SG48_2261 SG48_RS11520 2302348 2303994 - malate:quinone oxidoreductase gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11520 SG48_RS11525 SG48_2262 SG48_RS11525 2304212 2305855 - ABC transporter ATP-binding protein efflux pump for the antibacterial peptide microcin J25 gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11525 SG48_RS11530 SG48_2263 SG48_RS11530 2305931 2306581 - alpha-ketoglutarate-dependent dioxygenase AlkB gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11530 SG48_RS11535 SG48_2264 SG48_RS11535 2306581 2307645 - bifunctional transcriptional activator/DNA repair enzyme Ada regulates genes involved in the repair of alkylated DNA%3B repairs DNA containing 6-O-methylguanine gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11535 SG48_RS11540 SG48_2265 SG48_RS11540 2307719 2308774 - FAD--protein FMN transferase catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine%3B involved in the maintenance and/or assembly of sulfur clusters%3B periplasmic lipoporotein anchored to the inner membrane%3B part of the thiamine pyrophosphate biosynthesis pathway gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11540 SG48_RS11545 SG48_2266 SG48_RS11545 2308886 2309989 - outer membrane protein C gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11545 SG48_RS11550 SG48_RS11550 SG48_RS11550 2310248 2310340 - glutamate decarboxylase gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11550 SG48_RS11555 SG48_RS11555 SG48_RS11555 2310381 2310506 - hypothetical protein gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11555 SG48_RS11560 SG48_2268 SG48_RS11560 2310728 2313400 + phosphotransferase RcsD gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11560 SG48_RS11565 SG48_2269 SG48_RS11565 2313417 2314067 + transcriptional regulator two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division%3B probably phosphorylated by RcsC or RcsF gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11565 SG48_RS11570 SG48_2270 SG48_RS11570 2314267 2317116 - sensor histidine kinase gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11570 SG48_RS11575 SG48_2271 SG48_RS11575 2317283 2319109 + PAS domain-containing two-component system sensor histidine kinase with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11575 SG48_RS11580 SG48_2272 SG48_RS11580 2319106 2320491 + acetoacetate metabolism regulatory protein AtoC DNA-binding response regulator in two-component regulatory system with ZraS%3B response regulator/sigma54 interaction protein gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11580 SG48_RS11585 SG48_2273 SG48_RS11585 2320687 2321349 + acetate CoA-transferase subunit alpha gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11585 SG48_RS11590 SG48_2274 SG48_RS11590 2321349 2321999 + acetate CoA-transferase subunit beta gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11590 SG48_RS11595 SG48_2275 SG48_RS11595 2321996 2323318 + short-chain fatty acids transporter gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11595 SG48_RS11600 SG48_2276 SG48_RS11600 2323349 2324533 + acetyl-CoA acetyltransferase Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase%2C catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11600 SG48_RS11605 SG48_2277 SG48_RS11605 2324607 2325383 - hypothetical protein gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11605 SG48_RS11610 SG48_2278 SG48_RS11610 2325388 2327037 - host defense protein gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11610 SG48_RS11615 SG48_RS11615 SG48_RS11615 2327038 2327523 - alpha-2-macroglobulin gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11615 SG48_RS11620 SG48_RS11620 SG48_RS11620 2327539 2331552 - membrane protein gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11620 SG48_RS11625 SG48_2280 SG48_RS11625 2331576 2332199 - hypothetical protein gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11625 SG48_RS11630 SG48_2281 SG48_RS11630 2332196 2333884 - hypothetical protein gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11630 SG48_RS11635 SG48_2282 SG48_RS11635 2334033 2336660 - DNA gyrase subunit A gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11635 SG48_RS11640 SG48_2283 SG48_RS11640 2336807 2337529 + ubiquinone biosynthesis O-methyltransferase Involved in ubiquinone biosynthesis gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11640 SG48_RS11645 SG48_2284 SG48_RS11645 2337657 2341409 - adhesin gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11645 SG48_RS11650 SG48_RS11650 SG48_RS11650 2341881 2342024 + hypothetical protein gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11650 SG48_RS11655 SG48_2285 SG48_RS11655 2342105 2344390 + ribonucleoside-diphosphate reductase 1 subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11655 SG48_RS11660 SG48_2286 SG48_RS11660 2344624 2345754 + ribonucleoside-diphosphate reductase 1 subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11660 SG48_RS11665 SG48_2287 SG48_RS11665 2345754 2346008 + ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor%2C essential for nucleotide reduction catalyzed by ribonucleotide reductases gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11665 SG48_RS11670 SG48_2288 SG48_RS11670 2346062 2346712 - protein InaA gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11670 SG48_RS11675 SG48_RS11675 SG48_RS11675 2346927 2347133 + hypothetical protein gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11675 SG48_RS11680 SG48_2290 glpQ glpQ 2347175 2348251 - glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols%3B periplasmic gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11680 SG48_RS11685 SG48_2291 glpT glpT 2348256 2349614 - glycerol-3-phosphate transporter catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11685 SG48_RS11690 SG48_2292 glpA glpA 2349887 2351515 + anaerobic glycerol-3-phosphate dehydrogenase subunit A anaerobic%2C catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11690 SG48_RS11695 SG48_2293 SG48_RS11695 2351505 2352764 + anaerobic glycerol-3-phosphate dehydrogenase subunit B sn-glycerol-3-phosphate dehydrogenase (anaerobic)%3B catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate%3B part of GlpABC complex%3B presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11695 SG48_RS11700 SG48_2294 glpC glpC 2352761 2353951 + anaerobic glycerol-3-phosphate dehydrogenase subunit C anaerobic%3B with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11700 SG48_RS11705 SG48_2295 SG48_RS11705 2354144 2355043 + transposase gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11705 SG48_RS11710 SG48_RS11710 SG48_RS11710 2355056 2355241 + hypothetical protein gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11710 SG48_RS11715 SG48_2297 SG48_RS11715 2355282 2356085 - 2-keto-3-deoxy-L-rhamnonate aldolase catalyzes the retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate to pyruvate and lactaldehyde gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11715 SG48_RS11720 SG48_2298 SG48_RS11720 2356103 2357392 - transporter gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11720 SG48_RS11725 SG48_2299 SG48_RS11725 2357449 2358654 - L-rhamnonate dehydratase catalyzes the formation of 2-keto-3-deoxy-L-rhamnonate from L-rhamnonate gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11725 SG48_RS11730 SG48_2300 SG48_RS11730 2358669 2359451 - transcriptional regulator gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11730 SG48_RS11735 SG48_2301 SG48_RS11735 2359671 2360873 - inactive PncC family protein gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11735 SG48_RS11740 SG48_2302 SG48_RS11740 2360973 2361515 - porin gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11740 SG48_RS11745 SG48_2303 SG48_RS11745 2361794 2362219 + nucleoside triphosphatase catalyzes the hydrolysis of nucleoside triphosphates gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11745 SG48_RS11750 SG48_2304 SG48_RS11750 2362258 2362860 - LPS core heptose(II)-phosphate phosphatase catalyzes the of heptose(II) of the outer membrane lipopolysaccharide core gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11750 SG48_RS11755 SG48_2305 SG48_RS11755 2363168 2364307 + UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11755 SG48_RS11760 SG48_2306 SG48_RS11760 2364311 2365279 + undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11760 SG48_RS11765 SG48_2307 SG48_RS11765 2365279 2367261 + bifunctional polymyxin resistance protein ArnA Bifunctional polymyxin resistance arnA protein%3B catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose%3B active in certain mutant strains gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11765 SG48_RS11770 SG48_2308 SG48_RS11770 2367258 2368148 + 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD catalyzes the formation of 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11770 SG48_RS11775 SG48_2309 arnT arnT 2368148 2369800 + undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11775 SG48_RS11780 SG48_2310 SG48_RS11780 2369797 2370132 + 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE with ArnE is involved in transporting 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from the cytoplasmic face to the periplasmic face of the inner membrane gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11780 SG48_RS11785 SG48_2311 SG48_RS11785 2370132 2370518 + 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF with ArnE is responsible for the transport of 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from the cytoplasm to the periplasm gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11785 SG48_RS11790 SG48_2312 SG48_RS11790 2370512 2370778 - signal transduction protein PmrD with BasR regulates genes involved in polymyxin resistance gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11790 SG48_RS11795 SG48_2313 SG48_RS11795 2370888 2372243 - 2-succinylbenzoate--CoA ligase gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11795 SG48_RS11800 SG48_2314 SG48_RS11800 2372240 2373202 - o-succinylbenzoate synthase catalyzes the dehydration of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11800 SG48_RS11805 SG48_2315 SG48_RS11805 2373202 2374059 - 1%2C4-dihydroxy-2-naphthoyl-CoA synthase catalyzes the formation of 1%2C4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11805 SG48_RS11810 SG48_2316 SG48_RS11810 2374074 2374832 - 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase catalyzes the formation of (1 R%2C6 R)-2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11810 SG48_RS11815 SG48_2317 SG48_RS11815 2374829 2376499 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase SEPHCHC synthase%3B forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11815 SG48_RS11820 SG48_2318 SG48_RS11820 2376588 2377883 - isochorismate synthase MenF gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11820 SG48_RS11825 SG48_2319 SG48_RS11825 2377962 2378267 - protein ElaB gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11825 SG48_RS11830 SG48_2320 SG48_RS11830 2378322 2378783 - protein ElaA gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11830 SG48_RS11835 SG48_2321 SG48_RS11835 2378848 2379765 + hypothetical protein RNase BN%3B member of metallo-beta-lactamase family%3B the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase%3B in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not%3B associates with two zinc ions gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11835 SG48_RS11840 SG48_2322 SG48_RS11840 2379956 2381164 + deubiquitinase ElaD%3B specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins%3B SseL in Salmonella is required for macrophage killing and virulence%2C and it is secreted by the salmonella pathogenicity island 2 type III secretion system gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11840 SG48_RS11845 SG48_2323 SG48_RS11845 2381235 2382962 - VWA domain-containing protein gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11845 SG48_RS11850 SG48_2324 SG48_RS11850 2383100 2384071 + M28A family peptidase gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11850 SG48_RS11855 SG48_2325 SG48_RS11855 2384174 2384677 + hypothetical protein gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11855 SG48_RS11860 SG48_2326 SG48_RS11860 2384950 2385666 - hypothetical protein gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11860 SG48_RS11865 SG48_2327 SG48_RS11865 2385875 2386297 + hypothetical protein gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11865 SG48_RS11870 SG48_2328 SG48_RS11870 2386356 2387204 + hypothetical protein gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11870 SG48_RS11875 SG48_2329 SG48_RS11875 2387288 2388745 - NADH-quinone oxidoreductase subunit N Catalyzes the transfer of electrons from NADH to quinone gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11875 SG48_RS11880 SG48_2330 SG48_RS11880 2388752 2390281 - NADH-quinone oxidoreductase subunit M gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11880 SG48_RS11885 SG48_2331 SG48_RS11885 2390445 2392286 - NADH-quinone oxidoreductase subunit L Catalyzes the transfer of electrons from NADH to ubiquinone gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11885 SG48_RS11890 SG48_2332 SG48_RS11890 2392283 2392585 - NADH-quinone oxidoreductase subunit K gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11890 SG48_RS11895 SG48_2333 SG48_RS11895 2392582 2393136 - NADH-quinone oxidoreductase subunit J Catalyzes the transfer of electrons from NADH to quinone gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11895 SG48_RS11900 SG48_2334 SG48_RS11900 2393148 2393690 - NADH-quinone oxidoreductase subunit I gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11900 SG48_RS11905 SG48_2335 SG48_RS11905 2393705 2394682 - NADH-quinone oxidoreductase subunit H gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11905 SG48_RS11910 SG48_2336 SG48_RS11910 2394679 2397405 - NADH-quinone oxidoreductase subunit G Catalyzes the transfer of electrons from NADH to quinone gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11910 SG48_RS11915 SG48_2337 SG48_RS11915 2397458 2398795 - NADH-quinone oxidoreductase subunit F part of NADH-ubiquinone oxidoreductase complex I%3B shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B NuoF is part of the soluble NADH dehydrogenase fragment%2C which represents the electron input part of NADH dehydrogenase gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11915 SG48_RS11920 SG48_2338 SG48_RS11920 2398792 2399292 - NADH-quinone oxidoreductase subunit E Catalyzes the transfer of electrons from NADH to quinone gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11920 SG48_RS11925 SG48_2339 SG48_RS11925 2399295 2401085 - NADH-quinone oxidoreductase subunit C/D NuoCD%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B subunits NuoCD%2C E%2C F%2C and G constitute the peripheral sector of the complex%3B in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11925 SG48_RS11930 SG48_2340 SG48_RS11930 2401191 2401853 - NADH-quinone oxidoreductase subunit B gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11930 SG48_RS11935 SG48_2341 SG48_RS11935 2401869 2402312 - NADH-quinone oxidoreductase subunit A gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11935 SG48_RS11940 SG48_2342 SG48_RS11940 2402943 2403881 - transcriptional regulator involved in the regulation of genes involved in flagella synthesis%2C motility and chemotaxis gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11940 SG48_RS11945 SG48_2343 SG48_RS11945 2404801 2406018 + glutamate--pyruvate aminotransferase AlaA broad specificity%3B family IV%3B in Corynebacterium glutamicum this protein can use glutamate%2C 2-aminobutyrate%2C and aspartate as amino donors and pyruvate as the acceptor gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11945 SG48_RS11950 SG48_2344 SG48_RS11950 2406102 2406701 + 5'-deoxynucleotidase YfbR gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11950 SG48_RS11955 SG48_2345 SG48_RS11955 2406760 2408592 - transporter gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11955 SG48_RS11960 SG48_2346 SG48_RS11960 2408679 2409329 - sugar phosphatase YfbT gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11960 SG48_RS11965 SG48_2347 SG48_RS11965 2409340 2409834 - hypothetical protein gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11965 SG48_RS11970 SG48_2348 SG48_RS11970 2409917 2410372 - membrane protein gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11970 SG48_RS11975 SG48_RS11975 SG48_RS11975 2410441 2410572 - hypothetical protein gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11975 SG48_RS11980 SG48_2349 SG48_RS11980 2410710 2411912 + acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA%3B also known to act on propionate gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11980 SG48_RS11985 SG48_2350 SG48_RS11985 2411987 2414131 + phosphate acetyltransferase catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate%3B when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11985 SG48_RS11990 SG48_2351 SG48_RS11990 2414321 2415841 + inner membrane transporter%3B C4-dicarboxylate anaerobic carrier family protein gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11990 SG48_RS11995 SG48_2352 SG48_RS11995 2415874 2416416 - NUDIX hydrolase gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS11995 SG48_RS12000 SG48_2353 SG48_RS12000 2416474 2417025 - phosphodiesterase gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12000 SG48_RS12005 SG48_2354 SG48_RS12005 2417081 2417725 - glutathione S-transferase catalyzes the formation of 2%2C4-dinitrophenyl-S-glutathione from 1-chloro-2%2C4-dinitrobenzene and glutathione gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12005 SG48_RS12010 SG48_2355 SG48_RS12010 2417861 2418508 + disulfide-bond oxidoreductase YfcG gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12010 SG48_RS12015 SG48_2356 folX folX 2418565 2418927 + D-erythro-7%2C8-dihydroneopterin triphosphate epimerase catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12015 SG48_RS12020 SG48_2357 SG48_RS12020 2418948 2419841 + epimerase gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12020 SG48_RS12025 SG48_2358 SG48_RS12025 2419889 2420779 - transposase gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12025 SG48_RS12030 SG48_2359 SG48_RS12030 2420976 2421749 - histidine transport ATP-binding protein HisP gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12030 SG48_RS12035 SG48_2360 SG48_RS12035 2421757 2422473 - histidine ABC transporter permease with HisJPQ is involved in transport of histidine%2C lysine%2C arginine and ornithine gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12035 SG48_RS12040 SG48_2361 SG48_RS12040 2422470 2423156 - histidine ABC transporter permease with HisJMP is involved in the transport of histidine/lysine/arginine/ornithine gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12040 SG48_RS12045 SG48_2362 SG48_RS12045 2423246 2424028 - histidine-binding periplasmic protein with HisPMQ is involved in the transport of histidine gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12045 SG48_RS12050 SG48_2363 SG48_RS12050 2424249 2425031 - lysine/arginine/ornithine-binding periplasmic protein with HisPMQ is involved in the transport of histidine gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12050 SG48_RS12055 SG48_2364 SG48_RS12055 2425297 2425866 - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase partner protein catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12055 SG48_RS12060 SG48_2365 SG48_RS12060 2425961 2427478 - amidophosphoribosyltransferase Catalyzes first step of the de novo purine nucleotide biosynthetic pathway gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12060 SG48_RS12065 SG48_2366 SG48_RS12065 2427515 2428003 - colicin V production protein membrane protein required for colicin V production gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12065 SG48_RS12070 SG48_2367 SG48_RS12070 2428262 2428924 - protein DedD gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12070 SG48_RS12075 SG48_2368 SG48_RS12075 2428914 2430182 - bifunctional protein FolC gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12075 SG48_RS12080 SG48_2369 SG48_RS12080 2430252 2431166 - acetyl-CoA carboxylase carboxyltransferase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12080 SG48_RS12085 SG48_2370 SG48_RS12085 2431322 2431981 - protein DedA gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12085 SG48_RS12090 SG48_2371 truA truA 2432064 2432876 - tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12090 SG48_RS12095 SG48_2372 SG48_RS12095 2432876 2433889 - USG-1 protein gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12095 SG48_RS12100 SG48_2373 SG48_RS12100 2433955 2435091 - erythronate-4-phosphate dehydrogenase catalyzes the formation of 3-hydroxy-2-oxo-4-phosphonooxybutanoate from erythronate-4-phosphate gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12100 SG48_RS12105 SG48_2374 flk flk 2435190 2436185 + flagellar regulator flk in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system%3B lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm%3B inner membrane-anchored protein gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12105 SG48_RS12110 SG48_2375 SG48_RS12110 2436182 2437360 - arabinose efflux transporter gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12110 SG48_RS12115 SG48_2376 SG48_RS12115 2437625 2438845 - 3-oxoacyl-ACP synthase I FabB%2C beta-Ketoacyl-ACP synthase I%2C KASI%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12115 SG48_RS12120 SG48_2377 mnmC mnmC 2439004 2441010 + tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC 5-methylaminomethyl-2-thiouridine-forming enzyme methyltransferase/FAD-dependent demodification enzyme gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12120 SG48_RS12125 SG48_2378 SG48_RS12125 2441131 2441409 - hypothetical protein gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12125 SG48_RS12130 SG48_2379 SG48_RS12130 2441443 2441991 - elongation factor P hydroxylase gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12130 SG48_RS12135 SG48_2380 SG48_RS12135 2441991 2442800 - membrane protein gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12135 SG48_RS12140 SG48_2381 mepA mepA 2442800 2443624 - penicillin-insensitive murein endopeptidase D-alanyl-D-alanine endopeptidase%3B functions in hydrolyzing cell wall peptidoglycan%3B similar to LAS metallopeptidases%3B forms a dimer in periplasm gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12140 SG48_RS12145 SG48_2382 SG48_RS12145 2443628 2444713 - chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12145 SG48_RS12150 SG48_2383 SG48_RS12150 2444748 2445680 - 50S ribosomal protein L3 glutamine methyltransferase involved in methylation of ribosomal protein L3 gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12150 SG48_RS12155 SG48_2384 SG48_RS12155 2445846 2446397 + peptidase S10 gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12155 SG48_RS12160 SG48_2385 SG48_RS12160 2446468 2447289 - DUF2544 domain-containing protein gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12160 SG48_RS12165 SG48_2386 SG48_RS12165 2447291 2447830 - fimbrial-like adhesin protein gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12165 SG48_RS12170 SG48_2387 SG48_RS12170 2447827 2448315 - fimbrial-like adhesin protein gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12170 SG48_RS12175 SG48_2388 SG48_RS12175 2448312 2448809 - hypothetical protein gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12175 SG48_RS12180 SG48_2389 SG48_RS12180 2448824 2449576 - fimbrial chaperone gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12180 SG48_RS12185 SG48_RS12185 SG48_RS12185 2449596 2452241 - fimbrial assembly protein gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12185 SG48_RS12190 SG48_2391 SG48_RS12190 2452323 2452886 - fimbrial-like adhesin protein gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12190 SG48_RS12195 SG48_2392 SG48_RS12195 2453567 2454052 - phosphohistidine phosphatase gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12195 SG48_RS12200 SG48_2393 fadJ fadJ 2454255 2456399 - fatty acid oxidation complex subunit alpha multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI%3B similar to FadA2B2 complex%3B involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12200 SG48_RS12205 SG48_2394 fadI fadI 2456399 2457709 - 3-ketoacyl-CoA thiolase FadI%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadJ%3B similar to FadA2B2 complex%3B functions in beta-oxidation of fatty acids during anaerobic growth gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12205 SG48_RS12210 SG48_2395 SG48_RS12210 2457890 2458174 - hypothetical protein gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12210 SG48_RS12215 SG48_2396 SG48_RS12215 2458546 2459886 + long-chain fatty acid transporter gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12215 SG48_RS12220 SG48_2397 SG48_RS12220 2460252 2461310 + hypothetical protein gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12220 SG48_RS12225 SG48_2398 SG48_RS12225 2461492 2462247 - phospholipid-binding lipoprotein involved in maintaining OM lipid asymmetry gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12225 SG48_RS12230 SG48_2399 SG48_RS12230 2462541 2463473 + hypothetical protein gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12230 SG48_RS12235 SG48_2400 SG48_RS12235 2463549 2463623 + tRNA-Arg tRNA gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12235 SG48_RS12240 SG48_2401 SG48_RS12240 2463785 2464942 + hypothetical protein gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12240 SG48_RS12245 SG48_2402 SG48_RS12245 2465095 2465457 + glucose translocase gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12245 SG48_RS12250 SG48_2403 SG48_RS12250 2465454 2466374 + bactoprenol glucosyl transferase gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12250 SG48_RS12255 SG48_2404 SG48_RS12255 2466371 2467702 + serotype-specific glucosyl transferase CPS-53 (KpLE1) prophage gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12255 SG48_RS12260 SG48_RS12260 SG48_RS12260 2468001 2468345 + tail assembly protein gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12260 SG48_RS12265 SG48_2406 SG48_RS12265 2468317 2468757 - hypothetical protein gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12265 SG48_RS12270 SG48_RS12270 SG48_RS12270 2468784 2469419 - hypothetical protein gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12270 SG48_RS12275 SG48_RS12275 SG48_RS12275 2469352 2469627 - hypothetical protein gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12275 SG48_RS12280 SG48_2409 SG48_RS12280 2469627 2470115 - hypothetical protein gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12280 SG48_RS12285 SG48_RS12285 SG48_RS12285 2470118 2470486 - hypothetical protein gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12285 SG48_RS12290 SG48_2411 SG48_RS12290 2470844 2471206 + hypothetical protein gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12290 SG48_RS12295 SG48_2412 SG48_RS12295 2471272 2472096 + hypothetical protein gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12295 SG48_RS12300 SG48_2413 SG48_RS12300 2472224 2472760 + hypothetical protein gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12300 SG48_RS12305 SG48_2414 SG48_RS12305 2472751 2473113 + phage protein gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12305 SG48_RS12310 SG48_2415 SG48_RS12310 2473113 2473418 + hypothetical protein gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12310 SG48_RS12315 SG48_2417 SG48_RS12315 2473550 2473750 + transcriptional regulator gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12315 SG48_RS12320 SG48_2419 SG48_RS12320 2473934 2474869 - transcriptional regulator regulates the synthesis and expression of the dsdXA operon and dadA gene gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12320 SG48_RS12325 SG48_2420 SG48_RS12325 2475087 2476424 + dsdX permease gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12325 SG48_RS12330 SG48_2421 SG48_RS12330 2476442 2477770 + d-serine dehydratase catalyzes the formation of pyruvate from serine gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12330 SG48_RS12335 SG48_2422 emrB emrB 2477878 2479416 - multidrug resistance protein EmrY multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12335 SG48_RS12340 SG48_2423 SG48_RS12340 2479416 2480579 - multidrug resistance protein EmrK with ErmA and TolC forms a multidrug efflux system gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12340 SG48_RS12345 SG48_2424 SG48_RS12345 2480995 2481609 + positive transcription regulator EvgA response regulator in two-component regulatory system with EvgS%3B phosphorylated EvgA activates ompC%2C emrKY%2C gadABC%2C hdeAB and others genes%3B involved in acid resistance%2C osmotic adaption%2C and drug resistance gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12345 SG48_RS12350 SG48_2425 SG48_RS12350 2481824 2485207 + sensor histidine kinase gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12350 SG48_RS12355 SG48_2426 SG48_RS12355 2485263 2486408 - acetyl-CoA--oxalate CoA-transferase gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12355 SG48_RS12360 SG48_2427 SG48_RS12360 2486482 2487426 - transporter member of the AEC family of auxin efflux transporters%3B unknown function gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12360 SG48_RS12365 SG48_2428 SG48_RS12365 2487496 2489190 - oxalyl-CoA decarboxylase catalyzes the formation of formyl-CoA from oxalyl-CoA gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12365 SG48_RS12370 SG48_2429 SG48_RS12370 2489244 2490494 - formyl-CoA--oxalate CoA-transferase catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12370 SG48_RS12375 SG48_2430 SG48_RS12375 2491007 2491642 - hypothetical protein gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12375 SG48_RS12380 SG48_2431 SG48_RS12380 2491938 2492213 + lipoprotein involved in colanic acid biosynthesis gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12380 SG48_RS12385 SG48_RS12385 SG48_RS12385 2492198 2492335 - hypothetical protein gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12385 SG48_RS12390 SG48_2432 SG48_RS12390 2492290 2492532 - DUF2545 domain-containing protein gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12390 SG48_RS12395 SG48_2433 SG48_RS12395 2492885 2493805 + lipid A biosynthesis palmitoleoyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12395 SG48_RS12400 SG48_2435 SG48_RS12400 2494297 2495535 - glutamate--pyruvate aminotransferase AlaC gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12400 SG48_RS12405 SG48_2436 SG48_RS12405 2495911 2497608 + sensor histidine kinase gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12405 SG48_RS12410 SG48_2437 SG48_RS12410 2497623 2498357 + two-component system response regulator gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12410 SG48_RS12415 SG48_2438 SG48_RS12415 2498370 2499227 + DNA-binding protein gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12415 SG48_RS12420 SG48_2439 SG48_RS12420 2499230 2501725 - multiphosphoryl transfer protein 1 gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12420 SG48_RS12425 SG48_2440 SG48_RS12425 2501750 2502787 - aminopeptidase YpdE metalloprotein gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12425 SG48_RS12430 SG48_2441 SG48_RS12430 2502787 2503872 - aminopeptidase YpdF Xaa-Pro aminopeptidase%3B limited methionine aminopeptidase gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12430 SG48_RS12435 SG48_2442 SG48_RS12435 2503887 2505134 - Fructose-like permease IIC component 1 gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12435 SG48_RS12440 SG48_2443 SG48_RS12440 2505156 2505482 - fructose-like phosphotransferase enzyme IIB component 1 gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12440 SG48_RS12445 SG48_2444 glk glk 2505701 2506666 - glucokinase catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12445 SG48_RS12450 SG48_2445 SG48_RS12450 2506870 2508126 + ion channel protein gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12450 SG48_RS12455 SG48_2446 SG48_RS12455 2508241 2508567 + hypothetical protein gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12455 SG48_RS12460 SG48_RS12460 SG48_RS12460 2508488 2508649 + hypothetical protein gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12460 SG48_RS12465 SG48_2447 SG48_RS12465 2508708 2509946 - divalent metal cation transporter MntH gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12465 SG48_RS12470 SG48_2448 SG48_RS12470 2510282 2511484 + nucleoside permease NupC gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12470 SG48_RS12475 SG48_2449 SG48_RS12475 2511571 2512683 + transposase gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12475 SG48_RS12480 SG48_2450 SG48_RS12480 2512883 2515072 - diguanylate cyclase gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12480 SG48_RS12485 SG48_2451 SG48_RS12485 2515281 2515356 - tRNA-Ala tRNA gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12485 SG48_RS12490 SG48_2452 SG48_RS12490 2515396 2515471 - tRNA-Ala tRNA gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12490 SG48_RS12495 SG48_2453 SG48_RS12495 2515707 2516051 + DUF1323 family DNA-binding protein gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12495 SG48_RS12500 SG48_2454 SG48_RS12500 2516053 2516445 + DUF1323 family DNA-binding protein gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12500 SG48_RS12505 SG48_2455 gltX gltX 2516497 2517912 - glutamate--tRNA ligase catalyzes a two-step reaction%2C first charging an glutamate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12505 SG48_RS12510 SG48_2456 SG48_RS12510 2518171 2518246 + tRNA-Val tRNA gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12510 SG48_RS12515 SG48_2457 SG48_RS12515 2518291 2518366 + tRNA-Val tRNA gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12515 SG48_RS12520 SG48_2458 SG48_RS12520 2518413 2518488 + tRNA-Val tRNA gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12520 SG48_RS12525 SG48_2459 SG48_RS12525 2518493 2518568 + tRNA-Lys tRNA gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12525 SG48_RS12530 SG48_2460 SG48_RS12530 2518833 2519717 - transcriptional regulator gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12530 SG48_RS12535 SG48_RS12535 SG48_RS12535 2519758 2519916 - hypothetical protein gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12535 SG48_RS12540 SG48_2461 SG48_RS12540 2519969 2521225 - xanthosine permease gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12540 SG48_RS12545 SG48_2462 SG48_RS12545 2521285 2522118 - purine nucleoside phosphorylase gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12545 SG48_RS12550 SG48_2463 SG48_RS12550 2522367 2523131 + outer membrane protein gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12550 SG48_RS12555 SG48_2464 SG48_RS12555 2523170 2524096 - LysR family transcriptional regulator gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12555 SG48_RS12560 SG48_2465 SG48_RS12560 2524186 2525184 + inorganic ion transporter gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12560 SG48_RS12565 SG48_2466 SG48_RS12565 2525181 2525399 - DUF3820 domain-containing protein gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12565 SG48_RS12570 SG48_2467 ligA ligA 2525401 2527416 - DNA ligase this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12570 SG48_RS12575 SG48_2468 SG48_RS12575 2527487 2528473 - FtsZ stabilizer interacts with cell division protein FitsZ and may be required to anchor septal ring structure gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12575 SG48_RS12580 SG48_2469 SG48_RS12580 2528703 2529464 + sulfate transporter CysZ gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12580 SG48_RS12585 SG48_2470 SG48_RS12585 2529649 2530620 + cysteine synthase A gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12585 SG48_RS12590 SG48_2471 SG48_RS12590 2531004 2531261 + phosphocarrier protein HPr gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12590 SG48_RS12595 SG48_2472 SG48_RS12595 2531306 2533033 + phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12595 SG48_RS12600 SG48_2473 SG48_RS12600 2533074 2533583 + glucose-specific phosphotransferase enzyme IIA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12600 SG48_RS12605 SG48_2474 pdxK pdxK 2533626 2534477 - pyridoxine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12605 SG48_RS12610 SG48_2475 SG48_RS12610 2534582 2534956 + hypothetical protein gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12610 SG48_RS12615 SG48_2476 SG48_RS12615 2534989 2535723 + WGR domain protein gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12615 SG48_RS12620 SG48_2477 cysM cysM 2535912 2536823 - cysteine synthase B catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12620 SG48_RS12625 SG48_2478 SG48_RS12625 2536957 2538054 - sulfate/thiosulfate import ATP-binding protein CysA gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12625 SG48_RS12630 SG48_2479 cysW cysW 2538044 2538919 - sulfate ABC transporter permease Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12630 SG48_RS12635 SG48_2480 SG48_RS12635 2538919 2539752 - sulfate ABC transporter permease gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12635 SG48_RS12640 SG48_2481 SG48_RS12640 2539752 2540768 - thiosulfate-binding protein gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12640 SG48_RS12645 SG48_2482 SG48_RS12645 2541072 2541863 - oxidoreductase UcpA gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12645 SG48_RS12650 SG48_2483 SG48_RS12650 2541992 2542849 - transcriptional regulator repressor for murPQ%3B N-acetylmuramic acid 6-phosphate inducible gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12650 SG48_RS12655 SG48_2484 SG48_RS12655 2543013 2543909 + N-acetylmuramic acid 6-phosphate etherase catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate%3B involved in MurNAc dissimilation pathway gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12655 SG48_RS12660 SG48_2485 murP murP 2543913 2545337 + PTS N-acetylmuramic acid EIIBC component belongs to PEP-dependent PTS system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel%3B requires crr-encoded enzyme IIA-glucose component gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12660 SG48_RS12665 SG48_2486 SG48_RS12665 2545342 2546646 + penicillin-binding protein gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12665 SG48_RS12670 SG48_2487 SG48_RS12670 2546886 2547785 - deferrochelatase/peroxidase gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12670 SG48_RS12675 SG48_2488 SG48_RS12675 2547881 2548456 - RpoE-regulated lipoprotein gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12675 SG48_RS12680 SG48_2489 SG48_RS12680 2548517 2548966 - hypothetical protein gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12680 SG48_RS12685 SG48_2490 SG48_RS12685 2548953 2549378 - acetyltransferase YpeA gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12685 SG48_RS12690 SG48_2491 SG48_RS12690 2549592 2550461 + N-acetylmuramoyl-L-alanine amidase gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12690 SG48_RS12695 SG48_2492 SG48_RS12695 2550465 2551364 + coproporphyrinogen III oxidase catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12695 SG48_RS12700 SG48_2493 SG48_RS12700 2551370 2552422 - transcriptional regulator activates the transcription of the ethanolamine utilization operon gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12700 SG48_RS12705 SG48_2494 SG48_RS12705 2552468 2552968 - ethanolamine utilization protein EutK ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12705 SG48_RS12710 SG48_2495 SG48_RS12710 2552981 2553640 - ethanolamine utilization protein EutL carboxysome structural protein involved in ethanolamine utilization gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12710 SG48_RS12715 SG48_2496 SG48_RS12715 2553650 2554537 - ethanolamine ammonia-lyase light chain catalyzes the formation of acetaldehyde from ethanolamine gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12715 SG48_RS12720 SG48_2497 SG48_RS12720 2554558 2555919 - ethanolamine ammonia-lyase heavy chain with EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12720 SG48_RS12725 SG48_2498 SG48_RS12725 2556098 2557306 + hypothetical protein gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12725 SG48_RS12730 SG48_2499 SG48_RS12730 2557497 2558138 + hypothetical protein gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12730 SG48_RS12735 SG48_2500 SG48_RS12735 2558611 2558853 + hypothetical protein gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12735 SG48_RS12740 SG48_2501 SG48_RS12740 2558865 2559233 + hypothetical protein gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12740 SG48_RS12745 SG48_2502 SG48_RS12745 2559351 2559767 + hypothetical protein gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12745 SG48_RS12750 SG48_2503 SG48_RS12750 2559764 2560357 + hypothetical protein gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12750 SG48_RS12755 SG48_2504 SG48_RS12755 2560832 2561209 + hypothetical protein gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12755 SG48_RS12760 SG48_2505 SG48_RS12760 2561220 2561612 + hypothetical protein gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12760 SG48_RS12765 SG48_2506 SG48_RS12765 2561763 2562572 + hypothetical protein gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12765 SG48_RS12770 SG48_2507 eutA eutA 2562721 2564124 - ethanolamine utilization protein EutA ethanolamine utilization protein EutA gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12770 SG48_RS12775 SG48_2508 SG48_RS12775 2564121 2565347 - ethanolamine utilization protein EutH may be involved in the transport of ethanolamine gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12775 SG48_RS12780 SG48_2509 SG48_RS12780 2565564 2566751 - ethanolamine utilization protein EutG aldehyde reductase%3B catalyzes the conversion of acetaldehyde to ethanol gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12780 SG48_RS12785 SG48_2510 SG48_RS12785 2566741 2567577 - ethanolamine utilization protein EutJ possible chaperonin%3B may be involved in the assembly of the carboxysome gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12785 SG48_RS12790 SG48_2511 SG48_RS12790 2567588 2568991 - ethanolamine utilization protein EutE ethanolamine utilization protein%3B catalyzes the formation of acetyl-CoA from acetaldehyde gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12790 SG48_RS12795 SG48_2512 SG48_RS12795 2569003 2569290 - ethanolamine utilization protein EutN gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12795 SG48_RS12800 SG48_2513 SG48_RS12800 2569397 2569690 - ethanolamine utilization protein EutM ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12800 SG48_RS12805 SG48_2514 SG48_RS12805 2569729 2570745 - ethanolamine utilization protein EutD gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12805 SG48_RS12810 SG48_2515 SG48_RS12810 2570742 2571545 - ethanolamine utilization cobalamin adenosyltransferase catalyzes the conversion of cob(I)yrinic acid a%2Cc-diamide to adenosylcob(III)yrinic acid a%2Cc-diamide gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12810 SG48_RS12815 SG48_2516 SG48_RS12815 2571542 2572243 - ethanolamine utilization protein EutQ gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12815 SG48_RS12820 SG48_2517 SG48_RS12820 2572218 2572697 - ethanolamine utilization protein EutP gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12820 SG48_RS12825 SG48_2518 SG48_RS12825 2572710 2573045 - ethanolamine utilization protein EutS ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12825 SG48_RS12830 SG48_2519 SG48_RS12830 2573338 2575617 - NADP-dependent malic enzyme NADP-dependent%3B catalyzes the oxidative decarboxylation of malate to form pyruvate%3B decarboxylates oxaloacetate gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12830 SG48_RS12835 SG48_2520 SG48_RS12835 2575906 2576856 + transaldolase A gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12835 SG48_RS12840 SG48_2521 SG48_RS12840 2576876 2578879 + transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12840 SG48_RS12845 SG48_2522 SG48_RS12845 2578974 2580017 - DUF1176 domain-containing protein gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12845 SG48_RS12850 SG48_2523 SG48_RS12850 2580143 2580718 - GDP-mannose pyrophosphatase NudK gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12850 SG48_RS12855 SG48_2524 SG48_RS12855 2580786 2582765 - protein AegA unknown function%3B in E. coli the aegA gene is regulated by Fnr%2C NarXL%2C and NarQ (but not ArcA)%2C induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12855 SG48_RS12860 SG48_2525 SG48_RS12860 2582971 2584671 + nitrate/nitrite two-component system sensor histidine kinase gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12860 SG48_RS12865 SG48_2526 SG48_RS12865 2584835 2587948 + multidrug efflux RND transporter permease subunit gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12865 SG48_RS12870 SG48_RS12870 SG48_RS12870 2588035 2588214 + hypothetical protein gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12870 SG48_RS12875 SG48_2528 SG48_RS12875 2588487 2588843 + hypothetical protein gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12875 SG48_RS12880 SG48_2529 SG48_RS12880 2588847 2589974 + succinyl-diaminopimelate desuccinylase gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12880 SG48_RS12885 SG48_2530 SG48_RS12885 2590002 2590202 + membrane protein gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12885 SG48_RS12890 SG48_2531 SG48_RS12890 2590312 2591010 - esterase gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12890 SG48_RS12895 SG48_2532 SG48_RS12895 2591084 2593099 - tRNA(Met) cytidine acetyltransferase TmcA cetylates the wobble base C34 of the elongation-specific methionine tRNA gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12895 SG48_RS12900 SG48_2533 SG48_RS12900 2593114 2593977 - hypothetical protein gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12900 SG48_RS12905 SG48_2534 SG48_RS12905 2594145 2594858 - phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12905 SG48_RS12910 SG48_RS12910 SG48_RS12910 2594930 2595160 + hypothetical protein gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12910 SG48_RS12915 SG48_2535 SG48_RS12915 2595071 2596105 - outer membrane protein assembly factor BamC gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12915 SG48_RS12920 SG48_2536 SG48_RS12920 2596122 2597000 - 4-hydroxy-tetrahydrodipicolinate synthase gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12920 SG48_RS12925 SG48_2537 gcvR gcvR 2597146 2597718 + glycine cleavage system transcriptional regulator negative transcriptional regulator of the gcvTHP operon gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12925 SG48_RS12930 SG48_2538 bcp bcp 2597718 2598188 + peroxiredoxin bacterioferritin comigratory protein%3B thiol peroxidase%3B thioredoxin-dependent%3B hydroperoxide peroxidase%3B in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide%3B contains an active site cysteine gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12930 SG48_RS12935 SG48_2539 SG48_RS12935 2598441 2599058 + hydrogenase-4 component A gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12935 SG48_RS12940 SG48_2540 SG48_RS12940 2599058 2601076 + hydrogenase-4 component B gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12940 SG48_RS12945 SG48_2541 hycD hycD 2601087 2602034 + hydrogenase-4 component C formate hydrogenlyase subunit 4%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12945 SG48_RS12950 SG48_2542 SG48_RS12950 2602051 2603490 + hydrogenase-4 component D gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12950 SG48_RS12955 SG48_2543 hyfE hyfE 2603502 2604152 + hydrogenase-4 component E interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12955 SG48_RS12960 SG48_2544 SG48_RS12960 2604157 2605737 + hydrogenase-4 component F gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12960 SG48_RS12965 SG48_2545 SG48_RS12965 2605727 2607394 + hydrogenase-4 component G gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12965 SG48_RS12970 SG48_2546 SG48_RS12970 2607404 2607949 + hydrogenase-4 component H electron transfer protein for hydrogenase-3%3B the formate hydrogenlyase complex comprises of a formate dehydrogenase%2C unidentified electron carriers and hydrogenase-3%3B in this non-energy conserving pathway%2C molecular hydrogen and carbodioxide are released from formate gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12970 SG48_RS12975 SG48_2547 SG48_RS12975 2607946 2608704 + hydrogenase-4 component I gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12975 SG48_RS12980 SG48_2548 SG48_RS12980 2608697 2609110 + hydrogenase-4 component J gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12980 SG48_RS12985 SG48_2549 SG48_RS12985 2609140 2611152 + hydrogenase-4 transcriptional activator gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12985 SG48_RS12990 SG48_2550 SG48_RS12990 2611174 2612022 + formate transporter gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12990 SG48_RS12995 SG48_2551 SG48_RS12995 2612060 2613121 - permease gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS12995 SG48_RS13000 SG48_2552 SG48_RS13000 2613334 2614797 + beta-barrel assembly-enhancing protease gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13000 SG48_RS13005 SG48_2553 SG48_RS13005 2614818 2615177 + oxidoreductase gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13005 SG48_RS13010 SG48_2554 SG48_RS13010 2615315 2615992 - DnaA regulatory inactivator Hda controls initiation of DNA replication by inhibiting re-initiation of replication%2C promotes hydrolysis of DnaA-bound ATP gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13010 SG48_RS13015 SG48_2555 SG48_RS13015 2616111 2617400 - uracil permease gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13015 SG48_RS13020 SG48_2556 upp upp 2617486 2618112 - uracil phosphoribosyltransferase Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13020 SG48_RS13025 SG48_2557 SG48_RS13025 2618437 2619474 + phosphoribosylformylglycinamidine cyclo-ligase catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13025 SG48_RS13030 SG48_2558 purN purN 2619474 2620112 + phosphoribosylglycinamide formyltransferase glycinamide ribonucleotide transformylase%3B GAR Tfase%3B catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate%3B PurN requires formyl folate for the reaction unlike PurT which uses formate gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13030 SG48_RS13035 SG48_2559 SG48_RS13035 2620284 2622350 + polyphosphate kinase gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13035 SG48_RS13040 SG48_2560 SG48_RS13040 2622355 2623896 + exopolyphosphatase gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13040 SG48_RS13045 SG48_2561 SG48_RS13045 2623935 2626178 - cyclic di-GMP phosphodiesterase YfgF gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13045 SG48_RS13050 SG48_RS13050 SG48_RS13050 2626360 2626512 - hypothetical protein gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13050 SG48_RS13055 SG48_2562 SG48_RS13055 2626530 2626721 + hypothetical protein gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13055 SG48_RS13060 SG48_2563 SG48_RS13060 2627035 2627550 + membrane protein gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13060 SG48_RS13065 SG48_2564 SG48_RS13065 2627566 2628105 + nalidixic acid resistance protein gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13065 SG48_RS13070 SG48_2565 guaA guaA 2628198 2629775 - GMP synthase [glutamine-hydrolyzing] contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13070 SG48_RS13075 SG48_2566 SG48_RS13075 2629844 2631310 - inosine-5-monophosphate dehydrogenase gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13075 SG48_RS13080 SG48_2567 xseA xseA 2631472 2632842 + exodeoxyribonuclease 7 large subunit bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13080 SG48_RS13085 SG48_2568 SG48_RS13085 2632839 2633054 - DUF1407 domain-containing protein gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13085 SG48_RS13090 SG48_2569 SG48_RS13090 2633124 2634596 - GTPase Der gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13090 SG48_RS13095 SG48_2570 SG48_RS13095 2634714 2635892 - outer membrane protein assembly factor BamB gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13095 SG48_RS13100 SG48_2571 SG48_RS13100 2635903 2636523 - ancillary SecYEG translocon subunit gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13100 SG48_RS13105 SG48_2572 hisS hisS 2636541 2637815 - histidine--tRNA ligase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13105 SG48_RS13110 SG48_2573 SG48_RS13110 2637926 2639044 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13110 SG48_RS13115 SG48_2574 SG48_RS13115 2639071 2640084 - cytoskeleton protein RodZ gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13115 SG48_RS13120 SG48_2575 SG48_RS13120 2640369 2641523 - 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13120 SG48_RS13125 SG48_2576 SG48_RS13125 2641673 2642104 - nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13125 SG48_RS13130 SG48_2577 SG48_RS13130 2642253 2644565 - penicillin-binding protein 1C penicillin-insensitive transglycosylase/transpeptidase gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13130 SG48_RS13135 SG48_2578 SG48_RS13135 2644566 2649527 - hypothetical protein gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13135 SG48_RS13140 SG48_2579 sseA sseA 2649734 2650579 + 3-mercaptopyruvate sulfurtransferase catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13140 SG48_RS13145 SG48_2581 SG48_RS13145 2651397 2652173 - protein SseB enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13145 SG48_RS13150 SG48_2582 SG48_RS13150 2652315 2653598 - peptidase B catalyzes the removal of an N-terminal amino acid from a peptide or arylamide gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13150 SG48_RS13155 SG48_2583 SG48_RS13155 2653776 2653976 - protein IscX gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13155 SG48_RS13160 SG48_2584 SG48_RS13160 2653988 2654323 - (2Fe-2S) ferredoxin gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13160 SG48_RS13165 SG48_2585 hscA hscA 2654325 2656175 - chaperone protein HscA involved in the maturation of iron-sulfur cluster-containing proteins gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13165 SG48_RS13170 SG48_2586 hscB hscB 2656192 2656707 - co-chaperone protein HscB J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone%3B may function in biogenesis of iron-sulfur proteins gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13170 SG48_RS13175 SG48_2587 iscA iscA 2656803 2657126 - iron-binding protein forms iron-sulfur clusters of ferredoxin [2FE-2S]%3B binds iron in the presence of the thioredoxin reductase system%3B forms homodimers and tetramers%3B similar to SufA protein gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13175 SG48_RS13180 SG48_2588 SG48_RS13180 2657143 2657529 - Fe-S cluster assembly scaffold IscU gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13180 SG48_RS13185 SG48_2589 SG48_RS13185 2657557 2658771 - cysteine desulfurase IscS catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B involved in NAD biosynthesis gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13185 SG48_RS13190 SG48_2590 SG48_RS13190 2658883 2659371 - Fe-S cluster assembly transcriptional regulator IscR regulates the expression of the iscRSUA operon gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13190 SG48_RS13195 SG48_2591 SG48_RS13195 2659823 2660563 - tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ catalyzes the fromation of 2'O-methylated cytidine or 2'O-methylated uridine at position 32 in tRNA gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13195 SG48_RS13200 SG48_2592 SG48_RS13200 2660682 2661485 + inositol-1-monophosphatase gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13200 SG48_RS13205 SG48_2593 SG48_RS13205 2661630 2662484 + S9 family prolyl oligopeptidase gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13205 SG48_RS13210 SG48_2594 SG48_RS13210 2662675 2663955 + stationary phase-inducible protein CsiE gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13210 SG48_RS13215 SG48_2595 SG48_RS13215 2663947 2665086 - 3-phenylpropionic acid transporter transporter of 3-phenylpropionate across the inner membrane%3B member of the major facilitator superfamily of transporters gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13215 SG48_RS13220 SG48_2596 SG48_RS13220 2665246 2666136 - Hca operon transcriptional activator HcaR activator of 3-phenylpropionic acid catabolism gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13220 SG48_RS13225 SG48_2597 SG48_RS13225 2666272 2667633 + 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13225 SG48_RS13230 SG48_2598 SG48_RS13230 2667630 2668148 + 3-phenylpropionate/cinnamic acid dioxygenase subunit beta gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13230 SG48_RS13235 SG48_2599 SG48_RS13235 2668148 2668468 + 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13235 SG48_RS13240 SG48_2600 SG48_RS13240 2668465 2669277 + 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase Converts cis-3-(3-carboxyethyl)-3%2C5-cyclohexadiene-1%2C2-diol (PP-dihydrodiol) into 3-(2%2C3-dihydroxylphenyl)propionate gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13240 SG48_RS13245 SG48_2601 SG48_RS13245 2669287 2670489 + 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD+ reductase component gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13245 SG48_RS13250 SG48_2602 SG48_RS13250 2670586 2671008 + hypothetical protein gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13250 SG48_RS13255 SG48_2603 SG48_RS13255 2671056 2671928 - mutarotase superfamily protein%2C YphB family gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13255 SG48_RS13260 SG48_2604 SG48_RS13260 2671940 2673001 - Zn-dependent NAD(P)-binding oxidoreductase gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13260 SG48_RS13265 SG48_2605 SG48_RS13265 2673067 2674065 - ABC transporter permease gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13265 SG48_RS13270 SG48_2606 SG48_RS13270 2674090 2675601 - sugar ABC transporter ATPase gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13270 SG48_RS13275 SG48_2607 SG48_RS13275 2675624 2676607 - ABC transporter substrate-binding protein gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13275 SG48_RS13280 SG48_2608 SG48_RS13280 2676704 2679985 - DUF4380 domain-containing protein gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13280 SG48_RS13285 SG48_2609 SG48_RS13285 2680103 2681296 + transcriptional regulator gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13285 SG48_RS13290 SG48_2610 SG48_RS13290 2681494 2682747 - serine hydroxymethyltransferase gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13290 SG48_RS13295 SG48_2611 SG48_RS13295 2683075 2684265 + flavohemoprotein flavohemoprotein%3B catalyzes the formation of nitrate from nitric oxide%3B can also catalyze the reduction of dihydropteridine gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13295 SG48_RS13300 SG48_2612 SG48_RS13300 2684310 2684648 - nitrogen regulatory protein P-II 1 indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13300 SG48_RS13305 SG48_2613 SG48_RS13305 2684709 2686043 - transcriptional regulator with GlrK is part of a two-component signal transduction system regulating glmY gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13305 SG48_RS13310 SG48_2614 SG48_RS13310 2686033 2686746 - quorum-sensing regulator protein G gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13310 SG48_RS13315 SG48_2615 SG48_RS13315 2686911 2688338 - two-component system sensor histidine kinase part of the GlrKR two-component signal transduction system involved in the regulation of glmY gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13315 SG48_RS13320 SG48_2617 SG48_RS13320 2688896 2692783 - phosphoribosylformylglycinamidine synthase catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13320 SG48_RS13325 SG48_2618 SG48_RS13325 2693041 2694597 + murein transglycosylase gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13325 SG48_RS13330 SG48_2619 SG48_RS13330 2694594 2695097 - tRNA-specific adenosine deaminase gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13330 SG48_RS13335 SG48_2620 SG48_RS13335 2695155 2695790 - phosphatidylglycerophosphatase C gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13335 SG48_RS13340 SG48_2621 SG48_RS13340 2695999 2696847 + transcriptional regulator gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13340 SG48_RS13345 SG48_2622 SG48_RS13345 2696903 2697163 + 4Fe-4S binding protein gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13345 SG48_RS13350 SG48_2623 SG48_RS13350 2697357 2697437 - small toxic protein ShoB gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13350 SG48_RS13355 SG48_RS13355 SG48_RS13355 2697434 2697586 - hypothetical protein gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13355 SG48_RS13360 SG48_RS13360 SG48_RS13360 2697623 2697751 + glutamate decarboxylase gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13360 SG48_RS13365 SG48_2625 acpS acpS 2697858 2698238 - holo-ACP synthase Catalyzes the formation of holo-ACP%2C which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13365 SG48_RS13370 SG48_2626 SG48_RS13370 2698238 2698969 - pyridoxine 5'-phosphate synthase involved in the de novo synthesis of pyridoxine (Vitamin B6) gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13370 SG48_RS13375 SG48_2627 recO recO 2698981 2699709 - DNA repair protein RecO involved in DNA repair and RecFOR pathway recombination%3B RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13375 SG48_RS13380 SG48_2628 SG48_RS13380 2699721 2700626 - GTPase Era gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13380 SG48_RS13385 SG48_2629 rnc rnc 2700623 2701303 - ribonuclease 3 cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13385 SG48_RS13390 SG48_2630 SG48_RS13390 2701575 2702549 - signal peptidase I catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13390 SG48_RS13395 SG48_2631 SG48_RS13395 2702565 2704364 - elongation factor 4 gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13395 SG48_RS13400 SG48_2632 SG48_RS13400 2704562 2705041 - protein RseC involved in the reduction of the SoxR iron-sulfur cluster gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13400 SG48_RS13405 SG48_2633 rseB rseB 2705038 2705994 - sigma-E factor regulatory protein RseB periplasmic protein%3B interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13405 SG48_RS13410 SG48_2634 SG48_RS13410 2705994 2706644 - anti-sigma-E factor RseA gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13410 SG48_RS13415 SG48_2635 SG48_RS13415 2706677 2707252 - ECF RNA polymerase sigma-E factor Member of the extracytoplasmic function sigma factors which are active under specific conditions%3B binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription%3B this sigma factor is involved in heat shock and oxidative stress response gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13415 SG48_RS13420 SG48_RS13420 SG48_RS13420 2707249 2707404 - hypothetical protein gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13420 SG48_RS13425 SG48_2636 SG48_RS13425 2707660 2709282 + L-aspartate oxidase catalyzes the formation of oxaloacetate from L-aspartate gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13425 SG48_RS13430 SG48_2637 SG48_RS13430 2709267 2710004 - tRNA1(Val) (adenine(37)-N6)-methyltransferase gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13430 SG48_RS13435 SG48_2638 SG48_RS13435 2710136 2711470 + ATP-dependent RNA helicase SrmB facilitates an early step in the assembly of the 50S subunit of the ribosome gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13435 SG48_RS13440 SG48_RS13440 SG48_RS13440 2711476 2711628 + hypothetical protein gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13440 SG48_RS13445 SG48_2639 SG48_RS13445 2711679 2712560 - transcriptional regulator gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13445 SG48_RS13450 SG48_2640 SG48_RS13450 2712663 2713250 + cysteine/O-acetylserine efflux protein gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13450 SG48_RS13455 SG48_2641 SG48_RS13455 2713306 2713689 - autonomous glycyl radical cofactor GrcA stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13455 SG48_RS13460 SG48_2642 SG48_RS13460 2713994 2714683 + uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13460 SG48_RS13465 SG48_2643 SG48_RS13465 2714731 2715768 - methyltransferase gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13465 SG48_RS13470 SG48_RS13470 SG48_RS13470 2715758 2715916 - hypothetical protein gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13470 SG48_RS13475 SG48_2644 SG48_RS13475 2715975 2716394 + thioredoxin gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13475 SG48_RS13480 SG48_2645 SG48_RS13480 2716463 2717161 + DTW domain-containing protein YfiP gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13480 SG48_RS13485 SG48_2646 SG48_RS13485 2717193 2719853 + protein lysine acetyltransferase Pka catalyzes the acetylation of lysine gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13485 SG48_RS13490 SG48_2647 pssA pssA 2719967 2721322 + CDP-diacylglycerol--serine O-phosphatidyltransferase catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine%3B bounds to the ribosome gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13490 SG48_RS13495 SG48_2648 SG48_RS13495 2721419 2721691 + lipoprotein gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13495 SG48_RS13500 SG48_2649 SG48_RS13500 2721688 2722986 - alpha-ketoglutarate permease gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13500 SG48_RS13505 SG48_RS13505 SG48_RS13505 2723102 2723302 - hypothetical protein gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13505 SG48_RS13510 SG48_2650 SG48_RS13510 2723311 2723426 - 5S ribosomal RNA rRNA gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13510 SG48_RS13515 SG48_2651 SG48_RS13515 2723504 2726433 - 23S ribosomal RNA rRNA gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13515 SG48_RS13520 SG48_2652 SG48_RS13520 2726609 2726684 - tRNA-Glu tRNA gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13520 SG48_RS13525 SG48_2653 SG48_RS13525 2726844 2728399 - 16S ribosomal RNA rRNA gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13525 SG48_RS13530 SG48_2654 SG48_RS13530 2728840 2731413 - chaperone protein ClpB gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13530 SG48_RS13535 SG48_2656 SG48_RS13535 2731543 2732274 - Laccase YfiH gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13535 SG48_RS13540 SG48_2657 rluD rluD 2732271 2733251 - ribosomal large subunit pseudouridine synthase D responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13540 SG48_RS13545 SG48_2658 SG48_RS13545 2733386 2734123 + outer membrane protein assembly factor BamD gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13545 SG48_RS13550 SG48_RS13550 SG48_RS13550 2734153 2734359 + hypothetical protein gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13550 SG48_RS13555 SG48_2659 SG48_RS13555 2734394 2734735 + ribosome-associated inhibitor A associated with 30S ribosomal subunit%3B interferes with translation elongation gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13555 SG48_RS13560 SG48_2661 pheA pheA 2734985 2736145 + P-protein catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13560 SG48_RS13565 SG48_2662 tyrA tyrA 2736188 2737309 - T-protein catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13565 SG48_RS13570 SG48_2663 SG48_RS13570 2737320 2738390 - phospho-2-dehydro-3-deoxyheptonate aldolase Tyr-sensitive catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C tyrosine sensitive gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13570 SG48_RS13575 SG48_2664 SG48_RS13575 2738600 2738965 + lipoprotein gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13575 SG48_RS13580 SG48_2665 SG48_RS13580 2739115 2739633 + hypothetical protein gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13580 SG48_RS13585 SG48_2666 SG48_RS13585 2739626 2740849 + diguanylate cyclase gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13585 SG48_RS13590 SG48_2667 SG48_RS13590 2740865 2741347 + OM lipoprotein positive effector of YfiN activity gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13590 SG48_RS13595 SG48_2668 SG48_RS13595 2741423 2741770 - 50S ribosomal protein L19 gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13595 SG48_RS13600 SG48_2669 trmD trmD 2741812 2742579 - tRNA (guanine-N(1)-)-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13600 SG48_RS13605 SG48_2670 rimM rimM 2742610 2743158 - ribosome maturation factor RimM Essential for efficient processing of 16S rRNA gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13605 SG48_RS13610 SG48_2671 SG48_RS13610 2743177 2743425 - 30S ribosomal protein S16 gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13610 SG48_RS13615 SG48_2672 SG48_RS13615 2743674 2745035 - signal recognition particle protein gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13615 SG48_RS13620 SG48_2673 SG48_RS13620 2745202 2745993 + hypothetical protein gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13620 SG48_RS13625 SG48_2674 SG48_RS13625 2746059 2747300 + membrane protein gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13625 SG48_RS13630 SG48_2675 SG48_RS13630 2747355 2747948 - protein GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13630 SG48_RS13635 SG48_RS13635 SG48_RS13635 2747945 2748109 - heat-shock protein gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13635 SG48_RS13640 SG48_2676 ppnK ppnK 2748071 2748949 + NAD kinase catalyzes the phosphorylation of NAD to NADP gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13640 SG48_RS13645 SG48_2677 SG48_RS13645 2749035 2750696 + DNA repair protein RecN gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13645 SG48_RS13650 SG48_2678 SG48_RS13650 2750845 2751186 + outer membrane protein assembly factor BamE gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13650 SG48_RS13655 SG48_2679 SG48_RS13655 2751248 2751538 - hypothetical protein gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13655 SG48_RS13660 SG48_2680 SG48_RS13660 2751528 2752004 - ribosome association toxin RatA gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13660 SG48_RS13665 SG48_2681 smpB smpB 2752136 2752618 + SsrA-binding protein binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes%3B also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site%3B SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus%3B both the tmRNA and SmpB are regulated in cell cycle-dependent manner%3B functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13665 SG48_RS13670 SG48_2683 SG48_RS13670 2753399 2754640 + integrase gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13670 SG48_RS13675 SG48_2684 SG48_RS13675 2754884 2755759 - hypothetical protein gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13675 SG48_RS13680 SG48_2685 SG48_RS13680 2755884 2756096 + regulator AlpA gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13680 SG48_RS13685 SG48_2686 SG48_RS13685 2756225 2757634 + hypothetical protein gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13685 SG48_RS13690 SG48_2687 SG48_RS13690 2757787 2758413 + hypothetical protein gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13690 SG48_RS13695 SG48_2688 SG48_RS13695 2758591 2760780 - DEAD/DEAH box helicase gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13695 SG48_RS13700 SG48_2689 SG48_RS13700 2760777 2762393 - CP4-57 defective prophage%2C DUF4297/DUF1837 polymorphic toxin family protein gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13700 SG48_RS13705 SG48_2690 SG48_RS13705 2762753 2763016 - hypothetical protein gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13705 SG48_RS13710 SG48_2691 SG48_RS13710 2763158 2764231 + mRNA endoribonuclease LS gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13710 SG48_RS13715 SG48_2692 SG48_RS13715 2764224 2764595 + antitoxin RnlB gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13715 SG48_RS13720 SG48_2693 SG48_RS13720 2764950 2765813 + hypothetical protein gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13720 SG48_RS13725 SG48_2694 SG48_RS13725 2765905 2766726 + UPF0380 protein YfjQ gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13725 SG48_RS13730 SG48_2695 SG48_RS13730 2766943 2767644 + transcriptional regulator gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13730 SG48_RS13735 SG48_2696 SG48_RS13735 2767685 2767921 + hypothetical protein gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13735 SG48_RS13740 SG48_2697 SG48_RS13740 2767921 2768364 + hypothetical protein gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13740 SG48_RS13745 SG48_2698 SG48_RS13745 2768388 2768855 + periplasmic protein gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13745 SG48_RS13750 SG48_RS13750 SG48_RS13750 2769080 2769394 - arsenate reductase gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13750 SG48_RS13755 SG48_RS13755 SG48_RS13755 2769407 2770422 - arsenic transporter gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13755 SG48_RS13760 SG48_2701 SG48_RS13760 2770558 2772261 + hypothetical protein gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13760 SG48_RS13765 SG48_2703 SG48_RS13765 2773159 2773617 + antirestriction protein gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13765 SG48_RS13770 SG48_2704 SG48_RS13770 2773626 2774108 + DNA repair protein gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13770 SG48_RS13775 SG48_2706 SG48_RS13775 2774355 2774672 + hypothetical protein gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13775 SG48_RS13780 SG48_2707 SG48_RS13780 2774693 2775022 + toxin YpjF gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13780 SG48_RS13785 SG48_RS13785 SG48_RS13785 2775386 2775598 - ATPase gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13785 SG48_RS13795 SG48_RS13795 SG48_RS13795 2780305 2780448 - DNA invertase gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13795 SG48_RS13800 SG48_RS13800 SG48_RS13800 2780878 2781669 - hypothetical protein gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13800 SG48_RS13805 SG48_RS13805 SG48_RS13805 2781769 2782251 - hypothetical protein gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13805 SG48_RS13815 SG48_2712 SG48_RS13815 2783002 2783077 - tRNA-Met tRNA gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13815 SG48_RS13820 SG48_RS13820 SG48_RS13820 2783988 2784674 + alpha-1%2C2-mannosidase gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13820 SG48_RS13825 SG48_RS13825 SG48_RS13825 2784687 2785478 + alpha-amylase gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13825 SG48_RS13830 SG48_RS13830 SG48_RS13830 2785617 2785889 + alpha-amylase gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13830 SG48_RS13835 SG48_2714 SG48_RS13835 2786225 2787202 + protein CsiD in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP%3B the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases%3B forms homotetramers in solution gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13835 SG48_RS13840 SG48_2715 SG48_RS13840 2787222 2788490 + L-2-hydroxyglutarate oxidase LhgO catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13840 SG48_RS13845 SG48_2716 gabD gabD 2788513 2789961 + succinate-semialdehyde dehydrogenase [NADP+] catalyzes the formation of succinate from succinate semialdehyde%3B NADP dependent gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13845 SG48_RS13850 SG48_2717 SG48_RS13850 2789975 2791255 + 4-aminobutyrate aminotransferase GabT gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13850 SG48_RS13855 SG48_2718 SG48_RS13855 2791493 2792893 + GABA permease gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13855 SG48_RS13860 SG48_2719 SG48_RS13860 2792914 2793576 + transcriptional regulator regulator of gab gene expression gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13860 SG48_RS13865 SG48_2720 SG48_RS13865 2793577 2794026 - peptidoglycan-binding protein LysM gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13865 SG48_RS13870 SG48_2721 SG48_RS13870 2794110 2794268 - hypothetical protein gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13870 SG48_RS13875 SG48_2722 SG48_RS13875 2794451 2794750 + transcriptional regulator gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13875 SG48_RS13880 SG48_2723 SG48_RS13880 2794760 2795284 + hypothetical protein gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13880 SG48_RS13885 SG48_2724 SG48_RS13885 2795331 2795735 - DNA-binding protein StpA gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13885 SG48_RS13890 SG48_2725 SG48_RS13890 2796404 2796853 + L-alanine exporter AlaE gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13890 SG48_RS13895 SG48_2726 SG48_RS13895 2796890 2797234 - hypothetical protein gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13895 SG48_RS13900 SG48_2727 SG48_RS13900 2797386 2797715 + DUF883 domain-containing protein gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13900 SG48_RS13905 SG48_2728 SG48_RS13905 2797963 2798208 + glutaredoxin gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13905 SG48_RS13910 SG48_2729 nrdI nrdI 2798205 2798615 + protein NrdI in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13910 SG48_RS13915 SG48_2730 SG48_RS13915 2798588 2800732 + ribonucleoside-diphosphate reductase 2 subunit alpha gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13915 SG48_RS13920 SG48_2731 SG48_RS13920 2800742 2801701 + ribonucleoside-diphosphate reductase 2 subunit beta B2 or R2 protein%3B type 1b enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdE gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13920 SG48_RS13925 SG48_2732 SG48_RS13925 2802055 2803257 + glycine/betaine ABC transporter ATP-binding protein with ProWX is involved in the high-affinity uptake of glycine betaine gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13925 SG48_RS13930 SG48_2733 SG48_RS13930 2803250 2804314 + glycine/betaine ABC transporter permease with ProVX is involved in the high-affinity uptake of glycine betaine gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13930 SG48_RS13935 SG48_2734 proX proX 2804372 2805364 + glycine/betaine ABC transporter substrate-binding protein with ProVW%2C part of the high-affinity transport system for the osmoprotectant glycine betaine gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13935 SG48_RS13940 SG48_RS13940 SG48_RS13940 2805556 2806733 + transporter gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13940 SG48_RS13945 SG48_2736 SG48_RS13945 2806857 2807594 + hypothetical protein gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13945 SG48_RS13950 SG48_2737 SG48_RS13950 2807584 2807919 + L-valine exporter%2C norvaline resistance protein gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13950 SG48_RS13955 SG48_2738 SG48_RS13955 2808010 2808540 + transcriptional regulator DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux%3B negative regulator of the multidrug operon emrAB gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13955 SG48_RS13960 SG48_2739 SG48_RS13960 2808667 2809839 + multidrug export protein EmrA with ErmA and TolC forms a multidrug efflux system gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13960 SG48_RS13965 SG48_2740 emrB emrB 2809856 2811394 + multidrug effux MFS transporter subunit EmrB multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13965 SG48_RS13970 SG48_2741 SG48_RS13970 2811458 2811973 - S-ribosylhomocysteine lyase catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13970 SG48_RS13975 SG48_2743 SG48_RS13975 2812123 2813679 - glutamate--cysteine ligase involved in the first step of glutathione biosynthesis gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13975 SG48_RS13980 SG48_2744 SG48_RS13980 2813752 2814180 - hypothetical protein gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13980 SG48_RS13985 SG48_2745 SG48_RS13985 2814177 2814743 - fructose-1-phosphate phosphatase YqaB YqaB%3B catalyzes the dephosphorylation of fructose 1-phosphate%2C 6-phosphogluconate and p-nitrophenyl phosphate (pNPP)%3B presents beta-phosphoglucomutase activity at a lower extent gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13985 SG48_RS13995 SG48_2746 SG48_RS13995 2815024 2815100 - tRNA-Arg tRNA gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS13995 SG48_RS14000 SG48_2747 SG48_RS14000 2815299 2815375 - tRNA-Arg tRNA gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14000 SG48_RS14005 SG48_2748 SG48_RS14005 2815438 2815514 - tRNA-Arg tRNA gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14005 SG48_RS14010 SG48_2749 SG48_RS14010 2815713 2815789 - tRNA-Arg tRNA gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14010 SG48_RS14015 SG48_2750 SG48_RS14015 2815793 2815885 - tRNA-Ser tRNA gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14015 SG48_RS14020 SG48_2751 SG48_RS14020 2816201 2816386 - pleiotropic regulatory protein for carbon source metabolism affects carbohydrate metabolism%3B has regulatory role in many processes gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14020 SG48_RS14025 SG48_2752 SG48_RS14025 2816621 2819251 - alanine--tRNA ligase gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14025 SG48_RS14030 SG48_RS14030 SG48_RS14030 2819189 2819338 + hypothetical protein gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14030 SG48_RS14035 SG48_2753 recX recX 2819379 2819879 - regulatory protein RecX binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14035 SG48_RS14040 SG48_2754 recA recA 2819948 2821009 - protein RecA catalyzes the hydrolysis of ATP in the presence of single-stranded DNA%2C the ATP-dependent uptake of single-stranded DNA by duplex DNA%2C and the ATP-dependent hybridization of homologous single-stranded DNAs gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14040 SG48_RS14045 SG48_2755 SG48_RS14045 2821089 2821586 - nicotinamide-nucleotide amidohydrolase PncC gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14045 SG48_RS14050 SG48_2756 SG48_RS14050 2821731 2822816 - murein transglycosylase membrane-bound lytic murein transglycosylase B%3B catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14050 SG48_RS14055 SG48_2757 srlA srlA 2823072 2823635 + glucitol/sorbitol permease IIC component catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14055 SG48_RS14060 SG48_2758 srlE srlE 2823632 2824591 + glucitol/sorbitol-specific phosphotransferase enzyme IIB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIB transfers the phosphoryl group to the substrate gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14060 SG48_RS14065 SG48_2759 SG48_RS14065 2824602 2824973 + glucitol/sorbitol-specific phosphotransferase enzyme IIA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14065 SG48_RS14070 SG48_2760 SG48_RS14070 2824977 2825756 + sorbitol-6-phosphate 2-dehydrogenase catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14070 SG48_RS14075 SG48_2761 SG48_RS14075 2825861 2826220 + glucitol operon activator protein regulator for glucitol utilization gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14075 SG48_RS14080 SG48_2762 srlR srlR 2826287 2827060 + glucitol operon repressor regulates genes involved in glucitol utilization gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14080 SG48_RS14085 SG48_2763 SG48_RS14085 2827053 2828018 + arabinose 5-phosphate isomerase GutQ gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14085 SG48_RS14090 SG48_2764 SG48_RS14090 2828015 2829529 - NorR family transcriptional regulator Required for the expression of anaerobic nitric oxide (NO) reductase%3B acts as a transcriptional activator for the norVW operon gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14090 SG48_RS14095 SG48_2765 SG48_RS14095 2829716 2831155 + anaerobic nitric oxide reductase flavorubredoxin detoxifies nitric oxide using NADH gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14095 SG48_RS14100 SG48_2766 SG48_RS14100 2831152 2832285 + nitric oxide reductase FlRd-NAD+ reductase gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14100 SG48_RS14105 SG48_2767 SG48_RS14105 2832413 2834665 - hydrogenase maturation protein HypF carbamoyltransferase%3B involved in the formation of the cyanate group of hydrogenase%3B catalyzes the formation of carbamoyladenylate from carbamoylphosphate and then transfers the carbamoyl group to HypE gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14105 SG48_RS14110 SG48_2768 SG48_RS14110 2834818 2835345 - electron transporter HydN involved in electron transport from formate to hydrogen gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14110 SG48_RS14115 SG48_2769 SG48_RS14115 2835494 2836504 - transcriptional regulator gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14115 SG48_RS14120 SG48_2770 SG48_RS14120 2836764 2838221 + PTS arbutin-%2C cellobiose-%2C and salicin EIIBC component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14120 SG48_RS14125 SG48_2771 SG48_RS14125 2838230 2839654 + 6-phospho-beta-glucosidase AscB gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14125 SG48_RS14130 SG48_2772 hycI hycI 2839813 2840283 - hydrogenase 3 maturation protease involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14130 SG48_RS14135 SG48_2773 SG48_RS14135 2840276 2840686 - formate hydrogenlyase maturation protein HycH required for the maturation of the formate hydrogenlyase complex gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14135 SG48_RS14140 SG48_2774 SG48_RS14140 2840683 2841450 - formate hydrogenlyase subunit 7 gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14140 SG48_RS14145 SG48_2775 SG48_RS14145 2841450 2841992 - formate hydrogenlyase subunit 6 electron transfer protein for hydrogenase-3%3B the formate hydrogenlyase complex comprises of a formate dehydrogenase%2C unidentified electron carriers and hydrogenase-3%3B in this non-energy conserving pathway%2C molecular hydrogen and carbodioxide are released from formate gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14145 SG48_RS14150 SG48_2776 hycE hycE 2842002 2843711 - formate hydrogenlyase subunit 5 formate hydrogenlyase subunit 5%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14150 SG48_RS14155 SG48_2777 hycD hycD 2843729 2844652 - formate hydrogenlyase subunit 4 formate hydrogenlyase subunit 4%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14155 SG48_RS14160 SG48_2778 SG48_RS14160 2844655 2846481 - formate hydrogenlyase subunit 3 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen%3B formate hydrogenlyase comprises of a formate dehydrogenase%2C unidentified electron carriers and a hydrogenase (subunit 3) gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14160 SG48_RS14165 SG48_2779 SG48_RS14165 2846478 2847089 - formate hydrogenlyase subunit 2 gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14165 SG48_RS14170 SG48_RS14170 SG48_RS14170 2846990 2847298 + hypothetical protein gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14170 SG48_RS14175 SG48_2780 SG48_RS14175 2847214 2847675 - formate hydrogenlyase regulatory protein HycA regulates several genes involved in the formate hydrogenlyase system%3B seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14175 SG48_RS14180 SG48_2781 hypA hypA 2847887 2848237 + protein HypA plays a role in hydrogenase nickel cofactor insertion gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14180 SG48_RS14185 SG48_2782 SG48_RS14185 2848241 2849113 + hydrogenase isoenzymes nickel incorporation protein HypB GTP hydrolase involved in nickel liganding into hydrogenases gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14185 SG48_RS14190 SG48_2783 SG48_RS14190 2849104 2849376 + hydrogenase assembly protein HypC HypC%3B accessory protein necessary for maturation of the hydrogenase isoforms 1%2C 2 and 3%3B forms a complex with HypD%2C HypE%2C and HypF proteins%2C which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14190 SG48_RS14195 SG48_2784 SG48_RS14195 2849376 2850497 + hydrogenase isoenzymes formation protein HypD necessary for the synthesis of all three hydrogenase isoenzymes gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14195 SG48_RS14200 SG48_2785 SG48_RS14200 2850494 2851504 + hydrogenase isoenzymes formation protein HypE hydrogenase isoenzymes formation protein%3B involved in the formation of the cyanate group of the large subunit of the hydrogenase%3B catalyzes the formation of thiocyanate from thiocarbamate gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14200 SG48_RS14205 SG48_2786 SG48_RS14205 2851578 2853656 + formate hydrogenlyase transcriptional activator regulates the expression of formate dehydrogenase H and hydrogenase-3 structural genes gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14205 SG48_RS14210 SG48_2787 SG48_RS14210 2853693 2854046 - hypothetical protein gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14210 SG48_RS14215 SG48_2788 SG48_RS14215 2854333 2856894 + DNA mismatch repair protein MutS This protein performs the mismatch recognition step during the DNA repair process gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14215 SG48_RS14220 SG48_2789 SG48_RS14220 2857000 2857656 + Serine/threonine-protein phosphatase 2 gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14220 SG48_RS14225 SG48_2790 SG48_RS14225 2857707 2858474 - DeoR family transcriptional regulator gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14225 SG48_RS14230 SG48_2791 SG48_RS14230 2858670 2859578 + dehydrogenase gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14230 SG48_RS14235 SG48_2792 SG48_RS14235 2859575 2860741 + DUF1537 domain-containing protein gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14235 SG48_RS14240 SG48_2793 SG48_RS14240 2860833 2861471 + class II aldolase gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14240 SG48_RS14245 SG48_2794 SG48_RS14245 2861476 2862252 + hydroxypyruvate isomerase gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14245 SG48_RS14250 SG48_2795 SG48_RS14250 2862341 2863705 + permease member of the Gnt family of gluconate transporters%3B not involved in gluconate transport%3B unknown function gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14250 SG48_RS14255 SG48_2796 SG48_RS14255 2863799 2864791 - RNA polymerase sigma factor RpoS sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor controls a regulon of genes required for protection against external stresses gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14255 SG48_RS14260 SG48_2797 nlpD nlpD 2864854 2865993 - murein hydrolase activator NlpD outer membrane lipoprotein involved in stationary-phase cell survival%3B similar to LppB virulence determinant from Haemophilus somnus gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14260 SG48_RS14265 SG48_2798 pcm pcm 2866133 2866759 - protein-L-isoaspartate O-methyltransferase catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14265 SG48_RS14270 SG48_2799 surE surE 2866753 2867514 - 5'/3'-nucleotidase SurE broad specificity 5'(3')-nucleotidase and polyphosphatase gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14270 SG48_RS14275 SG48_2800 truD truD 2867495 2868544 - tRNA pseudouridine synthase D catalyzes the modification of U13 in tRNA(Glu) gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14275 SG48_RS14280 SG48_2801 ispF ispF 2868541 2869020 - 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14280 SG48_RS14285 SG48_2802 SG48_RS14285 2869020 2869730 - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14285 SG48_RS14290 SG48_2803 ftsB ftsB 2869749 2870060 - cell division protein FtsB forms a complex with FtsL and FtsQ%3B colocalizes to the septal region of the dividing cell%3B membrane protein gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14290 SG48_RS14295 SG48_2804 SG48_RS14295 2870254 2870577 - hypothetical protein gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14295 SG48_RS14300 SG48_2805 SG48_RS14300 2870627 2871232 - adenylyl-sulfate kinase converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14300 SG48_RS14305 SG48_2806 cysN cysN 2871232 2872659 - sulfate adenylyltransferase subunit 1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step%3B forms a heterodimer with CysD%3B part of the GTP-binding elongation factor family CysN/NodQ gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14305 SG48_RS14310 SG48_2807 SG48_RS14310 2872661 2873569 - sulfate adenylyltransferase subunit 2 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14310 SG48_RS14315 SG48_2808 SG48_RS14315 2873821 2874858 + alkaline phosphatase isozyme conversion protein catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14315 SG48_RS14320 SG48_2809 SG48_RS14320 2875809 2876093 - CRISPR-associated endonuclease Cas2 gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14320 SG48_RS14325 SG48_2810 SG48_RS14325 2876095 2877012 - subtype I-E CRISPR-associated endonuclease Cas1 gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14325 SG48_RS14330 SG48_2811 SG48_RS14330 2877028 2877627 - CRISPR system Cascade subunit CasE gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14330 SG48_RS14335 SG48_2812 SG48_RS14335 2877614 2878288 - CRISPR system Cascade subunit CasD gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14335 SG48_RS14340 SG48_2813 SG48_RS14340 2878291 2879382 - CRISPR system Cascade subunit CasC gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14340 SG48_RS14345 SG48_2814 SG48_RS14345 2879395 2879877 - CRISPR system Cascade subunit CasB gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14345 SG48_RS14350 SG48_2815 SG48_RS14350 2879870 2881378 - CRISPR system Cascade subunit CasA CRISP RNA (crRNA) containing protein gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14350 SG48_RS14355 SG48_2816 SG48_RS14355 2881793 2884459 - CRISPR-associated endonuclease/helicase Cas3 required for the activity of the Cascade antiviral complex gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14355 SG48_RS14360 SG48_2818 SG48_RS14360 2884818 2885552 - phosphoadenosine phosphosulfate reductase catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14360 SG48_RS14365 SG48_2819 SG48_RS14365 2885627 2887339 - sulfite reductase subunit beta hemoprotein%3B NADPH dependent%3B with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14365 SG48_RS14370 SG48_2820 cysJ cysJ 2887339 2889138 - sulfite reductase subunit alpha catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate%3B a flavoprotein with flavin reductase activity gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14370 SG48_RS14375 SG48_2821 SG48_RS14375 2889457 2889819 + 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin synthase gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14375 SG48_RS14380 SG48_2822 SG48_RS14380 2889897 2891168 + electron transfer flavoprotein-quinone oxidoreductase gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14380 SG48_RS14385 SG48_2823 SG48_RS14385 2891159 2891419 + ferredoxin-like protein YgcO gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14385 SG48_RS14390 SG48_2824 SG48_RS14390 2891436 2892011 + hypothetical protein gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14390 SG48_RS14395 SG48_2825 SG48_RS14395 2892159 2893019 - flavoprotein gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14395 SG48_RS14400 SG48_2826 SG48_RS14400 2893016 2893795 - flavoprotein gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14400 SG48_RS14405 SG48_2827 SG48_RS14405 2893773 2895110 - metabolite transporter gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14405 SG48_RS14410 SG48_2828 SG48_RS14410 2895204 2896658 - FAD-linked oxidoreductase gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14410 SG48_RS14415 SG48_2829 SG48_RS14415 2896728 2897513 - SDR family oxidoreductase gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14415 SG48_RS14420 SG48_2830 SG48_RS14420 2897832 2899109 + hypothetical protein gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14420 SG48_RS14425 SG48_2831 SG48_RS14425 2899136 2900614 + kinase gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14425 SG48_RS14430 SG48_2832 SG48_RS14430 2901987 2902658 - 7-carboxy-7-deazaguanine synthase gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14430 SG48_RS14435 SG48_2833 SG48_RS14435 2902797 2902937 + membrane stress resistance protein gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14435 SG48_RS14440 SG48_2834 SG48_RS14440 2902951 2903823 + TPM domain protein phosphatase gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14440 SG48_RS14445 SG48_2835 eno eno 2903883 2905181 - enolase catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14445 SG48_RS14450 SG48_2836 pyrG pyrG 2905269 2906906 - CTP synthase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14450 SG48_RS14455 SG48_2837 mazG mazG 2907134 2907925 - nucleoside triphosphate pyrophosphohydrolase functions in degradation of stringent response intracellular messenger ppGpp%3B in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF%3B activity of MazG is inhibited by MazEF in vitro%3B ppGpp inhibits mazEF expression%3B MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation%3B MazG also interacts with the GTPase protein Era gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14455 SG48_RS14460 SG48_2838 SG48_RS14460 2907996 2908331 - mRNA interferase MazF ChpA%3B endoribonuclease%3B toxin of the MazF-MazE (ChpA-ChpR) toxin-antitoxin system gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14460 SG48_RS14465 SG48_2839 SG48_RS14465 2908331 2908579 - antitoxin MazE part of the MazF-MazE toxin-antitoxin system%3B conteracts MazF gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14465 SG48_RS14470 SG48_2840 relA relA 2908657 2910891 - GTP pyrophosphokinase (p)ppGpp synthetase%3B catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14470 SG48_RS14475 SG48_2841 rumA rumA 2910939 2912240 - 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA%3B binds an iron-sulfur cluster [4Fe-4S] gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14475 SG48_RS14480 SG48_2842 SG48_RS14480 2912297 2915053 + signal transduction histidine kinase part of the two-component regulatory system with UvrY%3B involved in the regulation of carbon metabolism via the csrA/csrB regulatory system gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14480 SG48_RS14485 SG48_2843 gudD gudD 2915285 2916625 - glucarate dehydratase catalyzes the formation of 5-keto-4-deoxy-D-glucarate from glucarate gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14485 SG48_RS14490 SG48_2844 SG48_RS14490 2916646 2917986 - glucarate dehydratase-related protein gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14490 SG48_RS14495 SG48_2845 SG48_RS14495 2917988 2919340 - glucarate transporter gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14495 SG48_RS14500 SG48_2846 SG48_RS14500 2919775 2920224 - flavodoxin An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14500 SG48_RS14505 SG48_2847 SG48_RS14505 2920242 2921024 - tRNA pseudouridine synthase C catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14505 SG48_RS14510 SG48_2848 SG48_RS14510 2921024 2921353 - DUF446 domain-containing protein gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14510 SG48_RS14515 SG48_RS14515 SG48_RS14515 2921600 2921725 - hypothetical protein gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14515 SG48_RS14520 SG48_2850 SG48_RS14520 2921975 2922520 - protein Syd SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14520 SG48_RS14525 SG48_2851 queF queF 2922588 2923436 + NADPH-dependent 7-cyano-7-deazaguanine reductase catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14525 SG48_RS14530 SG48_2852 SG48_RS14530 2923548 2924912 + LOG family protein YgdH gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14530 SG48_RS14535 SG48_2853 SG48_RS14535 2925469 2926758 + serine transporter gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14535 SG48_RS14540 SG48_2854 SG48_RS14540 2926816 2928183 + L-serine dehydratase 2 catalyzes the formation of pyruvate from serine gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14540 SG48_RS14545 SG48_2855 SG48_RS14545 2928295 2929050 + flap endonuclease Xni similar to flap endonuclease%3B FEN family%3B protein from E. coli does not have exonuclease activity gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14545 SG48_RS14550 SG48_2856 SG48_RS14550 2929105 2930253 - lactaldehyde reductase gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14550 SG48_RS14555 SG48_2857 SG48_RS14555 2930281 2930928 - L-fuculose phosphate aldolase catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14555 SG48_RS14560 SG48_2858 SG48_RS14560 2931475 2932791 + L-fucose-proton symporter gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14560 SG48_RS14565 SG48_2859 fucI fucI 2932824 2934599 + L-fucose isomerase catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14565 SG48_RS14570 SG48_2860 SG48_RS14570 2934708 2936126 + L-fuculokinase gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14570 SG48_RS14575 SG48_2861 SG48_RS14575 2936128 2936550 + L-fucose mutarotase gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14575 SG48_RS14580 SG48_2862 SG48_RS14580 2936608 2937339 + l-fucose operon activator regulates expression of genes involved in L-fucose utilization gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14580 SG48_RS14585 SG48_2863 SG48_RS14585 2937383 2938483 - ribosomal RNA large subunit methyltransferase M gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14585 SG48_RS14590 SG48_2864 SG48_RS14590 2938476 2938871 - hypothetical protein gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14590 SG48_RS14595 SG48_2865 SG48_RS14595 2938890 2939807 - glycine cleavage system transcriptional activator Glycine cleavage system transcriptional activator%3B activates the gcvTHP operon in the presence of glycine and represses the operon in its absence gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14595 SG48_RS14600 SG48_2867 SG48_RS14600 2940158 2940385 - DUF903 domain-containing protein gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14600 SG48_RS14605 SG48_2868 SG48_RS14605 2940577 2941782 + cysteine desulfurase CsdA gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14605 SG48_RS14610 SG48_2869 SG48_RS14610 2941782 2942225 + sulfur acceptor protein CsdE binds and activates CsdA%3B Fe-S protein gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14610 SG48_RS14615 SG48_2870 SG48_RS14615 2942276 2943082 - tRNA threonylcarbamoyladenosine dehydratase accepts sulfur from CsdA gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14615 SG48_RS14620 SG48_2871 mltA mltA 2943321 2944418 - murein transglycosylase membrane-bound%2C lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14620 SG48_RS14625 SG48_2872 SG48_RS14625 2944627 2944703 + tRNA-Met tRNA gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14625 SG48_RS14630 SG48_2873 SG48_RS14630 2944737 2944813 + tRNA-Met tRNA gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14630 SG48_RS14635 SG48_2874 SG48_RS14635 2944847 2944923 + tRNA-Met tRNA gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14635 SG48_RS14640 SG48_2875 amiC amiC 2944997 2946250 - N-acetylmuramoyl-L-alanine amidase hydrolyzes the bond between N-acetylmuramic acid and amino acid residues in peptidoglycan gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14640 SG48_RS14645 SG48_2876 SG48_RS14645 2946482 2947813 + amino-acid acetyltransferase catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14645 SG48_RS14650 SG48_2877 recD recD 2947875 2949701 - RecBCD enzyme subunit RecD helicase/nuclease%3B with RecBC catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14650 SG48_RS14655 SG48_2878 recB recB 2949701 2953243 - RecBCD enzyme subunit RecB helicase/nuclease%3B with RecCD catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14655 SG48_RS14660 SG48_2879 SG48_RS14660 2953236 2956124 - protease 3 degrades small peptides gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14660 SG48_RS14665 SG48_2880 recC recC 2956300 2959668 - RecBCD enzyme subunit RecC catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides%3B component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14665 SG48_RS14670 SG48_2881 SG48_RS14670 2959681 2960004 - prepilin peptidase-dependent protein C gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14670 SG48_RS14675 SG48_2882 SG48_RS14675 2959989 2960396 - DUF2509 domain-containing protein gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14675 SG48_RS14680 SG48_2883 SG48_RS14680 2960393 2960956 - prepilin peptidase-dependent protein B gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14680 SG48_RS14685 SG48_2884 SG48_RS14685 2960947 2961417 - prepilin peptidase-dependent protein A gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14685 SG48_RS14690 SG48_2885 SG48_RS14690 2961601 2962395 - thymidylate synthase gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14690 SG48_RS14695 SG48_2886 SG48_RS14695 2962402 2963277 - prolipoprotein diacylglyceryl transferase gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14695 SG48_RS14700 SG48_2887 SG48_RS14700 2963428 2965674 - phosphoenolpyruvate-protein phosphotransferase PtsP member of a second PTS chain involved in nitrogen metabolism%3B PtsP phosphorylates NPr gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14700 SG48_RS14705 SG48_2888 SG48_RS14705 2965687 2966217 - RNA pyrophosphohydrolase hydrolyzes diadenosine polyphosphate gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14705 SG48_RS14710 SG48_RS14710 SG48_RS14710 2966529 2966723 + hypothetical protein gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14710 SG48_RS14715 SG48_RS14715 SG48_RS14715 2966662 2966823 + hypothetical protein gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14715 SG48_RS14720 SG48_2889 SG48_RS14720 2966902 2967591 + DNA mismatch repair protein MutH MutH%3B Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14720 SG48_RS14725 SG48_2890 SG48_RS14725 2967660 2968373 + membrane protein gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14725 SG48_RS14730 SG48_2891 SG48_RS14730 2968511 2968729 + hypothetical protein gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14730 SG48_RS14735 SG48_2892 tas tas 2968837 2969877 + protein tas complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain%3B member of the aldo/keto reductase 2 family%3B crystal structure of purified Escherichia coli protein shows bound NADPH gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14735 SG48_RS14740 SG48_2893 SG48_RS14740 2969909 2971102 - lysophospholipid transporter LplT gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14740 SG48_RS14745 SG48_2894 SG48_RS14745 2971095 2973254 - bifunctional protein Aas Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14745 SG48_RS14750 SG48_2897 SG48_RS14750 2973839 2974870 + transcriptional regulator controls transcription of galETKM gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14750 SG48_RS14755 SG48_2898 SG48_RS14755 2974877 2976139 - diaminopimelate decarboxylase catalyzes the decarboxylation of diaminopimelate into lysine%3B pyridoxal phosphate(PLP)-binding gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14755 SG48_RS14760 SG48_2899 SG48_RS14760 2976261 2977196 + LysR family transcriptional regulator activates the transcription of the lysA gene encoding diaminopimelate decarboxylase gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14760 SG48_RS14765 SG48_2900 SG48_RS14765 2977183 2977875 - Asp/Glu_racemase gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14765 SG48_RS14770 SG48_2901 SG48_RS14770 2978004 2979422 - arabinose-proton symporter gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14770 SG48_RS14775 SG48_2902 SG48_RS14775 2979737 2980498 - 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14775 SG48_RS14780 SG48_2903 SG48_RS14780 2980528 2981364 - 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase%3B catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2%2C5-hexodiulosonate gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14780 SG48_RS14785 SG48_2904 SG48_RS14785 2981651 2982832 - acetyl-CoA acetyltransferase gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14785 SG48_RS14790 SG48_2905 SG48_RS14790 2983087 2984316 + transporter gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14790 SG48_RS14795 SG48_2906 SG48_RS14795 2984890 2985408 + LuxR family transcriptional regulator gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14795 SG48_RS14800 SG48_2907 SG48_RS14800 2985742 2986551 + transcriptional regulator gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14800 SG48_RS14805 SG48_2908 SG48_RS14805 2986544 2987026 + hypothetical protein gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14805 SG48_RS14810 SG48_2910 SG48_RS14810 2987175 2987600 - hypothetical protein gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14810 SG48_RS14815 SG48_RS14815 SG48_RS14815 2987794 2988283 + hypothetical protein gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14815 SG48_RS14820 SG48_2912 SG48_RS14820 2988508 2988999 + SycD-like chaperone family hypothetical protein gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14820 SG48_RS14825 SG48_2913 SG48_RS14825 2989334 2990710 + transcriptional regulator gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14825 SG48_RS14830 SG48_2914 SG48_RS14830 2990878 2991096 + hypothetical protein gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14830 SG48_RS14835 SG48_RS14835 SG48_RS14835 2991281 2991655 + lytic transglycosylase gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14835 SG48_RS14840 SG48_RS14840 SG48_RS14840 2991700 2992146 - LuxR family transcriptional regulator gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14840 SG48_RS14845 SG48_RS14845 SG48_RS14845 2992177 2992332 - transcriptional regulator gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14845 SG48_RS14850 SG48_RS14850 SG48_RS14850 2992554 2992985 - hypothetical protein gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14850 SG48_RS14855 SG48_RS14855 SG48_RS14855 2992988 2993260 - hypothetical protein gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14855 SG48_RS14860 SG48_RS14860 SG48_RS14860 2993202 2993357 - secretion protein gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14860 SG48_RS14865 SG48_2919 SG48_RS14865 2993612 2994517 - integrase gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14865 SG48_RS14870 SG48_2920 SG48_RS14870 2994475 2994840 - transposase represses IS2 gene transcription gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14870 SG48_RS14875 SG48_RS14875 SG48_RS14875 2994929 2995228 - hypothetical protein gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14875 SG48_RS14880 SG48_RS14880 SG48_RS14880 2995274 2996068 - hypothetical protein gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14880 SG48_RS14885 SG48_2922 SG48_RS14885 2996224 2996297 - tRNA-Gly tRNA gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14885 SG48_RS14890 SG48_2923 SG48_RS14890 2996376 2997131 - peptidoglycan-binding protein LysM gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14890 SG48_RS14895 SG48_2924 SG48_RS14895 2997546 2999843 + xanthine dehydrogenase subunit A molybdenum cofactor-binding protein%3B participates in purine salvage gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14895 SG48_RS14900 SG48_2925 SG48_RS14900 2999854 3000732 + xanthine dehydrogenase FAD-binding subunit FAD-binding subunit%3B with XdhA and XdhC participates in purine salvage gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14900 SG48_RS14905 SG48_2926 SG48_RS14905 3000729 3001208 + xanthine dehydrogenase iron-sulfur-binding subunit iron-sulfur-binding subunit%3B with XdhA and XdhB participates in purine salvage gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14905 SG48_RS14910 SG48_2927 SG48_RS14910 3001248 3003026 - sigma-54-interacting transcriptional activator gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14910 SG48_RS14915 SG48_2928 SG48_RS14915 3003505 3004692 + ornithine carbamoyltransferase gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14915 SG48_RS14920 SG48_2929 SG48_RS14920 3004750 3005946 + diaminopropionate ammonia-lyase catalyzes the formation of pyruvate from 2%2C3-diaminopropionate gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14920 SG48_RS14925 SG48_2930 SG48_RS14925 3006004 3007215 + peptidase Zn-dependent extracellular dipeptidase%3B similar to succinyl-diaminopimelate desuccinylases gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14925 SG48_RS14930 SG48_2931 SG48_RS14930 3007268 3008653 + D-phenylhydantoinase catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14930 SG48_RS14935 SG48_2932 SG48_RS14935 3008701 3009633 + carbamate kinase-like protein YqeA gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14935 SG48_RS14940 SG48_2933 SG48_RS14940 3009854 3011479 - XdhC-CoxI family protein with NAD(P)-binding Rossman fold gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14940 SG48_RS14945 SG48_2934 SG48_RS14945 3011527 3012297 - selenium-dependent hydroxylase accessory protein gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14945 SG48_RS14950 SG48_2935 SG48_RS14950 3012400 3012978 + molybdenum cofactor cytidylyltransferase gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14950 SG48_RS14955 SG48_2936 SG48_RS14955 3013300 3016398 + Fe-S subunit oxidoreductase subunit with YgfM and YgfN forms a selenate reductase%2C which seems to catalyze the reduction of selenate to selenite%3B YgfK mutants are unable to reduce selenate%3B involved in purine salvage process%3B seems to act as an oxidoreductase%2C but sequence similarity suggests it is a dihydrothymine dehydrogenase gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14955 SG48_RS14960 SG48_2937 SG48_RS14960 3016401 3017729 + protein SsnA in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14960 SG48_RS14965 SG48_2938 SG48_RS14965 3017780 3018559 + oxidoreductase gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14965 SG48_RS14970 SG48_2939 SG48_RS14970 3018556 3021426 + hypoxanthine oxidase XdhD gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14970 SG48_RS14975 SG48_2940 SG48_RS14975 3021591 3022991 + xanthine permease XanQ high-affinity transporter for xanthine gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14975 SG48_RS14980 SG48_2941 SG48_RS14980 3023009 3024325 + guanine deaminase Catalyzes the deamination of guanine gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14980 SG48_RS14985 SG48_2942 SG48_RS14985 3024361 3025728 + guanine/hypoxanthine permease GhxQ gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14985 SG48_RS14990 SG48_2943 SG48_RS14990 3025764 3026252 - oxidoreductase gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14990 SG48_RS14995 SG48_2944 SG48_RS14995 3026252 3028171 - oxidoreductase Fe-S subunit/nucleotide-binding subunit unknown function%3B in E. coli the aegA gene is regulated by Fnr%2C NarXL%2C and NarQ (but not ArcA)%2C induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS14995 SG48_RS15000 SG48_RS15000 SG48_RS15000 3028474 3028662 + hypothetical protein gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15000 SG48_RS15005 SG48_2945 SG48_RS15005 3028607 3030055 + uric acid transporter UacT gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15005 SG48_RS15010 SG48_2946 SG48_RS15010 3030057 3030182 + hypothetical protein gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15010 SG48_RS15015 SG48_2947 SG48_RS15015 3030305 3030853 + isopentenyl-diphosphate delta isomerase catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15015 SG48_RS15020 SG48_2948 lysS lysS 3030897 3032414 - lysine--tRNA ligase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15020 SG48_RS15025 SG48_RS15025 SG48_RS15025 3032424 3033305 - peptide chain release factor 2 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15025 SG48_RS15030 SG48_2950 SG48_RS15030 3033613 3035346 - single-stranded-DNA-specific exonuclease RecJ 5'-3' single-stranded-DNA-specific exonuclease gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15030 SG48_RS15035 SG48_2951 SG48_RS15035 3035352 3036062 - thiol:disulfide interchange protein DsbC DsbC%3B periplasmic protein with protein disulfide isomerase activity%3B this protein also shows disulfide oxidoreductase activity gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15035 SG48_RS15040 SG48_2952 xerD xerD 3036087 3036983 - tyrosine recombinase XerD site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B XerD specifically exchanges the bottom strands%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15040 SG48_RS15045 SG48_2953 SG48_RS15045 3037095 3037616 + flavodoxin-2 An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15045 SG48_RS15050 SG48_2954 SG48_RS15050 3037656 3038063 - toxin CptA gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15050 SG48_RS15055 SG48_2955 SG48_RS15055 3038044 3038310 - antitoxin CptB gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15055 SG48_RS15060 SG48_2956 ygfZ ygfZ 3038553 3039533 + tRNA-modifying protein YgfZ physiological role is not clear%3B not essential for growth but mutants grow poorly%3B mutations suppress hda null mutations%3B may be involved in regulation of ATP-DnaA levels%3B may also be involved in regulation of tRNA modifications%3B can bind folic acid and tetrahydrofolate%3B forms a three domain ring-like structure with a central channel%3B structurally similar to DMGO protein from A. globiformis%3B shows sequence similarity to yeast CAF17 transcriptional regulato%3B Hda supressor gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15060 SG48_RS15065 SG48_2957 SG48_RS15065 3039729 3040388 - hemolysin gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15065 SG48_RS15070 SG48_2958 SG48_RS15070 3040552 3040863 - hypothetical protein gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15070 SG48_RS15075 SG48_2959 SG48_RS15075 3040908 3042341 + 6-phospho-beta-glucosidase gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15075 SG48_RS15080 SG48_2960 SG48_RS15080 3042398 3043141 - NAD(P)-dependent oxidoreductase gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15080 SG48_RS15085 SG48_2961 SG48_RS15085 3043408 3046281 - glycine dehydrogenase (decarboxylating) acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15085 SG48_RS15090 SG48_2962 SG48_RS15090 3046400 3046789 - glycine cleavage system protein H part of multienzyme complex composed of H%2C L%2C P%2C and T proteins which catalyzes oxidation of glycine to yield carbon dioxide%2C ammonia%2C 5%2C10-CH2-H4folate and a reduced pyridine nucleotide%3B protein H is involved in transfer of methylamine group from the P to T protein%3B covalently bound to a lipoyl cofactor gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15090 SG48_RS15095 SG48_2963 gcvT gcvT 3046813 3047907 - aminomethyltransferase catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate%2C causing the release of ammonia and the generation of reduced GcvH protein gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15095 SG48_RS15100 SG48_2964 SG48_RS15100 3048355 3049557 - 2-octaprenylphenol hydroxylase gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15100 SG48_RS15105 SG48_2965 SG48_RS15105 3049580 3050758 - 2-octaprenyl-6-methoxyphenol hydroxylase Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1%2C4-benzoquinone gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15105 SG48_RS15110 SG48_2966 SG48_RS15110 3050755 3052080 - Xaa-Pro aminopeptidase exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue%3B substrate can be as short as a dipeptide gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15110 SG48_RS15115 SG48_2967 SG48_RS15115 3052106 3052690 - hypothetical protein the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers%3B function unknown gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15115 SG48_RS15120 SG48_2968 SG48_RS15120 3052852 3053181 + cell division protein ZapA gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15120 SG48_RS15125 SG48_2970 SG48_RS15125 3053427 3054029 + 5-formyltetrahydrofolate cyclo-ligase ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms%3B unknown function gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15125 SG48_RS15130 SG48_2973 SG48_RS15130 3054418 3055650 - D-3-phosphoglycerate dehydrogenase catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis%3B can also reduce alpha ketoglutarate to form 2-hydroxyglutarate gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15130 SG48_RS15135 SG48_2974 SG48_RS15135 3055906 3056565 - ribose-5-phosphate isomerase A catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15135 SG48_RS15140 SG48_RS15140 SG48_RS15140 3056621 3056851 - hypothetical protein gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15140 SG48_RS15145 SG48_2976 SG48_RS15145 3056993 3057886 + chromosome initiation inhibitor specific inhibitor of chromosomal initiation of replication in vitro%3B binds the three 13-mers in the origin (oriC) to block initiation of replication%3B also controls genes involved in arginine transport gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15145 SG48_RS15150 SG48_2977 SG48_RS15150 3058090 3060234 + methylmalonyl-CoA mutase gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15150 SG48_RS15155 SG48_2978 SG48_RS15155 3060227 3061222 + GTPase ArgK gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15155 SG48_RS15160 SG48_2979 SG48_RS15160 3061233 3062018 + methylmalonyl-CoA decarboxylase catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15160 SG48_RS15165 SG48_2980 SG48_RS15165 3062042 3063520 + propionyl-CoA--succinate CoA transferase gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15165 SG48_RS15170 SG48_2981 SG48_RS15170 3063517 3064413 - transcriptional regulator gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15170 SG48_RS15175 SG48_2982 SG48_RS15175 3064580 3065320 - oxidative stress defense protein gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15175 SG48_RS15180 SG48_2983 SG48_RS15180 3065413 3066006 - arginine exporter protein Involved in the export of arginine gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15180 SG48_RS15185 SG48_2984 SG48_RS15185 3066187 3067047 - small-conductance mechanosensitive channel participates in the regulation of osmotic pressure changes within the cel gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15185 SG48_RS15190 SG48_2985 SG48_RS15190 3067405 3068484 - fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15190 SG48_RS15195 SG48_2986 SG48_RS15195 3068699 3069862 - phosphoglycerate kinase gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15195 SG48_RS15200 SG48_2987 gapA gapA 3069912 3070931 - D-erythrose-4-phosphate dehydrogenase required for glycolysis%3B catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15200 SG48_RS15205 SG48_2988 SG48_RS15205 3071216 3071929 - PanK family P-loop kinase gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15205 SG48_RS15210 SG48_2989 SG48_RS15210 3071926 3072435 - MtlR family transcriptional regulator gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15210 SG48_RS15215 SG48_2990 SG48_RS15215 3072457 3073422 - fructose 1%2C6-bisphosphatase gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15215 SG48_RS15220 SG48_2991 SG48_RS15220 3073419 3074696 - Zn-binding dehydrogenase gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15220 SG48_RS15225 SG48_2992 SG48_RS15225 3074711 3076099 - PTS mannitol cryptic EIICB component CmtA with CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system%2C which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli%3B cytoplasmic protein gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15225 SG48_RS15230 SG48_2993 cmtB cmtB 3076127 3076570 - mannitol-specific cryptic phosphotransferase enzyme IIA component TolM%3B with CmtA (IIBC)%2C CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system%2C which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli%3B cytoplasmic protein gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15230 SG48_RS15235 SG48_2994 SG48_RS15235 3076884 3078875 - transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15235 SG48_RS15240 SG48_2995 SG48_RS15240 3079153 3079911 + metalloprotease LoiP gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15240 SG48_RS15245 SG48_2996 SG48_RS15245 3080117 3081037 - agmatinase catalyzes the formation of putrescine from agmatine gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15245 SG48_RS15250 SG48_2997 SG48_RS15250 3081175 3083151 - biosynthetic arginine decarboxylase catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15250 SG48_RS15255 SG48_2998 SG48_RS15255 3083160 3083291 - hypothetical protein gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15255 SG48_RS15260 SG48_2999 SG48_RS15260 3083427 3083642 + hypothetical protein gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15260 SG48_RS15265 SG48_RS15265 SG48_RS15265 3083639 3083890 - membrane protein gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15265 SG48_RS15270 SG48_3000 SG48_RS15270 3083946 3085100 + S-adenosylmethionine synthase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15270 SG48_RS15275 SG48_3001 SG48_RS15275 3085524 3086918 + galactose-proton symporter gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15275 SG48_RS15280 SG48_3002 SG48_RS15280 3086995 3087492 + protein SprT gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15280 SG48_RS15285 SG48_3003 SG48_RS15285 3087587 3088294 + endonuclease-1 gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15285 SG48_RS15290 SG48_3004 SG48_RS15290 3088374 3089105 + ribosomal RNA small subunit methyltransferase E in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA%3B cells lacking this function can grow%2C but are outcompeted by wild-type%3B SAM-dependent m(3)U1498 methyltransferase gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15290 SG48_RS15295 SG48_3005 SG48_RS15295 3089118 3090068 + glutathione synthetase catalyzes the second step in the glutathione biosynthesis pathway%2C where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine %3D ADP + phosphate + glutathione gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15295 SG48_RS15300 SG48_3006 SG48_RS15300 3090177 3090740 + hypothetical protein gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15300 SG48_RS15305 SG48_3007 SG48_RS15305 3090740 3091156 + Holliday junction DNA helicase similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15305 SG48_RS15310 SG48_3008 SG48_RS15310 3091340 3092320 - PilT family AAA+ ATPase gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15310 SG48_RS15315 SG48_3009 SG48_RS15315 3092338 3093042 + YggS family pyridoxal phosphate enzyme gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15315 SG48_RS15320 SG48_3010 SG48_RS15320 3093060 3093626 + hypothetical protein gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15320 SG48_RS15325 SG48_3011 SG48_RS15325 3093623 3093913 + hypothetical protein gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15325 SG48_RS15330 SG48_3012 SG48_RS15330 3093921 3094514 + non-canonical purine NTP pyrophosphatase HAM1-like protein%3B Rec-dependent growth%3B RgdB%3B yggV%3B it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15330 SG48_RS15335 SG48_3013 SG48_RS15335 3094507 3095643 + coproporphyrinogen III oxidase gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15335 SG48_RS15340 SG48_3014 SG48_RS15340 3095798 3096805 - DUF1202 domain-containing protein gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15340 SG48_RS15345 SG48_3015 ansB ansB 3096922 3097968 - L-asparaginase 2 catalyzes the formation of aspartate from asparagine%2C periplasmic%3B regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15345 SG48_RS15350 SG48_3016 SG48_RS15350 3098144 3098863 - hypothetical protein gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15350 SG48_RS15355 SG48_RS15355 SG48_RS15355 3098884 3099024 - hypothetical protein gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15355 SG48_RS15360 SG48_3017 SG48_RS15360 3099047 3099373 - hypothetical protein gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15360 SG48_RS15365 SG48_3018 trmB trmB 3099373 3100092 - tRNA (guanine-N(7)-)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase%3B catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15365 SG48_RS15370 SG48_3019 SG48_RS15370 3100253 3101305 + A/G-specific adenine glycosylase gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15370 SG48_RS15375 SG48_3020 SG48_RS15375 3101333 3101608 + Fe(2+)-trafficking protein protects iron-sulfur proteins against oxidative damage gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15375 SG48_RS15380 SG48_3021 mltC mltC 3101673 3102752 + murein transglycosylase Murein hydrolase C%3B membrane-bound%3B lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15380 SG48_RS15385 SG48_3022 SG48_RS15385 3102954 3104210 + nucleoside permease NupG gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15385 SG48_RS15390 SG48_3023 SG48_RS15390 3104260 3106395 - ornithine decarboxylase gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15390 SG48_RS15395 SG48_3024 SG48_RS15395 3106793 3107500 + DUF554 domain-containing protein gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15395 SG48_RS15400 SG48_3025 SG48_RS15400 3107606 3107681 + tRNA-Phe tRNA gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15400 SG48_RS15405 SG48_3026 SG48_RS15405 3107830 3108366 - membrane-anchored secretion pathway M-type protein gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15405 SG48_RS15410 SG48_RS15410 SG48_RS15410 3108368 3109228 - type II secretion system protein GspL gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15410 SG48_RS15415 SG48_RS15415 SG48_RS15415 3109294 3110289 - type II secretion system protein GspC part of the general (type II) secretion pathway (GSP)%2C a signal sequence-dependent process responsible for protein export%3B involved in trans-location of exoproteins from the cytoplasm to the periplasm gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15415 SG48_RS15420 SG48_3029 SG48_RS15420 3110307 3110717 - secretin (GspDbeta) OM localization lipoprotein pilotin gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15420 SG48_RS15425 SG48_3030 SG48_RS15425 3110783 3111592 - leader peptidase PppA gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15425 SG48_RS15430 SG48_3031 SG48_RS15430 3111790 3116352 - and surface-associated lipoprotein mucinase gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15430 SG48_RS15435 SG48_RS15435 SG48_RS15435 3116503 3116685 + hypothetical protein gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15435 SG48_RS15440 SG48_3032 SG48_RS15440 3116837 3118519 - glycolate permease GlcA gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15440 SG48_RS15445 SG48_3033 SG48_RS15445 3118874 3121045 - malate synthase G gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15445 SG48_RS15450 SG48_3034 SG48_RS15450 3121067 3121471 - protein GlcG gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15450 SG48_RS15455 SG48_3035 glcF glcF 3121476 3122699 - glycolate oxidase gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15455 SG48_RS15460 SG48_3036 glcE glcE 3122710 3123762 - glycolate oxidase gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15460 SG48_RS15465 SG48_3037 SG48_RS15465 3123762 3125261 - glycolate oxidase gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15465 SG48_RS15470 SG48_3038 SG48_RS15470 3125512 3126276 + glc operon transcriptional activator gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15470 SG48_RS15475 SG48_RS15475 SG48_RS15475 3126283 3127419 - DNA-binding protein gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15475 SG48_RS15480 SG48_3040 SG48_RS15480 3127454 3128434 + transposase gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15480 SG48_RS15485 SG48_3041 SG48_RS15485 3128581 3129648 - hypothetical protein gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15485 SG48_RS15490 SG48_3042 SG48_RS15490 3129694 3130452 - ATP-binding protein gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15490 SG48_RS15495 SG48_3043 SG48_RS15495 3130484 3131182 - hypothetical protein gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15495 SG48_RS15500 SG48_3044 SG48_RS15500 3131371 3132063 + ATP-binding protein gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15500 SG48_RS15505 SG48_3045 SG48_RS15505 3132112 3133611 - low-affinity inorganic phosphate transporter 2 involved in the transport of inorganic phosphate gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15505 SG48_RS15510 SG48_3046 SG48_RS15510 3133903 3135762 - bifunctional glutathionylspermidine synthetase/amidase catalyzes the formation of glutathionylspermidine from glutathione and spermidine%3B also catalyzes the reverse reaction gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15510 SG48_RS15515 SG48_3047 SG48_RS15515 3135967 3136833 + disulfide-bond oxidoreductase YghU YghU%3B B2989%3B one of eight putative glutathione transferase proteins from E. coli gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15515 SG48_RS15520 SG48_3048 SG48_RS15520 3136956 3137204 - hydrogenase-2 operon protein HybG gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15520 SG48_RS15525 SG48_3049 hypA hypA 3137217 3137558 - hydrogenase nickel incorporation protein plays a role in hydrogenase nickel cofactor insertion gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15525 SG48_RS15530 SG48_3050 SG48_RS15530 3137551 3138039 - hydrogenase-2 operon protein HybE gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15530 SG48_RS15535 SG48_3051 hybD hybD 3138032 3138526 - hydrogenase 2 maturation protease protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15535 SG48_RS15540 SG48_3052 SG48_RS15540 3138526 3140229 - hydrogenase-2 large chain involved in hydrogen uptake gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15540 SG48_RS15545 SG48_3053 SG48_RS15545 3140226 3141404 - Ni/Fe-hydrogenase b-type cytochrome subunit HybB%3B cytochrome b subunit of the hydrogenase 2 enzyme%2C composed of HybA%2C B%2C C%2C and O subunits gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15545 SG48_RS15550 SG48_3054 SG48_RS15550 3141394 3142380 - hydrogenase-2 operon protein HybA Fe-S ferrodoxin type component%3B participates in the periplasmic electron-transferring activity of hydrogenase 2 gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15550 SG48_RS15555 SG48_3055 SG48_RS15555 3142383 3143501 - hydrogenase-2 small chain involved in hydrogen uptake gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15555 SG48_RS15560 SG48_RS15560 SG48_RS15560 3143508 3143693 - hypothetical protein gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15560 SG48_RS15565 SG48_3056 SG48_RS15565 3143690 3143977 - hypothetical protein gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15565 SG48_RS15570 SG48_RS15570 SG48_RS15570 3144096 3144980 - dienelactone hydrolase gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15570 SG48_RS15575 SG48_3058 SG48_RS15575 3145137 3146177 + glyceraldehyde 3-phosphate reductase gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15575 SG48_RS15580 SG48_3059 SG48_RS15580 3146217 3146711 - hypothetical protein gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15580 SG48_RS15585 SG48_3060 SG48_RS15585 3146902 3147786 + oxidoreductase gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15585 SG48_RS15590 SG48_3061 SG48_RS15590 3148058 3148483 - biopolymer transporter ExbD membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15590 SG48_RS15595 SG48_3062 SG48_RS15595 3148490 3149224 - biopolymer transporter ExbB membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15595 SG48_RS15600 SG48_RS15600 SG48_RS15600 3149217 3149354 - membrane protein gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15600 SG48_RS15605 SG48_3063 SG48_RS15605 3149476 3150663 + cystathionine beta-lyase MetC catalyzes the formation of L-homocysteine from cystathionine gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15605 SG48_RS15610 SG48_3064 SG48_RS15610 3150803 3151462 + hypothetical protein gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15610 SG48_RS15615 SG48_3065 SG48_RS15615 3151502 3152401 - AraC family transcriptional regulator gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15615 SG48_RS15620 SG48_RS15620 SG48_RS15620 3152398 3152544 - hypothetical protein gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15620 SG48_RS15625 SG48_3066 SG48_RS15625 3152595 3153758 + alcohol dehydrogenase gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15625 SG48_RS15630 SG48_3067 dkgA dkgA 3153863 3154690 + 2%2C5-diketo-D-gluconic acid reductase A methylglyoxal reductase/beta-keto ester reductase%3B catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid%3B also catalyzes the reduction of methylglyoxal%2C ethyl-2-methylacetoacetate and ethyl-acetoacetate gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15630 SG48_RS15635 SG48_3068 SG48_RS15635 3154890 3155816 + DUF3828 domain-containing protein gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15635 SG48_RS15640 SG48_3069 SG48_RS15640 3155867 3156124 + hypothetical protein gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15640 SG48_RS15645 SG48_3070 SG48_RS15645 3156167 3158386 - Radical SAM superfamily protein gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15645 SG48_RS15650 SG48_3071 SG48_RS15650 3158497 3159909 - cell division protein FtsP septal ring component that protects the divisome from stress gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15650 SG48_RS15655 SG48_3072 SG48_RS15655 3159984 3160721 - 1-acyl-sn-glycerol-3-phosphate acyltransferase catalyzes the formation of 1%2C2-diacyl-sn-glycerol 3-phosphate from 1-acyl-sn-glycerol 3-phosphate using either acyl-CoA or acyl-ACP gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15655 SG48_RS15660 SG48_3073 SG48_RS15660 3160955 3163213 - DNA topoisomerase 4 subunit A decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15660 SG48_RS15665 SG48_3074 SG48_RS15665 3163351 3164958 - ABC transporter permease gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15665 SG48_RS15670 SG48_3075 SG48_RS15670 3165091 3165486 - antitoxin gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15670 SG48_RS15675 SG48_3076 SG48_RS15675 3165488 3165784 - mRNA interferase MqsR gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15675 SG48_RS15680 SG48_3077 SG48_RS15680 3165989 3166471 - transcriptional regulator gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15680 SG48_RS15685 SG48_3078 SG48_RS15685 3166524 3166916 - hypothetical protein gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15685 SG48_RS15690 SG48_3079 SG48_RS15690 3167068 3167727 + two-component system response regulator response regulator in two-component regulatory system with QseC%3B regulates FlhCD which is the master regulator for flagella and motility genes gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15690 SG48_RS15695 SG48_3080 SG48_RS15695 3167724 3169073 + two-component system sensor histidine kinase gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15695 SG48_RS15700 SG48_3081 SG48_RS15700 3169119 3169451 - hypothetical protein gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15700 SG48_RS15705 SG48_3082 SG48_RS15705 3169770 3170351 + modulator of drug activity B involved in drug resistance gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15705 SG48_RS15710 SG48_3083 SG48_RS15710 3170382 3170696 + quinol monooxygenase YgiN catalyzes the oxidation of menadiol to menadione gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15710 SG48_RS15715 SG48_3084 SG48_RS15715 3170744 3172636 - DNA topoisomerase 4 subunit B decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15715 SG48_RS15720 SG48_3085 SG48_RS15720 3172665 3173246 - esterase Displays esterase activity toward palmitoyl-CoA and pNP-butyrate gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15720 SG48_RS15725 SG48_3086 SG48_RS15725 3173246 3174073 - 3'%2C5'-cyclic adenosine monophosphate phosphodiesterase CpdA gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15725 SG48_RS15730 SG48_3087 SG48_RS15730 3174098 3174520 - dehydrogenase gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15730 SG48_RS15735 SG48_3088 nudF nudF 3174521 3175150 - ADP-ribose pyrophosphatase ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15735 SG48_RS15740 SG48_3089 tolC tolC 3175355 3176836 + outer membrane protein TolC trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules%3B functions with a number of efflux systems in the inner membrane to transport molecules out of the cell gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15740 SG48_RS15745 SG48_RS15745 SG48_RS15745 3176836 3177096 + hypothetical protein gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15745 SG48_RS15750 SG48_3090 SG48_RS15750 3176984 3177655 + membrane protein gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15750 SG48_RS15755 SG48_3091 SG48_RS15755 3177661 3178821 + ATP-Grasp family ATPase gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15755 SG48_RS15760 SG48_3092 SG48_RS15760 3178859 3179647 - 4%2C5- DOPA-extradiol-dioxygenase seems to be involved in biofilm formation%3B in asymptomatic bacteriuria E. coli strains 83972 and VR50%2C the ygiD gene is upregulated during biofilm formation in urine gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15760 SG48_RS15765 SG48_3093 SG48_RS15765 3179790 3180563 + zinc transporter ZupT gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15765 SG48_RS15770 SG48_RS15770 SG48_RS15770 3180621 3180791 - hypothetical protein gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15770 SG48_RS15775 SG48_3094 ribB ribB 3181053 3181706 - 3%2C4-dihydroxy-2-butanone 4-phosphate synthase DHBP synthase%3B functions during riboflavin biosynthesis gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15775 SG48_RS15780 SG48_3095 SG48_RS15780 3182080 3182370 + BMFP family fusogenic protein gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15780 SG48_RS15785 SG48_3096 SG48_RS15785 3182654 3183205 + fimbrial-like adhesin protein gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15785 SG48_RS15790 SG48_3098 SG48_RS15790 3183427 3183792 + transposase represses IS2 gene transcription gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15790 SG48_RS15795 SG48_3099 SG48_RS15795 3183750 3184655 + integrase gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15795 SG48_RS15800 SG48_RS15800 SG48_RS15800 3184640 3187105 + fimbrial outer membrane usher protein StdB gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15800 SG48_RS15805 SG48_3100 SG48_RS15805 3187121 3187870 + periplasmic pilin chaperone gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15805 SG48_RS15810 SG48_3101 SG48_RS15810 3187872 3188936 + fimbrial protein gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15810 SG48_RS15815 SG48_3102 SG48_RS15815 3188979 3189179 - glycogen synthase Involved in glycogen synthesis. May be involved in glycogen priming gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15815 SG48_RS15820 SG48_3103 SG48_RS15820 3189448 3190077 + hypothetical protein gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15820 SG48_RS15825 SG48_3104 SG48_RS15825 3190104 3191765 + hypothetical protein gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15825 SG48_RS15830 SG48_RS15830 SG48_RS15830 3191866 3192118 + hypothetical protein gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15830 SG48_RS15835 SG48_RS15835 SG48_RS15835 3192102 3192493 + hypothetical protein gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15835 SG48_RS15840 SG48_3109 SG48_RS15840 3192560 3193993 - bifunctional protein HldE catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D%2CD-heptose-1%2C7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D%2CD-heptose gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15840 SG48_RS15845 SG48_3110 SG48_RS15845 3194041 3196881 - glutamate--ammonia-ligase adenylyltransferase catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase%3B also catalyzes the reverse reaction - deadenylation%3B adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15845 SG48_RS15850 SG48_3111 SG48_RS15850 3196904 3198205 - inorganic triphosphatase gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15850 SG48_RS15855 SG48_RS15855 SG48_RS15855 3198222 3198407 - hypothetical protein gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15855 SG48_RS15860 SG48_3112 SG48_RS15860 3198447 3199067 + signal transduction protein gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15860 SG48_RS15865 SG48_3113 SG48_RS15865 3199131 3200369 + multifunctional CCA protein gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15865 SG48_RS15870 SG48_3114 SG48_RS15870 3200550 3201371 - undecaprenyl-diphosphatase BacA%3B phosphatase activity in Escherichia coli not kinase%3B involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15870 SG48_RS15875 SG48_3115 folB folB 3201461 3201829 - dihydroneopterin aldolase catalyzes the conversion of 7%2C8-dihydroneopterin to 6-hydroxymethyl-7%2C8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15875 SG48_RS15880 SG48_3116 SG48_RS15880 3201934 3202551 + glycerol-3-phosphate acyltransferase involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis%3B functions with PlsX gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15880 SG48_RS15885 SG48_3117 SG48_RS15885 3202564 3203496 - transcriptional activator TtdR gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15885 SG48_RS15890 SG48_3118 SG48_RS15890 3203706 3204614 + tartrate dehydratase subunit alpha Involved in the tartrate degradation pathway gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15890 SG48_RS15895 SG48_3119 SG48_RS15895 3204611 3205216 + L+-tartrate dehydratase subunit beta Involved in the tartrate degradation pathway gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15895 SG48_RS15900 SG48_3120 SG48_RS15900 3205264 3206727 + L-tartrate/succinate antiporter involved in the transport of citrate into the cell along with the export of succinate out of the cell gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15900 SG48_RS15905 SG48_3121 SG48_RS15905 3206770 3207783 - tRNA N6-adenosine threonylcarbamoyltransferase universal genome maintenance protein%3B Kae1/Qri7/OSGEP/YgjD family protein%3B in Archaea%2C some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex%3B kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32)%3B in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32%3B the protein is essential in Escherichia coli and Bacillus subtilis gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15905 SG48_RS15910 SG48_3122 rpsU rpsU 3208021 3208236 + 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15910 SG48_RS15915 SG48_3123 dnaG dnaG 3208347 3210092 + DNA primase synthesizes RNA primers at the replication forks gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15915 SG48_RS15920 SG48_3124 SG48_RS15920 3210287 3212128 + RNA polymerase sigma factor RpoD sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this is the primary sigma factor of bacteria gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15920 SG48_RS15925 SG48_3125 SG48_RS15925 3212207 3212713 - G/U mismatch DNA glycosylase gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15925 SG48_RS15930 SG48_3126 SG48_RS15930 3212838 3212913 + tRNA-Met tRNA gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15930 SG48_RS15935 SG48_3127 SG48_RS15935 3212967 3213731 - NADPH-dependent ferric-chelate reductase gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15935 SG48_RS15940 SG48_3128 SG48_RS15940 3214019 3214642 + transcriptional regulator gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15940 SG48_RS15945 SG48_3129 SG48_RS15945 3214796 3216316 - aerotaxis receptor gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15945 SG48_RS15950 SG48_3130 SG48_RS15950 3216734 3218113 + putrescine aminotransferase catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15950 SG48_RS15955 SG48_3131 SG48_RS15955 3218155 3218487 - tRNA-binding protein gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15955 SG48_RS15960 SG48_3132 SG48_RS15960 3218706 3219689 + transcriptional regulator gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15960 SG48_RS15965 SG48_3133 ebgA ebgA 3219873 3222965 + evolved beta-galactosidase subunit alpha in Escherichia coli this is the second beta-galactosidase system gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15965 SG48_RS15970 SG48_3134 ebgC ebgC 3222962 3223411 + evolved beta-galactosidase subunit beta in Escherichia coli this is the second beta-galactosidase system gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15970 SG48_RS15975 SG48_3135 SG48_RS15975 3223474 3224907 + inner membrane transporter YgjI gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15975 SG48_RS15980 SG48_3136 SG48_RS15980 3225041 3226111 + periplasmic protein gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15980 SG48_RS15985 SG48_3137 SG48_RS15985 3226128 3228479 + glucosidase YgjK gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15985 SG48_RS15990 SG48_3138 SG48_RS15990 3228905 3230923 + 2%2C4-dienoyl-CoA reductase [NADPH] gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15990 SG48_RS15995 SG48_3139 SG48_RS15995 3230968 3231384 - antitoxin HigA gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS15995 SG48_RS16000 SG48_3140 SG48_RS16000 3231381 3231695 - mRNA interferase HigB gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16000 SG48_RS16005 SG48_RS16005 SG48_RS16005 3231637 3231876 - toxin RelE gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16005 SG48_RS16010 SG48_3141 SG48_RS16010 3231979 3233115 - ribosomal RNA large subunit methyltransferase G gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16010 SG48_RS16015 SG48_3142 SG48_RS16015 3233200 3233703 + metal dependent hydrolase gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16015 SG48_RS16020 SG48_3143 SG48_RS16020 3233780 3234472 + DUF218 domain-containing protein gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16020 SG48_RS16025 SG48_3144 SG48_RS16025 3234551 3235537 + NAD(P)-dependent dehydrogenase gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16025 SG48_RS16030 SG48_3145 SG48_RS16030 3235820 3236785 + hypothetical protein gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16030 SG48_RS16035 SG48_3146 SG48_RS16035 3237184 3238428 + serine/threonine transporter SstT involved in the import of serine and threonine coupled with the import of sodium gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16035 SG48_RS16040 SG48_3147 SG48_RS16040 3238433 3238984 - hypothetical protein gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16040 SG48_RS16045 SG48_3148 SG48_RS16045 3239067 3240554 - altronate dehydratase gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16045 SG48_RS16050 SG48_3149 SG48_RS16050 3240569 3241981 - uronate isomerase catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate%3B functions in glucuronic and galacturonic metabolism gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16050 SG48_RS16055 SG48_3150 SG48_RS16055 3242464 3243762 + hexuronate transporter involved in the transport of aldohexuronates gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16055 SG48_RS16060 SG48_3151 SG48_RS16060 3243892 3244668 + exu regulon transcriptional regulator regulates the expression of uxuBA gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16060 SG48_RS16065 SG48_3152 SG48_RS16065 3245013 3245675 + hypothetical protein gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16065 SG48_RS16070 SG48_3153 SG48_RS16070 3245679 3246062 + modulator protein MzrA gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16070 SG48_RS16075 SG48_3154 SG48_RS16075 3246209 3246577 + hypothetical protein gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16075 SG48_RS16080 SG48_3155 SG48_RS16080 3246615 3246920 + hypothetical protein gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16080 SG48_RS16085 SG48_3156 SG48_RS16085 3246923 3247327 + hypothetical protein gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16085 SG48_RS16090 SG48_3157 SG48_RS16090 3247317 3247616 + hypothetical protein gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16090 SG48_RS16095 SG48_3158 SG48_RS16095 3247802 3248194 + hypothetical protein gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16095 SG48_RS16100 SG48_3159 SG48_RS16100 3248264 3249250 + glutathionyl-hydroquinone reductase YqjG gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16100 SG48_RS16105 SG48_3160 SG48_RS16105 3249544 3249909 + hypothetical protein gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16105 SG48_RS16110 SG48_3161 SG48_RS16110 3250151 3250507 + hypothetical protein gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16110 SG48_RS16115 SG48_3162 SG48_RS16115 3250558 3251454 - LysR family transcriptional regulator gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16115 SG48_RS16120 SG48_3163 SG48_RS16120 3251559 3252260 + pirin-like protein YhaK gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16120 SG48_RS16125 SG48_3164 SG48_RS16125 3252280 3252447 + hypothetical protein gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16125 SG48_RS16130 SG48_3165 SG48_RS16130 3252581 3253891 - L-serine dehydratase alpha chain gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16130 SG48_RS16135 SG48_3166 SG48_RS16135 3253919 3255250 - transporter gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16135 SG48_RS16140 SG48_3167 SG48_RS16140 3255525 3256889 - L-serine dehydratase TdcG catalyzes the formation of pyruvate from serine gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16140 SG48_RS16145 SG48_3168 SG48_RS16145 3256961 3257350 - reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16145 SG48_RS16150 SG48_3169 SG48_RS16150 3257364 3259658 - PFL-like enzyme TdcE formate acetyltransferase%3B catalyzes the formation of formate and acetyl-CoA from pyruvate gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16150 SG48_RS16155 SG48_3170 SG48_RS16155 3259692 3260900 - propionate kinase catalyzes the formation of propanoyl phosphate from propanoate and ATP%3B TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16155 SG48_RS16160 SG48_3171 SG48_RS16160 3260926 3262257 - threonine/serine transporter TdcC gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16160 SG48_RS16165 SG48_3172 SG48_RS16165 3262279 3263268 - L-threonine dehydratase catabolic TdcB catalyzes the formation of 2-oxobutanoate from L-threonine%3B catabolic gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16165 SG48_RS16170 SG48_3173 SG48_RS16170 3263367 3264305 - transcriptional regulator regulates the tdcABCDEFG operon which is involved in amino acid degradation gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16170 SG48_RS16175 SG48_RS16175 SG48_RS16175 3264494 3264838 + transcriptional regulator participates in controlling the expression of several structural genes for the enzyme threonine dehydratase%3B TdcR activates the tdcABCDEFG operon gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16175 SG48_RS16180 SG48_3175 SG48_RS16180 3265094 3265633 + hypothetical protein gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16180 SG48_RS16185 SG48_3176 SG48_RS16185 3265655 3266842 + pentapetide repeats-related protein gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16185 SG48_RS16190 SG48_3178 SG48_RS16190 3267865 3269010 - glycerate 2-kinase gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16190 SG48_RS16195 SG48_3179 garR garR 3269107 3269997 - 2-hydroxy-3-oxopropionate reductase catalyzes the reduction of tartronate semialdehyde to glycerate gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16195 SG48_RS16200 SG48_3180 SG48_RS16200 3270027 3270797 - 5-keto-4-deoxy-D-glucarate aldolase cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16200 SG48_RS16205 SG48_3181 SG48_RS16205 3270813 3272147 - galactarate transporter gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16205 SG48_RS16210 SG48_3182 garD garD 3272522 3274093 + D-galactarate dehydratase catalyzes the formation of 5-dehydro-4-deoxy-D-glucarate from D-galactarate gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16210 SG48_RS16215 SG48_3183 SG48_RS16215 3274242 3274577 + antitoxin PrlF SohA%3B PrlF%3B involved in protein secretion%3B when overproduced or mutated%2C it induces growth defect and increased export of a reporter protein%3B a PrlF mutation induces the activity of the Lon protease%2C and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16215 SG48_RS16220 SG48_3184 SG48_RS16220 3274577 3275041 + toxin YhaV gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16220 SG48_RS16225 SG48_3185 SG48_RS16225 3275096 3275905 - DeoR family transcriptional regulator transcriptional repressor for the agaZVWA and agaSYBCDI operons gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16225 SG48_RS16230 SG48_3186 SG48_RS16230 3276154 3277434 + tagatose-1%2C6-bisphosphate aldolase with KbaY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1%2C6-bisphosphate%3B subunit Z may act as a chaperone for the Y subunit gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16230 SG48_RS16235 SG48_3187 SG48_RS16235 3277457 3277930 + N-acetylgalactosamine-specific phosphotransferase enzyme IIB component 2 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16235 SG48_RS16240 SG48_RS16240 SG48_RS16240 3277941 3278342 + N-acetylgalactosamine permease IIC protein 2 gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16240 SG48_RS16245 SG48_RS16245 SG48_RS16245 3278362 3278865 + N-acetylgalactosamine-6-phosphate deacetylase gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16245 SG48_RS16250 SG48_3190 SG48_RS16250 3279216 3280370 + tagatose-6-phosphate ketose isomerase gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16250 SG48_RS16255 SG48_3191 kbaY kbaY 3280383 3281243 + tagatose-1%2C6-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16255 SG48_RS16260 SG48_3192 SG48_RS16260 3281410 3281886 + N-acetylgalactosamine-specific phosphotransferase enzyme IIB component 1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16260 SG48_RS16265 SG48_3193 SG48_RS16265 3281925 3282728 + N-acetylgalactosamine permease IIC component 1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3Bprotein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16265 SG48_RS16270 SG48_3194 SG48_RS16270 3282718 3283509 + N-acetylgalactosamine permease IID component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IID with IIC forms the translocation channel%3B involved in N-acetylgalactosamine transport gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16270 SG48_RS16275 SG48_3195 SG48_RS16275 3283564 3284265 + galactosamine-6-phosphate isomerase gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16275 SG48_RS16280 SG48_3196 SG48_RS16280 3284666 3285250 + fimbrial-like adhesin protein gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16280 SG48_RS16285 SG48_3197 SG48_RS16285 3285330 3286025 + fimbrial chaperone gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16285 SG48_RS16290 SG48_3198 SG48_RS16290 3286054 3288570 + outer membrane usher protein YraJ gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16290 SG48_RS16295 SG48_3199 SG48_RS16295 3288581 3289672 + fimbrial-like adhesin protein gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16295 SG48_RS16300 SG48_3200 SG48_RS16300 3289715 3290575 - ribosomal RNA small subunit methyltransferase I gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16300 SG48_RS16305 SG48_3201 SG48_RS16305 3290640 3292676 + penicillin-binding protein activator LpoA gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16305 SG48_RS16310 SG48_3202 SG48_RS16310 3292634 3293029 + hypothetical protein gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16310 SG48_RS16315 SG48_3203 SG48_RS16315 3293049 3293639 + DnaA initiator-associating protein DiaA Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16315 SG48_RS16320 SG48_3204 SG48_RS16320 3293649 3294224 + hypothetical protein gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16320 SG48_RS16325 SG48_3205 SG48_RS16325 3294338 3295378 - permease gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16325 SG48_RS16330 SG48_3206 SG48_RS16330 3295451 3296086 - nucleoside-diphosphate-sugar epimerase gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16330 SG48_RS16335 SG48_3207 SG48_RS16335 3296214 3296732 + hypothetical protein gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16335 SG48_RS16340 SG48_3208 SG48_RS16340 3296712 3297155 - hypothetical protein gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16340 SG48_RS16345 SG48_3209 SG48_RS16345 3297206 3297508 + nuclease superfamily protein gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16345 SG48_RS16350 SG48_3210 SG48_RS16350 3297495 3297998 - N-acetyltransferase gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16350 SG48_RS16355 SG48_3211 SG48_RS16355 3297992 3298516 - SCP-2 sterol transfer family protein gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16355 SG48_RS16360 SG48_3212 SG48_RS16360 3298725 3299720 + U32 peptidase gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16360 SG48_RS16365 SG48_3213 SG48_RS16365 3299729 3300607 + U32 peptidase gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16365 SG48_RS16370 SG48_3214 SG48_RS16370 3300688 3301695 + luciferase-like monooxygenase gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16370 SG48_RS16375 SG48_3215 SG48_RS16375 3301813 3303057 - tryptophan-specific transporter tryptophan transporter of high affinity gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16375 SG48_RS16380 SG48_RS16380 SG48_RS16380 3303073 3303210 + hypothetical protein gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16380 SG48_RS16385 SG48_3216 SG48_RS16385 3303211 3305100 - DEAD/DEAH box family ATP-dependent RNA helicase participates in the assembly of the large subunit of the ribosome%3B plays a key role in optimal cell growth at low temperature and is required for normal cell division gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16385 SG48_RS16390 SG48_3218 SG48_RS16390 3305280 3306164 - lipoprotein NlpI lipoprotein that appears to be involved in cell division%3B interacts with the periplasmic protease Prc and may be activated by protease processing gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16390 SG48_RS16395 SG48_3219 SG48_RS16395 3306273 3308408 - polyribonucleotide nucleotidyltransferase gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16395 SG48_RS16400 SG48_3221 SG48_RS16400 3308655 3308924 - 30S ribosomal protein S15 gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16400 SG48_RS16405 SG48_3222 truB truB 3309073 3310017 - tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16405 SG48_RS16410 SG48_3223 rbfA rbfA 3310017 3310418 - ribosome-binding factor A associates with free 30S ribosomal subunits%3B essential for efficient processing of 16S rRNA%3B in Escherichia coli rbfA is induced by cold shock gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16410 SG48_RS16415 SG48_3224 infB infB 3310582 3313254 - translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16415 SG48_RS16420 SG48_3225 nusA nusA 3313279 3314766 - transcription termination/antitermination protein NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16420 SG48_RS16425 SG48_3226 SG48_RS16425 3314794 3315246 - ribosome maturation factor RimP required for the maturation of the 30S ribosomal subunits gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16425 SG48_RS16430 SG48_3227 SG48_RS16430 3315453 3315529 - tRNA-Met tRNA gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16430 SG48_RS16435 SG48_3228 SG48_RS16435 3315877 3317220 + argininosuccinate synthase catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16435 SG48_RS16440 SG48_3229 SG48_RS16440 3317228 3318745 - phosphate starvation-inducible protein PsiE gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16440 SG48_RS16445 SG48_3230 SG48_RS16445 3319312 3319398 - tRNA-Leu tRNA gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16445 SG48_RS16450 SG48_3231 secG secG 3319413 3319745 - protein-export membrane protein SecG gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16450 SG48_RS16455 SG48_3232 glmM glmM 3319973 3321310 - phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16455 SG48_RS16460 SG48_3233 folP folP 3321303 3322151 - dihydropteroate synthase catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate and 4-aminobenzoate gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16460 SG48_RS16465 SG48_3234 hflB hflB 3322241 3324175 - ATP-dependent zinc metalloprotease FtsH inner membrane metalloprotease%3B may be involved in degradation of aberrant cytoplasmic and membrane proteins gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16465 SG48_RS16470 SG48_3235 rrmJ rrmJ 3324275 3324904 - ribosomal RNA large subunit methyltransferase E Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16470 SG48_RS16475 SG48_3236 SG48_RS16475 3325030 3325323 + RNA-binding protein RNA binding protein found associated to pre-50S subunit of the ribosome%3B putative role in ribosome assembly%3B necessary for optimal growth but not cell viability gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16475 SG48_RS16480 SG48_3237 greA greA 3325479 3325955 - transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16480 SG48_RS16485 SG48_3238 SG48_RS16485 3326203 3327636 + D-alanyl-D-alanine carboxypeptidase penicillin binding protein 4%3B penicillin sensitive%3B catalyzes the formation of D-alanine from D-alanyl-D-alanine%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16485 SG48_RS16490 SG48_3239 obgE obgE 3327822 3328994 - GTPase CgtA ObgE%3B essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16490 SG48_RS16495 SG48_3240 SG48_RS16495 3329010 3329975 - transporter gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16495 SG48_RS16500 SG48_3241 rpmA rpmA 3330102 3330359 - 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16500 SG48_RS16505 SG48_3242 rplU rplU 3330380 3330691 - 50S ribosomal protein L21 gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16505 SG48_RS16510 SG48_3243 SG48_RS16510 3330950 3331921 + octaprenyl-diphosphate synthase gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16510 SG48_RS16515 SG48_3244 SG48_RS16515 3332149 3332427 + sugar fermentation stimulation protein B activator of maltose metabolism genes gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16515 SG48_RS16520 SG48_3245 SG48_RS16520 3332475 3333734 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16520 SG48_RS16525 SG48_3246 SG48_RS16525 3333789 3334043 - acid stress protein IbaG gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16525 SG48_RS16530 SG48_3247 SG48_RS16530 3334203 3334496 - phospholipid ABC transporter-binding protein gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16530 SG48_RS16535 SG48_3248 SG48_RS16535 3334496 3335131 - phospholipid-binding protein involved in maintaining outer membrane lipid asymmetry gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16535 SG48_RS16540 SG48_3249 SG48_RS16540 3335150 3335701 - outer membrane lipid asymmetry maintenance protein MlaD gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16540 SG48_RS16545 SG48_3250 SG48_RS16545 3335706 3336488 - phospholipid ABC transporter permease gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16545 SG48_RS16550 SG48_3251 SG48_RS16550 3336496 3337305 - phospholipid import ATP-binding protein ABC transporter maintaining outer membrane lipid asymmetry gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16550 SG48_RS16555 SG48_3252 SG48_RS16555 3337515 3338492 + hypothetical protein YrbG%3B inner membrane protein involved in cell envelope integrity%3B putative sodium ion/calcium ion exchanger%3B in E. coli it is non essential for cell viability%3B member of the YRBG family of cation/Ca2+ exchangers gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16555 SG48_RS16560 SG48_3253 SG48_RS16560 3338506 3339492 + arabinose 5-phosphate isomerase KdsD gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16560 SG48_RS16565 SG48_3254 SG48_RS16565 3339513 3340079 + 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC forms homotetramers%3B catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate%3B functions in lipopolysaccharide biosynthesis gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16565 SG48_RS16570 SG48_3255 SG48_RS16570 3340076 3340651 + LPS export ABC transporter periplasmic protein LptC gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16570 SG48_RS16575 SG48_3256 SG48_RS16575 3340620 3341177 + LPS export system protein LptA LptA%3B periplasmic binding protein part of a putative ABC superfamily of uptake transporters%3B interacts with LptB protein%2C the ATP binding component of the uptake system gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16575 SG48_RS16580 SG48_3257 SG48_RS16580 3341184 3341909 + LPS export ABC transporter ATP-binding protein gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16580 SG48_RS16585 SG48_3258 SG48_RS16585 3341957 3343390 + RNA polymerase sigma-54 factor sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism%3B the rhizobia often have 2 copies of this sigma factor%3B in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation%3B in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions%2C rpoN1 gene was regulated in response to oxygen gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16585 SG48_RS16590 SG48_3259 SG48_RS16590 3343413 3343700 + ribosome hibernation promoting factor YhbH%3B resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase%3B binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization)%3B seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16590 SG48_RS16595 SG48_3260 SG48_RS16595 3343818 3344309 + nitrogen regulatory protein involved in nitrogen metabolism%3B protein IIA is phosphorylated by enzyme I(Ntr) gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16595 SG48_RS16600 SG48_3261 SG48_RS16600 3344355 3345209 + glmZ(sRNA)-inactivating NTPase glucosamine-6-phosphate regulated%3B inactivates the glmS upregulator glmZ gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16600 SG48_RS16605 SG48_3262 SG48_RS16605 3345206 3345478 + phosphocarrier protein NPr gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16605 SG48_RS16610 SG48_3263 SG48_RS16610 3345692 3346324 + hypothetical protein gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16610 SG48_RS16615 SG48_3264 mtgA mtgA 3346321 3347049 - monofunctional biosynthetic peptidoglycan transglycosylase glycosyltransferase%3B polymerizes glycan strands in the peptidoglycan gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16615 SG48_RS16620 SG48_3265 SG48_RS16620 3347046 3347699 - enhancing lycopene biosynthesis protein 2 gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16620 SG48_RS16625 SG48_3267 SG48_RS16625 3347929 3350265 - PAS domain-containing two-component system sensor histidine kinase/response regulator sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon%3B hybrid sensory histidine kinase in two-component regulatory system with ArcA gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16625 SG48_RS16630 SG48_3268 SG48_RS16630 3350361 3351290 - radical SAM protein gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16630 SG48_RS16635 SG48_3269 gltB gltB 3351965 3356425 + glutamate synthase catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16635 SG48_RS16640 SG48_3270 SG48_RS16640 3356438 3357856 + glutamate synthase gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16640 SG48_RS16645 SG48_3271 SG48_RS16645 3358416 3359180 + glutamate synthase operon protein GltF gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16645 SG48_RS16650 SG48_3272 SG48_RS16650 3359352 3360026 + periplasmic chaperone protein member of the periplasmic pilus chaperone family of proteins gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16650 SG48_RS16655 SG48_3273 SG48_RS16655 3360047 3362428 + outer membrane fimbrial subunit usher protein gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16655 SG48_RS16660 SG48_RS16660 SG48_RS16660 3362425 3362793 + hypothetical protein gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16660 SG48_RS16665 SG48_3275 SG48_RS16665 3362942 3363922 - transposase gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16665 SG48_RS16670 SG48_RS16670 SG48_RS16670 3363921 3364169 + hypothetical protein gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16670 SG48_RS16675 SG48_3276 SG48_RS16675 3364166 3364882 + transcriptional regulator gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16675 SG48_RS16680 SG48_3277 SG48_RS16680 3365067 3366194 + DUF1016 domain-containing protein gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16680 SG48_RS16685 SG48_3278 SG48_RS16685 3366254 3366718 - DUF386 domain-containing protein gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16685 SG48_RS16690 SG48_3279 SG48_RS16690 3366715 3367590 - N-acetylmannosamine kinase catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16690 SG48_RS16695 SG48_3280 SG48_RS16695 3367587 3368276 - N-acetylmannosamine-6-P epimerase Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16695 SG48_RS16700 SG48_3281 SG48_RS16700 3368324 3369814 - sialic acid transporter gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16700 SG48_RS16705 SG48_3282 SG48_RS16705 3369923 3370816 - N-acetylneuraminate lyase catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16705 SG48_RS16710 SG48_3283 SG48_RS16710 3370938 3371729 - transcriptional regulator NanR Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16710 SG48_RS16715 SG48_3284 SG48_RS16715 3372109 3373476 + transporter YhcL%3B uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters%3B probable role in transport of carboxylates across the inner membrane from the periplasm%3B its encoding gene is not essential for growth and is probably cryptic gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16715 SG48_RS16720 SG48_3285 SG48_RS16720 3373519 3374016 - stringent starvation protein B gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16720 SG48_RS16725 SG48_3286 sspA sspA 3374022 3374660 - stringent starvation protein A transcriptional activator%3B required for activation of bacteriophage P1 late promoter%3B induced by starvation gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16725 SG48_RS16730 SG48_3287 SG48_RS16730 3375055 3375447 - 30S ribosomal protein S9 gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16730 SG48_RS16735 SG48_3288 SG48_RS16735 3375463 3375891 - 50S ribosomal protein L13 gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16735 SG48_RS16740 SG48_3289 SG48_RS16740 3376110 3377237 - cell division protein ZapE gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16740 SG48_RS16745 SG48_3290 SG48_RS16745 3377431 3377829 + hypothetical protein gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16745 SG48_RS16750 SG48_3291 SG48_RS16750 3377983 3379350 + periplasmic pH-dependent serine endoprotease DegQ gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16750 SG48_RS16755 SG48_3292 SG48_RS16755 3379440 3380507 + serine endoprotease DegS gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16755 SG48_RS16760 SG48_3293 SG48_RS16760 3380570 3381508 - malate dehydrogenase oxidizes malate to oxaloacetate gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16760 SG48_RS16765 SG48_3294 SG48_RS16765 3381943 3382413 + arginine repressor regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16765 SG48_RS16770 SG48_3295 SG48_RS16770 3382778 3383041 + membrane protein gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16770 SG48_RS16775 SG48_3296 SG48_RS16775 3383097 3383369 - barnase inhibitor gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16775 SG48_RS16780 SG48_3297 SG48_RS16780 3383461 3385428 - p-hydroxybenzoic acid efflux pump subunit AaeB with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16780 SG48_RS16785 SG48_3298 SG48_RS16785 3385434 3386366 - p-hydroxybenzoic acid efflux pump subunit AaeA with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid%2C 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16785 SG48_RS16790 SG48_3299 SG48_RS16790 3386374 3386577 - protein AaeX membrane protein AaeX%3B the gene is a member of the aaeXAB operon gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16790 SG48_RS16795 SG48_3300 SG48_RS16795 3386760 3387689 + HTH-type transcriptional activator AaeR for aaeXAB operon gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16795 SG48_RS16800 SG48_3301 tldD tldD 3387823 3389268 - protease TldD responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17%2C an exported protein that targets the essential topoisomerase II DNA gyrase%3B degrades the E. coli plasmid F-encoded CcdA gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16800 SG48_RS16805 SG48_3302 SG48_RS16805 3389698 3393498 - DUF3971 domain-containing protein gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16805 SG48_RS16810 SG48_3303 SG48_RS16810 3393566 3395035 - ribonuclease G involved in the processing of the 5'end of 16S rRNA gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16810 SG48_RS16815 SG48_3304 SG48_RS16815 3395025 3395618 - septum formation inhibitor Maf Maf%3B overexpression in Bacillus subtilis inhibits septation in the dividing cell gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16815 SG48_RS16820 SG48_3305 SG48_RS16820 3395627 3396115 - rod shape-determining protein MreD part of cell wall structural complex MreBCD%3B transmembrane component gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16820 SG48_RS16825 SG48_3306 SG48_RS16825 3396115 3397218 - cell shape-determining protein MreC in some organisms this protein is a transmembrane protein while in others it is periplasmic%3B involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16825 SG48_RS16830 SG48_3307 SG48_RS16830 3397284 3398327 - rod shape-determining protein MreB gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16830 SG48_RS16835 SG48_RS16835 SG48_RS16835 3398435 3398623 + hypothetical protein gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16835 SG48_RS16840 SG48_3308 SG48_RS16840 3398632 3400572 - RNase E specificity factor CsrD regulates the degradation of the small RNAs CsrB and CsrC%3B may function to targate RNase E to specific RNA molecules gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16840 SG48_RS16845 SG48_3309 SG48_RS16845 3400724 3401698 + acrylyl-CoA reductase AcuI gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16845 SG48_RS16850 SG48_RS16850 SG48_RS16850 3401756 3401857 - hypothetical protein gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16850 SG48_RS16855 SG48_RS16855 SG48_RS16855 3401984 3402103 + hypothetical protein gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16855 SG48_RS16860 SG48_RS16860 SG48_RS16860 3402107 3402271 + hypothetical protein gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16860 SG48_RS16865 SG48_3312 SG48_RS16865 3402676 3403146 + acetyl-CoA carboxylase biotin carboxyl carrier protein subunit composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex%2C the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16865 SG48_RS16870 SG48_3313 SG48_RS16870 3403157 3404506 + acetyl-CoA carboxylase biotin carboxylase subunit an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16870 SG48_RS16875 SG48_3314 SG48_RS16875 3404615 3404857 + DUF997 domain-containing protein gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16875 SG48_RS16880 SG48_3315 panF panF 3404847 3406298 + sodium/pantothenate symporter mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions%3B member of SSS family of sodium/solute symporters%3B the imported panthothenate is phosphorylated by panthothenate kinase gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16880 SG48_RS16885 SG48_3316 prmA prmA 3406310 3407191 + ribosomal protein L11 methyltransferase methylates ribosomal protein L11 at multiple amino acid positions%3B mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16885 SG48_RS16890 SG48_3317 SG48_RS16890 3407520 3408485 + tRNA-dihydrouridine synthase B gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16890 SG48_RS16895 SG48_3318 fis fis 3408511 3408807 + Fis family transcriptional regulator Stimulates excision of phage lambda%3B affects Mu development%3B acts as an activator of rRNA and iRNA transcription gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16895 SG48_RS16900 SG48_3319 SG48_RS16900 3408893 3409777 + DNA adenine methyltransferase YhdJ gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16900 SG48_RS16905 SG48_3320 SG48_RS16905 3409861 3410040 + transporter gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16905 SG48_RS16910 SG48_3321 SG48_RS16910 3410043 3410705 - acrEF/envCD operon repressor gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16910 SG48_RS16915 SG48_3322 SG48_RS16915 3411104 3412261 + MexX family efflux pump subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16915 SG48_RS16920 SG48_3323 SG48_RS16920 3412273 3415377 + multidrug efflux RND transporter permease subunit gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16920 SG48_RS16925 SG48_3324 SG48_RS16925 3415630 3415851 + membrane protein gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16925 SG48_RS16930 SG48_RS16930 SG48_RS16930 3416077 3416253 + hypothetical protein gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16930 SG48_RS16935 SG48_RS16935 SG48_RS16935 3416389 3417306 + amino acid ABC transporter substrate-binding protein gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16935 SG48_RS16940 SG48_3326 SG48_RS16940 3417374 3418555 + amino acid ABC transporter permease gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16940 SG48_RS16945 SG48_3327 SG48_RS16945 3418565 3419668 + amino acid ABC transporter permease gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16945 SG48_RS16950 SG48_3328 SG48_RS16950 3419676 3420434 + amino acid ABC transporter ATPase gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16950 SG48_RS16955 SG48_3329 SG48_RS16955 3420665 3420780 - 5S ribosomal RNA rRNA gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16955 SG48_RS16960 SG48_3330 SG48_RS16960 3420820 3420895 - tRNA-Thr tRNA gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16960 SG48_RS16965 SG48_3331 SG48_RS16965 3420910 3421025 - 5S ribosomal RNA rRNA gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16965 SG48_RS16970 SG48_3332 SG48_RS16970 3421103 3424032 - 23S ribosomal RNA rRNA gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16970 SG48_RS16975 SG48_3333 SG48_RS16975 3424198 3424273 - tRNA-Ala tRNA gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16975 SG48_RS16980 SG48_3334 SG48_RS16980 3424316 3424392 - tRNA-Ile tRNA gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16980 SG48_RS16985 SG48_3335 SG48_RS16985 3424449 3426004 - 16S ribosomal RNA rRNA gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16985 SG48_RS16990 SG48_3336 SG48_RS16990 3426476 3427030 + hypothetical protein gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16990 SG48_RS16995 SG48_3337 SG48_RS16995 3427006 3427263 - DUF1488 domain-containing protein gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS16995 SG48_RS17000 SG48_3338 SG48_RS17000 3427260 3428078 - shikimate dehydrogenase (NADP+) gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17000 SG48_RS17005 SG48_3339 SG48_RS17005 3428083 3428655 - threonylcarbamoyl-AMP synthase involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17005 SG48_RS17010 SG48_3340 SG48_RS17010 3428660 3429202 - ssDNA-binding protein%2C function unknown gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17010 SG48_RS17015 SG48_3341 SG48_RS17015 3429231 3429704 - protein Smg gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17015 SG48_RS17020 SG48_3342 SG48_RS17020 3429676 3430800 - protein smf gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17020 SG48_RS17025 SG48_3343 SG48_RS17025 3430930 3431439 + peptide deformylase gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17025 SG48_RS17030 SG48_3344 fmt fmt 3431454 3432401 + methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17030 SG48_RS17035 SG48_3345 SG48_RS17035 3432447 3433736 + ribosomal RNA small subunit methyltransferase B catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA%3B SAM-dependent methyltransferase gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17035 SG48_RS17040 SG48_3346 trkA trkA 3433758 3435134 + trk system potassium uptake protein trkA involved in potassium uptake%3B found to be peripherally associated with the inner membrane in Escherichia coli%3B contains an NAD-binding domain gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17040 SG48_RS17045 SG48_3347 mscL mscL 3435264 3435674 + large-conductance mechanosensitive channel forms homopentamer%3B channel that opens in response to pressure or hypoosmotic shock gene gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17045 SG48_RS17050 SG48_3348 SG48_RS17050 3435671 3435889 - ribosome-rescue factor A gene gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17050 SG48_RS17055 SG48_3349 zntR zntR 3435945 3436370 - transcriptional regulator mediates expression of the zinc export protein ZntA in response to high levels of zinc%3B member of MerR family of transcriptional regulators gene gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17055 SG48_RS17060 SG48_3350 SG48_RS17060 3436381 3436749 - DUF1992 domain-containing protein gene gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17060 SG48_RS17065 SG48_3351 rplQ rplQ 3436856 3437239 - 50S ribosomal protein L17 is a component of the macrolide binding site in the peptidyl transferase center gene gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17065 SG48_RS17070 SG48_3352 SG48_RS17070 3437280 3438269 - DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17070 SG48_RS17075 SG48_3353 SG48_RS17075 3438295 3438915 - 30S ribosomal protein S4 gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17075 SG48_RS17080 SG48_3354 SG48_RS17080 3438949 3439338 - 30S ribosomal protein S11 gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17080 SG48_RS17085 SG48_3355 SG48_RS17085 3439355 3439711 - 30S ribosomal protein S13 gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17085 SG48_RS17090 SG48_3356 SG48_RS17090 3439858 3439974 - 50S ribosomal protein L36 gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17090 SG48_RS17095 SG48_3357 secY secY 3440006 3441337 - protein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17095 SG48_RS17100 SG48_3358 SG48_RS17100 3441345 3441779 - 50S ribosomal protein L15 gene gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17100 SG48_RS17105 SG48_3359 rpmD rpmD 3441783 3441962 - 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17105 SG48_RS17110 SG48_3360 SG48_RS17110 3441966 3442469 - 30S ribosomal protein S5 gene gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17110 SG48_RS17115 SG48_3361 SG48_RS17115 3442484 3442837 - 50S ribosomal protein L18 gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17115 SG48_RS17120 SG48_3362 SG48_RS17120 3442847 3443380 - 50S ribosomal protein L6 gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17120 SG48_RS17125 SG48_3363 SG48_RS17125 3443393 3443785 - 30S ribosomal protein S8 gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17125 SG48_RS17130 SG48_3364 rpsN rpsN 3443819 3444124 - 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17130 SG48_RS17135 SG48_3365 SG48_RS17135 3444139 3444678 - 50S ribosomal protein L5 gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17135 SG48_RS17140 SG48_3366 rplX rplX 3444693 3445007 - 50S ribosomal protein L24 assembly initiator protein%3B binds to 5' end of 23S rRNA and nucleates assembly of the 50S%3B surrounds polypeptide exit tunnel gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17140 SG48_RS17145 SG48_3367 SG48_RS17145 3445018 3445389 - 50S ribosomal protein L14 gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17145 SG48_RS17150 SG48_3368 SG48_RS17150 3445554 3445808 - 30S ribosomal protein S17 gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17150 SG48_RS17155 SG48_3369 SG48_RS17155 3445808 3445999 - 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17155 SG48_RS17160 SG48_3370 SG48_RS17160 3445999 3446409 - 50S ribosomal protein L16 gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17160 SG48_RS17165 SG48_3371 SG48_RS17165 3446422 3447123 - 30S ribosomal protein S3 gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17165 SG48_RS17170 SG48_3372 SG48_RS17170 3447141 3447473 - 50S ribosomal protein L22 gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17170 SG48_RS17175 SG48_3373 SG48_RS17175 3447488 3447766 - 30S ribosomal protein S19 gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17175 SG48_RS17180 SG48_3374 SG48_RS17180 3447783 3448604 - 50S ribosomal protein L2 gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17180 SG48_RS17185 SG48_3375 rplW rplW 3448622 3448924 - 50S ribosomal protein L23 binds third domain of 23S rRNA and protein L29%3B part of exit tunnel gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17185 SG48_RS17190 SG48_3376 rplD rplD 3448921 3449526 - 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17190 SG48_RS17195 SG48_3377 SG48_RS17195 3449537 3450166 - 50S ribosomal protein L3 gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17195 SG48_RS17200 SG48_3378 rpsJ rpsJ 3450199 3450510 - 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17200 SG48_RS17205 SG48_3379 SG48_RS17205 3450748 3451167 - hypothetical protein involved in type II protein secretion gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17205 SG48_RS17210 SG48_3380 SG48_RS17210 3451169 3452638 - general secretory pathway protein gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17210 SG48_RS17215 SG48_3381 SG48_RS17215 3452818 3453633 + type II secretion system protein GspC gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17215 SG48_RS17220 SG48_3382 SG48_RS17220 3453617 3455569 + type II secretion system protein GspD gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17220 SG48_RS17225 SG48_3383 SG48_RS17225 3455579 3457060 + type II secretion system protein GspE gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17225 SG48_RS17230 SG48_3384 SG48_RS17230 3457057 3458253 + type II secretion system protein GspF gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17230 SG48_RS17235 SG48_3385 SG48_RS17235 3458263 3458700 + type II secretion system protein GspG gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17235 SG48_RS17240 SG48_3386 SG48_RS17240 3458708 3459217 + type II secretion system protein GspH gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17240 SG48_RS17245 SG48_3387 SG48_RS17245 3459214 3459591 + type II secretion system protein GspI gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17245 SG48_RS17250 SG48_3388 SG48_RS17250 3459584 3460171 + general secretion pathway protein gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17250 SG48_RS17255 SG48_3389 SG48_RS17255 3460164 3461147 + general secretory pathway protein gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17255 SG48_RS17260 SG48_3390 SG48_RS17260 3461162 3462325 + type II secretion system protein GspL gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17260 SG48_RS17265 SG48_3391 SG48_RS17265 3462322 3462783 + general secretion pathway protein GspM gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17265 SG48_RS17270 SG48_3392 SG48_RS17270 3462783 3463460 + type 4 prepilin-like proteins leader peptide-processing enzyme gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17270 SG48_RS17275 SG48_3393 SG48_RS17275 3463489 3463965 - bacterioferritin iron storage protein gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17275 SG48_RS17280 SG48_3394 SG48_RS17280 3464037 3464231 - bacterioferritin-associated ferredoxin gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17280 SG48_RS17285 SG48_3395 SG48_RS17285 3464400 3467093 - bifunctional chitinase/lysozyme gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17285 SG48_RS17290 SG48_3396 tuf tuf 3467385 3468569 - translation elongation factor EF-Tu 1 EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17290 SG48_RS17295 SG48_3397 fusA fusA 3468640 3470754 - elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17295 SG48_RS17300 SG48_3398 SG48_RS17300 3470782 3471321 - 30S ribosomal protein S7 gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17300 SG48_RS17305 SG48_3399 SG48_RS17305 3471418 3471792 - 30S ribosomal protein S12 gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17305 SG48_RS17310 SG48_3400 SG48_RS17310 3471918 3472205 - protein TusB in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17310 SG48_RS17315 SG48_3401 SG48_RS17315 3472213 3472572 - protein TusC in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur transfer that results in thiouridation to U34 position in some tRNAs gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17315 SG48_RS17320 SG48_3402 SG48_RS17320 3472572 3472958 - sulfurtransferase TusD in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17320 SG48_RS17325 SG48_3403 SG48_RS17325 3472958 3473680 - transcriptional regulator gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17325 SG48_RS17330 SG48_3404 SG48_RS17330 3473847 3474659 - FKBP-type peptidyl-prolyl cis-trans isomerase rotamase gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17330 SG48_RS17335 SG48_3405 SG48_RS17335 3474880 3475098 + protein SlyX required for phi X174 lysis gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17335 SG48_RS17340 SG48_3406 SG48_RS17340 3475147 3475737 - FKBP-type peptidyl-prolyl cis-trans isomerase rotamase gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17340 SG48_RS17345 SG48_3407 SG48_RS17345 3475832 3476032 - hypothetical protein gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17345 SG48_RS17350 SG48_3408 SG48_RS17350 3476042 3477847 - glutathione-regulated potassium-efflux system protein KefB involved in potassium efflux gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17350 SG48_RS17355 SG48_3409 SG48_RS17355 3477847 3478398 - potassium transporter required for KefB activity gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17355 SG48_RS17360 SG48_3410 SG48_RS17360 3478529 3480442 + ABC transporter ATP-binding protein gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17360 SG48_RS17365 SG48_3411 SG48_RS17365 3480442 3481464 + UPF0017 family hydrolase gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17365 SG48_RS17370 SG48_3412 SG48_RS17370 3481458 3481676 + hypothetical protein gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17370 SG48_RS17375 SG48_3413 SG48_RS17375 3481730 3482599 + phosphoribulokinase gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17375 SG48_RS17380 SG48_3414 SG48_RS17380 3482654 3483058 - hypothetical protein gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17380 SG48_RS17385 SG48_RS17385 SG48_RS17385 3483138 3483353 + hypothetical protein gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17385 SG48_RS17390 SG48_3415 SG48_RS17390 3483360 3483992 + cAMP-activated global transcriptional regulator CRP cAMP receptor protein%3B complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17390 SG48_RS17395 SG48_3416 SG48_RS17395 3484043 3486133 + membrane protein gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17395 SG48_RS17400 SG48_3417 argD argD 3486200 3487420 - acetylornithine aminotransferase DapATase%3B bifunctional enzyme that functions in arginine and lysine biosynthetic pathways%3B catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2%2C6-diaminoheptanedioate gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17400 SG48_RS17405 SG48_3418 SG48_RS17405 3487506 3488069 - aminodeoxychorismate synthase TrpG%3B with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine%3B TrpG provides the glutamine amidotransferase activity gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17405 SG48_RS17410 SG48_3419 SG48_RS17410 3488101 3488703 - adenosine monophosphate-protein transferase gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17410 SG48_RS17415 SG48_3420 SG48_RS17415 3488693 3488860 - antitoxin gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17415 SG48_RS17420 SG48_3421 SG48_RS17420 3488965 3489537 - peptidyl-prolyl cis-trans isomerase gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17420 SG48_RS17425 SG48_3422 SG48_RS17425 3489808 3490989 + protein TsgA gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17425 SG48_RS17430 SG48_3423 SG48_RS17430 3491251 3493794 + nitrite reductase (NADH) large subunit gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17430 SG48_RS17435 SG48_3424 nirD nirD 3493791 3494117 + nitrite reductase (NADH) small subunit involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+%3B bounds to NirB%2C the cytoplasmic subunit%2C whose expression is induced at high nitrate concentrations gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17435 SG48_RS17440 SG48_3425 SG48_RS17440 3494243 3495049 + nitrite transporter NirC member of the FNT family of formate and nitrite transporters gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17440 SG48_RS17445 SG48_3426 cysG cysG 3495068 3496441 + siroheme synthase multifunction enzyme consisting of uroporphyrin-III C-methyltransferase%2C precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase%3B catalyzes the methylation of uroporphyrinogen III to form precorrin-2%2C then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17445 SG48_RS17450 SG48_3427 SG48_RS17450 3496688 3496855 + lipoprotein gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17450 SG48_RS17455 SG48_3428 frlA frlA 3497150 3498487 + fructoselysine transporter inner membrane protein possibly involved in fructoselysine transport%3B member of the flr operon gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17455 SG48_RS17460 SG48_3429 frlB frlB 3498508 3499530 + fructoselysine 6-phosphate deglycase catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17460 SG48_RS17465 SG48_3430 SG48_RS17465 3499580 3500410 + protein FrlC YhfOP%3B YhfP%3B YhfO%3B FrlC%3B catalyzes the interconversion of fructoselysine and psicoselysine gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17465 SG48_RS17470 SG48_3431 SG48_RS17470 3500407 3501192 + fructoselysine kinase gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17470 SG48_RS17475 SG48_3432 SG48_RS17475 3501292 3502023 + transcriptional regulator may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM%2C yhfN%2C yhfO%2C yhfP%2C yhfQ%2C and yhfR genes gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17475 SG48_RS17480 SG48_3433 SG48_RS17480 3502175 3503260 - FNR-regulated pyridoxal phosphate-dependent aminotransferase gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17480 SG48_RS17485 SG48_3434 SG48_RS17485 3503272 3504576 - hypothetical protein gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17485 SG48_RS17490 SG48_3435 SG48_RS17490 3504588 3504941 - DUF2620 domain-containing protein gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17490 SG48_RS17495 SG48_3436 SG48_RS17495 3504952 3505830 - phosphotriesterase homology protein phosphotriesterase homology protein%3B PhP%3B YhfV%3B member of a family of proteins related to phosphotriesterase (PTE) gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17495 SG48_RS17500 SG48_3437 SG48_RS17500 3505827 3507053 - phosphopentomutase-related metalloenzyme superfamily protein gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17500 SG48_RS17505 SG48_3438 SG48_RS17505 3507053 3508216 - pyridoxal 5''-phosphate binding protein gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17505 SG48_RS17510 SG48_3439 SG48_RS17510 3508300 3508662 - PRD domain protein gene gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17510 SG48_RS17515 SG48_3440 SG48_RS17515 3508679 3509584 - transcriptional regulator gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17515 SG48_RS17520 SG48_3441 SG48_RS17520 3509874 3510878 - tryptophan--tRNA ligase gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17520 SG48_RS17525 SG48_3442 SG48_RS17525 3510871 3511629 - phosphoglycolate phosphatase catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17525 SG48_RS17530 SG48_3443 SG48_RS17530 3511622 3512299 - ribulose-phosphate 3-epimerase gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17530 SG48_RS17535 SG48_3444 SG48_RS17535 3512317 3513153 - DNA adenine methylase gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17535 SG48_RS17540 SG48_3445 SG48_RS17540 3513260 3514546 - protein DamX binds the septal ring gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17540 SG48_RS17545 SG48_3446 aroB aroB 3514638 3515726 - 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17545 SG48_RS17550 SG48_3447 aroK aroK 3515783 3516304 - shikimate kinase type I enzyme similar to type II but differentially regulated%3B major shikimate kinase in fully repressed cells%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17550 SG48_RS17555 SG48_3448 hofQ hofQ 3516705 3517865 - porin outer membrane porin probably involved in uptake of extracellular double-stranded DNA%3B similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17555 SG48_RS17560 SG48_3449 SG48_RS17560 3517855 3518259 - DNA catabolic protein gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17560 SG48_RS17565 SG48_3450 SG48_RS17565 3518249 3518689 - DNA catabolic protein gene gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17565 SG48_RS17570 SG48_3451 SG48_RS17570 3518673 3519212 - DNA utilization protein HofN gene gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17570 SG48_RS17575 SG48_3452 SG48_RS17575 3519212 3519991 - DNA catabolic pilus assembly protein gene gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17575 SG48_RS17580 SG48_3453 mrcA mrcA 3520111 3522663 + penicillin-binding protein 1A bifunctional murein transglycosylase/murein transpeptidase%3B penicillin-binding protein 1A%3B involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation%3B penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits gene gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17580 SG48_RS17585 SG48_3454 nudE nudE 3522829 3523389 - ADP compounds hydrolase NudE ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17585 SG48_RS17590 SG48_3455 SG48_RS17590 3523709 3525844 + RcsCDB-response attenuator%2C inner membrane protein gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17590 SG48_RS17595 SG48_3456 SG48_RS17595 3525909 3526577 + GMP/IMP nucleotidase YrfG gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17595 SG48_RS17600 SG48_3457 SG48_RS17600 3526588 3526989 + heat-shock protein 15 gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17600 SG48_RS17605 SG48_3458 hslO hslO 3527014 3527892 + heat-shock protein Hsp33 becomes active under oxidative stress%3B four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive%3B oxidative stress results in oxidized cysteines%2C release of zinc%2C and binding of Hsp33 to aggregation-prone proteins%3B forms dimers and higher order oligomers gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17605 SG48_RS17610 SG48_3459 SG48_RS17610 3527955 3529679 - DUF4153 domain-containing protein gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17610 SG48_RS17615 SG48_RS17615 SG48_RS17615 3529755 3529886 - hypothetical protein gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17615 SG48_RS17620 SG48_3460 SG48_RS17620 3530058 3531680 + phosphoenolpyruvate carboxykinase [ATP] PEP carboxykinase%3B PEP carboxylase%3B PEPCK%3B catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17620 SG48_RS17625 SG48_3461 envZ envZ 3531756 3533108 - two-component system sensor histidine kinase membrane-localized osmosensor%3B histidine kinase%3B in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17625 SG48_RS17630 SG48_3462 ompR ompR 3533105 3533824 - two-component system response regulator part of two-component system EnvZ/OmpR%3B regulates transcription of outer membrane porin genes ompC/F%3B under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR%3B the result is increased expression of ompC and repression of ompF%3B also functions in regulation of other genes%3B forms dimers upon phosphorylation gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17630 SG48_RS17635 SG48_3463 greB greB 3534052 3534528 + transcription elongation factor GreB necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17635 SG48_RS17640 SG48_3464 SG48_RS17640 3534625 3536946 + hypothetical protein gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17640 SG48_RS17645 SG48_3465 feoA feoA 3537403 3537630 + ferrous iron transporter A gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17645 SG48_RS17650 SG48_3466 feoB feoB 3537647 3539968 + ferrous iron transporter B cytoplasmic membrane ferrous uptake system permease%3B mutations disrupt the ability of Escherichia coli to take up ferrous iron%3B GTP-binding protein which requires GTP for efficient iron(II) uptake gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17650 SG48_RS17655 SG48_3467 SG48_RS17655 3539968 3540204 + ferrous iron transporter C regulatory protein that controls transcription of feoABC genes gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17655 SG48_RS17660 SG48_3468 SG48_RS17660 3540407 3541285 + transposase gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17660 SG48_RS17665 SG48_3469 SG48_RS17665 3541314 3542084 - pimeloyl-[acyl-carrier protein] methyl ester esterase Shows carboxylesterase activity with a preference for short chain fatty acid esters%3B involved in pimeloyl-CoA synthesis gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17665 SG48_RS17670 SG48_3470 SG48_RS17670 3542122 3542805 + protein GntX required for utilization of DNA as the sole source of carbon and energy gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17670 SG48_RS17675 SG48_3471 SG48_RS17675 3542864 3543439 + fe/S biogenesis protein nfuA cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17675 SG48_RS17680 SG48_3472 SG48_RS17680 3543799 3545115 + gluconate transporter gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17680 SG48_RS17685 SG48_3473 malQ malQ 3545226 3547310 - 4-alpha-glucanotransferase amylomaltase%3B acts to release glucose from maltodextrins gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17685 SG48_RS17690 SG48_3474 SG48_RS17690 3547320 3549713 - maltodextrin phosphorylase gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17690 SG48_RS17695 SG48_3475 SG48_RS17695 3550325 3553030 + transcriptional regulator Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17695 SG48_RS17700 SG48_3476 SG48_RS17700 3553073 3554089 - RNA 3'-terminal phosphate cyclase catalyzes the conversion of terminal3'-phosphate of RNA to the 2'%2C3'-cyclicphosphodiester gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17700 SG48_RS17705 SG48_3477 SG48_RS17705 3554093 3555319 - RNA-splicing ligase RtcB gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17705 SG48_RS17710 SG48_3478 SG48_RS17710 3555508 3557106 + transcriptional regulator sigma 54-dependent%3B regulates genes involved in forming a 2'%2C3'-cyclic phosphodiester on RNA gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17710 SG48_RS17715 SG48_3479 SG48_RS17715 3557088 3557846 - glycerol-3-phosphate regulon repressor represses the glpD%2C glpFK%2C glpTQ%2C and glpACB operons involved in glycerol-3-phosphate metabolism gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17715 SG48_RS17720 SG48_3480 SG48_RS17720 3557863 3558693 - rhomboid protease GlpG protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17720 SG48_RS17725 SG48_3481 glpE glpE 3558738 3559064 - thiosulfate sulfurtransferase GlpE belongs to rhodanese family%3B thiosulfate thiotransferase%3B in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency%3B contains an active site cysteine gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17725 SG48_RS17730 SG48_3482 glpD glpD 3559254 3560759 + aerobic glycerol-3-phosphate dehydrogenase in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions%3B anaerobic expression is repressed by the arcAB system%3B converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8%3B associates with the cytoplasmic membrane gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17730 SG48_RS17735 SG48_RS17735 SG48_RS17735 3560965 3561156 - membrane protein gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17735 SG48_RS17740 SG48_3484 SG48_RS17740 3561375 3563822 - glycogen phosphorylase gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17740 SG48_RS17745 SG48_3485 glgA glgA 3563841 3565274 - glycogen synthase catalyzes the formation of alpha-1%2C4-glucan chains from ADP-glucose gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17745 SG48_RS17750 SG48_3486 glgC glgC 3565274 3566569 - glucose-1-phosphate adenylyltransferase catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17750 SG48_RS17755 SG48_3487 SG48_RS17755 3566587 3568560 - glycogen debranching protein catalyzes the hydrolysis of the alpha-1%2C6-glucosidic linkages in partially depolymerized glycogen gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17755 SG48_RS17760 SG48_3488 SG48_RS17760 3568557 3570743 - 1%2C4-alpha-glucan-branching protein gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17760 SG48_RS17765 SG48_3489 SG48_RS17765 3571016 3572119 - aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17765 SG48_RS17770 SG48_3490 SG48_RS17770 3572312 3572905 + membrane protein gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17770 SG48_RS17775 SG48_3491 SG48_RS17775 3572962 3574302 - low-affinity gluconate transporter gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17775 SG48_RS17780 SG48_3492 gntK gntK 3574306 3574833 - thermoresistant gluconokinase thermoresistant%3B catalyzes the formation of 6-phospho-D-gluconate from gluconate gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17780 SG48_RS17785 SG48_3493 SG48_RS17785 3574972 3575967 - GntR family transcriptional regulator gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17785 SG48_RS17790 SG48_3494 SG48_RS17790 3576191 3576886 - quercetin 2%2C3-dioxygenase gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17790 SG48_RS17795 SG48_3495 SG48_RS17795 3577009 3578046 - oxidoreductase gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17795 SG48_RS17800 SG48_3497 SG48_RS17800 3578379 3578867 + aminoacyl nucleotide detoxifying acetyltransferase YhhY%3B regulated by the fur regulator%3B unknown function gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17800 SG48_RS17805 SG48_3498 SG48_RS17805 3579104 3580282 + colicin gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17805 SG48_RS17810 SG48_RS17810 SG48_RS17810 3580279 3580695 + hypothetical protein gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17810 SG48_RS17815 SG48_3501 SG48_RS17815 3580918 3581421 + transposase gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17815 SG48_RS17820 SG48_3502 SG48_RS17820 3582000 3582284 + heat-shock protein gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17820 SG48_RS17825 SG48_3503 ggt ggt 3582322 3584064 - gamma-glutamyltranspeptidase periplasmic enzyme%3B post-translationally processed into two subunits which are required for wild-type enzyme activity%3B cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17825 SG48_RS17830 SG48_3504 SG48_RS17830 3584184 3584624 + DUF2756 domain-containing protein gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17830 SG48_RS17835 SG48_3505 ugpQ ugpQ 3584611 3585354 - glycerophosphoryl diester phosphodiesterase hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol%3B induced when cells are starved for inorganic phosphate gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17835 SG48_RS17840 SG48_3506 ugpC ugpC 3585351 3586421 - sn-glycerol-3-phosphate import ATP-binding protein UgpC part of the UgpABCE glycerol-3-phosphate uptake system gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17840 SG48_RS17845 SG48_3507 SG48_RS17845 3586423 3587268 - sn-glycerol 3-phosphate ABC transporter permease with UgpABC is involved in uptake of glycerol-3-phosphate gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17845 SG48_RS17850 SG48_3508 SG48_RS17850 3587265 3588152 - sn-glycerol 3-phosphate ABC transporter permease with UgpEC is involved in the uptake of glycerol-3-phosphate gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17850 SG48_RS17855 SG48_3509 SG48_RS17855 3588250 3589566 - sn-glycerol-3-phosphate-binding periplasmic protein UgpB with UgpACE is involved in the uptake of glycerol-3-phosphate gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17855 SG48_RS17860 SG48_RS17860 SG48_RS17860 3589801 3589929 - hypothetical protein gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17860 SG48_RS17865 SG48_3510 livF livF 3589965 3590678 - branched-chain amino acid ABC transporter ATP-binding protein with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17865 SG48_RS17870 SG48_3511 livG livG 3590680 3591447 - branched-chain amino acid ABC transporter ATP-binding protein Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17870 SG48_RS17875 SG48_3512 livM livM 3591444 3592721 - branched-chain amino acid ABC transporter permease Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17875 SG48_RS17880 SG48_3513 SG48_RS17880 3592718 3593644 - branched-chain amino acid ABC transporter permease LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter gene gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17880 SG48_RS17885 SG48_3514 SG48_RS17885 3593692 3594801 - leucine-specific-binding protein with LivFGHM is involved in the high affinity leucine transport gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17885 SG48_RS17890 SG48_3515 SG48_RS17890 3595225 3595608 + pantothenate synthesis PanD autocleavage accelerator gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17890 SG48_RS17895 SG48_RS17895 SG48_RS17895 3595618 3595740 + hypothetical protein gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17895 SG48_RS17900 SG48_3516 SG48_RS17900 3595796 3596914 - amino acid ABC transporter substrate-binding protein with LivFGHM is involved in the high affinity leucine transport gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17900 SG48_RS17905 SG48_3517 SG48_RS17905 3597170 3598024 - RNA polymerase sigma factor RpoH binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17905 SG48_RS17910 SG48_3518 ftsX ftsX 3598269 3599327 - cell division protein FtsX ABC transporter%2C membrane protein gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17910 SG48_RS17915 SG48_3519 SG48_RS17915 3599320 3599988 - cell division ATP-binding protein FtsE ATP-binding protein of an ATP-binding cassette transporter%3B when bound to FtsX%2C FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17915 SG48_RS17920 SG48_3520 SG48_RS17920 3599991 3601484 - signal recognition particle receptor FtsY cell division protein%3B signal recognition protein receptor%3B functions in the targeting and insertion of membrane proteins gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17920 SG48_RS17925 SG48_3521 rsmD rsmD 3601634 3602230 + ribosomal RNA small subunit methyltransferase D catalyzes the methylation of 16S rRNA at position G966 gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17925 SG48_RS17930 SG48_3522 SG48_RS17930 3602220 3602489 + DUF1145 domain-containing protein gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17930 SG48_RS17935 SG48_3523 SG48_RS17935 3602492 3602851 - DUF2500 domain-containing protein gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17935 SG48_RS17940 SG48_3524 SG48_RS17940 3602992 3603618 + membrane protein gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17940 SG48_RS17945 SG48_3525 zntA zntA 3603692 3605890 + cadmium-transporting ATPase P-type ATPase involved in the export of lead%2C cadmium%2C zinc and mercury gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17945 SG48_RS17950 SG48_3526 SG48_RS17950 3605992 3606237 - sulfurtransferase TusA TusA%3B transfers sulfur to TusBCD complex%3B involved in thiouridation of U34 position of some tRNAs gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17950 SG48_RS17955 SG48_3527 SG48_RS17955 3606458 3607123 + hypothetical protein gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17955 SG48_RS17960 SG48_3528 SG48_RS17960 3607196 3607753 + protein DcrB gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17960 SG48_RS17965 SG48_3529 SG48_RS17965 3607757 3608974 - arabinose efflux transporter gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17965 SG48_RS17970 SG48_3530 SG48_RS17970 3609106 3610155 + pheromone autoinducer 2 transporter gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17970 SG48_RS17975 SG48_3531 SG48_RS17975 3610210 3610797 + 4'-phosphopantetheinyl transferase gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17975 SG48_RS17980 SG48_3532 SG48_RS17980 3610908 3612482 + nickel-binding periplasmic protein gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17980 SG48_RS17985 SG48_3533 SG48_RS17985 3612482 3613426 + nickel ABC transporter permease with NikACDE is involved in nickel transport into the cell gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17985 SG48_RS17990 SG48_3534 nikC nikC 3613423 3614256 + nickel ABC transporter permease with NikABDE is involved in nickel transport into the cell gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17990 SG48_RS17995 SG48_3535 nikD nikD 3614256 3615020 + nickel import ATP-binding protein NikD with NikABCE is involved in nickel transport into the cell gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS17995 SG48_RS18000 SG48_3536 nikE nikE 3615017 3615823 + nickel import ATP-binding protein NikE with NikABCD is involved with nickel transport into the cell gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18000 SG48_RS18005 SG48_3537 SG48_RS18005 3615829 3616230 + nickel-responsive regulator Inhibits transcription at high concentrations of nickel gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18005 SG48_RS18010 SG48_3538 SG48_RS18010 3616433 3620668 + RHS element protein gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18010 SG48_RS18015 SG48_3539 SG48_RS18015 3620640 3621023 + hypothetical protein gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18015 SG48_RS18020 SG48_RS18020 SG48_RS18020 3621128 3621478 + lyase gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18020 SG48_RS18025 SG48_3541 SG48_RS18025 3621619 3622755 + H repeat-associated protein YhhI gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18025 SG48_RS18030 SG48_3542 SG48_RS18030 3622920 3624044 - inner membrane transport permease YhhJ gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18030 SG48_RS18035 SG48_3543 SG48_RS18035 3624044 3626779 - ribosome-associated ATPase gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18035 SG48_RS18040 SG48_3544 SG48_RS18040 3626776 3627843 - membrane fusion protein (MFP) of efflux pump gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18040 SG48_RS18045 SG48_3545 SG48_RS18045 3628209 3629831 - DUF4049 domain-containing protein gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18045 SG48_RS18050 SG48_RS18050 SG48_RS18050 3630093 3631699 - hypothetical protein gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18050 SG48_RS18055 SG48_RS18055 SG48_RS18055 3631686 3631889 - hypothetical protein gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18055 SG48_RS18060 SG48_RS18060 SG48_RS18060 3632012 3632110 - hypothetical protein gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18060 SG48_RS18065 SG48_3547 SG48_RS18065 3632127 3633134 + membrane protein gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18065 SG48_RS18070 SG48_3548 SG48_RS18070 3633449 3634651 - oxidoreductase gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18070 SG48_RS18075 SG48_3549 SG48_RS18075 3634883 3636382 + Low-affinity inorganic phosphate transporter 1 involved in the transport of inorganic phosphate gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18075 SG48_RS18080 SG48_3550 SG48_RS18080 3636626 3636961 - universal stress protein B ppGpp-dependent%2C membrane associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18080 SG48_RS18085 SG48_3551 SG48_RS18085 3637352 3637786 + universal stress protein A involved in resistance to DNA-damaging agents gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18085 SG48_RS18090 SG48_3552 tppB tppB 3638103 3639572 + dipeptide and tripeptide permease B mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium%3B member of proton-dependent oligopeptide transport (POT) system family%3B in Escherichia coli this gene is regulated by OmpR although not via osmoregulation gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18090 SG48_RS18095 SG48_3553 SG48_RS18095 3639621 3640373 - ribosomal RNA small subunit methyltransferase J predicted SAM-dependent methyltransferase gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18095 SG48_RS18100 SG48_3554 SG48_RS18100 3640381 3642423 - oligopeptidase A gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18100 SG48_RS18105 SG48_3555 SG48_RS18105 3642626 3643468 + ribosomal RNA large subunit methyltransferase J gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18105 SG48_RS18110 SG48_3556 SG48_RS18110 3643540 3644892 + glutathione reductase catalyzes the reduction of 2 glutathione to glutathione disulfide%3B maintains high levels of reduced glutathione in the cytosol%3B involved in redox regulation and oxidative defense gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18110 SG48_RS18115 SG48_3557 SG48_RS18115 3644946 3645062 - hypothetical protein gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18115 SG48_RS18120 SG48_RS18120 SG48_RS18120 3645057 3645230 + hypothetical protein gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18120 SG48_RS18125 SG48_3558 SG48_RS18125 3645769 3646122 + arsenical resistance operon repressor regulates the expression of of the arsRBC involved in resistance to arsenic gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18125 SG48_RS18130 SG48_3559 SG48_RS18130 3646176 3647465 + arsenical pump membrane protein gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18130 SG48_RS18135 SG48_3560 SG48_RS18135 3647478 3647903 + arsenate reductase gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18135 SG48_RS18140 SG48_RS18140 SG48_RS18140 3648532 3649314 + hypothetical protein gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18140 SG48_RS18145 SG48_3562 SG48_RS18145 3649423 3650403 - transposase gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18145 SG48_RS18150 SG48_RS18150 SG48_RS18150 3650469 3650954 + hypothetical protein gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18150 SG48_RS18155 SG48_3563 SG48_RS18155 3651202 3651768 + outer membrane protein slp gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18155 SG48_RS18160 SG48_3564 SG48_RS18160 3651924 3652454 + transcriptional regulator gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18160 SG48_RS18165 SG48_3565 SG48_RS18165 3652496 3653143 - magnesium transporter ATPase gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18165 SG48_RS18170 SG48_3566 hdeB hdeB 3653207 3653533 - acid stress chaperone HdeB gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18170 SG48_RS18175 SG48_3567 SG48_RS18175 3653649 3653981 - acid stress chaperone HdeA inactive form gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18175 SG48_RS18180 SG48_3568 SG48_RS18180 3654236 3654808 + protein HdeD gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18180 SG48_RS18185 SG48_3570 SG48_RS18185 3655607 3656134 + transcriptional regulator GadE gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18185 SG48_RS18190 SG48_RS18190 SG48_RS18190 3656135 3656413 - hypothetical protein gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18190 SG48_RS18195 SG48_3571 SG48_RS18195 3656473 3657630 + multidrug resistance protein MdtE gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18195 SG48_RS18200 SG48_3572 SG48_RS18200 3657655 3660768 + multidrug efflux RND transporter permease subunit gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18200 SG48_RS18205 SG48_3573 SG48_RS18205 3661131 3661859 - transcriptional regulator gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18205 SG48_RS18210 SG48_3575 SG48_RS18210 3662227 3663051 - transcriptional regulator regulates genes in response to acid and/or during stationary phase gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18210 SG48_RS18215 SG48_3576 SG48_RS18215 3663421 3664821 - glutamate decarboxylase alpha gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18215 SG48_RS18220 SG48_3577 SG48_RS18220 3665032 3666429 - cytochrome c peroxidase gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18220 SG48_RS18225 SG48_3578 treF treF 3666833 3668482 + trehalase cytoplasmic%3B catalyzes the hydrolysis of trehalose to glucose gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18225 SG48_RS18230 SG48_3579 SG48_RS18230 3668533 3669135 - LuxR family transcriptional regulator gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18230 SG48_RS18235 SG48_3580 SG48_RS18235 3669655 3670554 + LysR family transcriptional regulator gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18235 SG48_RS18240 SG48_3581 SG48_RS18240 3670603 3671616 + hypothetical protein gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18240 SG48_RS18245 SG48_3582 SG48_RS18245 3672027 3673349 + metabolite transporter gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18245 SG48_RS18250 SG48_3583 SG48_RS18250 3673531 3675591 - hypothetical protein gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18250 SG48_RS18255 SG48_3584 SG48_RS18255 3675661 3676428 - cyclic di-GMP phosphodiesterase YhjH in Escherichia coli this protein is involved in flagellar function gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18255 SG48_RS18260 SG48_RS18260 SG48_RS18260 3676382 3676576 + hypothetical protein gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18260 SG48_RS18265 SG48_3585 SG48_RS18265 3676660 3677589 + 2-dehydro-3-deoxygluconokinase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18265 SG48_RS18270 SG48_3586 SG48_RS18270 3677685 3679181 - hypothetical protein gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18270 SG48_RS18275 SG48_3587 SG48_RS18275 3679402 3680688 - C4-dicarboxylate ABC transporter involved in the transport of C4-dicarboxylates across the membrane gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18275 SG48_RS18280 SG48_3588 SG48_RS18280 3680871 3682826 - biofilm formation regulator HmsP HmsP in Yersinia pestis plays a role in invasion of epithelial cells%3B the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation%3B inner membrane protein gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18280 SG48_RS18285 SG48_3589 SG48_RS18285 3682941 3686414 - cellulose synthase operon protein C cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium%3B the cellulose biosynthesis genes bcsA%2C bcsB%2C bcsZ and bcsC are constitutively transcribed%2C however%2C cellulose synthesis is dependent on the expression of adrA gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18285 SG48_RS18290 SG48_3590 SG48_RS18290 3686396 3687502 - endoglucanase catalyzes the hydrolysis of 1%2C4-beta-D-glucosidic linkages in cellulose%2C lichenin and cereal beta-D-glucans gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18290 SG48_RS18295 SG48_3591 SG48_RS18295 3687509 3689848 - cyclic di-GMP-binding protein binds the cellulose synthase activator%2C bis-(3'-5') cyclic diguanylic acid (c-di-GMP) gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18295 SG48_RS18300 SG48_3592 bcsA bcsA 3689859 3692477 - cellulose synthase catalytic subunit [UDP-forming] polymerizes uridine 5'-diphosphate glucose to cellulose%3B acts with BcsB%2C BcsZ and BcsC in cellulose biosynthesis gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18300 SG48_RS18305 SG48_RS18305 SG48_RS18305 3692474 3693145 - cell division protein gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18305 SG48_RS18310 SG48_3594 SG48_RS18310 3693238 3693426 - hypothetical protein gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18310 SG48_RS18315 SG48_3595 SG48_RS18315 3693711 3695270 + cellulose biosynthesis protein BcsE required for cellulose biosynthesis gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18315 SG48_RS18320 SG48_3596 SG48_RS18320 3695267 3695458 + protein BcsF gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18320 SG48_RS18325 SG48_3597 SG48_RS18325 3695455 3697134 + protein BcsG gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18325 SG48_RS18330 SG48_3598 SG48_RS18330 3697221 3697328 - small toxic polypeptide LdrD gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18330 SG48_RS18335 SG48_RS18335 SG48_RS18335 3697493 3697654 - hypothetical protein gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18335 SG48_RS18340 SG48_3600 SG48_RS18340 3697804 3699075 + transporter gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18340 SG48_RS18345 SG48_3601 dppF dppF 3699105 3700109 - dipeptide transport ATP-binding protein DppF Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18345 SG48_RS18350 SG48_3602 dppD dppD 3700106 3701089 - dipeptide transport ATP-binding protein DppD DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18350 SG48_RS18355 SG48_3603 SG48_RS18355 3701100 3702002 - peptide ABC transporter permease gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18355 SG48_RS18360 SG48_3604 SG48_RS18360 3702012 3703031 - peptide ABC transporter permease gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18360 SG48_RS18365 SG48_RS18365 SG48_RS18365 3703049 3703276 + hypothetical protein gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18365 SG48_RS18370 SG48_3605 SG48_RS18370 3703339 3704946 - periplasmic dipeptide transporter DppABCDF is involved in the transport of dipeptides%3B also binds heme and mediates chemotaxis to dipeptides gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18370 SG48_RS18375 SG48_RS18375 SG48_RS18375 3705298 3705558 - hypothetical protein gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18375 SG48_RS18380 SG48_3606 SG48_RS18380 3705857 3705933 - tRNA-Pro tRNA gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18380 SG48_RS18385 SG48_3607 SG48_RS18385 3706025 3707716 - phosphoethanolamine transferase EptB catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18385 SG48_RS18390 SG48_3608 SG48_RS18390 3708040 3709248 - pyruvate-inducible inner membrane protein transporter gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18390 SG48_RS18395 SG48_3609 SG48_RS18395 3709477 3710175 - autotransporter beta-domain protein gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18395 SG48_RS18400 SG48_3610 SG48_RS18400 3710333 3710896 + DNA-3-methyladenine glycosylase 1 gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18400 SG48_RS18405 SG48_3611 SG48_RS18405 3710893 3711333 + GNAT family acetyltransferase gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18405 SG48_RS18410 SG48_3612 SG48_RS18410 3711302 3713581 - biotin sulfoxide reductase catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18410 SG48_RS18415 SG48_3613 SG48_RS18415 3713788 3714447 + lipoprotein gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18415 SG48_RS18420 SG48_3614 SG48_RS18420 3714551 3715525 + glyoxylate/hydroxypyruvate reductase B catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18420 SG48_RS18425 SG48_3615 SG48_RS18425 3715575 3716285 - DUF3053 domain-containing protein gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18425 SG48_RS18430 SG48_3616 SG48_RS18430 3716719 3717009 + transcriptional regulator gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18430 SG48_RS18435 SG48_3617 SG48_RS18435 3717290 3717502 + cold-shock protein gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18435 SG48_RS18440 SG48_3618 SG48_RS18440 3717689 3717841 - protein HokA gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18440 SG48_RS18445 SG48_3620 SG48_RS18445 3717921 3718442 + transposase gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18445 SG48_RS18450 SG48_3621 SG48_RS18450 3718439 3719290 + transposase gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18450 SG48_RS18455 SG48_3623 glyS glyS 3719569 3721638 - glycine--tRNA ligase subunit beta glycine--tRNA ligase beta chain%3B glyS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18455 SG48_RS18460 SG48_3624 SG48_RS18460 3721648 3722559 - glycine--tRNA ligase subunit alpha gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18460 SG48_RS18465 SG48_3625 SG48_RS18465 3722654 3722953 - hypothetical protein gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18465 SG48_RS18470 SG48_3626 SG48_RS18470 3723128 3724123 + hypothetical protein involved in enterobacterial common antigen biosynthesis%3B catalyzes the addition of O-acetyl groups to the N-acetyl-D-glucosamine residues of the trisaccharide repeat units of the enterobacterial common antigen gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18470 SG48_RS18475 SG48_3627 SG48_RS18475 3724165 3724602 - hypothetical protein gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18475 SG48_RS18480 SG48_3628 SG48_RS18480 3724648 3724989 - hypothetical protein gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18480 SG48_RS18485 SG48_3629 SG48_RS18485 3725158 3726612 - xylulose kinase catalyzes the formation of D-xylulose-5-phosphate fro D-xylulose gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18485 SG48_RS18490 SG48_3630 SG48_RS18490 3726684 3728006 - xylose isomerase catalyzes the interconversion of D-xylose to D-xylulose gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18490 SG48_RS18495 SG48_3631 xylF xylF 3728372 3729364 + D-xylose-binding periplasmic protein periplasmic substrate-binding component of the ATP-dependent xylose transport system%3B high affinity gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18495 SG48_RS18500 SG48_3632 SG48_RS18500 3729442 3730983 + xylose import ATP-binding protein XylG with XylFH is part of the high affinity xylose ABC transporter gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18500 SG48_RS18505 SG48_3633 SG48_RS18505 3730961 3732142 + xylose ABC transporter permease gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18505 SG48_RS18510 SG48_3634 SG48_RS18510 3732220 3733398 + xylose operon regulatory protein gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18510 SG48_RS18515 SG48_3635 SG48_RS18515 3733594 3734418 - protein bax gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18515 SG48_RS18520 SG48_3636 malS malS 3734738 3736768 + alpha-amylase periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB%3B hydrolyzes alpha-(1%2C4) glycosidic linkages%3B contains internal disulfide bonds gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18520 SG48_RS18525 SG48_3637 avtA avtA 3736946 3738199 + valine--pyruvate aminotransferase transaminase C%3B catalyzes transamination of alanine%2C valine%2C and 2-aminobutyrate with their respective 2-keto acids%3B also catalyzes terminal step in valine biosynthesis gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18525 SG48_RS18530 SG48_RS18530 SG48_RS18530 3738203 3738331 + hypothetical protein gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18530 SG48_RS18535 SG48_3638 SG48_RS18535 3738350 3738823 - hydrogenase 4Fe-4S ferredoxin-type component gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18535 SG48_RS18540 SG48_3639 SG48_RS18540 3738925 3739773 - transcriptional regulator gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18540 SG48_RS18545 SG48_3640 SG48_RS18545 3739974 3740972 + 2%2C3-diketo-L-gulonate reductase NAD(P)H-dependent%3B catalyzes the reduction of 2%2C3-diketo-L-gulonate to 3-keto-L-gulonate gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18545 SG48_RS18550 SG48_3641 SG48_RS18550 3740984 3741451 + hypothetical protein gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18550 SG48_RS18555 SG48_3642 SG48_RS18555 3741569 3742042 + 2%2C3-diketo-L-gulonate TRAP transporter permease membrane-spanning protein involved in uptake of 2%2C3-diketo-L-gulonate%3B part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18555 SG48_RS18560 SG48_3643 SG48_RS18560 3742045 3743322 + 2%2C3-diketo-L-gulonate TRAP transporter permease TRAP family transporter%3B with YiaMO is involved in the uptake of L-dehydroascorbate gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18560 SG48_RS18565 SG48_3644 SG48_RS18565 3743335 3744321 + 2%2C3-diketo-L-gulonate ABC transporter substrate-binding protein involved in the transport of 2%2C3-diketo-L-gulonate gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18565 SG48_RS18570 SG48_3645 SG48_RS18570 3744325 3745821 + L-xylulose/3-keto-L-gulonate kinase catalyzes the formation of L-xylulose 5-phosphate and 3-dehydro-L-gulonate 6-phosphate from L-xylulose or 3-dehydro-L-gulonate%2C respectively gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18570 SG48_RS18575 SG48_3646 sgbH sgbH 3745818 3746480 + 3-keto-L-gulonate-6-phosphate decarboxylase sgbH catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18575 SG48_RS18580 SG48_3647 SG48_RS18580 3746473 3747333 + L-xylulose 5-phosphate 3-epimerase L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated%3B may be involved in the utilization of 2%2C3-diketo-L-gulonate gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18580 SG48_RS18585 SG48_3648 araD araD 3747327 3748022 + L-ribulose-5-phosphate 4-epimerase SgbE catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18585 SG48_RS18590 SG48_3651 SG48_RS18590 3748369 3749109 - outer membrane protein gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18590 SG48_RS18595 SG48_3652 SG48_RS18595 3749233 3750207 + transcriptional regulator gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18595 SG48_RS18600 SG48_3653 SG48_RS18600 3750204 3751340 - hypothetical protein gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18600 SG48_RS18605 SG48_3654 SG48_RS18605 3751346 3751669 - hypothetical protein gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18605 SG48_RS18610 SG48_RS18610 SG48_RS18610 3751783 3751995 + membrane protein gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18610 SG48_RS18615 SG48_3655 SG48_RS18615 3752214 3753752 - aldehyde dehydrogenase B catalyzes the oxidation of acetaldehyde%2C benzaldehyde%2C propionaldehyde and other aldehydes gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18615 SG48_RS18620 SG48_3656 SG48_RS18620 3753917 3755068 - alcohol dehydrogenase gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18620 SG48_RS18625 SG48_3657 SG48_RS18625 3755258 3757102 - selenocysteine-specific translation elongation factor gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18625 SG48_RS18630 SG48_3658 SG48_RS18630 3757099 3758490 - L-seryl-tRNA(Sec) selenium transferase catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18630 SG48_RS18635 SG48_3659 SG48_RS18635 3758588 3759196 - glutathione S-transferase gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18635 SG48_RS18640 SG48_3660 SG48_RS18640 3759424 3763557 + RHS element protein RhsA gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18640 SG48_RS18645 SG48_3661 SG48_RS18645 3763578 3764420 + hypothetical protein gene gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18645 SG48_RS18650 SG48_RS18650 SG48_RS18650 3764468 3765163 + hypothetical protein gene gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18650 SG48_RS18655 SG48_3663 SG48_RS18655 3765418 3765879 + hypothetical protein gene gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18655 SG48_RS18660 SG48_RS18660 SG48_RS18660 3766586 3767024 + hypothetical protein gene gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18660 SG48_RS18665 SG48_3668 SG48_RS18665 3767484 3768620 - hypothetical protein gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18665 SG48_RS18670 SG48_3669 SG48_RS18670 3768623 3768985 - DUF3302 domain-containing protein gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18670 SG48_RS18675 SG48_3670 SG48_RS18675 3769522 3771435 + PTS mannitol EIICBA component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIC forms the translocation channel and contains the specific substrate-binding site%3B subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit%3B subunit IIB transfers the phosphoryl group to the substrate gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18675 SG48_RS18680 SG48_3671 SG48_RS18680 3771665 3772813 + mannitol-1-phosphate 5-dehydrogenase gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18680 SG48_RS18685 SG48_3672 SG48_RS18685 3772810 3773400 + hypothetical protein gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18685 SG48_RS18690 SG48_3673 SG48_RS18690 3773412 3773621 - hypothetical protein gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18690 SG48_RS18695 SG48_3674 SG48_RS18695 3773906 3774268 + DUF2810 domain-containing protein gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18695 SG48_RS18700 SG48_3675 SG48_RS18700 3774640 3776295 + L-lactate permease gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18700 SG48_RS18705 SG48_3676 SG48_RS18705 3776295 3777071 + dual role activator/repressor for lldPRD operon represses the lctPRD operon gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18705 SG48_RS18710 SG48_3677 lldD lldD 3777068 3778258 + lactate dehydrogenase flavin mononucleotide-dependent dehydrogenase%3B functions in aerobic respiration and also has a role in anaerobic nitrate respiration gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18710 SG48_RS18715 SG48_3678 SG48_RS18715 3778456 3778929 + tRNA (cytidine(34)-2'-O)-methyltransferase member of the SPOUT superfamily of RNA methyltransferases gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18715 SG48_RS18720 SG48_3679 cysE cysE 3778982 3779803 - serine acetyltransferase catalyzes the O-acetylation of serine gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18720 SG48_RS18725 SG48_3680 SG48_RS18725 3779883 3780902 - glycerol-3-phosphate dehydrogenase [NAD(P)+] gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18725 SG48_RS18730 SG48_3681 SG48_RS18730 3780902 3781369 - protein-export protein SecB molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm%3B in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18730 SG48_RS18735 SG48_3682 SG48_RS18735 3781432 3781683 - glutaredoxin gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18735 SG48_RS18740 SG48_3683 SG48_RS18740 3781825 3782256 - hypothetical protein gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18740 SG48_RS18745 SG48_3684 SG48_RS18745 3782501 3784045 + 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18745 SG48_RS18750 SG48_3685 SG48_RS18750 3784055 3785338 + peptidase M37 gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18750 SG48_RS18755 SG48_3686 SG48_RS18755 3785342 3786301 + polysaccharide deacetylase gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18755 SG48_RS18760 SG48_3687 SG48_RS18760 3786288 3787322 - LPS(HepIII)-glucuronic acid glycosyltransferase gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18760 SG48_RS18765 SG48_3688 tdh tdh 3787561 3788586 - l-threonine 3-dehydrogenase converts threonine and NAD to 1%2C2-amino-3-oxobutanoate and NADH%3B functions in threonine catabolism gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18765 SG48_RS18770 SG48_3689 SG48_RS18770 3788596 3789792 - 2-amino-3-ketobutyrate CoA ligase catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18770 SG48_RS18775 SG48_3690 SG48_RS18775 3790067 3790924 - protein HtrL gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18775 SG48_RS18780 SG48_3691 rfaD rfaD 3791228 3792160 + ADP-L-glycero-D-manno-heptose-6-epimerase catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18780 SG48_RS18785 SG48_3692 SG48_RS18785 3792170 3793216 + ADP-heptose--LPS heptosyltransferase 2 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18785 SG48_RS18790 SG48_3693 SG48_RS18790 3793220 3794179 + LPS heptosyltransferase 1 gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18790 SG48_RS18795 SG48_3694 SG48_RS18795 3794189 3795448 + O-antigen ligase gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18795 SG48_RS18800 SG48_3695 SG48_RS18800 3795480 3796553 - LPS 1%2C2-N-acetylglucosaminetransferase gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18800 SG48_RS18805 SG48_3696 SG48_RS18805 3796586 3797437 - 3-deoxy-D-manno-oct-2-ulosonate III transferase WaaZ gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18805 SG48_RS18810 SG48_3697 SG48_RS18810 3797508 3798206 - LPS core heptose(II) kinase RfaY catalyzes the phosphorylation of heptose(II) of the outer membrane lipopolysaccharide core gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18810 SG48_RS18815 SG48_3698 SG48_RS18815 3798224 3799240 - LPS 1%2C2-glucosyltransferase gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18815 SG48_RS18820 SG48_3699 SG48_RS18820 3799280 3800299 - LPS 1%2C3-galactosyltransferase gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18820 SG48_RS18825 SG48_3700 SG48_RS18825 3800299 3801378 - LPS 1%2C6-galactosyltransferase gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18825 SG48_RS18830 SG48_3701 SG48_RS18830 3801422 3802357 - LPS biosynthesis protein gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18830 SG48_RS18835 SG48_3702 SG48_RS18835 3802394 3803191 - LPS core heptose(I) kinase RfaP catalyzes the phosphorylation of heptose I in the lipopolysaccharide core gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18835 SG48_RS18840 SG48_3703 SG48_RS18840 3803184 3804308 - LPS biosynthesis protein catalyzes the addition of the first glucose residue to the LPS core gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18840 SG48_RS18845 SG48_3704 SG48_RS18845 3804305 3805339 - LPS core heptosyltransferase RfaQ catalyzes the transfer of heptose(III) to heptose(II) in the lipopolysaccharide inner core gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18845 SG48_RS18850 SG48_3705 SG48_RS18850 3805781 3807058 + 3-deoxy-D-manno-octulosonic acid transferase catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18850 SG48_RS18855 SG48_3706 coaD coaD 3807066 3807545 + phosphopantetheine adenylyltransferase Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18855 SG48_RS18860 SG48_3707 SG48_RS18860 3807584 3808393 - formamidopyrimidine-DNA glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18860 SG48_RS18865 SG48_3708 rpmG rpmG 3808491 3808658 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18865 SG48_RS18870 SG48_3709 rpmB rpmB 3808679 3808915 - 50S ribosomal protein L28 required for 70S ribosome assembly gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18870 SG48_RS18875 SG48_3710 SG48_RS18875 3809132 3809800 - hypothetical protein gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18875 SG48_RS18880 SG48_3711 SG48_RS18880 3809972 3811192 + CoA biosynthesis bifunctional protein CoaBC catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C which is then decarboxylated to form 4'-phosphopantotheine gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18880 SG48_RS18885 SG48_3712 SG48_RS18885 3811170 3811628 + deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18885 SG48_RS18890 SG48_3713 slmA slmA 3811735 3812331 + nucleoid occlusion factor SlmA FtsZ binding protein%3B synthetically lethal with a defect in the Min system%3B this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly gene gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18890 SG48_RS18895 SG48_3714 pyrE pyrE 3812368 3813009 - orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18895 SG48_RS18900 SG48_3715 rph rph 3813104 3813790 - inactive ribonuclease PH RNase PH%3B tRNA nucleotidyltransferase%3B forms hexamers in Bacillus subtilis%3B phosphoroltic 3'-5' exoribonuclease%3B involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs gene gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18900 SG48_RS18905 SG48_3716 SG48_RS18905 3813917 3814780 + hypothetical protein gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18905 SG48_RS18910 SG48_3717 dinD dinD 3815001 3815825 + DNA-damage-inducible protein D gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18910 SG48_RS18915 SG48_3718 SG48_RS18915 3816115 3816732 + hypothetical protein gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18915 SG48_RS18920 SG48_3719 ligB ligB 3816729 3818411 - DNA ligase B this ligase is similar to LigA but it lacks the C-terminal BRCT domain%3B catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18920 SG48_RS18925 SG48_3720 gmk gmk 3818669 3819292 + guanylate kinase Essential for recycling GMP and indirectly%2C cGMP gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18925 SG48_RS18930 SG48_3721 rpoZ rpoZ 3819347 3819622 + DNA-directed RNA polymerase subunit omega Promotes RNA polymerase assembly%3B latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18930 SG48_RS18935 SG48_3722 SG48_RS18935 3819641 3821749 + bifunctional (p)ppGpp synthetase II/ guanosine-3'%2C5'-bis pyrophosphate 3'-pyrophosphohydrolase gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18935 SG48_RS18940 SG48_3723 SG48_RS18940 3821756 3822445 + tRNA (guanosine(18)-2'-O)-methyltransferase specifically modifies tRNA at position G18 gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18940 SG48_RS18945 SG48_3724 SG48_RS18945 3822451 3824532 + ATP-dependent DNA helicase RecG catalyzes branch migration in Holliday junction intermediates gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18945 SG48_RS18950 SG48_3725 SG48_RS18950 3824701 3825906 - sodium/glutamate symport carrier protein is involved with the sodium-dependent uptake of glutamate gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18950 SG48_RS18955 SG48_3726 SG48_RS18955 3826186 3827577 + xanthine permease XanP high-affinity transporter for xanthine gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18955 SG48_RS18960 SG48_3727 SG48_RS18960 3827698 3829407 + AsmA family protein gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18960 SG48_RS18965 SG48_3728 SG48_RS18965 3829460 3831778 - alpha-xylosidase catalyzes the transfer of alpha-xylosyl residue gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18965 SG48_RS18970 SG48_3729 SG48_RS18970 3831788 3833170 - inner membrane symporter YicJ may be involved in the transport of galactosides-pentoses-hexuronides gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18970 SG48_RS18975 SG48_3730 SG48_RS18975 3833463 3833557 + tRNA-Sec tRNA gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18975 SG48_RS18980 SG48_RS18980 SG48_RS18980 3833666 3833812 + hypothetical protein gene gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18980 SG48_RS18985 SG48_3732 SG48_RS18985 3834194 3835378 + sugar efflux transporter C gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18985 SG48_RS18990 SG48_3733 SG48_RS18990 3835489 3836412 + transporter gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18990 SG48_RS18995 SG48_3734 SG48_RS18995 3836416 3837234 - lipoprotein 28 gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS18995 SG48_RS19000 SG48_RS19000 SG48_RS19000 3837332 3837451 + hypothetical protein gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19000 SG48_RS19005 SG48_3735 SG48_RS19005 3837456 3837749 + hypothetical protein gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19005 SG48_RS19010 SG48_3736 nepI nepI 3837790 3838980 - purine ribonucleoside efflux pump NepI experimental results in Escherichia coli suggest that this gene encodes an inosine export protein%3B member of major facilitator superfamily%3B MFS gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19010 SG48_RS19015 SG48_3737 SG48_RS19015 3839191 3839643 - DUF1198 domain-containing protein gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19015 SG48_RS19020 SG48_3738 SG48_RS19020 3839696 3841108 - adenine permease involved in the transport or adenine gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19020 SG48_RS19025 SG48_3739 SG48_RS19025 3841205 3842971 + adenine deaminase catalyzes the formation of hypoxanthine from adenine%3B in E. coli this activity has been detected in mutant strains but not in wild type gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19025 SG48_RS19030 SG48_3740 uhpT uhpT 3843017 3844408 - hexose phosphate transporter cytoplasmic membrane protein that functions as a monomer%3B catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19030 SG48_RS19035 SG48_3741 SG48_RS19035 3844546 3845865 - regulatory protein UhpC membrane protein regulates uhpT expression gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19035 SG48_RS19040 SG48_3742 SG48_RS19040 3845875 3847377 - sensor protein UhpB Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph gene gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19040 SG48_RS19045 SG48_3743 SG48_RS19045 3847377 3847967 - transcriptional regulator response regulator in two-component regulatory system wtih UhpB%3B phosphorylated UhpA is a positive activator uhpT%2C a hexose phosphates transporter gene gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19045 SG48_RS19050 SG48_3744 SG48_RS19050 3848043 3848333 - acetolactate synthase isozyme 1 small subunit with IlvB catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase small subunit gene gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19050 SG48_RS19055 SG48_3745 SG48_RS19055 3848337 3850025 - acetolactate synthase isozyme 1 large subunit gene gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19055 SG48_RS19060 SG48_3746 SG48_RS19060 3850131 3850229 - IlvBN operon leader peptide gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19060 SG48_RS19065 SG48_RS19065 SG48_RS19065 3850216 3850506 + hypothetical protein gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19065 SG48_RS19070 SG48_RS19070 SG48_RS19070 3850503 3850661 + hypothetical protein gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19070 SG48_RS19075 SG48_3748 SG48_RS19075 3850794 3850883 + small toxic protein TisB gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19075 SG48_RS19080 SG48_3749 emrD emrD 3851163 3852347 + multidrug resistance protein D multidrug efflux protein involved in adaptation to low energy shock gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19080 SG48_RS19085 SG48_3750 SG48_RS19085 3852355 3852852 - hypothetical protein gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19085 SG48_RS19090 SG48_3751 SG48_RS19090 3852849 3853211 - hypothetical protein gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19090 SG48_RS19095 SG48_3752 SG48_RS19095 3853201 3853548 - hypothetical protein gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19095 SG48_RS19100 SG48_3753 SG48_RS19100 3853656 3854105 + hypothetical protein gene gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19100 SG48_RS19105 SG48_3754 SG48_RS19105 3854152 3855645 - sulfatase/phosphatase superfamily protein gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19105 SG48_RS19110 SG48_3755 SG48_RS19110 3855642 3857357 - transporter uncharacterized member of the SSS superfamily of sodium-dependent solute transporters%3B unknown function gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19110 SG48_RS19115 SG48_3756 SG48_RS19115 3857524 3858417 + AraC family transcriptional regulator gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19115 SG48_RS19120 SG48_RS19120 SG48_RS19120 3858590 3859228 - inactive 6-phospho-alpha-glucosidase gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19120 SG48_RS19125 SG48_RS19125 SG48_RS19125 3859228 3859713 - phosphotransferase enzyme IIB component GlvB gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19125 SG48_RS19130 SG48_RS19130 SG48_RS19130 3859738 3860844 - permease gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19130 SG48_RS19135 SG48_3759 SG48_RS19135 3861140 3861856 + transcriptional regulator gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19135 SG48_RS19140 SG48_3760 SG48_RS19140 3861853 3863514 - transporter gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19140 SG48_RS19145 SG48_3761 SG48_RS19145 3863710 3864138 - heat-shock protein IbpB 16 kDa heat shock protein B%3B associates with aggregated proteins%2C together with ibpA%2C to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress%3B ATP-independent gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19145 SG48_RS19150 SG48_3762 SG48_RS19150 3864250 3864663 - heat-shock protein IbpA with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19150 SG48_RS19155 SG48_RS19155 SG48_RS19155 3865041 3865301 + hypothetical protein gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19155 SG48_RS19160 SG48_3764 SG48_RS19160 3865303 3866517 - hypothetical protein gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19160 SG48_RS19165 SG48_3765 SG48_RS19165 3866618 3867682 + protein CbrA FAD/NAD(P)-binding domain gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19165 SG48_RS19170 SG48_3766 SG48_RS19170 3867679 3868971 - D-galactonate transporter gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19170 SG48_RS19175 SG48_3767 SG48_RS19175 3869091 3870239 - D-galactonate dehydratase 2 gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19175 SG48_RS19180 SG48_3768 SG48_RS19180 3870236 3870853 - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate%3B functions in galactonate metabolism gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19180 SG48_RS19185 SG48_3769 SG48_RS19185 3870837 3871715 - 2-dehydro-3-deoxygalactonokinase catalyzes the formation of 2-dehydro-3-deoxy-D-galactonate 6-phosphate from 2-dehydro-3-deoxy-D-galactonate gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19185 SG48_RS19190 SG48_3770 SG48_RS19190 3871712 3872401 - transcriptional regulator gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19190 SG48_RS19195 SG48_3771 SG48_RS19195 3872679 3873335 + hypothetical protein gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19195 SG48_RS19200 SG48_3772 SG48_RS19200 3873381 3874193 - sugar phosphatase YidA YidA%3B catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate)%2C mannose 1-phosphate and p-nitrophenyl phosphate%3B hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form%3B member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19200 SG48_RS19205 SG48_3773 SG48_RS19205 3874308 3874706 - DUF937 domain-containing protein gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19205 SG48_RS19210 SG48_RS19210 SG48_RS19210 3874726 3874926 - hypothetical protein gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19210 SG48_RS19215 SG48_3774 gyrB gyrB 3874946 3877360 - DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19215 SG48_RS19220 SG48_3775 recF recF 3877389 3878462 - DNA recombination protein RecF Required for DNA replication%3B binds preferentially to single-stranded%2C linear DNA gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19220 SG48_RS19225 SG48_3776 SG48_RS19225 3878462 3879562 - DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19225 SG48_RS19230 SG48_3777 dnaA dnaA 3879567 3880970 - chromosomal replication initiator protein DnaA binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication%3B can also affect transcription of multiple genes including itself. gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19230 SG48_RS19235 SG48_3778 rpmH rpmH 3881577 3881717 + 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19235 SG48_RS19240 SG48_3779 rnpA rnpA 3881734 3882093 + ribonuclease P protein component protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19240 SG48_RS19245 SG48_3780 SG48_RS19245 3882057 3882314 + membrane protein insertion efficiency factor YidD gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19245 SG48_RS19250 SG48_3781 SG48_RS19250 3882317 3883963 + protein translocase component YidC functions to insert inner membrane proteins into the IM in Escherichia coli%3B interacts with transmembrane segments%3B functions in both Sec-dependent and -independent membrane insertion%3B similar to Oxa1p in mitochondria gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19250 SG48_RS19255 SG48_3782 trmE trmE 3884069 3885433 + tRNA modification GTPase MnmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19255 SG48_RS19260 SG48_3783 SG48_RS19260 3885676 3885750 + tryptophanase leader peptide gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19260 SG48_RS19265 SG48_3784 tnaA tnaA 3885971 3887386 + tryptophanase tryptophan indole-lyase%3B catalyzes the formation of indole and pyruvate from tryptophan%3B also has xysteine desulfhydrase activity gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19265 SG48_RS19270 SG48_3785 SG48_RS19270 3887477 3888724 + low affinity tryptophan permease tryptophan transporter of high affinity gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19270 SG48_RS19275 SG48_3786 SG48_RS19275 3888856 3890031 + multidrug resistance protein MdtL Confers resistance to chloramphenicol gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19275 SG48_RS19280 SG48_3787 SG48_RS19280 3890006 3890965 + transcriptional regulator Involved in anaerobic NO protection gene gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19280 SG48_RS19285 SG48_3788 SG48_RS19285 3891122 3891871 + 4'-phosphopantetheinyl transferase gene gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19285 SG48_RS19290 SG48_3789 SG48_RS19290 3891893 3892459 + chromate reductase gene gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19290 SG48_RS19295 SG48_3790 SG48_RS19295 3892513 3893850 - adenine permease AdeP involved in the transport or adenine gene gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19295 SG48_RS19300 SG48_3791 SG48_RS19300 3894015 3894680 + 6-phosphogluconate phosphatase YieH%3B catalyzes the dephosphorylation of phosphoenolpyruvate%2C AMP and p-nitrophenyl phosphate%3B purine and pyrimidine nucleotides are secondary substrates%3B member of the haloacid dehalogenase-like hydrolases superfamily gene gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19300 SG48_RS19305 SG48_3792 SG48_RS19305 3894747 3895214 + protein CbrB might be involved in hypersensitivity to nitrofurzone gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19305 SG48_RS19310 SG48_3793 SG48_RS19310 3895263 3895850 + hypothetical protein gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19310 SG48_RS19315 SG48_3794 SG48_RS19315 3895912 3896634 - 6-phosphogluconolactonase gene gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19315 SG48_RS19320 SG48_3795 SG48_RS19320 3896649 3897818 - xylanase gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19320 SG48_RS19325 SG48_3796 SG48_RS19325 3897845 3899461 - porin BglH gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19325 SG48_RS19330 SG48_3797 SG48_RS19330 3899530 3900942 - 6-phospho-beta-glucosidase BglB gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19330 SG48_RS19335 SG48_3798 SG48_RS19335 3900961 3902838 - PTS beta-glucoside EIIBCA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19335 SG48_RS19340 SG48_3799 SG48_RS19340 3902972 3903808 - cryptic beta-glucoside bgl operon antiterminator positive regulator of the beta-glucoside operon%3B transcriptional antiterminator gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19340 SG48_RS19345 SG48_3800 SG48_RS19345 3904094 3904819 - phosphate-specific transport system accessory protein PhoU regulates several genes involved in high affinity phosphate uptake%3B under conditions of high phosphate concentrations downregulates the PHO regulon gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19345 SG48_RS19350 SG48_3801 SG48_RS19350 3904834 3905607 - phosphate import ATP-binding protein PstB gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19350 SG48_RS19355 SG48_3802 pstA pstA 3905790 3906680 - phosphate ABC transporter permease Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19355 SG48_RS19360 SG48_3803 pstC pstC 3906680 3907639 - phosphate ABC transporter permease part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19360 SG48_RS19365 SG48_3804 SG48_RS19365 3907726 3908766 - phosphate-binding protein gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19365 SG48_RS19370 SG48_3805 SG48_RS19370 3909080 3910909 - glutamine--fructose-6-phosphate aminotransferase [isomerizing] Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19370 SG48_RS19375 SG48_3806 glmU glmU 3911071 3912441 - bifunctional protein GlmU forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19375 SG48_RS19380 SG48_3807 atpC atpC 3912794 3913213 - ATP synthase epsilon chain part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19380 SG48_RS19385 SG48_3808 SG48_RS19385 3913234 3914616 - ATP synthase subunit beta gene gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19385 SG48_RS19390 SG48_3809 SG48_RS19390 3914643 3915506 - ATP synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19390 SG48_RS19395 SG48_3810 SG48_RS19395 3915557 3917098 - ATP synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19395 SG48_RS19400 SG48_3811 SG48_RS19400 3917111 3917644 - ATP synthase subunit delta Produces ATP from ADP in the presence of a proton gradient across the membrane%3B the delta subunit is part of the catalytic core of the ATP synthase complex gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19400 SG48_RS19405 SG48_3812 SG48_RS19405 3917659 3918129 - ATP synthase subunit b Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19405 SG48_RS19410 SG48_3813 SG48_RS19410 3918191 3918430 - ATP synthase subunit c Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19410 SG48_RS19415 SG48_3814 SG48_RS19415 3918477 3919292 - ATP synthase subunit a Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19415 SG48_RS19420 SG48_3815 SG48_RS19420 3919301 3919681 - ATP synthase I Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation gene gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19420 SG48_RS19425 SG48_3816 gidB gidB 3920298 3920921 - ribosomal RNA small subunit methyltransferase G glucose-inhibited division protein B%3B SAM-dependent methyltransferase%3B methylates the N7 position of guanosine in position 527 of 16S rRNA gene gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19425 SG48_RS19430 SG48_3817 gidA gidA 3920985 3922874 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GidA%3B glucose-inhibited cell division protein A%3B involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs gene gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19430 SG48_RS19435 SG48_3818 SG48_RS19435 3923253 3923696 - protein MioC An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19435 SG48_RS19440 SG48_3819 SG48_RS19440 3923786 3924244 - AsnC family transcriptional regulator transcriptional repressor of asnA which codes for aspartate-ammonia ligase gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19440 SG48_RS19445 SG48_3820 SG48_RS19445 3924396 3925388 + aspartate--ammonia ligase catalyzes the formation of asparagine from aspartate and ammonia gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19445 SG48_RS19450 SG48_3821 SG48_RS19450 3925393 3926844 - protein ViaA contains a von Willibrand factor type A domain%3B stimulates the ATPase activity of RavA gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19450 SG48_RS19455 SG48_3822 SG48_RS19455 3926838 3928334 - ATPase RavA interacts with LdcI%2C lysine decarboxylase%3B may be active in late log/ early stationary phase gene gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19455 SG48_RS19460 SG48_3823 trkD trkD 3928557 3930425 + low affinity potassium transport system protein kup Responsible for the low-affinity transport of potassium into the cell%3B involved in potassium ion uptake under hyper-osmotic stress at a low pH gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19460 SG48_RS19465 SG48_3824 SG48_RS19465 3930592 3931011 + D-ribose pyranase cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose%3B RbsD is required for efficient ribose utilization in E. coli%3B rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19465 SG48_RS19470 SG48_3825 SG48_RS19470 3931019 3932524 + ribose import ATP-binding protein RbsA gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19470 SG48_RS19475 SG48_3826 rbsC rbsC 3932529 3933494 + ribose ABC transporter permease functions to transport ribose at high affinity%3B forms a complex with RbsA2C2B gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19475 SG48_RS19480 SG48_3827 SG48_RS19480 3933519 3934409 + D-ribose-binding periplasmic protein periplasmic substrate-binding component of the ATP-dependent ribose transport system gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19480 SG48_RS19485 SG48_3828 SG48_RS19485 3934535 3935464 + ribokinase catalyzes the formation of D-ribose 5-phosphate from ribose gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19485 SG48_RS19490 SG48_3829 SG48_RS19490 3935477 3936460 + LacI family transcriptional regulator binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19490 SG48_RS19495 SG48_3830 SG48_RS19495 3936426 3937853 - transporter HsrA gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19495 SG48_RS19500 SG48_3831 SG48_RS19500 3937876 3938568 - transcriptional regulator gene gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19500 SG48_RS19505 SG48_3832 SG48_RS19505 3939047 3940602 + 16S ribosomal RNA rRNA gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19505 SG48_RS19510 SG48_3833 SG48_RS19510 3940676 3940751 + tRNA-Glu tRNA gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19510 SG48_RS19515 SG48_3834 SG48_RS19515 3940936 3943860 + 23S ribosomal RNA rRNA gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19515 SG48_RS19520 SG48_3835 SG48_RS19520 3943943 3944058 + 5S ribosomal RNA rRNA gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19520 SG48_RS19525 SG48_3836 SG48_RS19525 3944113 3944189 + tRNA-Asp tRNA gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19525 SG48_RS19530 SG48_3837 SG48_RS19530 3944198 3944273 + tRNA-Trp tRNA gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19530 SG48_RS19535 SG48_3838 SG48_RS19535 3944369 3945208 - transcriptional regulator Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19535 SG48_RS19540 SG48_3839 SG48_RS19540 3945327 3945665 + hypothetical protein gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19540 SG48_RS19545 SG48_3840 SG48_RS19545 3945690 3947210 - magnesium chelatase and transcriptional regulator among the AAA+ ATPases%2C the YifB protease family belongs to the Helix 2 insert clade%3B unknown function gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19545 SG48_RS19550 SG48_3841 SG48_RS19550 3947563 3947661 + IlvGMEDA operon leader peptide gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19550 SG48_RS19555 SG48_RS19555 SG48_RS19555 3947801 3949445 + acetolactate synthase catalytic subunit catalyzes the formation of 2-acetolactate from pyruvate%3B also known as acetolactate synthase large subunit gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19555 SG48_RS19560 SG48_3844 ilvM ilvM 3949442 3949705 + acetolactate synthase isozyme 2 small subunit gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19560 SG48_RS19565 SG48_3845 SG48_RS19565 3949725 3950654 + branched-chain-amino-acid aminotransferase gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19565 SG48_RS19570 SG48_3846 SG48_RS19570 3950719 3952569 + dihydroxy-acid dehydratase catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19570 SG48_RS19575 SG48_3847 SG48_RS19575 3952572 3954116 + L-threonine dehydratase biosynthetic IlvA threonine deaminase%3B threonine dehydratase%3B in Escherichia coli%2C IlvA is part of the isoleucine biosynthetic pathway gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19575 SG48_RS19580 SG48_3848 SG48_RS19580 3954168 3955061 - transcriptional regulator participates in controlling several genes involved in isoleucine and valine biosynthesis%3B activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19580 SG48_RS19585 SG48_3849 SG48_RS19585 3955211 3956686 + ketol-acid reductoisomerase catalyzes the formation of (R)-2%2C3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19585 SG48_RS19590 SG48_3850 SG48_RS19590 3956773 3957054 - peptidyl-prolyl cis-trans isomerase rotamase C%3B accelerates isomerization of the peptidyl prolyl bond gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19590 SG48_RS19595 SG48_RS19595 SG48_RS19595 3957253 3957701 - hypothetical protein gene gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19595 SG48_RS19600 SG48_3852 SG48_RS19600 3957918 3959939 + ATP-dependent DNA helicase Rep single-stranded DNA-dependent ATPase%3B initiates unwinding at a nick in the DNA%3B involved in DNA replication gene gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19600 SG48_RS19605 SG48_3853 SG48_RS19605 3959986 3961470 - guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase catalyzes the conversion of guanosine 5'-triphosphate%2C3'-diphosphate (pppGpp) to guanosine 5'-diphosphate%2C3'-diphosphate (ppGpp)%3B pppGpp and ppGpp control the stringent response during amino acid starvation gene gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19605 SG48_RS19610 SG48_3854 SG48_RS19610 3961606 3962871 - ATP-dependent RNA helicase RhlB enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome%2C a multi-enzyme complex important in RNA processing and messenger RNA degradation gene gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19610 SG48_RS19615 SG48_3855 trxA trxA 3963002 3963331 + thioredoxin gene gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19615 SG48_RS19620 SG48_RS19620 SG48_RS19620 3963472 3963573 + rho operon leader peptide gene gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19620 SG48_RS19625 SG48_3856 rho rho 3963658 3964917 + transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19625 SG48_RS19630 SG48_RS19630 SG48_RS19630 3964927 3965145 + hypothetical protein gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19630 SG48_RS19635 SG48_3857 SG48_RS19635 3965157 3966260 + undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase catalyzes the formation of alpha-N-acetylglucosaminyl-pyrophosphoryl-undecaprenyl from alpha-N-acetylglucosaminyl 1-phosphate and the lipid carrier undecaprenyl phosphate gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19635 SG48_RS19640 SG48_3858 SG48_RS19640 3966272 3967318 + LPS biosynthesis protein Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19640 SG48_RS19645 SG48_3859 SG48_RS19645 3967419 3968504 + UDP-N-acetylglucosamine 2-epimerase gene gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19645 SG48_RS19650 SG48_3860 wecC wecC 3968501 3969763 + UDP-N-acetyl-D-mannosamine dehydrogenase catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid gene gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19650 SG48_RS19655 SG48_3861 SG48_RS19655 3969763 3970830 + dTDP-glucose 4%2C6-dehydratase gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19655 SG48_RS19660 SG48_3862 SG48_RS19660 3970849 3971730 + glucose-1-phosphate thymidylyltransferase 2 gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19660 SG48_RS19665 SG48_3863 SG48_RS19665 3971708 3972382 + dTDP-fucosamine acetyltransferase gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19665 SG48_RS19670 SG48_3864 SG48_RS19670 3972387 3973517 + dTDP-4-amino-4%2C6-dideoxygalactose aminotransferase catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19670 SG48_RS19675 SG48_3865 SG48_RS19675 3973519 3974769 + protein WzxE involved in the movement of lipid III across the membrane gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19675 SG48_RS19680 SG48_3866 SG48_RS19680 3974766 3975845 + TDP-N-acetylfucosamine--lipid II N-acetylfucosaminyltransferase catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19680 SG48_RS19685 SG48_3867 SG48_RS19685 3975842 3977194 + ECA polysaccharide chain elongation protein enterobacterial common antigen polymerase gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19685 SG48_RS19690 SG48_3868 SG48_RS19690 3977197 3977937 + UDP-N-acetyl-D-mannosaminuronic acid transferase gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19690 SG48_RS19695 SG48_3869 SG48_RS19695 3978128 3979513 + transporter involved in the transport across the cytoplasmic membrane of D-alanine%2C D-serine and glycine gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19695 SG48_RS19700 SG48_3870 SG48_RS19700 3979616 3979692 + tRNA-Arg tRNA gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19700 SG48_RS19705 SG48_3871 SG48_RS19705 3979751 3979826 + tRNA-His tRNA gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19705 SG48_RS19710 SG48_3872 SG48_RS19710 3979847 3979933 + tRNA-Leu tRNA gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19710 SG48_RS19715 SG48_3873 SG48_RS19715 3979976 3980052 + tRNA-Pro tRNA gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19715 SG48_RS19720 SG48_3874 SG48_RS19720 3980199 3981434 + anaerobic sulfatase maturase AslB gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19720 SG48_RS19725 SG48_3875 SG48_RS19725 3981593 3983248 - arylsulfatase gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19725 SG48_RS19730 SG48_3877 SG48_RS19730 3983927 3985123 - heme biosynthesis protein HemY gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19730 SG48_RS19735 SG48_3878 SG48_RS19735 3985126 3986307 - heme biosynthesis operon protein HemX gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19735 SG48_RS19740 SG48_3879 hemD hemD 3986329 3987069 - uroporphyrinogen III methyltransferase catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane%3B functions in tetrapyrrole and heme biosynthesis gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19740 SG48_RS19745 SG48_3880 hemC hemC 3987066 3988007 - porphobilinogen deaminase transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19745 SG48_RS19750 SG48_3881 cyaA cyaA 3988394 3990940 + adenylate cyclase catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19750 SG48_RS19755 SG48_3882 cyaY cyaY 3990980 3991300 - protein CyaY iron-dependent inhibitor of iron-sulfur cluster formation%3B iron-binding and oxidizing protein%3B defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease%3B based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly gene gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19755 SG48_RS19760 SG48_3883 SG48_RS19760 3991763 3991966 + membrane protein gene gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19760 SG48_RS19765 SG48_3884 dapF dapF 3992003 3992827 + diaminopimelate epimerase involved in lysine biosynthesis%3B DAP epimerase%3B produces DL-diaminopimelate from LL-diaminopimelate gene gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19765 SG48_RS19770 SG48_3885 SG48_RS19770 3992824 3993531 + DUF484 domain-containing protein gene gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19770 SG48_RS19775 SG48_3886 xerC xerC 3993528 3994424 + tyrosine recombinase XerC site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19775 SG48_RS19780 SG48_3887 SG48_RS19780 3994424 3995140 + flavin mononucleotide phosphatase YigB YigB%3B member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein%3B unknown function gene gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19780 SG48_RS19785 SG48_3888 uvrD uvrD 3995224 3997386 + DNA helicase II unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present%3B involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. gene gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19785 SG48_RS19790 SG48_3889 SG48_RS19790 3997533 3998297 - DUF2233 domain-containing protein gene gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19790 SG48_RS19795 SG48_RS19795 SG48_RS19795 3998310 3998423 + hypothetical protein gene gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19795 SG48_RS19800 SG48_3890 SG48_RS19800 3998667 3999617 + magnesium transporter CorA responsible for the influx of magnesium ions gene gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19800 SG48_RS19805 SG48_3891 SG48_RS19805 3999660 4000040 - DUF2628 domain-containing protein gene gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19805 SG48_RS19810 SG48_3892 SG48_RS19810 4000054 4000434 - hypothetical protein gene gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19810 SG48_RS19815 SG48_3893 SG48_RS19815 4000529 4001419 - protein RarD gene gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19815 SG48_RS19820 SG48_3894 SG48_RS19820 4001471 4001938 - hypothetical protein gene gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19820 SG48_RS19825 SG48_3895 SG48_RS19825 4002103 4002972 + phospholipase A1 catalyzes the hydrolysis of phosphatidylcholine gene gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19825 SG48_RS19830 SG48_3896 SG48_RS19830 4003105 4004934 + ATP-dependent DNA helicase RecQ functions in blocking illegitimate recombination%2C enhancing topoisomerase activity%2C initiating SOS signaling and clearing blocked replication forks%3B component of the RecF recombinational pathway gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19830 SG48_RS19835 SG48_3897 SG48_RS19835 4004998 4005618 + threonine efflux protein gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19835 SG48_RS19840 SG48_3898 rhtB rhtB 4005680 4006300 - homoserine/homoserine lactone efflux protein gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19840 SG48_RS19845 SG48_3899 SG48_RS19845 4006411 4007433 + lysophospholipase L2 lecithinase B%3B catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine%3B can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19845 SG48_RS19850 SG48_3900 SG48_RS19850 4007441 4008241 + pyridoxal phosphate phosphatase YigL gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19850 SG48_RS19855 SG48_3901 SG48_RS19855 4008317 4009216 + EamA-like transporter gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19855 SG48_RS19860 SG48_3902 SG48_RS19860 4009104 4010057 - transcriptional regulator homocysteine-binding%3B positive regulator of metA%2C metE and metH gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19860 SG48_RS19865 SG48_3903 SG48_RS19865 4010294 4012555 + 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19865 SG48_RS19870 SG48_3904 SG48_RS19870 4012595 4013410 - carboxymethylenebutenolidase gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19870 SG48_RS19875 SG48_3905 SG48_RS19875 4013672 4014433 + uridine phosphorylase catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate%3B involved in the pyrimidine salvage pathway gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19875 SG48_RS19880 SG48_3906 SG48_RS19880 4014574 4016001 + DNA recombination protein RmuC YigN%3B nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence%3B transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19880 SG48_RS19885 SG48_3907 ubiE ubiE 4016096 4016851 + ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone and menaquinone gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19885 SG48_RS19890 SG48_3908 SG48_RS19890 4016865 4017470 + ubiquinone biosynthesis protein UbiJ gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19890 SG48_RS19895 SG48_3909 ubiB ubiB 4017467 4019107 + hypothetical protein an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone%3B functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis%3B similar to eukaryotic proteins that exhibit kinase functions gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19895 SG48_RS19900 SG48_3910 tatA tatA 4019186 4019455 + protein translocase TatA TatA%3B similar to TatE that is found in some proteobacteria%3B part of system that translocates proteins with a conserved twin arginine motif across the inner membrane%3B capable of translocating folded substrates typically those with bound cofactors%3B similar to a protein import system in thylakoid membranes gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19900 SG48_RS19905 SG48_3911 SG48_RS19905 4019459 4019974 + Sec-independent protein translocase TatB mediates the export of protein precursors bearing twin-arginine signal peptides gene gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19905 SG48_RS19910 SG48_3912 SG48_RS19910 4019977 4020753 + preprotein translocase subunit TatC with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19910 SG48_RS19915 SG48_3913 SG48_RS19915 4020795 4021577 + Tat-linked quality control protein TatD magnesium dependent%3B involved in quality control of mutated Tat exported substrates%3B not involved in the Sec-independent protein export system gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19915 SG48_RS19920 SG48_3914 rfaH rfaH 4021574 4022062 - transcription antitermination protein RfaH gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19920 SG48_RS19925 SG48_3915 SG48_RS19925 4022229 4023722 + 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19925 SG48_RS19930 SG48_3916 fre fre 4023768 4024469 + NAD(P)H-flavin reductase NAD(P)H-flavin reductase%3B catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide%3B in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19930 SG48_RS19935 SG48_3917 fadA fadA 4024850 4026013 - 3-ketoacyl-CoA thiolase FadA%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadB%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19935 SG48_RS19940 SG48_3918 fadB fadB 4026023 4028212 - fatty acid oxidation complex subunit alpha includes enoyl-CoA hydratase%2C delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase%2C 3-hydroxyacyl-CoA dehydrogenase%2C and 3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities%3B forms a heterotetramer with FadA%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19940 SG48_RS19945 SG48_3919 SG48_RS19945 4028402 4029733 + Xaa-Pro dipeptidase catalyzes the hydrolysis of dipeptides with a proline at the C-terminal%3B also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19945 SG48_RS19950 SG48_3920 SG48_RS19950 4029733 4030347 + IMPACT family member YigZ gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19950 SG48_RS19955 SG48_3921 SG48_RS19955 4030386 4031837 + trk system potassium uptake protein trkH gene gene3984 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19955 SG48_RS19960 SG48_3922 hemG hemG 4031849 4032394 + protoporphyrinogen IX dehydrogenase [menaquinone] catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX gene gene3985 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19960 SG48_RS19965 SG48_3923 SG48_RS19965 4032770 4034325 + 16S ribosomal RNA rRNA gene3986 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19965 SG48_RS19970 SG48_3924 SG48_RS19970 4034382 4034458 + tRNA-Ile tRNA gene3987 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19970 SG48_RS19975 SG48_3925 SG48_RS19975 4034501 4034576 + tRNA-Ala tRNA gene3988 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19975 SG48_RS19980 SG48_3926 SG48_RS19980 4034751 4037682 + 23S ribosomal RNA rRNA gene3989 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19980 SG48_RS19985 SG48_3927 SG48_RS19985 4037760 4037875 + 5S ribosomal RNA rRNA gene3990 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19985 SG48_RS19990 SG48_3928 SG48_RS19990 4038147 4038674 - molybdopterin-guanine dinucleotide biosynthesis adapter protein in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway gene gene3991 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19990 SG48_RS19995 SG48_3929 mobA mobA 4038656 4039240 - molybdenum cofactor guanylyltransferase in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis gene gene3992 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS19995 SG48_RS20000 SG48_3930 SG48_RS20000 4039310 4039579 + hypothetical protein gene gene3993 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20000 SG48_RS20005 SG48_3931 SG48_RS20005 4039656 4040642 + protein RdoA catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro%3B specific substrate in vivo has not been identified yet%3B plays a role in long-term cell survival and expression of surface appendages gene gene3994 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20005 SG48_RS20010 SG48_3932 SG48_RS20010 4040659 4041285 + thiol:disulfide interchange protein DsbA gene gene3995 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20010 SG48_RS20015 SG48_3933 SG48_RS20015 4041440 4042870 + DUF945 domain-containing protein gene gene3996 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20015 SG48_RS20020 SG48_3934 SG48_RS20020 4042911 4043843 - acyltransferase gene gene3997 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20020 SG48_RS20025 SG48_RS20025 SG48_RS20025 4043963 4044205 - hypothetical protein gene gene3998 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20025 SG48_RS20030 SG48_3935 SG48_RS20030 4044207 4046993 + DNA polymerase I gene gene3999 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20030 SG48_RS20035 SG48_3937 SG48_RS20035 4047374 4048006 - GTP-binding protein gene gene4000 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20035 SG48_RS20040 SG48_3939 SG48_RS20040 4048588 4049097 + der GTPase-activating protein YihI gene gene4001 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20040 SG48_RS20045 SG48_3940 SG48_RS20045 4049286 4050659 + coproporphyrinogen III oxidase catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III gene gene4002 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20045 SG48_RS20050 SG48_3941 SG48_RS20050 4050888 4050998 - hypothetical protein gene gene4003 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20050 SG48_RS20055 SG48_3942 glnG glnG 4051110 4052519 - nitrogen regulation protein NR(I) response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes%3B interacts with sigma-54 gene gene4004 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20055 SG48_RS20060 SG48_3943 glnL glnL 4052531 4053580 - PAS domain-containing two-component system sensor histidine kinase sensory histidine kinase in two-component regulatory system with GlnG%3B acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation gene gene4005 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20060 SG48_RS20065 SG48_3944 glnA glnA 4053866 4055275 - glutamine synthetase forms a homododecamer%3B forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate%3B also functions in the assimilation of ammonia%3B highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues%3B addition of adenylyl groups results in inactivation of the enzyme gene gene4006 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20065 SG48_RS20070 SG48_RS20070 SG48_RS20070 4055254 4055487 - hypothetical protein gene gene4007 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20070 SG48_RS20075 SG48_3945 SG48_RS20075 4055648 4057471 + GTP-binding protein gene gene4008 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20075 SG48_RS20080 SG48_3946 SG48_RS20080 4057688 4058398 + transcriptional regulator gene gene4009 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20080 SG48_RS20085 SG48_3947 SG48_RS20085 4058406 4059386 + sugar phosphate isomerase gene gene4010 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20085 SG48_RS20090 SG48_3948 SG48_RS20090 4059488 4060753 + hypothetical protein gene gene4011 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20090 SG48_RS20095 SG48_3949 ompL ompL 4060844 4061536 - porin porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall%3B specific substrate still unknown gene gene4012 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20095 SG48_RS20100 SG48_3950 SG48_RS20100 4061604 4063007 - sulfoquinovose importer gene gene4013 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20100 SG48_RS20105 SG48_3951 SG48_RS20105 4063050 4064435 - 2%2C3-dihydroxypropane-1-sulfonate exporter gene gene4014 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20105 SG48_RS20110 SG48_3952 SG48_RS20110 4064481 4066517 - alpha-glucosidase YihQ gene gene4015 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20110 SG48_RS20115 SG48_3953 SG48_RS20115 4066716 4067618 - aldose-1-epimerase gene gene4016 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20115 SG48_RS20120 SG48_3954 SG48_RS20120 4067756 4068997 - sulfoquinovose isomerase gene gene4017 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20120 SG48_RS20125 SG48_3955 SG48_RS20125 4069014 4069892 - sulfofructosephosphate aldolase gene gene4018 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20125 SG48_RS20130 SG48_3956 SG48_RS20130 4069916 4070812 - 3-sulfolactaldehyde reductase catalyzes the formation of gamma hydroxybutyrate from succinate semialdehyde gene gene4019 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20130 SG48_RS20135 SG48_3957 SG48_RS20135 4070980 4071876 + sulfofructose kinase gene gene4020 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20135 SG48_RS20140 SG48_3958 SG48_RS20140 4071910 4072695 + DeoR family transcriptional regulator gene gene4021 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20140 SG48_RS20145 SG48_3959 SG48_RS20145 4072794 4073393 + alpha-D-glucose-1-phosphate phosphatase YihX gene gene4022 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20145 SG48_RS20150 SG48_3960 SG48_RS20150 4073387 4074259 + membrane protein gene gene4023 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20150 SG48_RS20155 SG48_3961 SG48_RS20155 4074256 4074693 + D-aminoacyl-tRNA deacylase hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr)%3B possible defense mechanism against a harmful effect of D-tyrosine gene gene4024 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20155 SG48_RS20160 SG48_3962 SG48_RS20160 4074738 4075679 + hypothetical protein gene gene4025 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20160 SG48_RS20165 SG48_3963 SG48_RS20165 4076532 4076750 + hypothetical protein gene gene4026 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20165 SG48_RS20170 SG48_3964 SG48_RS20170 4076968 4077210 + hypothetical protein gene gene4027 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20170 SG48_RS20175 SG48_RS20175 SG48_RS20175 4077226 4077375 - hypothetical protein gene gene4028 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20175 SG48_RS20180 SG48_3965 SG48_RS20180 4077540 4078469 - protein FdhE required for the formation of active formate dehydrogenase gene gene4029 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20180 SG48_RS20185 SG48_3966 SG48_RS20185 4078466 4079101 - formate dehydrogenase cytochrome b556(fdo) subunit cytochrome b556(FDO) component%3B heme containing gene gene4030 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20185 SG48_RS20190 SG48_3967 SG48_RS20190 4079098 4080000 - formate dehydrogenase-O iron-sulfur subunit beta subunit%3B involved in the use of formate as an electron donor during aerobic respiration%3B acts to transfer electrons from the major(alpha subunit) to the cytochrome b556(gamma subunit) gene gene4031 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20190 SG48_RS20195 SG48_RS20195 SG48_RS20195 4080013 4082427 - formate dehydrogenase subunit alpha gene gene4032 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20195 SG48_RS20200 SG48_RS20200 SG48_RS20200 4082476 4083063 - sulfate ABC transporter substrate-binding protein gene gene4033 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20200 SG48_RS20205 SG48_3969 SG48_RS20205 4083257 4084090 + protein FdhD involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth gene gene4034 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20205 SG48_RS20210 SG48_3970 SG48_RS20210 4084243 4085298 + DUF3829 domain-containing protein gene gene4035 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20210 SG48_RS20215 SG48_3971 SG48_RS20215 4085348 4087096 - frv operon regulator%3B contains a PTS EIIA domain repressor of the frv operon%2C involved in phosphoenolpyruvate:sugar phosphotransferase system gene gene4036 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20215 SG48_RS20220 SG48_3972 SG48_RS20220 4087096 4088166 - peptidase gene gene4037 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20220 SG48_RS20225 SG48_3973 SG48_RS20225 4088156 4089607 - fructose-like PTS system EIIBC component gene gene4038 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20225 SG48_RS20230 SG48_3974 SG48_RS20230 4089618 4090064 - fructose-like phosphotransferase enzyme IIA component with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars%3B possibly responsible for the sugar specificity of the system gene gene4039 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20230 SG48_RS20235 SG48_3975 SG48_RS20235 4090365 4090679 - L-rhamnose mutarotase gene gene4040 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20235 SG48_RS20240 SG48_3976 SG48_RS20240 4090689 4091513 - rhamnulose-1-phosphate aldolase gene gene4041 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20240 SG48_RS20245 SG48_3977 SG48_RS20245 4091964 4093223 - L-rhamnose isomerase catalyzes the formation of L-rhamnulose from L-rhamnose gene gene4042 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20245 SG48_RS20250 SG48_3978 rhaB rhaB 4093220 4094689 - rhamnulokinase catalyzes the ATP-dependent phosphorylation of rhamnulose gene gene4043 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20250 SG48_RS20255 SG48_RS20255 SG48_RS20255 4094768 4094917 + hypothetical protein gene gene4044 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20255 SG48_RS20260 SG48_3979 SG48_RS20260 4094977 4095813 + transcriptional activator RhaS gene gene4045 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20260 SG48_RS20265 SG48_3980 SG48_RS20265 4095887 4096735 + HTH-type transcriptional activator RhaR activates the expression of rhaRS in response to L-rhamnose gene gene4046 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20265 SG48_RS20270 SG48_3981 SG48_RS20270 4096732 4097766 - l-rhamnose-proton symporter transports L-rhamnose and L-lyxose into the cell gene gene4047 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20270 SG48_RS20275 SG48_3982 SG48_RS20275 4098051 4098671 + superoxide dismutase [Mn] SodA%3B manganese binding%3B only present under aerobic conditions%3B destroys free radicals gene gene4048 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20275 SG48_RS20280 SG48_RS20280 SG48_RS20280 4098712 4098828 - hypothetical protein gene gene4049 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20280 SG48_RS20285 SG48_3983 SG48_RS20285 4098931 4099914 + 2-keto-3-deoxygluconate permease transports degraded pectin products into the bacterial cell gene gene4050 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20285 SG48_RS20290 SG48_3984 SG48_RS20290 4100063 4100737 + hypothetical protein gene gene4051 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20290 SG48_RS20295 SG48_3985 cpxA cpxA 4100843 4102216 - two-component system sensor histidine kinase part of two-component CpxA/CpxR system%3B senses envelope stress%3B upregulates a number of periplasmic folding and trafficking factors gene gene4052 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20295 SG48_RS20300 SG48_3986 SG48_RS20300 4102213 4102911 - two-component system response regulator response regulator in two-component regulatory system with CpxA%3B part of the envelope stress response system gene gene4053 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20300 SG48_RS20305 SG48_3987 cpxP cpxP 4103061 4103561 + periplasmic protein CpxP repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA%3B CpxP is degraded by DegP protease especially in the presence of misfolded substrates gene gene4054 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20305 SG48_RS20310 SG48_3988 fieF fieF 4103710 4104612 + ferrous iron and zinc transporter member of cation diffusion facilitator family%3B CDF%3B membrane-bound%3B induced by both zinc and iron%2C but does not induce resistance to zinc%3B can transport zinc(II) in a proton-dependent manner%3B instead this protein induces iron resistance%3B forms dimers gene gene4055 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20310 SG48_RS20315 SG48_3989 SG48_RS20315 4104793 4105755 + ATP-dependent 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene4056 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20315 SG48_RS20320 SG48_3990 SG48_RS20320 4106075 4107064 + sulfate-binding protein gene gene4057 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20320 SG48_RS20325 SG48_3991 SG48_RS20325 4107171 4107926 + CDP-diacylglycerol pyrophosphatase gene gene4058 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20325 SG48_RS20330 SG48_3992 SG48_RS20330 4107981 4108748 - triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene4059 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20330 SG48_RS20335 SG48_3993 SG48_RS20335 4108856 4109455 - DUF1454 domain-containing protein gene gene4060 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20335 SG48_RS20340 SG48_3994 SG48_RS20340 4109556 4109996 + membrane protein gene gene4061 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20340 SG48_RS20345 SG48_3995 SG48_RS20345 4110208 4110507 + hypothetical protein gene gene4062 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20345 SG48_RS20350 SG48_3996 SG48_RS20350 4110534 4110962 + universal stress protein D with UspC and Usp E is involved in resistance to UV radiation gene gene4063 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20350 SG48_RS20355 SG48_3997 SG48_RS20355 4110967 4111713 - ferredoxin--NADP reductase gene gene4064 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20355 SG48_RS20360 SG48_3998 SG48_RS20360 4111810 4112820 - fructose 1%2C6-bisphosphatase gene gene4065 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20360 SG48_RS20365 SG48_3999 glpK glpK 4112955 4114463 - glycerol kinase Converts glycerol and ADP to glycerol-3-phosphate and ADP gene gene4066 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20365 SG48_RS20370 SG48_4000 SG48_RS20370 4114486 4115331 - glycerol uptake facilitator protein involved in the transport of glycerol into the cell gene gene4067 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20370 SG48_RS20375 SG48_4001 SG48_RS20375 4115762 4116001 + cell division protein ZapB interacts with FisZ and is necessary for Z-ring formation gene gene4068 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20375 SG48_RS20380 SG48_4002 SG48_RS20380 4116086 4116571 - ribonuclease E activity regulator RraA regulator of RNase E%3B increases half-life and abundance of RNAs%3B interacts with RNase E possibly inhibiting catalytic activity gene gene4069 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20380 SG48_RS20385 SG48_4003 SG48_RS20385 4116664 4117590 - 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase catalyzes the formation of dimethylmenaquinone from 1%2C4-dihydroxy-2-naphthoate and octaprenyl diphosphate gene gene4070 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20385 SG48_RS20390 SG48_4004 hslU hslU 4117657 4118988 - ATP-dependent protease ATPase subunit HslU heat shock protein involved in degradation of misfolded proteins gene gene4071 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20390 SG48_RS20395 SG48_4005 SG48_RS20395 4118998 4119528 - ATP-dependent protease subunit HslV gene gene4072 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20395 SG48_RS20400 SG48_4006 SG48_RS20400 4119621 4120475 - cell division protein FtsN gene gene4073 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20400 SG48_RS20405 SG48_4007 SG48_RS20405 4120672 4121697 - transcriptional regulator negatively controls the transcription initiation of genes such as deoCABD%2C udp%2C and cdd encoding catabolizing enzymes and nupC%2C nupG%2C and tsx encoding transporting and pore-forming proteins gene gene4074 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20405 SG48_RS20410 SG48_4008 SG48_RS20410 4121853 4124051 - primosomal protein N' binding of PriA to forked DNA starts the assembly of the primosome%2C also possesses 3'-5' helicase activity gene gene4075 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20410 SG48_RS20415 SG48_4009 rpmE rpmE 4124254 4124466 + 50S ribosomal protein L31 RpmE%3B there appears to be two types of ribosomal proteins L31 in bacterial genomes%3B some contain a CxxC motif while others do not%3B Bacillus subtilis has both types%3B the proteins in this cluster have the CXXC motif%3B RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth%3B expression of ytiA is controlled by a zinc-specific transcriptional repressor%3B RpmE contains one zinc ion and a CxxC motif is responsible for this binding%3B forms an RNP particle along with proteins L5%2C L18%2C and L25 and 5S rRNA%3B found crosslinked to L2 and L25 and EF-G%3B may be near the peptidyltransferase site of the 50S ribosome gene gene4076 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20415 SG48_RS20420 SG48_4010 SG48_RS20420 4124527 4125135 - lipid binding hydrolase DUF830 family protein gene gene4077 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20420 SG48_RS20425 SG48_4011 SG48_RS20425 4125319 4125636 - met repressor when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis gene gene4078 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20425 SG48_RS20430 SG48_4012 SG48_RS20430 4125913 4127073 + cystathionine gamma-synthase catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine gene gene4079 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20430 SG48_RS20435 SG48_4013 metL metL 4127076 4129508 + bifunctional aspartokinase/homoserine dehydrogenase 2 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene4080 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20435 SG48_RS20440 SG48_RS20440 SG48_RS20440 4129647 4129781 - hypothetical protein gene gene4081 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20440 SG48_RS20445 SG48_4014 metF metF 4129857 4130747 + 5%2C10-methylenetetrahydrofolate reductase MTHFR%3B catalyzes NADH-linked reduction of 5%2C10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor gene gene4082 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20445 SG48_RS20450 SG48_4015 SG48_RS20450 4131076 4133256 + catalase-peroxidase gene gene4083 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20450 SG48_RS20455 SG48_4016 SG48_RS20455 4133349 4134254 + permease gene gene4084 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20455 SG48_RS20460 SG48_4017 SG48_RS20460 4134281 4134898 - DUF1287 domain-containing protein gene gene4085 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20460 SG48_RS20465 SG48_RS20465 SG48_RS20465 4135010 4135129 - hypothetical protein gene gene4086 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20465 SG48_RS20470 SG48_4018 gldA gldA 4135173 4136276 - glycerol dehydrogenase forms dimers and octamers%3B involved in conversion of glycerol to dihydroxy-acetone gene gene4087 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20470 SG48_RS20475 SG48_4019 SG48_RS20475 4136287 4136949 - fructose-6-phosphate aldolase 2 similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene4088 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20475 SG48_RS20480 SG48_4020 SG48_RS20480 4136961 4139462 - multiphosphoryl transfer protein 2 Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein HPr%3B HPr transfers the phosphoryl group to subunit A%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene4089 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20480 SG48_RS20485 SG48_4021 SG48_RS20485 4139771 4140850 + fructose-like permease IIC component 2 gene gene4090 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20485 SG48_RS20490 SG48_4022 SG48_RS20490 4140865 4141185 + fructose-like phosphotransferase enzyme IIB component 2 FrwB with FrwC%2C FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell%3B cytoplasmic protein that interacts with complex EIIA%3B contains the second phosphorylation site of the PTS gene gene4091 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20490 SG48_RS20495 SG48_4023 pflD pflD 4141236 4143533 + formate acetyltransferase 2 involved in production of D-lactate from glucose under microaerobic conditions%3B cytoplasmic protein gene gene4092 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20495 SG48_RS20500 SG48_4024 SG48_RS20500 4143499 4144377 + pyruvate formate-lyase 2-activating enzyme gene gene4093 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20500 SG48_RS20505 SG48_4025 SG48_RS20505 4144379 4144720 + fructose-like phosphotransferase enzyme IIB component 3 FrwD with FrwB%2C FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell%3B phosphorylated by EIIA%3B FrwB homolog gene gene4094 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20505 SG48_RS20510 SG48_4026 SG48_RS20510 4144707 4145558 - AraC family transcriptional regulator gene gene4095 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20510 SG48_RS20515 SG48_4027 SG48_RS20515 4145773 4147506 - phosphoethanolamine transferase EptC gene gene4096 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20515 SG48_RS20520 SG48_4028 SG48_RS20520 4147688 4150339 - phosphoenolpyruvate carboxylase catalyzes the formation of oxaloacetate from phosphoenolpyruvate gene gene4097 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20520 SG48_RS20525 SG48_RS20525 SG48_RS20525 4150557 4150949 - hypothetical protein gene gene4098 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20525 SG48_RS20530 SG48_4029 SG48_RS20530 4150937 4152088 - acetylornithine deacetylase catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis gene gene4099 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20530 SG48_RS20535 SG48_4030 SG48_RS20535 4152242 4153246 + N-acetyl-gamma-glutamyl-phosphate reductase gene gene4100 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20535 SG48_RS20540 SG48_4031 SG48_RS20540 4153257 4154030 + acetylglutamate kinase gene gene4101 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20540 SG48_RS20545 SG48_4032 SG48_RS20545 4154091 4155464 + argininosuccinate lyase catalyzes the formation of arginine from (N-L-arginino)succinate gene gene4102 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20545 SG48_RS20550 SG48_4034 SG48_RS20550 4155731 4156648 + hydrogen peroxide-inducible genes activator Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG%2C gor%2C ahpC%2C ahpF%2C oxyS%2C dps%2C fur and grxA gene gene4103 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20550 SG48_RS20555 SG48_4035 SG48_RS20555 4156631 4158031 - soluble pyridine nucleotide transhydrogenase catalyzes the conversion of NADPH to NADH gene gene4104 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20555 SG48_RS20560 SG48_4036 SG48_RS20560 4158365 4159012 + transcriptional regulator negatively controls the expression of fabA and fabB%2C genes involved in the unsaturated fatty acid biosynthesis gene gene4105 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20560 SG48_RS20565 SG48_4037 SG48_RS20565 4159012 4159371 + hypothetical protein gene gene4106 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20565 SG48_RS20570 SG48_4038 SG48_RS20570 4159411 4160511 - tRNA/tmRNA (uracil-C(5))-methyltransferase catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs gene gene4107 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20570 SG48_RS20575 SG48_4039 btuB btuB 4160880 4162724 + vitamin B12 transporter BtuB involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space gene gene4108 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20575 SG48_RS20580 SG48_4040 SG48_RS20580 4162738 4163526 + glutamate racemase converts L-glutamate to D-glutamate%2C a component of peptidoglycan gene gene4109 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20580 SG48_RS20585 SG48_4041 SG48_RS20585 4163898 4165453 + 16S ribosomal RNA rRNA gene4110 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20585 SG48_RS20590 SG48_4042 SG48_RS20590 4165613 4165688 + tRNA-Glu tRNA gene4111 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20590 SG48_RS20595 SG48_4043 SG48_RS20595 4165873 4168802 + 23S ribosomal RNA rRNA gene4112 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20595 SG48_RS20600 SG48_4044 SG48_RS20600 4168880 4168995 + 5S ribosomal RNA rRNA gene4113 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20600 SG48_RS20605 SG48_4045 murB murB 4169298 4170326 + UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene4114 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20605 SG48_RS20610 SG48_4046 SG48_RS20610 4170323 4171288 + bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor catalyzes the formation of biotinyl-5'-AMP%2C also acts as a transcriptional repressor of the biotin operon gene gene4115 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20610 SG48_RS20615 SG48_4047 SG48_RS20615 4171317 4172273 - type I pantothenate kinase gene gene4116 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20615 SG48_RS20620 SG48_RS20620 SG48_RS20620 4172454 4172609 - hypothetical protein gene gene4117 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20620 SG48_RS20625 SG48_4048 SG48_RS20625 4172629 4172704 + tRNA-Thr tRNA gene4118 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20625 SG48_RS20630 SG48_4049 SG48_RS20630 4172713 4172797 + tRNA-Tyr tRNA gene4119 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20630 SG48_RS20635 SG48_4050 SG48_RS20635 4172914 4172988 + tRNA-Gly tRNA gene4120 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20635 SG48_RS20640 SG48_4051 SG48_RS20640 4172995 4173070 + tRNA-Thr tRNA gene4121 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20640 SG48_RS20645 SG48_4052 tuf tuf 4173185 4174369 + translation elongation factor EF-Tu 2 EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene4122 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20645 SG48_RS20650 SG48_4053 secE secE 4174599 4174982 + protein translocase subunit SecE forms a complex with SecY and SecG%3B SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane%2C a process driven by ATP and a proton-motive force gene gene4123 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20650 SG48_RS20655 SG48_4054 nusG nusG 4174984 4175529 + transcription termination/antitermination protein NusG Modulates Rho-dependent transcription termination gene gene4124 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20655 SG48_RS20660 SG48_4055 SG48_RS20660 4175688 4176116 + 50S ribosomal protein L11 gene gene4125 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20660 SG48_RS20665 SG48_4056 SG48_RS20665 4176120 4176824 + 50S ribosomal protein L1 gene gene4126 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20665 SG48_RS20670 SG48_4057 rplJ rplJ 4177237 4177734 + 50S ribosomal protein L10 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit gene gene4127 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20670 SG48_RS20675 SG48_4058 rplL rplL 4177801 4178166 + 50S ribosomal protein L7/L12 present in two forms%3B L12 is normal%2C while L7 is aminoacylated at the N-terminal serine%3B the only multicopy ribosomal protein%3B 4:1 ratio of L7/L12 per ribosome%3B two L12 dimers bind L10%3B critically important for translation efficiency and fidelity%3B stimulates GTPase activity of translation factors gene gene4128 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20675 SG48_RS20680 SG48_4059 rpoB rpoB 4178486 4182514 + DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene4129 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20680 SG48_RS20685 SG48_4060 SG48_RS20685 4182591 4186814 + DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene4130 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20685 SG48_RS20690 SG48_4061 SG48_RS20690 4187027 4187566 + heat-shock protein C gene gene4131 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20690 SG48_RS20695 SG48_4063 thiH thiH 4187976 4189109 - 2-iminoacetate synthase in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS%3B with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine%2C cysteine and 1-deoxy-D-xylulose-5-phosphate%3B forms a complex with ThiG%3B contains an iron-sulfur center gene gene4132 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20695 SG48_RS20700 SG48_4064 SG48_RS20700 4189106 4189876 - thiazole synthase gene gene4133 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20700 SG48_RS20705 SG48_4065 SG48_RS20705 4189878 4190078 - thiamine biosynthesis protein ThiS with ThiF%2C ThiG%2C and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate gene gene4134 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20705 SG48_RS20710 SG48_4066 SG48_RS20710 4190062 4190817 - thiamine biosynthesis protein ThiS ATP-dependent adenylate transferase%2C transfers adenyl moiety to the MoeD subunit of molybdopterin synthase gene gene4135 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20710 SG48_RS20715 SG48_4067 SG48_RS20715 4190810 4191445 - thiamine-phosphate synthase catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate gene gene4136 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20715 SG48_RS20720 SG48_4068 SG48_RS20720 4191445 4193340 - phosphomethylpyrimidine synthase catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis gene gene4137 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20720 SG48_RS20725 SG48_4069 SG48_RS20725 4193573 4194049 - regulator of sigma D binds specifically to the major sigma factor sigma 70%3B active in stationary phase gene gene4138 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20725 SG48_RS20730 SG48_4070 nudC nudC 4194144 4194917 + NADH pyrophosphatase can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH%3B requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates gene gene4139 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20730 SG48_RS20735 SG48_4071 hemE hemE 4194957 4196021 + uroporphyrinogen decarboxylase catalyzes the formation of coproporphyrinogen from uroporphyrinogen III gene gene4140 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20735 SG48_RS20740 SG48_4072 SG48_RS20740 4196031 4196702 + endonuclease V Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B cleaves DNA containing urea residues%2C AP sites%2C base mismatches%2C insertion/deletion mismatches%2C flaps%2C and pseudo-Y structures gene gene4141 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20740 SG48_RS20745 SG48_4073 SG48_RS20745 4196745 4197335 + hypothetical protein gene gene4142 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20745 SG48_RS20750 SG48_4074 SG48_RS20750 4197522 4197794 + DNA-binding protein HU-alpha gene gene4143 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20750 SG48_RS20755 SG48_4075 SG48_RS20755 4197807 4198502 + DUF1481 domain-containing protein gene gene4144 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20755 SG48_RS20760 SG48_4076 zraP zraP 4198504 4198929 - zinc resistance-associated protein gene gene4145 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20760 SG48_RS20765 SG48_4077 SG48_RS20765 4199167 4200564 + two-component system sensor histidine kinase gene gene4146 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20765 SG48_RS20770 SG48_4078 SG48_RS20770 4200561 4201886 + ZraR family transcriptional regulator DNA-binding response regulator in two-component regulatory system with ZraS%3B response regulator/sigma54 interaction protein gene gene4147 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20770 SG48_RS20775 SG48_4079 SG48_RS20775 4201883 4203172 - phosphoribosylamine--glycine ligase catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis gene gene4148 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20775 SG48_RS20780 SG48_4080 purH purH 4203184 4204773 - bifunctional purine biosynthesis protein PurH involved in de novo purine biosynthesis gene gene4149 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20780 SG48_RS20785 SG48_4081 SG48_RS20785 4205041 4205424 + stress-induced protein gene gene4150 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20785 SG48_RS20790 SG48_4082 SG48_RS20790 4205487 4205930 - GNAT family acetyltransferase gene gene4151 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20790 SG48_RS20795 SG48_4083 SG48_RS20795 4206087 4207016 + homoserine O-succinyltransferase catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis gene gene4152 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20795 SG48_RS20800 SG48_4084 SG48_RS20800 4207285 4208886 + malate synthase A Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle gene gene4153 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20800 SG48_RS20805 SG48_4085 SG48_RS20805 4208916 4210220 + isocitrate lyase gene gene4154 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20805 SG48_RS20810 SG48_4086 aceK aceK 4210403 4212139 + isocitrate dehydrogenase catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity%3B unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol gene gene4155 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20810 SG48_RS20815 SG48_4087 SG48_RS20815 4212108 4214294 - ankyrin repeat protein A gene gene4156 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20815 SG48_RS20820 SG48_4088 SG48_RS20820 4214611 4215435 - acetate operon repressor regulates the glyoxylate bypass operon (aceBAK)%2C which encodes isocitrate lyase%2C malate synthase and isocitrate dehydrogenase kinase/phosphorylase gene gene4157 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20820 SG48_RS20825 SG48_4089 metH metH 4215635 4219318 + methionine synthase one of two methionine synthases in Escherichia coli%3B MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine%3B requires zinc for activity gene gene4158 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20825 SG48_RS20830 SG48_4090 SG48_RS20830 4219538 4221169 + transporter gene gene4159 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20830 SG48_RS20835 SG48_4091 SG48_RS20835 4221260 4221949 - peptidase E peptidase E%3B catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue%3B belongs to peptidase S51 family gene gene4160 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20835 SG48_RS20840 SG48_4092 SG48_RS20840 4222161 4223033 + ribosomal large subunit pseudouridine synthase F catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA gene gene4161 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20840 SG48_RS20845 SG48_4093 SG48_RS20845 4223166 4223438 - DUF3811 domain-containing protein gene gene4162 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20845 SG48_RS20850 SG48_4094 SG48_RS20850 4223691 4225040 - lysine-sensitive aspartokinase 3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP%3B functions in amino acid biosynthesis%3B lysine sensitive gene gene4163 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20850 SG48_RS20855 SG48_4095 pgi pgi 4225565 4227214 + glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene4164 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20855 SG48_RS20860 SG48_4096 SG48_RS20860 4227713 4227955 + polysaccharide production threonine-rich protein gene gene4165 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20860 SG48_RS20865 SG48_4097 SG48_RS20865 4228069 4228707 + polysaccharide production lipoprotein gene gene4166 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20865 SG48_RS20870 SG48_4098 SG48_RS20870 4228704 4229441 + polysaccharide export OMA protein gene gene4167 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20870 SG48_RS20875 SG48_4099 SG48_RS20875 4229441 4231537 + DUF940 domain-containing protein gene gene4168 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20875 SG48_RS20880 SG48_4100 SG48_RS20880 4231584 4231862 - periplasmic protein gene gene4169 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20880 SG48_RS20885 SG48_RS20885 SG48_RS20885 4231863 4232006 + hypothetical protein gene gene4170 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20885 SG48_RS20890 SG48_4101 SG48_RS20890 4232132 4232542 + protein PsiE gene gene4171 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20890 SG48_RS20895 SG48_4102 xylE xylE 4232586 4234061 - D-xylose-proton symporter xylose/proton symporter%3B member of the major facilitator superfamily (MFS) of transporter gene gene4172 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20895 SG48_RS20900 SG48_4103 malG malG 4234433 4235323 - maltose ABC transporter permease with MalKFE is involved in the transport of maltose into the cell gene gene4173 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20900 SG48_RS20905 SG48_4104 malF malF 4235338 4236882 - maltose ABC transporter permease with MalKGE is involved in maltose transport into the cell gene gene4174 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20905 SG48_RS20910 SG48_4105 malE malE 4237036 4238226 - maltose-binding periplasmic protein functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis gene gene4175 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20910 SG48_RS20915 SG48_RS20915 SG48_RS20915 4238319 4238414 - sugar ABC transporter gene gene4176 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20915 SG48_RS20920 SG48_4106 SG48_RS20920 4238591 4239706 + maltose/maltodextrin import ATP-binding protein MalK with malEFG is involved in import of maltose/maltodextrin gene gene4177 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20920 SG48_RS20925 SG48_4107 lamB lamB 4239778 4241118 + maltoporin porin involved in the transport of maltose and maltodextrins gene gene4178 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20925 SG48_RS20930 SG48_4108 SG48_RS20930 4241361 4242281 + maltose operon periplasmic protein gene gene4179 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20930 SG48_RS20935 SG48_RS20935 SG48_RS20935 4242510 4242704 + hypothetical protein gene gene4180 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20935 SG48_RS20940 SG48_RS20940 SG48_RS20940 4242762 4244090 + hypothetical protein in E. coli%2C some yjbl mutations have been reported as suppressors of dnaG mutations gene gene4181 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20940 SG48_RS20945 SG48_4110 ubiC ubiC 4244313 4244810 + Chorismate pyruvate-lyase catalyzes the formation of 4-hydroxybenzoate from chorismate gene gene4182 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20945 SG48_RS20950 SG48_4111 ubiA ubiA 4244823 4245695 + 4-hydroxybenzoate octaprenyltransferase catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate%2C as part of the ubiquinone biosynthesis pathway gene gene4183 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20950 SG48_RS20955 SG48_4112 SG48_RS20955 4245850 4248273 - glycerol-3-phosphate acyltransferase PlsB%3B catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA gene gene4184 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20955 SG48_RS20960 SG48_4113 SG48_RS20960 4248444 4248812 + diacylglycerol kinase catalyzes the phosphorylation of diacylglycerol to form diacylglycerol phosphate gene gene4185 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20960 SG48_RS20965 SG48_4114 SG48_RS20965 4248922 4249530 + LexA repressor Represses a number of genes involved in the response to DNA damage gene gene4186 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20965 SG48_RS20970 SG48_4115 SG48_RS20970 4249603 4250928 + MATE family efflux transporter gene gene4187 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20970 SG48_RS20975 SG48_4116 SG48_RS20975 4251044 4251253 + stress-induced protein%2C UPF0337 family gene gene4188 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20975 SG48_RS20980 SG48_4117 SG48_RS20980 4251295 4251810 - zinc uptake regulation protein Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB gene gene4189 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20980 SG48_RS20985 SG48_4118 SG48_RS20985 4252128 4252382 + hypothetical protein gene gene4190 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20985 SG48_RS20990 SG48_4119 SG48_RS20990 4252406 4253113 + hypothetical protein gene gene4191 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20990 SG48_RS20995 SG48_4120 SG48_RS20995 4253521 4254513 + tRNA-dihydrouridine synthase A gene gene4192 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS20995 SG48_RS21000 SG48_4121 pspG pspG 4254647 4254889 + phage shock protein G coordinately regulated along with pspA%3B PspF-dependent induction in response to secretin overexpression in Yersinia gene gene4193 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21000 SG48_RS21005 SG48_4122 SG48_RS21005 4255055 4256038 - quinone oxidoreductase 1 gene gene4194 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21005 SG48_RS21010 SG48_4123 SG48_RS21010 4256121 4257536 + replicative DNA helicase unwinds double stranded DNA gene gene4195 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21010 SG48_RS21015 SG48_4124 alr alr 4257589 4258668 + alanine racemase biosynthetic converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene4196 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21015 SG48_RS21020 SG48_4125 SG48_RS21020 4258921 4260114 + aromatic-amino-acid aminotransferase catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate gene gene4197 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21020 SG48_RS21025 SG48_RS21025 SG48_RS21025 4260336 4260819 - hypothetical protein gene gene4198 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21025 SG48_RS21030 SG48_4127 aphA aphA 4261221 4261934 + class B acid phosphatase Class B%3B non-specific%3B catalyzes the dephosphorylation of organic phosphomonoesters%3B also has phosphotransferase activity gene gene4199 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21030 SG48_RS21035 SG48_4128 SG48_RS21035 4262045 4262461 + thiamin phosphate synthase gene gene4200 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21035 SG48_RS21040 SG48_4129 SG48_RS21040 4262465 4262821 + hypothetical protein gene gene4201 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21040 SG48_RS21045 SG48_4130 SG48_RS21045 4262856 4265678 - UvrABC system protein A gene gene4202 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21045 SG48_RS21050 SG48_4131 SG48_RS21050 4265932 4266468 + single-stranded DNA-binding protein binds to single stranded DNA and PriA helcase facilitate replication restart gene gene4203 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21050 SG48_RS21055 SG48_4132 SG48_RS21055 4266567 4266848 - membrane protein gene gene4204 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21055 SG48_RS21060 SG48_4133 SG48_RS21060 4267278 4268864 + cyclic-di-GMP phosphodiesterase gene gene4205 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21060 SG48_RS21065 SG48_4134 SG48_RS21065 4268867 4269190 - regulatory protein SoxS regulates genes involved in response to oxidative stress gene gene4206 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21065 SG48_RS21070 SG48_4135 SG48_RS21070 4269276 4269740 + redox-sensitive transcriptional activator SoxR gene gene4207 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21070 SG48_RS21075 SG48_4137 SG48_RS21075 4270286 4271635 + guanine/hypoxanthine permease GhxP gene gene4208 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21075 SG48_RS21080 SG48_4138 SG48_RS21080 4271787 4273436 + cation/proton antiporter gene gene4209 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21080 SG48_RS21085 SG48_4139 SG48_RS21085 4273590 4274882 - hypothetical protein gene gene4210 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21085 SG48_RS21090 SG48_4140 actP actP 4275060 4276709 - cation/acetate symporter ActP member of the sodium:solute symporter family%3B cotranscribed with the acs gene which encodes acetyl coenzyme A synthase%3B mutations affect acetate uptake gene gene4211 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21090 SG48_RS21095 SG48_4141 SG48_RS21095 4276706 4277020 - hypothetical protein gene gene4212 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21095 SG48_RS21100 SG48_4142 SG48_RS21100 4277220 4279178 - acetyl-CoA synthetase Acs%3B catalyzes the conversion of acetate and CoA to acetyl-CoA gene gene4213 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21100 SG48_RS21105 SG48_4143 nrfA nrfA 4279571 4281007 + cytochrome c-552 catalyzes the formate-dependent reduction of nitrite to ammonia%3B cytochrome C552 gene gene4214 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21105 SG48_RS21110 SG48_4144 SG48_RS21110 4281052 4281618 + cytochrome c-type protein NrfB part of nitrite reductase complex%3B NrfB is active at high nitrate conditions%3B NrfA%2C B%2C C%2C and D are essential for the formate-dependent nitrite reduction to ammonia gene gene4215 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21110 SG48_RS21115 SG48_4145 SG48_RS21115 4281615 4282286 + protein NrfC 4Fe4S subunit%3B may be involved in the transfer of electrons from quinones to the c-type cytochromes gene gene4216 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21115 SG48_RS21120 SG48_4146 SG48_RS21120 4282283 4283239 + protein NrfD membrane protein%2C may be involved in the transfer of electrons from quinones to c-type cytochromes gene gene4217 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21120 SG48_RS21125 SG48_4147 SG48_RS21125 4283370 4284977 + heme lyase subunit NrfE with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 gene gene4218 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21125 SG48_RS21130 SG48_4148 SG48_RS21130 4284970 4285353 + formate-dependent nitrite reductase complex subunit NrfF gene gene4219 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21130 SG48_RS21135 SG48_4149 SG48_RS21135 4285350 4285946 + formate-dependent nitrite reductase complex subunit NrfG gene gene4220 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21135 SG48_RS21140 SG48_4150 SG48_RS21140 4286288 4287601 + proton glutamate symport protein gene gene4221 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21140 SG48_RS21145 SG48_4151 SG48_RS21145 4288245 4288934 - hypothetical protein gene gene4222 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21145 SG48_RS21150 SG48_RS21150 SG48_RS21150 4289028 4290707 - formate dehydrogenase subunit alpha gene gene4223 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21150 SG48_RS21155 SG48_RS21155 SG48_RS21155 4290756 4291175 - spermidine/putrescine ABC transporter substrate-binding protein gene gene4224 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21155 SG48_RS21160 SG48_4153 SG48_RS21160 4291373 4292839 - multidrug resistance outer membrane protein MdtP part of a multidrug efflux system involved in resistance to acriflavin%2C puromycin%2C erytjhromycin and tetraphenylarsonium chloride%3B member of the outer membrane factor (OMF) family gene gene4225 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21160 SG48_RS21165 SG48_4154 SG48_RS21165 4292836 4294887 - multidrug resistance protein MdtO possibly part of a tripartite efflux system composed of MdtN%2C MdtO and MdtP which could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene4226 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21165 SG48_RS21170 SG48_4155 SG48_RS21170 4294887 4295918 - multidrug resistance protein MdtN with MdtO and MdtP is involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene4227 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21170 SG48_RS21175 SG48_4156 SG48_RS21175 4295937 4296212 - transporter gene gene4228 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21175 SG48_RS21180 SG48_4157 SG48_RS21180 4296421 4298406 - MBL fold hydrolase gene gene4229 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21180 SG48_RS21185 SG48_4158 SG48_RS21185 4298679 4299608 - D-allose kinase gene gene4230 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21185 SG48_RS21190 SG48_4159 SG48_RS21190 4299592 4300287 - D-allulose-6-phosphate 3-epimerase gene gene4231 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21190 SG48_RS21195 SG48_4160 SG48_RS21195 4300298 4301278 - D-allose ABC transporter permease gene gene4232 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21195 SG48_RS21200 SG48_4161 SG48_RS21200 4301257 4302789 - D-allose import ATP-binding protein AlsA with AlsBC acts to import allose into the cell%3B AlsA contain 2 ATP-binding domains gene gene4233 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21200 SG48_RS21205 SG48_4162 SG48_RS21205 4302916 4303851 - D-allose-binding periplasmic protein gene gene4234 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21205 SG48_RS21210 SG48_4163 SG48_RS21210 4303910 4304800 - RpiR family transcriptional regulator involved in rpiB and als operon repression gene gene4235 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21210 SG48_RS21215 SG48_4164 SG48_RS21215 4305159 4305608 + ribose-5-phosphate isomerase B gene gene4236 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21215 SG48_RS21220 SG48_4165 SG48_RS21220 4305677 4306006 + periplasmic protein gene gene4237 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21220 SG48_RS21225 SG48_4166 phnP phnP 4306153 4306911 - phosphoribosyl 1%2C2-cyclic phosphodiesterase required for the use of phosphonates and phosphite as phosphorus sources gene gene4238 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21225 SG48_RS21230 SG48_4167 SG48_RS21230 4306913 4307347 - protein PhnO PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids%3B part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source%3B Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role gene gene4239 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21230 SG48_RS21235 SG48_4168 SG48_RS21235 4307334 4307891 - ribose 1%2C5-bisphosphate phosphokinase PhnN gene gene4240 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21235 SG48_RS21240 SG48_4169 SG48_RS21240 4307891 4309027 - alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase gene gene4241 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21240 SG48_RS21245 SG48_4170 SG48_RS21245 4309024 4309704 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL gene gene4242 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21245 SG48_RS21250 SG48_4171 phnK phnK 4309815 4310573 - phosphonate C-P lyase gene gene4243 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21250 SG48_RS21255 SG48_4172 SG48_RS21255 4310570 4311415 - alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase gene gene4244 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21255 SG48_RS21260 SG48_4173 SG48_RS21260 4311408 4312472 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI required for the use of phosphonate and phosphite gene gene4245 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21260 SG48_RS21265 SG48_4174 phnH phnH 4312472 4313056 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH gene gene4246 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21265 SG48_RS21270 SG48_4175 SG48_RS21270 4313053 4313505 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG gene gene4247 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21270 SG48_RS21275 SG48_4176 SG48_RS21275 4313506 4314231 - transcriptional regulator may be involved in phosphonate uptake and biodegradation gene gene4248 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21275 SG48_RS21280 SG48_RS21280 SG48_RS21280 4314252 4315039 - phosphonate ABC transporter permease gene gene4249 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21280 SG48_RS21285 SG48_4178 SG48_RS21285 4315145 4316161 - phosphonates-binding periplasmic protein with PhnCE is involved in the transport of phosphonates gene gene4250 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21285 SG48_RS21290 SG48_4179 SG48_RS21290 4316186 4316974 - phosphonates import ATP-binding protein PhnC gene gene4251 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21290 SG48_RS21295 SG48_4180 SG48_RS21295 4317107 4317550 - protein PhnB gene gene4252 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21295 SG48_RS21300 SG48_4181 SG48_RS21300 4318208 4318543 - protein PhnA gene gene4253 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21300 SG48_RS21305 SG48_4182 SG48_RS21305 4318944 4321172 + clamp-binding protein CrfC gene gene4254 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21305 SG48_RS21310 SG48_4183 SG48_RS21310 4321169 4322047 + YjcZ family protein%3B yhjH motility defect suppressor gene gene4255 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21310 SG48_RS21315 SG48_4184 SG48_RS21315 4322311 4323813 + proline/betaine transporter gene gene4256 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21315 SG48_RS21320 SG48_4185 SG48_RS21320 4323925 4324014 + membrane-bound BasS regulator gene gene4257 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21320 SG48_RS21325 SG48_4186 SG48_RS21325 4323990 4325081 - two-component system sensor histidine kinase gene gene4258 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21325 SG48_RS21330 SG48_4187 SG48_RS21330 4325091 4325759 - two-component system response regulator response regulator in two-component regulatory system with BasS gene gene4259 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21330 SG48_RS21335 SG48_4188 SG48_RS21335 4325756 4327399 - phosphoethanolamine transferase EptA gene gene4260 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21335 SG48_RS21340 SG48_4189 SG48_RS21340 4327503 4328840 - arginine/agmatine antiporter gene gene4261 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21340 SG48_RS21345 SG48_4190 SG48_RS21345 4328977 4329738 - transcriptional regulator regulates genes involved in arginine decarboxylase gene gene4262 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21345 SG48_RS21350 SG48_4191 SG48_RS21350 4330063 4332333 - arginine decarboxylase biodegradative%3B catalyzes the formation of agmatine from arginine gene gene4263 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21350 SG48_RS21355 SG48_4192 SG48_RS21355 4332529 4333437 - melibiose operon regulatory protein gene gene4264 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21355 SG48_RS21360 SG48_RS21360 SG48_RS21360 4333469 4333630 + hypothetical protein gene gene4265 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21360 SG48_RS21365 SG48_4193 SG48_RS21365 4333720 4335075 + alpha-galactosidase catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides gene gene4266 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21365 SG48_RS21370 SG48_4194 SG48_RS21370 4335178 4336599 + melibiose carrier protein gene gene4267 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21370 SG48_RS21375 SG48_4195 SG48_RS21375 4336738 4337367 - hypothetical protein gene gene4268 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21375 SG48_RS21380 SG48_4196 SG48_RS21380 4337489 4339135 - fumarate hydratase class I%2C anaerobic catalyzes the formation of malate from fumerate gene gene4269 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21380 SG48_RS21385 SG48_4197 SG48_RS21385 4339213 4340553 - anaerobic C4-dicarboxylate transporter DcuB functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to DcuA%3B DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate%2C malate%2C fumarate and succinate) transporters gene gene4270 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21385 SG48_RS21390 SG48_RS21390 SG48_RS21390 4341019 4341147 + glutamate decarboxylase gene gene4271 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21390 SG48_RS21395 SG48_4198 SG48_RS21395 4341124 4341843 - transcriptional regulator response regulator in two-component regulatory system with DcuS%3B phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration gene gene4272 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21395 SG48_RS21400 SG48_4199 SG48_RS21400 4341840 4343471 - sensor histidine kinase C4-dicarboxylate-sensing histidine kinase%3B part of two-component regulatory system with DcuR%3B regulates anaerobic fumarate respiration gene gene4273 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21400 SG48_RS21405 SG48_4200 SG48_RS21405 4343652 4343882 + hypothetical protein gene gene4274 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21405 SG48_RS21410 SG48_4201 SG48_RS21410 4343894 4344166 + GNAT family acetyltransferase gene gene4275 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21410 SG48_RS21415 SG48_RS21415 SG48_RS21415 4344253 4344468 + hypothetical protein gene gene4276 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21415 SG48_RS21420 SG48_RS21420 SG48_RS21420 4344483 4344689 + hypothetical protein gene gene4277 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21420 SG48_RS21425 SG48_4203 SG48_RS21425 4344717 4344890 + toxin of GhoTS toxin-antitoxin pair%3B membrane-lytic protein%3B stimulator of persister cell formation gene gene4278 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21425 SG48_RS21430 SG48_4204 lysS lysS 4345009 4346526 - lysine--tRNA ligase heat inducible class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene4279 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21430 SG48_RS21435 SG48_4205 SG48_RS21435 4346763 4348220 - dipeptide and tripeptide permease C gene gene4280 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21435 SG48_RS21440 SG48_4206 SG48_RS21440 4348279 4350426 - lysine decarboxylase inducible constitutive%3B catalyzes the formation of cadaverine from lysine gene gene4281 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21440 SG48_RS21445 SG48_4207 cadB cadB 4350506 4351840 - cadaverine/lysine antiporter antiporter protein responsible for lysine import and cadaverine export%3B member of the lysine-dependent acid resistance system 4 (AR4)%3B inner membrane protein gene gene4282 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21445 SG48_RS21450 SG48_4208 SG48_RS21450 4352205 4353743 - transcriptional activator CadC regulates the cadBA operon gene gene4283 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21450 SG48_RS21455 SG48_4210 SG48_RS21455 4354360 4354435 - tRNA-Phe tRNA gene4284 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21455 SG48_RS21460 SG48_4211 SG48_RS21460 4354542 4355117 - transcriptional regulator gene gene4285 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21460 SG48_RS21465 SG48_4212 dipZ dipZ 4355154 4356851 - thiol:disulfide interchange protein DsbD two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm%3B DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm gene gene4286 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21465 SG48_RS21470 SG48_4213 SG48_RS21470 4356827 4357165 - divalent-cation tolerance protein CutA copper binding protein required for copper tolerance%3B involved in resistance toward heavy metals gene gene4287 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21470 SG48_RS21475 SG48_4214 SG48_RS21475 4357281 4358582 - anaerobic C4-dicarboxylate transporter DcuA functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to dcuB gene gene4288 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21475 SG48_RS21480 SG48_4215 aspA aspA 4358700 4360136 - aspartate ammonia-lyase catalyzes the formation of fumarate from aspartate gene gene4289 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21480 SG48_RS21485 SG48_4216 fxsA fxsA 4360473 4360949 + suppressor of F exclusion of phage T7 F exclusion of bacteriophage T7%3B overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7%3B interacts with the F plasmid-encoded PifA protein%3B inner membrane protein gene gene4290 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21485 SG48_RS21490 SG48_4217 SG48_RS21490 4360965 4362221 - hypothetical protein uncharacterized member of the APC superfamily of amino acid transporters%3B unknown function gene gene4291 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21490 SG48_RS21495 SG48_4218 groES groES 4362497 4362790 + molecular chaperone GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene4292 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21495 SG48_RS21500 SG48_4219 groEL groEL 4362834 4364480 + chaperonin GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene4293 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21500 SG48_RS21505 SG48_4220 SG48_RS21505 4364618 4364971 + DUF4156 domain-containing protein gene gene4294 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21505 SG48_RS21510 SG48_4221 SG48_RS21510 4365174 4366043 - hypothetical protein gene gene4295 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21510 SG48_RS21515 SG48_4222 SG48_RS21515 4366438 4367466 - EF-P beta-lysylation protein EpmB gene gene4296 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21515 SG48_RS21520 SG48_4223 SG48_RS21520 4367508 4368074 + elongation factor P gene gene4297 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21520 SG48_RS21525 SG48_4224 SG48_RS21525 4368126 4368251 + entericidin A acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex gene gene4298 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21525 SG48_RS21530 SG48_4225 SG48_RS21530 4368362 4368508 + entericidin B gene gene4299 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21530 SG48_RS21535 SG48_4226 SG48_RS21535 4368684 4369001 + quaternary ammonium compound-resistance protein SugE member of the SMR family of proton-dependent drug efflux transporters%3B quaternary ammonium compound efflux pump%3B confers resistance to cetylpyridinium%2C cetyldimethylethyl ammonium and cetrimide cations gene gene4300 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21535 SG48_RS21540 SG48_4227 SG48_RS21540 4368998 4369531 - hypothetical protein lipocalin%3B globomycin-sensitive outer membrane lipoprotein gene gene4301 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21540 SG48_RS21545 SG48_4228 SG48_RS21545 4369620 4370753 - BlaEC family class C beta-lactamase gene gene4302 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21545 SG48_RS21550 SG48_4229 SG48_RS21550 4370816 4371175 - fumarate reductase subunit D in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane gene gene4303 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21550 SG48_RS21555 SG48_4230 SG48_RS21555 4371186 4371581 - fumarate reductase subunit C part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene4304 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21555 SG48_RS21560 SG48_4231 SG48_RS21560 4371592 4372326 - fumarate reductase iron-sulfur subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene4305 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21560 SG48_RS21565 SG48_4232 SG48_RS21565 4372319 4374127 - fumarate reductase flavoprotein subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene4306 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21565 SG48_RS21570 SG48_4233 SG48_RS21570 4374452 4375429 + elongation factor P--(R)-beta-lysine ligase poxA%3B regulates pyruvate oxidase poxB gene gene4307 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21570 SG48_RS21575 SG48_4234 SG48_RS21575 4375648 4377150 + inner membrane transporter YjeM gene gene4308 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21575 SG48_RS21580 SG48_4235 SG48_RS21580 4377202 4377516 + hypothetical protein gene gene4309 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21580 SG48_RS21585 SG48_4236 SG48_RS21585 4377513 4377827 + hypothetical protein gene gene4310 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21585 SG48_RS21590 SG48_4237 SG48_RS21590 4377856 4381179 - miniconductance mechanosensitive channel MscM gene gene4311 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21590 SG48_RS21595 SG48_4238 psd psd 4381201 4382169 - phosphatidylserine decarboxylase proenzyme catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine gene gene4312 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21595 SG48_RS21600 SG48_4239 SG48_RS21600 4382266 4383318 - ribosome small subunit-dependent GTPase A EngC%3B RsgA%3B CpgA%3B circularly permuted GTPase%3B ribosome small subunit-dependent GTPase A%3B has the pattern G4-G1-G3 as opposed to other GTPases%3B interacts strongly with 30S ribosome which stimulates GTPase activity gene gene4313 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21600 SG48_RS21605 SG48_4240 SG48_RS21605 4383413 4383958 + oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene4314 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21605 SG48_RS21610 SG48_4241 SG48_RS21610 4384169 4384244 + tRNA-Gly tRNA gene4315 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21610 SG48_RS21615 SG48_4242 SG48_RS21615 4384281 4384356 + tRNA-Gly tRNA gene4316 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21615 SG48_RS21620 SG48_4243 SG48_RS21620 4384392 4384467 + tRNA-Gly tRNA gene4317 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21620 SG48_RS21625 SG48_4245 SG48_RS21625 4384737 4385876 - epoxyqueuosine reductase gene gene4318 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21625 SG48_RS21630 SG48_4246 SG48_RS21630 4385890 4387422 + carbohydrate kinase gene gene4319 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21630 SG48_RS21635 SG48_4247 SG48_RS21635 4387394 4387855 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE needed for nucleoid integrity%3B possibly involved in cell wall synthesis gene gene4320 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21635 SG48_RS21640 SG48_4248 SG48_RS21640 4387874 4389211 + N-acetylmuramoyl-L-alanine amidase gene gene4321 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21640 SG48_RS21645 SG48_4249 SG48_RS21645 4389221 4391068 + DNA mismatch repair protein MutL gene gene4322 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21645 SG48_RS21650 SG48_4250 miaA miaA 4391061 4392011 + tRNA dimethylallyltransferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene4323 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21650 SG48_RS21655 SG48_4251 hfq hfq 4392097 4392405 + RNA chaperone Hfq HF-I%2C host factor for RNA phage Q beta replication gene gene4324 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21655 SG48_RS21660 SG48_4252 SG48_RS21660 4392481 4393761 + GTPase HflX involved in modulation of proteins HflK and HflC%3B part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein gene gene4325 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21660 SG48_RS21665 SG48_4253 SG48_RS21665 4393847 4395106 + cell division protein FtsH with HflC inhibits proteolysis of lambda cII protein by FtsH gene gene4326 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21665 SG48_RS21670 SG48_4254 SG48_RS21670 4395109 4396113 + modulator of FtsH protease HflC with HflK inhibits proteolysis of lambda cII protein by FtsH gene gene4327 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21670 SG48_RS21675 SG48_4255 SG48_RS21675 4396195 4396392 + membrane protein gene gene4328 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21675 SG48_RS21680 SG48_4256 SG48_RS21680 4396496 4397794 + adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene4329 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21680 SG48_RS21685 SG48_4257 SG48_RS21685 4397999 4398424 + transcriptional regulator negatively regulates the transcription of genes upregulated by nitrosative stress gene gene4330 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21685 SG48_RS21690 SG48_4258 SG48_RS21690 4398463 4400904 + ribonuclease R 3'-5'exoribonuclease that acts nonspecifically on poly(A)%2C poly(U) and ribosomal RNAs gene gene4331 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21690 SG48_RS21695 SG48_4259 SG48_RS21695 4401084 4401815 + 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB Specifically methylates the ribose of guanosine 2251 in 23S rRNA gene gene4332 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21695 SG48_RS21700 SG48_4260 SG48_RS21700 4401942 4402343 + DUF2170 domain-containing protein gene gene4333 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21700 SG48_RS21705 SG48_4261 SG48_RS21705 4402362 4403060 + PspA/IM30 family protein gene gene4334 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21705 SG48_RS21710 SG48_4262 SG48_RS21710 4403111 4403770 + DUF2491 domain-containing protein gene gene4335 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21710 SG48_RS21715 SG48_4263 SG48_RS21715 4403788 4404186 + hypothetical protein gene gene4336 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21715 SG48_RS21720 SG48_4264 SG48_RS21720 4404196 4404834 + DUF1190 domain-containing protein gene gene4337 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21720 SG48_RS21725 SG48_4265 SG48_RS21725 4404837 4406000 + ATP-Grasp family ATPase gene gene4338 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21725 SG48_RS21730 SG48_4266 SG48_RS21730 4406084 4407709 + DNA alkylation damage repair protein catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA gene gene4339 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21730 SG48_RS21735 SG48_4267 SG48_RS21735 4407826 4408101 - DUF1471 domain-containing protein gene gene4340 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21735 SG48_RS21740 SG48_4268 SG48_RS21740 4408250 4408579 - lipoprotein BsmA in Escherichia coli%2C mutation of this gene affects biofilm maturation%2C stress response%2C and motility gene gene4341 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21740 SG48_RS21745 SG48_4269 SG48_RS21745 4408761 4409510 + esterase YjfP%3B esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro%3B unknown function and substrate in vivo gene gene4342 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21745 SG48_RS21750 SG48_4270 SG48_RS21750 4409507 4410262 - transcriptional regulator negative regulator of ulaG and ulaABCDEF gene gene4343 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21750 SG48_RS21755 SG48_4271 SG48_RS21755 4410370 4411434 - L-ascorbate-6-phosphate lactonase UlaG gene gene4344 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21755 SG48_RS21760 SG48_4272 SG48_RS21760 4411789 4413186 + ascorbate-specific permease IIC component UlaA gene gene4345 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21760 SG48_RS21765 SG48_4273 SG48_RS21765 4413202 4413507 + ascorbate-specific phosphotransferase enzyme IIB component involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene4346 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21765 SG48_RS21770 SG48_4274 SG48_RS21770 4413517 4413981 + ascorbate-specific phosphotransferase enzyme IIA component involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene4347 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21770 SG48_RS21775 SG48_4275 ulaD ulaD 4413995 4414645 + 3-keto-L-gulonate-6-phosphate decarboxylase ulaD catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization gene gene4348 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21775 SG48_RS21780 SG48_4276 SG48_RS21780 4414655 4415509 + L-ribulose-5-phosphate 3-epimerase UlaE gene gene4349 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21780 SG48_RS21785 SG48_4277 araD araD 4415509 4416195 + L-ribulose-5-phosphate 4-epimerase UlaF catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene4350 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21785 SG48_RS21790 SG48_4278 SG48_RS21790 4416325 4416600 - hypothetical protein gene gene4351 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21790 SG48_RS21795 SG48_RS21795 SG48_RS21795 4416684 4416803 + hypothetical protein gene gene4352 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21795 SG48_RS21800 SG48_4279 rpsF rpsF 4416927 4417322 + 30S ribosomal protein S6 binds cooperatively with S18 to the S15-16S complex%2C allowing platform assembly to continue with S11 and S21 gene gene4353 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21800 SG48_RS21805 SG48_4280 SG48_RS21805 4417329 4417643 + primosomal replication protein n binds single-stranded DNA at the primosome assembly site gene gene4354 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21805 SG48_RS21810 SG48_4281 rpsR rpsR 4417648 4417875 + 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene4355 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21810 SG48_RS21815 SG48_4282 rplI rplI 4417917 4418366 + 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene4356 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21815 SG48_RS21820 SG48_4283 SG48_RS21820 4418437 4419231 - hypothetical protein gene gene4357 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21820 SG48_RS21825 SG48_RS21825 SG48_RS21825 4419578 4419904 + hypothetical protein gene gene4358 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21825 SG48_RS21830 SG48_4285 SG48_RS21830 4419888 4420526 - OapA family protein gene gene4359 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21830 SG48_RS21835 SG48_4286 SG48_RS21835 4420744 4421364 + FKBP-type peptidyl-prolyl cis-trans isomerase FKBP-type%3B rotamase%3B catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides gene gene4360 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21835 SG48_RS21840 SG48_4287 SG48_RS21840 4421673 4423085 + D-serine/D-alanine/glycine transporter gene gene4361 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21840 SG48_RS21845 SG48_4288 SG48_RS21845 4423130 4423792 - iron-sulfur cluster repair protein YtfE Involved in anaerobic NO protection and iron metabolism gene gene4362 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21845 SG48_RS21850 SG48_4289 SG48_RS21850 4423900 4424865 - hypothetical protein gene gene4363 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21850 SG48_RS21855 SG48_4290 SG48_RS21855 4424973 4425833 - quinone oxidoreductase 2 gene gene4364 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21855 SG48_RS21860 SG48_4291 SG48_RS21860 4425832 4426302 + HxlR family transcriptional regulator gene gene4365 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21860 SG48_RS21865 SG48_4292 cpdB cpdB 4426431 4428374 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic enzyme%3B functions during ribonucleic acid degradation%3B 2'%2C3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate gene gene4366 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21865 SG48_RS21870 SG48_4293 SG48_RS21870 4428564 4429304 + 3'(2')%2C5'-bisphosphate nucleotidase CysQ catalyzes the formation of AMP from adenosine-3'%2C5'-bisphosphate gene gene4367 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21870 SG48_RS21875 SG48_4294 SG48_RS21875 4429516 4430454 + hypothetical protein gene gene4368 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21875 SG48_RS21880 SG48_4295 SG48_RS21880 4430517 4431071 - transcriptional regulator gene gene4369 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21880 SG48_RS21885 SG48_4296 SG48_RS21885 4431396 4431602 + DUF1107 domain-containing protein gene gene4370 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21885 SG48_RS21890 SG48_4297 SG48_RS21890 4431681 4433024 - hypothetical protein gene gene4371 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21890 SG48_RS21895 SG48_4298 SG48_RS21895 4433347 4433985 - peptide methionine sulfoxide reductase MsrA this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form%3B provides protection against oxidative stress gene gene4372 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21895 SG48_RS21900 SG48_RS21900 SG48_RS21900 4434093 4434221 + hypothetical protein gene gene4373 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21900 SG48_RS21905 SG48_4299 SG48_RS21905 4434191 4435924 + translocation and assembly module TamA gene gene4374 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21905 SG48_RS21910 SG48_4300 SG48_RS21910 4435921 4439700 + translocation and assembly module TamB gene gene4375 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21910 SG48_RS21915 SG48_4301 SG48_RS21915 4439703 4440044 + gamma-glutamylcyclotransferase YtfP gene gene4376 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21915 SG48_RS21920 SG48_4302 SG48_RS21920 4440256 4440507 + antitoxin ChpS part of the toxin-antitoxin ChpB-ChpS system gene gene4377 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21920 SG48_RS21925 SG48_4303 SG48_RS21925 4440501 4440851 + mRNA interferase ChpB toxin of the ChpB-ChpS toxin-antitoxin system gene gene4378 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21925 SG48_RS21930 SG48_4304 SG48_RS21930 4440931 4441461 - inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene4379 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21930 SG48_RS21935 SG48_4305 SG48_RS21935 4441771 4442727 + ABC transporter substrate-binding protein gene gene4380 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21935 SG48_RS21940 SG48_4306 SG48_RS21940 4442867 4444369 + sugar ABC transporter ATPase gene gene4381 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21940 SG48_RS21945 SG48_4307 SG48_RS21945 4444383 4445405 + sugar ABC transporter permease gene gene4382 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21945 SG48_RS21950 SG48_4308 SG48_RS21950 4445392 4446387 + ABC transporter permease membrane component of a putative sugar ABC transporter system gene gene4383 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21950 SG48_RS21955 SG48_4309 SG48_RS21955 4446420 4447418 - fructose 1%2C6-bisphosphatase catalyzes the formation of D-fructose 6-phosphate from fructose-1%2C6-bisphosphate gene gene4384 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21955 SG48_RS21960 SG48_4310 SG48_RS21960 4447594 4448967 + UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2%2C6-diaminoheptandioate ligase ligates L-alanyl-gamma-D-glutamyl-meso-diaminopimelate to UDP-N-acetylmuramic acid for reincorporation into peptidoglycan gene gene4385 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21960 SG48_RS21965 SG48_4311 SG48_RS21965 4449123 4449674 - ribosome-associated UPF0307 family protein gene gene4386 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21965 SG48_RS21970 SG48_4312 pmbA pmbA 4449768 4451120 + metalloprotease PmbA protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD gene gene4387 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21970 SG48_RS21975 SG48_RS21975 SG48_RS21975 4451299 4451664 + cytochrome B562 electron transport protein gene gene4388 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21975 SG48_RS21980 SG48_4314 SG48_RS21980 4451709 4452173 - anaerobic ribonucleoside-triphosphate reductase-activating protein activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions gene gene4389 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21980 SG48_RS21985 SG48_4315 SG48_RS21985 4452331 4454469 - anaerobic ribonucleoside-triphosphate reductase Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates gene gene4390 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21985 SG48_RS21990 SG48_4316 SG48_RS21990 4454863 4456518 - trehalose-6-phosphate hydrolase gene gene4391 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21990 SG48_RS21995 SG48_4317 SG48_RS21995 4456568 4457986 - PTS maltose transporter subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene4392 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS21995 SG48_RS22000 SG48_4318 treR treR 4458108 4459055 - transcriptional regulator regulates genes involved in trehalose metabolism%3B binds the intermediate trehalose-6-phosphate%3B binds a dimer%3B regulates treBC operon gene gene4393 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22000 SG48_RS22005 SG48_4320 SG48_RS22005 4459434 4462130 + magnesium-translocating P-type ATPase P-type%3B involved in magnesium transport into the cytoplasm gene gene4394 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22005 SG48_RS22010 SG48_4321 SG48_RS22010 4462336 4462722 - reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene4395 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22010 SG48_RS22015 SG48_4322 SG48_RS22015 4462795 4463256 - aspartate carbamoyltransferase regulatory chain involved in the allosteric regulation of aspartate carbamoyltransferase gene gene4396 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22015 SG48_RS22020 SG48_4323 SG48_RS22020 4463269 4464204 - aspartate carbamoyltransferase catalytic subunit gene gene4397 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22020 SG48_RS22025 SG48_4324 SG48_RS22025 4464208 4464342 - pyrBI operon leader peptide gene gene4398 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22025 SG48_RS22030 SG48_RS22030 SG48_RS22030 4464322 4464654 + hypothetical protein gene gene4399 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22030 SG48_RS22035 SG48_4325 SG48_RS22035 4464623 4465018 - endoribonuclease L-PSP gene gene4400 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22035 SG48_RS22040 SG48_4326 SG48_RS22040 4465149 4465862 - cyclic-di-GMP-binding biofilm dispersal mediator protein gene gene4401 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22040 SG48_RS22045 SG48_4327 SG48_RS22045 4465933 4466526 + transcriptional regulator gene gene4402 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22045 SG48_RS22050 SG48_4328 SG48_RS22050 4466671 4467123 + DUF386 domain-containing protein gene gene4403 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22050 SG48_RS22055 SG48_4329 SG48_RS22055 4467246 4469060 + SopA-central-domain-like hexapeptide repeat protein gene gene4404 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22055 SG48_RS22060 SG48_4330 SG48_RS22060 4469116 4470120 - ornithine carbamoyltransferase chain I catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene4405 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22060 SG48_RS22065 SG48_4331 SG48_RS22065 4470282 4470698 + regulator of ribonuclease activity B gene gene4406 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22065 SG48_RS22070 SG48_4332 SG48_RS22070 4470843 4471346 - GNAT family acetyltransferase gene gene4407 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22070 SG48_RS22075 SG48_4333 SG48_RS22075 4471539 4472735 + hypothetical protein gene gene4408 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22075 SG48_RS22080 SG48_4334 SG48_RS22080 4472791 4475646 - valine--tRNA ligase gene gene4409 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22080 SG48_RS22085 SG48_4335 SG48_RS22085 4475646 4476089 - DNA polymerase III subunit chi binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene4410 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22085 SG48_RS22090 SG48_4336 SG48_RS22090 4476249 4477760 - cytosol aminopeptidase catalyzes the removal of N-terminal amino acids preferably from various peptides%3B a cyteinylglycinase%2C transcription regulator and site-specific recombination factor gene gene4411 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22090 SG48_RS22095 SG48_4337 SG48_RS22095 4478027 4479127 + LPS export ABC transporter permease LptF with LptBGC is involved in lipopolysaccharide export gene gene4412 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22095 SG48_RS22100 SG48_4338 SG48_RS22100 4479127 4480209 + LPS export ABC transporter permease LptG with LptABCF is involved in the transport of lipopolysaccharides gene gene4413 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22100 SG48_RS22105 SG48_4339 SG48_RS22105 4480370 4481872 - DUF853 domain-containing protein gene gene4414 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22105 SG48_RS22110 SG48_4340 SG48_RS22110 4481950 4482948 - transcriptional regulator gene gene4415 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22110 SG48_RS22115 SG48_4341 SG48_RS22115 4483015 4484334 - gnt-II system L-idonate transporter gene gene4416 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22115 SG48_RS22120 SG48_4342 SG48_RS22120 4484396 4485160 - gluconate 5-dehydrogenase Involved in the nonphosphorylative%2C ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate gene gene4417 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22120 SG48_RS22125 SG48_4343 SG48_RS22125 4485184 4486215 - L-idonate 5-dehydrogenase (NAD(P)+) NAD-binding gene gene4418 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22125 SG48_RS22130 SG48_4344 idnK idnK 4486432 4486995 + thermosensitive gluconokinase gene gene4419 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22130 SG48_RS22135 SG48_4345 SG48_RS22135 4486999 4488018 - aldehyde reductase Ahr gene gene4420 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22135 SG48_RS22140 SG48_4346 SG48_RS22140 4488214 4488298 + tRNA-Leu tRNA gene4421 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22140 SG48_RS22145 SG48_RS22145 SG48_RS22145 4488559 4489749 + integrase gene gene4422 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22145 SG48_RS22150 SG48_4348 SG48_RS22150 4490081 4490446 + transposase represses IS2 gene transcription gene gene4423 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22150 SG48_RS22155 SG48_4349 SG48_RS22155 4490404 4491309 + integrase gene gene4424 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22155 SG48_RS22170 SG48_RS22170 SG48_RS22170 4492867 4493037 + hypothetical protein gene gene4426 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22170 SG48_RS22175 SG48_RS22175 SG48_RS22175 4493091 4493312 + hypothetical protein gene gene4427 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22175 SG48_RS22180 SG48_RS22180 SG48_RS22180 4493741 4493884 + hypothetical protein gene gene4428 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22180 SG48_RS22185 SG48_4352 SG48_RS22185 4493912 4495240 - transposase gene gene4429 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22185 SG48_RS22190 SG48_4353 SG48_RS22190 4495867 4497084 + MFS transporter membrane protein gene gene4430 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22190 SG48_RS22195 SG48_4354 SG48_RS22195 4497096 4498214 + oxidoreductase gene gene4431 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22195 SG48_RS22200 SG48_RS22200 SG48_RS22200 4498435 4498692 - hypothetical protein gene gene4432 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22200 SG48_RS22205 SG48_RS22205 SG48_RS22205 4498715 4498918 + hypothetical protein gene gene4433 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22205 SG48_RS22210 SG48_RS22210 SG48_RS22210 4499006 4499272 + transposase gene gene4434 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22210 SG48_RS22215 SG48_4359 SG48_RS22215 4499275 4500426 - transposase gene gene4435 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22215 SG48_RS22220 SG48_RS22220 SG48_RS22220 4500383 4500751 - transposase gene gene4436 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22220 SG48_RS22225 SG48_RS22225 SG48_RS22225 4500767 4501602 + transposase gene gene4437 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22225 SG48_RS22230 SG48_RS22230 SG48_RS22230 4501685 4501942 + transporter gene gene4438 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22230 SG48_RS22235 SG48_4362 SG48_RS22235 4502499 4503266 - Fe(3+) dicitrate transport ATP-binding protein FecE gene gene4439 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22235 SG48_RS22240 SG48_4363 fecD fecD 4503267 4504223 - Fe(3+) dicitrate ABC transporter permease Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter)%2C as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter. gene gene4440 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22240 SG48_RS22245 SG48_4364 fecC fecC 4504220 4505218 - Fe(3+) dicitrate ABC transporter permease part of the FecBCDE citrate-dependent iron (III) transport system gene gene4441 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22245 SG48_RS22250 SG48_4365 fecB fecB 4505215 4506117 - Fe(3+) dicitrate-binding periplasmic protein part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+) gene gene4442 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22250 SG48_RS22255 SG48_4366 SG48_RS22255 4506162 4508486 - fe(3+) dicitrate transporter fecA gene gene4443 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22255 SG48_RS22260 SG48_4367 SG48_RS22260 4508573 4509526 - protein FecR with FecA forms the FecAR signal transduction system%3B ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon gene gene4444 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22260 SG48_RS22265 SG48_4368 SG48_RS22265 4509523 4510044 - RNA polymerase sigma factor FecI Member of the extracytoplasmic function sigma factors which are active under specific conditions%3B binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription%3B this sigma factor regulates the genes for iron dicitrate transport gene gene4445 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22265 SG48_RS22270 SG48_RS22270 SG48_RS22270 4510255 4510455 - transposase gene gene4446 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22270 SG48_RS22275 SG48_RS22275 SG48_RS22275 4510530 4510823 + transposase gene gene4447 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22275 SG48_RS22280 SG48_RS22280 SG48_RS22280 4510824 4511033 + transposase gene gene4448 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22280 SG48_RS22285 SG48_4371 SG48_RS22285 4511147 4512133 - transcriptional regulator gene gene4449 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22285 SG48_RS22290 SG48_RS22290 SG48_RS22290 4512233 4512403 - hypothetical protein gene gene4450 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22290 SG48_RS22295 SG48_4372 SG48_RS22295 4512480 4513829 - transporter gene gene4451 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22295 SG48_RS22300 SG48_4373 SG48_RS22300 4513936 4515903 - dehydratase gene gene4452 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22300 SG48_RS22305 SG48_4374 SG48_RS22305 4515914 4516849 - 2-keto-3-deoxy-galactonate aldolase gene gene4453 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22305 SG48_RS22310 SG48_4375 SG48_RS22310 4516824 4517612 - transcriptional regulator gene gene4454 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22310 SG48_RS22315 SG48_4376 SG48_RS22315 4517915 4518697 - transcriptional regulator gene gene4455 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22315 SG48_RS22320 SG48_4377 SG48_RS22320 4518714 4519346 - protein SgcE gene gene4456 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22320 SG48_RS22325 SG48_4378 SG48_RS22325 4519358 4519789 - phosphotransferase enzyme IIA component gene gene4457 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22325 SG48_RS22330 SG48_4380 SG48_RS22330 4519920 4520726 - nucleoside triphosphatase gene gene4458 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22330 SG48_RS22335 SG48_4381 SG48_RS22335 4520739 4522052 - PTS system EIIC permease component gene gene4459 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22335 SG48_RS22340 SG48_4382 SG48_RS22340 4522064 4522345 - PTS sugar transporter subunit IIB gene gene4460 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22340 SG48_RS22345 SG48_4383 SG48_RS22345 4522339 4523460 - endoglucanase gene gene4461 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22345 SG48_RS22350 SG48_4385 SG48_RS22350 4524246 4524992 - methyltransferase gene gene4462 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22350 SG48_RS22355 SG48_4386 SG48_RS22355 4525048 4525593 - GNAT family acetyltransferase gene gene4463 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22355 SG48_RS22360 SG48_4387 SG48_RS22360 4525605 4525862 - hypothetical protein gene gene4464 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22360 SG48_RS22365 SG48_RS22365 SG48_RS22365 4526353 4526484 - hypothetical protein gene gene4465 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22365 SG48_RS22370 SG48_RS22370 SG48_RS22370 4526648 4526857 + DNA helicase superfamily I gene gene4466 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22370 SG48_RS22375 SG48_RS22375 SG48_RS22375 4526824 4527840 + hypothetical protein gene gene4467 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22375 SG48_RS22380 SG48_4390 SG48_RS22380 4528423 4529403 - 9-O-acetyl-N-acetylneuraminic acid deacetylase gene gene4468 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22380 SG48_RS22385 SG48_4391 SG48_RS22385 4529468 4530574 - N-acetylneuraminate epimerase gene gene4469 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22385 SG48_RS22390 SG48_RS22390 SG48_RS22390 4530594 4531142 - porin gene gene4470 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22390 SG48_RS22395 SG48_RS22395 SG48_RS22395 4531682 4531828 + hypothetical protein gene gene4471 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22395 SG48_RS22400 SG48_RS22400 SG48_RS22400 4532110 4532505 - hypothetical protein gene gene4472 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22400 SG48_RS22405 SG48_4393 SG48_RS22405 4532766 4533368 + type 1 fimbriae regulatory protein FimB gene gene4473 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22405 SG48_RS22410 SG48_4394 SG48_RS22410 4533846 4534442 + type 1 fimbriae regulatory protein FimE inversion of on/off regulator of fimA gene gene4474 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22410 SG48_RS22415 SG48_RS22415 SG48_RS22415 4534522 4534710 - hypothetical protein gene gene4475 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22415 SG48_RS22420 SG48_4395 fimA fimA 4534924 4535472 + type-1 fimbrial protein%2C A chain gene gene4476 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22420 SG48_RS22425 SG48_4396 SG48_RS22425 4535579 4536076 + fimbrin fimI gene gene4477 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22425 SG48_RS22430 SG48_4397 SG48_RS22430 4536113 4536838 + chaperone protein FimC gene gene4478 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22430 SG48_RS22435 SG48_4398 SG48_RS22435 4536905 4539541 + outer membrane usher protein FimD gene gene4479 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22435 SG48_RS22440 SG48_4399 SG48_RS22440 4539551 4540081 + protein FimF gene gene4480 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22440 SG48_RS22445 SG48_4400 SG48_RS22445 4540094 4540597 + protein FimG gene gene4481 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22445 SG48_RS22450 SG48_4401 SG48_RS22450 4540617 4541519 + protein FimH gene gene4482 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22450 SG48_RS22455 SG48_4402 SG48_RS22455 4541762 4543105 - gluconate transporter gene gene4483 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22455 SG48_RS22460 SG48_RS22460 SG48_RS22460 4543263 4543493 + hypothetical protein gene gene4484 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22460 SG48_RS22465 SG48_4403 SG48_RS22465 4543445 4544629 + mannonate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate gene gene4485 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22465 SG48_RS22470 SG48_4404 SG48_RS22470 4544710 4546170 + D-mannonate oxidoreductase gene gene4486 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22470 SG48_RS22475 SG48_RS22475 SG48_RS22475 4546192 4546386 - hypothetical protein gene gene4487 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22475 SG48_RS22480 SG48_4405 SG48_RS22480 4546385 4547158 + Uxu operon transcriptional regulator regulates the expression of uxuBA gene gene4488 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22480 SG48_RS22485 SG48_4406 SG48_RS22485 4547299 4548129 - hypothetical protein gene gene4489 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22485 SG48_RS22490 SG48_RS22490 SG48_RS22490 4548047 4548220 - hypothetical protein gene gene4490 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22490 SG48_RS22500 SG48_RS22500 SG48_RS22500 4548702 4548836 + hypothetical protein gene gene4491 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22500 SG48_RS22505 SG48_4407 iraD iraD 4548802 4549194 + anti-adapter protein IraD inhibitor of RssB activity in response to DNA damage%3B blocks degradation of stationary phase sigma factor RpoS gene gene4492 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22505 SG48_RS22510 SG48_4408 SG48_RS22510 4549187 4550098 - transcriptional regulator gene gene4493 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22510 SG48_RS22515 SG48_4409 SG48_RS22515 4550163 4551335 - isoaspartyl dipeptidase gene gene4494 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22515 SG48_RS22520 SG48_4410 SG48_RS22520 4551348 4551809 - hypothetical protein gene gene4495 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22520 SG48_RS22525 SG48_4411 SG48_RS22525 4551806 4552489 - nucleoside recognition pore and gate family inner membrane transporter gene gene4496 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22525 SG48_RS22530 SG48_4412 SG48_RS22530 4552739 4553293 + RNA 2'-phosphotransferase in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate%3B functions in tRNA splicing%3B the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown gene gene4497 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22530 SG48_RS22535 SG48_4413 SG48_RS22535 4553306 4554484 - DUF1228 family inner membrane MFS superfamily transporter gene gene4498 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22535 SG48_RS22540 SG48_4414 SG48_RS22540 4554552 4555412 - SdiA-regulated family membrane-anchored protein%3B phytase-like esterase gene gene4499 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22540 SG48_RS22545 SG48_RS22545 SG48_RS22545 4555477 4555734 - hypothetical protein gene gene4500 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22545 SG48_RS22550 SG48_4415 SG48_RS22550 4555731 4556498 - 2-hydroxyglutaryl-CoA dehydratase activator gene gene4501 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22550 SG48_RS22555 SG48_4416 SG48_RS22555 4556508 4557659 - 2-hydroxyglutaryl-CoA dehydratase gene gene4502 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22555 SG48_RS22560 SG48_4417 SG48_RS22560 4557775 4559055 - zinc-type alcohol dehydrogenase-like protein gene gene4503 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22560 SG48_RS22565 SG48_4418 SG48_RS22565 4559096 4560328 - multidrug resistance protein MdtM is involved in resistance to acriflavine%2C chloramphenicol%2C norfloxacin%2C ethidium bromide and TPP gene gene4504 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22565 SG48_RS22570 SG48_RS22570 SG48_RS22570 4560807 4561727 + hypothetical protein gene gene4505 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22570 SG48_RS22575 SG48_4420 SG48_RS22575 4561971 4563383 - transcriptional regulator gene gene4506 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22575 SG48_RS22580 SG48_4421 SG48_RS22580 4563560 4563724 + DUF1127 domain-containing protein gene gene4507 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22580 SG48_RS22585 SG48_RS22585 SG48_RS22585 4564175 4565740 + hypothetical protein gene gene4508 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22585 SG48_RS22590 SG48_RS22590 SG48_RS22590 4565944 4568664 + hypothetical protein gene gene4509 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22590 SG48_RS22595 SG48_4424 SG48_RS22595 4568721 4569797 - protein mcrC gene gene4510 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22595 SG48_RS22600 SG48_4425 SG48_RS22600 4569767 4571146 - 5-methylcytosine-specific restriction enzyme B McrB protein together with McrC forms the McrBC restriction system%3B recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines)%3B appears to act against 5-methylcytosine preceded by a purine residue gene gene4511 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22600 SG48_RS22605 SG48_4426 SG48_RS22605 4571308 4571649 - hypothetical protein involved in the degradation of RNA%3B may be involved in the recycling of RNA during the SOS response gene gene4512 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22605 SG48_RS22610 SG48_4428 SG48_RS22610 4571877 4573271 - type-1 restriction enzyme EcoKI specificity protein gene gene4513 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22610 SG48_RS22615 SG48_4429 SG48_RS22615 4573268 4574857 - type I restriction enzyme EcoKI M protein gene gene4514 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22615 SG48_RS22620 SG48_4430 SG48_RS22620 4575058 4578570 - type I restriction enzyme EcoKI R protein gene gene4515 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22620 SG48_RS22625 SG48_4431 SG48_RS22625 4578758 4579672 + Mrr restriction system protein gene gene4516 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22625 SG48_RS22630 SG48_4432 SG48_RS22630 4579718 4580674 - metal-binding GTPase gene gene4517 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22630 SG48_RS22635 SG48_4433 SG48_RS22635 4580685 4580888 - hypothetical protein gene gene4518 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22635 SG48_RS22640 SG48_4434 SG48_RS22640 4580938 4583088 - hypothetical protein gene gene4519 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22640 SG48_RS22645 SG48_RS22645 SG48_RS22645 4583133 4583306 - hypothetical protein gene gene4520 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22645 SG48_RS22650 SG48_4435 SG48_RS22650 4583466 4585121 + methyl-accepting chemotaxis protein I serine sensor receptor gene gene4521 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22650 SG48_RS22655 SG48_4436 SG48_RS22655 4585170 4586531 - L-galactonate transporter gene gene4522 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22655 SG48_RS22660 SG48_4437 SG48_RS22660 4586746 4587660 - transcriptional regulator gene gene4523 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22660 SG48_RS22665 SG48_4438 SG48_RS22665 4587799 4588821 + L-galactonate-5-dehydrogenase gene gene4524 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22665 SG48_RS22670 SG48_4439 SG48_RS22670 4588959 4591250 - phosphoglycerol transferase I catalyzes the transfer of phosphoglycerol to the glucan backbone gene gene4525 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22670 SG48_RS22675 SG48_4440 SG48_RS22675 4591504 4591995 - hypothetical protein gene gene4526 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22675 SG48_RS22680 SG48_4441 SG48_RS22680 4592047 4592784 - DNA replication protein DnaC acts to load the DnaB helicase onto the initiation site during DNA replication gene gene4527 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22680 SG48_RS22685 SG48_4442 SG48_RS22685 4592787 4593326 - primosomal protein 1 This protein is required for primosome-dependent normal DNA replication%3B it is also involved in inducing stable DNA replication during SOS response. It forms%2C in concert with dnaB protein and other prepriming proteins dnaC%2C N%2C N'%2C N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' gene gene4528 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22685 SG48_RS22690 SG48_4443 SG48_RS22690 4593433 4593906 - DUF3815 domain-containing protein gene gene4529 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22690 SG48_RS22695 SG48_4444 SG48_RS22695 4593897 4594667 - hypothetical protein gene gene4530 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22695 SG48_RS22700 SG48_4445 SG48_RS22700 4595286 4596011 + transcriptional regulator gene gene4531 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22700 SG48_RS22705 SG48_4446 SG48_RS22705 4595969 4596646 + transcriptional activator protein BglJ regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin gene gene4532 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22705 SG48_RS22710 SG48_4447 SG48_RS22710 4596684 4597472 - ferric iron reductase FhuF gene gene4533 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22710 SG48_RS22715 SG48_4448 SG48_RS22715 4597574 4597849 + hypothetical protein gene gene4534 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22715 SG48_RS22720 SG48_4449 SG48_RS22720 4597888 4597974 - tRNA-Leu tRNA gene4535 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22720 SG48_RS22725 SG48_4450 SG48_RS22725 4598009 4598095 - tRNA-Leu tRNA gene4536 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22725 SG48_RS22730 SG48_4451 SG48_RS22730 4598124 4598210 - tRNA-Leu tRNA gene4537 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22730 SG48_RS22735 SG48_4452 rsmC rsmC 4598478 4599509 - ribosomal RNA small subunit methyltransferase C 16S rRNA M2G1207 methyltransferase%3B one of many enzymes that modify bases of the ribosomal RNA%3B this enzyme methylates the G at position 1207 of the small ribosomal subunit gene gene4538 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22735 SG48_RS22740 SG48_4453 SG48_RS22740 4599612 4600025 + DNA polymerase III subunit psi with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene4539 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22740 SG48_RS22745 SG48_4454 rimI rimI 4599994 4600440 + ribosomal-protein-alanine acetyltransferase alanine acetyltransferase that specifically acetylates ribosomal protein S18 gene gene4540 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22745 SG48_RS22750 SG48_4455 SG48_RS22750 4600455 4601132 + pyrimidine 5'-nucleotidase YjjG manganese-dependent 5'-nucleotidase%3B specific for 5'-UMP%2C 5'-dUMP%2C and 5'-dTMP%3B member of haloacid dehalogenase (HAD)-like hydrolase superfamily gene gene4541 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22750 SG48_RS22755 SG48_4456 prfC prfC 4601223 4602812 + peptide chain release factor 3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred%3B GDP/GTP-binding protein gene gene4542 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22755 SG48_RS22760 SG48_4457 SG48_RS22760 4603205 4603810 + osmotically-inducible protein Y gene gene4543 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22760 SG48_RS22765 SG48_4458 SG48_RS22765 4603937 4604098 + hypothetical protein gene gene4544 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22765 SG48_RS22770 SG48_4459 SG48_RS22770 4604220 4605293 + patatin gene gene4545 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22770 SG48_RS22775 SG48_4460 SG48_RS22775 4605290 4606069 + DNase gene gene4546 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22775 SG48_RS22780 SG48_4461 SG48_RS22780 4606489 4607352 - glycine radical enzyme activase gene gene4547 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22780 SG48_RS22785 SG48_4462 SG48_RS22785 4607324 4608874 - DUF3029 domain-containing protein gene gene4548 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22785 SG48_RS22790 SG48_RS22790 SG48_RS22790 4608926 4609027 + hypothetical protein gene gene4549 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22790 SG48_RS22795 SG48_4463 SG48_RS22795 4609132 4609911 + deoxyribose-phosphate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate gene gene4550 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22795 SG48_RS22800 SG48_4464 SG48_RS22800 4610038 4611360 + thymidine phosphorylase gene gene4551 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22800 SG48_RS22805 SG48_4465 SG48_RS22805 4611412 4612635 + phosphopentomutase gene gene4552 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22805 SG48_RS22810 SG48_4466 deoD deoD 4612692 4613411 + purine nucleoside phosphorylase catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate gene gene4553 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22810 SG48_RS22815 SG48_4467 SG48_RS22815 4613578 4614909 + kinase gene gene4554 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22815 SG48_RS22820 SG48_4468 lplA lplA 4614910 4615926 - lipoate-protein ligase A Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins gene gene4555 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22820 SG48_RS22825 SG48_4469 SG48_RS22825 4615954 4616598 - protein Smp gene gene4556 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22825 SG48_RS22830 SG48_4470 serB serB 4616704 4617672 + phosphoserine phosphatase catalyzes the formation of serine from O-phosphoserine gene gene4557 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22830 SG48_RS22835 SG48_4471 SG48_RS22835 4617721 4619103 + DNA repair protein RadA Sms%3B stabilizes the strand-invasion intermediate during the DNA repair%3B involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents gene gene4558 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22835 SG48_RS22840 SG48_4472 SG48_RS22840 4619124 4620356 + trifunctional NAD biosynthesis/regulator protein NadR catalyzes the formation of NAD(+) from nicotinamide ribonucleotide%3B catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside%3B also has a regulatory function gene gene4559 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22840 SG48_RS22845 SG48_RS22845 SG48_RS22845 4620390 4620557 + transcriptional regulator gene gene4560 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22845 SG48_RS22850 SG48_4473 SG48_RS22850 4620664 4622331 - energy-dependent translational throttle protein EttA ChvD%3B in Agrobacterium tumefaciens%2C mutations in both Walker boxes were found to affect virulence gene gene4561 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22850 SG48_RS22855 SG48_4474 SG48_RS22855 4622542 4624479 + murein transglycosylase catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan gene gene4562 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22855 SG48_RS22860 SG48_4475 SG48_RS22860 4624569 4624895 + Trp operon repressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription gene gene4563 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22860 SG48_RS22865 SG48_4476 yjjX yjjX 4625042 4625554 - non-canonical purine NTP phosphatase pyrophosphatase%3B has activity against dUTP and dITP%3B the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226%3B in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms%3B in Escherichia coli overexpression of this gene leads to resistance to an HMP analog gene gene4564 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22865 SG48_RS22870 SG48_4477 SG48_RS22870 4625606 4626253 + phosphoglycerate mutase GpmB catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate gene gene4565 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22870 SG48_RS22875 SG48_4478 SG48_RS22875 4626250 4627119 - right origin-binding protein AraC family%3B binds to the right arm of the replication origin oriC gene gene4566 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22875 SG48_RS22880 SG48_4479 SG48_RS22880 4627330 4627803 + protein CreA gene gene4567 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22880 SG48_RS22885 SG48_4480 SG48_RS22885 4627816 4628505 + two-component system response regulator response regulator in two-component regulatory system with CreC%3B CreB protein is phosphorylated by sensor protein phospho-CreC%3B involved in catabolic regulation gene gene4568 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22885 SG48_RS22890 SG48_4481 SG48_RS22890 4628505 4629929 + two-component system sensor histidine kinase part of a two-component regulatory system with CreB or PhoB%3B involved in catabolic regulation gene gene4569 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22890 SG48_RS22895 SG48_4482 SG48_RS22895 4629987 4631339 + protein CreD gene gene4570 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22895 SG48_RS22900 SG48_4483 SG48_RS22900 4631399 4632115 - two-component system response regulator gene gene4571 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22900 SG48_RS22905 SG48_4484 SG48_RS22905 4632211 4632351 + hypothetical protein gene gene4572 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22905 SG48_RS22910 SG48_4485 SG48_RS22910 4632751 4633437 + methyltransferase member of the SPOUT superfamily of methyltransferases gene gene4573 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22910 SG48_RS22965 SG48_1184 SG48_RS22965 1218825 1221472 + autotransporter gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22965 SG48_RS22970 SG48_1385 SG48_RS22970 1417181 1417336 - hypothetical protein gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22970 SG48_RS22975 SG48_4350 SG48_RS22975 4491486 4492600 - phosphoethanolamine transferase YjgX gene gene4425 http://www.ncbi.nlm.nih.gov/gene/?term=SG48_RS22975