locus-tag	class	description
BU34_RS00010	COG0592	DNA-directed DNA polymerase activity
BU34_RS00020	COG0187	DNA topoisomerase II activity
BU34_RS00030	COG3753	Protein conserved in bacteria
BU34_RS00035	COG0561	phosphatase activity
BU34_RS00045	COG2186	Transcriptional regulator
BU34_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
BU34_RS00055	COG0800	Aldolase
BU34_RS00065	COG2271	Major facilitator Superfamily
BU34_RS00075	COG0823	Involved in the tonB-independent uptake of proteins
BU34_RS00080	COG5645	(Lipo)protein
BU34_RS00100	COG2188	Transcriptional regulator
BU34_RS00120	COG0675	Transposase, IS605 OrfB family
BU34_RS00125	COG2149	membrane
BU34_RS00135	COG0641	radical SAM
BU34_RS00140	COG2814	Major facilitator Superfamily
BU34_RS00160	COG0028	Belongs to the TPP enzyme family
BU34_RS00165	COG0440	acetolactate synthase activity
BU34_RS00170	COG2197	response regulator
BU34_RS00175	COG3851	Histidine kinase
BU34_RS00180	COG2271	Major facilitator Superfamily
BU34_RS00185	COG2271	Major facilitator Superfamily
BU34_RS00195	COG2252	PERMEase
BU34_RS00220	COG1464	Belongs to the NlpA lipoprotein family
BU34_RS00225	COG0697	spore germination
BU34_RS00230	COG2814	Major facilitator Superfamily
BU34_RS00245	COG2211	Major facilitator Superfamily
BU34_RS00250	COG1501	Belongs to the glycosyl hydrolase 31 family
BU34_RS00255	COG2982	Protein involved in outer membrane biogenesis
BU34_RS00260	COG2233	PERMEase
BU34_RS00265	COG0786	glutamate:sodium symporter activity
BU34_RS00270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BU34_RS00275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BU34_RS00280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BU34_RS00290	COG0194	GDP metabolic process
BU34_RS00300	COG2860	membrane
BU34_RS00310	COG1561	YicC-like family, N-terminal region
BU34_RS00335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BU34_RS00365	COG1519	Transferase
BU34_RS00370	COG0859	PFAM glycosyl transferase family 9
BU34_RS00375	COG0438	transferase activity, transferring glycosyl groups
BU34_RS00380	COG0515	serine threonine protein kinase
BU34_RS00390	COG2200	EAL domain
BU34_RS00395	COG0789	Transcriptional regulator
BU34_RS00400	COG5562	phage envelope protein
BU34_RS00415	COG0538	isocitrate dehydrogenase activity
BU34_RS00420	COG1187	pseudouridine synthase activity
BU34_RS00440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BU34_RS00445	COG0745	RESPONSE REGULATOR receiver
BU34_RS00450	COG2205	protein histidine kinase activity
BU34_RS00455	COG2850	peptidyl-arginine hydroxylation
BU34_RS00480	COG1177	transmembrane transport
BU34_RS00485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BU34_RS00495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BU34_RS00500	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BU34_RS00510	COG4591	ABC-type transport system involved in lipoprotein release permease component
BU34_RS00515	COG1136	(ABC) transporter
BU34_RS00520	COG4591	ABC-type transport system involved in lipoprotein release permease component
BU34_RS00530	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BU34_RS00535	COG1388	LysM domain
BU34_RS00535	COG1376	ErfK ybiS ycfS ynhG family protein
BU34_RS00545	COG1309	transcriptional regulator
BU34_RS00550	COG3134	Outer membrane lipoprotein
BU34_RS00555	COG1252	NADH dehydrogenase
BU34_RS00575	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BU34_RS00580	COG5633	Lipoprotein
BU34_RS00585	COG0537	adenosine 5'-monophosphoramidase activity
BU34_RS00590	COG4773	Receptor
BU34_RS00595	COG1263	PTS System
BU34_RS00595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS00600	COG0084	hydrolase, TatD family'
BU34_RS00605	COG0470	DNA polymerase III
BU34_RS00615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BU34_RS00620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BU34_RS00625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BU34_RS00635	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS00640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BU34_RS00660	COG1399	metal-binding, possibly nucleic acid-binding protein
BU34_RS00665	COG0424	maF-like protein
BU34_RS00670	COG0564	pseudouridine synthase activity
BU34_RS00680	COG1530	ribonuclease E activity
BU34_RS00685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BU34_RS00690	COG1256	bacterial-type flagellum assembly
BU34_RS00695	COG1705	Flagellar rod assembly protein muramidase FlgJ
BU34_RS00695	COG3951	Flagellar rod assembly protein muramidase FlgJ
BU34_RS00710	COG4786	Flagellar basal body rod
BU34_RS00715	COG4787	bacterial-type flagellum-dependent cell motility
BU34_RS00720	COG1749	Flagellar hook protein flgE
BU34_RS00725	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BU34_RS00730	COG1558	bacterial-type flagellum-dependent cell motility
BU34_RS00735	COG1815	bacterial-type flagellum-dependent cell motility
BU34_RS00740	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BU34_RS00745	COG2747	anti-sigma28 factor FlgM
BU34_RS00750	COG3418	PFAM FlgN family protein
BU34_RS00755	COG0728	peptidoglycan biosynthetic process
BU34_RS00760	COG0673	inositol 2-dehydrogenase activity
BU34_RS00770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BU34_RS00780	COG2999	glutathione oxidoreductase activity
BU34_RS00815	COG3038	cytochrome b561
BU34_RS00820	COG2353	YceI-like domain
BU34_RS00830	COG1560	Kdo2-lipid A biosynthetic process
BU34_RS00850	COG5645	(Lipo)protein
BU34_RS00855	COG2943	transferase activity, transferring hexosyl groups
BU34_RS00880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BU34_RS00885	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BU34_RS00895	COG1662	PFAM IS1 transposase
BU34_RS00925	COG2197	response regulator
BU34_RS00940	COG1462	curli production assembly transport component CsgG
BU34_RS00950	COG3381	protein complex oligomerization
BU34_RS00990	COG2801	Transposase and inactivated derivatives
BU34_RS00995	COG3706	GGDEF domain
BU34_RS01000	COG0457	Tetratricopeptide repeat
BU34_RS01005	COG0726	polysaccharide deacetylase
BU34_RS01005	COG1649	PFAM Uncharacterised BCR, COG1649
BU34_RS01010	COG1215	transferase activity, transferring glycosyl groups
BU34_RS01015	COG3658	cytochrome
BU34_RS01020	COG1702	phosphate starvation-inducible protein PhoH
BU34_RS01030	COG2837	iron assimilation
BU34_RS01035	COG2822	iron ion transport
BU34_RS01050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BU34_RS01060	COG0506	proline dehydrogenase activity
BU34_RS01060	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BU34_RS01060	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BU34_RS01065	COG1309	transcriptional regulator
BU34_RS01075	COG1335	isochorismatase
BU34_RS01100	COG2233	PERMEase
BU34_RS01105	COG3729	General stress protein
BU34_RS01150	COG0243	molybdopterin cofactor binding
BU34_RS01155	COG3005	denitrification pathway
BU34_RS01160	COG0745	RESPONSE REGULATOR receiver
BU34_RS01165	COG1879	ABC-type sugar transport system periplasmic component
BU34_RS01170	COG2205	protein histidine kinase activity
BU34_RS01170	COG2198	Histidine kinase
BU34_RS01170	COG0784	Response regulator, receiver
BU34_RS01175	COG0348	domain, Protein
BU34_RS01190	COG1278	Cold shock
BU34_RS01195	COG1278	Cold shock
BU34_RS01220	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BU34_RS01225	COG1596	polysaccharide export
BU34_RS01230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BU34_RS01235	COG0489	protein tyrosine kinase activity
BU34_RS01235	COG3206	protein involved in exopolysaccharide biosynthesis
BU34_RS01250	COG1294	oxidase, subunit
BU34_RS01255	COG1271	oxidase subunit
BU34_RS01260	COG1773	rubredoxin
BU34_RS01265	COG1999	signal sequence binding
BU34_RS01270	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BU34_RS01275	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BU34_RS01280	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BU34_RS01285	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BU34_RS01295	COG0670	Belongs to the BI1 family
BU34_RS01300	COG2920	part of a sulfur-relay system
BU34_RS01305	COG1254	Belongs to the acylphosphatase family
BU34_RS01320	COG1832	CoA-binding protein
BU34_RS01340	COG0210	DNA helicase
BU34_RS01345	COG3304	Inner membrane component domain
BU34_RS01350	COG1289	transmembrane transporter activity
BU34_RS01355	COG3070	regulator of competence-specific genes
BU34_RS01370	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BU34_RS01370	COG2885	chlorophyll binding
BU34_RS01380	COG1067	ATP-dependent peptidase activity
BU34_RS01390	COG3130	regulation of translation
BU34_RS01395	COG3009	Protein conserved in bacteria
BU34_RS01400	COG3008	intermembrane lipid transfer
BU34_RS01400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BU34_RS01405	COG2995	paraquat-inducible protein a
BU34_RS01410	COG0488	(ABC) transporter
BU34_RS01420	COG0633	Ferredoxin
BU34_RS01420	COG3217	Mosc domain protein beta barrel domain protein
BU34_RS01435	COG3121	Chaperone
BU34_RS01440	COG3539	Fimbrial protein
BU34_RS01445	COG3539	Fimbrial protein
BU34_RS01450	COG3539	Fimbrial protein
BU34_RS01455	COG3188	usher protein
BU34_RS01460	COG3121	Chaperone
BU34_RS01465	COG3539	Fimbrial protein
BU34_RS01470	COG0431	NADPH-dependent FMN reductase
BU34_RS01475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BU34_RS01485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BU34_RS01490	COG1116	anion transmembrane transporter activity
BU34_RS01495	COG0308	aminopeptidase N
BU34_RS01520	COG1448	Aminotransferase
BU34_RS01525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BU34_RS01530	COG3108	Peptidase M15
BU34_RS01535	COG2989	Protein conserved in bacteria
BU34_RS01545	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BU34_RS01555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BU34_RS01560	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BU34_RS01565	COG3173	Aminoglycoside phosphotransferase
BU34_RS01580	COG3214	Protein conserved in bacteria
BU34_RS01590	COG1132	(ABC) transporter
BU34_RS01595	COG0658	competence protein
BU34_RS01595	COG2333	competence protein COMEC
BU34_RS01605	COG0539	negative regulation of cytoplasmic translation
BU34_RS01615	COG0501	Belongs to the peptidase M48B family
BU34_RS01630	COG2323	membrane
BU34_RS01635	COG1944	ATP diphosphatase activity
BU34_RS01640	COG2116	formate transmembrane transporter activity
BU34_RS01645	COG1882	Formate acetyltransferase
BU34_RS01650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BU34_RS01655	COG2249	NAD(P)H dehydrogenase (quinone) activity
BU34_RS01660	COG0583	DNA-binding transcription factor activity
BU34_RS01665	COG0531	amino acid
BU34_RS01675	COG1335	isochorismatase
BU34_RS01680	COG3302	dmso reductase anchor subunit
BU34_RS01685	COG0437	4 iron, 4 sulfur cluster binding
BU34_RS01690	COG0243	molybdopterin cofactor binding
BU34_RS01700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BU34_RS01710	COG1674	ftsk spoiiie
BU34_RS01710	COG1178	ABC-type Fe3 transport system permease component
BU34_RS01715	COG1522	sequence-specific DNA binding
BU34_RS01720	COG0492	ferredoxin-NADP+ reductase activity
BU34_RS01725	COG4988	ABC transporter
BU34_RS01730	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BU34_RS01750	COG0542	response to heat
BU34_RS01760	COG1278	Cold shock
BU34_RS01765	COG1136	(ABC) transporter
BU34_RS01765	COG0577	efflux transmembrane transporter activity
BU34_RS01770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BU34_RS01775	COG2990	Protein conserved in bacteria
BU34_RS01780	COG3593	DNA synthesis involved in DNA repair
BU34_RS01795	COG2431	L-lysine efflux transmembrane transporter activity
BU34_RS01805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BU34_RS01810	COG0028	Belongs to the TPP enzyme family
BU34_RS01815	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BU34_RS01820	COG0702	epimerase
BU34_RS01825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BU34_RS01830	COG3023	N-Acetylmuramoyl-L-alanine amidase
BU34_RS01845	COG1126	abc transporter atp-binding protein
BU34_RS01850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BU34_RS01855	COG4215	(ABC) transporter
BU34_RS01860	COG4160	amino acid transport
BU34_RS01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BU34_RS01880	COG1177	transmembrane transport
BU34_RS01885	COG1176	ABC-type spermidine putrescine transport system, permease component I
BU34_RS01890	COG3842	ATPase activity
BU34_RS01895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BU34_RS01915	COG0778	Nitroreductase
BU34_RS01925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BU34_RS01940	COG3226	Transcriptional regulator
BU34_RS01945	COG0738	Major facilitator superfamily
BU34_RS01950	COG0561	phosphatase activity
BU34_RS01960	COG2814	Major facilitator Superfamily
BU34_RS01965	COG0671	phosphoesterase, PA-phosphatase related
BU34_RS01970	COG1349	DNA-binding transcription factor activity
BU34_RS01975	COG1686	Belongs to the peptidase S11 family
BU34_RS01980	COG0625	glutathione transferase activity
BU34_RS02000	COG2199	diguanylate cyclase activity
BU34_RS02005	COG2200	EAL domain
BU34_RS02020	COG0747	negative chemotaxis
BU34_RS02030	COG1446	asparaginase
BU34_RS02035	COG0303	'Molybdopterin
BU34_RS02040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BU34_RS02045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BU34_RS02050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BU34_RS02055	COG1882	Formate acetyltransferase
BU34_RS02060	COG0561	phosphatase activity
BU34_RS02070	COG0488	(ABC) transporter
BU34_RS02075	COG1376	ErfK ybiS ycfS ynhG family protein
BU34_RS02080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BU34_RS02085	COG1321	iron dependent repressor
BU34_RS02095	COG2194	sulfuric ester hydrolase activity
BU34_RS02100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BU34_RS02105	COG5006	permease, DMT superfamily
BU34_RS02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BU34_RS02125	COG0765	amino acid transport
BU34_RS02130	COG1126	abc transporter atp-binding protein
BU34_RS02135	COG0668	transmembrane transport
BU34_RS02150	COG4774	siderophore transport
BU34_RS02160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BU34_RS02170	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BU34_RS02175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BU34_RS02180	COG1199	ATP-dependent helicase activity
BU34_RS02185	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
BU34_RS02190	COG0513	Belongs to the DEAD box helicase family
BU34_RS02195	COG1309	transcriptional regulator
BU34_RS02205	COG1131	(ABC) transporter
BU34_RS02210	COG0842	Transport permease protein
BU34_RS02215	COG0842	Transport permease protein
BU34_RS02225	COG3568	Endonuclease Exonuclease Phosphatase
BU34_RS02230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BU34_RS02235	COG0392	lysyltransferase activity
BU34_RS02240	COG0670	Belongs to the BI1 family
BU34_RS02245	COG0670	Belongs to the BI1 family
BU34_RS02250	COG0314	molybdopterin synthase activity
BU34_RS02255	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BU34_RS02265	COG0521	Mo-molybdopterin cofactor biosynthetic process
BU34_RS02280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BU34_RS02290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BU34_RS02295	COG2226	methyltransferase
BU34_RS02310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BU34_RS02315	COG1881	PFAM PEBP family protein
BU34_RS02430	COG0494	nUDIX hydrolase
BU34_RS02520	COG0305	Participates in initiation and elongation during chromosome replication
BU34_RS02590	COG4712	double-strand break repair protein
BU34_RS02650	COG0582	viral genome integration into host DNA
BU34_RS02655	COG4677	pectinesterase activity
BU34_RS02660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BU34_RS02665	COG0471	metal ion transport
BU34_RS02670	COG2828	Protein conserved in bacteria
BU34_RS02675	COG0583	DNA-binding transcription factor activity
BU34_RS02685	COG0561	phosphatase activity
BU34_RS02690	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BU34_RS02695	COG4149	molybdate abc transporter
BU34_RS02700	COG0725	ABC transporter, periplasmic molybdate-binding protein
BU34_RS02710	COG2005	Transcriptional regulator
BU34_RS02710	COG3585	molybdate ion transport
BU34_RS02715	COG1119	ATPase activity
BU34_RS02720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BU34_RS02725	COG1085	galactose-1-phosphate uridylyltransferase
BU34_RS02735	COG2017	converts alpha-aldose to the beta-anomer
BU34_RS02745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BU34_RS02760	COG1230	cation diffusion facilitator family transporter
BU34_RS02765	COG3201	nicotinamide mononucleotide transporter
BU34_RS02810	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BU34_RS02815	COG2885	chlorophyll binding
BU34_RS02825	COG3064	Membrane
BU34_RS02830	COG0848	biopolymer transport protein
BU34_RS02835	COG0811	peptide transport
BU34_RS02840	COG0824	Thioesterase
BU34_RS02845	COG3790	cyd operon protein YbgE
BU34_RS02850	COG4890	Cyd operon protein YbgT
BU34_RS02855	COG1294	oxidase, subunit
BU34_RS02860	COG1271	oxidase subunit
BU34_RS02870	COG0383	alpha-mannosidase activity
BU34_RS02875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS02875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS02875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS02880	COG2188	Transcriptional regulator
BU34_RS02885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BU34_RS02895	COG0508	dehydrogenase complex catalyzes the overall conversion of
BU34_RS02900	COG0567	Dehydrogenase, E1 component
BU34_RS02910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BU34_RS02915	COG1053	succinate dehydrogenase
BU34_RS02920	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BU34_RS02925	COG2009	succinate dehydrogenase
BU34_RS02935	COG0372	Belongs to the citrate synthase family
BU34_RS02940	COG3539	Fimbrial protein
BU34_RS02945	COG3188	usher protein
BU34_RS02950	COG3121	Chaperone
BU34_RS02955	COG3539	Fimbrial protein
BU34_RS02960	COG3180	Ammonia monooxygenase
BU34_RS02975	COG1984	allophanate hydrolase subunit 2
BU34_RS02980	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BU34_RS02985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BU34_RS02990	COG3104	oligopeptide transport
BU34_RS02995	COG0415	Belongs to the DNA photolyase family
BU34_RS03000	COG3272	Protein of unknown function (DUF1722)
BU34_RS03005	COG5433	transposase activity
BU34_RS03015	COG5433	transposase activity
BU34_RS03025	COG3209	COG3209 Rhs family protein
BU34_RS03055	COG2205	protein histidine kinase activity
BU34_RS03060	COG0745	RESPONSE REGULATOR receiver
BU34_RS03070	COG1982	Orn Lys Arg decarboxylase major
BU34_RS03075	COG0531	amino acid
BU34_RS03095	COG0033	Phosphoglucomutase
BU34_RS03100	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BU34_RS03105	COG0596	Alpha beta hydrolase
BU34_RS03115	COG0716	FMN binding
BU34_RS03130	COG0735	belongs to the Fur family
BU34_RS03150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS03150	COG2190	(PTS) system
BU34_RS03150	COG1263	PTS System
BU34_RS03160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BU34_RS03165	COG1940	carbohydrate kinase activity
BU34_RS03165	COG1846	Transcriptional regulator
BU34_RS03170	COG0647	UMP catabolic process
BU34_RS03175	COG0367	asparagine synthase
BU34_RS03215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BU34_RS03225	COG1702	phosphate starvation-inducible protein PhoH
BU34_RS03235	COG4535	Mg2 and Co2 transporter CorC
BU34_RS03240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BU34_RS03250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BU34_RS03255	COG0765	amino acid transport
BU34_RS03260	COG0765	amino acid transport
BU34_RS03265	COG1126	abc transporter atp-binding protein
BU34_RS03275	COG0443	Heat shock 70 kDa protein
BU34_RS03280	COG2214	Heat shock protein DnaJ domain protein
BU34_RS03290	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BU34_RS03295	COG2214	Heat shock protein DnaJ domain protein
BU34_RS03305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BU34_RS03310	COG2888	peptidyl-tyrosine sulfation
BU34_RS03325	COG1466	dna polymerase III delta subunit
BU34_RS03335	COG0406	alpha-ribazole phosphatase activity
BU34_RS03340	COG0799	negative regulation of ribosome biogenesis
BU34_RS03350	COG0768	penicillin binding
BU34_RS03355	COG0772	Belongs to the SEDS family
BU34_RS03360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BU34_RS03365	COG1686	Belongs to the peptidase S11 family
BU34_RS03385	COG0583	DNA-binding transcription factor activity
BU34_RS03395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BU34_RS03400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BU34_RS03420	COG3069	C4-dicarboxylate transmembrane transporter activity
BU34_RS03425	COG4565	transcriptional regulatory protein
BU34_RS03430	COG3290	protein histidine kinase activity
BU34_RS03435	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BU34_RS03445	COG2301	Belongs to the HpcH HpaI aldolase family
BU34_RS03450	COG3051	citrate lyase alpha subunit
BU34_RS03465	COG0471	metal ion transport
BU34_RS03470	COG3719	Belongs to the RNase T2 family
BU34_RS03475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BU34_RS03485	COG1063	alcohol dehydrogenase
BU34_RS03490	COG0589	response to stress
BU34_RS03495	COG3634	alkyl hydroperoxide reductase activity
BU34_RS03500	COG0450	alkyl hydroperoxide reductase
BU34_RS03505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BU34_RS03510	COG0583	DNA-binding transcription factor activity
BU34_RS03515	COG3969	phosphoadenosine phosphosulfate
BU34_RS03520	COG1475	DNA binding
BU34_RS03525	COG0436	Aminotransferase
BU34_RS03530	COG0371	Dehydrogenase
BU34_RS03535	COG2879	small protein
BU34_RS03540	COG1966	Carbon starvation protein
BU34_RS03545	COG2050	protein possibly involved in aromatic compounds catabolism
BU34_RS03550	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS03555	COG3433	isochorismatase activity
BU34_RS03555	COG1535	isochorismatase
BU34_RS03560	COG1021	2,3-dihydroxybenzoate-AMP ligase
BU34_RS03565	COG1169	isochorismate synthase
BU34_RS03570	COG4592	Periplasmic binding protein
BU34_RS03580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BU34_RS03585	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BU34_RS03590	COG1120	ATPase activity
BU34_RS03595	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BU34_RS03600	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BU34_RS03600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BU34_RS03605	COG3251	PFAM MbtH domain protein
BU34_RS03610	COG2382	esterase
BU34_RS03615	COG4771	TonB-dependent receptor
BU34_RS03620	COG2977	Belongs to the P-Pant transferase superfamily
BU34_RS03625	COG3385	transposase activity
BU34_RS03650	COG2315	Protein conserved in bacteria
BU34_RS03655	COG0778	Nitroreductase
BU34_RS03660	COG0668	transmembrane transport
BU34_RS03665	COG1113	amino acid transport
BU34_RS03670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BU34_RS03675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BU34_RS03680	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BU34_RS03685	COG1538	Outer membrane efflux protein
BU34_RS03690	COG0745	RESPONSE REGULATOR receiver
BU34_RS03695	COG5002	protein histidine kinase activity
BU34_RS03710	COG3209	COG3209 Rhs family protein
BU34_RS03710	COG4104	PAAR repeat-containing protein
BU34_RS03730	COG5433	transposase activity
BU34_RS03740	COG4783	chaperone-mediated protein folding
BU34_RS03750	COG2207	Transcriptional regulator
BU34_RS03760	COG2197	response regulator
BU34_RS03765	COG3539	Fimbrial protein
BU34_RS03770	COG3539	Fimbrial protein
BU34_RS03775	COG3188	usher protein
BU34_RS03780	COG3121	Chaperone
BU34_RS03785	COG3539	Fimbrial protein
BU34_RS03795	COG2501	S4 domain
BU34_RS03800	COG1988	membrane-bound metal-dependent
BU34_RS03810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BU34_RS03820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BU34_RS03825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BU34_RS03830	COG0549	Belongs to the carbamate kinase family
BU34_RS03840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BU34_RS03845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BU34_RS03850	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BU34_RS03855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BU34_RS03860	COG3257	ureidoglycine aminohydrolase activity
BU34_RS03865	COG1929	Belongs to the glycerate kinase type-1 family
BU34_RS03870	COG2233	PERMEase
BU34_RS03880	COG1953	Uracil, thiamine, allantoin
BU34_RS03885	COG2084	Dehydrogenase
BU34_RS03890	COG3622	Belongs to the hyi family
BU34_RS03895	COG3960	tartronate-semialdehyde synthase activity
BU34_RS03900	COG1414	Transcriptional regulator
BU34_RS03910	COG0583	DNA-binding transcription factor activity
BU34_RS03920	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BU34_RS03925	COG4181	ATPase activity
BU34_RS03930	COG2755	lipolytic protein G-D-S-L family
BU34_RS03935	COG0300	oxidoreductase activity
BU34_RS03940	COG3118	belongs to the thioredoxin family
BU34_RS03945	COG0390	transport system, permease component
BU34_RS03950	COG4619	ABC transporter
BU34_RS03955	COG0330	HflC and HflK could
BU34_RS03960	COG1585	Membrane protein implicated in regulation of membrane protease activity
BU34_RS03965	COG0789	Transcriptional regulator
BU34_RS03970	COG0531	amino acid
BU34_RS03980	COG2217	Heavy metal translocating P-type atpase
BU34_RS03985	COG3093	addiction module antidote protein HigA
BU34_RS03990	COG3735	TraB family
BU34_RS03995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BU34_RS04000	COG0737	Belongs to the 5'-nucleotidase family
BU34_RS04005	COG2223	nitrite transmembrane transporter activity
BU34_RS04010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BU34_RS04010	COG4651	solute:proton antiporter activity
BU34_RS04015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BU34_RS04050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BU34_RS04060	COG2832	Protein of unknown function (DUF454)
BU34_RS04065	COG3923	Primosomal replication protein n
BU34_RS04080	COG1196	nuclear chromosome segregation
BU34_RS04080	COG3264	Mechanosensitive ion channel
BU34_RS04085	COG1309	transcriptional regulator
BU34_RS04090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BU34_RS04095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BU34_RS04110	COG0110	maltose O-acetyltransferase activity
BU34_RS04120	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BU34_RS04125	COG5507	3-demethylubiquinone-9 3-methyltransferase
BU34_RS04130	COG3695	enzyme binding
BU34_RS04135	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BU34_RS04140	COG1946	Acyl-CoA thioesterase
BU34_RS04145	COG0004	ammonium transporteR
BU34_RS04150	COG0347	Belongs to the P(II) protein family
BU34_RS04155	COG1132	(ABC) transporter
BU34_RS04160	COG1132	(ABC) transporter
BU34_RS04165	COG1522	sequence-specific DNA binding
BU34_RS04175	COG4533	DNA binding
BU34_RS04185	COG0824	Thioesterase
BU34_RS04190	COG1555	photosystem II stabilization
BU34_RS04195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BU34_RS04200	COG0776	regulation of translation
BU34_RS04205	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BU34_RS04230	COG0271	Belongs to the BolA IbaG family
BU34_RS04235	COG3056	Lipoprotein
BU34_RS04240	COG2223	nitrite transmembrane transporter activity
BU34_RS04245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BU34_RS04250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BU34_RS04255	COG1845	cytochrome c oxidase, subunit III
BU34_RS04260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BU34_RS04270	COG2814	Major facilitator Superfamily
BU34_RS04280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BU34_RS04285	COG0693	protein deglycase activity
BU34_RS04300	COG0142	geranyltranstransferase activity
BU34_RS04310	COG0667	Aldo Keto reductase
BU34_RS04315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BU34_RS04320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BU34_RS04335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BU34_RS04335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BU34_RS04345	COG4238	major outer membrane lipoprotein
BU34_RS04350	COG3248	Nucleoside-binding outer membrane protein
BU34_RS04360	COG1403	HNH endonuclease
BU34_RS04365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BU34_RS04370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BU34_RS04375	COG1862	Preprotein translocase
BU34_RS04395	COG0366	Alpha amylase catalytic
BU34_RS04400	COG1113	amino acid transport
BU34_RS04405	COG1114	Component of the transport system for branched-chain amino acids
BU34_RS04410	COG5002	protein histidine kinase activity
BU34_RS04415	COG0745	RESPONSE REGULATOR receiver
BU34_RS04420	COG0420	3'-5' exonuclease activity
BU34_RS04425	COG0419	ATPase involved in DNA repair
BU34_RS04430	COG2814	Major facilitator Superfamily
BU34_RS04435	COG1940	carbohydrate kinase activity
BU34_RS04455	COG4126	flavin adenine dinucleotide binding
BU34_RS04480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BU34_RS04485	COG3706	GGDEF domain
BU34_RS04495	COG1785	Belongs to the alkaline phosphatase family
BU34_RS04510	COG1181	Belongs to the D-alanine--D-alanine ligase family
BU34_RS04530	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BU34_RS04540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BU34_RS04545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BU34_RS04550	COG3468	outer membrane autotransporter barrel domain protein
BU34_RS04555	COG0113	porphobilinogen synthase activity
BU34_RS04560	COG2175	clavaminate synthase activity
BU34_RS04565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BU34_RS04575	COG4521	taurine ABC transporter
BU34_RS04580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BU34_RS04585	COG1215	transferase activity, transferring glycosyl groups
BU34_RS04615	COG3122	Protein conserved in bacteria
BU34_RS04620	COG2814	Major facilitator Superfamily
BU34_RS04635	COG3971	2-oxopent-4-enoate hydratase activity
BU34_RS04655	COG1414	Transcriptional regulator
BU34_RS04660	COG1609	Transcriptional regulator
BU34_RS04665	COG3250	beta-galactosidase activity
BU34_RS04670	COG2223	nitrite transmembrane transporter activity
BU34_RS04675	COG0110	maltose O-acetyltransferase activity
BU34_RS04680	COG2807	transmembrane transport
BU34_RS04690	COG0288	reversible hydration of carbon dioxide
BU34_RS04695	COG0583	DNA-binding transcription factor activity
BU34_RS04700	COG0402	S-adenosylhomocysteine deaminase activity
BU34_RS04705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BU34_RS04710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BU34_RS04715	COG2079	MmgE PrpD family protein
BU34_RS04720	COG0372	Belongs to the citrate synthase family
BU34_RS04725	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BU34_RS04730	COG3829	transcription factor binding
BU34_RS04740	COG1280	lysine exporter protein (LysE YggA)
BU34_RS04755	COG1064	alcohol dehydrogenase
BU34_RS04760	COG0402	S-adenosylhomocysteine deaminase activity
BU34_RS04765	COG0549	Belongs to the carbamate kinase family
BU34_RS04775	COG1304	FMN binding
BU34_RS04780	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BU34_RS04790	COG0666	response to abiotic stimulus
BU34_RS04800	COG0583	DNA-binding transcription factor activity
BU34_RS04805	COG2200	EAL domain
BU34_RS04805	COG2771	luxR family
BU34_RS04815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BU34_RS04845	COG1556	Lactate utilization protein
BU34_RS04850	COG1139	Iron-sulfur cluster binding protein
BU34_RS04855	COG0247	lactate metabolic process
BU34_RS04860	COG2207	Transcriptional regulator
BU34_RS04865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BU34_RS04875	COG3059	membrane
BU34_RS04880	COG3708	Transcriptional regulator
BU34_RS04880	COG2207	Transcriptional regulator
BU34_RS04885	COG1388	LysM domain
BU34_RS04925	COG3188	usher protein
BU34_RS04935	COG3121	Chaperone
BU34_RS04940	COG0727	PFAM Uncharacterised protein family (UPF0153)
BU34_RS04945	COG3477	response to acidic pH
BU34_RS04950	COG2080	2 iron, 2 sulfur cluster binding
BU34_RS04955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BU34_RS04960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BU34_RS04965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BU34_RS04970	COG0583	DNA-binding transcription factor activity
BU34_RS05010	COG4626	Terminase
BU34_RS05010	COG1802	Transcriptional regulator
BU34_RS05065	COG1403	HNH endonuclease
BU34_RS05090	COG1846	Transcriptional regulator
BU34_RS05130	COG5532	Uncharacterized conserved protein (DUF2303)
BU34_RS05135	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BU34_RS05150	COG0582	viral genome integration into host DNA
BU34_RS05170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BU34_RS05190	COG2195	Cleaves the N-terminal amino acid of tripeptides
BU34_RS05195	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BU34_RS05200	COG1690	Belongs to the RtcB family
BU34_RS05205	COG0454	-acetyltransferase
BU34_RS05215	COG2161	toxin-antitoxin pair type II binding
BU34_RS05230	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BU34_RS05235	COG1191	sigma factor activity
BU34_RS05260	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BU34_RS05265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BU34_RS05280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BU34_RS05305	COG4786	Flagellar basal body rod
BU34_RS05310	COG4787	bacterial-type flagellum-dependent cell motility
BU34_RS05315	COG1749	Flagellar hook protein flgE
BU34_RS05325	COG1558	bacterial-type flagellum-dependent cell motility
BU34_RS05330	COG1815	bacterial-type flagellum-dependent cell motility
BU34_RS05360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BU34_RS05380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BU34_RS05390	COG1677	Flagellar hook-basal body complex protein FliE
BU34_RS05415	COG1987	bacterial-type flagellum assembly
BU34_RS05435	COG1943	Transposase
BU34_RS05440	COG0791	NLP P60 protein
BU34_RS05445	COG3034	peptidoglycan biosynthetic process
BU34_RS05450	COG0121	glutamine amidotransferase
BU34_RS05460	COG1960	acyl-CoA dehydrogenase activity
BU34_RS05470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BU34_RS05475	COG5433	transposase activity
BU34_RS05485	COG3209	COG3209 Rhs family protein
BU34_RS05500	COG3157	Type VI secretion system effector, Hcp
BU34_RS05505	COG4104	PAAR repeat-containing protein
BU34_RS05525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BU34_RS05535	COG2226	methyltransferase
BU34_RS05545	COG0741	lytic transglycosylase activity
BU34_RS05545	COG1388	LysM domain
BU34_RS05550	COG2226	methyltransferase
BU34_RS05560	COG0583	DNA-binding transcription factor activity
BU34_RS05565	COG0656	L-ascorbic acid biosynthetic process
BU34_RS05600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BU34_RS05605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BU34_RS05610	COG2011	ABC-type metal ion transport system permease component
BU34_RS05615	COG1464	Belongs to the NlpA lipoprotein family
BU34_RS05625	COG1720	tRNA m6t6A37 methyltransferase activity
BU34_RS05635	COG0791	NLP P60 protein
BU34_RS05640	COG3015	lipoprotein NlpE involved in copper resistance
BU34_RS05645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BU34_RS05650	COG4681	YaeQ
BU34_RS05660	COG4568	rho-dependent transcription termination
BU34_RS05670	COG0346	lactoylglutathione lyase activity
BU34_RS05675	COG1982	Orn Lys Arg decarboxylase major
BU34_RS05685	COG0587	DNA-directed DNA polymerase activity
BU34_RS05710	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BU34_RS05715	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BU34_RS05725	COG0750	zinc metalloprotease
BU34_RS05730	COG0575	Belongs to the CDS family
BU34_RS05735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BU34_RS05740	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BU34_RS05765	COG0024	Methionine aminopeptidase
BU34_RS05780	COG1408	metallophosphoesterase
BU34_RS05790	COG3835	regulator
BU34_RS05795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BU34_RS05810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BU34_RS05815	COG2860	membrane
BU34_RS05835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BU34_RS05840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BU34_RS05845	COG1120	ATPase activity
BU34_RS05850	COG4774	siderophore transport
BU34_RS05855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BU34_RS05865	COG1643	Atp-dependent helicase
BU34_RS05870	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BU34_RS05880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BU34_RS05890	COG0617	tRNA 3'-terminal CCA addition
BU34_RS05895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BU34_RS05900	COG1662	PFAM IS1 transposase
BU34_RS05905	COG3539	Fimbrial protein
BU34_RS05910	COG3539	Fimbrial protein
BU34_RS05935	COG5464	transposase or invertase
BU34_RS05945	COG0726	polysaccharide deacetylase
BU34_RS05950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS05955	COG0842	Transport permease protein
BU34_RS05960	COG1131	(ABC) transporter
BU34_RS05965	COG0288	reversible hydration of carbon dioxide
BU34_RS05970	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BU34_RS05975	COG4993	Dehydrogenase
BU34_RS05980	COG2132	Multicopper oxidase
BU34_RS06005	COG1049	propionate catabolic process, 2-methylcitrate cycle
BU34_RS06010	COG3064	Membrane
BU34_RS06015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BU34_RS06020	COG0508	dehydrogenase complex catalyzes the overall conversion of
BU34_RS06025	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BU34_RS06030	COG2186	Transcriptional regulator
BU34_RS06040	COG3725	Membrane protein required for beta-lactamase induction
BU34_RS06045	COG3023	N-Acetylmuramoyl-L-alanine amidase
BU34_RS06050	COG0157	Belongs to the NadC ModD family
BU34_RS06060	COG4969	Belongs to the N-Me-Phe pilin family
BU34_RS06065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BU34_RS06070	COG1459	type II secretion system
BU34_RS06080	COG0237	dephospho-CoA kinase activity
BU34_RS06100	COG0494	nUDIX hydrolase
BU34_RS06120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BU34_RS06125	COG0849	cell division
BU34_RS06130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BU34_RS06135	COG1181	Belongs to the D-alanine--D-alanine ligase family
BU34_RS06150	COG0772	Belongs to the SEDS family
BU34_RS06155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BU34_RS06165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BU34_RS06170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BU34_RS06175	COG0768	penicillin binding
BU34_RS06180	COG3116	cell division
BU34_RS06195	COG1609	Transcriptional regulator
BU34_RS06205	COG0440	acetolactate synthase activity
BU34_RS06210	COG0028	Belongs to the TPP enzyme family
BU34_RS06215	COG0583	DNA-binding transcription factor activity
BU34_RS06230	COG0473	3-isopropylmalate dehydrogenase activity
BU34_RS06245	COG2814	Major facilitator Superfamily
BU34_RS06255	COG4533	DNA binding
BU34_RS06260	COG4143	(ABC) transporter
BU34_RS06265	COG1178	ABC-type Fe3 transport system permease component
BU34_RS06275	COG0586	Pfam SNARE associated Golgi protein
BU34_RS06280	COG4977	sequence-specific DNA binding
BU34_RS06295	COG0235	Class ii aldolase
BU34_RS06300	COG0417	DNA replication proofreading
BU34_RS06310	COG0564	pseudouridine synthase activity
BU34_RS06315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BU34_RS06320	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BU34_RS06325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BU34_RS06350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BU34_RS06365	COG2271	Major facilitator Superfamily
BU34_RS06370	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BU34_RS06375	COG0644	oxidoreductase
BU34_RS06445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BU34_RS06450	COG0505	Belongs to the CarA family
BU34_RS06480	COG1047	Peptidyl-prolyl cis-trans
BU34_RS06495	COG0196	riboflavin kinase activity
BU34_RS06515	COG1662	PFAM IS1 transposase
BU34_RS06520	COG1662	PFAM IS1 transposase
BU34_RS06525	COG3188	usher protein
BU34_RS06535	COG0583	DNA-binding transcription factor activity
BU34_RS06545	COG2963	transposase activity
BU34_RS06550	COG2801	Transposase and inactivated derivatives
BU34_RS06560	COG3385	transposase activity
BU34_RS06580	COG4735	regulation of single-species biofilm formation
BU34_RS06585	COG1584	GPR1 FUN34 yaaH family protein
BU34_RS06590	COG0521	Mo-molybdopterin cofactor biosynthetic process
BU34_RS06600	COG1115	amino acid carrier protein
BU34_RS06620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BU34_RS06630	COG0460	homoserine dehydrogenase
BU34_RS06630	COG0527	aspartate kinase activity
BU34_RS06640	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BU34_RS06650	COG0745	RESPONSE REGULATOR receiver
BU34_RS06660	COG2205	protein histidine kinase activity
BU34_RS06665	COG0745	RESPONSE REGULATOR receiver
BU34_RS06670	COG3045	CreA protein
BU34_RS06675	COG3708	Transcriptional regulator
BU34_RS06675	COG2207	Transcriptional regulator
BU34_RS06695	COG0741	lytic transglycosylase activity
BU34_RS06700	COG0488	(ABC) transporter
BU34_RS06710	COG1056	cytidyltransferase-related domain
BU34_RS06710	COG3172	ATPase kinase involved in NAD metabolism
BU34_RS06715	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BU34_RS06720	COG0560	Phosphoserine phosphatase
BU34_RS06725	COG3726	membrane protein affecting hemolysin expression
BU34_RS06765	COG1328	CTP reductase activity
BU34_RS06770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BU34_RS06775	COG0084	hydrolase, TatD family'
BU34_RS06780	COG4667	esterase of the alpha-beta hydrolase superfamily
BU34_RS06790	COG2823	Periplasmic or secreted lipoprotein
BU34_RS06800	COG1011	Hydrolase
BU34_RS06805	COG0456	acetyltransferase
BU34_RS06810	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BU34_RS06845	COG4114	ferric iron reductase
BU34_RS06850	COG2197	response regulator
BU34_RS06855	COG2197	response regulator
BU34_RS06860	COG2966	Psort location CytoplasmicMembrane, score
BU34_RS06875	COG1484	DNA-dependent DNA replication
BU34_RS06890	COG1063	alcohol dehydrogenase
BU34_RS06895	COG1802	Transcriptional regulator
BU34_RS06900	COG2271	Major facilitator Superfamily
BU34_RS06905	COG0840	transmembrane signaling receptor activity
BU34_RS06910	COG1846	Transcriptional regulator
BU34_RS06915	COG0179	Fumarylacetoacetate (FAA) hydrolase
BU34_RS06920	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS06925	COG3384	dioxygenase
BU34_RS06935	COG3971	2-oxopent-4-enoate hydratase activity
BU34_RS06955	COG2368	4-hydroxyphenylacetate
BU34_RS06960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BU34_RS06970	COG1966	Carbon starvation protein
BU34_RS06975	COG2879	small protein
BU34_RS06980	COG0523	cobalamin synthesis protein
BU34_RS06985	COG1662	PFAM IS1 transposase
BU34_RS06990	COG2814	Major facilitator Superfamily
BU34_RS06995	COG2733	membrane
BU34_RS07005	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BU34_RS07010	COG1924	4 iron, 4 sulfur cluster binding
BU34_RS07025	COG0477	Major facilitator Superfamily
BU34_RS07035	COG3366	ferrous iron transmembrane transporter activity
BU34_RS07040	COG0700	Nucleoside recognition
BU34_RS07045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BU34_RS07050	COG0583	DNA-binding transcription factor activity
BU34_RS07075	COG2186	Transcriptional regulator
BU34_RS07085	COG0246	Mannitol dehydrogenase
BU34_RS07100	COG2610	gluconate transmembrane transporter activity
BU34_RS07105	COG3539	Fimbrial protein
BU34_RS07135	COG1662	PFAM IS1 transposase
BU34_RS07145	COG1595	DNA-templated transcription, initiation
BU34_RS07150	COG3712	iron ion homeostasis
BU34_RS07155	COG4772	TonB-dependent receptor
BU34_RS07160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BU34_RS07165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BU34_RS07170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BU34_RS07175	COG1120	ATPase activity
BU34_RS07180	COG2085	NADP oxidoreductase coenzyme F420-dependent
BU34_RS07195	COG3436	PFAM IS66 Orf2 family protein
BU34_RS07200	COG4372	Transposase
BU34_RS07205	COG2826	transposase and inactivated derivatives, IS30 family
BU34_RS07215	COG1662	PFAM IS1 transposase
BU34_RS07260	COG3842	ATPase activity
BU34_RS07265	COG2040	homocysteine
BU34_RS07270	COG0833	amino acid
BU34_RS07275	COG3039	Transposase
BU34_RS07380	COG2826	transposase and inactivated derivatives, IS30 family
BU34_RS07385	COG2801	Transposase and inactivated derivatives
BU34_RS07405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BU34_RS07490	COG3385	transposase activity
BU34_RS07555	COG1475	DNA binding
BU34_RS07850	COG5001	Diguanylate cyclase
BU34_RS07850	COG3300	MHYT domain
BU34_RS07895	COG1662	PFAM IS1 transposase
BU34_RS07895	COG3677	Transposase
BU34_RS07900	COG1662	PFAM IS1 transposase
BU34_RS07930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BU34_RS07950	COG0697	spore germination
BU34_RS07965	COG1595	DNA-templated transcription, initiation
BU34_RS07970	COG3712	iron ion homeostasis
BU34_RS07975	COG4772	TonB-dependent receptor
BU34_RS07980	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BU34_RS07985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BU34_RS07990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BU34_RS07995	COG1120	ATPase activity
BU34_RS08005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BU34_RS08010	COG0842	Transport permease protein
BU34_RS08010	COG1129	ABC transporter
BU34_RS08015	COG0842	Transport permease protein
BU34_RS08020	COG5433	transposase activity
BU34_RS08035	COG3209	COG3209 Rhs family protein
BU34_RS08045	COG1124	(ABC) transporter
BU34_RS08050	COG0444	Belongs to the ABC transporter superfamily
BU34_RS08055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BU34_RS08060	COG0601	transmembrane transport
BU34_RS08065	COG0747	negative chemotaxis
BU34_RS08070	COG2091	lysine biosynthetic process via aminoadipic acid
BU34_RS08075	COG0628	permease
BU34_RS08080	COG0477	Major facilitator Superfamily
BU34_RS08090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BU34_RS08105	COG3714	YhhN family
BU34_RS08115	COG3776	membrane
BU34_RS08120	COG0742	ribosomal rna small subunit methyltransferase
BU34_RS08125	COG0552	protein localization to endoplasmic reticulum
BU34_RS08130	COG2884	Cell division ATP-binding protein ftsE
BU34_RS08135	COG2177	Part of the ABC transporter FtsEX involved in
BU34_RS08140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BU34_RS08145	COG0683	leucine binding
BU34_RS08155	COG0456	acetyltransferase
BU34_RS08160	COG0683	leucine binding
BU34_RS08165	COG0559	Belongs to the binding-protein-dependent transport system permease family
BU34_RS08170	COG4177	L-phenylalanine transmembrane transporter activity
BU34_RS08175	COG0411	ABC transporter
BU34_RS08180	COG0410	ABC transporter
BU34_RS08190	COG1653	transport
BU34_RS08195	COG1175	transmembrane transport
BU34_RS08200	COG0395	ABC-type sugar transport system, permease component
BU34_RS08205	COG3842	ATPase activity
BU34_RS08210	COG0584	glycerophosphoryl diester phosphodiesterase
BU34_RS08220	COG0405	Gamma-glutamyltransferase
BU34_RS08235	COG3157	Type VI secretion system effector, Hcp
BU34_RS08240	COG1247	-acetyltransferase
BU34_RS08245	COG0673	inositol 2-dehydrogenase activity
BU34_RS08250	COG1741	Belongs to the pirin family
BU34_RS08255	COG1609	Transcriptional regulator
BU34_RS08260	COG3265	gluconokinase activity
BU34_RS08265	COG2610	gluconate transmembrane transporter activity
BU34_RS08270	COG2095	MarC family integral membrane protein
BU34_RS08275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BU34_RS08300	COG0058	SHG alpha-glucan phosphorylase activity
BU34_RS08305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BU34_RS08325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BU34_RS08340	COG1349	DNA-binding transcription factor activity
BU34_RS08345	COG4650	regulator
BU34_RS08350	COG1690	Belongs to the RtcB family
BU34_RS08365	COG0058	SHG alpha-glucan phosphorylase activity
BU34_RS08370	COG1640	4-alpha-glucanotransferase
BU34_RS08375	COG2610	gluconate transmembrane transporter activity
BU34_RS08395	COG5464	transposase or invertase
BU34_RS08405	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BU34_RS08410	COG1918	ferrous iron import across plasma membrane
BU34_RS08415	COG2183	response to ionizing radiation
BU34_RS08420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BU34_RS08445	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BU34_RS08455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BU34_RS08460	COG1011	Hydrolase
BU34_RS08470	COG0494	nUDIX hydrolase
BU34_RS08475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BU34_RS08480	COG4972	Pilus assembly protein
BU34_RS08485	COG3166	PFAM Fimbrial assembly family protein
BU34_RS08500	COG4796	Type ii and iii secretion system protein
BU34_RS08515	COG3266	domain, Protein
BU34_RS08520	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BU34_RS08525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BU34_RS08530	COG0546	phosphoglycolate phosphatase activity
BU34_RS08535	COG0180	Tryptophanyl-tRNA synthetase
BU34_RS08540	COG2188	Transcriptional regulator
BU34_RS08550	COG3457	Alanine racemase
BU34_RS08555	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BU34_RS08560	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BU34_RS08575	COG0626	cystathionine gamma-synthase activity
BU34_RS08580	COG2188	Transcriptional regulator
BU34_RS08585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BU34_RS08590	COG1082	Xylose isomerase domain protein TIM barrel
BU34_RS08595	COG2222	sugar isomerase
BU34_RS08600	COG0531	amino acid
BU34_RS08615	COG2116	formate transmembrane transporter activity
BU34_RS08620	COG2146	nitrite reductase [NAD(P)H] activity
BU34_RS08625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BU34_RS08635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BU34_RS08645	COG2184	nucleotidyltransferase activity
BU34_RS08650	COG0512	Glutamine amidotransferase of anthranilate synthase
BU34_RS08655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BU34_RS08660	COG1289	transmembrane transporter activity
BU34_RS08665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BU34_RS08675	COG1765	OsmC-like protein
BU34_RS08680	COG3954	Phosphoribulokinase
BU34_RS08690	COG0429	hydrolase of the alpha beta-hydrolase fold
BU34_RS08695	COG0488	(ABC) transporter
BU34_RS08710	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BU34_RS08715	COG1047	Peptidyl-prolyl cis-trans
BU34_RS08725	COG0545	Peptidyl-prolyl cis-trans isomerase
BU34_RS08730	COG2964	Protein conserved in bacteria
BU34_RS08770	COG3979	chitinase
BU34_RS08775	COG2906	2 iron, 2 sulfur cluster binding
BU34_RS08780	COG2193	ferroxidase activity
BU34_RS08785	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BU34_RS08790	COG1662	PFAM IS1 transposase
BU34_RS08795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BU34_RS08800	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BU34_RS08805	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BU34_RS08810	COG3156	type II secretion system protein K
BU34_RS08815	COG4795	General secretion pathway protein
BU34_RS08820	COG2165	general secretion pathway protein
BU34_RS08825	COG2165	general secretion pathway protein
BU34_RS08830	COG2165	general secretion pathway protein
BU34_RS08835	COG1459	type II secretion system
BU34_RS08845	COG1450	Type ii and iii secretion system protein
BU34_RS08850	COG3031	protein transport across the cell outer membrane
BU34_RS08855	COG3409	Peptidoglycan-binding domain 1 protein
BU34_RS08855	COG3267	Type II secretory pathway component ExeA
BU34_RS08880	COG0089	rRNA binding
BU34_RS08970	COG0201	protein transport
BU34_RS09010	COG0789	Transcriptional regulator
BU34_RS09015	COG3036	rescue of stalled ribosome
BU34_RS09025	COG0569	domain protein
BU34_RS09045	COG0758	DNA mediated transformation
BU34_RS09055	COG0551	DNA topoisomerase type I activity
BU34_RS09075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BU34_RS09115	COG1126	abc transporter atp-binding protein
BU34_RS09120	COG0765	amino acid transport
BU34_RS09125	COG4597	amino acid ABC transporter
BU34_RS09130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BU34_RS09145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BU34_RS09150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BU34_RS09155	COG1309	transcriptional regulator
BU34_RS09165	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BU34_RS09175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BU34_RS09185	COG4145	pantothenate transmembrane transporter activity
BU34_RS09190	COG3924	membrane
BU34_RS09195	COG0439	Biotin carboxylase
BU34_RS09200	COG0511	ligase activity, forming carbon-carbon bonds
BU34_RS09220	COG0604	alcohol dehydrogenase
BU34_RS09225	COG2200	EAL domain
BU34_RS09225	COG2199	diguanylate cyclase activity
BU34_RS09235	COG1077	Cell shape determining protein MreB Mrl
BU34_RS09240	COG1792	Involved in formation and maintenance of cell shape
BU34_RS09245	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BU34_RS09255	COG1530	ribonuclease E activity
BU34_RS09260	COG3164	Protein of unknown function
BU34_RS09265	COG0312	modulator of DNA gyrase
BU34_RS09270	COG0583	DNA-binding transcription factor activity
BU34_RS09290	COG2732	(Barnase) inhibitor
BU34_RS09310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BU34_RS09315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BU34_RS09320	COG3105	Protein conserved in bacteria
BU34_RS09325	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BU34_RS09340	COG0625	glutathione transferase activity
BU34_RS09345	COG2969	positive regulation of protein catabolic process
BU34_RS09350	COG3069	C4-dicarboxylate transmembrane transporter activity
BU34_RS09380	COG2731	YhcH YjgK YiaL family protein
BU34_RS09390	COG4804	nuclease activity
BU34_RS09395	COG0493	'glutamate synthase
BU34_RS09400	COG0067	glutamate synthase
BU34_RS09400	COG0070	glutamate synthase
BU34_RS09400	COG0069	glutamate synthase activity
BU34_RS09405	COG1242	4 iron, 4 sulfur cluster binding
BU34_RS09410	COG0784	Response regulator, receiver
BU34_RS09410	COG2198	Histidine kinase
BU34_RS09410	COG5002	protein histidine kinase activity
BU34_RS09415	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BU34_RS09425	COG0515	serine threonine protein kinase
BU34_RS09430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS09445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BU34_RS09450	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BU34_RS09455	COG1137	ATPase activity
BU34_RS09460	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BU34_RS09465	COG3117	lipopolysaccharide transmembrane transporter activity
BU34_RS09470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BU34_RS09475	COG0517	IMP dehydrogenase activity
BU34_RS09475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BU34_RS09480	COG0530	calcium, potassium:sodium antiporter activity
BU34_RS09485	COG1127	ABC transporter
BU34_RS09490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BU34_RS09495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BU34_RS09500	COG2854	intermembrane phospholipid transfer
BU34_RS09505	COG3113	response to antibiotic
BU34_RS09510	COG5007	Belongs to the BolA IbaG family
BU34_RS09520	COG3423	Transcriptional regulator
BU34_RS09525	COG0142	geranyltranstransferase activity
BU34_RS09540	COG0697	spore germination
BU34_RS09550	COG2027	D-alanyl-D-alanine carboxypeptidase
BU34_RS09555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BU34_RS09560	COG1534	Rna-binding protein
BU34_RS09570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BU34_RS09575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BU34_RS09585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BU34_RS09595	COG2194	sulfuric ester hydrolase activity
BU34_RS09615	COG0195	Participates in both transcription termination and antitermination
BU34_RS09650	COG0513	Belongs to the DEAD box helicase family
BU34_RS09660	COG0814	amino acid
BU34_RS09665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BU34_RS09670	COG0826	peptidase U32
BU34_RS09675	COG0826	peptidase U32
BU34_RS09680	COG3154	lipid carrier protein
BU34_RS09685	COG3153	acetyltransferase
BU34_RS09700	COG0693	protein deglycase activity
BU34_RS09705	COG0702	epimerase
BU34_RS09710	COG0701	Predicted permease
BU34_RS09715	COG2823	Periplasmic or secreted lipoprotein
BU34_RS09730	COG3107	peptidoglycan biosynthetic process
BU34_RS09735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BU34_RS09740	COG3539	Fimbrial protein
BU34_RS09745	COG3188	usher protein
BU34_RS09750	COG3121	Chaperone
BU34_RS09755	COG3539	Fimbrial protein
BU34_RS09760	COG0363	glucosamine-6-phosphate deaminase activity
BU34_RS09765	COG3716	PTS system mannose fructose sorbose family IID component
BU34_RS09770	COG3715	PTS system
BU34_RS09775	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS09785	COG2222	sugar isomerase
BU34_RS09790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BU34_RS09795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS09800	COG3716	PTS system mannose fructose sorbose family IID component
BU34_RS09810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS09820	COG1349	DNA-binding transcription factor activity
BU34_RS09830	COG2002	toxin-antitoxin pair type II binding
BU34_RS09835	COG2721	sulfolactate sulfo-lyase activity
BU34_RS09840	COG2271	Major facilitator Superfamily
BU34_RS09850	COG2084	Dehydrogenase
BU34_RS09855	COG1929	Belongs to the glycerate kinase type-1 family
BU34_RS09875	COG0583	DNA-binding transcription factor activity
BU34_RS09880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BU34_RS09890	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BU34_RS09895	COG1882	Formate acetyltransferase
BU34_RS09900	COG0251	oxidation-reduction process
BU34_RS09905	COG1760	l-serine dehydratase
BU34_RS09910	COG0814	amino acid
BU34_RS09925	COG1741	Belongs to the pirin family
BU34_RS09930	COG0583	DNA-binding transcription factor activity
BU34_RS09935	COG3152	Membrane
BU34_RS09940	COG3152	Membrane
BU34_RS09945	COG0435	Glutathione S-transferase
BU34_RS09950	COG2259	Doxx family
BU34_RS09960	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BU34_RS09965	COG4575	ribosome binding
BU34_RS09970	COG1422	Protein of unknown function (DUF1090)
BU34_RS09980	COG0586	Pfam SNARE associated Golgi protein
BU34_RS09985	COG2186	Transcriptional regulator
BU34_RS10010	COG2271	Major facilitator Superfamily
BU34_RS10020	COG2721	sulfolactate sulfo-lyase activity
BU34_RS10030	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BU34_RS10035	COG0861	Integral membrane protein TerC family
BU34_RS10040	COG0673	inositol 2-dehydrogenase activity
BU34_RS10045	COG2949	membrane
BU34_RS10050	COG1451	nucleotide metabolic process
BU34_RS10065	COG4680	protein conserved in bacteria
BU34_RS10070	COG5499	transcription regulator containing HTH domain
BU34_RS10075	COG1902	pentaerythritol trinitrate reductase activity
BU34_RS10075	COG0446	pyridine nucleotide-disulphide oxidoreductase
BU34_RS10080	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BU34_RS10080	COG3408	Glycogen debranching enzyme
BU34_RS10090	COG0531	amino acid
BU34_RS10095	COG2731	YhcH YjgK YiaL family protein
BU34_RS10100	COG3250	beta-galactosidase activity
BU34_RS10105	COG1609	Transcriptional regulator
BU34_RS10110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BU34_RS10120	COG0840	transmembrane signaling receptor activity
BU34_RS10125	COG1695	Transcriptional regulator
BU34_RS10130	COG2375	cellular response to nickel ion
BU34_RS10145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BU34_RS10150	COG0358	DNA primase activity
BU34_RS10155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BU34_RS10165	COG0471	metal ion transport
BU34_RS10170	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BU34_RS10175	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BU34_RS10180	COG0583	DNA-binding transcription factor activity
BU34_RS10190	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BU34_RS10205	COG4991	sh3 domain protein
BU34_RS10215	COG3025	triphosphatase activity
BU34_RS10240	COG2268	Band 7 protein
BU34_RS10245	COG1585	Membrane protein implicated in regulation of membrane protease activity
BU34_RS10255	COG3539	Fimbrial protein
BU34_RS10260	COG3121	Chaperone
BU34_RS10265	COG3188	usher protein
BU34_RS10270	COG3539	Fimbrial protein
BU34_RS10275	COG2960	long-chain fatty acid transporting porin activity
BU34_RS10295	COG3384	dioxygenase
BU34_RS10300	COG0754	glutathionylspermidine amidase activity
BU34_RS10315	COG1538	Outer membrane efflux protein
BU34_RS10320	COG0494	nUDIX hydrolase
BU34_RS10325	COG3151	Protein conserved in bacteria
BU34_RS10330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BU34_RS10335	COG3150	esterase
BU34_RS10340	COG0187	DNA topoisomerase II activity
BU34_RS10345	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BU34_RS10350	COG2249	NAD(P)H dehydrogenase (quinone) activity
BU34_RS10360	COG0642	Histidine kinase
BU34_RS10365	COG0745	RESPONSE REGULATOR receiver
BU34_RS10370	COG3111	PFAM Bacterial OB fold (BOF) protein
BU34_RS10375	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BU34_RS10385	COG2944	sequence-specific DNA binding
BU34_RS10390	COG4166	transmembrane transport
BU34_RS10395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BU34_RS10400	COG0204	Acyl-transferase
BU34_RS10405	COG2132	Multicopper oxidase
BU34_RS10410	COG1032	radical SAM domain protein
BU34_RS10415	COG4238	major outer membrane lipoprotein
BU34_RS10425	COG0656	L-ascorbic acid biosynthetic process
BU34_RS10430	COG1979	alcohol dehydrogenase
BU34_RS10435	COG1979	alcohol dehydrogenase
BU34_RS10445	COG2207	Transcriptional regulator
BU34_RS10450	COG0586	Pfam SNARE associated Golgi protein
BU34_RS10455	COG0626	cystathionine gamma-synthase activity
BU34_RS10465	COG0811	peptide transport
BU34_RS10470	COG0848	biopolymer transport protein
BU34_RS10475	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS10485	COG0667	Aldo Keto reductase
BU34_RS10505	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BU34_RS10510	COG0437	4 iron, 4 sulfur cluster binding
BU34_RS10515	COG5557	Pfam Polysulphide reductase, NrfD
BU34_RS10520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BU34_RS10525	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BU34_RS10530	COG1773	rubredoxin
BU34_RS10540	COG0298	carbon dioxide binding
BU34_RS10545	COG0625	glutathione transferase activity
BU34_RS10550	COG0754	glutathionylspermidine amidase activity
BU34_RS10555	COG0306	phosphate transporter
BU34_RS10560	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BU34_RS10565	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BU34_RS10570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BU34_RS10575	COG2244	polysaccharide biosynthetic process
BU34_RS10585	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BU34_RS10590	COG0795	lipopolysaccharide-transporting ATPase activity
BU34_RS10600	COG0156	8-amino-7-oxononanoate synthase activity
BU34_RS10605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BU34_RS10615	COG0318	PFAM AMP-dependent synthetase and ligase
BU34_RS10620	COG0456	acetyltransferase
BU34_RS10625	COG2186	Transcriptional regulator
BU34_RS10630	COG0277	FAD linked oxidase domain protein
BU34_RS10635	COG0277	FAD linked oxidase domain protein
BU34_RS10640	COG0247	lactate metabolic process
BU34_RS10645	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BU34_RS10650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BU34_RS10655	COG1620	l-lactate permease
BU34_RS10690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BU34_RS10695	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BU34_RS10705	COG1811	Na channel or pump
BU34_RS10710	COG1982	Orn Lys Arg decarboxylase major
BU34_RS10715	COG2211	Major facilitator Superfamily
BU34_RS10730	COG1194	a g-specific adenine glycosylase
BU34_RS10740	COG3171	Protein conserved in bacteria
BU34_RS10755	COG0252	asparaginase activity
BU34_RS10765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BU34_RS10780	COG0762	integral membrane protein
BU34_RS10785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BU34_RS10790	COG2805	Type II/IV secretion system protein
BU34_RS10805	COG0189	ligase activity
BU34_RS10810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BU34_RS10815	COG2356	endonuclease I
BU34_RS10825	COG2814	Major facilitator Superfamily
BU34_RS10850	COG1166	arginine decarboxylase activity
BU34_RS10860	COG0501	Belongs to the peptidase M48B family
BU34_RS10865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BU34_RS10870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS10875	COG2213	PTS system mannitol-specific
BU34_RS10880	COG1063	alcohol dehydrogenase
BU34_RS10885	COG1494	fructose-1,6-bisphosphatase
BU34_RS10890	COG3722	fumarate hydratase activity
BU34_RS10895	COG1072	(Pantothenic acid kinase))
BU34_RS10910	COG0191	fructose-bisphosphate aldolase activity
BU34_RS10915	COG0668	transmembrane transport
BU34_RS10920	COG1279	arginine transmembrane transporter activity
BU34_RS10925	COG2968	Membrane
BU34_RS10930	COG0583	DNA-binding transcription factor activity
BU34_RS10935	COG0427	acetyl-CoA hydrolase
BU34_RS10940	COG1024	Enoyl-CoA hydratase
BU34_RS10945	COG1703	isobutyryl-CoA mutase activity
BU34_RS10950	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BU34_RS10950	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BU34_RS10970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BU34_RS10975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BU34_RS10990	COG0006	proline dipeptidase activity
BU34_RS10995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BU34_RS11000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BU34_RS11020	COG2723	6-phospho-beta-galactosidase activity
BU34_RS11030	COG1272	protein, Hemolysin III
BU34_RS11040	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BU34_RS11050	COG0716	FMN binding
BU34_RS11055	COG4974	Belongs to the 'phage' integrase family
BU34_RS11060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BU34_RS11065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BU34_RS11075	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BU34_RS11090	COG2233	PERMEase
BU34_RS11100	COG0493	'glutamate synthase
BU34_RS11100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS11105	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS11110	COG2252	PERMEase
BU34_RS11115	COG0402	S-adenosylhomocysteine deaminase activity
BU34_RS11130	COG2233	PERMEase
BU34_RS11135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BU34_RS11135	COG2080	2 iron, 2 sulfur cluster binding
BU34_RS11140	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BU34_RS11145	COG0402	S-adenosylhomocysteine deaminase activity
BU34_RS11150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS11150	COG0493	'glutamate synthase
BU34_RS11155	COG2068	MobA-Related Protein
BU34_RS11160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BU34_RS11170	COG0549	Belongs to the carbamate kinase family
BU34_RS11180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BU34_RS11185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BU34_RS11190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BU34_RS11195	COG3829	transcription factor binding
BU34_RS11200	COG2080	2 iron, 2 sulfur cluster binding
BU34_RS11205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BU34_RS11210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BU34_RS11215	COG4942	peptidase
BU34_RS11225	COG3387	PFAM Glycoside hydrolase 15-related
BU34_RS11230	COG3387	PFAM Glycoside hydrolase 15-related
BU34_RS11275	COG3710	Transcriptional regulator
BU34_RS11280	COG2771	luxR family
BU34_RS11285	COG0814	amino acid
BU34_RS11290	COG0183	Belongs to the thiolase family
BU34_RS11300	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS11305	COG2814	Major facilitator Superfamily
BU34_RS11310	COG1794	racemase activity, acting on amino acids and derivatives
BU34_RS11315	COG0583	DNA-binding transcription factor activity
BU34_RS11325	COG1609	Transcriptional regulator
BU34_RS11340	COG0667	Aldo Keto reductase
BU34_RS11350	COG0861	Integral membrane protein TerC family
BU34_RS11375	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BU34_RS11390	COG2165	general secretion pathway protein
BU34_RS11395	COG4795	General secretion pathway protein
BU34_RS11405	COG4967	type IV pilus modification protein PilV
BU34_RS11410	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BU34_RS11420	COG1074	ATP-dependent DNA helicase activity
BU34_RS11425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BU34_RS11430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BU34_RS11430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BU34_RS11435	COG0860	N-Acetylmuramoyl-L-alanine amidase
BU34_RS11455	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BU34_RS11460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BU34_RS11465	COG2166	iron-sulfur cluster assembly
BU34_RS11470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BU34_RS11480	COG0583	DNA-binding transcription factor activity
BU34_RS11485	COG2363	Small membrane protein
BU34_RS11495	COG1349	DNA-binding transcription factor activity
BU34_RS11505	COG1070	Carbohydrate kinase
BU34_RS11515	COG0738	Major facilitator superfamily
BU34_RS11520	COG0235	Class ii aldolase
BU34_RS11525	COG1454	alcohol dehydrogenase
BU34_RS11535	COG1760	l-serine dehydratase
BU34_RS11540	COG0814	amino acid
BU34_RS11545	COG1611	Belongs to the LOG family
BU34_RS11565	COG3098	single-species biofilm formation
BU34_RS11570	COG0564	pseudouridine synthase activity
BU34_RS11575	COG0716	FMN binding
BU34_RS11580	COG2271	Major facilitator Superfamily
BU34_RS11585	COG4948	Mandelate Racemase Muconate Lactonizing
BU34_RS11590	COG2205	protein histidine kinase activity
BU34_RS11590	COG3437	response regulator, receiver
BU34_RS11590	COG3850	Histidine kinase
BU34_RS11590	COG4999	Histidine kinase
BU34_RS11595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BU34_RS11600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BU34_RS11605	COG2336	PFAM SpoVT AbrB
BU34_RS11610	COG2337	Toxic component of a toxin-antitoxin (TA) module
BU34_RS11615	COG3956	TIGRFAM MazG family protein
BU34_RS11630	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BU34_RS11640	COG0602	queuosine metabolic process
BU34_RS11645	COG1070	Carbohydrate kinase
BU34_RS11650	COG2223	nitrite transmembrane transporter activity
BU34_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS11660	COG0277	FAD linked oxidase domain protein
BU34_RS11665	COG0477	Major facilitator Superfamily
BU34_RS11670	COG2086	electron transfer activity
BU34_RS11675	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BU34_RS11680	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BU34_RS11685	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BU34_RS11690	COG0644	oxidoreductase
BU34_RS11695	COG0720	synthase
BU34_RS11715	COG1203	CRISPR-associated helicase, Cas3
BU34_RS11725	COG2801	Transposase and inactivated derivatives
BU34_RS11730	COG1203	CRISPR-associated helicase, Cas3
BU34_RS11745	COG1857	crispr-associated protein
BU34_RS11760	COG1518	maintenance of DNA repeat elements
BU34_RS11765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BU34_RS11770	COG2234	aminopeptidase activity
BU34_RS11825	COG4942	peptidase
BU34_RS11825	COG1388	LysM domain
BU34_RS11830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BU34_RS11835	COG2610	gluconate transmembrane transporter activity
BU34_RS11840	COG3622	Belongs to the hyi family
BU34_RS11845	COG0235	Class ii aldolase
BU34_RS11850	COG3395	kinase activity
BU34_RS11855	COG2084	Dehydrogenase
BU34_RS11860	COG1349	DNA-binding transcription factor activity
BU34_RS11865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BU34_RS11885	COG3604	Transcriptional regulator
BU34_RS11890	COG0309	Hydrogenase expression formation protein (HypE)
BU34_RS11895	COG0409	Hydrogenase expression formation protein
BU34_RS11900	COG0298	carbon dioxide binding
BU34_RS11905	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BU34_RS11910	COG0375	protein maturation
BU34_RS11925	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS11930	COG0651	ATP synthesis coupled electron transport
BU34_RS11935	COG0650	Formate hydrogenlyase subunit 4
BU34_RS11940	COG3261	NADH dehydrogenase
BU34_RS11940	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BU34_RS11945	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BU34_RS11950	COG3260	NADH ubiquinone oxidoreductase 20
BU34_RS11960	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BU34_RS11965	COG2723	6-phospho-beta-galactosidase activity
BU34_RS11970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS11970	COG1263	PTS System
BU34_RS11975	COG1609	Transcriptional regulator
BU34_RS11980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS11985	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BU34_RS12005	COG0517	IMP dehydrogenase activity
BU34_RS12005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BU34_RS12010	COG1349	DNA-binding transcription factor activity
BU34_RS12015	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS12020	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS12025	COG3731	PTS system glucitol sorbitol-specific IIA component
BU34_RS12030	COG3732	PTS system glucitol sorbitol-specific
BU34_RS12035	COG3730	PTS system glucitol sorbitol-specific
BU34_RS12040	COG2951	lytic endotransglycosylase activity
BU34_RS12045	COG1546	Belongs to the CinA family
BU34_RS12070	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BU34_RS12100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BU34_RS12105	COG1238	metal cluster binding
BU34_RS12120	COG2814	Major facilitator Superfamily
BU34_RS12125	COG1566	PFAM secretion protein HlyD family protein
BU34_RS12130	COG1846	Transcriptional regulator
BU34_RS12140	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BU34_RS12145	COG2814	Major facilitator Superfamily
BU34_RS12150	COG2113	Glycine betaine
BU34_RS12155	COG4176	ABC-type proline glycine betaine transport system permease component
BU34_RS12160	COG4175	Glycine betaine
BU34_RS12165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BU34_RS12170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BU34_RS12180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BU34_RS12185	COG4575	ribosome binding
BU34_RS12200	COG2916	Histone family protein nucleoid-structuring protein H-NS
BU34_RS12205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BU34_RS12210	COG0640	Transcriptional regulator
BU34_RS12215	COG0401	homolog of Blt101
BU34_RS12220	COG1652	LysM domain
BU34_RS12225	COG1802	Transcriptional regulator
BU34_RS12230	COG1113	amino acid transport
BU34_RS12235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BU34_RS12240	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS12245	COG0579	oxidoreductase
BU34_RS12255	COG0366	Alpha amylase catalytic
BU34_RS12260	COG0366	Alpha amylase catalytic
BU34_RS12270	COG1662	PFAM IS1 transposase
BU34_RS12275	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BU34_RS12285	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BU34_RS12295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BU34_RS12300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BU34_RS12305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BU34_RS12310	COG1120	ATPase activity
BU34_RS12315	COG2085	NADP oxidoreductase coenzyme F420-dependent
BU34_RS12320	COG2963	transposase activity
BU34_RS12340	COG1064	alcohol dehydrogenase
BU34_RS12345	COG0433	COG0433 Predicted ATPase
BU34_RS12350	COG0795	lipopolysaccharide-transporting ATPase activity
BU34_RS12355	COG0795	lipopolysaccharide-transporting ATPase activity
BU34_RS12365	COG2927	DNA polymerase III (CHI subunit)
BU34_RS12375	COG4269	membrane
BU34_RS12380	COG0456	acetyltransferase
BU34_RS12385	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BU34_RS12400	COG2731	YhcH YjgK YiaL family protein
BU34_RS12405	COG1309	transcriptional regulator
BU34_RS12410	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS12415	COG0251	oxidation-reduction process
BU34_RS12440	COG0251	oxidation-reduction process
BU34_RS12445	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BU34_RS12450	COG1609	Transcriptional regulator
BU34_RS12455	COG1263	PTS System
BU34_RS12455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS12460	COG0366	Alpha amylase catalytic
BU34_RS12465	COG1328	CTP reductase activity
BU34_RS12470	COG0602	queuosine metabolic process
BU34_RS12475	COG3783	Cytochrome b(562)
BU34_RS12480	COG0312	modulator of DNA gyrase
BU34_RS12490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BU34_RS12500	COG1172	Belongs to the binding-protein-dependent transport system permease family
BU34_RS12505	COG1172	Belongs to the binding-protein-dependent transport system permease family
BU34_RS12510	COG1129	ABC transporter
BU34_RS12515	COG1879	ABC-type sugar transport system periplasmic component
BU34_RS12520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BU34_RS12525	COG2105	PFAM AIG2 family protein
BU34_RS12530	COG2911	Protein conserved in bacteria
BU34_RS12535	COG0729	surface antigen
BU34_RS12550	COG1253	flavin adenine dinucleotide binding
BU34_RS12560	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BU34_RS12565	COG1218	3'(2'),5'-bisphosphate nucleotidase
BU34_RS12570	COG0737	Belongs to the 5'-nucleotidase family
BU34_RS12575	COG1733	regulation of RNA biosynthetic process
BU34_RS12580	COG0702	epimerase
BU34_RS12585	COG0697	spore germination
BU34_RS12595	COG1113	amino acid transport
BU34_RS12600	COG0545	Peptidyl-prolyl cis-trans isomerase
BU34_RS12605	COG3061	Opacity-associated protein A
BU34_RS12610	COG1309	transcriptional regulator
BU34_RS12625	COG1024	Enoyl-CoA hydratase
BU34_RS12630	COG4670	ketone body catabolic process
BU34_RS12635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BU34_RS12640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BU34_RS12650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BU34_RS12660	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BU34_RS12705	COG3414	Phosphotransferase system galactitol-specific IIB component
BU34_RS12710	COG3037	sugar-specific permease SgaT UlaA
BU34_RS12725	COG1073	alpha beta
BU34_RS12730	COG3650	response to hydrogen peroxide
BU34_RS12740	COG1960	acyl-CoA dehydrogenase activity
BU34_RS12745	COG0754	glutathionylspermidine amidase activity
BU34_RS12750	COG5463	Belongs to the UPF0441 family
BU34_RS12755	COG3766	membrane
BU34_RS12765	COG1842	Phage shock protein A
BU34_RS12770	COG3789	protein conserved in bacteria
BU34_RS12775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BU34_RS12780	COG0557	exoribonuclease II activity
BU34_RS12795	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BU34_RS12800	COG0330	HflC and HflK could
BU34_RS12805	COG0330	HflC and HflK could
BU34_RS12810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BU34_RS12830	COG0860	N-Acetylmuramoyl-L-alanine amidase
BU34_RS12835	COG0802	atpase or kinase
BU34_RS12840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BU34_RS12840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BU34_RS12845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BU34_RS12880	COG3264	Mechanosensitive ion channel
BU34_RS12880	COG1511	domain protein
BU34_RS12895	COG0531	amino acid
BU34_RS12905	COG1053	succinate dehydrogenase
BU34_RS12910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BU34_RS12925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BU34_RS12930	COG3040	lipid binding
BU34_RS12935	COG2076	Multidrug Resistance protein
BU34_RS12940	COG5510	response to toxic substance
BU34_RS12945	COG5510	response to toxic substance
BU34_RS12955	COG1509	lysine 2,3-aminomutase activity
BU34_RS12980	COG0531	amino acid
BU34_RS12985	COG3030	protein affecting phage T7 exclusion by the F plasmid
BU34_RS12990	COG1027	Aspartate ammonia-lyase
BU34_RS12995	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BU34_RS13005	COG4232	protein-disulfide reductase activity
BU34_RS13010	COG1309	transcriptional regulator
BU34_RS13020	COG3710	Transcriptional regulator
BU34_RS13025	COG0531	amino acid
BU34_RS13030	COG1982	Orn Lys Arg decarboxylase major
BU34_RS13035	COG3104	oligopeptide transport
BU34_RS13040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BU34_RS13055	COG2388	GCN5-related N-acetyl-transferase
BU34_RS13060	COG3592	Divergent 4Fe-4S mono-cluster
BU34_RS13065	COG3290	protein histidine kinase activity
BU34_RS13070	COG4565	transcriptional regulatory protein
BU34_RS13080	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BU34_RS13085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BU34_RS13085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BU34_RS13090	COG3647	Membrane
BU34_RS13095	COG2211	Major facilitator Superfamily
BU34_RS13100	COG1486	melibiose metabolic process
BU34_RS13110	COG2169	Transcriptional regulator
BU34_RS13115	COG1982	Orn Lys Arg decarboxylase major
BU34_RS13120	COG2207	Transcriptional regulator
BU34_RS13125	COG1662	PFAM IS1 transposase
BU34_RS13130	COG0531	amino acid
BU34_RS13135	COG2194	sulfuric ester hydrolase activity
BU34_RS13140	COG0745	RESPONSE REGULATOR receiver
BU34_RS13145	COG0642	Histidine kinase
BU34_RS13155	COG0477	Major facilitator Superfamily
BU34_RS13170	COG2824	Alkylphosphonate utilization operon protein PhnA
BU34_RS13175	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BU34_RS13185	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BU34_RS13190	COG3639	organic phosphonate transmembrane transporter activity
BU34_RS13195	COG2188	Transcriptional regulator
BU34_RS13200	COG3624	Phosphonate C-P lyase system protein PhnG
BU34_RS13205	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BU34_RS13210	COG3626	phosphonate metabolism
BU34_RS13215	COG3627	carbon phosphorus lyase activity
BU34_RS13220	COG4107	phosphonate C-P lyase system protein PhnK
BU34_RS13225	COG4778	phosphonate C-P lyase system protein PhnL
BU34_RS13230	COG3454	Phosphonate metabolism
BU34_RS13235	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BU34_RS13240	COG0456	acetyltransferase
BU34_RS13245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BU34_RS13255	COG0698	ribose 5-phosphate isomerase
BU34_RS13260	COG1737	Transcriptional regulator
BU34_RS13265	COG1879	ABC-type sugar transport system periplasmic component
BU34_RS13270	COG1129	ABC transporter
BU34_RS13275	COG1172	Belongs to the binding-protein-dependent transport system permease family
BU34_RS13280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BU34_RS13285	COG1940	carbohydrate kinase activity
BU34_RS13290	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BU34_RS13300	COG1566	PFAM secretion protein HlyD family protein
BU34_RS13305	COG1289	transmembrane transporter activity
BU34_RS13310	COG1538	Outer membrane efflux protein
BU34_RS13315	COG3383	formate dehydrogenase (NAD+) activity
BU34_RS13320	COG3383	formate dehydrogenase (NAD+) activity
BU34_RS13325	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BU34_RS13330	COG1301	dicarboxylic acid transport
BU34_RS13335	COG4235	cytochrome complex assembly
BU34_RS13340	COG3088	subunit of a heme lyase
BU34_RS13345	COG1138	Cytochrome C-type biogenesis protein
BU34_RS13350	COG3301	Polysulphide reductase, NrfD
BU34_RS13355	COG0437	4 iron, 4 sulfur cluster binding
BU34_RS13360	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BU34_RS13370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BU34_RS13375	COG3162	membrane
BU34_RS13385	COG1357	PFAM Pentapeptide repeats (8 copies)
BU34_RS13390	COG0025	NhaP-type Na H and K H
BU34_RS13395	COG2252	PERMEase
BU34_RS13400	COG0789	Transcriptional regulator
BU34_RS13405	COG2207	Transcriptional regulator
BU34_RS13410	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BU34_RS13420	COG0629	single-stranded DNA binding
BU34_RS13425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BU34_RS13430	COG2315	Protein conserved in bacteria
BU34_RS13440	COG3700	Belongs to the class B bacterial acid phosphatase family
BU34_RS13450	COG1448	Aminotransferase
BU34_RS13455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BU34_RS13460	COG0305	Participates in initiation and elongation during chromosome replication
BU34_RS13465	COG0604	alcohol dehydrogenase
BU34_RS13475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BU34_RS13490	COG0735	belongs to the Fur family
BU34_RS13495	COG3237	CsbD-like
BU34_RS13500	COG0534	Mate efflux family protein
BU34_RS13510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BU34_RS13530	COG1357	PFAM Pentapeptide repeats (8 copies)
BU34_RS13550	COG3842	ATPase activity
BU34_RS13560	COG2182	Extracellular solute-binding protein
BU34_RS13565	COG1175	transmembrane transport
BU34_RS13570	COG3833	ABC-type maltose transport systems, permease component
BU34_RS13575	COG2814	Major facilitator Superfamily
BU34_RS13575	COG0477	Major facilitator Superfamily
BU34_RS13595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BU34_RS13620	COG0527	aspartate kinase activity
BU34_RS13630	COG1187	pseudouridine synthase activity
BU34_RS13640	COG1283	sodium-dependent phosphate transmembrane transporter activity
BU34_RS13645	COG0646	methionine synthase
BU34_RS13645	COG1410	methionine synthase
BU34_RS13650	COG1414	Transcriptional regulator
BU34_RS13665	COG2224	Isocitrate lyase
BU34_RS13670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BU34_RS13680	COG0456	acetyltransferase
BU34_RS13710	COG0151	Belongs to the GarS family
BU34_RS13715	COG2204	response regulator
BU34_RS13720	COG4191	Histidine kinase
BU34_RS13725	COG3678	ATP-independent chaperone mediated protein folding
BU34_RS13740	COG3068	Protein conserved in bacteria
BU34_RS13775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BU34_RS13780	COG2104	thiamine diphosphate biosynthetic process
BU34_RS13790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BU34_RS13830	COG0250	Participates in transcription elongation, termination and antitermination
BU34_RS13835	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BU34_RS13875	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BU34_RS13875	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BU34_RS13905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BU34_RS13910	COG4206	TonB-dependent receptor
BU34_RS13935	COG0583	DNA-binding transcription factor activity
BU34_RS13950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BU34_RS13970	COG2194	sulfuric ester hydrolase activity
BU34_RS13975	COG2207	Transcriptional regulator
BU34_RS13985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS13990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BU34_RS13995	COG1882	Formate acetyltransferase
BU34_RS14000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS14005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS14010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS14010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BU34_RS14010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS14015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BU34_RS14020	COG0371	Dehydrogenase
BU34_RS14035	COG0697	spore germination
BU34_RS14045	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BU34_RS14055	COG0527	aspartate kinase activity
BU34_RS14055	COG0460	homoserine dehydrogenase
BU34_RS14060	COG0626	cystathionine gamma-synthase activity
BU34_RS14070	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BU34_RS14095	COG3209	COG3209 Rhs family protein
BU34_RS14095	COG3209	COG3209 Rhs family protein
BU34_RS14105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BU34_RS14110	COG1609	Transcriptional regulator
BU34_RS14115	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BU34_RS14130	COG1575	Belongs to the MenA family. Type 1 subfamily
BU34_RS14145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BU34_RS14155	COG1494	fructose-1,6-bisphosphatase
BU34_RS14160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BU34_RS14165	COG0589	response to stress
BU34_RS14170	COG3691	Protein conserved in bacteria
BU34_RS14175	COG3152	Membrane
BU34_RS14195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BU34_RS14210	COG3678	ATP-independent chaperone mediated protein folding
BU34_RS14215	COG0745	RESPONSE REGULATOR receiver
BU34_RS14220	COG2205	protein histidine kinase activity
BU34_RS14225	COG2258	MOSC domain
BU34_RS14240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BU34_RS14290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS14295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS14295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS14300	COG1363	Peptidase, m42
BU34_RS14305	COG3711	transcriptional antiterminator
BU34_RS14305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS14320	COG3383	formate dehydrogenase (NAD+) activity
BU34_RS14320	COG0243	molybdopterin cofactor binding
BU34_RS14325	COG0243	molybdopterin cofactor binding
BU34_RS14325	COG3383	formate dehydrogenase (NAD+) activity
BU34_RS14330	COG0437	4 iron, 4 sulfur cluster binding
BU34_RS14335	COG2864	formate dehydrogenase
BU34_RS14350	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BU34_RS14355	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BU34_RS14360	COG0456	acetyltransferase
BU34_RS14375	COG1011	Hydrolase
BU34_RS14380	COG1349	DNA-binding transcription factor activity
BU34_RS14385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BU34_RS14390	COG2084	Dehydrogenase
BU34_RS14395	COG3684	Belongs to the aldolase LacD family
BU34_RS14400	COG2942	2-epimerase
BU34_RS14405	COG2017	converts alpha-aldose to the beta-anomer
BU34_RS14415	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BU34_RS14420	COG2271	Major facilitator Superfamily
BU34_RS14425	COG1082	Xylose isomerase domain protein TIM barrel
BU34_RS14430	COG2188	Transcriptional regulator
BU34_RS14435	COG1217	gtp-binding protein TYPA
BU34_RS14445	COG0174	glutamine synthetase
BU34_RS14450	COG3852	Histidine kinase
BU34_RS14455	COG2204	response regulator
BU34_RS14465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BU34_RS14480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BU34_RS14480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BU34_RS14490	COG0204	Acyl-transferase
BU34_RS14495	COG5339	Protein conserved in bacteria
BU34_RS14500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BU34_RS14505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BU34_RS14510	COG3084	Protein conserved in bacteria
BU34_RS14515	COG0746	molybdenum cofactor guanylyltransferase activity
BU34_RS14520	COG1763	Mo-molybdopterin cofactor biosynthetic process
BU34_RS14550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BU34_RS14575	COG1253	flavin adenine dinucleotide binding
BU34_RS14590	COG2982	Protein involved in outer membrane biogenesis
BU34_RS14600	COG0572	uridine kinase
BU34_RS14605	COG5002	protein histidine kinase activity
BU34_RS14605	COG5001	Diguanylate cyclase
BU34_RS14605	COG3447	MASE1 domain protein
BU34_RS14610	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BU34_RS14615	COG0443	Heat shock 70 kDa protein
BU34_RS14620	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
BU34_RS14630	COG4245	von Willebrand factor, type A
BU34_RS14655	COG2205	protein histidine kinase activity
BU34_RS14660	COG0745	RESPONSE REGULATOR receiver
BU34_RS14675	COG0826	peptidase U32
BU34_RS14700	COG1063	alcohol dehydrogenase
BU34_RS14705	COG1662	PFAM IS1 transposase
BU34_RS14710	COG1063	alcohol dehydrogenase
BU34_RS14715	COG3775	system Galactitol-specific IIC component
BU34_RS14725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS14740	COG1830	Aldolase
BU34_RS14745	COG2211	Major facilitator Superfamily
BU34_RS14750	COG1397	ADP-ribosylglycohydrolase
BU34_RS14755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BU34_RS14760	COG2188	Transcriptional regulator
BU34_RS14765	COG3757	hydrolase, family 25
BU34_RS14770	COG0351	phosphomethylpyrimidine kinase
BU34_RS14785	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BU34_RS14790	COG5455	response to cobalt ion
BU34_RS14795	COG3539	Fimbrial protein
BU34_RS14800	COG3188	usher protein
BU34_RS14805	COG3121	Chaperone
BU34_RS14815	COG3539	Fimbrial protein
BU34_RS14830	COG0489	protein tyrosine kinase activity
BU34_RS14840	COG3831	ATPase activity
BU34_RS14845	COG3831	ATPase activity
BU34_RS14855	COG0714	Associated with various cellular activities
BU34_RS14860	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BU34_RS14865	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BU34_RS14870	COG4715	Zinc finger, swim domain protein
BU34_RS14875	COG4808	Protein conserved in bacteria
BU34_RS14880	COG4807	Protein conserved in bacteria
BU34_RS14885	COG3279	Response regulator of the LytR AlgR family
BU34_RS14890	COG3275	phosphorelay sensor kinase activity
BU34_RS14895	COG0789	Transcriptional regulator
BU34_RS14905	COG1174	glycine betaine transport
BU34_RS14910	COG1125	glycine betaine transport
BU34_RS14915	COG1174	glycine betaine transport
BU34_RS14920	COG1732	Glycine betaine
BU34_RS14925	COG1472	Belongs to the glycosyl hydrolase 3 family
BU34_RS14930	COG0277	FAD linked oxidase domain protein
BU34_RS14935	COG1686	Belongs to the peptidase S11 family
BU34_RS14945	COG0586	Pfam SNARE associated Golgi protein
BU34_RS14950	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS14965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BU34_RS14975	COG1346	cytolysis
BU34_RS14985	COG2949	membrane
BU34_RS14995	COG0493	'glutamate synthase
BU34_RS15000	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BU34_RS15000	COG0167	dihydroorotate dehydrogenase activity
BU34_RS15005	COG4211	Belongs to the binding-protein-dependent transport system permease family
BU34_RS15010	COG1129	ABC transporter
BU34_RS15015	COG1879	ABC-type sugar transport system periplasmic component
BU34_RS15020	COG1609	Transcriptional regulator
BU34_RS15030	COG2311	Membrane
BU34_RS15050	COG4771	TonB-dependent receptor
BU34_RS15055	COG0833	amino acid
BU34_RS15060	COG0583	DNA-binding transcription factor activity
BU34_RS15065	COG2855	membrane
BU34_RS15075	COG1522	sequence-specific DNA binding
BU34_RS15075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BU34_RS15080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BU34_RS15090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BU34_RS15095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BU34_RS15100	COG2313	pseudouridylate synthase activity
BU34_RS15105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BU34_RS15110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS15110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BU34_RS15110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS15115	COG1105	Belongs to the carbohydrate kinase PfkB family
BU34_RS15120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS15120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS15125	COG2814	Major facilitator Superfamily
BU34_RS15140	COG0246	Mannitol dehydrogenase
BU34_RS15145	COG0523	cobalamin synthesis protein
BU34_RS15150	COG0671	phosphoesterase, PA-phosphatase related
BU34_RS15155	COG0791	NLP P60 protein
BU34_RS15160	COG2200	EAL domain
BU34_RS15165	COG4166	transmembrane transport
BU34_RS15170	COG4174	ABC transporter (Permease)
BU34_RS15175	COG4239	(ABC) transporter, permease
BU34_RS15180	COG4172	Belongs to the ABC transporter superfamily
BU34_RS15190	COG2814	Major facilitator Superfamily
BU34_RS15195	COG1187	pseudouridine synthase activity
BU34_RS15200	COG1061	Type III restriction enzyme res subunit
BU34_RS15220	COG3083	sulfuric ester hydrolase activity
BU34_RS15240	COG2197	response regulator
BU34_RS15245	COG3088	subunit of a heme lyase
BU34_RS15245	COG4235	cytochrome complex assembly
BU34_RS15250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BU34_RS15255	COG1138	Cytochrome C-type biogenesis protein
BU34_RS15265	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BU34_RS15270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BU34_RS15275	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BU34_RS15285	COG3005	denitrification pathway
BU34_RS15290	COG3043	anaerobic respiration
BU34_RS15295	COG0348	domain, Protein
BU34_RS15300	COG0437	4 iron, 4 sulfur cluster binding
BU34_RS15310	COG3062	negative regulation of establishment of protein localization
BU34_RS15315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS15315	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS15335	COG4615	Cyclic peptide transporter
BU34_RS15340	COG3145	DNA-N1-methyladenine dioxygenase activity
BU34_RS15345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BU34_RS15345	COG2169	Transcriptional regulator
BU34_RS15350	COG1477	protein flavinylation
BU34_RS15355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BU34_RS15370	COG0642	Histidine kinase
BU34_RS15370	COG2198	Histidine kinase
BU34_RS15375	COG2197	response regulator
BU34_RS15380	COG2205	protein histidine kinase activity
BU34_RS15380	COG0784	Response regulator, receiver
BU34_RS15385	COG4676	Protein conserved in bacteria
BU34_RS15390	COG5445	Predicted secreted protein (DUF2300)
BU34_RS15395	COG2373	Large extracellular alpha-helical protein
BU34_RS15400	COG3234	Protein of unknown function (DUF1175)
BU34_RS15405	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
BU34_RS15410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BU34_RS15420	COG3468	outer membrane autotransporter barrel domain protein
BU34_RS15430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BU34_RS15435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BU34_RS15440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BU34_RS15445	COG3642	lipopolysaccharide core region biosynthetic process
BU34_RS15450	COG0583	DNA-binding transcription factor activity
BU34_RS15455	COG0584	glycerophosphoryl diester phosphodiesterase
BU34_RS15460	COG2271	Major facilitator Superfamily
BU34_RS15465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BU34_RS15475	COG0247	lactate metabolic process
BU34_RS15480	COG5464	transposase or invertase
BU34_RS15500	COG1414	Transcriptional regulator
BU34_RS15565	COG0318	PFAM AMP-dependent synthetase and ligase
BU34_RS15575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BU34_RS15590	COG1169	isochorismate synthase
BU34_RS15595	COG4575	ribosome binding
BU34_RS15600	COG2153	protein acetylation
BU34_RS15615	COG2234	aminopeptidase activity
BU34_RS15630	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BU34_RS15635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BU34_RS15645	COG0839	Belongs to the complex I subunit 6 family
BU34_RS15665	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BU34_RS15670	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BU34_RS15690	COG0583	DNA-binding transcription factor activity
BU34_RS15695	COG0436	Aminotransferase
BU34_RS15705	COG0490	domain, Protein
BU34_RS15705	COG0471	metal ion transport
BU34_RS15710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BU34_RS15730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BU34_RS15735	COG0280	phosphate acetyltransferase
BU34_RS15735	COG0857	belongs to the CobB CobQ family
BU34_RS15740	COG1288	antiporter activity
BU34_RS15745	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BU34_RS15750	COG0622	Phosphoesterase
BU34_RS15755	COG0625	glutathione transferase activity
BU34_RS15760	COG0625	glutathione transferase activity
BU34_RS15765	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BU34_RS15770	COG1090	epimerase
BU34_RS15780	COG4598	ABC transporter
BU34_RS15785	COG4160	amino acid transport
BU34_RS15790	COG4215	(ABC) transporter
BU34_RS15795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BU34_RS15800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BU34_RS15805	COG0163	prenyltransferase activity
BU34_RS15810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BU34_RS15815	COG1286	toxin biosynthetic process
BU34_RS15820	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BU34_RS15825	COG0285	dihydrofolate synthase activity
BU34_RS15835	COG0586	Pfam SNARE associated Golgi protein
BU34_RS15845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BU34_RS15860	COG2814	Major facilitator Superfamily
BU34_RS15865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BU34_RS15880	COG3101	peptidyl-lysine hydroxylation
BU34_RS15885	COG0730	response to heat
BU34_RS15915	COG3539	Fimbrial protein
BU34_RS15920	COG3539	Fimbrial protein
BU34_RS15925	COG3539	Fimbrial protein
BU34_RS15930	COG3121	Chaperone
BU34_RS15935	COG3188	usher protein
BU34_RS15940	COG3539	Fimbrial protein
BU34_RS15945	COG2062	phosphohistidine phosphatase, SixA
BU34_RS15960	COG3691	Protein conserved in bacteria
BU34_RS15965	COG2067	long-chain fatty acid transport protein
BU34_RS15975	COG2853	Lipoprotein
BU34_RS15980	COG2116	formate transmembrane transporter activity
BU34_RS15990	COG0582	viral genome integration into host DNA
BU34_RS16145	COG3567	Phage-associated protein, HI1409 family
BU34_RS16150	COG1783	phage Terminase large subunit
BU34_RS16170	COG3772	lysozyme
BU34_RS16355	COG0583	DNA-binding transcription factor activity
BU34_RS16360	COG2610	gluconate transmembrane transporter activity
BU34_RS16370	COG0477	Major facilitator Superfamily
BU34_RS16375	COG1566	PFAM secretion protein HlyD family protein
BU34_RS16380	COG2197	response regulator
BU34_RS16385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BU34_RS16385	COG2198	Histidine kinase
BU34_RS16385	COG2205	protein histidine kinase activity
BU34_RS16385	COG0784	Response regulator, receiver
BU34_RS16390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BU34_RS16395	COG0679	Auxin Efflux Carrier
BU34_RS16400	COG0028	Belongs to the TPP enzyme family
BU34_RS16430	COG1560	Kdo2-lipid A biosynthetic process
BU34_RS16435	COG0436	Aminotransferase
BU34_RS16440	COG3275	phosphorelay sensor kinase activity
BU34_RS16445	COG3279	Response regulator of the LytR AlgR family
BU34_RS16450	COG2207	Transcriptional regulator
BU34_RS16455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS16455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS16455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BU34_RS16460	COG1363	Peptidase, m42
BU34_RS16465	COG0006	proline dipeptidase activity
BU34_RS16470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS16475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BU34_RS16505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BU34_RS16510	COG2199	diguanylate cyclase activity
BU34_RS16510	COG2200	EAL domain
BU34_RS16525	COG3415	Transposase
BU34_RS16530	COG3415	Transposase
BU34_RS16560	COG0583	DNA-binding transcription factor activity
BU34_RS16570	COG2211	Major facilitator Superfamily
BU34_RS16575	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BU34_RS16585	COG0583	DNA-binding transcription factor activity
BU34_RS16590	COG0385	Bile acid
BU34_RS16595	COG3530	Putative quorum-sensing-regulated virulence factor
BU34_RS16615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BU34_RS16620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS16625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BU34_RS16630	COG2190	(PTS) system
BU34_RS16645	COG4884	unkown
BU34_RS16645	COG3831	ATPase activity
BU34_RS16650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BU34_RS16655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BU34_RS16660	COG4208	sulfate ABC transporter
BU34_RS16665	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BU34_RS16670	COG4150	thiosulfate binding
BU34_RS16675	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS16690	COG1263	PTS System
BU34_RS16690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS16695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BU34_RS16700	COG2837	iron assimilation
BU34_RS16715	COG0456	acetyltransferase
BU34_RS16720	COG0860	N-Acetylmuramoyl-L-alanine amidase
BU34_RS16730	COG2207	Transcriptional regulator
BU34_RS16735	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BU34_RS16740	COG4816	utilization protein
BU34_RS16750	COG4303	Ethanolamine ammonia lyase large subunit
BU34_RS16755	COG4819	ethanolamine utilization protein
BU34_RS16760	COG3192	ethanolamine utilization protein
BU34_RS16765	COG1454	alcohol dehydrogenase
BU34_RS16770	COG4820	ethanolamine utilization protein (EutJ)
BU34_RS16775	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS16780	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BU34_RS16785	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BU34_RS16790	COG0280	phosphate acetyltransferase
BU34_RS16795	COG4812	Cobalamin adenosyltransferase
BU34_RS16800	COG4766	ethanolamine catabolic process
BU34_RS16805	COG4917	ethanolamine utilization protein
BU34_RS16810	COG4810	utilization protein
BU34_RS16815	COG0281	malic enzyme
BU34_RS16815	COG0280	phosphate acetyltransferase
BU34_RS16820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BU34_RS16825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BU34_RS16830	COG5342	invasion associated locus B
BU34_RS16840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS16840	COG0493	'glutamate synthase
BU34_RS16845	COG3850	Histidine kinase
BU34_RS16850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BU34_RS16860	COG1393	Belongs to the ArsC family
BU34_RS16875	COG0400	carboxylic ester hydrolase activity
BU34_RS16885	COG2321	neutral zinc metallopeptidase
BU34_RS16900	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BU34_RS16910	COG2716	regulation of RNA biosynthetic process
BU34_RS16915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BU34_RS16920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS16925	COG0651	ATP synthesis coupled electron transport
BU34_RS16930	COG0651	ATP synthesis coupled electron transport
BU34_RS16935	COG0650	Formate hydrogenlyase subunit 4
BU34_RS16940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BU34_RS16945	COG4237	Hydrogenase 4 membrane
BU34_RS16950	COG0651	ATP synthesis coupled electron transport
BU34_RS16955	COG3261	NADH dehydrogenase
BU34_RS16955	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BU34_RS16960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BU34_RS16965	COG3260	NADH ubiquinone oxidoreductase 20
BU34_RS16975	COG3604	Transcriptional regulator
BU34_RS16980	COG2116	formate transmembrane transporter activity
BU34_RS16985	COG0628	permease
BU34_RS16990	COG4783	chaperone-mediated protein folding
BU34_RS16995	COG1393	Belongs to the ArsC family
BU34_RS17005	COG2233	PERMEase
BU34_RS17020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BU34_RS17025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BU34_RS17030	COG0248	Ppx GppA phosphatase
BU34_RS17035	COG2200	EAL domain
BU34_RS17050	COG3133	Outer membrane lipoprotein
BU34_RS17065	COG0516	GMP reductase activity
BU34_RS17065	COG0517	IMP dehydrogenase activity
BU34_RS17075	COG1645	bacterial-type flagellum-dependent swarming motility
BU34_RS17090	COG2976	Protein conserved in bacteria
BU34_RS17120	COG4953	penicillin-binding protein 1C
BU34_RS17125	COG2373	Large extracellular alpha-helical protein
BU34_RS17130	COG2897	thiosulfate sulfurtransferase activity
BU34_RS17145	COG2975	iron-sulfur cluster assembly
BU34_RS17150	COG0633	Ferredoxin
BU34_RS17170	COG0822	iron-sulfur transferase activity
BU34_RS17190	COG0483	inositol monophosphate 1-phosphatase activity
BU34_RS17195	COG1073	alpha beta
BU34_RS17200	COG3711	transcriptional antiterminator
BU34_RS17205	COG2814	Major facilitator Superfamily
BU34_RS17210	COG0583	DNA-binding transcription factor activity
BU34_RS17215	COG4638	Rieske (2fe-2S)
BU34_RS17240	COG2259	Doxx family
BU34_RS17245	COG2017	converts alpha-aldose to the beta-anomer
BU34_RS17250	COG1063	alcohol dehydrogenase
BU34_RS17255	COG1172	Belongs to the binding-protein-dependent transport system permease family
BU34_RS17260	COG1129	ABC transporter
BU34_RS17265	COG1879	ABC-type sugar transport system periplasmic component
BU34_RS17270	COG0457	Tetratricopeptide repeat
BU34_RS17275	COG1940	carbohydrate kinase activity
BU34_RS17285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BU34_RS17285	COG1017	nitric oxide dioxygenase activity
BU34_RS17290	COG0347	Belongs to the P(II) protein family
BU34_RS17295	COG2204	response regulator
BU34_RS17300	COG3170	Tfp pilus assembly protein FimV
BU34_RS17305	COG2205	protein histidine kinase activity
BU34_RS17325	COG0560	Phosphoserine phosphatase
BU34_RS17330	COG1737	Transcriptional regulator
BU34_RS17335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS17360	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BU34_RS17380	COG0681	Belongs to the peptidase S26 family
BU34_RS17390	COG3086	response to oxidative stress
BU34_RS17395	COG3026	antisigma factor binding
BU34_RS17400	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BU34_RS17405	COG1595	DNA-templated transcription, initiation
BU34_RS17415	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BU34_RS17425	COG0513	Belongs to the DEAD box helicase family
BU34_RS17435	COG0583	DNA-binding transcription factor activity
BU34_RS17455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BU34_RS17465	COG3118	belongs to the thioredoxin family
BU34_RS17470	COG3148	PFAM DTW domain containing protein
BU34_RS17475	COG1042	CoA-binding domain protein
BU34_RS17475	COG0045	succinate-CoA ligase (ADP-forming) activity
BU34_RS17475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BU34_RS17480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BU34_RS17485	COG5544	Lipoprotein
BU34_RS17495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BU34_RS17545	COG0438	transferase activity, transferring glycosyl groups
BU34_RS17555	COG0140	phosphoribosyl-ATP diphosphatase activity
BU34_RS17555	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BU34_RS17570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BU34_RS17575	COG0131	Imidazoleglycerol-phosphate dehydratase
BU34_RS17575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BU34_RS17595	COG2161	toxin-antitoxin pair type II binding
BU34_RS17600	COG4115	mRNA cleavage
BU34_RS17605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BU34_RS17610	COG0583	DNA-binding transcription factor activity
BU34_RS17615	COG0531	amino acid
BU34_RS17620	COG2391	methyltransferase activity
BU34_RS17625	COG0425	Belongs to the sulfur carrier protein TusA family
BU34_RS17630	COG2925	Exonuclease
BU34_RS17635	COG1686	Belongs to the peptidase S11 family
BU34_RS17645	COG1289	transmembrane transporter activity
BU34_RS17655	COG4917	ethanolamine utilization protein
BU34_RS17690	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BU34_RS17705	COG1376	ErfK ybiS ycfS ynhG family protein
BU34_RS17715	COG0583	DNA-binding transcription factor activity
BU34_RS17720	COG0583	DNA-binding transcription factor activity
BU34_RS17730	COG0534	Mate efflux family protein
BU34_RS17735	COG0534	Mate efflux family protein
BU34_RS17750	COG0217	transcriptional regulatory protein
BU34_RS17755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BU34_RS17760	COG0477	Major facilitator Superfamily
BU34_RS17770	COG4932	domain protein
BU34_RS17770	COG2373	Large extracellular alpha-helical protein
BU34_RS17770	COG1388	LysM domain
BU34_RS17795	COG3038	cytochrome b561
BU34_RS17800	COG3443	Belongs to the bacterial solute-binding protein 9 family
BU34_RS17815	COG2351	hydroxyisourate hydrolase activity
BU34_RS17820	COG0745	RESPONSE REGULATOR receiver
BU34_RS17825	COG2205	protein histidine kinase activity
BU34_RS17840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BU34_RS17855	COG1418	mRNA catabolic process
BU34_RS17860	COG0270	DNA (cytosine-5-)-methyltransferase activity
BU34_RS17865	COG3727	T/G mismatch-specific endonuclease activity
BU34_RS17870	COG0697	spore germination
BU34_RS17875	COG2354	Protein conserved in bacteria
BU34_RS17880	COG5475	Uncharacterized small protein (DUF2158)
BU34_RS17910	COG1662	PFAM IS1 transposase
BU34_RS17925	COG2076	Multidrug Resistance protein
BU34_RS17930	COG1881	PFAM PEBP family protein
BU34_RS17935	COG2207	Transcriptional regulator
BU34_RS17955	COG0675	Transposase, IS605 OrfB family
BU34_RS17960	COG2135	peptidase activity
BU34_RS17965	COG0425	Belongs to the sulfur carrier protein TusA family
BU34_RS17970	COG2391	methyltransferase activity
BU34_RS17980	COG0366	Alpha amylase catalytic
BU34_RS17990	COG1516	flagellar protein fliS
BU34_RS17995	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BU34_RS18005	COG1191	sigma factor activity
BU34_RS18015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BU34_RS18025	COG0765	amino acid transport
BU34_RS18030	COG1126	abc transporter atp-binding protein
BU34_RS18035	COG2197	response regulator
BU34_RS18050	COG2197	response regulator
BU34_RS18080	COG3318	Belongs to the UPF0149 family
BU34_RS18080	COG3012	SEC-C Motif Domain Protein
BU34_RS18085	COG0814	amino acid
BU34_RS18095	COG1528	Iron-storage protein
BU34_RS18115	COG1528	Iron-storage protein
BU34_RS18120	COG1879	ABC-type sugar transport system periplasmic component
BU34_RS18125	COG1129	ABC transporter
BU34_RS18130	COG1172	Belongs to the binding-protein-dependent transport system permease family
BU34_RS18135	COG1877	trehalose-phosphatase activity
BU34_RS18145	COG0589	response to stress
BU34_RS18160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BU34_RS18165	COG1360	Flagellar Motor Protein
BU34_RS18170	COG2198	Histidine kinase
BU34_RS18170	COG0643	Histidine kinase
BU34_RS18180	COG0840	transmembrane signaling receptor activity
BU34_RS18190	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BU34_RS18200	COG0745	RESPONSE REGULATOR receiver
BU34_RS18205	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BU34_RS18215	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BU34_RS18225	COG3755	Protein conserved in bacteria
BU34_RS18235	COG3102	Protein conserved in bacteria
BU34_RS18245	COG3005	denitrification pathway
BU34_RS18250	COG0243	molybdopterin cofactor binding
BU34_RS18265	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BU34_RS18270	COG1801	Protein of unknown function DUF72
BU34_RS18350	COG1335	isochorismatase
BU34_RS18360	COG0494	nUDIX hydrolase
BU34_RS18365	COG0217	transcriptional regulatory protein
BU34_RS18390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BU34_RS18400	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BU34_RS18405	COG0739	heme binding
BU34_RS18410	COG1560	Kdo2-lipid A biosynthetic process
BU34_RS18415	COG0469	pyruvate kinase activity
BU34_RS18420	COG1737	Transcriptional regulator
BU34_RS18430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BU34_RS18435	COG0129	dihydroxy-acid dehydratase activity
BU34_RS18440	COG0800	Aldolase
BU34_RS18450	COG3141	response to X-ray
BU34_RS18465	COG2979	Protein of unknown function (DUF533)
BU34_RS18470	COG1770	oligopeptidase
BU34_RS18475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BU34_RS18480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BU34_RS18490	COG2372	response to copper ion
BU34_RS18495	COG1276	copper resistance
BU34_RS18510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BU34_RS18530	COG3008	intermembrane lipid transfer
BU34_RS18535	COG2995	paraquat-inducible protein a
BU34_RS18540	COG1956	GAF domain-containing protein
BU34_RS18550	COG0793	Belongs to the peptidase S41A family
BU34_RS18560	COG2814	Major facilitator Superfamily
BU34_RS18565	COG1414	Transcriptional regulator
BU34_RS18600	COG2226	methyltransferase
BU34_RS18620	COG3716	PTS system mannose fructose sorbose family IID component
BU34_RS18625	COG3715	PTS system
BU34_RS18630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS18630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS18640	COG1253	flavin adenine dinucleotide binding
BU34_RS18645	COG2200	EAL domain
BU34_RS18650	COG1760	l-serine dehydratase
BU34_RS18660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BU34_RS18680	COG0251	oxidation-reduction process
BU34_RS18685	COG1199	ATP-dependent helicase activity
BU34_RS18690	COG1214	PFAM Peptidase M22, glycoprotease
BU34_RS18695	COG3065	identical protein binding
BU34_RS18700	COG0318	PFAM AMP-dependent synthetase and ligase
BU34_RS18705	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BU34_RS18710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BU34_RS18715	COG4638	Rieske (2fe-2S)
BU34_RS18720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BU34_RS18725	COG0473	3-isopropylmalate dehydrogenase activity
BU34_RS18730	COG0583	DNA-binding transcription factor activity
BU34_RS18740	COG3615	Tellurite resistance protein tehB
BU34_RS18750	COG2261	transglycosylase associated protein
BU34_RS18760	COG2199	diguanylate cyclase activity
BU34_RS18760	COG2203	Gaf domain
BU34_RS18765	COG3042	response to heat
BU34_RS18770	COG3189	MarR family transcriptional regulator
BU34_RS18775	COG2807	transmembrane transport
BU34_RS18780	COG2207	Transcriptional regulator
BU34_RS18795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BU34_RS18800	COG2199	diguanylate cyclase activity
BU34_RS18805	COG2199	diguanylate cyclase activity
BU34_RS18815	COG2766	serine protein kinase
BU34_RS18820	COG3713	MltA-interacting MipA family protein
BU34_RS18825	COG0656	L-ascorbic acid biosynthetic process
BU34_RS18830	COG0676	glucose-6-phosphate 1-epimerase activity
BU34_RS18835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BU34_RS18845	COG3139	Protein of unknown function (DUF1315)
BU34_RS18850	COG1063	alcohol dehydrogenase
BU34_RS18855	COG2271	Major facilitator Superfamily
BU34_RS18860	COG1662	PFAM IS1 transposase
BU34_RS18865	COG0667	Aldo Keto reductase
BU34_RS18870	COG1349	DNA-binding transcription factor activity
BU34_RS18875	COG2814	Major facilitator Superfamily
BU34_RS18880	COG1335	isochorismatase
BU34_RS18885	COG0252	asparaginase activity
BU34_RS18890	COG0616	signal peptide processing
BU34_RS18900	COG0778	Nitroreductase
BU34_RS18915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BU34_RS18920	COG0443	Heat shock 70 kDa protein
BU34_RS18925	COG0484	heat shock protein binding
BU34_RS18930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BU34_RS18940	COG0494	nUDIX hydrolase
BU34_RS18945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BU34_RS18950	COG2897	thiosulfate sulfurtransferase activity
BU34_RS18955	COG4136	ATPase activity
BU34_RS18960	COG4135	transport system, permease component
BU34_RS18965	COG4134	Bacterial extracellular solute-binding protein
BU34_RS18970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BU34_RS18975	COG0398	Pfam SNARE associated Golgi protein
BU34_RS18985	COG0398	Pfam SNARE associated Golgi protein
BU34_RS18990	COG0708	Exodeoxyribonuclease III
BU34_RS19020	COG3678	ATP-independent chaperone mediated protein folding
BU34_RS19030	COG0322	excinuclease ABC activity
BU34_RS19045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BU34_RS19050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BU34_RS19055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BU34_RS19060	COG1447	Phosphotransferase system cellobiose-specific component IIA
BU34_RS19065	COG1917	Cupin 2, conserved barrel domain protein
BU34_RS19065	COG2169	Transcriptional regulator
BU34_RS19070	COG1486	melibiose metabolic process
BU34_RS19080	COG0753	catalase activity
BU34_RS19105	COG1823	symporter activity
BU34_RS19110	COG1988	membrane-bound metal-dependent
BU34_RS19115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BU34_RS19125	COG3001	Fructosamine kinase
BU34_RS19135	COG1105	Belongs to the carbohydrate kinase PfkB family
BU34_RS19140	COG3137	Salt-induced outer membrane protein
BU34_RS19155	COG1662	PFAM IS1 transposase
BU34_RS19210	COG0386	Belongs to the glutathione peroxidase family
BU34_RS19220	COG0791	NLP P60 protein
BU34_RS19225	COG2200	EAL domain
BU34_RS19235	COG4256	Hemin uptake protein
BU34_RS19240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BU34_RS19255	COG0574	Belongs to the PEP-utilizing enzyme family
BU34_RS19255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BU34_RS19260	COG0318	PFAM AMP-dependent synthetase and ligase
BU34_RS19265	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BU34_RS19270	COG0644	oxidoreductase
BU34_RS19275	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BU34_RS19280	COG2086	electron transfer activity
BU34_RS19290	COG2207	Transcriptional regulator
BU34_RS19290	COG1917	Cupin 2, conserved barrel domain protein
BU34_RS19295	COG1960	acyl-CoA dehydrogenase activity
BU34_RS19300	COG4670	ketone body catabolic process
BU34_RS19315	COG2271	Major facilitator Superfamily
BU34_RS19320	COG0738	Major facilitator superfamily
BU34_RS19330	COG0628	permease
BU34_RS19335	COG0247	lactate metabolic process
BU34_RS19335	COG0277	FAD linked oxidase domain protein
BU34_RS19340	COG2050	protein possibly involved in aromatic compounds catabolism
BU34_RS19350	COG0316	Belongs to the HesB IscA family
BU34_RS19355	COG0719	Fe-S assembly protein
BU34_RS19360	COG0396	ATPase activity
BU34_RS19365	COG0719	Fe-S assembly protein
BU34_RS19380	COG1376	ErfK ybiS ycfS ynhG family protein
BU34_RS19385	COG4238	major outer membrane lipoprotein
BU34_RS19390	COG0469	pyruvate kinase activity
BU34_RS19400	COG0437	4 iron, 4 sulfur cluster binding
BU34_RS19405	COG2414	aldehyde ferredoxin oxidoreductase
BU34_RS19415	COG0437	4 iron, 4 sulfur cluster binding
BU34_RS19420	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BU34_RS19430	COG4529	Protein conserved in bacteria
BU34_RS19450	COG3468	outer membrane autotransporter barrel domain protein
BU34_RS19460	COG0307	riboflavin synthase, alpha
BU34_RS19465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BU34_RS19470	COG2814	Major facilitator Superfamily
BU34_RS19475	COG0583	DNA-binding transcription factor activity
BU34_RS19490	COG2814	Major facilitator Superfamily
BU34_RS19495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BU34_RS19500	COG0791	NLP P60 protein
BU34_RS19505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BU34_RS19510	COG1201	RNA secondary structure unwinding
BU34_RS19520	COG0346	lactoylglutathione lyase activity
BU34_RS19525	COG1902	pentaerythritol trinitrate reductase activity
BU34_RS19530	COG1309	transcriptional regulator
BU34_RS19535	COG3313	Fe-S protein
BU34_RS19540	COG4989	oxidoreductase activity
BU34_RS19545	COG2032	superoxide dismutase activity
BU34_RS19550	COG1289	transmembrane transporter activity
BU34_RS19555	COG1566	PFAM secretion protein HlyD family protein
BU34_RS19570	COG3133	Outer membrane lipoprotein
BU34_RS19580	COG3895	Periplasmic Protein
BU34_RS19595	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BU34_RS19600	COG0625	glutathione transferase activity
BU34_RS19605	COG3104	oligopeptide transport
BU34_RS19615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BU34_RS19625	COG4659	FMN binding
BU34_RS19665	COG0673	inositol 2-dehydrogenase activity
BU34_RS19675	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BU34_RS19680	COG1263	PTS System
BU34_RS19680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS19685	COG1609	Transcriptional regulator
BU34_RS19690	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS19695	COG1309	transcriptional regulator
BU34_RS19700	COG3250	beta-galactosidase activity
BU34_RS19725	COG5339	Protein conserved in bacteria
BU34_RS19730	COG1482	cell wall glycoprotein biosynthetic process
BU34_RS19735	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BU34_RS19735	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BU34_RS19740	COG0114	fumarate hydratase activity
BU34_RS19750	COG2205	protein histidine kinase activity
BU34_RS19755	COG0745	RESPONSE REGULATOR receiver
BU34_RS19760	COG3136	membrane protein required for alginate biosynthesis
BU34_RS19770	COG0531	amino acid
BU34_RS19780	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BU34_RS19785	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BU34_RS19790	COG0628	permease
BU34_RS19805	COG3591	Belongs to the peptidase S1B family
BU34_RS19820	COG2814	Major facilitator Superfamily
BU34_RS19825	COG0583	DNA-binding transcription factor activity
BU34_RS19830	COG1940	carbohydrate kinase activity
BU34_RS19835	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BU34_RS19845	COG3381	protein complex oligomerization
BU34_RS19850	COG3302	dmso reductase anchor subunit
BU34_RS19855	COG0437	4 iron, 4 sulfur cluster binding
BU34_RS19860	COG0243	molybdopterin cofactor binding
BU34_RS19865	COG0243	molybdopterin cofactor binding
BU34_RS19880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BU34_RS19895	COG4948	Mandelate Racemase Muconate Lactonizing
BU34_RS19900	COG1063	alcohol dehydrogenase
BU34_RS19905	COG0582	viral genome integration into host DNA
BU34_RS19915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BU34_RS19930	COG1403	HNH endonuclease
BU34_RS19935	COG0484	heat shock protein binding
BU34_RS19940	COG1278	Cold shock
BU34_RS19945	COG1278	Cold shock
BU34_RS19960	COG3772	lysozyme
BU34_RS19970	COG1278	Cold shock
BU34_RS20005	COG4220	transposase activity
BU34_RS20015	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BU34_RS20020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BU34_RS20030	COG0477	Major facilitator Superfamily
BU34_RS20035	COG0246	Mannitol dehydrogenase
BU34_RS20045	COG1802	Transcriptional regulator
BU34_RS20050	COG4221	oxidoreductase activity
BU34_RS20055	COG0339	signal peptide processing
BU34_RS20060	COG1546	Belongs to the CinA family
BU34_RS20065	COG3111	PFAM Bacterial OB fold (BOF) protein
BU34_RS20070	COG3706	GGDEF domain
BU34_RS20080	COG2814	Major facilitator Superfamily
BU34_RS20085	COG0697	spore germination
BU34_RS20095	COG4977	sequence-specific DNA binding
BU34_RS20100	COG1846	Transcriptional regulator
BU34_RS20120	COG0583	DNA-binding transcription factor activity
BU34_RS20125	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS20130	COG2066	Belongs to the glutaminase family
BU34_RS20140	COG2199	diguanylate cyclase activity
BU34_RS20150	COG3781	membrane
BU34_RS20200	COG0840	transmembrane signaling receptor activity
BU34_RS20230	COG0697	spore germination
BU34_RS20255	COG1396	sequence-specific DNA binding
BU34_RS20260	COG3550	peptidyl-serine autophosphorylation
BU34_RS20265	COG4977	sequence-specific DNA binding
BU34_RS20270	COG3188	usher protein
BU34_RS20275	COG3539	Fimbrial protein
BU34_RS20280	COG3539	Fimbrial protein
BU34_RS20285	COG3539	Fimbrial protein
BU34_RS20290	COG0243	molybdopterin cofactor binding
BU34_RS20305	COG3119	arylsulfatase activity
BU34_RS20310	COG0641	radical SAM
BU34_RS20315	COG4178	(ABC) transporter
BU34_RS20320	COG4771	TonB-dependent receptor
BU34_RS20325	COG0612	Peptidase, M16
BU34_RS20335	COG0076	glutamate decarboxylase activity
BU34_RS20340	COG0531	amino acid
BU34_RS20345	COG1649	PFAM Uncharacterised BCR, COG1649
BU34_RS20350	COG3706	GGDEF domain
BU34_RS20355	COG2199	diguanylate cyclase activity
BU34_RS20355	COG2200	EAL domain
BU34_RS20355	COG2202	Pas domain
BU34_RS20360	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BU34_RS20365	COG0747	negative chemotaxis
BU34_RS20370	COG0601	transmembrane transport
BU34_RS20375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BU34_RS20380	COG0444	Belongs to the ABC transporter superfamily
BU34_RS20385	COG4608	Belongs to the ABC transporter superfamily
BU34_RS20390	COG1764	response to oxidative stress
BU34_RS20410	COG1064	alcohol dehydrogenase
BU34_RS20415	COG3093	addiction module antidote protein HigA
BU34_RS20420	COG2864	formate dehydrogenase
BU34_RS20425	COG0437	4 iron, 4 sulfur cluster binding
BU34_RS20430	COG3383	formate dehydrogenase (NAD+) activity
BU34_RS20430	COG0243	molybdopterin cofactor binding
BU34_RS20435	COG3383	formate dehydrogenase (NAD+) activity
BU34_RS20435	COG0243	molybdopterin cofactor binding
BU34_RS20440	COG0697	spore germination
BU34_RS20445	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BU34_RS20455	COG2223	nitrite transmembrane transporter activity
BU34_RS20460	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BU34_RS20465	COG1140	nitrate reductase beta subunit
BU34_RS20470	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BU34_RS20475	COG2181	nitrate reductase activity
BU34_RS20480	COG0384	phenazine biosynthesis protein PhzF
BU34_RS20485	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BU34_RS20490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BU34_RS20505	COG5433	transposase activity
BU34_RS20535	COG0625	glutathione transferase activity
BU34_RS20540	COG1113	amino acid transport
BU34_RS20545	COG3391	amine dehydrogenase activity
BU34_RS20550	COG4772	TonB-dependent receptor
BU34_RS20555	COG1802	Transcriptional regulator
BU34_RS20560	COG2130	NADP-dependent
BU34_RS20565	COG1247	-acetyltransferase
BU34_RS20570	COG3238	Protein conserved in bacteria
BU34_RS20595	COG1177	transmembrane transport
BU34_RS20600	COG1176	ABC-type spermidine putrescine transport system, permease component I
BU34_RS20605	COG3842	ATPase activity
BU34_RS20610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BU34_RS20615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BU34_RS20620	COG1598	PFAM Uncharacterised protein family UPF0150
BU34_RS20640	COG1396	sequence-specific DNA binding
BU34_RS20645	COG3135	benzoate transporter
BU34_RS20650	COG0675	Transposase, IS605 OrfB family
BU34_RS20670	COG0500	methyltransferase
BU34_RS20675	COG1275	C4-dicarboxylate transporter malic acid transport protein
BU34_RS20680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BU34_RS20685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BU34_RS20690	COG2841	Protein conserved in bacteria
BU34_RS20705	COG5383	Protein conserved in bacteria
BU34_RS20710	COG0583	DNA-binding transcription factor activity
BU34_RS20715	COG0840	transmembrane signaling receptor activity
BU34_RS20720	COG2963	transposase activity
BU34_RS20725	COG2801	Transposase and inactivated derivatives
BU34_RS20740	COG3038	cytochrome b561
BU34_RS20745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BU34_RS20750	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS20755	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BU34_RS20760	COG1643	Atp-dependent helicase
BU34_RS20770	COG2453	phosphatase
BU34_RS20770	COG0671	phosphoesterase, PA-phosphatase related
BU34_RS20775	COG2267	carboxylic ester hydrolase activity
BU34_RS20780	COG4589	Belongs to the CDS family
BU34_RS20785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BU34_RS20805	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BU34_RS20810	COG3327	negative regulation of DNA-templated transcription, initiation
BU34_RS20815	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BU34_RS20820	COG0183	Belongs to the thiolase family
BU34_RS20825	COG2050	protein possibly involved in aromatic compounds catabolism
BU34_RS20830	COG1250	3-hydroxyacyl-CoA dehydrogenase
BU34_RS20835	COG1024	Enoyl-CoA hydratase
BU34_RS20840	COG1024	Enoyl-CoA hydratase
BU34_RS20845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BU34_RS20850	COG2151	metal-sulfur cluster biosynthetic enzyme
BU34_RS20855	COG3396	Phenylacetate-CoA oxygenase
BU34_RS20860	COG3460	Phenylacetate-CoA oxygenase
BU34_RS20865	COG3396	Phenylacetate-CoA oxygenase
BU34_RS20870	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS20870	COG2030	dehydratase
BU34_RS20875	COG3733	amine oxidase
BU34_RS20880	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS20885	COG2207	Transcriptional regulator
BU34_RS20890	COG3784	Protein of unknown function (DUF1318)
BU34_RS20900	COG2911	Protein conserved in bacteria
BU34_RS20905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BU34_RS20910	COG3187	Heat shock protein
BU34_RS20915	COG3042	response to heat
BU34_RS20920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BU34_RS20920	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BU34_RS20920	COG1013	pyruvate-flavodoxin oxidoreductase activity
BU34_RS20920	COG0674	pyruvate-flavodoxin oxidoreductase activity
BU34_RS20925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BU34_RS20930	COG0589	response to stress
BU34_RS20940	COG0513	Belongs to the DEAD box helicase family
BU34_RS20955	COG3706	GGDEF domain
BU34_RS20960	COG2840	Smr protein MutS2
BU34_RS20970	COG0583	DNA-binding transcription factor activity
BU34_RS20975	COG1473	amidohydrolase
BU34_RS20980	COG1473	amidohydrolase
BU34_RS20990	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BU34_RS20995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BU34_RS21000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BU34_RS21005	COG0589	response to stress
BU34_RS21010	COG3182	Iron-regulated membrane protein
BU34_RS21015	COG0668	transmembrane transport
BU34_RS21020	COG4166	transmembrane transport
BU34_RS21030	COG0583	DNA-binding transcription factor activity
BU34_RS21035	COG1073	alpha beta
BU34_RS21040	COG0702	epimerase
BU34_RS21045	COG2866	Carboxypeptidase
BU34_RS21050	COG4948	Mandelate Racemase Muconate Lactonizing
BU34_RS21055	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BU34_RS21060	COG3283	Transcriptional regulator of aromatic amino acids metabolism
BU34_RS21070	COG3106	COG3106 Predicted ATPase
BU34_RS21075	COG1609	Transcriptional regulator
BU34_RS21085	COG3842	ATPase activity
BU34_RS21090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BU34_RS21095	COG1554	hydrolase, family 65, central catalytic
BU34_RS21100	COG0673	inositol 2-dehydrogenase activity
BU34_RS21110	COG1063	alcohol dehydrogenase
BU34_RS21115	COG0395	ABC-type sugar transport system, permease component
BU34_RS21120	COG1175	transmembrane transport
BU34_RS21125	COG1653	transport
BU34_RS21130	COG0366	Alpha amylase catalytic
BU34_RS21140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BU34_RS21150	COG1983	PspC domain protein
BU34_RS21160	COG1842	Phage shock protein A
BU34_RS21165	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BU34_RS21170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BU34_RS21175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BU34_RS21180	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS21185	COG1917	Cupin 2, conserved barrel domain protein
BU34_RS21185	COG1396	sequence-specific DNA binding
BU34_RS21190	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BU34_RS21195	COG0174	glutamine synthetase
BU34_RS21200	COG0531	amino acid
BU34_RS21215	COG4166	transmembrane transport
BU34_RS21220	COG4168	peptide transport system, permease
BU34_RS21225	COG4171	peptide transport system, permease
BU34_RS21230	COG4172	Belongs to the ABC transporter superfamily
BU34_RS21235	COG4172	Belongs to the ABC transporter superfamily
BU34_RS21240	COG2852	Protein conserved in bacteria
BU34_RS21250	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BU34_RS21255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BU34_RS21255	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BU34_RS21270	COG5001	Diguanylate cyclase
BU34_RS21280	COG1349	DNA-binding transcription factor activity
BU34_RS21290	COG0023	Translation Initiation Factor
BU34_RS21300	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BU34_RS21305	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BU34_RS21310	COG0671	phosphoesterase, PA-phosphatase related
BU34_RS21320	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BU34_RS21335	COG0598	Magnesium transport protein CorA
BU34_RS21345	COG3698	Phosphodiester glycosidase
BU34_RS21350	COG1662	PFAM IS1 transposase
BU34_RS21365	COG0583	DNA-binding transcription factor activity
BU34_RS21370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BU34_RS21385	COG0616	signal peptide processing
BU34_RS21395	COG1028	Short-chain dehydrogenase reductase Sdr
BU34_RS21400	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BU34_RS21405	COG1187	pseudouridine synthase activity
BU34_RS21415	COG0009	L-threonylcarbamoyladenylate synthase
BU34_RS21420	COG0613	PHP domain protein
BU34_RS21425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BU34_RS21430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BU34_RS21430	COG0512	Glutamine amidotransferase of anthranilate synthase
BU34_RS21435	COG0135	phosphoribosylanthranilate isomerase activity
BU34_RS21435	COG0134	indole-3-glycerol-phosphate synthase activity
BU34_RS21450	COG3729	General stress protein
BU34_RS21455	COG3685	Protein conserved in bacteria
BU34_RS21460	COG3685	Protein conserved in bacteria
BU34_RS21465	COG3047	cAMP biosynthetic process
BU34_RS21480	COG1607	acyl-coa hydrolase
BU34_RS21485	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BU34_RS21490	COG2350	Protein conserved in bacteria
BU34_RS21495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BU34_RS21515	COG4608	Belongs to the ABC transporter superfamily
BU34_RS21520	COG0444	Belongs to the ABC transporter superfamily
BU34_RS21525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BU34_RS21530	COG0601	transmembrane transport
BU34_RS21535	COG4166	transmembrane transport
BU34_RS21540	COG2095	MarC family integral membrane protein
BU34_RS21545	COG1454	alcohol dehydrogenase
BU34_RS21545	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS21550	COG1435	thymidine kinase activity
BU34_RS21560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BU34_RS21565	COG0745	RESPONSE REGULATOR receiver
BU34_RS21570	COG1752	Esterase of the alpha-beta hydrolase superfamily
BU34_RS21580	COG0788	formyltetrahydrofolate deformylase activity
BU34_RS21600	COG2181	nitrate reductase activity
BU34_RS21605	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BU34_RS21610	COG1140	nitrate reductase beta subunit
BU34_RS21615	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BU34_RS21620	COG2223	nitrite transmembrane transporter activity
BU34_RS21630	COG3850	Histidine kinase
BU34_RS21635	COG2197	response regulator
BU34_RS21640	COG4932	domain protein
BU34_RS21645	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BU34_RS21650	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BU34_RS21655	COG4572	Cation transport regulator
BU34_RS21660	COG0387	Pfam Sodium calcium exchanger
BU34_RS21675	COG2963	transposase activity
BU34_RS21680	COG2801	Transposase and inactivated derivatives
BU34_RS21695	COG2912	Transglutaminase-like superfamily
BU34_RS21700	COG3094	Invasion gene expression up-regulator, SirB
BU34_RS21705	COG2890	protein-(glutamine-N5) methyltransferase activity
BU34_RS21730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BU34_RS21735	COG0659	secondary active sulfate transmembrane transporter activity
BU34_RS21750	COG0012	GTP binding
BU34_RS21760	COG3468	outer membrane autotransporter barrel domain protein
BU34_RS21765	COG3284	Transcriptional regulator
BU34_RS21770	COG2376	Dihydroxyacetone kinase
BU34_RS21775	COG1461	Dihydroxyacetone kinase
BU34_RS21780	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BU34_RS21780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS21780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BU34_RS21800	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BU34_RS21810	COG1619	proteins homologs of microcin C7 resistance protein MccF
BU34_RS21820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BU34_RS21830	COG2719	SpoVR family
BU34_RS21845	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BU34_RS21850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BU34_RS21855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BU34_RS21870	COG0179	Fumarylacetoacetate (FAA) hydrolase
BU34_RS21900	COG2894	cell division
BU34_RS21955	COG2200	EAL domain
BU34_RS21985	COG2801	Transposase and inactivated derivatives
BU34_RS22000	COG2081	HI0933 family
BU34_RS22005	COG0306	phosphate transporter
BU34_RS22015	COG0589	response to stress
BU34_RS22020	COG3104	oligopeptide transport
BU34_RS22030	COG0339	signal peptide processing
BU34_RS22035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BU34_RS22040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BU34_RS22055	COG0640	Transcriptional regulator
BU34_RS22060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BU34_RS22065	COG1393	Belongs to the ArsC family
BU34_RS22075	COG3065	identical protein binding
BU34_RS22080	COG2197	response regulator
BU34_RS22085	COG1285	pathogenesis
BU34_RS22100	COG3247	response to pH
BU34_RS22105	COG2771	luxR family
BU34_RS22115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BU34_RS22120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BU34_RS22125	COG2207	Transcriptional regulator
BU34_RS22140	COG0076	glutamate decarboxylase activity
BU34_RS22145	COG1858	cytochrome C peroxidase
BU34_RS22155	COG1858	cytochrome C peroxidase
BU34_RS22165	COG2197	response regulator
BU34_RS22170	COG0583	DNA-binding transcription factor activity
BU34_RS22175	COG1295	ribonuclease BN
BU34_RS22180	COG0477	Major facilitator Superfamily
BU34_RS22185	COG2982	Protein involved in outer membrane biogenesis
BU34_RS22190	COG2200	EAL domain
BU34_RS22200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BU34_RS22205	COG0612	Peptidase, M16
BU34_RS22215	COG2200	EAL domain
BU34_RS22215	COG2199	diguanylate cyclase activity
BU34_RS22220	COG3118	belongs to the thioredoxin family
BU34_RS22220	COG0457	Tetratricopeptide repeat
BU34_RS22225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BU34_RS22230	COG1215	transferase activity, transferring glycosyl groups
BU34_RS22235	COG1215	transferase activity, transferring glycosyl groups
BU34_RS22270	COG2194	sulfuric ester hydrolase activity
BU34_RS22285	COG0814	amino acid
BU34_RS22290	COG4608	Belongs to the ABC transporter superfamily
BU34_RS22295	COG0444	Belongs to the ABC transporter superfamily
BU34_RS22300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BU34_RS22305	COG0601	transmembrane transport
BU34_RS22315	COG0747	negative chemotaxis
BU34_RS22330	COG2194	sulfuric ester hydrolase activity
BU34_RS22335	COG2223	nitrite transmembrane transporter activity
BU34_RS22340	COG5571	outer membrane autotransporter
BU34_RS22345	COG2818	Glycosylase
BU34_RS22350	COG0456	acetyltransferase
BU34_RS22355	COG0243	molybdopterin cofactor binding
BU34_RS22360	COG2885	chlorophyll binding
BU34_RS22375	COG2944	sequence-specific DNA binding
BU34_RS22380	COG1278	Cold shock
BU34_RS22390	COG2801	Transposase and inactivated derivatives
BU34_RS22395	COG2963	transposase activity
BU34_RS22415	COG3274	enterobacterial common antigen metabolic process
BU34_RS22420	COG4682	membrane
BU34_RS22425	COG4682	membrane
BU34_RS22430	COG1070	Carbohydrate kinase
BU34_RS22440	COG4213	ABC transporter substrate-binding protein
BU34_RS22445	COG1129	ABC transporter
BU34_RS22450	COG4214	carbohydrate transport
BU34_RS22455	COG2207	Transcriptional regulator
BU34_RS22455	COG1609	Transcriptional regulator
BU34_RS22460	COG2992	FlgJ-related protein
BU34_RS22465	COG0366	Alpha amylase catalytic
BU34_RS22470	COG3977	Valine--pyruvate aminotransferase
BU34_RS22480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BU34_RS22485	COG1414	Transcriptional regulator
BU34_RS22495	COG2731	YhcH YjgK YiaL family protein
BU34_RS22500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BU34_RS22505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BU34_RS22510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BU34_RS22515	COG1070	Carbohydrate kinase
BU34_RS22520	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BU34_RS22525	COG3623	hexulose-6-phosphate isomerase
BU34_RS22530	COG0235	Class ii aldolase
BU34_RS22540	COG2211	Major facilitator Superfamily
BU34_RS22550	COG3713	MltA-interacting MipA family protein
BU34_RS22555	COG0583	DNA-binding transcription factor activity
BU34_RS22560	COG1566	PFAM secretion protein HlyD family protein
BU34_RS22575	COG1012	belongs to the aldehyde dehydrogenase family
BU34_RS22580	COG1454	alcohol dehydrogenase
BU34_RS22585	COG3276	selenocysteine insertion sequence binding
BU34_RS22595	COG0625	glutathione transferase activity
BU34_RS22600	COG3209	COG3209 Rhs family protein
BU34_RS22605	COG1413	lyase activity
BU34_RS22610	COG3209	COG3209 Rhs family protein
BU34_RS22615	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BU34_RS22625	COG1566	PFAM secretion protein HlyD family protein
BU34_RS22635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BU34_RS22635	COG2213	PTS system mannitol-specific
BU34_RS22645	COG3722	fumarate hydratase activity
BU34_RS22665	COG5295	Hep Hag repeat protein
BU34_RS22670	COG1620	l-lactate permease
BU34_RS22675	COG2186	Transcriptional regulator
BU34_RS22685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BU34_RS22690	COG1045	serine acetyltransferase
BU34_RS22705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BU34_RS22710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BU34_RS22720	COG4942	peptidase
BU34_RS22725	COG2861	carbohydrate metabolic process
BU34_RS22730	COG1216	Glycosyl transferase, family 2
BU34_RS22740	COG0156	8-amino-7-oxononanoate synthase activity
BU34_RS22750	COG0859	PFAM glycosyl transferase family 9
BU34_RS22755	COG0859	PFAM glycosyl transferase family 9
BU34_RS22760	COG3307	-O-antigen
BU34_RS22765	COG3118	belongs to the thioredoxin family
BU34_RS22775	COG0045	succinate-CoA ligase (ADP-forming) activity
BU34_RS22775	COG1042	CoA-binding domain protein
BU34_RS22775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BU34_RS22780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BU34_RS22785	COG5544	Lipoprotein
BU34_RS22790	COG0477	Major facilitator Superfamily
BU34_RS22825	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BU34_RS22830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BU34_RS22850	COG0582	viral genome integration into host DNA
BU34_RS22860	COG2867	negative regulation of translational initiation
BU34_RS22870	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BU34_RS22875	COG0497	DNA recombination
BU34_RS22895	COG4536	flavin adenine dinucleotide binding
BU34_RS22900	COG4137	Cytochrome C assembly protein
BU34_RS22905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BU34_RS22930	COG2885	chlorophyll binding
BU34_RS22935	COG2199	diguanylate cyclase activity
BU34_RS22950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BU34_RS22955	COG1605	Chorismate mutase
BU34_RS22955	COG0287	Prephenate dehydrogenase
BU34_RS22960	COG1605	Chorismate mutase
BU34_RS22960	COG0077	Prephenate dehydratase
BU34_RS22965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BU34_RS22975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BU34_RS22980	COG0564	pseudouridine synthase activity
BU34_RS22985	COG1496	oxidoreductase activity
BU34_RS22990	COG0542	response to heat
BU34_RS23020	COG0477	Major facilitator Superfamily
BU34_RS23035	COG1739	Uncharacterized protein family UPF0029
BU34_RS23050	COG0183	Belongs to the thiolase family
BU34_RS23055	COG0543	2 iron, 2 sulfur cluster binding
BU34_RS23060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BU34_RS23065	COG0250	Participates in transcription elongation, termination and antitermination
BU34_RS23070	COG0084	hydrolase, TatD family'
BU34_RS23075	COG0805	protein transport
BU34_RS23080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BU34_RS23085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BU34_RS23095	COG3165	ubiquinone biosynthetic process from chorismate
BU34_RS23105	COG1322	Protein conserved in bacteria
BU34_RS23110	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BU34_RS23115	COG0412	Dienelactone hydrolase
BU34_RS23125	COG0583	DNA-binding transcription factor activity
BU34_RS23130	COG0697	spore germination
BU34_RS23135	COG0561	phosphatase activity
BU34_RS23140	COG2267	carboxylic ester hydrolase activity
BU34_RS23145	COG1280	lysine exporter protein (LysE YggA)
BU34_RS23150	COG1280	lysine exporter protein (LysE YggA)
BU34_RS23155	COG0514	ATP-dependent DNA helicase (RecQ)
BU34_RS23160	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BU34_RS23165	COG2050	protein possibly involved in aromatic compounds catabolism
BU34_RS23170	COG2962	Rard protein
BU34_RS23185	COG0598	Magnesium transport protein CorA
BU34_RS23190	COG3698	Phosphodiester glycosidase
BU34_RS23195	COG0210	DNA helicase
BU34_RS23200	COG1011	Hydrolase
BU34_RS23210	COG3159	Protein conserved in bacteria
BU34_RS23220	COG5567	small periplasmic lipoprotein
BU34_RS23230	COG3072	Adenylate cyclase
BU34_RS23240	COG1587	Uroporphyrinogen-III synthase
BU34_RS23245	COG2959	enzyme of heme biosynthesis
BU34_RS23250	COG3071	HemY protein
BU34_RS23255	COG3119	arylsulfatase activity
BU34_RS23260	COG0641	radical SAM
BU34_RS23285	COG1113	amino acid transport
BU34_RS23305	COG2244	polysaccharide biosynthetic process
BU34_RS23310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BU34_RS23315	COG0456	acetyltransferase
BU34_RS23320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BU34_RS23325	COG1088	dTDP-glucose 4,6-dehydratase activity
BU34_RS23330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BU34_RS23335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BU34_RS23340	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BU34_RS23345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BU34_RS23355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BU34_RS23365	COG3118	belongs to the thioredoxin family
BU34_RS23380	COG0210	DNA helicase
BU34_RS23400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BU34_RS23410	COG0583	DNA-binding transcription factor activity
BU34_RS23415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BU34_RS23425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BU34_RS23430	COG3978	acetolactate synthase activity
BU34_RS23445	COG0606	chelatase, subunit chli
BU34_RS23450	COG3085	chromosome segregation
BU34_RS23490	COG2186	Transcriptional regulator
BU34_RS23495	COG0477	Major facilitator Superfamily
BU34_RS23500	COG1609	Transcriptional regulator
BU34_RS23505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BU34_RS23510	COG1879	ABC-type sugar transport system periplasmic component
BU34_RS23515	COG1172	Belongs to the binding-protein-dependent transport system permease family
BU34_RS23520	COG1129	ABC transporter
BU34_RS23550	COG1522	sequence-specific DNA binding
BU34_RS23555	COG0716	FMN binding
BU34_RS23570	COG3312	ion transport
BU34_RS23625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BU34_RS23630	COG0573	inorganic phosphate transmembrane transporter activity
BU34_RS23635	COG0581	inorganic phosphate transmembrane transporter activity
BU34_RS23640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BU34_RS23645	COG0704	Plays a role in the regulation of phosphate uptake
BU34_RS23650	COG3711	transcriptional antiterminator
BU34_RS23655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BU34_RS23655	COG1263	PTS System
BU34_RS23655	COG2190	(PTS) system
BU34_RS23660	COG2723	6-phospho-beta-galactosidase activity
BU34_RS23670	COG2382	esterase
BU34_RS23675	COG0363	glucosamine-6-phosphate deaminase activity
BU34_RS23680	COG3196	Protein conserved in bacteria
BU34_RS23690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BU34_RS23695	COG2252	PERMEase
BU34_RS23700	COG0431	NADPH-dependent FMN reductase
BU34_RS23705	COG2091	lysine biosynthetic process via aminoadipic acid
BU34_RS23720	COG0814	amino acid
BU34_RS23820	COG3209	COG3209 Rhs family protein