locus-tag	class	description
CF57_RS00010	COG0592	DNA-directed DNA polymerase activity
CF57_RS00020	COG0187	DNA topoisomerase II activity
CF57_RS00030	COG3753	Protein conserved in bacteria
CF57_RS00035	COG0561	phosphatase activity
CF57_RS00045	COG2186	Transcriptional regulator
CF57_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
CF57_RS00055	COG0800	Aldolase
CF57_RS00065	COG2271	Major facilitator Superfamily
CF57_RS00075	COG0823	Involved in the tonB-independent uptake of proteins
CF57_RS00080	COG5645	(Lipo)protein
CF57_RS00100	COG2188	Transcriptional regulator
CF57_RS00120	COG0675	Transposase, IS605 OrfB family
CF57_RS00125	COG2149	membrane
CF57_RS00135	COG0641	radical SAM
CF57_RS00140	COG2814	Major facilitator Superfamily
CF57_RS00160	COG0028	Belongs to the TPP enzyme family
CF57_RS00165	COG0440	acetolactate synthase activity
CF57_RS00170	COG2197	response regulator
CF57_RS00175	COG3851	Histidine kinase
CF57_RS00180	COG2271	Major facilitator Superfamily
CF57_RS00185	COG2271	Major facilitator Superfamily
CF57_RS00195	COG2252	PERMEase
CF57_RS00220	COG1464	Belongs to the NlpA lipoprotein family
CF57_RS00225	COG0697	spore germination
CF57_RS00230	COG2814	Major facilitator Superfamily
CF57_RS00245	COG2211	Major facilitator Superfamily
CF57_RS00250	COG1501	Belongs to the glycosyl hydrolase 31 family
CF57_RS00255	COG2982	Protein involved in outer membrane biogenesis
CF57_RS00260	COG2233	PERMEase
CF57_RS00265	COG0786	glutamate:sodium symporter activity
CF57_RS00270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CF57_RS00275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CF57_RS00280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CF57_RS00290	COG0194	GDP metabolic process
CF57_RS00300	COG2860	membrane
CF57_RS00310	COG1561	YicC-like family, N-terminal region
CF57_RS00335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CF57_RS00365	COG1519	Transferase
CF57_RS00370	COG0859	PFAM glycosyl transferase family 9
CF57_RS00375	COG0438	transferase activity, transferring glycosyl groups
CF57_RS00380	COG0515	serine threonine protein kinase
CF57_RS00395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CF57_RS00400	COG1442	glycosyl transferase family 8
CF57_RS00405	COG1216	Glycosyl transferase, family 2
CF57_RS00410	COG3307	-O-antigen
CF57_RS00415	COG0859	PFAM glycosyl transferase family 9
CF57_RS00420	COG0859	PFAM glycosyl transferase family 9
CF57_RS00430	COG0156	8-amino-7-oxononanoate synthase activity
CF57_RS00440	COG1216	Glycosyl transferase, family 2
CF57_RS00445	COG2861	carbohydrate metabolic process
CF57_RS00450	COG4942	peptidase
CF57_RS00460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF57_RS00465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CF57_RS00480	COG1045	serine acetyltransferase
CF57_RS00485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CF57_RS00495	COG2186	Transcriptional regulator
CF57_RS00500	COG1620	l-lactate permease
CF57_RS00505	COG5295	Hep Hag repeat protein
CF57_RS00525	COG3722	fumarate hydratase activity
CF57_RS00535	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS00535	COG2213	PTS system mannitol-specific
CF57_RS00545	COG1566	PFAM secretion protein HlyD family protein
CF57_RS00555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CF57_RS00560	COG3209	COG3209 Rhs family protein
CF57_RS00565	COG1413	lyase activity
CF57_RS00570	COG3209	COG3209 Rhs family protein
CF57_RS00575	COG0625	glutathione transferase activity
CF57_RS00585	COG3276	selenocysteine insertion sequence binding
CF57_RS00590	COG1454	alcohol dehydrogenase
CF57_RS00595	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS00610	COG1566	PFAM secretion protein HlyD family protein
CF57_RS00615	COG0583	DNA-binding transcription factor activity
CF57_RS00620	COG3713	MltA-interacting MipA family protein
CF57_RS00630	COG2211	Major facilitator Superfamily
CF57_RS00640	COG0235	Class ii aldolase
CF57_RS00645	COG3623	hexulose-6-phosphate isomerase
CF57_RS00650	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CF57_RS00655	COG1070	Carbohydrate kinase
CF57_RS00660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CF57_RS00665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CF57_RS00670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CF57_RS00675	COG2731	YhcH YjgK YiaL family protein
CF57_RS00685	COG1414	Transcriptional regulator
CF57_RS00690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS00700	COG3977	Valine--pyruvate aminotransferase
CF57_RS00705	COG0366	Alpha amylase catalytic
CF57_RS00710	COG2992	FlgJ-related protein
CF57_RS00715	COG2207	Transcriptional regulator
CF57_RS00715	COG1609	Transcriptional regulator
CF57_RS00720	COG4214	carbohydrate transport
CF57_RS00725	COG1129	ABC transporter
CF57_RS00730	COG4213	ABC transporter substrate-binding protein
CF57_RS00740	COG1070	Carbohydrate kinase
CF57_RS00745	COG4682	membrane
CF57_RS00750	COG4682	membrane
CF57_RS00755	COG3274	enterobacterial common antigen metabolic process
CF57_RS00775	COG2963	transposase activity
CF57_RS00780	COG2801	Transposase and inactivated derivatives
CF57_RS00790	COG1278	Cold shock
CF57_RS00795	COG2944	sequence-specific DNA binding
CF57_RS00810	COG2885	chlorophyll binding
CF57_RS00815	COG0243	molybdopterin cofactor binding
CF57_RS00820	COG0456	acetyltransferase
CF57_RS00825	COG2818	Glycosylase
CF57_RS00830	COG5571	outer membrane autotransporter
CF57_RS00835	COG2223	nitrite transmembrane transporter activity
CF57_RS00840	COG2194	sulfuric ester hydrolase activity
CF57_RS00855	COG0747	negative chemotaxis
CF57_RS00865	COG0601	transmembrane transport
CF57_RS00870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF57_RS00875	COG0444	Belongs to the ABC transporter superfamily
CF57_RS00880	COG4608	Belongs to the ABC transporter superfamily
CF57_RS00885	COG0814	amino acid
CF57_RS00900	COG2194	sulfuric ester hydrolase activity
CF57_RS00940	COG1215	transferase activity, transferring glycosyl groups
CF57_RS00945	COG1215	transferase activity, transferring glycosyl groups
CF57_RS00950	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CF57_RS00955	COG0457	Tetratricopeptide repeat
CF57_RS00955	COG3118	belongs to the thioredoxin family
CF57_RS00960	COG2199	diguanylate cyclase activity
CF57_RS00960	COG2200	EAL domain
CF57_RS00970	COG0612	Peptidase, M16
CF57_RS00975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF57_RS00985	COG2200	EAL domain
CF57_RS00990	COG2982	Protein involved in outer membrane biogenesis
CF57_RS00995	COG0477	Major facilitator Superfamily
CF57_RS01000	COG1295	ribonuclease BN
CF57_RS01005	COG0583	DNA-binding transcription factor activity
CF57_RS01010	COG2197	response regulator
CF57_RS01020	COG1858	cytochrome C peroxidase
CF57_RS01035	COG1858	cytochrome C peroxidase
CF57_RS01040	COG0076	glutamate decarboxylase activity
CF57_RS01055	COG2207	Transcriptional regulator
CF57_RS01060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF57_RS01065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF57_RS01075	COG2771	luxR family
CF57_RS01080	COG3247	response to pH
CF57_RS01095	COG1285	pathogenesis
CF57_RS01100	COG2197	response regulator
CF57_RS01105	COG3065	identical protein binding
CF57_RS01115	COG1393	Belongs to the ArsC family
CF57_RS01120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CF57_RS01125	COG0640	Transcriptional regulator
CF57_RS01140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF57_RS01145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CF57_RS01150	COG0339	signal peptide processing
CF57_RS01160	COG3104	oligopeptide transport
CF57_RS01165	COG0589	response to stress
CF57_RS01175	COG0306	phosphate transporter
CF57_RS01180	COG2081	HI0933 family
CF57_RS01195	COG2801	Transposase and inactivated derivatives
CF57_RS01250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF57_RS01255	COG0842	Transport permease protein
CF57_RS01255	COG1129	ABC transporter
CF57_RS01260	COG0842	Transport permease protein
CF57_RS01265	COG5433	transposase activity
CF57_RS01280	COG3209	COG3209 Rhs family protein
CF57_RS01290	COG1124	(ABC) transporter
CF57_RS01295	COG0444	Belongs to the ABC transporter superfamily
CF57_RS01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF57_RS01305	COG0601	transmembrane transport
CF57_RS01310	COG0747	negative chemotaxis
CF57_RS01315	COG2091	lysine biosynthetic process via aminoadipic acid
CF57_RS01320	COG0628	permease
CF57_RS01325	COG0477	Major facilitator Superfamily
CF57_RS01335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CF57_RS01350	COG3714	YhhN family
CF57_RS01360	COG3776	membrane
CF57_RS01365	COG0742	ribosomal rna small subunit methyltransferase
CF57_RS01370	COG0552	protein localization to endoplasmic reticulum
CF57_RS01375	COG2884	Cell division ATP-binding protein ftsE
CF57_RS01380	COG2177	Part of the ABC transporter FtsEX involved in
CF57_RS01385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CF57_RS01390	COG0683	leucine binding
CF57_RS01400	COG0456	acetyltransferase
CF57_RS01405	COG0683	leucine binding
CF57_RS01410	COG0559	Belongs to the binding-protein-dependent transport system permease family
CF57_RS01415	COG4177	L-phenylalanine transmembrane transporter activity
CF57_RS01420	COG0411	ABC transporter
CF57_RS01425	COG0410	ABC transporter
CF57_RS01435	COG1653	transport
CF57_RS01440	COG1175	transmembrane transport
CF57_RS01445	COG0395	ABC-type sugar transport system, permease component
CF57_RS01450	COG3842	ATPase activity
CF57_RS01455	COG0584	glycerophosphoryl diester phosphodiesterase
CF57_RS01465	COG0405	Gamma-glutamyltransferase
CF57_RS01480	COG3157	Type VI secretion system effector, Hcp
CF57_RS01485	COG1247	-acetyltransferase
CF57_RS01490	COG0673	inositol 2-dehydrogenase activity
CF57_RS01495	COG1741	Belongs to the pirin family
CF57_RS01500	COG1609	Transcriptional regulator
CF57_RS01505	COG3265	gluconokinase activity
CF57_RS01510	COG2610	gluconate transmembrane transporter activity
CF57_RS01515	COG2095	MarC family integral membrane protein
CF57_RS01520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CF57_RS01545	COG0058	SHG alpha-glucan phosphorylase activity
CF57_RS01550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CF57_RS01570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CF57_RS01585	COG1349	DNA-binding transcription factor activity
CF57_RS01590	COG4650	regulator
CF57_RS01595	COG1690	Belongs to the RtcB family
CF57_RS01610	COG0058	SHG alpha-glucan phosphorylase activity
CF57_RS01615	COG1640	4-alpha-glucanotransferase
CF57_RS01620	COG2610	gluconate transmembrane transporter activity
CF57_RS01640	COG5464	transposase or invertase
CF57_RS01650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CF57_RS01655	COG1918	ferrous iron import across plasma membrane
CF57_RS01660	COG2183	response to ionizing radiation
CF57_RS01665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CF57_RS01690	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CF57_RS01700	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CF57_RS01705	COG1011	Hydrolase
CF57_RS01715	COG0494	nUDIX hydrolase
CF57_RS01720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CF57_RS01725	COG4972	Pilus assembly protein
CF57_RS01730	COG3166	PFAM Fimbrial assembly family protein
CF57_RS01745	COG4796	Type ii and iii secretion system protein
CF57_RS01760	COG3266	domain, Protein
CF57_RS01765	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CF57_RS01770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CF57_RS01775	COG0546	phosphoglycolate phosphatase activity
CF57_RS01780	COG0180	Tryptophanyl-tRNA synthetase
CF57_RS01785	COG2188	Transcriptional regulator
CF57_RS01795	COG3457	Alanine racemase
CF57_RS01800	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CF57_RS01805	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CF57_RS01820	COG0626	cystathionine gamma-synthase activity
CF57_RS01825	COG2188	Transcriptional regulator
CF57_RS01830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF57_RS01835	COG1082	Xylose isomerase domain protein TIM barrel
CF57_RS01840	COG2222	sugar isomerase
CF57_RS01845	COG0531	amino acid
CF57_RS01860	COG2116	formate transmembrane transporter activity
CF57_RS01865	COG2146	nitrite reductase [NAD(P)H] activity
CF57_RS01870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CF57_RS01880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CF57_RS01890	COG2184	nucleotidyltransferase activity
CF57_RS01895	COG0512	Glutamine amidotransferase of anthranilate synthase
CF57_RS01900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CF57_RS01905	COG1289	transmembrane transporter activity
CF57_RS01910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF57_RS01920	COG1765	OsmC-like protein
CF57_RS01925	COG3954	Phosphoribulokinase
CF57_RS01935	COG0429	hydrolase of the alpha beta-hydrolase fold
CF57_RS01940	COG0488	(ABC) transporter
CF57_RS01955	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CF57_RS01960	COG1047	Peptidyl-prolyl cis-trans
CF57_RS01970	COG0545	Peptidyl-prolyl cis-trans isomerase
CF57_RS01975	COG2964	Protein conserved in bacteria
CF57_RS02015	COG3979	chitinase
CF57_RS02020	COG2906	2 iron, 2 sulfur cluster binding
CF57_RS02025	COG2193	ferroxidase activity
CF57_RS02030	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CF57_RS02035	COG1662	PFAM IS1 transposase
CF57_RS02040	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CF57_RS02045	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CF57_RS02050	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CF57_RS02055	COG3156	type II secretion system protein K
CF57_RS02060	COG4795	General secretion pathway protein
CF57_RS02065	COG2165	general secretion pathway protein
CF57_RS02070	COG2165	general secretion pathway protein
CF57_RS02075	COG2165	general secretion pathway protein
CF57_RS02080	COG1459	type II secretion system
CF57_RS02090	COG1450	Type ii and iii secretion system protein
CF57_RS02095	COG3031	protein transport across the cell outer membrane
CF57_RS02100	COG3267	Type II secretory pathway component ExeA
CF57_RS02100	COG3409	Peptidoglycan-binding domain 1 protein
CF57_RS02125	COG0089	rRNA binding
CF57_RS02215	COG0201	protein transport
CF57_RS02255	COG0789	Transcriptional regulator
CF57_RS02260	COG3036	rescue of stalled ribosome
CF57_RS02270	COG0569	domain protein
CF57_RS02290	COG0758	DNA mediated transformation
CF57_RS02300	COG0551	DNA topoisomerase type I activity
CF57_RS02320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CF57_RS02360	COG1126	abc transporter atp-binding protein
CF57_RS02365	COG0765	amino acid transport
CF57_RS02370	COG4597	amino acid ABC transporter
CF57_RS02375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF57_RS02390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF57_RS02395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF57_RS02400	COG1309	transcriptional regulator
CF57_RS02410	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CF57_RS02420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CF57_RS02430	COG4145	pantothenate transmembrane transporter activity
CF57_RS02435	COG3924	membrane
CF57_RS02440	COG0439	Biotin carboxylase
CF57_RS02445	COG0511	ligase activity, forming carbon-carbon bonds
CF57_RS02465	COG0604	alcohol dehydrogenase
CF57_RS02470	COG2200	EAL domain
CF57_RS02470	COG2199	diguanylate cyclase activity
CF57_RS02480	COG1077	Cell shape determining protein MreB Mrl
CF57_RS02485	COG1792	Involved in formation and maintenance of cell shape
CF57_RS02490	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CF57_RS02500	COG1530	ribonuclease E activity
CF57_RS02505	COG3164	Protein of unknown function
CF57_RS02510	COG0312	modulator of DNA gyrase
CF57_RS02515	COG0583	DNA-binding transcription factor activity
CF57_RS02535	COG2732	(Barnase) inhibitor
CF57_RS02555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF57_RS02560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF57_RS02565	COG3105	Protein conserved in bacteria
CF57_RS02570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CF57_RS02585	COG0625	glutathione transferase activity
CF57_RS02590	COG2969	positive regulation of protein catabolic process
CF57_RS02595	COG3069	C4-dicarboxylate transmembrane transporter activity
CF57_RS02625	COG2731	YhcH YjgK YiaL family protein
CF57_RS02635	COG4804	nuclease activity
CF57_RS02640	COG0493	'glutamate synthase
CF57_RS02645	COG0067	glutamate synthase
CF57_RS02645	COG0069	glutamate synthase activity
CF57_RS02645	COG0070	glutamate synthase
CF57_RS02650	COG1242	4 iron, 4 sulfur cluster binding
CF57_RS02655	COG0784	Response regulator, receiver
CF57_RS02655	COG2198	Histidine kinase
CF57_RS02655	COG5002	protein histidine kinase activity
CF57_RS02660	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CF57_RS02670	COG0515	serine threonine protein kinase
CF57_RS02675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS02690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CF57_RS02695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CF57_RS02700	COG1137	ATPase activity
CF57_RS02705	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CF57_RS02710	COG3117	lipopolysaccharide transmembrane transporter activity
CF57_RS02715	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CF57_RS02720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CF57_RS02720	COG0517	IMP dehydrogenase activity
CF57_RS02725	COG0530	calcium, potassium:sodium antiporter activity
CF57_RS02730	COG1127	ABC transporter
CF57_RS02735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CF57_RS02740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CF57_RS02745	COG2854	intermembrane phospholipid transfer
CF57_RS02750	COG3113	response to antibiotic
CF57_RS02755	COG5007	Belongs to the BolA IbaG family
CF57_RS02765	COG3423	Transcriptional regulator
CF57_RS02770	COG0142	geranyltranstransferase activity
CF57_RS02785	COG0697	spore germination
CF57_RS02795	COG2027	D-alanyl-D-alanine carboxypeptidase
CF57_RS02800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CF57_RS02805	COG1534	Rna-binding protein
CF57_RS02815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CF57_RS02820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CF57_RS02830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CF57_RS02840	COG2194	sulfuric ester hydrolase activity
CF57_RS02860	COG0195	Participates in both transcription termination and antitermination
CF57_RS02895	COG0513	Belongs to the DEAD box helicase family
CF57_RS02905	COG0814	amino acid
CF57_RS02910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CF57_RS02915	COG0826	peptidase U32
CF57_RS02920	COG0826	peptidase U32
CF57_RS02925	COG3154	lipid carrier protein
CF57_RS02930	COG3153	acetyltransferase
CF57_RS02945	COG0693	protein deglycase activity
CF57_RS02950	COG0702	epimerase
CF57_RS02955	COG0701	Predicted permease
CF57_RS02960	COG2823	Periplasmic or secreted lipoprotein
CF57_RS02975	COG3107	peptidoglycan biosynthetic process
CF57_RS02980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CF57_RS02985	COG3539	Fimbrial protein
CF57_RS02990	COG3188	usher protein
CF57_RS02995	COG3121	Chaperone
CF57_RS03000	COG3539	Fimbrial protein
CF57_RS03005	COG0363	glucosamine-6-phosphate deaminase activity
CF57_RS03010	COG3716	PTS system mannose fructose sorbose family IID component
CF57_RS03015	COG3715	PTS system
CF57_RS03020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS03030	COG2222	sugar isomerase
CF57_RS03035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CF57_RS03040	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS03045	COG3716	PTS system mannose fructose sorbose family IID component
CF57_RS03055	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS03065	COG1349	DNA-binding transcription factor activity
CF57_RS03075	COG2002	toxin-antitoxin pair type II binding
CF57_RS03080	COG2721	sulfolactate sulfo-lyase activity
CF57_RS03085	COG2271	Major facilitator Superfamily
CF57_RS03095	COG2084	Dehydrogenase
CF57_RS03100	COG1929	Belongs to the glycerate kinase type-1 family
CF57_RS03120	COG0583	DNA-binding transcription factor activity
CF57_RS03125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CF57_RS03135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CF57_RS03140	COG1882	Formate acetyltransferase
CF57_RS03145	COG0251	oxidation-reduction process
CF57_RS03150	COG1760	l-serine dehydratase
CF57_RS03155	COG0814	amino acid
CF57_RS03170	COG1741	Belongs to the pirin family
CF57_RS03175	COG0583	DNA-binding transcription factor activity
CF57_RS03180	COG3152	Membrane
CF57_RS03185	COG3152	Membrane
CF57_RS03190	COG0435	Glutathione S-transferase
CF57_RS03195	COG2259	Doxx family
CF57_RS03205	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CF57_RS03210	COG4575	ribosome binding
CF57_RS03215	COG1422	Protein of unknown function (DUF1090)
CF57_RS03225	COG0586	Pfam SNARE associated Golgi protein
CF57_RS03230	COG2186	Transcriptional regulator
CF57_RS03255	COG2271	Major facilitator Superfamily
CF57_RS03265	COG2721	sulfolactate sulfo-lyase activity
CF57_RS03275	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CF57_RS03280	COG0861	Integral membrane protein TerC family
CF57_RS03285	COG0673	inositol 2-dehydrogenase activity
CF57_RS03290	COG2949	membrane
CF57_RS03295	COG1451	nucleotide metabolic process
CF57_RS03310	COG4680	protein conserved in bacteria
CF57_RS03315	COG5499	transcription regulator containing HTH domain
CF57_RS03320	COG0446	pyridine nucleotide-disulphide oxidoreductase
CF57_RS03320	COG1902	pentaerythritol trinitrate reductase activity
CF57_RS03325	COG3408	Glycogen debranching enzyme
CF57_RS03325	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CF57_RS03335	COG0531	amino acid
CF57_RS03340	COG2731	YhcH YjgK YiaL family protein
CF57_RS03345	COG3250	beta-galactosidase activity
CF57_RS03350	COG1609	Transcriptional regulator
CF57_RS03355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CF57_RS03365	COG0840	transmembrane signaling receptor activity
CF57_RS03370	COG1695	Transcriptional regulator
CF57_RS03375	COG2375	cellular response to nickel ion
CF57_RS03390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CF57_RS03395	COG0358	DNA primase activity
CF57_RS03400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CF57_RS03410	COG0471	metal ion transport
CF57_RS03415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CF57_RS03420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CF57_RS03425	COG0583	DNA-binding transcription factor activity
CF57_RS03435	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CF57_RS03450	COG4991	sh3 domain protein
CF57_RS03460	COG3025	triphosphatase activity
CF57_RS03485	COG2268	Band 7 protein
CF57_RS03490	COG1585	Membrane protein implicated in regulation of membrane protease activity
CF57_RS03500	COG3539	Fimbrial protein
CF57_RS03505	COG3121	Chaperone
CF57_RS03510	COG3188	usher protein
CF57_RS03515	COG3539	Fimbrial protein
CF57_RS03520	COG2960	long-chain fatty acid transporting porin activity
CF57_RS03540	COG3384	dioxygenase
CF57_RS03545	COG0754	glutathionylspermidine amidase activity
CF57_RS03560	COG1538	Outer membrane efflux protein
CF57_RS03565	COG0494	nUDIX hydrolase
CF57_RS03570	COG3151	Protein conserved in bacteria
CF57_RS03575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CF57_RS03580	COG3150	esterase
CF57_RS03585	COG0187	DNA topoisomerase II activity
CF57_RS03590	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CF57_RS03595	COG2249	NAD(P)H dehydrogenase (quinone) activity
CF57_RS03605	COG0642	Histidine kinase
CF57_RS03610	COG0745	RESPONSE REGULATOR receiver
CF57_RS03615	COG3111	PFAM Bacterial OB fold (BOF) protein
CF57_RS03620	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CF57_RS03630	COG2944	sequence-specific DNA binding
CF57_RS03635	COG4166	transmembrane transport
CF57_RS03640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CF57_RS03645	COG0204	Acyl-transferase
CF57_RS03650	COG2132	Multicopper oxidase
CF57_RS03655	COG1032	radical SAM domain protein
CF57_RS03660	COG4238	major outer membrane lipoprotein
CF57_RS03670	COG0656	L-ascorbic acid biosynthetic process
CF57_RS03675	COG1979	alcohol dehydrogenase
CF57_RS03685	COG2207	Transcriptional regulator
CF57_RS03690	COG0586	Pfam SNARE associated Golgi protein
CF57_RS03695	COG0626	cystathionine gamma-synthase activity
CF57_RS03705	COG0811	peptide transport
CF57_RS03710	COG0848	biopolymer transport protein
CF57_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS03725	COG0667	Aldo Keto reductase
CF57_RS03745	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CF57_RS03750	COG0437	4 iron, 4 sulfur cluster binding
CF57_RS03755	COG5557	Pfam Polysulphide reductase, NrfD
CF57_RS03760	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CF57_RS03765	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CF57_RS03770	COG1773	rubredoxin
CF57_RS03780	COG0298	carbon dioxide binding
CF57_RS03785	COG0625	glutathione transferase activity
CF57_RS03790	COG0754	glutathionylspermidine amidase activity
CF57_RS03795	COG0306	phosphate transporter
CF57_RS03800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CF57_RS03805	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CF57_RS03810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CF57_RS03815	COG2244	polysaccharide biosynthetic process
CF57_RS03825	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CF57_RS03830	COG0795	lipopolysaccharide-transporting ATPase activity
CF57_RS03840	COG0156	8-amino-7-oxononanoate synthase activity
CF57_RS03845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF57_RS03855	COG0318	PFAM AMP-dependent synthetase and ligase
CF57_RS03860	COG0456	acetyltransferase
CF57_RS03865	COG2186	Transcriptional regulator
CF57_RS03870	COG0277	FAD linked oxidase domain protein
CF57_RS03875	COG0277	FAD linked oxidase domain protein
CF57_RS03880	COG0247	lactate metabolic process
CF57_RS03885	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CF57_RS03890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CF57_RS03895	COG1620	l-lactate permease
CF57_RS03930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CF57_RS03935	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CF57_RS03945	COG1811	Na channel or pump
CF57_RS03950	COG1982	Orn Lys Arg decarboxylase major
CF57_RS03955	COG2211	Major facilitator Superfamily
CF57_RS03970	COG1194	a g-specific adenine glycosylase
CF57_RS03980	COG3171	Protein conserved in bacteria
CF57_RS03995	COG0252	asparaginase activity
CF57_RS04005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CF57_RS04020	COG0762	integral membrane protein
CF57_RS04025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CF57_RS04030	COG2805	Type II/IV secretion system protein
CF57_RS04045	COG0189	ligase activity
CF57_RS04050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CF57_RS04055	COG2356	endonuclease I
CF57_RS04065	COG2814	Major facilitator Superfamily
CF57_RS04090	COG1166	arginine decarboxylase activity
CF57_RS04100	COG0501	Belongs to the peptidase M48B family
CF57_RS04105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CF57_RS04110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS04115	COG2213	PTS system mannitol-specific
CF57_RS04120	COG1063	alcohol dehydrogenase
CF57_RS04125	COG1494	fructose-1,6-bisphosphatase
CF57_RS04130	COG3722	fumarate hydratase activity
CF57_RS04135	COG1072	(Pantothenic acid kinase))
CF57_RS04150	COG0191	fructose-bisphosphate aldolase activity
CF57_RS04155	COG0668	transmembrane transport
CF57_RS04160	COG1279	arginine transmembrane transporter activity
CF57_RS04165	COG2968	Membrane
CF57_RS04170	COG0583	DNA-binding transcription factor activity
CF57_RS04175	COG0427	acetyl-CoA hydrolase
CF57_RS04180	COG1024	Enoyl-CoA hydratase
CF57_RS04185	COG1703	isobutyryl-CoA mutase activity
CF57_RS04190	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CF57_RS04190	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CF57_RS04210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CF57_RS04215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CF57_RS04230	COG0006	proline dipeptidase activity
CF57_RS04235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CF57_RS04240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CF57_RS04260	COG2723	6-phospho-beta-galactosidase activity
CF57_RS04270	COG1272	protein, Hemolysin III
CF57_RS04280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CF57_RS04290	COG0716	FMN binding
CF57_RS04295	COG4974	Belongs to the 'phage' integrase family
CF57_RS04300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CF57_RS04305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CF57_RS04315	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CF57_RS04330	COG2233	PERMEase
CF57_RS04340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS04340	COG0493	'glutamate synthase
CF57_RS04345	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS04350	COG2252	PERMEase
CF57_RS04355	COG0402	S-adenosylhomocysteine deaminase activity
CF57_RS04370	COG2233	PERMEase
CF57_RS04375	COG2080	2 iron, 2 sulfur cluster binding
CF57_RS04375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CF57_RS04380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CF57_RS04385	COG0402	S-adenosylhomocysteine deaminase activity
CF57_RS04390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS04390	COG0493	'glutamate synthase
CF57_RS04395	COG2068	MobA-Related Protein
CF57_RS04400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CF57_RS04410	COG0549	Belongs to the carbamate kinase family
CF57_RS04420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CF57_RS04425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CF57_RS04430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CF57_RS04435	COG3829	transcription factor binding
CF57_RS04440	COG2080	2 iron, 2 sulfur cluster binding
CF57_RS04445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CF57_RS04450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CF57_RS04455	COG4942	peptidase
CF57_RS04465	COG3387	PFAM Glycoside hydrolase 15-related
CF57_RS04470	COG3387	PFAM Glycoside hydrolase 15-related
CF57_RS04540	COG2197	response regulator
CF57_RS04555	COG3710	Transcriptional regulator
CF57_RS04555	COG0457	Tetratricopeptide repeat
CF57_RS04560	COG0457	Tetratricopeptide repeat
CF57_RS04595	COG2771	luxR family
CF57_RS04600	COG0814	amino acid
CF57_RS04605	COG0183	Belongs to the thiolase family
CF57_RS04615	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS04620	COG2814	Major facilitator Superfamily
CF57_RS04625	COG1794	racemase activity, acting on amino acids and derivatives
CF57_RS04630	COG0583	DNA-binding transcription factor activity
CF57_RS04640	COG1609	Transcriptional regulator
CF57_RS04655	COG0667	Aldo Keto reductase
CF57_RS04665	COG0861	Integral membrane protein TerC family
CF57_RS04690	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CF57_RS04705	COG2165	general secretion pathway protein
CF57_RS04710	COG4795	General secretion pathway protein
CF57_RS04720	COG4967	type IV pilus modification protein PilV
CF57_RS04725	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CF57_RS04735	COG1074	ATP-dependent DNA helicase activity
CF57_RS04740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CF57_RS04745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CF57_RS04745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CF57_RS04750	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF57_RS04770	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CF57_RS04775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CF57_RS04780	COG2166	iron-sulfur cluster assembly
CF57_RS04785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CF57_RS04795	COG0583	DNA-binding transcription factor activity
CF57_RS04800	COG2363	Small membrane protein
CF57_RS04810	COG1349	DNA-binding transcription factor activity
CF57_RS04820	COG1070	Carbohydrate kinase
CF57_RS04830	COG0738	Major facilitator superfamily
CF57_RS04835	COG0235	Class ii aldolase
CF57_RS04840	COG1454	alcohol dehydrogenase
CF57_RS04850	COG1760	l-serine dehydratase
CF57_RS04855	COG0814	amino acid
CF57_RS04860	COG1611	Belongs to the LOG family
CF57_RS04880	COG3098	single-species biofilm formation
CF57_RS04885	COG0564	pseudouridine synthase activity
CF57_RS04890	COG0716	FMN binding
CF57_RS04895	COG2271	Major facilitator Superfamily
CF57_RS04900	COG4948	Mandelate Racemase Muconate Lactonizing
CF57_RS04905	COG2205	protein histidine kinase activity
CF57_RS04905	COG4999	Histidine kinase
CF57_RS04905	COG3437	response regulator, receiver
CF57_RS04905	COG3850	Histidine kinase
CF57_RS04910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CF57_RS04915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CF57_RS04920	COG2336	PFAM SpoVT AbrB
CF57_RS04925	COG2337	Toxic component of a toxin-antitoxin (TA) module
CF57_RS04930	COG3956	TIGRFAM MazG family protein
CF57_RS04945	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CF57_RS04955	COG0602	queuosine metabolic process
CF57_RS04960	COG1070	Carbohydrate kinase
CF57_RS04965	COG2223	nitrite transmembrane transporter activity
CF57_RS04970	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS04975	COG0277	FAD linked oxidase domain protein
CF57_RS04980	COG0477	Major facilitator Superfamily
CF57_RS04985	COG2086	electron transfer activity
CF57_RS04990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CF57_RS04995	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CF57_RS05000	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CF57_RS05005	COG0644	oxidoreductase
CF57_RS05010	COG0720	synthase
CF57_RS05030	COG1203	CRISPR-associated helicase, Cas3
CF57_RS05040	COG2801	Transposase and inactivated derivatives
CF57_RS05045	COG1203	CRISPR-associated helicase, Cas3
CF57_RS05060	COG1857	crispr-associated protein
CF57_RS05075	COG1518	maintenance of DNA repeat elements
CF57_RS05080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CF57_RS05085	COG2234	aminopeptidase activity
CF57_RS05140	COG1388	LysM domain
CF57_RS05140	COG4942	peptidase
CF57_RS05145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CF57_RS05150	COG2610	gluconate transmembrane transporter activity
CF57_RS05155	COG3622	Belongs to the hyi family
CF57_RS05160	COG0235	Class ii aldolase
CF57_RS05165	COG3395	kinase activity
CF57_RS05170	COG2084	Dehydrogenase
CF57_RS05175	COG1349	DNA-binding transcription factor activity
CF57_RS05180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CF57_RS05200	COG3604	Transcriptional regulator
CF57_RS05205	COG0309	Hydrogenase expression formation protein (HypE)
CF57_RS05210	COG0409	Hydrogenase expression formation protein
CF57_RS05215	COG0298	carbon dioxide binding
CF57_RS05220	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CF57_RS05225	COG0375	protein maturation
CF57_RS05240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS05245	COG0651	ATP synthesis coupled electron transport
CF57_RS05250	COG0650	Formate hydrogenlyase subunit 4
CF57_RS05255	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CF57_RS05255	COG3261	NADH dehydrogenase
CF57_RS05260	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CF57_RS05265	COG3260	NADH ubiquinone oxidoreductase 20
CF57_RS05275	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CF57_RS05280	COG2723	6-phospho-beta-galactosidase activity
CF57_RS05285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS05285	COG1263	PTS System
CF57_RS05290	COG1609	Transcriptional regulator
CF57_RS05295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS05300	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CF57_RS05320	COG0517	IMP dehydrogenase activity
CF57_RS05320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CF57_RS05325	COG1349	DNA-binding transcription factor activity
CF57_RS05330	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS05340	COG3731	PTS system glucitol sorbitol-specific IIA component
CF57_RS05345	COG3732	PTS system glucitol sorbitol-specific
CF57_RS05350	COG3730	PTS system glucitol sorbitol-specific
CF57_RS05355	COG2951	lytic endotransglycosylase activity
CF57_RS05360	COG1546	Belongs to the CinA family
CF57_RS05385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CF57_RS05415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF57_RS05420	COG1238	metal cluster binding
CF57_RS05435	COG2814	Major facilitator Superfamily
CF57_RS05440	COG1566	PFAM secretion protein HlyD family protein
CF57_RS05445	COG1846	Transcriptional regulator
CF57_RS05455	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CF57_RS05460	COG2814	Major facilitator Superfamily
CF57_RS05465	COG2113	Glycine betaine
CF57_RS05470	COG4176	ABC-type proline glycine betaine transport system permease component
CF57_RS05475	COG4175	Glycine betaine
CF57_RS05480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF57_RS05485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF57_RS05495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CF57_RS05500	COG4575	ribosome binding
CF57_RS05515	COG2916	Histone family protein nucleoid-structuring protein H-NS
CF57_RS05520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF57_RS05525	COG0640	Transcriptional regulator
CF57_RS05530	COG0401	homolog of Blt101
CF57_RS05535	COG1652	LysM domain
CF57_RS05540	COG1802	Transcriptional regulator
CF57_RS05545	COG1113	amino acid transport
CF57_RS05550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CF57_RS05555	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS05560	COG0579	oxidoreductase
CF57_RS05570	COG0366	Alpha amylase catalytic
CF57_RS05575	COG0366	Alpha amylase catalytic
CF57_RS05585	COG1662	PFAM IS1 transposase
CF57_RS05590	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CF57_RS05600	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CF57_RS05610	COG1475	DNA binding
CF57_RS05630	COG2867	negative regulation of translational initiation
CF57_RS05640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF57_RS05645	COG0497	DNA recombination
CF57_RS05660	COG4536	flavin adenine dinucleotide binding
CF57_RS05665	COG4137	Cytochrome C assembly protein
CF57_RS05670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CF57_RS05695	COG2885	chlorophyll binding
CF57_RS05700	COG2199	diguanylate cyclase activity
CF57_RS05715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CF57_RS05720	COG1605	Chorismate mutase
CF57_RS05720	COG0287	Prephenate dehydrogenase
CF57_RS05725	COG1605	Chorismate mutase
CF57_RS05725	COG0077	Prephenate dehydratase
CF57_RS05730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CF57_RS05740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF57_RS05745	COG0564	pseudouridine synthase activity
CF57_RS05750	COG1496	oxidoreductase activity
CF57_RS05755	COG0542	response to heat
CF57_RS05785	COG0477	Major facilitator Superfamily
CF57_RS05790	COG0477	Major facilitator Superfamily
CF57_RS05795	COG5544	Lipoprotein
CF57_RS05805	COG0045	succinate-CoA ligase (ADP-forming) activity
CF57_RS05805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF57_RS05805	COG1042	CoA-binding domain protein
CF57_RS05810	COG3148	PFAM DTW domain containing protein
CF57_RS05815	COG3118	belongs to the thioredoxin family
CF57_RS05825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CF57_RS05845	COG0583	DNA-binding transcription factor activity
CF57_RS05855	COG0513	Belongs to the DEAD box helicase family
CF57_RS05865	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CF57_RS05875	COG1595	DNA-templated transcription, initiation
CF57_RS05880	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CF57_RS05885	COG3026	antisigma factor binding
CF57_RS05890	COG3086	response to oxidative stress
CF57_RS05900	COG0681	Belongs to the peptidase S26 family
CF57_RS05920	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CF57_RS05945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS05950	COG1737	Transcriptional regulator
CF57_RS05955	COG0560	Phosphoserine phosphatase
CF57_RS05975	COG2205	protein histidine kinase activity
CF57_RS05980	COG3170	Tfp pilus assembly protein FimV
CF57_RS05985	COG2204	response regulator
CF57_RS05990	COG0347	Belongs to the P(II) protein family
CF57_RS05995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF57_RS05995	COG1017	nitric oxide dioxygenase activity
CF57_RS06005	COG1940	carbohydrate kinase activity
CF57_RS06010	COG0457	Tetratricopeptide repeat
CF57_RS06015	COG1879	ABC-type sugar transport system periplasmic component
CF57_RS06020	COG1129	ABC transporter
CF57_RS06025	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF57_RS06030	COG1063	alcohol dehydrogenase
CF57_RS06035	COG2017	converts alpha-aldose to the beta-anomer
CF57_RS06040	COG2259	Doxx family
CF57_RS06065	COG4638	Rieske (2fe-2S)
CF57_RS06070	COG0583	DNA-binding transcription factor activity
CF57_RS06075	COG2814	Major facilitator Superfamily
CF57_RS06080	COG3711	transcriptional antiterminator
CF57_RS06085	COG1073	alpha beta
CF57_RS06090	COG0483	inositol monophosphate 1-phosphatase activity
CF57_RS06110	COG0822	iron-sulfur transferase activity
CF57_RS06130	COG0633	Ferredoxin
CF57_RS06135	COG2975	iron-sulfur cluster assembly
CF57_RS06150	COG2897	thiosulfate sulfurtransferase activity
CF57_RS06155	COG2373	Large extracellular alpha-helical protein
CF57_RS06160	COG4953	penicillin-binding protein 1C
CF57_RS06190	COG2976	Protein conserved in bacteria
CF57_RS06205	COG1645	bacterial-type flagellum-dependent swarming motility
CF57_RS06215	COG0517	IMP dehydrogenase activity
CF57_RS06215	COG0516	GMP reductase activity
CF57_RS06230	COG3133	Outer membrane lipoprotein
CF57_RS06245	COG2200	EAL domain
CF57_RS06250	COG0248	Ppx GppA phosphatase
CF57_RS06255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CF57_RS06260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CF57_RS06275	COG2233	PERMEase
CF57_RS06285	COG1393	Belongs to the ArsC family
CF57_RS06290	COG4783	chaperone-mediated protein folding
CF57_RS06295	COG0628	permease
CF57_RS06300	COG2116	formate transmembrane transporter activity
CF57_RS06305	COG3604	Transcriptional regulator
CF57_RS06315	COG3260	NADH ubiquinone oxidoreductase 20
CF57_RS06320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CF57_RS06325	COG3261	NADH dehydrogenase
CF57_RS06325	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CF57_RS06330	COG0651	ATP synthesis coupled electron transport
CF57_RS06335	COG4237	Hydrogenase 4 membrane
CF57_RS06340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CF57_RS06345	COG0650	Formate hydrogenlyase subunit 4
CF57_RS06350	COG0651	ATP synthesis coupled electron transport
CF57_RS06355	COG0651	ATP synthesis coupled electron transport
CF57_RS06360	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS06365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CF57_RS06370	COG2716	regulation of RNA biosynthetic process
CF57_RS06380	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CF57_RS06395	COG2321	neutral zinc metallopeptidase
CF57_RS06405	COG0400	carboxylic ester hydrolase activity
CF57_RS06420	COG1393	Belongs to the ArsC family
CF57_RS06430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF57_RS06435	COG3850	Histidine kinase
CF57_RS06440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS06440	COG0493	'glutamate synthase
CF57_RS06450	COG5342	invasion associated locus B
CF57_RS06455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CF57_RS06460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CF57_RS06465	COG0281	malic enzyme
CF57_RS06465	COG0280	phosphate acetyltransferase
CF57_RS06470	COG4810	utilization protein
CF57_RS06475	COG4917	ethanolamine utilization protein
CF57_RS06480	COG4766	ethanolamine catabolic process
CF57_RS06485	COG4812	Cobalamin adenosyltransferase
CF57_RS06490	COG0280	phosphate acetyltransferase
CF57_RS06495	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CF57_RS06500	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CF57_RS06505	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS06510	COG4820	ethanolamine utilization protein (EutJ)
CF57_RS06515	COG1454	alcohol dehydrogenase
CF57_RS06520	COG3192	ethanolamine utilization protein
CF57_RS06525	COG4819	ethanolamine utilization protein
CF57_RS06530	COG4303	Ethanolamine ammonia lyase large subunit
CF57_RS06540	COG4816	utilization protein
CF57_RS06545	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CF57_RS06550	COG2207	Transcriptional regulator
CF57_RS06560	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF57_RS06565	COG0456	acetyltransferase
CF57_RS06580	COG2837	iron assimilation
CF57_RS06585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF57_RS06590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS06590	COG1263	PTS System
CF57_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS06610	COG4150	thiosulfate binding
CF57_RS06615	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CF57_RS06620	COG4208	sulfate ABC transporter
CF57_RS06625	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CF57_RS06630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CF57_RS06635	COG4884	unkown
CF57_RS06635	COG3831	ATPase activity
CF57_RS06650	COG2190	(PTS) system
CF57_RS06655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF57_RS06660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS06665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CF57_RS06685	COG3530	Putative quorum-sensing-regulated virulence factor
CF57_RS06690	COG0385	Bile acid
CF57_RS06695	COG0583	DNA-binding transcription factor activity
CF57_RS06705	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CF57_RS06710	COG2211	Major facilitator Superfamily
CF57_RS06720	COG0583	DNA-binding transcription factor activity
CF57_RS06750	COG3415	Transposase
CF57_RS06755	COG3415	Transposase
CF57_RS06770	COG2199	diguanylate cyclase activity
CF57_RS06770	COG2200	EAL domain
CF57_RS06775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CF57_RS06805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS06810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS06815	COG0006	proline dipeptidase activity
CF57_RS06820	COG1363	Peptidase, m42
CF57_RS06825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF57_RS06825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS06825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS06830	COG2207	Transcriptional regulator
CF57_RS06835	COG3279	Response regulator of the LytR AlgR family
CF57_RS06840	COG3275	phosphorelay sensor kinase activity
CF57_RS06845	COG0436	Aminotransferase
CF57_RS06850	COG1560	Kdo2-lipid A biosynthetic process
CF57_RS06880	COG0028	Belongs to the TPP enzyme family
CF57_RS06885	COG0679	Auxin Efflux Carrier
CF57_RS06890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CF57_RS06895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF57_RS06895	COG0784	Response regulator, receiver
CF57_RS06895	COG2205	protein histidine kinase activity
CF57_RS06895	COG2198	Histidine kinase
CF57_RS06900	COG2197	response regulator
CF57_RS06905	COG1566	PFAM secretion protein HlyD family protein
CF57_RS06910	COG0477	Major facilitator Superfamily
CF57_RS06920	COG2610	gluconate transmembrane transporter activity
CF57_RS06925	COG0583	DNA-binding transcription factor activity
CF57_RS07105	COG3772	lysozyme
CF57_RS07125	COG1783	phage Terminase large subunit
CF57_RS07130	COG3567	Phage-associated protein, HI1409 family
CF57_RS07285	COG0582	viral genome integration into host DNA
CF57_RS07295	COG2116	formate transmembrane transporter activity
CF57_RS07300	COG2853	Lipoprotein
CF57_RS07310	COG2067	long-chain fatty acid transport protein
CF57_RS07315	COG3691	Protein conserved in bacteria
CF57_RS07330	COG2062	phosphohistidine phosphatase, SixA
CF57_RS07335	COG3539	Fimbrial protein
CF57_RS07340	COG3188	usher protein
CF57_RS07345	COG3121	Chaperone
CF57_RS07350	COG3539	Fimbrial protein
CF57_RS07355	COG3539	Fimbrial protein
CF57_RS07360	COG3539	Fimbrial protein
CF57_RS07390	COG0730	response to heat
CF57_RS07395	COG3101	peptidyl-lysine hydroxylation
CF57_RS07410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CF57_RS07415	COG2814	Major facilitator Superfamily
CF57_RS07430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CF57_RS07440	COG0586	Pfam SNARE associated Golgi protein
CF57_RS07450	COG0285	dihydrofolate synthase activity
CF57_RS07455	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CF57_RS07460	COG1286	toxin biosynthetic process
CF57_RS07465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CF57_RS07470	COG0163	prenyltransferase activity
CF57_RS07475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF57_RS07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF57_RS07485	COG4215	(ABC) transporter
CF57_RS07490	COG4160	amino acid transport
CF57_RS07495	COG4598	ABC transporter
CF57_RS07505	COG1090	epimerase
CF57_RS07510	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CF57_RS07515	COG0625	glutathione transferase activity
CF57_RS07520	COG0625	glutathione transferase activity
CF57_RS07525	COG0622	Phosphoesterase
CF57_RS07530	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CF57_RS07535	COG1288	antiporter activity
CF57_RS07540	COG0280	phosphate acetyltransferase
CF57_RS07540	COG0857	belongs to the CobB CobQ family
CF57_RS07545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CF57_RS07565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF57_RS07570	COG0490	domain, Protein
CF57_RS07570	COG0471	metal ion transport
CF57_RS07580	COG0436	Aminotransferase
CF57_RS07585	COG0583	DNA-binding transcription factor activity
CF57_RS07605	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CF57_RS07610	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CF57_RS07630	COG0839	Belongs to the complex I subunit 6 family
CF57_RS07640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CF57_RS07645	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CF57_RS07660	COG2234	aminopeptidase activity
CF57_RS07675	COG2153	protein acetylation
CF57_RS07680	COG4575	ribosome binding
CF57_RS07685	COG1169	isochorismate synthase
CF57_RS07700	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CF57_RS07710	COG0318	PFAM AMP-dependent synthetase and ligase
CF57_RS07775	COG1414	Transcriptional regulator
CF57_RS07795	COG5464	transposase or invertase
CF57_RS07800	COG0247	lactate metabolic process
CF57_RS07810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CF57_RS07815	COG2271	Major facilitator Superfamily
CF57_RS07820	COG0584	glycerophosphoryl diester phosphodiesterase
CF57_RS07825	COG0583	DNA-binding transcription factor activity
CF57_RS07830	COG3642	lipopolysaccharide core region biosynthetic process
CF57_RS07835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF57_RS07840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF57_RS07845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF57_RS07855	COG3468	outer membrane autotransporter barrel domain protein
CF57_RS07865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CF57_RS07870	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CF57_RS07875	COG3234	Protein of unknown function (DUF1175)
CF57_RS07880	COG2373	Large extracellular alpha-helical protein
CF57_RS07885	COG5445	Predicted secreted protein (DUF2300)
CF57_RS07890	COG4676	Protein conserved in bacteria
CF57_RS07895	COG2205	protein histidine kinase activity
CF57_RS07895	COG0784	Response regulator, receiver
CF57_RS07900	COG2197	response regulator
CF57_RS07905	COG0642	Histidine kinase
CF57_RS07905	COG2198	Histidine kinase
CF57_RS07920	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF57_RS07925	COG1477	protein flavinylation
CF57_RS07930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CF57_RS07930	COG2169	Transcriptional regulator
CF57_RS07935	COG3145	DNA-N1-methyladenine dioxygenase activity
CF57_RS07940	COG4615	Cyclic peptide transporter
CF57_RS07960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS07960	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF57_RS07965	COG3062	negative regulation of establishment of protein localization
CF57_RS07975	COG0437	4 iron, 4 sulfur cluster binding
CF57_RS07980	COG0348	domain, Protein
CF57_RS07985	COG3043	anaerobic respiration
CF57_RS07990	COG3005	denitrification pathway
CF57_RS08000	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CF57_RS08005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CF57_RS08010	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CF57_RS08020	COG1138	Cytochrome C-type biogenesis protein
CF57_RS08025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF57_RS08030	COG3088	subunit of a heme lyase
CF57_RS08030	COG4235	cytochrome complex assembly
CF57_RS08035	COG2197	response regulator
CF57_RS08055	COG3083	sulfuric ester hydrolase activity
CF57_RS08075	COG1061	Type III restriction enzyme res subunit
CF57_RS08080	COG1187	pseudouridine synthase activity
CF57_RS08085	COG2814	Major facilitator Superfamily
CF57_RS08095	COG4172	Belongs to the ABC transporter superfamily
CF57_RS08100	COG4239	(ABC) transporter, permease
CF57_RS08105	COG4174	ABC transporter (Permease)
CF57_RS08110	COG4166	transmembrane transport
CF57_RS08115	COG2200	EAL domain
CF57_RS08120	COG0791	NLP P60 protein
CF57_RS08125	COG0671	phosphoesterase, PA-phosphatase related
CF57_RS08130	COG0523	cobalamin synthesis protein
CF57_RS08135	COG0246	Mannitol dehydrogenase
CF57_RS08150	COG2814	Major facilitator Superfamily
CF57_RS08155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS08155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS08160	COG1105	Belongs to the carbohydrate kinase PfkB family
CF57_RS08165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS08165	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CF57_RS08165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS08170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF57_RS08175	COG2313	pseudouridylate synthase activity
CF57_RS08180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CF57_RS08185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF57_RS08195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CF57_RS08200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF57_RS08200	COG1522	sequence-specific DNA binding
CF57_RS08210	COG2855	membrane
CF57_RS08215	COG0583	DNA-binding transcription factor activity
CF57_RS08220	COG0833	amino acid
CF57_RS08225	COG4771	TonB-dependent receptor
CF57_RS08245	COG2311	Membrane
CF57_RS08255	COG1609	Transcriptional regulator
CF57_RS08260	COG1879	ABC-type sugar transport system periplasmic component
CF57_RS08265	COG1129	ABC transporter
CF57_RS08270	COG4211	Belongs to the binding-protein-dependent transport system permease family
CF57_RS08275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CF57_RS08275	COG0167	dihydroorotate dehydrogenase activity
CF57_RS08280	COG0493	'glutamate synthase
CF57_RS08290	COG2949	membrane
CF57_RS08300	COG1346	cytolysis
CF57_RS08310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CF57_RS08325	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS08330	COG0586	Pfam SNARE associated Golgi protein
CF57_RS08340	COG1686	Belongs to the peptidase S11 family
CF57_RS08345	COG0277	FAD linked oxidase domain protein
CF57_RS08350	COG1472	Belongs to the glycosyl hydrolase 3 family
CF57_RS08355	COG1732	Glycine betaine
CF57_RS08360	COG1174	glycine betaine transport
CF57_RS08365	COG1125	glycine betaine transport
CF57_RS08370	COG1174	glycine betaine transport
CF57_RS08380	COG0789	Transcriptional regulator
CF57_RS08385	COG3275	phosphorelay sensor kinase activity
CF57_RS08390	COG3279	Response regulator of the LytR AlgR family
CF57_RS08395	COG4807	Protein conserved in bacteria
CF57_RS08400	COG4808	Protein conserved in bacteria
CF57_RS08405	COG4715	Zinc finger, swim domain protein
CF57_RS08410	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CF57_RS08415	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CF57_RS08420	COG0714	Associated with various cellular activities
CF57_RS08430	COG3831	ATPase activity
CF57_RS08435	COG3831	ATPase activity
CF57_RS08445	COG0489	protein tyrosine kinase activity
CF57_RS08460	COG3539	Fimbrial protein
CF57_RS08470	COG3121	Chaperone
CF57_RS08475	COG3188	usher protein
CF57_RS08480	COG3539	Fimbrial protein
CF57_RS08485	COG5455	response to cobalt ion
CF57_RS08490	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CF57_RS08505	COG0351	phosphomethylpyrimidine kinase
CF57_RS08510	COG3757	hydrolase, family 25
CF57_RS08515	COG2188	Transcriptional regulator
CF57_RS08520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF57_RS08525	COG1397	ADP-ribosylglycohydrolase
CF57_RS08530	COG2211	Major facilitator Superfamily
CF57_RS08535	COG1830	Aldolase
CF57_RS08550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS08560	COG3775	system Galactitol-specific IIC component
CF57_RS08565	COG1063	alcohol dehydrogenase
CF57_RS08570	COG1662	PFAM IS1 transposase
CF57_RS08575	COG1063	alcohol dehydrogenase
CF57_RS08600	COG0826	peptidase U32
CF57_RS08615	COG0745	RESPONSE REGULATOR receiver
CF57_RS08620	COG2205	protein histidine kinase activity
CF57_RS08645	COG4245	von Willebrand factor, type A
CF57_RS08655	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CF57_RS08660	COG0443	Heat shock 70 kDa protein
CF57_RS08665	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CF57_RS08670	COG5001	Diguanylate cyclase
CF57_RS08670	COG3447	MASE1 domain protein
CF57_RS08670	COG5002	protein histidine kinase activity
CF57_RS08675	COG0572	uridine kinase
CF57_RS08685	COG2982	Protein involved in outer membrane biogenesis
CF57_RS08700	COG1253	flavin adenine dinucleotide binding
CF57_RS08725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CF57_RS08790	COG0438	transferase activity, transferring glycosyl groups
CF57_RS08800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CF57_RS08800	COG0140	phosphoribosyl-ATP diphosphatase activity
CF57_RS08815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CF57_RS08820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CF57_RS08820	COG0131	Imidazoleglycerol-phosphate dehydratase
CF57_RS08840	COG2161	toxin-antitoxin pair type II binding
CF57_RS08845	COG4115	mRNA cleavage
CF57_RS08850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF57_RS08855	COG0583	DNA-binding transcription factor activity
CF57_RS08860	COG0531	amino acid
CF57_RS08865	COG2391	methyltransferase activity
CF57_RS08870	COG0425	Belongs to the sulfur carrier protein TusA family
CF57_RS08875	COG2925	Exonuclease
CF57_RS08880	COG1686	Belongs to the peptidase S11 family
CF57_RS08890	COG1289	transmembrane transporter activity
CF57_RS08900	COG4917	ethanolamine utilization protein
CF57_RS08940	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CF57_RS08955	COG1376	ErfK ybiS ycfS ynhG family protein
CF57_RS08965	COG0583	DNA-binding transcription factor activity
CF57_RS08970	COG0583	DNA-binding transcription factor activity
CF57_RS08995	COG0217	transcriptional regulatory protein
CF57_RS09000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CF57_RS09005	COG0477	Major facilitator Superfamily
CF57_RS09015	COG1388	LysM domain
CF57_RS09015	COG2373	Large extracellular alpha-helical protein
CF57_RS09015	COG4932	domain protein
CF57_RS09040	COG3038	cytochrome b561
CF57_RS09045	COG3443	Belongs to the bacterial solute-binding protein 9 family
CF57_RS09060	COG2351	hydroxyisourate hydrolase activity
CF57_RS09065	COG0745	RESPONSE REGULATOR receiver
CF57_RS09070	COG2205	protein histidine kinase activity
CF57_RS09085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF57_RS09100	COG1418	mRNA catabolic process
CF57_RS09105	COG0270	DNA (cytosine-5-)-methyltransferase activity
CF57_RS09110	COG3727	T/G mismatch-specific endonuclease activity
CF57_RS09115	COG0697	spore germination
CF57_RS09120	COG2354	Protein conserved in bacteria
CF57_RS09125	COG5475	Uncharacterized small protein (DUF2158)
CF57_RS09155	COG1662	PFAM IS1 transposase
CF57_RS09170	COG2076	Multidrug Resistance protein
CF57_RS09175	COG1881	PFAM PEBP family protein
CF57_RS09180	COG2207	Transcriptional regulator
CF57_RS09195	COG0675	Transposase, IS605 OrfB family
CF57_RS09200	COG2135	peptidase activity
CF57_RS09205	COG0425	Belongs to the sulfur carrier protein TusA family
CF57_RS09210	COG2391	methyltransferase activity
CF57_RS09220	COG0366	Alpha amylase catalytic
CF57_RS09230	COG1516	flagellar protein fliS
CF57_RS09235	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CF57_RS09245	COG1191	sigma factor activity
CF57_RS09255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF57_RS09265	COG0765	amino acid transport
CF57_RS09270	COG1126	abc transporter atp-binding protein
CF57_RS09275	COG2197	response regulator
CF57_RS09290	COG2197	response regulator
CF57_RS09320	COG3012	SEC-C Motif Domain Protein
CF57_RS09320	COG3318	Belongs to the UPF0149 family
CF57_RS09325	COG0814	amino acid
CF57_RS09335	COG1528	Iron-storage protein
CF57_RS09355	COG1528	Iron-storage protein
CF57_RS09360	COG1879	ABC-type sugar transport system periplasmic component
CF57_RS09365	COG1129	ABC transporter
CF57_RS09370	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF57_RS09375	COG1877	trehalose-phosphatase activity
CF57_RS09385	COG0589	response to stress
CF57_RS09400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CF57_RS09405	COG1360	Flagellar Motor Protein
CF57_RS09410	COG2198	Histidine kinase
CF57_RS09410	COG0643	Histidine kinase
CF57_RS09420	COG0840	transmembrane signaling receptor activity
CF57_RS09430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CF57_RS09440	COG0745	RESPONSE REGULATOR receiver
CF57_RS09445	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CF57_RS09455	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CF57_RS09465	COG3755	Protein conserved in bacteria
CF57_RS09475	COG3102	Protein conserved in bacteria
CF57_RS09485	COG3005	denitrification pathway
CF57_RS09490	COG0243	molybdopterin cofactor binding
CF57_RS09505	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CF57_RS09510	COG1801	Protein of unknown function DUF72
CF57_RS09590	COG1335	isochorismatase
CF57_RS09600	COG0494	nUDIX hydrolase
CF57_RS09605	COG0217	transcriptional regulatory protein
CF57_RS09630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CF57_RS09640	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CF57_RS09645	COG0739	heme binding
CF57_RS09650	COG1560	Kdo2-lipid A biosynthetic process
CF57_RS09655	COG0469	pyruvate kinase activity
CF57_RS09660	COG1737	Transcriptional regulator
CF57_RS09670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CF57_RS09675	COG0129	dihydroxy-acid dehydratase activity
CF57_RS09680	COG0800	Aldolase
CF57_RS09690	COG3141	response to X-ray
CF57_RS09705	COG2979	Protein of unknown function (DUF533)
CF57_RS09710	COG1770	oligopeptidase
CF57_RS09715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CF57_RS09720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CF57_RS09730	COG2372	response to copper ion
CF57_RS09735	COG1276	copper resistance
CF57_RS09750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CF57_RS09770	COG3008	intermembrane lipid transfer
CF57_RS09775	COG2995	paraquat-inducible protein a
CF57_RS09780	COG1956	GAF domain-containing protein
CF57_RS09790	COG0793	Belongs to the peptidase S41A family
CF57_RS09800	COG2814	Major facilitator Superfamily
CF57_RS09805	COG1414	Transcriptional regulator
CF57_RS09840	COG2226	methyltransferase
CF57_RS09860	COG3716	PTS system mannose fructose sorbose family IID component
CF57_RS09865	COG3715	PTS system
CF57_RS09870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS09870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS09880	COG1253	flavin adenine dinucleotide binding
CF57_RS09885	COG2200	EAL domain
CF57_RS09890	COG1760	l-serine dehydratase
CF57_RS09900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CF57_RS09920	COG0251	oxidation-reduction process
CF57_RS09925	COG1199	ATP-dependent helicase activity
CF57_RS09930	COG1214	PFAM Peptidase M22, glycoprotease
CF57_RS09935	COG3065	identical protein binding
CF57_RS09940	COG0318	PFAM AMP-dependent synthetase and ligase
CF57_RS09945	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CF57_RS09950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF57_RS09955	COG4638	Rieske (2fe-2S)
CF57_RS09960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CF57_RS09965	COG0473	3-isopropylmalate dehydrogenase activity
CF57_RS09970	COG0583	DNA-binding transcription factor activity
CF57_RS09980	COG3615	Tellurite resistance protein tehB
CF57_RS09990	COG2261	transglycosylase associated protein
CF57_RS10000	COG2203	Gaf domain
CF57_RS10000	COG2199	diguanylate cyclase activity
CF57_RS10005	COG3042	response to heat
CF57_RS10010	COG3189	MarR family transcriptional regulator
CF57_RS10015	COG2807	transmembrane transport
CF57_RS10020	COG2207	Transcriptional regulator
CF57_RS10035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CF57_RS10040	COG2199	diguanylate cyclase activity
CF57_RS10045	COG2199	diguanylate cyclase activity
CF57_RS10055	COG2766	serine protein kinase
CF57_RS10060	COG3713	MltA-interacting MipA family protein
CF57_RS10065	COG0656	L-ascorbic acid biosynthetic process
CF57_RS10070	COG0676	glucose-6-phosphate 1-epimerase activity
CF57_RS10075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CF57_RS10085	COG3139	Protein of unknown function (DUF1315)
CF57_RS10090	COG1063	alcohol dehydrogenase
CF57_RS10095	COG2271	Major facilitator Superfamily
CF57_RS10100	COG1662	PFAM IS1 transposase
CF57_RS10105	COG0667	Aldo Keto reductase
CF57_RS10110	COG1349	DNA-binding transcription factor activity
CF57_RS10115	COG2814	Major facilitator Superfamily
CF57_RS10120	COG1335	isochorismatase
CF57_RS10125	COG0252	asparaginase activity
CF57_RS10130	COG0616	signal peptide processing
CF57_RS10140	COG0778	Nitroreductase
CF57_RS10155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CF57_RS10160	COG0443	Heat shock 70 kDa protein
CF57_RS10165	COG0484	heat shock protein binding
CF57_RS10170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CF57_RS10180	COG0494	nUDIX hydrolase
CF57_RS10185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CF57_RS10190	COG2897	thiosulfate sulfurtransferase activity
CF57_RS10195	COG4136	ATPase activity
CF57_RS10200	COG4135	transport system, permease component
CF57_RS10205	COG4134	Bacterial extracellular solute-binding protein
CF57_RS10210	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CF57_RS10215	COG0398	Pfam SNARE associated Golgi protein
CF57_RS10225	COG0398	Pfam SNARE associated Golgi protein
CF57_RS10230	COG0708	Exodeoxyribonuclease III
CF57_RS10260	COG3678	ATP-independent chaperone mediated protein folding
CF57_RS10270	COG0322	excinuclease ABC activity
CF57_RS10285	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF57_RS10290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF57_RS10295	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF57_RS10300	COG1447	Phosphotransferase system cellobiose-specific component IIA
CF57_RS10305	COG2169	Transcriptional regulator
CF57_RS10305	COG1917	Cupin 2, conserved barrel domain protein
CF57_RS10310	COG1486	melibiose metabolic process
CF57_RS10320	COG0753	catalase activity
CF57_RS10345	COG1823	symporter activity
CF57_RS10350	COG1988	membrane-bound metal-dependent
CF57_RS10355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF57_RS10365	COG3001	Fructosamine kinase
CF57_RS10375	COG1105	Belongs to the carbohydrate kinase PfkB family
CF57_RS10380	COG3137	Salt-induced outer membrane protein
CF57_RS10395	COG1662	PFAM IS1 transposase
CF57_RS10450	COG0386	Belongs to the glutathione peroxidase family
CF57_RS10460	COG0791	NLP P60 protein
CF57_RS10465	COG2200	EAL domain
CF57_RS10475	COG4256	Hemin uptake protein
CF57_RS10480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CF57_RS10495	COG0574	Belongs to the PEP-utilizing enzyme family
CF57_RS10495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF57_RS10500	COG0318	PFAM AMP-dependent synthetase and ligase
CF57_RS10505	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CF57_RS10510	COG0644	oxidoreductase
CF57_RS10515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CF57_RS10520	COG2086	electron transfer activity
CF57_RS10530	COG1917	Cupin 2, conserved barrel domain protein
CF57_RS10530	COG2207	Transcriptional regulator
CF57_RS10535	COG1960	acyl-CoA dehydrogenase activity
CF57_RS10540	COG4670	ketone body catabolic process
CF57_RS10555	COG2271	Major facilitator Superfamily
CF57_RS10560	COG0738	Major facilitator superfamily
CF57_RS10570	COG0628	permease
CF57_RS10575	COG0277	FAD linked oxidase domain protein
CF57_RS10575	COG0247	lactate metabolic process
CF57_RS10580	COG2050	protein possibly involved in aromatic compounds catabolism
CF57_RS10590	COG0316	Belongs to the HesB IscA family
CF57_RS10595	COG0719	Fe-S assembly protein
CF57_RS10600	COG0396	ATPase activity
CF57_RS10605	COG0719	Fe-S assembly protein
CF57_RS10620	COG1376	ErfK ybiS ycfS ynhG family protein
CF57_RS10625	COG4238	major outer membrane lipoprotein
CF57_RS10630	COG0469	pyruvate kinase activity
CF57_RS10640	COG0437	4 iron, 4 sulfur cluster binding
CF57_RS10645	COG2414	aldehyde ferredoxin oxidoreductase
CF57_RS10655	COG0437	4 iron, 4 sulfur cluster binding
CF57_RS10660	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CF57_RS10670	COG4529	Protein conserved in bacteria
CF57_RS10690	COG3468	outer membrane autotransporter barrel domain protein
CF57_RS10700	COG0307	riboflavin synthase, alpha
CF57_RS10705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CF57_RS10710	COG2814	Major facilitator Superfamily
CF57_RS10715	COG0583	DNA-binding transcription factor activity
CF57_RS10730	COG2814	Major facilitator Superfamily
CF57_RS10735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CF57_RS10740	COG0791	NLP P60 protein
CF57_RS10745	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CF57_RS10750	COG1201	RNA secondary structure unwinding
CF57_RS10760	COG0346	lactoylglutathione lyase activity
CF57_RS10765	COG1902	pentaerythritol trinitrate reductase activity
CF57_RS10770	COG1309	transcriptional regulator
CF57_RS10775	COG3313	Fe-S protein
CF57_RS10780	COG4989	oxidoreductase activity
CF57_RS10785	COG2032	superoxide dismutase activity
CF57_RS10790	COG1289	transmembrane transporter activity
CF57_RS10795	COG1566	PFAM secretion protein HlyD family protein
CF57_RS10810	COG3133	Outer membrane lipoprotein
CF57_RS10820	COG3895	Periplasmic Protein
CF57_RS10835	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CF57_RS10840	COG0625	glutathione transferase activity
CF57_RS10845	COG3104	oligopeptide transport
CF57_RS10855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CF57_RS10865	COG4659	FMN binding
CF57_RS10905	COG0673	inositol 2-dehydrogenase activity
CF57_RS10915	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CF57_RS10920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS10920	COG1263	PTS System
CF57_RS10925	COG1609	Transcriptional regulator
CF57_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS10935	COG1309	transcriptional regulator
CF57_RS10940	COG3250	beta-galactosidase activity
CF57_RS10965	COG5339	Protein conserved in bacteria
CF57_RS10970	COG1482	cell wall glycoprotein biosynthetic process
CF57_RS10975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CF57_RS10975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CF57_RS10980	COG0114	fumarate hydratase activity
CF57_RS10990	COG2205	protein histidine kinase activity
CF57_RS10995	COG0745	RESPONSE REGULATOR receiver
CF57_RS11000	COG3136	membrane protein required for alginate biosynthesis
CF57_RS11010	COG0531	amino acid
CF57_RS11020	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CF57_RS11025	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CF57_RS11030	COG0628	permease
CF57_RS11045	COG3591	Belongs to the peptidase S1B family
CF57_RS11060	COG2814	Major facilitator Superfamily
CF57_RS11065	COG0583	DNA-binding transcription factor activity
CF57_RS11070	COG1940	carbohydrate kinase activity
CF57_RS11075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CF57_RS11085	COG3381	protein complex oligomerization
CF57_RS11090	COG3302	dmso reductase anchor subunit
CF57_RS11095	COG0437	4 iron, 4 sulfur cluster binding
CF57_RS11100	COG0243	molybdopterin cofactor binding
CF57_RS11105	COG0243	molybdopterin cofactor binding
CF57_RS11120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF57_RS11135	COG4948	Mandelate Racemase Muconate Lactonizing
CF57_RS11140	COG1063	alcohol dehydrogenase
CF57_RS11145	COG0582	viral genome integration into host DNA
CF57_RS11155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CF57_RS11170	COG1403	HNH endonuclease
CF57_RS11175	COG0484	heat shock protein binding
CF57_RS11180	COG1278	Cold shock
CF57_RS11185	COG1278	Cold shock
CF57_RS11200	COG3772	lysozyme
CF57_RS11210	COG1278	Cold shock
CF57_RS11245	COG4220	transposase activity
CF57_RS11255	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CF57_RS11260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CF57_RS11270	COG0477	Major facilitator Superfamily
CF57_RS11275	COG0246	Mannitol dehydrogenase
CF57_RS11285	COG1802	Transcriptional regulator
CF57_RS11290	COG4221	oxidoreductase activity
CF57_RS11295	COG0339	signal peptide processing
CF57_RS11300	COG1546	Belongs to the CinA family
CF57_RS11305	COG3111	PFAM Bacterial OB fold (BOF) protein
CF57_RS11310	COG3706	GGDEF domain
CF57_RS11320	COG2814	Major facilitator Superfamily
CF57_RS11325	COG0697	spore germination
CF57_RS11335	COG4977	sequence-specific DNA binding
CF57_RS11340	COG1846	Transcriptional regulator
CF57_RS11360	COG0583	DNA-binding transcription factor activity
CF57_RS11365	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS11370	COG2066	Belongs to the glutaminase family
CF57_RS11380	COG2199	diguanylate cyclase activity
CF57_RS11390	COG3781	membrane
CF57_RS11440	COG0840	transmembrane signaling receptor activity
CF57_RS11470	COG0697	spore germination
CF57_RS11485	COG3210	domain, Protein
CF57_RS11485	COG2911	Protein conserved in bacteria
CF57_RS11490	COG1396	sequence-specific DNA binding
CF57_RS11495	COG3550	peptidyl-serine autophosphorylation
CF57_RS11500	COG4977	sequence-specific DNA binding
CF57_RS11505	COG3188	usher protein
CF57_RS11510	COG3539	Fimbrial protein
CF57_RS11515	COG3539	Fimbrial protein
CF57_RS11520	COG3539	Fimbrial protein
CF57_RS11525	COG0243	molybdopterin cofactor binding
CF57_RS11530	COG3119	arylsulfatase activity
CF57_RS11535	COG0641	radical SAM
CF57_RS11540	COG4178	(ABC) transporter
CF57_RS11545	COG4771	TonB-dependent receptor
CF57_RS11550	COG0612	Peptidase, M16
CF57_RS11560	COG0076	glutamate decarboxylase activity
CF57_RS11565	COG0531	amino acid
CF57_RS11570	COG1649	PFAM Uncharacterised BCR, COG1649
CF57_RS11575	COG3706	GGDEF domain
CF57_RS11580	COG2202	Pas domain
CF57_RS11580	COG2199	diguanylate cyclase activity
CF57_RS11580	COG2200	EAL domain
CF57_RS11585	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CF57_RS11590	COG0747	negative chemotaxis
CF57_RS11595	COG0601	transmembrane transport
CF57_RS11600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF57_RS11605	COG0444	Belongs to the ABC transporter superfamily
CF57_RS11610	COG4608	Belongs to the ABC transporter superfamily
CF57_RS11615	COG1764	response to oxidative stress
CF57_RS11635	COG1064	alcohol dehydrogenase
CF57_RS11640	COG3093	addiction module antidote protein HigA
CF57_RS11645	COG2864	formate dehydrogenase
CF57_RS11650	COG0437	4 iron, 4 sulfur cluster binding
CF57_RS11655	COG0243	molybdopterin cofactor binding
CF57_RS11655	COG3383	formate dehydrogenase (NAD+) activity
CF57_RS11660	COG0243	molybdopterin cofactor binding
CF57_RS11660	COG3383	formate dehydrogenase (NAD+) activity
CF57_RS11665	COG0697	spore germination
CF57_RS11670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF57_RS11680	COG2223	nitrite transmembrane transporter activity
CF57_RS11685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CF57_RS11690	COG1140	nitrate reductase beta subunit
CF57_RS11695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CF57_RS11700	COG2181	nitrate reductase activity
CF57_RS11705	COG0384	phenazine biosynthesis protein PhzF
CF57_RS11710	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CF57_RS11715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CF57_RS11730	COG5433	transposase activity
CF57_RS11760	COG0625	glutathione transferase activity
CF57_RS11765	COG1113	amino acid transport
CF57_RS11770	COG3391	amine dehydrogenase activity
CF57_RS11775	COG4772	TonB-dependent receptor
CF57_RS11780	COG1802	Transcriptional regulator
CF57_RS11785	COG2130	NADP-dependent
CF57_RS11790	COG1247	-acetyltransferase
CF57_RS11795	COG3238	Protein conserved in bacteria
CF57_RS11820	COG1177	transmembrane transport
CF57_RS11825	COG1176	ABC-type spermidine putrescine transport system, permease component I
CF57_RS11830	COG3842	ATPase activity
CF57_RS11835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CF57_RS11840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CF57_RS11845	COG1598	PFAM Uncharacterised protein family UPF0150
CF57_RS11865	COG1396	sequence-specific DNA binding
CF57_RS11870	COG3135	benzoate transporter
CF57_RS11875	COG0675	Transposase, IS605 OrfB family
CF57_RS11895	COG0500	methyltransferase
CF57_RS11900	COG1275	C4-dicarboxylate transporter malic acid transport protein
CF57_RS11905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CF57_RS11910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF57_RS11915	COG2841	Protein conserved in bacteria
CF57_RS11930	COG5383	Protein conserved in bacteria
CF57_RS11935	COG0583	DNA-binding transcription factor activity
CF57_RS11940	COG0840	transmembrane signaling receptor activity
CF57_RS11945	COG2963	transposase activity
CF57_RS11950	COG2801	Transposase and inactivated derivatives
CF57_RS11965	COG3038	cytochrome b561
CF57_RS11970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CF57_RS11975	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS11980	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CF57_RS11985	COG1643	Atp-dependent helicase
CF57_RS11995	COG2453	phosphatase
CF57_RS11995	COG0671	phosphoesterase, PA-phosphatase related
CF57_RS12000	COG2267	carboxylic ester hydrolase activity
CF57_RS12005	COG4589	Belongs to the CDS family
CF57_RS12010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CF57_RS12030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CF57_RS12035	COG3327	negative regulation of DNA-templated transcription, initiation
CF57_RS12040	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CF57_RS12045	COG0183	Belongs to the thiolase family
CF57_RS12050	COG2050	protein possibly involved in aromatic compounds catabolism
CF57_RS12055	COG1250	3-hydroxyacyl-CoA dehydrogenase
CF57_RS12060	COG1024	Enoyl-CoA hydratase
CF57_RS12065	COG1024	Enoyl-CoA hydratase
CF57_RS12070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF57_RS12075	COG2151	metal-sulfur cluster biosynthetic enzyme
CF57_RS12080	COG3396	Phenylacetate-CoA oxygenase
CF57_RS12085	COG3460	Phenylacetate-CoA oxygenase
CF57_RS12090	COG3396	Phenylacetate-CoA oxygenase
CF57_RS12095	COG2030	dehydratase
CF57_RS12095	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS12100	COG3733	amine oxidase
CF57_RS12105	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS12110	COG2207	Transcriptional regulator
CF57_RS12115	COG3784	Protein of unknown function (DUF1318)
CF57_RS12125	COG2911	Protein conserved in bacteria
CF57_RS12130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CF57_RS12135	COG3187	Heat shock protein
CF57_RS12140	COG3042	response to heat
CF57_RS12145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CF57_RS12145	COG1013	pyruvate-flavodoxin oxidoreductase activity
CF57_RS12145	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CF57_RS12145	COG0674	pyruvate-flavodoxin oxidoreductase activity
CF57_RS12150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF57_RS12155	COG0589	response to stress
CF57_RS12165	COG0513	Belongs to the DEAD box helicase family
CF57_RS12180	COG3706	GGDEF domain
CF57_RS12185	COG2840	Smr protein MutS2
CF57_RS12195	COG0583	DNA-binding transcription factor activity
CF57_RS12200	COG1473	amidohydrolase
CF57_RS12205	COG1473	amidohydrolase
CF57_RS12215	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CF57_RS12220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CF57_RS12225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF57_RS12230	COG0589	response to stress
CF57_RS12235	COG3182	Iron-regulated membrane protein
CF57_RS12240	COG0668	transmembrane transport
CF57_RS12245	COG4166	transmembrane transport
CF57_RS12255	COG0583	DNA-binding transcription factor activity
CF57_RS12260	COG1073	alpha beta
CF57_RS12265	COG0702	epimerase
CF57_RS12270	COG2866	Carboxypeptidase
CF57_RS12275	COG4948	Mandelate Racemase Muconate Lactonizing
CF57_RS12280	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CF57_RS12285	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CF57_RS12295	COG3106	COG3106 Predicted ATPase
CF57_RS12300	COG1609	Transcriptional regulator
CF57_RS12310	COG3842	ATPase activity
CF57_RS12315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF57_RS12320	COG1554	hydrolase, family 65, central catalytic
CF57_RS12325	COG0673	inositol 2-dehydrogenase activity
CF57_RS12335	COG1063	alcohol dehydrogenase
CF57_RS12340	COG0395	ABC-type sugar transport system, permease component
CF57_RS12345	COG1175	transmembrane transport
CF57_RS12350	COG1653	transport
CF57_RS12355	COG0366	Alpha amylase catalytic
CF57_RS12360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF57_RS12370	COG1983	PspC domain protein
CF57_RS12380	COG1842	Phage shock protein A
CF57_RS12385	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CF57_RS12390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CF57_RS12395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CF57_RS12400	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS12405	COG1396	sequence-specific DNA binding
CF57_RS12405	COG1917	Cupin 2, conserved barrel domain protein
CF57_RS12410	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CF57_RS12415	COG0174	glutamine synthetase
CF57_RS12420	COG0531	amino acid
CF57_RS12435	COG4166	transmembrane transport
CF57_RS12440	COG4168	peptide transport system, permease
CF57_RS12450	COG4172	Belongs to the ABC transporter superfamily
CF57_RS12455	COG4172	Belongs to the ABC transporter superfamily
CF57_RS12460	COG2852	Protein conserved in bacteria
CF57_RS12470	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CF57_RS12475	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CF57_RS12475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CF57_RS12490	COG5001	Diguanylate cyclase
CF57_RS12500	COG1349	DNA-binding transcription factor activity
CF57_RS12510	COG0023	Translation Initiation Factor
CF57_RS12520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CF57_RS12525	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CF57_RS12530	COG0671	phosphoesterase, PA-phosphatase related
CF57_RS12540	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CF57_RS12560	COG0598	Magnesium transport protein CorA
CF57_RS12570	COG3698	Phosphodiester glycosidase
CF57_RS12575	COG3677	Transposase
CF57_RS12575	COG1662	PFAM IS1 transposase
CF57_RS12580	COG1662	PFAM IS1 transposase
CF57_RS12595	COG0583	DNA-binding transcription factor activity
CF57_RS12600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CF57_RS12615	COG0616	signal peptide processing
CF57_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS12630	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CF57_RS12635	COG1187	pseudouridine synthase activity
CF57_RS12645	COG0009	L-threonylcarbamoyladenylate synthase
CF57_RS12650	COG0613	PHP domain protein
CF57_RS12655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CF57_RS12660	COG0512	Glutamine amidotransferase of anthranilate synthase
CF57_RS12660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CF57_RS12665	COG0135	phosphoribosylanthranilate isomerase activity
CF57_RS12665	COG0134	indole-3-glycerol-phosphate synthase activity
CF57_RS12680	COG3729	General stress protein
CF57_RS12685	COG3685	Protein conserved in bacteria
CF57_RS12690	COG3685	Protein conserved in bacteria
CF57_RS12695	COG3047	cAMP biosynthetic process
CF57_RS12710	COG1607	acyl-coa hydrolase
CF57_RS12715	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CF57_RS12720	COG2350	Protein conserved in bacteria
CF57_RS12725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CF57_RS12745	COG4608	Belongs to the ABC transporter superfamily
CF57_RS12750	COG0444	Belongs to the ABC transporter superfamily
CF57_RS12755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF57_RS12760	COG0601	transmembrane transport
CF57_RS12765	COG4166	transmembrane transport
CF57_RS12770	COG2095	MarC family integral membrane protein
CF57_RS12775	COG1454	alcohol dehydrogenase
CF57_RS12775	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS12780	COG1435	thymidine kinase activity
CF57_RS12790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CF57_RS12795	COG0745	RESPONSE REGULATOR receiver
CF57_RS12800	COG1752	Esterase of the alpha-beta hydrolase superfamily
CF57_RS12810	COG0788	formyltetrahydrofolate deformylase activity
CF57_RS12830	COG2181	nitrate reductase activity
CF57_RS12835	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CF57_RS12840	COG1140	nitrate reductase beta subunit
CF57_RS12845	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CF57_RS12850	COG2223	nitrite transmembrane transporter activity
CF57_RS12860	COG3850	Histidine kinase
CF57_RS12865	COG2197	response regulator
CF57_RS12870	COG4932	domain protein
CF57_RS12875	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CF57_RS12880	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CF57_RS12885	COG4572	Cation transport regulator
CF57_RS12890	COG0387	Pfam Sodium calcium exchanger
CF57_RS12905	COG2963	transposase activity
CF57_RS12910	COG2801	Transposase and inactivated derivatives
CF57_RS12925	COG2912	Transglutaminase-like superfamily
CF57_RS12930	COG3094	Invasion gene expression up-regulator, SirB
CF57_RS12935	COG2890	protein-(glutamine-N5) methyltransferase activity
CF57_RS12960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CF57_RS12965	COG0659	secondary active sulfate transmembrane transporter activity
CF57_RS12980	COG0012	GTP binding
CF57_RS12990	COG3468	outer membrane autotransporter barrel domain protein
CF57_RS12995	COG3284	Transcriptional regulator
CF57_RS13000	COG2376	Dihydroxyacetone kinase
CF57_RS13005	COG1461	Dihydroxyacetone kinase
CF57_RS13010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF57_RS13010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS13010	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CF57_RS13030	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CF57_RS13040	COG1619	proteins homologs of microcin C7 resistance protein MccF
CF57_RS13050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CF57_RS13060	COG2719	SpoVR family
CF57_RS13075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CF57_RS13080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CF57_RS13085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CF57_RS13100	COG0179	Fumarylacetoacetate (FAA) hydrolase
CF57_RS13130	COG2894	cell division
CF57_RS13185	COG2200	EAL domain
CF57_RS13210	COG2200	EAL domain
CF57_RS13215	COG0789	Transcriptional regulator
CF57_RS13220	COG5562	phage envelope protein
CF57_RS13235	COG0538	isocitrate dehydrogenase activity
CF57_RS13240	COG1187	pseudouridine synthase activity
CF57_RS13260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CF57_RS13265	COG0745	RESPONSE REGULATOR receiver
CF57_RS13270	COG2205	protein histidine kinase activity
CF57_RS13275	COG2850	peptidyl-arginine hydroxylation
CF57_RS13300	COG1177	transmembrane transport
CF57_RS13305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CF57_RS13315	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CF57_RS13320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CF57_RS13330	COG4591	ABC-type transport system involved in lipoprotein release permease component
CF57_RS13335	COG1136	(ABC) transporter
CF57_RS13340	COG4591	ABC-type transport system involved in lipoprotein release permease component
CF57_RS13350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CF57_RS13355	COG1376	ErfK ybiS ycfS ynhG family protein
CF57_RS13355	COG1388	LysM domain
CF57_RS13365	COG1309	transcriptional regulator
CF57_RS13370	COG3134	Outer membrane lipoprotein
CF57_RS13375	COG1252	NADH dehydrogenase
CF57_RS13395	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CF57_RS13400	COG5633	Lipoprotein
CF57_RS13405	COG0537	adenosine 5'-monophosphoramidase activity
CF57_RS13410	COG4773	Receptor
CF57_RS13415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS13415	COG1263	PTS System
CF57_RS13420	COG0084	hydrolase, TatD family'
CF57_RS13425	COG0470	DNA polymerase III
CF57_RS13435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CF57_RS13440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CF57_RS13445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CF57_RS13455	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS13460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CF57_RS13480	COG1399	metal-binding, possibly nucleic acid-binding protein
CF57_RS13485	COG0424	maF-like protein
CF57_RS13490	COG0564	pseudouridine synthase activity
CF57_RS13500	COG1530	ribonuclease E activity
CF57_RS13505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CF57_RS13510	COG1256	bacterial-type flagellum assembly
CF57_RS13515	COG1705	Flagellar rod assembly protein muramidase FlgJ
CF57_RS13515	COG3951	Flagellar rod assembly protein muramidase FlgJ
CF57_RS13530	COG4786	Flagellar basal body rod
CF57_RS13535	COG4787	bacterial-type flagellum-dependent cell motility
CF57_RS13540	COG1749	Flagellar hook protein flgE
CF57_RS13545	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CF57_RS13550	COG1558	bacterial-type flagellum-dependent cell motility
CF57_RS13555	COG1815	bacterial-type flagellum-dependent cell motility
CF57_RS13560	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CF57_RS13565	COG2747	anti-sigma28 factor FlgM
CF57_RS13570	COG3418	PFAM FlgN family protein
CF57_RS13575	COG0728	peptidoglycan biosynthetic process
CF57_RS13580	COG0673	inositol 2-dehydrogenase activity
CF57_RS13590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF57_RS13600	COG2999	glutathione oxidoreductase activity
CF57_RS13635	COG3038	cytochrome b561
CF57_RS13640	COG2353	YceI-like domain
CF57_RS13650	COG1560	Kdo2-lipid A biosynthetic process
CF57_RS13670	COG5645	(Lipo)protein
CF57_RS13675	COG2943	transferase activity, transferring hexosyl groups
CF57_RS13700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CF57_RS13705	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CF57_RS13710	COG1662	PFAM IS1 transposase
CF57_RS13740	COG2197	response regulator
CF57_RS13755	COG1462	curli production assembly transport component CsgG
CF57_RS13765	COG3381	protein complex oligomerization
CF57_RS13805	COG2801	Transposase and inactivated derivatives
CF57_RS13820	COG1649	PFAM Uncharacterised BCR, COG1649
CF57_RS13820	COG0726	polysaccharide deacetylase
CF57_RS13825	COG1215	transferase activity, transferring glycosyl groups
CF57_RS13830	COG3658	cytochrome
CF57_RS13835	COG1702	phosphate starvation-inducible protein PhoH
CF57_RS13845	COG2837	iron assimilation
CF57_RS13850	COG2822	iron ion transport
CF57_RS13865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CF57_RS13875	COG0506	proline dehydrogenase activity
CF57_RS13875	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CF57_RS13875	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CF57_RS13880	COG1309	transcriptional regulator
CF57_RS13890	COG1335	isochorismatase
CF57_RS13915	COG2233	PERMEase
CF57_RS13920	COG3729	General stress protein
CF57_RS13965	COG0243	molybdopterin cofactor binding
CF57_RS13970	COG3005	denitrification pathway
CF57_RS13975	COG0745	RESPONSE REGULATOR receiver
CF57_RS13980	COG1879	ABC-type sugar transport system periplasmic component
CF57_RS13985	COG2198	Histidine kinase
CF57_RS13985	COG0784	Response regulator, receiver
CF57_RS13985	COG2205	protein histidine kinase activity
CF57_RS13990	COG0348	domain, Protein
CF57_RS14005	COG1278	Cold shock
CF57_RS14010	COG1278	Cold shock
CF57_RS14035	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF57_RS14040	COG1596	polysaccharide export
CF57_RS14045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CF57_RS14050	COG0489	protein tyrosine kinase activity
CF57_RS14050	COG3206	protein involved in exopolysaccharide biosynthesis
CF57_RS14065	COG1294	oxidase, subunit
CF57_RS14070	COG1271	oxidase subunit
CF57_RS14075	COG1773	rubredoxin
CF57_RS14080	COG1999	signal sequence binding
CF57_RS14085	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CF57_RS14090	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CF57_RS14095	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CF57_RS14100	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CF57_RS14110	COG0670	Belongs to the BI1 family
CF57_RS14115	COG2920	part of a sulfur-relay system
CF57_RS14120	COG1254	Belongs to the acylphosphatase family
CF57_RS14135	COG1832	CoA-binding protein
CF57_RS14155	COG0210	DNA helicase
CF57_RS14160	COG3304	Inner membrane component domain
CF57_RS14165	COG1289	transmembrane transporter activity
CF57_RS14170	COG3070	regulator of competence-specific genes
CF57_RS14185	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CF57_RS14185	COG2885	chlorophyll binding
CF57_RS14195	COG1067	ATP-dependent peptidase activity
CF57_RS14205	COG3130	regulation of translation
CF57_RS14210	COG3009	Protein conserved in bacteria
CF57_RS14215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CF57_RS14215	COG3008	intermembrane lipid transfer
CF57_RS14220	COG2995	paraquat-inducible protein a
CF57_RS14225	COG0488	(ABC) transporter
CF57_RS14235	COG0633	Ferredoxin
CF57_RS14235	COG3217	Mosc domain protein beta barrel domain protein
CF57_RS14250	COG3121	Chaperone
CF57_RS14255	COG3539	Fimbrial protein
CF57_RS14260	COG3539	Fimbrial protein
CF57_RS14265	COG3539	Fimbrial protein
CF57_RS14270	COG3188	usher protein
CF57_RS14275	COG3121	Chaperone
CF57_RS14280	COG3539	Fimbrial protein
CF57_RS14285	COG0431	NADPH-dependent FMN reductase
CF57_RS14290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CF57_RS14300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CF57_RS14305	COG1116	anion transmembrane transporter activity
CF57_RS14310	COG0308	aminopeptidase N
CF57_RS14335	COG1448	Aminotransferase
CF57_RS14340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CF57_RS14345	COG3108	Peptidase M15
CF57_RS14350	COG2989	Protein conserved in bacteria
CF57_RS14360	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CF57_RS14370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CF57_RS14375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CF57_RS14380	COG3173	Aminoglycoside phosphotransferase
CF57_RS14395	COG3214	Protein conserved in bacteria
CF57_RS14405	COG1132	(ABC) transporter
CF57_RS14410	COG2333	competence protein COMEC
CF57_RS14410	COG0658	competence protein
CF57_RS14420	COG0539	negative regulation of cytoplasmic translation
CF57_RS14430	COG0501	Belongs to the peptidase M48B family
CF57_RS14445	COG2323	membrane
CF57_RS14450	COG1944	ATP diphosphatase activity
CF57_RS14455	COG2116	formate transmembrane transporter activity
CF57_RS14460	COG1882	Formate acetyltransferase
CF57_RS14465	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CF57_RS14470	COG2249	NAD(P)H dehydrogenase (quinone) activity
CF57_RS14475	COG0583	DNA-binding transcription factor activity
CF57_RS14480	COG0531	amino acid
CF57_RS14490	COG1335	isochorismatase
CF57_RS14495	COG3302	dmso reductase anchor subunit
CF57_RS14500	COG0437	4 iron, 4 sulfur cluster binding
CF57_RS14505	COG0243	molybdopterin cofactor binding
CF57_RS14515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CF57_RS14525	COG1178	ABC-type Fe3 transport system permease component
CF57_RS14525	COG1674	ftsk spoiiie
CF57_RS14530	COG1522	sequence-specific DNA binding
CF57_RS14535	COG0492	ferredoxin-NADP+ reductase activity
CF57_RS14540	COG4988	ABC transporter
CF57_RS14545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CF57_RS14565	COG0542	response to heat
CF57_RS14575	COG1278	Cold shock
CF57_RS14580	COG1136	(ABC) transporter
CF57_RS14580	COG0577	efflux transmembrane transporter activity
CF57_RS14585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF57_RS14590	COG2990	Protein conserved in bacteria
CF57_RS14595	COG3593	DNA synthesis involved in DNA repair
CF57_RS14610	COG2431	L-lysine efflux transmembrane transporter activity
CF57_RS14620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF57_RS14625	COG0028	Belongs to the TPP enzyme family
CF57_RS14630	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CF57_RS14635	COG0702	epimerase
CF57_RS14640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF57_RS14645	COG3023	N-Acetylmuramoyl-L-alanine amidase
CF57_RS14660	COG1126	abc transporter atp-binding protein
CF57_RS14665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF57_RS14670	COG4215	(ABC) transporter
CF57_RS14675	COG4160	amino acid transport
CF57_RS14680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF57_RS14695	COG1177	transmembrane transport
CF57_RS14700	COG1176	ABC-type spermidine putrescine transport system, permease component I
CF57_RS14705	COG3842	ATPase activity
CF57_RS14710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CF57_RS14730	COG1662	PFAM IS1 transposase
CF57_RS14735	COG0778	Nitroreductase
CF57_RS14745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CF57_RS14760	COG3226	Transcriptional regulator
CF57_RS14765	COG0738	Major facilitator superfamily
CF57_RS14770	COG0561	phosphatase activity
CF57_RS14780	COG2814	Major facilitator Superfamily
CF57_RS14785	COG0671	phosphoesterase, PA-phosphatase related
CF57_RS14790	COG1349	DNA-binding transcription factor activity
CF57_RS14795	COG1686	Belongs to the peptidase S11 family
CF57_RS14800	COG0625	glutathione transferase activity
CF57_RS14820	COG2199	diguanylate cyclase activity
CF57_RS14825	COG2200	EAL domain
CF57_RS14840	COG0747	negative chemotaxis
CF57_RS14850	COG1446	asparaginase
CF57_RS14855	COG0303	'Molybdopterin
CF57_RS14860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CF57_RS14865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CF57_RS14870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CF57_RS14875	COG1882	Formate acetyltransferase
CF57_RS14880	COG0561	phosphatase activity
CF57_RS14890	COG0488	(ABC) transporter
CF57_RS14895	COG1376	ErfK ybiS ycfS ynhG family protein
CF57_RS14900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CF57_RS14905	COG1321	iron dependent repressor
CF57_RS14915	COG2194	sulfuric ester hydrolase activity
CF57_RS14920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CF57_RS14925	COG5006	permease, DMT superfamily
CF57_RS14940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF57_RS14945	COG0765	amino acid transport
CF57_RS14950	COG1126	abc transporter atp-binding protein
CF57_RS14955	COG0668	transmembrane transport
CF57_RS14970	COG4774	siderophore transport
CF57_RS14980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CF57_RS14990	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CF57_RS14995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CF57_RS15000	COG1199	ATP-dependent helicase activity
CF57_RS15005	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CF57_RS15010	COG0513	Belongs to the DEAD box helicase family
CF57_RS15015	COG1309	transcriptional regulator
CF57_RS15025	COG1131	(ABC) transporter
CF57_RS15030	COG0842	Transport permease protein
CF57_RS15035	COG0842	Transport permease protein
CF57_RS15045	COG3568	Endonuclease Exonuclease Phosphatase
CF57_RS15050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CF57_RS15055	COG0392	lysyltransferase activity
CF57_RS15060	COG0670	Belongs to the BI1 family
CF57_RS15065	COG0670	Belongs to the BI1 family
CF57_RS15070	COG0314	molybdopterin synthase activity
CF57_RS15075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CF57_RS15085	COG0521	Mo-molybdopterin cofactor biosynthetic process
CF57_RS15100	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CF57_RS15110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CF57_RS15115	COG2226	methyltransferase
CF57_RS15130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CF57_RS15135	COG1881	PFAM PEBP family protein
CF57_RS15250	COG0494	nUDIX hydrolase
CF57_RS15340	COG0305	Participates in initiation and elongation during chromosome replication
CF57_RS15410	COG4712	double-strand break repair protein
CF57_RS15470	COG0582	viral genome integration into host DNA
CF57_RS15475	COG4677	pectinesterase activity
CF57_RS15480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CF57_RS15485	COG0471	metal ion transport
CF57_RS15490	COG2828	Protein conserved in bacteria
CF57_RS15495	COG0583	DNA-binding transcription factor activity
CF57_RS15505	COG0561	phosphatase activity
CF57_RS15510	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CF57_RS15515	COG4149	molybdate abc transporter
CF57_RS15520	COG0725	ABC transporter, periplasmic molybdate-binding protein
CF57_RS15530	COG2005	Transcriptional regulator
CF57_RS15530	COG3585	molybdate ion transport
CF57_RS15540	COG1119	ATPase activity
CF57_RS15545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CF57_RS15550	COG1085	galactose-1-phosphate uridylyltransferase
CF57_RS15560	COG2017	converts alpha-aldose to the beta-anomer
CF57_RS15570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CF57_RS15585	COG1230	cation diffusion facilitator family transporter
CF57_RS15590	COG3201	nicotinamide mononucleotide transporter
CF57_RS15635	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CF57_RS15640	COG2885	chlorophyll binding
CF57_RS15650	COG3064	Membrane
CF57_RS15655	COG0848	biopolymer transport protein
CF57_RS15660	COG0811	peptide transport
CF57_RS15665	COG0824	Thioesterase
CF57_RS15670	COG3790	cyd operon protein YbgE
CF57_RS15675	COG4890	Cyd operon protein YbgT
CF57_RS15680	COG1294	oxidase, subunit
CF57_RS15685	COG1271	oxidase subunit
CF57_RS15695	COG0383	alpha-mannosidase activity
CF57_RS15700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS15700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS15700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS15705	COG2188	Transcriptional regulator
CF57_RS15710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CF57_RS15720	COG0508	dehydrogenase complex catalyzes the overall conversion of
CF57_RS15725	COG0567	Dehydrogenase, E1 component
CF57_RS15735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CF57_RS15740	COG1053	succinate dehydrogenase
CF57_RS15745	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CF57_RS15750	COG2009	succinate dehydrogenase
CF57_RS15760	COG0372	Belongs to the citrate synthase family
CF57_RS15765	COG3539	Fimbrial protein
CF57_RS15770	COG3188	usher protein
CF57_RS15775	COG3121	Chaperone
CF57_RS15780	COG3539	Fimbrial protein
CF57_RS15785	COG3180	Ammonia monooxygenase
CF57_RS15800	COG1984	allophanate hydrolase subunit 2
CF57_RS15805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CF57_RS15810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CF57_RS15815	COG3104	oligopeptide transport
CF57_RS15820	COG0415	Belongs to the DNA photolyase family
CF57_RS15825	COG3272	Protein of unknown function (DUF1722)
CF57_RS15830	COG5433	transposase activity
CF57_RS15840	COG5433	transposase activity
CF57_RS15850	COG3209	COG3209 Rhs family protein
CF57_RS15880	COG2205	protein histidine kinase activity
CF57_RS15885	COG0745	RESPONSE REGULATOR receiver
CF57_RS15895	COG1982	Orn Lys Arg decarboxylase major
CF57_RS15900	COG0531	amino acid
CF57_RS15920	COG0033	Phosphoglucomutase
CF57_RS15925	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CF57_RS15930	COG0596	Alpha beta hydrolase
CF57_RS15940	COG0716	FMN binding
CF57_RS15955	COG0735	belongs to the Fur family
CF57_RS15975	COG2190	(PTS) system
CF57_RS15975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS15975	COG1263	PTS System
CF57_RS15985	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CF57_RS15990	COG1940	carbohydrate kinase activity
CF57_RS15990	COG1846	Transcriptional regulator
CF57_RS15995	COG0647	UMP catabolic process
CF57_RS16000	COG0367	asparagine synthase
CF57_RS16040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CF57_RS16050	COG1702	phosphate starvation-inducible protein PhoH
CF57_RS16060	COG4535	Mg2 and Co2 transporter CorC
CF57_RS16065	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CF57_RS16075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF57_RS16080	COG0765	amino acid transport
CF57_RS16085	COG0765	amino acid transport
CF57_RS16090	COG1126	abc transporter atp-binding protein
CF57_RS16100	COG0443	Heat shock 70 kDa protein
CF57_RS16105	COG2214	Heat shock protein DnaJ domain protein
CF57_RS16115	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CF57_RS16120	COG2214	Heat shock protein DnaJ domain protein
CF57_RS16130	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CF57_RS16135	COG2888	peptidyl-tyrosine sulfation
CF57_RS16150	COG1466	dna polymerase III delta subunit
CF57_RS16160	COG0406	alpha-ribazole phosphatase activity
CF57_RS16165	COG0799	negative regulation of ribosome biogenesis
CF57_RS16175	COG0768	penicillin binding
CF57_RS16180	COG0772	Belongs to the SEDS family
CF57_RS16185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CF57_RS16190	COG1686	Belongs to the peptidase S11 family
CF57_RS16210	COG0583	DNA-binding transcription factor activity
CF57_RS16220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CF57_RS16225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CF57_RS16245	COG3069	C4-dicarboxylate transmembrane transporter activity
CF57_RS16250	COG4565	transcriptional regulatory protein
CF57_RS16255	COG3290	protein histidine kinase activity
CF57_RS16260	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CF57_RS16270	COG2301	Belongs to the HpcH HpaI aldolase family
CF57_RS16275	COG3051	citrate lyase alpha subunit
CF57_RS16290	COG0471	metal ion transport
CF57_RS16295	COG3719	Belongs to the RNase T2 family
CF57_RS16300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CF57_RS16310	COG1063	alcohol dehydrogenase
CF57_RS16315	COG0589	response to stress
CF57_RS16320	COG3634	alkyl hydroperoxide reductase activity
CF57_RS16325	COG0450	alkyl hydroperoxide reductase
CF57_RS16330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CF57_RS16335	COG0583	DNA-binding transcription factor activity
CF57_RS16340	COG3969	phosphoadenosine phosphosulfate
CF57_RS16345	COG1475	DNA binding
CF57_RS16350	COG0436	Aminotransferase
CF57_RS16355	COG0371	Dehydrogenase
CF57_RS16360	COG2879	small protein
CF57_RS16365	COG1966	Carbon starvation protein
CF57_RS16370	COG2050	protein possibly involved in aromatic compounds catabolism
CF57_RS16375	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS16380	COG1535	isochorismatase
CF57_RS16380	COG3433	isochorismatase activity
CF57_RS16385	COG1021	2,3-dihydroxybenzoate-AMP ligase
CF57_RS16390	COG1169	isochorismate synthase
CF57_RS16395	COG4592	Periplasmic binding protein
CF57_RS16405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF57_RS16410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF57_RS16415	COG1120	ATPase activity
CF57_RS16420	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CF57_RS16425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF57_RS16425	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CF57_RS16430	COG3251	PFAM MbtH domain protein
CF57_RS16435	COG2382	esterase
CF57_RS16440	COG4771	TonB-dependent receptor
CF57_RS16445	COG2977	Belongs to the P-Pant transferase superfamily
CF57_RS16450	COG3385	transposase activity
CF57_RS16475	COG2315	Protein conserved in bacteria
CF57_RS16480	COG0778	Nitroreductase
CF57_RS16485	COG1662	PFAM IS1 transposase
CF57_RS16490	COG0668	transmembrane transport
CF57_RS16495	COG1113	amino acid transport
CF57_RS16500	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF57_RS16505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF57_RS16510	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF57_RS16515	COG1538	Outer membrane efflux protein
CF57_RS16520	COG0745	RESPONSE REGULATOR receiver
CF57_RS16525	COG5002	protein histidine kinase activity
CF57_RS16540	COG4104	PAAR repeat-containing protein
CF57_RS16540	COG3209	COG3209 Rhs family protein
CF57_RS16560	COG5433	transposase activity
CF57_RS16570	COG4783	chaperone-mediated protein folding
CF57_RS16580	COG2207	Transcriptional regulator
CF57_RS16590	COG2197	response regulator
CF57_RS16595	COG3539	Fimbrial protein
CF57_RS16600	COG3539	Fimbrial protein
CF57_RS16605	COG3188	usher protein
CF57_RS16610	COG3121	Chaperone
CF57_RS16615	COG3539	Fimbrial protein
CF57_RS16625	COG2501	S4 domain
CF57_RS16630	COG1988	membrane-bound metal-dependent
CF57_RS16640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CF57_RS16650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CF57_RS16655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CF57_RS16660	COG0549	Belongs to the carbamate kinase family
CF57_RS16670	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CF57_RS16675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CF57_RS16680	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CF57_RS16685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CF57_RS16690	COG3257	ureidoglycine aminohydrolase activity
CF57_RS16695	COG1929	Belongs to the glycerate kinase type-1 family
CF57_RS16700	COG2233	PERMEase
CF57_RS16710	COG1953	Uracil, thiamine, allantoin
CF57_RS16715	COG2084	Dehydrogenase
CF57_RS16720	COG3622	Belongs to the hyi family
CF57_RS16725	COG3960	tartronate-semialdehyde synthase activity
CF57_RS16730	COG1414	Transcriptional regulator
CF57_RS16740	COG0583	DNA-binding transcription factor activity
CF57_RS16750	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CF57_RS16755	COG4181	ATPase activity
CF57_RS16760	COG2755	lipolytic protein G-D-S-L family
CF57_RS16765	COG0300	oxidoreductase activity
CF57_RS16770	COG3118	belongs to the thioredoxin family
CF57_RS16775	COG0390	transport system, permease component
CF57_RS16780	COG4619	ABC transporter
CF57_RS16785	COG0330	HflC and HflK could
CF57_RS16790	COG1585	Membrane protein implicated in regulation of membrane protease activity
CF57_RS16795	COG0789	Transcriptional regulator
CF57_RS16800	COG0531	amino acid
CF57_RS16810	COG2217	Heavy metal translocating P-type atpase
CF57_RS16815	COG3093	addiction module antidote protein HigA
CF57_RS16820	COG3735	TraB family
CF57_RS16825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CF57_RS16830	COG0737	Belongs to the 5'-nucleotidase family
CF57_RS16835	COG2223	nitrite transmembrane transporter activity
CF57_RS16840	COG4651	solute:proton antiporter activity
CF57_RS16840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CF57_RS16845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF57_RS16880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CF57_RS16890	COG2832	Protein of unknown function (DUF454)
CF57_RS16895	COG3923	Primosomal replication protein n
CF57_RS16910	COG3264	Mechanosensitive ion channel
CF57_RS16910	COG1196	nuclear chromosome segregation
CF57_RS16915	COG1309	transcriptional regulator
CF57_RS16920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF57_RS16925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF57_RS16940	COG0110	maltose O-acetyltransferase activity
CF57_RS16950	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CF57_RS16955	COG5507	3-demethylubiquinone-9 3-methyltransferase
CF57_RS16960	COG3695	enzyme binding
CF57_RS16965	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CF57_RS16970	COG1946	Acyl-CoA thioesterase
CF57_RS16975	COG0004	ammonium transporteR
CF57_RS16980	COG0347	Belongs to the P(II) protein family
CF57_RS16985	COG1132	(ABC) transporter
CF57_RS16990	COG1132	(ABC) transporter
CF57_RS16995	COG1522	sequence-specific DNA binding
CF57_RS17005	COG4533	DNA binding
CF57_RS17015	COG0824	Thioesterase
CF57_RS17020	COG1555	photosystem II stabilization
CF57_RS17025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CF57_RS17030	COG0776	regulation of translation
CF57_RS17035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CF57_RS17060	COG0271	Belongs to the BolA IbaG family
CF57_RS17065	COG3056	Lipoprotein
CF57_RS17070	COG2223	nitrite transmembrane transporter activity
CF57_RS17075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CF57_RS17080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CF57_RS17085	COG1845	cytochrome c oxidase, subunit III
CF57_RS17090	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CF57_RS17100	COG2814	Major facilitator Superfamily
CF57_RS17110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CF57_RS17115	COG0693	protein deglycase activity
CF57_RS17130	COG0142	geranyltranstransferase activity
CF57_RS17140	COG0667	Aldo Keto reductase
CF57_RS17145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CF57_RS17150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CF57_RS17165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CF57_RS17165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CF57_RS17175	COG4238	major outer membrane lipoprotein
CF57_RS17180	COG3248	Nucleoside-binding outer membrane protein
CF57_RS17190	COG1403	HNH endonuclease
CF57_RS17195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CF57_RS17200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CF57_RS17205	COG1862	Preprotein translocase
CF57_RS17225	COG0366	Alpha amylase catalytic
CF57_RS17230	COG1113	amino acid transport
CF57_RS17235	COG1114	Component of the transport system for branched-chain amino acids
CF57_RS17240	COG5002	protein histidine kinase activity
CF57_RS17245	COG0745	RESPONSE REGULATOR receiver
CF57_RS17250	COG0420	3'-5' exonuclease activity
CF57_RS17255	COG0419	ATPase involved in DNA repair
CF57_RS17260	COG2814	Major facilitator Superfamily
CF57_RS17265	COG1940	carbohydrate kinase activity
CF57_RS17285	COG4126	flavin adenine dinucleotide binding
CF57_RS17310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CF57_RS17315	COG3706	GGDEF domain
CF57_RS17325	COG1785	Belongs to the alkaline phosphatase family
CF57_RS17340	COG1181	Belongs to the D-alanine--D-alanine ligase family
CF57_RS17360	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CF57_RS17370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF57_RS17375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF57_RS17380	COG3468	outer membrane autotransporter barrel domain protein
CF57_RS17385	COG0113	porphobilinogen synthase activity
CF57_RS17390	COG2175	clavaminate synthase activity
CF57_RS17395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CF57_RS17405	COG4521	taurine ABC transporter
CF57_RS17410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CF57_RS17415	COG1215	transferase activity, transferring glycosyl groups
CF57_RS17445	COG3122	Protein conserved in bacteria
CF57_RS17450	COG2814	Major facilitator Superfamily
CF57_RS17465	COG3971	2-oxopent-4-enoate hydratase activity
CF57_RS17485	COG1414	Transcriptional regulator
CF57_RS17490	COG1609	Transcriptional regulator
CF57_RS17495	COG3250	beta-galactosidase activity
CF57_RS17500	COG2223	nitrite transmembrane transporter activity
CF57_RS17505	COG0110	maltose O-acetyltransferase activity
CF57_RS17510	COG2807	transmembrane transport
CF57_RS17520	COG0288	reversible hydration of carbon dioxide
CF57_RS17525	COG0583	DNA-binding transcription factor activity
CF57_RS17530	COG0402	S-adenosylhomocysteine deaminase activity
CF57_RS17535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CF57_RS17540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CF57_RS17545	COG2079	MmgE PrpD family protein
CF57_RS17550	COG0372	Belongs to the citrate synthase family
CF57_RS17555	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CF57_RS17560	COG3829	transcription factor binding
CF57_RS17570	COG1280	lysine exporter protein (LysE YggA)
CF57_RS17585	COG1064	alcohol dehydrogenase
CF57_RS17590	COG0402	S-adenosylhomocysteine deaminase activity
CF57_RS17595	COG0549	Belongs to the carbamate kinase family
CF57_RS17605	COG1304	FMN binding
CF57_RS17610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CF57_RS17620	COG0666	response to abiotic stimulus
CF57_RS17630	COG0583	DNA-binding transcription factor activity
CF57_RS17635	COG2200	EAL domain
CF57_RS17635	COG2771	luxR family
CF57_RS17645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CF57_RS17675	COG1556	Lactate utilization protein
CF57_RS17680	COG1139	Iron-sulfur cluster binding protein
CF57_RS17685	COG0247	lactate metabolic process
CF57_RS17690	COG2207	Transcriptional regulator
CF57_RS17695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF57_RS17705	COG3059	membrane
CF57_RS17710	COG3708	Transcriptional regulator
CF57_RS17710	COG2207	Transcriptional regulator
CF57_RS17715	COG1388	LysM domain
CF57_RS17755	COG3188	usher protein
CF57_RS17765	COG3121	Chaperone
CF57_RS17770	COG0727	PFAM Uncharacterised protein family (UPF0153)
CF57_RS17775	COG3477	response to acidic pH
CF57_RS17780	COG2080	2 iron, 2 sulfur cluster binding
CF57_RS17785	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CF57_RS17790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CF57_RS17795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CF57_RS17800	COG0583	DNA-binding transcription factor activity
CF57_RS17840	COG4626	Terminase
CF57_RS17840	COG1802	Transcriptional regulator
CF57_RS17895	COG1403	HNH endonuclease
CF57_RS17920	COG1846	Transcriptional regulator
CF57_RS17960	COG5532	Uncharacterized conserved protein (DUF2303)
CF57_RS17965	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CF57_RS17980	COG0582	viral genome integration into host DNA
CF57_RS18000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF57_RS18020	COG2195	Cleaves the N-terminal amino acid of tripeptides
CF57_RS18025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CF57_RS18030	COG1690	Belongs to the RtcB family
CF57_RS18035	COG0454	-acetyltransferase
CF57_RS18045	COG2161	toxin-antitoxin pair type II binding
CF57_RS18060	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CF57_RS18065	COG1191	sigma factor activity
CF57_RS18090	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CF57_RS18095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CF57_RS18110	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CF57_RS18135	COG4786	Flagellar basal body rod
CF57_RS18140	COG4787	bacterial-type flagellum-dependent cell motility
CF57_RS18145	COG1749	Flagellar hook protein flgE
CF57_RS18155	COG1558	bacterial-type flagellum-dependent cell motility
CF57_RS18160	COG1815	bacterial-type flagellum-dependent cell motility
CF57_RS18190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CF57_RS18210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CF57_RS18220	COG1677	Flagellar hook-basal body complex protein FliE
CF57_RS18245	COG1987	bacterial-type flagellum assembly
CF57_RS18265	COG1943	Transposase
CF57_RS18270	COG0791	NLP P60 protein
CF57_RS18275	COG3034	peptidoglycan biosynthetic process
CF57_RS18280	COG0121	glutamine amidotransferase
CF57_RS18290	COG1960	acyl-CoA dehydrogenase activity
CF57_RS18300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CF57_RS18305	COG5433	transposase activity
CF57_RS18315	COG3209	COG3209 Rhs family protein
CF57_RS18330	COG3157	Type VI secretion system effector, Hcp
CF57_RS18335	COG4104	PAAR repeat-containing protein
CF57_RS18355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CF57_RS18365	COG2226	methyltransferase
CF57_RS18375	COG0741	lytic transglycosylase activity
CF57_RS18375	COG1388	LysM domain
CF57_RS18380	COG2226	methyltransferase
CF57_RS18390	COG0583	DNA-binding transcription factor activity
CF57_RS18395	COG0656	L-ascorbic acid biosynthetic process
CF57_RS18430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CF57_RS18435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CF57_RS18440	COG2011	ABC-type metal ion transport system permease component
CF57_RS18445	COG1464	Belongs to the NlpA lipoprotein family
CF57_RS18455	COG1720	tRNA m6t6A37 methyltransferase activity
CF57_RS18465	COG0791	NLP P60 protein
CF57_RS18470	COG3015	lipoprotein NlpE involved in copper resistance
CF57_RS18475	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CF57_RS18480	COG4681	YaeQ
CF57_RS18490	COG4568	rho-dependent transcription termination
CF57_RS18500	COG0346	lactoylglutathione lyase activity
CF57_RS18505	COG1982	Orn Lys Arg decarboxylase major
CF57_RS18515	COG0587	DNA-directed DNA polymerase activity
CF57_RS18540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CF57_RS18545	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CF57_RS18555	COG0750	zinc metalloprotease
CF57_RS18560	COG0575	Belongs to the CDS family
CF57_RS18565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CF57_RS18570	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CF57_RS18595	COG0024	Methionine aminopeptidase
CF57_RS18610	COG1408	metallophosphoesterase
CF57_RS18620	COG3835	regulator
CF57_RS18625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF57_RS18640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CF57_RS18645	COG2860	membrane
CF57_RS18665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF57_RS18670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CF57_RS18675	COG1120	ATPase activity
CF57_RS18680	COG4774	siderophore transport
CF57_RS18685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CF57_RS18695	COG1643	Atp-dependent helicase
CF57_RS18700	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CF57_RS18710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CF57_RS18720	COG0617	tRNA 3'-terminal CCA addition
CF57_RS18725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CF57_RS18730	COG1662	PFAM IS1 transposase
CF57_RS18735	COG3539	Fimbrial protein
CF57_RS18740	COG3539	Fimbrial protein
CF57_RS18765	COG5464	transposase or invertase
CF57_RS18775	COG0726	polysaccharide deacetylase
CF57_RS18780	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS18785	COG0842	Transport permease protein
CF57_RS18790	COG1131	(ABC) transporter
CF57_RS18795	COG0288	reversible hydration of carbon dioxide
CF57_RS18800	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CF57_RS18805	COG4993	Dehydrogenase
CF57_RS18810	COG2132	Multicopper oxidase
CF57_RS18835	COG1049	propionate catabolic process, 2-methylcitrate cycle
CF57_RS18840	COG3064	Membrane
CF57_RS18845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF57_RS18850	COG0508	dehydrogenase complex catalyzes the overall conversion of
CF57_RS18855	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CF57_RS18860	COG2186	Transcriptional regulator
CF57_RS18870	COG3725	Membrane protein required for beta-lactamase induction
CF57_RS18875	COG3023	N-Acetylmuramoyl-L-alanine amidase
CF57_RS18880	COG0157	Belongs to the NadC ModD family
CF57_RS18890	COG4969	Belongs to the N-Me-Phe pilin family
CF57_RS18895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CF57_RS18900	COG1459	type II secretion system
CF57_RS18910	COG0237	dephospho-CoA kinase activity
CF57_RS18930	COG0494	nUDIX hydrolase
CF57_RS18950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CF57_RS18955	COG0849	cell division
CF57_RS18960	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CF57_RS18965	COG1181	Belongs to the D-alanine--D-alanine ligase family
CF57_RS18980	COG0772	Belongs to the SEDS family
CF57_RS18985	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CF57_RS18995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CF57_RS19000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CF57_RS19005	COG0768	penicillin binding
CF57_RS19010	COG3116	cell division
CF57_RS19025	COG1609	Transcriptional regulator
CF57_RS19035	COG0440	acetolactate synthase activity
CF57_RS19040	COG0028	Belongs to the TPP enzyme family
CF57_RS19045	COG0583	DNA-binding transcription factor activity
CF57_RS19060	COG0473	3-isopropylmalate dehydrogenase activity
CF57_RS19075	COG2814	Major facilitator Superfamily
CF57_RS19085	COG4533	DNA binding
CF57_RS19090	COG4143	(ABC) transporter
CF57_RS19095	COG1178	ABC-type Fe3 transport system permease component
CF57_RS19105	COG0586	Pfam SNARE associated Golgi protein
CF57_RS19110	COG4977	sequence-specific DNA binding
CF57_RS19125	COG0235	Class ii aldolase
CF57_RS19130	COG0417	DNA replication proofreading
CF57_RS19140	COG0564	pseudouridine synthase activity
CF57_RS19145	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CF57_RS19150	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CF57_RS19155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CF57_RS19180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CF57_RS19195	COG2271	Major facilitator Superfamily
CF57_RS19200	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CF57_RS19205	COG0644	oxidoreductase
CF57_RS19275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CF57_RS19280	COG0505	Belongs to the CarA family
CF57_RS19310	COG1047	Peptidyl-prolyl cis-trans
CF57_RS19325	COG0196	riboflavin kinase activity
CF57_RS19345	COG1662	PFAM IS1 transposase
CF57_RS19350	COG1662	PFAM IS1 transposase
CF57_RS19355	COG3188	usher protein
CF57_RS19365	COG0583	DNA-binding transcription factor activity
CF57_RS19375	COG2963	transposase activity
CF57_RS19380	COG2801	Transposase and inactivated derivatives
CF57_RS19390	COG3385	transposase activity
CF57_RS19410	COG4735	regulation of single-species biofilm formation
CF57_RS19415	COG1584	GPR1 FUN34 yaaH family protein
CF57_RS19420	COG0521	Mo-molybdopterin cofactor biosynthetic process
CF57_RS19430	COG1115	amino acid carrier protein
CF57_RS19450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CF57_RS19460	COG0460	homoserine dehydrogenase
CF57_RS19460	COG0527	aspartate kinase activity
CF57_RS19470	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CF57_RS19480	COG0745	RESPONSE REGULATOR receiver
CF57_RS19490	COG2205	protein histidine kinase activity
CF57_RS19495	COG0745	RESPONSE REGULATOR receiver
CF57_RS19500	COG3045	CreA protein
CF57_RS19505	COG2207	Transcriptional regulator
CF57_RS19505	COG3708	Transcriptional regulator
CF57_RS19525	COG0741	lytic transglycosylase activity
CF57_RS19530	COG0488	(ABC) transporter
CF57_RS19540	COG3172	ATPase kinase involved in NAD metabolism
CF57_RS19540	COG1056	cytidyltransferase-related domain
CF57_RS19545	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CF57_RS19550	COG0560	Phosphoserine phosphatase
CF57_RS19555	COG3726	membrane protein affecting hemolysin expression
CF57_RS19595	COG1328	CTP reductase activity
CF57_RS19600	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CF57_RS19605	COG0084	hydrolase, TatD family'
CF57_RS19610	COG4667	esterase of the alpha-beta hydrolase superfamily
CF57_RS19620	COG2823	Periplasmic or secreted lipoprotein
CF57_RS19630	COG1011	Hydrolase
CF57_RS19635	COG0456	acetyltransferase
CF57_RS19640	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CF57_RS19675	COG4114	ferric iron reductase
CF57_RS19680	COG2197	response regulator
CF57_RS19685	COG2197	response regulator
CF57_RS19690	COG2966	Psort location CytoplasmicMembrane, score
CF57_RS19705	COG1484	DNA-dependent DNA replication
CF57_RS19720	COG1063	alcohol dehydrogenase
CF57_RS19725	COG1802	Transcriptional regulator
CF57_RS19730	COG2271	Major facilitator Superfamily
CF57_RS19735	COG0840	transmembrane signaling receptor activity
CF57_RS19740	COG1846	Transcriptional regulator
CF57_RS19745	COG0179	Fumarylacetoacetate (FAA) hydrolase
CF57_RS19750	COG1012	belongs to the aldehyde dehydrogenase family
CF57_RS19755	COG3384	dioxygenase
CF57_RS19765	COG3971	2-oxopent-4-enoate hydratase activity
CF57_RS19785	COG2368	4-hydroxyphenylacetate
CF57_RS19790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CF57_RS19800	COG1966	Carbon starvation protein
CF57_RS19805	COG2879	small protein
CF57_RS19810	COG0523	cobalamin synthesis protein
CF57_RS19815	COG1662	PFAM IS1 transposase
CF57_RS19820	COG2814	Major facilitator Superfamily
CF57_RS19825	COG2733	membrane
CF57_RS19835	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CF57_RS19840	COG1924	4 iron, 4 sulfur cluster binding
CF57_RS19855	COG0477	Major facilitator Superfamily
CF57_RS19865	COG3366	ferrous iron transmembrane transporter activity
CF57_RS19870	COG0700	Nucleoside recognition
CF57_RS19875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CF57_RS19880	COG0583	DNA-binding transcription factor activity
CF57_RS19905	COG2186	Transcriptional regulator
CF57_RS19915	COG0246	Mannitol dehydrogenase
CF57_RS19930	COG2610	gluconate transmembrane transporter activity
CF57_RS19935	COG3539	Fimbrial protein
CF57_RS19965	COG1662	PFAM IS1 transposase
CF57_RS19975	COG1595	DNA-templated transcription, initiation
CF57_RS19980	COG3712	iron ion homeostasis
CF57_RS19985	COG4772	TonB-dependent receptor
CF57_RS19990	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CF57_RS19995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF57_RS20000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF57_RS20005	COG1120	ATPase activity
CF57_RS20010	COG2085	NADP oxidoreductase coenzyme F420-dependent
CF57_RS20025	COG3436	PFAM IS66 Orf2 family protein
CF57_RS20030	COG4372	Transposase
CF57_RS20035	COG2826	transposase and inactivated derivatives, IS30 family
CF57_RS20045	COG1662	PFAM IS1 transposase
CF57_RS20090	COG3842	ATPase activity
CF57_RS20095	COG2040	homocysteine
CF57_RS20100	COG0833	amino acid
CF57_RS20105	COG3039	Transposase
CF57_RS20210	COG2826	transposase and inactivated derivatives, IS30 family
CF57_RS20215	COG2801	Transposase and inactivated derivatives
CF57_RS20235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF57_RS20320	COG3385	transposase activity
CF57_RS20385	COG1475	DNA binding
CF57_RS20680	COG3300	MHYT domain
CF57_RS20680	COG5001	Diguanylate cyclase
CF57_RS20725	COG1662	PFAM IS1 transposase
CF57_RS20760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CF57_RS20780	COG0697	spore germination
CF57_RS20795	COG1595	DNA-templated transcription, initiation
CF57_RS20800	COG3712	iron ion homeostasis
CF57_RS20805	COG4772	TonB-dependent receptor
CF57_RS20810	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CF57_RS20815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF57_RS20825	COG1120	ATPase activity
CF57_RS20830	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CF57_RS20835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF57_RS20840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF57_RS20845	COG1120	ATPase activity
CF57_RS20850	COG2085	NADP oxidoreductase coenzyme F420-dependent
CF57_RS20855	COG2963	transposase activity
CF57_RS20875	COG1064	alcohol dehydrogenase
CF57_RS20880	COG0433	COG0433 Predicted ATPase
CF57_RS20885	COG0795	lipopolysaccharide-transporting ATPase activity
CF57_RS20890	COG0795	lipopolysaccharide-transporting ATPase activity
CF57_RS20900	COG2927	DNA polymerase III (CHI subunit)
CF57_RS20910	COG4269	membrane
CF57_RS20915	COG0456	acetyltransferase
CF57_RS20920	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CF57_RS20935	COG2731	YhcH YjgK YiaL family protein
CF57_RS20940	COG1309	transcriptional regulator
CF57_RS20945	COG1028	Short-chain dehydrogenase reductase Sdr
CF57_RS20950	COG0251	oxidation-reduction process
CF57_RS20975	COG0251	oxidation-reduction process
CF57_RS20980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CF57_RS20985	COG1609	Transcriptional regulator
CF57_RS20990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS20990	COG1263	PTS System
CF57_RS20995	COG0366	Alpha amylase catalytic
CF57_RS21000	COG1328	CTP reductase activity
CF57_RS21005	COG0602	queuosine metabolic process
CF57_RS21010	COG3783	Cytochrome b(562)
CF57_RS21015	COG0312	modulator of DNA gyrase
CF57_RS21025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CF57_RS21035	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF57_RS21040	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF57_RS21045	COG1129	ABC transporter
CF57_RS21050	COG1879	ABC-type sugar transport system periplasmic component
CF57_RS21055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CF57_RS21060	COG2105	PFAM AIG2 family protein
CF57_RS21065	COG2911	Protein conserved in bacteria
CF57_RS21070	COG0729	surface antigen
CF57_RS21085	COG1253	flavin adenine dinucleotide binding
CF57_RS21095	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CF57_RS21100	COG1218	3'(2'),5'-bisphosphate nucleotidase
CF57_RS21105	COG0737	Belongs to the 5'-nucleotidase family
CF57_RS21110	COG1733	regulation of RNA biosynthetic process
CF57_RS21115	COG0702	epimerase
CF57_RS21120	COG0697	spore germination
CF57_RS21130	COG1113	amino acid transport
CF57_RS21135	COG0545	Peptidyl-prolyl cis-trans isomerase
CF57_RS21140	COG3061	Opacity-associated protein A
CF57_RS21145	COG1309	transcriptional regulator
CF57_RS21160	COG1024	Enoyl-CoA hydratase
CF57_RS21165	COG4670	ketone body catabolic process
CF57_RS21170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CF57_RS21175	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CF57_RS21185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CF57_RS21195	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CF57_RS21240	COG3414	Phosphotransferase system galactitol-specific IIB component
CF57_RS21245	COG3037	sugar-specific permease SgaT UlaA
CF57_RS21260	COG1073	alpha beta
CF57_RS21265	COG3650	response to hydrogen peroxide
CF57_RS21275	COG1960	acyl-CoA dehydrogenase activity
CF57_RS21280	COG0754	glutathionylspermidine amidase activity
CF57_RS21285	COG5463	Belongs to the UPF0441 family
CF57_RS21290	COG3766	membrane
CF57_RS21300	COG1842	Phage shock protein A
CF57_RS21305	COG3789	protein conserved in bacteria
CF57_RS21310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CF57_RS21315	COG0557	exoribonuclease II activity
CF57_RS21330	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CF57_RS21335	COG0330	HflC and HflK could
CF57_RS21340	COG0330	HflC and HflK could
CF57_RS21345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CF57_RS21365	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF57_RS21370	COG0802	atpase or kinase
CF57_RS21375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CF57_RS21375	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CF57_RS21380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CF57_RS21415	COG3264	Mechanosensitive ion channel
CF57_RS21415	COG1511	domain protein
CF57_RS21430	COG0531	amino acid
CF57_RS21440	COG1053	succinate dehydrogenase
CF57_RS21445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CF57_RS21460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF57_RS21465	COG3040	lipid binding
CF57_RS21470	COG2076	Multidrug Resistance protein
CF57_RS21475	COG5510	response to toxic substance
CF57_RS21480	COG5510	response to toxic substance
CF57_RS21490	COG1509	lysine 2,3-aminomutase activity
CF57_RS21515	COG0531	amino acid
CF57_RS21520	COG3030	protein affecting phage T7 exclusion by the F plasmid
CF57_RS21525	COG1027	Aspartate ammonia-lyase
CF57_RS21530	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CF57_RS21540	COG4232	protein-disulfide reductase activity
CF57_RS21545	COG1309	transcriptional regulator
CF57_RS21555	COG3710	Transcriptional regulator
CF57_RS21560	COG0531	amino acid
CF57_RS21565	COG1982	Orn Lys Arg decarboxylase major
CF57_RS21570	COG3104	oligopeptide transport
CF57_RS21575	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CF57_RS21590	COG2388	GCN5-related N-acetyl-transferase
CF57_RS21595	COG3592	Divergent 4Fe-4S mono-cluster
CF57_RS21600	COG3290	protein histidine kinase activity
CF57_RS21605	COG4565	transcriptional regulatory protein
CF57_RS21615	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CF57_RS21620	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CF57_RS21620	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CF57_RS21625	COG3647	Membrane
CF57_RS21630	COG2211	Major facilitator Superfamily
CF57_RS21635	COG1486	melibiose metabolic process
CF57_RS21645	COG2169	Transcriptional regulator
CF57_RS21650	COG1982	Orn Lys Arg decarboxylase major
CF57_RS21655	COG2207	Transcriptional regulator
CF57_RS21660	COG1662	PFAM IS1 transposase
CF57_RS21665	COG0531	amino acid
CF57_RS21670	COG2194	sulfuric ester hydrolase activity
CF57_RS21675	COG0745	RESPONSE REGULATOR receiver
CF57_RS21680	COG0642	Histidine kinase
CF57_RS21690	COG0477	Major facilitator Superfamily
CF57_RS21705	COG2824	Alkylphosphonate utilization operon protein PhnA
CF57_RS21710	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CF57_RS21720	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CF57_RS21725	COG3639	organic phosphonate transmembrane transporter activity
CF57_RS21730	COG2188	Transcriptional regulator
CF57_RS21735	COG3624	Phosphonate C-P lyase system protein PhnG
CF57_RS21740	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CF57_RS21745	COG3626	phosphonate metabolism
CF57_RS21750	COG3627	carbon phosphorus lyase activity
CF57_RS21755	COG4107	phosphonate C-P lyase system protein PhnK
CF57_RS21760	COG4778	phosphonate C-P lyase system protein PhnL
CF57_RS21765	COG3454	Phosphonate metabolism
CF57_RS21770	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CF57_RS21775	COG0456	acetyltransferase
CF57_RS21780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CF57_RS21790	COG0698	ribose 5-phosphate isomerase
CF57_RS21795	COG1737	Transcriptional regulator
CF57_RS21800	COG1879	ABC-type sugar transport system periplasmic component
CF57_RS21805	COG1129	ABC transporter
CF57_RS21810	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF57_RS21815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CF57_RS21820	COG1940	carbohydrate kinase activity
CF57_RS21825	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CF57_RS21835	COG1566	PFAM secretion protein HlyD family protein
CF57_RS21840	COG1289	transmembrane transporter activity
CF57_RS21845	COG1538	Outer membrane efflux protein
CF57_RS21850	COG3383	formate dehydrogenase (NAD+) activity
CF57_RS21855	COG3383	formate dehydrogenase (NAD+) activity
CF57_RS21860	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CF57_RS21865	COG1301	dicarboxylic acid transport
CF57_RS21870	COG4235	cytochrome complex assembly
CF57_RS21875	COG3088	subunit of a heme lyase
CF57_RS21880	COG1138	Cytochrome C-type biogenesis protein
CF57_RS21885	COG3301	Polysulphide reductase, NrfD
CF57_RS21890	COG0437	4 iron, 4 sulfur cluster binding
CF57_RS21895	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CF57_RS21905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CF57_RS21910	COG3162	membrane
CF57_RS21920	COG1357	PFAM Pentapeptide repeats (8 copies)
CF57_RS21925	COG0025	NhaP-type Na H and K H
CF57_RS21930	COG2252	PERMEase
CF57_RS21935	COG0789	Transcriptional regulator
CF57_RS21940	COG2207	Transcriptional regulator
CF57_RS21945	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CF57_RS21955	COG0629	single-stranded DNA binding
CF57_RS21960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CF57_RS21965	COG2315	Protein conserved in bacteria
CF57_RS21975	COG3700	Belongs to the class B bacterial acid phosphatase family
CF57_RS21985	COG1448	Aminotransferase
CF57_RS21990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CF57_RS21995	COG0305	Participates in initiation and elongation during chromosome replication
CF57_RS22000	COG0604	alcohol dehydrogenase
CF57_RS22010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CF57_RS22025	COG0735	belongs to the Fur family
CF57_RS22030	COG3237	CsbD-like
CF57_RS22035	COG0534	Mate efflux family protein
CF57_RS22045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CF57_RS22065	COG1357	PFAM Pentapeptide repeats (8 copies)
CF57_RS22085	COG3842	ATPase activity
CF57_RS22095	COG2182	Extracellular solute-binding protein
CF57_RS22100	COG1175	transmembrane transport
CF57_RS22105	COG3833	ABC-type maltose transport systems, permease component
CF57_RS22110	COG2814	Major facilitator Superfamily
CF57_RS22110	COG0477	Major facilitator Superfamily
CF57_RS22135	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF57_RS22160	COG0527	aspartate kinase activity
CF57_RS22170	COG1187	pseudouridine synthase activity
CF57_RS22180	COG1283	sodium-dependent phosphate transmembrane transporter activity
CF57_RS22185	COG0646	methionine synthase
CF57_RS22185	COG1410	methionine synthase
CF57_RS22190	COG1414	Transcriptional regulator
CF57_RS22205	COG2224	Isocitrate lyase
CF57_RS22210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CF57_RS22220	COG0456	acetyltransferase
CF57_RS22250	COG0151	Belongs to the GarS family
CF57_RS22255	COG2204	response regulator
CF57_RS22260	COG4191	Histidine kinase
CF57_RS22265	COG3678	ATP-independent chaperone mediated protein folding
CF57_RS22280	COG3068	Protein conserved in bacteria
CF57_RS22315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CF57_RS22320	COG2104	thiamine diphosphate biosynthetic process
CF57_RS22330	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CF57_RS22370	COG0250	Participates in transcription elongation, termination and antitermination
CF57_RS22375	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CF57_RS22415	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CF57_RS22415	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CF57_RS22445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CF57_RS22450	COG4206	TonB-dependent receptor
CF57_RS22475	COG0583	DNA-binding transcription factor activity
CF57_RS22490	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CF57_RS22510	COG2194	sulfuric ester hydrolase activity
CF57_RS22515	COG2207	Transcriptional regulator
CF57_RS22525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS22530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CF57_RS22535	COG1882	Formate acetyltransferase
CF57_RS22540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS22545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS22550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS22550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF57_RS22550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS22555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CF57_RS22560	COG0371	Dehydrogenase
CF57_RS22575	COG0697	spore germination
CF57_RS22585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CF57_RS22595	COG0527	aspartate kinase activity
CF57_RS22595	COG0460	homoserine dehydrogenase
CF57_RS22600	COG0626	cystathionine gamma-synthase activity
CF57_RS22610	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CF57_RS22635	COG3209	COG3209 Rhs family protein
CF57_RS22635	COG3209	COG3209 Rhs family protein
CF57_RS22645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CF57_RS22650	COG1609	Transcriptional regulator
CF57_RS22655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CF57_RS22670	COG1575	Belongs to the MenA family. Type 1 subfamily
CF57_RS22685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CF57_RS22695	COG1494	fructose-1,6-bisphosphatase
CF57_RS22700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF57_RS22705	COG0589	response to stress
CF57_RS22710	COG3691	Protein conserved in bacteria
CF57_RS22715	COG3152	Membrane
CF57_RS22735	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CF57_RS22750	COG3678	ATP-independent chaperone mediated protein folding
CF57_RS22755	COG0745	RESPONSE REGULATOR receiver
CF57_RS22760	COG2205	protein histidine kinase activity
CF57_RS22765	COG2258	MOSC domain
CF57_RS22780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CF57_RS22830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS22835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS22835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF57_RS22840	COG1363	Peptidase, m42
CF57_RS22845	COG3711	transcriptional antiterminator
CF57_RS22845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF57_RS22860	COG3383	formate dehydrogenase (NAD+) activity
CF57_RS22860	COG0243	molybdopterin cofactor binding
CF57_RS22865	COG3383	formate dehydrogenase (NAD+) activity
CF57_RS22865	COG0243	molybdopterin cofactor binding
CF57_RS22870	COG0437	4 iron, 4 sulfur cluster binding
CF57_RS22875	COG2864	formate dehydrogenase
CF57_RS22890	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CF57_RS22895	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CF57_RS22900	COG0456	acetyltransferase
CF57_RS22915	COG1011	Hydrolase
CF57_RS22920	COG1349	DNA-binding transcription factor activity
CF57_RS22925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF57_RS22930	COG2084	Dehydrogenase
CF57_RS22935	COG3684	Belongs to the aldolase LacD family
CF57_RS22940	COG2942	2-epimerase
CF57_RS22945	COG2017	converts alpha-aldose to the beta-anomer
CF57_RS22955	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CF57_RS22960	COG2271	Major facilitator Superfamily
CF57_RS22965	COG1082	Xylose isomerase domain protein TIM barrel
CF57_RS22970	COG2188	Transcriptional regulator
CF57_RS22975	COG1217	gtp-binding protein TYPA
CF57_RS22985	COG0174	glutamine synthetase
CF57_RS22990	COG3852	Histidine kinase
CF57_RS22995	COG2204	response regulator
CF57_RS23005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CF57_RS23020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CF57_RS23020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CF57_RS23030	COG0204	Acyl-transferase
CF57_RS23035	COG5339	Protein conserved in bacteria
CF57_RS23040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CF57_RS23045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CF57_RS23050	COG3084	Protein conserved in bacteria
CF57_RS23055	COG0746	molybdenum cofactor guanylyltransferase activity
CF57_RS23060	COG1763	Mo-molybdopterin cofactor biosynthetic process
CF57_RS23090	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CF57_RS23095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CF57_RS23100	COG1739	Uncharacterized protein family UPF0029
CF57_RS23115	COG0183	Belongs to the thiolase family
CF57_RS23120	COG0543	2 iron, 2 sulfur cluster binding
CF57_RS23125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CF57_RS23130	COG0250	Participates in transcription elongation, termination and antitermination
CF57_RS23135	COG0084	hydrolase, TatD family'
CF57_RS23140	COG0805	protein transport
CF57_RS23145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CF57_RS23150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CF57_RS23160	COG3165	ubiquinone biosynthetic process from chorismate
CF57_RS23170	COG1322	Protein conserved in bacteria
CF57_RS23175	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CF57_RS23180	COG0412	Dienelactone hydrolase
CF57_RS23190	COG0583	DNA-binding transcription factor activity
CF57_RS23195	COG0697	spore germination
CF57_RS23200	COG0561	phosphatase activity
CF57_RS23205	COG2267	carboxylic ester hydrolase activity
CF57_RS23210	COG1280	lysine exporter protein (LysE YggA)
CF57_RS23215	COG1280	lysine exporter protein (LysE YggA)
CF57_RS23220	COG0514	ATP-dependent DNA helicase (RecQ)
CF57_RS23225	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CF57_RS23230	COG2050	protein possibly involved in aromatic compounds catabolism
CF57_RS23235	COG2962	Rard protein
CF57_RS23250	COG0598	Magnesium transport protein CorA
CF57_RS23255	COG3698	Phosphodiester glycosidase
CF57_RS23260	COG0210	DNA helicase
CF57_RS23265	COG1011	Hydrolase
CF57_RS23275	COG3159	Protein conserved in bacteria
CF57_RS23285	COG5567	small periplasmic lipoprotein
CF57_RS23295	COG3072	Adenylate cyclase
CF57_RS23305	COG1587	Uroporphyrinogen-III synthase
CF57_RS23310	COG2959	enzyme of heme biosynthesis
CF57_RS23315	COG3071	HemY protein
CF57_RS23320	COG3119	arylsulfatase activity
CF57_RS23325	COG0641	radical SAM
CF57_RS23350	COG1113	amino acid transport
CF57_RS23370	COG2244	polysaccharide biosynthetic process
CF57_RS23375	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CF57_RS23380	COG0456	acetyltransferase
CF57_RS23385	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CF57_RS23390	COG1088	dTDP-glucose 4,6-dehydratase activity
CF57_RS23395	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CF57_RS23400	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CF57_RS23405	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CF57_RS23410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CF57_RS23420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CF57_RS23430	COG3118	belongs to the thioredoxin family
CF57_RS23445	COG0210	DNA helicase
CF57_RS23465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CF57_RS23475	COG0583	DNA-binding transcription factor activity
CF57_RS23480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CF57_RS23490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CF57_RS23495	COG3978	acetolactate synthase activity
CF57_RS23510	COG0606	chelatase, subunit chli
CF57_RS23515	COG3085	chromosome segregation
CF57_RS23545	COG0456	acetyltransferase
CF57_RS23625	COG3085	chromosome segregation
CF57_RS23635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF57_RS23640	COG1609	Transcriptional regulator
CF57_RS23645	COG0477	Major facilitator Superfamily
CF57_RS23650	COG2186	Transcriptional regulator
CF57_RS23680	COG0477	Major facilitator Superfamily
CF57_RS23685	COG5544	Lipoprotein
CF57_RS23690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CF57_RS23705	COG3118	belongs to the thioredoxin family
CF57_RS23735	COG0477	Major facilitator Superfamily
CF57_RS23740	COG1609	Transcriptional regulator
CF57_RS23745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF57_RS23750	COG1879	ABC-type sugar transport system periplasmic component
CF57_RS23755	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF57_RS23760	COG1129	ABC transporter
CF57_RS23790	COG1522	sequence-specific DNA binding
CF57_RS23795	COG0716	FMN binding
CF57_RS23810	COG3312	ion transport
CF57_RS23865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CF57_RS23870	COG0573	inorganic phosphate transmembrane transporter activity
CF57_RS23875	COG0581	inorganic phosphate transmembrane transporter activity
CF57_RS23880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CF57_RS23885	COG0704	Plays a role in the regulation of phosphate uptake
CF57_RS23890	COG3711	transcriptional antiterminator
CF57_RS23895	COG2190	(PTS) system
CF57_RS23895	COG1263	PTS System
CF57_RS23895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF57_RS23900	COG2723	6-phospho-beta-galactosidase activity
CF57_RS23910	COG2382	esterase
CF57_RS23915	COG0363	glucosamine-6-phosphate deaminase activity
CF57_RS23920	COG3196	Protein conserved in bacteria
CF57_RS23935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF57_RS23940	COG2252	PERMEase
CF57_RS23945	COG0431	NADPH-dependent FMN reductase
CF57_RS23950	COG2091	lysine biosynthetic process via aminoadipic acid
CF57_RS23965	COG0814	amino acid
CF57_RS24065	COG0534	Mate efflux family protein
CF57_RS24070	COG0534	Mate efflux family protein
CF57_RS24075	COG3209	COG3209 Rhs family protein
CF57_RS24095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF57_RS24100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily