locus-tag	class	description
CF61_RS00010	COG0592	DNA-directed DNA polymerase activity
CF61_RS00020	COG0187	DNA topoisomerase II activity
CF61_RS00030	COG3753	Protein conserved in bacteria
CF61_RS00035	COG0561	phosphatase activity
CF61_RS00045	COG2186	Transcriptional regulator
CF61_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
CF61_RS00055	COG0800	Aldolase
CF61_RS00065	COG2271	Major facilitator Superfamily
CF61_RS00075	COG0823	Involved in the tonB-independent uptake of proteins
CF61_RS00080	COG5645	(Lipo)protein
CF61_RS00100	COG2188	Transcriptional regulator
CF61_RS00120	COG0675	Transposase, IS605 OrfB family
CF61_RS00125	COG2149	membrane
CF61_RS00135	COG0641	radical SAM
CF61_RS00140	COG2814	Major facilitator Superfamily
CF61_RS00160	COG0028	Belongs to the TPP enzyme family
CF61_RS00165	COG0440	acetolactate synthase activity
CF61_RS00170	COG2197	response regulator
CF61_RS00175	COG3851	Histidine kinase
CF61_RS00180	COG2271	Major facilitator Superfamily
CF61_RS00185	COG2271	Major facilitator Superfamily
CF61_RS00195	COG2252	PERMEase
CF61_RS00220	COG1464	Belongs to the NlpA lipoprotein family
CF61_RS00225	COG0697	spore germination
CF61_RS00230	COG2814	Major facilitator Superfamily
CF61_RS00245	COG2211	Major facilitator Superfamily
CF61_RS00250	COG1501	Belongs to the glycosyl hydrolase 31 family
CF61_RS00255	COG2982	Protein involved in outer membrane biogenesis
CF61_RS00260	COG2233	PERMEase
CF61_RS00265	COG0786	glutamate:sodium symporter activity
CF61_RS00270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CF61_RS00275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CF61_RS00280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CF61_RS00290	COG0194	GDP metabolic process
CF61_RS00300	COG2860	membrane
CF61_RS00310	COG1561	YicC-like family, N-terminal region
CF61_RS00335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CF61_RS00365	COG1519	Transferase
CF61_RS00370	COG0859	PFAM glycosyl transferase family 9
CF61_RS00375	COG0438	transferase activity, transferring glycosyl groups
CF61_RS00380	COG0515	serine threonine protein kinase
CF61_RS00395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CF61_RS00425	COG0515	serine threonine protein kinase
CF61_RS00465	COG3192	ethanolamine utilization protein
CF61_RS00475	COG4303	Ethanolamine ammonia lyase large subunit
CF61_RS00495	COG2823	Periplasmic or secreted lipoprotein
CF61_RS00505	COG1011	Hydrolase
CF61_RS00510	COG0456	acetyltransferase
CF61_RS00515	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CF61_RS00555	COG4114	ferric iron reductase
CF61_RS00610	COG0582	viral genome integration into host DNA
CF61_RS00655	COG4712	double-strand break repair protein
CF61_RS00725	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CF61_RS00730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CF61_RS00735	COG2011	ABC-type metal ion transport system permease component
CF61_RS00750	COG1720	tRNA m6t6A37 methyltransferase activity
CF61_RS00760	COG0791	NLP P60 protein
CF61_RS00765	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS00800	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CF61_RS00805	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS00820	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CF61_RS00825	COG5557	Pfam Polysulphide reductase, NrfD
CF61_RS00830	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS00930	COG1442	glycosyl transferase family 8
CF61_RS00935	COG1216	Glycosyl transferase, family 2
CF61_RS00940	COG3307	-O-antigen
CF61_RS00945	COG0859	PFAM glycosyl transferase family 9
CF61_RS00950	COG0859	PFAM glycosyl transferase family 9
CF61_RS00960	COG0156	8-amino-7-oxononanoate synthase activity
CF61_RS00970	COG1216	Glycosyl transferase, family 2
CF61_RS00975	COG2861	carbohydrate metabolic process
CF61_RS00980	COG4942	peptidase
CF61_RS00990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF61_RS00995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CF61_RS01010	COG1045	serine acetyltransferase
CF61_RS01015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CF61_RS01025	COG2186	Transcriptional regulator
CF61_RS01030	COG1620	l-lactate permease
CF61_RS01035	COG5295	Hep Hag repeat protein
CF61_RS01055	COG3722	fumarate hydratase activity
CF61_RS01065	COG2213	PTS system mannitol-specific
CF61_RS01065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS01075	COG1566	PFAM secretion protein HlyD family protein
CF61_RS01085	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CF61_RS01090	COG3209	COG3209 Rhs family protein
CF61_RS01095	COG1413	lyase activity
CF61_RS01100	COG3209	COG3209 Rhs family protein
CF61_RS01105	COG0625	glutathione transferase activity
CF61_RS01115	COG3276	selenocysteine insertion sequence binding
CF61_RS01120	COG1454	alcohol dehydrogenase
CF61_RS01125	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS01140	COG1566	PFAM secretion protein HlyD family protein
CF61_RS01145	COG0583	DNA-binding transcription factor activity
CF61_RS01150	COG3713	MltA-interacting MipA family protein
CF61_RS01160	COG2211	Major facilitator Superfamily
CF61_RS01170	COG0235	Class ii aldolase
CF61_RS01175	COG3623	hexulose-6-phosphate isomerase
CF61_RS01180	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CF61_RS01185	COG1070	Carbohydrate kinase
CF61_RS01190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CF61_RS01195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CF61_RS01200	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CF61_RS01205	COG2731	YhcH YjgK YiaL family protein
CF61_RS01215	COG1414	Transcriptional regulator
CF61_RS01220	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS01230	COG3977	Valine--pyruvate aminotransferase
CF61_RS01235	COG0366	Alpha amylase catalytic
CF61_RS01240	COG2992	FlgJ-related protein
CF61_RS01245	COG2207	Transcriptional regulator
CF61_RS01245	COG1609	Transcriptional regulator
CF61_RS01250	COG4214	carbohydrate transport
CF61_RS01255	COG1129	ABC transporter
CF61_RS01260	COG4213	ABC transporter substrate-binding protein
CF61_RS01270	COG1070	Carbohydrate kinase
CF61_RS01275	COG4682	membrane
CF61_RS01280	COG4682	membrane
CF61_RS01285	COG3274	enterobacterial common antigen metabolic process
CF61_RS01305	COG2963	transposase activity
CF61_RS01310	COG2801	Transposase and inactivated derivatives
CF61_RS01320	COG1278	Cold shock
CF61_RS01325	COG2944	sequence-specific DNA binding
CF61_RS01340	COG2885	chlorophyll binding
CF61_RS01345	COG0243	molybdopterin cofactor binding
CF61_RS01350	COG0456	acetyltransferase
CF61_RS01355	COG2818	Glycosylase
CF61_RS01360	COG5571	outer membrane autotransporter
CF61_RS01365	COG2223	nitrite transmembrane transporter activity
CF61_RS01370	COG2194	sulfuric ester hydrolase activity
CF61_RS01385	COG0747	negative chemotaxis
CF61_RS01395	COG0601	transmembrane transport
CF61_RS01400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF61_RS01405	COG0444	Belongs to the ABC transporter superfamily
CF61_RS01410	COG4608	Belongs to the ABC transporter superfamily
CF61_RS01415	COG0814	amino acid
CF61_RS01430	COG2194	sulfuric ester hydrolase activity
CF61_RS01470	COG1215	transferase activity, transferring glycosyl groups
CF61_RS01475	COG1215	transferase activity, transferring glycosyl groups
CF61_RS01480	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CF61_RS01485	COG3118	belongs to the thioredoxin family
CF61_RS01485	COG0457	Tetratricopeptide repeat
CF61_RS01490	COG2200	EAL domain
CF61_RS01490	COG2199	diguanylate cyclase activity
CF61_RS01500	COG0612	Peptidase, M16
CF61_RS01505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF61_RS01515	COG2200	EAL domain
CF61_RS01520	COG2982	Protein involved in outer membrane biogenesis
CF61_RS01525	COG0477	Major facilitator Superfamily
CF61_RS01530	COG1295	ribonuclease BN
CF61_RS01535	COG0583	DNA-binding transcription factor activity
CF61_RS01540	COG2197	response regulator
CF61_RS01550	COG1858	cytochrome C peroxidase
CF61_RS01565	COG1858	cytochrome C peroxidase
CF61_RS01570	COG0076	glutamate decarboxylase activity
CF61_RS01585	COG2207	Transcriptional regulator
CF61_RS01590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF61_RS01595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF61_RS01605	COG2771	luxR family
CF61_RS01610	COG3247	response to pH
CF61_RS01625	COG1285	pathogenesis
CF61_RS01630	COG2197	response regulator
CF61_RS01635	COG3065	identical protein binding
CF61_RS01645	COG1393	Belongs to the ArsC family
CF61_RS01650	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CF61_RS01655	COG0640	Transcriptional regulator
CF61_RS01670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF61_RS01675	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CF61_RS01680	COG0339	signal peptide processing
CF61_RS01690	COG3104	oligopeptide transport
CF61_RS01695	COG0589	response to stress
CF61_RS01705	COG0306	phosphate transporter
CF61_RS01710	COG2081	HI0933 family
CF61_RS01725	COG2801	Transposase and inactivated derivatives
CF61_RS01780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF61_RS01785	COG0842	Transport permease protein
CF61_RS01785	COG1129	ABC transporter
CF61_RS01790	COG0842	Transport permease protein
CF61_RS01795	COG5433	transposase activity
CF61_RS01810	COG3209	COG3209 Rhs family protein
CF61_RS01820	COG1124	(ABC) transporter
CF61_RS01825	COG0444	Belongs to the ABC transporter superfamily
CF61_RS01830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF61_RS01835	COG0601	transmembrane transport
CF61_RS01840	COG0747	negative chemotaxis
CF61_RS01845	COG2091	lysine biosynthetic process via aminoadipic acid
CF61_RS01850	COG0628	permease
CF61_RS01855	COG0477	Major facilitator Superfamily
CF61_RS01865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CF61_RS01880	COG3714	YhhN family
CF61_RS01890	COG3776	membrane
CF61_RS01895	COG0742	ribosomal rna small subunit methyltransferase
CF61_RS01900	COG0552	protein localization to endoplasmic reticulum
CF61_RS01905	COG2884	Cell division ATP-binding protein ftsE
CF61_RS01910	COG2177	Part of the ABC transporter FtsEX involved in
CF61_RS01915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CF61_RS01920	COG0683	leucine binding
CF61_RS01930	COG0456	acetyltransferase
CF61_RS01935	COG0683	leucine binding
CF61_RS01940	COG0559	Belongs to the binding-protein-dependent transport system permease family
CF61_RS01945	COG4177	L-phenylalanine transmembrane transporter activity
CF61_RS01950	COG0411	ABC transporter
CF61_RS01955	COG0410	ABC transporter
CF61_RS01965	COG1653	transport
CF61_RS01970	COG1175	transmembrane transport
CF61_RS01975	COG0395	ABC-type sugar transport system, permease component
CF61_RS01980	COG3842	ATPase activity
CF61_RS01985	COG0584	glycerophosphoryl diester phosphodiesterase
CF61_RS01995	COG0405	Gamma-glutamyltransferase
CF61_RS02010	COG3157	Type VI secretion system effector, Hcp
CF61_RS02015	COG1247	-acetyltransferase
CF61_RS02020	COG0673	inositol 2-dehydrogenase activity
CF61_RS02025	COG1741	Belongs to the pirin family
CF61_RS02030	COG1609	Transcriptional regulator
CF61_RS02035	COG3265	gluconokinase activity
CF61_RS02040	COG2610	gluconate transmembrane transporter activity
CF61_RS02045	COG2095	MarC family integral membrane protein
CF61_RS02050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CF61_RS02075	COG0058	SHG alpha-glucan phosphorylase activity
CF61_RS02080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CF61_RS02100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CF61_RS02115	COG1349	DNA-binding transcription factor activity
CF61_RS02120	COG4650	regulator
CF61_RS02125	COG1690	Belongs to the RtcB family
CF61_RS02140	COG0058	SHG alpha-glucan phosphorylase activity
CF61_RS02145	COG1640	4-alpha-glucanotransferase
CF61_RS02150	COG2610	gluconate transmembrane transporter activity
CF61_RS02170	COG5464	transposase or invertase
CF61_RS02180	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CF61_RS02185	COG1918	ferrous iron import across plasma membrane
CF61_RS02190	COG2183	response to ionizing radiation
CF61_RS02195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CF61_RS02220	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CF61_RS02230	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CF61_RS02235	COG1011	Hydrolase
CF61_RS02245	COG0494	nUDIX hydrolase
CF61_RS02250	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CF61_RS02255	COG4972	Pilus assembly protein
CF61_RS02260	COG3166	PFAM Fimbrial assembly family protein
CF61_RS02275	COG4796	Type ii and iii secretion system protein
CF61_RS02290	COG3266	domain, Protein
CF61_RS02295	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CF61_RS02300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CF61_RS02305	COG0546	phosphoglycolate phosphatase activity
CF61_RS02310	COG0180	Tryptophanyl-tRNA synthetase
CF61_RS02315	COG2188	Transcriptional regulator
CF61_RS02325	COG3457	Alanine racemase
CF61_RS02330	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CF61_RS02335	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CF61_RS02350	COG0626	cystathionine gamma-synthase activity
CF61_RS02355	COG2188	Transcriptional regulator
CF61_RS02360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF61_RS02365	COG1082	Xylose isomerase domain protein TIM barrel
CF61_RS02370	COG2222	sugar isomerase
CF61_RS02375	COG0531	amino acid
CF61_RS02390	COG2116	formate transmembrane transporter activity
CF61_RS02395	COG2146	nitrite reductase [NAD(P)H] activity
CF61_RS02400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CF61_RS02410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CF61_RS02420	COG2184	nucleotidyltransferase activity
CF61_RS02425	COG0512	Glutamine amidotransferase of anthranilate synthase
CF61_RS02430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CF61_RS02435	COG1289	transmembrane transporter activity
CF61_RS02440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF61_RS02450	COG1765	OsmC-like protein
CF61_RS02455	COG3954	Phosphoribulokinase
CF61_RS02465	COG0429	hydrolase of the alpha beta-hydrolase fold
CF61_RS02470	COG0488	(ABC) transporter
CF61_RS02485	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CF61_RS02490	COG1047	Peptidyl-prolyl cis-trans
CF61_RS02500	COG0545	Peptidyl-prolyl cis-trans isomerase
CF61_RS02505	COG2964	Protein conserved in bacteria
CF61_RS02545	COG3979	chitinase
CF61_RS02550	COG2906	2 iron, 2 sulfur cluster binding
CF61_RS02555	COG2193	ferroxidase activity
CF61_RS02560	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CF61_RS02565	COG1662	PFAM IS1 transposase
CF61_RS02570	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CF61_RS02575	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CF61_RS02580	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CF61_RS02585	COG3156	type II secretion system protein K
CF61_RS02590	COG4795	General secretion pathway protein
CF61_RS02595	COG2165	general secretion pathway protein
CF61_RS02600	COG2165	general secretion pathway protein
CF61_RS02605	COG2165	general secretion pathway protein
CF61_RS02610	COG1459	type II secretion system
CF61_RS02620	COG1450	Type ii and iii secretion system protein
CF61_RS02625	COG3031	protein transport across the cell outer membrane
CF61_RS02630	COG3267	Type II secretory pathway component ExeA
CF61_RS02630	COG3409	Peptidoglycan-binding domain 1 protein
CF61_RS02655	COG0089	rRNA binding
CF61_RS02745	COG0201	protein transport
CF61_RS02785	COG0789	Transcriptional regulator
CF61_RS02790	COG3036	rescue of stalled ribosome
CF61_RS02800	COG0569	domain protein
CF61_RS02820	COG0758	DNA mediated transformation
CF61_RS02830	COG0551	DNA topoisomerase type I activity
CF61_RS02850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CF61_RS02915	COG1126	abc transporter atp-binding protein
CF61_RS02920	COG0765	amino acid transport
CF61_RS02925	COG4597	amino acid ABC transporter
CF61_RS02930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF61_RS02945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF61_RS02950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF61_RS02955	COG1309	transcriptional regulator
CF61_RS02965	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CF61_RS02975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CF61_RS02985	COG4145	pantothenate transmembrane transporter activity
CF61_RS02990	COG3924	membrane
CF61_RS02995	COG0439	Biotin carboxylase
CF61_RS03000	COG0511	ligase activity, forming carbon-carbon bonds
CF61_RS03020	COG0604	alcohol dehydrogenase
CF61_RS03025	COG2199	diguanylate cyclase activity
CF61_RS03025	COG2200	EAL domain
CF61_RS03035	COG1077	Cell shape determining protein MreB Mrl
CF61_RS03040	COG1792	Involved in formation and maintenance of cell shape
CF61_RS03045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CF61_RS03055	COG1530	ribonuclease E activity
CF61_RS03060	COG3164	Protein of unknown function
CF61_RS03065	COG0312	modulator of DNA gyrase
CF61_RS03070	COG0583	DNA-binding transcription factor activity
CF61_RS03090	COG2732	(Barnase) inhibitor
CF61_RS03110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF61_RS03115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF61_RS03120	COG3105	Protein conserved in bacteria
CF61_RS03125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CF61_RS03140	COG0625	glutathione transferase activity
CF61_RS03145	COG2969	positive regulation of protein catabolic process
CF61_RS03150	COG3069	C4-dicarboxylate transmembrane transporter activity
CF61_RS03180	COG2731	YhcH YjgK YiaL family protein
CF61_RS03190	COG4804	nuclease activity
CF61_RS03195	COG0493	'glutamate synthase
CF61_RS03200	COG0070	glutamate synthase
CF61_RS03200	COG0069	glutamate synthase activity
CF61_RS03200	COG0067	glutamate synthase
CF61_RS03205	COG1242	4 iron, 4 sulfur cluster binding
CF61_RS03210	COG2198	Histidine kinase
CF61_RS03210	COG5002	protein histidine kinase activity
CF61_RS03210	COG0784	Response regulator, receiver
CF61_RS03215	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CF61_RS03225	COG0515	serine threonine protein kinase
CF61_RS03230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS03245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CF61_RS03250	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CF61_RS03255	COG1137	ATPase activity
CF61_RS03260	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CF61_RS03265	COG3117	lipopolysaccharide transmembrane transporter activity
CF61_RS03270	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CF61_RS03275	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CF61_RS03275	COG0517	IMP dehydrogenase activity
CF61_RS03280	COG0530	calcium, potassium:sodium antiporter activity
CF61_RS03285	COG1127	ABC transporter
CF61_RS03290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CF61_RS03295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CF61_RS03300	COG2854	intermembrane phospholipid transfer
CF61_RS03305	COG3113	response to antibiotic
CF61_RS03310	COG5007	Belongs to the BolA IbaG family
CF61_RS03320	COG3423	Transcriptional regulator
CF61_RS03325	COG0142	geranyltranstransferase activity
CF61_RS03340	COG0697	spore germination
CF61_RS03350	COG2027	D-alanyl-D-alanine carboxypeptidase
CF61_RS03355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CF61_RS03360	COG1534	Rna-binding protein
CF61_RS03370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CF61_RS03375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CF61_RS03385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CF61_RS03395	COG2194	sulfuric ester hydrolase activity
CF61_RS03415	COG0195	Participates in both transcription termination and antitermination
CF61_RS03450	COG0513	Belongs to the DEAD box helicase family
CF61_RS03460	COG0814	amino acid
CF61_RS03465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CF61_RS03470	COG0826	peptidase U32
CF61_RS03475	COG0826	peptidase U32
CF61_RS03480	COG3154	lipid carrier protein
CF61_RS03485	COG3153	acetyltransferase
CF61_RS03500	COG0693	protein deglycase activity
CF61_RS03505	COG0702	epimerase
CF61_RS03510	COG0701	Predicted permease
CF61_RS03515	COG2823	Periplasmic or secreted lipoprotein
CF61_RS03530	COG3107	peptidoglycan biosynthetic process
CF61_RS03535	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CF61_RS03540	COG3539	Fimbrial protein
CF61_RS03545	COG3188	usher protein
CF61_RS03550	COG3121	Chaperone
CF61_RS03555	COG3539	Fimbrial protein
CF61_RS03560	COG0363	glucosamine-6-phosphate deaminase activity
CF61_RS03565	COG3716	PTS system mannose fructose sorbose family IID component
CF61_RS03570	COG3715	PTS system
CF61_RS03575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS03585	COG2222	sugar isomerase
CF61_RS03590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CF61_RS03595	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS03600	COG3716	PTS system mannose fructose sorbose family IID component
CF61_RS03610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS03620	COG1349	DNA-binding transcription factor activity
CF61_RS03630	COG2002	toxin-antitoxin pair type II binding
CF61_RS03635	COG2721	sulfolactate sulfo-lyase activity
CF61_RS03640	COG2271	Major facilitator Superfamily
CF61_RS03650	COG2084	Dehydrogenase
CF61_RS03655	COG1929	Belongs to the glycerate kinase type-1 family
CF61_RS03675	COG0583	DNA-binding transcription factor activity
CF61_RS03680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CF61_RS03690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CF61_RS03695	COG1882	Formate acetyltransferase
CF61_RS03700	COG0251	oxidation-reduction process
CF61_RS03705	COG1760	l-serine dehydratase
CF61_RS03710	COG0814	amino acid
CF61_RS03725	COG1741	Belongs to the pirin family
CF61_RS03730	COG0583	DNA-binding transcription factor activity
CF61_RS03735	COG3152	Membrane
CF61_RS03740	COG3152	Membrane
CF61_RS03745	COG0435	Glutathione S-transferase
CF61_RS03750	COG2259	Doxx family
CF61_RS03760	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CF61_RS03765	COG4575	ribosome binding
CF61_RS03770	COG1422	Protein of unknown function (DUF1090)
CF61_RS03780	COG0586	Pfam SNARE associated Golgi protein
CF61_RS03785	COG2186	Transcriptional regulator
CF61_RS03810	COG2271	Major facilitator Superfamily
CF61_RS03820	COG2721	sulfolactate sulfo-lyase activity
CF61_RS03830	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CF61_RS03835	COG0861	Integral membrane protein TerC family
CF61_RS03840	COG0673	inositol 2-dehydrogenase activity
CF61_RS03845	COG2949	membrane
CF61_RS03850	COG1451	nucleotide metabolic process
CF61_RS03865	COG4680	protein conserved in bacteria
CF61_RS03870	COG5499	transcription regulator containing HTH domain
CF61_RS03875	COG0446	pyridine nucleotide-disulphide oxidoreductase
CF61_RS03875	COG1902	pentaerythritol trinitrate reductase activity
CF61_RS03880	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CF61_RS03880	COG3408	Glycogen debranching enzyme
CF61_RS03890	COG0531	amino acid
CF61_RS03895	COG2731	YhcH YjgK YiaL family protein
CF61_RS03900	COG3250	beta-galactosidase activity
CF61_RS03905	COG1609	Transcriptional regulator
CF61_RS03910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CF61_RS03920	COG0840	transmembrane signaling receptor activity
CF61_RS03925	COG1695	Transcriptional regulator
CF61_RS03930	COG2375	cellular response to nickel ion
CF61_RS03945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CF61_RS03950	COG0358	DNA primase activity
CF61_RS03955	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CF61_RS03965	COG0471	metal ion transport
CF61_RS03970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CF61_RS03975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CF61_RS03980	COG0583	DNA-binding transcription factor activity
CF61_RS03990	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CF61_RS04005	COG4991	sh3 domain protein
CF61_RS04015	COG3025	triphosphatase activity
CF61_RS04040	COG2268	Band 7 protein
CF61_RS04045	COG1585	Membrane protein implicated in regulation of membrane protease activity
CF61_RS04055	COG3539	Fimbrial protein
CF61_RS04060	COG3121	Chaperone
CF61_RS04065	COG3188	usher protein
CF61_RS04070	COG3539	Fimbrial protein
CF61_RS04075	COG2960	long-chain fatty acid transporting porin activity
CF61_RS04095	COG3384	dioxygenase
CF61_RS04100	COG0754	glutathionylspermidine amidase activity
CF61_RS04115	COG1538	Outer membrane efflux protein
CF61_RS04120	COG0494	nUDIX hydrolase
CF61_RS04125	COG3151	Protein conserved in bacteria
CF61_RS04130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CF61_RS04135	COG3150	esterase
CF61_RS04140	COG0187	DNA topoisomerase II activity
CF61_RS04145	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CF61_RS04150	COG2249	NAD(P)H dehydrogenase (quinone) activity
CF61_RS04160	COG0642	Histidine kinase
CF61_RS04165	COG0745	RESPONSE REGULATOR receiver
CF61_RS04170	COG3111	PFAM Bacterial OB fold (BOF) protein
CF61_RS04175	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CF61_RS04185	COG2944	sequence-specific DNA binding
CF61_RS04190	COG4166	transmembrane transport
CF61_RS04195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CF61_RS04200	COG0204	Acyl-transferase
CF61_RS04205	COG2132	Multicopper oxidase
CF61_RS04210	COG1032	radical SAM domain protein
CF61_RS04215	COG4238	major outer membrane lipoprotein
CF61_RS04225	COG0656	L-ascorbic acid biosynthetic process
CF61_RS04230	COG1979	alcohol dehydrogenase
CF61_RS04240	COG2207	Transcriptional regulator
CF61_RS04245	COG0586	Pfam SNARE associated Golgi protein
CF61_RS04250	COG0626	cystathionine gamma-synthase activity
CF61_RS04260	COG0811	peptide transport
CF61_RS04265	COG0848	biopolymer transport protein
CF61_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS04280	COG0667	Aldo Keto reductase
CF61_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS04310	COG0667	Aldo Keto reductase
CF61_RS04330	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CF61_RS04335	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS04340	COG5557	Pfam Polysulphide reductase, NrfD
CF61_RS04345	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CF61_RS04350	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CF61_RS04355	COG1773	rubredoxin
CF61_RS04365	COG0298	carbon dioxide binding
CF61_RS04370	COG0625	glutathione transferase activity
CF61_RS04375	COG0754	glutathionylspermidine amidase activity
CF61_RS04380	COG0306	phosphate transporter
CF61_RS04385	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CF61_RS04390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CF61_RS04395	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CF61_RS04400	COG2244	polysaccharide biosynthetic process
CF61_RS04410	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CF61_RS04415	COG0795	lipopolysaccharide-transporting ATPase activity
CF61_RS04425	COG0156	8-amino-7-oxononanoate synthase activity
CF61_RS04430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CF61_RS04440	COG0318	PFAM AMP-dependent synthetase and ligase
CF61_RS04445	COG0456	acetyltransferase
CF61_RS04450	COG2186	Transcriptional regulator
CF61_RS04455	COG0277	FAD linked oxidase domain protein
CF61_RS04460	COG0277	FAD linked oxidase domain protein
CF61_RS04465	COG0247	lactate metabolic process
CF61_RS04470	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CF61_RS04475	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CF61_RS04480	COG1620	l-lactate permease
CF61_RS04515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CF61_RS04520	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CF61_RS04530	COG1811	Na channel or pump
CF61_RS04535	COG1982	Orn Lys Arg decarboxylase major
CF61_RS04540	COG2211	Major facilitator Superfamily
CF61_RS04555	COG1194	a g-specific adenine glycosylase
CF61_RS04565	COG3171	Protein conserved in bacteria
CF61_RS04580	COG0252	asparaginase activity
CF61_RS04590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CF61_RS04605	COG0762	integral membrane protein
CF61_RS04610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CF61_RS04615	COG2805	Type II/IV secretion system protein
CF61_RS04630	COG0189	ligase activity
CF61_RS04635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CF61_RS04640	COG2356	endonuclease I
CF61_RS04650	COG2814	Major facilitator Superfamily
CF61_RS04675	COG1166	arginine decarboxylase activity
CF61_RS04685	COG0501	Belongs to the peptidase M48B family
CF61_RS04690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CF61_RS04695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS04700	COG2213	PTS system mannitol-specific
CF61_RS04705	COG1063	alcohol dehydrogenase
CF61_RS04710	COG1494	fructose-1,6-bisphosphatase
CF61_RS04715	COG3722	fumarate hydratase activity
CF61_RS04720	COG1072	(Pantothenic acid kinase))
CF61_RS04735	COG0191	fructose-bisphosphate aldolase activity
CF61_RS04740	COG0668	transmembrane transport
CF61_RS04745	COG1279	arginine transmembrane transporter activity
CF61_RS04750	COG2968	Membrane
CF61_RS04755	COG0583	DNA-binding transcription factor activity
CF61_RS04760	COG0427	acetyl-CoA hydrolase
CF61_RS04765	COG1024	Enoyl-CoA hydratase
CF61_RS04770	COG1703	isobutyryl-CoA mutase activity
CF61_RS04775	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CF61_RS04775	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CF61_RS04795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CF61_RS04800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CF61_RS04815	COG0006	proline dipeptidase activity
CF61_RS04820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CF61_RS04825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CF61_RS04845	COG2723	6-phospho-beta-galactosidase activity
CF61_RS04855	COG1272	protein, Hemolysin III
CF61_RS04865	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CF61_RS04875	COG0716	FMN binding
CF61_RS04880	COG4974	Belongs to the 'phage' integrase family
CF61_RS04885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CF61_RS04890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CF61_RS04900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CF61_RS04915	COG2233	PERMEase
CF61_RS04925	COG0493	'glutamate synthase
CF61_RS04925	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS04930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS04935	COG2252	PERMEase
CF61_RS04940	COG0402	S-adenosylhomocysteine deaminase activity
CF61_RS04955	COG2233	PERMEase
CF61_RS04960	COG2080	2 iron, 2 sulfur cluster binding
CF61_RS04960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CF61_RS04965	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CF61_RS04970	COG0402	S-adenosylhomocysteine deaminase activity
CF61_RS04975	COG0493	'glutamate synthase
CF61_RS04975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS04980	COG2068	MobA-Related Protein
CF61_RS04985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CF61_RS04995	COG0549	Belongs to the carbamate kinase family
CF61_RS05005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CF61_RS05010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CF61_RS05015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CF61_RS05020	COG3829	transcription factor binding
CF61_RS05025	COG2080	2 iron, 2 sulfur cluster binding
CF61_RS05030	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CF61_RS05035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CF61_RS05040	COG4942	peptidase
CF61_RS05050	COG3387	PFAM Glycoside hydrolase 15-related
CF61_RS05055	COG3387	PFAM Glycoside hydrolase 15-related
CF61_RS05095	COG3710	Transcriptional regulator
CF61_RS05100	COG2771	luxR family
CF61_RS05105	COG0814	amino acid
CF61_RS05110	COG0183	Belongs to the thiolase family
CF61_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS05125	COG2814	Major facilitator Superfamily
CF61_RS05130	COG1794	racemase activity, acting on amino acids and derivatives
CF61_RS05135	COG0583	DNA-binding transcription factor activity
CF61_RS05145	COG1609	Transcriptional regulator
CF61_RS05160	COG0667	Aldo Keto reductase
CF61_RS05170	COG0861	Integral membrane protein TerC family
CF61_RS05195	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CF61_RS05210	COG2165	general secretion pathway protein
CF61_RS05215	COG4795	General secretion pathway protein
CF61_RS05225	COG4967	type IV pilus modification protein PilV
CF61_RS05230	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CF61_RS05240	COG1074	ATP-dependent DNA helicase activity
CF61_RS05245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CF61_RS05250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CF61_RS05250	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CF61_RS05255	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF61_RS05275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CF61_RS05280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CF61_RS05285	COG2166	iron-sulfur cluster assembly
CF61_RS05290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CF61_RS05300	COG0583	DNA-binding transcription factor activity
CF61_RS05305	COG2363	Small membrane protein
CF61_RS05315	COG1349	DNA-binding transcription factor activity
CF61_RS05325	COG1070	Carbohydrate kinase
CF61_RS05335	COG0738	Major facilitator superfamily
CF61_RS05340	COG0235	Class ii aldolase
CF61_RS05345	COG1454	alcohol dehydrogenase
CF61_RS05355	COG1760	l-serine dehydratase
CF61_RS05360	COG0814	amino acid
CF61_RS05365	COG1611	Belongs to the LOG family
CF61_RS05385	COG3098	single-species biofilm formation
CF61_RS05390	COG0564	pseudouridine synthase activity
CF61_RS05395	COG0716	FMN binding
CF61_RS05400	COG2271	Major facilitator Superfamily
CF61_RS05405	COG4948	Mandelate Racemase Muconate Lactonizing
CF61_RS05410	COG4999	Histidine kinase
CF61_RS05410	COG2205	protein histidine kinase activity
CF61_RS05410	COG3850	Histidine kinase
CF61_RS05410	COG3437	response regulator, receiver
CF61_RS05415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CF61_RS05420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CF61_RS05425	COG2336	PFAM SpoVT AbrB
CF61_RS05430	COG2337	Toxic component of a toxin-antitoxin (TA) module
CF61_RS05435	COG3956	TIGRFAM MazG family protein
CF61_RS05450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CF61_RS05460	COG0602	queuosine metabolic process
CF61_RS05465	COG1070	Carbohydrate kinase
CF61_RS05470	COG2223	nitrite transmembrane transporter activity
CF61_RS05475	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS05480	COG0277	FAD linked oxidase domain protein
CF61_RS05485	COG0477	Major facilitator Superfamily
CF61_RS05490	COG2086	electron transfer activity
CF61_RS05495	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CF61_RS05500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CF61_RS05505	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CF61_RS05510	COG0644	oxidoreductase
CF61_RS05515	COG0720	synthase
CF61_RS05535	COG1203	CRISPR-associated helicase, Cas3
CF61_RS05545	COG2801	Transposase and inactivated derivatives
CF61_RS05550	COG1203	CRISPR-associated helicase, Cas3
CF61_RS05565	COG1857	crispr-associated protein
CF61_RS05580	COG1518	maintenance of DNA repeat elements
CF61_RS05585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CF61_RS05590	COG2234	aminopeptidase activity
CF61_RS05645	COG1388	LysM domain
CF61_RS05645	COG4942	peptidase
CF61_RS05650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CF61_RS05655	COG2610	gluconate transmembrane transporter activity
CF61_RS05660	COG3622	Belongs to the hyi family
CF61_RS05665	COG0235	Class ii aldolase
CF61_RS05670	COG3395	kinase activity
CF61_RS05675	COG2084	Dehydrogenase
CF61_RS05680	COG1349	DNA-binding transcription factor activity
CF61_RS05685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CF61_RS05705	COG3604	Transcriptional regulator
CF61_RS05710	COG0309	Hydrogenase expression formation protein (HypE)
CF61_RS05715	COG0409	Hydrogenase expression formation protein
CF61_RS05720	COG0298	carbon dioxide binding
CF61_RS05725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CF61_RS05730	COG0375	protein maturation
CF61_RS05745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS05750	COG0651	ATP synthesis coupled electron transport
CF61_RS05755	COG0650	Formate hydrogenlyase subunit 4
CF61_RS05760	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CF61_RS05760	COG3261	NADH dehydrogenase
CF61_RS05765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CF61_RS05770	COG3260	NADH ubiquinone oxidoreductase 20
CF61_RS05780	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CF61_RS05785	COG2723	6-phospho-beta-galactosidase activity
CF61_RS05790	COG1263	PTS System
CF61_RS05790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS05795	COG1609	Transcriptional regulator
CF61_RS05800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS05805	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CF61_RS05825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CF61_RS05825	COG0517	IMP dehydrogenase activity
CF61_RS05830	COG1349	DNA-binding transcription factor activity
CF61_RS05835	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS05845	COG3731	PTS system glucitol sorbitol-specific IIA component
CF61_RS05850	COG3732	PTS system glucitol sorbitol-specific
CF61_RS05855	COG3730	PTS system glucitol sorbitol-specific
CF61_RS05860	COG2951	lytic endotransglycosylase activity
CF61_RS05865	COG1546	Belongs to the CinA family
CF61_RS05890	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CF61_RS05920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF61_RS05925	COG1238	metal cluster binding
CF61_RS05940	COG2814	Major facilitator Superfamily
CF61_RS05945	COG1566	PFAM secretion protein HlyD family protein
CF61_RS05950	COG1846	Transcriptional regulator
CF61_RS05960	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CF61_RS05965	COG2814	Major facilitator Superfamily
CF61_RS05970	COG2113	Glycine betaine
CF61_RS05975	COG4176	ABC-type proline glycine betaine transport system permease component
CF61_RS05980	COG4175	Glycine betaine
CF61_RS05985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF61_RS05990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF61_RS06000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CF61_RS06005	COG4575	ribosome binding
CF61_RS06020	COG2916	Histone family protein nucleoid-structuring protein H-NS
CF61_RS06025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF61_RS06030	COG0640	Transcriptional regulator
CF61_RS06035	COG0401	homolog of Blt101
CF61_RS06040	COG1652	LysM domain
CF61_RS06045	COG1802	Transcriptional regulator
CF61_RS06050	COG1113	amino acid transport
CF61_RS06055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CF61_RS06060	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS06065	COG0579	oxidoreductase
CF61_RS06075	COG0366	Alpha amylase catalytic
CF61_RS06080	COG0366	Alpha amylase catalytic
CF61_RS06090	COG1662	PFAM IS1 transposase
CF61_RS06095	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CF61_RS06105	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CF61_RS06115	COG1475	DNA binding
CF61_RS06125	COG0582	viral genome integration into host DNA
CF61_RS06135	COG2867	negative regulation of translational initiation
CF61_RS06145	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF61_RS06150	COG0497	DNA recombination
CF61_RS06170	COG4536	flavin adenine dinucleotide binding
CF61_RS06175	COG4137	Cytochrome C assembly protein
CF61_RS06180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CF61_RS06205	COG2885	chlorophyll binding
CF61_RS06210	COG2199	diguanylate cyclase activity
CF61_RS06225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CF61_RS06230	COG1605	Chorismate mutase
CF61_RS06230	COG0287	Prephenate dehydrogenase
CF61_RS06235	COG1605	Chorismate mutase
CF61_RS06235	COG0077	Prephenate dehydratase
CF61_RS06240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CF61_RS06250	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF61_RS06255	COG0564	pseudouridine synthase activity
CF61_RS06260	COG1496	oxidoreductase activity
CF61_RS06265	COG0542	response to heat
CF61_RS06295	COG0477	Major facilitator Superfamily
CF61_RS06300	COG5544	Lipoprotein
CF61_RS06305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CF61_RS06310	COG0045	succinate-CoA ligase (ADP-forming) activity
CF61_RS06310	COG1042	CoA-binding domain protein
CF61_RS06310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF61_RS06315	COG3148	PFAM DTW domain containing protein
CF61_RS06320	COG3118	belongs to the thioredoxin family
CF61_RS06330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CF61_RS06350	COG0583	DNA-binding transcription factor activity
CF61_RS06360	COG0513	Belongs to the DEAD box helicase family
CF61_RS06370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CF61_RS06380	COG1595	DNA-templated transcription, initiation
CF61_RS06385	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CF61_RS06390	COG3026	antisigma factor binding
CF61_RS06395	COG3086	response to oxidative stress
CF61_RS06405	COG0681	Belongs to the peptidase S26 family
CF61_RS06425	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CF61_RS06450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS06455	COG1737	Transcriptional regulator
CF61_RS06460	COG0560	Phosphoserine phosphatase
CF61_RS06480	COG2205	protein histidine kinase activity
CF61_RS06485	COG3170	Tfp pilus assembly protein FimV
CF61_RS06490	COG2204	response regulator
CF61_RS06495	COG0347	Belongs to the P(II) protein family
CF61_RS06500	COG1017	nitric oxide dioxygenase activity
CF61_RS06500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF61_RS06510	COG1940	carbohydrate kinase activity
CF61_RS06515	COG0457	Tetratricopeptide repeat
CF61_RS06520	COG1879	ABC-type sugar transport system periplasmic component
CF61_RS06525	COG1129	ABC transporter
CF61_RS06530	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF61_RS06535	COG1063	alcohol dehydrogenase
CF61_RS06540	COG2017	converts alpha-aldose to the beta-anomer
CF61_RS06545	COG2259	Doxx family
CF61_RS06570	COG4638	Rieske (2fe-2S)
CF61_RS06575	COG0583	DNA-binding transcription factor activity
CF61_RS06580	COG2814	Major facilitator Superfamily
CF61_RS06585	COG3711	transcriptional antiterminator
CF61_RS06590	COG1073	alpha beta
CF61_RS06595	COG0483	inositol monophosphate 1-phosphatase activity
CF61_RS06615	COG0822	iron-sulfur transferase activity
CF61_RS06635	COG0633	Ferredoxin
CF61_RS06640	COG2975	iron-sulfur cluster assembly
CF61_RS06655	COG2897	thiosulfate sulfurtransferase activity
CF61_RS06660	COG2373	Large extracellular alpha-helical protein
CF61_RS06665	COG4953	penicillin-binding protein 1C
CF61_RS06695	COG2976	Protein conserved in bacteria
CF61_RS06710	COG1645	bacterial-type flagellum-dependent swarming motility
CF61_RS06720	COG0516	GMP reductase activity
CF61_RS06720	COG0517	IMP dehydrogenase activity
CF61_RS06735	COG3133	Outer membrane lipoprotein
CF61_RS06750	COG2200	EAL domain
CF61_RS06755	COG0248	Ppx GppA phosphatase
CF61_RS06760	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CF61_RS06765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CF61_RS06780	COG2233	PERMEase
CF61_RS06790	COG1393	Belongs to the ArsC family
CF61_RS06795	COG4783	chaperone-mediated protein folding
CF61_RS06800	COG0628	permease
CF61_RS06805	COG2116	formate transmembrane transporter activity
CF61_RS06810	COG3604	Transcriptional regulator
CF61_RS06820	COG3260	NADH ubiquinone oxidoreductase 20
CF61_RS06825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CF61_RS06830	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CF61_RS06830	COG3261	NADH dehydrogenase
CF61_RS06835	COG0651	ATP synthesis coupled electron transport
CF61_RS06840	COG4237	Hydrogenase 4 membrane
CF61_RS06845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CF61_RS06850	COG0650	Formate hydrogenlyase subunit 4
CF61_RS06855	COG0651	ATP synthesis coupled electron transport
CF61_RS06860	COG0651	ATP synthesis coupled electron transport
CF61_RS06865	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS06870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CF61_RS06875	COG2716	regulation of RNA biosynthetic process
CF61_RS06885	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CF61_RS06900	COG2321	neutral zinc metallopeptidase
CF61_RS06910	COG0400	carboxylic ester hydrolase activity
CF61_RS06925	COG1393	Belongs to the ArsC family
CF61_RS06935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF61_RS06940	COG3850	Histidine kinase
CF61_RS06945	COG0493	'glutamate synthase
CF61_RS06945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS06955	COG5342	invasion associated locus B
CF61_RS06960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CF61_RS06965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CF61_RS06970	COG0280	phosphate acetyltransferase
CF61_RS06970	COG0281	malic enzyme
CF61_RS06975	COG4810	utilization protein
CF61_RS06980	COG4917	ethanolamine utilization protein
CF61_RS06985	COG4766	ethanolamine catabolic process
CF61_RS06990	COG4812	Cobalamin adenosyltransferase
CF61_RS06995	COG0280	phosphate acetyltransferase
CF61_RS07000	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CF61_RS07005	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CF61_RS07010	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS07015	COG4820	ethanolamine utilization protein (EutJ)
CF61_RS07020	COG1454	alcohol dehydrogenase
CF61_RS07025	COG3192	ethanolamine utilization protein
CF61_RS07030	COG4819	ethanolamine utilization protein
CF61_RS07035	COG4303	Ethanolamine ammonia lyase large subunit
CF61_RS07050	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CF61_RS07055	COG4303	Ethanolamine ammonia lyase large subunit
CF61_RS07065	COG4816	utilization protein
CF61_RS07070	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CF61_RS07075	COG2207	Transcriptional regulator
CF61_RS07085	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF61_RS07090	COG0456	acetyltransferase
CF61_RS07105	COG2837	iron assimilation
CF61_RS07110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF61_RS07115	COG1263	PTS System
CF61_RS07115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS07130	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS07135	COG4150	thiosulfate binding
CF61_RS07140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CF61_RS07145	COG4208	sulfate ABC transporter
CF61_RS07150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CF61_RS07155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CF61_RS07160	COG4884	unkown
CF61_RS07160	COG3831	ATPase activity
CF61_RS07175	COG2190	(PTS) system
CF61_RS07180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF61_RS07185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS07190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CF61_RS07210	COG3530	Putative quorum-sensing-regulated virulence factor
CF61_RS07215	COG0385	Bile acid
CF61_RS07220	COG0583	DNA-binding transcription factor activity
CF61_RS07230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CF61_RS07235	COG2211	Major facilitator Superfamily
CF61_RS07245	COG0583	DNA-binding transcription factor activity
CF61_RS07275	COG3415	Transposase
CF61_RS07280	COG3415	Transposase
CF61_RS07295	COG2199	diguanylate cyclase activity
CF61_RS07295	COG2200	EAL domain
CF61_RS07300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CF61_RS07330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS07335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS07340	COG0006	proline dipeptidase activity
CF61_RS07345	COG1363	Peptidase, m42
CF61_RS07350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS07350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS07350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF61_RS07355	COG2207	Transcriptional regulator
CF61_RS07360	COG3279	Response regulator of the LytR AlgR family
CF61_RS07365	COG3275	phosphorelay sensor kinase activity
CF61_RS07370	COG0436	Aminotransferase
CF61_RS07375	COG1560	Kdo2-lipid A biosynthetic process
CF61_RS07405	COG0028	Belongs to the TPP enzyme family
CF61_RS07410	COG0679	Auxin Efflux Carrier
CF61_RS07415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CF61_RS07420	COG2205	protein histidine kinase activity
CF61_RS07420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF61_RS07420	COG0784	Response regulator, receiver
CF61_RS07420	COG2198	Histidine kinase
CF61_RS07425	COG2197	response regulator
CF61_RS07430	COG1566	PFAM secretion protein HlyD family protein
CF61_RS07435	COG0477	Major facilitator Superfamily
CF61_RS07445	COG2610	gluconate transmembrane transporter activity
CF61_RS07450	COG0583	DNA-binding transcription factor activity
CF61_RS07630	COG3772	lysozyme
CF61_RS07650	COG1783	phage Terminase large subunit
CF61_RS07655	COG3567	Phage-associated protein, HI1409 family
CF61_RS07810	COG0582	viral genome integration into host DNA
CF61_RS07820	COG2116	formate transmembrane transporter activity
CF61_RS07825	COG2853	Lipoprotein
CF61_RS07835	COG2067	long-chain fatty acid transport protein
CF61_RS07840	COG3691	Protein conserved in bacteria
CF61_RS07855	COG2062	phosphohistidine phosphatase, SixA
CF61_RS07860	COG3539	Fimbrial protein
CF61_RS07865	COG3188	usher protein
CF61_RS07870	COG3121	Chaperone
CF61_RS07875	COG3539	Fimbrial protein
CF61_RS07880	COG3539	Fimbrial protein
CF61_RS07885	COG3539	Fimbrial protein
CF61_RS07915	COG0730	response to heat
CF61_RS07920	COG3101	peptidyl-lysine hydroxylation
CF61_RS07935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CF61_RS07940	COG2814	Major facilitator Superfamily
CF61_RS07955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CF61_RS07965	COG0586	Pfam SNARE associated Golgi protein
CF61_RS07975	COG0285	dihydrofolate synthase activity
CF61_RS07980	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CF61_RS07985	COG1286	toxin biosynthetic process
CF61_RS07990	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CF61_RS07995	COG0163	prenyltransferase activity
CF61_RS08000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF61_RS08005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF61_RS08010	COG4215	(ABC) transporter
CF61_RS08015	COG4160	amino acid transport
CF61_RS08020	COG4598	ABC transporter
CF61_RS08030	COG1090	epimerase
CF61_RS08035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CF61_RS08040	COG0625	glutathione transferase activity
CF61_RS08045	COG0625	glutathione transferase activity
CF61_RS08050	COG0622	Phosphoesterase
CF61_RS08055	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CF61_RS08060	COG1288	antiporter activity
CF61_RS08065	COG0857	belongs to the CobB CobQ family
CF61_RS08065	COG0280	phosphate acetyltransferase
CF61_RS08070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CF61_RS08090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF61_RS08095	COG0471	metal ion transport
CF61_RS08095	COG0490	domain, Protein
CF61_RS08105	COG0436	Aminotransferase
CF61_RS08110	COG0583	DNA-binding transcription factor activity
CF61_RS08130	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CF61_RS08135	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CF61_RS08155	COG0839	Belongs to the complex I subunit 6 family
CF61_RS08165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CF61_RS08170	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CF61_RS08185	COG2234	aminopeptidase activity
CF61_RS08200	COG2153	protein acetylation
CF61_RS08205	COG4575	ribosome binding
CF61_RS08210	COG1169	isochorismate synthase
CF61_RS08225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CF61_RS08235	COG0318	PFAM AMP-dependent synthetase and ligase
CF61_RS08300	COG1414	Transcriptional regulator
CF61_RS08320	COG5464	transposase or invertase
CF61_RS08325	COG0247	lactate metabolic process
CF61_RS08335	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CF61_RS08340	COG2271	Major facilitator Superfamily
CF61_RS08345	COG0584	glycerophosphoryl diester phosphodiesterase
CF61_RS08350	COG0583	DNA-binding transcription factor activity
CF61_RS08355	COG3642	lipopolysaccharide core region biosynthetic process
CF61_RS08360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF61_RS08365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF61_RS08370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CF61_RS08380	COG3468	outer membrane autotransporter barrel domain protein
CF61_RS08390	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CF61_RS08395	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CF61_RS08400	COG3234	Protein of unknown function (DUF1175)
CF61_RS08405	COG2373	Large extracellular alpha-helical protein
CF61_RS08410	COG5445	Predicted secreted protein (DUF2300)
CF61_RS08415	COG4676	Protein conserved in bacteria
CF61_RS08420	COG0784	Response regulator, receiver
CF61_RS08420	COG2205	protein histidine kinase activity
CF61_RS08425	COG2197	response regulator
CF61_RS08430	COG0642	Histidine kinase
CF61_RS08430	COG2198	Histidine kinase
CF61_RS08445	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF61_RS08450	COG1477	protein flavinylation
CF61_RS08455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CF61_RS08455	COG2169	Transcriptional regulator
CF61_RS08460	COG3145	DNA-N1-methyladenine dioxygenase activity
CF61_RS08465	COG4615	Cyclic peptide transporter
CF61_RS08485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS08485	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CF61_RS08490	COG3062	negative regulation of establishment of protein localization
CF61_RS08500	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS08505	COG0348	domain, Protein
CF61_RS08510	COG3043	anaerobic respiration
CF61_RS08515	COG3005	denitrification pathway
CF61_RS08525	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CF61_RS08530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CF61_RS08535	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CF61_RS08545	COG1138	Cytochrome C-type biogenesis protein
CF61_RS08550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CF61_RS08555	COG3088	subunit of a heme lyase
CF61_RS08555	COG4235	cytochrome complex assembly
CF61_RS08560	COG2197	response regulator
CF61_RS08580	COG3083	sulfuric ester hydrolase activity
CF61_RS08600	COG1061	Type III restriction enzyme res subunit
CF61_RS08605	COG1187	pseudouridine synthase activity
CF61_RS08610	COG2814	Major facilitator Superfamily
CF61_RS08620	COG4172	Belongs to the ABC transporter superfamily
CF61_RS08625	COG4239	(ABC) transporter, permease
CF61_RS08630	COG4174	ABC transporter (Permease)
CF61_RS08635	COG4166	transmembrane transport
CF61_RS08640	COG2200	EAL domain
CF61_RS08645	COG0791	NLP P60 protein
CF61_RS08650	COG0671	phosphoesterase, PA-phosphatase related
CF61_RS08655	COG0523	cobalamin synthesis protein
CF61_RS08660	COG0246	Mannitol dehydrogenase
CF61_RS08675	COG2814	Major facilitator Superfamily
CF61_RS08680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS08680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS08685	COG1105	Belongs to the carbohydrate kinase PfkB family
CF61_RS08690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS08690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS08690	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CF61_RS08695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF61_RS08700	COG2313	pseudouridylate synthase activity
CF61_RS08705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CF61_RS08710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF61_RS08720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CF61_RS08725	COG1522	sequence-specific DNA binding
CF61_RS08725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF61_RS08735	COG2855	membrane
CF61_RS08740	COG0583	DNA-binding transcription factor activity
CF61_RS08745	COG0833	amino acid
CF61_RS08750	COG4771	TonB-dependent receptor
CF61_RS08770	COG2311	Membrane
CF61_RS08780	COG1609	Transcriptional regulator
CF61_RS08785	COG1879	ABC-type sugar transport system periplasmic component
CF61_RS08790	COG1129	ABC transporter
CF61_RS08795	COG4211	Belongs to the binding-protein-dependent transport system permease family
CF61_RS08800	COG0167	dihydroorotate dehydrogenase activity
CF61_RS08800	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CF61_RS08805	COG0493	'glutamate synthase
CF61_RS08815	COG2949	membrane
CF61_RS08825	COG1346	cytolysis
CF61_RS08835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CF61_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS08855	COG0586	Pfam SNARE associated Golgi protein
CF61_RS08865	COG1686	Belongs to the peptidase S11 family
CF61_RS08870	COG0277	FAD linked oxidase domain protein
CF61_RS08875	COG1472	Belongs to the glycosyl hydrolase 3 family
CF61_RS08880	COG1732	Glycine betaine
CF61_RS08885	COG1174	glycine betaine transport
CF61_RS08890	COG1125	glycine betaine transport
CF61_RS08895	COG1174	glycine betaine transport
CF61_RS08905	COG0789	Transcriptional regulator
CF61_RS08910	COG3275	phosphorelay sensor kinase activity
CF61_RS08915	COG3279	Response regulator of the LytR AlgR family
CF61_RS08920	COG4807	Protein conserved in bacteria
CF61_RS08925	COG4808	Protein conserved in bacteria
CF61_RS08930	COG4715	Zinc finger, swim domain protein
CF61_RS08935	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CF61_RS08940	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CF61_RS08945	COG0714	Associated with various cellular activities
CF61_RS08955	COG3831	ATPase activity
CF61_RS08960	COG3831	ATPase activity
CF61_RS08970	COG0489	protein tyrosine kinase activity
CF61_RS08985	COG3539	Fimbrial protein
CF61_RS08995	COG3121	Chaperone
CF61_RS09000	COG3188	usher protein
CF61_RS09005	COG3539	Fimbrial protein
CF61_RS09010	COG5455	response to cobalt ion
CF61_RS09015	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CF61_RS09030	COG0351	phosphomethylpyrimidine kinase
CF61_RS09035	COG3757	hydrolase, family 25
CF61_RS09040	COG2188	Transcriptional regulator
CF61_RS09045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF61_RS09050	COG1397	ADP-ribosylglycohydrolase
CF61_RS09055	COG2211	Major facilitator Superfamily
CF61_RS09060	COG1830	Aldolase
CF61_RS09075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS09085	COG3775	system Galactitol-specific IIC component
CF61_RS09090	COG1063	alcohol dehydrogenase
CF61_RS09095	COG1662	PFAM IS1 transposase
CF61_RS09100	COG1063	alcohol dehydrogenase
CF61_RS09125	COG0826	peptidase U32
CF61_RS09140	COG0745	RESPONSE REGULATOR receiver
CF61_RS09145	COG2205	protein histidine kinase activity
CF61_RS09170	COG4245	von Willebrand factor, type A
CF61_RS09180	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CF61_RS09185	COG0443	Heat shock 70 kDa protein
CF61_RS09190	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CF61_RS09195	COG5001	Diguanylate cyclase
CF61_RS09195	COG5002	protein histidine kinase activity
CF61_RS09195	COG3447	MASE1 domain protein
CF61_RS09200	COG0572	uridine kinase
CF61_RS09210	COG2982	Protein involved in outer membrane biogenesis
CF61_RS09225	COG1253	flavin adenine dinucleotide binding
CF61_RS09250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CF61_RS09330	COG0438	transferase activity, transferring glycosyl groups
CF61_RS09340	COG0140	phosphoribosyl-ATP diphosphatase activity
CF61_RS09340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CF61_RS09355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CF61_RS09360	COG0131	Imidazoleglycerol-phosphate dehydratase
CF61_RS09360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CF61_RS09380	COG2161	toxin-antitoxin pair type II binding
CF61_RS09385	COG4115	mRNA cleavage
CF61_RS09390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF61_RS09395	COG0583	DNA-binding transcription factor activity
CF61_RS09400	COG0531	amino acid
CF61_RS09405	COG2391	methyltransferase activity
CF61_RS09410	COG0425	Belongs to the sulfur carrier protein TusA family
CF61_RS09415	COG2925	Exonuclease
CF61_RS09420	COG1686	Belongs to the peptidase S11 family
CF61_RS09430	COG1289	transmembrane transporter activity
CF61_RS09440	COG4917	ethanolamine utilization protein
CF61_RS09480	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CF61_RS09495	COG1376	ErfK ybiS ycfS ynhG family protein
CF61_RS09505	COG0583	DNA-binding transcription factor activity
CF61_RS09510	COG0583	DNA-binding transcription factor activity
CF61_RS09535	COG0217	transcriptional regulatory protein
CF61_RS09540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CF61_RS09545	COG0477	Major facilitator Superfamily
CF61_RS09555	COG1388	LysM domain
CF61_RS09555	COG4932	domain protein
CF61_RS09555	COG2373	Large extracellular alpha-helical protein
CF61_RS09580	COG3038	cytochrome b561
CF61_RS09585	COG3443	Belongs to the bacterial solute-binding protein 9 family
CF61_RS09600	COG2351	hydroxyisourate hydrolase activity
CF61_RS09605	COG0745	RESPONSE REGULATOR receiver
CF61_RS09610	COG2205	protein histidine kinase activity
CF61_RS09625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF61_RS09640	COG1418	mRNA catabolic process
CF61_RS09645	COG0270	DNA (cytosine-5-)-methyltransferase activity
CF61_RS09650	COG3727	T/G mismatch-specific endonuclease activity
CF61_RS09655	COG0697	spore germination
CF61_RS09660	COG2354	Protein conserved in bacteria
CF61_RS09665	COG5475	Uncharacterized small protein (DUF2158)
CF61_RS09695	COG1662	PFAM IS1 transposase
CF61_RS09710	COG2076	Multidrug Resistance protein
CF61_RS09715	COG1881	PFAM PEBP family protein
CF61_RS09720	COG2207	Transcriptional regulator
CF61_RS09735	COG0675	Transposase, IS605 OrfB family
CF61_RS09740	COG2135	peptidase activity
CF61_RS09745	COG0425	Belongs to the sulfur carrier protein TusA family
CF61_RS09750	COG2391	methyltransferase activity
CF61_RS09760	COG0366	Alpha amylase catalytic
CF61_RS09770	COG1516	flagellar protein fliS
CF61_RS09775	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CF61_RS09785	COG1191	sigma factor activity
CF61_RS09795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF61_RS09805	COG0765	amino acid transport
CF61_RS09810	COG1126	abc transporter atp-binding protein
CF61_RS09815	COG2197	response regulator
CF61_RS09830	COG2197	response regulator
CF61_RS09860	COG3318	Belongs to the UPF0149 family
CF61_RS09860	COG3012	SEC-C Motif Domain Protein
CF61_RS09865	COG0814	amino acid
CF61_RS09875	COG1528	Iron-storage protein
CF61_RS09895	COG1528	Iron-storage protein
CF61_RS09900	COG1879	ABC-type sugar transport system periplasmic component
CF61_RS09905	COG1129	ABC transporter
CF61_RS09910	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF61_RS09915	COG1877	trehalose-phosphatase activity
CF61_RS09925	COG0589	response to stress
CF61_RS09940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CF61_RS09945	COG1360	Flagellar Motor Protein
CF61_RS09950	COG0643	Histidine kinase
CF61_RS09950	COG2198	Histidine kinase
CF61_RS09960	COG0840	transmembrane signaling receptor activity
CF61_RS09970	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CF61_RS09980	COG0745	RESPONSE REGULATOR receiver
CF61_RS09985	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CF61_RS09995	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CF61_RS10005	COG3755	Protein conserved in bacteria
CF61_RS10015	COG3102	Protein conserved in bacteria
CF61_RS10025	COG3005	denitrification pathway
CF61_RS10030	COG0243	molybdopterin cofactor binding
CF61_RS10045	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CF61_RS10050	COG1801	Protein of unknown function DUF72
CF61_RS10130	COG1335	isochorismatase
CF61_RS10140	COG0494	nUDIX hydrolase
CF61_RS10145	COG0217	transcriptional regulatory protein
CF61_RS10170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CF61_RS10180	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CF61_RS10185	COG0739	heme binding
CF61_RS10190	COG1560	Kdo2-lipid A biosynthetic process
CF61_RS10195	COG0469	pyruvate kinase activity
CF61_RS10200	COG1737	Transcriptional regulator
CF61_RS10210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CF61_RS10215	COG0129	dihydroxy-acid dehydratase activity
CF61_RS10220	COG0800	Aldolase
CF61_RS10230	COG3141	response to X-ray
CF61_RS10245	COG2979	Protein of unknown function (DUF533)
CF61_RS10250	COG1770	oligopeptidase
CF61_RS10255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CF61_RS10260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CF61_RS10270	COG2372	response to copper ion
CF61_RS10275	COG1276	copper resistance
CF61_RS10290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CF61_RS10310	COG3008	intermembrane lipid transfer
CF61_RS10315	COG2995	paraquat-inducible protein a
CF61_RS10320	COG1956	GAF domain-containing protein
CF61_RS10330	COG0793	Belongs to the peptidase S41A family
CF61_RS10340	COG2814	Major facilitator Superfamily
CF61_RS10345	COG1414	Transcriptional regulator
CF61_RS10380	COG2226	methyltransferase
CF61_RS10400	COG3716	PTS system mannose fructose sorbose family IID component
CF61_RS10405	COG3715	PTS system
CF61_RS10410	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS10410	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS10420	COG1253	flavin adenine dinucleotide binding
CF61_RS10425	COG2200	EAL domain
CF61_RS10430	COG1760	l-serine dehydratase
CF61_RS10440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CF61_RS10460	COG0251	oxidation-reduction process
CF61_RS10465	COG1199	ATP-dependent helicase activity
CF61_RS10470	COG1214	PFAM Peptidase M22, glycoprotease
CF61_RS10475	COG3065	identical protein binding
CF61_RS10480	COG0318	PFAM AMP-dependent synthetase and ligase
CF61_RS10485	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CF61_RS10490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF61_RS10495	COG4638	Rieske (2fe-2S)
CF61_RS10500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CF61_RS10505	COG0473	3-isopropylmalate dehydrogenase activity
CF61_RS10510	COG0583	DNA-binding transcription factor activity
CF61_RS10520	COG3615	Tellurite resistance protein tehB
CF61_RS10530	COG2261	transglycosylase associated protein
CF61_RS10540	COG2199	diguanylate cyclase activity
CF61_RS10540	COG2203	Gaf domain
CF61_RS10545	COG3042	response to heat
CF61_RS10550	COG3189	MarR family transcriptional regulator
CF61_RS10555	COG2807	transmembrane transport
CF61_RS10560	COG2207	Transcriptional regulator
CF61_RS10575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CF61_RS10580	COG2199	diguanylate cyclase activity
CF61_RS10585	COG2199	diguanylate cyclase activity
CF61_RS10595	COG2766	serine protein kinase
CF61_RS10600	COG3713	MltA-interacting MipA family protein
CF61_RS10605	COG0656	L-ascorbic acid biosynthetic process
CF61_RS10610	COG0676	glucose-6-phosphate 1-epimerase activity
CF61_RS10615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CF61_RS10625	COG3139	Protein of unknown function (DUF1315)
CF61_RS10630	COG1063	alcohol dehydrogenase
CF61_RS10635	COG2271	Major facilitator Superfamily
CF61_RS10640	COG1662	PFAM IS1 transposase
CF61_RS10645	COG0667	Aldo Keto reductase
CF61_RS10650	COG1349	DNA-binding transcription factor activity
CF61_RS10655	COG2814	Major facilitator Superfamily
CF61_RS10660	COG1335	isochorismatase
CF61_RS10665	COG0252	asparaginase activity
CF61_RS10670	COG0616	signal peptide processing
CF61_RS10680	COG0778	Nitroreductase
CF61_RS10695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CF61_RS10700	COG0443	Heat shock 70 kDa protein
CF61_RS10705	COG0484	heat shock protein binding
CF61_RS10710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CF61_RS10720	COG0494	nUDIX hydrolase
CF61_RS10725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CF61_RS10730	COG2897	thiosulfate sulfurtransferase activity
CF61_RS10735	COG4136	ATPase activity
CF61_RS10740	COG4135	transport system, permease component
CF61_RS10745	COG4134	Bacterial extracellular solute-binding protein
CF61_RS10750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CF61_RS10755	COG0398	Pfam SNARE associated Golgi protein
CF61_RS10765	COG0398	Pfam SNARE associated Golgi protein
CF61_RS10770	COG0708	Exodeoxyribonuclease III
CF61_RS10800	COG3678	ATP-independent chaperone mediated protein folding
CF61_RS10810	COG0322	excinuclease ABC activity
CF61_RS10825	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF61_RS10830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF61_RS10835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CF61_RS10840	COG1447	Phosphotransferase system cellobiose-specific component IIA
CF61_RS10845	COG2169	Transcriptional regulator
CF61_RS10845	COG1917	Cupin 2, conserved barrel domain protein
CF61_RS10850	COG1486	melibiose metabolic process
CF61_RS10860	COG0753	catalase activity
CF61_RS10885	COG1823	symporter activity
CF61_RS10890	COG1988	membrane-bound metal-dependent
CF61_RS10895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF61_RS10905	COG3001	Fructosamine kinase
CF61_RS10915	COG1105	Belongs to the carbohydrate kinase PfkB family
CF61_RS10920	COG3137	Salt-induced outer membrane protein
CF61_RS10935	COG1662	PFAM IS1 transposase
CF61_RS10990	COG0386	Belongs to the glutathione peroxidase family
CF61_RS11000	COG0791	NLP P60 protein
CF61_RS11005	COG2200	EAL domain
CF61_RS11015	COG4256	Hemin uptake protein
CF61_RS11020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CF61_RS11035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF61_RS11035	COG0574	Belongs to the PEP-utilizing enzyme family
CF61_RS11040	COG0318	PFAM AMP-dependent synthetase and ligase
CF61_RS11045	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CF61_RS11050	COG0644	oxidoreductase
CF61_RS11055	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CF61_RS11060	COG2086	electron transfer activity
CF61_RS11070	COG1917	Cupin 2, conserved barrel domain protein
CF61_RS11070	COG2207	Transcriptional regulator
CF61_RS11075	COG1960	acyl-CoA dehydrogenase activity
CF61_RS11080	COG4670	ketone body catabolic process
CF61_RS11095	COG2271	Major facilitator Superfamily
CF61_RS11100	COG0738	Major facilitator superfamily
CF61_RS11110	COG0628	permease
CF61_RS11115	COG0247	lactate metabolic process
CF61_RS11115	COG0277	FAD linked oxidase domain protein
CF61_RS11120	COG2050	protein possibly involved in aromatic compounds catabolism
CF61_RS11130	COG0316	Belongs to the HesB IscA family
CF61_RS11135	COG0719	Fe-S assembly protein
CF61_RS11140	COG0396	ATPase activity
CF61_RS11145	COG0719	Fe-S assembly protein
CF61_RS11160	COG1376	ErfK ybiS ycfS ynhG family protein
CF61_RS11165	COG4238	major outer membrane lipoprotein
CF61_RS11170	COG0469	pyruvate kinase activity
CF61_RS11180	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS11185	COG2414	aldehyde ferredoxin oxidoreductase
CF61_RS11195	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS11200	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CF61_RS11210	COG4529	Protein conserved in bacteria
CF61_RS11230	COG3468	outer membrane autotransporter barrel domain protein
CF61_RS11240	COG0307	riboflavin synthase, alpha
CF61_RS11245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CF61_RS11250	COG2814	Major facilitator Superfamily
CF61_RS11255	COG0583	DNA-binding transcription factor activity
CF61_RS11270	COG2814	Major facilitator Superfamily
CF61_RS11275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CF61_RS11280	COG0791	NLP P60 protein
CF61_RS11285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CF61_RS11290	COG1201	RNA secondary structure unwinding
CF61_RS11300	COG0346	lactoylglutathione lyase activity
CF61_RS11305	COG1902	pentaerythritol trinitrate reductase activity
CF61_RS11310	COG1309	transcriptional regulator
CF61_RS11315	COG3313	Fe-S protein
CF61_RS11320	COG4989	oxidoreductase activity
CF61_RS11325	COG2032	superoxide dismutase activity
CF61_RS11330	COG1289	transmembrane transporter activity
CF61_RS11335	COG1566	PFAM secretion protein HlyD family protein
CF61_RS11350	COG3133	Outer membrane lipoprotein
CF61_RS11360	COG3895	Periplasmic Protein
CF61_RS11375	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CF61_RS11380	COG0625	glutathione transferase activity
CF61_RS11385	COG3104	oligopeptide transport
CF61_RS11395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CF61_RS11405	COG4659	FMN binding
CF61_RS11445	COG0673	inositol 2-dehydrogenase activity
CF61_RS11455	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CF61_RS11460	COG1263	PTS System
CF61_RS11460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS11465	COG1609	Transcriptional regulator
CF61_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS11475	COG1309	transcriptional regulator
CF61_RS11480	COG3250	beta-galactosidase activity
CF61_RS11505	COG5339	Protein conserved in bacteria
CF61_RS11510	COG1482	cell wall glycoprotein biosynthetic process
CF61_RS11515	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CF61_RS11515	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CF61_RS11520	COG0114	fumarate hydratase activity
CF61_RS11530	COG2205	protein histidine kinase activity
CF61_RS11535	COG0745	RESPONSE REGULATOR receiver
CF61_RS11540	COG3136	membrane protein required for alginate biosynthesis
CF61_RS11550	COG0531	amino acid
CF61_RS11560	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CF61_RS11565	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CF61_RS11570	COG0628	permease
CF61_RS11585	COG3591	Belongs to the peptidase S1B family
CF61_RS11600	COG2814	Major facilitator Superfamily
CF61_RS11605	COG0583	DNA-binding transcription factor activity
CF61_RS11610	COG1940	carbohydrate kinase activity
CF61_RS11615	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CF61_RS11625	COG3381	protein complex oligomerization
CF61_RS11630	COG3302	dmso reductase anchor subunit
CF61_RS11635	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS11640	COG0243	molybdopterin cofactor binding
CF61_RS11645	COG0243	molybdopterin cofactor binding
CF61_RS11660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF61_RS11675	COG4948	Mandelate Racemase Muconate Lactonizing
CF61_RS11680	COG1063	alcohol dehydrogenase
CF61_RS11685	COG0582	viral genome integration into host DNA
CF61_RS11695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CF61_RS11710	COG1403	HNH endonuclease
CF61_RS11715	COG0484	heat shock protein binding
CF61_RS11720	COG1278	Cold shock
CF61_RS11725	COG1278	Cold shock
CF61_RS11740	COG3772	lysozyme
CF61_RS11750	COG1278	Cold shock
CF61_RS11785	COG4220	transposase activity
CF61_RS11795	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CF61_RS11800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CF61_RS11810	COG0477	Major facilitator Superfamily
CF61_RS11815	COG0246	Mannitol dehydrogenase
CF61_RS11825	COG1802	Transcriptional regulator
CF61_RS11830	COG4221	oxidoreductase activity
CF61_RS11835	COG0339	signal peptide processing
CF61_RS11840	COG1546	Belongs to the CinA family
CF61_RS11845	COG3111	PFAM Bacterial OB fold (BOF) protein
CF61_RS11850	COG3706	GGDEF domain
CF61_RS11860	COG2814	Major facilitator Superfamily
CF61_RS11865	COG0697	spore germination
CF61_RS11875	COG4977	sequence-specific DNA binding
CF61_RS11880	COG1846	Transcriptional regulator
CF61_RS11900	COG0583	DNA-binding transcription factor activity
CF61_RS11905	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS11910	COG2066	Belongs to the glutaminase family
CF61_RS11920	COG2199	diguanylate cyclase activity
CF61_RS11930	COG3781	membrane
CF61_RS11980	COG0840	transmembrane signaling receptor activity
CF61_RS12010	COG0697	spore germination
CF61_RS12025	COG3210	domain, Protein
CF61_RS12025	COG2911	Protein conserved in bacteria
CF61_RS12030	COG1396	sequence-specific DNA binding
CF61_RS12035	COG3550	peptidyl-serine autophosphorylation
CF61_RS12040	COG4977	sequence-specific DNA binding
CF61_RS12045	COG3188	usher protein
CF61_RS12050	COG3539	Fimbrial protein
CF61_RS12055	COG3539	Fimbrial protein
CF61_RS12060	COG3539	Fimbrial protein
CF61_RS12065	COG0243	molybdopterin cofactor binding
CF61_RS12085	COG0641	radical SAM
CF61_RS12090	COG4178	(ABC) transporter
CF61_RS12095	COG4771	TonB-dependent receptor
CF61_RS12100	COG0612	Peptidase, M16
CF61_RS12110	COG0076	glutamate decarboxylase activity
CF61_RS12115	COG0531	amino acid
CF61_RS12120	COG1649	PFAM Uncharacterised BCR, COG1649
CF61_RS12125	COG3706	GGDEF domain
CF61_RS12130	COG2202	Pas domain
CF61_RS12130	COG2200	EAL domain
CF61_RS12130	COG2199	diguanylate cyclase activity
CF61_RS12135	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CF61_RS12140	COG0747	negative chemotaxis
CF61_RS12145	COG0601	transmembrane transport
CF61_RS12150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF61_RS12155	COG0444	Belongs to the ABC transporter superfamily
CF61_RS12160	COG4608	Belongs to the ABC transporter superfamily
CF61_RS12165	COG1764	response to oxidative stress
CF61_RS12185	COG1064	alcohol dehydrogenase
CF61_RS12190	COG3093	addiction module antidote protein HigA
CF61_RS12195	COG2864	formate dehydrogenase
CF61_RS12200	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS12205	COG0243	molybdopterin cofactor binding
CF61_RS12205	COG3383	formate dehydrogenase (NAD+) activity
CF61_RS12210	COG3383	formate dehydrogenase (NAD+) activity
CF61_RS12210	COG0243	molybdopterin cofactor binding
CF61_RS12215	COG0697	spore germination
CF61_RS12220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF61_RS12230	COG2223	nitrite transmembrane transporter activity
CF61_RS12235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CF61_RS12240	COG1140	nitrate reductase beta subunit
CF61_RS12245	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CF61_RS12250	COG2181	nitrate reductase activity
CF61_RS12255	COG0384	phenazine biosynthesis protein PhzF
CF61_RS12260	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CF61_RS12265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CF61_RS12280	COG5433	transposase activity
CF61_RS12310	COG0625	glutathione transferase activity
CF61_RS12315	COG1113	amino acid transport
CF61_RS12320	COG3391	amine dehydrogenase activity
CF61_RS12325	COG4772	TonB-dependent receptor
CF61_RS12330	COG1802	Transcriptional regulator
CF61_RS12335	COG2130	NADP-dependent
CF61_RS12340	COG1247	-acetyltransferase
CF61_RS12345	COG3238	Protein conserved in bacteria
CF61_RS12370	COG1177	transmembrane transport
CF61_RS12375	COG1176	ABC-type spermidine putrescine transport system, permease component I
CF61_RS12380	COG3842	ATPase activity
CF61_RS12385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CF61_RS12390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CF61_RS12395	COG1598	PFAM Uncharacterised protein family UPF0150
CF61_RS12415	COG1396	sequence-specific DNA binding
CF61_RS12420	COG3135	benzoate transporter
CF61_RS12425	COG0675	Transposase, IS605 OrfB family
CF61_RS12445	COG0500	methyltransferase
CF61_RS12450	COG1275	C4-dicarboxylate transporter malic acid transport protein
CF61_RS12455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CF61_RS12460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF61_RS12465	COG2841	Protein conserved in bacteria
CF61_RS12480	COG5383	Protein conserved in bacteria
CF61_RS12485	COG0583	DNA-binding transcription factor activity
CF61_RS12490	COG0840	transmembrane signaling receptor activity
CF61_RS12495	COG2963	transposase activity
CF61_RS12500	COG2801	Transposase and inactivated derivatives
CF61_RS12515	COG3038	cytochrome b561
CF61_RS12520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CF61_RS12525	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS12530	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CF61_RS12535	COG1643	Atp-dependent helicase
CF61_RS12545	COG0671	phosphoesterase, PA-phosphatase related
CF61_RS12545	COG2453	phosphatase
CF61_RS12550	COG2267	carboxylic ester hydrolase activity
CF61_RS12555	COG4589	Belongs to the CDS family
CF61_RS12560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CF61_RS12580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CF61_RS12585	COG3327	negative regulation of DNA-templated transcription, initiation
CF61_RS12590	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CF61_RS12595	COG0183	Belongs to the thiolase family
CF61_RS12600	COG2050	protein possibly involved in aromatic compounds catabolism
CF61_RS12605	COG1250	3-hydroxyacyl-CoA dehydrogenase
CF61_RS12610	COG1024	Enoyl-CoA hydratase
CF61_RS12615	COG1024	Enoyl-CoA hydratase
CF61_RS12620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF61_RS12625	COG2151	metal-sulfur cluster biosynthetic enzyme
CF61_RS12630	COG3396	Phenylacetate-CoA oxygenase
CF61_RS12635	COG3460	Phenylacetate-CoA oxygenase
CF61_RS12640	COG3396	Phenylacetate-CoA oxygenase
CF61_RS12645	COG2030	dehydratase
CF61_RS12645	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS12650	COG3733	amine oxidase
CF61_RS12655	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS12660	COG2207	Transcriptional regulator
CF61_RS12665	COG3784	Protein of unknown function (DUF1318)
CF61_RS12675	COG2911	Protein conserved in bacteria
CF61_RS12680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CF61_RS12685	COG3187	Heat shock protein
CF61_RS12690	COG3042	response to heat
CF61_RS12695	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CF61_RS12695	COG1013	pyruvate-flavodoxin oxidoreductase activity
CF61_RS12695	COG0674	pyruvate-flavodoxin oxidoreductase activity
CF61_RS12695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CF61_RS12700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF61_RS12705	COG0589	response to stress
CF61_RS12715	COG0513	Belongs to the DEAD box helicase family
CF61_RS12730	COG3706	GGDEF domain
CF61_RS12735	COG2840	Smr protein MutS2
CF61_RS12745	COG0583	DNA-binding transcription factor activity
CF61_RS12750	COG1473	amidohydrolase
CF61_RS12755	COG1473	amidohydrolase
CF61_RS12765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CF61_RS12770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CF61_RS12775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF61_RS12780	COG0589	response to stress
CF61_RS12785	COG3182	Iron-regulated membrane protein
CF61_RS12790	COG0668	transmembrane transport
CF61_RS12795	COG4166	transmembrane transport
CF61_RS12805	COG0583	DNA-binding transcription factor activity
CF61_RS12810	COG1073	alpha beta
CF61_RS12815	COG0702	epimerase
CF61_RS12820	COG2866	Carboxypeptidase
CF61_RS12825	COG4948	Mandelate Racemase Muconate Lactonizing
CF61_RS12830	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CF61_RS12835	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CF61_RS12845	COG3106	COG3106 Predicted ATPase
CF61_RS12850	COG1609	Transcriptional regulator
CF61_RS12860	COG3842	ATPase activity
CF61_RS12865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF61_RS12870	COG1554	hydrolase, family 65, central catalytic
CF61_RS12875	COG0673	inositol 2-dehydrogenase activity
CF61_RS12885	COG1063	alcohol dehydrogenase
CF61_RS12890	COG0395	ABC-type sugar transport system, permease component
CF61_RS12895	COG1175	transmembrane transport
CF61_RS12900	COG1653	transport
CF61_RS12905	COG0366	Alpha amylase catalytic
CF61_RS12910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CF61_RS12920	COG1983	PspC domain protein
CF61_RS12930	COG1842	Phage shock protein A
CF61_RS12935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CF61_RS12940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CF61_RS12945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CF61_RS12950	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS12955	COG1917	Cupin 2, conserved barrel domain protein
CF61_RS12955	COG1396	sequence-specific DNA binding
CF61_RS12960	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CF61_RS12965	COG0174	glutamine synthetase
CF61_RS12970	COG0531	amino acid
CF61_RS12985	COG4166	transmembrane transport
CF61_RS12990	COG4168	peptide transport system, permease
CF61_RS12995	COG4171	peptide transport system, permease
CF61_RS13000	COG4172	Belongs to the ABC transporter superfamily
CF61_RS13005	COG4172	Belongs to the ABC transporter superfamily
CF61_RS13010	COG2852	Protein conserved in bacteria
CF61_RS13020	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CF61_RS13025	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CF61_RS13025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CF61_RS13040	COG5001	Diguanylate cyclase
CF61_RS13050	COG1349	DNA-binding transcription factor activity
CF61_RS13060	COG0023	Translation Initiation Factor
CF61_RS13070	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CF61_RS13075	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CF61_RS13080	COG0671	phosphoesterase, PA-phosphatase related
CF61_RS13090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CF61_RS13110	COG0598	Magnesium transport protein CorA
CF61_RS13120	COG3698	Phosphodiester glycosidase
CF61_RS13125	COG1662	PFAM IS1 transposase
CF61_RS13125	COG3677	Transposase
CF61_RS13130	COG1662	PFAM IS1 transposase
CF61_RS13145	COG0583	DNA-binding transcription factor activity
CF61_RS13150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CF61_RS13165	COG0616	signal peptide processing
CF61_RS13175	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS13180	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CF61_RS13185	COG1187	pseudouridine synthase activity
CF61_RS13195	COG0009	L-threonylcarbamoyladenylate synthase
CF61_RS13200	COG0613	PHP domain protein
CF61_RS13205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CF61_RS13210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CF61_RS13210	COG0512	Glutamine amidotransferase of anthranilate synthase
CF61_RS13215	COG0134	indole-3-glycerol-phosphate synthase activity
CF61_RS13215	COG0135	phosphoribosylanthranilate isomerase activity
CF61_RS13230	COG3729	General stress protein
CF61_RS13235	COG3685	Protein conserved in bacteria
CF61_RS13240	COG3685	Protein conserved in bacteria
CF61_RS13245	COG3047	cAMP biosynthetic process
CF61_RS13260	COG1607	acyl-coa hydrolase
CF61_RS13265	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CF61_RS13270	COG2350	Protein conserved in bacteria
CF61_RS13275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CF61_RS13295	COG4608	Belongs to the ABC transporter superfamily
CF61_RS13300	COG0444	Belongs to the ABC transporter superfamily
CF61_RS13305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CF61_RS13310	COG0601	transmembrane transport
CF61_RS13315	COG4166	transmembrane transport
CF61_RS13320	COG2095	MarC family integral membrane protein
CF61_RS13325	COG1454	alcohol dehydrogenase
CF61_RS13325	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS13330	COG1435	thymidine kinase activity
CF61_RS13340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CF61_RS13345	COG0745	RESPONSE REGULATOR receiver
CF61_RS13350	COG1752	Esterase of the alpha-beta hydrolase superfamily
CF61_RS13360	COG0788	formyltetrahydrofolate deformylase activity
CF61_RS13380	COG2181	nitrate reductase activity
CF61_RS13385	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CF61_RS13390	COG1140	nitrate reductase beta subunit
CF61_RS13395	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CF61_RS13400	COG2223	nitrite transmembrane transporter activity
CF61_RS13410	COG3850	Histidine kinase
CF61_RS13415	COG2197	response regulator
CF61_RS13420	COG4932	domain protein
CF61_RS13425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CF61_RS13430	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CF61_RS13435	COG4572	Cation transport regulator
CF61_RS13440	COG0387	Pfam Sodium calcium exchanger
CF61_RS13455	COG2963	transposase activity
CF61_RS13460	COG2801	Transposase and inactivated derivatives
CF61_RS13475	COG2912	Transglutaminase-like superfamily
CF61_RS13480	COG3094	Invasion gene expression up-regulator, SirB
CF61_RS13485	COG2890	protein-(glutamine-N5) methyltransferase activity
CF61_RS13510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CF61_RS13515	COG0659	secondary active sulfate transmembrane transporter activity
CF61_RS13530	COG0012	GTP binding
CF61_RS13540	COG3468	outer membrane autotransporter barrel domain protein
CF61_RS13545	COG3284	Transcriptional regulator
CF61_RS13550	COG2376	Dihydroxyacetone kinase
CF61_RS13555	COG1461	Dihydroxyacetone kinase
CF61_RS13560	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CF61_RS13560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS13560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF61_RS13580	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CF61_RS13590	COG1619	proteins homologs of microcin C7 resistance protein MccF
CF61_RS13600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CF61_RS13610	COG2719	SpoVR family
CF61_RS13625	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CF61_RS13630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CF61_RS13635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CF61_RS13650	COG0179	Fumarylacetoacetate (FAA) hydrolase
CF61_RS13680	COG2894	cell division
CF61_RS13735	COG2200	EAL domain
CF61_RS13760	COG2200	EAL domain
CF61_RS13765	COG0789	Transcriptional regulator
CF61_RS13770	COG5562	phage envelope protein
CF61_RS13785	COG0538	isocitrate dehydrogenase activity
CF61_RS13790	COG1187	pseudouridine synthase activity
CF61_RS13810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CF61_RS13815	COG0745	RESPONSE REGULATOR receiver
CF61_RS13820	COG2205	protein histidine kinase activity
CF61_RS13825	COG2850	peptidyl-arginine hydroxylation
CF61_RS13850	COG1177	transmembrane transport
CF61_RS13855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CF61_RS13865	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CF61_RS13870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CF61_RS13880	COG4591	ABC-type transport system involved in lipoprotein release permease component
CF61_RS13885	COG1136	(ABC) transporter
CF61_RS13890	COG4591	ABC-type transport system involved in lipoprotein release permease component
CF61_RS13900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CF61_RS13905	COG1388	LysM domain
CF61_RS13905	COG1376	ErfK ybiS ycfS ynhG family protein
CF61_RS13915	COG1309	transcriptional regulator
CF61_RS13920	COG3134	Outer membrane lipoprotein
CF61_RS13925	COG1252	NADH dehydrogenase
CF61_RS13945	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CF61_RS13950	COG5633	Lipoprotein
CF61_RS13955	COG0537	adenosine 5'-monophosphoramidase activity
CF61_RS13960	COG4773	Receptor
CF61_RS13965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS13965	COG1263	PTS System
CF61_RS13970	COG0084	hydrolase, TatD family'
CF61_RS13975	COG0470	DNA polymerase III
CF61_RS13985	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CF61_RS13990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CF61_RS13995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CF61_RS14005	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS14010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CF61_RS14030	COG1399	metal-binding, possibly nucleic acid-binding protein
CF61_RS14035	COG0424	maF-like protein
CF61_RS14040	COG0564	pseudouridine synthase activity
CF61_RS14050	COG1530	ribonuclease E activity
CF61_RS14055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CF61_RS14060	COG1256	bacterial-type flagellum assembly
CF61_RS14065	COG1705	Flagellar rod assembly protein muramidase FlgJ
CF61_RS14065	COG3951	Flagellar rod assembly protein muramidase FlgJ
CF61_RS14080	COG4786	Flagellar basal body rod
CF61_RS14085	COG4787	bacterial-type flagellum-dependent cell motility
CF61_RS14090	COG1749	Flagellar hook protein flgE
CF61_RS14095	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CF61_RS14100	COG1558	bacterial-type flagellum-dependent cell motility
CF61_RS14105	COG1815	bacterial-type flagellum-dependent cell motility
CF61_RS14110	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CF61_RS14115	COG2747	anti-sigma28 factor FlgM
CF61_RS14120	COG3418	PFAM FlgN family protein
CF61_RS14125	COG0728	peptidoglycan biosynthetic process
CF61_RS14130	COG0673	inositol 2-dehydrogenase activity
CF61_RS14140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CF61_RS14150	COG2999	glutathione oxidoreductase activity
CF61_RS14185	COG3038	cytochrome b561
CF61_RS14190	COG2353	YceI-like domain
CF61_RS14200	COG1560	Kdo2-lipid A biosynthetic process
CF61_RS14220	COG5645	(Lipo)protein
CF61_RS14225	COG2943	transferase activity, transferring hexosyl groups
CF61_RS14250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CF61_RS14255	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CF61_RS14260	COG1662	PFAM IS1 transposase
CF61_RS14290	COG2197	response regulator
CF61_RS14305	COG1462	curli production assembly transport component CsgG
CF61_RS14315	COG3381	protein complex oligomerization
CF61_RS14360	COG3706	GGDEF domain
CF61_RS14365	COG0457	Tetratricopeptide repeat
CF61_RS14370	COG0726	polysaccharide deacetylase
CF61_RS14370	COG1649	PFAM Uncharacterised BCR, COG1649
CF61_RS14375	COG1215	transferase activity, transferring glycosyl groups
CF61_RS14380	COG3658	cytochrome
CF61_RS14385	COG1702	phosphate starvation-inducible protein PhoH
CF61_RS14395	COG2837	iron assimilation
CF61_RS14400	COG2822	iron ion transport
CF61_RS14415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CF61_RS14425	COG0506	proline dehydrogenase activity
CF61_RS14425	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CF61_RS14425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CF61_RS14430	COG1309	transcriptional regulator
CF61_RS14440	COG1335	isochorismatase
CF61_RS14465	COG2233	PERMEase
CF61_RS14470	COG3729	General stress protein
CF61_RS14515	COG0243	molybdopterin cofactor binding
CF61_RS14520	COG3005	denitrification pathway
CF61_RS14525	COG0745	RESPONSE REGULATOR receiver
CF61_RS14530	COG1879	ABC-type sugar transport system periplasmic component
CF61_RS14535	COG2198	Histidine kinase
CF61_RS14535	COG2205	protein histidine kinase activity
CF61_RS14535	COG0784	Response regulator, receiver
CF61_RS14540	COG0348	domain, Protein
CF61_RS14555	COG1278	Cold shock
CF61_RS14560	COG1278	Cold shock
CF61_RS14585	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF61_RS14590	COG1596	polysaccharide export
CF61_RS14595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CF61_RS14600	COG3206	protein involved in exopolysaccharide biosynthesis
CF61_RS14600	COG0489	protein tyrosine kinase activity
CF61_RS14615	COG1294	oxidase, subunit
CF61_RS14620	COG1271	oxidase subunit
CF61_RS14625	COG1773	rubredoxin
CF61_RS14630	COG1999	signal sequence binding
CF61_RS14635	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CF61_RS14640	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CF61_RS14645	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CF61_RS14650	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CF61_RS14660	COG0670	Belongs to the BI1 family
CF61_RS14665	COG2920	part of a sulfur-relay system
CF61_RS14670	COG1254	Belongs to the acylphosphatase family
CF61_RS14685	COG1832	CoA-binding protein
CF61_RS14705	COG0210	DNA helicase
CF61_RS14710	COG3304	Inner membrane component domain
CF61_RS14715	COG1289	transmembrane transporter activity
CF61_RS14720	COG3070	regulator of competence-specific genes
CF61_RS14735	COG2885	chlorophyll binding
CF61_RS14735	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CF61_RS14745	COG1067	ATP-dependent peptidase activity
CF61_RS14755	COG3130	regulation of translation
CF61_RS14760	COG3009	Protein conserved in bacteria
CF61_RS14765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CF61_RS14765	COG3008	intermembrane lipid transfer
CF61_RS14770	COG2995	paraquat-inducible protein a
CF61_RS14775	COG0488	(ABC) transporter
CF61_RS14785	COG3217	Mosc domain protein beta barrel domain protein
CF61_RS14785	COG0633	Ferredoxin
CF61_RS14800	COG3121	Chaperone
CF61_RS14805	COG3539	Fimbrial protein
CF61_RS14810	COG3539	Fimbrial protein
CF61_RS14815	COG3539	Fimbrial protein
CF61_RS14820	COG3188	usher protein
CF61_RS14825	COG3121	Chaperone
CF61_RS14830	COG3539	Fimbrial protein
CF61_RS14835	COG0431	NADPH-dependent FMN reductase
CF61_RS14840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CF61_RS14850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CF61_RS14855	COG1116	anion transmembrane transporter activity
CF61_RS14860	COG0308	aminopeptidase N
CF61_RS14885	COG1448	Aminotransferase
CF61_RS14890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CF61_RS14895	COG3108	Peptidase M15
CF61_RS14900	COG2989	Protein conserved in bacteria
CF61_RS14910	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CF61_RS14920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CF61_RS14925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CF61_RS14930	COG3173	Aminoglycoside phosphotransferase
CF61_RS14945	COG3214	Protein conserved in bacteria
CF61_RS14955	COG1132	(ABC) transporter
CF61_RS14960	COG2333	competence protein COMEC
CF61_RS14960	COG0658	competence protein
CF61_RS14970	COG0539	negative regulation of cytoplasmic translation
CF61_RS14980	COG0501	Belongs to the peptidase M48B family
CF61_RS14995	COG2323	membrane
CF61_RS15000	COG1944	ATP diphosphatase activity
CF61_RS15005	COG2116	formate transmembrane transporter activity
CF61_RS15010	COG1882	Formate acetyltransferase
CF61_RS15015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CF61_RS15020	COG2249	NAD(P)H dehydrogenase (quinone) activity
CF61_RS15025	COG0583	DNA-binding transcription factor activity
CF61_RS15030	COG0531	amino acid
CF61_RS15040	COG1335	isochorismatase
CF61_RS15045	COG3302	dmso reductase anchor subunit
CF61_RS15050	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS15055	COG0243	molybdopterin cofactor binding
CF61_RS15065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CF61_RS15075	COG1178	ABC-type Fe3 transport system permease component
CF61_RS15075	COG1674	ftsk spoiiie
CF61_RS15080	COG1522	sequence-specific DNA binding
CF61_RS15085	COG0492	ferredoxin-NADP+ reductase activity
CF61_RS15090	COG4988	ABC transporter
CF61_RS15095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CF61_RS15115	COG0542	response to heat
CF61_RS15125	COG1278	Cold shock
CF61_RS15130	COG1136	(ABC) transporter
CF61_RS15130	COG0577	efflux transmembrane transporter activity
CF61_RS15135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF61_RS15140	COG2990	Protein conserved in bacteria
CF61_RS15145	COG3593	DNA synthesis involved in DNA repair
CF61_RS15160	COG2431	L-lysine efflux transmembrane transporter activity
CF61_RS15170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF61_RS15175	COG0028	Belongs to the TPP enzyme family
CF61_RS15180	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CF61_RS15185	COG0702	epimerase
CF61_RS15190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CF61_RS15195	COG3023	N-Acetylmuramoyl-L-alanine amidase
CF61_RS15210	COG1126	abc transporter atp-binding protein
CF61_RS15215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF61_RS15220	COG4215	(ABC) transporter
CF61_RS15225	COG4160	amino acid transport
CF61_RS15230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF61_RS15245	COG1177	transmembrane transport
CF61_RS15250	COG1176	ABC-type spermidine putrescine transport system, permease component I
CF61_RS15255	COG3842	ATPase activity
CF61_RS15260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CF61_RS15280	COG0778	Nitroreductase
CF61_RS15285	COG0778	Nitroreductase
CF61_RS15295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CF61_RS15310	COG3226	Transcriptional regulator
CF61_RS15315	COG0738	Major facilitator superfamily
CF61_RS15320	COG0561	phosphatase activity
CF61_RS15330	COG2814	Major facilitator Superfamily
CF61_RS15335	COG0671	phosphoesterase, PA-phosphatase related
CF61_RS15340	COG1349	DNA-binding transcription factor activity
CF61_RS15345	COG1686	Belongs to the peptidase S11 family
CF61_RS15350	COG0625	glutathione transferase activity
CF61_RS15370	COG2199	diguanylate cyclase activity
CF61_RS15375	COG2200	EAL domain
CF61_RS15390	COG0747	negative chemotaxis
CF61_RS15400	COG1446	asparaginase
CF61_RS15405	COG0303	'Molybdopterin
CF61_RS15410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CF61_RS15415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CF61_RS15420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CF61_RS15425	COG1882	Formate acetyltransferase
CF61_RS15430	COG0561	phosphatase activity
CF61_RS15440	COG0488	(ABC) transporter
CF61_RS15445	COG1376	ErfK ybiS ycfS ynhG family protein
CF61_RS15450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CF61_RS15455	COG1321	iron dependent repressor
CF61_RS15465	COG2194	sulfuric ester hydrolase activity
CF61_RS15470	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CF61_RS15475	COG5006	permease, DMT superfamily
CF61_RS15490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF61_RS15495	COG0765	amino acid transport
CF61_RS15500	COG1126	abc transporter atp-binding protein
CF61_RS15505	COG0668	transmembrane transport
CF61_RS15520	COG4774	siderophore transport
CF61_RS15530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CF61_RS15540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CF61_RS15545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CF61_RS15550	COG1199	ATP-dependent helicase activity
CF61_RS15555	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CF61_RS15560	COG0513	Belongs to the DEAD box helicase family
CF61_RS15565	COG1309	transcriptional regulator
CF61_RS15575	COG1131	(ABC) transporter
CF61_RS15580	COG0842	Transport permease protein
CF61_RS15585	COG0842	Transport permease protein
CF61_RS15595	COG3568	Endonuclease Exonuclease Phosphatase
CF61_RS15600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CF61_RS15605	COG0392	lysyltransferase activity
CF61_RS15610	COG0670	Belongs to the BI1 family
CF61_RS15615	COG0670	Belongs to the BI1 family
CF61_RS15620	COG0314	molybdopterin synthase activity
CF61_RS15625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CF61_RS15635	COG0521	Mo-molybdopterin cofactor biosynthetic process
CF61_RS15650	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CF61_RS15660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CF61_RS15665	COG2226	methyltransferase
CF61_RS15680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CF61_RS15685	COG1881	PFAM PEBP family protein
CF61_RS15800	COG0494	nUDIX hydrolase
CF61_RS15890	COG0305	Participates in initiation and elongation during chromosome replication
CF61_RS15950	COG4712	double-strand break repair protein
CF61_RS16005	COG0582	viral genome integration into host DNA
CF61_RS16010	COG4677	pectinesterase activity
CF61_RS16015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CF61_RS16020	COG0471	metal ion transport
CF61_RS16025	COG2828	Protein conserved in bacteria
CF61_RS16030	COG0583	DNA-binding transcription factor activity
CF61_RS16040	COG0561	phosphatase activity
CF61_RS16045	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CF61_RS16050	COG4149	molybdate abc transporter
CF61_RS16055	COG0725	ABC transporter, periplasmic molybdate-binding protein
CF61_RS16065	COG3585	molybdate ion transport
CF61_RS16065	COG2005	Transcriptional regulator
CF61_RS16075	COG1119	ATPase activity
CF61_RS16080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CF61_RS16085	COG1085	galactose-1-phosphate uridylyltransferase
CF61_RS16095	COG2017	converts alpha-aldose to the beta-anomer
CF61_RS16105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CF61_RS16120	COG1230	cation diffusion facilitator family transporter
CF61_RS16125	COG3201	nicotinamide mononucleotide transporter
CF61_RS16170	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CF61_RS16175	COG2885	chlorophyll binding
CF61_RS16185	COG3064	Membrane
CF61_RS16190	COG0848	biopolymer transport protein
CF61_RS16195	COG0811	peptide transport
CF61_RS16200	COG0824	Thioesterase
CF61_RS16205	COG3790	cyd operon protein YbgE
CF61_RS16210	COG4890	Cyd operon protein YbgT
CF61_RS16215	COG1294	oxidase, subunit
CF61_RS16220	COG1271	oxidase subunit
CF61_RS16230	COG0383	alpha-mannosidase activity
CF61_RS16235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS16235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS16235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS16240	COG2188	Transcriptional regulator
CF61_RS16245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CF61_RS16255	COG0508	dehydrogenase complex catalyzes the overall conversion of
CF61_RS16260	COG0567	Dehydrogenase, E1 component
CF61_RS16270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CF61_RS16275	COG1053	succinate dehydrogenase
CF61_RS16280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CF61_RS16285	COG2009	succinate dehydrogenase
CF61_RS16295	COG0372	Belongs to the citrate synthase family
CF61_RS16300	COG3539	Fimbrial protein
CF61_RS16305	COG3188	usher protein
CF61_RS16310	COG3121	Chaperone
CF61_RS16315	COG3539	Fimbrial protein
CF61_RS16320	COG3180	Ammonia monooxygenase
CF61_RS16335	COG1984	allophanate hydrolase subunit 2
CF61_RS16340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CF61_RS16345	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CF61_RS16350	COG3104	oligopeptide transport
CF61_RS16355	COG0415	Belongs to the DNA photolyase family
CF61_RS16360	COG3272	Protein of unknown function (DUF1722)
CF61_RS16365	COG5433	transposase activity
CF61_RS16375	COG5433	transposase activity
CF61_RS16385	COG3209	COG3209 Rhs family protein
CF61_RS16415	COG2205	protein histidine kinase activity
CF61_RS16420	COG0745	RESPONSE REGULATOR receiver
CF61_RS16430	COG1982	Orn Lys Arg decarboxylase major
CF61_RS16435	COG0531	amino acid
CF61_RS16455	COG0033	Phosphoglucomutase
CF61_RS16460	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CF61_RS16465	COG0596	Alpha beta hydrolase
CF61_RS16475	COG0716	FMN binding
CF61_RS16490	COG0735	belongs to the Fur family
CF61_RS16510	COG2190	(PTS) system
CF61_RS16510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS16510	COG1263	PTS System
CF61_RS16520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CF61_RS16525	COG1846	Transcriptional regulator
CF61_RS16525	COG1940	carbohydrate kinase activity
CF61_RS16530	COG0647	UMP catabolic process
CF61_RS16535	COG0367	asparagine synthase
CF61_RS16575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CF61_RS16585	COG1702	phosphate starvation-inducible protein PhoH
CF61_RS16595	COG4535	Mg2 and Co2 transporter CorC
CF61_RS16600	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CF61_RS16610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CF61_RS16615	COG0765	amino acid transport
CF61_RS16620	COG0765	amino acid transport
CF61_RS16625	COG1126	abc transporter atp-binding protein
CF61_RS16635	COG0443	Heat shock 70 kDa protein
CF61_RS16640	COG2214	Heat shock protein DnaJ domain protein
CF61_RS16650	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CF61_RS16655	COG2214	Heat shock protein DnaJ domain protein
CF61_RS16665	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CF61_RS16670	COG2888	peptidyl-tyrosine sulfation
CF61_RS16685	COG1466	dna polymerase III delta subunit
CF61_RS16695	COG0406	alpha-ribazole phosphatase activity
CF61_RS16700	COG0799	negative regulation of ribosome biogenesis
CF61_RS16710	COG0768	penicillin binding
CF61_RS16715	COG0772	Belongs to the SEDS family
CF61_RS16720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CF61_RS16725	COG1686	Belongs to the peptidase S11 family
CF61_RS16745	COG0583	DNA-binding transcription factor activity
CF61_RS16755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CF61_RS16760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CF61_RS16780	COG3069	C4-dicarboxylate transmembrane transporter activity
CF61_RS16785	COG4565	transcriptional regulatory protein
CF61_RS16790	COG3290	protein histidine kinase activity
CF61_RS16795	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CF61_RS16805	COG2301	Belongs to the HpcH HpaI aldolase family
CF61_RS16810	COG3051	citrate lyase alpha subunit
CF61_RS16825	COG0471	metal ion transport
CF61_RS16830	COG3719	Belongs to the RNase T2 family
CF61_RS16835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CF61_RS16845	COG1063	alcohol dehydrogenase
CF61_RS16850	COG0589	response to stress
CF61_RS16855	COG3634	alkyl hydroperoxide reductase activity
CF61_RS16860	COG0450	alkyl hydroperoxide reductase
CF61_RS16865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CF61_RS16870	COG0583	DNA-binding transcription factor activity
CF61_RS16875	COG3969	phosphoadenosine phosphosulfate
CF61_RS16880	COG1475	DNA binding
CF61_RS16885	COG0436	Aminotransferase
CF61_RS16890	COG0371	Dehydrogenase
CF61_RS16895	COG2879	small protein
CF61_RS16900	COG1966	Carbon starvation protein
CF61_RS16905	COG2050	protein possibly involved in aromatic compounds catabolism
CF61_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS16915	COG1535	isochorismatase
CF61_RS16915	COG3433	isochorismatase activity
CF61_RS16920	COG1021	2,3-dihydroxybenzoate-AMP ligase
CF61_RS16925	COG1169	isochorismate synthase
CF61_RS16930	COG4592	Periplasmic binding protein
CF61_RS16940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF61_RS16945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF61_RS16950	COG1120	ATPase activity
CF61_RS16955	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CF61_RS16960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CF61_RS16960	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CF61_RS16965	COG3251	PFAM MbtH domain protein
CF61_RS16970	COG2382	esterase
CF61_RS16975	COG4771	TonB-dependent receptor
CF61_RS16980	COG2977	Belongs to the P-Pant transferase superfamily
CF61_RS16985	COG3385	transposase activity
CF61_RS17010	COG2315	Protein conserved in bacteria
CF61_RS17015	COG0778	Nitroreductase
CF61_RS17020	COG0668	transmembrane transport
CF61_RS17025	COG1113	amino acid transport
CF61_RS17030	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF61_RS17035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF61_RS17040	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF61_RS17045	COG1538	Outer membrane efflux protein
CF61_RS17050	COG0745	RESPONSE REGULATOR receiver
CF61_RS17055	COG5002	protein histidine kinase activity
CF61_RS17070	COG4104	PAAR repeat-containing protein
CF61_RS17070	COG3209	COG3209 Rhs family protein
CF61_RS17090	COG5433	transposase activity
CF61_RS17100	COG4783	chaperone-mediated protein folding
CF61_RS17110	COG2207	Transcriptional regulator
CF61_RS17120	COG2197	response regulator
CF61_RS17125	COG3539	Fimbrial protein
CF61_RS17130	COG3539	Fimbrial protein
CF61_RS17135	COG3188	usher protein
CF61_RS17140	COG3121	Chaperone
CF61_RS17145	COG3539	Fimbrial protein
CF61_RS17155	COG2501	S4 domain
CF61_RS17160	COG1988	membrane-bound metal-dependent
CF61_RS17170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CF61_RS17180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CF61_RS17185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CF61_RS17190	COG0549	Belongs to the carbamate kinase family
CF61_RS17200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CF61_RS17205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CF61_RS17210	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CF61_RS17215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CF61_RS17220	COG3257	ureidoglycine aminohydrolase activity
CF61_RS17225	COG1929	Belongs to the glycerate kinase type-1 family
CF61_RS17230	COG2233	PERMEase
CF61_RS17240	COG1953	Uracil, thiamine, allantoin
CF61_RS17245	COG2084	Dehydrogenase
CF61_RS17250	COG3622	Belongs to the hyi family
CF61_RS17255	COG3960	tartronate-semialdehyde synthase activity
CF61_RS17260	COG1414	Transcriptional regulator
CF61_RS17270	COG0583	DNA-binding transcription factor activity
CF61_RS17280	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CF61_RS17285	COG4181	ATPase activity
CF61_RS17290	COG2755	lipolytic protein G-D-S-L family
CF61_RS17295	COG0300	oxidoreductase activity
CF61_RS17300	COG3118	belongs to the thioredoxin family
CF61_RS17305	COG0390	transport system, permease component
CF61_RS17310	COG4619	ABC transporter
CF61_RS17315	COG0330	HflC and HflK could
CF61_RS17320	COG1585	Membrane protein implicated in regulation of membrane protease activity
CF61_RS17325	COG0789	Transcriptional regulator
CF61_RS17330	COG0531	amino acid
CF61_RS17340	COG2217	Heavy metal translocating P-type atpase
CF61_RS17345	COG3093	addiction module antidote protein HigA
CF61_RS17350	COG3735	TraB family
CF61_RS17355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CF61_RS17360	COG0737	Belongs to the 5'-nucleotidase family
CF61_RS17365	COG2223	nitrite transmembrane transporter activity
CF61_RS17370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CF61_RS17370	COG4651	solute:proton antiporter activity
CF61_RS17375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF61_RS17410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CF61_RS17420	COG2832	Protein of unknown function (DUF454)
CF61_RS17425	COG3923	Primosomal replication protein n
CF61_RS17440	COG3264	Mechanosensitive ion channel
CF61_RS17440	COG1196	nuclear chromosome segregation
CF61_RS17445	COG1309	transcriptional regulator
CF61_RS17450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CF61_RS17455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CF61_RS17470	COG0110	maltose O-acetyltransferase activity
CF61_RS17480	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CF61_RS17485	COG5507	3-demethylubiquinone-9 3-methyltransferase
CF61_RS17490	COG3695	enzyme binding
CF61_RS17495	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CF61_RS17500	COG1946	Acyl-CoA thioesterase
CF61_RS17505	COG0004	ammonium transporteR
CF61_RS17510	COG0347	Belongs to the P(II) protein family
CF61_RS17515	COG1132	(ABC) transporter
CF61_RS17520	COG1132	(ABC) transporter
CF61_RS17525	COG1522	sequence-specific DNA binding
CF61_RS17535	COG4533	DNA binding
CF61_RS17545	COG0824	Thioesterase
CF61_RS17550	COG1555	photosystem II stabilization
CF61_RS17555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CF61_RS17560	COG0776	regulation of translation
CF61_RS17565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CF61_RS17590	COG0271	Belongs to the BolA IbaG family
CF61_RS17595	COG3056	Lipoprotein
CF61_RS17600	COG2223	nitrite transmembrane transporter activity
CF61_RS17605	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CF61_RS17610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CF61_RS17615	COG1845	cytochrome c oxidase, subunit III
CF61_RS17620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CF61_RS17630	COG2814	Major facilitator Superfamily
CF61_RS17640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CF61_RS17645	COG0693	protein deglycase activity
CF61_RS17660	COG0142	geranyltranstransferase activity
CF61_RS17670	COG0667	Aldo Keto reductase
CF61_RS17675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CF61_RS17680	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CF61_RS17695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CF61_RS17695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CF61_RS17705	COG4238	major outer membrane lipoprotein
CF61_RS17710	COG3248	Nucleoside-binding outer membrane protein
CF61_RS17720	COG1403	HNH endonuclease
CF61_RS17725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CF61_RS17730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CF61_RS17735	COG1862	Preprotein translocase
CF61_RS17755	COG0366	Alpha amylase catalytic
CF61_RS17760	COG1113	amino acid transport
CF61_RS17765	COG1114	Component of the transport system for branched-chain amino acids
CF61_RS17770	COG5002	protein histidine kinase activity
CF61_RS17775	COG0745	RESPONSE REGULATOR receiver
CF61_RS17780	COG0420	3'-5' exonuclease activity
CF61_RS17785	COG0419	ATPase involved in DNA repair
CF61_RS17790	COG2814	Major facilitator Superfamily
CF61_RS17795	COG1940	carbohydrate kinase activity
CF61_RS17815	COG4126	flavin adenine dinucleotide binding
CF61_RS17840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CF61_RS17845	COG3706	GGDEF domain
CF61_RS17855	COG1785	Belongs to the alkaline phosphatase family
CF61_RS17870	COG1181	Belongs to the D-alanine--D-alanine ligase family
CF61_RS17890	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CF61_RS17900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF61_RS17905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CF61_RS17910	COG3468	outer membrane autotransporter barrel domain protein
CF61_RS17915	COG0113	porphobilinogen synthase activity
CF61_RS17920	COG2175	clavaminate synthase activity
CF61_RS17925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CF61_RS17935	COG4521	taurine ABC transporter
CF61_RS17940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CF61_RS17945	COG1215	transferase activity, transferring glycosyl groups
CF61_RS17975	COG3122	Protein conserved in bacteria
CF61_RS17980	COG2814	Major facilitator Superfamily
CF61_RS17995	COG3971	2-oxopent-4-enoate hydratase activity
CF61_RS18015	COG1414	Transcriptional regulator
CF61_RS18020	COG1609	Transcriptional regulator
CF61_RS18025	COG3250	beta-galactosidase activity
CF61_RS18030	COG2223	nitrite transmembrane transporter activity
CF61_RS18035	COG0110	maltose O-acetyltransferase activity
CF61_RS18040	COG2807	transmembrane transport
CF61_RS18050	COG0288	reversible hydration of carbon dioxide
CF61_RS18055	COG0583	DNA-binding transcription factor activity
CF61_RS18060	COG0402	S-adenosylhomocysteine deaminase activity
CF61_RS18065	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CF61_RS18070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CF61_RS18075	COG2079	MmgE PrpD family protein
CF61_RS18080	COG0372	Belongs to the citrate synthase family
CF61_RS18085	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CF61_RS18090	COG3829	transcription factor binding
CF61_RS18100	COG1280	lysine exporter protein (LysE YggA)
CF61_RS18115	COG1064	alcohol dehydrogenase
CF61_RS18120	COG0402	S-adenosylhomocysteine deaminase activity
CF61_RS18125	COG0549	Belongs to the carbamate kinase family
CF61_RS18135	COG1304	FMN binding
CF61_RS18140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CF61_RS18150	COG0666	response to abiotic stimulus
CF61_RS18160	COG0583	DNA-binding transcription factor activity
CF61_RS18165	COG2771	luxR family
CF61_RS18165	COG2200	EAL domain
CF61_RS18175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CF61_RS18205	COG1556	Lactate utilization protein
CF61_RS18210	COG1139	Iron-sulfur cluster binding protein
CF61_RS18215	COG0247	lactate metabolic process
CF61_RS18220	COG2207	Transcriptional regulator
CF61_RS18225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF61_RS18235	COG3059	membrane
CF61_RS18240	COG3708	Transcriptional regulator
CF61_RS18240	COG2207	Transcriptional regulator
CF61_RS18245	COG1388	LysM domain
CF61_RS18285	COG3188	usher protein
CF61_RS18295	COG3121	Chaperone
CF61_RS18300	COG0727	PFAM Uncharacterised protein family (UPF0153)
CF61_RS18305	COG3477	response to acidic pH
CF61_RS18310	COG2080	2 iron, 2 sulfur cluster binding
CF61_RS18315	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CF61_RS18320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CF61_RS18325	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CF61_RS18330	COG0583	DNA-binding transcription factor activity
CF61_RS18370	COG1802	Transcriptional regulator
CF61_RS18370	COG4626	Terminase
CF61_RS18425	COG1403	HNH endonuclease
CF61_RS18450	COG1846	Transcriptional regulator
CF61_RS18490	COG5532	Uncharacterized conserved protein (DUF2303)
CF61_RS18495	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CF61_RS18510	COG0582	viral genome integration into host DNA
CF61_RS18530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CF61_RS18550	COG2195	Cleaves the N-terminal amino acid of tripeptides
CF61_RS18555	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CF61_RS18560	COG1690	Belongs to the RtcB family
CF61_RS18565	COG0454	-acetyltransferase
CF61_RS18575	COG2161	toxin-antitoxin pair type II binding
CF61_RS18590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CF61_RS18595	COG1191	sigma factor activity
CF61_RS18620	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CF61_RS18625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CF61_RS18640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CF61_RS18665	COG4786	Flagellar basal body rod
CF61_RS18670	COG4787	bacterial-type flagellum-dependent cell motility
CF61_RS18675	COG1749	Flagellar hook protein flgE
CF61_RS18685	COG1558	bacterial-type flagellum-dependent cell motility
CF61_RS18690	COG1815	bacterial-type flagellum-dependent cell motility
CF61_RS18720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CF61_RS18740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CF61_RS18750	COG1677	Flagellar hook-basal body complex protein FliE
CF61_RS18775	COG1987	bacterial-type flagellum assembly
CF61_RS18795	COG1943	Transposase
CF61_RS18800	COG0791	NLP P60 protein
CF61_RS18805	COG3034	peptidoglycan biosynthetic process
CF61_RS18810	COG0121	glutamine amidotransferase
CF61_RS18820	COG1960	acyl-CoA dehydrogenase activity
CF61_RS18830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CF61_RS18835	COG5433	transposase activity
CF61_RS18845	COG3209	COG3209 Rhs family protein
CF61_RS18860	COG3157	Type VI secretion system effector, Hcp
CF61_RS18865	COG4104	PAAR repeat-containing protein
CF61_RS18885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CF61_RS18895	COG2226	methyltransferase
CF61_RS18905	COG1388	LysM domain
CF61_RS18905	COG0741	lytic transglycosylase activity
CF61_RS18910	COG2226	methyltransferase
CF61_RS18920	COG0583	DNA-binding transcription factor activity
CF61_RS18925	COG0656	L-ascorbic acid biosynthetic process
CF61_RS18955	COG1464	Belongs to the NlpA lipoprotein family
CF61_RS18965	COG1720	tRNA m6t6A37 methyltransferase activity
CF61_RS18975	COG0791	NLP P60 protein
CF61_RS18980	COG3015	lipoprotein NlpE involved in copper resistance
CF61_RS18985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CF61_RS18990	COG4681	YaeQ
CF61_RS19000	COG4568	rho-dependent transcription termination
CF61_RS19010	COG0346	lactoylglutathione lyase activity
CF61_RS19015	COG1982	Orn Lys Arg decarboxylase major
CF61_RS19025	COG0587	DNA-directed DNA polymerase activity
CF61_RS19050	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CF61_RS19055	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CF61_RS19065	COG0750	zinc metalloprotease
CF61_RS19070	COG0575	Belongs to the CDS family
CF61_RS19075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CF61_RS19080	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CF61_RS19105	COG0024	Methionine aminopeptidase
CF61_RS19120	COG1408	metallophosphoesterase
CF61_RS19130	COG3835	regulator
CF61_RS19135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CF61_RS19150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CF61_RS19155	COG2860	membrane
CF61_RS19175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF61_RS19180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CF61_RS19185	COG1120	ATPase activity
CF61_RS19190	COG4774	siderophore transport
CF61_RS19195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CF61_RS19205	COG1643	Atp-dependent helicase
CF61_RS19210	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CF61_RS19220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CF61_RS19230	COG0617	tRNA 3'-terminal CCA addition
CF61_RS19235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CF61_RS19240	COG1662	PFAM IS1 transposase
CF61_RS19245	COG3539	Fimbrial protein
CF61_RS19250	COG3539	Fimbrial protein
CF61_RS19275	COG5464	transposase or invertase
CF61_RS19285	COG0726	polysaccharide deacetylase
CF61_RS19290	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS19295	COG0842	Transport permease protein
CF61_RS19300	COG1131	(ABC) transporter
CF61_RS19305	COG0288	reversible hydration of carbon dioxide
CF61_RS19310	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CF61_RS19315	COG4993	Dehydrogenase
CF61_RS19320	COG2132	Multicopper oxidase
CF61_RS19345	COG1049	propionate catabolic process, 2-methylcitrate cycle
CF61_RS19350	COG3064	Membrane
CF61_RS19355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF61_RS19360	COG0508	dehydrogenase complex catalyzes the overall conversion of
CF61_RS19365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CF61_RS19370	COG2186	Transcriptional regulator
CF61_RS19380	COG3725	Membrane protein required for beta-lactamase induction
CF61_RS19385	COG3023	N-Acetylmuramoyl-L-alanine amidase
CF61_RS19390	COG0157	Belongs to the NadC ModD family
CF61_RS19400	COG4969	Belongs to the N-Me-Phe pilin family
CF61_RS19405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CF61_RS19410	COG1459	type II secretion system
CF61_RS19420	COG0237	dephospho-CoA kinase activity
CF61_RS19440	COG0494	nUDIX hydrolase
CF61_RS19460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CF61_RS19465	COG0849	cell division
CF61_RS19470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CF61_RS19475	COG1181	Belongs to the D-alanine--D-alanine ligase family
CF61_RS19490	COG0772	Belongs to the SEDS family
CF61_RS19495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CF61_RS19505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CF61_RS19510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CF61_RS19515	COG0768	penicillin binding
CF61_RS19520	COG3116	cell division
CF61_RS19535	COG1609	Transcriptional regulator
CF61_RS19545	COG0440	acetolactate synthase activity
CF61_RS19550	COG0028	Belongs to the TPP enzyme family
CF61_RS19555	COG0583	DNA-binding transcription factor activity
CF61_RS19570	COG0473	3-isopropylmalate dehydrogenase activity
CF61_RS19585	COG2814	Major facilitator Superfamily
CF61_RS19595	COG4533	DNA binding
CF61_RS19600	COG4143	(ABC) transporter
CF61_RS19605	COG1178	ABC-type Fe3 transport system permease component
CF61_RS19615	COG0586	Pfam SNARE associated Golgi protein
CF61_RS19620	COG4977	sequence-specific DNA binding
CF61_RS19635	COG0235	Class ii aldolase
CF61_RS19640	COG0417	DNA replication proofreading
CF61_RS19650	COG0564	pseudouridine synthase activity
CF61_RS19655	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CF61_RS19660	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CF61_RS19665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CF61_RS19690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CF61_RS19705	COG2271	Major facilitator Superfamily
CF61_RS19710	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CF61_RS19715	COG0644	oxidoreductase
CF61_RS19785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CF61_RS19790	COG0505	Belongs to the CarA family
CF61_RS19820	COG1047	Peptidyl-prolyl cis-trans
CF61_RS19835	COG0196	riboflavin kinase activity
CF61_RS19855	COG1662	PFAM IS1 transposase
CF61_RS19860	COG1662	PFAM IS1 transposase
CF61_RS19865	COG3188	usher protein
CF61_RS19875	COG0583	DNA-binding transcription factor activity
CF61_RS19885	COG2963	transposase activity
CF61_RS19890	COG2801	Transposase and inactivated derivatives
CF61_RS19900	COG3385	transposase activity
CF61_RS19920	COG4735	regulation of single-species biofilm formation
CF61_RS19925	COG1584	GPR1 FUN34 yaaH family protein
CF61_RS19930	COG0521	Mo-molybdopterin cofactor biosynthetic process
CF61_RS19940	COG1115	amino acid carrier protein
CF61_RS19960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CF61_RS19970	COG0527	aspartate kinase activity
CF61_RS19970	COG0460	homoserine dehydrogenase
CF61_RS19980	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CF61_RS19990	COG0745	RESPONSE REGULATOR receiver
CF61_RS20000	COG2205	protein histidine kinase activity
CF61_RS20005	COG0745	RESPONSE REGULATOR receiver
CF61_RS20010	COG3045	CreA protein
CF61_RS20015	COG2207	Transcriptional regulator
CF61_RS20015	COG3708	Transcriptional regulator
CF61_RS20035	COG0741	lytic transglycosylase activity
CF61_RS20040	COG0488	(ABC) transporter
CF61_RS20050	COG3172	ATPase kinase involved in NAD metabolism
CF61_RS20050	COG1056	cytidyltransferase-related domain
CF61_RS20055	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CF61_RS20060	COG0560	Phosphoserine phosphatase
CF61_RS20065	COG3726	membrane protein affecting hemolysin expression
CF61_RS20105	COG1328	CTP reductase activity
CF61_RS20110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CF61_RS20115	COG0084	hydrolase, TatD family'
CF61_RS20120	COG4667	esterase of the alpha-beta hydrolase superfamily
CF61_RS20145	COG4772	TonB-dependent receptor
CF61_RS20150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CF61_RS20155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF61_RS20160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF61_RS20165	COG1120	ATPase activity
CF61_RS20170	COG2085	NADP oxidoreductase coenzyme F420-dependent
CF61_RS20185	COG3436	PFAM IS66 Orf2 family protein
CF61_RS20190	COG4372	Transposase
CF61_RS20195	COG2826	transposase and inactivated derivatives, IS30 family
CF61_RS20205	COG1662	PFAM IS1 transposase
CF61_RS20250	COG3842	ATPase activity
CF61_RS20255	COG2040	homocysteine
CF61_RS20260	COG0833	amino acid
CF61_RS20265	COG3039	Transposase
CF61_RS20370	COG2826	transposase and inactivated derivatives, IS30 family
CF61_RS20375	COG2801	Transposase and inactivated derivatives
CF61_RS20455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CF61_RS20540	COG3385	transposase activity
CF61_RS20605	COG1475	DNA binding
CF61_RS20900	COG5001	Diguanylate cyclase
CF61_RS20900	COG3300	MHYT domain
CF61_RS20945	COG1662	PFAM IS1 transposase
CF61_RS20975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CF61_RS20995	COG0697	spore germination
CF61_RS21010	COG1595	DNA-templated transcription, initiation
CF61_RS21015	COG3712	iron ion homeostasis
CF61_RS21020	COG4772	TonB-dependent receptor
CF61_RS21025	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CF61_RS21035	COG1011	Hydrolase
CF61_RS21040	COG0456	acetyltransferase
CF61_RS21045	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CF61_RS21075	COG4114	ferric iron reductase
CF61_RS21080	COG2197	response regulator
CF61_RS21085	COG2197	response regulator
CF61_RS21090	COG2966	Psort location CytoplasmicMembrane, score
CF61_RS21105	COG1484	DNA-dependent DNA replication
CF61_RS21120	COG1063	alcohol dehydrogenase
CF61_RS21125	COG1802	Transcriptional regulator
CF61_RS21130	COG2271	Major facilitator Superfamily
CF61_RS21135	COG0840	transmembrane signaling receptor activity
CF61_RS21140	COG1846	Transcriptional regulator
CF61_RS21145	COG0179	Fumarylacetoacetate (FAA) hydrolase
CF61_RS21150	COG1012	belongs to the aldehyde dehydrogenase family
CF61_RS21155	COG3384	dioxygenase
CF61_RS21165	COG3971	2-oxopent-4-enoate hydratase activity
CF61_RS21185	COG2368	4-hydroxyphenylacetate
CF61_RS21190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CF61_RS21200	COG1966	Carbon starvation protein
CF61_RS21205	COG2879	small protein
CF61_RS21210	COG0523	cobalamin synthesis protein
CF61_RS21215	COG1662	PFAM IS1 transposase
CF61_RS21220	COG2814	Major facilitator Superfamily
CF61_RS21225	COG2733	membrane
CF61_RS21235	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CF61_RS21240	COG1924	4 iron, 4 sulfur cluster binding
CF61_RS21255	COG0477	Major facilitator Superfamily
CF61_RS21265	COG3366	ferrous iron transmembrane transporter activity
CF61_RS21270	COG0700	Nucleoside recognition
CF61_RS21275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CF61_RS21280	COG0583	DNA-binding transcription factor activity
CF61_RS21305	COG2186	Transcriptional regulator
CF61_RS21315	COG0246	Mannitol dehydrogenase
CF61_RS21330	COG2610	gluconate transmembrane transporter activity
CF61_RS21335	COG3539	Fimbrial protein
CF61_RS21365	COG1662	PFAM IS1 transposase
CF61_RS21370	COG1595	DNA-templated transcription, initiation
CF61_RS21375	COG3712	iron ion homeostasis
CF61_RS21380	COG4772	TonB-dependent receptor
CF61_RS21385	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CF61_RS21390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF61_RS21395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CF61_RS21400	COG1120	ATPase activity
CF61_RS21405	COG2085	NADP oxidoreductase coenzyme F420-dependent
CF61_RS21410	COG2963	transposase activity
CF61_RS21430	COG1064	alcohol dehydrogenase
CF61_RS21435	COG0433	COG0433 Predicted ATPase
CF61_RS21440	COG0795	lipopolysaccharide-transporting ATPase activity
CF61_RS21445	COG0795	lipopolysaccharide-transporting ATPase activity
CF61_RS21455	COG2927	DNA polymerase III (CHI subunit)
CF61_RS21465	COG4269	membrane
CF61_RS21470	COG0456	acetyltransferase
CF61_RS21475	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CF61_RS21490	COG2731	YhcH YjgK YiaL family protein
CF61_RS21495	COG1309	transcriptional regulator
CF61_RS21500	COG1028	Short-chain dehydrogenase reductase Sdr
CF61_RS21505	COG0251	oxidation-reduction process
CF61_RS21530	COG0251	oxidation-reduction process
CF61_RS21535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CF61_RS21540	COG1609	Transcriptional regulator
CF61_RS21545	COG1263	PTS System
CF61_RS21545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS21550	COG0366	Alpha amylase catalytic
CF61_RS21555	COG1328	CTP reductase activity
CF61_RS21560	COG0602	queuosine metabolic process
CF61_RS21565	COG3783	Cytochrome b(562)
CF61_RS21570	COG0312	modulator of DNA gyrase
CF61_RS21580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CF61_RS21590	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF61_RS21595	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF61_RS21600	COG1129	ABC transporter
CF61_RS21605	COG1879	ABC-type sugar transport system periplasmic component
CF61_RS21610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CF61_RS21615	COG2105	PFAM AIG2 family protein
CF61_RS21620	COG2911	Protein conserved in bacteria
CF61_RS21625	COG0729	surface antigen
CF61_RS21640	COG1253	flavin adenine dinucleotide binding
CF61_RS21650	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CF61_RS21655	COG1218	3'(2'),5'-bisphosphate nucleotidase
CF61_RS21660	COG0737	Belongs to the 5'-nucleotidase family
CF61_RS21665	COG1733	regulation of RNA biosynthetic process
CF61_RS21670	COG0702	epimerase
CF61_RS21675	COG0697	spore germination
CF61_RS21685	COG1113	amino acid transport
CF61_RS21690	COG0545	Peptidyl-prolyl cis-trans isomerase
CF61_RS21695	COG3061	Opacity-associated protein A
CF61_RS21700	COG1309	transcriptional regulator
CF61_RS21715	COG1024	Enoyl-CoA hydratase
CF61_RS21720	COG4670	ketone body catabolic process
CF61_RS21725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CF61_RS21730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CF61_RS21740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CF61_RS21750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CF61_RS21795	COG3414	Phosphotransferase system galactitol-specific IIB component
CF61_RS21800	COG3037	sugar-specific permease SgaT UlaA
CF61_RS21815	COG1073	alpha beta
CF61_RS21820	COG3650	response to hydrogen peroxide
CF61_RS21830	COG1960	acyl-CoA dehydrogenase activity
CF61_RS21835	COG0754	glutathionylspermidine amidase activity
CF61_RS21840	COG5463	Belongs to the UPF0441 family
CF61_RS21845	COG3766	membrane
CF61_RS21855	COG1842	Phage shock protein A
CF61_RS21860	COG3789	protein conserved in bacteria
CF61_RS21865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CF61_RS21870	COG0557	exoribonuclease II activity
CF61_RS21885	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CF61_RS21890	COG0330	HflC and HflK could
CF61_RS21895	COG0330	HflC and HflK could
CF61_RS21900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CF61_RS21920	COG0860	N-Acetylmuramoyl-L-alanine amidase
CF61_RS21925	COG0802	atpase or kinase
CF61_RS21930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CF61_RS21930	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CF61_RS21935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CF61_RS21970	COG1511	domain protein
CF61_RS21970	COG3264	Mechanosensitive ion channel
CF61_RS21985	COG0531	amino acid
CF61_RS21995	COG1053	succinate dehydrogenase
CF61_RS22000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CF61_RS22015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CF61_RS22020	COG3040	lipid binding
CF61_RS22025	COG2076	Multidrug Resistance protein
CF61_RS22030	COG5510	response to toxic substance
CF61_RS22035	COG5510	response to toxic substance
CF61_RS22045	COG1509	lysine 2,3-aminomutase activity
CF61_RS22070	COG0531	amino acid
CF61_RS22075	COG3030	protein affecting phage T7 exclusion by the F plasmid
CF61_RS22080	COG1027	Aspartate ammonia-lyase
CF61_RS22085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CF61_RS22095	COG4232	protein-disulfide reductase activity
CF61_RS22100	COG1309	transcriptional regulator
CF61_RS22110	COG3710	Transcriptional regulator
CF61_RS22115	COG0531	amino acid
CF61_RS22120	COG1982	Orn Lys Arg decarboxylase major
CF61_RS22125	COG3104	oligopeptide transport
CF61_RS22130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CF61_RS22145	COG2388	GCN5-related N-acetyl-transferase
CF61_RS22150	COG3592	Divergent 4Fe-4S mono-cluster
CF61_RS22155	COG3290	protein histidine kinase activity
CF61_RS22160	COG4565	transcriptional regulatory protein
CF61_RS22170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CF61_RS22175	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CF61_RS22175	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CF61_RS22180	COG3647	Membrane
CF61_RS22185	COG2211	Major facilitator Superfamily
CF61_RS22190	COG1486	melibiose metabolic process
CF61_RS22200	COG2169	Transcriptional regulator
CF61_RS22205	COG1982	Orn Lys Arg decarboxylase major
CF61_RS22210	COG2207	Transcriptional regulator
CF61_RS22215	COG1662	PFAM IS1 transposase
CF61_RS22220	COG0531	amino acid
CF61_RS22225	COG2194	sulfuric ester hydrolase activity
CF61_RS22230	COG0745	RESPONSE REGULATOR receiver
CF61_RS22235	COG0642	Histidine kinase
CF61_RS22245	COG0477	Major facilitator Superfamily
CF61_RS22260	COG2824	Alkylphosphonate utilization operon protein PhnA
CF61_RS22265	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CF61_RS22275	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CF61_RS22280	COG3639	organic phosphonate transmembrane transporter activity
CF61_RS22285	COG2188	Transcriptional regulator
CF61_RS22290	COG3624	Phosphonate C-P lyase system protein PhnG
CF61_RS22295	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CF61_RS22300	COG3626	phosphonate metabolism
CF61_RS22305	COG3627	carbon phosphorus lyase activity
CF61_RS22310	COG4107	phosphonate C-P lyase system protein PhnK
CF61_RS22315	COG4778	phosphonate C-P lyase system protein PhnL
CF61_RS22320	COG3454	Phosphonate metabolism
CF61_RS22325	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CF61_RS22330	COG0456	acetyltransferase
CF61_RS22335	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CF61_RS22345	COG0698	ribose 5-phosphate isomerase
CF61_RS22350	COG1737	Transcriptional regulator
CF61_RS22355	COG1879	ABC-type sugar transport system periplasmic component
CF61_RS22360	COG1129	ABC transporter
CF61_RS22365	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF61_RS22370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CF61_RS22375	COG1940	carbohydrate kinase activity
CF61_RS22380	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CF61_RS22390	COG1566	PFAM secretion protein HlyD family protein
CF61_RS22395	COG1289	transmembrane transporter activity
CF61_RS22400	COG1538	Outer membrane efflux protein
CF61_RS22405	COG3383	formate dehydrogenase (NAD+) activity
CF61_RS22410	COG3383	formate dehydrogenase (NAD+) activity
CF61_RS22415	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CF61_RS22420	COG1301	dicarboxylic acid transport
CF61_RS22425	COG4235	cytochrome complex assembly
CF61_RS22430	COG3088	subunit of a heme lyase
CF61_RS22435	COG1138	Cytochrome C-type biogenesis protein
CF61_RS22440	COG3301	Polysulphide reductase, NrfD
CF61_RS22445	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS22450	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CF61_RS22460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CF61_RS22465	COG3162	membrane
CF61_RS22475	COG1357	PFAM Pentapeptide repeats (8 copies)
CF61_RS22480	COG0025	NhaP-type Na H and K H
CF61_RS22485	COG2252	PERMEase
CF61_RS22490	COG0789	Transcriptional regulator
CF61_RS22495	COG2207	Transcriptional regulator
CF61_RS22500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CF61_RS22510	COG0629	single-stranded DNA binding
CF61_RS22515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CF61_RS22520	COG2315	Protein conserved in bacteria
CF61_RS22530	COG3700	Belongs to the class B bacterial acid phosphatase family
CF61_RS22540	COG1448	Aminotransferase
CF61_RS22545	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CF61_RS22550	COG0305	Participates in initiation and elongation during chromosome replication
CF61_RS22555	COG0604	alcohol dehydrogenase
CF61_RS22565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CF61_RS22580	COG0735	belongs to the Fur family
CF61_RS22585	COG3237	CsbD-like
CF61_RS22590	COG0534	Mate efflux family protein
CF61_RS22600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CF61_RS22620	COG1357	PFAM Pentapeptide repeats (8 copies)
CF61_RS22640	COG3842	ATPase activity
CF61_RS22650	COG2182	Extracellular solute-binding protein
CF61_RS22655	COG1175	transmembrane transport
CF61_RS22660	COG3833	ABC-type maltose transport systems, permease component
CF61_RS22665	COG2814	Major facilitator Superfamily
CF61_RS22665	COG0477	Major facilitator Superfamily
CF61_RS22690	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF61_RS22715	COG0527	aspartate kinase activity
CF61_RS22725	COG1187	pseudouridine synthase activity
CF61_RS22735	COG1283	sodium-dependent phosphate transmembrane transporter activity
CF61_RS22740	COG1410	methionine synthase
CF61_RS22740	COG0646	methionine synthase
CF61_RS22745	COG1414	Transcriptional regulator
CF61_RS22760	COG2224	Isocitrate lyase
CF61_RS22765	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CF61_RS22775	COG0456	acetyltransferase
CF61_RS22805	COG0151	Belongs to the GarS family
CF61_RS22810	COG2204	response regulator
CF61_RS22815	COG4191	Histidine kinase
CF61_RS22820	COG3678	ATP-independent chaperone mediated protein folding
CF61_RS22835	COG3068	Protein conserved in bacteria
CF61_RS22870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CF61_RS22875	COG2104	thiamine diphosphate biosynthetic process
CF61_RS22885	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CF61_RS22925	COG0250	Participates in transcription elongation, termination and antitermination
CF61_RS22930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CF61_RS22970	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CF61_RS22970	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CF61_RS23000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CF61_RS23005	COG4206	TonB-dependent receptor
CF61_RS23030	COG0583	DNA-binding transcription factor activity
CF61_RS23045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CF61_RS23065	COG2194	sulfuric ester hydrolase activity
CF61_RS23070	COG2207	Transcriptional regulator
CF61_RS23080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS23085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CF61_RS23090	COG1882	Formate acetyltransferase
CF61_RS23095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS23100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS23105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS23105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS23105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CF61_RS23110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CF61_RS23115	COG0371	Dehydrogenase
CF61_RS23130	COG0697	spore germination
CF61_RS23140	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CF61_RS23150	COG0460	homoserine dehydrogenase
CF61_RS23150	COG0527	aspartate kinase activity
CF61_RS23155	COG0626	cystathionine gamma-synthase activity
CF61_RS23165	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CF61_RS23190	COG3209	COG3209 Rhs family protein
CF61_RS23190	COG3209	COG3209 Rhs family protein
CF61_RS23200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CF61_RS23205	COG1609	Transcriptional regulator
CF61_RS23210	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CF61_RS23225	COG1575	Belongs to the MenA family. Type 1 subfamily
CF61_RS23240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CF61_RS23250	COG1494	fructose-1,6-bisphosphatase
CF61_RS23255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CF61_RS23260	COG0589	response to stress
CF61_RS23265	COG3691	Protein conserved in bacteria
CF61_RS23270	COG3152	Membrane
CF61_RS23290	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CF61_RS23305	COG3678	ATP-independent chaperone mediated protein folding
CF61_RS23310	COG0745	RESPONSE REGULATOR receiver
CF61_RS23315	COG2205	protein histidine kinase activity
CF61_RS23320	COG2258	MOSC domain
CF61_RS23335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CF61_RS23385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS23390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS23390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CF61_RS23395	COG1363	Peptidase, m42
CF61_RS23400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CF61_RS23400	COG3711	transcriptional antiterminator
CF61_RS23415	COG3383	formate dehydrogenase (NAD+) activity
CF61_RS23415	COG0243	molybdopterin cofactor binding
CF61_RS23420	COG3383	formate dehydrogenase (NAD+) activity
CF61_RS23420	COG0243	molybdopterin cofactor binding
CF61_RS23425	COG0437	4 iron, 4 sulfur cluster binding
CF61_RS23430	COG2864	formate dehydrogenase
CF61_RS23445	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CF61_RS23450	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CF61_RS23455	COG0456	acetyltransferase
CF61_RS23470	COG1011	Hydrolase
CF61_RS23475	COG1349	DNA-binding transcription factor activity
CF61_RS23480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF61_RS23485	COG2084	Dehydrogenase
CF61_RS23490	COG3684	Belongs to the aldolase LacD family
CF61_RS23495	COG2942	2-epimerase
CF61_RS23500	COG2017	converts alpha-aldose to the beta-anomer
CF61_RS23510	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CF61_RS23515	COG2271	Major facilitator Superfamily
CF61_RS23520	COG1082	Xylose isomerase domain protein TIM barrel
CF61_RS23525	COG2188	Transcriptional regulator
CF61_RS23530	COG1217	gtp-binding protein TYPA
CF61_RS23540	COG0174	glutamine synthetase
CF61_RS23545	COG3852	Histidine kinase
CF61_RS23550	COG2204	response regulator
CF61_RS23560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CF61_RS23575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CF61_RS23575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CF61_RS23585	COG0204	Acyl-transferase
CF61_RS23590	COG5339	Protein conserved in bacteria
CF61_RS23595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CF61_RS23600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CF61_RS23605	COG3084	Protein conserved in bacteria
CF61_RS23610	COG0746	molybdenum cofactor guanylyltransferase activity
CF61_RS23615	COG1763	Mo-molybdopterin cofactor biosynthetic process
CF61_RS23645	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CF61_RS23650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CF61_RS23655	COG1739	Uncharacterized protein family UPF0029
CF61_RS23670	COG0183	Belongs to the thiolase family
CF61_RS23675	COG0543	2 iron, 2 sulfur cluster binding
CF61_RS23680	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CF61_RS23685	COG0250	Participates in transcription elongation, termination and antitermination
CF61_RS23690	COG0084	hydrolase, TatD family'
CF61_RS23695	COG0805	protein transport
CF61_RS23700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CF61_RS23705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CF61_RS23715	COG3165	ubiquinone biosynthetic process from chorismate
CF61_RS23725	COG1322	Protein conserved in bacteria
CF61_RS23730	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CF61_RS23735	COG0412	Dienelactone hydrolase
CF61_RS23745	COG0583	DNA-binding transcription factor activity
CF61_RS23750	COG0697	spore germination
CF61_RS23755	COG0561	phosphatase activity
CF61_RS23760	COG2267	carboxylic ester hydrolase activity
CF61_RS23765	COG1280	lysine exporter protein (LysE YggA)
CF61_RS23770	COG1280	lysine exporter protein (LysE YggA)
CF61_RS23775	COG0514	ATP-dependent DNA helicase (RecQ)
CF61_RS23780	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CF61_RS23785	COG2050	protein possibly involved in aromatic compounds catabolism
CF61_RS23790	COG2962	Rard protein
CF61_RS23805	COG0598	Magnesium transport protein CorA
CF61_RS23810	COG3698	Phosphodiester glycosidase
CF61_RS23815	COG0210	DNA helicase
CF61_RS23820	COG1011	Hydrolase
CF61_RS23830	COG3159	Protein conserved in bacteria
CF61_RS23840	COG5567	small periplasmic lipoprotein
CF61_RS23850	COG3072	Adenylate cyclase
CF61_RS23860	COG1587	Uroporphyrinogen-III synthase
CF61_RS23865	COG2959	enzyme of heme biosynthesis
CF61_RS23870	COG3071	HemY protein
CF61_RS23875	COG3119	arylsulfatase activity
CF61_RS23880	COG0641	radical SAM
CF61_RS23905	COG1113	amino acid transport
CF61_RS23925	COG2244	polysaccharide biosynthetic process
CF61_RS23930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CF61_RS23935	COG0456	acetyltransferase
CF61_RS23940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CF61_RS23945	COG1088	dTDP-glucose 4,6-dehydratase activity
CF61_RS23950	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CF61_RS23955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CF61_RS23960	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CF61_RS23965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CF61_RS23975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CF61_RS23985	COG3118	belongs to the thioredoxin family
CF61_RS24000	COG0210	DNA helicase
CF61_RS24020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CF61_RS24030	COG0583	DNA-binding transcription factor activity
CF61_RS24035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CF61_RS24045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CF61_RS24050	COG3978	acetolactate synthase activity
CF61_RS24065	COG0606	chelatase, subunit chli
CF61_RS24070	COG3085	chromosome segregation
CF61_RS24120	COG2186	Transcriptional regulator
CF61_RS24125	COG0477	Major facilitator Superfamily
CF61_RS24130	COG1609	Transcriptional regulator
CF61_RS24135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CF61_RS24140	COG1879	ABC-type sugar transport system periplasmic component
CF61_RS24145	COG1172	Belongs to the binding-protein-dependent transport system permease family
CF61_RS24150	COG1129	ABC transporter
CF61_RS24180	COG1522	sequence-specific DNA binding
CF61_RS24185	COG0716	FMN binding
CF61_RS24200	COG3312	ion transport
CF61_RS24255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CF61_RS24260	COG0573	inorganic phosphate transmembrane transporter activity
CF61_RS24265	COG0581	inorganic phosphate transmembrane transporter activity
CF61_RS24270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CF61_RS24275	COG0704	Plays a role in the regulation of phosphate uptake
CF61_RS24280	COG3711	transcriptional antiterminator
CF61_RS24285	COG1263	PTS System
CF61_RS24285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CF61_RS24285	COG2190	(PTS) system
CF61_RS24290	COG2723	6-phospho-beta-galactosidase activity
CF61_RS24300	COG2382	esterase
CF61_RS24305	COG0363	glucosamine-6-phosphate deaminase activity
CF61_RS24310	COG3196	Protein conserved in bacteria
CF61_RS24325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CF61_RS24330	COG2252	PERMEase
CF61_RS24335	COG0431	NADPH-dependent FMN reductase
CF61_RS24340	COG2091	lysine biosynthetic process via aminoadipic acid
CF61_RS24355	COG0814	amino acid
CF61_RS24460	COG0534	Mate efflux family protein
CF61_RS24465	COG0534	Mate efflux family protein
CF61_RS24470	COG3209	COG3209 Rhs family protein