locus-tag	class	description
U14A_RS00010	COG0460	homoserine dehydrogenase
U14A_RS00010	COG0527	aspartate kinase activity
U14A_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
U14A_RS00035	COG1115	amino acid carrier protein
U14A_RS00045	COG0521	Mo-molybdopterin cofactor biosynthetic process
U14A_RS00050	COG1584	GPR1 FUN34 yaaH family protein
U14A_RS00055	COG4735	regulation of single-species biofilm formation
U14A_RS00085	COG3119	arylsulfatase activity
U14A_RS00100	COG0583	DNA-binding transcription factor activity
U14A_RS00125	COG0196	riboflavin kinase activity
U14A_RS00140	COG1047	Peptidyl-prolyl cis-trans
U14A_RS00165	COG0505	Belongs to the CarA family
U14A_RS00170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
U14A_RS00220	COG0644	oxidoreductase
U14A_RS00225	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
U14A_RS00230	COG2271	Major facilitator Superfamily
U14A_RS00245	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
U14A_RS00275	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
U14A_RS00280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U14A_RS00290	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
U14A_RS00295	COG0564	pseudouridine synthase activity
U14A_RS00305	COG0417	DNA replication proofreading
U14A_RS00310	COG0235	Class ii aldolase
U14A_RS00325	COG4977	sequence-specific DNA binding
U14A_RS00330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS00335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U14A_RS00340	COG3181	Tripartite tricarboxylate transporter family receptor
U14A_RS00355	COG0586	Pfam SNARE associated Golgi protein
U14A_RS00365	COG1178	ABC-type Fe3 transport system permease component
U14A_RS00370	COG4143	(ABC) transporter
U14A_RS00410	COG0583	DNA-binding transcription factor activity
U14A_RS00415	COG0028	Belongs to the TPP enzyme family
U14A_RS00420	COG0440	acetolactate synthase activity
U14A_RS00430	COG1609	Transcriptional regulator
U14A_RS00445	COG3116	cell division
U14A_RS00450	COG0768	penicillin binding
U14A_RS00455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
U14A_RS00460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
U14A_RS00475	COG0772	Belongs to the SEDS family
U14A_RS00490	COG1181	Belongs to the D-alanine--D-alanine ligase family
U14A_RS00495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
U14A_RS00500	COG0849	cell division
U14A_RS00505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
U14A_RS00525	COG0494	nUDIX hydrolase
U14A_RS00540	COG0237	dephospho-CoA kinase activity
U14A_RS00550	COG1459	type II secretion system
U14A_RS00560	COG4969	Belongs to the N-Me-Phe pilin family
U14A_RS00565	COG0157	Belongs to the NadC ModD family
U14A_RS00570	COG3023	N-Acetylmuramoyl-L-alanine amidase
U14A_RS00575	COG3725	Membrane protein required for beta-lactamase induction
U14A_RS00580	COG1113	amino acid transport
U14A_RS00585	COG3157	Type VI secretion system effector, Hcp
U14A_RS00625	COG2186	Transcriptional regulator
U14A_RS00630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
U14A_RS00635	COG0508	dehydrogenase complex catalyzes the overall conversion of
U14A_RS00640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U14A_RS00645	COG3064	Membrane
U14A_RS00645	COG3064	Membrane
U14A_RS00650	COG1049	propionate catabolic process, 2-methylcitrate cycle
U14A_RS00675	COG2132	Multicopper oxidase
U14A_RS00680	COG4993	Dehydrogenase
U14A_RS00685	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
U14A_RS00690	COG0288	reversible hydration of carbon dioxide
U14A_RS00695	COG1131	(ABC) transporter
U14A_RS00700	COG0842	Transport permease protein
U14A_RS00705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS00710	COG0726	polysaccharide deacetylase
U14A_RS00720	COG5464	transposase or invertase
U14A_RS00725	COG5464	transposase or invertase
U14A_RS00730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
U14A_RS00740	COG3539	Fimbrial protein
U14A_RS00745	COG3539	Fimbrial protein
U14A_RS00750	COG3539	Fimbrial protein
U14A_RS00755	COG3539	Fimbrial protein
U14A_RS00760	COG3188	usher protein
U14A_RS00765	COG3121	Chaperone
U14A_RS00770	COG3539	Fimbrial protein
U14A_RS00775	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
U14A_RS00780	COG0617	tRNA 3'-terminal CCA addition
U14A_RS00785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
U14A_RS00790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U14A_RS00800	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
U14A_RS00805	COG1643	Atp-dependent helicase
U14A_RS00810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U14A_RS00820	COG3121	Chaperone
U14A_RS00835	COG4774	siderophore transport
U14A_RS00840	COG1120	ATPase activity
U14A_RS00845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U14A_RS00850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS00875	COG2860	membrane
U14A_RS00880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U14A_RS00895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U14A_RS00900	COG3835	regulator
U14A_RS00920	COG0024	Methionine aminopeptidase
U14A_RS00945	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
U14A_RS00950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
U14A_RS00955	COG0575	Belongs to the CDS family
U14A_RS00960	COG0750	zinc metalloprotease
U14A_RS00970	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
U14A_RS00975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
U14A_RS01000	COG0587	DNA-directed DNA polymerase activity
U14A_RS01010	COG1982	Orn Lys Arg decarboxylase major
U14A_RS01015	COG0346	lactoylglutathione lyase activity
U14A_RS01020	COG0037	tRNA processing
U14A_RS01025	COG4568	rho-dependent transcription termination
U14A_RS01035	COG4681	YaeQ
U14A_RS01040	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
U14A_RS01045	COG3015	lipoprotein NlpE involved in copper resistance
U14A_RS01050	COG0791	NLP P60 protein
U14A_RS01060	COG1720	tRNA m6t6A37 methyltransferase activity
U14A_RS01070	COG1464	Belongs to the NlpA lipoprotein family
U14A_RS01075	COG2011	ABC-type metal ion transport system permease component
U14A_RS01080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
U14A_RS01085	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
U14A_RS01120	COG0656	L-ascorbic acid biosynthetic process
U14A_RS01125	COG0583	DNA-binding transcription factor activity
U14A_RS01135	COG2226	methyltransferase
U14A_RS01140	COG1388	LysM domain
U14A_RS01140	COG0741	lytic transglycosylase activity
U14A_RS01150	COG2226	methyltransferase
U14A_RS01160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
U14A_RS01170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
U14A_RS01180	COG1960	acyl-CoA dehydrogenase activity
U14A_RS01190	COG0121	glutamine amidotransferase
U14A_RS01195	COG3034	peptidoglycan biosynthetic process
U14A_RS01200	COG0791	NLP P60 protein
U14A_RS01205	COG1943	Transposase
U14A_RS01225	COG1987	bacterial-type flagellum assembly
U14A_RS01250	COG1677	Flagellar hook-basal body complex protein FliE
U14A_RS01260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U14A_RS01280	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
U14A_RS01300	COG0463	Glycosyl transferase, family 2
U14A_RS01325	COG1815	bacterial-type flagellum-dependent cell motility
U14A_RS01330	COG1558	bacterial-type flagellum-dependent cell motility
U14A_RS01340	COG1749	Flagellar hook protein flgE
U14A_RS01345	COG4787	bacterial-type flagellum-dependent cell motility
U14A_RS01350	COG4786	Flagellar basal body rod
U14A_RS01375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
U14A_RS01390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
U14A_RS01400	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
U14A_RS01425	COG1191	sigma factor activity
U14A_RS01430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
U14A_RS01445	COG0454	-acetyltransferase
U14A_RS01450	COG1690	Belongs to the RtcB family
U14A_RS01455	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
U14A_RS01460	COG2195	Cleaves the N-terminal amino acid of tripeptides
U14A_RS01480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
U14A_RS01520	COG0732	type I restriction modification DNA specificity domain
U14A_RS01560	COG3477	response to acidic pH
U14A_RS01570	COG0727	PFAM Uncharacterised protein family (UPF0153)
U14A_RS01630	COG1902	pentaerythritol trinitrate reductase activity
U14A_RS01635	COG1073	alpha beta
U14A_RS01640	COG0583	DNA-binding transcription factor activity
U14A_RS01650	COG0667	Aldo Keto reductase
U14A_RS01655	COG0656	L-ascorbic acid biosynthetic process
U14A_RS01660	COG1388	LysM domain
U14A_RS01660	COG2373	Large extracellular alpha-helical protein
U14A_RS01660	COG4932	domain protein
U14A_RS01670	COG2207	Transcriptional regulator
U14A_RS01670	COG3708	Transcriptional regulator
U14A_RS01675	COG0656	L-ascorbic acid biosynthetic process
U14A_RS01680	COG3059	membrane
U14A_RS01690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U14A_RS01695	COG2207	Transcriptional regulator
U14A_RS01700	COG0247	lactate metabolic process
U14A_RS01705	COG1139	Iron-sulfur cluster binding protein
U14A_RS01710	COG1556	Lactate utilization protein
U14A_RS01720	COG3468	outer membrane autotransporter barrel domain protein
U14A_RS01735	COG2200	EAL domain
U14A_RS01735	COG2771	luxR family
U14A_RS01740	COG0582	viral genome integration into host DNA
U14A_RS01755	COG1012	belongs to the aldehyde dehydrogenase family
U14A_RS01765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
U14A_RS01770	COG2771	luxR family
U14A_RS01770	COG2200	EAL domain
U14A_RS01775	COG0583	DNA-binding transcription factor activity
U14A_RS01785	COG0666	response to abiotic stimulus
U14A_RS01795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
U14A_RS01800	COG1304	FMN binding
U14A_RS01805	COG0549	Belongs to the carbamate kinase family
U14A_RS01810	COG0402	S-adenosylhomocysteine deaminase activity
U14A_RS01815	COG1064	alcohol dehydrogenase
U14A_RS01825	COG1280	lysine exporter protein (LysE YggA)
U14A_RS01835	COG3829	transcription factor binding
U14A_RS01840	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
U14A_RS01845	COG0372	Belongs to the citrate synthase family
U14A_RS01850	COG2079	MmgE PrpD family protein
U14A_RS01855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
U14A_RS01860	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
U14A_RS01865	COG0402	S-adenosylhomocysteine deaminase activity
U14A_RS01870	COG0110	maltose O-acetyltransferase activity
U14A_RS01875	COG2223	nitrite transmembrane transporter activity
U14A_RS01885	COG1609	Transcriptional regulator
U14A_RS01890	COG1414	Transcriptional regulator
U14A_RS01920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
U14A_RS01925	COG2814	Major facilitator Superfamily
U14A_RS01930	COG3122	Protein conserved in bacteria
U14A_RS01950	COG4521	taurine ABC transporter
U14A_RS01960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U14A_RS01965	COG2175	clavaminate synthase activity
U14A_RS01970	COG0113	porphobilinogen synthase activity
U14A_RS01975	COG3468	outer membrane autotransporter barrel domain protein
U14A_RS01980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U14A_RS01985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U14A_RS01990	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
U14A_RS02010	COG1181	Belongs to the D-alanine--D-alanine ligase family
U14A_RS02020	COG1785	Belongs to the alkaline phosphatase family
U14A_RS02030	COG3706	GGDEF domain
U14A_RS02035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
U14A_RS02055	COG4126	flavin adenine dinucleotide binding
U14A_RS02080	COG1940	carbohydrate kinase activity
U14A_RS02085	COG2814	Major facilitator Superfamily
U14A_RS02090	COG0419	ATPase involved in DNA repair
U14A_RS02095	COG0420	3'-5' exonuclease activity
U14A_RS02100	COG0745	RESPONSE REGULATOR receiver
U14A_RS02105	COG5002	protein histidine kinase activity
U14A_RS02110	COG1114	Component of the transport system for branched-chain amino acids
U14A_RS02115	COG1113	amino acid transport
U14A_RS02120	COG0366	Alpha amylase catalytic
U14A_RS02140	COG1862	Preprotein translocase
U14A_RS02145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
U14A_RS02150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
U14A_RS02155	COG1403	HNH endonuclease
U14A_RS02160	COG3248	Nucleoside-binding outer membrane protein
U14A_RS02165	COG4238	major outer membrane lipoprotein
U14A_RS02175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
U14A_RS02175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
U14A_RS02190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
U14A_RS02195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
U14A_RS02200	COG0667	Aldo Keto reductase
U14A_RS02210	COG0142	geranyltranstransferase activity
U14A_RS02225	COG0693	protein deglycase activity
U14A_RS02230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
U14A_RS02240	COG2814	Major facilitator Superfamily
U14A_RS02250	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
U14A_RS02255	COG1845	cytochrome c oxidase, subunit III
U14A_RS02260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
U14A_RS02265	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
U14A_RS02270	COG2223	nitrite transmembrane transporter activity
U14A_RS02275	COG3056	Lipoprotein
U14A_RS02280	COG0271	Belongs to the BolA IbaG family
U14A_RS02300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
U14A_RS02305	COG0776	regulation of translation
U14A_RS02310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U14A_RS02315	COG1555	photosystem II stabilization
U14A_RS02320	COG0824	Thioesterase
U14A_RS02330	COG4533	DNA binding
U14A_RS02340	COG1522	sequence-specific DNA binding
U14A_RS02345	COG1132	(ABC) transporter
U14A_RS02350	COG1132	(ABC) transporter
U14A_RS02355	COG0347	Belongs to the P(II) protein family
U14A_RS02360	COG0004	ammonium transporteR
U14A_RS02365	COG1946	Acyl-CoA thioesterase
U14A_RS02370	COG3126	Type III secretion system lipoprotein chaperone (YscW)
U14A_RS02375	COG3695	enzyme binding
U14A_RS02385	COG5507	3-demethylubiquinone-9 3-methyltransferase
U14A_RS02390	COG4943	cyclic-guanylate-specific phosphodiesterase activity
U14A_RS02400	COG0110	maltose O-acetyltransferase activity
U14A_RS02415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U14A_RS02420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U14A_RS02425	COG1309	transcriptional regulator
U14A_RS02430	COG1196	nuclear chromosome segregation
U14A_RS02430	COG3264	Mechanosensitive ion channel
U14A_RS02440	COG3923	Primosomal replication protein n
U14A_RS02445	COG2832	Protein of unknown function (DUF454)
U14A_RS02455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
U14A_RS02490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS02495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
U14A_RS02495	COG4651	solute:proton antiporter activity
U14A_RS02500	COG2223	nitrite transmembrane transporter activity
U14A_RS02505	COG0737	Belongs to the 5'-nucleotidase family
U14A_RS02520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
U14A_RS02525	COG3735	TraB family
U14A_RS02530	COG3549	Plasmid maintenance system killer
U14A_RS02535	COG3093	addiction module antidote protein HigA
U14A_RS02540	COG2217	Heavy metal translocating P-type atpase
U14A_RS02545	COG2066	Belongs to the glutaminase family
U14A_RS02550	COG0531	amino acid
U14A_RS02555	COG0789	Transcriptional regulator
U14A_RS02565	COG1585	Membrane protein implicated in regulation of membrane protease activity
U14A_RS02570	COG0330	HflC and HflK could
U14A_RS02575	COG4619	ABC transporter
U14A_RS02580	COG0390	transport system, permease component
U14A_RS02585	COG3118	belongs to the thioredoxin family
U14A_RS02590	COG0300	oxidoreductase activity
U14A_RS02595	COG2755	lipolytic protein G-D-S-L family
U14A_RS02600	COG4181	ATPase activity
U14A_RS02605	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
U14A_RS02610	COG3157	Type VI secretion system effector, Hcp
U14A_RS02650	COG3960	tartronate-semialdehyde synthase activity
U14A_RS02655	COG3622	Belongs to the hyi family
U14A_RS02660	COG2084	Dehydrogenase
U14A_RS02665	COG1953	Uracil, thiamine, allantoin
U14A_RS02675	COG2233	PERMEase
U14A_RS02680	COG1929	Belongs to the glycerate kinase type-1 family
U14A_RS02685	COG3257	ureidoglycine aminohydrolase activity
U14A_RS02690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
U14A_RS02695	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
U14A_RS02700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
U14A_RS02705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
U14A_RS02715	COG0549	Belongs to the carbamate kinase family
U14A_RS02720	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
U14A_RS02725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
U14A_RS02740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
U14A_RS02750	COG1988	membrane-bound metal-dependent
U14A_RS02755	COG2501	S4 domain
U14A_RS02785	COG0500	methyltransferase
U14A_RS02790	COG4571	Outer membrane protease
U14A_RS02800	COG4783	chaperone-mediated protein folding
U14A_RS02805	COG1215	transferase activity, transferring glycosyl groups
U14A_RS02810	COG5002	protein histidine kinase activity
U14A_RS02815	COG0745	RESPONSE REGULATOR receiver
U14A_RS02820	COG1538	Outer membrane efflux protein
U14A_RS02825	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U14A_RS02830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U14A_RS02835	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U14A_RS02840	COG1113	amino acid transport
U14A_RS02845	COG0668	transmembrane transport
U14A_RS02850	COG0778	Nitroreductase
U14A_RS02855	COG2315	Protein conserved in bacteria
U14A_RS02885	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS02895	COG1172	Belongs to the binding-protein-dependent transport system permease family
U14A_RS02900	COG1129	ABC transporter
U14A_RS02910	COG1879	ABC-type sugar transport system periplasmic component
U14A_RS02915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
U14A_RS02920	COG2390	Transcriptional regulator
U14A_RS02925	COG3959	Transketolase, thiamine diphosphate binding domain
U14A_RS02930	COG3958	Transketolase
U14A_RS02935	COG2977	Belongs to the P-Pant transferase superfamily
U14A_RS02940	COG4771	TonB-dependent receptor
U14A_RS02945	COG2382	esterase
U14A_RS02950	COG3251	PFAM MbtH domain protein
U14A_RS02955	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
U14A_RS02955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U14A_RS02965	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
U14A_RS02970	COG1120	ATPase activity
U14A_RS02975	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS02980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS02990	COG4592	Periplasmic binding protein
U14A_RS02995	COG1169	isochorismate synthase
U14A_RS03000	COG1021	2,3-dihydroxybenzoate-AMP ligase
U14A_RS03005	COG3433	isochorismatase activity
U14A_RS03005	COG1535	isochorismatase
U14A_RS03010	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS03015	COG2050	protein possibly involved in aromatic compounds catabolism
U14A_RS03020	COG1966	Carbon starvation protein
U14A_RS03025	COG2879	small protein
U14A_RS03030	COG0371	Dehydrogenase
U14A_RS03035	COG0436	Aminotransferase
U14A_RS03040	COG1475	DNA binding
U14A_RS03045	COG3969	phosphoadenosine phosphosulfate
U14A_RS03050	COG0583	DNA-binding transcription factor activity
U14A_RS03055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
U14A_RS03060	COG0450	alkyl hydroperoxide reductase
U14A_RS03065	COG3634	alkyl hydroperoxide reductase activity
U14A_RS03070	COG0589	response to stress
U14A_RS03075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
U14A_RS03080	COG3719	Belongs to the RNase T2 family
U14A_RS03085	COG0471	metal ion transport
U14A_RS03100	COG3051	citrate lyase alpha subunit
U14A_RS03105	COG2301	Belongs to the HpcH HpaI aldolase family
U14A_RS03115	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
U14A_RS03120	COG3290	protein histidine kinase activity
U14A_RS03125	COG4565	transcriptional regulatory protein
U14A_RS03130	COG3069	C4-dicarboxylate transmembrane transporter activity
U14A_RS03150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
U14A_RS03155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
U14A_RS03180	COG1686	Belongs to the peptidase S11 family
U14A_RS03185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
U14A_RS03190	COG0772	Belongs to the SEDS family
U14A_RS03195	COG0768	penicillin binding
U14A_RS03205	COG0799	negative regulation of ribosome biogenesis
U14A_RS03210	COG0406	alpha-ribazole phosphatase activity
U14A_RS03220	COG1466	dna polymerase III delta subunit
U14A_RS03235	COG2888	peptidyl-tyrosine sulfation
U14A_RS03245	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
U14A_RS03260	COG2214	Heat shock protein DnaJ domain protein
U14A_RS03265	COG0443	Heat shock 70 kDa protein
U14A_RS03275	COG1126	abc transporter atp-binding protein
U14A_RS03280	COG0765	amino acid transport
U14A_RS03285	COG0765	amino acid transport
U14A_RS03290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U14A_RS03300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
U14A_RS03305	COG4535	Mg2 and Co2 transporter CorC
U14A_RS03315	COG1702	phosphate starvation-inducible protein PhoH
U14A_RS03325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
U14A_RS03370	COG0367	asparagine synthase
U14A_RS03375	COG0647	UMP catabolic process
U14A_RS03380	COG1940	carbohydrate kinase activity
U14A_RS03380	COG1846	Transcriptional regulator
U14A_RS03385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
U14A_RS03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS03395	COG1263	PTS System
U14A_RS03395	COG2190	(PTS) system
U14A_RS03415	COG0861	Integral membrane protein TerC family
U14A_RS03420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U14A_RS03430	COG3395	kinase activity
U14A_RS03435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
U14A_RS03440	COG1349	DNA-binding transcription factor activity
U14A_RS03460	COG0735	belongs to the Fur family
U14A_RS03470	COG0716	FMN binding
U14A_RS03480	COG0596	Alpha beta hydrolase
U14A_RS03485	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
U14A_RS03490	COG0033	Phosphoglucomutase
U14A_RS03495	COG0531	amino acid
U14A_RS03500	COG1982	Orn Lys Arg decarboxylase major
U14A_RS03515	COG0745	RESPONSE REGULATOR receiver
U14A_RS03520	COG2205	protein histidine kinase activity
U14A_RS03550	COG3272	Protein of unknown function (DUF1722)
U14A_RS03555	COG0415	Belongs to the DNA photolyase family
U14A_RS03565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
U14A_RS03570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
U14A_RS03575	COG1984	allophanate hydrolase subunit 2
U14A_RS03580	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
U14A_RS03590	COG3180	Ammonia monooxygenase
U14A_RS03595	COG2186	Transcriptional regulator
U14A_RS03600	COG0473	3-isopropylmalate dehydrogenase activity
U14A_RS03600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
U14A_RS03605	COG1063	alcohol dehydrogenase
U14A_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS03620	COG2721	sulfolactate sulfo-lyase activity
U14A_RS03625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
U14A_RS03635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
U14A_RS03640	COG0372	Belongs to the citrate synthase family
U14A_RS03650	COG2009	succinate dehydrogenase
U14A_RS03655	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
U14A_RS03660	COG1053	succinate dehydrogenase
U14A_RS03665	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
U14A_RS03670	COG0567	Dehydrogenase, E1 component
U14A_RS03675	COG0508	dehydrogenase complex catalyzes the overall conversion of
U14A_RS03685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
U14A_RS03690	COG2188	Transcriptional regulator
U14A_RS03695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS03695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS03695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS03700	COG0383	alpha-mannosidase activity
U14A_RS03715	COG1271	oxidase subunit
U14A_RS03720	COG1294	oxidase, subunit
U14A_RS03725	COG4890	Cyd operon protein YbgT
U14A_RS03730	COG3790	cyd operon protein YbgE
U14A_RS03735	COG0824	Thioesterase
U14A_RS03740	COG0811	peptide transport
U14A_RS03745	COG0848	biopolymer transport protein
U14A_RS03750	COG3064	Membrane
U14A_RS03760	COG2885	chlorophyll binding
U14A_RS03765	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
U14A_RS03805	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
U14A_RS03810	COG3201	nicotinamide mononucleotide transporter
U14A_RS03815	COG1230	cation diffusion facilitator family transporter
U14A_RS03825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
U14A_RS03835	COG2017	converts alpha-aldose to the beta-anomer
U14A_RS03845	COG1085	galactose-1-phosphate uridylyltransferase
U14A_RS03850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
U14A_RS03855	COG1119	ATPase activity
U14A_RS03860	COG3585	molybdate ion transport
U14A_RS03860	COG2005	Transcriptional regulator
U14A_RS03870	COG0725	ABC transporter, periplasmic molybdate-binding protein
U14A_RS03875	COG4149	molybdate abc transporter
U14A_RS03880	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
U14A_RS03885	COG0561	phosphatase activity
U14A_RS03895	COG0583	DNA-binding transcription factor activity
U14A_RS03900	COG2828	Protein conserved in bacteria
U14A_RS03905	COG0471	metal ion transport
U14A_RS03910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
U14A_RS03915	COG4677	pectinesterase activity
U14A_RS03920	COG1881	PFAM PEBP family protein
U14A_RS03925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
U14A_RS03940	COG2226	methyltransferase
U14A_RS03945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
U14A_RS03955	COG0391	Required for morphogenesis under gluconeogenic growth conditions
U14A_RS03965	COG0521	Mo-molybdopterin cofactor biosynthetic process
U14A_RS03975	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
U14A_RS03980	COG0314	molybdopterin synthase activity
U14A_RS03985	COG0670	Belongs to the BI1 family
U14A_RS03990	COG0670	Belongs to the BI1 family
U14A_RS03995	COG0392	lysyltransferase activity
U14A_RS04000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U14A_RS04005	COG3568	Endonuclease Exonuclease Phosphatase
U14A_RS04015	COG0842	Transport permease protein
U14A_RS04020	COG0842	Transport permease protein
U14A_RS04025	COG1131	(ABC) transporter
U14A_RS04035	COG1309	transcriptional regulator
U14A_RS04040	COG0513	Belongs to the DEAD box helicase family
U14A_RS04050	COG1199	ATP-dependent helicase activity
U14A_RS04055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
U14A_RS04060	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
U14A_RS04070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U14A_RS04075	COG3128	pkhd-type hydroxylase
U14A_RS04095	COG0668	transmembrane transport
U14A_RS04100	COG1126	abc transporter atp-binding protein
U14A_RS04105	COG0765	amino acid transport
U14A_RS04110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U14A_RS04120	COG5006	permease, DMT superfamily
U14A_RS04130	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
U14A_RS04135	COG2194	sulfuric ester hydrolase activity
U14A_RS04145	COG1321	iron dependent repressor
U14A_RS04150	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
U14A_RS04155	COG1376	ErfK ybiS ycfS ynhG family protein
U14A_RS04160	COG0488	(ABC) transporter
U14A_RS04165	COG0561	phosphatase activity
U14A_RS04170	COG1882	Formate acetyltransferase
U14A_RS04175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
U14A_RS04180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
U14A_RS04185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
U14A_RS04190	COG0303	'Molybdopterin
U14A_RS04195	COG1446	asparaginase
U14A_RS04220	COG2200	EAL domain
U14A_RS04225	COG2199	diguanylate cyclase activity
U14A_RS04240	COG2133	pyrroloquinoline quinone binding
U14A_RS04245	COG0625	glutathione transferase activity
U14A_RS04250	COG1686	Belongs to the peptidase S11 family
U14A_RS04255	COG1349	DNA-binding transcription factor activity
U14A_RS04260	COG0671	phosphoesterase, PA-phosphatase related
U14A_RS04265	COG2814	Major facilitator Superfamily
U14A_RS04275	COG0561	phosphatase activity
U14A_RS04280	COG0738	Major facilitator superfamily
U14A_RS04285	COG3226	Transcriptional regulator
U14A_RS04300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
U14A_RS04310	COG0778	Nitroreductase
U14A_RS04325	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
U14A_RS04330	COG3842	ATPase activity
U14A_RS04335	COG1176	ABC-type spermidine putrescine transport system, permease component I
U14A_RS04340	COG1177	transmembrane transport
U14A_RS04355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U14A_RS04360	COG4160	amino acid transport
U14A_RS04365	COG4215	(ABC) transporter
U14A_RS04370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U14A_RS04375	COG1126	abc transporter atp-binding protein
U14A_RS04390	COG3023	N-Acetylmuramoyl-L-alanine amidase
U14A_RS04395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U14A_RS04400	COG0702	epimerase
U14A_RS04405	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
U14A_RS04410	COG0028	Belongs to the TPP enzyme family
U14A_RS04415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
U14A_RS04420	COG1151	hydroxylamine reductase activity
U14A_RS04425	COG2431	L-lysine efflux transmembrane transporter activity
U14A_RS04430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
U14A_RS04435	COG3593	DNA synthesis involved in DNA repair
U14A_RS04440	COG2990	Protein conserved in bacteria
U14A_RS04445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U14A_RS04455	COG1278	Cold shock
U14A_RS04465	COG0542	response to heat
U14A_RS04485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
U14A_RS04490	COG4988	ABC transporter
U14A_RS04495	COG0492	ferredoxin-NADP+ reductase activity
U14A_RS04500	COG1522	sequence-specific DNA binding
U14A_RS04515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
U14A_RS04570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
U14A_RS04580	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
U14A_RS04670	COG4695	Portal protein
U14A_RS04695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
U14A_RS04790	COG4974	Belongs to the 'phage' integrase family
U14A_RS04795	COG0243	molybdopterin cofactor binding
U14A_RS04800	COG0437	4 iron, 4 sulfur cluster binding
U14A_RS04805	COG3302	dmso reductase anchor subunit
U14A_RS04810	COG1335	isochorismatase
U14A_RS04820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
U14A_RS04825	COG1882	Formate acetyltransferase
U14A_RS04830	COG2116	formate transmembrane transporter activity
U14A_RS04835	COG1944	ATP diphosphatase activity
U14A_RS04840	COG2323	membrane
U14A_RS04855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
U14A_RS04980	COG2369	cell adhesion
U14A_RS04990	COG4373	Mu-like prophage FluMu protein gp28
U14A_RS05075	COG3267	Type II secretory pathway component ExeA
U14A_RS05075	COG3409	Peptidoglycan-binding domain 1 protein
U14A_RS05085	COG4396	Host-nuclease inhibitor protein Gam
U14A_RS05125	COG4382	Mu-like prophage protein Gp16
U14A_RS05135	COG0501	Belongs to the peptidase M48B family
U14A_RS05145	COG0539	negative regulation of cytoplasmic translation
U14A_RS05155	COG0658	competence protein
U14A_RS05155	COG2333	competence protein COMEC
U14A_RS05170	COG3214	Protein conserved in bacteria
U14A_RS05185	COG3173	Aminoglycoside phosphotransferase
U14A_RS05190	COG1434	Gram-negative-bacterium-type cell wall biogenesis
U14A_RS05195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
U14A_RS05205	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
U14A_RS05215	COG2989	Protein conserved in bacteria
U14A_RS05220	COG3108	Peptidase M15
U14A_RS05225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U14A_RS05230	COG1448	Aminotransferase
U14A_RS05250	COG0308	aminopeptidase N
U14A_RS05255	COG1116	anion transmembrane transporter activity
U14A_RS05260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U14A_RS05270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U14A_RS05275	COG0431	NADPH-dependent FMN reductase
U14A_RS05295	COG0633	Ferredoxin
U14A_RS05295	COG3217	Mosc domain protein beta barrel domain protein
U14A_RS05305	COG0488	(ABC) transporter
U14A_RS05310	COG2995	paraquat-inducible protein a
U14A_RS05315	COG3008	intermembrane lipid transfer
U14A_RS05315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
U14A_RS05320	COG3009	Protein conserved in bacteria
U14A_RS05325	COG3130	regulation of translation
U14A_RS05335	COG1067	ATP-dependent peptidase activity
U14A_RS05355	COG3070	regulator of competence-specific genes
U14A_RS05360	COG1289	transmembrane transporter activity
U14A_RS05365	COG3304	Inner membrane component domain
U14A_RS05370	COG0210	DNA helicase
U14A_RS05385	COG1832	CoA-binding protein
U14A_RS05400	COG1254	Belongs to the acylphosphatase family
U14A_RS05405	COG2920	part of a sulfur-relay system
U14A_RS05410	COG0670	Belongs to the BI1 family
U14A_RS05420	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
U14A_RS05425	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
U14A_RS05430	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
U14A_RS05435	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
U14A_RS05440	COG1999	signal sequence binding
U14A_RS05445	COG1773	rubredoxin
U14A_RS05450	COG1271	oxidase subunit
U14A_RS05455	COG1294	oxidase, subunit
U14A_RS05470	COG1278	Cold shock
U14A_RS05475	COG1278	Cold shock
U14A_RS05495	COG0348	domain, Protein
U14A_RS05500	COG2198	Histidine kinase
U14A_RS05500	COG0784	Response regulator, receiver
U14A_RS05500	COG2205	protein histidine kinase activity
U14A_RS05505	COG1879	ABC-type sugar transport system periplasmic component
U14A_RS05510	COG0745	RESPONSE REGULATOR receiver
U14A_RS05515	COG3005	denitrification pathway
U14A_RS05520	COG0243	molybdopterin cofactor binding
U14A_RS05555	COG3729	General stress protein
U14A_RS05560	COG2233	PERMEase
U14A_RS05595	COG1309	transcriptional regulator
U14A_RS05600	COG0506	proline dehydrogenase activity
U14A_RS05600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
U14A_RS05600	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
U14A_RS05610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U14A_RS05630	COG1702	phosphate starvation-inducible protein PhoH
U14A_RS05635	COG3658	cytochrome
U14A_RS05640	COG1215	transferase activity, transferring glycosyl groups
U14A_RS05645	COG1649	PFAM Uncharacterised BCR, COG1649
U14A_RS05645	COG0726	polysaccharide deacetylase
U14A_RS05650	COG0457	Tetratricopeptide repeat
U14A_RS05655	COG3706	GGDEF domain
U14A_RS05675	COG3381	protein complex oligomerization
U14A_RS05685	COG1462	curli production assembly transport component CsgG
U14A_RS05700	COG2197	response regulator
U14A_RS05725	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
U14A_RS05730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U14A_RS05745	COG2943	transferase activity, transferring hexosyl groups
U14A_RS05750	COG5645	(Lipo)protein
U14A_RS05765	COG1560	Kdo2-lipid A biosynthetic process
U14A_RS05775	COG2353	YceI-like domain
U14A_RS05780	COG3038	cytochrome b561
U14A_RS05815	COG2999	glutathione oxidoreductase activity
U14A_RS05825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U14A_RS05835	COG0673	inositol 2-dehydrogenase activity
U14A_RS05840	COG0728	peptidoglycan biosynthetic process
U14A_RS05845	COG3418	PFAM FlgN family protein
U14A_RS05850	COG2747	anti-sigma28 factor FlgM
U14A_RS05855	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
U14A_RS05860	COG1815	bacterial-type flagellum-dependent cell motility
U14A_RS05865	COG1558	bacterial-type flagellum-dependent cell motility
U14A_RS05870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
U14A_RS05875	COG1749	Flagellar hook protein flgE
U14A_RS05880	COG4787	bacterial-type flagellum-dependent cell motility
U14A_RS05885	COG4786	Flagellar basal body rod
U14A_RS05915	COG1256	bacterial-type flagellum assembly
U14A_RS05920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
U14A_RS05925	COG1530	ribonuclease E activity
U14A_RS05935	COG0564	pseudouridine synthase activity
U14A_RS05940	COG0424	maF-like protein
U14A_RS05945	COG1399	metal-binding, possibly nucleic acid-binding protein
U14A_RS05965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
U14A_RS05970	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS05980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U14A_RS05985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
U14A_RS05990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
U14A_RS06000	COG0470	DNA polymerase III
U14A_RS06005	COG0084	hydrolase, TatD family'
U14A_RS06010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS06010	COG1263	PTS System
U14A_RS06015	COG4773	Receptor
U14A_RS06020	COG0537	adenosine 5'-monophosphoramidase activity
U14A_RS06025	COG5633	Lipoprotein
U14A_RS06030	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
U14A_RS06035	COG0510	thiamine kinase activity
U14A_RS06050	COG1252	NADH dehydrogenase
U14A_RS06055	COG3134	Outer membrane lipoprotein
U14A_RS06060	COG1309	transcriptional regulator
U14A_RS06070	COG1388	LysM domain
U14A_RS06070	COG1376	ErfK ybiS ycfS ynhG family protein
U14A_RS06075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
U14A_RS06080	COG4763	Acyl-transferase
U14A_RS06085	COG4591	ABC-type transport system involved in lipoprotein release permease component
U14A_RS06095	COG4591	ABC-type transport system involved in lipoprotein release permease component
U14A_RS06105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
U14A_RS06110	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
U14A_RS06120	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
U14A_RS06125	COG1177	transmembrane transport
U14A_RS06135	COG3842	ATPase activity
U14A_RS06145	COG2850	peptidyl-arginine hydroxylation
U14A_RS06150	COG2205	protein histidine kinase activity
U14A_RS06160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
U14A_RS06180	COG1187	pseudouridine synthase activity
U14A_RS06185	COG0538	isocitrate dehydrogenase activity
U14A_RS06190	COG0582	viral genome integration into host DNA
U14A_RS06280	COG1470	cell adhesion involved in biofilm formation
U14A_RS06280	COG1388	LysM domain
U14A_RS06360	COG4220	transposase activity
U14A_RS06380	COG1030	water channel activity
U14A_RS06430	COG1196	nuclear chromosome segregation
U14A_RS06460	COG5301	cellulose 1,4-beta-cellobiosidase activity
U14A_RS06475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
U14A_RS06480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
U14A_RS06485	COG1121	(ABC) transporter
U14A_RS06505	COG0538	isocitrate dehydrogenase activity
U14A_RS06515	COG5562	phage envelope protein
U14A_RS06520	COG0789	Transcriptional regulator
U14A_RS06525	COG2200	EAL domain
U14A_RS06605	COG2894	cell division
U14A_RS06630	COG0179	Fumarylacetoacetate (FAA) hydrolase
U14A_RS06645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
U14A_RS06650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
U14A_RS06660	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
U14A_RS06670	COG2719	SpoVR family
U14A_RS06680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
U14A_RS06690	COG1619	proteins homologs of microcin C7 resistance protein MccF
U14A_RS06700	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
U14A_RS06715	COG0157	Belongs to the NadC ModD family
U14A_RS06720	COG0500	methyltransferase
U14A_RS06725	COG1120	ATPase activity
U14A_RS06730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS06735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U14A_RS06750	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
U14A_RS06750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS06750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
U14A_RS06755	COG1461	Dihydroxyacetone kinase
U14A_RS06760	COG2376	Dihydroxyacetone kinase
U14A_RS06765	COG3284	Transcriptional regulator
U14A_RS06820	COG3423	Transcriptional regulator
U14A_RS06840	COG4372	Transposase
U14A_RS06845	COG3436	PFAM IS66 Orf2 family protein
U14A_RS06860	COG2003	Belongs to the UPF0758 family
U14A_RS06865	COG4974	Belongs to the 'phage' integrase family
U14A_RS06920	COG2801	Transposase and inactivated derivatives
U14A_RS06930	COG0582	viral genome integration into host DNA
U14A_RS06935	COG0012	GTP binding
U14A_RS06950	COG0659	secondary active sulfate transmembrane transporter activity
U14A_RS06955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
U14A_RS06980	COG2890	protein-(glutamine-N5) methyltransferase activity
U14A_RS06985	COG3094	Invasion gene expression up-regulator, SirB
U14A_RS06990	COG2912	Transglutaminase-like superfamily
U14A_RS07005	COG0387	Pfam Sodium calcium exchanger
U14A_RS07010	COG4572	Cation transport regulator
U14A_RS07015	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
U14A_RS07020	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
U14A_RS07025	COG4932	domain protein
U14A_RS07030	COG2197	response regulator
U14A_RS07035	COG3850	Histidine kinase
U14A_RS07040	COG2223	nitrite transmembrane transporter activity
U14A_RS07045	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
U14A_RS07050	COG1140	nitrate reductase beta subunit
U14A_RS07055	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
U14A_RS07060	COG2181	nitrate reductase activity
U14A_RS07065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
U14A_RS07070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U14A_RS07105	COG0788	formyltetrahydrofolate deformylase activity
U14A_RS07115	COG1752	Esterase of the alpha-beta hydrolase superfamily
U14A_RS07120	COG0745	RESPONSE REGULATOR receiver
U14A_RS07125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
U14A_RS07135	COG1435	thymidine kinase activity
U14A_RS07145	COG1454	alcohol dehydrogenase
U14A_RS07145	COG1012	belongs to the aldehyde dehydrogenase family
U14A_RS07150	COG2095	MarC family integral membrane protein
U14A_RS07155	COG4166	transmembrane transport
U14A_RS07160	COG0601	transmembrane transport
U14A_RS07165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U14A_RS07170	COG0444	Belongs to the ABC transporter superfamily
U14A_RS07175	COG4608	Belongs to the ABC transporter superfamily
U14A_RS07195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
U14A_RS07200	COG2350	Protein conserved in bacteria
U14A_RS07210	COG1607	acyl-coa hydrolase
U14A_RS07230	COG3047	cAMP biosynthetic process
U14A_RS07235	COG0582	viral genome integration into host DNA
U14A_RS07245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
U14A_RS07285	COG1846	Transcriptional regulator
U14A_RS07290	COG1484	DNA-dependent DNA replication
U14A_RS07295	COG1846	Transcriptional regulator
U14A_RS07305	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
U14A_RS07325	COG1403	HNH endonuclease
U14A_RS07330	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
U14A_RS07335	COG0484	heat shock protein binding
U14A_RS07395	COG3772	lysozyme
U14A_RS07530	COG4584	PFAM Integrase catalytic
U14A_RS07535	COG1484	DNA-dependent DNA replication
U14A_RS07545	COG5301	cellulose 1,4-beta-cellobiosidase activity
U14A_RS07560	COG5301	cellulose 1,4-beta-cellobiosidase activity
U14A_RS07570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
U14A_RS07585	COG0500	methyltransferase
U14A_RS07620	COG0135	phosphoribosylanthranilate isomerase activity
U14A_RS07620	COG0134	indole-3-glycerol-phosphate synthase activity
U14A_RS07625	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
U14A_RS07625	COG0512	Glutamine amidotransferase of anthranilate synthase
U14A_RS07630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
U14A_RS07640	COG0613	PHP domain protein
U14A_RS07645	COG0009	L-threonylcarbamoyladenylate synthase
U14A_RS07650	COG4907	membrane protein (DUF2207)
U14A_RS07655	COG1187	pseudouridine synthase activity
U14A_RS07670	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
U14A_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS07680	COG0616	signal peptide processing
U14A_RS07690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
U14A_RS07695	COG0583	DNA-binding transcription factor activity
U14A_RS07715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
U14A_RS07725	COG0671	phosphoesterase, PA-phosphatase related
U14A_RS07730	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
U14A_RS07735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
U14A_RS07745	COG0023	Translation Initiation Factor
U14A_RS07755	COG1349	DNA-binding transcription factor activity
U14A_RS07765	COG5001	Diguanylate cyclase
U14A_RS07780	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U14A_RS07780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U14A_RS07785	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
U14A_RS07795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U14A_RS07810	COG2814	Major facilitator Superfamily
U14A_RS07815	COG4172	Belongs to the ABC transporter superfamily
U14A_RS07820	COG4172	Belongs to the ABC transporter superfamily
U14A_RS07825	COG4171	peptide transport system, permease
U14A_RS07830	COG4168	peptide transport system, permease
U14A_RS07835	COG4166	transmembrane transport
U14A_RS07850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
U14A_RS07855	COG1842	Phage shock protein A
U14A_RS07865	COG1983	PspC domain protein
U14A_RS07875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U14A_RS07880	COG0366	Alpha amylase catalytic
U14A_RS07885	COG1653	transport
U14A_RS07890	COG1175	transmembrane transport
U14A_RS07895	COG0395	ABC-type sugar transport system, permease component
U14A_RS07900	COG1063	alcohol dehydrogenase
U14A_RS07905	COG1082	Xylose isomerase domain protein TIM barrel
U14A_RS07910	COG0673	inositol 2-dehydrogenase activity
U14A_RS07915	COG1554	hydrolase, family 65, central catalytic
U14A_RS07920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
U14A_RS07935	COG1609	Transcriptional regulator
U14A_RS07940	COG3106	COG3106 Predicted ATPase
U14A_RS07950	COG3283	Transcriptional regulator of aromatic amino acids metabolism
U14A_RS07955	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
U14A_RS07960	COG4948	Mandelate Racemase Muconate Lactonizing
U14A_RS07965	COG2866	Carboxypeptidase
U14A_RS07970	COG0702	epimerase
U14A_RS07980	COG1073	alpha beta
U14A_RS07985	COG0583	DNA-binding transcription factor activity
U14A_RS07990	COG4166	transmembrane transport
U14A_RS07995	COG0668	transmembrane transport
U14A_RS08000	COG3182	Iron-regulated membrane protein
U14A_RS08005	COG0589	response to stress
U14A_RS08010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U14A_RS08015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
U14A_RS08025	COG2207	Transcriptional regulator
U14A_RS08040	COG2840	Smr protein MutS2
U14A_RS08045	COG3706	GGDEF domain
U14A_RS08060	COG0513	Belongs to the DEAD box helicase family
U14A_RS08070	COG0582	viral genome integration into host DNA
U14A_RS08090	COG0589	response to stress
U14A_RS08095	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
U14A_RS08100	COG1013	pyruvate-flavodoxin oxidoreductase activity
U14A_RS08100	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
U14A_RS08100	COG0674	pyruvate-flavodoxin oxidoreductase activity
U14A_RS08100	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
U14A_RS08105	COG3042	response to heat
U14A_RS08110	COG3187	Heat shock protein
U14A_RS08115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
U14A_RS08120	COG2911	Protein conserved in bacteria
U14A_RS08130	COG3784	Protein of unknown function (DUF1318)
U14A_RS08140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
U14A_RS08150	COG0667	Aldo Keto reductase
U14A_RS08160	COG1643	Atp-dependent helicase
U14A_RS08165	COG1434	Gram-negative-bacterium-type cell wall biogenesis
U14A_RS08170	COG1012	belongs to the aldehyde dehydrogenase family
U14A_RS08175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
U14A_RS08180	COG3038	cytochrome b561
U14A_RS08200	COG0583	DNA-binding transcription factor activity
U14A_RS08205	COG5383	Protein conserved in bacteria
U14A_RS08215	COG2841	Protein conserved in bacteria
U14A_RS08220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U14A_RS08225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
U14A_RS08230	COG1275	C4-dicarboxylate transporter malic acid transport protein
U14A_RS08235	COG0500	methyltransferase
U14A_RS08245	COG3135	benzoate transporter
U14A_RS08250	COG1396	sequence-specific DNA binding
U14A_RS08255	COG0826	peptidase U32
U14A_RS08270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U14A_RS08275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
U14A_RS08280	COG3842	ATPase activity
U14A_RS08285	COG1176	ABC-type spermidine putrescine transport system, permease component I
U14A_RS08290	COG1177	transmembrane transport
U14A_RS08315	COG3238	Protein conserved in bacteria
U14A_RS08320	COG1247	-acetyltransferase
U14A_RS08330	COG1802	Transcriptional regulator
U14A_RS08335	COG4772	TonB-dependent receptor
U14A_RS08345	COG1113	amino acid transport
U14A_RS08355	COG5433	transposase activity
U14A_RS08360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
U14A_RS08365	COG2162	N-hydroxyarylamine O-acetyltransferase activity
U14A_RS08370	COG0384	phenazine biosynthesis protein PhzF
U14A_RS08375	COG2181	nitrate reductase activity
U14A_RS08380	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
U14A_RS08385	COG1140	nitrate reductase beta subunit
U14A_RS08390	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
U14A_RS08395	COG2223	nitrite transmembrane transporter activity
U14A_RS08400	COG0697	spore germination
U14A_RS08405	COG0243	molybdopterin cofactor binding
U14A_RS08405	COG3383	formate dehydrogenase (NAD+) activity
U14A_RS08410	COG3383	formate dehydrogenase (NAD+) activity
U14A_RS08410	COG0243	molybdopterin cofactor binding
U14A_RS08415	COG0437	4 iron, 4 sulfur cluster binding
U14A_RS08420	COG2864	formate dehydrogenase
U14A_RS08425	COG3093	addiction module antidote protein HigA
U14A_RS08435	COG1064	alcohol dehydrogenase
U14A_RS08455	COG1764	response to oxidative stress
U14A_RS08460	COG2202	Pas domain
U14A_RS08460	COG2199	diguanylate cyclase activity
U14A_RS08460	COG2200	EAL domain
U14A_RS08470	COG1649	PFAM Uncharacterised BCR, COG1649
U14A_RS08475	COG0531	amino acid
U14A_RS08480	COG0076	glutamate decarboxylase activity
U14A_RS08490	COG0612	Peptidase, M16
U14A_RS08495	COG0641	radical SAM
U14A_RS08500	COG3119	arylsulfatase activity
U14A_RS08505	COG2207	Transcriptional regulator
U14A_RS08515	COG0243	molybdopterin cofactor binding
U14A_RS08520	COG3539	Fimbrial protein
U14A_RS08525	COG3539	Fimbrial protein
U14A_RS08530	COG3539	Fimbrial protein
U14A_RS08535	COG3188	usher protein
U14A_RS08545	COG3539	Fimbrial protein
U14A_RS08560	COG3550	peptidyl-serine autophosphorylation
U14A_RS08565	COG1396	sequence-specific DNA binding
U14A_RS08575	COG3781	membrane
U14A_RS08585	COG2199	diguanylate cyclase activity
U14A_RS08595	COG2066	Belongs to the glutaminase family
U14A_RS08600	COG1012	belongs to the aldehyde dehydrogenase family
U14A_RS08605	COG0583	DNA-binding transcription factor activity
U14A_RS08625	COG1846	Transcriptional regulator
U14A_RS08630	COG4977	sequence-specific DNA binding
U14A_RS08640	COG0697	spore germination
U14A_RS08645	COG2814	Major facilitator Superfamily
U14A_RS08655	COG3706	GGDEF domain
U14A_RS08665	COG0339	signal peptide processing
U14A_RS08670	COG4221	oxidoreductase activity
U14A_RS08675	COG1802	Transcriptional regulator
U14A_RS08685	COG0246	Mannitol dehydrogenase
U14A_RS08690	COG0477	Major facilitator Superfamily
U14A_RS08695	COG1063	alcohol dehydrogenase
U14A_RS08700	COG4948	Mandelate Racemase Muconate Lactonizing
U14A_RS08715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U14A_RS08730	COG0243	molybdopterin cofactor binding
U14A_RS08745	COG0437	4 iron, 4 sulfur cluster binding
U14A_RS08750	COG3302	dmso reductase anchor subunit
U14A_RS08755	COG3381	protein complex oligomerization
U14A_RS08765	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
U14A_RS08770	COG1940	carbohydrate kinase activity
U14A_RS08775	COG0583	DNA-binding transcription factor activity
U14A_RS08780	COG2814	Major facilitator Superfamily
U14A_RS08795	COG3591	Belongs to the peptidase S1B family
U14A_RS08815	COG0628	permease
U14A_RS08820	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
U14A_RS08825	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
U14A_RS08835	COG0531	amino acid
U14A_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS08845	COG3136	membrane protein required for alginate biosynthesis
U14A_RS08850	COG0745	RESPONSE REGULATOR receiver
U14A_RS08855	COG2205	protein histidine kinase activity
U14A_RS08865	COG0114	fumarate hydratase activity
U14A_RS08870	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
U14A_RS08870	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
U14A_RS08875	COG1482	cell wall glycoprotein biosynthetic process
U14A_RS08880	COG5339	Protein conserved in bacteria
U14A_RS08895	COG3250	beta-galactosidase activity
U14A_RS08900	COG1309	transcriptional regulator
U14A_RS08905	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS08910	COG1609	Transcriptional regulator
U14A_RS08915	COG1263	PTS System
U14A_RS08915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS08920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
U14A_RS08930	COG0673	inositol 2-dehydrogenase activity
U14A_RS08970	COG4659	FMN binding
U14A_RS08980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
U14A_RS08985	COG3104	oligopeptide transport
U14A_RS08990	COG0625	glutathione transferase activity
U14A_RS09010	COG3895	Periplasmic Protein
U14A_RS09020	COG3133	Outer membrane lipoprotein
U14A_RS09035	COG1566	PFAM secretion protein HlyD family protein
U14A_RS09040	COG1289	transmembrane transporter activity
U14A_RS09045	COG2032	superoxide dismutase activity
U14A_RS09050	COG4989	oxidoreductase activity
U14A_RS09055	COG3313	Fe-S protein
U14A_RS09060	COG1309	transcriptional regulator
U14A_RS09065	COG1902	pentaerythritol trinitrate reductase activity
U14A_RS09070	COG0346	lactoylglutathione lyase activity
U14A_RS09080	COG1201	RNA secondary structure unwinding
U14A_RS09090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
U14A_RS09095	COG0791	NLP P60 protein
U14A_RS09100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
U14A_RS09105	COG2814	Major facilitator Superfamily
U14A_RS09120	COG0583	DNA-binding transcription factor activity
U14A_RS09125	COG2814	Major facilitator Superfamily
U14A_RS09130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
U14A_RS09135	COG0307	riboflavin synthase, alpha
U14A_RS09145	COG3468	outer membrane autotransporter barrel domain protein
U14A_RS09165	COG4529	Protein conserved in bacteria
U14A_RS09175	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
U14A_RS09180	COG0437	4 iron, 4 sulfur cluster binding
U14A_RS09190	COG2414	aldehyde ferredoxin oxidoreductase
U14A_RS09195	COG0437	4 iron, 4 sulfur cluster binding
U14A_RS09205	COG0469	pyruvate kinase activity
U14A_RS09210	COG4238	major outer membrane lipoprotein
U14A_RS09215	COG1376	ErfK ybiS ycfS ynhG family protein
U14A_RS09230	COG0719	Fe-S assembly protein
U14A_RS09235	COG0396	ATPase activity
U14A_RS09240	COG0719	Fe-S assembly protein
U14A_RS09245	COG0316	Belongs to the HesB IscA family
U14A_RS09255	COG2050	protein possibly involved in aromatic compounds catabolism
U14A_RS09260	COG0277	FAD linked oxidase domain protein
U14A_RS09260	COG0247	lactate metabolic process
U14A_RS09265	COG0628	permease
U14A_RS09280	COG0738	Major facilitator superfamily
U14A_RS09285	COG2271	Major facilitator Superfamily
U14A_RS09300	COG4670	ketone body catabolic process
U14A_RS09305	COG1960	acyl-CoA dehydrogenase activity
U14A_RS09310	COG2207	Transcriptional regulator
U14A_RS09310	COG1917	Cupin 2, conserved barrel domain protein
U14A_RS09315	COG2086	electron transfer activity
U14A_RS09320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
U14A_RS09325	COG0644	oxidoreductase
U14A_RS09330	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
U14A_RS09335	COG0318	PFAM AMP-dependent synthetase and ligase
U14A_RS09340	COG0574	Belongs to the PEP-utilizing enzyme family
U14A_RS09340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
U14A_RS09350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
U14A_RS09355	COG4256	Hemin uptake protein
U14A_RS09365	COG2200	EAL domain
U14A_RS09370	COG0791	NLP P60 protein
U14A_RS09380	COG0386	Belongs to the glutathione peroxidase family
U14A_RS09440	COG3137	Salt-induced outer membrane protein
U14A_RS09445	COG1105	Belongs to the carbohydrate kinase PfkB family
U14A_RS09455	COG3001	Fructosamine kinase
U14A_RS09465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
U14A_RS09470	COG1988	membrane-bound metal-dependent
U14A_RS09475	COG1823	symporter activity
U14A_RS09485	COG0753	catalase activity
U14A_RS09490	COG3394	polysaccharide catabolic process
U14A_RS09495	COG1486	melibiose metabolic process
U14A_RS09500	COG1917	Cupin 2, conserved barrel domain protein
U14A_RS09500	COG2169	Transcriptional regulator
U14A_RS09505	COG1447	Phosphotransferase system cellobiose-specific component IIA
U14A_RS09510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U14A_RS09515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U14A_RS09525	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
U14A_RS09535	COG0322	excinuclease ABC activity
U14A_RS09545	COG3678	ATP-independent chaperone mediated protein folding
U14A_RS09575	COG0708	Exodeoxyribonuclease III
U14A_RS09580	COG0398	Pfam SNARE associated Golgi protein
U14A_RS09590	COG0398	Pfam SNARE associated Golgi protein
U14A_RS09595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U14A_RS09600	COG4134	Bacterial extracellular solute-binding protein
U14A_RS09605	COG4135	transport system, permease component
U14A_RS09610	COG4136	ATPase activity
U14A_RS09615	COG2897	thiosulfate sulfurtransferase activity
U14A_RS09620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
U14A_RS09625	COG0494	nUDIX hydrolase
U14A_RS09635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
U14A_RS09640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
U14A_RS09645	COG0709	Synthesizes selenophosphate from selenide and ATP
U14A_RS09650	COG0778	Nitroreductase
U14A_RS09655	COG0616	signal peptide processing
U14A_RS09665	COG0252	asparaginase activity
U14A_RS09670	COG1335	isochorismatase
U14A_RS09675	COG2814	Major facilitator Superfamily
U14A_RS09680	COG1349	DNA-binding transcription factor activity
U14A_RS09685	COG0667	Aldo Keto reductase
U14A_RS09690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS09695	COG0191	fructose-bisphosphate aldolase activity
U14A_RS09700	COG1063	alcohol dehydrogenase
U14A_RS09705	COG2271	Major facilitator Superfamily
U14A_RS09710	COG1063	alcohol dehydrogenase
U14A_RS09715	COG3139	Protein of unknown function (DUF1315)
U14A_RS09725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
U14A_RS09730	COG0676	glucose-6-phosphate 1-epimerase activity
U14A_RS09735	COG0656	L-ascorbic acid biosynthetic process
U14A_RS09740	COG3713	MltA-interacting MipA family protein
U14A_RS09745	COG2766	serine protein kinase
U14A_RS09755	COG2199	diguanylate cyclase activity
U14A_RS09760	COG2199	diguanylate cyclase activity
U14A_RS09765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
U14A_RS09780	COG2207	Transcriptional regulator
U14A_RS09785	COG2807	transmembrane transport
U14A_RS09790	COG3189	MarR family transcriptional regulator
U14A_RS09795	COG3042	response to heat
U14A_RS09800	COG2203	Gaf domain
U14A_RS09800	COG2199	diguanylate cyclase activity
U14A_RS09815	COG2261	transglycosylase associated protein
U14A_RS09825	COG3615	Tellurite resistance protein tehB
U14A_RS09840	COG0473	3-isopropylmalate dehydrogenase activity
U14A_RS09845	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
U14A_RS09850	COG0318	PFAM AMP-dependent synthetase and ligase
U14A_RS09855	COG3065	identical protein binding
U14A_RS09860	COG1214	PFAM Peptidase M22, glycoprotease
U14A_RS09865	COG1199	ATP-dependent helicase activity
U14A_RS09870	COG0251	oxidation-reduction process
U14A_RS09885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
U14A_RS09895	COG1760	l-serine dehydratase
U14A_RS09900	COG2200	EAL domain
U14A_RS09905	COG1253	flavin adenine dinucleotide binding
U14A_RS09910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS09910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS09915	COG3715	PTS system
U14A_RS09920	COG3716	PTS system mannose fructose sorbose family IID component
U14A_RS09935	COG2226	methyltransferase
U14A_RS09965	COG1414	Transcriptional regulator
U14A_RS09970	COG2814	Major facilitator Superfamily
U14A_RS09980	COG0793	Belongs to the peptidase S41A family
U14A_RS09990	COG1956	GAF domain-containing protein
U14A_RS09995	COG2995	paraquat-inducible protein a
U14A_RS10000	COG3008	intermembrane lipid transfer
U14A_RS10020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
U14A_RS10030	COG1276	copper resistance
U14A_RS10035	COG2372	response to copper ion
U14A_RS10045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
U14A_RS10050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
U14A_RS10055	COG1770	oligopeptidase
U14A_RS10060	COG2979	Protein of unknown function (DUF533)
U14A_RS10070	COG3141	response to X-ray
U14A_RS10080	COG0800	Aldolase
U14A_RS10085	COG0129	dihydroxy-acid dehydratase activity
U14A_RS10090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
U14A_RS10095	COG1737	Transcriptional regulator
U14A_RS10100	COG0469	pyruvate kinase activity
U14A_RS10105	COG1560	Kdo2-lipid A biosynthetic process
U14A_RS10110	COG0739	heme binding
U14A_RS10115	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
U14A_RS10125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
U14A_RS10160	COG0217	transcriptional regulatory protein
U14A_RS10165	COG0494	nUDIX hydrolase
U14A_RS10175	COG1335	isochorismatase
U14A_RS10180	COG1801	Protein of unknown function DUF72
U14A_RS10185	COG3788	relative of glutathione S-transferase, MAPEG superfamily
U14A_RS10200	COG0243	molybdopterin cofactor binding
U14A_RS10205	COG3005	denitrification pathway
U14A_RS10215	COG3102	Protein conserved in bacteria
U14A_RS10230	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
U14A_RS10235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
U14A_RS10240	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
U14A_RS10245	COG0745	RESPONSE REGULATOR receiver
U14A_RS10255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
U14A_RS10265	COG0840	transmembrane signaling receptor activity
U14A_RS10270	COG0835	chemotaxis
U14A_RS10275	COG2198	Histidine kinase
U14A_RS10275	COG0643	Histidine kinase
U14A_RS10280	COG1360	Flagellar Motor Protein
U14A_RS10285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
U14A_RS10300	COG0589	response to stress
U14A_RS10310	COG1877	trehalose-phosphatase activity
U14A_RS10315	COG1172	Belongs to the binding-protein-dependent transport system permease family
U14A_RS10320	COG1129	ABC transporter
U14A_RS10325	COG1879	ABC-type sugar transport system periplasmic component
U14A_RS10330	COG1528	Iron-storage protein
U14A_RS10350	COG1528	Iron-storage protein
U14A_RS10360	COG0814	amino acid
U14A_RS10365	COG3318	Belongs to the UPF0149 family
U14A_RS10365	COG3012	SEC-C Motif Domain Protein
U14A_RS10470	COG0616	signal peptide processing
U14A_RS10600	COG0305	Participates in initiation and elongation during chromosome replication
U14A_RS10690	COG2197	response regulator
U14A_RS10705	COG2197	response regulator
U14A_RS10710	COG1126	abc transporter atp-binding protein
U14A_RS10715	COG0765	amino acid transport
U14A_RS10725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U14A_RS10735	COG1191	sigma factor activity
U14A_RS10740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
U14A_RS10745	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
U14A_RS10750	COG1516	flagellar protein fliS
U14A_RS10760	COG0366	Alpha amylase catalytic
U14A_RS10770	COG2391	methyltransferase activity
U14A_RS10775	COG0425	Belongs to the sulfur carrier protein TusA family
U14A_RS10780	COG2135	peptidase activity
U14A_RS10785	COG0675	Transposase, IS605 OrfB family
U14A_RS10795	COG2207	Transcriptional regulator
U14A_RS10800	COG1881	PFAM PEBP family protein
U14A_RS10805	COG2076	Multidrug Resistance protein
U14A_RS10820	COG1766	The M ring may be actively involved in energy transduction
U14A_RS10825	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U14A_RS10830	COG1317	bacterial-type flagellum organization
U14A_RS10835	COG1157	protein secretion by the type III secretion system
U14A_RS10840	COG2882	bacterial-type flagellum organization
U14A_RS10845	COG3144	bacterial-type flagellum assembly
U14A_RS10850	COG1580	Controls the rotational direction of flagella during chemotaxis
U14A_RS10855	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U14A_RS10860	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U14A_RS10865	COG3190	flagellar
U14A_RS10870	COG1338	Plays a role in the flagellum-specific transport system
U14A_RS10875	COG1987	bacterial-type flagellum assembly
U14A_RS10880	COG1684	flagellar biosynthetic protein fliR
U14A_RS10885	COG2197	response regulator
U14A_RS10915	COG5475	Uncharacterized small protein (DUF2158)
U14A_RS10920	COG2354	Protein conserved in bacteria
U14A_RS10925	COG0697	spore germination
U14A_RS10930	COG3727	T/G mismatch-specific endonuclease activity
U14A_RS10935	COG0270	DNA (cytosine-5-)-methyltransferase activity
U14A_RS10940	COG1418	mRNA catabolic process
U14A_RS10955	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
U14A_RS10970	COG2205	protein histidine kinase activity
U14A_RS10975	COG0745	RESPONSE REGULATOR receiver
U14A_RS10980	COG2351	hydroxyisourate hydrolase activity
U14A_RS11000	COG3443	Belongs to the bacterial solute-binding protein 9 family
U14A_RS11020	COG0582	viral genome integration into host DNA
U14A_RS11025	COG1169	isochorismate synthase
U14A_RS11030	COG2814	Major facilitator Superfamily
U14A_RS11035	COG1132	(ABC) transporter
U14A_RS11040	COG2375	cellular response to nickel ion
U14A_RS11040	COG1132	(ABC) transporter
U14A_RS11070	COG1021	2,3-dihydroxybenzoate-AMP ligase
U14A_RS11075	COG4771	TonB-dependent receptor
U14A_RS11080	COG4932	domain protein
U14A_RS11080	COG1388	LysM domain
U14A_RS11080	COG2373	Large extracellular alpha-helical protein
U14A_RS11085	COG1470	cell adhesion involved in biofilm formation
U14A_RS11085	COG1388	LysM domain
U14A_RS11090	COG1388	LysM domain
U14A_RS11090	COG1470	cell adhesion involved in biofilm formation
U14A_RS11095	COG1388	LysM domain
U14A_RS11095	COG1470	cell adhesion involved in biofilm formation
U14A_RS11105	COG0477	Major facilitator Superfamily
U14A_RS11110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
U14A_RS11115	COG0217	transcriptional regulatory protein
U14A_RS11125	COG0534	Mate efflux family protein
U14A_RS11135	COG0583	DNA-binding transcription factor activity
U14A_RS11140	COG0583	DNA-binding transcription factor activity
U14A_RS11150	COG1376	ErfK ybiS ycfS ynhG family protein
U14A_RS11165	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
U14A_RS11185	COG4771	TonB-dependent receptor
U14A_RS11195	COG3436	PFAM IS66 Orf2 family protein
U14A_RS11200	COG4372	Transposase
U14A_RS11205	COG1475	DNA binding
U14A_RS11210	COG3969	phosphoadenosine phosphosulfate
U14A_RS11215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
U14A_RS11220	COG1215	transferase activity, transferring glycosyl groups
U14A_RS11240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS11255	COG1735	metal-dependent hydrolase with the TIM-barrel fold
U14A_RS11305	COG3547	Transposase (IS116 IS110 IS902 family)
U14A_RS11370	COG1120	ATPase activity
U14A_RS11375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS11415	COG4584	PFAM Integrase catalytic
U14A_RS11420	COG1484	DNA-dependent DNA replication
U14A_RS11460	COG2003	Belongs to the UPF0758 family
U14A_RS11510	COG1289	transmembrane transporter activity
U14A_RS11520	COG1686	Belongs to the peptidase S11 family
U14A_RS11525	COG2925	Exonuclease
U14A_RS11550	COG0531	amino acid
U14A_RS11560	COG0583	DNA-binding transcription factor activity
U14A_RS11565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U14A_RS11570	COG4115	mRNA cleavage
U14A_RS11575	COG2161	toxin-antitoxin pair type II binding
U14A_RS11595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
U14A_RS11605	COG0131	Imidazoleglycerol-phosphate dehydratase
U14A_RS11605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
U14A_RS11610	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
U14A_RS11630	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
U14A_RS11635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
U14A_RS11640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
U14A_RS11650	COG0438	transferase activity, transferring glycosyl groups
U14A_RS11655	COG0110	maltose O-acetyltransferase activity
U14A_RS11665	COG0438	transferase activity, transferring glycosyl groups
U14A_RS11685	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
U14A_RS11690	COG1091	dTDP-4-dehydrorhamnose reductase activity
U14A_RS11695	COG1088	dTDP-glucose 4,6-dehydratase activity
U14A_RS11700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
U14A_RS11710	COG0438	transferase activity, transferring glycosyl groups
U14A_RS11715	COG2327	Polysaccharide pyruvyl transferase
U14A_RS11720	COG2244	polysaccharide biosynthetic process
U14A_RS11725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
U14A_RS11730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
U14A_RS11735	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
U14A_RS11735	COG0662	Cupin 2, conserved barrel domain protein
U14A_RS11740	COG0297	glycogen (starch) synthase activity
U14A_RS11745	COG1051	belongs to the nudix hydrolase family
U14A_RS11750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U14A_RS11755	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
U14A_RS11760	COG0110	maltose O-acetyltransferase activity
U14A_RS11765	COG1216	Glycosyl transferase, family 2
U14A_RS11775	COG0438	transferase activity, transferring glycosyl groups
U14A_RS11780	COG1045	serine acetyltransferase
U14A_RS11785	COG0463	Glycosyl transferase, family 2
U14A_RS11790	COG0489	protein tyrosine kinase activity
U14A_RS11790	COG3206	protein involved in exopolysaccharide biosynthesis
U14A_RS11795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
U14A_RS11800	COG1596	polysaccharide export
U14A_RS11805	COG1253	flavin adenine dinucleotide binding
U14A_RS11810	COG2982	Protein involved in outer membrane biogenesis
U14A_RS11820	COG0572	uridine kinase
U14A_RS11825	COG3447	MASE1 domain protein
U14A_RS11825	COG5001	Diguanylate cyclase
U14A_RS11825	COG5002	protein histidine kinase activity
U14A_RS11830	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
U14A_RS11835	COG0443	Heat shock 70 kDa protein
U14A_RS11840	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
U14A_RS11845	COG0631	protein serine/threonine phosphatase activity
U14A_RS11850	COG4245	von Willebrand factor, type A
U14A_RS11885	COG2205	protein histidine kinase activity
U14A_RS11890	COG0745	RESPONSE REGULATOR receiver
U14A_RS11900	COG0826	peptidase U32
U14A_RS11920	COG1063	alcohol dehydrogenase
U14A_RS11930	COG3414	Phosphotransferase system galactitol-specific IIB component
U14A_RS11935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS11950	COG1830	Aldolase
U14A_RS11955	COG2211	Major facilitator Superfamily
U14A_RS11960	COG1397	ADP-ribosylglycohydrolase
U14A_RS11965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS11970	COG2188	Transcriptional regulator
U14A_RS11975	COG3757	hydrolase, family 25
U14A_RS11980	COG0351	phosphomethylpyrimidine kinase
U14A_RS12000	COG5455	response to cobalt ion
U14A_RS12005	COG3539	Fimbrial protein
U14A_RS12010	COG3188	usher protein
U14A_RS12015	COG3121	Chaperone
U14A_RS12020	COG3539	Fimbrial protein
U14A_RS12030	COG0489	protein tyrosine kinase activity
U14A_RS12040	COG3831	ATPase activity
U14A_RS12045	COG3831	ATPase activity
U14A_RS12050	COG3831	ATPase activity
U14A_RS12060	COG0714	Associated with various cellular activities
U14A_RS12065	COG2425	protein containing a von Willebrand factor type A (vWA) domain
U14A_RS12070	COG3552	Protein containing von Willebrand factor type A (VWA) domain
U14A_RS12075	COG4715	Zinc finger, swim domain protein
U14A_RS12080	COG4808	Protein conserved in bacteria
U14A_RS12085	COG4807	Protein conserved in bacteria
U14A_RS12090	COG3279	Response regulator of the LytR AlgR family
U14A_RS12095	COG3275	phosphorelay sensor kinase activity
U14A_RS12100	COG0789	Transcriptional regulator
U14A_RS12110	COG1174	glycine betaine transport
U14A_RS12115	COG1125	glycine betaine transport
U14A_RS12120	COG1174	glycine betaine transport
U14A_RS12125	COG1732	Glycine betaine
U14A_RS12130	COG1472	Belongs to the glycosyl hydrolase 3 family
U14A_RS12135	COG0277	FAD linked oxidase domain protein
U14A_RS12140	COG1686	Belongs to the peptidase S11 family
U14A_RS12150	COG0586	Pfam SNARE associated Golgi protein
U14A_RS12155	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS12170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
U14A_RS12180	COG1346	cytolysis
U14A_RS12190	COG2949	membrane
U14A_RS12200	COG0493	'glutamate synthase
U14A_RS12205	COG0167	dihydroorotate dehydrogenase activity
U14A_RS12205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
U14A_RS12210	COG4211	Belongs to the binding-protein-dependent transport system permease family
U14A_RS12220	COG1879	ABC-type sugar transport system periplasmic component
U14A_RS12225	COG1609	Transcriptional regulator
U14A_RS12230	COG2311	Membrane
U14A_RS12245	COG4771	TonB-dependent receptor
U14A_RS12255	COG0833	amino acid
U14A_RS12260	COG0583	DNA-binding transcription factor activity
U14A_RS12265	COG2855	membrane
U14A_RS12275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS12275	COG1522	sequence-specific DNA binding
U14A_RS12285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U14A_RS12290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
U14A_RS12295	COG2313	pseudouridylate synthase activity
U14A_RS12300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS12305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS12305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
U14A_RS12305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS12310	COG1105	Belongs to the carbohydrate kinase PfkB family
U14A_RS12315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS12315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS12320	COG2814	Major facilitator Superfamily
U14A_RS12335	COG0246	Mannitol dehydrogenase
U14A_RS12340	COG0523	cobalamin synthesis protein
U14A_RS12345	COG0671	phosphoesterase, PA-phosphatase related
U14A_RS12350	COG0791	NLP P60 protein
U14A_RS12355	COG2200	EAL domain
U14A_RS12360	COG4166	transmembrane transport
U14A_RS12365	COG4174	ABC transporter (Permease)
U14A_RS12370	COG4239	(ABC) transporter, permease
U14A_RS12375	COG4172	Belongs to the ABC transporter superfamily
U14A_RS12385	COG2814	Major facilitator Superfamily
U14A_RS12390	COG1187	pseudouridine synthase activity
U14A_RS12395	COG1061	Type III restriction enzyme res subunit
U14A_RS12415	COG3083	sulfuric ester hydrolase activity
U14A_RS12430	COG2197	response regulator
U14A_RS12435	COG3088	subunit of a heme lyase
U14A_RS12435	COG4235	cytochrome complex assembly
U14A_RS12440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U14A_RS12445	COG1138	Cytochrome C-type biogenesis protein
U14A_RS12455	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
U14A_RS12460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
U14A_RS12465	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
U14A_RS12470	COG4133	protoheme IX ABC transporter activity
U14A_RS12475	COG3005	denitrification pathway
U14A_RS12480	COG3043	anaerobic respiration
U14A_RS12485	COG0348	domain, Protein
U14A_RS12490	COG0437	4 iron, 4 sulfur cluster binding
U14A_RS12500	COG3062	negative regulation of establishment of protein localization
U14A_RS12505	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS12505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS12520	COG4615	Cyclic peptide transporter
U14A_RS12525	COG3145	DNA-N1-methyladenine dioxygenase activity
U14A_RS12530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
U14A_RS12530	COG2169	Transcriptional regulator
U14A_RS12535	COG1477	protein flavinylation
U14A_RS12545	COG0642	Histidine kinase
U14A_RS12545	COG2198	Histidine kinase
U14A_RS12550	COG2197	response regulator
U14A_RS12555	COG0784	Response regulator, receiver
U14A_RS12555	COG2205	protein histidine kinase activity
U14A_RS12560	COG3852	Histidine kinase
U14A_RS12565	COG2204	response regulator
U14A_RS12570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
U14A_RS12575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
U14A_RS12580	COG2031	fatty acid transporter
U14A_RS12585	COG0183	Belongs to the thiolase family
U14A_RS12590	COG4676	Protein conserved in bacteria
U14A_RS12595	COG5445	Predicted secreted protein (DUF2300)
U14A_RS12600	COG2373	Large extracellular alpha-helical protein
U14A_RS12605	COG3234	Protein of unknown function (DUF1175)
U14A_RS12610	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
U14A_RS12615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
U14A_RS12625	COG3468	outer membrane autotransporter barrel domain protein
U14A_RS12630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U14A_RS12635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U14A_RS12640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
U14A_RS12645	COG3642	lipopolysaccharide core region biosynthetic process
U14A_RS12650	COG0584	glycerophosphoryl diester phosphodiesterase
U14A_RS12655	COG2271	Major facilitator Superfamily
U14A_RS12660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
U14A_RS12670	COG0247	lactate metabolic process
U14A_RS12675	COG5464	transposase or invertase
U14A_RS12685	COG3836	Belongs to the HpcH HpaI aldolase family
U14A_RS12690	COG2271	Major facilitator Superfamily
U14A_RS12695	COG4948	Mandelate Racemase Muconate Lactonizing
U14A_RS12700	COG1414	Transcriptional regulator
U14A_RS12745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
U14A_RS12765	COG0318	PFAM AMP-dependent synthetase and ligase
U14A_RS12775	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
U14A_RS12790	COG1169	isochorismate synthase
U14A_RS12795	COG4575	ribosome binding
U14A_RS12800	COG2153	protein acetylation
U14A_RS12810	COG2304	oxidoreductase activity
U14A_RS12815	COG2234	aminopeptidase activity
U14A_RS12830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
U14A_RS12835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
U14A_RS12845	COG0839	Belongs to the complex I subunit 6 family
U14A_RS12860	COG1034	ATP synthesis coupled electron transport
U14A_RS12865	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
U14A_RS12870	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
U14A_RS12890	COG0583	DNA-binding transcription factor activity
U14A_RS12895	COG0436	Aminotransferase
U14A_RS12905	COG0490	domain, Protein
U14A_RS12905	COG0471	metal ion transport
U14A_RS12910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
U14A_RS12925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
U14A_RS12930	COG0280	phosphate acetyltransferase
U14A_RS12930	COG0857	belongs to the CobB CobQ family
U14A_RS12935	COG1288	antiporter activity
U14A_RS12940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
U14A_RS12945	COG0622	Phosphoesterase
U14A_RS12950	COG0625	glutathione transferase activity
U14A_RS12955	COG0625	glutathione transferase activity
U14A_RS12960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
U14A_RS12965	COG1090	epimerase
U14A_RS12970	COG4598	ABC transporter
U14A_RS12975	COG4160	amino acid transport
U14A_RS12980	COG4215	(ABC) transporter
U14A_RS12985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U14A_RS12990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U14A_RS12995	COG0163	prenyltransferase activity
U14A_RS13000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
U14A_RS13005	COG1286	toxin biosynthetic process
U14A_RS13010	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
U14A_RS13015	COG0285	dihydrofolate synthase activity
U14A_RS13025	COG0586	Pfam SNARE associated Golgi protein
U14A_RS13035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
U14A_RS13050	COG2814	Major facilitator Superfamily
U14A_RS13055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U14A_RS13070	COG3101	peptidyl-lysine hydroxylation
U14A_RS13075	COG0730	response to heat
U14A_RS13105	COG3539	Fimbrial protein
U14A_RS13110	COG3539	Fimbrial protein
U14A_RS13115	COG3539	Fimbrial protein
U14A_RS13120	COG3121	Chaperone
U14A_RS13125	COG3188	usher protein
U14A_RS13130	COG3539	Fimbrial protein
U14A_RS13135	COG2062	phosphohistidine phosphatase, SixA
U14A_RS13150	COG3691	Protein conserved in bacteria
U14A_RS13165	COG2116	formate transmembrane transporter activity
U14A_RS13175	COG0582	viral genome integration into host DNA
U14A_RS13235	COG0583	DNA-binding transcription factor activity
U14A_RS13240	COG2610	gluconate transmembrane transporter activity
U14A_RS13250	COG0477	Major facilitator Superfamily
U14A_RS13255	COG1566	PFAM secretion protein HlyD family protein
U14A_RS13260	COG2197	response regulator
U14A_RS13265	COG2198	Histidine kinase
U14A_RS13265	COG0784	Response regulator, receiver
U14A_RS13265	COG2205	protein histidine kinase activity
U14A_RS13265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U14A_RS13270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
U14A_RS13275	COG0679	Auxin Efflux Carrier
U14A_RS13280	COG0028	Belongs to the TPP enzyme family
U14A_RS13305	COG1560	Kdo2-lipid A biosynthetic process
U14A_RS13315	COG0436	Aminotransferase
U14A_RS13320	COG3275	phosphorelay sensor kinase activity
U14A_RS13325	COG3279	Response regulator of the LytR AlgR family
U14A_RS13330	COG2207	Transcriptional regulator
U14A_RS13335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS13335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS13335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
U14A_RS13340	COG1363	Peptidase, m42
U14A_RS13345	COG0006	proline dipeptidase activity
U14A_RS13350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS13355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS13380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
U14A_RS13385	COG2199	diguanylate cyclase activity
U14A_RS13385	COG2200	EAL domain
U14A_RS13400	COG3415	Transposase
U14A_RS13405	COG3415	Transposase
U14A_RS13410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
U14A_RS13435	COG0583	DNA-binding transcription factor activity
U14A_RS13445	COG2211	Major facilitator Superfamily
U14A_RS13450	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
U14A_RS13460	COG0583	DNA-binding transcription factor activity
U14A_RS13465	COG0385	Bile acid
U14A_RS13470	COG3530	Putative quorum-sensing-regulated virulence factor
U14A_RS13490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
U14A_RS13495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS13500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
U14A_RS13505	COG2190	(PTS) system
U14A_RS13520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
U14A_RS13525	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
U14A_RS13530	COG4208	sulfate ABC transporter
U14A_RS13535	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
U14A_RS13540	COG4150	thiosulfate binding
U14A_RS13545	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS13560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS13560	COG1263	PTS System
U14A_RS13565	COG2837	iron assimilation
U14A_RS13585	COG0860	N-Acetylmuramoyl-L-alanine amidase
U14A_RS13595	COG2207	Transcriptional regulator
U14A_RS13600	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
U14A_RS13605	COG4816	utilization protein
U14A_RS13615	COG4303	Ethanolamine ammonia lyase large subunit
U14A_RS13620	COG4819	ethanolamine utilization protein
U14A_RS13625	COG3192	ethanolamine utilization protein
U14A_RS13630	COG1454	alcohol dehydrogenase
U14A_RS13635	COG4820	ethanolamine utilization protein (EutJ)
U14A_RS13640	COG1012	belongs to the aldehyde dehydrogenase family
U14A_RS13645	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
U14A_RS13650	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
U14A_RS13655	COG0280	phosphate acetyltransferase
U14A_RS13660	COG4812	Cobalamin adenosyltransferase
U14A_RS13665	COG4766	ethanolamine catabolic process
U14A_RS13670	COG4917	ethanolamine utilization protein
U14A_RS13685	COG0281	malic enzyme
U14A_RS13685	COG0280	phosphate acetyltransferase
U14A_RS13690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
U14A_RS13695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
U14A_RS13700	COG5342	invasion associated locus B
U14A_RS13710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS13710	COG0493	'glutamate synthase
U14A_RS13715	COG3850	Histidine kinase
U14A_RS13720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U14A_RS13730	COG1393	Belongs to the ArsC family
U14A_RS13745	COG0400	carboxylic ester hydrolase activity
U14A_RS13755	COG2321	neutral zinc metallopeptidase
U14A_RS13765	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
U14A_RS13775	COG2716	regulation of RNA biosynthetic process
U14A_RS13780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
U14A_RS13785	COG0628	permease
U14A_RS13790	COG4783	chaperone-mediated protein folding
U14A_RS13795	COG1393	Belongs to the ArsC family
U14A_RS13805	COG2233	PERMEase
U14A_RS13820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
U14A_RS13825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
U14A_RS13830	COG0248	Ppx GppA phosphatase
U14A_RS13835	COG2200	EAL domain
U14A_RS13845	COG3133	Outer membrane lipoprotein
U14A_RS13860	COG0516	GMP reductase activity
U14A_RS13860	COG0517	IMP dehydrogenase activity
U14A_RS13885	COG1645	bacterial-type flagellum-dependent swarming motility
U14A_RS13900	COG2976	Protein conserved in bacteria
U14A_RS13930	COG4953	penicillin-binding protein 1C
U14A_RS13935	COG2373	Large extracellular alpha-helical protein
U14A_RS13940	COG2897	thiosulfate sulfurtransferase activity
U14A_RS13955	COG2975	iron-sulfur cluster assembly
U14A_RS13960	COG0633	Ferredoxin
U14A_RS13980	COG0822	iron-sulfur transferase activity
U14A_RS14000	COG0483	inositol monophosphate 1-phosphatase activity
U14A_RS14005	COG1073	alpha beta
U14A_RS14010	COG3711	transcriptional antiterminator
U14A_RS14015	COG2814	Major facilitator Superfamily
U14A_RS14020	COG2259	Doxx family
U14A_RS14025	COG2017	converts alpha-aldose to the beta-anomer
U14A_RS14030	COG1063	alcohol dehydrogenase
U14A_RS14035	COG1172	Belongs to the binding-protein-dependent transport system permease family
U14A_RS14040	COG1129	ABC transporter
U14A_RS14045	COG1879	ABC-type sugar transport system periplasmic component
U14A_RS14050	COG0457	Tetratricopeptide repeat
U14A_RS14055	COG1940	carbohydrate kinase activity
U14A_RS14065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
U14A_RS14065	COG1017	nitric oxide dioxygenase activity
U14A_RS14070	COG0347	Belongs to the P(II) protein family
U14A_RS14075	COG2204	response regulator
U14A_RS14080	COG3170	Tfp pilus assembly protein FimV
U14A_RS14085	COG2205	protein histidine kinase activity
U14A_RS14100	COG0590	tRNA wobble adenosine to inosine editing
U14A_RS14105	COG0560	Phosphoserine phosphatase
U14A_RS14110	COG1737	Transcriptional regulator
U14A_RS14115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS14130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
U14A_RS14150	COG0681	Belongs to the peptidase S26 family
U14A_RS14160	COG3086	response to oxidative stress
U14A_RS14165	COG3026	antisigma factor binding
U14A_RS14170	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
U14A_RS14175	COG1595	DNA-templated transcription, initiation
U14A_RS14185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
U14A_RS14195	COG0513	Belongs to the DEAD box helicase family
U14A_RS14200	COG0583	DNA-binding transcription factor activity
U14A_RS14220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
U14A_RS14225	COG3118	belongs to the thioredoxin family
U14A_RS14230	COG3148	PFAM DTW domain containing protein
U14A_RS14235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U14A_RS14235	COG0045	succinate-CoA ligase (ADP-forming) activity
U14A_RS14235	COG1042	CoA-binding domain protein
U14A_RS14240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U14A_RS14245	COG5544	Lipoprotein
U14A_RS14250	COG0477	Major facilitator Superfamily
U14A_RS14275	COG0542	response to heat
U14A_RS14285	COG0564	pseudouridine synthase activity
U14A_RS14290	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
U14A_RS14295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
U14A_RS14305	COG0077	Prephenate dehydratase
U14A_RS14305	COG1605	Chorismate mutase
U14A_RS14310	COG0287	Prephenate dehydrogenase
U14A_RS14310	COG1605	Chorismate mutase
U14A_RS14315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
U14A_RS14330	COG2199	diguanylate cyclase activity
U14A_RS14335	COG2885	chlorophyll binding
U14A_RS14360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
U14A_RS14365	COG4137	Cytochrome C assembly protein
U14A_RS14370	COG4536	flavin adenine dinucleotide binding
U14A_RS14390	COG0497	DNA recombination
U14A_RS14395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
U14A_RS14405	COG2867	negative regulation of translational initiation
U14A_RS14430	COG0579	oxidoreductase
U14A_RS14435	COG1012	belongs to the aldehyde dehydrogenase family
U14A_RS14440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
U14A_RS14445	COG1113	amino acid transport
U14A_RS14450	COG1802	Transcriptional regulator
U14A_RS14455	COG1652	LysM domain
U14A_RS14460	COG0401	homolog of Blt101
U14A_RS14465	COG0640	Transcriptional regulator
U14A_RS14470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U14A_RS14475	COG2916	Histone family protein nucleoid-structuring protein H-NS
U14A_RS14490	COG4575	ribosome binding
U14A_RS14495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
U14A_RS14505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U14A_RS14510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U14A_RS14520	COG4175	Glycine betaine
U14A_RS14525	COG4176	ABC-type proline glycine betaine transport system permease component
U14A_RS14530	COG2113	Glycine betaine
U14A_RS14535	COG2814	Major facilitator Superfamily
U14A_RS14540	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
U14A_RS14550	COG1846	Transcriptional regulator
U14A_RS14555	COG1566	PFAM secretion protein HlyD family protein
U14A_RS14560	COG2814	Major facilitator Superfamily
U14A_RS14585	COG1238	metal cluster binding
U14A_RS14590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
U14A_RS14620	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
U14A_RS14640	COG1546	Belongs to the CinA family
U14A_RS14650	COG2951	lytic endotransglycosylase activity
U14A_RS14655	COG3730	PTS system glucitol sorbitol-specific
U14A_RS14660	COG3732	PTS system glucitol sorbitol-specific
U14A_RS14670	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS14675	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS14680	COG1349	DNA-binding transcription factor activity
U14A_RS14685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
U14A_RS14685	COG0517	IMP dehydrogenase activity
U14A_RS14705	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
U14A_RS14710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS14725	COG5499	transcription regulator containing HTH domain
U14A_RS14735	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
U14A_RS14745	COG3260	NADH ubiquinone oxidoreductase 20
U14A_RS14750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
U14A_RS14755	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
U14A_RS14755	COG3261	NADH dehydrogenase
U14A_RS14760	COG0650	Formate hydrogenlyase subunit 4
U14A_RS14765	COG0651	ATP synthesis coupled electron transport
U14A_RS14770	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS14785	COG0375	protein maturation
U14A_RS14790	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
U14A_RS14795	COG0298	carbon dioxide binding
U14A_RS14800	COG0409	Hydrogenase expression formation protein
U14A_RS14805	COG0309	Hydrogenase expression formation protein (HypE)
U14A_RS14825	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
U14A_RS14830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
U14A_RS14835	COG1349	DNA-binding transcription factor activity
U14A_RS14840	COG2084	Dehydrogenase
U14A_RS14845	COG3395	kinase activity
U14A_RS14850	COG0235	Class ii aldolase
U14A_RS14855	COG3622	Belongs to the hyi family
U14A_RS14860	COG2610	gluconate transmembrane transporter activity
U14A_RS14875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
U14A_RS14880	COG1388	LysM domain
U14A_RS14880	COG4942	peptidase
U14A_RS14895	COG0585	pseudouridine synthase activity
U14A_RS14935	COG2234	aminopeptidase activity
U14A_RS14965	COG0720	synthase
U14A_RS14970	COG0644	oxidoreductase
U14A_RS14975	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
U14A_RS14980	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
U14A_RS14985	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
U14A_RS14990	COG2086	electron transfer activity
U14A_RS14995	COG0477	Major facilitator Superfamily
U14A_RS15000	COG0277	FAD linked oxidase domain protein
U14A_RS15005	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS15010	COG2223	nitrite transmembrane transporter activity
U14A_RS15015	COG1070	Carbohydrate kinase
U14A_RS15045	COG0602	queuosine metabolic process
U14A_RS15055	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
U14A_RS15070	COG3956	TIGRFAM MazG family protein
U14A_RS15075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
U14A_RS15085	COG3850	Histidine kinase
U14A_RS15085	COG3437	response regulator, receiver
U14A_RS15085	COG2205	protein histidine kinase activity
U14A_RS15085	COG4999	Histidine kinase
U14A_RS15090	COG4948	Mandelate Racemase Muconate Lactonizing
U14A_RS15095	COG4948	Mandelate Racemase Muconate Lactonizing
U14A_RS15100	COG2271	Major facilitator Superfamily
U14A_RS15105	COG0716	FMN binding
U14A_RS15110	COG0564	pseudouridine synthase activity
U14A_RS15115	COG3098	single-species biofilm formation
U14A_RS15130	COG1611	Belongs to the LOG family
U14A_RS15135	COG0814	amino acid
U14A_RS15140	COG1760	l-serine dehydratase
U14A_RS15150	COG1454	alcohol dehydrogenase
U14A_RS15155	COG0235	Class ii aldolase
U14A_RS15160	COG0738	Major facilitator superfamily
U14A_RS15170	COG1070	Carbohydrate kinase
U14A_RS15180	COG1349	DNA-binding transcription factor activity
U14A_RS15190	COG2363	Small membrane protein
U14A_RS15195	COG0583	DNA-binding transcription factor activity
U14A_RS15205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
U14A_RS15210	COG2166	iron-sulfur cluster assembly
U14A_RS15215	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
U14A_RS15220	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
U14A_RS15260	COG2885	chlorophyll binding
U14A_RS15335	COG4584	PFAM Integrase catalytic
U14A_RS15340	COG1484	DNA-dependent DNA replication
U14A_RS15405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
U14A_RS15410	COG1263	PTS System
U14A_RS15410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS15415	COG3711	transcriptional antiterminator
U14A_RS15420	COG0860	N-Acetylmuramoyl-L-alanine amidase
U14A_RS15425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
U14A_RS15425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
U14A_RS15430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
U14A_RS15435	COG1074	ATP-dependent DNA helicase activity
U14A_RS15440	COG1025	Belongs to the peptidase M16 family
U14A_RS15445	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
U14A_RS15450	COG4967	type IV pilus modification protein PilV
U14A_RS15460	COG4795	General secretion pathway protein
U14A_RS15465	COG2165	general secretion pathway protein
U14A_RS15480	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
U14A_RS15500	COG0861	Integral membrane protein TerC family
U14A_RS15510	COG0667	Aldo Keto reductase
U14A_RS15525	COG1609	Transcriptional regulator
U14A_RS15535	COG0583	DNA-binding transcription factor activity
U14A_RS15540	COG1794	racemase activity, acting on amino acids and derivatives
U14A_RS15545	COG2814	Major facilitator Superfamily
U14A_RS15550	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS15560	COG0183	Belongs to the thiolase family
U14A_RS15565	COG0814	amino acid
U14A_RS15575	COG4942	peptidase
U14A_RS15580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
U14A_RS15585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
U14A_RS15590	COG2080	2 iron, 2 sulfur cluster binding
U14A_RS15595	COG3829	transcription factor binding
U14A_RS15600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
U14A_RS15605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
U14A_RS15625	COG0549	Belongs to the carbamate kinase family
U14A_RS15630	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
U14A_RS15630	COG3608	succinylglutamate desuccinylase aspartoacylase
U14A_RS15635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
U14A_RS15640	COG2068	MobA-Related Protein
U14A_RS15645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS15645	COG0493	'glutamate synthase
U14A_RS15650	COG0402	S-adenosylhomocysteine deaminase activity
U14A_RS15655	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
U14A_RS15660	COG2080	2 iron, 2 sulfur cluster binding
U14A_RS15660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
U14A_RS15665	COG2233	PERMEase
U14A_RS15670	COG0402	S-adenosylhomocysteine deaminase activity
U14A_RS15675	COG2252	PERMEase
U14A_RS15680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS15685	COG0493	'glutamate synthase
U14A_RS15685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS15690	COG2233	PERMEase
U14A_RS15710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
U14A_RS15720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
U14A_RS15725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
U14A_RS15730	COG4974	Belongs to the 'phage' integrase family
U14A_RS15735	COG0716	FMN binding
U14A_RS15745	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
U14A_RS15755	COG1272	protein, Hemolysin III
U14A_RS15765	COG2723	6-phospho-beta-galactosidase activity
U14A_RS15790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
U14A_RS15795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
U14A_RS15800	COG0006	proline dipeptidase activity
U14A_RS15820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
U14A_RS15830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
U14A_RS15850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
U14A_RS15850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
U14A_RS15855	COG0583	DNA-binding transcription factor activity
U14A_RS15865	COG2968	Membrane
U14A_RS15870	COG1279	arginine transmembrane transporter activity
U14A_RS15875	COG0668	transmembrane transport
U14A_RS15880	COG0191	fructose-bisphosphate aldolase activity
U14A_RS15915	COG1122	ATPase activity
U14A_RS15920	COG1072	(Pantothenic acid kinase))
U14A_RS15930	COG1494	fructose-1,6-bisphosphatase
U14A_RS15935	COG1063	alcohol dehydrogenase
U14A_RS15940	COG2213	PTS system mannitol-specific
U14A_RS15945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS15955	COG0330	HflC and HflK could
U14A_RS15960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
U14A_RS15965	COG0501	Belongs to the peptidase M48B family
U14A_RS15980	COG1166	arginine decarboxylase activity
U14A_RS16005	COG2814	Major facilitator Superfamily
U14A_RS16015	COG2356	endonuclease I
U14A_RS16020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
U14A_RS16025	COG0189	ligase activity
U14A_RS16040	COG2805	Type II/IV secretion system protein
U14A_RS16045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
U14A_RS16050	COG0762	integral membrane protein
U14A_RS16060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
U14A_RS16065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
U14A_RS16070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
U14A_RS16075	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
U14A_RS16090	COG0252	asparaginase activity
U14A_RS16100	COG3171	Protein conserved in bacteria
U14A_RS16110	COG1194	a g-specific adenine glycosylase
U14A_RS16125	COG2211	Major facilitator Superfamily
U14A_RS16130	COG1982	Orn Lys Arg decarboxylase major
U14A_RS16135	COG1811	Na channel or pump
U14A_RS16145	COG0582	viral genome integration into host DNA
U14A_RS16280	COG3468	outer membrane autotransporter barrel domain protein
U14A_RS16290	COG2826	transposase and inactivated derivatives, IS30 family
U14A_RS16310	COG3436	PFAM IS66 Orf2 family protein
U14A_RS16370	COG4771	TonB-dependent receptor
U14A_RS16400	COG2755	lipolytic protein G-D-S-L family
U14A_RS16400	COG0657	acetylesterase activity
U14A_RS16405	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
U14A_RS16410	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
U14A_RS16420	COG2814	Major facilitator Superfamily
U14A_RS16425	COG1940	carbohydrate kinase activity
U14A_RS16430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U14A_RS16435	COG3385	transposase activity
U14A_RS16450	COG3436	PFAM IS66 Orf2 family protein
U14A_RS16460	COG4372	Transposase
U14A_RS16510	COG4983	Phage plasmid primase, P4 family domain protein
U14A_RS16530	COG3468	outer membrane autotransporter barrel domain protein
U14A_RS16535	COG2020	methyltransferase activity
U14A_RS16565	COG2003	Belongs to the UPF0758 family
U14A_RS16660	COG0110	maltose O-acetyltransferase activity
U14A_RS16675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
U14A_RS16680	COG3193	protein, possibly involved in utilization of glycolate and propanediol
U14A_RS16685	COG0247	lactate metabolic process
U14A_RS16690	COG0277	FAD linked oxidase domain protein
U14A_RS16695	COG0277	FAD linked oxidase domain protein
U14A_RS16700	COG2186	Transcriptional regulator
U14A_RS16705	COG0456	acetyltransferase
U14A_RS16710	COG0318	PFAM AMP-dependent synthetase and ligase
U14A_RS16720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U14A_RS16725	COG0156	8-amino-7-oxononanoate synthase activity
U14A_RS16735	COG0795	lipopolysaccharide-transporting ATPase activity
U14A_RS16740	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
U14A_RS16750	COG2244	polysaccharide biosynthetic process
U14A_RS16755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
U14A_RS16760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
U14A_RS16765	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
U14A_RS16770	COG0306	phosphate transporter
U14A_RS16775	COG0754	glutathionylspermidine amidase activity
U14A_RS16780	COG0625	glutathione transferase activity
U14A_RS16785	COG0298	carbon dioxide binding
U14A_RS16795	COG1773	rubredoxin
U14A_RS16800	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
U14A_RS16805	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
U14A_RS16810	COG5557	Pfam Polysulphide reductase, NrfD
U14A_RS16815	COG0437	4 iron, 4 sulfur cluster binding
U14A_RS16820	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
U14A_RS16835	COG0667	Aldo Keto reductase
U14A_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS16850	COG0848	biopolymer transport protein
U14A_RS16855	COG0811	peptide transport
U14A_RS16860	COG0626	cystathionine gamma-synthase activity
U14A_RS16865	COG0586	Pfam SNARE associated Golgi protein
U14A_RS16870	COG2207	Transcriptional regulator
U14A_RS16875	COG1979	alcohol dehydrogenase
U14A_RS16880	COG0656	L-ascorbic acid biosynthetic process
U14A_RS16890	COG4238	major outer membrane lipoprotein
U14A_RS16895	COG1032	radical SAM domain protein
U14A_RS16900	COG2186	Transcriptional regulator
U14A_RS16905	COG0246	Mannitol dehydrogenase
U14A_RS16910	COG1063	alcohol dehydrogenase
U14A_RS16915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
U14A_RS16935	COG2132	Multicopper oxidase
U14A_RS16940	COG0204	Acyl-transferase
U14A_RS16945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
U14A_RS16950	COG4166	transmembrane transport
U14A_RS16955	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
U14A_RS16960	COG3111	PFAM Bacterial OB fold (BOF) protein
U14A_RS16965	COG0745	RESPONSE REGULATOR receiver
U14A_RS16970	COG0642	Histidine kinase
U14A_RS16985	COG2249	NAD(P)H dehydrogenase (quinone) activity
U14A_RS16990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
U14A_RS16995	COG1737	Transcriptional regulator
U14A_RS17005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS17010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS17015	COG1120	ATPase activity
U14A_RS17020	COG4774	siderophore transport
U14A_RS17025	COG0187	DNA topoisomerase II activity
U14A_RS17030	COG3150	esterase
U14A_RS17035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
U14A_RS17040	COG3151	Protein conserved in bacteria
U14A_RS17045	COG0494	nUDIX hydrolase
U14A_RS17050	COG1538	Outer membrane efflux protein
U14A_RS17060	COG0754	glutathionylspermidine amidase activity
U14A_RS17070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
U14A_RS17080	COG3384	dioxygenase
U14A_RS17090	COG3539	Fimbrial protein
U14A_RS17095	COG3188	usher protein
U14A_RS17100	COG3121	Chaperone
U14A_RS17105	COG3539	Fimbrial protein
U14A_RS17125	COG1585	Membrane protein implicated in regulation of membrane protease activity
U14A_RS17130	COG2268	Band 7 protein
U14A_RS17150	COG3025	triphosphatase activity
U14A_RS17155	COG4991	sh3 domain protein
U14A_RS17170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
U14A_RS17185	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
U14A_RS17190	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
U14A_RS17195	COG0471	metal ion transport
U14A_RS17205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
U14A_RS17210	COG0358	DNA primase activity
U14A_RS17215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
U14A_RS17230	COG2375	cellular response to nickel ion
U14A_RS17240	COG1695	Transcriptional regulator
U14A_RS17245	COG0840	transmembrane signaling receptor activity
U14A_RS17255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U14A_RS17260	COG1609	Transcriptional regulator
U14A_RS17265	COG3250	beta-galactosidase activity
U14A_RS17270	COG2731	YhcH YjgK YiaL family protein
U14A_RS17275	COG0531	amino acid
U14A_RS17285	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
U14A_RS17285	COG3408	Glycogen debranching enzyme
U14A_RS17290	COG1902	pentaerythritol trinitrate reductase activity
U14A_RS17290	COG0446	pyridine nucleotide-disulphide oxidoreductase
U14A_RS17295	COG5499	transcription regulator containing HTH domain
U14A_RS17300	COG4680	protein conserved in bacteria
U14A_RS17310	COG1451	nucleotide metabolic process
U14A_RS17315	COG2949	membrane
U14A_RS17320	COG0673	inositol 2-dehydrogenase activity
U14A_RS17325	COG0861	Integral membrane protein TerC family
U14A_RS17340	COG2721	sulfolactate sulfo-lyase activity
U14A_RS17350	COG2271	Major facilitator Superfamily
U14A_RS17355	COG2186	Transcriptional regulator
U14A_RS17360	COG0586	Pfam SNARE associated Golgi protein
U14A_RS17370	COG1422	Protein of unknown function (DUF1090)
U14A_RS17375	COG4575	ribosome binding
U14A_RS17380	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
U14A_RS17390	COG2259	Doxx family
U14A_RS17395	COG0435	Glutathione S-transferase
U14A_RS17400	COG3152	Membrane
U14A_RS17405	COG0583	DNA-binding transcription factor activity
U14A_RS17410	COG1741	Belongs to the pirin family
U14A_RS17440	COG1760	l-serine dehydratase
U14A_RS17445	COG0251	oxidation-reduction process
U14A_RS17450	COG1882	Formate acetyltransferase
U14A_RS17455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
U14A_RS17465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
U14A_RS17470	COG0583	DNA-binding transcription factor activity
U14A_RS17485	COG1929	Belongs to the glycerate kinase type-1 family
U14A_RS17490	COG2084	Dehydrogenase
U14A_RS17500	COG2271	Major facilitator Superfamily
U14A_RS17505	COG2721	sulfolactate sulfo-lyase activity
U14A_RS17510	COG2002	toxin-antitoxin pair type II binding
U14A_RS17520	COG1349	DNA-binding transcription factor activity
U14A_RS17530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS17540	COG3716	PTS system mannose fructose sorbose family IID component
U14A_RS17545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS17550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
U14A_RS17555	COG2222	sugar isomerase
U14A_RS17565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS17570	COG3715	PTS system
U14A_RS17575	COG3716	PTS system mannose fructose sorbose family IID component
U14A_RS17580	COG0363	glucosamine-6-phosphate deaminase activity
U14A_RS17585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
U14A_RS17605	COG2823	Periplasmic or secreted lipoprotein
U14A_RS17610	COG0701	Predicted permease
U14A_RS17615	COG0702	epimerase
U14A_RS17620	COG0693	protein deglycase activity
U14A_RS17635	COG3153	acetyltransferase
U14A_RS17640	COG3154	lipid carrier protein
U14A_RS17645	COG0826	peptidase U32
U14A_RS17650	COG0826	peptidase U32
U14A_RS17655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U14A_RS17660	COG0814	amino acid
U14A_RS17665	COG0513	Belongs to the DEAD box helicase family
U14A_RS17705	COG0195	Participates in both transcription termination and antitermination
U14A_RS17725	COG2194	sulfuric ester hydrolase activity
U14A_RS17735	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
U14A_RS17745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
U14A_RS17750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
U14A_RS17760	COG1534	Rna-binding protein
U14A_RS17765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
U14A_RS17770	COG2027	D-alanyl-D-alanine carboxypeptidase
U14A_RS17780	COG0697	spore germination
U14A_RS17795	COG0142	geranyltranstransferase activity
U14A_RS17800	COG3423	Transcriptional regulator
U14A_RS17810	COG5007	Belongs to the BolA IbaG family
U14A_RS17815	COG3113	response to antibiotic
U14A_RS17820	COG2854	intermembrane phospholipid transfer
U14A_RS17825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
U14A_RS17830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
U14A_RS17835	COG1127	ABC transporter
U14A_RS17840	COG0530	calcium, potassium:sodium antiporter activity
U14A_RS17845	COG0517	IMP dehydrogenase activity
U14A_RS17845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
U14A_RS17850	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
U14A_RS17855	COG3117	lipopolysaccharide transmembrane transporter activity
U14A_RS17860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
U14A_RS17865	COG1137	ATPase activity
U14A_RS17870	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
U14A_RS17875	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
U14A_RS17890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS17895	COG0515	serine threonine protein kinase
U14A_RS17905	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
U14A_RS17910	COG2198	Histidine kinase
U14A_RS17910	COG5002	protein histidine kinase activity
U14A_RS17910	COG0784	Response regulator, receiver
U14A_RS17915	COG1242	4 iron, 4 sulfur cluster binding
U14A_RS17920	COG0067	glutamate synthase
U14A_RS17920	COG0069	glutamate synthase activity
U14A_RS17920	COG0070	glutamate synthase
U14A_RS17925	COG0493	'glutamate synthase
U14A_RS17930	COG2731	YhcH YjgK YiaL family protein
U14A_RS17935	COG1940	carbohydrate kinase activity
U14A_RS17945	COG2814	Major facilitator Superfamily
U14A_RS17960	COG2969	positive regulation of protein catabolic process
U14A_RS17965	COG0625	glutathione transferase activity
U14A_RS17980	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
U14A_RS17985	COG3105	Protein conserved in bacteria
U14A_RS17990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U14A_RS17995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U14A_RS18015	COG2732	(Barnase) inhibitor
U14A_RS18035	COG0583	DNA-binding transcription factor activity
U14A_RS18040	COG0312	modulator of DNA gyrase
U14A_RS18045	COG3164	Protein of unknown function
U14A_RS18050	COG1530	ribonuclease E activity
U14A_RS18060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
U14A_RS18065	COG1792	Involved in formation and maintenance of cell shape
U14A_RS18070	COG1077	Cell shape determining protein MreB Mrl
U14A_RS18080	COG2200	EAL domain
U14A_RS18080	COG2199	diguanylate cyclase activity
U14A_RS18085	COG0604	alcohol dehydrogenase
U14A_RS18090	COG0511	ligase activity, forming carbon-carbon bonds
U14A_RS18095	COG0439	Biotin carboxylase
U14A_RS18105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS18110	COG1172	Belongs to the binding-protein-dependent transport system permease family
U14A_RS18115	COG1129	ABC transporter
U14A_RS18120	COG1879	ABC-type sugar transport system periplasmic component
U14A_RS18130	COG1349	DNA-binding transcription factor activity
U14A_RS18135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS18140	COG3924	membrane
U14A_RS18145	COG4145	pantothenate transmembrane transporter activity
U14A_RS18155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
U14A_RS18165	COG2189	Belongs to the N(4) N(6)-methyltransferase family
U14A_RS18175	COG1309	transcriptional regulator
U14A_RS18180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U14A_RS18185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U14A_RS18195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U14A_RS18200	COG4597	amino acid ABC transporter
U14A_RS18205	COG0765	amino acid transport
U14A_RS18210	COG1126	abc transporter atp-binding protein
U14A_RS18250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
U14A_RS18265	COG0009	L-threonylcarbamoyladenylate synthase
U14A_RS18270	COG0551	DNA topoisomerase type I activity
U14A_RS18280	COG0758	DNA mediated transformation
U14A_RS18300	COG0569	domain protein
U14A_RS18310	COG3036	rescue of stalled ribosome
U14A_RS18315	COG0789	Transcriptional regulator
U14A_RS18355	COG0201	protein transport
U14A_RS18445	COG0089	rRNA binding
U14A_RS18470	COG3267	Type II secretory pathway component ExeA
U14A_RS18470	COG3409	Peptidoglycan-binding domain 1 protein
U14A_RS18475	COG3031	protein transport across the cell outer membrane
U14A_RS18480	COG1450	Type ii and iii secretion system protein
U14A_RS18485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
U14A_RS18490	COG1459	type II secretion system
U14A_RS18495	COG2165	general secretion pathway protein
U14A_RS18500	COG2165	general secretion pathway protein
U14A_RS18505	COG2165	general secretion pathway protein
U14A_RS18510	COG4795	General secretion pathway protein
U14A_RS18515	COG3156	type II secretion system protein K
U14A_RS18520	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
U14A_RS18525	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
U14A_RS18535	COG2193	ferroxidase activity
U14A_RS18540	COG2906	2 iron, 2 sulfur cluster binding
U14A_RS18545	COG3979	chitinase
U14A_RS18585	COG2964	Protein conserved in bacteria
U14A_RS18590	COG0545	Peptidyl-prolyl cis-trans isomerase
U14A_RS18600	COG1047	Peptidyl-prolyl cis-trans
U14A_RS18605	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
U14A_RS18620	COG0488	(ABC) transporter
U14A_RS18625	COG0429	hydrolase of the alpha beta-hydrolase fold
U14A_RS18635	COG3954	Phosphoribulokinase
U14A_RS18640	COG1765	OsmC-like protein
U14A_RS18645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U14A_RS18650	COG1289	transmembrane transporter activity
U14A_RS18655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
U14A_RS18660	COG0512	Glutamine amidotransferase of anthranilate synthase
U14A_RS18665	COG2184	nucleotidyltransferase activity
U14A_RS18675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
U14A_RS18685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
U14A_RS18690	COG2146	nitrite reductase [NAD(P)H] activity
U14A_RS18695	COG2116	formate transmembrane transporter activity
U14A_RS18710	COG0626	cystathionine gamma-synthase activity
U14A_RS18725	COG1735	metal-dependent hydrolase with the TIM-barrel fold
U14A_RS18730	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
U14A_RS18735	COG3457	Alanine racemase
U14A_RS18745	COG2188	Transcriptional regulator
U14A_RS18755	COG0180	Tryptophanyl-tRNA synthetase
U14A_RS18765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
U14A_RS18770	COG0338	D12 class N6 adenine-specific DNA methyltransferase
U14A_RS18775	COG3266	domain, Protein
U14A_RS18790	COG4796	Type ii and iii secretion system protein
U14A_RS18805	COG3166	PFAM Fimbrial assembly family protein
U14A_RS18810	COG4972	Pilus assembly protein
U14A_RS18815	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
U14A_RS18820	COG0494	nUDIX hydrolase
U14A_RS18830	COG1011	Hydrolase
U14A_RS18835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
U14A_RS18845	COG0675	Transposase, IS605 OrfB family
U14A_RS18855	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
U14A_RS18875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
U14A_RS18880	COG2183	response to ionizing radiation
U14A_RS18885	COG1918	ferrous iron import across plasma membrane
U14A_RS18890	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
U14A_RS18900	COG5464	transposase or invertase
U14A_RS18905	COG0596	Alpha beta hydrolase
U14A_RS18920	COG2610	gluconate transmembrane transporter activity
U14A_RS18925	COG1640	4-alpha-glucanotransferase
U14A_RS18930	COG0058	SHG alpha-glucan phosphorylase activity
U14A_RS18945	COG4650	regulator
U14A_RS18950	COG1349	DNA-binding transcription factor activity
U14A_RS18965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
U14A_RS18980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
U14A_RS18985	COG0058	SHG alpha-glucan phosphorylase activity
U14A_RS19010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
U14A_RS19015	COG2095	MarC family integral membrane protein
U14A_RS19025	COG0514	ATP-dependent DNA helicase (RecQ)
U14A_RS19030	COG2610	gluconate transmembrane transporter activity
U14A_RS19035	COG3265	gluconokinase activity
U14A_RS19040	COG1609	Transcriptional regulator
U14A_RS19045	COG1741	Belongs to the pirin family
U14A_RS19050	COG0673	inositol 2-dehydrogenase activity
U14A_RS19055	COG1247	-acetyltransferase
U14A_RS19060	COG0405	Gamma-glutamyltransferase
U14A_RS19070	COG0584	glycerophosphoryl diester phosphodiesterase
U14A_RS19095	COG0410	ABC transporter
U14A_RS19100	COG0411	ABC transporter
U14A_RS19105	COG4177	L-phenylalanine transmembrane transporter activity
U14A_RS19110	COG0559	Belongs to the binding-protein-dependent transport system permease family
U14A_RS19115	COG0683	leucine binding
U14A_RS19120	COG0456	acetyltransferase
U14A_RS19135	COG0683	leucine binding
U14A_RS19140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
U14A_RS19145	COG2177	Part of the ABC transporter FtsEX involved in
U14A_RS19150	COG2884	Cell division ATP-binding protein ftsE
U14A_RS19155	COG0552	protein localization to endoplasmic reticulum
U14A_RS19160	COG0742	ribosomal rna small subunit methyltransferase
U14A_RS19165	COG3776	membrane
U14A_RS19175	COG3714	YhhN family
U14A_RS19190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
U14A_RS19200	COG0477	Major facilitator Superfamily
U14A_RS19205	COG0628	permease
U14A_RS19210	COG2091	lysine biosynthetic process via aminoadipic acid
U14A_RS19215	COG0747	negative chemotaxis
U14A_RS19220	COG0601	transmembrane transport
U14A_RS19225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U14A_RS19245	COG2188	Transcriptional regulator
U14A_RS19255	COG3414	Phosphotransferase system galactitol-specific IIB component
U14A_RS19260	COG3775	system Galactitol-specific IIC component
U14A_RS19275	COG0191	fructose-bisphosphate aldolase activity
U14A_RS19280	COG0842	Transport permease protein
U14A_RS19285	COG1129	ABC transporter
U14A_RS19285	COG0842	Transport permease protein
U14A_RS19290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U14A_RS19305	COG2081	HI0933 family
U14A_RS19310	COG0306	phosphate transporter
U14A_RS19320	COG0589	response to stress
U14A_RS19330	COG3104	oligopeptide transport
U14A_RS19340	COG0339	signal peptide processing
U14A_RS19345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
U14A_RS19350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U14A_RS19360	COG1393	Belongs to the ArsC family
U14A_RS19370	COG3065	identical protein binding
U14A_RS19375	COG2197	response regulator
U14A_RS19380	COG3720	iron ion transport
U14A_RS19385	COG4771	TonB-dependent receptor
U14A_RS19410	COG3721	Heme iron utilization protein
U14A_RS19420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS19430	COG1285	pathogenesis
U14A_RS19445	COG3247	response to pH
U14A_RS19450	COG2771	luxR family
U14A_RS19460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U14A_RS19465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U14A_RS19470	COG2207	Transcriptional regulator
U14A_RS19475	COG2207	Transcriptional regulator
U14A_RS19480	COG0076	glutamate decarboxylase activity
U14A_RS19485	COG1858	cytochrome C peroxidase
U14A_RS19495	COG2197	response regulator
U14A_RS19500	COG0583	DNA-binding transcription factor activity
U14A_RS19505	COG1295	ribonuclease BN
U14A_RS19510	COG0477	Major facilitator Superfamily
U14A_RS19515	COG2982	Protein involved in outer membrane biogenesis
U14A_RS19520	COG2200	EAL domain
U14A_RS19525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS19530	COG0612	Peptidase, M16
U14A_RS19540	COG2199	diguanylate cyclase activity
U14A_RS19540	COG2200	EAL domain
U14A_RS19545	COG0457	Tetratricopeptide repeat
U14A_RS19545	COG3118	belongs to the thioredoxin family
U14A_RS19550	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
U14A_RS19555	COG1215	transferase activity, transferring glycosyl groups
U14A_RS19560	COG1215	transferase activity, transferring glycosyl groups
U14A_RS19585	COG2194	sulfuric ester hydrolase activity
U14A_RS19615	COG0814	amino acid
U14A_RS19620	COG4608	Belongs to the ABC transporter superfamily
U14A_RS19625	COG0444	Belongs to the ABC transporter superfamily
U14A_RS19630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U14A_RS19635	COG0601	transmembrane transport
U14A_RS19645	COG0747	negative chemotaxis
U14A_RS19655	COG2194	sulfuric ester hydrolase activity
U14A_RS19660	COG2223	nitrite transmembrane transporter activity
U14A_RS19665	COG5571	outer membrane autotransporter
U14A_RS19670	COG2818	Glycosylase
U14A_RS19675	COG0456	acetyltransferase
U14A_RS19680	COG0243	molybdopterin cofactor binding
U14A_RS19685	COG2885	chlorophyll binding
U14A_RS19700	COG2944	sequence-specific DNA binding
U14A_RS19705	COG1278	Cold shock
U14A_RS19730	COG3274	enterobacterial common antigen metabolic process
U14A_RS19735	COG4682	membrane
U14A_RS19740	COG4682	membrane
U14A_RS19745	COG1070	Carbohydrate kinase
U14A_RS19755	COG4213	ABC transporter substrate-binding protein
U14A_RS19765	COG4214	carbohydrate transport
U14A_RS19770	COG1609	Transcriptional regulator
U14A_RS19770	COG2207	Transcriptional regulator
U14A_RS19775	COG2992	FlgJ-related protein
U14A_RS19780	COG0366	Alpha amylase catalytic
U14A_RS19785	COG3977	Valine--pyruvate aminotransferase
U14A_RS19790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
U14A_RS19795	COG1414	Transcriptional regulator
U14A_RS19805	COG2731	YhcH YjgK YiaL family protein
U14A_RS19815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
U14A_RS19820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
U14A_RS19825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
U14A_RS19830	COG1070	Carbohydrate kinase
U14A_RS19835	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
U14A_RS19840	COG3623	hexulose-6-phosphate isomerase
U14A_RS19845	COG0235	Class ii aldolase
U14A_RS19855	COG2211	Major facilitator Superfamily
U14A_RS19865	COG1012	belongs to the aldehyde dehydrogenase family
U14A_RS19875	COG1454	alcohol dehydrogenase
U14A_RS19880	COG3276	selenocysteine insertion sequence binding
U14A_RS19890	COG0625	glutathione transferase activity
U14A_RS19895	COG1566	PFAM secretion protein HlyD family protein
U14A_RS19905	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS19905	COG2213	PTS system mannitol-specific
U14A_RS19915	COG3722	fumarate hydratase activity
U14A_RS19935	COG5295	Hep Hag repeat protein
U14A_RS19940	COG1620	l-lactate permease
U14A_RS19945	COG2186	Transcriptional regulator
U14A_RS19955	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
U14A_RS19960	COG1045	serine acetyltransferase
U14A_RS19975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
U14A_RS19980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U14A_RS19990	COG4942	peptidase
U14A_RS19995	COG2861	carbohydrate metabolic process
U14A_RS20000	COG1216	Glycosyl transferase, family 2
U14A_RS20010	COG0156	8-amino-7-oxononanoate synthase activity
U14A_RS20020	COG0859	PFAM glycosyl transferase family 9
U14A_RS20025	COG0859	PFAM glycosyl transferase family 9
U14A_RS20030	COG3307	-O-antigen
U14A_RS20035	COG0859	PFAM glycosyl transferase family 9
U14A_RS20045	COG3642	lipopolysaccharide core region biosynthetic process
U14A_RS20050	COG1442	glycosyl transferase family 8
U14A_RS20055	COG1442	glycosyl transferase family 8
U14A_RS20060	COG0438	transferase activity, transferring glycosyl groups
U14A_RS20065	COG0438	transferase activity, transferring glycosyl groups
U14A_RS20065	COG4641	Protein conserved in bacteria
U14A_RS20070	COG0515	serine threonine protein kinase
U14A_RS20075	COG0438	transferase activity, transferring glycosyl groups
U14A_RS20080	COG0859	PFAM glycosyl transferase family 9
U14A_RS20085	COG1519	Transferase
U14A_RS20115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
U14A_RS20140	COG1561	YicC-like family, N-terminal region
U14A_RS20285	COG2860	membrane
U14A_RS20290	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
U14A_RS20295	COG0194	GDP metabolic process
U14A_RS20305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
U14A_RS20310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
U14A_RS20315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
U14A_RS20320	COG0786	glutamate:sodium symporter activity
U14A_RS20325	COG2233	PERMEase
U14A_RS20330	COG2982	Protein involved in outer membrane biogenesis
U14A_RS20340	COG1940	carbohydrate kinase activity
U14A_RS20355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS20355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS20360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS20365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS20365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS20365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS20370	COG3711	transcriptional antiterminator
U14A_RS20375	COG1501	Belongs to the glycosyl hydrolase 31 family
U14A_RS20380	COG2211	Major facilitator Superfamily
U14A_RS20400	COG0697	spore germination
U14A_RS20405	COG1464	Belongs to the NlpA lipoprotein family
U14A_RS20440	COG2252	PERMEase
U14A_RS20450	COG2271	Major facilitator Superfamily
U14A_RS20455	COG2271	Major facilitator Superfamily
U14A_RS20460	COG3851	Histidine kinase
U14A_RS20465	COG2197	response regulator
U14A_RS20475	COG0440	acetolactate synthase activity
U14A_RS20480	COG0028	Belongs to the TPP enzyme family
U14A_RS20490	COG2814	Major facilitator Superfamily
U14A_RS20495	COG0641	radical SAM
U14A_RS20505	COG2149	membrane
U14A_RS20515	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U14A_RS20520	COG2207	Transcriptional regulator
U14A_RS20540	COG5645	(Lipo)protein
U14A_RS20545	COG0823	Involved in the tonB-independent uptake of proteins
U14A_RS20555	COG2271	Major facilitator Superfamily
U14A_RS20565	COG0800	Aldolase
U14A_RS20570	COG3734	2-keto-3-deoxy-galactonokinase
U14A_RS20575	COG2186	Transcriptional regulator
U14A_RS20585	COG0561	phosphatase activity
U14A_RS20590	COG3753	Protein conserved in bacteria
U14A_RS20595	COG0187	DNA topoisomerase II activity
U14A_RS20605	COG0592	DNA-directed DNA polymerase activity
U14A_RS20655	COG0814	amino acid
U14A_RS20665	COG0583	DNA-binding transcription factor activity
U14A_RS20670	COG2091	lysine biosynthetic process via aminoadipic acid
U14A_RS20675	COG0431	NADPH-dependent FMN reductase
U14A_RS20680	COG2252	PERMEase
U14A_RS20685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
U14A_RS20695	COG3196	Protein conserved in bacteria
U14A_RS20700	COG0363	glucosamine-6-phosphate deaminase activity
U14A_RS20705	COG2382	esterase
U14A_RS20710	COG4580	involved in the transport of maltose and maltodextrins
U14A_RS20715	COG2723	6-phospho-beta-galactosidase activity
U14A_RS20720	COG1263	PTS System
U14A_RS20720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS20720	COG2190	(PTS) system
U14A_RS20730	COG0704	Plays a role in the regulation of phosphate uptake
U14A_RS20735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
U14A_RS20740	COG0581	inorganic phosphate transmembrane transporter activity
U14A_RS20745	COG0573	inorganic phosphate transmembrane transporter activity
U14A_RS20750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
U14A_RS20760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
U14A_RS20810	COG3312	ion transport
U14A_RS20825	COG0716	FMN binding
U14A_RS20830	COG1522	sequence-specific DNA binding
U14A_RS20855	COG1869	D-ribose catabolic process
U14A_RS20860	COG1129	ABC transporter
U14A_RS20865	COG1172	Belongs to the binding-protein-dependent transport system permease family
U14A_RS20870	COG1879	ABC-type sugar transport system periplasmic component
U14A_RS20875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS20880	COG1609	Transcriptional regulator
U14A_RS20885	COG0477	Major facilitator Superfamily
U14A_RS20890	COG2186	Transcriptional regulator
U14A_RS20930	COG3085	chromosome segregation
U14A_RS20935	COG0606	chelatase, subunit chli
U14A_RS20955	COG3978	acetolactate synthase activity
U14A_RS20960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
U14A_RS20970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
U14A_RS20975	COG0583	DNA-binding transcription factor activity
U14A_RS20985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U14A_RS20990	COG0210	DNA helicase
U14A_RS21005	COG3118	belongs to the thioredoxin family
U14A_RS21015	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
U14A_RS21020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
U14A_RS21025	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
U14A_RS21030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
U14A_RS21035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
U14A_RS21040	COG1088	dTDP-glucose 4,6-dehydratase activity
U14A_RS21045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
U14A_RS21050	COG0456	acetyltransferase
U14A_RS21055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
U14A_RS21060	COG2244	polysaccharide biosynthetic process
U14A_RS21080	COG1113	amino acid transport
U14A_RS21105	COG0641	radical SAM
U14A_RS21110	COG3119	arylsulfatase activity
U14A_RS21120	COG3071	HemY protein
U14A_RS21125	COG2959	enzyme of heme biosynthesis
U14A_RS21130	COG1587	Uroporphyrinogen-III synthase
U14A_RS21140	COG3072	Adenylate cyclase
U14A_RS21155	COG5567	small periplasmic lipoprotein
U14A_RS21165	COG3159	Protein conserved in bacteria
U14A_RS21175	COG1011	Hydrolase
U14A_RS21180	COG0210	DNA helicase
U14A_RS21185	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
U14A_RS21190	COG3698	Phosphodiester glycosidase
U14A_RS21195	COG0598	Magnesium transport protein CorA
U14A_RS21210	COG2962	Rard protein
U14A_RS21215	COG2050	protein possibly involved in aromatic compounds catabolism
U14A_RS21220	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
U14A_RS21225	COG0514	ATP-dependent DNA helicase (RecQ)
U14A_RS21230	COG1280	lysine exporter protein (LysE YggA)
U14A_RS21240	COG1280	lysine exporter protein (LysE YggA)
U14A_RS21245	COG2267	carboxylic ester hydrolase activity
U14A_RS21250	COG0561	phosphatase activity
U14A_RS21255	COG0697	spore germination
U14A_RS21260	COG0583	DNA-binding transcription factor activity
U14A_RS21275	COG1263	PTS System
U14A_RS21275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS21275	COG2190	(PTS) system
U14A_RS21280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
U14A_RS21285	COG1737	Transcriptional regulator
U14A_RS21290	COG0583	DNA-binding transcription factor activity
U14A_RS21295	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
U14A_RS21305	COG0549	Belongs to the carbamate kinase family
U14A_RS21310	COG1304	FMN binding
U14A_RS21315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
U14A_RS21325	COG1335	isochorismatase
U14A_RS21330	COG0412	Dienelactone hydrolase
U14A_RS21335	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
U14A_RS21355	COG0800	Aldolase
U14A_RS21360	COG3734	2-keto-3-deoxy-galactonokinase
U14A_RS21365	COG1414	Transcriptional regulator
U14A_RS21370	COG1322	Protein conserved in bacteria
U14A_RS21380	COG3165	ubiquinone biosynthetic process from chorismate
U14A_RS21390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
U14A_RS21400	COG0805	protein transport
U14A_RS21415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
U14A_RS21420	COG0543	2 iron, 2 sulfur cluster binding
U14A_RS21440	COG1739	Uncharacterized protein family UPF0029
U14A_RS21445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
U14A_RS21450	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
U14A_RS21475	COG1763	Mo-molybdopterin cofactor biosynthetic process
U14A_RS21480	COG0746	molybdenum cofactor guanylyltransferase activity
U14A_RS21485	COG3084	Protein conserved in bacteria
U14A_RS21490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
U14A_RS21495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
U14A_RS21505	COG0204	Acyl-transferase
U14A_RS21515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
U14A_RS21515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
U14A_RS21530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
U14A_RS21540	COG2204	response regulator
U14A_RS21545	COG3852	Histidine kinase
U14A_RS21550	COG0174	glutamine synthetase
U14A_RS21555	COG1217	gtp-binding protein TYPA
U14A_RS21560	COG1349	DNA-binding transcription factor activity
U14A_RS21565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U14A_RS21570	COG2084	Dehydrogenase
U14A_RS21575	COG3684	Belongs to the aldolase LacD family
U14A_RS21580	COG1063	alcohol dehydrogenase
U14A_RS21590	COG0477	Major facilitator Superfamily
U14A_RS21600	COG1011	Hydrolase
U14A_RS21615	COG0456	acetyltransferase
U14A_RS21625	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
U14A_RS21650	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
U14A_RS21665	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
U14A_RS21675	COG2864	formate dehydrogenase
U14A_RS21680	COG0437	4 iron, 4 sulfur cluster binding
U14A_RS21740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
U14A_RS21750	COG2258	MOSC domain
U14A_RS21755	COG2205	protein histidine kinase activity
U14A_RS21760	COG0745	RESPONSE REGULATOR receiver
U14A_RS21765	COG3678	ATP-independent chaperone mediated protein folding
U14A_RS21780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
U14A_RS21800	COG3152	Membrane
U14A_RS21805	COG3691	Protein conserved in bacteria
U14A_RS21810	COG0589	response to stress
U14A_RS21820	COG1494	fructose-1,6-bisphosphatase
U14A_RS21830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
U14A_RS21845	COG1575	Belongs to the MenA family. Type 1 subfamily
U14A_RS21860	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
U14A_RS21865	COG1609	Transcriptional regulator
U14A_RS21870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
U14A_RS21880	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
U14A_RS21890	COG0626	cystathionine gamma-synthase activity
U14A_RS21895	COG0460	homoserine dehydrogenase
U14A_RS21895	COG0527	aspartate kinase activity
U14A_RS21905	COG0737	Belongs to the 5'-nucleotidase family
U14A_RS21910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
U14A_RS21920	COG0697	spore germination
U14A_RS21925	COG3738	Protein conserved in bacteria
U14A_RS21930	COG0371	Dehydrogenase
U14A_RS21935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
U14A_RS21940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS21940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS21940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
U14A_RS21945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS21950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS21955	COG1882	Formate acetyltransferase
U14A_RS21960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
U14A_RS21965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U14A_RS21970	COG2207	Transcriptional regulator
U14A_RS21975	COG2194	sulfuric ester hydrolase activity
U14A_RS21990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
U14A_RS22005	COG0583	DNA-binding transcription factor activity
U14A_RS22015	COG1473	amidohydrolase
U14A_RS22020	COG0477	Major facilitator Superfamily
U14A_RS22025	COG1309	transcriptional regulator
U14A_RS22080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
U14A_RS22080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
U14A_RS22115	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
U14A_RS22120	COG0250	Participates in transcription elongation, termination and antitermination
U14A_RS22155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
U14A_RS22165	COG2104	thiamine diphosphate biosynthetic process
U14A_RS22170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
U14A_RS22205	COG3068	Protein conserved in bacteria
U14A_RS22220	COG3678	ATP-independent chaperone mediated protein folding
U14A_RS22225	COG4191	Histidine kinase
U14A_RS22230	COG2204	response regulator
U14A_RS22235	COG0151	Belongs to the GarS family
U14A_RS22270	COG0456	acetyltransferase
U14A_RS22280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
U14A_RS22285	COG2224	Isocitrate lyase
U14A_RS22295	COG1414	Transcriptional regulator
U14A_RS22300	COG0646	methionine synthase
U14A_RS22300	COG1410	methionine synthase
U14A_RS22315	COG1283	sodium-dependent phosphate transmembrane transporter activity
U14A_RS22360	COG1187	pseudouridine synthase activity
U14A_RS22370	COG0527	aspartate kinase activity
U14A_RS22400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
U14A_RS22415	COG3833	ABC-type maltose transport systems, permease component
U14A_RS22420	COG1175	transmembrane transport
U14A_RS22425	COG2182	Extracellular solute-binding protein
U14A_RS22430	COG3842	ATPase activity
U14A_RS22460	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
U14A_RS22470	COG0534	Mate efflux family protein
U14A_RS22475	COG3237	CsbD-like
U14A_RS22480	COG0735	belongs to the Fur family
U14A_RS22485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
U14A_RS22495	COG0604	alcohol dehydrogenase
U14A_RS22500	COG1053	succinate dehydrogenase
U14A_RS22505	COG1914	H( )-stimulated, divalent metal cation uptake system
U14A_RS22510	COG1024	Enoyl-CoA hydratase
U14A_RS22520	COG1609	Transcriptional regulator
U14A_RS22525	COG0305	Participates in initiation and elongation during chromosome replication
U14A_RS22530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
U14A_RS22535	COG3201	nicotinamide mononucleotide transporter
U14A_RS22545	COG1448	Aminotransferase
U14A_RS22550	COG0567	Dehydrogenase, E1 component
U14A_RS22560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U14A_RS22565	COG0045	succinate-CoA ligase (ADP-forming) activity
U14A_RS22570	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
U14A_RS22575	COG0471	metal ion transport
U14A_RS22580	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
U14A_RS22585	COG2204	response regulator
U14A_RS22595	COG3700	Belongs to the class B bacterial acid phosphatase family
U14A_RS22600	COG0432	Pfam Uncharacterised protein family UPF0047
U14A_RS22605	COG2315	Protein conserved in bacteria
U14A_RS22610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
U14A_RS22615	COG0629	single-stranded DNA binding
U14A_RS22625	COG4943	cyclic-guanylate-specific phosphodiesterase activity
U14A_RS22630	COG2207	Transcriptional regulator
U14A_RS22635	COG0789	Transcriptional regulator
U14A_RS22640	COG2252	PERMEase
U14A_RS22645	COG0025	NhaP-type Na H and K H
U14A_RS22650	COG0583	DNA-binding transcription factor activity
U14A_RS22655	COG1380	Effector of murein hydrolase LrgA
U14A_RS22660	COG1346	cytolysis
U14A_RS22670	COG3162	membrane
U14A_RS22675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
U14A_RS22690	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
U14A_RS22695	COG0437	4 iron, 4 sulfur cluster binding
U14A_RS22700	COG3301	Polysulphide reductase, NrfD
U14A_RS22705	COG1138	Cytochrome C-type biogenesis protein
U14A_RS22710	COG3088	subunit of a heme lyase
U14A_RS22715	COG4235	cytochrome complex assembly
U14A_RS22720	COG1301	dicarboxylic acid transport
U14A_RS22725	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
U14A_RS22730	COG4608	Belongs to the ABC transporter superfamily
U14A_RS22735	COG0444	Belongs to the ABC transporter superfamily
U14A_RS22740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U14A_RS22745	COG0601	transmembrane transport
U14A_RS22765	COG1289	transmembrane transporter activity
U14A_RS22770	COG1566	PFAM secretion protein HlyD family protein
U14A_RS22780	COG2015	COG2015, Alkyl sulfatase and related hydrolases
U14A_RS22785	COG1940	carbohydrate kinase activity
U14A_RS22790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
U14A_RS22795	COG1172	Belongs to the binding-protein-dependent transport system permease family
U14A_RS22800	COG1129	ABC transporter
U14A_RS22805	COG1879	ABC-type sugar transport system periplasmic component
U14A_RS22810	COG1737	Transcriptional regulator
U14A_RS22815	COG0698	ribose 5-phosphate isomerase
U14A_RS22825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
U14A_RS22830	COG0456	acetyltransferase
U14A_RS22840	COG3454	Phosphonate metabolism
U14A_RS22845	COG4778	phosphonate C-P lyase system protein PhnL
U14A_RS22850	COG4107	phosphonate C-P lyase system protein PhnK
U14A_RS22855	COG3627	carbon phosphorus lyase activity
U14A_RS22860	COG3626	phosphonate metabolism
U14A_RS22865	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
U14A_RS22870	COG3624	Phosphonate C-P lyase system protein PhnG
U14A_RS22875	COG2188	Transcriptional regulator
U14A_RS22880	COG3639	organic phosphonate transmembrane transporter activity
U14A_RS22885	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
U14A_RS22895	COG2764	glyoxalase bleomycin resistance protein dioxygenase
U14A_RS22900	COG2824	Alkylphosphonate utilization operon protein PhnA
U14A_RS22915	COG0477	Major facilitator Superfamily
U14A_RS22925	COG0642	Histidine kinase
U14A_RS22930	COG0745	RESPONSE REGULATOR receiver
U14A_RS22935	COG2194	sulfuric ester hydrolase activity
U14A_RS22940	COG0531	amino acid
U14A_RS22945	COG2207	Transcriptional regulator
U14A_RS22950	COG1982	Orn Lys Arg decarboxylase major
U14A_RS22955	COG2169	Transcriptional regulator
U14A_RS22960	COG1486	melibiose metabolic process
U14A_RS22965	COG3647	Membrane
U14A_RS22970	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
U14A_RS22970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
U14A_RS22975	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
U14A_RS22980	COG4565	transcriptional regulatory protein
U14A_RS22985	COG3290	protein histidine kinase activity
U14A_RS22990	COG3592	Divergent 4Fe-4S mono-cluster
U14A_RS22995	COG2388	GCN5-related N-acetyl-transferase
U14A_RS23005	COG3121	Chaperone
U14A_RS23015	COG3210	domain, Protein
U14A_RS23015	COG3468	outer membrane autotransporter barrel domain protein
U14A_RS23035	COG2388	GCN5-related N-acetyl-transferase
U14A_RS23050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
U14A_RS23055	COG3104	oligopeptide transport
U14A_RS23060	COG1982	Orn Lys Arg decarboxylase major
U14A_RS23065	COG0531	amino acid
U14A_RS23075	COG3710	Transcriptional regulator
U14A_RS23110	COG2003	Belongs to the UPF0758 family
U14A_RS23135	COG2378	regulation of single-species biofilm formation
U14A_RS23140	COG3596	GTP binding
U14A_RS23185	COG1309	transcriptional regulator
U14A_RS23205	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
U14A_RS23210	COG2207	Transcriptional regulator
U14A_RS23215	COG2972	Histidine kinase
U14A_RS23225	COG3344	reverse transcriptase
U14A_RS23245	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
U14A_RS23250	COG1882	Formate acetyltransferase
U14A_RS23255	COG0693	protein deglycase activity
U14A_RS23265	COG1012	belongs to the aldehyde dehydrogenase family
U14A_RS23300	COG4820	ethanolamine utilization protein (EutJ)
U14A_RS23305	COG4869	propanediol catabolic process
U14A_RS23365	COG0604	alcohol dehydrogenase
U14A_RS23380	COG0531	amino acid
U14A_RS23385	COG1982	Orn Lys Arg decarboxylase major
U14A_RS23390	COG0531	amino acid
U14A_RS23440	COG0582	viral genome integration into host DNA
U14A_RS23450	COG1309	transcriptional regulator
U14A_RS23455	COG4232	protein-disulfide reductase activity
U14A_RS23465	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
U14A_RS23470	COG1027	Aspartate ammonia-lyase
U14A_RS23475	COG3030	protein affecting phage T7 exclusion by the F plasmid
U14A_RS23480	COG0531	amino acid
U14A_RS23505	COG1509	lysine 2,3-aminomutase activity
U14A_RS23515	COG5510	response to toxic substance
U14A_RS23520	COG5510	response to toxic substance
U14A_RS23525	COG2076	Multidrug Resistance protein
U14A_RS23530	COG3040	lipid binding
U14A_RS23535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U14A_RS23550	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
U14A_RS23555	COG1053	succinate dehydrogenase
U14A_RS23565	COG0531	amino acid
U14A_RS23575	COG1511	domain protein
U14A_RS23575	COG3264	Mechanosensitive ion channel
U14A_RS23615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
U14A_RS23620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
U14A_RS23620	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
U14A_RS23625	COG0802	atpase or kinase
U14A_RS23630	COG0860	N-Acetylmuramoyl-L-alanine amidase
U14A_RS23650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
U14A_RS23655	COG0330	HflC and HflK could
U14A_RS23660	COG0330	HflC and HflK could
U14A_RS23665	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
U14A_RS23680	COG0557	exoribonuclease II activity
U14A_RS23685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
U14A_RS23690	COG3789	protein conserved in bacteria
U14A_RS23695	COG1842	Phage shock protein A
U14A_RS23705	COG3766	membrane
U14A_RS23710	COG5463	Belongs to the UPF0441 family
U14A_RS23715	COG0754	glutathionylspermidine amidase activity
U14A_RS23720	COG1960	acyl-CoA dehydrogenase activity
U14A_RS23730	COG3650	response to hydrogen peroxide
U14A_RS23735	COG1073	alpha beta
U14A_RS23750	COG3037	sugar-specific permease SgaT UlaA
U14A_RS23755	COG3414	Phosphotransferase system galactitol-specific IIB component
U14A_RS23775	COG0235	Class ii aldolase
U14A_RS23795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
U14A_RS23825	COG2271	Major facilitator Superfamily
U14A_RS23830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
U14A_RS23835	COG4670	ketone body catabolic process
U14A_RS23840	COG1024	Enoyl-CoA hydratase
U14A_RS23855	COG1309	transcriptional regulator
U14A_RS23860	COG3061	Opacity-associated protein A
U14A_RS23870	COG0545	Peptidyl-prolyl cis-trans isomerase
U14A_RS23875	COG1113	amino acid transport
U14A_RS23885	COG0697	spore germination
U14A_RS23890	COG0702	epimerase
U14A_RS23895	COG1733	regulation of RNA biosynthetic process
U14A_RS23900	COG0737	Belongs to the 5'-nucleotidase family
U14A_RS23905	COG1218	3'(2'),5'-bisphosphate nucleotidase
U14A_RS23910	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
U14A_RS23920	COG1253	flavin adenine dinucleotide binding
U14A_RS23930	COG0729	surface antigen
U14A_RS23935	COG2911	Protein conserved in bacteria
U14A_RS23940	COG2105	PFAM AIG2 family protein
U14A_RS23945	COG2336	PFAM SpoVT AbrB
U14A_RS23950	COG2337	Toxic component of a toxin-antitoxin (TA) module
U14A_RS23955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
U14A_RS23960	COG1879	ABC-type sugar transport system periplasmic component
U14A_RS23965	COG1129	ABC transporter
U14A_RS23970	COG1172	Belongs to the binding-protein-dependent transport system permease family
U14A_RS23975	COG1172	Belongs to the binding-protein-dependent transport system permease family
U14A_RS23985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
U14A_RS23995	COG0312	modulator of DNA gyrase
U14A_RS24000	COG3783	Cytochrome b(562)
U14A_RS24005	COG0602	queuosine metabolic process
U14A_RS24010	COG1328	CTP reductase activity
U14A_RS24015	COG0366	Alpha amylase catalytic
U14A_RS24020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U14A_RS24020	COG1263	PTS System
U14A_RS24025	COG1609	Transcriptional regulator
U14A_RS24035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
U14A_RS24040	COG0251	oxidation-reduction process
U14A_RS24060	COG0251	oxidation-reduction process
U14A_RS24065	COG1028	Short-chain dehydrogenase reductase Sdr
U14A_RS24070	COG1309	transcriptional regulator
U14A_RS24075	COG2731	YhcH YjgK YiaL family protein
U14A_RS24090	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
U14A_RS24095	COG0456	acetyltransferase
U14A_RS24100	COG4269	membrane
U14A_RS24110	COG2927	DNA polymerase III (CHI subunit)
U14A_RS24120	COG0795	lipopolysaccharide-transporting ATPase activity
U14A_RS24125	COG0795	lipopolysaccharide-transporting ATPase activity
U14A_RS24130	COG0433	COG0433 Predicted ATPase
U14A_RS24135	COG1064	alcohol dehydrogenase
U14A_RS24175	COG1414	Transcriptional regulator
U14A_RS24180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U14A_RS24185	COG2721	sulfolactate sulfo-lyase activity
U14A_RS24190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
U14A_RS24195	COG2271	Major facilitator Superfamily
U14A_RS24225	COG3436	PFAM IS66 Orf2 family protein
U14A_RS24230	COG4372	Transposase
U14A_RS24240	COG0738	Major facilitator superfamily
U14A_RS24250	COG1349	DNA-binding transcription factor activity
U14A_RS24255	COG0440	acetolactate synthase activity
U14A_RS24270	COG0604	alcohol dehydrogenase
U14A_RS24295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
U14A_RS24310	COG2085	NADP oxidoreductase coenzyme F420-dependent
U14A_RS24315	COG1120	ATPase activity
U14A_RS24320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS24325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U14A_RS24330	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
U14A_RS24335	COG4772	TonB-dependent receptor
U14A_RS24340	COG3712	iron ion homeostasis
U14A_RS24345	COG1595	DNA-templated transcription, initiation
U14A_RS24365	COG4372	Transposase
U14A_RS24370	COG3436	PFAM IS66 Orf2 family protein
U14A_RS24455	COG3468	outer membrane autotransporter barrel domain protein
U14A_RS24475	COG1484	DNA-dependent DNA replication
U14A_RS24480	COG4584	PFAM Integrase catalytic
U14A_RS24500	COG2003	Belongs to the UPF0758 family
U14A_RS24525	COG3436	PFAM IS66 Orf2 family protein
U14A_RS24575	COG1401	restriction endodeoxyribonuclease activity
U14A_RS24585	COG1215	transferase activity, transferring glycosyl groups
U14A_RS24605	COG3153	acetyltransferase
U14A_RS24610	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
U14A_RS24620	COG1363	Peptidase, m42
U14A_RS24625	COG3414	Phosphotransferase system galactitol-specific IIB component
U14A_RS24630	COG3775	system Galactitol-specific IIC component
U14A_RS24635	COG0434	BtpA family
U14A_RS24640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U14A_RS24645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
U14A_RS24650	COG1349	DNA-binding transcription factor activity
U14A_RS24655	COG1414	Transcriptional regulator
U14A_RS24660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U14A_RS24665	COG0129	dihydroxy-acid dehydratase activity
U14A_RS24670	COG2610	gluconate transmembrane transporter activity
U14A_RS24675	COG2390	Transcriptional regulator
U14A_RS24705	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
U14A_RS24705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U14A_RS24715	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
U14A_RS24720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
U14A_RS24740	COG0582	viral genome integration into host DNA
U14A_RS24745	COG4974	Belongs to the 'phage' integrase family
U14A_RS24755	COG3539	Fimbrial protein
U14A_RS24760	COG3121	Chaperone
U14A_RS24765	COG3188	usher protein
U14A_RS24770	COG3539	Fimbrial protein
U14A_RS24775	COG3539	Fimbrial protein
U14A_RS24780	COG3539	Fimbrial protein
U14A_RS24785	COG2610	gluconate transmembrane transporter activity
U14A_RS24795	COG0246	Mannitol dehydrogenase
U14A_RS24800	COG2186	Transcriptional regulator
U14A_RS24820	COG0583	DNA-binding transcription factor activity
U14A_RS24825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
U14A_RS24830	COG0700	Nucleoside recognition
U14A_RS24835	COG3366	ferrous iron transmembrane transporter activity
U14A_RS24845	COG0477	Major facilitator Superfamily
U14A_RS24860	COG1924	4 iron, 4 sulfur cluster binding
U14A_RS24865	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
U14A_RS24870	COG2733	membrane
U14A_RS24875	COG2814	Major facilitator Superfamily
U14A_RS24895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U14A_RS24900	COG5457	Domain of unknown function (DUF1127)
U14A_RS24910	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
U14A_RS24915	COG0732	type I restriction modification DNA specificity domain
U14A_RS24920	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
U14A_RS24925	COG1715	Restriction endonuclease
U14A_RS24940	COG0523	cobalamin synthesis protein
U14A_RS24945	COG2879	small protein
U14A_RS24950	COG1966	Carbon starvation protein
U14A_RS24955	COG0840	transmembrane signaling receptor activity
U14A_RS24960	COG2271	Major facilitator Superfamily
U14A_RS24965	COG1802	Transcriptional regulator
U14A_RS24970	COG1063	alcohol dehydrogenase
U14A_RS24985	COG1484	DNA-dependent DNA replication
U14A_RS25000	COG2966	Psort location CytoplasmicMembrane, score
U14A_RS25005	COG2197	response regulator
U14A_RS25010	COG2197	response regulator
U14A_RS25015	COG4114	ferric iron reductase
U14A_RS25040	COG2813	Specifically methylates the guanine in position
U14A_RS25045	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
U14A_RS25050	COG0456	acetyltransferase
U14A_RS25055	COG1011	Hydrolase
U14A_RS25065	COG2823	Periplasmic or secreted lipoprotein
U14A_RS25075	COG4667	esterase of the alpha-beta hydrolase superfamily
U14A_RS25080	COG0084	hydrolase, TatD family'
U14A_RS25085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
U14A_RS25090	COG1328	CTP reductase activity
U14A_RS25115	COG3550	peptidyl-serine autophosphorylation
U14A_RS25125	COG3726	membrane protein affecting hemolysin expression
U14A_RS25130	COG0560	Phosphoserine phosphatase
U14A_RS25135	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
U14A_RS25140	COG3172	ATPase kinase involved in NAD metabolism
U14A_RS25140	COG1056	cytidyltransferase-related domain
U14A_RS25145	COG0488	(ABC) transporter
U14A_RS25150	COG0741	lytic transglycosylase activity
U14A_RS25170	COG3708	Transcriptional regulator
U14A_RS25170	COG2207	Transcriptional regulator
U14A_RS25175	COG3045	CreA protein
U14A_RS25180	COG0745	RESPONSE REGULATOR receiver
U14A_RS25185	COG2205	protein histidine kinase activity
U14A_RS25190	COG4452	Inner membrane protein CreD
U14A_RS25195	COG0745	RESPONSE REGULATOR receiver
U14A_RS25205	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
U14A_RS25475	COG3039	Transposase
U14A_RS25480	COG0833	amino acid
U14A_RS25485	COG2040	homocysteine
U14A_RS25550	COG4771	TonB-dependent receptor
U14A_RS25580	COG3436	PFAM IS66 Orf2 family protein
U14A_RS25595	COG3344	reverse transcriptase
U14A_RS25695	COG3344	reverse transcriptase
U14A_RS25715	COG1136	(ABC) transporter
U14A_RS25715	COG0577	efflux transmembrane transporter activity
U14A_RS25720	COG1136	(ABC) transporter
U14A_RS25720	COG0577	efflux transmembrane transporter activity
U14A_RS25725	COG1136	(ABC) transporter
U14A_RS25725	COG0577	efflux transmembrane transporter activity
U14A_RS25740	COG0672	)-iron permease
U14A_RS25750	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
U14A_RS25755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U14A_RS25825	COG1695	Transcriptional regulator
U14A_RS25860	COG3173	Aminoglycoside phosphotransferase
U14A_RS25915	COG0697	spore germination
U14A_RS26000	COG4372	Transposase
U14A_RS26005	COG3436	PFAM IS66 Orf2 family protein
U14A_RS26025	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
U14A_RS26100	COG3039	Transposase
U14A_RS26670	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities